ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A01 compound treatment 284.0 91.7 0.48 289.1 102.0 0.53 0.712 0.9988 1315851 ChemDiv1_002817 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)C(C)(C)C)c3ccccc3c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A02 compound treatment 285.5 93.2 0.49 285.8 98.4 0.51 0.7054 0.9997 1971663 ChemDiv1_002818 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A03 compound treatment 279.8 87.5 0.46 287.1 99.7 0.52 0.6891 0.998 1971664 ChemDiv1_002819 COc1ccc(cc1)C(=O)Oc2ccc(C)cc2/C=C/3\Sc4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A04 compound treatment 283.3 91.0 0.47 286.4 99.0 0.51 0.6995 0.9992 1971665 ChemDiv1_002820 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccccc4OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A05 compound treatment 283.3 91.0 0.47 284.5 97.1 0.5 0.6925 0.9995 1971666 ChemDiv1_002821 O=c1oc(/C=C/c2ccco2)nc3sc4CCCCc4c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A06 compound treatment 287.9 95.6 0.5 285.2 97.8 0.51 0.712 1.0 1971667 ChemDiv1_002822 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(OC)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A07 compound treatment 281.9 89.6 0.47 282.0 94.6 0.49 0.6781 0.9997 1971668 ChemDiv1_002823 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(Cl)cc3)C(=O)O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A08 compound treatment 283.5 91.2 0.48 288.2 101.0 0.52 0.7068 0.9989 1971669 ChemDiv1_002824 COC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cc(Cl)ccc3Cl)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A09 compound treatment 282.8 90.5 0.47 284.5 97.1 0.5 0.6907 0.9995 1971670 ChemDiv1_002825 COc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)Nc4ccccc4OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A10 compound treatment 283.9 91.6 0.48 279.0 91.6 0.48 0.6745 1.0 1971671 ChemDiv1_002826 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A11 compound treatment 281.0 88.7 0.46 284.4 97.0 0.5 0.6836 0.9991 1971672 ChemDiv1_002827 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A12 compound treatment 281.9 89.6 0.47 286.0 98.6 0.51 0.6928 0.999 1941012 ChemDiv1_002828 ClC1=CCC2C(C1)C(=O)N(CN(CN3C(=O)C4CC=C(Cl)CC4C3=O)Cc5ccco5)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A13 compound treatment 280.1 87.8 0.46 283.1 95.7 0.5 0.6755 0.9992 1971673 ChemDiv1_002829 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)cc3C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A14 compound treatment 282.0 89.7 0.47 279.4 92.0 0.48 0.669 0.9999 1971674 ChemDiv1_002830 CC(C)Nc1nc(NC(C)C)nc(OCCNC(=O)COc2ccc(Cl)cc2Cl)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A15 compound treatment 283.5 91.2 0.48 283.7 96.3 0.5 0.6903 0.9997 1971675 ChemDiv1_002831 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(cc3)C(=O)OC)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A16 compound treatment 286.1 93.8 0.49 279.9 92.5 0.48 0.6859 1.0 1302605 ChemDiv1_002832 CCN1C(=O)C(O)(C2COC(C)(C)CC2=O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A17 compound treatment 279.9 87.6 0.46 280.0 92.6 0.48 0.6634 0.9997 1971676 ChemDiv1_002833 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(cc3)C(=O)OC)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A18 compound treatment 281.7 89.4 0.47 282.1 94.7 0.49 0.6778 0.9996 1348235 ChemDiv1_002834 COC(=O)CN(C#N)c1nc(NCc2ccccc2)nc(OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A19 compound treatment 280.0 87.7 0.46 280.0 92.6 0.48 0.6638 0.9997 1971677 ChemDiv1_002835 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(OC)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A20 compound treatment 284.5 92.2 0.48 277.8 90.4 0.47 0.6723 0.9999 1971678 ChemDiv1_002836 CCOC(=O)c1sc(NC(=O)Cn2nc([N+](=O)[O-])c([N+](=O)[O-])c2C)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A21 compound treatment 280.5 88.2 0.46 279.2 91.8 0.48 0.6627 0.9998 1971679 ChemDiv1_002837 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(Cl)c(c3)C(F)(F)F)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A22 compound treatment 282.8 90.5 0.47 282.3 94.9 0.49 0.6826 0.9998 1971680 ChemDiv1_002838 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)Nc4ccc(cc4)C(=O)C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A23 mock treatment 285.3 93.0 0.49 279.0 91.6 0.48 0.6797 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 A24 mock treatment 75.9 -116.0 -0.61 78.3 -109.0 -0.57 -0.8304 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B01 compound treatment 281.7 89.4 0.47 287.7 100.0 0.52 0.6984 0.9985 1971681 ChemDiv1_002839 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)Nc4cccc(c4)C(=O)C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B02 compound treatment 284.4 92.1 0.48 287.0 99.6 0.52 0.7057 0.9993 1971682 ChemDiv1_002840 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B03 compound treatment 289.0 96.7 0.5 290.1 103.0 0.53 0.7341 0.9996 1971683 ChemDiv1_002841 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4c(C)n(C)n(c5ccccc5)c4=O)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B04 compound treatment 283.0 90.7 0.47 280.1 92.7 0.48 0.6752 1.0 1971684 ChemDiv1_002842 Cc1ccc2[nH]c(SCC(=O)Nc3ccccc3C(F)(F)F)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B05 compound treatment 286.7 94.4 0.49 286.8 99.4 0.52 0.7135 0.9997 1971685 ChemDiv1_002843 CN(Cc1ccccc1)C(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B06 compound treatment 282.0 89.7 0.47 282.9 95.5 0.5 0.6818 0.9996 1324538 ChemDiv1_002844 COC(=O)c1ccccc1NC(=O)CSc2nc3cc(OC)ccc3[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B07 compound treatment 284.7 92.4 0.48 290.1 103.0 0.53 0.7182 0.9987 1971686 ChemDiv1_002845 Fc1ccc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)c(F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B08 compound treatment 285.2 92.9 0.48 285.3 97.9 0.51 0.7024 0.9997 1259663 ChemDiv1_002846 O=C(Nc1ccc(cc1)c2cc3ccccc3oc2=O)c4ccc5OCCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B09 compound treatment 286.3 94.0 0.49 283.0 95.6 0.5 0.6981 1.0 1971687 ChemDiv1_002847 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCOCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B10 compound treatment 285.9 93.6 0.49 282.4 95.0 0.49 0.6944 1.0 1971688 ChemDiv1_002848 OC(=O)c1ccc(COc2ccc(C=C3C(=O)NC(=S)NC3=O)cc2Br)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B11 compound treatment 286.5 94.2 0.49 284.9 97.5 0.51 0.7058 0.9999 1971689 ChemDiv1_002849 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B12 compound treatment 285.3 93.0 0.49 270.4 83.0 0.43 0.6481 0.9983 1945511 ChemDiv1_002850 Cc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(Br)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B13 compound treatment 280.7 88.4 0.46 285.9 98.5 0.51 0.6881 0.9987 1971690 ChemDiv1_002851 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(O)c(OC)c4)C(=O)OCCOc5ccccc5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B14 compound treatment 282.4 90.1 0.47 284.7 97.3 0.51 0.6899 0.9993 1971691 ChemDiv1_002852 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B15 compound treatment 284.0 91.7 0.48 285.0 97.6 0.51 0.6969 0.9996 1266671 ChemDiv1_002853 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B16 compound treatment 281.9 89.6 0.47 278.9 91.5 0.48 0.6668 1.0 1971692 ChemDiv1_002854 CCCOc1ccc(OCCSc2nc3ccccc3n2CC(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B17 compound treatment 284.7 92.4 0.48 282.5 95.1 0.49 0.6903 0.9999 1546931 ChemDiv1_002855 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccs2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B18 compound treatment 280.2 87.9 0.46 281.3 93.9 0.49 0.6693 0.9995 1684044 ChemDiv1_002856 O=C(On1c(nc2ccccc2c1=O)c3ccccc3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B19 compound treatment 283.5 91.2 0.48 276.8 89.4 0.46 0.6649 0.9999 1199419 ChemDiv1_002857 COC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B20 compound treatment 289.2 96.9 0.51 278.8 91.4 0.47 0.6933 0.9995 1187744 ChemDiv1_002858 Clc1nc(NCc2ccco2)nc(Nc3nc(cs3)c4ccccc4)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B21 compound treatment 277.7 85.4 0.45 281.8 94.4 0.49 0.6619 0.9989 1943418 ChemDiv1_002859 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B22 compound treatment 277.9 85.6 0.45 278.6 91.2 0.47 0.6509 0.9996 1468275 ChemDiv1_002860 COc1ccccc1NC2CC(C)N(C(=O)c3ccc(C)cc3)c4c(C)cccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B23 mock treatment 283.4 91.1 0.48 280.9 93.5 0.49 0.6796 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 B24 mock treatment 82.4 -110.0 -0.57 82.8 -105.0 -0.54 -0.7899 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C01 compound treatment 287.1 94.8 0.49 289.3 102.0 0.53 0.7242 0.9994 1493276 ChemDiv1_002861 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)Cc3ccccc3)c4ccccc4c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C02 compound treatment 286.5 94.2 0.49 287.7 100.0 0.52 0.7161 0.9996 1971693 ChemDiv1_002862 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C03 compound treatment 286.0 93.7 0.49 282.5 95.1 0.49 0.6951 1.0 1971694 ChemDiv1_002863 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C04 compound treatment 287.5 95.2 0.5 286.0 98.6 0.51 0.7135 0.9999 1971695 ChemDiv1_002864 COc1ccccc1NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccccc4)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C05 compound treatment 285.3 93.0 0.49 287.5 100.0 0.52 0.7109 0.9994 1605374 ChemDiv1_002865 CCOc1ccc(cc1)n2c(C)c(C(=O)OC3CCCCC3)c4cc(OC)ccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C06 compound treatment 285.0 92.7 0.48 282.7 95.3 0.5 0.6922 0.9999 1971696 ChemDiv1_002866 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C07 compound treatment 283.7 91.4 0.48 275.6 88.2 0.46 0.6613 0.9998 1971697 ChemDiv1_002867 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc(OC)cc3)C(=O)Nc4ccccc4OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C08 compound treatment 285.1 92.8 0.48 281.8 94.4 0.49 0.6892 1.0 1971698 ChemDiv1_002868 OC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccc(F)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C09 compound treatment 282.8 90.5 0.47 284.7 97.3 0.51 0.6914 0.9994 1971699 ChemDiv1_002869 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C10 compound treatment 281.7 89.4 0.47 282.2 94.8 0.49 0.6781 0.9996 1971700 ChemDiv1_002870 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(F)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C11 compound treatment 283.3 91.0 0.47 282.9 95.5 0.5 0.6866 0.9998 1971701 ChemDiv1_002871 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(OC)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C12 compound treatment 278.5 86.2 0.45 283.6 96.2 0.5 0.6715 0.9986 1689943 ChemDiv1_002872 COC(=O)CN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C13 compound treatment 285.7 93.4 0.49 282.7 95.3 0.5 0.6947 1.0 1971702 ChemDiv1_002873 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccccc3Cl)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C14 compound treatment 282.2 89.9 0.47 279.9 92.5 0.48 0.6715 0.9999 1782850 ChemDiv1_002874 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4ccccc4[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C15 compound treatment 285.3 93.0 0.49 280.3 92.9 0.48 0.6844 1.0 1971703 ChemDiv1_002875 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(F)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C16 compound treatment 281.1 88.8 0.46 279.3 91.9 0.48 0.6653 0.9999 1971704 ChemDiv1_002876 CCN(CC)CCCN1C(=O)C2C(C3C2C4C=CC3C5C4C(=O)N(CCCN(CC)CC)C5=O)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C17 compound treatment 285.0 92.7 0.48 285.3 97.9 0.51 0.7017 0.9997 1971705 ChemDiv1_002877 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(Br)cc3)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C18 compound treatment 285.2 92.9 0.48 281.9 94.5 0.49 0.69 1.0 1441771 ChemDiv1_002878 CCOC(=O)CSc1nc2-c3ccccc3CC(CC)(C4CCCCC4)c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C19 compound treatment 284.4 92.1 0.48 279.4 92.0 0.48 0.6778 1.0 1971706 ChemDiv1_002879 CN/1C(=O)CC(S\C1=N\c2cccc(c2)C(F)(F)F)C(=O)Nc3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C20 compound treatment 282.0 89.7 0.47 282.4 95.0 0.49 0.68 0.9996 1971707 ChemDiv1_002880 Cc1c([N+](=O)[O-])c(nn1CC(=O)Nc2cc(Oc3cccnc3)cc(c2)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C21 compound treatment 283.0 90.7 0.47 281.2 93.8 0.49 0.6793 0.9999 1971708 ChemDiv1_002881 CN/1C(=O)CC(S\C1=N/c2ccc(Cl)c(c2)C(F)(F)F)C(=O)Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C22 compound treatment 282.1 89.8 0.47 278.4 91.0 0.47 0.6657 1.0 1971709 ChemDiv1_002882 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)Nc4ccc5OCOc5c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C23 mock treatment 286.1 93.8 0.49 280.1 92.7 0.48 0.6867 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 C24 mock treatment 81.4 -111.0 -0.58 79.6 -108.0 -0.56 -0.8054 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D01 compound treatment 289.2 96.9 0.51 285.7 98.3 0.51 0.7187 1.0 1971710 ChemDiv1_002883 CCOC(=O)c1c(NC(=O)c2cnn3c(cc(nc23)c4ccco4)C(F)(F)F)sc5CCCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D02 compound treatment 283.8 91.5 0.48 284.7 97.3 0.51 0.6951 0.9996 1971711 ChemDiv1_002884 CC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D03 compound treatment 283.1 90.8 0.47 289.4 102.0 0.53 0.7098 0.9984 1971712 ChemDiv1_002885 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4cccnc4Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D04 compound treatment 282.8 90.5 0.47 284.9 97.5 0.51 0.6921 0.9994 1214132 ChemDiv1_002886 COc1ccc2nc(NC(=O)CSc3nc4cc(C)ccc4[nH]3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D05 compound treatment 283.1 90.8 0.47 291.5 104.0 0.54 0.7175 0.9978 1971713 ChemDiv1_002887 Fc1ccc(CNC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D06 compound treatment 289.8 97.5 0.51 283.7 96.3 0.5 0.7135 1.0 1230343 ChemDiv1_002888 COc1ccc(CNC(=O)CSc2nc3cc(OC)ccc3[nH]2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D07 compound treatment 284.6 92.3 0.48 287.6 100.0 0.52 0.7087 0.9992 1971714 ChemDiv1_002889 COc1cc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D08 compound treatment 290.0 97.7 0.51 287.3 99.9 0.52 0.7275 1.0 1739426 ChemDiv1_002890 Cc1cc(C)c2oc(nc2c1)c3ccc(NC(=O)c4ccc5OCCOc5c4)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D09 compound treatment 285.2 92.9 0.48 284.8 97.4 0.51 0.7006 0.9998 1971715 ChemDiv1_002891 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCCn3ccnc3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D10 compound treatment 283.1 90.8 0.47 285.3 97.9 0.51 0.6947 0.9994 1945468 ChemDiv1_002892 CN1C(=O)NC(=O)/C(=C\c2ccc(OCc3ccc(cc3)C(=O)O)c(Br)c2)/C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D11 compound treatment 285.3 93.0 0.49 280.8 93.4 0.49 0.6863 1.0 1943239 ChemDiv1_002893 COCCNC(=O)c1nn2c(cc(nc2c1Cl)c3ccc(OC)c(OC)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D12 compound treatment 285.9 93.6 0.49 280.4 93.0 0.48 0.687 1.0 1945465 ChemDiv1_002894 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(Br)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D13 compound treatment 280.3 88.0 0.46 287.0 99.6 0.52 0.6906 0.9982 1971716 ChemDiv1_002895 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCCOc4ccccc4)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D14 compound treatment 282.7 90.4 0.47 284.4 97.0 0.5 0.6899 0.9995 1971717 ChemDiv1_002896 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Cl)C(=O)CC(C2)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D15 compound treatment 288.1 95.8 0.5 284.4 97.0 0.5 0.7098 1.0 1485964 ChemDiv1_002897 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D16 compound treatment 285.8 93.5 0.49 284.2 96.8 0.5 0.7006 0.9999 1784062 ChemDiv1_002898 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D17 compound treatment 281.7 89.4 0.47 285.6 98.2 0.51 0.6906 0.999 1971718 ChemDiv1_002899 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D18 compound treatment 283.4 91.1 0.48 284.2 96.8 0.5 0.6918 0.9996 1971719 ChemDiv1_002900 [O-][N+](=O)c1ccc(cc1)C(=O)CSc2nnc(o2)c3ccco3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D19 compound treatment 285.1 92.8 0.48 283.0 95.6 0.5 0.6936 0.9999 1326627 ChemDiv1_002901 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2COc3ccccc3O2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D20 compound treatment 282.0 89.7 0.47 280.5 93.1 0.48 0.673 0.9999 1279285 ChemDiv1_002902 C1CN(CCO1)c2nc(Nc3nc(cs3)c4ccccc4)nc(n2)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D21 compound treatment 279.7 87.4 0.46 280.9 93.5 0.49 0.666 0.9995 1971720 ChemDiv1_002903 CC(=O)N1N=C(CC1c2ccccc2F)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D22 compound treatment 281.9 89.6 0.47 279.4 92.0 0.48 0.6686 0.9999 1395832 ChemDiv1_002904 COc1ccc(cc1)C(=O)N2C(C)CC(Nc3ccc(C)cc3)c4ccc(C)cc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D23 mock treatment 283.1 90.8 0.47 281.2 93.8 0.49 0.6796 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 D24 mock treatment 81.6 -111.0 -0.58 80.9 -107.0 -0.55 -0.7999 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E01 compound treatment 290.3 98.0 0.51 292.0 105.0 0.54 0.7459 0.9995 1297496 ChemDiv1_002905 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)COc3ccccc3)c4ccccc4c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E02 compound treatment 282.9 90.6 0.47 285.5 98.1 0.51 0.6947 0.9993 1971721 ChemDiv1_002906 COc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E03 compound treatment 285.7 93.4 0.49 287.1 99.7 0.52 0.7109 0.9995 1971722 ChemDiv1_002907 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E04 compound treatment 284.9 92.6 0.48 286.6 99.2 0.52 0.7061 0.9995 1971723 ChemDiv1_002908 O=C(Nc1ccccc1)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E05 compound treatment 288.5 96.2 0.5 288.5 101.0 0.53 0.7264 0.9997 1708247 ChemDiv1_002909 COc1ccc(cc1)c2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E06 compound treatment 290.4 98.1 0.51 285.2 97.8 0.51 0.7213 1.0 1971724 ChemDiv1_002910 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc(OC)cc3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E07 compound treatment 286.4 94.1 0.49 286.8 99.4 0.52 0.7124 0.9997 1971725 ChemDiv1_002911 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E08 compound treatment 283.1 90.8 0.47 288.4 101.0 0.52 0.7061 0.9987 1971726 ChemDiv1_002912 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E09 compound treatment 286.0 93.7 0.49 286.0 98.6 0.51 0.708 0.9997 1971727 ChemDiv1_002913 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(cc5)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E10 compound treatment 283.5 91.2 0.48 291.6 104.0 0.54 0.7193 0.9979 1971728 ChemDiv1_002914 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(F)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E11 compound treatment 283.4 91.1 0.48 287.2 99.8 0.52 0.7028 0.9991 1971729 ChemDiv1_002915 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(C)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E12 compound treatment 283.9 91.6 0.48 283.6 96.2 0.5 0.6914 0.9998 1141939 ChemDiv1_002916 CN(C)c1nc(nc(n1)N(CCOc2ccccc2C)C#N)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E13 compound treatment 283.1 90.8 0.47 284.3 96.9 0.5 0.691 0.9995 1971730 ChemDiv1_002917 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(OCC)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E14 compound treatment 286.4 94.1 0.49 287.2 99.8 0.52 0.7139 0.9996 1714810 ChemDiv1_002918 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E15 compound treatment 287.1 94.8 0.49 285.6 98.2 0.51 0.7106 0.9999 1971731 ChemDiv1_002919 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccccc3OC)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E16 compound treatment 286.6 94.3 0.49 287.5 100.0 0.52 0.7157 0.9996 1971732 ChemDiv1_002920 COc1ccccc1N2C(=O)C3C(C4C3C5C=CC4C6C5C(=O)N(C6=O)c7ccccc7OC)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E17 compound treatment 283.6 91.3 0.48 285.6 98.2 0.51 0.6976 0.9994 1971733 ChemDiv1_002921 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(C)c(Cl)c3)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E18 compound treatment 285.3 93.0 0.49 281.0 93.6 0.49 0.687 1.0 1528170 ChemDiv1_002922 Cn1c(SCC(=O)N2CCOCC2)nc3n(C)c(=O)n(C)c(=O)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E19 compound treatment 287.3 95.0 0.5 281.5 94.1 0.49 0.6962 1.0 1971734 ChemDiv1_002923 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(cc3)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E20 compound treatment 281.7 89.4 0.47 283.4 96.0 0.5 0.6826 0.9994 1971735 ChemDiv1_002924 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)Nc4ccc(OC)cc4OC)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E21 compound treatment 283.5 91.2 0.48 278.6 91.2 0.47 0.6716 1.0 1971736 ChemDiv1_002925 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E22 compound treatment 284.7 92.4 0.48 282.5 95.1 0.49 0.6903 0.9999 1971737 ChemDiv1_002926 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)NCC4CCCO4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E23 mock treatment 286.3 94.0 0.49 276.7 89.3 0.46 0.6749 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 E24 mock treatment 79.7 -113.0 -0.59 76.3 -111.0 -0.58 -0.8238 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F01 compound treatment 289.5 97.2 0.51 284.8 97.4 0.51 0.7165 1.0 1971738 ChemDiv1_002927 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4cc(C)ccc4O)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F02 compound treatment 282.4 90.1 0.47 286.6 99.2 0.52 0.6969 0.9989 1206594 ChemDiv1_002928 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F03 compound treatment 282.2 89.9 0.47 285.8 98.4 0.51 0.6932 0.9991 1971739 ChemDiv1_002929 FC(F)(F)c1cc(nc2c(cnn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F04 compound treatment 283.3 91.0 0.47 282.0 94.6 0.49 0.6833 0.9999 1971740 ChemDiv1_002930 FC(F)(F)c1ccccc1NC(=O)CSc2nc3ccccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F05 compound treatment 286.4 94.1 0.49 288.5 101.0 0.53 0.7186 0.9994 1971741 ChemDiv1_002931 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)Nc3cccnc3Cl)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F06 compound treatment 289.9 97.6 0.51 290.3 103.0 0.53 0.7382 0.9997 1971742 ChemDiv1_002932 COc1cccc(NC(=O)CSc2nc3ccccc3n2C(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F07 compound treatment 283.4 91.1 0.48 285.9 98.5 0.51 0.698 0.9993 1971743 ChemDiv1_002933 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F08 compound treatment 287.3 95.0 0.5 287.1 99.7 0.52 0.7168 0.9998 1668404 ChemDiv1_002934 Fc1ccccc1c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F09 compound treatment 284.5 92.2 0.48 287.9 100.0 0.52 0.7094 0.9992 1971744 ChemDiv1_002935 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCN3CCOCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F10 compound treatment 286.6 94.3 0.49 287.3 99.9 0.52 0.715 0.9996 1971745 ChemDiv1_002936 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F11 compound treatment 287.9 95.6 0.5 289.2 102.0 0.53 0.7267 0.9996 1971746 ChemDiv1_002937 CCN(CC)CCCNC(=O)c1nn2c(cc(nc2c1Cl)c3ccc(OC)c(OC)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F12 compound treatment 283.4 91.1 0.48 283.5 96.1 0.5 0.6892 0.9997 1945437 ChemDiv1_002938 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F13 compound treatment 280.4 88.1 0.46 286.5 99.1 0.51 0.6892 0.9984 1938187 ChemDiv1_002939 COc1cccc(C2NC(=O)NC(=C2C(=O)OCCOc3ccccc3)C)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F14 compound treatment 286.4 94.1 0.49 286.0 98.6 0.51 0.7094 0.9998 1971747 ChemDiv1_002940 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F15 compound treatment 286.4 94.1 0.49 285.4 98.0 0.51 0.7072 0.9998 1716164 ChemDiv1_002941 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(F)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F16 compound treatment 283.3 91.0 0.47 284.6 97.2 0.51 0.6929 0.9995 1189094 ChemDiv1_002942 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F17 compound treatment 283.6 91.3 0.48 281.6 94.2 0.49 0.6829 0.9999 1971748 ChemDiv1_002943 CC1=C(C(C2=C(CC(CC2=O)c3ccc(Cl)cc3)N1)c4cccnc4)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F18 compound treatment 284.0 91.7 0.48 279.9 92.5 0.48 0.6782 1.0 1926772 ChemDiv1_002944 Brc1ccc(cc1)C(=O)CSc2nnc(o2)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F19 compound treatment 285.1 92.8 0.48 280.8 93.4 0.49 0.6855 1.0 1971749 ChemDiv1_002945 CC/N=C/1\SC(CC(=O)Nc2ccc(F)cc2)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F20 compound treatment 282.8 90.5 0.47 280.1 92.7 0.48 0.6745 1.0 1971750 ChemDiv1_002946 FC(F)(F)c1cccc(NC(=O)CSc2nc3ccccc3o2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F21 compound treatment 278.3 86.0 0.45 282.1 94.7 0.49 0.6652 0.9989 1928138 ChemDiv1_002947 OC(=O)CCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F22 compound treatment 280.7 88.4 0.46 277.1 89.7 0.47 0.6557 1.0 1447227 ChemDiv1_002948 CC1CC(Nc2ccc(C)cc2)c3ccc(C)cc3N1C(=O)c4cccc(F)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F23 mock treatment 285.4 93.1 0.49 282.8 95.4 0.5 0.694 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 F24 mock treatment 81.8 -110.0 -0.58 82.9 -105.0 -0.54 -0.7918 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G01 compound treatment 286.7 94.4 0.49 290.0 103.0 0.53 0.7253 0.9992 1240434 ChemDiv1_002949 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)COc3ccccc3C)c4ccccc4c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G02 compound treatment 286.8 94.5 0.49 287.6 100.0 0.52 0.7168 0.9996 1971751 ChemDiv1_002950 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G03 compound treatment 285.6 93.3 0.49 284.2 96.8 0.5 0.6999 0.9999 1409622 ChemDiv1_002951 O=C1CCC(=O)N1c2ccc(cc2)c3nc4sc5CCCc5c4c(=O)o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G04 compound treatment 284.4 92.1 0.48 283.0 95.6 0.5 0.691 0.9999 1971752 ChemDiv1_002952 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc(Cl)cc3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G05 compound treatment 289.8 97.5 0.51 286.3 98.9 0.51 0.7231 1.0 1172543 ChemDiv1_002953 CC1(C)Cc2c(sc3ncn4nc(nc4c23)c5ccccc5O)C(C)(C)N1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G06 compound treatment 282.1 89.8 0.47 287.9 100.0 0.52 0.7006 0.9985 1971753 ChemDiv1_002954 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G07 compound treatment 290.0 97.7 0.51 286.4 99.0 0.51 0.7242 1.0 1971754 ChemDiv1_002955 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccccc4OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G08 compound treatment 285.9 93.6 0.49 289.9 102.0 0.53 0.7219 0.9991 1971755 ChemDiv1_002956 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccc(cc4)C(=O)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G09 compound treatment 292.2 99.9 0.52 286.7 99.3 0.52 0.7334 1.0 1971756 ChemDiv1_002957 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(F)cc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G10 compound treatment 281.1 88.8 0.46 285.7 98.3 0.51 0.6888 0.9988 1971757 ChemDiv1_002958 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccc(Cl)cc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G11 compound treatment 286.1 93.8 0.49 285.1 97.7 0.51 0.705 0.9998 1971758 ChemDiv1_002959 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(Cl)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G12 compound treatment 286.0 93.7 0.49 285.4 98.0 0.51 0.7058 0.9998 1971759 ChemDiv1_002960 CCN(CC)C(=O)CN(C#N)c1nc(nc(n1)N(C)C)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G13 compound treatment 284.1 91.8 0.48 288.5 101.0 0.53 0.7102 0.9989 1971760 ChemDiv1_002961 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(cc3)C(=O)OCC)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G14 compound treatment 279.5 87.2 0.46 284.5 97.1 0.5 0.6785 0.9987 1228270 ChemDiv1_002962 CC(C)Sc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G15 compound treatment 288.4 96.1 0.5 284.2 96.8 0.5 0.7102 1.0 1971761 ChemDiv1_002963 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3cccc(F)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G16 compound treatment 284.4 92.1 0.48 282.5 95.1 0.49 0.6892 0.9999 1971762 ChemDiv1_002964 Oc1cccc(c1)N2C(=O)C3C(C4C3C5C=CC4C6C5C(=O)N(C6=O)c7cccc(O)c7)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G17 compound treatment 282.6 90.3 0.47 282.2 94.8 0.49 0.6815 0.9998 1971763 ChemDiv1_002965 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccccc3OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G18 compound treatment 279.6 87.3 0.46 283.3 95.9 0.5 0.6744 0.999 1546202 ChemDiv1_002966 COC(=O)c1ccccc1NC(=O)Cn2c(SC)nc3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G19 compound treatment 286.3 94.0 0.49 284.3 96.9 0.5 0.7028 0.9999 1971764 ChemDiv1_002967 CCOc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)c(Cl)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G20 compound treatment 285.2 92.9 0.48 281.8 94.4 0.49 0.6896 1.0 1928539 ChemDiv1_002968 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G21 compound treatment 288.1 95.8 0.5 283.3 95.9 0.5 0.7058 1.0 1971765 ChemDiv1_002969 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N\c5ccc(F)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G22 compound treatment 280.6 88.3 0.46 280.5 93.1 0.48 0.6678 0.9997 1971766 ChemDiv1_002970 COc1ccc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(OC)c(OC)c4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G23 mock treatment 284.8 92.5 0.48 276.5 89.1 0.46 0.6686 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 G24 mock treatment 79.7 -113.0 -0.59 79.6 -108.0 -0.56 -0.8116 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H01 compound treatment 286.9 94.6 0.49 286.5 99.1 0.51 0.7131 0.9998 1971767 ChemDiv1_002971 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4ccc(cc4)C(=O)C)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H02 compound treatment 287.4 95.1 0.5 283.5 96.1 0.5 0.7039 1.0 1971768 ChemDiv1_002972 Brc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4)C(=O)c5ccncc5)c(c6ccccc6)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H03 compound treatment 286.8 94.5 0.49 286.6 99.2 0.52 0.7131 0.9998 1971769 ChemDiv1_002973 COc1ccc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc5OCOc5c4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H04 compound treatment 288.3 96.0 0.5 285.4 98.0 0.51 0.7143 1.0 1971770 ChemDiv1_002974 CC(=O)c1ccc(NC(=O)CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H05 compound treatment 283.3 91.0 0.47 285.4 98.0 0.51 0.6958 0.9994 1971771 ChemDiv1_002975 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3nn4c(cc(nc4c3Cl)c5ccco5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H06 compound treatment 285.8 93.5 0.49 286.8 99.4 0.52 0.7102 0.9996 1971772 ChemDiv1_002976 CC1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H07 compound treatment 285.1 92.8 0.48 285.7 98.3 0.51 0.7035 0.9996 1971773 ChemDiv1_002977 COc1cc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H08 compound treatment 285.1 92.8 0.48 288.8 101.0 0.53 0.7149 0.9991 1532693 ChemDiv1_002978 COc1ccc(cc1)n2nc3ccc(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H09 compound treatment 286.1 93.8 0.49 287.0 99.6 0.52 0.712 0.9996 1971774 ChemDiv1_002979 COc1ccc(cc1OC)c2cc(n3nc(C(=O)N4CCN(C)CC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H10 compound treatment 281.4 89.1 0.46 285.8 98.4 0.51 0.6903 0.9989 1945601 ChemDiv1_002980 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H11 compound treatment 287.0 94.7 0.49 288.5 101.0 0.53 0.7208 0.9995 1399164 ChemDiv1_002981 O=C(Nc1ccc(cc1)c2nc3ncccc3o2)c4ccc5CCc6cccc4c65 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H12 compound treatment 282.9 90.6 0.47 288.5 101.0 0.53 0.7057 0.9986 1971775 ChemDiv1_002982 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H13 compound treatment 284.4 92.1 0.48 286.6 99.2 0.52 0.7043 0.9994 1327648 ChemDiv1_002983 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H14 compound treatment 282.6 90.3 0.47 285.6 98.2 0.51 0.694 0.9992 1971776 ChemDiv1_002984 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H15 compound treatment 285.6 93.3 0.49 282.4 95.0 0.49 0.6933 1.0 1784055 ChemDiv1_002985 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H16 compound treatment 288.6 96.3 0.5 288.1 101.0 0.52 0.7253 0.9998 1726949 ChemDiv1_002986 CCOC(=O)c1c(CN2CCC(C)CC2)n(C)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H17 compound treatment 283.4 91.1 0.48 293.9 106.0 0.55 0.7274 0.9971 1340179 ChemDiv1_002987 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cc(OC)c(OC)c(OC)c4)C(=O)OCC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H18 compound treatment 285.6 93.3 0.49 280.5 93.1 0.48 0.6863 1.0 1938496 ChemDiv1_002988 COc1ccc(Nc2nc(Nc3ccc(cc3)[N+](=O)[O-])nc(OC)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H19 compound treatment 283.0 90.7 0.47 284.0 96.6 0.5 0.6896 0.9996 1950508 ChemDiv1_002989 CC/N=C/1\SC(CC(=O)Nc2ccccc2C#N)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H20 compound treatment 282.5 90.2 0.47 284.8 97.4 0.51 0.6907 0.9993 1971777 ChemDiv1_002990 Cc1ccc2[nH]c(SCC(=O)Nc3cccc(c3)C(F)(F)F)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H21 compound treatment 283.9 91.6 0.48 280.7 93.3 0.48 0.6807 1.0 1971778 ChemDiv1_002991 COc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H22 compound treatment 282.6 90.3 0.47 278.6 91.2 0.47 0.6682 1.0 1344202 ChemDiv1_002992 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)COc4ccc5ccccc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H23 mock treatment 284.1 91.8 0.48 281.5 94.1 0.49 0.6844 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 H24 mock treatment 80.7 -112.0 -0.58 78.8 -109.0 -0.56 -0.8109 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I01 compound treatment 286.8 94.5 0.49 286.8 99.4 0.52 0.7139 0.9997 1971779 ChemDiv1_002993 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3cccc4ccccc34)c5ccccc5c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I02 compound treatment 286.6 94.3 0.49 286.9 99.5 0.52 0.7135 0.9997 1971780 ChemDiv1_002994 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccccc4OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I03 compound treatment 286.2 93.9 0.49 285.0 97.6 0.51 0.705 0.9999 1277715 ChemDiv1_002995 Cc1sc2nc(oc(=O)c2c1C)c3ccc(cc3)N4C(=O)CCC4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I04 compound treatment 285.6 93.3 0.49 287.6 100.0 0.52 0.7124 0.9994 1971781 ChemDiv1_002996 COC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I05 compound treatment 287.7 95.4 0.5 290.3 103.0 0.53 0.73 0.9994 1210048 ChemDiv1_002997 COc1ccc(cc1OC)c2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I06 compound treatment 288.3 96.0 0.5 289.4 102.0 0.53 0.729 0.9996 1971782 ChemDiv1_002998 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccccc4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I07 compound treatment 288.1 95.8 0.5 287.4 100.0 0.52 0.7209 0.9998 1971783 ChemDiv1_002999 COc1ccccc1NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(F)cc5)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I08 compound treatment 286.9 94.6 0.49 290.4 103.0 0.54 0.7275 0.9992 1971784 ChemDiv1_003000 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I09 compound treatment 286.6 94.3 0.49 287.4 100.0 0.52 0.7153 0.9996 1971785 ChemDiv1_003001 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I10 compound treatment 280.4 88.1 0.46 284.7 97.3 0.51 0.6825 0.9989 1971786 ChemDiv1_003002 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(Cl)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I11 compound treatment 283.8 91.5 0.48 289.3 102.0 0.53 0.712 0.9987 1971787 ChemDiv1_003003 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(F)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I12 compound treatment 281.2 88.9 0.46 282.6 95.2 0.49 0.6778 0.9995 1293063 ChemDiv1_003004 COc1ccccc1OCCN(C#N)c2nc(nc(n2)N(C)C)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I13 compound treatment 283.8 91.5 0.48 289.5 102.0 0.53 0.7127 0.9986 1971788 ChemDiv1_003005 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)c(Cl)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I14 compound treatment 284.7 92.4 0.48 283.7 96.3 0.5 0.6947 0.9998 1642630 ChemDiv1_003006 CN1Cc2c(nc3sc(C(=O)c4ccccc4)c(N)c3c2CC1(C)C)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I15 compound treatment 283.7 91.4 0.48 286.2 98.8 0.51 0.7002 0.9993 1971789 ChemDiv1_003007 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3cccc(c3)C(F)(F)F)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I16 compound treatment 284.0 91.7 0.48 286.5 99.1 0.51 0.7024 0.9993 1971790 ChemDiv1_003008 Oc1ccc(cc1)N2C(=O)C3C(C4C3C5C=CC4C6C5C(=O)N(C6=O)c7ccc(O)cc7)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I17 compound treatment 286.4 94.1 0.49 288.6 101.0 0.53 0.719 0.9994 1971791 ChemDiv1_003009 COc1ccccc1NC(=O)C2CC(=O)N(C)/C(=N\c3cccc(c3)C(F)(F)F)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I18 compound treatment 286.8 94.5 0.49 283.0 95.6 0.5 0.6999 1.0 1170886 ChemDiv1_003010 COC(=O)c1ccccc1NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I19 compound treatment 282.2 89.9 0.47 281.8 94.4 0.49 0.6785 0.9998 1971792 ChemDiv1_003011 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)c(Cl)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I20 compound treatment 279.7 87.4 0.46 281.0 93.6 0.49 0.6664 0.9995 1971793 ChemDiv1_003012 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)NCCCn3ccnc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I21 compound treatment 288.7 96.4 0.5 287.3 99.9 0.52 0.7227 0.9999 1971794 ChemDiv1_003013 Fc1ccc(/N=C\2/SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I22 compound treatment 284.0 91.7 0.48 280.3 92.9 0.48 0.6796 1.0 1971795 ChemDiv1_003014 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)Nc4cccc(c4)C(=O)C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I23 mock treatment 287.4 95.1 0.5 282.8 95.4 0.5 0.7014 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 I24 mock treatment 82.2 -110.0 -0.57 79.0 -108.0 -0.56 -0.8046 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J01 compound treatment 287.1 94.8 0.49 284.6 97.2 0.51 0.7069 0.9999 1971796 ChemDiv1_003015 COc1ccc(NC(=O)c2cnn3c(cc(nc23)c4cc(OC)c(OC)c(OC)c4)C(F)(F)F)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J02 compound treatment 287.3 95.0 0.5 284.8 97.4 0.51 0.7084 0.9999 1971797 ChemDiv1_003016 Brc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4)C(=O)c5cccnc5)c(c6ccccc6)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J03 compound treatment 287.3 95.0 0.5 284.9 97.5 0.51 0.7087 0.9999 1971798 ChemDiv1_003017 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCCN3CCOCC3)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J04 compound treatment 287.9 95.6 0.5 286.1 98.7 0.51 0.7153 0.9999 1971799 ChemDiv1_003018 COc1ccc2nc(NC(=O)CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J05 compound treatment 282.5 90.2 0.47 284.6 97.2 0.51 0.6899 0.9994 1943197 ChemDiv1_003019 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J06 compound treatment 286.9 94.6 0.49 287.4 100.0 0.52 0.7164 0.9997 1634373 ChemDiv1_003020 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J07 compound treatment 284.8 92.5 0.48 286.8 99.4 0.52 0.7065 0.9994 1943209 ChemDiv1_003021 COc1ccc(cc1)c2cc(n3nc(C(=O)N4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J08 compound treatment 286.1 93.8 0.49 285.1 97.7 0.51 0.705 0.9998 1396140 ChemDiv1_003022 Cc1ccc(cc1Cl)n2nc3ccc(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J09 compound treatment 288.7 96.4 0.5 283.8 96.4 0.5 0.7098 1.0 1971800 ChemDiv1_003023 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J10 compound treatment 283.6 91.3 0.48 285.4 98.0 0.51 0.6969 0.9994 1945399 ChemDiv1_003024 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J11 compound treatment 281.7 89.4 0.47 285.0 97.6 0.51 0.6884 0.9991 1232011 ChemDiv1_003025 COc1ccc(cc1)c2nc3cc(NC(=O)c4cc5ccccc5cc4OC)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J12 compound treatment 286.6 94.3 0.49 286.5 99.1 0.51 0.712 0.9997 1945392 ChemDiv1_003026 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(Br)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J13 compound treatment 284.8 92.5 0.48 285.8 98.4 0.51 0.7028 0.9996 1623161 ChemDiv1_003027 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J14 compound treatment 286.7 94.4 0.49 284.2 96.8 0.5 0.7039 0.9999 1971801 ChemDiv1_003028 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J15 compound treatment 284.5 92.2 0.48 282.9 95.5 0.5 0.691 0.9999 1971802 ChemDiv1_003029 CCOC(=O)C(C)OC(=O)C1=C(C)NC(=O)NC1c2cc(OC)c(OC)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J16 compound treatment 286.9 94.6 0.49 284.1 96.7 0.5 0.7043 1.0 1971803 ChemDiv1_003030 CCOC(=O)c1c(CN2CCC(CC2)(C(=O)OCC)c3ccccc3)n(c4ccccc4)c5cc(Br)c(O)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J17 compound treatment 285.8 93.5 0.49 285.4 98.0 0.51 0.705 0.9998 1971804 ChemDiv1_003031 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(OC(=O)C)c(OC)c4)C(=O)OCCOc5ccccc5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J18 compound treatment 283.1 90.8 0.47 283.5 96.1 0.5 0.6881 0.9997 1300591 ChemDiv1_003032 COc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J19 compound treatment 285.5 93.2 0.49 282.8 95.4 0.5 0.6944 1.0 1946093 ChemDiv1_003033 CCc1ccc(/C=C\2/SC(=S)N(CCC(=O)O)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J20 compound treatment 285.6 93.3 0.49 279.8 92.4 0.48 0.6837 1.0 1971805 ChemDiv1_003034 O=C(CSc1nc2ccccc2o1)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J21 compound treatment 289.9 97.6 0.51 288.3 101.0 0.52 0.7308 0.9999 1592777 ChemDiv1_003035 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J22 compound treatment 284.0 91.7 0.48 279.4 92.0 0.48 0.6763 1.0 1711243 ChemDiv1_003036 Cn1cnnc1SCC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J23 mock treatment 284.4 92.1 0.48 282.3 94.9 0.49 0.6885 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 J24 mock treatment 80.6 -112.0 -0.58 75.5 -112.0 -0.58 -0.8234 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K01 compound treatment 284.3 92.0 0.48 282.7 95.3 0.5 0.6896 0.9999 1971806 ChemDiv1_003037 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3cccc(c3)[N+](=O)[O-])c4ccccc4c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K02 compound treatment 288.1 95.8 0.5 287.5 100.0 0.52 0.7212 0.9998 1971807 ChemDiv1_003038 Fc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K03 compound treatment 288.8 96.5 0.5 289.7 102.0 0.53 0.7319 0.9996 1672455 ChemDiv1_003039 O=C1CCC(=O)N1c2ccc(cc2)c3nc4scc(c5cccs5)c4c(=O)o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K04 compound treatment 283.8 91.5 0.48 285.0 97.6 0.51 0.6962 0.9995 1971808 ChemDiv1_003040 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K05 compound treatment 285.3 93.0 0.49 288.8 101.0 0.53 0.7157 0.9992 1474583 ChemDiv1_003041 COc1ccc(Cc2nc3c4c5CCCCc5sc4ncn3n2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K06 compound treatment 285.9 93.6 0.49 283.1 95.7 0.5 0.6969 1.0 1971809 ChemDiv1_003042 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K07 compound treatment 283.7 91.4 0.48 288.2 101.0 0.52 0.7076 0.9989 1971810 ChemDiv1_003043 Fc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)NCCc5ccccc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K08 compound treatment 284.5 92.2 0.48 284.4 97.0 0.5 0.6966 0.9997 1971811 ChemDiv1_003044 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cccc(c3)C(F)(F)F)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K09 compound treatment 288.1 95.8 0.5 284.8 97.4 0.51 0.7113 1.0 1971812 ChemDiv1_003045 CCOc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K10 compound treatment 284.5 92.2 0.48 291.5 104.0 0.54 0.7227 0.9983 1971813 ChemDiv1_003046 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(cc5)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K11 compound treatment 287.8 95.5 0.5 285.9 98.5 0.51 0.7142 0.9999 1971814 ChemDiv1_003047 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccccc3OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K12 compound treatment 281.1 88.8 0.46 286.2 98.8 0.51 0.6906 0.9987 1711103 ChemDiv1_003048 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(C#N)c2nc(C)cc(C)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K13 compound treatment 284.4 92.1 0.48 284.6 97.2 0.51 0.6969 0.9997 1971815 ChemDiv1_003049 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)NCCc3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K14 compound treatment 283.6 91.3 0.48 283.8 96.4 0.5 0.691 0.9997 1562270 ChemDiv1_003050 CC(=C)CSc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K15 compound treatment 282.5 90.2 0.47 287.8 100.0 0.52 0.7017 0.9987 1971816 ChemDiv1_003051 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(C)c(C)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K16 compound treatment 282.2 89.9 0.47 285.4 98.0 0.51 0.6917 0.9992 1163881 ChemDiv1_003052 COc1ccc(cc1)n2c(SCC#N)nc3sc4CCCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K17 compound treatment 286.8 94.5 0.49 283.4 96.0 0.5 0.7014 1.0 1971817 ChemDiv1_003053 CCOc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(Cl)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K18 compound treatment 284.1 91.8 0.48 283.0 95.6 0.5 0.6899 0.9998 1776162 ChemDiv1_003054 Cc1c(Br)c(nn1CC(=O)N2CCN(Cc3ccccc3)CC2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K19 compound treatment 288.3 96.0 0.5 281.4 94.0 0.49 0.6995 0.9999 1971818 ChemDiv1_003055 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(F)cc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K20 compound treatment 287.9 95.6 0.5 283.3 95.9 0.5 0.7051 1.0 1483873 ChemDiv1_003056 CCOc1ccc(cc1)c2cc(C)n3nc(cc3n2)C(=O)Nc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K21 compound treatment 289.0 96.7 0.5 283.1 95.7 0.5 0.7084 1.0 1971819 ChemDiv1_003057 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(F)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K22 compound treatment 286.4 94.1 0.49 280.3 92.9 0.48 0.6885 1.0 1971820 ChemDiv1_003058 COc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(OC)c(OC)c4)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K23 mock treatment 288.5 96.2 0.5 283.1 95.7 0.5 0.7065 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 K24 mock treatment 80.5 -112.0 -0.58 80.0 -107.0 -0.56 -0.8072 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L01 compound treatment 288.9 96.6 0.5 285.9 98.5 0.51 0.7183 1.0 1971821 ChemDiv1_003059 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4ccc(O)cc4)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L02 compound treatment 299.5 107.0 0.56 296.2 109.0 0.57 0.7953 1.0 1694032 ChemDiv1_003060 COc1ccccc1C2CC(=NN2C(=O)c3ccco3)c4c(c5ccccc5)c6cc(Br)ccc6[nH]c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L03 compound treatment 288.6 96.3 0.5 284.1 96.7 0.5 0.7106 1.0 1971822 ChemDiv1_003061 Cc1c(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc5OCOc5c4)c(=O)n(c6ccccc6)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L04 compound treatment 285.5 93.2 0.49 285.5 98.1 0.51 0.7043 0.9997 1971823 ChemDiv1_003062 COc1ccc(CNC(=O)CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L05 compound treatment 286.2 93.9 0.49 286.3 98.9 0.51 0.7098 0.9997 1971824 ChemDiv1_003063 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCCn3ccnc3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L06 compound treatment 287.0 94.7 0.49 286.1 98.7 0.51 0.712 0.9998 1147098 ChemDiv1_003064 Cc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc5OCCOc5c4)cc3O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L07 compound treatment 289.5 97.2 0.51 285.1 97.7 0.51 0.7176 1.0 1943146 ChemDiv1_003065 COc1ccc(cc1)c2cc(n3nc(C(=O)NCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L08 compound treatment 287.6 95.3 0.5 286.2 98.8 0.51 0.7146 0.9999 1522461 ChemDiv1_003066 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L09 compound treatment 284.5 92.2 0.48 285.2 97.8 0.51 0.6995 0.9996 1971825 ChemDiv1_003067 COc1ccc(cc1OC)c2cc(n3nc(C(=O)N4CCSCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L10 compound treatment 281.9 89.6 0.47 283.6 96.2 0.5 0.684 0.9994 1971826 ChemDiv1_003068 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L11 compound treatment 287.8 95.5 0.5 288.2 101.0 0.52 0.7227 0.9997 1780660 ChemDiv1_003069 Oc1cc(NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])ccc1c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L12 compound treatment 286.6 94.3 0.49 287.0 99.6 0.52 0.7139 0.9997 1207581 ChemDiv1_003070 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L13 compound treatment 284.9 92.6 0.48 285.2 97.8 0.51 0.701 0.9997 1971827 ChemDiv1_003071 CN1C(=C(C(NC1=O)c2ccc(Br)s2)C(=O)OCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L14 compound treatment 283.1 90.8 0.47 287.5 100.0 0.52 0.7028 0.9989 1971828 ChemDiv1_003072 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L15 compound treatment 288.3 96.0 0.5 282.4 95.0 0.49 0.7032 1.0 1568329 ChemDiv1_003073 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L16 compound treatment 287.0 94.7 0.49 284.2 96.8 0.5 0.705 1.0 1570991 ChemDiv1_003074 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(C)c4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L17 compound treatment 282.4 90.1 0.47 282.8 95.4 0.5 0.6829 0.9997 1496075 ChemDiv1_003075 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(OC)c(OC)c4)C(=O)OCC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L18 compound treatment 294.2 102.0 0.53 287.0 99.6 0.52 0.7419 0.9999 1305028 ChemDiv1_003076 COc1ccc(Nc2nc(Cl)nc(NCc3ccco3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L19 compound treatment 284.3 92.0 0.48 283.8 96.4 0.5 0.6936 0.9998 1971829 ChemDiv1_003077 COc1ccccc1C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L20 compound treatment 282.9 90.6 0.47 280.9 93.5 0.49 0.6778 0.9999 1971830 ChemDiv1_003078 O=C1C2C(C3C2C4C=CC3C5C4C(=O)N(C6CCCCC6)C5=O)C(=O)N1C7CCCCC7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L21 compound treatment 283.1 90.8 0.47 278.3 90.9 0.47 0.669 1.0 1971831 ChemDiv1_003079 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L22 compound treatment 286.1 93.8 0.49 279.5 92.1 0.48 0.6844 0.9999 1971832 ChemDiv1_003080 CC1(CN2CC3(C)CN(C1)C24C(=O)Nc5ccccc54)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L23 mock treatment 281.6 89.3 0.47 284.3 96.9 0.5 0.6855 0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 L24 mock treatment 80.4 -112.0 -0.58 75.8 -112.0 -0.58 -0.823 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M01 compound treatment 286.9 94.6 0.49 286.9 99.5 0.52 0.7146 0.9997 1971833 ChemDiv1_003081 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3cccc(Cl)c3)c4ccccc4c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M02 compound treatment 287.5 95.2 0.5 284.2 96.8 0.5 0.7069 1.0 1971834 ChemDiv1_003082 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(OC)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M03 compound treatment 287.4 95.1 0.5 286.5 99.1 0.51 0.715 0.9998 1971835 ChemDiv1_003083 COc1ccc(/C=C/c2nc3scc(c4cccs4)c3c(=O)o2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M04 compound treatment 284.2 91.9 0.48 282.2 94.8 0.49 0.6874 0.9999 1971836 ChemDiv1_003084 COc1ccccc1NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccccc4)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M05 compound treatment 289.2 96.9 0.51 287.4 100.0 0.52 0.7249 0.9999 1262178 ChemDiv1_003085 COc1ccc(Cc2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M06 compound treatment 282.5 90.2 0.47 282.3 94.9 0.49 0.6815 0.9997 1971837 ChemDiv1_003086 CN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M07 compound treatment 286.1 93.8 0.49 289.1 102.0 0.53 0.7197 0.9993 1971838 ChemDiv1_003087 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc(OC)cc3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M08 compound treatment 290.4 98.1 0.51 282.2 94.8 0.49 0.7102 0.9998 1971839 ChemDiv1_003088 OC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M09 compound treatment 285.4 93.1 0.49 285.1 97.7 0.51 0.7025 0.9998 1971840 ChemDiv1_003089 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)NCCc5ccccc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M10 compound treatment 284.5 92.2 0.48 284.2 96.8 0.5 0.6958 0.9998 1971841 ChemDiv1_003090 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M11 compound treatment 290.0 97.7 0.51 284.0 96.6 0.5 0.7154 1.0 1971842 ChemDiv1_003091 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(OCC)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M12 compound treatment 286.9 94.6 0.49 278.7 91.3 0.47 0.6845 0.9998 1714667 ChemDiv1_003092 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M13 compound treatment 283.9 91.6 0.48 285.8 98.4 0.51 0.6995 0.9994 1971843 ChemDiv1_003093 CN/1C(=O)CC(S\C1=N\c2cccc(c2)C(F)(F)F)C(=O)NCCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M14 compound treatment 292.3 100.0 0.52 285.8 98.4 0.51 0.7305 0.9999 1413010 ChemDiv1_003094 COC(=O)c1ccc(o1)c2sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M15 compound treatment 283.6 91.3 0.48 285.6 98.2 0.51 0.6976 0.9994 1971844 ChemDiv1_003095 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(C)c(Cl)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M16 compound treatment 282.8 90.5 0.47 282.3 94.9 0.49 0.6826 0.9998 1971845 ChemDiv1_003096 CCNc1nc(NCC)nc(OCCNC(=O)COc2ccc(Cl)cc2Cl)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M17 compound treatment 280.7 88.4 0.46 285.6 98.2 0.51 0.687 0.9987 1971846 ChemDiv1_003097 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(Cl)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M18 compound treatment 284.4 92.1 0.48 282.0 94.6 0.49 0.6874 0.9999 1971847 ChemDiv1_003098 Cc1cc(nn1CC(=O)Nc2cc(Oc3cccnc3)cc(c2)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M19 compound treatment 286.4 94.1 0.49 281.8 94.4 0.49 0.694 1.0 1971848 ChemDiv1_003099 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(cc5)C(=O)OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M20 compound treatment 286.2 93.9 0.49 279.0 91.6 0.48 0.683 0.9999 1253275 ChemDiv1_003100 CCOc1ccc(cc1)c2cc(C)n3nc(cc3n2)C(=O)Nc4cc(OC)c(Cl)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M21 compound treatment 280.0 87.7 0.46 282.3 94.9 0.49 0.6722 0.9993 1971849 ChemDiv1_003101 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(Cl)cc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M22 compound treatment 285.3 93.0 0.49 277.7 90.3 0.47 0.6749 0.9999 1971850 ChemDiv1_003102 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)Nc4ccc(cc4)C(=O)C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M23 mock treatment 284.8 92.5 0.48 279.2 91.8 0.48 0.6786 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 M24 mock treatment 209.0 16.7 0.09 169.1 -18.3 -0.1 -0.0057 -0.0443 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N01 compound treatment 282.2 89.9 0.47 286.3 98.9 0.51 0.6951 0.999 1971851 ChemDiv1_003103 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)NCc4cccs4)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N02 compound treatment 288.5 96.2 0.5 284.9 97.5 0.51 0.7132 1.0 1971852 ChemDiv1_003104 FC(F)(F)c1ccccc1NC(=O)CSc2nc3ccccc3[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N03 compound treatment 288.0 95.7 0.5 286.5 99.1 0.51 0.7172 0.9999 1971853 ChemDiv1_003105 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N04 compound treatment 283.5 91.2 0.48 283.0 95.6 0.5 0.6877 0.9998 1650975 ChemDiv1_003106 CCOc1ccc2nc(SCC(=O)Nc3ccccc3C(=O)N)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N05 compound treatment 285.9 93.6 0.49 285.2 97.8 0.51 0.7047 0.9998 1971854 ChemDiv1_003107 COc1ccc(CNC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N06 compound treatment 286.2 93.9 0.49 287.3 99.9 0.52 0.7135 0.9996 1328501 ChemDiv1_003108 CCOc1ccc2nc(NC(=O)c3ccc4OCCOc4c3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N07 compound treatment 285.7 93.4 0.49 283.4 96.0 0.5 0.6973 0.9999 1943244 ChemDiv1_003109 CN1CCN(CC1)C(=O)c2nn3c(cc(nc3c2Cl)c4ccc(Cl)cc4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N08 compound treatment 289.5 97.2 0.51 286.6 99.2 0.52 0.7231 1.0 1382091 ChemDiv1_003110 COc1cc(OC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4ccc(OC)c(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N09 compound treatment 285.8 93.5 0.49 285.8 98.4 0.51 0.7065 0.9997 1971855 ChemDiv1_003111 COc1ccc(cc1OC)c2cc(n3nc(C(=O)N4CCCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N10 compound treatment 283.2 90.9 0.47 280.8 93.4 0.49 0.6785 0.9999 1945434 ChemDiv1_003112 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N11 compound treatment 287.5 95.2 0.5 286.3 98.9 0.51 0.7146 0.9999 1971856 ChemDiv1_003113 [O-][N+](=O)c1ccc(COc2ccc(Br)cc2/C=C/3\NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N12 compound treatment 285.6 93.3 0.49 282.9 95.5 0.5 0.6951 1.0 1194306 ChemDiv1_003114 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2cccs2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N13 compound treatment 282.5 90.2 0.47 281.4 94.0 0.49 0.6782 0.9998 1204119 ChemDiv1_003115 COc1cc(cc(OC)c1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N14 compound treatment 283.5 91.2 0.48 284.2 96.8 0.5 0.6921 0.9996 1971857 ChemDiv1_003116 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N15 compound treatment 283.0 90.7 0.47 280.4 93.0 0.48 0.6763 0.9999 1784056 ChemDiv1_003117 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N16 compound treatment 286.4 94.1 0.49 281.7 94.3 0.49 0.6936 1.0 1137308 ChemDiv1_003118 CCOC(=O)c1c(CN2CCN(Cc3ccccc3)CC2)n(C)c4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N17 compound treatment 288.7 96.4 0.5 277.3 89.9 0.47 0.686 0.9993 1864258 ChemDiv1_003119 COC(=O)c1c(NC(=O)CCN2C(=O)c3cccc([N+](=O)[O-])c3C2=O)sc4CC(C)CCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N18 compound treatment 281.5 89.2 0.47 281.7 94.3 0.49 0.6756 0.9997 1566688 ChemDiv1_003120 C(Nc1nc(nc(n1)N2CCOCC2)N3CCOCC3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N19 compound treatment 283.8 91.5 0.48 281.8 94.4 0.49 0.6844 0.9999 1646510 ChemDiv1_003121 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N20 compound treatment 282.6 90.3 0.47 277.8 90.4 0.47 0.6653 1.0 1971858 ChemDiv1_003122 O=C1C2C(C3C2C4C=CC3C5C4C(=O)N(C5=O)c6ccccn6)C(=O)N1c7ccccn7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N21 compound treatment 285.7 93.4 0.49 285.1 97.7 0.51 0.7036 0.9998 1971859 ChemDiv1_003123 COc1ccccc1C2CC(=NN2C(=O)C)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N22 compound treatment 282.9 90.6 0.47 282.8 95.4 0.5 0.6848 0.9997 1971860 ChemDiv1_003124 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N23 mock treatment 283.0 90.7 0.47 279.4 92.0 0.48 0.6726 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 N24 mock treatment 206.5 14.2 0.07 195.1 7.66 0.04 0.0806 0.9573 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O01 compound treatment 288.3 96.0 0.5 284.7 97.3 0.51 0.7117 1.0 1616099 ChemDiv1_003125 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3ccccc3F)c4ccccc4c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O02 compound treatment 288.4 96.1 0.5 282.9 95.5 0.5 0.7054 1.0 1971861 ChemDiv1_003126 COc1ccccc1NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O03 compound treatment 290.2 97.9 0.51 282.2 94.8 0.49 0.7095 0.9998 1944231 ChemDiv1_003127 COc1ccc(/C=C/c2nc3sc4CCCCc4c3c(=O)o2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O04 compound treatment 284.3 92.0 0.48 285.4 98.0 0.51 0.6995 0.9996 1971862 ChemDiv1_003128 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O05 compound treatment 283.9 91.6 0.48 282.7 95.3 0.5 0.6881 0.9998 1209043 ChemDiv1_003129 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc4OCOc4cc3Br)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O06 compound treatment 281.2 88.9 0.46 279.2 91.8 0.48 0.6653 0.9999 1971863 ChemDiv1_003130 COC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc4OCOc4c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O07 compound treatment 286.1 93.8 0.49 285.5 98.1 0.51 0.7065 0.9998 1971864 ChemDiv1_003131 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O08 compound treatment 284.7 92.4 0.48 285.6 98.2 0.51 0.7017 0.9996 1971865 ChemDiv1_003132 CCOc1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccc(cc3)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O09 compound treatment 291.1 98.8 0.52 282.0 94.6 0.49 0.7121 0.9997 1971866 ChemDiv1_003133 CCOc1cccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O10 compound treatment 286.0 93.7 0.49 285.7 98.3 0.51 0.7069 0.9998 1971867 ChemDiv1_003134 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O11 compound treatment 284.3 92.0 0.48 283.2 95.8 0.5 0.6914 0.9998 1971868 ChemDiv1_003135 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)NCCc3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O12 compound treatment 285.3 93.0 0.49 285.9 98.5 0.51 0.705 0.9996 1570697 ChemDiv1_003136 CCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O13 compound treatment 284.9 92.6 0.48 284.4 97.0 0.5 0.698 0.9998 1971869 ChemDiv1_003137 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(OC)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O14 compound treatment 285.8 93.5 0.49 285.9 98.5 0.51 0.7069 0.9997 1186933 ChemDiv1_003138 CN1C(=O)C(O)(C2COC(C)(C)CC2=O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O15 compound treatment 286.2 93.9 0.49 281.3 93.9 0.49 0.6914 1.0 1971870 ChemDiv1_003139 CCOc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(OCC)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O16 compound treatment 283.9 91.6 0.48 282.8 95.4 0.5 0.6885 0.9998 1971871 ChemDiv1_003140 CN(C)c1nc(nc(n1)N2CC(=O)N(C2=N)c3ccc(Cl)c(Cl)c3)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O17 compound treatment 284.4 92.1 0.48 279.3 91.9 0.48 0.6774 1.0 1971872 ChemDiv1_003141 CN/1C(=O)CC(S\C1=N\c2cccc(c2)C(F)(F)F)C(=O)Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O18 compound treatment 284.7 92.4 0.48 282.8 95.4 0.5 0.6914 0.9999 1971873 ChemDiv1_003142 COc1cc(NC(=O)Cn2nc(c(Br)c2C)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O19 compound treatment 282.1 89.8 0.47 278.4 91.0 0.47 0.6657 1.0 1971874 ChemDiv1_003143 CCOc1ccc(/N=C\2/SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O20 compound treatment 286.2 93.9 0.49 279.1 91.7 0.48 0.6833 0.9999 1971875 ChemDiv1_003144 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)NCc4ccco4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O21 compound treatment 283.6 91.3 0.48 279.0 91.6 0.48 0.6734 1.0 1971876 ChemDiv1_003145 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(F)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O22 compound treatment 282.7 90.4 0.47 281.9 94.5 0.49 0.6807 0.9998 1971877 ChemDiv1_003146 COc1ccc(CNC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(OC)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O23 mock treatment 283.5 91.2 0.48 278.2 90.8 0.47 0.6701 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 O24 mock treatment 107.9 -84.4 -0.44 93.1 -94.3 -0.49 -0.658 -0.9985 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P01 compound treatment 282.7 90.4 0.47 287.8 100.0 0.52 0.7024 0.9987 1971878 ChemDiv1_003147 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)N4CCN(Cc5ccccc5)CC4)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P02 compound treatment 283.9 91.6 0.48 287.5 100.0 0.52 0.7057 0.9991 1516943 ChemDiv1_003148 COc1ccc2nc(NC(=O)CSc3nc4ccccc4[nH]3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P03 compound treatment 288.7 96.4 0.5 286.7 99.3 0.52 0.7205 0.9999 1971879 ChemDiv1_003149 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)NCCCn5ccnc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P04 compound treatment 288.8 96.5 0.5 287.3 99.9 0.52 0.7231 0.9999 1374030 ChemDiv1_003150 CCOc1ccc2nc(SCC(=O)Nc3cccc(c3)C(=O)O)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P05 compound treatment 285.2 92.9 0.48 282.8 95.4 0.5 0.6933 0.9999 1971880 ChemDiv1_003151 Cc1c(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P06 compound treatment 290.6 98.3 0.51 285.4 98.0 0.51 0.7227 1.0 1615130 ChemDiv1_003152 O=C(Nc1ccc2c(c1)oc3ccccc32)c4ccc5OCCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P07 compound treatment 287.1 94.8 0.49 283.8 96.4 0.5 0.7039 1.0 1971881 ChemDiv1_003153 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P08 compound treatment 287.8 95.5 0.5 284.5 97.1 0.5 0.7091 1.0 1971882 ChemDiv1_003154 OC(=O)c1ccc(COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Br)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P09 compound treatment 287.6 95.3 0.5 285.7 98.3 0.51 0.7128 0.9999 1971883 ChemDiv1_003155 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCC4CCCO4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P10 compound treatment 287.8 95.5 0.5 286.1 98.7 0.51 0.715 0.9999 1945432 ChemDiv1_003156 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P11 compound treatment 282.6 90.3 0.47 280.3 92.9 0.48 0.6745 0.9999 1971884 ChemDiv1_003157 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc5OCOc5c4)C(=O)OCCOc6ccccc6)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P12 compound treatment 285.3 93.0 0.49 282.2 94.8 0.49 0.6914 1.0 1784060 ChemDiv1_003158 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P13 compound treatment 288.1 95.8 0.5 284.9 97.5 0.51 0.7117 1.0 1593304 ChemDiv1_003159 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P14 compound treatment 287.9 95.6 0.5 285.1 97.7 0.51 0.7117 1.0 1971885 ChemDiv1_003160 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N(CC)CC)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P15 compound treatment 282.6 90.3 0.47 286.1 98.7 0.51 0.6958 0.9991 1971886 ChemDiv1_003161 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P16 compound treatment 291.4 99.1 0.52 284.0 96.6 0.5 0.7205 0.9999 1739355 ChemDiv1_003162 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4ccc(O)c(CN(C)C)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P17 compound treatment 284.7 92.4 0.48 280.3 92.9 0.48 0.6822 1.0 1460769 ChemDiv1_003163 COC(=O)C1CCc2sc(NC(=O)CCN3C(=O)c4ccccc4C3=O)c(C(=O)OC)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P18 compound treatment 283.9 91.6 0.48 285.3 97.9 0.51 0.6977 0.9995 1733388 ChemDiv1_003164 COc1ccc(Nc2nc(Cl)nc(NC3CCCC3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P19 compound treatment 270.4 78.1 0.41 284.2 96.8 0.5 0.6438 0.9946 1947343 ChemDiv1_003165 COc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P20 compound treatment 279.6 87.3 0.46 282.4 95.0 0.49 0.6711 0.9992 1946374 ChemDiv1_003166 CC1(C)Cc2c(CO1)sc3nc(oc(=O)c23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P21 compound treatment 283.1 90.8 0.47 278.7 91.3 0.47 0.6704 1.0 1923870 ChemDiv1_003167 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P22 compound treatment 285.4 93.1 0.49 279.4 92.0 0.48 0.6815 1.0 1971887 ChemDiv1_003168 COc1ccc(OCCSc2nc3ccccc3n2CC(=O)N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P23 mock treatment 282.0 89.7 0.47 279.4 92.0 0.48 0.669 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.595 P24 mock treatment 108.8 -83.5 -0.44 104.0 -83.4 -0.43 -0.6146 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A01 compound treatment 289.0 97.1 0.51 289.1 101.0 0.53 0.7308 0.9998 1971888 ChemDiv1_003169 CN(C)c1ccc(cc1[N+](=O)[O-])C2CC(=NN2C(=O)c3ccc(F)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A02 compound treatment 273.6 81.7 0.43 283.9 96.2 0.5 0.6549 0.9969 1971889 ChemDiv1_003170 Brc1ccc2NC(=O)/C(=C\3/S/C(=N\S(=O)(=O)c4ccccc4)/NC3=O)/c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A03 compound treatment 282.2 90.3 0.47 287.7 100.0 0.52 0.7006 0.9988 1320513 ChemDiv1_003171 COc1ccc(cc1)c2cc(C(=O)N3CCN(CC3)c4ccccc4OC)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A04 compound treatment 280.0 88.1 0.46 285.2 97.5 0.51 0.6832 0.9988 1971890 ChemDiv1_003172 O=c1c2ccccc2c(=O)c3c4[nH]c5ccccc5oc4cc(NCc6ccccc6)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A05 compound treatment 284.7 92.8 0.48 286.4 98.7 0.51 0.705 0.9996 1579877 ChemDiv1_003173 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(OC)c3OC)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A06 compound treatment 283.1 91.2 0.48 286.0 98.3 0.51 0.6976 0.9994 1971891 ChemDiv1_003174 COc1ccc2nc(Nc3nc(O)cc(n3)c4ccccc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A07 compound treatment 276.6 84.7 0.44 274.8 87.1 0.45 0.6325 0.9999 1946104 ChemDiv1_003175 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCc3ccc(cc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A08 compound treatment 282.8 90.9 0.47 279.5 91.8 0.48 0.6726 1.0 1663451 ChemDiv1_003176 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A09 compound treatment 284.0 92.1 0.48 278.9 91.2 0.47 0.6748 1.0 1971892 ChemDiv1_003177 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(cc3)C(C)(C)C)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A10 compound treatment 282.6 90.7 0.47 285.0 97.3 0.51 0.6921 0.9995 1571603 ChemDiv1_003178 CC1=C(C(NC(=O)N1)c2cccc(Oc3ccccc3)c2)C(=O)OCc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A11 compound treatment 280.9 89.0 0.46 285.0 97.3 0.51 0.6858 0.9991 1971893 ChemDiv1_003179 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(cc3)C(C)(C)C)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A12 compound treatment 280.3 88.4 0.46 284.2 96.5 0.5 0.6807 0.9991 1923306 ChemDiv1_003180 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A13 compound treatment 283.8 91.9 0.48 284.1 96.4 0.5 0.6932 0.9998 1971894 ChemDiv1_003181 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)OC)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A14 compound treatment 278.5 86.6 0.45 281.1 93.4 0.49 0.6626 0.9994 1924022 ChemDiv1_003182 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A15 compound treatment 277.9 86.0 0.45 280.7 93.0 0.48 0.659 0.9993 1945599 ChemDiv1_003183 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A16 compound treatment 281.6 89.7 0.47 279.8 92.1 0.48 0.6693 0.9999 1971895 ChemDiv1_003184 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A17 compound treatment 281.8 89.9 0.47 278.8 91.1 0.47 0.6664 1.0 1945867 ChemDiv1_003185 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A18 compound treatment 279.8 87.9 0.46 279.5 91.8 0.48 0.6616 0.9998 1943173 ChemDiv1_003186 [O-][N+](=O)c1ccc(OCCOc2cccc(C=C3C(=O)NC(=O)NC3=O)c2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A19 compound treatment 276.0 84.1 0.44 280.4 92.7 0.48 0.6509 0.9989 1309298 ChemDiv1_003187 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A20 compound treatment 275.9 84.0 0.44 279.3 91.6 0.48 0.6464 0.9991 1971896 ChemDiv1_003188 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCSc3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A21 compound treatment 278.5 86.6 0.45 277.9 90.2 0.47 0.6509 0.9998 1971897 ChemDiv1_003189 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Br)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A22 compound treatment 277.7 85.8 0.45 277.6 89.9 0.47 0.6468 0.9998 1971898 ChemDiv1_003190 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCSc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A23 mock treatment 279.9 88.0 0.46 277.7 90.0 0.47 0.6553 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 A24 mock treatment 77.6 -114.0 -0.6 75.9 -112.0 -0.58 -0.8326 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B01 compound treatment 281.5 89.6 0.47 288.0 100.0 0.52 0.6991 0.9985 1603156 ChemDiv1_003191 CC(=O)Nc1ccc(cc1)C(=O)CSc2nc(O)c3ccccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B02 compound treatment 282.0 90.1 0.47 283.5 95.8 0.5 0.6844 0.9996 1491654 ChemDiv1_003192 COC(=O)c1ccc(Oc2nc(NC(C)C)nc(NC(C)C)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B03 compound treatment 282.1 90.2 0.47 284.0 96.3 0.5 0.6866 0.9995 1260827 ChemDiv1_003193 Cc1ccc2nc(oc2c1)c3cc(NC(=O)c4cccc(OCc5ccccc5)c4)ccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B04 compound treatment 283.6 91.7 0.48 283.7 96.0 0.5 0.691 0.9998 1164076 ChemDiv1_003194 OC(COc1ccccc1C(=O)Nc2ccccc2)CN3C(=O)c4ccccc4S3(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B05 compound treatment 283.5 91.6 0.48 279.3 91.6 0.48 0.6745 1.0 1971899 ChemDiv1_003195 COc1ccccc1OCCSc2nc3ccccc3n2CC(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B06 compound treatment 286.2 94.3 0.49 286.8 99.1 0.51 0.712 0.9997 1971900 ChemDiv1_003196 CCN(CC)CCCNc1nc(nc2ccccc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B07 compound treatment 280.7 88.8 0.46 285.6 97.9 0.51 0.6873 0.9989 1971901 ChemDiv1_003197 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B08 compound treatment 282.9 91.0 0.47 281.2 93.5 0.49 0.6792 0.9999 1547367 ChemDiv1_003198 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B09 compound treatment 280.7 88.8 0.46 284.1 96.4 0.5 0.6818 0.9992 1971902 ChemDiv1_003199 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OCCSCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B10 compound treatment 281.4 89.5 0.47 281.3 93.6 0.49 0.6741 0.9998 1971903 ChemDiv1_003200 Fc1ccc(cc1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B11 compound treatment 283.1 91.2 0.48 286.4 98.7 0.51 0.6991 0.9993 1784075 ChemDiv1_003201 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B12 compound treatment 282.5 90.6 0.47 280.9 93.2 0.48 0.6767 0.9999 1624483 ChemDiv1_003202 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B13 compound treatment 284.7 92.8 0.48 279.9 92.2 0.48 0.6811 1.0 1971904 ChemDiv1_003203 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B14 compound treatment 283.5 91.6 0.48 280.0 92.3 0.48 0.677 1.0 1465862 ChemDiv1_003204 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccc(Cl)cc5c4=O)C(=O)CC(C)(C)C3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B15 compound treatment 284.7 92.8 0.48 280.1 92.4 0.48 0.6818 1.0 1255871 ChemDiv1_003205 COC(=O)CN(c1nc(C)c(Cl)c(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B16 compound treatment 276.3 84.4 0.44 280.9 93.2 0.48 0.6538 0.9989 1419891 ChemDiv1_003206 CN1C2CCC1C=C(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B17 compound treatment 282.7 90.8 0.47 284.8 97.1 0.5 0.6917 0.9995 1368941 ChemDiv1_003207 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(n2)n3nc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B18 compound treatment 279.9 88.0 0.46 284.9 97.2 0.51 0.6818 0.9989 1971905 ChemDiv1_003208 COCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B19 compound treatment 278.3 86.4 0.45 273.3 85.6 0.44 0.6332 1.0 1971906 ChemDiv1_003209 CC(C)Nc1nc(NC(C)C)nc(OCCOC(=O)c2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B20 compound treatment 283.1 91.2 0.48 277.8 90.1 0.47 0.6675 1.0 1688615 ChemDiv1_003210 COc1ccc(cc1OC)C(=O)Nc2ccc3oc(nc3c2)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B21 compound treatment 280.4 88.5 0.46 276.0 88.3 0.46 0.6509 1.0 1971907 ChemDiv1_003211 CCOc1nc(SCCOc2ccc(C)cc2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B22 compound treatment 278.2 86.3 0.45 279.5 91.8 0.48 0.6557 0.9996 1543048 ChemDiv1_003212 COc1cc(ccc1OC(=O)CNc2ccc3OCOc3c2)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B23 mock treatment 280.8 88.9 0.46 279.2 91.5 0.48 0.6641 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 B24 mock treatment 82.5 -109.0 -0.57 80.8 -107.0 -0.56 -0.7966 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C01 compound treatment 287.4 95.5 0.5 286.7 99.0 0.51 0.7161 0.9999 1971908 ChemDiv1_003213 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)c3ccc(F)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C02 compound treatment 283.2 91.3 0.48 283.9 96.2 0.5 0.6903 0.9997 1572581 ChemDiv1_003214 Brc1ccc(NC(=O)CSC2=C(C#N)C3(CCC(CC3)c4ccccc4)C(C#N)C(=O)N2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C03 compound treatment 285.1 93.2 0.49 286.6 98.9 0.51 0.7072 0.9996 1946149 ChemDiv1_003215 COc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C04 compound treatment 284.2 92.3 0.48 285.0 97.3 0.51 0.698 0.9997 1971909 ChemDiv1_003216 Clc1ccc2[nH]c3c(cc(NC4CCCCC4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C05 compound treatment 290.9 99.0 0.52 292.9 105.0 0.55 0.7518 0.9996 1145067 ChemDiv1_003217 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)c(OC)c3)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C06 compound treatment 281.4 89.5 0.47 283.1 95.4 0.5 0.6807 0.9996 1574917 ChemDiv1_003218 COc1cc(cc(OC)c1OC)C(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C07 compound treatment 283.8 91.9 0.48 279.2 91.5 0.48 0.6752 1.0 1946274 ChemDiv1_003219 COc1cc(/C=C/2\C(=O)NC(=O)N(C)C2=O)ccc1OCc3ccc(cc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C08 compound treatment 283.3 91.4 0.48 286.7 99.0 0.51 0.7009 0.9993 1675008 ChemDiv1_003220 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C09 compound treatment 281.2 89.3 0.47 286.1 98.4 0.51 0.691 0.9989 1945717 ChemDiv1_003221 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C10 compound treatment 281.3 89.4 0.47 284.3 96.6 0.5 0.6847 0.9993 1497488 ChemDiv1_003222 CC1=C(C(NC(=O)N1)c2cccc(Oc3ccccc3)c2)C(=O)OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C11 compound treatment 284.3 92.4 0.48 281.7 94.0 0.49 0.6862 1.0 1946172 ChemDiv1_003223 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C12 compound treatment 278.7 86.8 0.45 284.2 96.5 0.5 0.6748 0.9987 1971910 ChemDiv1_003224 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C13 compound treatment 284.8 92.9 0.48 283.2 95.5 0.5 0.6936 0.9999 1946427 ChemDiv1_003225 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(cc3)C(C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C14 compound treatment 279.5 87.6 0.46 280.4 92.7 0.48 0.6638 0.9997 1971911 ChemDiv1_003226 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C15 compound treatment 281.2 89.3 0.47 285.0 97.3 0.51 0.6869 0.9992 1971912 ChemDiv1_003227 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)OC)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C16 compound treatment 282.5 90.6 0.47 279.7 92.0 0.48 0.6723 1.0 1971913 ChemDiv1_003228 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3cccc(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C17 compound treatment 280.6 88.7 0.46 281.6 93.9 0.49 0.6722 0.9996 1971914 ChemDiv1_003229 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C18 compound treatment 281.6 89.7 0.47 281.0 93.3 0.48 0.6737 0.9998 1943237 ChemDiv1_003230 CN1C(=O)N(C)C(=O)C(=Cc2cccc(OCCOc3ccc(cc3)[N+](=O)[O-])c2)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C19 compound treatment 283.1 91.2 0.48 283.8 96.1 0.5 0.6895 0.9997 1157426 ChemDiv1_003231 COc1cc(cc(OC)c1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C20 compound treatment 282.3 90.4 0.47 279.7 92.0 0.48 0.6715 1.0 1971915 ChemDiv1_003232 CCOC(=O)CSCCOc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C21 compound treatment 282.4 90.5 0.47 279.6 91.9 0.48 0.6715 1.0 1710015 ChemDiv1_003233 Cc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(cc3)C(C)(C)C)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C22 compound treatment 278.2 86.3 0.45 276.2 88.5 0.46 0.6435 0.9999 1971916 ChemDiv1_003234 CCOC(=O)CSCCOc1ccc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C23 mock treatment 285.2 93.3 0.49 280.9 93.2 0.48 0.6866 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 C24 mock treatment 77.8 -114.0 -0.6 77.4 -110.0 -0.57 -0.8264 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D01 compound treatment 287.1 95.2 0.5 289.3 102.0 0.53 0.7245 0.9995 1971917 ChemDiv1_003235 COc1ccc(cc1OC)C(=O)CSc2nc(O)c3ccccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D02 compound treatment 287.7 95.8 0.5 288.5 101.0 0.52 0.7238 0.9997 1245752 ChemDiv1_003236 CCNc1nc(NCC)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D03 compound treatment 297.1 105.0 0.55 292.1 104.0 0.54 0.7717 1.0 1683341 ChemDiv1_003237 O=C(Nc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D04 compound treatment 283.6 91.7 0.48 287.0 99.3 0.52 0.7031 0.9993 1490278 ChemDiv1_003238 OC(CNS(=O)(=O)c1ccccc1C(=O)N2CCOCC2)COc3ccc(cc3)N4C(=O)C5CC=CCC5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D05 compound treatment 282.0 90.1 0.47 285.7 98.0 0.51 0.6925 0.9992 1971918 ChemDiv1_003239 COc1ccccc1OCCSc2nc3ccccc3n2CC(O)CO 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D06 compound treatment 286.5 94.6 0.49 286.4 98.7 0.51 0.7116 0.9998 1159575 ChemDiv1_003240 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2Cl)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D07 compound treatment 282.8 90.9 0.47 282.7 95.0 0.49 0.6844 0.9998 1441303 ChemDiv1_003241 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OCC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D08 compound treatment 284.0 92.1 0.48 281.9 94.2 0.49 0.6859 1.0 1971919 ChemDiv1_003242 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D09 compound treatment 284.4 92.5 0.48 284.7 97.0 0.5 0.6976 0.9998 1193799 ChemDiv1_003243 COc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OCC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D10 compound treatment 282.9 91.0 0.47 283.9 96.2 0.5 0.6892 0.9997 1971920 ChemDiv1_003244 [O-][N+](=O)c1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D11 compound treatment 284.1 92.2 0.48 283.9 96.2 0.5 0.6936 0.9998 1384080 ChemDiv1_003245 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2Cl)C(=O)Nc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D12 compound treatment 284.0 92.1 0.48 281.5 93.8 0.49 0.6844 1.0 1971921 ChemDiv1_003246 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D13 compound treatment 280.0 88.1 0.46 287.3 99.6 0.52 0.691 0.9982 1783908 ChemDiv1_003247 COc1ccc(CCN2C(SCC2=O)c3ccc(cc3)[N+](=O)[O-])cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D14 compound treatment 280.8 88.9 0.46 280.1 92.4 0.48 0.6675 0.9998 1971922 ChemDiv1_003248 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D15 compound treatment 282.3 90.4 0.47 280.6 92.9 0.48 0.6748 0.9999 1142854 ChemDiv1_003249 CCNc1nc(NC(C)C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D16 compound treatment 280.5 88.6 0.46 282.4 94.7 0.49 0.6748 0.9995 1736301 ChemDiv1_003250 CN1C2CCC1CC(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D17 compound treatment 284.0 92.1 0.48 283.0 95.3 0.5 0.6899 0.9999 1163540 ChemDiv1_003251 COc1nc(NS(=O)(=O)c2ccc(C)cc2)nc(C)c1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D18 compound treatment 279.1 87.2 0.45 281.2 93.5 0.49 0.6652 0.9995 1971923 ChemDiv1_003252 CN1C(=C(C(NC1=O)c2cccc(c2)C(F)(F)F)C(=O)OCCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D19 compound treatment 278.7 86.8 0.45 278.6 90.9 0.47 0.6542 0.9998 1971924 ChemDiv1_003253 CN(C)c1nc(SCCOC(=O)Nc2ccccc2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D20 compound treatment 276.6 84.7 0.44 277.6 89.9 0.47 0.6428 0.9996 1682976 ChemDiv1_003254 COc1ccc(cc1OC)C(=O)Nc2ccc3oc(Cc4ccc(Cl)cc4)nc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D21 compound treatment 279.5 87.6 0.46 276.8 89.1 0.46 0.6505 1.0 1971925 ChemDiv1_003255 CCNc1nc(NCC)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D22 compound treatment 280.2 88.3 0.46 275.0 87.3 0.45 0.6465 1.0 1971926 ChemDiv1_003256 Cc1ccc(NC(=O)c2ccc(o2)c3ccc(cc3)[N+](=O)[O-])cc1c4nc5ncccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D23 mock treatment 283.4 91.5 0.48 281.5 93.8 0.49 0.6822 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 D24 mock treatment 78.7 -113.0 -0.59 76.5 -111.0 -0.58 -0.8264 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E01 compound treatment 284.2 92.3 0.48 286.1 98.4 0.51 0.702 0.9995 1971927 ChemDiv1_003257 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(F)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E02 compound treatment 285.7 93.8 0.49 286.2 98.5 0.51 0.708 0.9997 1530853 ChemDiv1_003258 Cc1ccc(o1)c2c(C#N)c(SCC(=O)c3ccc(O)c(O)c3)nc4CCCCc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E03 compound treatment 279.9 88.0 0.46 281.3 93.6 0.49 0.6685 0.9996 1971928 ChemDiv1_003259 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E04 compound treatment 279.9 88.0 0.46 283.2 95.5 0.5 0.6755 0.9992 1971929 ChemDiv1_003260 Cc1cccc2oc3cc(Nc4ccccc4)c5c(=O)c6ccccc6c(=O)c5c3[nH]c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E05 compound treatment 286.1 94.2 0.49 285.4 97.7 0.51 0.7065 0.9999 1971930 ChemDiv1_003261 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E06 compound treatment 288.3 96.4 0.5 287.9 100.0 0.52 0.7238 0.9998 1971931 ChemDiv1_003262 CC1=CC(C)(C)N(C(=O)c2sc3ccccc3c2Cl)c4ccc(cc14)C(c5ccccc5)(c6ccccc6)c7ccccc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E07 compound treatment 279.1 87.2 0.45 286.0 98.3 0.51 0.6829 0.9983 1971932 ChemDiv1_003263 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)ccc1OCc4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E08 compound treatment 284.5 92.6 0.48 286.1 98.4 0.51 0.7032 0.9996 1784065 ChemDiv1_003264 [O-][N+](=O)c1cc2OCOc2cc1C3Nc4ccccc4NC5=C3C(=O)CC(C5)c6ccc(Cl)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E09 compound treatment 284.4 92.5 0.48 285.7 98.0 0.51 0.7013 0.9996 1951589 ChemDiv1_003265 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E10 compound treatment 264.2 72.3 0.38 278.2 90.5 0.47 0.5992 0.994 1971933 ChemDiv1_003266 Oc1cc(Cl)c([N+](=O)[O-])c2C3C=CCC3C(Nc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E11 compound treatment 284.9 93.0 0.49 285.7 98.0 0.51 0.7032 0.9997 1946198 ChemDiv1_003267 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E12 compound treatment 282.3 90.4 0.47 284.0 96.3 0.5 0.6873 0.9996 1971934 ChemDiv1_003268 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E13 compound treatment 286.9 95.0 0.5 290.6 103.0 0.53 0.7285 0.9993 1945904 ChemDiv1_003269 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E14 compound treatment 283.0 91.1 0.48 283.1 95.4 0.5 0.6866 0.9998 1971935 ChemDiv1_003270 COc1ccccc1OCCOc2c(Br)cc(C=C3C(=O)NC(=O)NC3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E15 compound treatment 282.9 91.0 0.47 290.6 103.0 0.53 0.7138 0.9982 1945713 ChemDiv1_003271 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(cc3)C(C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E16 compound treatment 282.1 90.2 0.47 283.8 96.1 0.5 0.6858 0.9996 1971936 ChemDiv1_003272 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E17 compound treatment 279.0 87.1 0.45 282.3 94.6 0.49 0.6689 0.9992 1971937 ChemDiv1_003273 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC#N)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E18 compound treatment 276.9 85.0 0.44 281.6 93.9 0.49 0.6586 0.9989 1923394 ChemDiv1_003274 [O-][N+](=O)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E19 compound treatment 283.3 91.4 0.48 279.3 91.6 0.48 0.6737 1.0 1710855 ChemDiv1_003275 Cc1ccc(SCC(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E20 compound treatment 279.3 87.4 0.46 277.6 89.9 0.47 0.6527 0.9999 1926305 ChemDiv1_003276 CCOC(=O)CSCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E21 compound treatment 281.6 89.7 0.47 278.4 90.7 0.47 0.6642 1.0 1971938 ChemDiv1_003277 Cc1ccc(cc1C)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(C)c(c3)[N+](=O)[O-])s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E22 compound treatment 277.4 85.5 0.45 278.6 90.9 0.47 0.6494 0.9996 1971939 ChemDiv1_003278 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E23 mock treatment 283.8 91.9 0.48 279.7 92.0 0.48 0.6771 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 E24 mock treatment 78.9 -113.0 -0.59 76.3 -111.0 -0.58 -0.8264 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F01 compound treatment 284.3 92.4 0.48 283.2 95.5 0.5 0.6918 0.9999 1971940 ChemDiv1_003279 COc1ccccc1C2CC(=NN2CN3C(=O)C(=O)c4ccccc34)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F02 compound treatment 283.9 92.0 0.48 287.2 99.5 0.52 0.705 0.9993 1371076 ChemDiv1_003280 COC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F03 compound treatment 283.7 91.8 0.48 288.4 101.0 0.52 0.7087 0.999 1254407 ChemDiv1_003281 CCOc1cc(OCC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4cccc(F)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F04 compound treatment 286.4 94.5 0.49 283.4 95.7 0.5 0.7002 1.0 1971941 ChemDiv1_003282 CC(C)C1=CC23CCC4C(C)(CCCC4(C)C3CC1C5C2C(=O)N(C5=O)c6ccc(cc6)S(=O)(=O)N)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F05 compound treatment 282.1 90.2 0.47 288.9 101.0 0.53 0.7046 0.9985 1971942 ChemDiv1_003283 CC(C)(C)c1ccc(OCCSc2nc3ccccc3n2CC(=O)N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F06 compound treatment 286.0 94.1 0.49 287.3 99.6 0.52 0.7131 0.9997 1391694 ChemDiv1_003284 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F07 compound treatment 281.7 89.8 0.47 285.2 97.5 0.51 0.6895 0.9992 1661399 ChemDiv1_003285 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F08 compound treatment 287.6 95.7 0.5 291.3 104.0 0.54 0.7337 0.9993 1351519 ChemDiv1_003286 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F09 compound treatment 282.4 90.5 0.47 290.9 103.0 0.54 0.7131 0.998 1367554 ChemDiv1_003287 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C(=O)OC(C)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F10 compound treatment 284.1 92.2 0.48 295.0 107.0 0.56 0.7344 0.9973 1971943 ChemDiv1_003288 [O-][N+](=O)c1cccc(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F11 compound treatment 285.7 93.8 0.49 286.8 99.1 0.51 0.7102 0.9997 1971944 ChemDiv1_003289 COc1cc(cc(OC)c1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F12 compound treatment 284.4 92.5 0.48 286.1 98.4 0.51 0.7028 0.9996 1971945 ChemDiv1_003290 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F13 compound treatment 281.2 89.3 0.47 285.2 97.5 0.51 0.6877 0.9991 1971946 ChemDiv1_003291 CCNc1nc(NCC)nc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F14 compound treatment 281.2 89.3 0.47 285.3 97.6 0.51 0.688 0.9991 1337077 ChemDiv1_003292 O=C(N1CCN(CC1)C(=O)c2cccc(c2)S(=O)(=O)N3CCCCC3)c4cccc(c4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F15 compound treatment 282.6 90.7 0.47 277.7 90.0 0.47 0.6653 1.0 1220453 ChemDiv1_003293 CCNc1nc(NCC)nc(NS(=O)(=O)c2ccc(C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F16 compound treatment 282.0 90.1 0.47 284.8 97.1 0.5 0.6892 0.9994 1313118 ChemDiv1_003294 CN1C2CCC1CC(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F17 compound treatment 283.6 91.7 0.48 286.8 99.1 0.51 0.7024 0.9993 1971947 ChemDiv1_003295 COc1nc(nc(C)c1Br)N(C)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F18 compound treatment 276.8 84.9 0.44 280.4 92.7 0.48 0.6538 0.9991 1677968 ChemDiv1_003296 CN1C(=C(C(NC1=O)c2ccc(Br)s2)C(=O)OCCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F19 compound treatment 282.0 90.1 0.47 284.3 96.6 0.5 0.6873 0.9995 1971948 ChemDiv1_003297 CCNc1nc(NCC)nc(SCCOC(=O)Nc2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F20 compound treatment 282.8 90.9 0.47 281.1 93.4 0.49 0.6785 0.9999 1175787 ChemDiv1_003298 O=C(Nc1cccc(NC(=O)c2ccc3OCCOc3c2)c1)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F21 compound treatment 276.5 84.6 0.44 280.2 92.5 0.48 0.652 0.9991 1971949 ChemDiv1_003299 CCNc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F22 compound treatment 281.2 89.3 0.47 278.8 91.1 0.47 0.6642 1.0 1971950 ChemDiv1_003300 OC(=O)C1Cc2c([nH]c3ccccc23)C(N1)c4cccc(O)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F23 mock treatment 282.9 91.0 0.47 282.9 95.2 0.49 0.6855 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 F24 mock treatment 81.2 -111.0 -0.58 77.5 -110.0 -0.57 -0.8135 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G01 compound treatment 284.1 92.2 0.48 282.8 95.1 0.49 0.6896 0.9999 1289023 ChemDiv1_003301 COc1ccc(cc1)c2cc(C(=O)NCc3ccc4OCOc4c3)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G02 compound treatment 285.7 93.8 0.49 282.9 95.2 0.49 0.6958 1.0 1971951 ChemDiv1_003302 COc1ccc(Nc2cc3sc4cc(C)ccc4[nH]c3c5c(=O)c6ccccc6c(=O)c25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G03 compound treatment 287.6 95.7 0.5 288.8 101.0 0.53 0.7245 0.9997 1971952 ChemDiv1_003303 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3c(OC)ccc4ccccc34)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G04 compound treatment 286.9 95.0 0.5 285.2 97.5 0.51 0.7087 0.9999 1919523 ChemDiv1_003304 OC(=O)c1cc(cc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G05 compound treatment 289.9 98.0 0.51 285.5 97.8 0.51 0.7209 1.0 1971953 ChemDiv1_003305 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G06 compound treatment 286.4 94.5 0.49 288.0 100.0 0.52 0.7171 0.9996 1783127 ChemDiv1_003306 [O-][N+](=O)c1ccc2c(Cl)c(sc2c1)C(=O)N3c4ccccc4CCc5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G07 compound treatment 280.3 88.4 0.46 282.2 94.5 0.49 0.6733 0.9995 1945993 ChemDiv1_003307 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCc4ccc(cc4)C(=O)O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G08 compound treatment 283.2 91.3 0.48 286.7 99.0 0.51 0.7006 0.9993 1971954 ChemDiv1_003308 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G09 compound treatment 287.6 95.7 0.5 293.3 106.0 0.55 0.7411 0.9989 1945817 ChemDiv1_003309 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G10 compound treatment 269.8 77.9 0.41 265.5 77.8 0.4 0.5732 1.0 1971955 ChemDiv1_003310 Oc1cc(Cl)c([N+](=O)[O-])c2C3C=CCC3C(Nc12)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G11 compound treatment 285.1 93.2 0.49 286.2 98.5 0.51 0.7057 0.9997 1945942 ChemDiv1_003311 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G12 compound treatment 280.6 88.7 0.46 286.2 98.5 0.51 0.6891 0.9987 1971956 ChemDiv1_003312 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G13 compound treatment 283.7 91.8 0.48 285.6 97.9 0.51 0.6984 0.9995 1945907 ChemDiv1_003313 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G14 compound treatment 284.8 92.9 0.48 285.1 97.4 0.51 0.7006 0.9998 1971957 ChemDiv1_003314 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G15 compound treatment 278.9 87.0 0.45 282.9 95.2 0.49 0.6707 0.9991 1946078 ChemDiv1_003315 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G16 compound treatment 283.0 91.1 0.48 282.6 94.9 0.49 0.6848 0.9998 1971958 ChemDiv1_003316 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G17 compound treatment 283.3 91.4 0.48 285.2 97.5 0.51 0.6954 0.9995 1971959 ChemDiv1_003317 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC=C)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G18 compound treatment 280.2 88.3 0.46 280.2 92.5 0.48 0.6656 0.9998 1971960 ChemDiv1_003318 CN1C(=O)N(C)C(=O)C(=Cc2cc(Br)ccc2OCCOc3ccccc3)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G19 compound treatment 282.2 90.3 0.47 277.5 89.8 0.47 0.6631 1.0 1171559 ChemDiv1_003319 Cc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)CSc3ccc(Cl)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G20 compound treatment 278.5 86.6 0.45 279.4 91.7 0.48 0.6564 0.9996 1946489 ChemDiv1_003320 CCOC(=O)CSCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(C)c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G21 compound treatment 283.0 91.1 0.48 279.5 91.8 0.48 0.6734 1.0 1971961 ChemDiv1_003321 Brc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccco3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G22 compound treatment 278.6 86.7 0.45 275.9 88.2 0.46 0.6439 1.0 1946403 ChemDiv1_003322 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G23 mock treatment 285.0 93.1 0.49 280.1 92.4 0.48 0.6829 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 G24 mock treatment 81.4 -110.0 -0.58 76.8 -111.0 -0.58 -0.8153 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H01 compound treatment 286.5 94.6 0.49 282.0 94.3 0.49 0.6955 1.0 1971962 ChemDiv1_003323 COc1ccc(cc1)C2=NN(CN3C(=O)C(=O)c4ccccc34)C(C2)c5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H02 compound treatment 284.3 92.4 0.48 288.4 101.0 0.52 0.7109 0.9992 1579638 ChemDiv1_003324 CC1(C)NC(=O)N(CC(O)COc2ccc(cc2)N3C(=O)C4CC=CCC4C3=O)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H03 compound treatment 290.8 98.9 0.52 283.1 95.4 0.5 0.7154 0.9998 1410958 ChemDiv1_003325 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3C)c4nc5ccc(C)cc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H04 compound treatment 282.1 90.2 0.47 286.4 98.7 0.51 0.6954 0.9991 1971963 ChemDiv1_003326 CCCCOC(=O)c1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H05 compound treatment 285.6 93.7 0.49 287.6 99.9 0.52 0.7127 0.9995 1784066 ChemDiv1_003327 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(c4)[N+](=O)[O-])C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H06 compound treatment 284.2 92.3 0.48 284.0 96.3 0.5 0.6943 0.9998 1408916 ChemDiv1_003328 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H07 compound treatment 285.9 94.0 0.49 287.3 99.6 0.52 0.7127 0.9996 1396747 ChemDiv1_003329 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cc(Cl)c(O)c(OC)c4)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H08 compound treatment 288.0 96.1 0.5 283.5 95.8 0.5 0.7065 1.0 1971964 ChemDiv1_003330 [O-][N+](=O)c1ccccc1C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H09 compound treatment 285.3 93.4 0.49 284.6 96.9 0.5 0.7006 0.9999 1682517 ChemDiv1_003331 CCOc1cc(cc(Cl)c1O)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCc4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H10 compound treatment 283.2 91.3 0.48 288.2 100.0 0.52 0.7061 0.9989 1971965 ChemDiv1_003332 Cc1cc(ccc1[N+](=O)[O-])C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H11 compound treatment 284.7 92.8 0.48 284.7 97.0 0.5 0.6987 0.9998 1971966 ChemDiv1_003333 COCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H12 compound treatment 283.4 91.5 0.48 283.7 96.0 0.5 0.6903 0.9998 1590612 ChemDiv1_003334 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cccc(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H13 compound treatment 282.9 91.0 0.47 284.4 96.7 0.5 0.691 0.9996 1971967 ChemDiv1_003335 CCNc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H14 compound treatment 280.9 89.0 0.46 285.7 98.0 0.51 0.6884 0.9989 1215375 ChemDiv1_003336 CC1CCN(CC1)S(=O)(=O)c2cc(ccc2C)C(=O)Oc3cccc4cccnc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H15 compound treatment 286.5 94.6 0.49 284.5 96.8 0.5 0.7047 1.0 1588087 ChemDiv1_003337 CCNc1nc(NC(C)C)nc(NS(=O)(=O)c2ccc(C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H16 compound treatment 283.5 91.6 0.48 289.1 101.0 0.53 0.7105 0.9988 1248308 ChemDiv1_003338 COc1ccc(cc1OC)C2NCCc3c2[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H17 compound treatment 280.2 88.3 0.46 280.9 93.2 0.48 0.6682 0.9997 1971968 ChemDiv1_003339 CN(C)c1nc(OCCOC(=O)Nc2ccccc2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H18 compound treatment 281.3 89.4 0.47 277.3 89.6 0.47 0.659 1.0 1971969 ChemDiv1_003340 CN1C(=C(C(NC1=O)c2ccc(cc2)C(F)(F)F)C(=O)OCCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H19 compound treatment 279.8 87.9 0.46 281.4 93.7 0.49 0.6685 0.9996 1971970 ChemDiv1_003341 CN(C)c1nc(SCCOC(=O)c2ccccc2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H20 compound treatment 285.8 93.9 0.49 283.0 95.3 0.5 0.6966 1.0 1601010 ChemDiv1_003342 O=C(Nc1ccc2nn(nc2c1)c3cccc4ccccc34)c5ccc6OCCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H21 compound treatment 280.4 88.5 0.46 276.0 88.3 0.46 0.6509 1.0 1971971 ChemDiv1_003343 CC(C)Nc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H22 compound treatment 278.0 86.1 0.45 281.5 93.8 0.49 0.6623 0.9992 1136747 ChemDiv1_003344 Cn1c(=O)n(C)c2n(Cc3ccc(Cl)cc3Cl)c(SCC(=O)O)nc2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H23 mock treatment 286.8 94.9 0.5 281.8 94.1 0.49 0.6958 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 H24 mock treatment 83.3 -109.0 -0.57 75.9 -112.0 -0.58 -0.8116 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I01 compound treatment 282.3 90.4 0.47 287.9 100.0 0.52 0.7017 0.9988 1624173 ChemDiv1_003345 COc1cccc(c1)c2cc(C(=O)Nc3ccncc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I02 compound treatment 287.4 95.5 0.5 284.0 96.3 0.5 0.7061 1.0 1971972 ChemDiv1_003346 CC(C)(C)c1ccc2[nH]c3c(cc(Nc4ccccc4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I03 compound treatment 268.4 76.5 0.4 265.8 78.1 0.41 0.5692 1.0 1971973 ChemDiv1_003347 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(Br)c(O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I04 compound treatment 282.8 90.9 0.47 281.3 93.6 0.49 0.6792 0.9999 1971974 ChemDiv1_003348 O=C1C2C3CC(C=C3)C2C(=O)N1c4cccc(Oc5ccc6C(=O)N(C(=O)c6c5)c7ccccc7)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I05 compound treatment 288.1 96.2 0.5 284.8 97.1 0.5 0.7117 1.0 1971975 ChemDiv1_003349 Cc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I06 compound treatment 284.5 92.6 0.48 282.0 94.3 0.49 0.6881 1.0 1971976 ChemDiv1_003350 CC1CC(N(C(=O)c2sc3cc(ccc3c2Cl)[N+](=O)[O-])c4ccccc4)c5ccccc5N1C(=O)Cc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I07 compound treatment 287.6 95.7 0.5 287.1 99.4 0.52 0.7183 0.9999 1971977 ChemDiv1_003351 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)ccc1OCc4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I08 compound treatment 283.4 91.5 0.48 284.7 97.0 0.5 0.694 0.9996 1587570 ChemDiv1_003352 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I09 compound treatment 286.9 95.0 0.5 284.7 97.0 0.5 0.7069 1.0 1928313 ChemDiv1_003353 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I10 compound treatment 241.9 50.0 0.26 239.2 51.5 0.27 0.3736 0.9999 1126339 ChemDiv1_003354 OC(=O)c1cccc2C3C=CCC3C(Nc12)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I11 compound treatment 282.1 90.2 0.47 288.5 101.0 0.52 0.7031 0.9986 1951821 ChemDiv1_003355 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I12 compound treatment 283.0 91.1 0.48 282.9 95.2 0.49 0.6859 0.9998 1971978 ChemDiv1_003356 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I13 compound treatment 283.2 91.3 0.48 284.2 96.5 0.5 0.6914 0.9997 1946266 ChemDiv1_003357 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I14 compound treatment 281.3 89.4 0.47 280.6 92.9 0.48 0.6711 0.9999 1971979 ChemDiv1_003358 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCCOc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I15 compound treatment 282.5 90.6 0.47 281.9 94.2 0.49 0.6803 0.9998 1971980 ChemDiv1_003359 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I16 compound treatment 280.6 88.7 0.46 283.1 95.4 0.5 0.6777 0.9994 1927744 ChemDiv1_003360 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc(Cl)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I17 compound treatment 285.3 93.4 0.49 280.1 92.4 0.48 0.6841 1.0 1946082 ChemDiv1_003361 Nc1ccc2nc(SCC(=O)NCCOc3ccc(Cl)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I18 compound treatment 278.2 86.3 0.45 281.0 93.3 0.48 0.6612 0.9993 1971981 ChemDiv1_003362 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OCCOc3ccc(cc3)[N+](=O)[O-])C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I19 compound treatment 285.5 93.6 0.49 282.6 94.9 0.49 0.694 1.0 1971982 ChemDiv1_003363 Brc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)CN3CCOCC3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I20 compound treatment 284.0 92.1 0.48 281.7 94.0 0.49 0.6851 1.0 1971983 ChemDiv1_003364 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCBr 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I21 compound treatment 279.0 87.1 0.45 282.0 94.3 0.49 0.6678 0.9993 1531569 ChemDiv1_003365 Cc1ccc(cc1C)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(Br)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I22 compound treatment 279.6 87.7 0.46 281.0 93.3 0.48 0.6663 0.9996 1452631 ChemDiv1_003366 Cc1ccc(cc1)n2c(=O)c3c4CCCc4sc3[nH]c2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I23 mock treatment 286.4 94.5 0.49 280.4 92.7 0.48 0.6892 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 I24 mock treatment 80.2 -112.0 -0.58 80.4 -107.0 -0.56 -0.8065 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J01 compound treatment 285.7 93.8 0.49 285.8 98.1 0.51 0.7065 0.9998 1661937 ChemDiv1_003367 COc1ccc(cc1)C2CC(=NN2C(=O)C)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J02 compound treatment 285.9 94.0 0.49 282.8 95.1 0.49 0.6962 1.0 1026994 ChemDiv1_003368 O=C1N(Cc2ccccc2)S(=O)(=O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J03 compound treatment 285.0 93.1 0.49 287.1 99.4 0.52 0.7087 0.9995 1532122 ChemDiv1_003369 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3ccc(O)c(c3)c4nc5cc(C)ccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J04 compound treatment 285.9 94.0 0.49 282.8 95.1 0.49 0.6962 1.0 1692805 ChemDiv1_003370 NC(=O)c1c(NC(=O)c2cc3cc(Br)ccc3oc2=O)sc4CCCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J05 compound treatment 286.3 94.4 0.49 284.6 96.9 0.5 0.7043 0.9999 1971984 ChemDiv1_003371 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N(C)C)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J06 compound treatment 288.4 96.5 0.5 284.0 96.3 0.5 0.7098 1.0 1658192 ChemDiv1_003372 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccccc5c4=O)C(=O)CCC3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J07 compound treatment 285.0 93.1 0.49 285.0 97.3 0.51 0.701 0.9998 1971985 ChemDiv1_003373 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J08 compound treatment 281.8 89.9 0.47 286.6 98.9 0.51 0.695 0.999 1971986 ChemDiv1_003374 [O-][N+](=O)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J09 compound treatment 282.4 90.5 0.47 287.2 99.5 0.52 0.6995 0.999 1575886 ChemDiv1_003375 COc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J10 compound treatment 281.6 89.7 0.47 280.5 92.8 0.48 0.6719 0.9999 1265001 ChemDiv1_003376 O=C(N1CCN(Cc2ccccc2)CC1)c3cc(nc4ccccc34)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J11 compound treatment 284.4 92.5 0.48 287.2 99.5 0.52 0.7068 0.9994 1580220 ChemDiv1_003377 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J12 compound treatment 282.7 90.8 0.47 284.3 96.6 0.5 0.6899 0.9996 1630930 ChemDiv1_003378 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3NC2c4coc5c(Cl)cc(Cl)cc5c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J13 compound treatment 284.0 92.1 0.48 283.3 95.6 0.5 0.691 0.9999 1971987 ChemDiv1_003379 CC(C)Nc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J14 compound treatment 285.8 93.9 0.49 283.4 95.7 0.5 0.698 1.0 1396540 ChemDiv1_003380 CCOC(=O)c1sc(NC(=O)c2cccc(c2)S(=O)(=O)N3CCCCCC3)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J15 compound treatment 282.9 91.0 0.47 283.7 96.0 0.5 0.6884 0.9997 1459151 ChemDiv1_003381 COc1nc(NS(=O)(=O)c2ccc(NC(=O)C)cc2)nc(C)c1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J16 compound treatment 286.5 94.6 0.49 283.4 95.7 0.5 0.7006 1.0 1506608 ChemDiv1_003382 COc1ccc(cc1)C2NCCc3c2[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J17 compound treatment 284.9 93.0 0.49 283.5 95.8 0.5 0.6951 0.9999 1971988 ChemDiv1_003383 CCNc1nc(NCC)nc(OCCOC(=O)Nc2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J18 compound treatment 278.7 86.8 0.45 282.7 95.0 0.49 0.6693 0.9991 1521396 ChemDiv1_003384 CCOc1cc(cc(Cl)c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J19 compound treatment 278.8 86.9 0.45 280.5 92.8 0.48 0.6615 0.9995 1971989 ChemDiv1_003385 CCNc1nc(NCC)nc(SCCOC(=O)c2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J20 compound treatment 281.6 89.7 0.47 277.4 89.7 0.47 0.6605 1.0 1714049 ChemDiv1_003386 CCOc1cc(ccc1OCc2ccc(F)cc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J21 compound treatment 282.0 90.1 0.47 279.3 91.6 0.48 0.6689 1.0 1327959 ChemDiv1_003387 COc1nc(nc(C)c1Cl)N(CC=C)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J22 compound treatment 281.9 90.0 0.47 284.7 97.0 0.5 0.6884 0.9994 1971990 ChemDiv1_003388 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5ccc(Cl)c(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J23 mock treatment 283.9 92.0 0.48 278.6 90.9 0.47 0.6734 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 J24 mock treatment 83.1 -109.0 -0.57 79.6 -108.0 -0.56 -0.7987 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K01 compound treatment 285.1 93.2 0.49 287.7 100.0 0.52 0.7113 0.9994 1939971 ChemDiv1_003389 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(NC(=O)c3sc4cc(C)ccc4c3Cl)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K02 compound treatment 286.8 94.9 0.5 281.5 93.8 0.49 0.6947 1.0 1971991 ChemDiv1_003390 Cc1ccc(Nc2cc3oc4cc(ccc4[nH]c3c5c(=O)c6ccccc6c(=O)c25)C(C)(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K03 compound treatment 287.1 95.2 0.5 288.7 101.0 0.52 0.7223 0.9996 1946111 ChemDiv1_003391 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(o3)c4ccc(cc4)C(=O)O)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K04 compound treatment 283.3 91.4 0.48 279.5 91.8 0.48 0.6745 1.0 1538577 ChemDiv1_003392 CCOC(=O)CCN1C(=O)c2ccccc2S1(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K05 compound treatment 287.9 96.0 0.5 281.6 93.9 0.49 0.6992 0.9999 1971992 ChemDiv1_003393 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K06 compound treatment 286.8 94.9 0.5 286.9 99.2 0.52 0.7146 0.9998 1971993 ChemDiv1_003394 Cc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)c3sc4cc(ccc4c3Cl)[N+](=O)[O-])c5ccccc52 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K07 compound treatment 287.2 95.3 0.5 283.0 95.3 0.5 0.7017 1.0 1971994 ChemDiv1_003395 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)ccc1OCc4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K08 compound treatment 282.4 90.5 0.47 284.7 97.0 0.5 0.6903 0.9995 1971995 ChemDiv1_003396 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc4ccccc34)C(=O)CC(C2)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K09 compound treatment 282.7 90.8 0.47 290.1 102.0 0.53 0.7112 0.9983 1971996 ChemDiv1_003397 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K10 compound treatment 106.4 -85.5 -0.45 107.6 -80.1 -0.42 -0.6099 -0.9994 1124004 ChemDiv1_003398 OC(=O)c1cc2C3C=CCC3CN4C(C5CC=CC5c(c1)c42)c6ccccc6F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K11 compound treatment 285.6 93.7 0.49 282.7 95.0 0.49 0.6947 1.0 1971997 ChemDiv1_003399 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K12 compound treatment 280.4 88.5 0.46 282.3 94.6 0.49 0.6741 0.9995 1971998 ChemDiv1_003400 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K13 compound treatment 284.8 92.9 0.48 288.5 101.0 0.52 0.7131 0.9992 1946027 ChemDiv1_003401 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K14 compound treatment 285.5 93.6 0.49 283.0 95.3 0.5 0.6955 1.0 1927017 ChemDiv1_003402 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K15 compound treatment 287.0 95.1 0.5 282.9 95.2 0.49 0.7006 1.0 1946141 ChemDiv1_003403 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K16 compound treatment 282.7 90.8 0.47 279.2 91.5 0.48 0.6712 1.0 1971999 ChemDiv1_003404 COc1ccccc1OCCOc2c(Cl)cc(C=C3C(=O)N(C)C(=O)N(C)C3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K17 compound treatment 286.5 94.6 0.49 280.6 92.9 0.48 0.6903 0.9999 1933204 ChemDiv1_003405 CCOc1ccc2nc(SCc3c[nH]c4cc(ccc34)[N+](=O)[O-])sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K18 compound treatment 280.7 88.8 0.46 281.8 94.1 0.49 0.6733 0.9996 1972000 ChemDiv1_003406 [O-][N+](=O)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K19 compound treatment 283.6 91.7 0.48 279.1 91.4 0.47 0.6741 1.0 1972001 ChemDiv1_003407 Brc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3cccs3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K20 compound treatment 282.4 90.5 0.47 280.3 92.6 0.48 0.6741 1.0 1972002 ChemDiv1_003408 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCBr 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K21 compound treatment 281.7 89.8 0.47 279.7 92.0 0.48 0.6693 0.9999 1972003 ChemDiv1_003409 Cc1ccc(cc1C)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(cc3)[N+](=O)[O-])s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K22 compound treatment 282.4 90.5 0.47 282.1 94.4 0.49 0.6807 0.9998 1933479 ChemDiv1_003410 CCn1c(SCC(=O)c2ccccc2)nc3sc4COC(C)(C)Cc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K23 mock treatment 282.3 90.4 0.47 279.7 92.0 0.48 0.6715 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 K24 mock treatment 81.7 -110.0 -0.57 79.5 -108.0 -0.56 -0.8043 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L01 compound treatment 284.7 92.8 0.48 285.4 97.7 0.51 0.7013 0.9997 1610231 ChemDiv1_003411 OC(=O)CCC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L02 compound treatment 287.9 96.0 0.5 282.7 95.0 0.49 0.7032 1.0 1182586 ChemDiv1_003412 NC(=O)CN1C(=O)c2ccccc2S1(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L03 compound treatment 281.1 89.2 0.47 282.4 94.7 0.49 0.677 0.9996 1339606 ChemDiv1_003413 COc1cc(OC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4ccc(OC)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L04 compound treatment 287.5 95.6 0.5 286.5 98.8 0.51 0.7157 0.9999 1949633 ChemDiv1_003414 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc3cc(Br)ccc3oc2=O)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L05 compound treatment 285.3 93.4 0.49 288.2 100.0 0.52 0.7138 0.9994 1356931 ChemDiv1_003415 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L06 compound treatment 284.3 92.4 0.48 283.2 95.5 0.5 0.6918 0.9999 1222926 ChemDiv1_003416 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L07 compound treatment 285.5 93.6 0.49 283.9 96.2 0.5 0.6988 0.9999 1140644 ChemDiv1_003417 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L08 compound treatment 285.6 93.7 0.49 284.2 96.5 0.5 0.7002 0.9999 1700704 ChemDiv1_003418 Cc1nc2ccccc2c(=O)n1NC(=O)c3cc(nc4ccccc34)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L09 compound treatment 282.5 90.6 0.47 285.0 97.3 0.51 0.6917 0.9994 1374217 ChemDiv1_003419 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(O)c(OC)c4)C(=O)OCC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L10 compound treatment 284.0 92.1 0.48 284.5 96.8 0.5 0.6954 0.9997 1972004 ChemDiv1_003420 CC(=O)c1sc(nc1C)N2N=C(CC2c3ccc(F)cc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L11 compound treatment 282.6 90.7 0.47 283.3 95.6 0.5 0.6859 0.9997 1349609 ChemDiv1_003421 CCCOc1ccc(cc1)C2NC(=O)NC(=C2C(=O)OCc3ccc(OC)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L12 compound treatment 283.2 91.3 0.48 281.7 94.0 0.49 0.6822 0.9999 1972005 ChemDiv1_003422 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L13 compound treatment 283.4 91.5 0.48 283.4 95.7 0.5 0.6892 0.9998 1621369 ChemDiv1_003423 Cc1cc(C)nc(n1)N(CN2C(=O)c3ccccc3S2(=O)=O)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L14 compound treatment 283.1 91.2 0.48 282.2 94.5 0.49 0.6837 0.9999 1422482 ChemDiv1_003424 Nc1nc(CSc2nc(N)c3nc[nH]c3n2)cs1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L15 compound treatment 280.6 88.7 0.46 279.8 92.1 0.48 0.6656 0.9999 1481333 ChemDiv1_003425 Cc1cc(C)n(n1)c2cc(C)nc(NS(=O)(=O)c3ccc(C)cc3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L16 compound treatment 284.3 92.4 0.48 283.6 95.9 0.5 0.6932 0.9999 1558798 ChemDiv1_003426 CCOc1cc(cc(Cl)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L17 compound treatment 284.4 92.5 0.48 283.1 95.4 0.5 0.6918 0.9999 1972006 ChemDiv1_003427 CN(C)c1nc(OCCOC(=O)c2ccccc2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L18 compound treatment 279.2 87.3 0.46 283.0 95.3 0.5 0.6722 0.9991 1406508 ChemDiv1_003428 COc1cc(cc(OC)c1OC)C(=O)N2N=C(CC2c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L19 compound treatment 284.3 92.4 0.48 283.5 95.8 0.5 0.6929 0.9999 1972007 ChemDiv1_003429 CCNc1nc(NC(C)C)nc(SCCOc2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L20 compound treatment 280.7 88.8 0.46 280.3 92.6 0.48 0.6678 0.9998 1972008 ChemDiv1_003430 CCOC(=O)c1ccc(Nc2nc3nonc3nc2N4CCC(Cc5ccccc5)CC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L21 compound treatment 282.4 90.5 0.47 279.4 91.7 0.48 0.6708 1.0 1300331 ChemDiv1_003431 COc1nc(nc(C)c1Br)N(CC=C)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L22 compound treatment 283.9 92.0 0.48 277.6 89.9 0.47 0.6697 0.9999 1972009 ChemDiv1_003432 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L23 mock treatment 281.5 89.6 0.47 279.8 92.1 0.48 0.6689 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 L24 mock treatment 78.0 -114.0 -0.59 81.2 -107.0 -0.55 -0.8117 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M01 compound treatment 283.6 91.7 0.48 287.6 99.9 0.52 0.7053 0.9992 1705941 ChemDiv1_003433 Cc1ccc(o1)c2cc(C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M02 compound treatment 281.9 90.0 0.47 284.3 96.6 0.5 0.6869 0.9994 1972010 ChemDiv1_003434 CC(C)(C)c1ccc2[nH]c3c(cc(NC4CCCCC4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M03 compound treatment 286.1 94.2 0.49 284.3 96.6 0.5 0.7024 0.9999 1972011 ChemDiv1_003435 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OC)c(OC)c3OC)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M04 compound treatment 287.7 95.8 0.5 286.0 98.3 0.51 0.7146 0.9999 1530636 ChemDiv1_003436 CC1CC(Nc2ccc(C)cc2)c3cccc(C)c3N1C(=O)c4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M05 compound treatment 286.2 94.3 0.49 284.3 96.6 0.5 0.7028 0.9999 1972012 ChemDiv1_003437 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M06 compound treatment 288.8 96.9 0.51 282.0 94.3 0.49 0.7039 0.9999 1523741 ChemDiv1_003438 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(Cl)c2)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M07 compound treatment 286.4 94.5 0.49 284.3 96.6 0.5 0.7035 1.0 1972013 ChemDiv1_003439 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCc4ccc(cc4)C(=O)O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M08 compound treatment 280.9 89.0 0.46 285.2 97.5 0.51 0.6866 0.9991 1161372 ChemDiv1_003440 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccncc4)C(=O)OCCc5ccccc5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M09 compound treatment 288.4 96.5 0.5 280.5 92.8 0.48 0.697 0.9998 1945768 ChemDiv1_003441 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M10 compound treatment 288.8 96.9 0.51 288.9 101.0 0.53 0.7293 0.9998 1736489 ChemDiv1_003442 CCOC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M11 compound treatment 283.2 91.3 0.48 285.0 97.3 0.51 0.6943 0.9996 1972014 ChemDiv1_003443 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M12 compound treatment 278.7 86.8 0.45 281.9 94.2 0.49 0.6663 0.9992 1972015 ChemDiv1_003444 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3cccc(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M13 compound treatment 284.3 92.4 0.48 284.0 96.3 0.5 0.6947 0.9998 1972016 ChemDiv1_003445 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)OC)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M14 compound treatment 285.9 94.0 0.49 285.6 97.9 0.51 0.7065 0.9998 1943089 ChemDiv1_003446 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M15 compound treatment 283.9 92.0 0.48 284.1 96.4 0.5 0.6936 0.9998 1946074 ChemDiv1_003447 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M16 compound treatment 280.1 88.2 0.46 279.8 92.1 0.48 0.6638 0.9998 1972017 ChemDiv1_003448 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc(Br)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M17 compound treatment 283.2 91.3 0.48 286.2 98.5 0.51 0.6987 0.9994 1413611 ChemDiv1_003449 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc4ccccc4c3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M18 compound treatment 282.6 90.7 0.47 278.5 90.8 0.47 0.6682 1.0 1923260 ChemDiv1_003450 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M19 compound treatment 284.2 92.3 0.48 282.0 94.3 0.49 0.687 1.0 1783241 ChemDiv1_003451 Cc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(C)c(c3)[N+](=O)[O-])s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M20 compound treatment 280.3 88.4 0.46 279.6 91.9 0.48 0.6638 0.9998 1943259 ChemDiv1_003452 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M21 compound treatment 284.5 92.6 0.48 281.1 93.4 0.49 0.6848 1.0 1356589 ChemDiv1_003453 COc1cccc(c1)C(=O)Nc2nnc(CCS(=O)(=O)c3cc(Cl)ccc3Cl)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M22 compound treatment 279.6 87.7 0.46 281.1 93.4 0.49 0.6667 0.9996 1972018 ChemDiv1_003454 CC1(C)Cc2c(CO1)sc3nc(SCC#N)n(c4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M23 mock treatment 284.9 93.0 0.49 277.8 90.1 0.47 0.6741 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 M24 mock treatment 203.5 11.6 0.06 187.8 0.0688 0.0 0.0431 0.7113 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N01 compound treatment 283.8 91.9 0.48 284.9 97.2 0.51 0.6962 0.9997 1972019 ChemDiv1_003455 COc1ccc(cc1OC)C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N02 compound treatment 285.0 93.1 0.49 285.2 97.5 0.51 0.7017 0.9998 1710765 ChemDiv1_003456 OC(COc1ccc2ccccc2c1)CN3C(=O)c4ccccc4S3(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N03 compound treatment 285.8 93.9 0.49 281.1 93.4 0.49 0.6896 1.0 1972020 ChemDiv1_003457 COc1cc(cc(OC)c1OC)C(=O)OCCCNC2=NS(=O)(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N04 compound treatment 281.7 89.8 0.47 286.1 98.4 0.51 0.6928 0.999 1972021 ChemDiv1_003458 CCOCCOC(=O)c1ccc(NC(=O)C2COc3ccccc3O2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N05 compound treatment 285.9 94.0 0.49 283.4 95.7 0.5 0.6984 1.0 1784068 ChemDiv1_003459 CCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3[N+](=O)[O-])C(=O)CC(C2)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N06 compound treatment 284.4 92.5 0.48 285.3 97.6 0.51 0.6998 0.9997 1415476 ChemDiv1_003460 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N07 compound treatment 282.4 90.5 0.47 293.3 106.0 0.55 0.7219 0.9972 1972022 ChemDiv1_003461 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3[N+](=O)[O-])C(=O)CC(C2)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N08 compound treatment 286.2 94.3 0.49 287.3 99.6 0.52 0.7138 0.9997 1430680 ChemDiv1_003462 COc1ccc(cc1Br)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N09 compound treatment 282.8 90.9 0.47 284.8 97.1 0.5 0.6921 0.9995 1972023 ChemDiv1_003463 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(O)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N10 compound treatment 286.4 94.5 0.49 282.9 95.2 0.49 0.6984 1.0 1972024 ChemDiv1_003464 CCCCc1c(C#N)c(N)nc2sc(C(=O)c3ccc(cc3)[N+](=O)[O-])c(N)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N11 compound treatment 288.5 96.6 0.5 282.4 94.7 0.49 0.7043 0.9999 1242152 ChemDiv1_003465 CC1=C(C(NC(=O)N1)c2ccc(OCc3ccccc3)cc2)C(=O)OCC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N12 compound treatment 282.1 90.2 0.47 284.4 96.7 0.5 0.6881 0.9995 1242806 ChemDiv1_003466 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N13 compound treatment 282.3 90.4 0.47 279.4 91.7 0.48 0.6704 1.0 1972025 ChemDiv1_003467 Cc1cc(C)n(n1)c2cc(C)nc(N)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N14 compound treatment 285.7 93.8 0.49 283.2 95.5 0.5 0.6969 1.0 1925786 ChemDiv1_003468 Cc1nnc(SCC(=O)OCN2C(=O)c3ccccc3C2=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N15 compound treatment 280.5 88.6 0.46 279.1 91.4 0.47 0.6627 0.9999 1354691 ChemDiv1_003469 Cc1cc(C)n(n1)c2cc(C)nc(NS(=O)(=O)c3ccccc3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N16 compound treatment 280.6 88.7 0.46 278.8 91.1 0.47 0.6619 0.9999 1947478 ChemDiv1_003470 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N17 compound treatment 281.1 89.2 0.47 282.7 95.0 0.49 0.6781 0.9996 1972026 ChemDiv1_003471 CCNc1nc(NCC)nc(OCCOC(=O)c2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N18 compound treatment 282.7 90.8 0.47 285.2 97.5 0.51 0.6932 0.9994 1972027 ChemDiv1_003472 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N19 compound treatment 283.7 91.8 0.48 279.1 91.4 0.47 0.6745 1.0 1972028 ChemDiv1_003473 CCOc1nc(SCCOc2ccccc2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N20 compound treatment 282.2 90.3 0.47 279.3 91.6 0.48 0.6697 1.0 1951367 ChemDiv1_003474 CCOc1c(Br)cc(cc1OC)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N21 compound treatment 282.1 90.2 0.47 280.0 92.3 0.48 0.6719 1.0 1590736 ChemDiv1_003475 COc1cc(C)nc(n1)N(Cc2ccccc2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N22 compound treatment 281.4 89.5 0.47 280.1 92.4 0.48 0.6697 0.9999 1972029 ChemDiv1_003476 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N23 mock treatment 284.5 92.6 0.48 277.1 89.4 0.46 0.6701 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 N24 mock treatment 208.8 16.9 0.09 187.9 0.169 0.0 0.063 0.7141 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O01 compound treatment 290.4 98.5 0.51 283.6 95.9 0.5 0.7157 0.9999 1706680 ChemDiv1_003477 Cc1cc(NC(=O)c2cc(nc3ccccc23)c4ccc(Br)cc4)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O02 compound treatment 285.0 93.1 0.49 280.7 93.0 0.48 0.6852 1.0 1972030 ChemDiv1_003478 Cc1ccc(Nc2cc3oc4cc(C)ccc4[nH]c3c5c(=O)c6ccccc6c(=O)c25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O03 compound treatment 282.9 91.0 0.47 282.3 94.6 0.49 0.6833 0.9998 1972031 ChemDiv1_003479 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OC(=O)c4cccs4)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O04 compound treatment 283.4 91.5 0.48 283.8 96.1 0.5 0.6906 0.9997 1202017 ChemDiv1_003480 COc1ccc2c(C)nc(Nc3nc(O)cc(n3)c4ccccc4)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O05 compound treatment 284.4 92.5 0.48 283.7 96.0 0.5 0.694 0.9999 1972032 ChemDiv1_003481 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCc4ccccc4C#N)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O06 compound treatment 283.0 91.1 0.48 280.3 92.6 0.48 0.6763 1.0 1972033 ChemDiv1_003482 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O07 compound treatment 288.0 96.1 0.5 283.2 95.5 0.5 0.7054 1.0 1928207 ChemDiv1_003483 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O08 compound treatment 284.1 92.2 0.48 282.9 95.2 0.49 0.6899 0.9999 1972034 ChemDiv1_003484 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O09 compound treatment 287.0 95.1 0.5 283.2 95.5 0.5 0.7017 1.0 1972035 ChemDiv1_003485 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(cc3)C(C)C)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O10 compound treatment 285.8 93.9 0.49 281.6 93.9 0.49 0.6914 1.0 1673480 ChemDiv1_003486 CN(C)CCn1c(NC(=O)c2ccc(Cl)cc2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O11 compound treatment 283.5 91.6 0.48 282.9 95.2 0.49 0.6877 0.9999 1945589 ChemDiv1_003487 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O12 compound treatment 283.3 91.4 0.48 281.6 93.9 0.49 0.6822 0.9999 1972036 ChemDiv1_003488 COc1ccccc1OCCOc2c(Cl)cc(C=C3C(=O)NC(=O)NC3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O13 compound treatment 284.5 92.6 0.48 286.0 98.3 0.51 0.7028 0.9996 1972037 ChemDiv1_003489 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O14 compound treatment 283.7 91.8 0.48 280.5 92.8 0.48 0.6796 1.0 1972038 ChemDiv1_003490 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O15 compound treatment 282.8 90.9 0.47 279.9 92.2 0.48 0.6741 1.0 1972039 ChemDiv1_003491 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)OC)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O16 compound treatment 281.7 89.8 0.47 285.9 98.2 0.51 0.6921 0.9991 1972040 ChemDiv1_003492 COc1ccccc1OCCOc2c(Br)cc(C=C3C(=O)N(C)C(=O)N(C)C3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O17 compound treatment 285.2 93.3 0.49 281.4 93.7 0.49 0.6885 1.0 1487104 ChemDiv1_003493 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(C)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O18 compound treatment 285.4 93.5 0.49 277.2 89.5 0.47 0.6738 0.9997 1972041 ChemDiv1_003494 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O19 compound treatment 282.3 90.4 0.47 282.0 94.3 0.49 0.68 0.9998 1783242 ChemDiv1_003495 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O20 compound treatment 283.6 91.7 0.48 279.6 91.9 0.48 0.6759 1.0 1926411 ChemDiv1_003496 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O21 compound treatment 284.3 92.4 0.48 281.8 94.1 0.49 0.6866 1.0 1972042 ChemDiv1_003497 O=C/1N\C(=N\S(=O)(=O)c2ccccc2)\S\C1=C/c3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O22 compound treatment 279.7 87.8 0.46 280.7 93.0 0.48 0.6656 0.9996 1932970 ChemDiv1_003498 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O23 mock treatment 285.4 93.5 0.49 280.5 92.8 0.48 0.6859 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 O24 mock treatment 117.2 -74.7 -0.39 108.1 -79.6 -0.41 -0.5682 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P01 compound treatment 278.8 86.9 0.45 285.6 97.9 0.51 0.6803 0.9983 1540792 ChemDiv1_003499 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P02 compound treatment 283.4 91.5 0.48 282.5 94.8 0.49 0.6859 0.9999 1443933 ChemDiv1_003500 COC(=O)c1ccc(OCC(O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P03 compound treatment 282.9 91.0 0.47 283.4 95.7 0.5 0.6873 0.9997 1972043 ChemDiv1_003501 COc1ccc(cc1)C(=O)OCCCN(C2=NS(=O)(=O)c3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P04 compound treatment 289.1 97.2 0.51 289.7 102.0 0.53 0.7334 0.9998 1605288 ChemDiv1_003502 CCOC(=O)c1c(NC(=O)c2cc3cc(Br)ccc3oc2=O)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P05 compound treatment 282.3 90.4 0.47 283.3 95.6 0.5 0.6847 0.9997 1151055 ChemDiv1_003503 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P06 compound treatment 280.8 88.9 0.46 284.8 97.1 0.5 0.6847 0.9991 1381848 ChemDiv1_003504 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccccc5c4=O)C(=O)CC(C)(C)C3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P07 compound treatment 283.3 91.4 0.48 285.3 97.6 0.51 0.6958 0.9995 1972044 ChemDiv1_003505 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P08 compound treatment 280.2 88.3 0.46 281.2 93.5 0.49 0.6693 0.9996 1972045 ChemDiv1_003506 [O-][N+](=O)c1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P09 compound treatment 282.6 90.7 0.47 277.5 89.8 0.47 0.6645 1.0 1467938 ChemDiv1_003507 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P10 compound treatment 282.0 90.1 0.47 286.2 98.5 0.51 0.6943 0.9991 1611605 ChemDiv1_003508 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c3cccc(Oc4ccccc4)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P11 compound treatment 285.2 93.3 0.49 278.9 91.2 0.47 0.6793 0.9999 1972046 ChemDiv1_003509 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P12 compound treatment 280.3 88.4 0.46 284.5 96.8 0.5 0.6818 0.9991 1686944 ChemDiv1_003510 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2Cl)C(=O)Nc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P13 compound treatment 282.9 91.0 0.47 285.9 98.2 0.51 0.6965 0.9993 1736462 ChemDiv1_003511 COC(=O)CN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P14 compound treatment 283.9 92.0 0.48 284.1 96.4 0.5 0.6936 0.9998 1972047 ChemDiv1_003512 O=C(CSc1ncn[nH]1)NC2CCCCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P15 compound treatment 286.5 94.6 0.49 283.6 95.9 0.5 0.7013 1.0 1278413 ChemDiv1_003513 Cc1cc(C)n(n1)c2cc(C)nc(NS(=O)(=O)c3ccccc3Cl)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P16 compound treatment 281.2 89.3 0.47 282.4 94.7 0.49 0.6774 0.9996 1972048 ChemDiv1_003514 CC(C)OCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P17 compound treatment 282.9 91.0 0.47 283.6 95.9 0.5 0.6881 0.9997 1972049 ChemDiv1_003515 CCNc1nc(NC(C)C)nc(OCCOC(=O)c2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P18 compound treatment 281.5 89.6 0.47 280.5 92.8 0.48 0.6715 0.9999 1124611 ChemDiv1_003516 O=C(N1N=C(CC1c2ccc3OCOc3c2)c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P19 compound treatment 280.7 88.8 0.46 278.5 90.8 0.47 0.6612 1.0 1972050 ChemDiv1_003517 CCNc1nc(NC(C)C)nc(SCCOc2ccc(C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P20 compound treatment 281.7 89.8 0.47 284.2 96.5 0.5 0.6858 0.9994 1157509 ChemDiv1_003518 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(OCc3ccccc3)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P21 compound treatment 278.3 86.4 0.45 279.5 91.8 0.48 0.656 0.9996 1568401 ChemDiv1_003519 COc1cc(C)nc(n1)N(Cc2ccccc2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P22 compound treatment 282.2 90.3 0.47 280.7 93.0 0.48 0.6748 0.9999 1972051 ChemDiv1_003520 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(F)cc3)C)ccc1OCc4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P23 mock treatment 283.4 91.5 0.48 283.1 95.4 0.5 0.6881 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.596 P24 mock treatment 106.6 -85.3 -0.44 105.0 -82.7 -0.43 -0.6187 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A01 compound treatment 343.6 150.0 0.78 342.9 156.0 0.81 1.1256 0.9998 1972052 ChemDiv1_003521 COC(=O)c1cccc(c1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A02 compound treatment 278.5 84.8 0.44 283.3 96.2 0.5 0.6664 0.9981 1972053 ChemDiv1_003522 OCCN1CCN(CC1)c2ccc(cc2n3nc(c4ccccc4)c5ccccc5c3=O)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A03 compound treatment 286.8 93.1 0.49 282.6 95.5 0.5 0.6945 0.9999 1972054 ChemDiv1_003523 [O-][N+](=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A04 compound treatment 288.7 95.0 0.5 283.4 96.3 0.5 0.7044 1.0 1972055 ChemDiv1_003524 CN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccc(cc4)C(C)(C)C)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A05 compound treatment 282.3 88.6 0.46 282.8 95.7 0.5 0.6786 0.9993 1972056 ChemDiv1_003525 CC1CCC2C(C1)C(=O)N(C2=O)c3cc(Cl)ccc3O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A06 compound treatment 282.6 88.9 0.46 281.9 94.8 0.49 0.6764 0.9995 1141663 ChemDiv1_003526 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A07 compound treatment 280.9 87.2 0.46 286.0 98.9 0.51 0.6852 0.9982 1972057 ChemDiv1_003527 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(s4)[N+](=O)[O-])C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A08 compound treatment 279.8 86.1 0.45 283.1 96.0 0.5 0.6705 0.9986 1972058 ChemDiv1_003528 [O-][N+](=O)c1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A09 compound treatment 280.5 86.8 0.45 282.8 95.7 0.5 0.672 0.9989 1360827 ChemDiv1_003529 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccnc4)C(=O)Cc5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A10 compound treatment 275.4 81.7 0.43 280.4 93.3 0.48 0.6443 0.9979 1407185 ChemDiv1_003530 COc1cc(cc(OC)c1OC)C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A11 compound treatment 281.6 87.9 0.46 283.2 96.1 0.5 0.6775 0.9991 1972059 ChemDiv1_003531 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(cc4)[N+](=O)[O-])C(=O)Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A12 compound treatment 280.0 86.3 0.45 280.9 93.8 0.49 0.6631 0.9992 1483635 ChemDiv1_003532 CCN(CC)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A13 compound treatment 279.6 85.9 0.45 282.0 94.9 0.49 0.6657 0.9989 1741790 ChemDiv1_003533 CCOc1cc(ccc1O)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A14 compound treatment 280.3 86.6 0.45 283.5 96.4 0.5 0.6738 0.9987 1972060 ChemDiv1_003534 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A15 compound treatment 277.6 83.9 0.44 280.7 93.6 0.49 0.6535 0.9986 1310272 ChemDiv1_003535 COc1ccccc1C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A16 compound treatment 277.8 84.1 0.44 278.7 91.6 0.48 0.6469 0.9992 1947838 ChemDiv1_003536 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccs2)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A17 compound treatment 279.9 86.2 0.45 277.8 90.7 0.47 0.6514 0.9997 1972061 ChemDiv1_003537 COc1ccc(cc1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A18 compound treatment 280.0 86.3 0.45 278.0 90.9 0.47 0.6525 0.9997 1187227 ChemDiv1_003538 COc1ccc(cc1)C2=NN(C(C2)c3ccc(OC)c(OC)c3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A19 compound treatment 279.6 85.9 0.45 277.8 90.7 0.47 0.6503 0.9997 1691001 ChemDiv1_003539 COc1cccc(c1)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A20 compound treatment 279.3 85.6 0.45 277.7 90.6 0.47 0.6488 0.9997 1602615 ChemDiv1_003540 Cc1nc2sc(C(=O)c3ccc(Br)cc3)c(N)c2c(C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A21 compound treatment 280.7 87.0 0.45 276.7 89.6 0.47 0.6503 0.9999 1972062 ChemDiv1_003541 CN1C(=C(C(NC1=O)c2ccccc2C(F)(F)F)C(=O)OCCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A22 compound treatment 274.3 80.6 0.42 275.7 88.6 0.46 0.623 0.999 1972063 ChemDiv1_003542 Fc1ccc(cc1)c2nn3c(nnc3s2)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A23 mock treatment 281.6 87.9 0.46 280.0 92.9 0.48 0.6657 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 A24 mock treatment 78.6 -115.0 -0.6 77.6 -110.0 -0.57 -0.827 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B01 compound treatment 284.6 90.9 0.47 284.4 97.3 0.51 0.693 0.9995 1478825 ChemDiv1_003543 CC1(C)Cc2c(C#N)c(SCC(=O)c3ccccc3)nc(N4CCOCC4)c2CO1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B02 compound treatment 381.3 188.0 0.98 373.2 186.0 0.97 1.3761 1.0 1730423 ChemDiv1_003544 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Br)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B03 compound treatment 284.2 90.5 0.47 287.0 99.9 0.52 0.7011 0.9989 1369892 ChemDiv1_003545 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B04 compound treatment 280.9 87.2 0.46 282.3 95.2 0.49 0.6716 0.9991 1600020 ChemDiv1_003546 COc1ccc(cc1Br)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B05 compound treatment 280.9 87.2 0.46 285.3 98.2 0.51 0.6826 0.9984 1323604 ChemDiv1_003547 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B06 compound treatment 280.8 87.1 0.45 282.6 95.5 0.5 0.6723 0.999 1385707 ChemDiv1_003548 CC(C)(C)C1CCC(CC1)C(=O)On2c(nc3ccccc3c2=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B07 compound treatment 282.1 88.4 0.46 282.0 94.9 0.49 0.6749 0.9994 1469351 ChemDiv1_003549 COc1cc(cc(OC)c1OC)C2Nc3cc(C)ccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B08 compound treatment 283.8 90.1 0.47 283.9 96.8 0.5 0.6882 0.9994 1972064 ChemDiv1_003550 CCOc1ccc(Br)cc1C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B09 compound treatment 283.4 89.7 0.47 279.9 92.8 0.48 0.672 0.9999 1374056 ChemDiv1_003551 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B10 compound treatment 281.4 87.7 0.46 282.0 94.9 0.49 0.6723 0.9993 1972065 ChemDiv1_003552 CCCC1=C(C(C(=C(N)O1)C#N)c2cccnc2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B11 compound treatment 279.6 85.9 0.45 277.1 90.0 0.47 0.6477 0.9998 1638651 ChemDiv1_003553 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(COc5ccccn5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B12 compound treatment 280.2 86.5 0.45 283.1 96.0 0.5 0.672 0.9988 1972066 ChemDiv1_003554 COC(=O)C1=C(N)OC2=C(C1c3cccc(Br)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B13 compound treatment 284.6 90.9 0.47 283.4 96.3 0.5 0.6893 0.9996 1454062 ChemDiv1_003555 COc1ccc(cc1CSc2nc3ccccc3s2)C4Nc5ccccc5C(=O)N4c6ccc(F)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B14 compound treatment 277.0 83.3 0.43 280.3 93.2 0.48 0.6499 0.9985 1187408 ChemDiv1_003556 CCOc1ccc(cc1OCC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B15 compound treatment 282.6 88.9 0.46 283.3 96.2 0.5 0.6815 0.9993 1605039 ChemDiv1_003557 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B16 compound treatment 280.6 86.9 0.45 277.5 90.4 0.47 0.6529 0.9998 1972067 ChemDiv1_003558 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(cc3)C4C(=C(N)OC5=C4C(=O)CC(C)(C)C5)C#N)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B17 compound treatment 286.2 92.5 0.48 282.6 95.5 0.5 0.6923 0.9999 1508675 ChemDiv1_003559 COc1ccc(cc1COc2ccccc2F)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B18 compound treatment 286.1 92.4 0.48 281.3 94.2 0.49 0.6871 1.0 1972068 ChemDiv1_003560 COc1ccc(cc1COc2ccc([N+](=O)[O-])c(C)c2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B19 compound treatment 276.7 83.0 0.43 279.4 92.3 0.48 0.6455 0.9987 1972069 ChemDiv1_003561 COc1ccc(cc1COc2c(C)cccc2C)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B20 compound treatment 275.9 82.2 0.43 278.3 91.2 0.47 0.6385 0.9988 1972070 ChemDiv1_003562 Cc1nn(c2OC(=C(C#N)C3(C(=O)Nc4ccc(Br)cc43)c12)N)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B21 compound treatment 263.0 69.3 0.36 263.5 76.4 0.4 0.5365 0.9989 1972071 ChemDiv1_003563 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3[N+](=O)[O-])C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B22 compound treatment 282.3 88.6 0.46 280.6 93.5 0.49 0.6705 0.9997 1371861 ChemDiv1_003564 CCOC(=O)C1=C(N)Oc2c(C1c3c(F)cccc3Cl)c(=O)oc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B23 mock treatment 281.4 87.7 0.46 276.1 89.0 0.46 0.6507 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 B24 mock treatment 83.2 -110.0 -0.58 79.1 -108.0 -0.56 -0.8045 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C01 compound treatment 285.7 92.0 0.48 287.4 100.0 0.52 0.7081 0.9992 1783858 ChemDiv1_003565 [O-][N+](=O)c1c(Sc2ncnc3[nH]cnc23)ccc4nsnc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C02 compound treatment 281.4 87.7 0.46 283.0 95.9 0.5 0.676 0.9991 1924205 ChemDiv1_003566 Cc1ccc(cc1C)c2nn(c3cc(ccc3[N+](=O)[O-])N4CCN(CCO)CC4)c(=O)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C03 compound treatment 283.6 89.9 0.47 286.4 99.3 0.52 0.6966 0.9989 1741741 ChemDiv1_003567 COc1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C04 compound treatment 277.0 83.3 0.43 284.5 97.4 0.51 0.6653 0.9971 1972072 ChemDiv1_003568 CC(C)(C)c1ccc(Oc2c(oc3cc(OCC(=O)O)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C05 compound treatment 285.8 92.1 0.48 283.4 96.3 0.5 0.6937 0.9998 1972073 ChemDiv1_003569 CC1CCC2C(C1)C(=O)N(CNc3ccc(Br)cc3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C06 compound treatment 280.2 86.5 0.45 283.9 96.8 0.5 0.6749 0.9985 1429536 ChemDiv1_003570 CCCOc1ccc(cc1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C07 compound treatment 280.5 86.8 0.45 283.8 96.7 0.5 0.6756 0.9987 1783502 ChemDiv1_003571 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(s4)[N+](=O)[O-])C(=O)Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C08 compound treatment 277.6 83.9 0.44 281.4 94.3 0.49 0.6561 0.9984 1972074 ChemDiv1_003572 Fc1ccccc1c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C09 compound treatment 277.2 83.5 0.44 280.4 93.3 0.48 0.651 0.9986 1333813 ChemDiv1_003573 CN(C)c1ccc(cc1)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C10 compound treatment 276.7 83.0 0.43 279.8 92.7 0.48 0.6469 0.9986 1385408 ChemDiv1_003574 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C11 compound treatment 278.0 84.3 0.44 282.1 95.0 0.49 0.6602 0.9983 1972075 ChemDiv1_003575 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C12 compound treatment 279.9 86.2 0.45 281.4 94.3 0.49 0.6646 0.9991 1463317 ChemDiv1_003576 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C13 compound treatment 280.2 86.5 0.45 282.8 95.7 0.5 0.6709 0.9988 1972076 ChemDiv1_003577 CCCOc1cccc(c1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C14 compound treatment 278.5 84.8 0.44 280.8 93.7 0.49 0.6572 0.9989 1972077 ChemDiv1_003578 COc1ccc(cc1[N+](=O)[O-])C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C15 compound treatment 280.7 87.0 0.45 280.9 93.8 0.49 0.6657 0.9994 1941658 ChemDiv1_003579 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C16 compound treatment 278.4 84.7 0.44 278.0 90.9 0.47 0.6466 0.9994 1972078 ChemDiv1_003580 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C17 compound treatment 280.3 86.6 0.45 284.5 97.4 0.51 0.6775 0.9984 1169887 ChemDiv1_003581 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccco3)Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C18 compound treatment 276.1 82.4 0.43 278.0 90.9 0.47 0.6381 0.9989 1137529 ChemDiv1_003582 COc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccccc4)c5ccccc5)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C19 compound treatment 276.8 83.1 0.43 279.2 92.1 0.48 0.6451 0.9988 1294475 ChemDiv1_003583 COc1ccc(C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C20 compound treatment 285.9 92.2 0.48 280.0 92.9 0.48 0.6816 1.0 1972079 ChemDiv1_003584 Cc1cc(c(C#N)c(SCC(=O)c2ccc(cc2)[N+](=O)[O-])n1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C21 compound treatment 276.9 83.2 0.43 275.3 88.2 0.46 0.6311 0.9996 1494965 ChemDiv1_003585 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C22 compound treatment 280.8 87.1 0.45 280.2 93.1 0.48 0.6635 0.9995 1972080 ChemDiv1_003586 Clc1ccc(cc1)c2nnc3sc(nn23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C23 mock treatment 285.3 91.6 0.48 275.3 88.2 0.46 0.6621 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 C24 mock treatment 83.4 -110.0 -0.58 80.2 -107.0 -0.56 -0.7997 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D01 compound treatment 285.7 92.0 0.48 285.6 98.5 0.51 0.7014 0.9995 1513188 ChemDiv1_003587 CC1(C)Cc2c(C#N)c(SCC(=O)c3ccc(Br)cc3)nc(N4CCOCC4)c2CO1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D02 compound treatment 287.8 94.1 0.49 284.6 97.5 0.51 0.7055 0.9999 1949074 ChemDiv1_003588 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Br)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D03 compound treatment 282.6 88.9 0.46 287.6 100.0 0.52 0.6974 0.9983 1972081 ChemDiv1_003589 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D04 compound treatment 282.3 88.6 0.46 280.7 93.6 0.49 0.6709 0.9997 1289721 ChemDiv1_003590 Fc1ccccc1c2nc3ccccc3c(=O)n2OC(=O)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D05 compound treatment 284.5 90.8 0.47 284.0 96.9 0.5 0.6911 0.9995 1151856 ChemDiv1_003591 CCN(CC)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D06 compound treatment 282.8 89.1 0.46 284.4 97.3 0.51 0.6863 0.9991 1634062 ChemDiv1_003592 Cc1cccc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4c(F)cccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D07 compound treatment 288.2 94.5 0.49 290.0 103.0 0.53 0.7268 0.9992 1273329 ChemDiv1_003593 Brc1cccc(c1)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D08 compound treatment 295.9 102.0 0.53 303.4 116.0 0.6 0.8045 0.998 1121346 ChemDiv1_003594 CC1=C(C(C(=C(S)N1)C#N)c2cccs2)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D09 compound treatment 283.8 90.1 0.47 285.7 98.6 0.51 0.6948 0.9991 1295486 ChemDiv1_003595 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D10 compound treatment 263.6 69.9 0.36 262.9 75.8 0.39 0.5365 0.9993 1972082 ChemDiv1_003596 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3[N+](=O)[O-])C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D11 compound treatment 283.7 90.0 0.47 281.6 94.5 0.49 0.6794 0.9997 1262591 ChemDiv1_003597 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(COc5ccccc5F)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D12 compound treatment 278.4 84.7 0.44 285.0 97.9 0.51 0.6723 0.9975 1972083 ChemDiv1_003598 CCCCOc1ccc(cc1OC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D13 compound treatment 280.8 87.1 0.45 285.9 98.8 0.51 0.6845 0.9981 1420502 ChemDiv1_003599 CCOC(=O)c1ccccc1OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D14 compound treatment 279.6 85.9 0.45 280.3 93.2 0.48 0.6595 0.9993 1590080 ChemDiv1_003600 COc1cc(ccc1OC(C)C)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D15 compound treatment 281.1 87.4 0.46 281.7 94.6 0.49 0.6701 0.9993 1926561 ChemDiv1_003601 COc1ccc(cc1Cn2cc(cn2)[N+](=O)[O-])C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D16 compound treatment 282.4 88.7 0.46 286.4 99.3 0.52 0.6922 0.9985 1972084 ChemDiv1_003602 COc1ccc(cc1COc2ccccc2Br)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D17 compound treatment 289.3 95.6 0.5 282.1 95.0 0.49 0.7019 1.0 1628129 ChemDiv1_003603 COc1ccc(cc1COc2cc(C)c(Cl)cc2C(C)C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D18 compound treatment 283.9 90.2 0.47 281.1 94.0 0.49 0.6783 0.9998 1972085 ChemDiv1_003604 COc1ccc(cc1COc2cccc(Cl)c2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D19 compound treatment 280.3 86.6 0.45 280.3 93.2 0.48 0.662 0.9994 1293465 ChemDiv1_003605 COc1cc(cc(OC)c1OC)C2Nc3ccccc3C(=O)N2c4cccc5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D20 compound treatment 282.4 88.7 0.46 281.3 94.2 0.49 0.6735 0.9996 1203913 ChemDiv1_003606 Cc1cc2OC(=C(C#N)C3(C(=O)Nc4ccc(Br)cc43)c2c(=O)o1)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D21 compound treatment 280.4 86.7 0.45 280.5 93.4 0.49 0.6631 0.9994 1403609 ChemDiv1_003607 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(O)cc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D22 compound treatment 283.5 89.8 0.47 279.0 91.9 0.48 0.6691 1.0 1437882 ChemDiv1_003608 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D23 mock treatment 282.4 88.7 0.46 281.1 94.0 0.49 0.6727 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 D24 mock treatment 80.9 -113.0 -0.59 81.1 -106.0 -0.55 -0.8057 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E01 compound treatment 290.5 96.8 0.51 290.5 103.0 0.54 0.7372 0.9995 1913169 ChemDiv1_003609 COc1cc(cc(OC)c1OC)C2NC(Cc3c2[nH]c4ccccc34)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E02 compound treatment 286.1 92.4 0.48 287.4 100.0 0.52 0.7095 0.9992 1972086 ChemDiv1_003610 Cc1cc(C)n(n1)c2cc(C)nc(n2)n3nc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E03 compound treatment 286.2 92.5 0.48 281.6 94.5 0.49 0.6886 1.0 1493314 ChemDiv1_003611 CCOC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E04 compound treatment 284.5 90.8 0.47 283.0 95.9 0.5 0.6875 0.9997 1267526 ChemDiv1_003612 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)COc3ccc4ccccc4c3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E05 compound treatment 281.5 87.8 0.46 284.2 97.1 0.5 0.6808 0.9988 1972087 ChemDiv1_003613 CC1CCC2C(C1)C(=O)N(CNc3ccc(Oc4ccc(Br)cc4)cc3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E06 compound treatment 280.1 86.4 0.45 286.6 99.5 0.52 0.6845 0.9977 1463008 ChemDiv1_003614 CCOc1ccc(cc1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E07 compound treatment 283.2 89.5 0.47 286.2 99.1 0.52 0.6944 0.9988 1494841 ChemDiv1_003615 COc1cc(cc(OC)c1OC)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E08 compound treatment 280.5 86.8 0.45 285.5 98.4 0.51 0.6819 0.9982 1504968 ChemDiv1_003616 COc1ccc(Cl)cc1C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E09 compound treatment 278.6 84.9 0.44 283.6 96.5 0.5 0.6679 0.9981 1446706 ChemDiv1_003617 COc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E10 compound treatment 280.7 87.0 0.45 283.6 96.5 0.5 0.6756 0.9988 1386453 ChemDiv1_003618 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E11 compound treatment 283.4 89.7 0.47 281.8 94.7 0.49 0.679 0.9997 1612209 ChemDiv1_003619 Cc1ccc(o1)C2N(C(=O)Cc3ccc(Cl)cc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E12 compound treatment 280.7 87.0 0.45 285.1 98.0 0.51 0.6812 0.9984 1618927 ChemDiv1_003620 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4c(F)cccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E13 compound treatment 277.0 83.3 0.43 279.8 92.7 0.48 0.648 0.9987 1267036 ChemDiv1_003621 CCCOc1ccc(cc1OC)C2N(C(=O)CC)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E14 compound treatment 281.1 87.4 0.46 282.9 95.8 0.5 0.6745 0.999 1207726 ChemDiv1_003622 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E15 compound treatment 278.7 85.0 0.44 282.0 94.9 0.49 0.6624 0.9986 1255600 ChemDiv1_003623 COc1cc(ccc1OCc2ccccc2)C3N(C(=O)C)c4ccccc4NC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E16 compound treatment 275.6 81.9 0.43 283.3 96.2 0.5 0.6557 0.997 1972088 ChemDiv1_003624 Cc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E17 compound treatment 281.7 88.0 0.46 281.5 94.4 0.49 0.6716 0.9995 1972089 ChemDiv1_003625 CCCCCC(=O)N1C(C2=C(CC(CC2=O)c3ccco3)Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E18 compound treatment 281.2 87.5 0.46 279.6 92.5 0.48 0.6628 0.9997 1675096 ChemDiv1_003626 Cc1ccc(cc1)N2C(=O)CC(Sc3nc4ccccc4o3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E19 compound treatment 280.1 86.4 0.45 280.0 92.9 0.48 0.6602 0.9994 1666247 ChemDiv1_003627 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(O)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E20 compound treatment 280.6 86.9 0.45 282.3 95.2 0.49 0.6705 0.9991 1463989 ChemDiv1_003628 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)N)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E21 compound treatment 280.0 86.3 0.45 280.3 93.2 0.48 0.6609 0.9993 1183030 ChemDiv1_003629 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Cl)c(O)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E22 compound treatment 278.3 84.6 0.44 282.2 95.1 0.49 0.6616 0.9984 1972090 ChemDiv1_003630 COc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E23 mock treatment 280.3 86.6 0.45 282.6 95.5 0.5 0.6705 0.9989 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 E24 mock treatment 82.5 -111.0 -0.58 79.6 -108.0 -0.56 -0.8053 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F01 compound treatment 286.4 92.7 0.48 288.6 101.0 0.53 0.715 0.9991 1641369 ChemDiv1_003631 CCOC(=O)c1sc2nc(N3CCOCC3)c4COC(C)(C)Cc4c2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F02 compound treatment 303.6 110.0 0.57 296.9 110.0 0.57 0.809 1.0 1641270 ChemDiv1_003632 CCOc1c(Br)cc(C=c2sc3nc4ccccc4n3c2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F03 compound treatment 284.4 90.7 0.47 280.6 93.5 0.49 0.6783 0.9999 1972091 ChemDiv1_003633 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(OC)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F04 compound treatment 288.1 94.4 0.49 286.4 99.3 0.52 0.7132 0.9997 1219588 ChemDiv1_003634 CC(C)(C)c1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F05 compound treatment 280.5 86.8 0.45 287.3 100.0 0.52 0.6885 0.9976 1609774 ChemDiv1_003635 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F06 compound treatment 293.5 99.8 0.52 296.6 109.0 0.57 0.7706 0.999 1685670 ChemDiv1_003636 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F07 compound treatment 281.3 87.6 0.46 284.7 97.6 0.51 0.6819 0.9987 1948397 ChemDiv1_003637 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F08 compound treatment 302.4 109.0 0.57 304.5 117.0 0.61 0.8325 0.9993 1622120 ChemDiv1_003638 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2ccsc2)S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F09 compound treatment 287.6 93.9 0.49 284.1 97.0 0.5 0.7029 0.9999 1972092 ChemDiv1_003639 COc1ccc(cc1COc2cc(C)c(Cl)cc2C(C)C)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F10 compound treatment 281.6 87.9 0.46 282.8 95.7 0.5 0.676 0.9992 1972093 ChemDiv1_003640 COCCOC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F11 compound treatment 286.2 92.5 0.48 284.7 97.6 0.51 0.7 0.9997 1623119 ChemDiv1_003641 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc5n(C)c6ccccc6c5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F12 compound treatment 282.0 88.3 0.46 284.8 97.7 0.51 0.6848 0.9988 1972094 ChemDiv1_003642 Cc1nn(c(Cl)c1C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F13 compound treatment 286.5 92.8 0.48 284.5 97.4 0.51 0.7003 0.9998 1533547 ChemDiv1_003643 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4c6ccc(F)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F14 compound treatment 275.9 82.2 0.43 280.3 93.2 0.48 0.6458 0.9982 1972095 ChemDiv1_003644 COCCOC(=O)C1=C(N)Oc2c(C1c3ccncc3)c(=O)oc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F15 compound treatment 277.2 83.5 0.44 282.9 95.8 0.5 0.6602 0.9978 1199095 ChemDiv1_003645 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F16 compound treatment 282.8 89.1 0.46 287.2 100.0 0.52 0.6966 0.9984 1972096 ChemDiv1_003646 COc1ccc(cc1COc2ccccc2[N+](=O)[O-])C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F17 compound treatment 282.9 89.2 0.47 284.8 97.7 0.51 0.6882 0.9991 1554799 ChemDiv1_003647 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4Cc6ccco6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F18 compound treatment 279.8 86.1 0.45 284.4 97.3 0.51 0.6753 0.9983 1972097 ChemDiv1_003648 COc1ccc(cc1COc2ccc(Cl)cc2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F19 compound treatment 280.7 87.0 0.45 282.4 95.3 0.5 0.6712 0.9991 1210982 ChemDiv1_003649 CCN(CC)CCN1C(Nc2ccccc2C1=O)c3cc(OC)c(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F20 compound treatment 279.4 85.7 0.45 280.1 93.0 0.48 0.658 0.9992 1619977 ChemDiv1_003650 NC1=C(C#N)C2(C(=O)Nc3ccc(Br)cc32)C4=C(CCCC4=O)O1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F21 compound treatment 277.2 83.5 0.44 281.3 94.2 0.49 0.6543 0.9983 1503763 ChemDiv1_003651 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F22 compound treatment 286.3 92.6 0.48 282.3 95.2 0.49 0.6915 0.9999 1402798 ChemDiv1_003652 NS(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F23 mock treatment 283.2 89.5 0.47 282.7 95.6 0.5 0.6816 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 F24 mock treatment 79.7 -114.0 -0.59 79.9 -107.0 -0.56 -0.8145 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G01 compound treatment 285.3 91.6 0.48 285.3 98.2 0.51 0.6989 0.9995 1323011 ChemDiv1_003653 Clc1ccc(cc1Cl)n2c(CSc3ncnc4[nH]cnc34)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G02 compound treatment 284.2 90.5 0.47 282.5 95.4 0.5 0.6845 0.9997 1949436 ChemDiv1_003654 FC(F)(F)c1ccc(Cl)c(NC(=O)C2COc3ccccc3O2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G03 compound treatment 283.7 90.0 0.47 286.0 98.9 0.51 0.6955 0.999 1972098 ChemDiv1_003655 CC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G04 compound treatment 279.3 85.6 0.45 283.1 96.0 0.5 0.6686 0.9985 1269765 ChemDiv1_003656 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G05 compound treatment 282.3 88.6 0.46 285.1 98.0 0.51 0.6871 0.9988 1531225 ChemDiv1_003657 COc1ccc(cc1)c2cc(C(=O)Nc3ccccc3OC)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G06 compound treatment 282.3 88.6 0.46 282.5 95.4 0.5 0.6775 0.9994 1972099 ChemDiv1_003658 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OCCSCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G07 compound treatment 281.2 87.5 0.46 287.4 100.0 0.52 0.6915 0.9978 1972100 ChemDiv1_003659 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G08 compound treatment 281.5 87.8 0.46 282.9 95.8 0.5 0.676 0.9991 1588762 ChemDiv1_003660 COc1cccc(CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G09 compound treatment 286.0 92.3 0.48 284.2 97.1 0.5 0.6974 0.9997 1782662 ChemDiv1_003661 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccc(c4)[N+](=O)[O-])C(=O)Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G10 compound treatment 284.5 90.8 0.47 287.4 100.0 0.52 0.7036 0.9989 1972101 ChemDiv1_003662 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(cc4Cl)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G11 compound treatment 279.1 85.4 0.45 284.3 97.2 0.51 0.6723 0.998 1972102 ChemDiv1_003663 COc1cc(cc(OC)c1OC)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G12 compound treatment 283.1 89.4 0.47 283.7 96.6 0.5 0.6849 0.9993 1972103 ChemDiv1_003664 COc1ccc(cc1OC)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G13 compound treatment 281.4 87.7 0.46 283.8 96.7 0.5 0.679 0.9989 1972104 ChemDiv1_003665 CCCOc1ccc(cc1OC)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G14 compound treatment 278.3 84.6 0.44 283.6 96.5 0.5 0.6668 0.998 1698962 ChemDiv1_003666 COc1ccc(cc1OC)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G15 compound treatment 277.4 83.7 0.44 285.9 98.8 0.51 0.6719 0.9968 1972105 ChemDiv1_003667 CC(C)Oc1ccc(cc1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G16 compound treatment 281.1 87.4 0.46 280.7 93.6 0.49 0.6665 0.9995 1289089 ChemDiv1_003668 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G17 compound treatment 280.8 87.1 0.45 285.8 98.7 0.51 0.6841 0.9982 1972106 ChemDiv1_003669 COc1ccc(cc1OC)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G18 compound treatment 279.0 85.3 0.45 278.1 91.0 0.47 0.6492 0.9995 1328822 ChemDiv1_003670 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(C)cc(C)c3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G19 compound treatment 280.1 86.4 0.45 278.2 91.1 0.47 0.6536 0.9997 1947407 ChemDiv1_003671 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G20 compound treatment 280.8 87.1 0.45 274.4 87.3 0.45 0.6422 1.0 1332142 ChemDiv1_003672 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G21 compound treatment 279.2 85.5 0.45 273.7 86.6 0.45 0.6337 1.0 1947503 ChemDiv1_003673 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(Cl)c(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G22 compound treatment 280.8 87.1 0.45 277.5 90.4 0.47 0.6536 0.9999 1332974 ChemDiv1_003674 COC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G23 mock treatment 280.0 86.3 0.45 284.2 97.1 0.5 0.6753 0.9984 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 G24 mock treatment 80.6 -113.0 -0.59 77.8 -109.0 -0.57 -0.8189 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H01 compound treatment 283.8 90.1 0.47 287.3 100.0 0.52 0.7007 0.9987 1972107 ChemDiv1_003675 CCOC(=O)c1c(NC(=O)CN2C(=O)C3CC=C(Cl)CC3C2=O)sc4CCCCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H02 compound treatment 283.0 89.3 0.47 282.1 95.0 0.49 0.6786 0.9996 1138082 ChemDiv1_003676 COc1ccc(cc1)C(=O)Oc2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H03 compound treatment 285.5 91.8 0.48 287.1 100.0 0.52 0.7062 0.9992 1597317 ChemDiv1_003677 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H04 compound treatment 285.1 91.4 0.48 282.8 95.7 0.5 0.6889 0.9998 1972108 ChemDiv1_003678 Cc1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H05 compound treatment 279.2 85.5 0.45 282.6 95.5 0.5 0.6664 0.9986 1972109 ChemDiv1_003679 COc1ccc(/C=C(\C#N)/C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H06 compound treatment 281.3 87.6 0.46 284.5 97.4 0.51 0.6812 0.9987 1275145 ChemDiv1_003680 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)nc(OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H07 compound treatment 282.2 88.5 0.46 285.3 98.2 0.51 0.6874 0.9988 1972110 ChemDiv1_003681 CSc1nnc(o1)c2ccc(NC(=S)N3CCCCC3)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H08 compound treatment 325.0 131.0 0.69 326.1 139.0 0.72 0.9953 0.9996 1294556 ChemDiv1_003682 CC1=C(C(C(=C(S)N1)C#N)c2cccnc2)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H09 compound treatment 285.9 92.2 0.48 286.8 99.7 0.52 0.7066 0.9993 1631992 ChemDiv1_003683 COc1ccc(cc1CSc2nc3ccccc3s2)C4Nc5ccccc5C(=O)N4c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H10 compound treatment 286.9 93.2 0.49 282.9 95.8 0.5 0.6959 0.9999 1972111 ChemDiv1_003684 COCCOC(=O)C1=C(N)OC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H11 compound treatment 283.6 89.9 0.47 290.9 104.0 0.54 0.7132 0.9976 1304978 ChemDiv1_003685 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H12 compound treatment 285.1 91.4 0.48 286.5 99.4 0.52 0.7025 0.9992 1972112 ChemDiv1_003686 Cc1nn(c(Cl)c1C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H13 compound treatment 277.8 84.1 0.44 281.1 94.0 0.49 0.6558 0.9986 1738017 ChemDiv1_003687 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4c6ccc(Cl)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H14 compound treatment 298.6 105.0 0.55 307.8 121.0 0.63 0.8306 0.9977 1972113 ChemDiv1_003688 Cc1cc(c2c(N)c(sc2n1)C(=O)c3ccc(Cl)s3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H15 compound treatment 281.8 88.1 0.46 284.3 97.2 0.51 0.6823 0.9989 1506926 ChemDiv1_003689 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4c6ccc(C)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H16 compound treatment 285.2 91.5 0.48 285.5 98.4 0.51 0.6992 0.9994 1972114 ChemDiv1_003690 COc1ccc(cc1COc2ccccc2[N+](=O)[O-])C3C(=C(N)Oc4n[nH]c(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H17 compound treatment 287.8 94.1 0.49 289.5 102.0 0.53 0.7235 0.9992 1741585 ChemDiv1_003691 COc1ccc(cc1COc2ccccc2F)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H18 compound treatment 279.5 85.8 0.45 281.6 94.5 0.49 0.6639 0.9989 1972115 ChemDiv1_003692 COC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H19 compound treatment 283.0 89.3 0.47 277.9 90.8 0.47 0.6632 1.0 1585328 ChemDiv1_003693 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(CSc4ccccn4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H20 compound treatment 279.5 85.8 0.45 287.9 101.0 0.52 0.687 0.9969 1972116 ChemDiv1_003694 COc1ccc(NC(=O)CSc2nc(C)cc(c2C#N)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H21 compound treatment 301.7 108.0 0.56 307.2 120.0 0.62 0.8398 0.9987 1940201 ChemDiv1_003695 Oc1ccccc1C2CC(=NN2c3ccc(cc3)[N+](=O)[O-])c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H22 compound treatment 276.7 83.0 0.43 280.6 93.5 0.49 0.6499 0.9984 1783090 ChemDiv1_003696 OC(=O)CCc1nc2ccccc2[nH]c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H23 mock treatment 281.9 88.2 0.46 281.1 94.0 0.49 0.6709 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 H24 mock treatment 81.6 -112.0 -0.58 74.2 -113.0 -0.59 -0.8284 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I01 compound treatment 286.0 92.3 0.48 281.8 94.7 0.49 0.6886 0.9999 1972117 ChemDiv1_003697 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)Nc4cccc5cccnc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I02 compound treatment 287.9 94.2 0.49 287.5 100.0 0.52 0.7165 0.9996 1942266 ChemDiv1_003698 FC(F)(F)c1ccc(Cl)c(NC(=O)CCN2C(=O)c3ccccc3C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I03 compound treatment 281.2 87.5 0.46 281.7 94.6 0.49 0.6705 0.9993 1398617 ChemDiv1_003699 Brc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I04 compound treatment 282.4 88.7 0.46 287.7 101.0 0.52 0.697 0.9982 1117622 ChemDiv1_003700 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I05 compound treatment 284.4 90.7 0.47 282.5 95.4 0.5 0.6852 0.9997 1735688 ChemDiv1_003701 CN(C)c1ccc(cc1)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I06 compound treatment 285.0 91.3 0.48 287.2 100.0 0.52 0.7047 0.999 1972118 ChemDiv1_003702 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I07 compound treatment 281.5 87.8 0.46 289.0 102.0 0.53 0.6984 0.9974 1686952 ChemDiv1_003703 COc1cc(cc(OC)c1OC)C2N(C(=O)C(C)C)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I08 compound treatment 286.2 92.5 0.48 282.1 95.0 0.49 0.6904 0.9999 1149956 ChemDiv1_003704 COc1cc(OC)cc(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I09 compound treatment 281.8 88.1 0.46 287.4 100.0 0.52 0.6937 0.998 1947742 ChemDiv1_003705 CN(C)/C=C\1/C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I10 compound treatment 280.6 86.9 0.45 281.5 94.4 0.49 0.6676 0.9992 1972119 ChemDiv1_003706 COc1ccc(C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I11 compound treatment 280.2 86.5 0.45 280.4 93.3 0.48 0.662 0.9994 1488499 ChemDiv1_003707 CN(C)c1ccc(cc1)C2N(C(=O)c3ccc(F)cc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I12 compound treatment 283.1 89.4 0.47 286.3 99.2 0.52 0.6944 0.9988 1712333 ChemDiv1_003708 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Br)ccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I13 compound treatment 281.6 87.9 0.46 284.5 97.4 0.51 0.6823 0.9988 1152977 ChemDiv1_003709 COc1ccc(OC)c(c1)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I14 compound treatment 282.7 89.0 0.46 286.7 99.6 0.52 0.6944 0.9985 1166729 ChemDiv1_003710 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I15 compound treatment 281.4 87.7 0.46 280.6 93.5 0.49 0.6672 0.9996 1640599 ChemDiv1_003711 CC(=O)Oc1cccc(c1)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I16 compound treatment 297.2 104.0 0.54 305.4 118.0 0.61 0.8166 0.9979 1972120 ChemDiv1_003712 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I17 compound treatment 282.4 88.7 0.46 281.5 94.4 0.49 0.6742 0.9996 1425826 ChemDiv1_003713 CCN(CC)c1ccc(cc1)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I18 compound treatment 284.7 91.0 0.47 283.6 96.5 0.5 0.6904 0.9996 1218259 ChemDiv1_003714 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(ccc3C#N)C4CC4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I19 compound treatment 283.3 89.6 0.47 284.0 96.9 0.5 0.6867 0.9993 1972121 ChemDiv1_003715 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(ccc5Cl)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I20 compound treatment 279.6 85.9 0.45 284.7 97.6 0.51 0.6756 0.9981 1338023 ChemDiv1_003716 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(Cl)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I21 compound treatment 282.1 88.4 0.46 278.2 91.1 0.47 0.661 0.9999 1948370 ChemDiv1_003717 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)cc2)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I22 compound treatment 281.3 87.6 0.46 281.6 94.5 0.49 0.6705 0.9994 1259634 ChemDiv1_003718 COC(=O)CCSc1nc2sc3CCCc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I23 mock treatment 283.2 89.5 0.47 281.0 93.9 0.49 0.6753 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 I24 mock treatment 80.0 -114.0 -0.59 76.8 -110.0 -0.57 -0.8248 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J01 compound treatment 283.8 90.1 0.47 284.5 97.4 0.51 0.6904 0.9993 1530128 ChemDiv1_003719 CCN(CC)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J02 compound treatment 285.5 91.8 0.48 286.0 98.9 0.51 0.7022 0.9994 1972122 ChemDiv1_003720 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J03 compound treatment 286.5 92.8 0.48 282.9 95.8 0.5 0.6945 0.9999 1972123 ChemDiv1_003721 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J04 compound treatment 285.3 91.6 0.48 282.7 95.6 0.5 0.6893 0.9998 1506469 ChemDiv1_003722 Cc1cccc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J05 compound treatment 283.5 89.8 0.47 282.3 95.2 0.49 0.6812 0.9996 1291803 ChemDiv1_003723 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccoc3)c4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J06 compound treatment 282.1 88.4 0.46 281.8 94.7 0.49 0.6742 0.9995 1528862 ChemDiv1_003724 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J07 compound treatment 284.2 90.5 0.47 286.4 99.3 0.52 0.6988 0.999 1654231 ChemDiv1_003725 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N)C(=O)N(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J08 compound treatment 288.4 94.7 0.49 288.8 102.0 0.53 0.7232 0.9994 1348892 ChemDiv1_003726 NC1=C(C#N)C(c2cccc(OCc3ccccc3)c2)c4c(O1)c5ccccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J09 compound treatment 283.3 89.6 0.47 286.4 99.3 0.52 0.6955 0.9988 1117948 ChemDiv1_003727 CCOC(=O)c1ccccc1OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J10 compound treatment 273.2 79.5 0.41 279.4 92.3 0.48 0.6325 0.9974 1972124 ChemDiv1_003728 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3[N+](=O)[O-])C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J11 compound treatment 281.1 87.4 0.46 287.4 100.0 0.52 0.6911 0.9978 1583931 ChemDiv1_003729 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J12 compound treatment 282.2 88.5 0.46 285.8 98.7 0.51 0.6893 0.9986 1180588 ChemDiv1_003730 COc1cc(ccc1OCC(=O)N)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J13 compound treatment 284.7 91.0 0.47 285.6 98.5 0.51 0.6977 0.9993 1419738 ChemDiv1_003731 COc1ccc(cc1COc2ccc(NC(=O)C)cc2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J14 compound treatment 283.7 90.0 0.47 281.3 94.2 0.49 0.6783 0.9998 1972125 ChemDiv1_003732 COc1ccc(/C=C/2\CN(C)CC3=C2OC(=C(C#N)C3c4ccc(OC)c(OC)c4)N)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J15 compound treatment 279.2 85.5 0.45 282.8 95.7 0.5 0.6672 0.9985 1189649 ChemDiv1_003733 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J16 compound treatment 285.9 92.2 0.48 288.0 101.0 0.52 0.711 0.9991 1296335 ChemDiv1_003734 COc1ccc(cc1COc2cccc(Cl)c2)C3C(=C(N)Oc4n[nH]c(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J17 compound treatment 286.9 93.2 0.49 283.0 95.9 0.5 0.6963 0.9999 1972126 ChemDiv1_003735 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J18 compound treatment 278.0 84.3 0.44 282.6 95.5 0.5 0.662 0.9982 1257070 ChemDiv1_003736 CCN(CC)C(=O)COc1ccc(cc1OC)C2C(=C(N)Oc3n[nH]c(COC)c23)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J19 compound treatment 283.6 89.9 0.47 282.4 95.3 0.5 0.6819 0.9996 1932003 ChemDiv1_003737 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc([N+](=O)[O-])c(C)c4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J20 compound treatment 277.5 83.8 0.44 281.7 94.6 0.49 0.6569 0.9983 1972127 ChemDiv1_003738 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2cccc(OCc3ccccc3)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J21 compound treatment 281.0 87.3 0.46 278.3 91.2 0.47 0.6573 0.9998 1454491 ChemDiv1_003739 Cn1c(nc2ccccc12)n3c(CN4C(=O)c5ccccc5C4=O)nc6ccccc6c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J22 compound treatment 281.0 87.3 0.46 284.2 97.1 0.5 0.679 0.9987 1329005 ChemDiv1_003740 CS(=O)(=O)Cc1nc2ccccc2[nH]c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J23 mock treatment 281.8 88.1 0.46 278.6 91.5 0.48 0.6613 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 J24 mock treatment 79.6 -114.0 -0.6 76.2 -111.0 -0.58 -0.8285 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K01 compound treatment 284.9 91.2 0.48 288.3 101.0 0.53 0.7084 0.9988 1972128 ChemDiv1_003741 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K02 compound treatment 285.5 91.8 0.48 285.6 98.5 0.51 0.7007 0.9994 1513122 ChemDiv1_003742 CC1CCc2c(C(=O)N)c(NC(=O)CCN3C(=O)c4ccccc4C3=O)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K03 compound treatment 284.9 91.2 0.48 285.6 98.5 0.51 0.6985 0.9993 1972129 ChemDiv1_003743 COc1ccc(cc1)c2cc(C(=O)Nc3cccc(c3)C(=O)C)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K04 compound treatment 285.3 91.6 0.48 283.4 96.3 0.5 0.6919 0.9997 1551904 ChemDiv1_003744 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K05 compound treatment 284.1 90.4 0.47 287.0 99.9 0.52 0.7007 0.9989 1479033 ChemDiv1_003745 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc5OCOc5c4)C(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K06 compound treatment 278.9 85.2 0.44 286.5 99.4 0.52 0.6797 0.9972 1972130 ChemDiv1_003746 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K07 compound treatment 285.0 91.3 0.48 285.8 98.7 0.51 0.6996 0.9993 1213027 ChemDiv1_003747 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccs4)C(=O)Cc5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K08 compound treatment 284.0 90.3 0.47 281.6 94.5 0.49 0.6805 0.9998 1389135 ChemDiv1_003748 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(F)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K09 compound treatment 288.4 94.7 0.49 281.8 94.7 0.49 0.6974 1.0 1972131 ChemDiv1_003749 CN(C)/C=C\1/C(=O)N(N=C1c2ccccc2)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K10 compound treatment 281.1 87.4 0.46 282.4 95.3 0.5 0.6727 0.9992 1552821 ChemDiv1_003750 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K11 compound treatment 286.7 93.0 0.49 286.7 99.6 0.52 0.7092 0.9995 1972132 ChemDiv1_003751 CCCCCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cccc(OC)c4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K12 compound treatment 278.7 85.0 0.44 276.4 89.3 0.46 0.6418 0.9997 1496326 ChemDiv1_003752 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K13 compound treatment 278.4 84.7 0.44 281.8 94.7 0.49 0.6605 0.9986 1972133 ChemDiv1_003753 CCCCCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K14 compound treatment 279.9 86.2 0.45 282.6 95.5 0.5 0.669 0.9988 1972134 ChemDiv1_003754 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K15 compound treatment 282.1 88.4 0.46 281.4 94.3 0.49 0.6727 0.9995 1373102 ChemDiv1_003755 COc1ccc(cc1COc2ccc(F)cc2)C3N(C(=O)C)c4ccccc4NC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K16 compound treatment 279.2 85.5 0.45 284.5 97.4 0.51 0.6734 0.998 1352004 ChemDiv1_003756 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K17 compound treatment 283.1 89.4 0.47 281.7 94.6 0.49 0.6775 0.9997 1719199 ChemDiv1_003757 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)c(OC)c5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K18 compound treatment 280.9 87.2 0.46 282.3 95.2 0.49 0.6716 0.9991 1412842 ChemDiv1_003758 COc1cc(cc(OC)c1OC)c2cc(nc3sc(C(=O)O)c(N)c23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K19 compound treatment 282.5 88.8 0.46 282.5 95.4 0.5 0.6782 0.9994 1947628 ChemDiv1_003759 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K20 compound treatment 281.4 87.7 0.46 279.2 92.1 0.48 0.6621 0.9997 1972135 ChemDiv1_003760 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c(C)c(C)c3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K21 compound treatment 280.3 86.6 0.45 277.0 89.9 0.47 0.6499 0.9999 1947607 ChemDiv1_003761 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K22 compound treatment 282.4 88.7 0.46 277.0 89.9 0.47 0.6577 1.0 1559240 ChemDiv1_003762 CC1(C)Cc2c(CS1)c(nc3sc(C(=O)c4ccccc4)c(N)c23)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K23 mock treatment 281.9 88.2 0.46 285.0 97.9 0.51 0.6852 0.9987 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 K24 mock treatment 83.4 -110.0 -0.58 77.2 -110.0 -0.57 -0.8108 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L01 compound treatment 284.6 90.9 0.47 284.7 97.6 0.51 0.6941 0.9994 1972136 ChemDiv1_003763 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L02 compound treatment 285.7 92.0 0.48 280.7 93.6 0.49 0.6834 1.0 1169379 ChemDiv1_003764 CCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L03 compound treatment 283.3 89.6 0.47 283.0 95.9 0.5 0.683 0.9995 1166341 ChemDiv1_003765 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(OC)c(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L04 compound treatment 281.4 87.7 0.46 282.5 95.4 0.5 0.6742 0.9992 1470873 ChemDiv1_003766 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2OC(=O)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L05 compound treatment 278.0 84.3 0.44 287.3 100.0 0.52 0.6793 0.9965 1278030 ChemDiv1_003767 COc1ccc(cc1OC)C2N(C(=O)C(C)C)c3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L06 compound treatment 284.5 90.8 0.47 284.0 96.9 0.5 0.6911 0.9995 1512237 ChemDiv1_003768 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L07 compound treatment 283.5 89.8 0.47 287.6 100.0 0.52 0.7007 0.9985 1657300 ChemDiv1_003769 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3o2)scc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L08 compound treatment 285.4 91.7 0.48 281.8 94.7 0.49 0.6864 0.9999 1972137 ChemDiv1_003770 COC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L09 compound treatment 285.9 92.2 0.48 282.1 95.0 0.49 0.6893 0.9999 1326813 ChemDiv1_003771 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(CSc5nc6ccccc6s5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L10 compound treatment 279.7 86.0 0.45 283.0 95.9 0.5 0.6697 0.9986 1972138 ChemDiv1_003772 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L11 compound treatment 283.4 89.7 0.47 286.9 99.8 0.52 0.6977 0.9987 1972139 ChemDiv1_003773 COc1ccc(cc1Cn2nc(C)c([N+](=O)[O-])c2C)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L12 compound treatment 287.0 93.3 0.49 284.1 97.0 0.5 0.7007 0.9998 1972140 ChemDiv1_003774 NC1=C(C#N)C(c2ccc(F)cc2Br)c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L13 compound treatment 283.0 89.3 0.47 281.2 94.1 0.49 0.6753 0.9997 1637737 ChemDiv1_003775 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L14 compound treatment 292.6 98.9 0.52 290.9 104.0 0.54 0.7464 0.9998 1224452 ChemDiv1_003776 CC1=C(C(C(=C(S)N1)C#N)c2ccsc2)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L15 compound treatment 284.8 91.1 0.48 284.7 97.6 0.51 0.6948 0.9995 1972141 ChemDiv1_003777 COc1ccc(cc1COc2ccc([N+](=O)[O-])c(C)c2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L16 compound treatment 277.2 83.5 0.44 281.0 93.9 0.49 0.6532 0.9984 1972142 ChemDiv1_003778 COc1ccc(cc1Cn2nc([N+](=O)[O-])c(Br)c2C)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L17 compound treatment 280.6 86.9 0.45 284.5 97.4 0.51 0.6786 0.9985 1972143 ChemDiv1_003779 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4c6cccc7ccccc67 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L18 compound treatment 285.7 92.0 0.48 281.5 94.4 0.49 0.6864 0.9999 1633285 ChemDiv1_003780 CCN(CC)C(=O)COc1ccc(cc1OC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L19 compound treatment 278.8 85.1 0.44 279.8 92.7 0.48 0.6547 0.9992 1972144 ChemDiv1_003781 CCN(CC)C(=O)CN1C(=O)C2CCC(=O)CC2C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L20 compound treatment 281.8 88.1 0.46 282.0 94.9 0.49 0.6738 0.9994 1972145 ChemDiv1_003782 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L21 compound treatment 278.8 85.1 0.44 280.0 92.9 0.48 0.6554 0.9991 1402136 ChemDiv1_003783 COc1ccccc1n2c(CCN3C(=O)c4ccccc4C3=O)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L22 compound treatment 285.1 91.4 0.48 282.8 95.7 0.5 0.6889 0.9998 1315025 ChemDiv1_003784 Oc1ccc(cc1)C2Nc3ccc4ccccc4c3C5C=CCC52 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L23 mock treatment 280.4 86.7 0.45 280.0 92.9 0.48 0.6613 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 L24 mock treatment 88.6 -105.0 -0.55 81.5 -106.0 -0.55 -0.7758 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M01 compound treatment 285.1 91.4 0.48 287.0 99.9 0.52 0.7044 0.9991 1949666 ChemDiv1_003785 CCOc1cc([N+](=O)[O-])c2NC(C3CC=CC3c2c1)c4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M02 compound treatment 282.8 89.1 0.46 277.6 90.5 0.47 0.6613 1.0 1972146 ChemDiv1_003786 CCC(C)OC(=O)CSc1nc2ccccc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M03 compound treatment 287.0 93.3 0.49 282.4 95.3 0.5 0.6945 1.0 1251151 ChemDiv1_003787 COc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M04 compound treatment 282.9 89.2 0.47 285.5 98.4 0.51 0.6907 0.9989 1947665 ChemDiv1_003788 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M05 compound treatment 279.9 86.2 0.45 283.1 96.0 0.5 0.6709 0.9987 1152342 ChemDiv1_003789 Clc1ccc2[nH]c(=O)c(Sc3nc4ccccc4o3)c(c5ccccc5)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M06 compound treatment 283.5 89.8 0.47 283.4 96.3 0.5 0.6852 0.9995 1972147 ChemDiv1_003790 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M07 compound treatment 286.4 92.7 0.48 286.1 99.0 0.51 0.7059 0.9995 1621548 ChemDiv1_003791 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M08 compound treatment 281.5 87.8 0.46 280.3 93.2 0.48 0.6665 0.9996 1440054 ChemDiv1_003792 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cc4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M09 compound treatment 279.3 85.6 0.45 283.5 96.4 0.5 0.6701 0.9984 1942532 ChemDiv1_003793 CN(C)/C=C/1\C(=O)N(N=C1c2ccccc2)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M10 compound treatment 282.8 89.1 0.46 280.6 93.5 0.49 0.6724 0.9998 1972148 ChemDiv1_003794 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc([N+](=O)[O-])c(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M11 compound treatment 283.2 89.5 0.47 283.9 96.8 0.5 0.686 0.9993 1972149 ChemDiv1_003795 COc1cccc(C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M12 compound treatment 282.3 88.6 0.46 281.2 94.1 0.49 0.6727 0.9996 1972150 ChemDiv1_003796 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M13 compound treatment 279.4 85.7 0.45 285.0 97.9 0.51 0.676 0.9979 1972151 ChemDiv1_003797 COc1ccc(OC)c(c1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M14 compound treatment 282.0 88.3 0.46 282.6 95.5 0.5 0.6768 0.9993 1305534 ChemDiv1_003798 CCOc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M15 compound treatment 280.0 86.3 0.45 279.0 91.9 0.48 0.6562 0.9996 1972152 ChemDiv1_003799 CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5ccc(cc5C)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M16 compound treatment 279.9 86.2 0.45 282.0 94.9 0.49 0.6668 0.9989 1214079 ChemDiv1_003800 OCCNc1nc(c2ccccc2)c3cc(Br)ccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M17 compound treatment 279.4 85.7 0.45 281.2 94.1 0.49 0.662 0.999 1972153 ChemDiv1_003801 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)c(OC)c5)C(=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M18 compound treatment 282.0 88.3 0.46 276.5 89.4 0.46 0.6543 1.0 1972154 ChemDiv1_003802 COc1cc(cc(OC)c1OC)c2cc(nc(SCC(=O)O)c2C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M19 compound treatment 279.0 85.3 0.45 279.7 92.6 0.48 0.655 0.9992 1947347 ChemDiv1_003803 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC)c(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M20 compound treatment 280.6 86.9 0.45 281.0 93.9 0.49 0.6657 0.9993 1972155 ChemDiv1_003804 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(C)cc(c3C#N)C(F)(F)F)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M21 compound treatment 279.7 86.0 0.45 280.9 93.8 0.49 0.662 0.9991 1244208 ChemDiv1_003805 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC(=O)C)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M22 compound treatment 284.3 90.6 0.47 281.1 94.0 0.49 0.6797 0.9999 1972156 ChemDiv1_003806 CC1(C)Cc2c(CO1)sc3nc(SCC(=O)O)n(c4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M23 mock treatment 280.8 87.1 0.45 278.9 91.8 0.48 0.6587 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 M24 mock treatment 206.5 12.8 0.07 188.8 1.68 0.01 0.0535 0.7927 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N01 compound treatment 284.2 90.5 0.47 286.7 99.6 0.52 0.6999 0.999 1972157 ChemDiv1_003807 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N02 compound treatment 277.3 83.6 0.44 275.4 88.3 0.46 0.633 0.9997 1565660 ChemDiv1_003808 Cc1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N03 compound treatment 282.8 89.1 0.46 284.2 97.1 0.5 0.6856 0.9992 1471743 ChemDiv1_003809 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(C)c(C)cc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N04 compound treatment 282.7 89.0 0.46 283.7 96.6 0.5 0.6834 0.9992 1442690 ChemDiv1_003810 COc1ccc(cc1Br)C(=O)On2c(nc3ccccc3c2=O)c4ccc(cc4)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N05 compound treatment 282.6 88.9 0.46 282.6 95.5 0.5 0.679 0.9994 1950708 ChemDiv1_003811 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N06 compound treatment 281.1 87.4 0.46 285.0 97.9 0.51 0.6823 0.9985 1972158 ChemDiv1_003812 Fc1ccc(N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4sc5ccccc5c4Cl)c(F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N07 compound treatment 284.9 91.2 0.48 283.9 96.8 0.5 0.6922 0.9996 1308177 ChemDiv1_003813 CCOC(=O)c1cnn(c1NC(=O)CSc2nc3ccc(OCC)cc3s2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N08 compound treatment 282.3 88.6 0.46 281.2 94.1 0.49 0.6727 0.9996 1972159 ChemDiv1_003814 COC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N09 compound treatment 282.6 88.9 0.46 284.2 97.1 0.5 0.6849 0.9991 1206117 ChemDiv1_003815 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(COc5ccc(NC(=O)C)cc5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N10 compound treatment 284.3 90.6 0.47 281.3 94.2 0.49 0.6805 0.9998 1716002 ChemDiv1_003816 NC1=C(C#N)C(c2cccc(Br)c2)c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N11 compound treatment 280.0 86.3 0.45 282.0 94.9 0.49 0.6672 0.999 1670964 ChemDiv1_003817 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N12 compound treatment 279.0 85.3 0.45 281.6 94.5 0.49 0.662 0.9988 1161866 ChemDiv1_003818 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OCc4ccccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N13 compound treatment 284.4 90.7 0.47 281.2 94.1 0.49 0.6805 0.9999 1202218 ChemDiv1_003819 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N14 compound treatment 285.2 91.5 0.48 283.8 96.7 0.5 0.693 0.9997 1367931 ChemDiv1_003820 Cc1cc2OC(=C(C#N)C(c3ccccc3OCc4ccccc4Cl)c2c(=O)o1)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N15 compound treatment 282.3 88.6 0.46 284.2 97.1 0.5 0.6838 0.999 1342184 ChemDiv1_003821 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4Cc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N16 compound treatment 286.3 92.6 0.48 280.7 93.6 0.49 0.6856 1.0 1972160 ChemDiv1_003822 COc1ccc(cc1COc2ccccc2C)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N17 compound treatment 282.6 88.9 0.46 280.9 93.8 0.49 0.6727 0.9997 1972161 ChemDiv1_003823 CCOC(=O)c1ccccc1OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N18 compound treatment 282.0 88.3 0.46 279.6 92.5 0.48 0.6657 0.9998 1972162 ChemDiv1_003824 COc1ccc(Br)cc1C2C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N19 compound treatment 278.6 84.9 0.44 274.9 87.8 0.46 0.6359 0.9999 1972163 ChemDiv1_003825 O=C1C2CCC3(CC2C(=O)N1Cc4ccccc4)OCCO3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N20 compound treatment 283.9 90.2 0.47 283.4 96.3 0.5 0.6867 0.9995 1282289 ChemDiv1_003826 CCCOc1ccc(cc1OC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N21 compound treatment 281.3 87.6 0.46 277.9 90.8 0.47 0.6569 0.9999 1724806 ChemDiv1_003827 O=C1N(CCCc2nc3ccccc3c(=O)n2Cc4ccccc4)C(=O)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N22 compound treatment 279.7 86.0 0.45 274.6 87.5 0.45 0.6389 1.0 1463713 ChemDiv1_003828 Clc1ccc(C2Nc3c(cccc3C4C=CCC42)C(=O)N5CCCC5)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N23 mock treatment 282.4 88.7 0.46 278.4 91.3 0.47 0.6628 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 N24 mock treatment 201.4 7.73 0.04 188.9 1.78 0.01 0.0351 0.8474 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O01 compound treatment 285.3 91.6 0.48 284.8 97.7 0.51 0.697 0.9995 1972164 ChemDiv1_003829 CC(=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O02 compound treatment 284.0 90.3 0.47 286.4 99.3 0.52 0.6981 0.999 1972165 ChemDiv1_003830 CC(C)(C)c1ccc(Oc2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O03 compound treatment 286.5 92.8 0.48 284.8 97.7 0.51 0.7014 0.9997 1222174 ChemDiv1_003831 CCOC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O04 compound treatment 285.1 91.4 0.48 281.2 94.1 0.49 0.6831 0.9999 1947746 ChemDiv1_003832 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O05 compound treatment 282.8 89.1 0.46 285.0 97.9 0.51 0.6885 0.999 1156086 ChemDiv1_003833 CCCCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O06 compound treatment 278.8 85.1 0.44 279.8 92.7 0.48 0.6547 0.9992 1267091 ChemDiv1_003834 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OC(C)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O07 compound treatment 284.1 90.4 0.47 284.1 97.0 0.5 0.69 0.9994 1972166 ChemDiv1_003835 CC(C)C(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(Br)s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O08 compound treatment 281.0 87.3 0.46 279.5 92.4 0.48 0.6617 0.9997 1972167 ChemDiv1_003836 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O09 compound treatment 281.4 87.7 0.46 280.6 93.5 0.49 0.6672 0.9996 1623516 ChemDiv1_003837 COc1ccc(cc1OC)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O10 compound treatment 282.0 88.3 0.46 283.8 96.7 0.5 0.6812 0.9991 1972168 ChemDiv1_003838 COc1cc(OC)cc(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O11 compound treatment 281.8 88.1 0.46 281.7 94.6 0.49 0.6727 0.9994 1440060 ChemDiv1_003839 CCOc1cc(ccc1OC(=O)C)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O12 compound treatment 281.6 87.9 0.46 282.3 95.2 0.49 0.6742 0.9993 1425465 ChemDiv1_003840 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cccnc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O13 compound treatment 282.8 89.1 0.46 283.2 96.1 0.5 0.6819 0.9994 1783841 ChemDiv1_003841 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3NC2c4ccc(o4)c5ccc(cc5Cl)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O14 compound treatment 280.4 86.7 0.45 281.2 94.1 0.49 0.6657 0.9992 1672961 ChemDiv1_003842 CCOc1cc(ccc1OC(=O)C)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O15 compound treatment 283.5 89.8 0.47 281.8 94.7 0.49 0.6794 0.9997 1512562 ChemDiv1_003843 CCOc1ccccc1C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O16 compound treatment 279.8 86.1 0.45 278.0 90.9 0.47 0.6517 0.9997 1927506 ChemDiv1_003844 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O17 compound treatment 284.2 90.5 0.47 282.3 95.2 0.49 0.6838 0.9997 1373677 ChemDiv1_003845 COc1cc(cc(OC)c1OC)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O18 compound treatment 282.0 88.3 0.46 276.6 89.5 0.47 0.6547 1.0 1972169 ChemDiv1_003846 Cc1nc(SCC(=O)c2ccc(Br)cc2)c(C#N)c(C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O19 compound treatment 284.4 90.7 0.47 278.7 91.6 0.48 0.6713 1.0 1948568 ChemDiv1_003847 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O20 compound treatment 280.1 86.4 0.45 277.1 90.0 0.47 0.6495 0.9998 1500574 ChemDiv1_003848 Cc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O21 compound treatment 281.3 87.6 0.46 277.3 90.2 0.47 0.6547 0.9999 1972170 ChemDiv1_003849 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3ccc(c4nc5ccccc5s4)c(O)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O22 compound treatment 281.1 87.4 0.46 277.9 90.8 0.47 0.6562 0.9999 1697087 ChemDiv1_003850 O=c1n(c2ccccc2)c(=S)[nH]c3sc4CCCc4c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O23 mock treatment 282.6 88.9 0.46 277.4 90.3 0.47 0.6599 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 O24 mock treatment 177.7 -16.0 -0.08 88.6 -98.5 -0.51 -0.421 -0.8115 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P01 compound treatment 282.9 89.2 0.47 286.1 99.0 0.51 0.6929 0.9987 1972171 ChemDiv1_003851 COc1ccc(/C=C(\C#N)/C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P02 compound treatment 286.2 92.5 0.48 282.2 95.1 0.49 0.6908 0.9999 1707355 ChemDiv1_003852 CCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(cc4)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P03 compound treatment 282.6 88.9 0.46 288.4 101.0 0.53 0.7003 0.998 1467969 ChemDiv1_003853 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P04 compound treatment 280.1 86.4 0.45 284.2 97.1 0.5 0.6756 0.9984 1206674 ChemDiv1_003854 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4cc(Cl)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P05 compound treatment 281.7 88.0 0.46 281.8 94.7 0.49 0.6727 0.9994 1118146 ChemDiv1_003855 COc1cc(cc(OC)c1OC)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P06 compound treatment 281.3 87.6 0.46 278.8 91.7 0.48 0.6602 0.9998 1924167 ChemDiv1_003856 COc1ccccc1c2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P07 compound treatment 284.2 90.5 0.47 281.6 94.5 0.49 0.6812 0.9998 1517667 ChemDiv1_003857 COc1ccc(cc1COc2ccc(F)cc2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P08 compound treatment 281.0 87.3 0.46 284.2 97.1 0.5 0.679 0.9987 1972172 ChemDiv1_003858 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2ccccc2F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P09 compound treatment 277.9 84.2 0.44 282.0 94.9 0.49 0.6594 0.9983 1473601 ChemDiv1_003859 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(CSc5ccccn5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P10 compound treatment 281.8 88.1 0.46 282.0 94.9 0.49 0.6738 0.9994 1972173 ChemDiv1_003860 CCCCOc1ccc(cc1OC)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P11 compound treatment 281.3 87.6 0.46 287.3 100.0 0.52 0.6915 0.9979 1612531 ChemDiv1_003861 COc1ccc(cc1COc2ccc(NC(=O)C)cc2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P12 compound treatment 281.6 87.9 0.46 281.2 94.1 0.49 0.6701 0.9995 1505633 ChemDiv1_003862 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OCc4ccc(Cl)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P13 compound treatment 286.4 92.7 0.48 286.0 98.9 0.51 0.7055 0.9995 1424987 ChemDiv1_003863 COc1ccc(cc1COc2ccccc2F)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P14 compound treatment 275.5 81.8 0.43 284.5 97.4 0.51 0.6598 0.9964 1972174 ChemDiv1_003864 COc1ccc(cc1COc2ccc(F)cc2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P15 compound treatment 286.1 92.4 0.48 283.6 96.5 0.5 0.6956 0.9998 1434459 ChemDiv1_003865 COc1ccc(cc1CSc2nc3ccccc3s2)C4Nc5ccccc5C(=O)N4Cc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P16 compound treatment 285.8 92.1 0.48 283.9 96.8 0.5 0.6956 0.9997 1972175 ChemDiv1_003866 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(o3)c4cc(ccc4Cl)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P17 compound treatment 280.1 86.4 0.45 282.3 95.2 0.49 0.6687 0.9989 1348575 ChemDiv1_003867 COc1cccc(OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P18 compound treatment 282.2 88.5 0.46 279.2 92.1 0.48 0.665 0.9998 1972176 ChemDiv1_003868 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(cc2)C(F)(F)F)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P19 compound treatment 282.4 88.7 0.46 281.3 94.2 0.49 0.6735 0.9996 1366774 ChemDiv1_003869 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P20 compound treatment 277.8 84.1 0.44 280.6 93.5 0.49 0.6539 0.9987 1398782 ChemDiv1_003870 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OCc4ccccc4)cc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P21 compound treatment 281.6 87.9 0.46 280.6 93.5 0.49 0.6679 0.9996 1263674 ChemDiv1_003871 O=C1N(CCCc2nc3ccccc3c(=O)n2CCCn4ccnc4)C(=O)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P22 compound treatment 279.4 85.7 0.45 279.9 92.8 0.48 0.6572 0.9993 1784338 ChemDiv1_003872 [O-][N+](=O)c1cccc(c1)C2Nc3c(cccc3C4C=CCC42)C(=O)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P23 mock treatment 287.4 93.7 0.49 279.4 92.3 0.48 0.6849 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.597 P24 mock treatment 113.2 -80.5 -0.42 98.5 -88.6 -0.46 -0.6226 -0.9989 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A01 compound treatment 285.0 94.9 0.49 284.6 97.5 0.51 0.7082 0.9999 1463327 ChemDiv1_003873 CC(NC(=O)c1ccc2OCCOc2c1)C3(CC4CC5CC(C4)C3)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A02 compound treatment 286.2 96.1 0.5 282.8 95.7 0.5 0.706 1.0 1723746 ChemDiv1_003874 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OCc5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A03 compound treatment 280.9 90.8 0.47 281.4 94.3 0.49 0.6813 0.9999 1563473 ChemDiv1_003875 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A04 compound treatment 281.3 91.2 0.48 282.9 95.8 0.5 0.6883 0.9997 1949072 ChemDiv1_003876 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(F)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A05 compound treatment 282.8 92.7 0.48 281.2 94.1 0.49 0.6876 1.0 1972177 ChemDiv1_003877 Cc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A06 compound treatment 283.8 93.7 0.49 280.6 93.5 0.49 0.6891 1.0 1972178 ChemDiv1_003878 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A07 compound treatment 279.4 89.3 0.47 281.1 94.0 0.49 0.6747 0.9997 1972179 ChemDiv1_003879 CC(C)(C)c1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A08 compound treatment 281.2 91.1 0.48 286.2 99.1 0.51 0.7001 0.9992 1924438 ChemDiv1_003880 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A09 compound treatment 282.6 92.5 0.48 286.9 99.8 0.52 0.7078 0.9993 1972180 ChemDiv1_003881 Brc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A10 compound treatment 307.7 118.0 0.61 318.6 131.0 0.68 0.9169 0.9985 1729280 ChemDiv1_003882 CC(=O)Nc1ccc(cc1)c2nc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A11 compound treatment 280.8 90.7 0.47 280.1 93.0 0.48 0.6762 0.9999 1438346 ChemDiv1_003883 CCOc1cc(ccc1OC(=O)C2CC2)C3Nc4ccccc4NC5=C3C(=O)CC(C5)c6ccc(OC)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A12 compound treatment 288.5 98.4 0.51 288.9 102.0 0.53 0.7369 0.9999 1331516 ChemDiv1_003884 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5ccc(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A13 compound treatment 278.6 88.5 0.46 281.0 93.9 0.49 0.6714 0.9996 1339658 ChemDiv1_003885 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(Br)s5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A14 compound treatment 290.3 100.0 0.52 292.1 105.0 0.55 0.7553 0.9998 1972181 ChemDiv1_003886 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3Br)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A15 compound treatment 280.9 90.8 0.47 281.5 94.4 0.49 0.6817 0.9998 1924588 ChemDiv1_003887 Brc1cc2OCOc2cc1C3Nc4ccccc4NC5=C3C(=O)CC(C5)c6ccc7OCOc7c6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A16 compound treatment 280.0 89.9 0.47 280.3 93.2 0.48 0.674 0.9999 1471125 ChemDiv1_003888 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3ccccc3C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A17 compound treatment 280.6 90.5 0.47 283.3 96.2 0.5 0.6872 0.9996 1929185 ChemDiv1_003889 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc(Cl)c1OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A18 compound treatment 280.4 90.3 0.47 275.3 88.2 0.46 0.6571 0.9999 1163079 ChemDiv1_003890 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccccc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A19 compound treatment 273.4 83.3 0.43 277.8 90.7 0.47 0.6404 0.9992 1972182 ChemDiv1_003891 CCOC(=O)COc1ccc(Br)cc1C=C2C(=O)NC(=O)NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A20 compound treatment 277.5 87.4 0.46 274.6 87.5 0.45 0.6438 1.0 1972183 ChemDiv1_003892 COc1ccc(Br)c(c1)C(=O)On2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A21 compound treatment 283.1 93.0 0.48 283.4 96.3 0.5 0.6968 0.9999 1972184 ChemDiv1_003893 COc1cc(ccc1OCC(=O)Nc2ccc3OCOc3c2)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A22 compound treatment 281.6 91.5 0.48 275.5 88.4 0.46 0.6622 0.9998 1972185 ChemDiv1_003894 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Br)ccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A23 mock treatment 284.2 94.1 0.49 281.1 94.0 0.49 0.6924 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 A24 mock treatment 91.3 -98.8 -0.52 79.2 -108.0 -0.56 -0.7612 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B01 compound treatment 281.0 90.9 0.47 282.6 95.5 0.5 0.6861 0.9997 1972186 ChemDiv1_003895 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B02 compound treatment 287.2 97.1 0.51 283.4 96.3 0.5 0.7119 1.0 1925285 ChemDiv1_003896 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)c6cccs6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B03 compound treatment 282.0 91.9 0.48 282.3 95.2 0.49 0.6887 0.9999 1929108 ChemDiv1_003897 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B04 compound treatment 283.5 93.4 0.49 282.9 95.8 0.5 0.6964 0.9999 1972187 ChemDiv1_003898 COc1cc(cc(OC)c1OC)C2CC(n3ncc(C(=O)N4CCN(CC4)C(c5ccccc5)c6ccccc6)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B05 compound treatment 285.0 94.9 0.49 280.0 92.9 0.48 0.6913 0.9999 1929184 ChemDiv1_003899 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OS(=O)(=O)c3ccc(C)cc3)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B06 compound treatment 285.7 95.6 0.5 285.0 97.9 0.51 0.7123 0.9999 1972188 ChemDiv1_003900 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)Nc3sc4CCCCc4c3C#N)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B07 compound treatment 313.4 123.0 0.64 329.0 142.0 0.74 0.9762 0.9977 1948721 ChemDiv1_003901 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B08 compound treatment 287.3 97.2 0.51 284.2 97.1 0.5 0.7152 1.0 1925250 ChemDiv1_003902 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B09 compound treatment 282.6 92.5 0.48 283.3 96.2 0.5 0.6946 0.9998 1379236 ChemDiv1_003903 CC1CCCN(CN2C(=O)C3(OCCO3)c4ccccc24)C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B10 compound treatment 277.0 86.9 0.45 281.2 94.1 0.49 0.6662 0.9993 1972189 ChemDiv1_003904 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B11 compound treatment 277.2 87.1 0.45 285.9 98.8 0.51 0.6842 0.9981 1972190 ChemDiv1_003905 Fc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B12 compound treatment 282.2 92.1 0.48 279.9 92.8 0.48 0.6806 1.0 1972191 ChemDiv1_003906 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B13 compound treatment 277.6 87.5 0.46 278.5 91.4 0.47 0.6585 0.9998 1972192 ChemDiv1_003907 CC1CCc2c(C(=O)N)c(NC(=O)c3cc4nc(cc(n4n3)C(F)(F)F)c5ccco5)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B14 compound treatment 282.2 92.1 0.48 279.7 92.6 0.48 0.6799 1.0 1972193 ChemDiv1_003908 Cc1ccc(cc1)C2CC(n3nc(C(=O)N4CCN(CC4)C(=O)c5ccccc5)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B15 compound treatment 276.9 86.8 0.45 281.8 94.7 0.49 0.668 0.9991 1972194 ChemDiv1_003909 Cc1ccc(cc1)c2cc(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B16 compound treatment 277.2 87.1 0.45 279.7 92.6 0.48 0.6614 0.9996 1930326 ChemDiv1_003910 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCc4cccs4)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B17 compound treatment 280.5 90.4 0.47 282.2 95.1 0.49 0.6828 0.9997 1972195 ChemDiv1_003911 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3ccc(Cl)cc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B18 compound treatment 279.4 89.3 0.47 278.2 91.1 0.47 0.664 1.0 1972196 ChemDiv1_003912 Cc1ccc(cc1)C2CC(n3ncc(C(=O)Nc4cc(Sc5ccc(Br)cc5)cc(c4)[N+](=O)[O-])c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B19 compound treatment 279.5 89.4 0.47 280.2 93.1 0.48 0.6718 0.9998 1924548 ChemDiv1_003913 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)c(OC)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B20 compound treatment 275.7 85.6 0.45 277.5 90.4 0.47 0.6478 0.9997 1972197 ChemDiv1_003914 O=C(N1CCOCC1)c2ccc(NS(=O)(=O)c3ccc4C(=O)c5ccccc5C(=O)c4c3)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B21 compound treatment 278.7 88.6 0.46 278.1 91.0 0.47 0.6611 0.9999 1930258 ChemDiv1_003915 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B22 compound treatment 294.0 104.0 0.54 291.8 105.0 0.54 0.7679 1.0 1446667 ChemDiv1_003916 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B23 mock treatment 279.5 89.4 0.47 280.0 92.9 0.48 0.671 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 B24 mock treatment 76.1 -114.0 -0.59 80.2 -107.0 -0.56 -0.8136 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C01 compound treatment 283.4 93.3 0.49 284.0 96.9 0.5 0.7001 0.9999 1175574 ChemDiv1_003917 CCOc1cccc(c1)C(=O)Nc2cc(ccc2Cl)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C02 compound treatment 319.8 130.0 0.68 299.4 112.0 0.58 0.891 0.9973 1611526 ChemDiv1_003918 COc1cc(C=c2sc3nc4ccccc4n3c2=O)c(Br)cc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C03 compound treatment 282.5 92.4 0.48 280.7 93.6 0.49 0.6847 1.0 1222832 ChemDiv1_003919 O=C(CSc1nc2ccccc2s1)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C04 compound treatment 284.9 94.8 0.49 283.3 96.2 0.5 0.7031 1.0 1924433 ChemDiv1_003920 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C05 compound treatment 281.6 91.5 0.48 286.9 99.8 0.52 0.7041 0.9991 1972198 ChemDiv1_003921 CCCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C06 compound treatment 284.4 94.3 0.49 286.0 98.9 0.51 0.7111 0.9998 1972199 ChemDiv1_003922 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C07 compound treatment 281.5 91.4 0.48 285.0 97.9 0.51 0.6968 0.9995 1972200 ChemDiv1_003923 Clc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C08 compound treatment 281.5 91.4 0.48 284.5 97.4 0.51 0.6949 0.9995 1924587 ChemDiv1_003924 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C09 compound treatment 285.4 95.3 0.5 284.9 97.8 0.51 0.7108 0.9999 1972201 ChemDiv1_003925 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(C)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C10 compound treatment 278.6 88.5 0.46 280.0 92.9 0.48 0.6677 0.9997 1156448 ChemDiv1_003926 CC(=O)Nc1ccc(cc1)c2nc(c3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C11 compound treatment 277.7 87.6 0.46 280.1 93.0 0.48 0.6647 0.9996 1284246 ChemDiv1_003927 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(O)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C12 compound treatment 280.9 90.8 0.47 283.0 95.9 0.5 0.6872 0.9997 1972202 ChemDiv1_003928 COc1cc(/C=C/2\Sc3ccccc3C2=O)cc(Cl)c1OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C13 compound treatment 282.1 92.0 0.48 284.1 97.0 0.5 0.6957 0.9997 1674807 ChemDiv1_003929 CCOc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C14 compound treatment 274.6 84.5 0.44 279.3 92.2 0.48 0.6504 0.9991 1972203 ChemDiv1_003930 COc1cc(Br)c(cc1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C15 compound treatment 282.9 92.8 0.48 281.4 94.3 0.49 0.6887 1.0 1972204 ChemDiv1_003931 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(cc5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C16 compound treatment 281.7 91.6 0.48 280.2 93.1 0.48 0.6799 1.0 1145640 ChemDiv1_003932 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3ccc(OC)cc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C17 compound treatment 279.7 89.6 0.47 278.5 91.4 0.47 0.6662 1.0 1947191 ChemDiv1_003933 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(Cl)c(c3)C(=O)O)c4cccc(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C18 compound treatment 286.3 96.2 0.5 284.2 97.1 0.5 0.7115 1.0 1948720 ChemDiv1_003934 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc6OCOc6cc5[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C19 compound treatment 376.8 187.0 0.97 385.7 199.0 1.03 1.4184 0.9996 1972205 ChemDiv1_003935 COc1cc(/C=C/2\Sc3ccccc3C2=O)cc(Br)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C20 compound treatment 280.0 89.9 0.47 279.7 92.6 0.48 0.6718 0.9999 1972206 ChemDiv1_003936 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(c(Br)c4C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C21 compound treatment 282.0 91.9 0.48 275.2 88.1 0.46 0.6626 0.9997 1229431 ChemDiv1_003937 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C22 compound treatment 279.6 89.5 0.47 272.4 85.3 0.44 0.6435 0.9997 1972207 ChemDiv1_003938 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(c(Br)c4C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C23 mock treatment 284.1 94.0 0.49 276.1 89.0 0.46 0.6737 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 C24 mock treatment 90.0 -100.0 -0.52 85.8 -101.0 -0.53 -0.7418 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D01 compound treatment 282.3 92.2 0.48 284.0 96.9 0.5 0.6961 0.9997 1927707 ChemDiv1_003939 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCSc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D02 compound treatment 283.7 93.6 0.49 286.8 99.7 0.52 0.7115 0.9996 1972208 ChemDiv1_003940 CCOc1ccc(Oc2cc(NC(=O)c3cnn4C(CC(Nc34)c5cccs5)C(F)(F)F)cc(c2)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D03 compound treatment 282.5 92.4 0.48 285.7 98.6 0.51 0.703 0.9995 1972209 ChemDiv1_003941 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3cccc(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D04 compound treatment 282.4 92.3 0.48 284.8 97.7 0.51 0.6994 0.9996 1924328 ChemDiv1_003942 COc1cc(cc(OC)c1OC)C2CC(n3ncc(C(=O)N4CCN(Cc5ccccc5)CC4)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D05 compound treatment 281.0 90.9 0.47 284.9 97.8 0.51 0.6946 0.9994 1949044 ChemDiv1_003943 CC(C)(C)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D06 compound treatment 283.8 93.7 0.49 283.0 95.9 0.5 0.6979 1.0 1924440 ChemDiv1_003944 CCOC(=O)c1sc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc5OCOc5c4)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D07 compound treatment 281.6 91.5 0.48 290.6 103.0 0.54 0.7177 0.9982 1925375 ChemDiv1_003945 CCOC(=O)CSCCOc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D08 compound treatment 280.7 90.6 0.47 285.7 98.6 0.51 0.6964 0.9992 1924351 ChemDiv1_003946 COc1ccccc1N2CCN(CC2)C(=O)c3cnn4C(CC(Nc34)c5ccc(Br)cc5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D09 compound treatment 278.7 88.6 0.46 284.3 97.2 0.51 0.6839 0.999 1489354 ChemDiv1_003947 Cc1ccc(cc1Cl)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D10 compound treatment 294.4 104.0 0.54 296.3 109.0 0.57 0.7859 0.9998 1972210 ChemDiv1_003948 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3sc4CCCCc4c3C#N)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D11 compound treatment 283.4 93.3 0.49 279.8 92.7 0.48 0.6847 1.0 1709596 ChemDiv1_003949 COc1cccc(c1)C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D12 compound treatment 280.2 90.1 0.47 284.6 97.5 0.51 0.6905 0.9993 1972211 ChemDiv1_003950 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccco4)C(F)(F)F)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D13 compound treatment 284.6 94.5 0.49 282.9 95.8 0.5 0.7005 1.0 1972212 ChemDiv1_003951 CC(C)OC(=O)c1c(NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C)sc3CC(C)CCc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D14 compound treatment 282.6 92.5 0.48 279.2 92.1 0.48 0.6795 1.0 1972213 ChemDiv1_003952 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4ccc(cc4)C(C)O)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D15 compound treatment 275.0 84.9 0.44 280.5 93.4 0.49 0.6563 0.9989 1972214 ChemDiv1_003953 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D16 compound treatment 279.8 89.7 0.47 274.3 87.2 0.45 0.6512 0.9999 1930322 ChemDiv1_003954 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4ccc5OCOc5c4)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D17 compound treatment 286.7 96.6 0.5 283.0 95.9 0.5 0.7086 1.0 1972215 ChemDiv1_003955 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3cccc(Cl)c3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D18 compound treatment 283.6 93.5 0.49 284.2 97.1 0.5 0.7016 0.9999 1972216 ChemDiv1_003956 Cc1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(C)cc4)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D19 compound treatment 281.5 91.4 0.48 278.4 91.3 0.47 0.6725 1.0 1930345 ChemDiv1_003957 COc1ccc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D20 compound treatment 280.4 90.3 0.47 280.1 93.0 0.48 0.6747 0.9999 1621854 ChemDiv1_003958 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(C)c4ccccc34)c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D21 compound treatment 279.1 89.0 0.46 277.7 90.6 0.47 0.6611 1.0 1924463 ChemDiv1_003959 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3nn4C(CC(Nc4c3Cl)c5cccs5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D22 compound treatment 306.4 116.0 0.61 296.0 109.0 0.57 0.8291 0.9994 1602163 ChemDiv1_003960 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3OC(=O)C)c(=O)n2C1c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D23 mock treatment 279.7 89.6 0.47 278.7 91.6 0.48 0.667 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 D24 mock treatment 76.2 -114.0 -0.59 76.4 -111.0 -0.58 -0.8272 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E01 compound treatment 286.7 96.6 0.5 287.5 100.0 0.52 0.7251 0.9998 1277264 ChemDiv1_003961 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(c3nc4ccccc4s3)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E02 compound treatment 285.6 95.5 0.5 286.4 99.3 0.52 0.717 0.9998 1385254 ChemDiv1_003962 COc1ccc(OC)c(Nc2nc3nonc3nc2Nc4cccc(Br)c4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E03 compound treatment 286.9 96.8 0.5 285.8 98.7 0.51 0.7196 1.0 1494085 ChemDiv1_003963 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E04 compound treatment 285.9 95.8 0.5 284.9 97.8 0.51 0.7126 1.0 1924459 ChemDiv1_003964 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E05 compound treatment 281.2 91.1 0.48 283.9 96.8 0.5 0.6916 0.9996 1972217 ChemDiv1_003965 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E06 compound treatment 286.2 96.1 0.5 284.7 97.6 0.51 0.713 1.0 1925598 ChemDiv1_003966 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2cccs2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E07 compound treatment 286.1 96.0 0.5 295.7 109.0 0.56 0.7531 0.9982 1607679 ChemDiv1_003967 CCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E08 compound treatment 282.9 92.8 0.48 285.4 98.3 0.51 0.7034 0.9996 1972218 ChemDiv1_003968 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E09 compound treatment 282.7 92.6 0.48 285.9 98.8 0.51 0.7045 0.9995 1972219 ChemDiv1_003969 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(Cl)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E10 compound treatment 280.9 90.8 0.47 277.0 89.9 0.47 0.6652 1.0 1230466 ChemDiv1_003970 CC(=O)Nc1cccc(c1)c2nc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E11 compound treatment 276.7 86.6 0.45 285.4 98.3 0.51 0.6805 0.9981 1216946 ChemDiv1_003971 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(O)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E12 compound treatment 277.4 87.3 0.46 281.9 94.8 0.49 0.6703 0.9992 1496354 ChemDiv1_003972 CC1CCN(CC1)c2nc(NCc3cccnc3)nc(n2)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E13 compound treatment 281.2 91.1 0.48 284.5 97.4 0.51 0.6938 0.9995 1297290 ChemDiv1_003973 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(C)cc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E14 compound treatment 281.7 91.6 0.48 283.6 96.5 0.5 0.6924 0.9997 1165062 ChemDiv1_003974 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E15 compound treatment 286.4 96.3 0.5 287.3 100.0 0.52 0.7233 0.9998 1674241 ChemDiv1_003975 CCOc1ccccc1C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E16 compound treatment 282.9 92.8 0.48 279.9 92.8 0.48 0.6832 1.0 1924592 ChemDiv1_003976 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccs2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E17 compound treatment 283.7 93.6 0.49 283.9 96.8 0.5 0.7008 0.9999 1972220 ChemDiv1_003977 CCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E18 compound treatment 285.5 95.4 0.5 286.7 99.6 0.52 0.7178 0.9998 1606919 ChemDiv1_003978 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4cc(C)c(C)cc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E19 compound treatment 288.9 98.8 0.52 293.9 107.0 0.56 0.7568 0.9993 1972221 ChemDiv1_003979 OC(=O)c1cccc(c1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E20 compound treatment 282.5 92.4 0.48 276.8 89.7 0.47 0.6703 0.9999 1972222 ChemDiv1_003980 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E21 compound treatment 320.6 130.0 0.68 323.8 137.0 0.71 0.9836 0.9998 1972223 ChemDiv1_003981 COc1cc(/C=C/2\Sc3ccccc3C2=O)c(Br)cc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E22 compound treatment 280.4 90.3 0.47 275.1 88.0 0.46 0.6563 0.9999 1972224 ChemDiv1_003982 OC(=O)c1n[nH]c(NC(=O)c2ccc(Br)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E23 mock treatment 280.9 90.8 0.47 280.1 93.0 0.48 0.6766 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 E24 mock treatment 83.0 -107.0 -0.56 80.7 -106.0 -0.55 -0.7863 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F01 compound treatment 281.6 91.5 0.48 289.5 102.0 0.53 0.7137 0.9985 1927496 ChemDiv1_003983 CC(C)(C)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F02 compound treatment 285.6 95.5 0.5 285.9 98.8 0.51 0.7152 0.9999 1972225 ChemDiv1_003984 [O-][N+](=O)c1cc(NC(=O)c2cnn3C(CC(Nc23)c4ccco4)C(F)(F)F)cc(Oc5ccc6CCCc6c5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F03 compound treatment 280.8 90.7 0.47 284.3 97.2 0.51 0.6916 0.9995 1972226 ChemDiv1_003985 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F04 compound treatment 282.0 91.9 0.48 282.8 95.7 0.5 0.6905 0.9998 1925366 ChemDiv1_003986 COc1cc(NC(=O)c2cnn3C(CC(Nc23)c4cc(OC)c(OC)c(OC)c4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F05 compound treatment 288.6 98.5 0.51 288.2 101.0 0.53 0.7347 0.9999 1948826 ChemDiv1_003987 Cc1ccc(OCCOc2ccc(Cl)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F06 compound treatment 281.9 91.8 0.48 283.4 96.3 0.5 0.6924 0.9998 1925361 ChemDiv1_003988 COc1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Br)cc4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F07 compound treatment 282.5 92.4 0.48 285.0 97.9 0.51 0.7005 0.9996 1926156 ChemDiv1_003989 CCOC(=O)CSCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F08 compound treatment 280.5 90.4 0.47 283.8 96.7 0.5 0.6887 0.9995 1925386 ChemDiv1_003990 COc1cc(NC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F09 compound treatment 281.6 91.5 0.48 283.5 96.4 0.5 0.6916 0.9997 1368321 ChemDiv1_003991 O=C1N(CN2CCOCC2)c3ccccc3C41OCCCO4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F10 compound treatment 283.3 93.2 0.49 289.4 102.0 0.53 0.7196 0.999 1972227 ChemDiv1_003992 CCOC(=O)c1c(NC(=O)c2nn3C(CC(Nc3c2Br)c4ccco4)C(F)(F)F)sc5CCCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F11 compound treatment 278.9 88.8 0.46 280.3 93.2 0.48 0.6699 0.9997 1972228 ChemDiv1_003993 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F12 compound treatment 279.8 89.7 0.47 283.9 96.8 0.5 0.6865 0.9993 1925345 ChemDiv1_003994 COc1ccc(cc1)C2CC(n3nc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F13 compound treatment 282.3 92.2 0.48 277.3 90.2 0.47 0.6714 0.9999 1972229 ChemDiv1_003995 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)NC4CCCCC4)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F14 compound treatment 283.3 93.2 0.49 285.1 98.0 0.51 0.7038 0.9997 1929817 ChemDiv1_003996 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F15 compound treatment 288.8 98.7 0.51 290.3 103.0 0.54 0.7432 0.9998 1972230 ChemDiv1_003997 FC(F)(F)c1c2CCc3ccccc3-c2nc4c(Cl)c(nn14)C(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F16 compound treatment 282.9 92.8 0.48 284.4 97.3 0.51 0.6997 0.9998 1972231 ChemDiv1_003998 COc1ccc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(OC)c(OC)c4)C(F)(F)F)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F17 compound treatment 280.6 90.5 0.47 279.4 92.3 0.48 0.6729 1.0 1931589 ChemDiv1_003999 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCCCN3CCOCC3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F18 compound treatment 278.7 88.6 0.46 277.4 90.3 0.47 0.6585 1.0 1972232 ChemDiv1_004000 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F19 compound treatment 291.8 102.0 0.53 298.1 111.0 0.58 0.7829 0.9991 1972233 ChemDiv1_004001 COc1ccc(CNC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F20 compound treatment 364.3 174.0 0.91 347.2 160.0 0.83 1.2308 0.999 1469829 ChemDiv1_004002 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F21 compound treatment 282.6 92.5 0.48 282.0 94.9 0.49 0.6898 0.9999 1972234 ChemDiv1_004003 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F22 compound treatment 284.1 94.0 0.49 282.2 95.1 0.49 0.6961 1.0 1520971 ChemDiv1_004004 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F23 mock treatment 281.6 91.5 0.48 280.5 93.4 0.49 0.6806 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 F24 mock treatment 78.4 -112.0 -0.58 76.2 -111.0 -0.58 -0.8199 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G01 compound treatment 289.3 99.2 0.52 283.6 96.5 0.5 0.7204 0.9999 1943454 ChemDiv1_004005 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G02 compound treatment 288.6 98.5 0.51 279.2 92.1 0.48 0.7016 0.9994 1934980 ChemDiv1_004006 Cc1cc(C)n(n1)c2nc3nonc3nc2Nc4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G03 compound treatment 284.7 94.6 0.49 283.5 96.4 0.5 0.7031 1.0 1946967 ChemDiv1_004007 CCOC(=O)CSc1nc2ccc(N)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G04 compound treatment 287.3 97.2 0.51 286.5 99.4 0.52 0.7237 1.0 1924638 ChemDiv1_004008 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(F)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G05 compound treatment 283.9 93.8 0.49 284.1 97.0 0.5 0.7023 0.9999 1972235 ChemDiv1_004009 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G06 compound treatment 282.7 92.6 0.48 286.3 99.2 0.52 0.706 0.9995 1972236 ChemDiv1_004010 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(C)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G07 compound treatment 295.8 106.0 0.55 297.3 110.0 0.57 0.7947 0.9998 1972237 ChemDiv1_004011 CCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G08 compound treatment 280.7 90.6 0.47 287.0 99.9 0.52 0.7012 0.9989 1972238 ChemDiv1_004012 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G09 compound treatment 282.2 92.1 0.48 287.3 100.0 0.52 0.7078 0.9992 1972239 ChemDiv1_004013 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(Br)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G10 compound treatment 283.0 92.9 0.48 281.2 94.1 0.49 0.6883 1.0 1972240 ChemDiv1_004014 O=C(Nc1nc2ccc3ccccc3c2o1)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G11 compound treatment 281.4 91.3 0.48 282.2 95.1 0.49 0.6861 0.9998 1147755 ChemDiv1_004015 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(O)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G12 compound treatment 280.6 90.5 0.47 285.7 98.6 0.51 0.696 0.9992 1692006 ChemDiv1_004016 COc1nc(NCc2ccccc2)nc(NCc3cccnc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G13 compound treatment 280.7 90.6 0.47 280.5 93.4 0.49 0.6773 0.9999 1972241 ChemDiv1_004017 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(c5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G14 compound treatment 278.0 87.9 0.46 281.4 94.3 0.49 0.6706 0.9994 1302123 ChemDiv1_004018 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G15 compound treatment 283.1 93.0 0.48 286.2 99.1 0.51 0.7071 0.9996 1445573 ChemDiv1_004019 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(Cl)cc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G16 compound treatment 279.0 88.9 0.46 281.1 94.0 0.49 0.6732 0.9997 1182604 ChemDiv1_004020 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(SC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G17 compound treatment 279.7 89.6 0.47 287.7 101.0 0.52 0.7001 0.9984 1972242 ChemDiv1_004021 CCCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G18 compound treatment 280.8 90.7 0.47 275.6 88.5 0.46 0.6596 0.9999 1972243 ChemDiv1_004022 [O-][N+](=O)c1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G19 compound treatment 307.0 117.0 0.61 307.7 121.0 0.63 0.8743 0.9999 1972244 ChemDiv1_004023 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc4C(=O)NC(=O)c4c3)c5cccc(c5)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G20 compound treatment 306.4 116.0 0.61 309.3 122.0 0.64 0.8779 0.9997 1972245 ChemDiv1_004024 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G21 compound treatment 280.1 90.0 0.47 280.1 93.0 0.48 0.6736 0.9999 1972246 ChemDiv1_004025 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1Oc3ccc(cc3C#N)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G22 compound treatment 279.5 89.4 0.47 277.8 90.7 0.47 0.6629 1.0 1229623 ChemDiv1_004026 COc1cc(cc(OC)c1OC)C(=O)Nc2nnc(CC(=O)NCc3ccccc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G23 mock treatment 281.5 91.4 0.48 279.9 92.8 0.48 0.678 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 G24 mock treatment 82.1 -108.0 -0.56 68.9 -118.0 -0.61 -0.833 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H01 compound treatment 289.7 99.6 0.52 285.8 98.7 0.51 0.73 1.0 1949048 ChemDiv1_004027 CC(C)(C)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=S)NC3=O)cc2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H02 compound treatment 284.7 94.6 0.49 286.1 99.0 0.51 0.7126 0.9998 1972247 ChemDiv1_004028 CCOC(=O)c1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccccc4)sc5CCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H03 compound treatment 285.1 95.0 0.5 286.1 99.0 0.51 0.7141 0.9998 1972248 ChemDiv1_004029 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H04 compound treatment 286.1 96.0 0.5 285.8 98.7 0.51 0.7167 0.9999 1972249 ChemDiv1_004030 COc1cc(cc(OC)c1OC)C2CC(n3ncc(C(=O)Nc4cc(Oc5ccc(F)cc5)cc(c4)[N+](=O)[O-])c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H05 compound treatment 286.8 96.7 0.5 284.8 97.7 0.51 0.7156 1.0 1948839 ChemDiv1_004031 Cc1ccc(OCCOc2ccc(Br)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H06 compound treatment 287.2 97.1 0.51 284.1 97.0 0.5 0.7145 1.0 1929838 ChemDiv1_004032 COc1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Br)cc4)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H07 compound treatment 281.3 91.2 0.48 281.6 94.5 0.49 0.6835 0.9999 1972250 ChemDiv1_004033 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)ccc1OCCBr 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H08 compound treatment 284.3 94.2 0.49 287.0 99.9 0.52 0.7145 0.9996 1972251 ChemDiv1_004034 CC(C)OC(=O)c1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)sc5CCCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H09 compound treatment 287.5 97.4 0.51 290.6 103.0 0.54 0.7395 0.9996 1346450 ChemDiv1_004035 OC1(C2CCc3ccccc3C2=O)C(=O)Nc4ccc(Br)cc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H10 compound treatment 285.7 95.6 0.5 285.0 97.9 0.51 0.7123 0.9999 1972252 ChemDiv1_004036 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H11 compound treatment 276.8 86.7 0.45 281.0 93.9 0.49 0.6647 0.9993 1972253 ChemDiv1_004037 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Br)c4ccccc4)C(F)(F)F)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H12 compound treatment 282.1 92.0 0.48 282.0 94.9 0.49 0.688 0.9999 1925357 ChemDiv1_004038 COc1ccc(cc1)C2CC(n3nc(C(=O)Nc4c(C)n(C)n(c5ccccc5)c4=O)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H13 compound treatment 280.4 90.3 0.47 283.1 96.0 0.5 0.6857 0.9996 1972254 ChemDiv1_004039 Cc1nn2c(cc(nc2c1C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)c5ccc(Cl)cc5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H14 compound treatment 279.8 89.7 0.47 283.6 96.5 0.5 0.6854 0.9994 1972255 ChemDiv1_004040 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4cccnc4Cl)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H15 compound treatment 286.7 96.6 0.5 279.2 92.1 0.48 0.6946 0.9997 1925262 ChemDiv1_004041 CCOC(=O)c1sc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4cccs4)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H16 compound treatment 297.4 107.0 0.56 298.1 111.0 0.58 0.8036 0.9999 1972256 ChemDiv1_004042 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4cccc(c4)C(C)O)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H17 compound treatment 278.5 88.4 0.46 282.9 95.8 0.5 0.678 0.9993 1972257 ChemDiv1_004043 Cc1ccc(O)c(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H18 compound treatment 280.9 90.8 0.47 276.8 89.7 0.47 0.6644 1.0 1930361 ChemDiv1_004044 COc1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Cl)cc4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H19 compound treatment 283.5 93.4 0.49 286.1 99.0 0.51 0.7082 0.9996 1929903 ChemDiv1_004045 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3ccc4OCOc4c3)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H20 compound treatment 294.1 104.0 0.54 288.1 101.0 0.52 0.7546 0.9999 1442665 ChemDiv1_004046 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H21 compound treatment 286.5 96.4 0.5 287.9 101.0 0.52 0.7259 0.9998 1929948 ChemDiv1_004047 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4cccs4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H22 compound treatment 290.7 101.0 0.52 290.2 103.0 0.54 0.7498 0.9999 1296152 ChemDiv1_004048 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(C)cc3)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H23 mock treatment 282.4 92.3 0.48 284.2 97.1 0.5 0.6972 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 H24 mock treatment 81.2 -109.0 -0.57 84.4 -103.0 -0.53 -0.7794 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I01 compound treatment 283.5 93.4 0.49 282.8 95.7 0.5 0.6961 0.9999 1226264 ChemDiv1_004049 COc1ccc(cc1OC)C(=O)Nc2cc(ccc2C)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I02 compound treatment 286.4 96.3 0.5 284.5 97.4 0.51 0.713 1.0 1500171 ChemDiv1_004050 CCOC(=O)c1ccc(Nc2nc3nonc3nc2NC(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I03 compound treatment 282.3 92.2 0.48 285.0 97.9 0.51 0.6997 0.9996 1972258 ChemDiv1_004051 Nc1ccc2nc(SCC(=O)c3ccc(Br)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I04 compound treatment 282.8 92.7 0.48 282.0 94.9 0.49 0.6905 1.0 1924497 ChemDiv1_004052 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccco2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I05 compound treatment 283.0 92.9 0.48 280.3 93.2 0.48 0.685 1.0 1972259 ChemDiv1_004053 Clc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I06 compound treatment 286.1 96.0 0.5 285.2 98.1 0.51 0.7145 1.0 1924502 ChemDiv1_004054 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccccc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I07 compound treatment 286.7 96.6 0.5 288.8 102.0 0.53 0.7299 0.9997 1972260 ChemDiv1_004055 C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56)c7ccccc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I08 compound treatment 280.1 90.0 0.47 279.7 92.6 0.48 0.6721 0.9999 1972261 ChemDiv1_004056 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I09 compound treatment 289.9 99.8 0.52 283.6 96.5 0.5 0.7226 0.9998 1972262 ChemDiv1_004057 Brc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I10 compound treatment 282.8 92.7 0.48 288.8 102.0 0.53 0.7155 0.999 1972263 ChemDiv1_004058 O=C(Nc1nc2c(ccc3ccccc23)o1)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I11 compound treatment 283.9 93.8 0.49 281.8 94.7 0.49 0.6939 1.0 1948838 ChemDiv1_004059 FC(F)(F)c1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I12 compound treatment 282.0 91.9 0.48 284.2 97.1 0.5 0.6957 0.9997 1636058 ChemDiv1_004060 COc1nc(NCc2cccnc2)nc(n1)N3CCSCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I13 compound treatment 283.3 93.2 0.49 281.5 94.4 0.49 0.6906 1.0 1197458 ChemDiv1_004061 CCOc1cccc(c1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I14 compound treatment 277.5 87.4 0.46 279.4 92.3 0.48 0.6614 0.9997 1128810 ChemDiv1_004062 CCOc1cc(cc(Br)c1O)C2NC(=O)N(C)C(=C2C(=O)OCCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I15 compound treatment 279.4 89.3 0.47 281.2 94.1 0.49 0.6751 0.9997 1927336 ChemDiv1_004063 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3cc(ccc3C)[N+](=O)[O-])c4cccc(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I16 compound treatment 294.7 105.0 0.55 293.2 106.0 0.55 0.7756 1.0 1122164 ChemDiv1_004064 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccc(OC)cc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I17 compound treatment 281.8 91.7 0.48 284.1 97.0 0.5 0.6946 0.9997 1972264 ChemDiv1_004065 CCOC(=O)c1cccc(c1)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I18 compound treatment 280.1 90.0 0.47 276.9 89.8 0.47 0.6618 1.0 1972265 ChemDiv1_004066 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I19 compound treatment 391.1 201.0 1.05 395.2 208.0 1.08 1.5061 0.9999 1946395 ChemDiv1_004067 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I20 compound treatment 286.0 95.9 0.5 290.3 103.0 0.54 0.7329 0.9994 1972266 ChemDiv1_004068 [O-][N+](=O)c1ccc(C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I21 compound treatment 296.6 106.0 0.56 300.1 113.0 0.59 0.808 0.9996 1317134 ChemDiv1_004069 CC1CCN(CC1)c2nc3nonc3nc2Nc4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I22 compound treatment 279.0 88.9 0.46 273.2 86.1 0.45 0.6442 0.9998 1599323 ChemDiv1_004070 Brc1ccc(OCc2nnc(NC(=O)C3(CC4CC5CC(C4)C3)C5)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I23 mock treatment 279.7 89.6 0.47 277.8 90.7 0.47 0.6637 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 I24 mock treatment 76.9 -113.0 -0.59 78.8 -108.0 -0.56 -0.8158 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J01 compound treatment 282.3 92.2 0.48 285.3 98.2 0.51 0.7008 0.9996 1972267 ChemDiv1_004071 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J02 compound treatment 287.6 97.5 0.51 286.8 99.7 0.52 0.7259 1.0 1972268 ChemDiv1_004072 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3cc4NC(CC(n4n3)C(F)(F)F)c5ccco5)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J03 compound treatment 286.1 96.0 0.5 286.4 99.3 0.52 0.7189 0.9999 1925364 ChemDiv1_004073 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Br)c1OCCOc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J04 compound treatment 282.6 92.5 0.48 284.8 97.7 0.51 0.7001 0.9997 1972269 ChemDiv1_004074 CCOC(=O)c1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc5OCOc5c4)C(F)(F)F)sc6CCCc16 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J05 compound treatment 280.6 90.5 0.47 284.8 97.7 0.51 0.6927 0.9993 1925297 ChemDiv1_004075 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J06 compound treatment 288.2 98.1 0.51 284.5 97.4 0.51 0.7197 1.0 1925323 ChemDiv1_004076 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)Nc3ccc(Cl)c(Cl)c3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J07 compound treatment 281.2 91.1 0.48 287.7 101.0 0.52 0.7056 0.9989 1972270 ChemDiv1_004077 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OCCBr)cc3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J08 compound treatment 291.6 101.0 0.53 285.7 98.6 0.51 0.7366 0.9999 1972271 ChemDiv1_004078 CC(C)c1ccc(C)cc1Oc2cc(NC(=O)c3cnn4C(CC(Nc34)c5ccc(Br)cc5)C(F)(F)F)cc(c2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J09 compound treatment 281.7 91.6 0.48 286.7 99.6 0.52 0.7038 0.9992 1972272 ChemDiv1_004079 Cc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccccc3F)CC2)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J10 compound treatment 283.2 93.1 0.49 283.0 95.9 0.5 0.6957 0.9999 1929960 ChemDiv1_004080 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J11 compound treatment 283.1 93.0 0.48 284.6 97.5 0.51 0.7012 0.9998 1923564 ChemDiv1_004081 Cc1c(Br)c(nn1CC(=O)Nc2cc(ccc2Cl)C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J12 compound treatment 281.1 91.0 0.47 281.0 93.9 0.49 0.6806 0.9999 1924393 ChemDiv1_004082 Fc1ccc(cc1)C2CC(n3nc(C(=O)N4CCN(Cc5ccccc5)CC4)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J13 compound treatment 278.0 87.9 0.46 281.4 94.3 0.49 0.6706 0.9994 1972273 ChemDiv1_004083 COc1ccc(cc1)c2cc(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J14 compound treatment 279.9 89.8 0.47 282.9 95.8 0.5 0.6832 0.9995 1925358 ChemDiv1_004084 COc1ccc(cc1OC)C2CC(n3nc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J15 compound treatment 280.6 90.5 0.47 281.4 94.3 0.49 0.6802 0.9998 1929792 ChemDiv1_004085 COc1ccc(cc1)C2CC(n3nc(C(=O)NCc4ccco4)c(Br)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J16 compound treatment 285.7 95.6 0.5 286.7 99.6 0.52 0.7185 0.9998 1930421 ChemDiv1_004086 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4ccc(F)cc4F)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J17 compound treatment 294.1 104.0 0.54 292.6 105.0 0.55 0.7712 1.0 1972274 ChemDiv1_004087 CC(O)c1ccc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J18 compound treatment 287.8 97.7 0.51 281.9 94.8 0.49 0.7086 0.9999 1784167 ChemDiv1_004088 Cc1c(Cl)c(nn1CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J19 compound treatment 312.2 122.0 0.64 311.3 124.0 0.65 0.9067 1.0 1931606 ChemDiv1_004089 CSc1ccccc1NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J20 compound treatment 288.8 98.7 0.51 288.3 101.0 0.53 0.7358 0.9999 1416027 ChemDiv1_004090 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(C)c4ccccc34)c(=O)n2C1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J21 compound treatment 289.4 99.3 0.52 287.2 100.0 0.52 0.734 1.0 1930268 ChemDiv1_004091 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4cccs4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J22 compound treatment 309.9 120.0 0.62 298.3 111.0 0.58 0.8504 0.9992 1505306 ChemDiv1_004092 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J23 mock treatment 284.3 94.2 0.49 277.3 90.2 0.47 0.6788 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 J24 mock treatment 79.6 -111.0 -0.58 78.5 -109.0 -0.56 -0.807 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K01 compound treatment 287.6 97.5 0.51 283.3 96.2 0.5 0.713 1.0 1445027 ChemDiv1_004093 CCOc1ccc(cc1)n2nc3ccc(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K02 compound treatment 283.0 92.9 0.48 277.4 90.3 0.47 0.6744 0.9999 1431787 ChemDiv1_004094 CN1CCN(CC1)c2nc3nonc3nc2Nc4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K03 compound treatment 286.0 95.9 0.5 284.4 97.3 0.51 0.7112 1.0 1972275 ChemDiv1_004095 CCCCCCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K04 compound treatment 287.1 97.0 0.51 285.7 98.6 0.51 0.72 1.0 1925666 ChemDiv1_004096 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K05 compound treatment 282.4 92.3 0.48 285.1 98.0 0.51 0.7005 0.9996 1972276 ChemDiv1_004097 COc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K06 compound treatment 285.1 95.0 0.5 282.3 95.2 0.49 0.7001 1.0 1924471 ChemDiv1_004098 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K07 compound treatment 285.1 95.0 0.5 285.9 98.8 0.51 0.7134 0.9998 1972277 ChemDiv1_004099 O=C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K08 compound treatment 285.7 95.6 0.5 286.0 98.9 0.51 0.7159 0.9999 1374228 ChemDiv1_004100 COc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(OC)c(OC)c3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K09 compound treatment 283.5 93.4 0.49 290.1 103.0 0.54 0.7229 0.9989 1972278 ChemDiv1_004101 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccc(Br)cc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K10 compound treatment 298.9 109.0 0.57 298.6 111.0 0.58 0.8109 0.9999 1972279 ChemDiv1_004102 CCN(CC)c1ccc(/C=C\2/Sc3c(ccc4ccccc34)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K11 compound treatment 283.1 93.0 0.48 282.6 95.5 0.5 0.6939 0.9999 1655566 ChemDiv1_004103 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K12 compound treatment 279.1 89.0 0.46 286.7 99.6 0.52 0.6942 0.9985 1313445 ChemDiv1_004104 C(Nc1nc(NCc2ccccc2)nc(n1)N3CCOCC3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K13 compound treatment 280.4 90.3 0.47 284.9 97.8 0.51 0.6924 0.9993 1972280 ChemDiv1_004105 COC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K14 compound treatment 284.2 94.1 0.49 280.7 93.6 0.49 0.6909 1.0 1972281 ChemDiv1_004106 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc4OCOc4cc3Cl)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K15 compound treatment 280.3 90.2 0.47 281.3 94.2 0.49 0.6788 0.9998 1972282 ChemDiv1_004107 COc1ccc(c2ccc(/C=C\3/C(=NN(C3=O)c4ccc(cc4)S(=O)(=O)N)C)o2)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K16 compound treatment 278.7 88.6 0.46 278.1 91.0 0.47 0.6611 0.9999 1536976 ChemDiv1_004108 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)cc5Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K17 compound treatment 288.3 98.2 0.51 292.0 105.0 0.55 0.7476 0.9995 1972283 ChemDiv1_004109 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccccc3C(=O)O)c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K18 compound treatment 297.7 108.0 0.56 296.0 109.0 0.57 0.797 1.0 1166040 ChemDiv1_004110 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)C4CCC(CC4)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K19 compound treatment 280.4 90.3 0.47 279.4 92.3 0.48 0.6721 1.0 1972284 ChemDiv1_004111 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(C)cc3[N+](=O)[O-])c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K20 compound treatment 283.9 93.8 0.49 275.9 88.8 0.46 0.6722 0.9996 1972285 ChemDiv1_004112 [O-][N+](=O)c1ccc(CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K21 compound treatment 286.1 96.0 0.5 283.2 96.1 0.5 0.7071 1.0 1291327 ChemDiv1_004113 COc1ccc(OC)c(Nc2nc3nonc3nc2N4CCCC(C)C4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K22 compound treatment 281.3 91.2 0.48 278.7 91.6 0.48 0.6729 1.0 1972286 ChemDiv1_004114 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OS(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K23 mock treatment 281.9 91.8 0.48 280.4 93.3 0.48 0.6813 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 K24 mock treatment 72.1 -118.0 -0.62 77.7 -109.0 -0.57 -0.8376 -0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L01 compound treatment 282.1 92.0 0.48 287.4 100.0 0.52 0.7078 0.9991 1925377 ChemDiv1_004115 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(cc3)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L02 compound treatment 285.3 95.2 0.5 285.3 98.2 0.51 0.7119 0.9999 1972287 ChemDiv1_004116 CCOC(=O)c1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccco4)sc5CCCCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L03 compound treatment 281.9 91.8 0.48 286.0 98.9 0.51 0.7019 0.9994 1972288 ChemDiv1_004117 COc1ccccc1OCCOc2c(Br)cc(C=C3C(=O)NC(=S)NC3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L04 compound treatment 282.4 92.3 0.48 284.3 97.2 0.51 0.6975 0.9997 1972289 ChemDiv1_004118 Cc1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc5OCOc5c4)C(F)(F)F)c(=O)n(c6ccccc6)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L05 compound treatment 282.2 92.1 0.48 280.9 93.8 0.49 0.6843 1.0 1972290 ChemDiv1_004119 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L06 compound treatment 286.1 96.0 0.5 284.0 96.9 0.5 0.7101 1.0 1972291 ChemDiv1_004120 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)Nc3ccc(Br)cc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L07 compound treatment 281.2 91.1 0.48 286.3 99.2 0.52 0.7004 0.9992 1948686 ChemDiv1_004121 [O-][N+](=O)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L08 compound treatment 278.8 88.7 0.46 286.4 99.3 0.52 0.692 0.9985 1972292 ChemDiv1_004122 CN1CCN(CC1)C(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(Br)cc4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L09 compound treatment 281.3 91.2 0.48 281.1 94.0 0.49 0.6817 0.9999 1972293 ChemDiv1_004123 Cc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(F)cc3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L10 compound treatment 282.9 92.8 0.48 283.6 96.5 0.5 0.6968 0.9998 1931602 ChemDiv1_004124 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)Nc3ccc4OCOc4c3)c5ccc(Cl)c(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L11 compound treatment 281.4 91.3 0.48 284.1 97.0 0.5 0.6931 0.9996 1972294 ChemDiv1_004125 FC(F)(F)c1cc(nc2cc(nn12)C(=O)N3CCN(CC3)c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L12 compound treatment 280.4 90.3 0.47 277.5 90.4 0.47 0.6652 1.0 1972295 ChemDiv1_004126 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L13 compound treatment 281.3 91.2 0.48 282.6 95.5 0.5 0.6872 0.9998 1928370 ChemDiv1_004127 COc1ccc(cc1)c2cc(n3nc(C(=O)NCCCn4ccnc4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L14 compound treatment 278.6 88.5 0.46 279.9 92.8 0.48 0.6673 0.9998 1929893 ChemDiv1_004128 COc1ccc(cc1OC)C2CC(n3nc(C(=O)N4CCN(CC4)c5ccccc5)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L15 compound treatment 282.7 92.6 0.48 283.0 95.9 0.5 0.6939 0.9999 1972296 ChemDiv1_004129 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L16 compound treatment 280.8 90.7 0.47 281.4 94.3 0.49 0.681 0.9998 1925296 ChemDiv1_004130 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(OC)c(OC)c4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L17 compound treatment 282.5 92.4 0.48 282.3 95.2 0.49 0.6905 0.9999 1972297 ChemDiv1_004131 Fc1ccc(CNC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L18 compound treatment 289.2 99.1 0.52 286.5 99.4 0.52 0.7307 1.0 1948899 ChemDiv1_004132 Cc1c(Br)c(nn1CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L19 compound treatment 278.2 88.1 0.46 283.2 96.1 0.5 0.678 0.9991 1972298 ChemDiv1_004133 CC(NC(=O)c1nn2C(CC(Nc2c1Br)c3cccs3)C(F)(F)F)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L20 compound treatment 279.1 89.0 0.46 280.2 93.1 0.48 0.6703 0.9998 1286457 ChemDiv1_004134 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L21 compound treatment 279.1 89.0 0.46 278.5 91.4 0.47 0.664 0.9999 1972299 ChemDiv1_004135 COc1ccc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(OC)c(OC)c4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L22 compound treatment 284.4 94.3 0.49 283.2 96.1 0.5 0.7009 1.0 1246789 ChemDiv1_004136 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L23 mock treatment 284.5 94.4 0.49 280.3 93.2 0.48 0.6906 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 L24 mock treatment 85.0 -105.0 -0.55 79.7 -107.0 -0.56 -0.7826 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M01 compound treatment 285.2 95.1 0.5 285.1 98.0 0.51 0.7108 0.9999 1302769 ChemDiv1_004137 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M02 compound treatment 281.8 91.7 0.48 282.4 95.3 0.5 0.6883 0.9998 1427833 ChemDiv1_004138 Cc1ccc(Nc2nc3nonc3nc2Nc4ccc(O)cc4)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M03 compound treatment 286.9 96.8 0.5 285.7 98.6 0.51 0.7193 1.0 1972300 ChemDiv1_004139 C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M04 compound treatment 285.7 95.6 0.5 285.7 98.6 0.51 0.7148 0.9999 1167434 ChemDiv1_004140 CCOc1cc(ccc1OC(=O)C)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M05 compound treatment 302.2 112.0 0.58 283.4 96.3 0.5 0.7673 0.997 1972301 ChemDiv1_004141 Brc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M06 compound treatment 287.7 97.6 0.51 282.4 95.3 0.5 0.7101 0.9999 1972302 ChemDiv1_004142 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M07 compound treatment 285.0 94.9 0.49 284.2 97.1 0.5 0.7067 1.0 1972303 ChemDiv1_004143 Cc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M08 compound treatment 281.9 91.8 0.48 287.3 100.0 0.52 0.7067 0.9991 1508655 ChemDiv1_004144 COc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(cc3)C(C)(C)C)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M09 compound treatment 281.7 91.6 0.48 283.9 96.8 0.5 0.6935 0.9997 1972304 ChemDiv1_004145 Clc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccc(Br)cc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M10 compound treatment 286.4 96.3 0.5 286.7 99.6 0.52 0.7211 0.9999 1254762 ChemDiv1_004146 COc1ccc(Cl)cc1C(=O)Nc2ccc(c3nc4cc(Cl)ccc4o3)c(O)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M11 compound treatment 280.6 90.5 0.47 281.6 94.5 0.49 0.681 0.9998 1151136 ChemDiv1_004147 CCOc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M12 compound treatment 281.0 90.9 0.47 278.9 91.8 0.48 0.6725 1.0 1438925 ChemDiv1_004148 C(Nc1nc(nc(n1)N2CCOCC2)N3CCCCC3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M13 compound treatment 282.2 92.1 0.48 287.8 101.0 0.52 0.7097 0.9991 1232338 ChemDiv1_004149 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M14 compound treatment 281.5 91.4 0.48 282.3 95.2 0.49 0.6869 0.9998 1972305 ChemDiv1_004150 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(COc4c(F)c(F)c(F)c(F)c4F)c3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M15 compound treatment 282.0 91.9 0.48 281.4 94.3 0.49 0.6854 0.9999 1972306 ChemDiv1_004151 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc(Cl)c1OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M16 compound treatment 284.6 94.5 0.49 282.0 94.9 0.49 0.6972 1.0 1344009 ChemDiv1_004152 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccc(OC)cc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M17 compound treatment 289.5 99.4 0.52 284.4 97.3 0.51 0.7241 0.9999 1948909 ChemDiv1_004153 CCOc1c(Br)cc(/C=C\2/N=C(\OC2=O)/C=C/c3ccccc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M18 compound treatment 279.2 89.1 0.46 278.5 91.4 0.47 0.6644 0.9999 1972307 ChemDiv1_004154 Cc1c(Br)c(nn1CC(=O)Nc2ccc(Oc3ccc(Cl)cc3)cc2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M19 compound treatment 282.3 92.2 0.48 277.9 90.8 0.47 0.6736 1.0 1292810 ChemDiv1_004155 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M20 compound treatment 282.0 91.9 0.48 277.1 90.0 0.47 0.6696 0.9999 1972308 ChemDiv1_004156 CCCCOc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M21 compound treatment 286.3 96.2 0.5 283.2 96.1 0.5 0.7079 1.0 1283174 ChemDiv1_004157 Fc1ccc(Nc2nc3nonc3nc2N4CCC(Cc5ccccc5)CC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M22 compound treatment 279.6 89.5 0.47 279.4 92.3 0.48 0.6692 0.9999 1972309 ChemDiv1_004158 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M23 mock treatment 280.8 90.7 0.47 278.1 91.0 0.47 0.6688 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 M24 mock treatment 199.2 9.07 0.05 190.2 3.07 0.02 0.0448 0.8961 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N01 compound treatment 279.0 88.9 0.46 283.8 96.7 0.5 0.6831 0.9992 1948965 ChemDiv1_004159 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OS(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N02 compound treatment 288.2 98.1 0.51 285.8 98.7 0.51 0.7244 1.0 1972310 ChemDiv1_004160 CC(C)OC(=O)c1c(C)c(C)sc1NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N03 compound treatment 280.1 90.0 0.47 281.9 94.8 0.49 0.6802 0.9997 1948752 ChemDiv1_004161 CC(C)(C)c1ccc(OCCOc2cccc(C=C3C(=O)NC(=S)NC3=O)c2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N04 compound treatment 287.7 97.6 0.51 283.1 96.0 0.5 0.7127 0.9999 1924389 ChemDiv1_004162 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)c6ccc7OCOc7c6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N05 compound treatment 283.4 93.3 0.49 281.7 94.6 0.49 0.6917 1.0 1972311 ChemDiv1_004163 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N06 compound treatment 286.7 96.6 0.5 282.7 95.6 0.5 0.7075 1.0 1972312 ChemDiv1_004164 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)c6ccc(Br)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N07 compound treatment 283.3 93.2 0.49 286.3 99.2 0.52 0.7082 0.9996 1972313 ChemDiv1_004165 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccccc3OCCBr)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N08 compound treatment 282.2 92.1 0.48 281.3 94.2 0.49 0.6858 1.0 1972314 ChemDiv1_004166 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)NCCN3CCOCC3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N09 compound treatment 285.5 95.4 0.5 285.6 98.5 0.51 0.7137 0.9999 1972315 ChemDiv1_004167 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc(F)cc3)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N10 compound treatment 282.0 91.9 0.48 280.7 93.6 0.49 0.6828 1.0 1925256 ChemDiv1_004168 Cc1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Cl)c(Cl)c4)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N11 compound treatment 284.9 94.8 0.49 283.6 96.5 0.5 0.7042 1.0 1972316 ChemDiv1_004169 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)Nc3ccncc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N12 compound treatment 281.8 91.7 0.48 283.8 96.7 0.5 0.6935 0.9997 1925303 ChemDiv1_004170 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(Cl)cc4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N13 compound treatment 284.7 94.6 0.49 282.4 95.3 0.5 0.699 1.0 1972317 ChemDiv1_004171 Fc1ccc(cc1)c2cc(n3nc(C(=O)NCc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N14 compound treatment 281.3 91.2 0.48 282.3 95.2 0.49 0.6861 0.9998 1930128 ChemDiv1_004172 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCCc4ccccc4)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N15 compound treatment 276.1 86.0 0.45 282.2 95.1 0.49 0.6666 0.9988 1972318 ChemDiv1_004173 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCCN3CCOCC3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N16 compound treatment 278.8 88.7 0.46 282.6 95.5 0.5 0.678 0.9994 1925242 ChemDiv1_004174 COc1ccc(cc1OC)C2CC(n3nc(C(=O)N4CCN(CC4)C(=O)c5ccccc5)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N17 compound treatment 289.1 99.0 0.52 289.5 102.0 0.53 0.7414 0.9999 1930437 ChemDiv1_004175 COc1ccc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N18 compound treatment 283.6 93.5 0.49 280.0 92.9 0.48 0.6861 1.0 1784170 ChemDiv1_004176 [O-][N+](=O)c1ncn(CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N19 compound treatment 279.4 89.3 0.47 279.2 92.1 0.48 0.6677 0.9999 1931586 ChemDiv1_004177 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)N3CCCc4ccccc34)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N20 compound treatment 284.3 94.2 0.49 286.4 99.3 0.52 0.7123 0.9997 1506316 ChemDiv1_004178 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3Cl)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N21 compound treatment 280.9 90.8 0.47 276.5 89.4 0.46 0.6633 1.0 1935617 ChemDiv1_004179 COc1ccc(cc1)C2CC(n3nc(cc3N2)C(=O)N4CCN(Cc5ccccc5)CC4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N22 compound treatment 284.4 94.3 0.49 279.1 92.0 0.48 0.6858 0.9999 1523266 ChemDiv1_004180 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC)c4ccccc34)c(=O)n2C1c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N23 mock treatment 280.5 90.4 0.47 280.6 93.5 0.49 0.6769 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 N24 mock treatment 196.3 6.17 0.03 189.3 2.17 0.01 0.0307 0.9013 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O01 compound treatment 285.6 95.5 0.5 282.3 95.2 0.49 0.702 1.0 1650522 ChemDiv1_004181 COc1cc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2)nc(OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O02 compound treatment 279.2 89.1 0.46 282.4 95.3 0.5 0.6787 0.9995 1539968 ChemDiv1_004182 COc1ccccc1Nc2nc3nonc3nc2N4CCCCC4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O03 compound treatment 284.1 94.0 0.49 285.4 98.3 0.51 0.7078 0.9998 1972319 ChemDiv1_004183 CCCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O04 compound treatment 281.5 91.4 0.48 282.9 95.8 0.5 0.6891 0.9998 1924458 ChemDiv1_004184 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O05 compound treatment 281.9 91.8 0.48 284.9 97.8 0.51 0.6979 0.9996 1972320 ChemDiv1_004185 CC(C)c1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O06 compound treatment 281.2 91.1 0.48 280.1 93.0 0.48 0.6777 1.0 1972321 ChemDiv1_004186 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5cc(ccc5Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O07 compound treatment 282.4 92.3 0.48 286.2 99.1 0.51 0.7045 0.9994 1972322 ChemDiv1_004187 Clc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O08 compound treatment 281.1 91.0 0.47 282.4 95.3 0.5 0.6857 0.9998 1364382 ChemDiv1_004188 CC(=O)Nc1ccc(cc1)c2nc(c3ccccc3)c4cc(C)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O09 compound treatment 284.2 94.1 0.49 286.3 99.2 0.52 0.7115 0.9997 1972323 ChemDiv1_004189 Brc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(Br)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O10 compound treatment 286.9 96.8 0.5 292.6 105.0 0.55 0.7446 0.9992 1387498 ChemDiv1_004190 CCN(CC)c1ccc(cc1)c2nc3cc(NC(=O)c4ccc(OC)c(OC)c4)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O11 compound treatment 279.7 89.6 0.47 286.5 99.4 0.52 0.6957 0.9987 1681030 ChemDiv1_004191 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc6OCOc6cc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O12 compound treatment 279.4 89.3 0.47 281.3 94.2 0.49 0.6754 0.9997 1972324 ChemDiv1_004192 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3Br)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O13 compound treatment 282.5 92.4 0.48 280.5 93.4 0.49 0.6839 1.0 1156745 ChemDiv1_004193 COc1cc(cc(OC)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O14 compound treatment 282.1 92.0 0.48 276.9 89.8 0.47 0.6692 0.9999 1738244 ChemDiv1_004194 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O15 compound treatment 278.2 88.1 0.46 282.5 95.4 0.5 0.6754 0.9993 1927357 ChemDiv1_004195 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc(Br)c1OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O16 compound treatment 280.9 90.8 0.47 280.5 93.4 0.49 0.678 0.9999 1924618 ChemDiv1_004196 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(O)c(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O17 compound treatment 283.1 93.0 0.48 280.4 93.3 0.48 0.6858 1.0 1186943 ChemDiv1_004197 Cn1c(SCc2ccccn2)nc3n(C)c(=O)n(C)c(=O)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O18 compound treatment 281.0 90.9 0.47 279.6 92.5 0.48 0.6751 1.0 1632083 ChemDiv1_004198 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(OC)ccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O19 compound treatment 285.1 95.0 0.5 277.8 90.7 0.47 0.6836 0.9997 1972325 ChemDiv1_004199 Cc1cc([N+](=O)[O-])c(cc1Cl)c2ccc(C=c3sc4nc5cc(C)c(C)cc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O20 compound treatment 275.6 85.5 0.45 275.3 88.2 0.46 0.6394 0.9999 1972326 ChemDiv1_004200 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(C)c([N+](=O)[O-])c4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O21 compound treatment 303.0 113.0 0.59 300.3 113.0 0.59 0.8323 1.0 1532775 ChemDiv1_004201 Clc1ccc(Sc2ccccc2C=c3sc4nc5ccccc5n4c3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O22 compound treatment 278.3 88.2 0.46 278.7 91.6 0.48 0.6618 0.9999 1972327 ChemDiv1_004202 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OS(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O23 mock treatment 285.8 95.7 0.5 279.5 92.4 0.48 0.6924 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 O24 mock treatment 101.0 -89.1 -0.46 94.7 -92.4 -0.48 -0.6685 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P01 compound treatment 282.6 92.5 0.48 288.7 102.0 0.53 0.7144 0.999 1948343 ChemDiv1_004203 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P02 compound treatment 283.8 93.7 0.49 283.4 96.3 0.5 0.6994 0.9999 1972328 ChemDiv1_004204 COc1ccc(cc1)C2CC(n3ncc(C(=O)Nc4sc5CCCCc5c4C(=O)OC(C)C)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P03 compound treatment 285.6 95.5 0.5 285.5 98.4 0.51 0.7137 0.9999 1949120 ChemDiv1_004205 CC(C)(C)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P04 compound treatment 291.1 101.0 0.53 287.1 100.0 0.52 0.7399 1.0 1972329 ChemDiv1_004206 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N(Cc3ccccc3)Cc4ccccc4)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P05 compound treatment 299.1 109.0 0.57 302.8 116.0 0.6 0.8271 0.9996 1972330 ChemDiv1_004207 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3cccc(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P06 compound treatment 284.0 93.9 0.49 285.5 98.4 0.51 0.7078 0.9998 1972331 ChemDiv1_004208 CCOC(=O)c1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)sc5CCCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P07 compound treatment 285.8 95.7 0.5 285.6 98.5 0.51 0.7148 0.9999 1949010 ChemDiv1_004209 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P08 compound treatment 279.8 89.7 0.47 284.7 97.6 0.51 0.6894 0.9992 1929910 ChemDiv1_004210 Cc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(Br)cc4)C(F)(F)F)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P09 compound treatment 278.2 88.1 0.46 283.6 96.5 0.5 0.6795 0.999 1972332 ChemDiv1_004211 Fc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccccc3F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P10 compound treatment 287.3 97.2 0.51 286.1 99.0 0.51 0.7222 1.0 1972333 ChemDiv1_004212 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccco4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P11 compound treatment 286.1 96.0 0.5 291.8 105.0 0.54 0.7387 0.9991 1778417 ChemDiv1_004213 Cc1cc(nc2cc(nn12)C(=O)Nc3cc(Oc4ccc(O)cc4)cc(c3)[N+](=O)[O-])c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P12 compound treatment 310.9 121.0 0.63 315.4 128.0 0.67 0.917 0.9996 1930318 ChemDiv1_004214 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(C)cc4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P13 compound treatment 283.2 93.1 0.49 284.0 96.9 0.5 0.6994 0.9998 1972334 ChemDiv1_004215 Fc1ccc(cc1)c2cc(n3nc(C(=O)Nc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P14 compound treatment 285.1 95.0 0.5 288.3 101.0 0.53 0.7222 0.9996 1972335 ChemDiv1_004216 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCCCn4ccnc4)c(Cl)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P15 compound treatment 284.5 94.4 0.49 282.1 95.0 0.49 0.6972 1.0 1972336 ChemDiv1_004217 [O-][N+](=O)c1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4cccs4)cc(Oc5ccccc5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P16 compound treatment 298.4 108.0 0.56 291.1 104.0 0.54 0.7815 0.9998 1972337 ChemDiv1_004218 Cc1ccc(cc1)C2CC(n3ncc(C(=O)N4CCN(CC4)C(c5ccccc5)c6ccccc6)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P17 compound treatment 281.8 91.7 0.48 282.7 95.6 0.5 0.6894 0.9998 1972338 ChemDiv1_004219 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCc3ccc(Cl)cc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P18 compound treatment 282.3 92.2 0.48 282.7 95.6 0.5 0.6913 0.9999 1972339 ChemDiv1_004220 OC(c1ccccc1)c2cc(Cl)ccc2NC(=O)c3cnn4C(CC(Nc34)c5cccs5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P19 compound treatment 283.2 93.1 0.49 282.2 95.1 0.49 0.6928 1.0 1931476 ChemDiv1_004221 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCCc3ccccc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P20 compound treatment 288.2 98.1 0.51 279.4 92.3 0.48 0.7009 0.9995 1410172 ChemDiv1_004222 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(OC)c3)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P21 compound treatment 283.0 92.9 0.48 279.2 92.1 0.48 0.681 1.0 1972340 ChemDiv1_004223 COc1ccc(cc1)C2CC(n3ncc(C(=O)N4CCN(CC4)C(c5ccccc5)c6ccccc6)c3N2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P22 compound treatment 279.8 89.7 0.47 276.9 89.8 0.47 0.6607 1.0 1972341 ChemDiv1_004224 COCCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccccc3)c4ccccc4)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P23 mock treatment 283.0 92.9 0.48 276.4 89.3 0.46 0.6707 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.598 P24 mock treatment 101.3 -88.8 -0.46 96.4 -90.7 -0.47 -0.6611 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A01 compound treatment 286.0 96.5 0.5 291.4 104.0 0.54 0.7373 0.9994 1972342 ChemDiv1_004225 CCOc1ccc(OCCSc2nc3ccccc3n2CC(=O)N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A02 compound treatment 281.0 91.5 0.48 282.0 94.4 0.49 0.6843 0.9999 1972343 ChemDiv1_004226 CCOC(=O)COc1ccc2c(=O)c(c3ccccc3OC)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A03 compound treatment 285.2 95.7 0.5 285.0 97.4 0.51 0.7109 1.0 1949172 ChemDiv1_004227 COc1ccc(cc1OC)c2nc3cc(NC(=O)c4ccc(cc4Cl)[N+](=O)[O-])ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A04 compound treatment 280.3 90.8 0.47 281.3 93.7 0.49 0.6792 0.9999 1972344 ChemDiv1_004228 Fc1ccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A05 compound treatment 286.0 96.5 0.5 285.0 97.4 0.51 0.7138 1.0 1972345 ChemDiv1_004229 COc1cc(/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A06 compound treatment 290.5 101.0 0.53 297.7 110.0 0.57 0.7771 0.9991 1357656 ChemDiv1_004230 OC(=O)CC(Nc1nc(nc2ccccc12)c3ccccc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A07 compound treatment 282.8 93.3 0.49 287.5 99.9 0.52 0.7112 0.9995 1972346 ChemDiv1_004231 Clc1ccccc1COc2cccc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A08 compound treatment 281.0 91.5 0.48 285.0 97.4 0.51 0.6954 0.9996 1944693 ChemDiv1_004232 Clc1cccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A09 compound treatment 376.2 187.0 0.97 377.5 190.0 0.99 1.3865 1.0 1972347 ChemDiv1_004233 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(OC)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A10 compound treatment 279.7 90.2 0.47 279.4 91.8 0.48 0.67 1.0 1950933 ChemDiv1_004234 CN(C)CCOC(=O)CN1C(=O)S/C(=C/c2ccc(Br)cc2)/C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A11 compound treatment 435.2 246.0 1.28 437.7 250.0 1.3 1.8254 1.0 1972348 ChemDiv1_004235 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(Cl)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A12 compound treatment 349.6 160.0 0.83 355.6 168.0 0.87 1.2079 0.9997 1972349 ChemDiv1_004236 CCOC(=O)c1c(N/C=C\2/Sc3ccccc3C2=O)scc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A13 compound treatment 281.9 92.3 0.48 285.1 97.5 0.51 0.6991 0.9997 1972350 ChemDiv1_004237 OC(=O)COc1cccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A14 compound treatment 394.4 205.0 1.07 392.5 205.0 1.07 1.5088 1.0 1972351 ChemDiv1_004238 CC(=O)c1ccc(N/C(=C\2/Sc3ccccc3C2=O)/C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A15 compound treatment 280.8 91.3 0.48 279.5 91.9 0.48 0.6744 1.0 1972352 ChemDiv1_004239 COc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A16 compound treatment 327.6 138.0 0.72 320.9 133.0 0.69 0.9992 0.9998 1972353 ChemDiv1_004240 CCC(=O)N(/C=C/1\Sc2ccccc2C1=O)c3cccc(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A17 compound treatment 290.1 101.0 0.52 294.3 107.0 0.55 0.7631 0.9996 1972354 ChemDiv1_004241 Clc1ccccc1/N=C/2\NC(=O)\C(=C/c3cc4OCOc4cc3Cl)\S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A18 compound treatment 303.9 114.0 0.6 293.3 106.0 0.55 0.8104 0.9992 1972355 ChemDiv1_004242 [O-][N+](=O)c1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A19 compound treatment 280.5 91.0 0.47 274.8 87.2 0.45 0.656 0.9997 1562080 ChemDiv1_004243 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5c(F)cccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A20 compound treatment 280.2 90.7 0.47 275.7 88.1 0.46 0.6582 0.9999 1972356 ChemDiv1_004244 Brc1ccc(cc1)c2nc3sc4CCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A21 compound treatment 275.2 85.7 0.45 275.6 88.0 0.46 0.6394 0.9999 1972357 ChemDiv1_004245 Cc1nc(SCC(=O)NC2CCCCC2)c3c4CCCCc4sc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A22 compound treatment 280.0 90.5 0.47 272.9 85.3 0.44 0.6472 0.9995 1972358 ChemDiv1_004246 CC(C)c1nc2sc(C)c(C)c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A23 mock treatment 281.9 92.3 0.48 283.3 95.7 0.5 0.6924 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 A24 mock treatment 77.6 -112.0 -0.58 78.6 -109.0 -0.57 -0.8135 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B01 compound treatment 281.7 92.2 0.48 286.0 98.4 0.51 0.7016 0.9995 1364506 ChemDiv1_004247 CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3ccccc3Br)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B02 compound treatment 280.7 91.2 0.48 280.2 92.6 0.48 0.6766 1.0 1972359 ChemDiv1_004248 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc([N+](=O)[O-])c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B03 compound treatment 286.8 97.3 0.51 283.5 95.9 0.5 0.7113 1.0 1972360 ChemDiv1_004249 CCOC(=O)c1c(N/C=C\2/N=C(OC2=O)c3ccco3)scc1c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B04 compound treatment 278.5 89.0 0.46 283.5 95.9 0.5 0.6806 0.9994 1972361 ChemDiv1_004250 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc4OCOc4cc3Br)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B05 compound treatment 279.5 90.0 0.47 282.8 95.2 0.49 0.6818 0.9996 1972362 ChemDiv1_004251 Cc1cc2c(=O)n(c3ccccc3)c(=S)[nH]c2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B06 compound treatment 285.3 95.8 0.5 282.4 94.8 0.49 0.7017 1.0 1136653 ChemDiv1_004252 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(SC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B07 compound treatment 279.1 89.5 0.47 281.2 93.6 0.49 0.6744 0.9998 1728289 ChemDiv1_004253 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4ccccc4Br)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B08 compound treatment 283.6 94.0 0.49 280.9 93.3 0.49 0.6899 1.0 1393024 ChemDiv1_004254 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)cc3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B09 compound treatment 282.8 93.3 0.49 282.3 94.7 0.49 0.6921 1.0 1550025 ChemDiv1_004255 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(Cl)cc5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B10 compound treatment 285.2 95.7 0.5 284.9 97.3 0.51 0.7105 1.0 1150805 ChemDiv1_004256 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B11 compound treatment 286.2 96.7 0.5 283.4 95.8 0.5 0.7087 1.0 1447214 ChemDiv1_004257 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc(Br)c5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B12 compound treatment 334.0 144.0 0.75 341.4 154.0 0.8 1.0982 0.9996 1244184 ChemDiv1_004258 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccc(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B13 compound treatment 279.2 89.7 0.47 281.4 93.8 0.49 0.6755 0.9998 1403876 ChemDiv1_004259 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(Br)cc5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B14 compound treatment 277.6 88.0 0.46 277.7 90.1 0.47 0.656 1.0 1123181 ChemDiv1_004260 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(cc3)C(=O)OC)c(=O)n2C1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B15 compound treatment 277.5 88.0 0.46 281.0 93.4 0.49 0.6678 0.9996 1407004 ChemDiv1_004261 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B16 compound treatment 280.5 91.0 0.47 282.0 94.4 0.49 0.6825 0.9999 1931096 ChemDiv1_004262 COc1ccc2ccccc2c1C3C(=C(C)N=c4sc(=Cc5cc(OC)c(OC)c(OC)c5)c(=O)n34)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B17 compound treatment 277.3 87.8 0.46 281.1 93.5 0.49 0.6674 0.9995 1722363 ChemDiv1_004263 CCCn1c2ccccc2c3nc4cc(OC)c(OC)cc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B18 compound treatment 279.8 90.3 0.47 281.9 94.3 0.49 0.6796 0.9998 1722870 ChemDiv1_004264 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccnc3)c(=O)n2C1c4c(OC)ccc5ccc(OC)cc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B19 compound treatment 280.2 90.7 0.47 275.8 88.2 0.46 0.6586 0.9999 1568825 ChemDiv1_004265 CCN(CC)CCn1c(NC(=O)C)nc2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B20 compound treatment 279.0 89.5 0.47 276.0 88.4 0.46 0.6549 1.0 1129597 ChemDiv1_004266 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)N2CCN(CC2)c3ccccc3)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B21 compound treatment 283.6 94.0 0.49 281.2 93.6 0.49 0.691 1.0 1972363 ChemDiv1_004267 Fc1ccccc1c2nc3sc4CCCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B22 compound treatment 280.9 91.3 0.48 273.3 85.7 0.45 0.652 0.9994 1944638 ChemDiv1_004268 [O-][N+](=O)c1cccc(c1)N(CC(=O)NCCSCc2ccccc2Cl)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B23 mock treatment 279.3 89.8 0.47 277.2 89.6 0.47 0.6604 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 B24 mock treatment 65.1 -124.0 -0.65 80.3 -107.0 -0.56 -0.8534 -0.9971 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C01 compound treatment 286.1 96.5 0.5 286.4 98.8 0.51 0.7193 1.0 1924665 ChemDiv1_004269 CCc1ccc(cc1)c2nn(c3cc(ccc3[N+](=O)[O-])N4CCOCC4)c(=O)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C02 compound treatment 282.9 93.3 0.49 283.7 96.1 0.5 0.6976 0.9999 1461496 ChemDiv1_004270 COc1cc(cc(OC)c1OC)c2cc(nc(SCC(=O)Nc3cc(C)on3)c2C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C03 compound treatment 298.4 109.0 0.57 297.6 110.0 0.57 0.8059 1.0 1972364 ChemDiv1_004271 COc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)ccc1Oc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C04 compound treatment 282.8 93.3 0.49 283.6 96.0 0.5 0.6969 0.9999 1972365 ChemDiv1_004272 CC/N=C/1\SC(CC(=O)Nc2ccccc2Cl)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C05 compound treatment 278.8 89.3 0.47 279.4 91.8 0.48 0.6667 0.9999 1563364 ChemDiv1_004273 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C06 compound treatment 283.2 93.7 0.49 283.5 95.9 0.5 0.698 0.9999 1972366 ChemDiv1_004274 Cc1c(NC(=O)CCN2C(=O)S/C(=C/c3ccc(C)cc3)/C2=O)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C07 compound treatment 280.8 91.3 0.48 280.5 92.9 0.48 0.6781 1.0 1972367 ChemDiv1_004275 CCOc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C08 compound treatment 284.2 94.7 0.49 282.6 95.0 0.49 0.6984 1.0 1972368 ChemDiv1_004276 COc1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C(=O)CCN4C(=O)\C(=C/c5ccc(OC)cc5)\SC4=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C09 compound treatment 290.3 101.0 0.53 293.3 106.0 0.55 0.7602 0.9998 1972369 ChemDiv1_004277 Brc1cc2OCOc2cc1/C=C\3/S/C(=N/c4ccccc4)/NC3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C10 compound treatment 281.0 91.5 0.48 279.5 91.9 0.48 0.6752 1.0 1697070 ChemDiv1_004278 Cc1ccccc1OCc2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C11 compound treatment 316.5 127.0 0.66 316.7 129.0 0.67 0.9428 1.0 1972370 ChemDiv1_004279 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C12 compound treatment 283.9 94.3 0.49 280.0 92.4 0.48 0.6877 0.9999 1972371 ChemDiv1_004280 O=C1/C(=C\NN2CCCCC2)/Sc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C13 compound treatment 281.3 91.8 0.48 284.4 96.8 0.5 0.6943 0.9997 1972372 ChemDiv1_004281 Fc1ccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C14 compound treatment 303.4 114.0 0.59 301.5 114.0 0.59 0.8386 1.0 1972373 ChemDiv1_004282 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccccc3Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C15 compound treatment 282.7 93.2 0.49 284.3 96.7 0.5 0.6991 0.9999 1972374 ChemDiv1_004283 [O-][N+](=O)c1cc(ccc1Oc2c(Br)cc(/C=C\3/NC(=S)NC3=O)cc2Br)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C16 compound treatment 277.2 87.7 0.46 275.5 87.9 0.46 0.6464 1.0 1972375 ChemDiv1_004284 CCC(=O)N(C)/C=C/1\Sc2ccccc2C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C17 compound treatment 278.4 88.8 0.46 282.0 94.4 0.49 0.6748 0.9996 1972376 ChemDiv1_004285 COc1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C18 compound treatment 377.9 188.0 0.98 370.4 183.0 0.95 1.3667 0.9999 1972377 ChemDiv1_004286 COc1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C19 compound treatment 279.6 90.0 0.47 278.5 90.9 0.47 0.6663 1.0 1972378 ChemDiv1_004287 Clc1ccccc1Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C20 compound treatment 279.3 89.8 0.47 277.9 90.3 0.47 0.663 1.0 1972379 ChemDiv1_004288 Cc1sc2nc(oc(=O)c2c1C)c3cccc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C21 compound treatment 279.6 90.0 0.47 276.2 88.6 0.46 0.6579 1.0 1972380 ChemDiv1_004289 Cc1cc2nnc(SCC(=O)Nc3ccccc3F)n2c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C22 compound treatment 277.4 87.8 0.46 279.4 91.8 0.48 0.6615 0.9998 1685242 ChemDiv1_004290 CC(C)(C)c1nc2scc(c3cccs3)c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C23 mock treatment 282.7 93.2 0.49 279.9 92.3 0.48 0.6829 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 C24 mock treatment 83.3 -106.0 -0.55 75.2 -112.0 -0.58 -0.805 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D01 compound treatment 281.7 92.2 0.48 283.2 95.6 0.5 0.6913 0.9999 1433674 ChemDiv1_004291 CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3cccc(Br)c3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D02 compound treatment 287.7 98.2 0.51 293.3 106.0 0.55 0.7506 0.9994 1972381 ChemDiv1_004292 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D03 compound treatment 299.6 110.0 0.57 289.3 102.0 0.53 0.7798 0.9992 1972382 ChemDiv1_004293 CC/1=NN(C(=O)\C1=C\Nc2cc(Br)ccc2O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D04 compound treatment 282.1 92.5 0.48 282.5 94.9 0.49 0.6902 0.9999 1972383 ChemDiv1_004294 Clc1cc(Cl)cc(c1)N2C(=O)/C(=C/c3ccc4OCOc4c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D05 compound treatment 278.5 89.0 0.46 281.1 93.5 0.49 0.6718 0.9997 1972384 ChemDiv1_004295 Cc1ccc(c2csc3[nH]c(=S)[nH]c(=O)c23)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D06 compound treatment 319.7 130.0 0.68 333.5 146.0 0.76 1.0164 0.9985 1684781 ChemDiv1_004296 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5cc(OC)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D07 compound treatment 278.6 89.0 0.46 281.0 93.4 0.49 0.6718 0.9998 1972385 ChemDiv1_004297 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccccc3Br)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D08 compound treatment 277.7 88.2 0.46 280.1 92.5 0.48 0.6652 0.9997 1185537 ChemDiv1_004298 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC)cc3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D09 compound treatment 281.2 91.7 0.48 278.4 90.8 0.47 0.6719 1.0 1510072 ChemDiv1_004299 COc1ccc(CCNc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4F)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D10 compound treatment 300.5 111.0 0.58 311.5 124.0 0.64 0.8647 0.9986 1632828 ChemDiv1_004300 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D11 compound treatment 277.6 88.0 0.46 280.3 92.7 0.48 0.6656 0.9997 1221068 ChemDiv1_004301 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4ccc(Br)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D12 compound treatment 334.1 145.0 0.75 349.9 162.0 0.84 1.1298 0.9984 1592894 ChemDiv1_004302 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D13 compound treatment 279.3 89.8 0.47 284.6 97.0 0.5 0.6876 0.9993 1972386 ChemDiv1_004303 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccc(Cl)cc3Cl)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D14 compound treatment 309.0 119.0 0.62 321.9 134.0 0.7 0.9343 0.9984 1972387 ChemDiv1_004304 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D15 compound treatment 282.5 93.0 0.48 279.8 92.2 0.48 0.6818 1.0 1549327 ChemDiv1_004305 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4c(Cl)cccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D16 compound treatment 287.0 97.5 0.51 284.8 97.2 0.51 0.7168 1.0 1972388 ChemDiv1_004306 COc1ccc2ccc(OC)c(C=c3sc4=NC(=C(C(c5ccccc5OC)n4c3=O)C(=O)C)C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D17 compound treatment 282.6 93.0 0.49 278.4 90.8 0.47 0.677 0.9999 1173148 ChemDiv1_004307 CCCCn1c2ccccc2c3nc4cc(OC)c(OC)cc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D18 compound treatment 280.6 91.0 0.47 279.5 91.9 0.48 0.6737 1.0 1972389 ChemDiv1_004308 COc1ccc(cc1)C(=O)NN2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D19 compound treatment 280.1 90.5 0.47 276.8 89.2 0.46 0.6619 1.0 1141158 ChemDiv1_004309 CN(C)CCCn1c(NC(=O)C)nc2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D20 compound treatment 277.7 88.2 0.46 275.0 87.4 0.45 0.6464 1.0 1972390 ChemDiv1_004310 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSc2ccccn2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D21 compound treatment 285.2 95.7 0.5 276.9 89.3 0.46 0.6811 0.9994 1730319 ChemDiv1_004311 Cc1cccc(c1)c2nc3sc4CCCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D22 compound treatment 281.5 92.0 0.48 275.9 88.3 0.46 0.6638 0.9998 1781251 ChemDiv1_004312 [O-][N+](=O)c1cccc(c1)N(CC(=O)N(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D23 mock treatment 282.8 93.3 0.49 281.8 94.2 0.49 0.6903 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 D24 mock treatment 79.4 -110.0 -0.57 81.3 -106.0 -0.55 -0.797 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E01 compound treatment 273.8 84.3 0.44 269.6 82.0 0.43 0.6122 0.9999 1972391 ChemDiv1_004313 OC(=O)c1cc(NC(=O)c2cccc(c2)N3C(=O)c4cccc5c(ccc(C3=O)c45)[N+](=O)[O-])cc(c1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E02 compound treatment 282.0 92.5 0.48 282.8 95.2 0.49 0.691 0.9999 1639906 ChemDiv1_004314 COc1cc(cc(OC)c1OC)c2cc(nc(SCC(=O)Nc3ncccn3)c2C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E03 compound treatment 286.2 96.7 0.5 281.5 93.9 0.49 0.7017 0.9999 1375823 ChemDiv1_004315 Cc1cc(C)n(n1)c2nc(nc(n2)N3CCOCC3)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E04 compound treatment 269.7 80.2 0.42 283.0 95.4 0.5 0.6463 0.9964 1972392 ChemDiv1_004316 CC/N=C\1/SC(CC(=O)Nc2cccc(c2)C(F)(F)F)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E05 compound treatment 286.5 97.0 0.51 284.2 96.6 0.5 0.7127 1.0 1784721 ChemDiv1_004317 COc1ccc(c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E06 compound treatment 280.4 90.8 0.47 282.9 95.3 0.5 0.6854 0.9998 1936624 ChemDiv1_004318 CCOC(=O)c1ccc(NC(=O)CCCN2C(=O)/C(=C/c3ccc(OC)cc3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E07 compound treatment 279.1 89.5 0.47 282.6 95.0 0.49 0.6795 0.9996 1944202 ChemDiv1_004319 [O-][N+](=O)c1ccc(Cl)c(c1)c2ccc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E08 compound treatment 302.0 112.0 0.59 303.4 116.0 0.6 0.8405 0.9999 1947414 ChemDiv1_004320 [O-][N+](=O)c1cc2OCOc2cc1/C=C/3\SC(=S)N(NC(=O)c4ccccc4Cl)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E09 compound treatment 288.5 99.0 0.52 290.4 103.0 0.53 0.7429 0.9998 1972393 ChemDiv1_004321 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E10 compound treatment 285.0 95.5 0.5 286.2 98.6 0.51 0.7145 0.9999 1972394 ChemDiv1_004322 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccc(Cl)cc3Cl)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E11 compound treatment 288.3 98.8 0.52 293.2 106.0 0.55 0.7524 0.9995 1972395 ChemDiv1_004323 COc1ccc2ccccc2c1/C=C\3/S/C(=N/c4ccccc4)/NC3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E12 compound treatment 280.0 90.5 0.47 284.4 96.8 0.5 0.6895 0.9995 1972396 ChemDiv1_004324 Clc1ncccc1C(=O)Oc2ccccc2/C=C/3\Sc4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E13 compound treatment 280.5 91.0 0.47 284.4 96.8 0.5 0.6913 0.9996 1972397 ChemDiv1_004325 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1Oc5nc(nc(n5)N6CCOCC6)N7CCOCC7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E14 compound treatment 318.7 129.0 0.67 308.1 121.0 0.63 0.9193 0.9993 1972398 ChemDiv1_004326 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E15 compound treatment 284.3 94.8 0.49 285.6 98.0 0.51 0.7098 0.9999 1972399 ChemDiv1_004327 Clc1ccc(COc2ccc(/C=C\3/NC(=S)NC3=O)cc2)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E16 compound treatment 278.8 89.3 0.47 277.7 90.1 0.47 0.6604 1.0 1972400 ChemDiv1_004328 CCC(=O)N(Cc1ccccc1)/C=C/2\Sc3ccccc3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E17 compound treatment 281.6 92.0 0.48 282.7 95.1 0.49 0.6891 0.9999 1972401 ChemDiv1_004329 COc1ccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E18 compound treatment 277.5 88.0 0.46 278.4 90.8 0.47 0.6582 0.9999 1972402 ChemDiv1_004330 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E19 compound treatment 281.4 91.8 0.48 278.9 91.3 0.47 0.6744 1.0 1972403 ChemDiv1_004331 Clc1ccc(Cn2cc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E20 compound treatment 285.5 96.0 0.5 283.5 95.9 0.5 0.7065 1.0 1381477 ChemDiv1_004332 O=c1oc(nc2scc(c3cccs3)c12)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E21 compound treatment 280.9 91.3 0.48 278.6 91.0 0.47 0.6715 1.0 1972404 ChemDiv1_004333 O=C1N(CSc2ncnc3sc4CCCCc4c23)C(=O)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E22 compound treatment 278.0 88.5 0.46 274.1 86.5 0.45 0.6442 0.9999 1972405 ChemDiv1_004334 Cc1sc2nc(oc(=O)c2c1C)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E23 mock treatment 281.8 92.3 0.48 280.7 93.1 0.48 0.6825 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 E24 mock treatment 77.2 -112.0 -0.59 80.4 -107.0 -0.56 -0.8084 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F01 compound treatment 287.4 97.8 0.51 283.9 96.3 0.5 0.7149 1.0 1972406 ChemDiv1_004335 CCOC(=O)c1c(C)n(c2ccc(C)cc2C)c3ccc(OC(=O)/C=C/c4ccccc4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F02 compound treatment 299.0 109.0 0.57 299.3 112.0 0.58 0.8143 1.0 1928991 ChemDiv1_004336 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c(O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F03 compound treatment 278.0 88.5 0.46 281.3 93.7 0.49 0.6707 0.9996 1972407 ChemDiv1_004337 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)scc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F04 compound treatment 351.4 162.0 0.84 362.3 175.0 0.91 1.2392 0.9993 1494558 ChemDiv1_004338 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F05 compound treatment 280.0 90.5 0.47 282.4 94.8 0.49 0.6821 0.9998 1972408 ChemDiv1_004339 Brc1ccc(cc1)c2csc3[nH]c(=S)[nH]c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F06 compound treatment 283.6 94.0 0.49 283.6 96.0 0.5 0.6998 1.0 1487022 ChemDiv1_004340 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(C)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F07 compound treatment 286.2 96.7 0.5 282.0 94.4 0.49 0.7035 0.9999 1659447 ChemDiv1_004341 CC1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F08 compound treatment 398.9 209.0 1.09 385.4 198.0 1.03 1.4993 0.9995 1507573 ChemDiv1_004342 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F09 compound treatment 281.0 91.5 0.48 281.3 93.7 0.49 0.6818 0.9999 1678240 ChemDiv1_004343 COc1ccc(CCNc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(F)c4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F10 compound treatment 304.9 115.0 0.6 309.4 122.0 0.63 0.8732 0.9997 1282868 ChemDiv1_004344 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F11 compound treatment 282.1 92.5 0.48 282.8 95.2 0.49 0.6913 0.9999 1972409 ChemDiv1_004345 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccc(Br)cc3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F12 compound treatment 361.1 172.0 0.89 375.9 188.0 0.98 1.3249 0.999 1440544 ChemDiv1_004346 CCOC(=O)C1=C(C)N=c2sc(=Cc3c(C)[nH]c4ccccc34)c(=O)n2C1c5ccc(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F13 compound treatment 279.6 90.0 0.47 283.5 95.9 0.5 0.6847 0.9996 1253520 ChemDiv1_004347 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F14 compound treatment 282.7 93.2 0.49 281.7 94.1 0.49 0.6895 1.0 1972410 ChemDiv1_004348 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F15 compound treatment 276.3 86.8 0.45 276.2 88.6 0.46 0.6457 1.0 1256488 ChemDiv1_004349 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3c(Cl)cccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F16 compound treatment 281.5 92.0 0.48 283.0 95.4 0.5 0.6899 0.9999 1292167 ChemDiv1_004350 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(O)c3)c(=O)n2C1c4cc(Br)c(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F17 compound treatment 273.5 84.0 0.44 277.0 89.4 0.46 0.6383 0.9996 1327163 ChemDiv1_004351 COc1cc2nc3n(CCC(C)C)c4ccccc4c3nc2cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F18 compound treatment 278.0 88.5 0.46 280.7 93.1 0.48 0.6685 0.9997 1172234 ChemDiv1_004352 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(F)c(Cl)c2)S(=O)(=O)c3ccc(SC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F19 compound treatment 281.8 92.3 0.48 275.2 87.6 0.46 0.6623 0.9996 1727978 ChemDiv1_004353 Cc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCN4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F20 compound treatment 278.2 88.7 0.46 278.1 90.5 0.47 0.6597 1.0 1972411 ChemDiv1_004354 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSc2ccc(Cl)cc2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F21 compound treatment 278.9 89.3 0.47 279.9 92.3 0.48 0.6689 0.9999 1972412 ChemDiv1_004355 Cc1ccccc1c2nc3sc4CCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F22 compound treatment 278.5 89.0 0.46 276.9 89.3 0.46 0.6564 1.0 1120902 ChemDiv1_004356 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc(C)cc3)S(=O)(=O)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F23 mock treatment 282.7 93.2 0.49 280.4 92.8 0.48 0.6847 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 F24 mock treatment 91.2 -98.3 -0.51 81.0 -107.0 -0.55 -0.7546 -0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G01 compound treatment 277.2 87.7 0.46 276.1 88.5 0.46 0.6486 1.0 1470580 ChemDiv1_004357 OC(=O)c1ccc(cc1)S(=O)(=O)c2ccc3C(=O)N(C(=O)c4cccc2c43)c5cccc(O)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G02 compound treatment 284.2 94.7 0.49 285.3 97.7 0.51 0.7083 0.9999 1191919 ChemDiv1_004358 Cc1ccc(cc1)c2cc(nc(SCC(=O)Nc3ncccn3)c2C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G03 compound treatment 351.0 161.0 0.84 360.6 173.0 0.9 1.2315 0.9995 1972413 ChemDiv1_004359 COc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G04 compound treatment 284.9 95.3 0.5 279.2 91.6 0.48 0.6884 0.9998 1972414 ChemDiv1_004360 [O-][N+](=O)c1ccc2NC(=O)/C(=C/3\SC(=S)N(NC(=O)c4cccnc4)C3=O)/c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G05 compound treatment 351.9 162.0 0.85 342.8 155.0 0.81 1.1694 0.9997 1972415 ChemDiv1_004361 COc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G06 compound treatment 281.8 92.3 0.48 284.0 96.4 0.5 0.6947 0.9998 1972416 ChemDiv1_004362 [O-][N+](=O)c1ccccc1C(=O)NN2C(=O)/C(=C/c3ccc(Br)cc3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G07 compound treatment 285.6 96.0 0.5 287.4 99.8 0.52 0.7212 0.9998 1972417 ChemDiv1_004363 COc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G08 compound treatment 283.6 94.0 0.49 279.2 91.6 0.48 0.6836 0.9999 1972418 ChemDiv1_004364 Brc1ccc2NC(=O)/C(=C/3\SC(=S)N(NS(=O)(=O)c4ccccc4)C3=O)/c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G09 compound treatment 319.8 130.0 0.68 316.7 129.0 0.67 0.955 1.0 1972419 ChemDiv1_004365 CCOc1cc(cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)c1O)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G10 compound treatment 282.9 93.3 0.49 284.8 97.2 0.51 0.7016 0.9998 1972420 ChemDiv1_004366 [O-][N+](=O)c1ccccc1c2ccc(/C=C/3\NC(=S)N(C3=O)c4ccccc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G11 compound treatment 294.6 105.0 0.55 295.1 108.0 0.56 0.7827 1.0 1972421 ChemDiv1_004367 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G12 compound treatment 282.8 93.3 0.49 282.5 94.9 0.49 0.6928 1.0 1972422 ChemDiv1_004368 COc1cc(cc(OC)c1OC)C(=O)Oc2ccccc2/C=C/3\Sc4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G13 compound treatment 279.3 89.8 0.47 280.5 92.9 0.48 0.6726 0.9999 1972423 ChemDiv1_004369 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCCOc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G14 compound treatment 375.7 186.0 0.97 379.0 191.0 0.99 1.3902 0.9999 1972424 ChemDiv1_004370 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccccc3O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G15 compound treatment 292.1 103.0 0.53 291.8 104.0 0.54 0.7613 1.0 1972425 ChemDiv1_004371 CCOc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G16 compound treatment 376.2 187.0 0.97 388.1 201.0 1.04 1.4255 0.9994 1972426 ChemDiv1_004372 COc1ccccc1N(C=O)/C=C/2\Sc3ccccc3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G17 compound treatment 292.4 103.0 0.54 295.1 108.0 0.56 0.7746 0.9998 1972427 ChemDiv1_004373 CCOc1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G18 compound treatment 282.8 93.3 0.49 282.6 95.0 0.49 0.6932 1.0 1121995 ChemDiv1_004374 COc1ccccc1c2nc3sc4CCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G19 compound treatment 285.3 95.8 0.5 283.8 96.2 0.5 0.7068 1.0 1972428 ChemDiv1_004375 OC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G20 compound treatment 278.3 88.8 0.46 280.8 93.2 0.48 0.67 0.9997 1972429 ChemDiv1_004376 Cc1nc2scc(c3ccc(Br)cc3)c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G21 compound treatment 288.0 98.5 0.51 290.0 102.0 0.53 0.7396 0.9998 1924034 ChemDiv1_004377 COC(=O)CCN1C(=O)/C(=C/c2ccc(OCc3ccc(Cl)cc3)c(OC)c2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G22 compound treatment 278.4 88.8 0.46 275.9 88.3 0.46 0.6523 1.0 1972430 ChemDiv1_004378 Cc1cc2c(=O)oc(nc2s1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G23 mock treatment 283.4 93.8 0.49 278.6 91.0 0.47 0.6807 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 G24 mock treatment 75.1 -114.0 -0.6 77.4 -110.0 -0.57 -0.8272 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H01 compound treatment 281.9 92.3 0.48 287.4 99.8 0.52 0.7075 0.9993 1972431 ChemDiv1_004379 CCOC(=O)c1c(C)n(c2ccc(C)c(C)c2)c3ccc(OC(=O)c4ccccc4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H02 compound treatment 284.6 95.0 0.5 288.4 101.0 0.52 0.7212 0.9996 1948670 ChemDiv1_004380 CC1=NN(C(=O)C1/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H03 compound treatment 286.0 96.5 0.5 285.0 97.4 0.51 0.7138 1.0 1972432 ChemDiv1_004381 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)scc1c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H04 compound treatment 367.9 178.0 0.93 377.9 190.0 0.99 1.3574 0.9995 1689219 ChemDiv1_004382 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H05 compound treatment 282.4 92.8 0.48 285.1 97.5 0.51 0.7009 0.9997 1972433 ChemDiv1_004383 Cc1sc2[nH]c(=S)[nH]c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H06 compound treatment 286.5 97.0 0.51 296.9 109.0 0.57 0.7594 0.9983 1222639 ChemDiv1_004384 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H07 compound treatment 283.4 93.8 0.49 283.9 96.3 0.5 0.7002 0.9999 1191951 ChemDiv1_004385 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H08 compound treatment 287.2 97.7 0.51 293.9 106.0 0.55 0.751 0.9992 1465669 ChemDiv1_004386 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(cc4)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H09 compound treatment 283.0 93.5 0.49 284.8 97.2 0.51 0.702 0.9998 1685916 ChemDiv1_004387 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc(F)c5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H10 compound treatment 303.1 114.0 0.59 312.9 125.0 0.65 0.8794 0.9989 1565170 ChemDiv1_004388 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H11 compound treatment 284.7 95.2 0.5 282.3 94.7 0.49 0.6991 1.0 1358843 ChemDiv1_004389 CCN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H12 compound treatment 294.7 105.0 0.55 307.1 120.0 0.62 0.8271 0.9981 1195996 ChemDiv1_004390 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H13 compound treatment 277.2 87.7 0.46 281.3 93.7 0.49 0.6678 0.9995 1489629 ChemDiv1_004391 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H14 compound treatment 278.5 89.0 0.46 279.6 92.0 0.48 0.6663 0.9999 1972434 ChemDiv1_004392 O=C/1N(Cc2ccccc2)\C(=N/Cc3ccccc3)\S\C1=C/c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H15 compound treatment 278.7 89.2 0.47 285.2 97.6 0.51 0.6876 0.9991 1215521 ChemDiv1_004393 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5c(Cl)cccc5Cl)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H16 compound treatment 299.2 110.0 0.57 304.3 117.0 0.61 0.8334 0.9996 1972435 ChemDiv1_004394 CCOc1cc(C=c2sc3=NC(=C(C(c4c(OC)ccc5ccccc45)n3c2=O)C(=O)C)C)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H17 compound treatment 284.2 94.7 0.49 280.2 92.6 0.48 0.6895 0.9999 1478760 ChemDiv1_004395 Cc1cc(C)c2n(CC(O)CN3C(=O)c4ccccc4S3(=O)=O)c(c(c5ccccc5)c2c1)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H18 compound treatment 280.5 91.0 0.47 278.3 90.7 0.47 0.6689 1.0 1374726 ChemDiv1_004396 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccc(SC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H19 compound treatment 281.0 91.5 0.48 279.3 91.7 0.48 0.6744 1.0 1361970 ChemDiv1_004397 Clc1ccc(Cn2c(NC(=O)c3ccco3)nc4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H20 compound treatment 277.8 88.3 0.46 278.7 91.1 0.47 0.6604 0.9999 1972436 ChemDiv1_004398 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSCc2ccc(Cl)cc2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H21 compound treatment 280.5 91.0 0.47 276.2 88.6 0.46 0.6612 0.9999 1972437 ChemDiv1_004399 Cc1ccc(cc1)S(=O)(=O)Oc2ccccc2/C=C/3\N=C(OC3=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H22 compound treatment 277.9 88.3 0.46 278.3 90.7 0.47 0.6593 0.9999 1972438 ChemDiv1_004400 COc1ccc(N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccccc4[N+](=O)[O-])c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H23 mock treatment 286.1 96.5 0.5 280.0 92.4 0.48 0.6958 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 H24 mock treatment 88.8 -101.0 -0.53 80.0 -108.0 -0.56 -0.7671 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I01 compound treatment 280.4 90.8 0.47 288.8 101.0 0.53 0.7071 0.9986 1305861 ChemDiv1_004401 OC(=O)c1cc(Br)ccc1NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I02 compound treatment 298.3 109.0 0.57 297.7 110.0 0.57 0.8059 1.0 1972439 ChemDiv1_004402 CCOc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccc(Br)cc3)C2=O)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I03 compound treatment 310.2 121.0 0.63 300.0 112.0 0.58 0.8582 0.9993 1972440 ChemDiv1_004403 COc1cc(/C=C\2/SC(=S)N(C)C2=O)ccc1Oc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I04 compound treatment 282.8 93.3 0.49 283.0 95.4 0.5 0.6947 1.0 1972441 ChemDiv1_004404 CC(=O)N1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccc(O)cc3)C2=O)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I05 compound treatment 285.8 96.3 0.5 287.6 100.0 0.52 0.7226 0.9998 1972442 ChemDiv1_004405 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I06 compound treatment 284.1 94.5 0.49 280.6 93.0 0.48 0.6906 1.0 1972443 ChemDiv1_004406 Brc1ccc(CC2S/C(=N/c3ccccc3)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I07 compound treatment 285.6 96.0 0.5 284.2 96.6 0.5 0.7094 1.0 1972444 ChemDiv1_004407 COc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I08 compound treatment 281.1 91.5 0.48 282.3 94.7 0.49 0.6858 0.9999 1972445 ChemDiv1_004408 Oc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I09 compound treatment 294.6 105.0 0.55 295.5 108.0 0.56 0.7841 0.9999 1972446 ChemDiv1_004409 COc1ccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I10 compound treatment 334.0 144.0 0.75 337.7 150.0 0.78 1.0846 0.9998 1972447 ChemDiv1_004410 Clc1ccc(Cl)c(c1)c2ccc(/C=C/3\NC(=S)N(C3=O)c4ccccc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I11 compound treatment 281.3 91.8 0.48 284.2 96.6 0.5 0.6935 0.9997 1972448 ChemDiv1_004411 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I12 compound treatment 296.8 107.0 0.56 295.2 108.0 0.56 0.7911 1.0 1972449 ChemDiv1_004412 CC(=O)Oc1ccc(cc1/C=C/2\Sc3ccccc3C2=O)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I13 compound treatment 279.9 90.3 0.47 283.5 95.9 0.5 0.6858 0.9996 1972450 ChemDiv1_004413 [O-][N+](=O)c1ccc(Oc2cccc(/C=C\3/NC(=S)NC3=O)c2)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I14 compound treatment 310.7 121.0 0.63 313.8 126.0 0.66 0.9108 0.9998 1972451 ChemDiv1_004414 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc(Br)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I15 compound treatment 278.7 89.2 0.47 282.6 95.0 0.49 0.6781 0.9995 1972452 ChemDiv1_004415 [O-][N+](=O)c1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I16 compound treatment 321.3 132.0 0.69 319.5 132.0 0.69 0.9708 1.0 1972453 ChemDiv1_004416 O=CN(/C=C/1\Sc2ccccc2C1=O)c3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I17 compound treatment 284.5 95.0 0.5 286.2 98.6 0.51 0.7127 0.9999 1972454 ChemDiv1_004417 OC(=O)COc1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I18 compound treatment 284.4 94.8 0.49 284.9 97.3 0.51 0.7076 0.9999 1972455 ChemDiv1_004418 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I19 compound treatment 283.5 94.0 0.49 279.6 92.0 0.48 0.6847 0.9999 1474215 ChemDiv1_004419 C=CCn1c(SCC(=O)c2cccs2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I20 compound treatment 277.4 87.8 0.46 279.3 91.7 0.48 0.6611 0.9998 1972456 ChemDiv1_004420 Cc1sc2nc(C)oc(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I21 compound treatment 281.0 91.5 0.48 281.8 94.2 0.49 0.6836 0.9999 1268616 ChemDiv1_004421 Brc1ccccc1Oc2coc3cc(OC(=O)c4ccco4)ccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I22 compound treatment 278.4 88.8 0.46 278.9 91.3 0.47 0.6634 0.9999 1972457 ChemDiv1_004422 Cc1cc2c(=O)oc(nc2s1)c3ccc(cc3)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I23 mock treatment 279.0 89.5 0.47 279.5 91.9 0.48 0.6678 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 I24 mock treatment 80.5 -109.0 -0.57 76.9 -111.0 -0.58 -0.8091 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J01 compound treatment 288.2 98.7 0.51 287.1 99.5 0.52 0.7297 1.0 1725277 ChemDiv1_004423 CCOC(=O)c1c(C)n(c2ccccc2C)c3ccc(OC(=O)c4ccccc4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J02 compound treatment 299.0 109.0 0.57 298.6 111.0 0.58 0.8118 1.0 1972458 ChemDiv1_004424 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c(C)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J03 compound treatment 285.6 96.0 0.5 284.2 96.6 0.5 0.7094 1.0 1972459 ChemDiv1_004425 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)scc1c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J04 compound treatment 286.4 96.8 0.51 281.3 93.7 0.49 0.7017 0.9998 1404479 ChemDiv1_004426 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J05 compound treatment 283.1 93.5 0.49 283.6 96.0 0.5 0.698 0.9999 1972460 ChemDiv1_004427 CCOC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J06 compound treatment 287.5 98.0 0.51 287.1 99.5 0.52 0.7271 1.0 1266930 ChemDiv1_004428 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J07 compound treatment 282.9 93.3 0.49 281.2 93.6 0.49 0.6884 1.0 1590946 ChemDiv1_004429 Cn1c(=O)n(C)c2nc(NCc3ccco3)n(Cc4ccccc4Br)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J08 compound treatment 322.6 133.0 0.69 317.5 130.0 0.68 0.9683 0.9999 1200045 ChemDiv1_004430 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4ccc(cc4)C(=O)O)c(=O)n2C1c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J09 compound treatment 281.6 92.0 0.48 280.6 93.0 0.48 0.6814 1.0 1208663 ChemDiv1_004431 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(F)cc5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J10 compound treatment 280.5 91.0 0.47 281.7 94.1 0.49 0.6814 0.9999 1684224 ChemDiv1_004432 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J11 compound treatment 280.1 90.5 0.47 282.3 94.7 0.49 0.6821 0.9998 1359181 ChemDiv1_004433 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J12 compound treatment 285.6 96.0 0.5 283.6 96.0 0.5 0.7072 1.0 1658381 ChemDiv1_004434 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J13 compound treatment 279.4 89.8 0.47 281.7 94.1 0.49 0.6773 0.9998 1227802 ChemDiv1_004435 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(Cc4ccc(Cl)cc4Cl)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J14 compound treatment 286.1 96.5 0.5 283.9 96.3 0.5 0.7101 1.0 1200293 ChemDiv1_004436 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5cc(Br)c(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J15 compound treatment 281.4 91.8 0.48 279.1 91.5 0.48 0.6752 1.0 1186646 ChemDiv1_004437 Cn1c(=O)n(C)c2nc(NCCc3ccccc3)n(Cc4c(F)cccc4Cl)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J16 compound treatment 280.6 91.0 0.47 285.1 97.5 0.51 0.6943 0.9995 1972461 ChemDiv1_004438 COc1ccc(C=c2sc3=NC(=C(C(c4c(OC)ccc5ccccc45)n3c2=O)C(=O)C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J17 compound treatment 277.6 88.0 0.46 283.0 95.4 0.5 0.6755 0.9993 1611579 ChemDiv1_004439 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(O)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J18 compound treatment 280.0 90.5 0.47 280.9 93.3 0.49 0.6766 0.9999 1568461 ChemDiv1_004440 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(SC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J19 compound treatment 281.9 92.3 0.48 274.8 87.2 0.45 0.6612 0.9995 1972462 ChemDiv1_004441 CCOC(=O)CSc1nc2cc(C)ccc2[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J20 compound treatment 280.8 91.3 0.48 279.9 92.3 0.48 0.6759 1.0 1972463 ChemDiv1_004442 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSCc2cccc(Cl)c2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J21 compound treatment 287.4 97.8 0.51 283.9 96.3 0.5 0.7149 1.0 1972464 ChemDiv1_004443 Clc1ccc(cc1)N2C(=O)/C(=C/c3cc4OCOc4cc3Br)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J22 compound treatment 279.4 89.8 0.47 279.1 91.5 0.48 0.6678 1.0 1783361 ChemDiv1_004444 COc1ccc(N(CC(=O)NCc2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J23 mock treatment 282.3 92.8 0.48 278.6 91.0 0.47 0.6766 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 J24 mock treatment 82.8 -107.0 -0.56 79.4 -108.0 -0.56 -0.7914 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K01 compound treatment 283.1 93.5 0.49 282.6 95.0 0.49 0.6943 1.0 1972465 ChemDiv1_004445 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K02 compound treatment 283.0 93.5 0.49 283.3 95.7 0.5 0.6965 0.9999 1972466 ChemDiv1_004446 COC(=O)c1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccc(Br)cc3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K03 compound treatment 286.3 96.8 0.5 281.0 93.4 0.49 0.7002 0.9998 1944052 ChemDiv1_004447 Fc1ccc(COc2ccc(Br)cc2/C=C\3/SC(=O)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K04 compound treatment 285.0 95.5 0.5 283.7 96.1 0.5 0.7054 1.0 1927063 ChemDiv1_004448 COc1ccc(/C=C\2/SC(=NC2=O)N3CCN(CC3)C(=O)CN4C(=O)S\C(=C/c5ccccc5F)\C4=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K05 compound treatment 281.0 91.5 0.48 282.8 95.2 0.49 0.6873 0.9998 1972467 ChemDiv1_004449 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K06 compound treatment 279.8 90.3 0.47 282.2 94.6 0.49 0.6807 0.9998 1972468 ChemDiv1_004450 Cc1ccccc1CC2S/C(=N/c3ccc(Br)cc3)/NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K07 compound treatment 286.1 96.5 0.5 291.2 104.0 0.54 0.737 0.9994 1972469 ChemDiv1_004451 CCOc1cc(/C=C\2/SC(=O)N(C2=O)c3ccc(Cl)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K08 compound treatment 281.5 92.0 0.48 284.5 96.9 0.5 0.6954 0.9997 1972470 ChemDiv1_004452 CN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(Cl)cc4)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K09 compound treatment 447.1 258.0 1.34 444.2 257.0 1.33 1.8932 1.0 1972471 ChemDiv1_004453 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(Br)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K10 compound treatment 288.4 98.8 0.52 282.8 95.2 0.49 0.7146 0.9998 1972472 ChemDiv1_004454 COC(=O)C1=C(C)N=c2sc(=Cc3cccc(c3)[N+](=O)[O-])c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K11 compound treatment 311.5 122.0 0.64 315.2 128.0 0.66 0.9189 0.9998 1972473 ChemDiv1_004455 CCOc1ccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K12 compound treatment 287.8 98.3 0.51 292.9 105.0 0.55 0.7495 0.9995 1972474 ChemDiv1_004456 [O-][N+](=O)c1ccc(o1)C(=O)Oc2ccccc2/C=C/3\Sc4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K13 compound treatment 280.0 90.5 0.47 283.5 95.9 0.5 0.6862 0.9996 1447438 ChemDiv1_004457 COc1cc(C=O)ccc1Oc2nc(nc(n2)N3CCCCC3)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K14 compound treatment 285.8 96.3 0.5 287.3 99.7 0.52 0.7215 0.9999 1972475 ChemDiv1_004458 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K15 compound treatment 281.1 91.5 0.48 282.0 94.4 0.49 0.6847 0.9999 1972476 ChemDiv1_004459 [O-][N+](=O)c1ccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K16 compound treatment 358.2 169.0 0.88 350.1 163.0 0.84 1.2194 0.9998 1972477 ChemDiv1_004460 CC(=O)N(/C=C/1\Sc2ccccc2C1=O)c3ccc(cc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K17 compound treatment 287.1 97.5 0.51 290.7 103.0 0.54 0.7388 0.9997 1972478 ChemDiv1_004461 CCOc1ccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K18 compound treatment 279.5 90.0 0.47 280.8 93.2 0.48 0.6744 0.9999 1972479 ChemDiv1_004462 Clc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K19 compound treatment 282.7 93.2 0.49 280.8 93.2 0.48 0.6862 1.0 1972480 ChemDiv1_004463 COc1ccc(cc1OC)c2nc3sc4CCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K20 compound treatment 279.6 90.0 0.47 274.9 87.3 0.45 0.6531 0.9999 1647504 ChemDiv1_004464 CCc1nc2sc3CCCCc3c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K21 compound treatment 279.0 89.5 0.47 281.0 93.4 0.49 0.6733 0.9998 1972481 ChemDiv1_004465 COc1ccccc1c2c(oc3c(CN4CCCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K22 compound treatment 280.1 90.5 0.47 279.1 91.5 0.48 0.6704 1.0 1505504 ChemDiv1_004466 Cc1ccc(cc1)c2csc3nc(Cc4ccccc4)oc(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K23 mock treatment 283.9 94.3 0.49 279.0 91.4 0.48 0.684 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 K24 mock treatment 78.8 -111.0 -0.58 72.4 -115.0 -0.6 -0.8319 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L01 compound treatment 287.5 98.0 0.51 283.6 96.0 0.5 0.7142 0.9999 1334632 ChemDiv1_004467 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3ccc(OC(=O)C#Cc4ccccc4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L02 compound treatment 300.1 111.0 0.58 291.8 104.0 0.54 0.7908 0.9995 1948497 ChemDiv1_004468 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L03 compound treatment 282.7 93.2 0.49 287.4 99.8 0.52 0.7105 0.9995 1972482 ChemDiv1_004469 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccc(C)cc3)C)scc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L04 compound treatment 283.6 94.0 0.49 274.8 87.2 0.45 0.6675 0.9992 1670085 ChemDiv1_004470 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(CC=C)c4ccccc34)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L05 compound treatment 283.9 94.3 0.49 275.1 87.5 0.45 0.6697 0.9992 1972483 ChemDiv1_004471 NNC(=O)CSc1nc2scc(c3ccccc3)c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L06 compound treatment 285.8 96.3 0.5 280.5 92.9 0.48 0.6965 0.9998 1130488 ChemDiv1_004472 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3OC)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L07 compound treatment 279.2 89.7 0.47 285.3 97.7 0.51 0.6898 0.9991 1343629 ChemDiv1_004473 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4cccc(Br)c4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L08 compound treatment 280.9 91.3 0.48 278.7 91.1 0.47 0.6719 1.0 1725771 ChemDiv1_004474 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(OC)cc3OC)c(=O)n2C1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L09 compound treatment 284.6 95.0 0.5 282.8 95.2 0.49 0.7006 1.0 1463143 ChemDiv1_004475 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(Cc4ccccc4Br)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L10 compound treatment 333.9 144.0 0.75 345.9 158.0 0.82 1.1144 0.999 1524465 ChemDiv1_004476 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N(C)C)c(=O)n2C1c4c(OC)ccc5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L11 compound treatment 281.9 92.3 0.48 284.5 96.9 0.5 0.6969 0.9998 1714209 ChemDiv1_004477 Cn1c(=O)n(C)c2nc(NCc3ccco3)n(Cc4ccc(Br)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L12 compound treatment 253.6 64.0 0.33 246.9 59.3 0.31 0.4543 0.9992 1704027 ChemDiv1_004478 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(CC=C)c4ccccc34)c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L13 compound treatment 283.3 93.8 0.49 286.6 99.0 0.51 0.7097 0.9997 1188386 ChemDiv1_004479 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(Cl)cc5Cl)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L14 compound treatment 395.3 206.0 1.07 385.9 198.0 1.03 1.4879 0.9998 1931218 ChemDiv1_004480 CCN(CC)c1ccc(C=c2sc3=NC(=C(C(c4ccc(OC)cc4OC)n3c2=O)C(=O)C)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L15 compound treatment 281.6 92.0 0.48 275.8 88.2 0.46 0.6638 0.9997 1508793 ChemDiv1_004481 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc6ccccc56)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L16 compound treatment 354.9 165.0 0.86 362.0 174.0 0.91 1.251 0.9997 1972484 ChemDiv1_004482 COc1ccc2ccccc2c1C3C(=C(C)N=c4sc(=Cc5ccc(cc5)N(C)C)c(=O)n34)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L17 compound treatment 279.7 90.2 0.47 283.9 96.3 0.5 0.6865 0.9995 1972485 ChemDiv1_004483 CC(=O)Nc1nc2ccccc2n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L18 compound treatment 282.5 93.0 0.48 281.1 93.5 0.49 0.6866 1.0 1972486 ChemDiv1_004484 CCOc1ccc(cc1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccc(SC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L19 compound treatment 281.1 91.5 0.48 281.6 94.0 0.49 0.6832 0.9999 1972487 ChemDiv1_004485 Brc1ccc(cc1)c2nc3sc4CCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L20 compound treatment 278.6 89.0 0.46 281.0 93.4 0.49 0.6718 0.9998 1972488 ChemDiv1_004486 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSCc2ccccc2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L21 compound treatment 284.0 94.5 0.49 276.3 88.7 0.46 0.6745 0.9995 1972489 ChemDiv1_004487 COc1cc(OC)c(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L22 compound treatment 274.6 85.0 0.44 274.7 87.1 0.45 0.6339 0.9999 1783360 ChemDiv1_004488 COc1ccc(N(CC(=O)NCc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L23 mock treatment 278.6 89.0 0.46 281.4 93.8 0.49 0.6733 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 L24 mock treatment 77.5 -112.0 -0.58 80.8 -107.0 -0.56 -0.8058 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M01 compound treatment 286.1 96.5 0.5 285.0 97.4 0.51 0.7142 1.0 1972490 ChemDiv1_004489 OC(=O)c1ccc(NC(=O)CCN2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M02 compound treatment 288.8 99.3 0.52 280.3 92.7 0.48 0.7069 0.9994 1972491 ChemDiv1_004490 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(NC(=O)c4ccccc4[N+](=O)[O-])C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M03 compound treatment 284.6 95.0 0.5 279.2 91.6 0.48 0.6873 0.9998 1972492 ChemDiv1_004491 CCOc1cc(/C=C\2/SC(=O)NC2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M04 compound treatment 282.9 93.3 0.49 287.8 100.0 0.52 0.7127 0.9994 1972493 ChemDiv1_004492 Cc1cccc(/N=C/2\NC(=O)\C(=C/3\C(=O)Nc4ccc(Br)cc34)\S2)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M05 compound treatment 280.7 91.2 0.48 281.3 93.7 0.49 0.6807 0.9999 1972494 ChemDiv1_004493 CN1C(=O)N(C)C(=O)C(=Cc2cc(Br)ccc2OCc3ccccc3)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M06 compound treatment 281.6 92.0 0.48 284.5 96.9 0.5 0.6958 0.9997 1972495 ChemDiv1_004494 Clc1ccc(CC2S/C(=N/c3ccc(Cl)cc3)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M07 compound treatment 283.7 94.2 0.49 283.8 96.2 0.5 0.7009 1.0 1972496 ChemDiv1_004495 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OS(=O)(=O)c3ccccc3)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M08 compound treatment 278.3 88.8 0.46 279.1 91.5 0.48 0.6637 0.9999 1972497 ChemDiv1_004496 Oc1ccc2c(=O)c(c3ccccc3Cl)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M09 compound treatment 328.3 139.0 0.72 327.8 140.0 0.73 1.0272 1.0 1972498 ChemDiv1_004497 Oc1ccc(Br)cc1/C=C\2/S/C(=N/c3ccccc3)/NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M10 compound treatment 284.4 94.8 0.49 282.5 94.9 0.49 0.6987 1.0 1972499 ChemDiv1_004498 [O-][N+](=O)c1cccc(N/C=C\2/Sc3ccccc3C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M11 compound treatment 289.9 100.0 0.52 288.3 101.0 0.52 0.7403 1.0 1972500 ChemDiv1_004499 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M12 compound treatment 278.3 88.8 0.46 279.3 91.7 0.48 0.6645 0.9999 1972501 ChemDiv1_004500 C/C(=C/1\Sc2ccccc2C1=O)/NC3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M13 compound treatment 280.7 91.2 0.48 281.6 94.0 0.49 0.6818 0.9999 1511652 ChemDiv1_004501 COc1cc(C=O)ccc1Oc2nc(nc(n2)N3CCOCC3)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M14 compound treatment 358.5 169.0 0.88 357.3 170.0 0.88 1.247 1.0 1972502 ChemDiv1_004502 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc(O)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M15 compound treatment 281.2 91.7 0.48 285.1 97.5 0.51 0.6965 0.9996 1972503 ChemDiv1_004503 COc1cc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M16 compound treatment 282.5 93.0 0.48 279.3 91.7 0.48 0.68 1.0 1972504 ChemDiv1_004504 CN(/C=C/1\Sc2ccccc2C1=O)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M17 compound treatment 289.0 99.5 0.52 287.2 99.6 0.52 0.733 1.0 1972505 ChemDiv1_004505 Brc1ccc(OCc2cccc3ccccc23)c(/C=C\4/NC(=S)NC4=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M18 compound treatment 280.1 90.5 0.47 278.9 91.3 0.47 0.6696 1.0 1972506 ChemDiv1_004506 Brc1cccc(c1)c2nc3scc(c4ccccc4)c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M19 compound treatment 279.8 90.3 0.47 281.0 93.4 0.49 0.6762 0.9999 1972507 ChemDiv1_004507 Fc1ccc(cc1)c2csc3nc(SCC(=O)Nc4ccc5OCOc5c4)n(CC=C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M20 compound treatment 280.2 90.7 0.47 277.8 90.2 0.47 0.666 1.0 1972508 ChemDiv1_004508 CCc1nc2scc(c3ccc(Br)cc3)c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M21 compound treatment 278.8 89.3 0.47 282.0 94.4 0.49 0.6762 0.9997 1972509 ChemDiv1_004509 COc1ccccc1c2c(oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M22 compound treatment 298.2 109.0 0.57 283.4 95.8 0.5 0.7529 0.9979 1972510 ChemDiv1_004510 O=c1oc(CCCCc2nc3sc4CCCCc4c3c(=O)o2)nc5sc6CCCCc6c15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M23 mock treatment 280.8 91.3 0.48 277.2 89.6 0.47 0.666 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 M24 mock treatment 198.8 9.25 0.05 189.2 1.61 0.01 0.04 0.8177 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N01 compound treatment 285.3 95.8 0.5 283.5 95.9 0.5 0.7057 1.0 1458021 ChemDiv1_004511 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N02 compound treatment 286.0 96.5 0.5 286.4 98.8 0.51 0.719 0.9999 1972511 ChemDiv1_004512 COc1cc(ccc1c2ccc(/C=C/3\C(=O)NC(=S)N(C3=O)c4ccccc4)o2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N03 compound treatment 282.8 93.3 0.49 283.9 96.3 0.5 0.698 0.9999 1972512 ChemDiv1_004513 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccc(C)cc3)C)sc(C)c1c4ccc5cc(OC)ccc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N04 compound treatment 284.7 95.2 0.5 284.4 96.8 0.5 0.7068 1.0 1447307 ChemDiv1_004514 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(cc3)C(=O)OC)c(=O)n2C1c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N05 compound treatment 280.9 91.3 0.48 280.2 92.6 0.48 0.6774 1.0 1972513 ChemDiv1_004515 CC/1=NN(C(=O)\C1=C/Nc2cc(cc(c2O)C(C)(C)C)C(C)(C)C)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N06 compound treatment 284.2 94.7 0.49 287.0 99.4 0.52 0.7145 0.9997 1972514 ChemDiv1_004516 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N07 compound treatment 279.0 89.5 0.47 282.3 94.7 0.49 0.6781 0.9996 1510773 ChemDiv1_004517 CC1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N08 compound treatment 456.3 267.0 1.39 445.5 258.0 1.34 1.9319 0.9998 1286217 ChemDiv1_004518 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N09 compound treatment 283.4 93.8 0.49 284.2 96.6 0.5 0.7013 0.9999 1457126 ChemDiv1_004519 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccccc5Br)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N10 compound treatment 369.9 180.0 0.94 369.6 182.0 0.95 1.3343 1.0 1570438 ChemDiv1_004520 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N(C)C)c(=O)n2C1c4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N11 compound treatment 281.2 91.7 0.48 280.4 92.8 0.48 0.6792 1.0 1469965 ChemDiv1_004521 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(Cc4ccc(Br)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N12 compound treatment 280.6 91.0 0.47 281.6 94.0 0.49 0.6814 0.9999 1702217 ChemDiv1_004522 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3OC)c(=O)n2C1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N13 compound treatment 282.0 92.5 0.48 282.7 95.1 0.49 0.6906 0.9999 1972515 ChemDiv1_004523 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccc(Cl)c(Cl)c3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N14 compound treatment 320.3 131.0 0.68 320.2 133.0 0.69 0.9697 1.0 1972516 ChemDiv1_004524 COc1ccc(C2C(=C(C)N=c3sc(=Cc4cc(C)n(c4C)c5ccccc5)c(=O)n23)C(=O)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N15 compound treatment 277.9 88.3 0.46 278.3 90.7 0.47 0.6593 0.9999 1218930 ChemDiv1_004525 CCn1c2ccccc2c3nc4cc(OC)c(OC)cc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N16 compound treatment 282.6 93.0 0.49 282.3 94.7 0.49 0.6914 1.0 1972517 ChemDiv1_004526 COc1ccc(C=c2sc3=NC(=C(C(c4c(OC)ccc5ccccc45)n3c2=O)C(=O)C)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N17 compound treatment 278.1 88.5 0.46 279.1 91.5 0.48 0.663 0.9999 1232486 ChemDiv1_004527 CC(=O)Nc1nc2ccccc2n1Cc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N18 compound treatment 279.4 89.8 0.47 277.2 89.6 0.47 0.6608 1.0 1972518 ChemDiv1_004528 CCOc1ccc(cc1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(SC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N19 compound treatment 282.2 92.7 0.48 277.0 89.4 0.46 0.6704 0.9998 1701332 ChemDiv1_004529 Clc1ccc(OCc2nc3ccccc3c(=O)n2c4ccc(Br)cn4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N20 compound treatment 261.2 71.7 0.37 284.0 96.4 0.5 0.6187 0.9896 1972519 ChemDiv1_004530 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2cccc(c2)C(F)(F)F)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N21 compound treatment 281.1 91.5 0.48 281.2 93.6 0.49 0.6818 1.0 1972520 ChemDiv1_004531 CCOc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(OCC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N22 compound treatment 276.6 87.0 0.45 276.9 89.3 0.46 0.6494 0.9999 1972521 ChemDiv1_004532 COc1ccc(Cl)cc1N(CC(=O)NCc2ccccn2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N23 mock treatment 282.6 93.0 0.49 281.7 94.1 0.49 0.6891 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 N24 mock treatment 197.4 7.85 0.04 194.8 7.21 0.04 0.0555 0.999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O01 compound treatment 283.2 93.7 0.49 290.0 102.0 0.53 0.7219 0.9991 1201459 ChemDiv1_004533 OC(=O)c1cc(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)cc(c1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O02 compound treatment 282.7 93.2 0.49 279.9 92.3 0.48 0.6829 1.0 1942909 ChemDiv1_004534 CCOc1ccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O03 compound treatment 286.9 97.3 0.51 283.8 96.2 0.5 0.7127 1.0 1972522 ChemDiv1_004535 Oc1c(Br)cc(/C=C\2/SC(=S)N(C2=O)c3ccc(cc3)[N+](=O)[O-])cc1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O04 compound treatment 283.2 93.7 0.49 283.3 95.7 0.5 0.6972 1.0 1972523 ChemDiv1_004536 Cc1ccc(/N=C/2\NC(=O)\C(=C/3\C(=O)Nc4ccc(Br)cc34)\S2)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O05 compound treatment 281.2 91.7 0.48 279.8 92.2 0.48 0.677 1.0 1972524 ChemDiv1_004537 Clc1ccc(COc2ccccc2/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O06 compound treatment 279.0 89.5 0.47 279.7 92.1 0.48 0.6685 0.9999 1972525 ChemDiv1_004538 Brc1ccc(CC2S/C(=N/c3ccccn3)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O07 compound treatment 310.3 121.0 0.63 308.4 121.0 0.63 0.8895 1.0 1972526 ChemDiv1_004539 CCOc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O08 compound treatment 281.9 92.3 0.48 283.4 95.8 0.5 0.6928 0.9999 1972527 ChemDiv1_004540 CN1CCN(Cc2c(O)ccc3c(=O)c(c4ccccc4Cl)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O09 compound treatment 401.9 212.0 1.11 406.2 219.0 1.14 1.5868 0.9999 1972528 ChemDiv1_004541 Oc1c(Cl)cc(Br)cc1/C=C\2/S/C(=N/c3ccccc3)/NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O10 compound treatment 320.9 131.0 0.69 306.4 119.0 0.62 0.9212 0.9987 1972529 ChemDiv1_004542 O=C1/C(=C\Nc2cccnc2)/Sc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O11 compound treatment 289.7 100.0 0.52 286.3 98.7 0.51 0.7322 1.0 1972530 ChemDiv1_004543 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O12 compound treatment 347.3 158.0 0.82 335.5 148.0 0.77 1.1256 0.9994 1972531 ChemDiv1_004544 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O13 compound treatment 282.7 93.2 0.49 281.9 94.3 0.49 0.6903 1.0 1972532 ChemDiv1_004545 COc1cc(/C=C\2/NC(=S)NC2=O)cc(Br)c1OC(=O)C3(CC4CC5CC(C4)C3)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O14 compound treatment 298.0 108.0 0.57 298.6 111.0 0.58 0.8081 1.0 1972533 ChemDiv1_004546 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O15 compound treatment 283.7 94.2 0.49 284.1 96.5 0.5 0.702 0.9999 1972534 ChemDiv1_004547 COc1ccccc1/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O16 compound treatment 376.5 187.0 0.98 363.7 176.0 0.92 1.3369 0.9995 1972535 ChemDiv1_004548 COc1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O17 compound treatment 279.3 89.8 0.47 276.9 89.3 0.46 0.6593 1.0 1972536 ChemDiv1_004549 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OS(=O)(=O)c3ccccc3[N+](=O)[O-])C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O18 compound treatment 278.5 89.0 0.46 278.4 90.8 0.47 0.6619 1.0 1972537 ChemDiv1_004550 Cc1ccc(cc1)c2csc3nc(oc(=O)c23)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O19 compound treatment 282.9 93.3 0.49 280.1 92.5 0.48 0.6844 1.0 1522963 ChemDiv1_004551 c1ccc(cc1)c2nnc(n3nnc4ccccc34)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O20 compound treatment 278.4 88.8 0.46 274.5 86.9 0.45 0.6472 0.9999 1472035 ChemDiv1_004552 CCc1nc2scc(c3cccs3)c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O21 compound treatment 282.7 93.2 0.49 281.2 93.6 0.49 0.6877 1.0 1923861 ChemDiv1_004553 COc1ccccc1c2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O22 compound treatment 278.6 89.0 0.46 275.1 87.5 0.45 0.6501 0.9999 1463297 ChemDiv1_004554 CCOC(=O)c1c(C)n(c2ccc(I)cc2)c3ccc(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O23 mock treatment 284.8 95.3 0.5 281.4 93.8 0.49 0.6962 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 O24 mock treatment 97.9 -91.7 -0.48 103.1 -84.5 -0.44 -0.6486 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P01 compound treatment 283.7 94.2 0.49 286.5 98.9 0.51 0.7108 0.9997 1972538 ChemDiv1_004555 CCOC(=O)c1c(N/C=C/2\N=C(OC2=O)c3ccccc3)scc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P02 compound treatment 296.2 107.0 0.56 289.6 102.0 0.53 0.7684 0.9997 1972539 ChemDiv1_004556 COc1cc(/C=C/2\Sc3ccccc3C2=O)c(Br)cc1OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P03 compound treatment 284.7 95.2 0.5 281.6 94.0 0.49 0.6965 1.0 1444873 ChemDiv1_004557 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)scc1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P04 compound treatment 285.3 95.8 0.5 283.2 95.6 0.5 0.7046 1.0 1249662 ChemDiv1_004558 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(SC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P05 compound treatment 279.8 90.3 0.47 287.9 100.0 0.52 0.7016 0.9987 1218907 ChemDiv1_004559 Cn1c(=O)n(C)c2nc(N3CCN(Cc4ccccc4)CC3)n(Cc5cccc(Cl)c5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P06 compound treatment 285.9 96.3 0.5 283.1 95.5 0.5 0.7065 1.0 1565872 ChemDiv1_004560 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(SC)cc3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P07 compound treatment 287.2 97.7 0.51 280.9 93.3 0.49 0.7032 0.9997 1548199 ChemDiv1_004561 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc(Cl)c5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P08 compound treatment 306.6 117.0 0.61 305.3 118.0 0.61 0.8644 1.0 1614452 ChemDiv1_004562 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P09 compound treatment 280.3 90.8 0.47 279.9 92.3 0.48 0.674 1.0 1690412 ChemDiv1_004563 COc1ccc(CCNc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Br)c4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P10 compound treatment 281.0 91.5 0.48 283.6 96.0 0.5 0.6902 0.9997 1204469 ChemDiv1_004564 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(SC)cc3)c(=O)n2C1c4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P11 compound treatment 280.3 90.8 0.47 278.7 91.1 0.47 0.6696 1.0 1643100 ChemDiv1_004565 Cn1c(=O)n(C)c2nc(NCCc3ccccc3)n(Cc4ccc(Br)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P12 compound treatment 281.6 92.0 0.48 282.5 94.9 0.49 0.6884 0.9999 1325001 ChemDiv1_004566 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(CC=C)c4ccccc34)c(=O)n2C1c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P13 compound treatment 280.1 90.5 0.47 282.8 95.2 0.49 0.684 0.9997 1339246 ChemDiv1_004567 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P14 compound treatment 365.2 176.0 0.92 371.0 183.0 0.95 1.3221 0.9998 1209999 ChemDiv1_004568 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OCC)c3)c(=O)n2C1c4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P15 compound treatment 274.2 84.7 0.44 278.5 90.9 0.47 0.6464 0.9994 1648069 ChemDiv1_004569 COc1cc2nc3n(C(C)C)c4ccccc4c3nc2cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P16 compound treatment 280.2 90.7 0.47 279.9 92.3 0.48 0.6737 1.0 1972540 ChemDiv1_004570 COc1ccccc1C2C(=C(C)N=c3sc(=Cc4cc(OC)c(OC)c(OC)c4)c(=O)n23)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P17 compound treatment 281.8 92.3 0.48 282.7 95.1 0.49 0.6899 0.9999 1409228 ChemDiv1_004571 CC(=O)Nc1nc2ccccc2n1Cc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P18 compound treatment 279.1 89.5 0.47 281.0 93.4 0.49 0.6737 0.9998 1204228 ChemDiv1_004572 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P19 compound treatment 278.5 89.0 0.46 283.2 95.6 0.5 0.6795 0.9994 1938153 ChemDiv1_004573 CC1CCc2c(C1)sc3nc(oc(=O)c23)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P20 compound treatment 279.8 90.3 0.47 279.7 92.1 0.48 0.6715 1.0 1972541 ChemDiv1_004574 [O-][N+](=O)c1cccc(c1)N(CC(=O)NCCSCc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P21 compound treatment 274.5 85.0 0.44 273.7 86.1 0.45 0.6299 1.0 1972542 ChemDiv1_004575 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(cc1OC)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P22 compound treatment 281.8 92.3 0.48 280.0 92.4 0.48 0.6799 1.0 1949649 ChemDiv1_004576 COc1ccc(Cl)cc1N(CC(=O)N2CCC(C)CC2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P23 mock treatment 280.5 91.0 0.47 278.3 90.7 0.47 0.6689 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.599 P24 mock treatment 101.0 -88.5 -0.46 93.0 -94.6 -0.49 -0.6743 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A01 compound treatment 285.9 96.4 0.5 287.2 101.0 0.52 0.7254 0.9998 1951696 ChemDiv1_004577 COc1ccc(Cl)cc1N(CC(=O)NCCCC(C)(C)C2OCCO2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A02 compound treatment 282.9 93.4 0.49 286.5 99.9 0.52 0.7117 0.9995 1972543 ChemDiv1_004578 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(Br)c(OC)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A03 compound treatment 281.0 91.5 0.48 286.1 99.5 0.52 0.7032 0.9992 1972544 ChemDiv1_004579 C1C2CC3CC1CC(C2)C3Nc4nc5nonc5nc4NC6C7CC8CC(C7)CC6C8 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A04 compound treatment 280.1 90.6 0.47 282.4 95.8 0.5 0.6863 0.9997 1972545 ChemDiv1_004580 O=C1N(CSc2nnc(o2)c3ccco3)c4ccccc4C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A05 compound treatment 285.3 95.8 0.5 279.9 93.3 0.48 0.6963 0.9999 1168209 ChemDiv1_004581 COc1cc(C=c2sc3nc4c(C)c(C)ccc4n3c2=O)ccc1OC(C)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A06 compound treatment 281.3 91.8 0.48 278.6 92.0 0.48 0.6768 1.0 1972546 ChemDiv1_004582 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\c3cccnc3)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A07 compound treatment 282.0 92.5 0.48 283.2 96.6 0.5 0.6963 0.9998 1972547 ChemDiv1_004583 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(cc4C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A08 compound treatment 280.2 90.7 0.47 284.2 97.6 0.51 0.6933 0.9994 1972548 ChemDiv1_004584 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A09 compound treatment 280.4 90.9 0.47 281.7 95.1 0.49 0.6849 0.9998 1972549 ChemDiv1_004585 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A10 compound treatment 283.1 93.6 0.49 286.7 100.0 0.52 0.7132 0.9995 1972550 ChemDiv1_004586 Fc1cccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A11 compound treatment 280.6 91.1 0.48 280.2 93.6 0.49 0.6801 0.9999 1972551 ChemDiv1_004587 Fc1ccc(cc1)c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A12 compound treatment 275.6 86.1 0.45 276.4 89.8 0.47 0.6477 0.9998 1972552 ChemDiv1_004588 OC(=O)CN1C(=O)/C(=C/2\SC(=NC2=O)Nc3cccc(Cl)c3Cl)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A13 compound treatment 279.2 89.7 0.47 280.4 93.8 0.49 0.6757 0.9998 1972553 ChemDiv1_004589 COC(=O)c1ccc(NC(=O)CSc2nnc(C)c3ccccc23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A14 compound treatment 281.2 91.7 0.48 281.0 94.4 0.49 0.6852 0.9999 1972554 ChemDiv1_004590 COc1ccc(NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A15 compound treatment 278.5 89.0 0.46 280.6 94.0 0.49 0.6738 0.9997 1595733 ChemDiv1_004591 Cc1nn(CC(=O)Nc2ccc(cc2)S(=O)(=O)N)c(=O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A16 compound treatment 279.8 90.3 0.47 280.4 93.8 0.49 0.6779 0.9999 1972555 ChemDiv1_004592 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)N6CCCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A17 compound treatment 274.9 85.4 0.45 274.5 87.9 0.46 0.6381 0.9999 1570540 ChemDiv1_004593 COc1nnc(c2ccc(C)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A18 compound treatment 274.5 85.0 0.44 277.5 90.9 0.47 0.6477 0.9995 1972556 ChemDiv1_004594 CCOC(=O)CSc1nnc(CCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A19 compound treatment 278.3 88.8 0.46 276.8 90.2 0.47 0.6591 1.0 1972557 ChemDiv1_004595 COc1cc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)ccc1OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A20 compound treatment 276.5 87.0 0.45 277.6 91.0 0.47 0.6554 0.9998 1972558 ChemDiv1_004596 Cc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A21 compound treatment 278.3 88.8 0.46 280.8 94.2 0.49 0.6738 0.9996 1946655 ChemDiv1_004597 COc1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A22 compound treatment 274.9 85.4 0.45 274.2 87.6 0.46 0.637 0.9999 1972559 ChemDiv1_004598 Cc1onc(c1C(=O)Nc2nnc(s2)c3cccc(c3)[N+](=O)[O-])c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A23 mock treatment 280.1 90.6 0.47 279.0 92.4 0.48 0.6738 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 A24 mock treatment 85.1 -104.0 -0.54 75.9 -111.0 -0.58 -0.792 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B01 compound treatment 286.1 96.6 0.5 285.3 98.7 0.51 0.7191 1.0 1972560 ChemDiv1_004599 CCC(=O)N1N=C(CC1c2ccccc2OC)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B02 compound treatment 283.0 93.5 0.49 284.7 98.1 0.51 0.7055 0.9998 1940813 ChemDiv1_004600 OCCCNC(=O)CCCSc1nc2sc3CCCCc3c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B03 compound treatment 285.0 95.5 0.5 288.8 102.0 0.53 0.7279 0.9995 1303907 ChemDiv1_004601 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B04 compound treatment 283.9 94.4 0.49 279.7 93.1 0.48 0.6904 1.0 1527431 ChemDiv1_004602 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc(cs3)c4cc5ccccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B05 compound treatment 282.9 93.4 0.49 280.8 94.2 0.49 0.6908 1.0 1466106 ChemDiv1_004603 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B06 compound treatment 281.6 92.1 0.48 278.6 92.0 0.48 0.6779 1.0 1972561 ChemDiv1_004604 O=C(CN1C(=O)c2ccccc2C1=O)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B07 compound treatment 278.9 89.4 0.47 278.0 91.4 0.48 0.6657 1.0 1972562 ChemDiv1_004605 [O-][N+](=O)c1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B08 compound treatment 284.6 95.1 0.5 284.6 98.0 0.51 0.711 0.9999 1634578 ChemDiv1_004606 COc1ccc(cc1)c2csc3[nH]c(=S)n(CC=C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B09 compound treatment 283.5 94.0 0.49 283.2 96.6 0.5 0.7018 0.9999 1972563 ChemDiv1_004607 CCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OCC)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B10 compound treatment 274.4 84.9 0.44 279.0 92.4 0.48 0.6528 0.9992 1606278 ChemDiv1_004608 OCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B11 compound treatment 280.9 91.4 0.48 284.4 97.8 0.51 0.6966 0.9995 1490483 ChemDiv1_004609 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B12 compound treatment 278.6 89.1 0.46 278.4 91.8 0.48 0.6661 0.9999 1634864 ChemDiv1_004610 C=CCn1c(SCC(=O)N2CCCCC2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B13 compound treatment 282.2 92.7 0.48 281.0 94.4 0.49 0.6889 1.0 1972564 ChemDiv1_004611 [O-][N+](=O)c1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B14 compound treatment 277.0 87.5 0.46 281.8 95.2 0.49 0.6727 0.9992 1940912 ChemDiv1_004612 C=CCn1c(SCC(=O)NCCCN2CCOCC2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B15 compound treatment 278.0 88.5 0.46 280.4 93.8 0.49 0.6712 0.9996 1972565 ChemDiv1_004613 COC(=O)CSC1=C(C#N)C(CC(=O)N1)c2cc(Br)c(O)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B16 compound treatment 278.2 88.7 0.46 282.6 96.0 0.5 0.6801 0.9993 1972566 ChemDiv1_004614 Cc1nn(C(=O)c2sc3ccccc3c2Cl)c(C)c1Sc4ccccc4[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B17 compound treatment 279.9 90.4 0.47 279.3 92.7 0.48 0.6742 0.9999 1372303 ChemDiv1_004615 Brc1ccc(NC(=O)c2cc3ccccc3oc2=O)c(c1)C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B18 compound treatment 281.0 91.5 0.48 278.1 91.5 0.48 0.6738 1.0 1500447 ChemDiv1_004616 CCN1C(=O)c2cccc3c(NC(=O)c4cc(nc5ccccc45)c6cccs6)ccc1c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B19 compound treatment 281.4 91.9 0.48 275.1 88.5 0.46 0.6643 0.9998 1610800 ChemDiv1_004617 O=C(Nc1nc2c(ccc3ccccc23)s1)c4cc(=O)c5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B20 compound treatment 275.8 86.3 0.45 275.4 88.8 0.46 0.6447 0.9999 1273021 ChemDiv1_004618 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B21 compound treatment 279.3 89.8 0.47 278.9 92.3 0.48 0.6705 0.9999 1972567 ChemDiv1_004619 COc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B22 compound treatment 279.0 89.5 0.47 277.4 90.8 0.47 0.6639 1.0 1599333 ChemDiv1_004620 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B23 mock treatment 281.6 92.1 0.48 279.7 93.1 0.48 0.6819 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 B24 mock treatment 79.8 -110.0 -0.57 82.1 -105.0 -0.54 -0.7887 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C01 compound treatment 284.5 95.0 0.5 282.7 96.1 0.5 0.7037 1.0 1716490 ChemDiv1_004621 CN(C)c1nc(N)nc2ncn(C)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C02 compound treatment 295.8 106.0 0.55 301.7 115.0 0.6 0.8152 0.9993 1924398 ChemDiv1_004622 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)c4cc(ccc4Cl)C(=O)O)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C03 compound treatment 281.1 91.6 0.48 279.2 92.6 0.48 0.6783 1.0 1339681 ChemDiv1_004623 COc1cc(ccc1OC(=O)N(C)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C04 compound treatment 286.2 96.7 0.5 288.6 102.0 0.53 0.7316 0.9997 1972568 ChemDiv1_004624 COc1cccc(c1)C(=O)/C=C\Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C05 compound treatment 286.9 97.4 0.51 283.2 96.6 0.5 0.7143 1.0 1972569 ChemDiv1_004625 CCOC(=O)c1ccc(Nc2nc3nonc3nc2NOC(=O)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C06 compound treatment 280.8 91.3 0.48 280.2 93.6 0.49 0.6808 0.9999 1972570 ChemDiv1_004626 Cc1ccc(cc1)S(=O)(=O)N2C(=O)/C(=C/3\SC(=S)N(CC=C)C3=O)/c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C07 compound treatment 279.6 90.1 0.47 282.7 96.1 0.5 0.6856 0.9995 1241444 ChemDiv1_004627 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C08 compound treatment 281.9 92.4 0.48 282.0 95.4 0.5 0.6915 0.9999 1972571 ChemDiv1_004628 CC(N)C(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(ccc4n2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C09 compound treatment 278.4 88.9 0.46 280.3 93.7 0.49 0.6723 0.9997 1972572 ChemDiv1_004629 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(C)c([N+](=O)[O-])c4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C10 compound treatment 290.2 101.0 0.53 286.7 100.0 0.52 0.7394 1.0 1972573 ChemDiv1_004630 Fc1ccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C11 compound treatment 281.8 92.3 0.48 279.9 93.3 0.48 0.6834 1.0 1714999 ChemDiv1_004631 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C12 compound treatment 280.2 90.7 0.47 276.8 90.2 0.47 0.6661 1.0 1972574 ChemDiv1_004632 COc1ccccc1NC(=O)CCCN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C13 compound treatment 279.2 89.7 0.47 279.7 93.1 0.48 0.6731 0.9999 1930575 ChemDiv1_004633 Cc1ccccc1NC(=O)CSc2nnc(C)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C14 compound treatment 282.6 93.1 0.49 282.5 95.9 0.5 0.6959 0.9999 1972575 ChemDiv1_004634 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3ccccc3C(=O)O)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C15 compound treatment 278.0 88.5 0.46 279.0 92.4 0.48 0.6661 0.9998 1972576 ChemDiv1_004635 CCOC(=O)Cn1nc(C)c2ccccc2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C16 compound treatment 278.0 88.5 0.46 276.1 89.5 0.47 0.6554 1.0 1972577 ChemDiv1_004636 O=C(CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4)NCCCN5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C17 compound treatment 277.4 87.9 0.46 275.9 89.3 0.46 0.6525 1.0 1547279 ChemDiv1_004637 COc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C18 compound treatment 282.8 93.3 0.49 278.1 91.5 0.48 0.6805 0.9999 1508911 ChemDiv1_004638 COC(=O)c1ccc(CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C19 compound treatment 282.4 92.9 0.48 280.4 93.8 0.49 0.6875 1.0 1972578 ChemDiv1_004639 OC(=O)c1ccccc1c2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C20 compound treatment 275.0 85.5 0.45 277.8 91.2 0.47 0.6506 0.9995 1524331 ChemDiv1_004640 COc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C21 compound treatment 277.0 87.5 0.46 278.1 91.5 0.48 0.6591 0.9998 1946942 ChemDiv1_004641 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C\c3ccc(o3)c4ccccc4[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C22 compound treatment 277.9 88.4 0.46 274.9 88.3 0.46 0.6506 1.0 1289875 ChemDiv1_004642 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CC(C)CC(C)C4)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C23 mock treatment 283.8 94.3 0.49 280.2 93.6 0.49 0.6919 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 C24 mock treatment 85.0 -104.0 -0.55 80.2 -106.0 -0.55 -0.7765 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D01 compound treatment 287.8 98.3 0.51 282.9 96.3 0.5 0.7166 0.9999 1972579 ChemDiv1_004643 CC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D02 compound treatment 281.5 92.0 0.48 281.4 94.8 0.49 0.6878 0.9999 1972580 ChemDiv1_004644 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D03 compound treatment 287.2 97.7 0.51 287.4 101.0 0.52 0.7309 0.9999 1155069 ChemDiv1_004645 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D04 compound treatment 288.5 99.0 0.52 284.1 97.5 0.51 0.7236 1.0 1178343 ChemDiv1_004646 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5nc(C)sc5c4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D05 compound treatment 282.6 93.1 0.49 283.0 96.4 0.5 0.6978 0.9999 1164870 ChemDiv1_004647 CC(C)Sc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D06 compound treatment 280.9 91.4 0.48 282.8 96.2 0.5 0.6907 0.9997 1948716 ChemDiv1_004648 Fc1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D07 compound treatment 282.6 93.1 0.49 282.0 95.4 0.5 0.6941 0.9999 1972581 ChemDiv1_004649 Clc1ccc(C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D08 compound treatment 282.4 92.9 0.48 279.7 93.1 0.48 0.6849 1.0 1972582 ChemDiv1_004650 FC(F)(F)c1cccc(NC(=O)CSc2nnc3ccccn23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D09 compound treatment 281.7 92.2 0.48 283.1 96.5 0.5 0.6948 0.9998 1972583 ChemDiv1_004651 CCCCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OCC)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D10 compound treatment 277.5 88.0 0.46 280.2 93.6 0.49 0.6686 0.9996 1949763 ChemDiv1_004652 OC(=O)/C=C/c1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)C4C5CC(C=C5)C4C3=O)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D11 compound treatment 280.6 91.1 0.48 279.4 92.8 0.48 0.6771 1.0 1359872 ChemDiv1_004653 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D12 compound treatment 276.5 87.0 0.45 279.6 93.0 0.48 0.6628 0.9995 1395902 ChemDiv1_004654 C=CCn1c(SCC(=O)NCc2ccco2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D13 compound treatment 283.3 93.8 0.49 277.9 91.3 0.47 0.6816 0.9999 1972584 ChemDiv1_004655 Clc1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D14 compound treatment 280.1 90.6 0.47 280.2 93.6 0.49 0.6782 0.9999 1972585 ChemDiv1_004656 OCCCNC(=O)c1ccc(CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D15 compound treatment 281.2 91.7 0.48 281.5 94.9 0.49 0.6871 0.9999 1972586 ChemDiv1_004657 CCCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2cc(Br)c(O)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D16 compound treatment 280.1 90.6 0.47 278.5 91.9 0.48 0.672 1.0 1972587 ChemDiv1_004658 CC(C)N(C(=O)CSc1nnc(COc2ccc(Cl)cc2Cl)o1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D17 compound treatment 277.0 87.5 0.46 279.3 92.7 0.48 0.6635 0.9996 1137778 ChemDiv1_004659 CCOC(=O)c1sc(cc1NC(=O)c2cc3ccccc3oc2=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D18 compound treatment 276.0 86.5 0.45 278.7 92.1 0.48 0.6576 0.9996 1257943 ChemDiv1_004660 CSc1nc2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCOCC4)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D19 compound treatment 282.2 92.7 0.48 281.7 95.1 0.49 0.6915 0.9999 1559252 ChemDiv1_004661 O=C(Nc1nc(cs1)c2cc3ccccc3oc2=O)c4cc(=O)c5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D20 compound treatment 282.3 92.8 0.48 278.4 91.8 0.48 0.6797 1.0 1278691 ChemDiv1_004662 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D21 compound treatment 275.9 86.4 0.45 277.4 90.8 0.47 0.6525 0.9997 1972588 ChemDiv1_004663 OC(=O)CCC(=O)N1N=C(CC1c2ccco2)c3c(O)nc4ccc(Br)cc4c3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D22 compound treatment 280.0 90.5 0.47 277.3 90.7 0.47 0.6672 1.0 1308274 ChemDiv1_004664 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D23 mock treatment 281.0 91.5 0.48 277.8 91.2 0.47 0.6727 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 D24 mock treatment 77.7 -112.0 -0.58 83.4 -103.0 -0.54 -0.7917 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E01 compound treatment 282.8 93.3 0.49 283.4 96.8 0.5 0.7 0.9999 1195375 ChemDiv1_004665 Cc1cc(C)n(n1)c2nc3nonc3nc2Nc4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E02 compound treatment 282.1 92.6 0.48 285.1 98.5 0.51 0.7036 0.9996 1972589 ChemDiv1_004666 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(cc4)c5cnc(nc5)c6ccc(cc6)N7C(=O)C8C9CC(C=C9)C8C7=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E03 compound treatment 292.3 103.0 0.54 291.4 105.0 0.54 0.7644 1.0 1689319 ChemDiv1_004667 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(OC)c1OC(=O)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E04 compound treatment 283.2 93.7 0.49 282.7 96.1 0.5 0.6989 0.9999 1972590 ChemDiv1_004668 Clc1ccc(CN2C(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E05 compound treatment 399.2 210.0 1.09 398.6 212.0 1.1 1.5527 1.0 1972591 ChemDiv1_004669 Fc1ccc(c2ccc(/C=C/3\Sc4ccccc4C3=O)o2)c(F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E06 compound treatment 284.4 94.9 0.5 281.0 94.4 0.49 0.697 1.0 1972592 ChemDiv1_004670 Cc1ccc(cc1)S(=O)(=O)N2C(=O)/C(=C/3\SC(=S)N(Cc4ccco4)C3=O)/c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E07 compound treatment 283.6 94.1 0.49 280.7 94.1 0.49 0.693 1.0 1972593 ChemDiv1_004671 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E08 compound treatment 282.5 93.0 0.49 278.1 91.5 0.48 0.6794 0.9999 1426744 ChemDiv1_004672 Fc1ccc(Cc2cnc(NC(=O)c3csc4CCCCc34)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E09 compound treatment 278.2 88.7 0.46 281.2 94.6 0.49 0.6749 0.9995 1972594 ChemDiv1_004673 [O-][N+](=O)c1cc(C(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)c(Cl)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E10 compound treatment 328.3 139.0 0.72 329.3 143.0 0.74 1.0365 0.9999 1951684 ChemDiv1_004674 Oc1ccc(Cl)cc1NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E11 compound treatment 283.8 94.3 0.49 283.1 96.5 0.5 0.7025 1.0 1484799 ChemDiv1_004675 OCCNC(=O)Cc1n[nH]c(=O)c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E12 compound treatment 275.2 85.7 0.45 282.6 96.0 0.5 0.669 0.9985 1972595 ChemDiv1_004676 OC(=O)c1ccc(NC(=O)CCCN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E13 compound treatment 283.0 93.5 0.49 281.4 94.8 0.49 0.6933 1.0 1972596 ChemDiv1_004677 Cc1ccc(NC(=O)CSc2nnc(C)c3ccccc23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E14 compound treatment 279.0 89.5 0.47 283.1 96.5 0.5 0.6848 0.9994 1972597 ChemDiv1_004678 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3nnc(CC(C)C)s3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E15 compound treatment 278.9 89.4 0.47 276.5 89.9 0.47 0.6602 1.0 1284873 ChemDiv1_004679 CC(=O)Nc1ccc(Oc2nnc(c3ccccc3)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E16 compound treatment 274.6 85.1 0.44 277.6 91.0 0.47 0.6484 0.9995 1941241 ChemDiv1_004680 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6ccccn6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E17 compound treatment 280.0 90.5 0.47 280.2 93.6 0.49 0.6779 0.9999 1458322 ChemDiv1_004681 COc1ccc(cc1)c2nnc(OC)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E18 compound treatment 280.4 90.9 0.47 278.7 92.1 0.48 0.6738 1.0 1945419 ChemDiv1_004682 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E19 compound treatment 287.9 98.4 0.51 281.8 95.2 0.49 0.7129 0.9998 1972598 ChemDiv1_004683 COc1cc(ccc1c2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)o2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E20 compound treatment 281.2 91.7 0.48 274.9 88.3 0.46 0.6628 0.9998 1297436 ChemDiv1_004684 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E21 compound treatment 281.8 92.3 0.48 279.5 92.9 0.48 0.6819 1.0 1946487 ChemDiv1_004685 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccc(Br)o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E22 compound treatment 276.6 87.1 0.45 278.9 92.3 0.48 0.6606 0.9996 1315776 ChemDiv1_004686 CCOc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CC(C)CC(C)C4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E23 mock treatment 280.8 91.3 0.48 282.6 96.0 0.5 0.6896 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 E24 mock treatment 78.5 -111.0 -0.58 78.8 -108.0 -0.56 -0.8057 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F01 compound treatment 280.1 90.6 0.47 283.9 97.3 0.51 0.6918 0.9994 1972599 ChemDiv1_004687 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F02 compound treatment 281.5 92.0 0.48 281.7 95.1 0.49 0.6889 0.9999 1946341 ChemDiv1_004688 COc1ccc(cc1)C(=O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F03 compound treatment 283.3 93.8 0.49 279.5 92.9 0.48 0.6875 1.0 1280694 ChemDiv1_004689 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F04 compound treatment 285.2 95.7 0.5 287.2 101.0 0.52 0.7228 0.9997 1972600 ChemDiv1_004690 [O-][N+](=O)c1csc(c1)c2csc(NC(=O)c3cc(nc4ccccc34)c5cccs5)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F05 compound treatment 282.3 92.8 0.48 283.2 96.6 0.5 0.6974 0.9998 1782841 ChemDiv1_004691 CN1CCN(CC1)c2nc3n(C)c(=O)[nH]c(=O)c3n2CC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F06 compound treatment 282.0 92.5 0.48 281.7 95.1 0.49 0.6908 0.9999 1972601 ChemDiv1_004692 Fc1ccc(cc1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F07 compound treatment 280.6 91.1 0.48 281.9 95.3 0.5 0.6863 0.9998 1160082 ChemDiv1_004693 CCOC(=O)c1sc2nc(N)c(C#N)c(c3ccc(OCC)cc3)c2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F08 compound treatment 282.9 93.4 0.49 284.5 97.9 0.51 0.7044 0.9998 1972602 ChemDiv1_004694 Cc1cc2nnc(SCC(=O)Nc3ccc(F)cc3)n2c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F09 compound treatment 282.0 92.5 0.48 280.6 94.0 0.49 0.6867 1.0 1972603 ChemDiv1_004695 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)OCc3ccccc3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F10 compound treatment 280.8 91.3 0.48 283.5 96.9 0.5 0.693 0.9996 1940853 ChemDiv1_004696 OCCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F11 compound treatment 282.9 93.4 0.49 288.2 102.0 0.53 0.718 0.9992 1526154 ChemDiv1_004697 COc1ccc(cc1)C(=O)c2sc3nc(N)c(C#N)c(c4ccc(OC)cc4)c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F12 compound treatment 278.9 89.4 0.47 278.2 91.6 0.48 0.6665 0.9999 1697403 ChemDiv1_004698 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F13 compound treatment 279.7 90.2 0.47 284.1 97.5 0.51 0.6911 0.9993 1223221 ChemDiv1_004699 CCOC(=O)c1sc2nc(N)c(C#N)c(c3ccc(OC)c(OC)c3)c2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F14 compound treatment 277.3 87.8 0.46 276.6 90.0 0.47 0.6547 0.9999 1712761 ChemDiv1_004700 OCCNC(=O)c1ccc(CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F15 compound treatment 274.0 84.5 0.44 273.6 87.0 0.45 0.6315 0.9999 1972604 ChemDiv1_004701 CCOc1ccc(cc1)C2C(C(=O)OC)C(=O)NC(=C2C#N)SCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F16 compound treatment 278.0 88.5 0.46 277.1 90.5 0.47 0.6591 1.0 1972605 ChemDiv1_004702 CCNc1nc(NCC)n2c(SCC(=O)c3ccc(cc3)C(C)C)nnc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F17 compound treatment 282.9 93.4 0.49 283.3 96.7 0.5 0.7 0.9999 1972606 ChemDiv1_004703 [O-][N+](=O)c1ccc2sc(cc2c1)C(=O)Nc3nc(cs3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F18 compound treatment 276.5 87.0 0.45 278.1 91.5 0.48 0.6572 0.9997 1972607 ChemDiv1_004704 FC(F)(F)C(=O)c1sc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)nc1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F19 compound treatment 279.0 89.5 0.47 276.4 89.8 0.47 0.6602 1.0 1572199 ChemDiv1_004705 CCOC(=O)c1sc(NC(=O)c2cc(=O)c3ccccc3o2)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F20 compound treatment 281.3 91.8 0.48 283.0 96.4 0.5 0.693 0.9997 1656582 ChemDiv1_004706 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F21 compound treatment 282.7 93.2 0.49 281.6 95.0 0.49 0.693 1.0 1251575 ChemDiv1_004707 CCN(CC)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F22 compound treatment 275.8 86.3 0.45 275.8 89.2 0.46 0.6462 0.9999 1330313 ChemDiv1_004708 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F23 mock treatment 275.2 85.7 0.45 279.7 93.1 0.48 0.6583 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 F24 mock treatment 81.2 -108.0 -0.56 78.9 -108.0 -0.56 -0.7953 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G01 compound treatment 286.0 96.5 0.5 287.8 101.0 0.53 0.7279 0.9998 1511107 ChemDiv1_004709 Cc1cccc(Nc2nc3nonc3nc2N4CCCCC4)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G02 compound treatment 281.4 91.9 0.48 283.3 96.7 0.5 0.6944 0.9997 1972608 ChemDiv1_004710 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(cc3)c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G03 compound treatment 318.6 129.0 0.67 327.8 141.0 0.73 0.9952 0.9991 1972609 ChemDiv1_004711 COc1cc(/C=C/2\S/C(=N\c3ccc4OCOc4c3)/N(C2=O)c5ccc6OCOc6c5)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G04 compound treatment 283.2 93.7 0.49 280.1 93.5 0.49 0.6893 1.0 1972610 ChemDiv1_004712 [O-][N+](=O)c1ccc2NC(=O)/C(=C/3\SC(=S)N(Cc4ccc(Cl)cc4)C3=O)/c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G05 compound treatment 335.9 146.0 0.76 331.1 144.0 0.75 1.0712 1.0 1431118 ChemDiv1_004713 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc(Br)c1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G06 compound treatment 281.1 91.6 0.48 285.5 98.9 0.51 0.7014 0.9993 1320036 ChemDiv1_004714 CC(=O)N(Cc1nc2ccccc2c3nc4ccccc4n13)c5ccccc5Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G07 compound treatment 282.1 92.6 0.48 285.6 99.0 0.51 0.7055 0.9995 1972611 ChemDiv1_004715 [O-][N+](=O)c1ccc(/C=C/C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G08 compound treatment 279.7 90.2 0.47 285.2 98.6 0.51 0.6951 0.9991 1972612 ChemDiv1_004716 CCc1nnc(/N=C\2/S\C(=C/c3ccccc3F)\C(=O)N2CC=C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G09 compound treatment 285.1 95.6 0.5 281.1 94.5 0.49 0.7 1.0 1972613 ChemDiv1_004717 O=C(Nn1c(nc2ccccc2c1=O)c3cccs3)c4cc5ccccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G10 compound treatment 314.1 125.0 0.65 314.7 128.0 0.67 0.9305 0.9999 1928130 ChemDiv1_004718 OC(=O)c1cccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G11 compound treatment 279.9 90.4 0.47 280.5 93.9 0.49 0.6786 0.9999 1557433 ChemDiv1_004719 O=C(CSc1nc2ccccc2o1)NCc3n[nH]c(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G12 compound treatment 285.9 96.4 0.5 281.5 94.9 0.49 0.7044 1.0 1928020 ChemDiv1_004720 Brc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NCCCN3CCOCC3)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G13 compound treatment 280.1 90.6 0.47 281.8 95.2 0.49 0.6841 0.9997 1972614 ChemDiv1_004721 Cc1ccc(C)c(NC(=O)CSc2nnc(C)c3ccccc23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G14 compound treatment 287.5 98.0 0.51 285.2 98.6 0.51 0.7239 1.0 1972615 ChemDiv1_004722 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3ncc(Cc4ccccc4Cl)s3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G15 compound treatment 281.0 91.5 0.48 280.0 93.4 0.49 0.6808 1.0 1463821 ChemDiv1_004723 COc1ccc(cc1)c2nnc(N3CCOCC3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G16 compound treatment 276.0 86.5 0.45 279.6 93.0 0.48 0.6609 0.9994 1941131 ChemDiv1_004724 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCn6ccnc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G17 compound treatment 279.0 89.5 0.47 280.7 94.1 0.49 0.676 0.9997 1486653 ChemDiv1_004725 COc1ccc(cc1)c2nnc(N3CCCCC3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G18 compound treatment 278.9 89.4 0.47 278.3 91.7 0.48 0.6668 0.9999 1945357 ChemDiv1_004726 CCOC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G19 compound treatment 282.9 93.4 0.49 288.7 102.0 0.53 0.7198 0.9991 1927371 ChemDiv1_004727 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cc(C)cc(C)c3)cc(OC)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G20 compound treatment 273.2 83.7 0.44 271.7 85.1 0.44 0.6215 1.0 1873276 ChemDiv1_004728 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)OC)C#N)c2ccccc2OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G21 compound treatment 280.0 90.5 0.47 279.9 93.3 0.48 0.6768 0.9999 1946662 ChemDiv1_004729 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccc(o3)c4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G22 compound treatment 277.5 88.0 0.46 277.2 90.6 0.47 0.6576 0.9999 1674741 ChemDiv1_004730 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(Cl)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G23 mock treatment 279.8 90.3 0.47 277.2 90.6 0.47 0.6661 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 G24 mock treatment 76.0 -113.0 -0.59 75.0 -112.0 -0.58 -0.8288 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H01 compound treatment 283.9 94.4 0.49 287.4 101.0 0.52 0.7187 0.9995 1972616 ChemDiv1_004731 OC(=O)CCC(=O)N1N=C(CC1c2ccc(Br)cc2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H02 compound treatment 284.1 94.6 0.49 282.6 96.0 0.5 0.7018 1.0 1941000 ChemDiv1_004732 Fc1ccc(cc1)C(=O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H03 compound treatment 283.7 94.2 0.49 284.6 98.0 0.51 0.7077 0.9998 1191359 ChemDiv1_004733 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H04 compound treatment 280.7 91.2 0.48 279.5 92.9 0.48 0.6779 1.0 1941214 ChemDiv1_004734 OCCCNC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H05 compound treatment 280.7 91.2 0.48 278.9 92.3 0.48 0.6757 1.0 1782845 ChemDiv1_004735 CN1CCN(CC1)c2nc3n(C)c(=O)[nH]c(=O)c3n2CC(O)COc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H06 compound treatment 281.8 92.3 0.48 283.2 96.6 0.5 0.6955 0.9998 1972617 ChemDiv1_004736 COc1ccc(cc1)C(=O)CSc2nnc(c3ccc4OCOc4c3)n2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H07 compound treatment 282.8 93.3 0.49 284.2 97.6 0.51 0.7029 0.9998 1661403 ChemDiv1_004737 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(Br)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H08 compound treatment 280.9 91.4 0.48 286.4 99.8 0.52 0.704 0.9991 1972618 ChemDiv1_004738 Brc1ccc(NC(=O)CSc2nnc3ccccn23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H09 compound treatment 281.5 92.0 0.48 283.3 96.7 0.5 0.6948 0.9997 1972619 ChemDiv1_004739 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccccc3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H10 compound treatment 280.1 90.6 0.47 281.8 95.2 0.49 0.6841 0.9997 1949850 ChemDiv1_004740 O=C(CN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(CCN5C(=O)C6C7CC(C=C7)C6C5=O)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H11 compound treatment 232.9 43.4 0.23 215.2 28.6 0.15 0.2652 0.9791 1288245 ChemDiv1_004741 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(Cl)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H12 compound treatment 281.7 92.2 0.48 280.6 94.0 0.49 0.6856 1.0 1527352 ChemDiv1_004742 OCCN(CCO)C(=O)CSc1nc2sc3CCCc3c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H13 compound treatment 282.1 92.6 0.48 282.2 95.6 0.5 0.693 0.9999 1716831 ChemDiv1_004743 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)N)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H14 compound treatment 278.9 89.4 0.47 278.4 91.8 0.48 0.6672 0.9999 1725986 ChemDiv1_004744 C=CCn1c(SCC(=O)N2CCCCC2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H15 compound treatment 282.3 92.8 0.48 280.8 94.2 0.49 0.6886 1.0 1432560 ChemDiv1_004745 CC1CCc2nc(NC(=O)c3cc(=O)c4ccccc4o3)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H16 compound treatment 279.0 89.5 0.47 279.6 93.0 0.48 0.672 0.9999 1972620 ChemDiv1_004746 CCNc1nc(NCC)n2c(SCC(=O)c3ccc(cc3)C(C)(C)C)nnc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H17 compound treatment 280.0 90.5 0.47 283.3 96.7 0.5 0.6893 0.9995 1972621 ChemDiv1_004747 Oc1ccc(NC(=O)c2cc3cc(ccc3s2)[N+](=O)[O-])cc1c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H18 compound treatment 280.1 90.6 0.47 278.7 92.1 0.48 0.6727 1.0 1563078 ChemDiv1_004748 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCc5ccccc45)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H19 compound treatment 279.7 90.2 0.47 282.9 96.3 0.5 0.6867 0.9995 1470888 ChemDiv1_004749 O=C(Nc1nc(cs1)c2ccc3OCOc3c2)c4cc(=O)c5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H20 compound treatment 279.5 90.0 0.47 279.0 92.4 0.48 0.6716 0.9999 1682202 ChemDiv1_004750 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H21 compound treatment 284.0 94.5 0.49 286.8 100.0 0.52 0.7169 0.9996 1599263 ChemDiv1_004751 CCN(CC)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H22 compound treatment 275.0 85.5 0.45 277.9 91.3 0.47 0.651 0.9995 1417710 ChemDiv1_004752 COc1ccc(cc1)C2=NN(C(C2)c3cc(OC)ccc3OC)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H23 mock treatment 279.4 89.9 0.47 280.1 93.5 0.49 0.6753 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 H24 mock treatment 76.2 -113.0 -0.59 77.3 -109.0 -0.57 -0.8197 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I01 compound treatment 284.5 95.0 0.5 286.1 99.5 0.52 0.7162 0.9998 1694352 ChemDiv1_004753 Cc1ccccc1Nc2nc3nonc3nc2N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I02 compound treatment 283.5 94.0 0.49 284.9 98.3 0.51 0.7081 0.9998 1946250 ChemDiv1_004754 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4ccc(cc4)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I03 compound treatment 288.3 98.8 0.52 291.4 105.0 0.54 0.7497 0.9996 1972622 ChemDiv1_004755 Cc1ccc2c(nc3sc(=Cc4cc([N+](=O)[O-])c(cc4N5CCOCC5)N6CCOCC6)c(=O)n32)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I04 compound treatment 279.8 90.3 0.47 288.2 102.0 0.53 0.7065 0.9984 1972623 ChemDiv1_004756 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\3/C(=O)Nc4ccc(Cl)cc34)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I05 compound treatment 333.3 144.0 0.75 315.9 129.0 0.67 1.0057 0.9985 1942668 ChemDiv1_004757 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc3sc(=O)oc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I06 compound treatment 277.1 87.6 0.46 285.2 98.6 0.51 0.6856 0.9984 1308050 ChemDiv1_004758 c1c(nc2c3ccccc3ccn12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I07 compound treatment 284.1 94.6 0.49 283.7 97.1 0.5 0.7059 0.9999 1554519 ChemDiv1_004759 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I08 compound treatment 284.2 94.7 0.49 287.5 101.0 0.52 0.7202 0.9996 1942602 ChemDiv1_004760 Brc1ccccc1C(=O)NN2C(=O)/C(=C\3/C(=O)Nc4ccccc34)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I09 compound treatment 277.1 87.6 0.46 285.7 99.1 0.52 0.6874 0.9982 1972624 ChemDiv1_004761 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I10 compound treatment 300.9 111.0 0.58 303.6 117.0 0.61 0.841 0.9997 1972625 ChemDiv1_004762 O=C(CCN1C(=O)/C(=C\c2cccs2)/SC1=S)Nc3ccccn3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I11 compound treatment 280.1 90.6 0.47 281.0 94.4 0.49 0.6812 0.9998 1328429 ChemDiv1_004763 Cc1nnc(Nc2ccccc2O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I12 compound treatment 281.5 92.0 0.48 284.1 97.5 0.51 0.6977 0.9996 1972626 ChemDiv1_004764 CC(=O)N1C(=O)/C(=C/2\SC(=NC2=O)Nc3ccc(Br)cc3)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I13 compound treatment 290.4 101.0 0.53 289.6 103.0 0.54 0.7508 1.0 1972627 ChemDiv1_004765 Cc1nnc(SCC(=O)Nc2ccc(Cl)c(Cl)c2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I14 compound treatment 280.2 90.7 0.47 287.2 101.0 0.52 0.7043 0.9988 1972628 ChemDiv1_004766 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3nc4ccccc4s3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I15 compound treatment 280.4 90.9 0.47 280.5 93.9 0.49 0.6804 0.9999 1179090 ChemDiv1_004767 CCCOC(=O)c1ccc(cc1)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I16 compound treatment 280.6 91.1 0.48 281.5 94.9 0.49 0.6849 0.9998 1948540 ChemDiv1_004768 Cc1sc2nc(SCC(=O)NCCCN3CCOCC3)n(c4ccccc4)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I17 compound treatment 281.7 92.2 0.48 277.7 91.1 0.47 0.675 1.0 1239167 ChemDiv1_004769 COc1ccc(cc1)c2nnc(NCc3nc4ccccc4[nH]3)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I18 compound treatment 281.3 91.8 0.48 278.4 91.8 0.48 0.676 1.0 1945961 ChemDiv1_004770 CCOC(=O)CSc1nnc(c2ccncc2)n1c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I19 compound treatment 284.6 95.1 0.5 281.2 94.6 0.49 0.6985 1.0 1972629 ChemDiv1_004771 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)cc(OC)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I20 compound treatment 280.8 91.3 0.48 276.7 90.1 0.47 0.668 1.0 1873278 ChemDiv1_004772 CCOC(=O)CSC1=C(C#N)C(C(C(=O)OCC)C(=O)N1)c2ccccc2OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I21 compound treatment 282.6 93.1 0.49 281.3 94.7 0.49 0.6915 1.0 1947065 ChemDiv1_004773 COc1cc(ccc1c2ccc(/C=C\3/C(=C(C#N)c4nc(N)c(C#N)c(C)c34)C)o2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I22 compound treatment 275.9 86.4 0.45 278.6 92.0 0.48 0.6569 0.9996 1230321 ChemDiv1_004774 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(Br)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I23 mock treatment 282.3 92.8 0.48 278.9 92.3 0.48 0.6816 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 I24 mock treatment 80.1 -109.0 -0.57 80.6 -106.0 -0.55 -0.7931 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J01 compound treatment 284.2 94.7 0.49 286.1 99.5 0.52 0.715 0.9997 1273795 ChemDiv1_004775 NS(=O)(=O)c1ccc2nc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J02 compound treatment 280.3 90.8 0.47 284.5 97.9 0.51 0.6948 0.9994 1972630 ChemDiv1_004776 Fc1ccc(cc1)c2csc(NC(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J03 compound treatment 286.7 97.2 0.51 281.9 95.3 0.5 0.7088 0.9999 1519314 ChemDiv1_004777 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J04 compound treatment 281.3 91.8 0.48 279.7 93.1 0.48 0.6808 1.0 1972631 ChemDiv1_004778 OCCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J05 compound treatment 279.6 90.1 0.47 278.2 91.6 0.48 0.669 1.0 1940699 ChemDiv1_004779 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J06 compound treatment 288.5 99.0 0.52 282.4 95.8 0.5 0.7173 0.9998 1156589 ChemDiv1_004780 C=CCSc1nc2ccccc2n1C(=O)CN3C(=O)c4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J07 compound treatment 279.0 89.5 0.47 277.8 91.2 0.47 0.6654 1.0 1400349 ChemDiv1_004781 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J08 compound treatment 282.3 92.8 0.48 286.7 100.0 0.52 0.7102 0.9994 1972632 ChemDiv1_004782 Cc1ccc(cc1C)c2nnc(SC(F)F)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J09 compound treatment 281.4 91.9 0.48 285.5 98.9 0.51 0.7025 0.9994 1972633 ChemDiv1_004783 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(C)cc3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J10 compound treatment 281.9 92.4 0.48 281.5 94.9 0.49 0.6897 0.9999 1478057 ChemDiv1_004784 C=CCn1c(SCC(=O)NCc2cccnc2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J11 compound treatment 282.2 92.7 0.48 282.9 96.3 0.5 0.6959 0.9999 1972634 ChemDiv1_004785 CCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OC)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J12 compound treatment 278.7 89.2 0.47 281.2 94.6 0.49 0.6768 0.9996 1210944 ChemDiv1_004786 Cc1sc2nc(SCC(=O)N3CCN(CCO)CC3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J13 compound treatment 276.1 86.6 0.45 277.9 91.3 0.47 0.655 0.9997 1217980 ChemDiv1_004787 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(Br)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J14 compound treatment 276.7 87.2 0.45 280.9 94.3 0.49 0.6683 0.9993 1540046 ChemDiv1_004788 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)C4C5CC(C=C5)C4C3=O)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J15 compound treatment 282.0 92.5 0.48 279.0 92.4 0.48 0.6808 1.0 1687347 ChemDiv1_004789 Brc1ccc(cc1)c2csc(NC(=O)c3cc(=O)c4ccccc4o3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J16 compound treatment 279.6 90.1 0.47 281.0 94.4 0.49 0.6793 0.9998 1972635 ChemDiv1_004790 CCNc1nc(NCC)n2c(SCC(=O)N(C(C)C)c3ccccc3)nnc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J17 compound treatment 284.8 95.3 0.5 281.2 94.6 0.49 0.6993 1.0 1972636 ChemDiv1_004791 [O-][N+](=O)c1ccc2sc(cc2c1)C(=O)Nc3ccc(Cl)cc3C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J18 compound treatment 275.7 86.2 0.45 277.0 90.4 0.47 0.6502 0.9998 1246111 ChemDiv1_004792 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J19 compound treatment 279.3 89.8 0.47 276.6 90.0 0.47 0.6621 1.0 1642814 ChemDiv1_004793 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3CCC(C)Cc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J20 compound treatment 280.8 91.3 0.48 278.7 92.1 0.48 0.6753 1.0 1692422 ChemDiv1_004794 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J21 compound treatment 277.5 88.0 0.46 285.4 98.8 0.51 0.6878 0.9984 1163233 ChemDiv1_004795 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J22 compound treatment 277.5 88.0 0.46 280.0 93.4 0.49 0.6679 0.9996 1221586 ChemDiv1_004796 COc1ccc(cc1)C2=NN(C(C2)c3cc4ccc(C)cc4nc3Cl)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J23 mock treatment 282.6 93.1 0.49 277.4 90.8 0.47 0.6772 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 J24 mock treatment 76.9 -113.0 -0.59 79.5 -107.0 -0.56 -0.809 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K01 compound treatment 283.2 93.7 0.49 286.4 99.8 0.52 0.7125 0.9996 1421740 ChemDiv1_004797 CC(C)Nc1nc2nonc2nc1Nc3cccc(C)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K02 compound treatment 283.1 93.6 0.49 284.0 97.4 0.51 0.7033 0.9998 1972637 ChemDiv1_004798 CCN1C(=O)c2ccc(cc2C1=O)c3ccc(/C=C/4\C(=NN(C4=O)c5ccc(cc5)C(=O)O)C)o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K03 compound treatment 293.8 104.0 0.54 290.8 104.0 0.54 0.7677 1.0 1509448 ChemDiv1_004799 COc1cc(ccc1OC(=O)N(C)C)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K04 compound treatment 284.3 94.8 0.49 281.5 94.9 0.49 0.6985 1.0 1972638 ChemDiv1_004800 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\3/C(=O)Nc4ccc(cc34)[N+](=O)[O-])/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K05 compound treatment 286.0 96.5 0.5 280.6 94.0 0.49 0.7015 0.9999 1972639 ChemDiv1_004801 Cc1ccc(Nc2nc3nonc3nc2Nc4ccccc4OC(=O)c5ccccc5)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K06 compound treatment 289.6 100.0 0.52 284.5 97.9 0.51 0.7291 0.9999 1426065 ChemDiv1_004802 Clc1ccc(cc1)c2cn3ccc4ccccc4c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K07 compound treatment 282.5 93.0 0.49 279.7 93.1 0.48 0.6853 1.0 1353631 ChemDiv1_004803 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)COc4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K08 compound treatment 281.1 91.6 0.48 278.2 91.6 0.48 0.6746 1.0 1922566 ChemDiv1_004804 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3cccc(Br)c3)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K09 compound treatment 283.2 93.7 0.49 282.1 95.5 0.5 0.6967 1.0 1972640 ChemDiv1_004805 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K10 compound treatment 294.5 105.0 0.55 294.6 108.0 0.56 0.7843 0.9999 1923919 ChemDiv1_004806 O=C(CCN1C(=O)/C(=C/c2cccs2)/SC1=S)NC3(CC4CC5CC(C4)C3)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K11 compound treatment 284.8 95.3 0.5 281.5 94.9 0.49 0.7004 1.0 1672206 ChemDiv1_004807 Cc1nnc(Nc2ccc(cc2)C(=O)NCCO)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K12 compound treatment 284.6 95.1 0.5 277.7 91.1 0.47 0.6856 0.9997 1928039 ChemDiv1_004808 CCOc1ccccc1NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K13 compound treatment 280.3 90.8 0.47 280.6 94.0 0.49 0.6804 0.9999 1972641 ChemDiv1_004809 Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2Cl)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K14 compound treatment 277.3 87.8 0.46 281.4 94.8 0.49 0.6723 0.9993 1940864 ChemDiv1_004810 CCOC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K15 compound treatment 281.4 91.9 0.48 282.6 96.0 0.5 0.6919 0.9998 1972642 ChemDiv1_004811 CCCCOC(=O)c1ccc(cc1)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K16 compound treatment 279.4 89.9 0.47 278.4 91.8 0.48 0.669 1.0 1941229 ChemDiv1_004812 Cc1sc2nc(SCC(=O)NCCO)n(c3ccccc3)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K17 compound treatment 282.5 93.0 0.49 283.6 97.0 0.5 0.6996 0.9998 1972643 ChemDiv1_004813 COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K18 compound treatment 276.4 86.9 0.45 284.2 97.6 0.51 0.6793 0.9984 1972644 ChemDiv1_004814 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCCCN4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K19 compound treatment 280.6 91.1 0.48 277.9 91.3 0.47 0.6716 1.0 1972645 ChemDiv1_004815 OC(=O)c1ccccc1c2ccc(/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc(F)cc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K20 compound treatment 279.4 89.9 0.47 278.0 91.4 0.48 0.6676 1.0 1452858 ChemDiv1_004816 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4cccc(F)c4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K21 compound treatment 278.5 89.0 0.46 282.7 96.1 0.5 0.6815 0.9993 1946730 ChemDiv1_004817 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccc(o3)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K22 compound treatment 279.9 90.4 0.47 281.5 94.9 0.49 0.6823 0.9997 1413062 ChemDiv1_004818 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K23 mock treatment 280.6 91.1 0.48 279.9 93.3 0.48 0.679 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 K24 mock treatment 88.0 -101.0 -0.53 78.4 -108.0 -0.56 -0.7721 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L01 compound treatment 282.2 92.7 0.48 284.5 97.9 0.51 0.7018 0.9997 1787254 ChemDiv1_004819 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L02 compound treatment 285.4 95.9 0.5 279.9 93.3 0.48 0.6967 0.9999 1972646 ChemDiv1_004820 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45)cc2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L03 compound treatment 283.9 94.4 0.49 289.4 103.0 0.53 0.7261 0.9992 1612624 ChemDiv1_004821 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L04 compound treatment 284.5 95.0 0.5 283.0 96.4 0.5 0.7048 1.0 1948876 ChemDiv1_004822 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L05 compound treatment 279.3 89.8 0.47 281.7 95.1 0.49 0.6808 0.9996 1943902 ChemDiv1_004823 O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L06 compound treatment 278.9 89.4 0.47 280.8 94.2 0.49 0.676 0.9997 1509679 ChemDiv1_004824 Cc1ccc(Sc2c(nc3ccccn23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L07 compound treatment 283.1 93.6 0.49 281.8 95.2 0.49 0.6952 1.0 1252445 ChemDiv1_004825 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L08 compound treatment 282.2 92.7 0.48 281.5 94.9 0.49 0.6908 1.0 1275320 ChemDiv1_004826 Cc1ccc(cc1C)c2nnc(n3nnc4ccccc34)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L09 compound treatment 283.5 94.0 0.49 281.7 95.1 0.49 0.6963 1.0 1972647 ChemDiv1_004827 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(OC)cc3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L10 compound treatment 282.0 92.5 0.48 280.1 93.5 0.49 0.6849 1.0 1972648 ChemDiv1_004828 Cc1sc2nc(SCC(=O)NCc3ccco3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L11 compound treatment 281.6 92.1 0.48 282.3 95.7 0.5 0.6915 0.9999 1972649 ChemDiv1_004829 CCCCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OC)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L12 compound treatment 281.7 92.2 0.48 287.1 100.0 0.52 0.7095 0.9992 1940960 ChemDiv1_004830 O=C(CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6ccco6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L13 compound treatment 288.8 99.3 0.52 291.4 105.0 0.54 0.7515 0.9997 1383626 ChemDiv1_004831 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L14 compound treatment 280.3 90.8 0.47 277.2 90.6 0.47 0.668 1.0 1212649 ChemDiv1_004832 Cc1sc2nc(SCc3ccc(cc3)C(=O)NCCO)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L15 compound treatment 285.1 95.6 0.5 281.9 95.3 0.5 0.7029 1.0 1972650 ChemDiv1_004833 Brc1ccc(s1)c2csc(NC(=O)c3cc(=O)c4ccccc4o3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L16 compound treatment 283.0 93.5 0.49 281.2 94.6 0.49 0.6926 1.0 1647746 ChemDiv1_004834 CCc1nnc2sc(nn12)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L17 compound treatment 277.6 88.1 0.46 280.5 93.9 0.49 0.6701 0.9996 1972651 ChemDiv1_004835 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(cc4s3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L18 compound treatment 279.2 89.7 0.47 275.7 89.1 0.46 0.6584 1.0 1972652 ChemDiv1_004836 OC(=O)CCCC(=O)N1N=C(CC1c2ccc(Cl)cc2)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L19 compound treatment 280.7 91.2 0.48 277.4 90.8 0.47 0.6702 1.0 1939962 ChemDiv1_004837 CC(=O)Nc1ccc(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L20 compound treatment 277.5 88.0 0.46 278.1 91.5 0.48 0.6609 0.9998 1217188 ChemDiv1_004838 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L21 compound treatment 279.0 89.5 0.47 275.6 89.0 0.46 0.6573 1.0 1678372 ChemDiv1_004839 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L22 compound treatment 281.4 91.9 0.48 278.4 91.8 0.48 0.6764 1.0 1785229 ChemDiv1_004840 CCOc1ccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccc(C)cc4)c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L23 mock treatment 280.4 90.9 0.47 276.6 90.0 0.47 0.6661 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 L24 mock treatment 81.9 -108.0 -0.56 75.4 -111.0 -0.58 -0.8056 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M01 compound treatment 280.8 91.3 0.48 283.0 96.4 0.5 0.6911 0.9997 1430945 ChemDiv1_004841 OCCNc1nc2nonc2nc1Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M02 compound treatment 285.1 95.6 0.5 280.6 94.0 0.49 0.6982 0.9999 1702630 ChemDiv1_004842 COCc1cc(C)nc2sc(C(=O)c3ccccc3)c(NC(=O)c4ccccc4)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M03 compound treatment 292.1 103.0 0.54 290.7 104.0 0.54 0.7611 1.0 1972653 ChemDiv1_004843 CC(=O)/N=C\1/NC(=O)/C(=C/c2ccc(o2)c3ccc(F)cc3F)/S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M04 compound treatment 283.4 93.9 0.49 285.1 98.5 0.51 0.7084 0.9998 1972654 ChemDiv1_004844 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\3/C(=O)N(C)c4ccccc34)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M05 compound treatment 282.4 92.9 0.48 282.2 95.6 0.5 0.6941 0.9999 1155316 ChemDiv1_004845 COc1cc(ccc1OCc2ccc(F)cc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M06 compound treatment 278.9 89.4 0.47 283.7 97.1 0.5 0.6867 0.9992 1385987 ChemDiv1_004846 Brc1ccc(cc1)c2cn3ccc4ccccc4c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M07 compound treatment 280.0 90.5 0.47 283.5 96.9 0.5 0.69 0.9995 1544072 ChemDiv1_004847 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(nc5ccccc45)c6ccncc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M08 compound treatment 281.4 91.9 0.48 285.5 98.9 0.51 0.7025 0.9994 1972655 ChemDiv1_004848 Cc1cccc(NC2=NC(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/S2)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M09 compound treatment 283.2 93.7 0.49 282.6 96.0 0.5 0.6985 0.9999 1972656 ChemDiv1_004849 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M10 compound treatment 284.8 95.3 0.5 286.7 100.0 0.52 0.7195 0.9997 1972657 ChemDiv1_004850 COc1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C(=O)CCN4C(=O)\C(=C/c5cccs5)\SC4=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M11 compound treatment 283.6 94.1 0.49 279.6 93.0 0.48 0.6889 1.0 1972658 ChemDiv1_004851 Cc1cc(C)nc(Sc2nnc(C)c3ccccc23)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M12 compound treatment 281.4 91.9 0.48 280.7 94.1 0.49 0.6849 1.0 1923709 ChemDiv1_004852 Cc1nnc(NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M13 compound treatment 282.5 93.0 0.49 277.9 91.3 0.47 0.6786 0.9999 1450129 ChemDiv1_004853 Cc1cccc(OC(=O)CSc2nnc(C)c3ccccc23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M14 compound treatment 282.9 93.4 0.49 280.2 93.6 0.49 0.6886 1.0 1948374 ChemDiv1_004854 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCCCn4ccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M15 compound treatment 277.6 88.1 0.46 279.7 93.1 0.48 0.6672 0.9997 1972659 ChemDiv1_004855 CCSc1nnc(c2ccc(C)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M16 compound treatment 280.7 91.2 0.48 278.6 92.0 0.48 0.6746 1.0 1785232 ChemDiv1_004856 Cc1sc2nc(SCC(=O)N3CCN(CCO)CC3)[nH]c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M17 compound treatment 305.2 116.0 0.6 303.7 117.0 0.61 0.8572 1.0 1972660 ChemDiv1_004857 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(cc3OC)N(CC)CC)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M18 compound treatment 279.0 89.5 0.47 276.3 89.7 0.47 0.6598 1.0 1647899 ChemDiv1_004858 CC(C)CCSc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(=C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M19 compound treatment 275.8 86.3 0.45 275.5 88.9 0.46 0.6451 0.9999 1972661 ChemDiv1_004859 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)c(C)n1c4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M20 compound treatment 280.9 91.4 0.48 280.2 93.6 0.49 0.6812 0.9999 1972662 ChemDiv1_004860 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-])cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M21 compound treatment 284.3 94.8 0.49 277.9 91.3 0.47 0.6853 0.9998 1972663 ChemDiv1_004861 COc1cc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)ccc1OCc4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M22 compound treatment 276.4 86.9 0.45 274.5 87.9 0.46 0.6436 1.0 1725655 ChemDiv1_004862 CS(=O)(=O)c1ccc2nc(NC(=O)CN3C(=O)CCC3=O)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M23 mock treatment 283.5 94.0 0.49 275.3 88.7 0.46 0.6728 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 M24 mock treatment 193.4 3.91 0.02 186.3 -0.309 0.0 0.0133 0.6494 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N01 compound treatment 289.2 99.7 0.52 288.3 102.0 0.53 0.7416 1.0 1350036 ChemDiv1_004863 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N02 compound treatment 285.5 96.0 0.5 281.9 95.3 0.5 0.7044 1.0 1242815 ChemDiv1_004864 Cc1cc(C)nc(NC(c2ccco2)c3ccc4cccnc4c3O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N03 compound treatment 285.5 96.0 0.5 282.5 95.9 0.5 0.7066 1.0 1149633 ChemDiv1_004865 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2c3CSCc3nn2c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N04 compound treatment 281.7 92.2 0.48 279.9 93.3 0.48 0.683 1.0 1948325 ChemDiv1_004866 Clc1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N05 compound treatment 283.8 94.3 0.49 280.4 93.8 0.49 0.6926 1.0 1675405 ChemDiv1_004867 COc1ccc(cc1)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N06 compound treatment 278.4 88.9 0.46 279.9 93.3 0.48 0.6709 0.9998 1972664 ChemDiv1_004868 OCCN1CCN(CC1)C(c2ccc(cc2)C(F)(F)F)c3ccc4cccnc4c3O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N07 compound treatment 278.0 88.5 0.46 289.3 103.0 0.53 0.7039 0.9974 1125763 ChemDiv1_004869 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(OC)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N08 compound treatment 280.5 91.0 0.47 280.5 93.9 0.49 0.6808 0.9999 1972665 ChemDiv1_004870 O=C(CSc1nnc2ccccn12)NCc3ccco3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N09 compound treatment 282.3 92.8 0.48 282.0 95.4 0.5 0.693 0.9999 1972666 ChemDiv1_004871 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(cc3)[N+](=O)[O-])c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N10 compound treatment 278.9 89.4 0.47 280.1 93.5 0.49 0.6734 0.9998 1949865 ChemDiv1_004872 Cc1sc2nc(SCC(=O)NCc3cccnc3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N11 compound treatment 284.2 94.7 0.49 279.7 93.1 0.48 0.6915 0.9999 1944642 ChemDiv1_004873 COc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)OCc3ccccc3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N12 compound treatment 280.7 91.2 0.48 278.7 92.1 0.48 0.6749 1.0 1486916 ChemDiv1_004874 O=C1C2C3CC(C=C3)C2C(=O)N1CCN4CCN(CC4)S(=O)(=O)c5ccc6ccccc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N13 compound treatment 278.7 89.2 0.47 282.4 95.8 0.5 0.6812 0.9994 1572127 ChemDiv1_004875 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(Cl)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N14 compound treatment 281.9 92.4 0.48 282.9 96.3 0.5 0.6948 0.9998 1951731 ChemDiv1_004876 Cc1sc2nc(SCC(=O)N3CCOCC3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N15 compound treatment 282.9 93.4 0.49 278.5 91.9 0.48 0.6823 1.0 1436157 ChemDiv1_004877 CSc1nc2ccc(NC(=O)CN3C(=O)c4ccccc4C3=O)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N16 compound treatment 279.2 89.7 0.47 275.4 88.8 0.46 0.6573 1.0 1941313 ChemDiv1_004878 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCN6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N17 compound treatment 277.4 87.9 0.46 277.6 91.0 0.47 0.6587 0.9999 1972667 ChemDiv1_004879 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N18 compound treatment 276.0 86.5 0.45 281.3 94.7 0.49 0.6672 0.9991 1972668 ChemDiv1_004880 OC(=O)CCCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N19 compound treatment 279.4 89.9 0.47 276.8 90.2 0.47 0.6632 1.0 1940006 ChemDiv1_004881 Cc1c(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N20 compound treatment 277.8 88.3 0.46 280.7 94.1 0.49 0.6716 0.9996 1731664 ChemDiv1_004882 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N21 compound treatment 278.8 89.3 0.47 277.7 91.1 0.47 0.6643 1.0 1945143 ChemDiv1_004883 COC(=O)c1ccc(CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N22 compound treatment 280.4 90.9 0.47 275.2 88.6 0.46 0.661 0.9999 1972669 ChemDiv1_004884 COc1ccccc1C2CC(=NN2C(=O)CCCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N23 mock treatment 281.5 92.0 0.48 280.3 93.7 0.49 0.6838 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 N24 mock treatment 193.3 3.81 0.02 188.0 1.39 0.01 0.0192 0.9061 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O01 compound treatment 283.8 94.3 0.49 284.7 98.1 0.51 0.7084 0.9998 1535719 ChemDiv1_004885 Cc1ccc(Nc2nc3nonc3nc2NC4C5CC6CC(C5)CC4C6)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O02 compound treatment 282.5 93.0 0.49 285.7 99.1 0.52 0.7073 0.9996 1528553 ChemDiv1_004886 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)sc4CC(C)CCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O03 compound treatment 283.8 94.3 0.49 284.6 98.0 0.51 0.7081 0.9998 1343072 ChemDiv1_004887 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(F)cc4F)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O04 compound treatment 293.4 104.0 0.54 287.3 101.0 0.52 0.7534 0.9998 1972670 ChemDiv1_004888 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\c3ccc(OC)c(OC)c3)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O05 compound treatment 281.9 92.4 0.48 277.1 90.5 0.47 0.6735 0.9999 1633492 ChemDiv1_004889 CCOC(=O)c1ccc(Nc2nc3nonc3nc2N(CC)CC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O06 compound treatment 280.8 91.3 0.48 280.4 93.8 0.49 0.6816 0.9999 1972671 ChemDiv1_004890 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O07 compound treatment 280.1 90.6 0.47 278.4 91.8 0.48 0.6716 1.0 1972672 ChemDiv1_004891 Clc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O08 compound treatment 286.2 96.7 0.5 280.9 94.3 0.49 0.7033 0.9999 1972673 ChemDiv1_004892 COc1ccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O09 compound treatment 280.4 90.9 0.47 279.8 93.2 0.48 0.6779 0.9999 1972674 ChemDiv1_004893 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nn3c(nc4ccccc4c3=O)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O10 compound treatment 302.4 113.0 0.59 298.9 112.0 0.58 0.8292 1.0 1972675 ChemDiv1_004894 O=C(CCN1C(=O)/C(=C\c2cccs2)/SC1=S)N3c4ccccc4Sc5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O11 compound treatment 281.7 92.2 0.48 279.7 93.1 0.48 0.6823 1.0 1972676 ChemDiv1_004895 Cc1nnc(SCC(=O)N)c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O12 compound treatment 283.1 93.6 0.49 284.9 98.3 0.51 0.7066 0.9997 1972677 ChemDiv1_004896 COc1ccccc1NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O13 compound treatment 280.8 91.3 0.48 276.6 90.0 0.47 0.6676 1.0 1719439 ChemDiv1_004897 Cc1nn(CC(=O)Nc2ccc(Cl)cc2Cl)c(=O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O14 compound treatment 278.1 88.6 0.46 279.7 93.1 0.48 0.669 0.9997 1947764 ChemDiv1_004898 Cc1sc2nc(SCC(=O)NCCCn3ccnc3)[nH]c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O15 compound treatment 284.8 95.3 0.5 279.0 92.4 0.48 0.6912 0.9998 1946934 ChemDiv1_004899 CCSc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O16 compound treatment 279.1 89.6 0.47 276.3 89.7 0.47 0.6602 1.0 1948644 ChemDiv1_004900 CCOC(=O)CSc1nnc(c2cccc(OC)c2)n1c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O17 compound treatment 345.3 156.0 0.81 348.3 162.0 0.84 1.169 0.9999 1972678 ChemDiv1_004901 OC(=O)c1ccccc1c2ccc(/C=C\3/C(=O)NC(=S)N(C3=O)c4ccc(Br)cc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O18 compound treatment 281.3 91.8 0.48 277.8 91.2 0.47 0.6738 1.0 1280842 ChemDiv1_004902 COc1ccccc1C2=NN(C(C2)c3ccccc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O19 compound treatment 276.9 87.4 0.46 276.5 89.9 0.47 0.6528 0.9999 1972679 ChemDiv1_004903 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)c(C)n1c4cccc(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O20 compound treatment 276.0 86.5 0.45 281.6 95.0 0.49 0.6683 0.999 1972680 ChemDiv1_004904 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4c(C)onc4c5ccccc5Cl)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O21 compound treatment 280.5 91.0 0.47 276.3 89.7 0.47 0.6654 1.0 1972681 ChemDiv1_004905 COc1ccc(cc1)N2C(=O)/C(=C\c3ccc(o3)c4ccccc4[N+](=O)[O-])/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O22 compound treatment 277.8 88.3 0.46 275.0 88.4 0.46 0.6506 1.0 1972682 ChemDiv1_004906 [O-][N+](=O)c1ccc2sc(cc2c1)C(=O)Nc3ccc(Br)cc3C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O23 mock treatment 276.5 87.0 0.45 275.5 88.9 0.46 0.6477 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 O24 mock treatment 121.1 -68.4 -0.36 93.5 -93.1 -0.48 -0.5945 -0.9887 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P01 compound treatment 284.7 95.2 0.5 280.0 93.4 0.49 0.6945 0.9999 1450296 ChemDiv1_004907 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P02 compound treatment 283.5 94.0 0.49 281.1 94.5 0.49 0.6941 1.0 1560844 ChemDiv1_004908 Clc1c(sc2ccccc12)C(=O)Nc3nc(cs3)c4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P03 compound treatment 284.2 94.7 0.49 282.0 95.4 0.5 0.7 1.0 1740134 ChemDiv1_004909 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P04 compound treatment 285.5 96.0 0.5 280.6 94.0 0.49 0.6996 0.9999 1972683 ChemDiv1_004910 O=C(/C=C/c1ccc2OCOc2c1)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P05 compound treatment 283.5 94.0 0.49 284.5 97.9 0.51 0.7066 0.9998 1128943 ChemDiv1_004911 COc1ccc(cc1)C2=NN(C(C2)c3cc4ccc(C)cc4nc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P06 compound treatment 281.8 92.3 0.48 282.8 96.2 0.5 0.6941 0.9998 1366639 ChemDiv1_004912 Fc1ccc(cc1)c2csc3ncnc(NCCc4ccc5OCOc5c4)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P07 compound treatment 280.2 90.7 0.47 277.8 91.2 0.47 0.6698 1.0 1972684 ChemDiv1_004913 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)OC)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P08 compound treatment 288.0 98.5 0.51 289.9 103.0 0.54 0.743 0.9998 1972685 ChemDiv1_004914 COc1ccc(cc1OC)c2csc3[nH]c(=S)n(CC=C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P09 compound treatment 273.2 83.7 0.44 279.0 92.4 0.48 0.6484 0.9989 1737154 ChemDiv1_004915 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(Br)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P10 compound treatment 276.0 86.5 0.45 280.7 94.1 0.49 0.665 0.9992 1941283 ChemDiv1_004916 OCCCNC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P11 compound treatment 280.4 90.9 0.47 277.2 90.6 0.47 0.6683 1.0 1972686 ChemDiv1_004917 [O-][N+](=O)c1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P12 compound treatment 281.6 92.1 0.48 278.4 91.8 0.48 0.6772 1.0 1972687 ChemDiv1_004918 O=C1C2C3CC(C=C3)C2C(=O)N1CCN4CCN(CC4)S(=O)(=O)/C=C\c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P13 compound treatment 276.7 87.2 0.45 278.4 91.8 0.48 0.6591 0.9997 1873279 ChemDiv1_004919 CCCOC(=O)CSC1=C(C#N)C(C(C(=O)OC)C(=O)N1)c2ccc(Cl)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P14 compound treatment 279.4 89.9 0.47 279.6 93.0 0.48 0.6735 0.9999 1310399 ChemDiv1_004920 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P15 compound treatment 281.0 91.5 0.48 283.7 97.1 0.5 0.6944 0.9996 1972688 ChemDiv1_004921 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)CN3C(=O)c4ccccc4C3=O)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P16 compound treatment 277.2 87.7 0.46 279.3 92.7 0.48 0.6642 0.9997 1924339 ChemDiv1_004922 CCCCN(CCCC)C(=O)CSc1nc2sc(C)c(C)c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P17 compound treatment 281.8 92.3 0.48 281.9 95.3 0.5 0.6908 0.9999 1670644 ChemDiv1_004923 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5[nH]4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P18 compound treatment 274.8 85.3 0.45 281.1 94.5 0.49 0.662 0.9988 1591656 ChemDiv1_004924 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P19 compound treatment 279.1 89.6 0.47 281.6 95.0 0.49 0.6797 0.9996 1379692 ChemDiv1_004925 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P20 compound treatment 281.9 92.4 0.48 285.6 99.0 0.51 0.7047 0.9995 1518000 ChemDiv1_004926 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P21 compound treatment 277.8 88.3 0.46 282.3 95.7 0.5 0.6775 0.9993 1155193 ChemDiv1_004927 OCCN(CCO)C(=O)CSc1nc2sc3CCCCc3c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P22 compound treatment 283.0 93.5 0.49 275.0 88.4 0.46 0.6698 0.9996 1972689 ChemDiv1_004928 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P23 mock treatment 284.6 95.1 0.5 280.2 93.6 0.49 0.6948 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.600 P24 mock treatment 95.7 -93.8 -0.49 97.8 -88.8 -0.46 -0.6724 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A01 compound treatment 285.3 96.6 0.5 286.3 100.0 0.52 0.7239 0.9999 1729876 ChemDiv1_004929 CCOc1ccc2cc(C3CC(=NN3C(=O)C)c4ccccc4)c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A02 compound treatment 283.4 94.7 0.49 286.5 100.0 0.52 0.7176 0.9997 1742286 ChemDiv1_004930 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OCc4ccccc4)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A03 compound treatment 281.4 92.7 0.48 284.1 97.8 0.51 0.7014 0.9997 1446629 ChemDiv1_004931 Cn1c(=O)n(C)c2nc(N3CCCCC3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A04 compound treatment 279.7 91.0 0.47 282.7 96.4 0.5 0.69 0.9996 1319177 ChemDiv1_004932 CC1=C(C(c2ccc(OCc3ccccc3)cc2)n4nnnc4N1)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A05 compound treatment 283.7 95.0 0.5 282.3 96.0 0.5 0.7033 1.0 1972690 ChemDiv1_004933 Cc1cccc2cc(CC3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(=O)[nH]c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A06 compound treatment 282.4 93.7 0.49 278.5 92.2 0.48 0.6845 0.9999 1338932 ChemDiv1_004934 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A07 compound treatment 287.5 98.8 0.52 288.1 102.0 0.53 0.7386 0.9999 1639329 ChemDiv1_004935 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A08 compound treatment 278.9 90.2 0.47 281.0 94.7 0.49 0.6808 0.9998 1508865 ChemDiv1_004936 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4sc(C)nc4c3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A09 compound treatment 282.8 94.1 0.49 281.7 95.4 0.5 0.6978 1.0 1972691 ChemDiv1_004937 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A10 compound treatment 276.7 88.0 0.46 276.6 90.3 0.47 0.6565 0.9999 1697271 ChemDiv1_004938 O=C(Nc1nc-2c(CCc3ccccc23)s1)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A11 compound treatment 279.6 90.9 0.47 280.3 94.0 0.49 0.6808 0.9999 1555460 ChemDiv1_004939 CCOc1ccc(NC(=O)Nc2nc(cs2)c3ccc(Oc4ccccc4)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A12 compound treatment 279.1 90.4 0.47 279.7 93.4 0.49 0.6768 0.9999 1972692 ChemDiv1_004940 Clc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4)C(=O)CN5CCOCC5)c(c6ccccc6)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A13 compound treatment 277.6 88.9 0.46 279.3 93.0 0.48 0.6698 0.9998 1972693 ChemDiv1_004941 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A14 compound treatment 278.4 89.7 0.47 280.2 93.9 0.49 0.676 0.9998 1646534 ChemDiv1_004942 CSc1nc2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A15 compound treatment 279.1 90.4 0.47 275.5 89.2 0.46 0.6613 1.0 1372115 ChemDiv1_004943 COc1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A16 compound treatment 276.3 87.6 0.46 277.7 91.4 0.47 0.6591 0.9998 1354587 ChemDiv1_004944 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A17 compound treatment 279.5 90.8 0.47 281.5 95.2 0.49 0.6849 0.9998 1349292 ChemDiv1_004945 COc1ccc(OC)c(c1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A18 compound treatment 277.0 88.3 0.46 280.4 94.1 0.49 0.6716 0.9996 1972694 ChemDiv1_004946 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccs3)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A19 compound treatment 276.6 87.9 0.46 275.8 89.5 0.47 0.6532 1.0 1344207 ChemDiv1_004947 COc1ccc(OC)c(c1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A20 compound treatment 277.1 88.4 0.46 280.0 93.7 0.49 0.6705 0.9996 1972695 ChemDiv1_004948 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccc(c3)[N+](=O)[O-])c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A21 compound treatment 278.0 89.3 0.47 281.7 95.4 0.5 0.6801 0.9995 1874356 ChemDiv1_004949 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cccc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A22 compound treatment 278.3 89.6 0.47 274.6 88.3 0.46 0.6551 1.0 1549475 ChemDiv1_004950 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cccc(Br)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A23 mock treatment 274.7 86.0 0.45 275.2 88.9 0.46 0.644 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 A24 mock treatment 82.8 -106.0 -0.55 76.6 -110.0 -0.57 -0.7938 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B01 compound treatment 280.1 91.4 0.48 281.7 95.4 0.5 0.6878 0.9998 1592111 ChemDiv1_004951 CC1=C(C(c2ccccn2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B02 compound treatment 281.9 93.2 0.49 281.9 95.6 0.5 0.6952 0.9999 1608435 ChemDiv1_004952 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(Br)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B03 compound treatment 285.8 97.1 0.51 281.6 95.3 0.5 0.7085 0.9999 1636130 ChemDiv1_004953 CC1=C(C(c2ccc3OCOc3c2)n4ncnc4N1)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B04 compound treatment 286.8 98.1 0.51 279.1 92.8 0.48 0.703 0.9996 1265027 ChemDiv1_004954 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc(cs3)c4cc5ccccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B05 compound treatment 284.1 95.4 0.5 284.6 98.3 0.51 0.7132 0.9999 1265414 ChemDiv1_004955 Cc1ccccc1n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B06 compound treatment 286.1 97.4 0.51 288.7 102.0 0.53 0.7357 0.9997 1178364 ChemDiv1_004956 NC(=O)c1oc2ccccc2c1NC(=O)c3cc(nc4ccccc34)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B07 compound treatment 278.4 89.7 0.47 279.7 93.4 0.49 0.6742 0.9998 1195190 ChemDiv1_004957 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B08 compound treatment 279.7 91.0 0.47 283.8 97.5 0.51 0.6941 0.9995 1972696 ChemDiv1_004958 OC(COc1ccc(Cl)cc1)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B09 compound treatment 280.4 91.7 0.48 282.0 95.7 0.5 0.69 0.9998 1493865 ChemDiv1_004959 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B10 compound treatment 276.6 87.9 0.46 282.7 96.4 0.5 0.6786 0.999 1972697 ChemDiv1_004960 COc1cccc(OC)c1OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B11 compound treatment 282.1 93.4 0.49 280.0 93.7 0.49 0.6889 1.0 1420229 ChemDiv1_004961 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B12 compound treatment 279.2 90.5 0.47 278.9 92.6 0.48 0.6742 1.0 1972698 ChemDiv1_004962 O=C1N(CC2CCN(CC2)S(=O)(=O)/C=C/c3ccccc3)C(=O)c4cccc5cccc1c45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B13 compound treatment 279.0 90.3 0.47 280.6 94.3 0.49 0.6797 0.9998 1924867 ChemDiv1_004963 COc1ccc2c(Cl)c(sc2c1)C(=O)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B14 compound treatment 278.2 89.5 0.47 280.7 94.4 0.49 0.6771 0.9997 1972699 ChemDiv1_004964 CCOC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)scc1c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B15 compound treatment 277.7 89.0 0.46 275.2 88.9 0.46 0.6551 1.0 1972700 ChemDiv1_004965 CCOC(=O)c1c(C)oc2cc(Br)c(OC/C=C/c3ccccc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B16 compound treatment 279.8 91.1 0.48 278.6 92.3 0.48 0.6753 1.0 1972701 ChemDiv1_004966 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC6CC7CC(C6)C5)C7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B17 compound treatment 280.5 91.8 0.48 277.3 91.0 0.47 0.6731 1.0 1195179 ChemDiv1_004967 COC(=O)c1c(C)oc2cc(Br)c(OCc3c(F)cccc3Cl)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B18 compound treatment 281.0 92.3 0.48 280.1 93.8 0.49 0.6852 1.0 1972702 ChemDiv1_004968 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc(cc3)[N+](=O)[O-])c(NC4CCCCC4)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B19 compound treatment 275.4 86.7 0.45 277.8 91.5 0.48 0.6561 0.9997 1972703 ChemDiv1_004969 CCOC(=O)CSc1nnc(CSc2nc3sc4CCCc4c3c(=O)[nH]2)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B20 compound treatment 278.4 89.7 0.47 279.5 93.2 0.48 0.6734 0.9999 1531948 ChemDiv1_004970 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1CC(O)COc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B21 compound treatment 277.1 88.4 0.46 277.9 91.6 0.48 0.6628 0.9999 1176170 ChemDiv1_004971 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B22 compound treatment 279.8 91.1 0.48 274.4 88.1 0.46 0.6599 0.9998 1728356 ChemDiv1_004972 Cc1cc(C)c(NC(=O)Cn2c3ccccc3c4nc5ccccc5nc24)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B23 mock treatment 279.9 91.2 0.48 275.6 89.3 0.46 0.6646 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 B24 mock treatment 78.4 -110.0 -0.58 78.4 -108.0 -0.56 -0.8034 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C01 compound treatment 283.5 94.8 0.49 284.8 98.5 0.51 0.7117 0.9999 1163610 ChemDiv1_004973 CCOc1ccc2cc(C3CC(=NN3C(=O)C)c4ccc(C)cc4)c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C02 compound treatment 284.0 95.3 0.5 280.6 94.3 0.49 0.6981 1.0 1625743 ChemDiv1_004974 CC1=C(C(c2ccccc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C03 compound treatment 279.4 90.7 0.47 282.4 96.1 0.5 0.6878 0.9996 1596638 ChemDiv1_004975 Cn1c(=O)n(C)c2nc(N3CCOCC3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C04 compound treatment 283.6 94.9 0.5 278.2 91.9 0.48 0.6879 0.9998 1233417 ChemDiv1_004976 CC1=C(C(c2ccc(OC(=O)c3ccccc3)cc2)n4nnnc4N1)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C05 compound treatment 275.9 87.2 0.46 280.6 94.3 0.49 0.6683 0.9993 1400572 ChemDiv1_004977 CCC(=O)N1N=C(CC1Cc2cc3cccc(C)c3[nH]c2=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C06 compound treatment 281.9 93.2 0.49 284.1 97.8 0.51 0.7033 0.9998 1972704 ChemDiv1_004978 CC1=C(C(c2ccc(cc2)[N+](=O)[O-])n3nnnc3N1)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C07 compound treatment 282.8 94.1 0.49 285.7 99.4 0.52 0.7125 0.9997 1489378 ChemDiv1_004979 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C08 compound treatment 281.6 92.9 0.48 281.5 95.2 0.49 0.6926 0.9999 1482919 ChemDiv1_004980 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCCC5)sc32)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C09 compound treatment 286.6 97.9 0.51 290.5 104.0 0.54 0.7441 0.9996 1972705 ChemDiv1_004981 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C10 compound treatment 274.5 85.8 0.45 282.5 96.2 0.5 0.6701 0.9985 1972706 ChemDiv1_004982 O=C(Nc1ccc2C(=O)c3ccccc3C(=O)c2c1)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C11 compound treatment 280.7 92.0 0.48 284.5 98.2 0.51 0.7003 0.9995 1742235 ChemDiv1_004983 COc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C12 compound treatment 279.2 90.5 0.47 280.3 94.0 0.49 0.6793 0.9999 1972707 ChemDiv1_004984 Clc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4Cl)C(=O)CN5CCOCC5)c(c6ccccc6)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C13 compound treatment 278.9 90.2 0.47 276.9 90.6 0.47 0.6657 1.0 1458516 ChemDiv1_004985 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C14 compound treatment 276.5 87.8 0.46 281.5 95.2 0.49 0.6738 0.9993 1565441 ChemDiv1_004986 CC1(C)CC(=O)c2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)nc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C15 compound treatment 277.9 89.2 0.47 277.7 91.4 0.47 0.665 0.9999 1469942 ChemDiv1_004987 COc1ccc(cc1OC)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C16 compound treatment 277.6 88.9 0.46 279.0 92.7 0.48 0.6687 0.9998 1220811 ChemDiv1_004988 CN(c1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5sc(C)nc5c4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C17 compound treatment 278.6 89.9 0.47 280.1 93.8 0.49 0.6764 0.9998 1371528 ChemDiv1_004989 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C18 compound treatment 281.4 92.7 0.48 278.2 91.9 0.48 0.6797 1.0 1302789 ChemDiv1_004990 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C19 compound treatment 280.6 91.9 0.48 280.4 94.1 0.49 0.6849 1.0 1686659 ChemDiv1_004991 CC1=C(C(c2ccc(Br)cc2)n3ncnc3N1)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C20 compound treatment 285.6 96.9 0.51 293.0 107.0 0.55 0.7496 0.9989 1972708 ChemDiv1_004992 CNC(=S)N1N=C(CC1c2ccc(cc2)N(C)C)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C21 compound treatment 278.8 90.1 0.47 273.7 87.4 0.45 0.6536 0.9999 1472593 ChemDiv1_004993 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C22 compound treatment 275.4 86.7 0.45 270.8 84.5 0.44 0.6304 0.9999 1287914 ChemDiv1_004994 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OCc4ccccc4)c(OCC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C23 mock treatment 279.1 90.4 0.47 282.4 96.1 0.5 0.6867 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 C24 mock treatment 86.6 -102.0 -0.53 76.9 -109.0 -0.57 -0.7787 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D01 compound treatment 285.1 96.4 0.5 284.3 98.0 0.51 0.7158 1.0 1123174 ChemDiv1_004995 CC1=C(C(c2cccc(Br)c2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D02 compound treatment 281.9 93.2 0.49 285.0 98.7 0.51 0.7066 0.9996 1972709 ChemDiv1_004996 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(cc4s3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D03 compound treatment 282.2 93.5 0.49 281.9 95.6 0.5 0.6963 1.0 1611784 ChemDiv1_004997 CC1=C(C(c2ccccn2)n3ncnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D04 compound treatment 282.8 94.1 0.49 282.0 95.7 0.5 0.6989 1.0 1972710 ChemDiv1_004998 CS(=O)(=O)c1ccc2nc(NC(=S)NC(=O)c3cc4cc(ccc4s3)[N+](=O)[O-])sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D05 compound treatment 285.9 97.2 0.51 283.2 96.9 0.5 0.7147 1.0 1249513 ChemDiv1_004999 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D06 compound treatment 276.8 88.1 0.46 282.7 96.4 0.5 0.6793 0.9991 1972711 ChemDiv1_005000 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D07 compound treatment 280.6 91.9 0.48 281.3 95.0 0.49 0.6882 0.9999 1972712 ChemDiv1_005001 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D08 compound treatment 280.2 91.5 0.48 283.9 97.6 0.51 0.6963 0.9995 1972713 ChemDiv1_005002 OC(COc1ccc2OCOc2c1)CN3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D09 compound treatment 282.0 93.3 0.49 278.4 92.1 0.48 0.6827 1.0 1704023 ChemDiv1_005003 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D10 compound treatment 276.4 87.7 0.46 278.8 92.5 0.48 0.6635 0.9997 1972714 ChemDiv1_005004 OC(COc1ccccc1F)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D11 compound treatment 284.4 95.7 0.5 286.3 100.0 0.52 0.7206 0.9998 1392853 ChemDiv1_005005 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D12 compound treatment 277.9 89.2 0.47 281.3 95.0 0.49 0.6782 0.9996 1972715 ChemDiv1_005006 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D13 compound treatment 278.4 89.7 0.47 281.3 95.0 0.49 0.6801 0.9996 1924918 ChemDiv1_005007 COc1ccc(/C=C/C(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D14 compound treatment 279.0 90.3 0.47 275.2 88.9 0.46 0.6599 1.0 1972716 ChemDiv1_005008 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc(Cl)c1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D15 compound treatment 277.0 88.3 0.46 279.1 92.8 0.48 0.6668 0.9997 1972717 ChemDiv1_005009 CCOC(=O)c1c(oc2cc(Br)c(OCC(=O)c3ccc(OC)cc3)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D16 compound treatment 281.9 93.2 0.49 279.7 93.4 0.49 0.6871 1.0 1972718 ChemDiv1_005010 CCOC(=O)c1c(NC(=O)CN2C(=O)c3cccc4cccc(C2=O)c34)sc5CCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D17 compound treatment 281.7 93.0 0.49 281.3 95.0 0.49 0.6922 1.0 1249548 ChemDiv1_005011 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D18 compound treatment 278.8 90.1 0.47 273.5 87.2 0.45 0.6529 0.9998 1972719 ChemDiv1_005012 COc1ccc(OCC(O)Cn2c(NCCCn3ccnc3)nc4n(C)c(=O)[nH]c(=O)c24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D19 compound treatment 275.1 86.4 0.45 273.6 87.3 0.45 0.6396 1.0 1281706 ChemDiv1_005013 C=CCn1c(SCC(=O)NCCN2CCOCC2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D20 compound treatment 279.6 90.9 0.47 278.2 91.9 0.48 0.6731 1.0 1496925 ChemDiv1_005014 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCCCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D21 compound treatment 280.5 91.8 0.48 276.2 89.9 0.47 0.6691 0.9999 1557814 ChemDiv1_005015 O=C(Nc1nc2ccccc2c3nc4ccccc4n13)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D22 compound treatment 278.6 89.9 0.47 279.8 93.5 0.49 0.6753 0.9998 1972720 ChemDiv1_005016 O=c1n(nc2-c3ccccc3-c4cccc1c42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D23 mock treatment 281.1 92.4 0.48 276.3 90.0 0.47 0.6716 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 D24 mock treatment 80.7 -108.0 -0.56 82.6 -104.0 -0.54 -0.7795 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E01 compound treatment 284.5 95.8 0.5 287.2 101.0 0.52 0.7243 0.9997 1600069 ChemDiv1_005017 CCOc1ccc2cc(C3CC(=NN3C(=O)CC)c4ccc(Br)cc4)c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E02 compound treatment 284.1 95.4 0.5 285.5 99.2 0.52 0.7165 0.9998 1643936 ChemDiv1_005018 CC1=C(C(c2ccc(Cl)cc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E03 compound treatment 285.9 97.2 0.51 283.0 96.7 0.5 0.714 1.0 1298851 ChemDiv1_005019 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E04 compound treatment 286.1 97.4 0.51 281.7 95.4 0.5 0.7099 0.9999 1393931 ChemDiv1_005020 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E05 compound treatment 278.2 89.5 0.47 282.6 96.3 0.5 0.6841 0.9994 1501606 ChemDiv1_005021 Cc1ccc(cc1)C2=NN(C(Cc3cc4cccc(C)c4nc3Cl)C2)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E06 compound treatment 282.4 93.7 0.49 286.5 100.0 0.52 0.7139 0.9995 1252430 ChemDiv1_005022 COc1ccc(cc1)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E07 compound treatment 302.5 114.0 0.59 314.1 128.0 0.66 0.8895 0.9984 1972721 ChemDiv1_005023 Cc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E08 compound treatment 284.6 95.9 0.5 280.4 94.1 0.49 0.6996 0.9999 1367218 ChemDiv1_005024 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5sc(C)nc5c4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E09 compound treatment 282.0 93.3 0.49 286.0 99.7 0.52 0.7106 0.9995 1972722 ChemDiv1_005025 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E10 compound treatment 281.3 92.6 0.48 280.0 93.7 0.49 0.686 1.0 1972723 ChemDiv1_005026 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E11 compound treatment 280.0 91.3 0.48 280.6 94.3 0.49 0.6834 0.9999 1203903 ChemDiv1_005027 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E12 compound treatment 281.7 93.0 0.49 281.6 95.3 0.5 0.6933 0.9999 1972724 ChemDiv1_005028 COc1ccccc1C2CC(=NN2C(=O)CN3CCOCC3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E13 compound treatment 282.4 93.7 0.49 283.4 97.1 0.5 0.7025 0.9999 1972725 ChemDiv1_005029 OC(=O)CCC(=O)N1N=C(CC1c2ccc(Br)cc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E14 compound treatment 280.7 92.0 0.48 281.2 94.9 0.49 0.6882 0.9999 1715807 ChemDiv1_005030 O=C(Nc1nc2CCCCc2s1)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E15 compound treatment 279.3 90.6 0.47 280.4 94.1 0.49 0.6801 0.9999 1139490 ChemDiv1_005031 COc1ccc(OC)c(c1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E16 compound treatment 276.7 88.0 0.46 283.1 96.8 0.5 0.6804 0.999 1972726 ChemDiv1_005032 COCCN(CCOC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4sc(C)nc4c3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E17 compound treatment 280.7 92.0 0.48 279.9 93.6 0.49 0.6834 1.0 1274051 ChemDiv1_005033 CC1=C(C(c2ccc(OCc3ccccc3)cc2)n4ncnc4N1)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E18 compound treatment 281.4 92.7 0.48 280.1 93.8 0.49 0.6867 1.0 1603959 ChemDiv1_005034 Clc1ccccc1C2CC(=NN2C(=O)c3cccs3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E19 compound treatment 280.3 91.6 0.48 279.1 92.8 0.48 0.679 1.0 1221179 ChemDiv1_005035 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E20 compound treatment 274.6 85.9 0.45 273.9 87.6 0.46 0.6388 1.0 1972727 ChemDiv1_005036 CC(=O)N1N=C(CC1c2ccc(Cl)cc2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E21 compound treatment 280.4 91.7 0.48 274.6 88.3 0.46 0.6628 0.9998 1655176 ChemDiv1_005037 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E22 compound treatment 280.8 92.1 0.48 275.5 89.2 0.46 0.6676 0.9998 1685741 ChemDiv1_005038 CC1=C(C(c2cccc(Br)c2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E23 mock treatment 284.2 95.5 0.5 275.1 88.8 0.46 0.6787 0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 E24 mock treatment 82.2 -106.0 -0.56 85.5 -101.0 -0.52 -0.7633 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F01 compound treatment 285.4 96.7 0.5 284.8 98.5 0.51 0.7188 1.0 1237430 ChemDiv1_005039 CC1=C(C(c2ccc(O)cc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F02 compound treatment 280.0 91.3 0.48 284.0 97.7 0.51 0.6959 0.9995 1404506 ChemDiv1_005040 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5ccccc5c4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F03 compound treatment 285.1 96.4 0.5 279.8 93.5 0.49 0.6993 0.9998 1737492 ChemDiv1_005041 CC1=C(C(c2ccc(O)cc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F04 compound treatment 280.6 91.9 0.48 285.0 98.7 0.51 0.7018 0.9994 1584826 ChemDiv1_005042 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(cc5CCc6cccc4c65)s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F05 compound treatment 283.1 94.4 0.49 279.1 92.8 0.48 0.6893 0.9999 1972728 ChemDiv1_005043 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F06 compound treatment 286.7 98.0 0.51 287.6 101.0 0.53 0.7338 0.9999 1637874 ChemDiv1_005044 O=C(CSc1nc(cc(c2ccco2)c1C#N)C3CC3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F07 compound treatment 286.7 98.0 0.51 284.9 98.6 0.51 0.7239 1.0 1365371 ChemDiv1_005045 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(Oc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F08 compound treatment 279.2 90.5 0.47 282.5 96.2 0.5 0.6874 0.9996 1972729 ChemDiv1_005046 OC(COCc1ccc2OCOc2c1)CN3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F09 compound treatment 281.6 92.9 0.48 280.8 94.5 0.49 0.69 1.0 1709532 ChemDiv1_005047 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)C5CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F10 compound treatment 277.1 88.4 0.46 283.4 97.1 0.5 0.683 0.999 1972730 ChemDiv1_005048 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F11 compound treatment 287.1 98.4 0.51 292.3 106.0 0.55 0.7526 0.9994 1418066 ChemDiv1_005049 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F12 compound treatment 281.3 92.6 0.48 278.9 92.6 0.48 0.6819 1.0 1972731 ChemDiv1_005050 CS(=O)(=O)c1ccc2nc(NC(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F13 compound treatment 281.6 92.9 0.48 281.4 95.1 0.49 0.6922 1.0 1925306 ChemDiv1_005051 O=C(/C=C/c1ccc2OCOc2c1)N3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F14 compound treatment 277.0 88.3 0.46 280.8 94.5 0.49 0.6731 0.9995 1972732 ChemDiv1_005052 COC(=O)c1ccc(cc1)n2c(C)cc(C(=O)CSc3nnc4sc5ccccc5n34)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F15 compound treatment 278.2 89.5 0.47 277.3 91.0 0.47 0.6646 1.0 1233222 ChemDiv1_005053 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3ccc(Cl)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F16 compound treatment 276.6 87.9 0.46 273.3 87.0 0.45 0.644 1.0 1972733 ChemDiv1_005054 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC5)S(=O)(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F17 compound treatment 278.1 89.4 0.47 279.2 92.9 0.48 0.6712 0.9999 1924928 ChemDiv1_005055 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6cccnc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F18 compound treatment 283.5 94.8 0.49 272.7 86.4 0.45 0.6673 0.9988 1300937 ChemDiv1_005056 COc1ccc(OCC(O)Cn2c(NCc3ccco3)nc4n(C)c(=O)[nH]c(=O)c24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F19 compound treatment 278.0 89.3 0.47 278.8 92.5 0.48 0.6694 0.9999 1917640 ChemDiv1_005057 CCOC(=O)CSc1nnc(Nc2ccc(Cl)cc2)n1c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F20 compound treatment 278.4 89.7 0.47 275.6 89.3 0.46 0.6591 1.0 1622264 ChemDiv1_005058 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCNCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F21 compound treatment 277.5 88.8 0.46 277.4 91.1 0.47 0.6624 0.9999 1126899 ChemDiv1_005059 O=C(Nc1nc2ccccc2c3nc4ccccc4n13)c5ccc(cc5)S(=O)(=O)N6CCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F22 compound treatment 280.2 91.5 0.48 273.7 87.4 0.45 0.6588 0.9997 1261533 ChemDiv1_005060 CCN(CC)CCn1c2ccccc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F23 mock treatment 280.4 91.7 0.48 277.6 91.3 0.47 0.6738 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 F24 mock treatment 76.1 -113.0 -0.59 77.6 -109.0 -0.57 -0.8149 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G01 compound treatment 282.7 94.0 0.49 286.1 99.8 0.52 0.7136 0.9996 1972734 ChemDiv1_005061 COC(=O)c1ccccc1NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G02 compound treatment 289.3 101.0 0.52 282.5 96.2 0.5 0.7247 0.9997 1391811 ChemDiv1_005062 CC1=C(C(c2ccccc2Cl)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G03 compound treatment 283.6 94.9 0.5 281.8 95.5 0.5 0.7011 1.0 1416557 ChemDiv1_005063 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2CC(O)COc4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G04 compound treatment 280.9 92.2 0.48 280.1 93.8 0.49 0.6849 1.0 1492206 ChemDiv1_005064 CC1=C(C(c2ccccc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G05 compound treatment 284.7 96.0 0.5 279.5 93.2 0.48 0.6967 0.9999 1618081 ChemDiv1_005065 COc1ccc(cc1)C2=NN(C(Cc3cc4cccc(C)c4nc3Cl)C2)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G06 compound treatment 282.3 93.6 0.49 285.6 99.3 0.52 0.7103 0.9996 1563220 ChemDiv1_005066 COc1ccc(cc1OC)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G07 compound treatment 291.7 103.0 0.54 293.2 107.0 0.56 0.7729 0.9999 1665643 ChemDiv1_005067 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3cccs3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G08 compound treatment 282.8 94.1 0.49 281.8 95.5 0.5 0.6981 1.0 1180794 ChemDiv1_005068 COc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G09 compound treatment 290.2 102.0 0.53 290.7 104.0 0.54 0.7581 0.9999 1972735 ChemDiv1_005069 Cc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G10 compound treatment 277.9 89.2 0.47 281.5 95.2 0.49 0.679 0.9995 1972736 ChemDiv1_005070 COc1ccccc1C2CC(=NN2C(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G11 compound treatment 287.9 99.2 0.52 286.3 100.0 0.52 0.7335 1.0 1972737 ChemDiv1_005071 [O-][N+](=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G12 compound treatment 277.6 88.9 0.46 281.1 94.8 0.49 0.6764 0.9995 1972738 ChemDiv1_005072 CN1CCN(CC(=O)N2N=C(CC2c3ccccc3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G13 compound treatment 283.4 94.7 0.49 278.3 92.0 0.48 0.6875 0.9999 1456998 ChemDiv1_005073 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G14 compound treatment 279.5 90.8 0.47 278.0 91.7 0.48 0.672 1.0 1639444 ChemDiv1_005074 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G15 compound treatment 278.7 90.0 0.47 278.2 91.9 0.48 0.6698 1.0 1268689 ChemDiv1_005075 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G16 compound treatment 279.5 90.8 0.47 282.9 96.6 0.5 0.69 0.9996 1972739 ChemDiv1_005076 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G17 compound treatment 281.6 92.9 0.48 277.8 91.5 0.48 0.679 1.0 1226788 ChemDiv1_005077 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G18 compound treatment 275.0 86.3 0.45 278.7 92.4 0.48 0.658 0.9995 1972740 ChemDiv1_005078 Brc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccco4)C(=O)c5ccco5)c(c6ccccc6)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G19 compound treatment 278.5 89.8 0.47 280.3 94.0 0.49 0.6768 0.9998 1139032 ChemDiv1_005079 COC(=O)C1=C(C)Nc2nnnn2C1c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G20 compound treatment 279.0 90.3 0.47 278.1 91.8 0.48 0.6705 1.0 1972741 ChemDiv1_005080 CC(=O)C1=C(C)Nc2ncnn2C1c3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G21 compound treatment 281.0 92.3 0.48 276.6 90.3 0.47 0.6724 0.9999 1274882 ChemDiv1_005081 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G22 compound treatment 274.2 85.5 0.45 273.4 87.1 0.45 0.6355 1.0 1518613 ChemDiv1_005082 CC1=C(C(c2ccc(O)cc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G23 mock treatment 280.2 91.5 0.48 278.9 92.6 0.48 0.6779 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 G24 mock treatment 83.3 -105.0 -0.55 84.0 -102.0 -0.53 -0.7648 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H01 compound treatment 280.2 91.5 0.48 283.5 97.2 0.51 0.6948 0.9996 1585954 ChemDiv1_005083 CCOc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H02 compound treatment 281.5 92.8 0.48 285.5 99.2 0.52 0.7069 0.9995 1566677 ChemDiv1_005084 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4CCC(C)Cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H03 compound treatment 283.7 95.0 0.5 286.4 100.0 0.52 0.7184 0.9997 1278854 ChemDiv1_005085 CCOc1cc(ccc1OCc2ccccc2)C3NC(=O)NC(=C3C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H04 compound treatment 281.7 93.0 0.49 285.7 99.4 0.52 0.7084 0.9995 1566033 ChemDiv1_005086 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H05 compound treatment 283.7 95.0 0.5 283.6 97.3 0.51 0.7081 1.0 1237224 ChemDiv1_005087 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H06 compound treatment 278.5 89.8 0.47 283.7 97.4 0.51 0.6893 0.9993 1136575 ChemDiv1_005088 CCOC(=O)C(C)Oc1ccc2c(=O)c(c(C)oc2c1)c3ccc4OCCCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H07 compound treatment 285.7 97.0 0.51 281.9 95.6 0.5 0.7092 1.0 1608019 ChemDiv1_005089 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H08 compound treatment 279.8 91.1 0.48 281.8 95.5 0.5 0.6871 0.9998 1972742 ChemDiv1_005090 COc1ccc(COCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H09 compound treatment 280.5 91.8 0.48 283.3 97.0 0.5 0.6952 0.9997 1972743 ChemDiv1_005091 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)c5ccc(cc5)S(=O)(=O)N6CCc7ccccc67 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H10 compound treatment 280.0 91.3 0.48 280.4 94.1 0.49 0.6827 0.9999 1972744 ChemDiv1_005092 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H11 compound treatment 281.8 93.1 0.49 283.3 97.0 0.5 0.7 0.9998 1658546 ChemDiv1_005093 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc6C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H12 compound treatment 278.6 89.9 0.47 282.1 95.8 0.5 0.6837 0.9996 1972745 ChemDiv1_005094 CCOC(=O)CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H13 compound treatment 281.1 92.4 0.48 279.4 93.1 0.48 0.683 1.0 1924682 ChemDiv1_005095 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H14 compound treatment 284.8 96.1 0.5 284.1 97.8 0.51 0.714 1.0 1972746 ChemDiv1_005096 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc5CCCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H15 compound treatment 281.2 92.5 0.48 282.7 96.4 0.5 0.6955 0.9998 1438246 ChemDiv1_005097 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3ccccc3Cl)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H16 compound treatment 282.1 93.4 0.49 283.0 96.7 0.5 0.7 0.9999 1972747 ChemDiv1_005098 Cc1ccc(cc1)S(=O)(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H17 compound treatment 278.9 90.2 0.47 277.9 91.6 0.48 0.6694 1.0 1972748 ChemDiv1_005099 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(Cc5ccc(cc5)N6C(=O)C7C8CC(C=C8)C7C6=O)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H18 compound treatment 277.5 88.8 0.46 278.8 92.5 0.48 0.6676 0.9998 1702817 ChemDiv1_005100 COc1ccc(OCC(O)Cn2c(NCc3ccco3)nc4n(C)c(=O)n(C)c(=O)c24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H19 compound treatment 279.0 90.3 0.47 278.3 92.0 0.48 0.6713 1.0 1336807 ChemDiv1_005101 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)c5ccc(cc5)S(=O)(=O)N6CCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H20 compound treatment 282.1 93.4 0.49 281.4 95.1 0.49 0.6941 1.0 1343040 ChemDiv1_005102 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCN(C)CC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H21 compound treatment 277.3 88.6 0.46 278.8 92.5 0.48 0.6668 0.9998 1345782 ChemDiv1_005103 COc1cc(OC)cc(c1)C(=O)Nc2nc3ccccc3c4nc5ccccc5n24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H22 compound treatment 277.4 88.7 0.46 279.0 92.7 0.48 0.6679 0.9998 1184639 ChemDiv1_005104 C(Cn1c2ccccc2c3nc4ccccc4nc13)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H23 mock treatment 278.9 90.2 0.47 279.9 93.6 0.49 0.6768 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 H24 mock treatment 78.6 -110.0 -0.57 81.2 -105.0 -0.55 -0.7924 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I01 compound treatment 280.4 91.7 0.48 283.9 97.6 0.51 0.697 0.9996 1972749 ChemDiv1_005105 COC(=O)c1ccc(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I02 compound treatment 280.7 92.0 0.48 282.3 96.0 0.5 0.6922 0.9998 1407374 ChemDiv1_005106 COc1ccc(cc1OC)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I03 compound treatment 282.1 93.4 0.49 285.9 99.6 0.52 0.7106 0.9995 1473917 ChemDiv1_005107 Cn1c(=O)n(C)c2nc(N3CCCCCC3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I04 compound treatment 283.4 94.7 0.49 285.6 99.3 0.52 0.7143 0.9998 1734725 ChemDiv1_005108 CC1=C(C(c2ccc(Cl)cc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I05 compound treatment 286.6 97.9 0.51 283.9 97.6 0.51 0.7199 1.0 1972750 ChemDiv1_005109 Cc1ccc(cc1)C2=NN(C(Cc3cc4cccc(C)c4[nH]c3=O)C2)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I06 compound treatment 284.5 95.8 0.5 282.5 96.2 0.5 0.707 1.0 1620598 ChemDiv1_005110 CC1=C(C(c2ccc(Br)cc2)n3nnnc3N1)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I07 compound treatment 283.5 94.8 0.49 284.0 97.7 0.51 0.7088 0.9999 1972751 ChemDiv1_005111 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4cccs4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I08 compound treatment 283.6 94.9 0.5 288.0 102.0 0.53 0.7239 0.9995 1594581 ChemDiv1_005112 Cc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I09 compound treatment 284.5 95.8 0.5 283.6 97.3 0.51 0.711 1.0 1582217 ChemDiv1_005113 COc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccc(C)cc4)c5ccccc5)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I10 compound treatment 280.9 92.2 0.48 281.6 95.3 0.5 0.6904 0.9999 1481630 ChemDiv1_005114 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I11 compound treatment 276.3 87.6 0.46 283.8 97.5 0.51 0.6815 0.9987 1251440 ChemDiv1_005115 O=C(Nc1nc2CCCCc2s1)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I12 compound treatment 278.5 89.8 0.47 281.6 95.3 0.5 0.6815 0.9996 1972752 ChemDiv1_005116 COc1ccccc1C2CC(=NN2C(=O)CN3CCCC3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I13 compound treatment 285.5 96.8 0.51 289.5 103.0 0.54 0.7364 0.9996 1283308 ChemDiv1_005117 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I14 compound treatment 282.3 93.6 0.49 283.8 97.5 0.51 0.7036 0.9998 1657584 ChemDiv1_005118 CC(=O)Nc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I15 compound treatment 284.0 95.3 0.5 281.4 95.1 0.49 0.7011 1.0 1484528 ChemDiv1_005119 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I16 compound treatment 283.0 94.3 0.49 282.6 96.3 0.5 0.7018 1.0 1972753 ChemDiv1_005120 Cc1ccc(o1)c2csc(NC(=O)c3cc(nc4ccccc34)c5cccs5)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I17 compound treatment 283.2 94.5 0.49 281.9 95.6 0.5 0.7 1.0 1621567 ChemDiv1_005121 CC1=C(C(c2ccccc2Cl)n3ncnc3N1)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I18 compound treatment 283.6 94.9 0.5 279.0 92.7 0.48 0.6908 0.9999 1605536 ChemDiv1_005122 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I19 compound treatment 284.4 95.7 0.5 275.4 89.1 0.46 0.6805 0.9993 1874354 ChemDiv1_005123 COC(=O)C1=C(C)Nc2nnnn2C1c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I20 compound treatment 278.5 89.8 0.47 277.7 91.4 0.47 0.6672 1.0 1972754 ChemDiv1_005124 CC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I21 compound treatment 276.7 88.0 0.46 280.4 94.1 0.49 0.6705 0.9995 1736427 ChemDiv1_005125 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(cc3)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I22 compound treatment 279.3 90.6 0.47 275.4 89.1 0.46 0.6617 0.9999 1199312 ChemDiv1_005126 COc1cc(ccc1OC(=O)c2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I23 mock treatment 282.6 93.9 0.49 280.9 94.6 0.49 0.6941 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 I24 mock treatment 88.1 -101.0 -0.52 85.6 -101.0 -0.52 -0.7412 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J01 compound treatment 286.0 97.3 0.51 282.3 96.0 0.5 0.7118 1.0 1603355 ChemDiv1_005127 CCOc1cc(ccc1OC(=O)c2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J02 compound treatment 284.9 96.2 0.5 282.3 96.0 0.5 0.7077 1.0 1373732 ChemDiv1_005128 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccc(C)cc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J03 compound treatment 285.6 96.9 0.51 285.0 98.7 0.51 0.7202 1.0 1972755 ChemDiv1_005129 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4cc(Br)ccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J04 compound treatment 282.3 93.6 0.49 281.4 95.1 0.49 0.6948 1.0 1361775 ChemDiv1_005130 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc(c3)c4nc5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J05 compound treatment 281.8 93.1 0.49 282.7 96.4 0.5 0.6978 0.9999 1598839 ChemDiv1_005131 Cc1ccccc1n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J06 compound treatment 279.1 90.4 0.47 283.1 96.8 0.5 0.6893 0.9995 1972756 ChemDiv1_005132 COc1cccc(OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J07 compound treatment 283.5 94.8 0.49 281.7 95.4 0.5 0.7003 1.0 1163398 ChemDiv1_005133 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J08 compound treatment 282.1 93.4 0.49 280.6 94.3 0.49 0.6911 1.0 1972757 ChemDiv1_005134 OC(COCC1COc2ccccc2O1)CN3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J09 compound treatment 280.1 91.4 0.48 282.6 96.3 0.5 0.6911 0.9997 1342219 ChemDiv1_005135 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4nc(SC)sc4c3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J10 compound treatment 283.3 94.6 0.49 282.7 96.4 0.5 0.7033 1.0 1972758 ChemDiv1_005136 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC5)S(=O)(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J11 compound treatment 280.9 92.2 0.48 272.3 86.0 0.45 0.6562 0.9993 1173897 ChemDiv1_005137 CCOC(=O)C1=C(N)Oc2cc(C)oc(=O)c2C1c3cccc(Br)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J12 compound treatment 279.7 91.0 0.47 275.5 89.2 0.46 0.6635 0.9999 1972759 ChemDiv1_005138 O=C(CSc1nnc(CCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6cccnc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J13 compound treatment 283.1 94.4 0.49 281.7 95.4 0.5 0.6989 1.0 1924582 ChemDiv1_005139 O=C1N(CC2CCN(CC2)S(=O)(=O)c3cccc4cccnc34)C(=O)c5cccc6cccc1c56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J14 compound treatment 280.3 91.6 0.48 277.7 91.4 0.47 0.6738 1.0 1972760 ChemDiv1_005140 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc5CCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J15 compound treatment 278.1 89.4 0.47 279.9 93.6 0.49 0.6738 0.9998 1388128 ChemDiv1_005141 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OCc3ccccc3F)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J16 compound treatment 278.8 90.1 0.47 277.4 91.1 0.47 0.6672 1.0 1972761 ChemDiv1_005142 O=C(CCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J17 compound treatment 282.8 94.1 0.49 280.5 94.2 0.49 0.6934 1.0 1972762 ChemDiv1_005143 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(cc4)S(=O)(=O)c5ccc(cc5)N6C(=O)C7C8CC(C=C8)C7C6=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J18 compound treatment 278.7 90.0 0.47 281.1 94.8 0.49 0.6804 0.9997 1972763 ChemDiv1_005144 CN(C)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J19 compound treatment 282.2 93.5 0.49 278.6 92.3 0.48 0.6842 1.0 1532629 ChemDiv1_005145 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J20 compound treatment 282.7 94.0 0.49 279.0 92.7 0.48 0.6875 1.0 1498601 ChemDiv1_005146 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCOCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J21 compound treatment 284.7 96.0 0.5 280.9 94.6 0.49 0.7018 1.0 1468534 ChemDiv1_005147 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)c4ccc(cc4)S(=O)(=O)N5CCCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J22 compound treatment 277.7 89.0 0.46 279.2 92.9 0.48 0.6698 0.9998 1244709 ChemDiv1_005148 Clc1ccccc1Cn2c3ccccc3c4nc5ccccc5nc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J23 mock treatment 277.1 88.4 0.46 277.2 90.9 0.47 0.6602 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 J24 mock treatment 77.8 -111.0 -0.58 75.5 -111.0 -0.58 -0.8163 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K01 compound treatment 283.8 95.1 0.5 284.5 98.2 0.51 0.7117 0.9999 1705922 ChemDiv1_005149 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OC(C)(C)C)c3ccc(Cl)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K02 compound treatment 284.3 95.6 0.5 285.3 99.0 0.51 0.7165 0.9999 1118186 ChemDiv1_005150 COc1ccc(OC)c(c1)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K03 compound treatment 282.3 93.6 0.49 282.6 96.3 0.5 0.6992 0.9999 1484767 ChemDiv1_005151 CC(=O)N1N=C(CC1Cc2cc3cccc(C)c3nc2Cl)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K04 compound treatment 281.0 92.3 0.48 281.9 95.6 0.5 0.6919 0.9999 1632319 ChemDiv1_005152 CC1=C(C(c2ccc(Br)cc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K05 compound treatment 286.8 98.1 0.51 286.5 100.0 0.52 0.7302 1.0 1972764 ChemDiv1_005153 Cc1cccc2cc(CC3CC(=NN3C(=O)CCC(=O)O)c4ccc(Br)cc4)c(=O)[nH]c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K06 compound treatment 285.2 96.5 0.5 283.8 97.5 0.51 0.7143 1.0 1222959 ChemDiv1_005154 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K07 compound treatment 286.8 98.1 0.51 288.1 102.0 0.53 0.736 0.9999 1972765 ChemDiv1_005155 Fc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K08 compound treatment 284.3 95.6 0.5 279.9 93.6 0.49 0.6967 0.9999 1972766 ChemDiv1_005156 [O-][N+](=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K09 compound treatment 280.3 91.6 0.48 282.3 96.0 0.5 0.6907 0.9998 1372596 ChemDiv1_005157 Cc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K10 compound treatment 284.3 95.6 0.5 281.4 95.1 0.49 0.7022 1.0 1280204 ChemDiv1_005158 Clc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K11 compound treatment 283.1 94.4 0.49 280.2 93.9 0.49 0.6934 1.0 1972767 ChemDiv1_005159 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc6C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K12 compound treatment 281.3 92.6 0.48 277.5 91.2 0.47 0.6768 1.0 1972768 ChemDiv1_005160 Cc1ccc(Sc2c(nc3ccccn23)c4ccc(Br)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K13 compound treatment 277.5 88.8 0.46 280.2 93.9 0.49 0.6727 0.9997 1241843 ChemDiv1_005161 CC1=C(C(c2ccccc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K14 compound treatment 285.4 96.7 0.5 284.4 98.1 0.51 0.7173 1.0 1972769 ChemDiv1_005162 O=C(Nc1nc(cs1)c2cc3ccccc3oc2=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K15 compound treatment 280.7 92.0 0.48 277.1 90.8 0.47 0.6731 1.0 1874367 ChemDiv1_005163 CC1=C(C(c2cccc(c2)[N+](=O)[O-])n3ncnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K16 compound treatment 277.7 89.0 0.46 278.9 92.6 0.48 0.6687 0.9998 1150618 ChemDiv1_005164 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3c(ccc4ccccc34)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K17 compound treatment 281.7 93.0 0.49 279.3 93.0 0.48 0.6849 1.0 1154289 ChemDiv1_005165 COc1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K18 compound treatment 277.8 89.1 0.46 275.2 88.9 0.46 0.6554 1.0 1342192 ChemDiv1_005166 OC(=O)CCC(=O)N1N=C(CC1c2cccs2)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K19 compound treatment 279.1 90.4 0.47 296.2 110.0 0.57 0.7374 0.9955 1717539 ChemDiv1_005167 COC(=O)C1=C(C)Nc2nnnn2C1c3ccc(cc3)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K20 compound treatment 281.9 93.2 0.49 277.1 90.8 0.47 0.6775 0.9999 1408791 ChemDiv1_005168 COC(=O)C1=C(C)Nc2ncnn2C1c3ccc4ncccc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K21 compound treatment 276.8 88.1 0.46 276.0 89.7 0.47 0.6547 1.0 1641304 ChemDiv1_005169 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cc(OC)ccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K22 compound treatment 277.5 88.8 0.46 282.3 96.0 0.5 0.6804 0.9993 1212451 ChemDiv1_005170 CCOc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K23 mock treatment 278.8 90.1 0.47 274.3 88.0 0.46 0.6558 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 K24 mock treatment 78.6 -110.0 -0.57 79.1 -107.0 -0.56 -0.8001 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L01 compound treatment 281.8 93.1 0.49 283.8 97.5 0.51 0.7018 0.9998 1363123 ChemDiv1_005171 CC1=C(C(c2ccc3OCOc3c2)n4ncnc4N1)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L02 compound treatment 285.1 96.4 0.5 286.5 100.0 0.52 0.7239 0.9999 1251416 ChemDiv1_005172 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(NC(=O)C)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L03 compound treatment 284.6 95.9 0.5 277.1 90.8 0.47 0.6875 0.9996 1972770 ChemDiv1_005173 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L04 compound treatment 281.8 93.1 0.49 280.9 94.6 0.49 0.6911 1.0 1574019 ChemDiv1_005174 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L05 compound treatment 282.0 93.3 0.49 280.8 94.5 0.49 0.6915 1.0 1330420 ChemDiv1_005175 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L06 compound treatment 284.9 96.2 0.5 286.3 100.0 0.52 0.7224 0.9999 1972771 ChemDiv1_005176 COc1cccc(OCC(O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L07 compound treatment 284.0 95.3 0.5 282.8 96.5 0.5 0.7062 1.0 1972772 ChemDiv1_005177 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L08 compound treatment 281.7 93.0 0.49 280.6 94.3 0.49 0.6897 1.0 1972773 ChemDiv1_005178 OC(COc1ccc(F)cc1)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L09 compound treatment 278.9 90.2 0.47 283.1 96.8 0.5 0.6885 0.9994 1416651 ChemDiv1_005179 CSc1nc2ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5)sc3c2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L10 compound treatment 278.0 89.3 0.47 278.2 91.9 0.48 0.6672 0.9999 1972774 ChemDiv1_005180 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L11 compound treatment 277.7 89.0 0.46 281.2 94.9 0.49 0.6771 0.9996 1925016 ChemDiv1_005181 COc1ccc(cc1)S(=O)(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L12 compound treatment 280.0 91.3 0.48 276.8 90.5 0.47 0.6694 1.0 1972775 ChemDiv1_005182 O=C(CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCN6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L13 compound treatment 282.1 93.4 0.49 282.9 96.6 0.5 0.6996 0.9999 1972776 ChemDiv1_005183 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCCCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L14 compound treatment 279.7 91.0 0.47 277.2 90.9 0.47 0.6698 1.0 1972777 ChemDiv1_005184 O=C(CSc1nnc2sc3ccccc3n12)NC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L15 compound treatment 279.3 90.6 0.47 277.3 91.0 0.47 0.6687 1.0 1301772 ChemDiv1_005185 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3cccc(Cl)c3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L16 compound treatment 281.9 93.2 0.49 281.2 94.9 0.49 0.6926 1.0 1205223 ChemDiv1_005186 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCOCC4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L17 compound treatment 275.9 87.2 0.46 281.4 95.1 0.49 0.6712 0.9992 1972778 ChemDiv1_005187 OC(=O)C(Cc1c[nH]c2ccccc12)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L18 compound treatment 280.9 92.2 0.48 281.4 95.1 0.49 0.6897 0.9999 1972779 ChemDiv1_005188 CCN(CC)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L19 compound treatment 280.8 92.1 0.48 290.5 104.0 0.54 0.7227 0.9982 1347464 ChemDiv1_005189 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccccc3c4nc5ccccc5n24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L20 compound treatment 280.6 91.9 0.48 281.2 94.9 0.49 0.6878 0.9999 1633496 ChemDiv1_005190 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCCCCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L21 compound treatment 279.8 91.1 0.48 276.6 90.3 0.47 0.668 1.0 1518368 ChemDiv1_005191 CCOC(=O)Cc1csc(NC(=S)NC(=O)c2sc3ccccc3c2Cl)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L22 compound treatment 278.7 90.0 0.47 277.3 91.0 0.47 0.6665 1.0 1518130 ChemDiv1_005192 Cn1c(SCC(=O)NCc2ccccn2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L23 mock treatment 279.6 90.9 0.47 278.5 92.2 0.48 0.6742 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 L24 mock treatment 81.7 -107.0 -0.56 83.0 -103.0 -0.54 -0.7744 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M01 compound treatment 289.1 100.0 0.52 283.9 97.6 0.51 0.7291 0.9999 1156178 ChemDiv1_005193 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2CC(O)COc4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M02 compound treatment 286.2 97.5 0.51 285.6 99.3 0.52 0.7246 1.0 1586133 ChemDiv1_005194 CC1=C(C(c2ccc(Br)cc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M03 compound treatment 282.6 93.9 0.49 281.3 95.0 0.49 0.6956 1.0 1708821 ChemDiv1_005195 Cc1cccc2cc(CC3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(Cl)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M04 compound treatment 282.9 94.2 0.49 282.3 96.0 0.5 0.7003 1.0 1228364 ChemDiv1_005196 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M05 compound treatment 290.3 102.0 0.53 290.4 104.0 0.54 0.7574 0.9999 1730659 ChemDiv1_005197 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M06 compound treatment 283.5 94.8 0.49 278.2 91.9 0.48 0.6875 0.9998 1276304 ChemDiv1_005198 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M07 compound treatment 279.8 91.1 0.48 281.2 94.9 0.49 0.6849 0.9998 1244056 ChemDiv1_005199 Cc1cccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c(Cl)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M08 compound treatment 287.1 98.4 0.51 279.3 93.0 0.48 0.7048 0.9995 1219328 ChemDiv1_005200 CC1CCc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M09 compound treatment 281.0 92.3 0.48 280.7 94.4 0.49 0.6875 1.0 1135249 ChemDiv1_005201 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCC(=O)O)c4ccc(Br)cc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M10 compound treatment 292.4 104.0 0.54 295.6 109.0 0.57 0.7843 0.9997 1972780 ChemDiv1_005202 Brc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M11 compound treatment 285.1 96.4 0.5 284.7 98.4 0.51 0.7173 1.0 1972781 ChemDiv1_005203 COC(=O)c1ccc(cc1)C(=O)Nc2nc(c3cccs3)c(s2)C(=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M12 compound treatment 284.4 95.7 0.5 281.9 95.6 0.5 0.7044 1.0 1639426 ChemDiv1_005204 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc6C5)sc32)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M13 compound treatment 280.7 92.0 0.48 283.9 97.6 0.51 0.6981 0.9996 1874360 ChemDiv1_005205 CC1=C(C(c2ccc(cc2)[N+](=O)[O-])n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M14 compound treatment 283.5 94.8 0.49 280.9 94.6 0.49 0.6974 1.0 1972782 ChemDiv1_005206 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M15 compound treatment 280.7 92.0 0.48 279.5 93.2 0.48 0.6819 1.0 1686726 ChemDiv1_005207 CC1=C(C(c2ccccc2Cl)n3ncnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M16 compound treatment 284.2 95.5 0.5 281.6 95.3 0.5 0.7026 1.0 1194673 ChemDiv1_005208 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3CCCc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M17 compound treatment 280.4 91.7 0.48 279.2 92.9 0.48 0.6797 1.0 1485835 ChemDiv1_005209 COc1ccc(cc1OC)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M18 compound treatment 279.8 91.1 0.48 277.2 90.9 0.47 0.6702 1.0 1531488 ChemDiv1_005210 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M19 compound treatment 280.0 91.3 0.48 279.3 93.0 0.48 0.6786 1.0 1313723 ChemDiv1_005211 COC(=O)C1=C(C)Nc2nnnn2C1c3cc(OC)ccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M20 compound treatment 282.8 94.1 0.49 279.5 93.2 0.48 0.6897 1.0 1455629 ChemDiv1_005212 COC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M21 compound treatment 279.7 91.0 0.47 274.6 88.3 0.46 0.6602 0.9999 1727572 ChemDiv1_005213 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M22 compound treatment 277.0 88.3 0.46 275.6 89.3 0.46 0.654 1.0 1686374 ChemDiv1_005214 CCOc1cc(ccc1OC(=O)c2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M23 mock treatment 279.6 90.9 0.47 280.5 94.2 0.49 0.6816 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 M24 mock treatment 192.1 3.43 0.02 184.6 -1.73 -0.01 0.0063 0.3148 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N01 compound treatment 285.8 97.1 0.51 284.2 97.9 0.51 0.718 1.0 1407895 ChemDiv1_005215 CC1=C(C(c2ccccn2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N02 compound treatment 284.8 96.1 0.5 281.2 94.9 0.49 0.7033 1.0 1259554 ChemDiv1_005216 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(C)cc(C)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N03 compound treatment 285.7 97.0 0.51 280.6 94.3 0.49 0.7044 0.9999 1972783 ChemDiv1_005217 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N04 compound treatment 280.1 91.4 0.48 283.4 97.1 0.5 0.6941 0.9996 1448129 ChemDiv1_005218 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc(c3)c4nc5ccccc5[nH]4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N05 compound treatment 284.1 95.4 0.5 277.7 91.4 0.47 0.6879 0.9997 1972784 ChemDiv1_005219 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N06 compound treatment 280.0 91.3 0.48 278.9 92.6 0.48 0.6771 1.0 1972785 ChemDiv1_005220 Cc1ccc(OCC(O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N07 compound treatment 280.7 92.0 0.48 280.0 93.7 0.49 0.6838 1.0 1162532 ChemDiv1_005221 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N08 compound treatment 279.8 91.1 0.48 283.7 97.4 0.51 0.6941 0.9995 1972786 ChemDiv1_005222 OC(COc1ccccc1CC=C)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N09 compound treatment 276.5 87.8 0.46 280.5 94.2 0.49 0.6701 0.9995 1635437 ChemDiv1_005223 CSc1nc2ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5)sc3c2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N10 compound treatment 280.1 91.4 0.48 283.0 96.7 0.5 0.6926 0.9997 1547630 ChemDiv1_005224 COc1ccc(cc1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N11 compound treatment 280.3 91.6 0.48 277.7 91.4 0.47 0.6738 1.0 1925128 ChemDiv1_005225 O=C1N(CC2CCN(CC2)S(=O)(=O)c3cccs3)C(=O)c4cccc5cccc1c45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N12 compound treatment 281.2 92.5 0.48 280.9 94.6 0.49 0.6889 1.0 1972787 ChemDiv1_005226 COC(=O)c1ccc(CN2CCN(CCN3C(=O)C4C5CC(C=C5)C4C3=O)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N13 compound treatment 278.8 90.1 0.47 277.1 90.8 0.47 0.6661 1.0 1925203 ChemDiv1_005227 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)c4ccc(NS(=O)(=O)c5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N14 compound treatment 279.6 90.9 0.47 282.4 96.1 0.5 0.6885 0.9997 1972788 ChemDiv1_005228 Cc1cc(NC(=O)c2ccc3OCCOc3c2)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N15 compound treatment 278.5 89.8 0.47 279.7 93.4 0.49 0.6746 0.9998 1972789 ChemDiv1_005229 CCOC(=O)c1c(oc2cc(Br)c(OCc3ccc(cc3)[N+](=O)[O-])cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N16 compound treatment 278.1 89.4 0.47 281.9 95.6 0.5 0.6812 0.9995 1972790 ChemDiv1_005230 CN(C)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N17 compound treatment 278.2 89.5 0.47 280.9 94.6 0.49 0.6779 0.9997 1265983 ChemDiv1_005231 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(cc4)S(=O)(=O)Nc5nccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N18 compound treatment 280.6 91.9 0.48 276.7 90.4 0.47 0.6713 0.9999 1568399 ChemDiv1_005232 Cn1c(=O)n(C)c2nc(S)n(Cc3ccc(F)cc3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N19 compound treatment 283.7 95.0 0.5 277.6 91.3 0.47 0.686 0.9998 1594393 ChemDiv1_005233 CC1(CC2CC(C)(C)C1)CN2S(=O)(=O)c3ccc(cc3)C(=O)Nc4cccc(c4)c5nc6ccccc6[nH]5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N20 compound treatment 278.5 89.8 0.47 276.9 90.6 0.47 0.6643 1.0 1972791 ChemDiv1_005234 Cc1ccccc1OCC(O)Cn2c(NCCCn3ccnc3)nc4n(C)c(=O)n(C)c(=O)c24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N21 compound treatment 275.8 87.1 0.45 273.3 87.0 0.45 0.6411 1.0 1448163 ChemDiv1_005235 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(OC)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N22 compound treatment 281.7 93.0 0.49 279.0 92.7 0.48 0.6838 1.0 1512613 ChemDiv1_005236 Cn1c(SCc2ccc(cc2)C(=O)NCCO)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N23 mock treatment 280.5 91.8 0.48 274.7 88.4 0.46 0.6636 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 N24 mock treatment 198.8 10.1 0.05 182.1 -4.23 -0.02 0.0218 0.3814 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O01 compound treatment 281.7 93.0 0.49 288.3 102.0 0.53 0.718 0.999 1426253 ChemDiv1_005237 Cc1ccccc1OCC(O)Cn2c(NCc3ccccc3)nc4n(C)c(=O)n(C)c(=O)c24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O02 compound treatment 281.1 92.4 0.48 282.3 96.0 0.5 0.6937 0.9999 1628501 ChemDiv1_005238 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O03 compound treatment 285.0 96.3 0.5 282.3 96.0 0.5 0.7081 1.0 1351269 ChemDiv1_005239 CC(=O)N1N=C(CC1Cc2cc3cccc(C)c3[nH]c2=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O04 compound treatment 286.0 97.3 0.51 286.6 100.0 0.52 0.7276 0.9999 1263263 ChemDiv1_005240 CC1=C(C(c2ccc(OCc3ccccc3)cc2)n4nnnc4N1)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O05 compound treatment 284.8 96.1 0.5 282.8 96.5 0.5 0.7092 1.0 1972792 ChemDiv1_005241 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O06 compound treatment 278.2 89.5 0.47 280.3 94.0 0.49 0.6757 0.9997 1537433 ChemDiv1_005242 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O07 compound treatment 280.4 91.7 0.48 281.8 95.5 0.5 0.6893 0.9998 1432170 ChemDiv1_005243 Cc1ccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c(Cl)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O08 compound treatment 285.0 96.3 0.5 283.7 97.4 0.51 0.7132 1.0 1313363 ChemDiv1_005244 Cc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O09 compound treatment 286.9 98.2 0.51 283.4 97.1 0.5 0.7191 1.0 1972793 ChemDiv1_005245 Brc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O10 compound treatment 290.7 102.0 0.53 289.0 103.0 0.53 0.7537 1.0 1675957 ChemDiv1_005246 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O11 compound treatment 276.4 87.7 0.46 279.1 92.8 0.48 0.6646 0.9997 1972794 ChemDiv1_005247 Nc1ncnc(Sc2nc3ccccc3o2)c1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O12 compound treatment 281.8 93.1 0.49 274.3 88.0 0.46 0.6669 0.9995 1553500 ChemDiv1_005248 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56)sc32)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O13 compound treatment 279.8 91.1 0.48 275.5 89.2 0.46 0.6639 0.9999 1200470 ChemDiv1_005249 CC1=C(C(c2ccc(Cl)cc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O14 compound treatment 282.0 93.3 0.49 275.7 89.4 0.46 0.6728 0.9997 1666456 ChemDiv1_005250 O=C(Nc1ccccc1c2nc3ccccc3[nH]2)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O15 compound treatment 278.5 89.8 0.47 279.5 93.2 0.48 0.6738 0.9999 1159530 ChemDiv1_005251 CN(C)c1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O16 compound treatment 278.6 89.9 0.47 281.8 95.5 0.5 0.6826 0.9996 1972795 ChemDiv1_005252 [O-][N+](=O)c1cccc(c1)C2CC(=NN2C(=O)c3cccs3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O17 compound treatment 282.1 93.4 0.49 282.4 96.1 0.5 0.6978 0.9999 1198680 ChemDiv1_005253 CN(C)c1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O18 compound treatment 281.0 92.3 0.48 282.7 96.4 0.5 0.6948 0.9998 1524008 ChemDiv1_005254 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O19 compound treatment 276.1 87.4 0.46 275.7 89.4 0.46 0.651 1.0 1673712 ChemDiv1_005255 COC(=O)C1=C(C)Nc2nnnn2C1c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O20 compound treatment 278.3 89.6 0.47 273.9 87.6 0.46 0.6525 0.9999 1216323 ChemDiv1_005256 CCOC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O21 compound treatment 279.6 90.9 0.47 279.1 92.8 0.48 0.6764 1.0 1226642 ChemDiv1_005257 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OCc4ccccc4)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O22 compound treatment 280.8 92.1 0.48 279.6 93.3 0.48 0.6827 1.0 1340233 ChemDiv1_005258 CC1=C(C(c2ccc3OCOc3c2)n4nnnc4N1)C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O23 mock treatment 277.7 89.0 0.46 277.6 91.3 0.47 0.6639 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 O24 mock treatment 96.7 -92.0 -0.48 89.7 -96.6 -0.5 -0.6944 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P01 compound treatment 286.2 97.5 0.51 288.7 102.0 0.53 0.736 0.9997 1224440 ChemDiv1_005259 CC1=C(C(c2ccc(O)cc2)n3ncnc3N1)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P02 compound treatment 281.7 93.0 0.49 282.1 95.8 0.5 0.6952 0.9999 1519181 ChemDiv1_005260 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc4sc(C)nc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P03 compound treatment 282.2 93.5 0.49 285.2 98.9 0.51 0.7084 0.9997 1972796 ChemDiv1_005261 Cc1onc(c1C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-])c5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P04 compound treatment 285.3 96.6 0.5 284.3 98.0 0.51 0.7165 1.0 1238521 ChemDiv1_005262 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5nc(SC)sc5c4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P05 compound treatment 280.5 91.8 0.48 284.7 98.4 0.51 0.7003 0.9995 1409682 ChemDiv1_005263 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P06 compound treatment 281.6 92.9 0.48 279.5 93.2 0.48 0.6853 1.0 1972797 ChemDiv1_005264 OC(COCc1ccc(Cl)cc1)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P07 compound treatment 282.4 93.7 0.49 279.1 92.8 0.48 0.6867 1.0 1179247 ChemDiv1_005265 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4cc(C)cc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P08 compound treatment 281.2 92.5 0.48 282.8 96.5 0.5 0.6959 0.9998 1972798 ChemDiv1_005266 COc1ccc(OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P09 compound treatment 279.6 90.9 0.47 282.9 96.6 0.5 0.6904 0.9996 1166468 ChemDiv1_005267 CSc1nc2ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CC(C)OC(C)C5)sc3c2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P10 compound treatment 280.5 91.8 0.48 280.0 93.7 0.49 0.683 1.0 1972799 ChemDiv1_005268 Clc1ccc(OCC(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P11 compound treatment 277.8 89.1 0.46 289.0 103.0 0.53 0.7062 0.9976 1924720 ChemDiv1_005269 Fc1ccc(cc1)S(=O)(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P12 compound treatment 279.3 90.6 0.47 283.8 97.5 0.51 0.6926 0.9994 1736814 ChemDiv1_005270 COC(=O)c1ccc(CSc2nc3sc4CCCc4c3c(=O)n2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P13 compound treatment 276.3 87.6 0.46 280.2 93.9 0.49 0.6683 0.9995 1925272 ChemDiv1_005271 CCOC(=O)c1c(oc2cc(Br)c(OS(=O)(=O)C)cc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P14 compound treatment 279.5 90.8 0.47 281.4 95.1 0.49 0.6845 0.9998 1972800 ChemDiv1_005272 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC6CC7CC(C6)C5)C7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P15 compound treatment 280.7 92.0 0.48 280.9 94.6 0.49 0.6871 0.9999 1925045 ChemDiv1_005273 CCOC(=O)c1c(oc2cc(Br)c(OCC(=O)C(C)(C)C)cc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P16 compound treatment 277.8 89.1 0.46 282.3 96.0 0.5 0.6815 0.9994 1972801 ChemDiv1_005274 CCN(CC)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P17 compound treatment 272.3 83.6 0.44 281.2 94.9 0.49 0.6572 0.9981 1972802 ChemDiv1_005275 C=CCn1c(CCCN2C(=O)c3cccc4cccc(C2=O)c34)nnc1SCC(=O)NCc5cccnc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P18 compound treatment 283.2 94.5 0.49 279.5 93.2 0.48 0.6912 1.0 1431996 ChemDiv1_005276 COc1ccc(OCC(O)Cn2c(NCCN(C)C)nc3n(C)c(=O)n(C)c(=O)c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P19 compound treatment 279.5 90.8 0.47 280.6 94.3 0.49 0.6816 0.9999 1231993 ChemDiv1_005277 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P20 compound treatment 278.1 89.4 0.47 278.9 92.6 0.48 0.6701 0.9999 1972803 ChemDiv1_005278 COc1ccc(OCC(O)Cn2c(NCCCn3ccnc3)nc4n(C)c(=O)n(C)c(=O)c24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P21 compound treatment 276.0 87.3 0.46 281.6 95.3 0.5 0.6723 0.9991 1464765 ChemDiv1_005279 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(OCC)cc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P22 compound treatment 278.7 90.0 0.47 277.5 91.2 0.47 0.6672 1.0 1972804 ChemDiv1_005280 CCCCOC(=O)C1Cc2c([nH]c3ccccc23)C(C)N1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P23 mock treatment 278.7 90.0 0.47 283.2 96.9 0.5 0.6882 0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.601 P24 mock treatment 101.8 -86.9 -0.45 92.2 -94.1 -0.49 -0.6664 -0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A01 compound treatment 288.2 100.0 0.52 285.1 98.9 0.51 0.7332 1.0 1972805 ChemDiv1_005281 [O-][N+](=O)c1ccc2[nH]c(SCc3nc4ncccn4c3Br)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A02 compound treatment 286.5 98.5 0.51 288.9 103.0 0.53 0.7409 0.9998 1293321 ChemDiv1_005282 Brc1ccc(cc1)c2cc(C(=O)Nc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A03 compound treatment 284.8 96.8 0.5 283.1 96.9 0.5 0.7133 1.0 1972806 ChemDiv1_005283 [O-][N+](=O)c1ccc2oc(SCc3nc4ccccn4c3Br)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A04 compound treatment 279.2 91.2 0.48 277.9 91.7 0.48 0.6735 1.0 1320843 ChemDiv1_005284 CCN(CC)C(=O)c1sc(NC(=O)C(Sc2ccccc2)c3ccccc3)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A05 compound treatment 276.8 88.8 0.46 282.5 96.3 0.5 0.6816 0.9992 1782529 ChemDiv1_005285 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4cccc(c4)[N+](=O)[O-])cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A06 compound treatment 278.0 90.0 0.47 286.0 99.8 0.52 0.6989 0.9987 1949890 ChemDiv1_005286 COc1ccc(cc1OC)c2cc(C(=O)Nc3cccc(c3)C(=O)C)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A07 compound treatment 279.7 91.7 0.48 283.1 96.9 0.5 0.6945 0.9997 1972807 ChemDiv1_005287 [O-][N+](=O)c1cccc(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A08 compound treatment 278.7 90.7 0.47 279.5 93.3 0.49 0.6776 0.9999 1382679 ChemDiv1_005288 Cc1nc2sc3CCCc3c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A09 compound treatment 282.4 94.4 0.49 282.9 96.7 0.5 0.7037 0.9999 1972808 ChemDiv1_005289 Clc1ccc(Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A10 compound treatment 281.4 93.4 0.49 286.7 101.0 0.52 0.714 0.9994 1972809 ChemDiv1_005290 Brc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A11 compound treatment 281.7 93.7 0.49 277.5 91.3 0.47 0.6813 0.9999 1242730 ChemDiv1_005291 CCOc1cccc(c1)c2cc(C(=O)Nc3ccc4OCOc4c3)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A12 compound treatment 275.4 87.4 0.46 280.6 94.4 0.49 0.6694 0.9993 1477240 ChemDiv1_005292 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A13 compound treatment 279.1 91.1 0.48 281.7 95.5 0.5 0.6871 0.9998 1972810 ChemDiv1_005293 Cc1onc(c1C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23)c5c(Cl)cccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A14 compound treatment 275.9 87.9 0.46 278.6 92.4 0.48 0.6639 0.9997 1391846 ChemDiv1_005294 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A15 compound treatment 276.2 88.2 0.46 278.2 92.0 0.48 0.6636 0.9998 1473341 ChemDiv1_005295 COc1ccc(c(OC)c1)c2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A16 compound treatment 279.3 91.3 0.48 279.0 92.8 0.48 0.6779 1.0 1371826 ChemDiv1_005296 CCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A17 compound treatment 274.6 86.6 0.45 276.2 90.0 0.47 0.6503 0.9998 1607802 ChemDiv1_005297 Cc1ccc(cc1C)c2cc(C(=O)Nc3ccccc3C(=O)N)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A18 compound treatment 277.6 89.6 0.47 277.6 91.4 0.48 0.6665 1.0 1670585 ChemDiv1_005298 CN(C)c1nc(nc(n1)N(CCOc2ccccc2)C#N)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A19 compound treatment 275.9 87.9 0.46 279.8 93.6 0.49 0.6683 0.9996 1342940 ChemDiv1_005299 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3sc4CC(CCc4c3C#N)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A20 compound treatment 278.9 90.9 0.47 275.2 89.0 0.46 0.6625 0.9999 1558173 ChemDiv1_005300 Cc1cc(Cl)ccc1OCC(=O)Nc2ncnc3sc4CCCCc4c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A21 compound treatment 284.5 96.5 0.5 282.1 95.9 0.5 0.7085 1.0 1175527 ChemDiv1_005301 COc1ccc(cc1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A22 compound treatment 277.0 89.0 0.46 273.9 87.7 0.46 0.6507 1.0 1140805 ChemDiv1_005302 O=C(Nc1cccc2cccnc12)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A23 mock treatment 280.3 92.3 0.48 277.1 90.9 0.47 0.6746 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 A24 mock treatment 70.7 -117.0 -0.61 76.7 -109.0 -0.57 -0.8351 -0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B01 compound treatment 282.4 94.4 0.49 286.9 101.0 0.52 0.7184 0.9995 1334366 ChemDiv1_005303 NC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B02 compound treatment 282.2 94.2 0.49 281.5 95.3 0.5 0.6978 1.0 1972811 ChemDiv1_005304 CC1CC(N(C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)c4ccccc4N1C(=O)c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B03 compound treatment 283.4 95.4 0.5 287.3 101.0 0.53 0.7236 0.9996 1972812 ChemDiv1_005305 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC(=O)N)n42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B04 compound treatment 279.2 91.2 0.48 282.5 96.3 0.5 0.6904 0.9997 1727616 ChemDiv1_005306 CCOc1ccccc1C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)cc5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B05 compound treatment 281.9 93.9 0.49 280.5 94.3 0.49 0.693 1.0 1684723 ChemDiv1_005307 O=C(N1CCSC1c2ccc3CCc4cccc2c43)c5cc6ccccc6oc5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B06 compound treatment 281.1 93.1 0.49 280.6 94.4 0.49 0.6904 1.0 1972813 ChemDiv1_005308 [O-][N+](=O)c1cccc(c1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B07 compound treatment 275.7 87.7 0.46 279.9 93.7 0.49 0.668 0.9995 1972814 ChemDiv1_005309 Cc1ccc(cc1S(=O)(=O)Nc2ccc(cc2)c3cn4ccccc4n3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B08 compound treatment 279.7 91.7 0.48 277.9 91.7 0.48 0.6754 1.0 1712803 ChemDiv1_005310 COc1ccc(cc1OC)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B09 compound treatment 278.6 90.6 0.47 282.5 96.3 0.5 0.6882 0.9996 1399782 ChemDiv1_005311 O=C(Nc1cccc(c1)c2cn3ccccc3n2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B10 compound treatment 275.5 87.5 0.46 281.9 95.7 0.5 0.6746 0.9991 1972815 ChemDiv1_005312 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc(cc4)C(F)(F)F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B11 compound treatment 281.3 93.3 0.49 277.6 91.4 0.48 0.6802 0.9999 1508646 ChemDiv1_005313 CCOc1ccc2nc(Nc3nc(O)c4ccccc4n3)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B12 compound treatment 277.1 89.1 0.46 272.0 85.8 0.45 0.6441 0.9998 1972816 ChemDiv1_005314 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B13 compound treatment 276.5 88.5 0.46 282.9 96.7 0.5 0.6819 0.9991 1135592 ChemDiv1_005315 CCCC(=O)N1C(C)CC(N(C(=O)c2ccccc2)c3ccc(F)cc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B14 compound treatment 278.0 90.0 0.47 276.0 89.8 0.47 0.6621 1.0 1972817 ChemDiv1_005316 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B15 compound treatment 281.4 93.4 0.49 276.6 90.4 0.47 0.6769 0.9998 1940250 ChemDiv1_005317 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CN4C(=O)C5CCCCC5C4=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B16 compound treatment 278.4 90.4 0.47 286.8 101.0 0.52 0.7033 0.9987 1972818 ChemDiv1_005318 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccc(cc5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B17 compound treatment 276.0 88.0 0.46 276.9 90.7 0.47 0.658 0.9999 1972819 ChemDiv1_005319 CC1(C)N(C(=O)c2sc3ccccc3c2Cl)c4ccccc4-c5c1ssc5=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B18 compound treatment 275.6 87.6 0.46 276.1 89.9 0.47 0.6536 0.9999 1972820 ChemDiv1_005320 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5cccc(OC(=O)N6CCOCC6)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B19 compound treatment 279.6 91.6 0.48 278.3 92.1 0.48 0.6765 1.0 1972821 ChemDiv1_005321 COc1ccc2nc(SCc3ccc(cc3)[N+](=O)[O-])nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B20 compound treatment 277.0 89.0 0.46 279.3 93.1 0.48 0.6705 0.9998 1972822 ChemDiv1_005322 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B21 compound treatment 279.4 91.4 0.48 279.7 93.5 0.49 0.6809 1.0 1171320 ChemDiv1_005323 CC1CC(N(C(=O)c2ccc(F)cc2)c3ccccc3)c4ccccc4N1C(=O)c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B22 compound treatment 277.2 89.2 0.47 274.9 88.7 0.46 0.6551 1.0 1712115 ChemDiv1_005324 Cc1ccc(cc1C)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B23 mock treatment 277.2 89.2 0.47 276.0 89.8 0.47 0.6592 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 B24 mock treatment 91.2 -96.8 -0.51 75.4 -111.0 -0.58 -0.7643 -0.9979 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C01 compound treatment 283.7 95.7 0.5 285.7 99.5 0.52 0.7188 0.9998 1869051 ChemDiv1_005325 Cc1cc(C)n2cc(CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])nc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C02 compound treatment 281.7 93.7 0.49 283.5 97.3 0.51 0.7033 0.9998 1559645 ChemDiv1_005326 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4)c(C(=O)OC(C)C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C03 compound treatment 283.3 95.3 0.5 280.2 94.0 0.49 0.6971 1.0 1185665 ChemDiv1_005327 Cn1c(=O)n(C)c2nc(SCC(=O)c3ccc(F)cc3)[nH]c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C04 compound treatment 284.7 96.7 0.5 283.2 97.0 0.5 0.7133 1.0 1645637 ChemDiv1_005328 Cc1c(NC(=O)c2cc(nc3ccccc23)c4cccc(Br)c4)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C05 compound treatment 304.2 116.0 0.61 311.8 126.0 0.65 0.8903 0.9993 1187056 ChemDiv1_005329 Oc1nc(SCC(=O)c2c[nH]c3ccccc23)nc4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C06 compound treatment 281.3 93.3 0.49 283.6 97.4 0.51 0.7022 0.9998 1494240 ChemDiv1_005330 COc1ccc(cc1)c2cc(C(=O)N(CC=C)CC=C)c3ccccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C07 compound treatment 278.9 90.9 0.47 282.7 96.5 0.5 0.6901 0.9996 1926394 ChemDiv1_005331 OC(=O)CCC(=O)N1N=C(CC1c2cccs2)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C08 compound treatment 280.1 92.1 0.48 286.2 100.0 0.52 0.7073 0.9992 1631757 ChemDiv1_005332 COc1ccc(cc1)N2C(=O)CC(Sc3nc(CC(C)C)ccc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C09 compound treatment 281.5 93.5 0.49 287.0 101.0 0.52 0.7154 0.9993 1678449 ChemDiv1_005333 O=c1c(=Cc2ccccc2OCc3cccc4ccccc34)sc5nc6ccccc6n15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C10 compound treatment 278.6 90.6 0.47 281.4 95.2 0.5 0.6842 0.9997 1499573 ChemDiv1_005334 CC1CCc2nc(SC3CC(=O)N(C3=O)c4ccccc4)c(C#N)cc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C11 compound treatment 282.3 94.3 0.49 283.2 97.0 0.5 0.7044 0.9999 1950008 ChemDiv1_005335 CCCOc1ccc(cc1)c2cc(C(=O)NCCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C12 compound treatment 278.2 90.2 0.47 277.9 91.7 0.48 0.6698 1.0 1117928 ChemDiv1_005336 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C13 compound treatment 275.0 87.0 0.45 281.6 95.4 0.5 0.6716 0.999 1381311 ChemDiv1_005337 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4cccc(OC)c4)c(C(=O)OC(C)C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C14 compound treatment 277.5 89.5 0.47 279.4 93.2 0.48 0.6728 0.9998 1088388 ChemDiv1_005338 OC1(C2CCc3ccccc3C2=O)C(=O)Nc4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C15 compound treatment 275.0 87.0 0.45 282.5 96.3 0.5 0.6749 0.9988 1566643 ChemDiv1_005339 Clc1ccc(cc1Cl)c2cc(C(=O)NC3CC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C16 compound treatment 276.9 88.9 0.46 279.6 93.4 0.49 0.6713 0.9997 1556213 ChemDiv1_005340 CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C17 compound treatment 276.8 88.8 0.46 277.0 90.8 0.47 0.6614 1.0 1677644 ChemDiv1_005341 COc1cccc(c1)c2cc(C(=O)Nc3ccc4OCCOc4c3)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C18 compound treatment 275.7 87.7 0.46 280.4 94.2 0.49 0.6698 0.9994 1972823 ChemDiv1_005342 CSc1nc(nc(n1)N2CC(=O)N(CCNS(=O)(=O)c3ccc(C)cc3)C2=N)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C19 compound treatment 279.4 91.4 0.48 282.4 96.2 0.5 0.6908 0.9997 1163490 ChemDiv1_005343 COC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4cccc(OC)c4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C20 compound treatment 274.6 86.6 0.45 273.8 87.6 0.46 0.6415 1.0 1972824 ChemDiv1_005344 OC(=O)C1CC=C(Cl)CC1C(=O)Nc2nccs2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C21 compound treatment 273.2 85.2 0.44 273.7 87.5 0.46 0.6359 0.9999 1633899 ChemDiv1_005345 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C22 compound treatment 277.7 89.7 0.47 278.2 92.0 0.48 0.6691 0.9999 1785278 ChemDiv1_005346 O=C(Nc1sc2CCCc2c1C#N)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C23 mock treatment 275.7 87.7 0.46 281.4 95.2 0.5 0.6735 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 C24 mock treatment 76.0 -112.0 -0.58 75.7 -110.0 -0.57 -0.8192 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D01 compound treatment 284.0 96.0 0.5 287.4 101.0 0.53 0.7261 0.9997 1972825 ChemDiv1_005347 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC(=O)c5ccccc5)n42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D02 compound treatment 284.3 96.3 0.5 283.7 97.5 0.51 0.7136 1.0 1972826 ChemDiv1_005348 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)c4cc(cc(c4)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D03 compound treatment 284.3 96.3 0.5 287.2 101.0 0.53 0.7265 0.9998 1316362 ChemDiv1_005349 COC(=O)CCSc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D04 compound treatment 282.1 94.1 0.49 287.1 101.0 0.52 0.718 0.9994 1163438 ChemDiv1_005350 CCOc1ccccc1C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)cc5)C(=O)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D05 compound treatment 280.6 92.6 0.48 284.5 98.3 0.51 0.7029 0.9996 1928272 ChemDiv1_005351 [O-][N+](=O)c1ccc(cc1)C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D06 compound treatment 278.4 90.4 0.47 282.8 96.6 0.5 0.6886 0.9995 1972827 ChemDiv1_005352 [O-][N+](=O)c1cccc(c1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D07 compound treatment 280.1 92.1 0.48 286.6 100.0 0.52 0.7088 0.9991 1493908 ChemDiv1_005353 CCOc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)c3cn4ccccc4n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D08 compound treatment 277.6 89.6 0.47 286.2 100.0 0.52 0.6981 0.9986 1240853 ChemDiv1_005354 CN(C)c1ccc(cc1)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D09 compound treatment 278.7 90.7 0.47 280.9 94.7 0.49 0.6827 0.9998 1141789 ChemDiv1_005355 O=C(Nc1ccc(cc1)c2cn3ccccc3n2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D10 compound treatment 278.7 90.7 0.47 283.0 96.8 0.5 0.6904 0.9995 1972828 ChemDiv1_005356 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4cccc(O)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D11 compound treatment 278.4 90.4 0.47 284.9 98.7 0.51 0.6963 0.9991 1410001 ChemDiv1_005357 COc1ccc2c(C)nc(Nc3nc(O)c4ccccc4n3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D12 compound treatment 279.7 91.7 0.48 285.5 99.3 0.52 0.7033 0.9993 1972829 ChemDiv1_005358 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cc(OC)c(OC)c(OC)c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D13 compound treatment 285.2 97.2 0.51 282.1 95.9 0.5 0.7111 1.0 1670478 ChemDiv1_005359 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D14 compound treatment 277.3 89.3 0.47 279.7 93.5 0.49 0.6731 0.9998 1972830 ChemDiv1_005360 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D15 compound treatment 276.5 88.5 0.46 279.8 93.6 0.49 0.6705 0.9996 1549210 ChemDiv1_005361 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D16 compound treatment 282.5 94.5 0.49 280.7 94.5 0.49 0.696 1.0 1972831 ChemDiv1_005362 CCOc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D17 compound treatment 278.1 90.1 0.47 279.2 93.0 0.48 0.6742 0.9999 1436630 ChemDiv1_005363 COc1ccc2N(C(=O)c3sc4ccccc4c3Cl)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D18 compound treatment 276.5 88.5 0.46 279.9 93.7 0.49 0.6709 0.9996 1972832 ChemDiv1_005364 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5cccc(OC(=O)c6cccs6)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D19 compound treatment 279.4 91.4 0.48 280.8 94.6 0.49 0.6849 0.9999 1972833 ChemDiv1_005365 CCOc1ccc2nc(SCc3ccc(cc3)[N+](=O)[O-])nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D20 compound treatment 276.3 88.3 0.46 278.4 92.2 0.48 0.6647 0.9998 1972834 ChemDiv1_005366 Brc1ccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)nc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D21 compound treatment 282.2 94.2 0.49 276.6 90.4 0.47 0.6798 0.9998 1687575 ChemDiv1_005367 CC1CC(N(C(=O)c2cccc(C)c2)c3ccccc3)c4ccccc4N1C(=O)c5cccc(C)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D22 compound treatment 277.9 89.9 0.47 278.6 92.4 0.48 0.6713 0.9999 1213750 ChemDiv1_005368 COc1ccccc1C(=O)On2c(C)nc3ccccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D23 mock treatment 279.9 91.9 0.48 277.3 91.1 0.47 0.6739 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 D24 mock treatment 65.9 -122.0 -0.64 75.1 -111.0 -0.58 -0.8587 -0.9988 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E01 compound treatment 286.5 98.5 0.51 284.2 98.0 0.51 0.7236 1.0 1972835 ChemDiv1_005369 [O-][N+](=O)c1ccc2[nH]c(SCc3nc4sccn4c3Br)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E02 compound treatment 285.3 97.3 0.51 286.8 101.0 0.52 0.7287 0.9999 1710631 ChemDiv1_005370 CCOc1ccc(cc1)c2cc(C(=O)NCc3ccncc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E03 compound treatment 284.5 96.5 0.5 281.7 95.5 0.5 0.707 1.0 1419901 ChemDiv1_005371 COC(=O)c1ccc(NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3[nH]2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E04 compound treatment 281.3 93.3 0.49 284.0 97.8 0.51 0.7037 0.9998 1212138 ChemDiv1_005372 CCc1ccc(cc1)c2cc(C(=O)N3CCN(C)CC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E05 compound treatment 285.4 97.4 0.51 282.8 96.6 0.5 0.7144 1.0 1972836 ChemDiv1_005373 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E06 compound treatment 285.3 97.3 0.51 283.3 97.1 0.5 0.7159 1.0 1214468 ChemDiv1_005374 COc1cccc(c1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccc(C)n4)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E07 compound treatment 282.9 94.9 0.49 283.9 97.7 0.51 0.7092 0.9999 1204127 ChemDiv1_005375 COc1ccc(cc1)C2=NN(C(C2)c3cccs3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E08 compound treatment 278.7 90.7 0.47 284.0 97.8 0.51 0.6941 0.9993 1308765 ChemDiv1_005376 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E09 compound treatment 280.8 92.8 0.48 284.5 98.3 0.51 0.7037 0.9996 1718477 ChemDiv1_005377 O=c1c(=Cc2cccc(OCc3cccc4ccccc34)c2)sc5nc6ccccc6n15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E10 compound treatment 281.1 93.1 0.49 285.4 99.2 0.52 0.7081 0.9995 1972837 ChemDiv1_005378 CC(C)c1c(C#N)c(N)nc(SC2CC(=O)N(C2=O)c3ccccc3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E11 compound treatment 277.4 89.4 0.47 282.4 96.2 0.5 0.6834 0.9994 1294280 ChemDiv1_005379 CCCOc1ccc(cc1)c2cc(C(=O)NCC3CCCO3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E12 compound treatment 280.6 92.6 0.48 277.4 91.2 0.47 0.6768 1.0 1500031 ChemDiv1_005380 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c(CC)c(C)c3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E13 compound treatment 279.4 91.4 0.48 283.3 97.1 0.5 0.6941 0.9996 1249230 ChemDiv1_005381 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3ccccc23)c4ccc(C)cc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E14 compound treatment 277.5 89.5 0.47 276.0 89.8 0.47 0.6603 1.0 1972838 ChemDiv1_005382 Brc1ccc2NC(=O)C(=Cc3nc4ccccc4c(=O)n3Cc5ccccc5)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E15 compound treatment 279.9 91.9 0.48 279.1 92.9 0.48 0.6805 1.0 1472054 ChemDiv1_005383 COc1cccc(c1)c2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E16 compound treatment 279.3 91.3 0.48 274.9 88.7 0.46 0.6629 0.9999 1972839 ChemDiv1_005384 CC(C)N(C(=O)CN(C#N)c1nc(nc(n1)N(C)C)N(C)C)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E17 compound treatment 276.6 88.6 0.46 277.5 91.3 0.47 0.6625 0.9999 1305334 ChemDiv1_005385 COc1ccc(cc1)c2cc(C(=O)Nc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E18 compound treatment 279.0 91.0 0.47 273.8 87.6 0.46 0.6577 0.9998 1479396 ChemDiv1_005386 CCNc1nc(NC(C)C)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E19 compound treatment 280.6 92.6 0.48 276.5 90.3 0.47 0.6735 0.9999 1268825 ChemDiv1_005387 Cc1ccc(cc1)c2cc(C(=O)NCc3ccncc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E20 compound treatment 275.3 87.3 0.46 279.5 93.3 0.49 0.665 0.9995 1640185 ChemDiv1_005388 CCOC(=O)c1c(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)sc6CCC(C)Cc16 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E21 compound treatment 278.2 90.2 0.47 276.4 90.2 0.47 0.6643 1.0 1676670 ChemDiv1_005389 Brc1ccc(cc1)c2cc(C(=O)NCc3ccccn3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E22 compound treatment 274.4 86.4 0.45 275.3 89.1 0.46 0.6463 0.9999 1972840 ChemDiv1_005390 O=C1C2C3CC(C=C3)C2C(=O)N1CCCCCCN4C(=O)C5C6CC(C=C6)C5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E23 mock treatment 281.5 93.5 0.49 282.6 96.4 0.5 0.6993 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 E24 mock treatment 77.8 -110.0 -0.57 76.3 -110.0 -0.57 -0.8104 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F01 compound treatment 283.4 95.4 0.5 284.5 98.3 0.51 0.7133 0.9999 1972841 ChemDiv1_005391 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC(=O)c5ccc(Cl)cc5)n42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F02 compound treatment 283.7 95.7 0.5 287.0 101.0 0.52 0.7236 0.9997 1422452 ChemDiv1_005392 COc1ccc(cc1)C(=O)N2C(C)CC(N(C(=O)C)c3ccccc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F03 compound treatment 287.9 99.9 0.52 285.7 99.5 0.52 0.7343 1.0 1368257 ChemDiv1_005393 CC1(Cc2ccccc2-c3nc(SCC(=O)N)n(Cc4ccccc4)c(=O)c31)C5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F04 compound treatment 280.5 92.5 0.48 282.2 96.0 0.5 0.6941 0.9999 1381370 ChemDiv1_005394 CCCOc1ccccc1C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)cc5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F05 compound treatment 276.2 88.2 0.46 284.3 98.1 0.51 0.686 0.9987 1524648 ChemDiv1_005395 COc1cc(OC)c(cc1OC)C2SCCN2C(=O)c3cc4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F06 compound treatment 284.1 96.1 0.5 284.0 97.8 0.51 0.714 1.0 1740766 ChemDiv1_005396 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F07 compound treatment 282.2 94.2 0.49 284.1 97.9 0.51 0.7074 0.9998 1457235 ChemDiv1_005397 O=C(Nc1c(nc2ccccn12)c3ccccc3)c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F08 compound treatment 278.7 90.7 0.47 280.9 94.7 0.49 0.6827 0.9998 1972842 ChemDiv1_005398 NC1=C(C#N)C2(C(=O)Nc3ccc(F)cc32)c4c(n[nH]c4O1)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F09 compound treatment 274.6 86.6 0.45 282.2 96.0 0.5 0.6724 0.9988 1137033 ChemDiv1_005399 Cc1ccn2c(NC(=O)c3cc4cc(Br)ccc4oc3=O)c(nc2c1)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F10 compound treatment 282.4 94.4 0.49 284.4 98.2 0.51 0.7092 0.9998 1972843 ChemDiv1_005400 COc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F11 compound treatment 276.5 88.5 0.46 281.0 94.8 0.49 0.6749 0.9995 1776105 ChemDiv1_005401 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F12 compound treatment 276.9 88.9 0.46 284.4 98.2 0.51 0.6889 0.9988 1972844 ChemDiv1_005402 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cc(OC)c(OC)c(OC)c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F13 compound treatment 281.4 93.4 0.49 284.2 98.0 0.51 0.7048 0.9997 1551341 ChemDiv1_005403 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F14 compound treatment 279.4 91.4 0.48 280.3 94.1 0.49 0.6831 0.9999 1972845 ChemDiv1_005404 COc1cc(OC)c(C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F15 compound treatment 274.1 86.1 0.45 278.1 91.9 0.48 0.6554 0.9995 1972846 ChemDiv1_005405 COc1ccc2N(C(=O)CN3C(=O)C4CCCCC4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F16 compound treatment 303.5 115.0 0.6 306.2 120.0 0.62 0.8672 0.9998 1972847 ChemDiv1_005406 COc1cc(cc(OC)c1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F17 compound treatment 280.7 92.7 0.48 280.1 93.9 0.49 0.6871 1.0 1706222 ChemDiv1_005407 COc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4sc5ccccc5c4Cl)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F18 compound treatment 273.2 85.2 0.44 283.0 96.8 0.5 0.6701 0.9981 1972848 ChemDiv1_005408 COc1cccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c1OC(=O)N6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F19 compound treatment 278.8 90.8 0.47 280.2 94.0 0.49 0.6805 0.9999 1972849 ChemDiv1_005409 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F20 compound treatment 297.5 109.0 0.57 296.5 110.0 0.57 0.8094 1.0 1972850 ChemDiv1_005410 CC1(C)CC(=O)c2sc(NC(=O)/C=C\c3ccco3)nc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F21 compound treatment 274.9 86.9 0.45 277.0 90.8 0.47 0.6543 0.9998 1347210 ChemDiv1_005411 COc1ccc(cc1)C(=O)N(C2CC(C)N(C(=O)c3ccc(OC)cc3)c4ccccc24)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F22 compound treatment 278.6 90.6 0.47 278.1 91.9 0.48 0.672 1.0 1178279 ChemDiv1_005412 COc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F23 mock treatment 283.5 95.5 0.5 278.3 92.1 0.48 0.6908 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 F24 mock treatment 85.5 -103.0 -0.53 81.5 -105.0 -0.54 -0.7629 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G01 compound treatment 281.8 93.8 0.49 289.6 103.0 0.54 0.7261 0.9989 1869053 ChemDiv1_005413 Cc1csc2nc(CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])cn12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G02 compound treatment 284.3 96.3 0.5 281.9 95.7 0.5 0.707 1.0 1972851 ChemDiv1_005414 [O-][N+](=O)c1cc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)ccc1F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G03 compound treatment 284.1 96.1 0.5 280.5 94.3 0.49 0.7011 0.9999 1227987 ChemDiv1_005415 CC(C)N(C(=O)CSc1nc2n(C)c(=O)n(C)c(=O)c2[nH]1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G04 compound treatment 283.5 95.5 0.5 282.3 96.1 0.5 0.7055 1.0 1301368 ChemDiv1_005416 Cc1cccc(c1)c2cc(C(=O)Nc3ccc(cc3)C(=O)N)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G05 compound treatment 284.0 96.0 0.5 284.1 97.9 0.51 0.714 1.0 1972852 ChemDiv1_005417 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G06 compound treatment 284.8 96.8 0.5 282.2 96.0 0.5 0.71 1.0 1333118 ChemDiv1_005418 Clc1ccccc1c2cc(C(=O)Nc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G07 compound treatment 283.3 95.3 0.5 282.0 95.8 0.5 0.7037 1.0 1972853 ChemDiv1_005419 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G08 compound treatment 281.2 93.2 0.49 285.3 99.1 0.52 0.7081 0.9996 1722193 ChemDiv1_005420 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G09 compound treatment 284.9 96.9 0.51 287.1 101.0 0.52 0.7284 0.9998 1972854 ChemDiv1_005421 CCOc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccccc3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G10 compound treatment 281.0 93.0 0.49 283.5 97.3 0.51 0.7007 0.9998 1972855 ChemDiv1_005422 COc1ccc(cc1)N2C(=O)CC(Sc3nc(N)c(C#N)c(c3C#N)c4ccc(C)cc4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G11 compound treatment 280.9 92.9 0.48 283.0 96.8 0.5 0.6985 0.9998 1676666 ChemDiv1_005423 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3sc4cc(C)ccc4c3Cl)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G12 compound treatment 283.8 95.8 0.5 288.2 102.0 0.53 0.7283 0.9996 1972856 ChemDiv1_005424 O=C1CC(Sc2nc(ccc2C#N)c3ccccc3)C(=O)N1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G13 compound treatment 282.1 94.1 0.49 283.2 97.0 0.5 0.7037 0.9999 1158835 ChemDiv1_005425 CCOC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)N)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G14 compound treatment 278.8 90.8 0.47 281.4 95.2 0.5 0.6849 0.9998 1972857 ChemDiv1_005426 CN1C(=O)C(=Cc2nc3ccccc3c(=O)n2Cc4ccccc4)c5cc(Br)ccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G15 compound treatment 282.5 94.5 0.49 282.2 96.0 0.5 0.7015 1.0 1972858 ChemDiv1_005427 Cc1ccc(s1)c2cc(C(=O)Nc3ccc(F)c(c3)[N+](=O)[O-])c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G16 compound treatment 279.9 91.9 0.48 284.6 98.4 0.51 0.7007 0.9995 1972859 ChemDiv1_005428 CN(C)c1nc(nc(n1)N2CC(=O)N(C2=N)c3ccc(Cl)cc3)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G17 compound treatment 277.3 89.3 0.47 278.3 92.1 0.48 0.668 0.9999 1529812 ChemDiv1_005429 CCN(CC)C(=O)c1cc(nc2ccccc12)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G18 compound treatment 284.0 96.0 0.5 282.5 96.3 0.5 0.7081 1.0 1424874 ChemDiv1_005430 COC(=O)COC(=O)c1ccc(Oc2nc(NC(C)C)nc(NC(C)C)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G19 compound treatment 281.2 93.2 0.49 282.5 96.3 0.5 0.6978 0.9999 1704737 ChemDiv1_005431 COc1ccc(cc1)c2cc(C(=O)Nc3sc(C)c(C)c3C(=O)N)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G20 compound treatment 277.2 89.2 0.47 279.8 93.6 0.49 0.6731 0.9997 1972860 ChemDiv1_005432 O=C(Nc1sc2CCCCc2c1C#N)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G21 compound treatment 278.6 90.6 0.47 279.8 93.6 0.49 0.6783 0.9999 1403754 ChemDiv1_005433 COC(=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccc(C)s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G22 compound treatment 278.0 90.0 0.47 272.9 86.7 0.45 0.6507 0.9998 1303203 ChemDiv1_005434 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G23 mock treatment 284.4 96.4 0.5 276.0 89.8 0.47 0.6857 0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 G24 mock treatment 76.4 -112.0 -0.58 79.0 -107.0 -0.56 -0.8056 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H01 compound treatment 282.3 94.3 0.49 284.2 98.0 0.51 0.7081 0.9998 1972861 ChemDiv1_005435 CC1(C)Cc2c(CO1)sc3[nH]c(=S)n(c4ccc(Br)cc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H02 compound treatment 286.9 98.9 0.52 283.1 96.9 0.5 0.721 0.9999 1872587 ChemDiv1_005436 CC1CC(N(C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)c4ccccc4N1C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H03 compound treatment 284.5 96.5 0.5 283.4 97.2 0.51 0.7133 1.0 1932257 ChemDiv1_005437 CON(C)c1nc(OCCNC(=O)COc2ccc(Cl)cc2Cl)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H04 compound treatment 281.5 93.5 0.49 280.3 94.1 0.49 0.6908 1.0 1972862 ChemDiv1_005438 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H05 compound treatment 283.4 95.4 0.5 282.1 95.9 0.5 0.7044 1.0 1463157 ChemDiv1_005439 Clc1ccccc1C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H06 compound treatment 284.2 96.2 0.5 280.8 94.6 0.49 0.7026 1.0 1972863 ChemDiv1_005440 CC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H07 compound treatment 279.3 91.3 0.48 279.5 93.3 0.49 0.6798 1.0 1723703 ChemDiv1_005441 COc1cccc(c1)C(=O)Nc2c(nc3cc(C)ccn23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H08 compound treatment 281.1 93.1 0.49 284.3 98.1 0.51 0.704 0.9997 1972864 ChemDiv1_005442 CCc1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H09 compound treatment 280.6 92.6 0.48 279.5 93.3 0.49 0.6846 1.0 1972865 ChemDiv1_005443 Cc1ccn2cc(nc2c1)c3cccc(NC(=O)/C=C\C(=O)O)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H10 compound treatment 279.5 91.5 0.48 284.6 98.4 0.51 0.6992 0.9994 1972866 ChemDiv1_005444 COc1ccccc1C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H11 compound treatment 280.6 92.6 0.48 281.0 94.8 0.49 0.6901 0.9999 1536947 ChemDiv1_005445 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H12 compound treatment 283.6 95.6 0.5 280.6 94.4 0.49 0.6997 1.0 1972867 ChemDiv1_005446 COc1cc(cc(OC)c1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cc(OC)c(OC)c(OC)c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H13 compound treatment 276.3 88.3 0.46 282.9 96.7 0.5 0.6812 0.999 1541600 ChemDiv1_005447 COc1ccc(cc1)C(=O)N2C(C)CC(Nc3ccc(C)cc3)c4cc(C)ccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H14 compound treatment 281.3 93.3 0.49 282.5 96.3 0.5 0.6982 0.9999 1972868 ChemDiv1_005448 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H15 compound treatment 274.8 86.8 0.45 279.2 93.0 0.48 0.6621 0.9995 1972869 ChemDiv1_005449 CCOc1ccc2N(C(=O)CN3C(=O)C4CCCCC4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H16 compound treatment 276.0 88.0 0.46 282.2 96.0 0.5 0.6775 0.9991 1972870 ChemDiv1_005450 COc1cccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H17 compound treatment 282.4 94.4 0.49 279.0 92.8 0.48 0.6894 1.0 1285771 ChemDiv1_005451 COc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4sc5ccccc5c4Cl)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H18 compound treatment 280.4 92.4 0.48 280.7 94.5 0.49 0.6882 1.0 1972871 ChemDiv1_005452 COc1cc(ccc1OC(=O)c2ccco2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H19 compound treatment 279.4 91.4 0.48 276.0 89.8 0.47 0.6673 0.9999 1501502 ChemDiv1_005453 Cc1ccc2N(C(=O)CSc3nncn3C)C(C)(C)CC(C)(c4ccccc4)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H20 compound treatment 278.9 90.9 0.47 279.2 93.0 0.48 0.6772 1.0 1290704 ChemDiv1_005454 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H21 compound treatment 278.9 90.9 0.47 275.9 89.7 0.47 0.6651 1.0 1377902 ChemDiv1_005455 CC1CC(N(C(=O)c2cccc(Br)c2)c3ccccc3)c4ccccc4N1C(=O)c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H22 compound treatment 282.5 94.5 0.49 279.4 93.2 0.48 0.6912 1.0 1478471 ChemDiv1_005456 Fc1ccccc1C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H23 mock treatment 279.1 91.1 0.48 279.3 93.1 0.48 0.6783 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 H24 mock treatment 78.0 -110.0 -0.57 78.9 -107.0 -0.56 -0.8001 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I01 compound treatment 285.1 97.1 0.51 287.0 101.0 0.52 0.7287 0.9999 1972872 ChemDiv1_005457 Cc1csc2nc(CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])c(Br)n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I02 compound treatment 282.8 94.8 0.49 287.0 101.0 0.52 0.7202 0.9996 1245911 ChemDiv1_005458 CCc1ccc(cc1)c2cc(C(=O)NCc3ccncc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I03 compound treatment 278.6 90.6 0.47 283.5 97.3 0.51 0.6919 0.9994 1701313 ChemDiv1_005459 CCOc1ccc2nc(NC(=O)C3CC(=CCC3C(=O)O)C)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I04 compound treatment 286.3 98.3 0.51 283.9 97.7 0.51 0.7218 1.0 1949458 ChemDiv1_005460 COc1ccc(cc1)c2nc3ccccc3c(C(=O)Nc4ccc(cc4)C(=O)C)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I05 compound treatment 282.6 94.6 0.49 283.3 97.1 0.5 0.7059 0.9999 1972873 ChemDiv1_005461 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccccc3CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I06 compound treatment 281.8 93.8 0.49 283.2 97.0 0.5 0.7026 0.9999 1296184 ChemDiv1_005462 Cc1ccc(c(C)c1)c2cc(C(=O)NCC3CCCO3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I07 compound treatment 278.4 90.4 0.47 281.5 95.3 0.5 0.6838 0.9997 1582790 ChemDiv1_005463 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I08 compound treatment 281.9 93.9 0.49 281.4 95.2 0.5 0.6963 1.0 1619900 ChemDiv1_005464 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCCc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I09 compound treatment 291.7 104.0 0.54 297.0 111.0 0.58 0.7898 0.9995 1972874 ChemDiv1_005465 CC(C)(C)c1ccc(OCCOc2ccc(/C=C\3/NC(=S)NC3=O)cc2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I10 compound treatment 284.2 96.2 0.5 288.5 102.0 0.53 0.7309 0.9996 1237419 ChemDiv1_005466 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(Cl)cc3Cl)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I11 compound treatment 284.0 96.0 0.5 278.8 92.6 0.48 0.6945 0.9998 1972875 ChemDiv1_005467 COc1ccc(cc1OC)c2cc(C(=O)Nc3cccc(c3)[N+](=O)[O-])c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I12 compound treatment 283.5 95.5 0.5 284.3 98.1 0.51 0.7129 0.9999 1565271 ChemDiv1_005468 Cc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I13 compound treatment 280.7 92.7 0.48 283.4 97.2 0.51 0.6993 0.9998 1972876 ChemDiv1_005469 CCOc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(C)s4)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I14 compound treatment 295.0 107.0 0.56 289.8 104.0 0.54 0.7755 0.9998 1972877 ChemDiv1_005470 OC(=O)c1ccc(cc1)n2c(/C=C\c3cc(Br)ccc3O)nc4ccccc4c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I15 compound treatment 277.3 89.3 0.47 288.5 102.0 0.53 0.7055 0.9978 1388193 ChemDiv1_005471 CCc1ccc(cc1)c2cc(C(=O)NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I16 compound treatment 280.1 92.1 0.48 282.9 96.7 0.5 0.6952 0.9997 1931352 ChemDiv1_005472 CC1N(C(=N)N(C1=O)c2ccc(Cl)c(Cl)c2)c3nc(nc(n3)N(C)C)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I17 compound treatment 279.1 91.1 0.48 283.5 97.3 0.51 0.6937 0.9995 1555030 ChemDiv1_005473 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4cc(C)nc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I18 compound treatment 279.1 91.1 0.48 283.3 97.1 0.5 0.693 0.9995 1946133 ChemDiv1_005474 Cn1cc(/C=C/c2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I19 compound treatment 279.2 91.2 0.48 278.1 91.9 0.48 0.6742 1.0 1412115 ChemDiv1_005475 Cc1c(nc2ccccc2c1C(=O)NCCN3CCOCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I20 compound treatment 278.6 90.6 0.47 277.6 91.4 0.48 0.6702 1.0 1972878 ChemDiv1_005476 CC1CCc2sc(NC(=O)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O)c(C#N)c2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I21 compound treatment 281.3 93.3 0.49 283.4 97.2 0.51 0.7015 0.9998 1972879 ChemDiv1_005477 CC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I22 compound treatment 280.4 92.4 0.48 277.8 91.6 0.48 0.6776 1.0 1435974 ChemDiv1_005478 CCCN(c1nc(C)c(Br)c(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I23 mock treatment 278.8 90.8 0.47 274.6 88.4 0.46 0.6599 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 I24 mock treatment 74.9 -113.0 -0.59 82.5 -104.0 -0.54 -0.7983 -0.999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J01 compound treatment 282.9 94.9 0.49 286.2 100.0 0.52 0.7177 0.9997 1972880 ChemDiv1_005479 CCC1(C)Cc2c(CO1)sc3[nH]c(=S)n(c4ccc(OC)cc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J02 compound treatment 283.8 95.8 0.5 285.2 99.0 0.51 0.7173 0.9999 1972881 ChemDiv1_005480 CCOC(=O)CC(=O)CSc1nc(C)c2cc(C)c(C)cc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J03 compound treatment 280.9 92.9 0.48 285.1 98.9 0.51 0.7062 0.9996 1932201 ChemDiv1_005481 CON(C)c1nc(OCCNC(=O)COc2ccc(Cl)cc2C)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J04 compound treatment 280.7 92.7 0.48 284.7 98.5 0.51 0.704 0.9996 1730756 ChemDiv1_005482 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J05 compound treatment 279.8 91.8 0.48 277.8 91.6 0.48 0.6754 1.0 1695143 ChemDiv1_005483 CN(C)c1ccc(cc1)C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J06 compound treatment 280.2 92.2 0.48 289.8 104.0 0.54 0.7209 0.9984 1972882 ChemDiv1_005484 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J07 compound treatment 281.3 93.3 0.49 283.1 96.9 0.5 0.7004 0.9998 1972883 ChemDiv1_005485 Cc1ccn2c(NC(=O)c3cccc(c3)[N+](=O)[O-])c(nc2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J08 compound treatment 267.1 79.1 0.41 268.9 82.7 0.43 0.5958 0.9998 1972884 ChemDiv1_005486 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J09 compound treatment 276.9 88.9 0.46 280.4 94.2 0.49 0.6742 0.9996 1972885 ChemDiv1_005487 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)Nc2cccc(c2)c3cn4ccccc4n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J10 compound treatment 277.3 89.3 0.47 281.4 95.2 0.5 0.6794 0.9995 1972886 ChemDiv1_005488 CCOc1ccccc1C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J11 compound treatment 280.4 92.4 0.48 280.8 94.6 0.49 0.6886 0.9999 1430400 ChemDiv1_005489 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J12 compound treatment 278.4 90.4 0.47 283.0 96.8 0.5 0.6893 0.9995 1972887 ChemDiv1_005490 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c4cccs4)c23)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J13 compound treatment 276.1 88.1 0.46 285.3 99.1 0.52 0.6893 0.9984 1255655 ChemDiv1_005491 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)CN4C(=O)c5ccccc5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J14 compound treatment 279.3 91.3 0.48 282.4 96.2 0.5 0.6904 0.9997 1972888 ChemDiv1_005492 COc1cc(ccc1OC(=O)c2cccs2)C3C(=C(N)Oc4[nH]nc(c34)c5cccc(c5)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J15 compound treatment 276.8 88.8 0.46 275.7 89.5 0.47 0.6566 1.0 1940534 ChemDiv1_005493 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)C5CCCCC5C4=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J16 compound treatment 275.3 87.3 0.46 280.1 93.9 0.49 0.6672 0.9994 1972889 ChemDiv1_005494 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J17 compound treatment 278.1 90.1 0.47 278.8 92.6 0.48 0.6728 0.9999 1487260 ChemDiv1_005495 Cn1cnnc1SCC(=O)N2c3ccccc3-c4c(ssc4=S)C2(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J18 compound treatment 277.3 89.3 0.47 283.7 97.5 0.51 0.6878 0.9991 1972890 ChemDiv1_005496 COc1cc(ccc1OC(=O)c2cccs2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J19 compound treatment 280.2 92.2 0.48 279.6 93.4 0.49 0.6835 1.0 1972891 ChemDiv1_005497 CCc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)c3sc4cc(ccc4c3Cl)[N+](=O)[O-])c5ccccc52 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J20 compound treatment 281.0 93.0 0.49 276.7 90.5 0.47 0.6757 0.9999 1972892 ChemDiv1_005498 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J21 compound treatment 281.4 93.4 0.49 277.6 91.4 0.48 0.6805 0.9999 1972893 ChemDiv1_005499 CCCc1ccc(cc1)C(=O)N2C(C)CC(N(C(=O)c3ccc(cc3)[N+](=O)[O-])c4ccccc4)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J22 compound treatment 277.1 89.1 0.46 279.3 93.1 0.48 0.6709 0.9998 1972894 ChemDiv1_005500 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)C4CCCCC4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J23 mock treatment 279.7 91.7 0.48 280.4 94.2 0.49 0.6845 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 J24 mock treatment 84.1 -104.0 -0.54 75.9 -110.0 -0.57 -0.7886 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K01 compound treatment 288.2 100.0 0.52 287.1 101.0 0.52 0.7405 1.0 1972895 ChemDiv1_005501 [O-][N+](=O)c1ccc2sc(SCc3nc4ncccn4c3Br)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K02 compound treatment 283.1 95.1 0.5 281.8 95.6 0.5 0.7022 1.0 1271912 ChemDiv1_005502 Cc1cccc(c1)c2cc(C(=O)NCc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K03 compound treatment 282.5 94.5 0.49 278.8 92.6 0.48 0.689 0.9999 1573066 ChemDiv1_005503 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCCCC4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K04 compound treatment 284.2 96.2 0.5 283.0 96.8 0.5 0.7107 1.0 1242495 ChemDiv1_005504 CCOC(=O)c1c(NC(=O)c2sc3ccccc3c2Cl)sc4CC(CCc14)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K05 compound treatment 281.9 93.9 0.49 281.2 95.0 0.49 0.6956 1.0 1926817 ChemDiv1_005505 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K06 compound treatment 280.8 92.8 0.48 289.6 103.0 0.54 0.7224 0.9986 1528898 ChemDiv1_005506 Clc1ccccc1c2cc(C(=O)NCc3ccccn3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K07 compound treatment 291.3 103.0 0.54 292.0 106.0 0.55 0.77 0.9999 1972896 ChemDiv1_005507 CCOc1ccc2cc(C3=NN(C(C3)c4ccc(C)cc4)C(=O)CCC(=O)O)c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K08 compound treatment 281.1 93.1 0.49 283.2 97.0 0.5 0.7 0.9998 1193279 ChemDiv1_005508 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCC(C)Cc4cc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K09 compound treatment 281.4 93.4 0.49 282.4 96.2 0.5 0.6982 0.9999 1157191 ChemDiv1_005509 CCOC(=O)c1c(NC(=O)c2sc3cc(F)ccc3c2Cl)scc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K10 compound treatment 280.0 92.0 0.48 276.7 90.5 0.47 0.6721 1.0 1972897 ChemDiv1_005510 Cc1nc(SC2CC(=O)N(C2=O)c3ccc(Br)cc3)c(C#N)c(C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K11 compound treatment 279.3 91.3 0.48 282.4 96.2 0.5 0.6904 0.9997 1373098 ChemDiv1_005511 COc1ccc(cc1OC)c2cc(C(=O)Nc3cc(C)on3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K12 compound treatment 278.0 90.0 0.47 280.2 94.0 0.49 0.6775 0.9998 1434985 ChemDiv1_005512 OCCN1CCN(CC1)c2nc(nc(n2)N3CCCCC3)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K13 compound treatment 281.8 93.8 0.49 281.5 95.3 0.5 0.6963 1.0 1541895 ChemDiv1_005513 COc1ccccc1N2CCN(CC2)C(=O)c3cc(nc4ccccc34)c5ccc(C)s5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K14 compound treatment 275.9 87.9 0.46 278.0 91.8 0.48 0.6617 0.9998 1933528 ChemDiv1_005514 CC(C)C1(CN2CC3(CN(C1)C24C(=O)Nc5ccccc54)C(C)C)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K15 compound treatment 279.8 91.8 0.48 284.8 98.6 0.51 0.7011 0.9994 1481547 ChemDiv1_005515 Cc1c(nc2ccccc2c1C(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K16 compound treatment 286.8 98.8 0.52 284.8 98.6 0.51 0.7269 1.0 1972898 ChemDiv1_005516 COc1nc(nc(n1)N2C(C)C(=O)N(C2=N)c3ccc(Cl)c(Cl)c3)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K17 compound treatment 279.4 91.4 0.48 281.1 94.9 0.49 0.686 0.9998 1972899 ChemDiv1_005517 Cc1ccc(s1)c2cc(C(=O)NCCCn3ccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K18 compound treatment 278.9 90.9 0.47 278.3 92.1 0.48 0.6739 1.0 1972900 ChemDiv1_005518 CN1C(=O)C(=Cc2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])c5cc(Br)ccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K19 compound treatment 277.6 89.6 0.47 282.2 96.0 0.5 0.6834 0.9995 1716304 ChemDiv1_005519 Clc1ccc(cc1Cl)c2cc(C(=O)N3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K20 compound treatment 281.4 93.4 0.49 276.7 90.5 0.47 0.6772 0.9999 1351102 ChemDiv1_005520 CCOC(=O)c1c(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)sc6CCCCc16 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K21 compound treatment 276.2 88.2 0.46 278.2 92.0 0.48 0.6636 0.9998 1357909 ChemDiv1_005521 CCOC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)c(OC)c4)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K22 compound treatment 279.9 91.9 0.48 280.4 94.2 0.49 0.6853 0.9999 1575220 ChemDiv1_005522 CCCN(c1nc(C)c(Cl)c(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K23 mock treatment 283.9 95.9 0.5 277.0 90.8 0.47 0.6875 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 K24 mock treatment 81.8 -106.0 -0.55 78.9 -107.0 -0.56 -0.7861 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L01 compound treatment 285.0 97.0 0.51 287.0 101.0 0.52 0.7284 0.9998 1972901 ChemDiv1_005523 CCC1(C)Cc2c(CO1)sc3nc(SC)n(c4ccc(OC)cc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L02 compound treatment 282.2 94.2 0.49 279.0 92.8 0.48 0.6886 1.0 1972902 ChemDiv1_005524 COc1ccc(Nc2nc(Cl)nc(Nc3cccc(c3)[N+](=O)[O-])n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L03 compound treatment 284.9 96.9 0.51 285.0 98.8 0.51 0.7206 1.0 1257403 ChemDiv1_005525 Cc1sc(NC(=O)c2cc3cc(Br)ccc3oc2=O)nc1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L04 compound treatment 283.9 95.9 0.5 284.2 98.0 0.51 0.714 1.0 1972903 ChemDiv1_005526 COc1ccc(cc1OC)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C4)c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L05 compound treatment 280.7 92.7 0.48 284.6 98.4 0.51 0.7037 0.9996 1233432 ChemDiv1_005527 Cc1nc(cs1)c2ccc(NC(=O)c3cc4cc(Br)ccc4oc3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L06 compound treatment 283.3 95.3 0.5 285.0 98.8 0.51 0.7147 0.9999 1972904 ChemDiv1_005528 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L07 compound treatment 281.1 93.1 0.49 283.3 97.1 0.5 0.7004 0.9998 1784263 ChemDiv1_005529 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2c(nc3ccccn23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L08 compound treatment 281.0 93.0 0.49 285.6 99.4 0.52 0.7085 0.9995 1972905 ChemDiv1_005530 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L09 compound treatment 281.4 93.4 0.49 285.2 99.0 0.51 0.7085 0.9996 1572388 ChemDiv1_005531 O=S(=O)(Nc1cccc(c1)c2cn3ccccc3n2)c4ccc5ccccc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L10 compound treatment 306.1 118.0 0.62 303.6 117.0 0.61 0.8672 1.0 1972906 ChemDiv1_005532 COc1cc(cc(OC)c1O)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L11 compound treatment 276.9 88.9 0.46 277.7 91.5 0.48 0.6643 0.9999 1216629 ChemDiv1_005533 CC1CC(N(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc4)c5ccccc5N1C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L12 compound treatment 281.5 93.5 0.49 282.9 96.7 0.5 0.7004 0.9999 1972907 ChemDiv1_005534 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4cc(Br)ccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L13 compound treatment 280.1 92.1 0.48 280.1 93.9 0.49 0.6849 1.0 1170338 ChemDiv1_005535 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)COc4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L14 compound treatment 278.7 90.7 0.47 281.6 95.4 0.5 0.6853 0.9997 1972908 ChemDiv1_005536 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cccc(c5)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L15 compound treatment 279.6 91.6 0.48 279.3 93.1 0.48 0.6801 1.0 1972909 ChemDiv1_005537 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)C4CCCCC4C3=O)c5ccccc25)S1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L16 compound treatment 276.4 88.4 0.46 284.9 98.7 0.51 0.6889 0.9986 1972910 ChemDiv1_005538 COc1ccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L17 compound treatment 275.3 87.3 0.46 283.7 97.5 0.51 0.6804 0.9986 1289799 ChemDiv1_005539 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CSc4nc5ccccc5o4)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L18 compound treatment 286.2 98.2 0.51 280.3 94.1 0.49 0.7082 0.9997 1972911 ChemDiv1_005540 CCOc1cc(ccc1OC(=O)c2ccco2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L19 compound treatment 278.5 90.5 0.47 279.0 92.8 0.48 0.675 0.9999 1366937 ChemDiv1_005541 CC1CC(N(C(=O)c2ccc(Cl)cc2)c3ccccc3)c4ccccc4N1C(=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L20 compound treatment 275.5 87.5 0.46 278.0 91.8 0.48 0.6602 0.9997 1371364 ChemDiv1_005542 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Br)ccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L21 compound treatment 279.0 91.0 0.47 277.8 91.6 0.48 0.6724 1.0 1972912 ChemDiv1_005543 CCCCCC(=O)N(C1CC(C)N(C(=O)c2cccc(OC)c2)c3ccccc13)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L22 compound treatment 277.6 89.6 0.47 279.1 92.9 0.48 0.672 0.9999 1157436 ChemDiv1_005544 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L23 mock treatment 280.6 92.6 0.48 281.1 94.9 0.49 0.6904 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 L24 mock treatment 81.0 -107.0 -0.56 76.2 -110.0 -0.57 -0.7989 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M01 compound treatment 285.3 97.3 0.51 287.1 101.0 0.52 0.7298 0.9999 1972913 ChemDiv1_005545 Cc1csc2nc(CSc3nc4cc(ccc4s3)[N+](=O)[O-])c(Br)n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M02 compound treatment 283.4 95.4 0.5 283.8 97.6 0.51 0.7107 1.0 1247316 ChemDiv1_005546 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)c(Cl)c4)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M03 compound treatment 279.6 91.6 0.48 282.5 96.3 0.5 0.6919 0.9997 1972914 ChemDiv1_005547 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CNCCO)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M04 compound treatment 280.0 92.0 0.48 282.1 95.9 0.5 0.6919 0.9998 1198463 ChemDiv1_005548 CCN(CC)C(=O)c1sc(NC(=O)c2c(C)onc2c3ccccc3Cl)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M05 compound treatment 301.2 113.0 0.59 305.1 119.0 0.62 0.8546 0.9997 1972915 ChemDiv1_005549 Clc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M06 compound treatment 285.4 97.4 0.51 283.8 97.6 0.51 0.7181 1.0 1236558 ChemDiv1_005550 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M07 compound treatment 280.7 92.7 0.48 283.6 97.4 0.51 0.7 0.9997 1701106 ChemDiv1_005551 CCOc1ccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(Cl)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M08 compound treatment 284.2 96.2 0.5 277.9 91.7 0.48 0.692 0.9997 1972916 ChemDiv1_005552 COc1ccc(cc1)N2C(=O)CC(Sc3nc(N)c(C#N)c(c3C#N)c4ccccc4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M09 compound treatment 282.1 94.1 0.49 283.7 97.5 0.51 0.7055 0.9999 1714671 ChemDiv1_005553 CCOc1cccc(c1)c2cc(C(=O)Nc3cc(C)on3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M10 compound treatment 281.9 93.9 0.49 284.9 98.7 0.51 0.7092 0.9997 1584909 ChemDiv1_005554 O=C1CC(Sc2nc3CCCCCc3cc2C#N)C(=O)N1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M11 compound treatment 285.2 97.2 0.51 277.3 91.1 0.47 0.6934 0.9994 1242438 ChemDiv1_005555 O=C(Nc1ccc2OCOc2c1)c3cc(nc4ccccc34)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M12 compound treatment 281.7 93.7 0.49 283.6 97.4 0.51 0.7037 0.9998 1972917 ChemDiv1_005556 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCSc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M13 compound treatment 281.6 93.6 0.49 281.9 95.7 0.5 0.6971 1.0 1643117 ChemDiv1_005557 Clc1ccc(cc1)c2cc(C(=O)N3CCCCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M14 compound treatment 286.9 98.9 0.52 280.2 94.0 0.49 0.7104 0.9996 1972918 ChemDiv1_005558 Brc1ccc(cc1)n2c(C=C3C(=O)Nc4ccccc34)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M15 compound treatment 278.9 90.9 0.47 272.3 86.1 0.45 0.6518 0.9996 1972919 ChemDiv1_005559 COc1cccc(c1)c2cc(C(=O)NCCCn3ccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M16 compound treatment 280.2 92.2 0.48 279.7 93.5 0.49 0.6838 1.0 1309660 ChemDiv1_005560 CCNc1nc(NC(C)CC)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M17 compound treatment 282.4 94.4 0.49 277.6 91.4 0.48 0.6842 0.9998 1631818 ChemDiv1_005561 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccc3F)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M18 compound treatment 279.2 91.2 0.48 275.1 88.9 0.46 0.6632 0.9999 1972920 ChemDiv1_005562 CC1(C)Cc2c(C#N)c(NC(=O)CN3C(=O)C4CC=C(Cl)CC4C3=O)sc2CO1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M19 compound treatment 282.0 94.0 0.49 277.3 91.1 0.47 0.6816 0.9999 1594627 ChemDiv1_005563 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M20 compound treatment 275.7 87.7 0.46 279.9 93.7 0.49 0.668 0.9995 1972921 ChemDiv1_005564 O=C(Nc1cccc2ccccc12)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M21 compound treatment 280.1 92.1 0.48 279.8 93.6 0.49 0.6838 1.0 1972922 ChemDiv1_005565 [O-][N+](=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M22 compound treatment 279.9 91.9 0.48 279.2 93.0 0.48 0.6809 1.0 1609074 ChemDiv1_005566 CCCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccccc2Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M23 mock treatment 280.3 92.3 0.48 275.1 88.9 0.46 0.6673 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 M24 mock treatment 192.2 4.18 0.02 193.5 7.34 0.04 0.0424 0.9648 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N01 compound treatment 280.2 92.2 0.48 286.0 99.8 0.52 0.707 0.9993 1972923 ChemDiv1_005567 CCOC(=O)CSc1nc2sc3COC(C)(CC)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N02 compound treatment 284.9 96.9 0.51 282.8 96.6 0.5 0.7126 1.0 1418520 ChemDiv1_005568 COc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c4ccccc4n3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N03 compound treatment 283.5 95.5 0.5 278.5 92.3 0.48 0.6916 0.9998 1534034 ChemDiv1_005569 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3cccc(c3)c4cn5ccccc5n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N04 compound treatment 283.3 95.3 0.5 286.0 99.8 0.52 0.7184 0.9998 1972924 ChemDiv1_005570 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N05 compound treatment 284.8 96.8 0.5 284.1 97.9 0.51 0.717 1.0 1657316 ChemDiv1_005571 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3ccc(cc3)c4cn5ccccc5n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N06 compound treatment 280.0 92.0 0.48 283.1 96.9 0.5 0.6956 0.9997 1785310 ChemDiv1_005572 CC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N07 compound treatment 277.0 89.0 0.46 279.3 93.1 0.48 0.6705 0.9998 1784264 ChemDiv1_005573 Cc1ccn2c(NC(=O)c3ccc(cc3)[N+](=O)[O-])c(nc2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N08 compound treatment 281.8 93.8 0.49 284.2 98.0 0.51 0.7063 0.9998 1972925 ChemDiv1_005574 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4cccc(Br)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N09 compound treatment 283.7 95.7 0.5 282.7 96.5 0.5 0.7078 1.0 1271696 ChemDiv1_005575 Cc1nc(sc1C(=O)Nc2ccc(cc2)c3cn4ccccc4n3)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N10 compound treatment 285.6 97.6 0.51 282.3 96.1 0.5 0.7133 1.0 1972926 ChemDiv1_005576 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N11 compound treatment 279.5 91.5 0.48 281.4 95.2 0.5 0.6875 0.9998 1972927 ChemDiv1_005577 CCCCCC(=O)N1C(C)CC(N(C(=O)c2cccc(OC)c2)c3ccccc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N12 compound treatment 278.8 90.8 0.47 279.6 93.4 0.49 0.6783 0.9999 1972928 ChemDiv1_005578 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4ccccc4C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N13 compound treatment 282.2 94.2 0.49 278.0 91.8 0.48 0.6849 0.9999 1972929 ChemDiv1_005579 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CSc3nc4ccccc4o3)c5ccc(OC)cc25)S1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N14 compound treatment 282.2 94.2 0.49 282.5 96.3 0.5 0.7015 1.0 1972930 ChemDiv1_005580 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccccc5Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N15 compound treatment 282.4 94.4 0.49 275.4 89.2 0.46 0.6761 0.9996 1972931 ChemDiv1_005581 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)C4CCCCC4C3=O)c5cc(C)ccc25)S1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N16 compound treatment 279.3 91.3 0.48 279.8 93.6 0.49 0.6809 0.9999 1972932 ChemDiv1_005582 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N17 compound treatment 275.5 87.5 0.46 277.7 91.5 0.48 0.6591 0.9998 1330507 ChemDiv1_005583 Cc1cc(C)c2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N18 compound treatment 280.2 92.2 0.48 279.0 92.8 0.48 0.6812 1.0 1541812 ChemDiv1_005584 CCC(Sc1nc2ccccc2o1)C(=O)Nc3ccc(Cl)cn3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N19 compound treatment 277.2 89.2 0.47 279.3 93.1 0.48 0.6713 0.9998 1946567 ChemDiv1_005585 COc1ccc2nc(NC3=NC(CC(=O)N3)c4ccccc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N20 compound treatment 279.2 91.2 0.48 278.3 92.1 0.48 0.675 1.0 1972933 ChemDiv1_005586 [O-][N+](=O)c1cc(C(=O)Nn2c(nc3ccccc3c2=O)C4CCCCC4)c(Cl)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N21 compound treatment 278.3 90.3 0.47 279.8 93.6 0.49 0.6772 0.9999 1283410 ChemDiv1_005587 COc1ccc(OCC(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N22 compound treatment 276.0 88.0 0.46 277.5 91.3 0.47 0.6602 0.9999 1333556 ChemDiv1_005588 Fc1ccccc1c2nc3ccccc3c(=O)n2NC(=O)c4cc5ccccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N23 mock treatment 279.6 91.6 0.48 277.0 90.8 0.47 0.6717 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 N24 mock treatment 196.8 8.78 0.05 191.7 5.54 0.03 0.0527 0.975 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O01 compound treatment 284.1 96.1 0.5 284.3 98.1 0.51 0.7151 1.0 1972934 ChemDiv1_005589 Cc1cccc2nc(CSc3nc4cc(ccc4o3)[N+](=O)[O-])c(Br)n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O02 compound treatment 292.2 104.0 0.54 295.1 109.0 0.57 0.7847 0.9998 1507899 ChemDiv1_005590 Brc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccco4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O03 compound treatment 282.6 94.6 0.49 281.1 94.9 0.49 0.6978 1.0 1370080 ChemDiv1_005591 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccc(F)cc4F)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O04 compound treatment 282.0 94.0 0.49 282.1 95.9 0.5 0.6993 1.0 1453072 ChemDiv1_005592 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3ccccc23)c4ccc(C)o4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O05 compound treatment 317.6 130.0 0.68 317.4 131.0 0.68 0.9603 1.0 1505219 ChemDiv1_005593 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O06 compound treatment 284.2 96.2 0.5 282.6 96.4 0.5 0.7092 1.0 1713098 ChemDiv1_005594 CCC1CCc2c(C(=O)OC)c(NC(=O)c3sc4ccccc4c3Cl)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O07 compound treatment 281.4 93.4 0.49 281.2 95.0 0.49 0.6938 1.0 1130872 ChemDiv1_005595 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3OC)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O08 compound treatment 290.6 103.0 0.54 286.6 100.0 0.52 0.7475 0.9999 1329993 ChemDiv1_005596 O=C1CC(Sc2nc3CCCc3cc2C#N)C(=O)N1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O09 compound treatment 285.0 97.0 0.51 281.4 95.2 0.5 0.7078 0.9999 1277410 ChemDiv1_005597 CCOc1cccc(c1)c2cc(C(=O)Nc3ccc4OCCOc4c3)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O10 compound treatment 278.9 90.9 0.47 282.1 95.9 0.5 0.6878 0.9997 1354984 ChemDiv1_005598 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc(C)ccc3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O11 compound treatment 275.5 87.5 0.46 282.6 96.4 0.5 0.6771 0.9989 1972935 ChemDiv1_005599 [O-][N+](=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O12 compound treatment 278.9 90.9 0.47 281.4 95.2 0.5 0.6853 0.9998 1972936 ChemDiv1_005600 Cc1cccc(OCCOc2ccc(Cl)cc2C=C3C(=O)NC(=S)NC3=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O13 compound treatment 280.0 92.0 0.48 275.5 89.3 0.46 0.6676 0.9999 1660121 ChemDiv1_005601 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccc3C(=O)N)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O14 compound treatment 274.3 86.3 0.45 277.5 91.3 0.47 0.654 0.9996 1508109 ChemDiv1_005602 Cn1c(SCc2ccccc2)nc3-c4ccccc4CC5(CCCC5)c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O15 compound treatment 279.6 91.6 0.48 283.0 96.8 0.5 0.6937 0.9997 1229854 ChemDiv1_005603 COC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)N)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O16 compound treatment 281.5 93.5 0.49 279.1 92.9 0.48 0.6864 1.0 1217503 ChemDiv1_005604 CCOC(=O)c1ccc(Oc2nc(NC)nc(SC)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O17 compound treatment 280.2 92.2 0.48 277.7 91.5 0.48 0.6765 1.0 1578995 ChemDiv1_005605 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O18 compound treatment 275.9 87.9 0.46 276.4 90.2 0.47 0.6558 0.9999 1972937 ChemDiv1_005606 ClC1=CCC2C(C1)C(=O)N(CC(=O)Nc3sc4CCCCc4c3C#N)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O19 compound treatment 275.9 87.9 0.46 276.4 90.2 0.47 0.6558 0.9999 1184668 ChemDiv1_005607 COc1cccc(c1)c2cc(C(=O)Nc3ccccc3OC)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O20 compound treatment 279.6 91.6 0.48 282.0 95.8 0.5 0.6901 0.9998 1972938 ChemDiv1_005608 COc1ccc(NC(=O)c2ccc(cc2)N3C(=O)C4CC=C(Cl)CC4C3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O21 compound treatment 281.9 93.9 0.49 280.7 94.5 0.49 0.6938 1.0 1694754 ChemDiv1_005609 NC(=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O22 compound treatment 276.2 88.2 0.46 273.0 86.8 0.45 0.6444 1.0 1387249 ChemDiv1_005610 COc1cc(C)nc(n1)N(CC(=O)N)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O23 mock treatment 281.0 93.0 0.49 279.1 92.9 0.48 0.6846 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 O24 mock treatment 97.5 -90.5 -0.47 92.5 -93.7 -0.49 -0.6782 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P01 compound treatment 283.2 95.2 0.5 287.3 101.0 0.53 0.7228 0.9996 1972939 ChemDiv1_005611 COc1ccc(cc1)n2c(SCC=C)nc3sc4COC(C)(C)Cc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P02 compound treatment 288.3 100.0 0.52 290.7 105.0 0.54 0.7541 0.9998 1298888 ChemDiv1_005612 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccccc5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P03 compound treatment 279.1 91.1 0.48 285.3 99.1 0.52 0.7003 0.9992 1629242 ChemDiv1_005613 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3nc(cs3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P04 compound treatment 282.9 94.9 0.49 284.3 98.1 0.51 0.7107 0.9999 1972940 ChemDiv1_005614 CCCCCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P05 compound treatment 280.5 92.5 0.48 282.5 96.3 0.5 0.6952 0.9998 1972941 ChemDiv1_005615 [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc2ccc(cc2)c3cn4ccccc4n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P06 compound treatment 279.8 91.8 0.48 281.2 95.0 0.49 0.6879 0.9999 1229490 ChemDiv1_005616 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccccc5)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P07 compound treatment 268.3 80.3 0.42 280.9 94.7 0.49 0.6443 0.9967 1465144 ChemDiv1_005617 Cc1ccn2c(NC(=O)c3cccs3)c(nc2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P08 compound treatment 284.6 96.6 0.5 283.2 97.0 0.5 0.7129 1.0 1972942 ChemDiv1_005618 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4c(F)cccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P09 compound treatment 279.6 91.6 0.48 279.1 92.9 0.48 0.6794 1.0 1589132 ChemDiv1_005619 COc1ccc2nc(Nc3nc(O)c4ccccc4n3)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P10 compound treatment 277.1 89.1 0.46 281.2 95.0 0.49 0.6779 0.9995 1972943 ChemDiv1_005620 COc1ccc(C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P11 compound treatment 283.1 95.1 0.5 282.2 96.0 0.5 0.7037 1.0 1779873 ChemDiv1_005621 CCC(=O)N1C(C)CC(N(C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-])c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P12 compound treatment 282.7 94.7 0.49 277.3 91.1 0.47 0.6842 0.9998 1972944 ChemDiv1_005622 COc1cccc(C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P13 compound treatment 277.2 89.2 0.47 281.0 94.8 0.49 0.6775 0.9996 1972945 ChemDiv1_005623 CCCCCCCC(=O)N1C(C)CC(N(C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P14 compound treatment 278.1 90.1 0.47 280.3 94.1 0.49 0.6783 0.9998 1972946 ChemDiv1_005624 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5c(F)cccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P15 compound treatment 276.9 88.9 0.46 282.0 95.8 0.5 0.6801 0.9994 1641146 ChemDiv1_005625 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P16 compound treatment 279.8 91.8 0.48 281.6 95.4 0.5 0.6893 0.9998 1972947 ChemDiv1_005626 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P17 compound treatment 279.6 91.6 0.48 281.8 95.6 0.5 0.6893 0.9998 1539177 ChemDiv1_005627 CC1CC(N(C(=O)C2CC2)c3ccccc3)c4ccccc4N1C(=O)C5CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P18 compound treatment 281.7 93.7 0.49 277.8 91.6 0.48 0.6824 0.9999 1927909 ChemDiv1_005628 Cn1cnnc1SCC(=O)N2CCCc3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P19 compound treatment 277.4 89.4 0.47 279.2 93.0 0.48 0.6717 0.9998 1618765 ChemDiv1_005629 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccc(NS(=O)(=O)C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P20 compound treatment 277.3 89.3 0.47 281.6 95.4 0.5 0.6801 0.9995 1972948 ChemDiv1_005630 Fc1ccccc1c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P21 compound treatment 277.5 89.5 0.47 277.8 91.6 0.48 0.6669 0.9999 1240360 ChemDiv1_005631 COc1ccc(OCC(=O)N(C2CC(C)N(C(=O)COc3ccc(OC)cc3)c4ccccc24)c5ccccc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P22 compound treatment 277.4 89.4 0.47 278.9 92.7 0.48 0.6706 0.9999 1972949 ChemDiv1_005632 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P23 mock treatment 281.8 93.8 0.49 277.8 91.6 0.48 0.6827 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.602 P24 mock treatment 99.6 -88.4 -0.46 97.3 -88.9 -0.46 -0.6528 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A01 compound treatment 286.2 97.9 0.51 286.4 99.6 0.52 0.7275 1.0 1972950 ChemDiv1_005633 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(OC)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A02 compound treatment 278.4 90.1 0.47 278.9 92.1 0.48 0.6712 1.0 1605626 ChemDiv1_005634 Oc1ccc(Nc2nc3nonc3nc2Nc4ccc(O)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A03 compound treatment 282.3 94.0 0.49 285.6 98.8 0.51 0.7102 0.9997 1972951 ChemDiv1_005635 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A04 compound treatment 281.6 93.3 0.49 280.8 94.0 0.49 0.69 1.0 1369228 ChemDiv1_005636 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A05 compound treatment 283.4 95.1 0.5 282.6 95.8 0.5 0.7032 1.0 1189514 ChemDiv1_005637 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc3OCOc3c2)C(=O)Nc4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A06 compound treatment 280.7 92.4 0.48 281.0 94.2 0.49 0.6874 1.0 1403900 ChemDiv1_005638 O=C(CSc1nc2ccc(NC(=O)c3ccccc3C(=O)N4CCCC4)cc2s1)NC5CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A07 compound treatment 279.0 90.7 0.47 287.2 100.0 0.52 0.7039 0.9988 1348397 ChemDiv1_005639 COc1ccc(OC)c(c1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A08 compound treatment 282.0 93.7 0.49 280.8 94.0 0.49 0.6915 1.0 1918192 ChemDiv1_005640 CCOC(=O)C1=C(N)Oc2c(C1c3cccc(c3)[N+](=O)[O-])c(=O)oc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A09 compound treatment 276.0 87.7 0.46 280.5 93.7 0.49 0.6682 0.9995 1950303 ChemDiv1_005641 COc1ccc(OC)c(c1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A10 compound treatment 277.7 89.4 0.47 277.9 91.1 0.47 0.6649 1.0 1972952 ChemDiv1_005642 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)c(OC)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A11 compound treatment 275.8 87.5 0.46 280.2 93.4 0.49 0.6664 0.9995 1145505 ChemDiv1_005643 Clc1ccc(Oc2ccccc2)c(NC(=O)CSc3nc4ccccc4o3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A12 compound treatment 275.6 87.3 0.46 280.8 94.0 0.49 0.6678 0.9994 1972953 ChemDiv1_005644 CC(C)(C)c1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A13 compound treatment 280.5 92.2 0.48 282.3 95.5 0.5 0.6914 0.9999 1972954 ChemDiv1_005645 COc1cc(cc2sc(NC(=O)C3(CC4CC5CC(C4)C3)C5)nc12)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A14 compound treatment 279.6 91.3 0.48 279.7 92.9 0.48 0.6786 1.0 1972955 ChemDiv1_005646 CCC1C(=O)N=C(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)N(C1=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A15 compound treatment 279.2 90.9 0.47 276.6 89.8 0.47 0.6657 1.0 1972956 ChemDiv1_005647 Cc1cc(c(C#N)c(SC2CC(=O)N(C2=O)c3ccccc3)n1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A16 compound treatment 281.7 93.4 0.49 287.6 101.0 0.52 0.7153 0.9993 1947229 ChemDiv1_005648 Nc1nc(SCC(=O)c2ccc(O)c(O)c2)c(C#N)c(c1C#N)c3ccc(O)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A17 compound treatment 277.9 89.6 0.47 280.3 93.5 0.49 0.6745 0.9998 1972957 ChemDiv1_005649 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc(OC)ccc3OC)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A18 compound treatment 279.5 91.2 0.48 278.4 91.6 0.48 0.6734 1.0 1609447 ChemDiv1_005650 COC(=O)C1C(C(=C(NC1=O)SCc2cccc3ccccc23)C#N)c4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A19 compound treatment 327.7 139.0 0.73 325.8 139.0 0.72 1.0254 1.0 1972958 ChemDiv1_005651 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cc(OC)ccc3OC)c(O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A20 compound treatment 274.7 86.4 0.45 274.7 87.9 0.46 0.6421 1.0 1338015 ChemDiv1_005652 CCOC(=O)c1c(C)c(sc1NC(=O)COc2c(F)c(F)cc(F)c2F)C(=O)N(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A21 compound treatment 277.4 89.1 0.47 275.9 89.1 0.46 0.6565 1.0 1972959 ChemDiv1_005653 COc1cccc(c1)c2nnc(SCC(=O)c3cccs3)n2CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A22 compound treatment 286.5 98.2 0.51 292.1 105.0 0.55 0.7496 0.9995 1972960 ChemDiv1_005654 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A23 mock treatment 281.7 93.4 0.49 276.5 89.7 0.47 0.6745 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 A24 mock treatment 78.9 -109.0 -0.57 78.0 -109.0 -0.57 -0.8031 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B01 compound treatment 285.0 96.7 0.5 286.1 99.3 0.52 0.722 0.9999 1226634 ChemDiv1_005655 CCOC(=O)c1c(C)c(sc1NC(=O)C(C)Oc2c(F)c(F)cc(F)c2F)C(=O)N(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B02 compound treatment 281.1 92.8 0.48 282.7 95.9 0.5 0.6951 0.9999 1630339 ChemDiv1_005656 OCCNc1nc(Cl)nc(n1)N2CCC(Cc3ccccc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B03 compound treatment 283.3 95.0 0.5 282.0 95.2 0.5 0.7007 1.0 1972961 ChemDiv1_005657 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4c(F)cccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B04 compound treatment 282.1 93.8 0.49 280.6 93.8 0.49 0.6911 1.0 1589231 ChemDiv1_005658 Clc1ccccc1N2CC(CC2=O)C(=O)Nc3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B05 compound treatment 281.2 92.9 0.48 283.9 97.1 0.5 0.6999 0.9998 1174511 ChemDiv1_005659 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B06 compound treatment 277.5 89.2 0.47 284.4 97.6 0.51 0.6881 0.9991 1972962 ChemDiv1_005660 OC(=O)c1ccccc1NC(=O)CN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B07 compound treatment 277.0 88.7 0.46 277.6 90.8 0.47 0.6612 1.0 1972963 ChemDiv1_005661 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B08 compound treatment 278.0 89.7 0.47 278.7 91.9 0.48 0.669 0.9999 1972964 ChemDiv1_005662 CN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B09 compound treatment 280.7 92.4 0.48 289.5 103.0 0.53 0.7186 0.9987 1972965 ChemDiv1_005663 COc1ccc(cc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B10 compound treatment 274.0 85.7 0.45 280.0 93.2 0.48 0.659 0.9992 1476095 ChemDiv1_005664 COC(=O)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B11 compound treatment 278.0 89.7 0.47 277.3 90.5 0.47 0.6638 1.0 1972966 ChemDiv1_005665 CC(NC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B12 compound treatment 281.1 92.8 0.48 278.7 91.9 0.48 0.6804 1.0 1972967 ChemDiv1_005666 CCOc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B13 compound treatment 274.4 86.1 0.45 276.8 90.0 0.47 0.6487 0.9998 1972968 ChemDiv1_005667 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4C(=O)O)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B14 compound treatment 282.5 94.2 0.49 277.9 91.1 0.47 0.6826 0.9998 1925921 ChemDiv1_005668 Cc1[n+]([O-])c2ccccc2n(OCC=C)c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B15 compound treatment 282.0 93.7 0.49 271.2 84.4 0.44 0.6562 0.9985 1341470 ChemDiv1_005669 Fc1cccc(Nc2nc3nonc3nc2Nc4cccc(F)c4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B16 compound treatment 280.3 92.0 0.48 278.9 92.1 0.48 0.6782 1.0 1338300 ChemDiv1_005670 Fc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B17 compound treatment 278.4 90.1 0.47 277.5 90.7 0.47 0.666 1.0 1972969 ChemDiv1_005671 CCC(C)Nc1nc(OCC(F)(F)F)nc(OCC(F)(F)F)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B18 compound treatment 274.7 86.4 0.45 278.7 91.9 0.48 0.6568 0.9996 1671762 ChemDiv1_005672 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5ccccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B19 compound treatment 274.2 85.9 0.45 277.6 90.8 0.47 0.6509 0.9997 1684053 ChemDiv1_005673 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3cccc(OC(=O)c4ccco4)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B20 compound treatment 277.8 89.5 0.47 278.2 91.4 0.48 0.6664 1.0 1478373 ChemDiv1_005674 COc1cccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B21 compound treatment 274.2 85.9 0.45 276.6 89.8 0.47 0.6472 0.9998 1972970 ChemDiv1_005675 CCS(=O)(=O)c1ccc2nc(SCc3ccccc3Cl)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B22 compound treatment 276.3 88.0 0.46 277.5 90.7 0.47 0.6583 0.9999 1972971 ChemDiv1_005676 CC(C)N1C(=O)/C(=C\c2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])/c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B23 mock treatment 279.6 91.3 0.48 280.2 93.4 0.49 0.6804 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 B24 mock treatment 77.6 -111.0 -0.58 74.7 -112.0 -0.58 -0.82 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C01 compound treatment 285.4 97.1 0.51 287.2 100.0 0.52 0.7275 0.9999 1972972 ChemDiv1_005677 Cc1nn(CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4)c(C)c1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C02 compound treatment 283.9 95.6 0.5 284.7 97.9 0.51 0.7128 0.9999 1559918 ChemDiv1_005678 CCCCN(CN1C(=O)C2C3CC(C=C3)C2C1=O)CN4C(=O)C5C6CC(C=C6)C5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C03 compound treatment 278.6 90.3 0.47 281.1 94.3 0.49 0.68 0.9998 1334069 ChemDiv1_005679 CC(C)(C)c1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C04 compound treatment 288.0 99.7 0.52 286.7 99.9 0.52 0.7353 1.0 1972973 ChemDiv1_005680 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(o3)c4ccccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C05 compound treatment 279.9 91.6 0.48 281.3 94.5 0.49 0.6855 0.9999 1950530 ChemDiv1_005681 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccc(OC)cc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C06 compound treatment 281.8 93.5 0.49 282.3 95.5 0.5 0.6962 1.0 1170129 ChemDiv1_005682 O=C(CSc1nc2ccc(NC(=O)c3ccccc3C(=O)N4CCCC4)cc2s1)NC5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C07 compound treatment 284.0 95.7 0.5 277.9 91.1 0.47 0.6882 0.9997 1318531 ChemDiv1_005683 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C08 compound treatment 282.1 93.8 0.49 282.5 95.7 0.5 0.6981 1.0 1972974 ChemDiv1_005684 COc1cc(cc(Br)c1OC)C2C(=C(N)OC3=C2C(=O)CCC3)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C09 compound treatment 275.5 87.2 0.46 276.7 89.9 0.47 0.6524 0.9999 1972975 ChemDiv1_005685 CCOc1ccccc1N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C10 compound treatment 279.0 90.7 0.47 276.9 90.1 0.47 0.6661 1.0 1721036 ChemDiv1_005686 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CCC4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C11 compound treatment 281.9 93.6 0.49 278.4 91.6 0.48 0.6823 0.9999 1972976 ChemDiv1_005687 CCCC/1=NN(C(=O)\C1=C(\C)/Nc2cc(Cl)ccc2O)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C12 compound treatment 277.5 89.2 0.47 276.7 89.9 0.47 0.6598 1.0 1685915 ChemDiv1_005688 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)C(C)(C)C)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C13 compound treatment 321.2 133.0 0.69 329.4 143.0 0.74 1.0147 0.9994 1972977 ChemDiv1_005689 CN(C)c1ccc(/C=C/2\Sc3c(ccc4ccccc34)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C14 compound treatment 284.8 96.5 0.5 287.3 101.0 0.52 0.7257 0.9998 1972978 ChemDiv1_005690 CCC1C(=O)N=C(SCC(=O)Nc2ccc(C)cc2)N(C1=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C15 compound treatment 273.3 85.0 0.44 272.5 85.7 0.45 0.6289 1.0 1946889 ChemDiv1_005691 COc1ccc2[nH]c(SCC(=O)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C16 compound treatment 348.7 160.0 0.84 358.7 172.0 0.89 1.2238 0.9995 1704015 ChemDiv1_005692 Oc1ccc(cc1O)C(=O)CSc2nc(ccc2C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C17 compound treatment 276.3 88.0 0.46 280.6 93.8 0.49 0.6697 0.9995 1972979 ChemDiv1_005693 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(C)c3)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C18 compound treatment 276.3 88.0 0.46 272.8 86.0 0.45 0.641 0.9999 1511119 ChemDiv1_005694 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccc(Cl)cc2)C(=O)OC(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C19 compound treatment 279.1 90.8 0.47 280.2 93.4 0.49 0.6786 0.9999 1972980 ChemDiv1_005695 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(cc3)C4C(=C(N)Oc5[nH]nc(CCC)c45)C#N)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C20 compound treatment 278.2 89.9 0.47 279.4 92.6 0.48 0.6723 0.9999 1972981 ChemDiv1_005696 COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C21 compound treatment 278.4 90.1 0.47 277.1 90.3 0.47 0.6646 1.0 1741305 ChemDiv1_005697 Cc1c(Nc2nc3nonc3nc2Nc4ccc(C)cc4C)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C22 compound treatment 278.5 90.2 0.47 277.5 90.7 0.47 0.6664 1.0 1972982 ChemDiv1_005698 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C23 mock treatment 279.1 90.8 0.47 280.3 93.5 0.49 0.6789 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 C24 mock treatment 81.8 -106.0 -0.56 76.0 -111.0 -0.58 -0.7998 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D01 compound treatment 295.2 107.0 0.56 292.4 106.0 0.55 0.7828 1.0 1706606 ChemDiv1_005699 NC(=O)c1c(NC(=O)CSc2nc3ccccc3o2)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D02 compound treatment 282.9 94.6 0.49 278.9 92.1 0.48 0.6878 0.9999 1364384 ChemDiv1_005700 Cc1cccc(Nc2nc(NCc3ccco3)nc(n2)N4CCOCC4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D03 compound treatment 281.1 92.8 0.48 281.8 95.0 0.49 0.6918 1.0 1637238 ChemDiv1_005701 Clc1cc(nc(n1)N2CCOCC2)N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D04 compound treatment 278.8 90.5 0.47 285.2 98.4 0.51 0.6958 0.9992 1972983 ChemDiv1_005702 Clc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc(Br)cc3)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D05 compound treatment 281.4 93.1 0.49 281.3 94.5 0.49 0.6911 1.0 1231438 ChemDiv1_005703 CCOc1ccc(NC(=O)c2sc3nc(N)c(C#N)c(c4ccc(OC)c(OC)c4)c3c2N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D06 compound treatment 282.9 94.6 0.49 282.9 96.1 0.5 0.7025 1.0 1972984 ChemDiv1_005704 [O-][N+](=O)c1ccccc1NC(=O)CN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D07 compound treatment 279.4 91.1 0.48 279.5 92.7 0.48 0.6771 1.0 1972985 ChemDiv1_005705 CC1SC2(N(C1=O)c3ccc(Br)cc3)C(=O)Nc4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D08 compound treatment 275.9 87.6 0.46 280.7 93.9 0.49 0.6686 0.9995 1972986 ChemDiv1_005706 FC(F)(F)c1oc2cc(OC(=O)c3ccco3)ccc2c(=O)c1Oc4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D09 compound treatment 280.6 92.3 0.48 279.0 92.2 0.48 0.6797 1.0 1972987 ChemDiv1_005707 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D10 compound treatment 282.2 93.9 0.49 280.9 94.1 0.49 0.6926 1.0 1171304 ChemDiv1_005708 CCOC(=O)c1ccc(Nc2ncnc3ccc(Br)cc23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D11 compound treatment 276.3 88.0 0.46 277.6 90.8 0.47 0.6587 0.9999 1397851 ChemDiv1_005709 CSc1nc2ccccc2n1CC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D12 compound treatment 281.8 93.5 0.49 276.0 89.2 0.46 0.6731 0.9997 1924036 ChemDiv1_005710 CCc1ccc(/C=C/2\N(C(=O)C)C(=O)NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D13 compound treatment 276.8 88.5 0.46 279.2 92.4 0.48 0.6664 0.9998 1666837 ChemDiv1_005711 Cc1ccc(cc1)C(=O)c2oc3ccccc3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D14 compound treatment 280.0 91.7 0.48 278.6 91.8 0.48 0.676 1.0 1784510 ChemDiv1_005712 CCOC(=O)COn1c(=O)c(C)[n+]([O-])c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D15 compound treatment 273.9 85.6 0.45 280.2 93.4 0.49 0.6594 0.9991 1397390 ChemDiv1_005713 Cc1ccc(Nc2nc3nonc3nc2N4CCCCC4)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D16 compound treatment 277.9 89.6 0.47 278.9 92.1 0.48 0.6693 0.9999 1589310 ChemDiv1_005714 CN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D17 compound treatment 276.3 88.0 0.46 277.6 90.8 0.47 0.6587 0.9999 1972988 ChemDiv1_005715 CC(C)(C)Nc1nc(OCC(F)(F)F)nc(OCC(F)(F)F)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D18 compound treatment 274.5 86.2 0.45 278.8 92.0 0.48 0.6564 0.9995 1386024 ChemDiv1_005716 COc1ccccc1n2c(SC)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D19 compound treatment 265.7 77.4 0.4 280.1 93.3 0.49 0.6288 0.9959 1282415 ChemDiv1_005717 NC1=C(C#N)C2(C(=O)N(C(=O)c3ccccc3Cl)c4ccccc42)C5=C(CCCC5=O)O1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D20 compound treatment 279.2 90.9 0.47 278.9 92.1 0.48 0.6741 1.0 1572075 ChemDiv1_005718 CCOC(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D21 compound treatment 276.9 88.6 0.46 277.8 91.0 0.47 0.6616 0.9999 1972989 ChemDiv1_005719 CCOc1c(OC)cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D22 compound treatment 277.7 89.4 0.47 278.5 91.7 0.48 0.6671 0.9999 1972990 ChemDiv1_005720 CCN1C(=O)/C(=C/c2nc3ccccc3c(=O)n2c4ccccc4[N+](=O)[O-])/c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D23 mock treatment 277.4 89.1 0.47 278.2 91.4 0.48 0.6649 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 D24 mock treatment 77.4 -111.0 -0.58 82.2 -105.0 -0.54 -0.7932 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E01 compound treatment 282.1 93.8 0.49 287.5 101.0 0.52 0.7165 0.9994 1331756 ChemDiv1_005721 Fc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E02 compound treatment 280.9 92.6 0.48 288.1 101.0 0.53 0.7142 0.9991 1972991 ChemDiv1_005722 CCCCSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E03 compound treatment 282.8 94.5 0.49 285.4 98.6 0.51 0.7113 0.9998 1972992 ChemDiv1_005723 CCCCOc1ccc(cc1)C(=O)On2c(C)nc3ccccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E04 compound treatment 280.8 92.5 0.48 282.5 95.7 0.5 0.6933 0.9999 1159523 ChemDiv1_005724 CCn1c(NC(=O)c2cccs2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E05 compound treatment 278.4 90.1 0.47 285.2 98.4 0.51 0.6943 0.9991 1381269 ChemDiv1_005725 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(F)c2)C(=O)Nc3ccc(OC)cc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E06 compound treatment 282.3 94.0 0.49 279.7 92.9 0.48 0.6885 1.0 1972993 ChemDiv1_005726 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc4nc(SCC(=O)NCC5CCCO5)sc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E07 compound treatment 282.1 93.8 0.49 279.7 92.9 0.48 0.6878 1.0 1304345 ChemDiv1_005727 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccc(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E08 compound treatment 281.2 92.9 0.48 284.5 97.7 0.51 0.7021 0.9997 1972994 ChemDiv1_005728 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E09 compound treatment 277.8 89.5 0.47 282.4 95.6 0.5 0.6818 0.9995 1972995 ChemDiv1_005729 CCC(=O)OC1=C(C)C2C3C(C(=O)N(C3=O)c4ccc(F)cc4)C1(C)C5C2C(=O)N(C5=O)c6ccc(F)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E10 compound treatment 278.1 89.8 0.47 280.2 93.4 0.49 0.6749 0.9998 1151783 ChemDiv1_005730 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccccc3OC(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E11 compound treatment 283.9 95.6 0.5 279.8 93.0 0.48 0.6948 0.9999 1972996 ChemDiv1_005731 CCCC/1=NN(C(=O)\C1=C(/C)\Nc2cccc(F)c2)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E12 compound treatment 283.4 95.1 0.5 278.9 92.1 0.48 0.6896 0.9998 1972997 ChemDiv1_005732 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)N(C(=O)c4ccccc4)c5ccccc53)c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E13 compound treatment 280.8 92.5 0.48 284.4 97.6 0.51 0.7003 0.9997 1972998 ChemDiv1_005733 [O-][N+](=O)c1csc(NC(=O)c2cc3ccccc3o2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E14 compound treatment 281.9 93.6 0.49 282.6 95.8 0.5 0.6977 1.0 1972999 ChemDiv1_005734 CC(C)Cc1c(C#N)c(N)nc(SCC(=O)c2cc3cc(Br)ccc3oc2=O)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E15 compound treatment 280.4 92.1 0.48 281.2 94.4 0.49 0.687 0.9999 1690001 ChemDiv1_005735 Cc1ccc2cccc(SCc3nc(N)nc(Nc4ccccc4)n3)c2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E16 compound treatment 280.1 91.8 0.48 277.7 90.9 0.47 0.6731 1.0 1973000 ChemDiv1_005736 O=C1NC(=C(C#N)C2(CCCCC2)C1C#N)SCCCCSC3=C(C#N)C4(CCCCC4)C(C#N)C(=O)N3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E17 compound treatment 279.6 91.3 0.48 281.4 94.6 0.49 0.6848 0.9999 1973001 ChemDiv1_005737 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3ccc(OC)cc3OC)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E18 compound treatment 278.6 90.3 0.47 279.5 92.7 0.48 0.6741 0.9999 1544101 ChemDiv1_005738 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E19 compound treatment 272.2 83.9 0.44 279.6 92.8 0.48 0.6509 0.9988 1973002 ChemDiv1_005739 CCCCNc1nc(Nc2ccc(Cl)cc2)nc(n1)N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E20 compound treatment 277.1 88.8 0.46 278.7 91.9 0.48 0.6657 0.9999 1973003 ChemDiv1_005740 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OC)c(OC)c3OC)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E21 compound treatment 273.5 85.2 0.44 272.3 85.5 0.44 0.6289 1.0 1274934 ChemDiv1_005741 Cc1nccn1c2nc3nonc3nc2Nc4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E22 compound treatment 280.8 92.5 0.48 275.0 88.2 0.46 0.6657 0.9997 1973004 ChemDiv1_005742 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E23 mock treatment 283.4 95.1 0.5 279.3 92.5 0.48 0.6911 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 E24 mock treatment 85.1 -103.0 -0.54 80.2 -107.0 -0.55 -0.7722 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F01 compound treatment 287.7 99.4 0.52 288.2 101.0 0.53 0.7397 1.0 1487742 ChemDiv1_005743 NC(=O)c1c(NC(=O)CSc2nc3ccccc3o2)sc4CCCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F02 compound treatment 283.5 95.2 0.5 280.1 93.3 0.49 0.6944 0.9999 1154675 ChemDiv1_005744 CCc1nnc(SCC(=O)Nc2nncs2)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F03 compound treatment 280.6 92.3 0.48 283.9 97.1 0.5 0.6977 0.9997 1392623 ChemDiv1_005745 CCCC(=O)Oc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F04 compound treatment 281.8 93.5 0.49 282.0 95.2 0.5 0.6951 1.0 1524851 ChemDiv1_005746 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OC(=O)c4ccccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F05 compound treatment 280.9 92.6 0.48 282.4 95.6 0.5 0.6933 0.9999 1689008 ChemDiv1_005747 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F06 compound treatment 283.1 94.8 0.49 290.7 104.0 0.54 0.7319 0.999 1923569 ChemDiv1_005748 OCCN(C(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F07 compound treatment 280.6 92.3 0.48 282.5 95.7 0.5 0.6925 0.9999 1973005 ChemDiv1_005749 CN1C(=O)N(C)C(=O)C(=Cc2ccc(N3CCN(CC3)C(=O)c4ccccc4)c(c2)[N+](=O)[O-])C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F08 compound treatment 289.3 101.0 0.53 291.9 105.0 0.55 0.7592 0.9998 1973006 ChemDiv1_005750 CCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F09 compound treatment 282.7 94.4 0.49 284.1 97.3 0.51 0.7062 0.9999 1973007 ChemDiv1_005751 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc(cc4)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F10 compound treatment 278.9 90.6 0.47 282.6 95.8 0.5 0.6866 0.9997 1312514 ChemDiv1_005752 Brc1ccc2ncnc(NCCN3CCOCC3)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F11 compound treatment 281.4 93.1 0.49 285.0 98.2 0.51 0.7047 0.9997 1261546 ChemDiv1_005753 Cn1c(Sc2ncnn2CC(=O)NC(C)(C)C)nc3n(C)c(=O)n(C)c(=O)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F12 compound treatment 291.9 104.0 0.54 290.5 104.0 0.54 0.7636 1.0 1784110 ChemDiv1_005754 NS(=O)(=O)c1ccc(cc1)N2N=C(CC2c3ccccc3)/C=C/c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F13 compound treatment 278.1 89.8 0.47 280.8 94.0 0.49 0.6771 0.9998 1973008 ChemDiv1_005755 CCN(CC)CCCC(C)N/C(=C/1\C(=O)NC(=O)N(C1=O)c2ccc(OC)cc2)/CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F14 compound treatment 359.1 171.0 0.89 367.7 181.0 0.94 1.2953 0.9996 1784511 ChemDiv1_005756 [O-][n+]1cc(=O)n(OCc2ccccc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F15 compound treatment 284.3 96.0 0.5 284.7 97.9 0.51 0.7143 1.0 1118666 ChemDiv1_005757 CC1CC(C)CN(C1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F16 compound treatment 279.6 91.3 0.48 278.4 91.6 0.48 0.6738 1.0 1483149 ChemDiv1_005758 COC(=O)CCNc1nc(nc2ccccc12)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F17 compound treatment 277.7 89.4 0.47 281.4 94.6 0.49 0.6778 0.9996 1973009 ChemDiv1_005759 CC(C)OC(=O)CSc1nc2CCCc2c(C3CCC=CC3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F18 compound treatment 274.8 86.5 0.45 277.4 90.6 0.47 0.6524 0.9998 1973010 ChemDiv1_005760 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F19 compound treatment 279.3 91.0 0.47 275.9 89.1 0.46 0.6635 0.9999 1973011 ChemDiv1_005761 COc1cc(cc(OC)c1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cccc(c5)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F20 compound treatment 277.9 89.6 0.47 271.0 84.2 0.44 0.6403 0.9995 1367796 ChemDiv1_005762 CCCOC(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F21 compound treatment 246.3 58.0 0.3 239.7 52.9 0.28 0.4087 0.9989 1523650 ChemDiv1_005763 Nc1nc2nonc2nc1N3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F22 compound treatment 277.0 88.7 0.46 279.0 92.2 0.48 0.6664 0.9998 1935860 ChemDiv1_005764 CCCN1C(=O)/C(=C/c2nc3ccccc3c(=O)n2c4ccccc4[N+](=O)[O-])/c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F23 mock treatment 281.1 92.8 0.48 274.5 87.7 0.46 0.665 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 F24 mock treatment 78.7 -110.0 -0.57 76.5 -110.0 -0.57 -0.8094 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G01 compound treatment 281.7 93.4 0.49 285.9 99.1 0.52 0.7091 0.9996 1973012 ChemDiv1_005765 Cc1cc(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccccc4F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G02 compound treatment 277.3 89.0 0.46 282.8 96.0 0.5 0.6815 0.9994 1973013 ChemDiv1_005766 COc1cccc(c1)n2c(/C=C/3\C(=O)N(C(C)C)c4ccccc34)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G03 compound treatment 282.7 94.4 0.49 286.0 99.2 0.52 0.7132 0.9997 1612220 ChemDiv1_005767 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G04 compound treatment 286.5 98.2 0.51 290.8 104.0 0.54 0.7448 0.9996 1973014 ChemDiv1_005768 CC(=O)Nc1nc2cc(C)c(C)cc2[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G05 compound treatment 285.1 96.8 0.51 284.3 97.5 0.51 0.7158 1.0 1973015 ChemDiv1_005769 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G06 compound treatment 278.9 90.6 0.47 282.7 95.9 0.5 0.687 0.9996 1973016 ChemDiv1_005770 COC(=O)c1ccccc1NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccc(cc5C4=O)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G07 compound treatment 279.3 91.0 0.47 283.6 96.8 0.5 0.6918 0.9996 1950457 ChemDiv1_005771 CCOc1cc(cc([N+](=O)[O-])c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G08 compound treatment 278.0 89.7 0.47 278.2 91.4 0.48 0.6671 1.0 1131464 ChemDiv1_005772 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccccc3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G09 compound treatment 281.7 93.4 0.49 280.7 93.9 0.49 0.69 1.0 1973017 ChemDiv1_005773 CCC(=O)OC1=C(C)C2C3C(C(=O)N(C3=O)c4ccccc4F)C1(C)C5C2C(=O)N(C5=O)c6ccccc6F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G10 compound treatment 277.9 89.6 0.47 281.8 95.0 0.49 0.68 0.9996 1155684 ChemDiv1_005774 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OC(=O)N4CCOCC4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G11 compound treatment 275.6 87.3 0.46 279.7 92.9 0.48 0.6638 0.9996 1973018 ChemDiv1_005775 CCCN/C(=C\1/C(=O)N(N=C1CCC)c2nc3ccccc3s2)/C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G12 compound treatment 279.9 91.6 0.48 278.2 91.4 0.48 0.6742 1.0 1289583 ChemDiv1_005776 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(OC(=O)c4ccccc4Cl)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G13 compound treatment 273.2 84.9 0.44 264.2 77.4 0.4 0.598 0.9989 1973019 ChemDiv1_005777 O=C1/C(=C/2\Sc3ccccc3C2=O)/Nc4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G14 compound treatment 272.4 84.1 0.44 275.1 88.3 0.46 0.6351 0.9997 1973020 ChemDiv1_005778 CCOC(=O)C1=C(N)OC2=C(C1C3CCCCC3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G15 compound treatment 274.4 86.1 0.45 275.7 88.9 0.46 0.6447 0.9999 1973021 ChemDiv1_005779 O=C(NCCc1ccc(cc1)S(=O)(=O)N2CCCCC2)c3ccc4C(=O)c5ccccc5C(=O)c4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G16 compound treatment 276.3 88.0 0.46 276.7 89.9 0.47 0.6554 1.0 1256563 ChemDiv1_005780 CC(=Cc1ccc(C#N)c(SCC(=O)c2cc3ccccc3oc2=O)n1)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G17 compound treatment 276.5 88.2 0.46 281.0 94.2 0.49 0.6719 0.9995 1973022 ChemDiv1_005781 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G18 compound treatment 278.6 90.3 0.47 277.5 90.7 0.47 0.6668 1.0 1121954 ChemDiv1_005782 CSC1=C(C#N)C(C(=C(C)N1)C(=O)OC(C)(C)C)c2ccc(Cl)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G19 compound treatment 281.4 93.1 0.49 280.7 93.9 0.49 0.6889 1.0 1742540 ChemDiv1_005783 C1CN(CCO1)c2nc(Nc3ccccc3)nc(Nc4ccccc4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G20 compound treatment 281.5 93.2 0.49 278.9 92.1 0.48 0.6826 1.0 1973023 ChemDiv1_005784 COc1cccc(c1)N2C(=O)/C(=C/c3c(OC)ccc4ccccc34)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G21 compound treatment 278.4 90.1 0.47 278.8 92.0 0.48 0.6708 1.0 1704844 ChemDiv1_005785 C1CCN(C1)c2nc3nonc3nc2N4CCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G22 compound treatment 273.7 85.4 0.45 278.5 91.7 0.48 0.6524 0.9994 1973024 ChemDiv1_005786 CC1C(=O)N(C(c2ccc(Br)cc2)S1(=O)=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G23 mock treatment 280.4 92.1 0.48 278.2 91.4 0.48 0.676 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 G24 mock treatment 81.1 -107.0 -0.56 79.9 -107.0 -0.56 -0.788 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H01 compound treatment 285.5 97.2 0.51 283.8 97.0 0.5 0.7154 1.0 1973025 ChemDiv1_005787 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(Br)cc3)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H02 compound treatment 287.1 98.8 0.52 286.2 99.4 0.52 0.7301 1.0 1973026 ChemDiv1_005788 CCn1c(SCc2nc3ccc(cc3[nH]2)[N+](=O)[O-])nc4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H03 compound treatment 284.5 96.2 0.5 285.5 98.7 0.51 0.718 0.9999 1973027 ChemDiv1_005789 COc1ccc(cc1)C(=O)CSc2nc(N)c(C#N)c(C3CCCCC3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H04 compound treatment 281.1 92.8 0.48 285.3 98.5 0.51 0.7047 0.9996 1973028 ChemDiv1_005790 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccc(N4CCOCC4)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H05 compound treatment 284.0 95.7 0.5 281.8 95.0 0.49 0.7025 1.0 1784759 ChemDiv1_005791 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H06 compound treatment 281.6 93.3 0.49 284.5 97.7 0.51 0.7036 0.9998 1973029 ChemDiv1_005792 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H07 compound treatment 280.6 92.3 0.48 281.7 94.9 0.49 0.6896 0.9999 1973030 ChemDiv1_005793 Cc1c(NC(=O)CSc2nc[nH]n2)c(=O)n(c3ccccc3)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H08 compound treatment 278.3 90.0 0.47 279.4 92.6 0.48 0.6727 0.9999 1941426 ChemDiv1_005794 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H09 compound treatment 277.6 89.3 0.47 281.9 95.1 0.49 0.6793 0.9996 1973031 ChemDiv1_005795 COc1ccc(OC)c(c1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H10 compound treatment 281.9 93.6 0.49 279.5 92.7 0.48 0.6863 1.0 1617513 ChemDiv1_005796 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H11 compound treatment 281.9 93.6 0.49 279.1 92.3 0.48 0.6848 1.0 1205726 ChemDiv1_005797 CCN(CC)CCn1c(NC(=O)COc2c(F)c(F)cc(F)c2F)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H12 compound treatment 373.2 185.0 0.96 370.1 183.0 0.95 1.3561 1.0 1425860 ChemDiv1_005798 CN(C)c1ccc(C=c2sc3=NC(=C(C(c4ccc(C)o4)n3c2=O)C(=O)Nc5ccccc5)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H13 compound treatment 277.1 88.8 0.46 278.7 91.9 0.48 0.6657 0.9999 1973032 ChemDiv1_005799 [O-][N+](=O)c1ccc(cc1)C(C2C(=O)NC(=S)N(C2=O)c3ccccc3)C4C(=O)NC(=S)N(C4=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H14 compound treatment 340.2 152.0 0.79 349.2 162.0 0.84 1.1575 0.9995 1973033 ChemDiv1_005800 CCOn1c(=O)c[n+]([O-])c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H15 compound treatment 278.8 90.5 0.47 280.9 94.1 0.49 0.68 0.9998 1589086 ChemDiv1_005801 C1Oc2ccc(Nc3nc4nonc4nc3N5CCOCC5)cc2O1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H16 compound treatment 280.0 91.7 0.48 278.3 91.5 0.48 0.6749 1.0 1973034 ChemDiv1_005802 O=C(CN1C(=O)C2CCC(=O)CC2C1=O)N3CCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H17 compound treatment 287.7 99.4 0.52 284.8 98.0 0.51 0.7272 1.0 1973035 ChemDiv1_005803 Nc1nc(SCC(=O)Nc2ccc([N+](=O)[O-])c3ccccc23)c(C#N)c(c4ccco4)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H18 compound treatment 279.5 91.2 0.48 278.8 92.0 0.48 0.6749 1.0 1973036 ChemDiv1_005804 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H19 compound treatment 275.1 86.8 0.45 278.3 91.5 0.48 0.6568 0.9997 1973037 ChemDiv1_005805 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C4(C(=O)Nc5ccc(Br)cc54)c23)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H20 compound treatment 275.6 87.3 0.46 275.6 88.8 0.46 0.6487 1.0 1335779 ChemDiv1_005806 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H21 compound treatment 277.5 89.2 0.47 278.5 91.7 0.48 0.6664 0.9999 1180045 ChemDiv1_005807 COc1ccc(Cl)cc1Nc2nc3nonc3nc2Nc4cc(Cl)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H22 compound treatment 281.9 93.6 0.49 277.2 90.4 0.47 0.6779 0.9998 1973038 ChemDiv1_005808 COc1ccccc1n2c(/C=C/3\C(=O)N(C)c4ccc(Br)cc34)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H23 mock treatment 281.9 93.6 0.49 277.8 91.0 0.47 0.6801 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 H24 mock treatment 82.1 -106.0 -0.55 79.4 -107.0 -0.56 -0.7862 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I01 compound treatment 279.7 91.4 0.48 283.6 96.8 0.5 0.6933 0.9996 1973039 ChemDiv1_005809 COc1cc(/C=C\C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I02 compound treatment 277.4 89.1 0.47 283.8 97.0 0.5 0.6855 0.9992 1973040 ChemDiv1_005810 COc1cccc(c1)n2c(/C=C/3\C(=O)N(C)c4ccc(Br)cc34)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I03 compound treatment 282.1 93.8 0.49 284.9 98.1 0.51 0.7069 0.9998 1516615 ChemDiv1_005811 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I04 compound treatment 281.3 93.0 0.49 282.6 95.8 0.5 0.6955 0.9999 1724015 ChemDiv1_005812 CCN(CC)CCNc1nc2nonc2nc1NCCN(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I05 compound treatment 283.7 95.4 0.5 279.2 92.4 0.48 0.6918 0.9998 1950576 ChemDiv1_005813 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I06 compound treatment 281.6 93.3 0.49 282.9 96.1 0.5 0.6977 0.9999 1453232 ChemDiv1_005814 CCn1c(SCC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)nc4n(C)c(=O)n(C)c(=O)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I07 compound treatment 281.7 93.4 0.49 284.0 97.2 0.51 0.7021 0.9998 1382081 ChemDiv1_005815 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I08 compound treatment 285.0 96.7 0.5 277.5 90.7 0.47 0.6904 0.9994 1407405 ChemDiv1_005816 Cn1c(=O)n(C)c2ncn(CC(=O)NCc3ccccc3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I09 compound treatment 281.3 93.0 0.49 282.2 95.4 0.5 0.694 0.9999 1973041 ChemDiv1_005817 CCOC(=O)C1=C(C)C2C3C(C(=O)N(C3=O)c4ccccc4C)C1(C)C5C2C(=O)N(C5=O)c6ccccc6C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I10 compound treatment 281.7 93.4 0.49 284.2 97.4 0.51 0.7028 0.9998 1604905 ChemDiv1_005818 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I11 compound treatment 280.1 91.8 0.48 281.8 95.0 0.49 0.6881 0.9999 1973042 ChemDiv1_005819 CCCC/1=NN(C(=O)\C1=C(\C)/N2CCOCC2)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I12 compound treatment 277.2 88.9 0.46 281.7 94.9 0.49 0.6771 0.9995 1973043 ChemDiv1_005820 Cn1cnnc1SCC(=O)NC2=NCCS2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I13 compound treatment 276.7 88.4 0.46 279.3 92.5 0.48 0.6664 0.9998 1528228 ChemDiv1_005821 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OCC(=O)N5CCCCC5)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I14 compound treatment 285.9 97.6 0.51 284.7 97.9 0.51 0.7202 1.0 1948361 ChemDiv1_005822 COc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(O)c(O)c3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I15 compound treatment 277.2 88.9 0.46 279.9 93.1 0.48 0.6704 0.9998 1618722 ChemDiv1_005823 COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(n2)N4CCNCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I16 compound treatment 276.1 87.8 0.46 278.3 91.5 0.48 0.6605 0.9998 1187099 ChemDiv1_005824 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCc3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I17 compound treatment 278.8 90.5 0.47 277.0 90.2 0.47 0.6657 1.0 1973044 ChemDiv1_005825 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc4OCOc4cc3[N+](=O)[O-])/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I18 compound treatment 280.2 91.9 0.48 278.0 91.2 0.47 0.6745 1.0 1351712 ChemDiv1_005826 CCOC(=O)C1=C(C)NC(=C(C#N)C1CC(C)C)SCC(=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I19 compound treatment 279.8 91.5 0.48 278.1 91.3 0.47 0.6734 1.0 1973045 ChemDiv1_005827 COc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cc(OC)c(O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I20 compound treatment 280.6 92.3 0.48 281.7 94.9 0.49 0.6896 0.9999 1973046 ChemDiv1_005828 COc1cccc(c1)N2C(=O)/C(=C/c3ccc(OC)c4ccccc34)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I21 compound treatment 275.6 87.3 0.46 276.5 89.7 0.47 0.652 0.9999 1973047 ChemDiv1_005829 CCc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccco3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I22 compound treatment 278.1 89.8 0.47 274.6 87.8 0.46 0.6543 0.9999 1661310 ChemDiv1_005830 CC1CCN(CN2C(=O)C3(SCC(=O)N3c4ccc(C)c(C)c4)c5ccccc25)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I23 mock treatment 276.0 87.7 0.46 273.3 86.5 0.45 0.6418 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 I24 mock treatment 69.5 -119.0 -0.62 82.2 -105.0 -0.54 -0.8224 -0.9979 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J01 compound treatment 280.3 92.0 0.48 289.5 103.0 0.53 0.7172 0.9986 1973048 ChemDiv1_005831 CN1C(=O)N(C)C(=O)C(=Cc2ccc(N3CCc4ccccc4C3)c(c2)[N+](=O)[O-])C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J02 compound treatment 283.8 95.5 0.5 284.7 97.9 0.51 0.7124 0.9999 1264957 ChemDiv1_005832 Cn1c(SCc2nc3ccccc3n2CC(=O)N)nc4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J03 compound treatment 274.1 85.8 0.45 272.6 85.8 0.45 0.6322 1.0 1384870 ChemDiv1_005833 Nc1nc(SCc2ccccc2)c(C#N)c(c1C#N)c3ccc(O)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J04 compound treatment 281.9 93.6 0.49 282.1 95.3 0.5 0.6959 1.0 1973049 ChemDiv1_005834 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(N4CCOCC4)c(c3)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J05 compound treatment 282.9 94.6 0.49 282.9 96.1 0.5 0.7025 1.0 1784758 ChemDiv1_005835 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J06 compound treatment 281.9 93.6 0.49 285.5 98.7 0.51 0.7084 0.9997 1973050 ChemDiv1_005836 CCOc1ccccc1NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J07 compound treatment 276.3 88.0 0.46 284.6 97.8 0.51 0.6844 0.9987 1144035 ChemDiv1_005837 COc1cc(cc(OC)c1OC)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J08 compound treatment 285.4 97.1 0.51 286.2 99.4 0.52 0.7238 1.0 1950341 ChemDiv1_005838 CC1CN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC(C)O1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J09 compound treatment 278.2 89.9 0.47 279.9 93.1 0.48 0.6741 0.9999 1973051 ChemDiv1_005839 CC(C)Nc1nc(Cl)nc(Nc2cccc(c2)C(F)(F)F)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J10 compound treatment 276.2 87.9 0.46 279.8 93.0 0.48 0.6664 0.9997 1926396 ChemDiv1_005840 COC(=O)CN1C(=O)/C(=C/c2ccc(OCc3ccccc3Cl)c(OC)c2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J11 compound treatment 283.2 94.9 0.5 283.4 96.6 0.5 0.7054 1.0 1632333 ChemDiv1_005841 Cc1cccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J12 compound treatment 269.4 81.1 0.42 266.2 79.4 0.41 0.5913 0.9999 1944129 ChemDiv1_005842 On1c(=O)c(c2ccccc2)[n+]([O-])c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J13 compound treatment 277.6 89.3 0.47 279.6 92.8 0.48 0.6708 0.9998 1973052 ChemDiv1_005843 [O-][N+](=O)c1cccc(c1)C(C2C(=O)NC(=S)N(CC=C)C2=O)C3C(=O)NC(=S)N(CC=C)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J14 compound treatment 280.9 92.6 0.48 278.1 91.3 0.47 0.6775 1.0 1784512 ChemDiv1_005844 CCOn1c(=O)c(C)[n+]([O-])c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J15 compound treatment 281.1 92.8 0.48 280.1 93.3 0.49 0.6856 1.0 1344280 ChemDiv1_005845 Cc1ccc(Nc2nc3nonc3nc2NC(C)(C)C)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J16 compound treatment 279.8 91.5 0.48 280.8 94.0 0.49 0.6833 0.9999 1561938 ChemDiv1_005846 NC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J17 compound treatment 278.8 90.5 0.47 282.1 95.3 0.5 0.6844 0.9997 1973053 ChemDiv1_005847 Nc1nc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])c(C#N)c(c3ccco3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J18 compound treatment 283.3 95.0 0.5 278.2 91.4 0.48 0.6867 0.9998 1973054 ChemDiv1_005848 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J19 compound treatment 278.2 89.9 0.47 277.1 90.3 0.47 0.6638 1.0 1973055 ChemDiv1_005849 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)C(C)(C)C)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J20 compound treatment 278.4 90.1 0.47 279.6 92.8 0.48 0.6738 0.9999 1235295 ChemDiv1_005850 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(Cl)cc3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J21 compound treatment 284.1 95.8 0.5 287.4 101.0 0.52 0.7235 0.9997 1973056 ChemDiv1_005851 CC/N=C/1\S/C(=C/c2ccc(o2)c3ccc(Cl)cc3C(=O)O)/C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J22 compound treatment 278.4 90.1 0.47 276.5 89.7 0.47 0.6624 1.0 1143276 ChemDiv1_005852 Cc1ccc2NC(=O)C(O)(C3COC(C)(C)CC3=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J23 mock treatment 283.3 95.0 0.5 278.3 91.5 0.48 0.6871 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 J24 mock treatment 78.1 -110.0 -0.57 76.7 -110.0 -0.57 -0.8109 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K01 compound treatment 280.3 92.0 0.48 282.0 95.2 0.5 0.6896 0.9999 1973057 ChemDiv1_005853 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K02 compound treatment 284.1 95.8 0.5 283.5 96.7 0.5 0.7091 1.0 1973058 ChemDiv1_005854 O=C1C2CC=CCC2C(=O)N1c3ccc(cc3)c4nc5cc(ccc5[nH]4)N6C(=O)C7CC=CCC7C6=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K03 compound treatment 281.8 93.5 0.49 282.2 95.4 0.5 0.6959 1.0 1973059 ChemDiv1_005855 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc([N+](=O)[O-])c(Cl)c4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K04 compound treatment 282.8 94.5 0.49 286.1 99.3 0.52 0.7139 0.9997 1396082 ChemDiv1_005856 C(Nc1nc2nonc2nc1NCc3ccco3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K05 compound treatment 282.9 94.6 0.49 282.1 95.3 0.5 0.6996 1.0 1223920 ChemDiv1_005857 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K06 compound treatment 278.0 89.7 0.47 282.5 95.7 0.5 0.6829 0.9995 1672960 ChemDiv1_005858 O=C1c2ccccc2-c3nn(c4ccccc4)c(=O)c5ccc(N6CCCCC6)c1c35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K07 compound treatment 281.1 92.8 0.48 282.7 95.9 0.5 0.6951 0.9999 1226654 ChemDiv1_005859 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc(C)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K08 compound treatment 277.8 89.5 0.47 279.4 92.6 0.48 0.6708 0.9999 1928106 ChemDiv1_005860 Brc1ccc(cc1)C(=O)CSc2nnc[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K09 compound treatment 282.0 93.7 0.49 281.8 95.0 0.49 0.6951 1.0 1973060 ChemDiv1_005861 CCOC(=O)C1=C(C)C2C3C(C(=O)N(C3=O)c4ccccc4F)C1(C)C5C2C(=O)N(C5=O)c6ccccc6F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K10 compound treatment 282.4 94.1 0.49 283.4 96.6 0.5 0.7025 0.9999 1583509 ChemDiv1_005862 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccc(OC(=O)N4CCOCC4)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K11 compound treatment 291.6 103.0 0.54 288.1 101.0 0.53 0.7537 0.9999 1973061 ChemDiv1_005863 COc1ccc(cc1)C2CC(=NN2c3ccccc3)c4c(C)cc(C)[nH]c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K12 compound treatment 284.2 95.9 0.5 278.9 92.1 0.48 0.6926 0.9998 1320014 ChemDiv1_005864 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3cc(Cl)cc(Cl)c3OC(=O)N4CCOCC4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K13 compound treatment 276.0 87.7 0.46 279.9 93.1 0.48 0.666 0.9996 1473664 ChemDiv1_005865 CCN(c1ccccc1)c2nc3nonc3nc2NCCO 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K14 compound treatment 278.5 90.2 0.47 289.4 103.0 0.53 0.7102 0.9981 1742549 ChemDiv1_005866 CC(C)c1ccc(cc1)c2c(C#N)c(N)nc(SC3CCCCC3=O)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K15 compound treatment 278.5 90.2 0.47 281.5 94.7 0.49 0.6811 0.9997 1455489 ChemDiv1_005867 CC(Nc1nc2nonc2nc1N3CCCC3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K16 compound treatment 281.6 93.3 0.49 278.5 91.7 0.48 0.6815 0.9999 1396915 ChemDiv1_005868 CCOc1ccccc1C2CC(=O)NC(=C2C#N)SCc3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K17 compound treatment 279.8 91.5 0.48 280.6 93.8 0.49 0.6826 0.9999 1973062 ChemDiv1_005869 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc(OC)c(O)c(OC)c3)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K18 compound treatment 280.0 91.7 0.48 284.8 98.0 0.51 0.6988 0.9995 1973063 ChemDiv1_005870 COc1cc(ccc1OCc2ccccc2)C3CC(=O)NC(=C3C#N)SCC(=O)Nc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K19 compound treatment 277.0 88.7 0.46 278.1 91.3 0.47 0.6631 0.9999 1973064 ChemDiv1_005871 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cccc(OC)c3OC)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K20 compound treatment 278.2 89.9 0.47 279.5 92.7 0.48 0.6727 0.9999 1973065 ChemDiv1_005872 COc1cccc(c1)N2C(=O)/C(=C/c3ccc(OC)c(OC)c3OC)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K21 compound treatment 300.2 112.0 0.58 286.7 99.9 0.52 0.7803 0.9983 1420386 ChemDiv1_005873 COc1cc(C=c2sc3nc4ccccc4n3c2=O)c(Br)cc1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K22 compound treatment 277.8 89.5 0.47 276.0 89.2 0.46 0.6583 1.0 1597975 ChemDiv1_005874 O=C(CSc1nc2ccc(cc2s1)N3C(=O)C4C5CC(C=C5)C4C3=O)NC6CCCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K23 mock treatment 282.1 93.8 0.49 282.3 95.5 0.5 0.6973 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 K24 mock treatment 80.5 -108.0 -0.56 77.1 -110.0 -0.57 -0.8005 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L01 compound treatment 285.0 96.7 0.5 291.3 105.0 0.54 0.7411 0.9993 1241989 ChemDiv1_005875 CCOc1cc(C=c2sc3nc4c(C)c(C)ccc4n3c2=O)cc(Br)c1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L02 compound treatment 280.8 92.5 0.48 281.8 95.0 0.49 0.6907 0.9999 1973066 ChemDiv1_005876 OCC(O)Cn1c(SCCOc2ccc(Cl)cc2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L03 compound treatment 285.0 96.7 0.5 279.7 92.9 0.48 0.6985 0.9998 1319586 ChemDiv1_005877 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(C)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L04 compound treatment 280.3 92.0 0.48 280.3 93.5 0.49 0.6833 1.0 1564150 ChemDiv1_005878 NC1=C(C#N)C2(C(=O)Nc3ccc(Cl)cc32)c4c(n[nH]c4O1)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L05 compound treatment 285.3 97.0 0.51 282.0 95.2 0.5 0.708 0.9999 1404796 ChemDiv1_005879 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L06 compound treatment 284.6 96.3 0.5 283.2 96.4 0.5 0.7099 1.0 1973067 ChemDiv1_005880 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3ccccc3[N+](=O)[O-])C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L07 compound treatment 283.1 94.8 0.49 281.8 95.0 0.49 0.6992 1.0 1197177 ChemDiv1_005881 Cc1ccc(Nc2nc3nonc3nc2NCCc4ccccc4)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L08 compound treatment 281.4 93.1 0.49 281.6 94.8 0.49 0.6922 1.0 1941587 ChemDiv1_005882 COc1ccccc1c2c(oc3c(CN4CC(C)OC(C)C4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L09 compound treatment 287.1 98.8 0.52 284.1 97.3 0.51 0.7224 1.0 1973068 ChemDiv1_005883 FC(F)(F)c1cccc(Nc2nc(Cl)nc(NCc3ccco3)n2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L10 compound treatment 279.7 91.4 0.48 278.6 91.8 0.48 0.6749 1.0 1973069 ChemDiv1_005884 Cc1ccc(Cc2cnc(NC(=O)/C(=C/c3ccc(OCC=C)cc3)/C#N)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L11 compound treatment 279.9 91.6 0.48 282.4 95.6 0.5 0.6896 0.9998 1604923 ChemDiv1_005885 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L12 compound treatment 280.3 92.0 0.48 276.9 90.1 0.47 0.6708 0.9999 1925984 ChemDiv1_005886 COn1c(=O)c(c2ccccc2)[n+]([O-])c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L13 compound treatment 278.9 90.6 0.47 282.0 95.2 0.5 0.6844 0.9997 1973070 ChemDiv1_005887 COc1cc(OC)c(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L14 compound treatment 279.4 91.1 0.48 280.0 93.2 0.48 0.6789 1.0 1650900 ChemDiv1_005888 Clc1cccc(Nc2nc(nc3ccccc23)c4ccncc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L15 compound treatment 303.5 115.0 0.6 301.7 115.0 0.6 0.8476 1.0 1416543 ChemDiv1_005889 CN(C)C(=O)Oc1cccc(c1)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L16 compound treatment 278.1 89.8 0.47 279.1 92.3 0.48 0.6708 0.9999 1469233 ChemDiv1_005890 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L17 compound treatment 282.8 94.5 0.49 283.7 96.9 0.5 0.7051 0.9999 1230289 ChemDiv1_005891 CC(C)c1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)Nc4nccs4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L18 compound treatment 281.3 93.0 0.49 280.5 93.7 0.49 0.6878 1.0 1434749 ChemDiv1_005892 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L19 compound treatment 281.6 93.3 0.49 282.6 95.8 0.5 0.6966 0.9999 1973071 ChemDiv1_005893 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4c(F)cccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L20 compound treatment 282.4 94.1 0.49 276.2 89.4 0.46 0.676 0.9996 1395410 ChemDiv1_005894 Cc1cc(Br)ccc1NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L21 compound treatment 278.3 90.0 0.47 275.2 88.4 0.46 0.6572 0.9999 1973072 ChemDiv1_005895 COc1ccc(NC(=O)CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L22 compound treatment 279.3 91.0 0.47 275.9 89.1 0.46 0.6635 0.9999 1636489 ChemDiv1_005896 CN1C(=O)C(O)(C2COC(C)(C)CC2=O)c3cc(C)ccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L23 mock treatment 279.2 90.9 0.47 278.2 91.4 0.48 0.6716 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 L24 mock treatment 80.8 -107.0 -0.56 75.0 -112.0 -0.58 -0.8071 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M01 compound treatment 283.2 94.9 0.5 281.7 94.9 0.49 0.6992 1.0 1973073 ChemDiv1_005897 Fc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M02 compound treatment 281.3 93.0 0.49 282.0 95.2 0.5 0.6933 1.0 1973074 ChemDiv1_005898 Cc1ccc2[nH]c(SCC(=O)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M03 compound treatment 282.5 94.2 0.49 282.5 95.7 0.5 0.6995 1.0 1348261 ChemDiv1_005899 CCCCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M04 compound treatment 281.9 93.6 0.49 280.6 93.8 0.49 0.6904 1.0 1973075 ChemDiv1_005900 CCc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)c(OC)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M05 compound treatment 285.0 96.7 0.5 281.6 94.8 0.49 0.7055 0.9999 1134690 ChemDiv1_005901 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccccc5C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M06 compound treatment 280.4 92.1 0.48 281.5 94.7 0.49 0.6881 0.9999 1973076 ChemDiv1_005902 CCOC(=O)COc1c(Br)cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M07 compound treatment 281.9 93.6 0.49 281.5 94.7 0.49 0.6937 1.0 1441546 ChemDiv1_005903 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)OCc3ccc(OC)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M08 compound treatment 287.1 98.8 0.52 281.2 94.4 0.49 0.7117 0.9997 1638225 ChemDiv1_005904 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M09 compound treatment 313.1 125.0 0.65 309.5 123.0 0.64 0.9117 0.9999 1973077 ChemDiv1_005905 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCC3CCCO3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M10 compound treatment 281.1 92.8 0.48 277.7 90.9 0.47 0.6767 0.9999 1973078 ChemDiv1_005906 CC(C)(C)c1n[nH]c2OC(=C(C#N)C(c12)c3ccccc3OC(=O)N4CCOCC4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M11 compound treatment 282.4 94.1 0.49 285.8 99.0 0.51 0.7113 0.9997 1973079 ChemDiv1_005907 COc1ccc(cc1)C2CC(=NN2c3ccccc3C)c4c(C)cc(C)[nH]c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M12 compound treatment 314.0 126.0 0.66 316.4 130.0 0.67 0.9403 0.9999 1489443 ChemDiv1_005908 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3[nH]2)sc4CN(C)CCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M13 compound treatment 277.6 89.3 0.47 276.8 90.0 0.47 0.6605 1.0 1973080 ChemDiv1_005909 CCCCOC(=O)c1ccc(NC(=O)CSc2nc3ccccc3n2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M14 compound treatment 292.3 104.0 0.54 299.3 113.0 0.59 0.7974 0.9993 1594030 ChemDiv1_005910 Cc1ccccc1NC(=O)c2c(C)nc(SCC(=O)c3ccc(O)c(O)c3)c(C#N)c2c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M15 compound treatment 276.9 88.6 0.46 279.8 93.0 0.48 0.669 0.9997 1973081 ChemDiv1_005911 COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(C)c3)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M16 compound treatment 279.9 91.6 0.48 277.3 90.5 0.47 0.6708 1.0 1202340 ChemDiv1_005912 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M17 compound treatment 279.1 90.8 0.47 276.0 89.2 0.46 0.6631 0.9999 1973082 ChemDiv1_005913 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M18 compound treatment 280.5 92.2 0.48 279.0 92.2 0.48 0.6793 1.0 1654233 ChemDiv1_005914 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(OCc3ccccc3)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M19 compound treatment 275.4 87.1 0.45 282.5 95.7 0.5 0.6734 0.999 1973083 ChemDiv1_005915 COc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M20 compound treatment 279.0 90.7 0.47 278.2 91.4 0.48 0.6708 1.0 1973084 ChemDiv1_005916 COc1ccccc1N2C(=O)NC(=O)/C(=C\c3ccc(OC)c4ccccc34)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M21 compound treatment 283.3 95.0 0.5 282.5 95.7 0.5 0.7025 1.0 1973085 ChemDiv1_005917 Fc1cccc(Cl)c1Cn2cc(C=C3C(=O)NC(=S)NC3=O)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M22 compound treatment 279.1 90.8 0.47 277.8 91.0 0.47 0.6697 1.0 1973086 ChemDiv1_005918 COC(=O)c1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5cccc([N+](=O)[O-])c5C4=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M23 mock treatment 281.2 92.9 0.48 277.9 91.1 0.47 0.6778 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 M24 mock treatment 192.8 4.54 0.02 183.8 -2.96 -0.02 0.0059 0.2087 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N01 compound treatment 283.0 94.7 0.49 284.5 97.7 0.51 0.7087 0.9999 1402720 ChemDiv1_005919 CCOC(=O)c1c(NC(=O)c2ccc(OC)c(c2)S(=O)(=O)N3CCOCC3)sc4CCCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N02 compound treatment 283.6 95.3 0.5 281.7 94.9 0.49 0.7007 1.0 1973087 ChemDiv1_005920 NC(=O)Cn1c(SCCOc2ccc(Cl)cc2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N03 compound treatment 283.2 94.9 0.5 279.5 92.7 0.48 0.6911 0.9999 1148752 ChemDiv1_005921 COc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cc(C)ccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N04 compound treatment 279.8 91.5 0.48 282.4 95.6 0.5 0.6892 0.9998 1406793 ChemDiv1_005922 COc1cccc(NC(=O)CSc2nnc(SCC(=O)Nc3cccc(OC)c3)s2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N05 compound treatment 281.1 92.8 0.48 282.1 95.3 0.5 0.6929 0.9999 1434879 ChemDiv1_005923 CCN1C(=O)C2(C(=C(N)Oc3[nH]nc(c32)c4ccccc4)C#N)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N06 compound treatment 289.3 101.0 0.53 285.8 99.0 0.51 0.7368 0.9999 1973088 ChemDiv1_005924 CCc1nnc(NC(=O)CN2C(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/SC2=S)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N07 compound treatment 277.6 89.3 0.47 281.6 94.8 0.49 0.6782 0.9996 1588058 ChemDiv1_005925 CC1(COC2(OC1)C(=O)N(CN3CCN(Cc4ccccc4)CC3)c5ccccc52)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N08 compound treatment 281.1 92.8 0.48 280.5 93.7 0.49 0.687 1.0 1431459 ChemDiv1_005926 Clc1ccccc1Nc2ncnc3ccc(Br)cc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N09 compound treatment 284.0 95.7 0.5 280.2 93.4 0.49 0.6966 0.9999 1539996 ChemDiv1_005927 CC1CCCN(CN2C(=O)C3(OCC(C)(CO3)c4ccccc4)c5ccccc25)C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N10 compound treatment 278.8 90.5 0.47 281.6 94.8 0.49 0.6826 0.9998 1973089 ChemDiv1_005928 Cc1ccc(Cc2cnc(NC(=O)/C(=C\c3ccc(o3)c4ccc(F)cc4)/C#N)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N11 compound treatment 280.0 91.7 0.48 286.2 99.4 0.52 0.7039 0.9993 1973090 ChemDiv1_005929 Cc1ccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N12 compound treatment 281.2 92.9 0.48 278.8 92.0 0.48 0.6812 1.0 1973091 ChemDiv1_005930 CCOC(=O)COn1c(=O)c(c2ccccc2)[n+]([O-])c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N13 compound treatment 278.3 90.0 0.47 275.0 88.2 0.46 0.6565 0.9999 1973092 ChemDiv1_005931 COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3C)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N14 compound treatment 279.7 91.4 0.48 281.2 94.4 0.49 0.6844 0.9999 1267611 ChemDiv1_005932 Clc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N15 compound treatment 283.8 95.5 0.5 285.2 98.4 0.51 0.7143 0.9999 1429757 ChemDiv1_005933 NC1=C(C#N)C2(C(=O)Nc3ccc(Br)cc32)C4=C(CC(CC4=O)c5ccccc5)O1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N16 compound treatment 282.6 94.3 0.49 282.7 95.9 0.5 0.7007 1.0 1332457 ChemDiv1_005934 COc1ccc(cc1)n2c(SCC(=O)N)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N17 compound treatment 277.6 89.3 0.47 280.2 93.4 0.49 0.673 0.9998 1973093 ChemDiv1_005935 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccc(s4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N18 compound treatment 277.2 88.9 0.46 280.9 94.1 0.49 0.6741 0.9996 1125562 ChemDiv1_005936 Cc1cccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N19 compound treatment 277.0 88.7 0.46 280.9 94.1 0.49 0.6734 0.9996 1717881 ChemDiv1_005937 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(OC)cc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N20 compound treatment 280.5 92.2 0.48 276.1 89.3 0.46 0.6686 0.9998 1228410 ChemDiv1_005938 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3cccc(F)c3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N21 compound treatment 275.5 87.2 0.46 272.9 86.1 0.45 0.6384 1.0 1973094 ChemDiv1_005939 COC(=O)C(C)Sc1nnc(o1)c2ccncc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N22 compound treatment 282.5 94.2 0.49 277.3 90.5 0.47 0.6804 0.9998 1947459 ChemDiv1_005940 COc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccc(F)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N23 mock treatment 279.1 90.8 0.47 278.3 91.5 0.48 0.6716 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 N24 mock treatment 191.7 3.44 0.02 192.4 5.64 0.03 0.0334 0.9723 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O01 compound treatment 283.5 95.2 0.5 280.7 93.9 0.49 0.6966 1.0 1377390 ChemDiv1_005941 Cc1nc2ccccc2c(=O)n1OC(=O)c3ccc(cc3)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O02 compound treatment 281.7 93.4 0.49 284.5 97.7 0.51 0.7039 0.9998 1603342 ChemDiv1_005942 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(OC(=O)c4ccccc4)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O03 compound treatment 282.6 94.3 0.49 279.5 92.7 0.48 0.6889 0.9999 1153169 ChemDiv1_005943 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc3OCOc3c2)C(=O)Nc4ccccc4C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O04 compound treatment 276.2 87.9 0.46 276.7 89.9 0.47 0.655 1.0 1305348 ChemDiv1_005944 OC(=O)c1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(F)cc4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O05 compound treatment 284.4 96.1 0.5 281.2 94.4 0.49 0.7018 0.9999 1475998 ChemDiv1_005945 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(OC)c5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O06 compound treatment 283.7 95.4 0.5 280.9 94.1 0.49 0.6981 1.0 1235464 ChemDiv1_005946 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(C#N)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O07 compound treatment 282.5 94.2 0.49 280.8 94.0 0.49 0.6933 1.0 1262142 ChemDiv1_005947 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O08 compound treatment 281.4 93.1 0.49 277.9 91.1 0.47 0.6786 0.9999 1354432 ChemDiv1_005948 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5ccccc5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O09 compound treatment 282.9 94.6 0.49 283.0 96.2 0.5 0.7029 1.0 1973095 ChemDiv1_005949 Cc1ccc(N/C=C\2/C(=O)N(N=C2CSc3ccc(C)cc3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O10 compound treatment 281.2 92.9 0.48 279.4 92.6 0.48 0.6834 1.0 1330581 ChemDiv1_005950 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(OC(=O)N4CCOCC4)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O11 compound treatment 279.1 90.8 0.47 277.6 90.8 0.47 0.669 1.0 1515972 ChemDiv1_005951 Cc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)NCCc4c[nH]c5ccccc45)c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O12 compound treatment 280.1 91.8 0.48 280.9 94.1 0.49 0.6848 0.9999 1251221 ChemDiv1_005952 O=C(CSc1cccc2cccnc12)Nc3nc4c(ccc5ccccc45)s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O13 compound treatment 275.6 87.3 0.46 275.2 88.4 0.46 0.6473 1.0 1973096 ChemDiv1_005953 CN(C)C(=O)C(Sc1nnc(c2ccc(Cl)cc2)n1c3ccccc3)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O14 compound treatment 284.5 96.2 0.5 282.3 95.5 0.5 0.7062 1.0 1410142 ChemDiv1_005954 COc1ccc(cc1)c2c(C#N)c(N)nc(SC3CCCCC3=O)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O15 compound treatment 284.1 95.8 0.5 281.6 94.8 0.49 0.7021 1.0 1973097 ChemDiv1_005955 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=O)N(Cc3ccc(OC)cc3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O16 compound treatment 274.3 86.0 0.45 280.3 93.5 0.49 0.6612 0.9992 1388075 ChemDiv1_005956 COC(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)OC(C)(C)C)c2ccc(Cl)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O17 compound treatment 284.6 96.3 0.5 280.6 93.8 0.49 0.7003 0.9999 1973098 ChemDiv1_005957 COc1cc(/C=C/2\C(=O)NC(=O)N(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O18 compound treatment 279.5 91.2 0.48 276.7 89.9 0.47 0.6672 1.0 1609194 ChemDiv1_005958 COC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(OC)c(OCc3ccccc3)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O19 compound treatment 280.4 92.1 0.48 278.1 91.3 0.47 0.6756 1.0 1782052 ChemDiv1_005959 CCOC(=O)c1c(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)sc3CC(CCc13)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O20 compound treatment 279.0 90.7 0.47 284.1 97.3 0.51 0.6925 0.9994 1973099 ChemDiv1_005960 COc1ccccc1N2C(=O)NC(=O)/C(=C\c3cc(OC)c(O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O21 compound treatment 278.0 89.7 0.47 275.9 89.1 0.46 0.6587 1.0 1913327 ChemDiv1_005961 FC(F)(F)C(=O)Nc1nnc([nH]1)c2nnc(NC(=O)C(F)(F)F)[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O22 compound treatment 277.3 89.0 0.46 276.4 89.6 0.47 0.6579 1.0 1530759 ChemDiv1_005962 O=C(CN1C(=O)c2ccccc2S1(=O)=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O23 mock treatment 277.9 89.6 0.47 281.8 95.0 0.49 0.68 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 O24 mock treatment 98.2 -90.1 -0.47 110.4 -76.4 -0.4 -0.6128 -0.9965 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P01 compound treatment 283.0 94.7 0.49 281.2 94.4 0.49 0.6966 1.0 1973100 ChemDiv1_005963 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc(cc3)[N+](=O)[O-])c4c(F)cccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P02 compound treatment 282.5 94.2 0.49 283.3 96.5 0.5 0.7025 0.9999 1650438 ChemDiv1_005964 CCCOc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P03 compound treatment 283.9 95.6 0.5 285.8 99.0 0.51 0.7168 0.9999 1784757 ChemDiv1_005965 Cc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)[N+](=O)[O-])c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P04 compound treatment 284.3 96.0 0.5 283.2 96.4 0.5 0.7088 1.0 1306347 ChemDiv1_005966 O=C(CC1SC(=O)NC1=O)Nc2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P05 compound treatment 281.0 92.7 0.48 281.9 95.1 0.49 0.6918 0.9999 1973101 ChemDiv1_005967 CCOc1cc(ccc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P06 compound treatment 281.0 92.7 0.48 278.6 91.8 0.48 0.6797 1.0 1950296 ChemDiv1_005968 Oc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P07 compound treatment 278.7 90.4 0.47 282.4 95.6 0.5 0.6852 0.9997 1283958 ChemDiv1_005969 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4cccc(OC(=O)N5CCOCC5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P08 compound treatment 283.7 95.4 0.5 283.4 96.6 0.5 0.7073 1.0 1941168 ChemDiv1_005970 CC(=O)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P09 compound treatment 279.1 90.8 0.47 280.9 94.1 0.49 0.6811 0.9999 1973102 ChemDiv1_005971 Brc1ccc(CN2CCN(CCNC(=O)C(=O)Nc3ccccc3)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P10 compound treatment 283.7 95.4 0.5 284.7 97.9 0.51 0.7121 0.9999 1973103 ChemDiv1_005972 Cc1ccc(Cc2cnc(NC(=O)/C(=C\c3ccc(o3)c4ccc(cc4)[N+](=O)[O-])/C#N)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P11 compound treatment 279.2 90.9 0.47 281.6 94.8 0.49 0.6841 0.9998 1456147 ChemDiv1_005973 NS(=O)(=O)c1ccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P12 compound treatment 279.1 90.8 0.47 276.8 90.0 0.47 0.6661 1.0 1973104 ChemDiv1_005974 Cc1[n+]([O-])c2ccccc2n(OCc3ccccc3)c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P13 compound treatment 277.0 88.7 0.46 279.6 92.8 0.48 0.6686 0.9998 1973105 ChemDiv1_005975 COc1ccc2ccccc2c1/C=C/3\C(=O)NC(=O)N(C3=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P14 compound treatment 279.4 91.1 0.48 282.9 96.1 0.5 0.6896 0.9997 1172751 ChemDiv1_005976 Brc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P15 compound treatment 279.0 90.7 0.47 279.8 93.0 0.48 0.6767 0.9999 1973106 ChemDiv1_005977 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc(OC(=O)N5CCOCC5)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P16 compound treatment 275.5 87.2 0.46 281.0 94.2 0.49 0.6682 0.9993 1649547 ChemDiv1_005978 Cc1cccc(c1)n2c(SCC(=O)N)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P17 compound treatment 275.8 87.5 0.46 280.6 93.8 0.49 0.6679 0.9995 1606823 ChemDiv1_005979 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4ccc(OC(=O)c5ccco5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P18 compound treatment 281.1 92.8 0.48 282.6 95.8 0.5 0.6948 0.9999 1414985 ChemDiv1_005980 Cc1c(Cl)cccc1NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P19 compound treatment 280.2 91.9 0.48 280.1 93.3 0.49 0.6822 1.0 1973107 ChemDiv1_005981 Clc1ccccc1CN2CCN(CCNC(=O)C(=O)Nc3ccc(Br)cc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P20 compound treatment 280.4 92.1 0.48 278.2 91.4 0.48 0.676 1.0 1783036 ChemDiv1_005982 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(F)c(c3)[N+](=O)[O-])c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P21 compound treatment 279.4 91.1 0.48 282.4 95.6 0.5 0.6877 0.9998 1633451 ChemDiv1_005983 Clc1nc(NCc2ccco2)nc(n1)N3CCC(Cc4ccccc4)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P22 compound treatment 279.2 90.9 0.47 279.4 92.6 0.48 0.676 1.0 1947799 ChemDiv1_005984 COc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P23 mock treatment 277.9 89.6 0.47 278.0 91.2 0.47 0.666 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.603 P24 mock treatment 108.6 -79.7 -0.42 98.6 -88.2 -0.46 -0.6179 -0.9988 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A01 compound treatment 285.2 99.0 0.52 287.8 102.0 0.53 0.7405 0.9999 1947446 ChemDiv1_005985 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N\c4ccccc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A02 compound treatment 282.0 95.8 0.5 283.2 97.5 0.51 0.7117 1.0 1481169 ChemDiv1_005986 CCOC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A03 compound treatment 282.4 96.2 0.5 282.7 97.0 0.5 0.7114 1.0 1488783 ChemDiv1_005987 Clc1cccc(NC(=O)Nc2nc(cs2)c3ccccc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A04 compound treatment 281.6 95.4 0.5 280.2 94.5 0.49 0.6992 1.0 1278626 ChemDiv1_005988 COC(=O)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC(=C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A05 compound treatment 282.2 96.0 0.5 282.8 97.1 0.5 0.711 1.0 1253323 ChemDiv1_005989 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3cc(C)ccc3C)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A06 compound treatment 278.6 92.4 0.48 280.2 94.5 0.49 0.6882 1.0 1973108 ChemDiv1_005990 CCOC(=O)c1c(C)n(CC(COC(=O)C)OC(=O)C)c2ccc(OC(=O)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A07 compound treatment 277.4 91.2 0.48 279.1 93.4 0.49 0.6797 0.9999 1973109 ChemDiv1_005991 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(ccc3Cl)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A08 compound treatment 284.3 98.1 0.51 282.3 96.6 0.5 0.7169 1.0 1947556 ChemDiv1_005992 CC(=O)OCc1c(OC(=O)C)ccc2c([N+](=O)[O-])c(C)n(c3ccc(C)cc3)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A09 compound treatment 282.0 95.8 0.5 280.3 94.6 0.49 0.7011 1.0 1973110 ChemDiv1_005993 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3cccc(c3)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A10 compound treatment 278.2 92.0 0.48 282.4 96.7 0.5 0.6948 0.9997 1973111 ChemDiv1_005994 COc1ccc(cc1)c2cc(c(C#N)c(N)n2)c3cccc(Br)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A11 compound treatment 282.1 95.9 0.5 281.4 95.7 0.5 0.7055 1.0 1519849 ChemDiv1_005995 Cc1ccn2cc(nc2c1)c3cccc(NC(=O)c4cc5cc(Br)ccc5oc4=O)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A12 compound treatment 273.8 87.6 0.46 276.0 90.3 0.47 0.655 0.9999 1973112 ChemDiv1_005996 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc6OCOc6cc5[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A13 compound treatment 278.9 92.7 0.48 278.5 92.8 0.48 0.683 1.0 1681646 ChemDiv1_005997 COc1ccc(Cl)cc1C(=O)On2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A14 compound treatment 279.3 93.1 0.49 279.4 93.7 0.49 0.6878 1.0 1412711 ChemDiv1_005998 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(F)c(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A15 compound treatment 272.4 86.2 0.45 282.6 96.9 0.5 0.6741 0.9984 1973113 ChemDiv1_005999 CCOC(=O)CSc1nc2sc3CC(CCc3c2c(=O)[nH]1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A16 compound treatment 273.8 87.6 0.46 270.3 84.6 0.44 0.6341 0.9998 1185413 ChemDiv1_006000 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(Cl)c2)C(=O)Nc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A17 compound treatment 283.2 97.0 0.51 284.9 99.2 0.52 0.7224 1.0 1786017 ChemDiv1_006001 CCn1c(=O)c2c3CCN(C)Cc3sc2[nH]c1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A18 compound treatment 280.0 93.8 0.49 276.2 90.5 0.47 0.6786 0.9998 1532603 ChemDiv1_006002 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A19 compound treatment 276.0 89.8 0.47 278.2 92.5 0.48 0.6712 0.9999 1973114 ChemDiv1_006003 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A20 compound treatment 276.7 90.5 0.47 278.6 92.9 0.48 0.6753 0.9999 1718388 ChemDiv1_006004 COc1cc(ccc1OC(=O)C)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A21 compound treatment 273.7 87.5 0.46 277.5 91.8 0.48 0.6602 0.9998 1933565 ChemDiv1_006005 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A22 compound treatment 274.4 88.2 0.46 273.9 88.2 0.46 0.6495 1.0 1973115 ChemDiv1_006006 C(C1CCN(CC1)c2nc3nonc3nc2Nc4ccc5OCOc5c4)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A23 mock treatment 279.3 93.1 0.49 277.3 91.6 0.48 0.6801 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 A24 mock treatment 74.5 -112.0 -0.58 74.2 -112.0 -0.58 -0.8219 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B01 compound treatment 282.5 96.3 0.5 283.1 97.4 0.51 0.7132 1.0 1973116 ChemDiv1_006007 Oc1c(CN2CCN(CC2)c3cccc(c3)C(F)(F)F)cc([N+](=O)[O-])c4cccnc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B02 compound treatment 280.6 94.4 0.49 279.5 93.8 0.49 0.693 1.0 1973117 ChemDiv1_006008 COC(=O)CC1SC(=O)NC1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B03 compound treatment 281.6 95.4 0.5 282.3 96.6 0.5 0.707 1.0 1973118 ChemDiv1_006009 CCCN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)/c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B04 compound treatment 281.1 94.9 0.5 282.9 97.2 0.51 0.7073 0.9999 1623729 ChemDiv1_006010 O=C(Nc1cccc2nsnc12)c3ccc4OCCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B05 compound treatment 279.8 93.6 0.49 281.0 95.3 0.5 0.6955 1.0 1973119 ChemDiv1_006011 CCCn1c(NC(=O)C)nc2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B06 compound treatment 276.0 89.8 0.47 276.8 91.1 0.47 0.6661 1.0 1973120 ChemDiv1_006012 O=C1c2ccccc2C(=O)c3c(cccc13)c4ccc(C=c5sc6nc7ccccc7n6c5=O)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B07 compound treatment 281.6 95.4 0.5 283.1 97.4 0.51 0.7099 1.0 1973121 ChemDiv1_006013 CCCC/1=NN(C(=O)\C1=C(/C)\NCCO)c2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B08 compound treatment 279.9 93.7 0.49 281.7 96.0 0.5 0.6985 0.9999 1358997 ChemDiv1_006014 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Cl)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B09 compound treatment 278.8 92.6 0.48 281.4 95.7 0.5 0.6933 0.9999 1973122 ChemDiv1_006015 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4ccc(Cl)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B10 compound treatment 286.1 99.9 0.52 285.0 99.3 0.52 0.7335 1.0 1973123 ChemDiv1_006016 FC(F)(F)c1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B11 compound treatment 291.7 106.0 0.55 291.4 106.0 0.55 0.7777 1.0 1973124 ChemDiv1_006017 CC1CCN(CC1)c2nc3c(C)cccn3c(=O)c2/C=C/4\SC(=S)N(Cc5ccccc5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B12 compound treatment 275.5 89.3 0.47 276.2 90.5 0.47 0.662 1.0 1188772 ChemDiv1_006018 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4ccc(Br)s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B13 compound treatment 289.6 103.0 0.54 291.9 106.0 0.55 0.7718 0.9999 1973125 ChemDiv1_006019 CN1CCN(CC1)c2nc3c(C)cccn3c(=O)c2/C=C/4\SC(=S)N(Cc5ccccc5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B14 compound treatment 277.0 90.8 0.47 275.2 89.5 0.47 0.6639 1.0 1394214 ChemDiv1_006020 COc1ccc(CNn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B15 compound treatment 279.3 93.1 0.49 278.0 92.3 0.48 0.6827 1.0 1395003 ChemDiv1_006021 CCCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B16 compound treatment 108.5 -77.7 -0.41 91.3 -94.4 -0.49 -0.6336 -0.9955 1445404 ChemDiv1_006022 CC1CCCN(Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23)C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B17 compound treatment 278.1 91.9 0.48 278.7 93.0 0.48 0.6808 1.0 1298832 ChemDiv1_006023 COc1ccc(cc1)c2nnc(Nc3c(C)n(C)n(c4ccccc4)c3=O)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B18 compound treatment 277.3 91.1 0.48 277.4 91.7 0.48 0.6731 1.0 1924804 ChemDiv1_006024 COCCOC(=O)c1c(C)oc2ccc(OCc3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B19 compound treatment 280.6 94.4 0.49 275.3 89.6 0.47 0.6775 0.9996 1216509 ChemDiv1_006025 CCOC(=O)Cc1nnc(Nc2ccc(OC)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B20 compound treatment 277.7 91.5 0.48 274.7 89.0 0.46 0.6646 0.9999 1584103 ChemDiv1_006026 COC(=O)c1c(C)oc2ccc(OC(=O)c3c(C)oc4ccc(OC(=O)C)cc34)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B21 compound treatment 278.9 92.7 0.48 276.8 91.1 0.47 0.6768 0.9999 1357985 ChemDiv1_006027 OCCNC(=O)c1ccc(cc1)c2nnc(N3CCOCC3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B22 compound treatment 273.5 87.3 0.46 273.8 88.1 0.46 0.6458 1.0 1405592 ChemDiv1_006028 CCOC(=O)c1c(C)oc2cc(Br)c(OCC(=O)c3ccc(OC)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B23 mock treatment 276.1 89.9 0.47 275.8 90.1 0.47 0.6628 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 B24 mock treatment 76.3 -110.0 -0.57 75.2 -111.0 -0.57 -0.8115 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C01 compound treatment 281.7 95.5 0.5 283.0 97.3 0.51 0.7099 1.0 1785884 ChemDiv1_006029 CCOc1cc(ccc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C02 compound treatment 280.4 94.2 0.49 280.7 95.0 0.49 0.6967 1.0 1973126 ChemDiv1_006030 CCn1c(SCc2ccccc2)nc3sc4COC(C)(C)Cc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C03 compound treatment 281.4 95.2 0.5 281.4 95.7 0.5 0.7029 1.0 1370836 ChemDiv1_006031 O=C(NC1CCCCC1)Nc2nc(cs2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C04 compound treatment 280.5 94.3 0.49 281.5 95.8 0.5 0.7 1.0 1973127 ChemDiv1_006032 COC(=O)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C05 compound treatment 280.6 94.4 0.49 283.4 97.7 0.51 0.7073 0.9999 1577212 ChemDiv1_006033 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C06 compound treatment 279.6 93.4 0.49 280.3 94.6 0.49 0.6922 1.0 1973128 ChemDiv1_006034 CCOC(=O)c1c(C)n(c2ccc(Cl)cc2)c3ccc(Oc4nccc(Nc5ccccc5)c4C#N)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C07 compound treatment 276.8 90.6 0.47 280.5 94.8 0.49 0.6826 0.9998 1927676 ChemDiv1_006035 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C08 compound treatment 275.8 89.6 0.47 279.4 93.7 0.49 0.6749 0.9998 1916527 ChemDiv1_006036 CN(C)Cc1c(O)ccc2c([N+](=O)[O-])c(/C=C/N(C)C)n(c3ccc(C)cc3)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C09 compound treatment 284.5 98.3 0.51 283.5 97.8 0.51 0.7221 1.0 1634848 ChemDiv1_006037 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C10 compound treatment 278.9 92.7 0.48 280.8 95.1 0.49 0.6915 0.9999 1730163 ChemDiv1_006038 CC(C)Cc1cc(c(C#N)c(O)n1)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C11 compound treatment 281.0 94.8 0.49 278.8 93.1 0.48 0.6919 0.9999 1254019 ChemDiv1_006039 Cc1nc(sc1C(=O)Nc2cccc(c2)c3cn4ccccc4n3)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C12 compound treatment 276.6 90.4 0.47 275.3 89.6 0.47 0.6628 1.0 1311863 ChemDiv1_006040 COc1cc(cc(Br)c1OC)C2Nc3cc(C)c(C)cc3NC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C13 compound treatment 278.6 92.4 0.48 282.2 96.5 0.5 0.6955 0.9998 1973129 ChemDiv1_006041 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccccc4F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C14 compound treatment 278.7 92.5 0.48 278.6 92.9 0.48 0.6827 1.0 1483240 ChemDiv1_006042 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccccc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C15 compound treatment 275.3 89.1 0.46 279.3 93.6 0.49 0.6727 0.9997 1669237 ChemDiv1_006043 Cc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C16 compound treatment 273.4 87.2 0.45 275.4 89.7 0.47 0.6514 0.9999 1973130 ChemDiv1_006044 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C17 compound treatment 281.2 95.0 0.5 278.5 92.8 0.48 0.6915 0.9999 1688044 ChemDiv1_006045 COc1ccc(cc1)n2c(=O)c3c4CCC(Cc4sc3[nH]c2=S)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C18 compound treatment 272.1 85.9 0.45 274.9 89.2 0.46 0.6447 0.9999 1309826 ChemDiv1_006046 CCOc1cc(ccc1OC(=O)C2CC2)C3Nc4cc(C)c(C)cc4NC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C19 compound treatment 274.2 88.0 0.46 276.9 91.2 0.47 0.6598 0.9999 1973131 ChemDiv1_006047 COC(=O)CSc1nnc2n(c3ccccc3)c(=O)c4c5CC(C)(C)OCc5sc4n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C20 compound treatment 275.7 89.5 0.47 274.3 88.6 0.46 0.6558 1.0 1528142 ChemDiv1_006048 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C21 compound treatment 279.1 92.9 0.48 280.2 94.5 0.49 0.69 1.0 1946371 ChemDiv1_006049 COC(=O)CSc1nnc2n(c3ccc(OC)cc3)c(=O)c4c5CC(C)(C)OCc5sc4n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C22 compound treatment 280.7 94.5 0.49 272.3 86.6 0.45 0.6669 0.999 1433318 ChemDiv1_006050 C(Nc1nc2nonc2nc1NCc3ccc4OCOc4c3)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C23 mock treatment 273.6 87.4 0.46 277.1 91.4 0.48 0.6583 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 C24 mock treatment 79.0 -107.0 -0.56 73.3 -112.0 -0.58 -0.8086 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D01 compound treatment 280.4 94.2 0.49 283.6 97.9 0.51 0.7073 0.9998 1973132 ChemDiv1_006051 Oc1c(cc(CN2CCN(CC2)c3cccc(c3)C(F)(F)F)c4cccnc14)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D02 compound treatment 287.6 101.0 0.53 287.1 101.0 0.53 0.7467 1.0 1281108 ChemDiv1_006052 CCOC(=O)c1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D03 compound treatment 285.3 99.1 0.52 283.5 97.8 0.51 0.725 1.0 1973133 ChemDiv1_006053 C/C(=C\1/C(=O)N(N=C1CSc2ccc(C)cc2)c3nc4ccccc4s3)/NCCN5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D04 compound treatment 281.5 95.3 0.5 284.3 98.6 0.51 0.7139 0.9999 1214369 ChemDiv1_006054 COc1cc(cc(OC)c1OC)C(=O)Nc2cc(ccc2C)c3nc4cc(Cl)cc(Cl)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D05 compound treatment 279.6 93.4 0.49 279.9 94.2 0.49 0.6908 1.0 1149271 ChemDiv1_006055 CCC(=O)Nc1nc2ccccc2n1Cc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D06 compound treatment 281.3 95.1 0.5 283.5 97.8 0.51 0.7103 0.9999 1973134 ChemDiv1_006056 Cc1ccc(cc1)S(=O)(=O)n2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D07 compound treatment 278.1 91.9 0.48 279.6 93.9 0.49 0.6841 1.0 1973135 ChemDiv1_006057 CC/1=NN(C(=O)\C1=C\NCCN2CCN(CC2)C(=S)NCC=C)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D08 compound treatment 275.3 89.1 0.46 279.2 93.5 0.49 0.6723 0.9998 1973136 ChemDiv1_006058 COc1cc(/C=C/C(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D09 compound treatment 281.5 95.3 0.5 284.5 98.8 0.51 0.7147 0.9999 1973137 ChemDiv1_006059 COc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D10 compound treatment 279.4 93.2 0.49 281.5 95.8 0.5 0.6959 0.9999 1973138 ChemDiv1_006060 Cc1cc(Br)ccc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D11 compound treatment 326.5 140.0 0.73 317.5 132.0 0.69 1.002 0.9995 1973139 ChemDiv1_006061 OCCN1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C/4\SC(=S)N(C5CCCCC5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D12 compound treatment 276.0 89.8 0.47 283.9 98.2 0.51 0.6922 0.9991 1520227 ChemDiv1_006062 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D13 compound treatment 269.7 83.5 0.44 288.5 103.0 0.53 0.6859 0.9949 1973140 ChemDiv1_006063 CC(N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(C)CC4)/SC1=S)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D14 compound treatment 276.8 90.6 0.47 276.2 90.5 0.47 0.6668 1.0 1973141 ChemDiv1_006064 COc1ccccc1/C=C/CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D15 compound treatment 278.5 92.3 0.48 279.3 93.6 0.49 0.6845 1.0 1973142 ChemDiv1_006065 CCCCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D16 compound treatment 136.9 -49.3 -0.26 150.9 -34.8 -0.18 -0.3098 -0.9852 1331060 ChemDiv1_006066 CC1CCN(Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D17 compound treatment 279.0 92.8 0.48 274.0 88.3 0.46 0.6669 0.9996 1549604 ChemDiv1_006067 CC(=O)Nc1ccc(Oc2nnc(c3ccc(C)cc3)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D18 compound treatment 275.1 88.9 0.46 277.0 91.3 0.47 0.6635 0.9999 1973143 ChemDiv1_006068 COC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D19 compound treatment 280.1 93.9 0.49 277.6 91.9 0.48 0.6842 0.9999 1553917 ChemDiv1_006069 COC(=O)Cc1nnc(Nc2cccc(C)c2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D20 compound treatment 273.4 87.2 0.45 272.7 87.0 0.45 0.6414 1.0 1929637 ChemDiv1_006070 Cc1csc(n1)c2cc3ccc(OCc4c(F)c(F)c(F)c(F)c4F)cc3oc2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D21 compound treatment 275.8 89.6 0.47 275.9 90.2 0.47 0.662 1.0 1282096 ChemDiv1_006071 OCCNC(=O)c1ccc(cc1)c2nnc(Nc3ccc(O)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D22 compound treatment 280.4 94.2 0.49 281.1 95.4 0.5 0.6981 1.0 1246059 ChemDiv1_006072 COc1ccc(cc1)C(=O)COc2cc3c(C(=O)OC(C)C)c(C)oc3cc2Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D23 mock treatment 275.3 89.1 0.46 274.5 88.8 0.46 0.6551 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 D24 mock treatment 78.2 -108.0 -0.56 76.2 -110.0 -0.57 -0.8009 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E01 compound treatment 285.0 98.8 0.52 282.2 96.5 0.5 0.7191 0.9999 1543733 ChemDiv1_006073 CCC(C)C(=O)N1C(C)CC(N(C(=O)COc2ccccc2)c3ccccc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E02 compound treatment 283.0 96.8 0.5 282.5 96.8 0.5 0.7129 1.0 1177834 ChemDiv1_006074 COc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E03 compound treatment 281.8 95.6 0.5 281.4 95.7 0.5 0.7044 1.0 1538593 ChemDiv1_006075 COc1ccc(cc1OC)C(NC(=O)Cc2ccccc2)c3ccc4cccnc4c3O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E04 compound treatment 287.0 101.0 0.53 289.8 104.0 0.54 0.7544 0.9999 1210289 ChemDiv1_006076 CCOC(=O)CSc1nc2sc3CN(C)CCc3c2c(=O)n1C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E05 compound treatment 280.9 94.7 0.49 285.8 100.0 0.52 0.7172 0.9997 1119689 ChemDiv1_006077 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E06 compound treatment 281.4 95.2 0.5 279.6 93.9 0.49 0.6963 1.0 1217122 ChemDiv1_006078 CCOC(=O)c1c(CN(C)C)n(c2ccccc2)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E07 compound treatment 278.4 92.2 0.48 279.2 93.5 0.49 0.6838 1.0 1973144 ChemDiv1_006079 COCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E08 compound treatment 285.5 99.3 0.52 285.9 100.0 0.52 0.7346 1.0 1586029 ChemDiv1_006080 COc1cc(ccc1O)C(C#N)N2N=C(CC2c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E09 compound treatment 282.5 96.3 0.5 283.5 97.8 0.51 0.7147 1.0 1141435 ChemDiv1_006081 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E10 compound treatment 279.2 93.0 0.49 284.4 98.7 0.51 0.7058 0.9996 1344690 ChemDiv1_006082 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E11 compound treatment 280.8 94.6 0.49 278.9 93.2 0.48 0.6915 1.0 1337531 ChemDiv1_006083 Cc1nc(sc1C(=O)Nc2cccc(c2)c3cn4ccc(C)cc4n3)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E12 compound treatment 277.6 91.4 0.48 280.6 94.9 0.49 0.686 0.9999 1973145 ChemDiv1_006084 CCOc1cc(cc([N+](=O)[O-])c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E13 compound treatment 280.8 94.6 0.49 275.8 90.1 0.47 0.6801 0.9997 1973146 ChemDiv1_006085 Cc1nc2ccccc2c(=O)n1OC(=O)/C=C/c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E14 compound treatment 284.0 97.8 0.51 285.7 100.0 0.52 0.7283 1.0 1428416 ChemDiv1_006086 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E15 compound treatment 274.8 88.6 0.46 279.1 93.4 0.49 0.6701 0.9997 1973147 ChemDiv1_006087 CCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E16 compound treatment 276.6 90.4 0.47 277.0 91.3 0.47 0.669 1.0 1461344 ChemDiv1_006088 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E17 compound treatment 275.1 88.9 0.46 277.4 91.7 0.48 0.665 0.9999 1230233 ChemDiv1_006089 CC(C)(C)C1CCc2c(C1)sc3[nH]c(=S)[nH]c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E18 compound treatment 277.4 91.2 0.48 275.0 89.3 0.46 0.6646 0.9999 1250418 ChemDiv1_006090 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E19 compound treatment 278.3 92.1 0.48 278.1 92.4 0.48 0.6794 1.0 1973148 ChemDiv1_006091 CC1(C)Cc2c(CO1)sc3nc(SCC(=O)O)n(Cc4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E20 compound treatment 275.2 89.0 0.46 272.8 87.1 0.45 0.6484 0.9999 1950556 ChemDiv1_006092 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(C)c(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E21 compound treatment 280.5 94.3 0.49 276.0 90.3 0.47 0.6797 0.9997 1414682 ChemDiv1_006093 CC(C)Cn1c(=O)c2c3CC(C)(C)OCc3sc2[nH]c1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E22 compound treatment 278.1 91.9 0.48 279.8 94.1 0.49 0.6849 1.0 1266337 ChemDiv1_006094 CC1CCCN(C1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E23 mock treatment 277.7 91.5 0.48 277.7 92.0 0.48 0.6757 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 E24 mock treatment 76.6 -110.0 -0.57 81.4 -104.0 -0.54 -0.7876 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F01 compound treatment 280.8 94.6 0.49 287.3 102.0 0.53 0.7224 0.9994 1973149 ChemDiv1_006095 COc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3Br)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F02 compound treatment 284.8 98.6 0.51 286.1 100.0 0.52 0.7327 1.0 1973150 ChemDiv1_006096 COc1ccc(Cl)cc1N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F03 compound treatment 281.7 95.5 0.5 283.6 97.9 0.51 0.7121 0.9999 1973151 ChemDiv1_006097 C/C(=C\1/C(=O)N(N=C1CSc2ccc(C)cc2)c3nc4ccccc4s3)/NCc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F04 compound treatment 282.3 96.1 0.5 281.7 96.0 0.5 0.7073 1.0 1229590 ChemDiv1_006098 Cc1ccc(cc1NC(=O)c2ccc3OCCOc3c2)c4nc5cc(Cl)cc(Cl)c5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F05 compound treatment 277.6 91.4 0.48 283.2 97.5 0.51 0.6955 0.9995 1925029 ChemDiv1_006099 COc1cccc(c1)C(=O)N2C(C)CC(N(C(=O)C(F)(F)F)c3ccccc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F06 compound treatment 282.2 96.0 0.5 283.2 97.5 0.51 0.7125 1.0 1450429 ChemDiv1_006100 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F07 compound treatment 277.3 91.1 0.48 277.2 91.5 0.48 0.6724 1.0 1234384 ChemDiv1_006101 Cc1ccc(cc1)C2N(C(=O)CCC(=O)O)c3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F08 compound treatment 279.8 93.6 0.49 281.2 95.5 0.5 0.6963 1.0 1168164 ChemDiv1_006102 Cc1nc2sc3CCCCc3c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F09 compound treatment 283.7 97.5 0.51 281.1 95.4 0.5 0.7103 0.9999 1973152 ChemDiv1_006103 CC/1=NN(C(=O)\C1=C\NCc2ccc3OCOc3c2)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F10 compound treatment 280.5 94.3 0.49 280.5 94.8 0.49 0.6963 1.0 1973153 ChemDiv1_006104 Clc1ccc(Oc2ccc(NC(=O)Cn3c4ccccc4c(=O)c5ccccc35)cc2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F11 compound treatment 336.7 151.0 0.79 326.2 140.0 0.73 1.0716 0.9993 1973154 ChemDiv1_006105 CC(C)CN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F12 compound treatment 279.3 93.1 0.49 280.6 94.9 0.49 0.6922 1.0 1532399 ChemDiv1_006106 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F13 compound treatment 297.7 112.0 0.58 299.5 114.0 0.59 0.8296 1.0 1973155 ChemDiv1_006107 COCCCN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(C)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F14 compound treatment 275.3 89.1 0.46 276.9 91.2 0.47 0.6639 1.0 1344065 ChemDiv1_006108 COc1ccc(O)c(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F15 compound treatment 279.0 92.8 0.48 276.4 90.7 0.47 0.6757 0.9999 1973156 ChemDiv1_006109 CCCCOc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F16 compound treatment 276.7 90.5 0.47 276.5 90.8 0.47 0.6676 1.0 1379296 ChemDiv1_006110 CCOC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F17 compound treatment 278.5 92.3 0.48 277.7 92.0 0.48 0.6786 1.0 1500053 ChemDiv1_006111 CC(=O)Nc1ccc(Oc2nnc(c3ccc(Cl)cc3)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F18 compound treatment 278.9 92.7 0.48 278.9 93.2 0.48 0.6845 1.0 1973157 ChemDiv1_006112 CCOC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F19 compound treatment 276.2 90.0 0.47 283.6 97.9 0.51 0.6918 0.9992 1397533 ChemDiv1_006113 COC(=O)c1ccc(cc1)c2nnc(Nc3ccc(Cl)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F20 compound treatment 271.8 85.6 0.45 270.2 84.5 0.44 0.6263 1.0 1924652 ChemDiv1_006114 Cc1csc(n1)c2cc3ccc(OC/C=C/c4ccccc4)cc3oc2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F21 compound treatment 280.1 93.9 0.49 274.5 88.8 0.46 0.6728 0.9996 1424194 ChemDiv1_006115 COC(=O)c1ccc(Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F22 compound treatment 277.0 90.8 0.47 276.0 90.3 0.47 0.6668 1.0 1372136 ChemDiv1_006116 CCOC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OCc3ccccc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F23 mock treatment 276.9 90.7 0.47 280.6 94.9 0.49 0.6834 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 F24 mock treatment 77.8 -108.0 -0.57 75.2 -111.0 -0.57 -0.806 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G01 compound treatment 286.4 100.0 0.52 281.5 95.8 0.5 0.7217 0.9997 1591908 ChemDiv1_006117 CCC(C)C(=O)N1C(C)CC(N(C(=O)c2cccc(Cl)c2)c3ccccc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G02 compound treatment 290.8 105.0 0.55 284.8 99.1 0.52 0.7501 0.9996 1620057 ChemDiv1_006118 O=c1n(C2CCCCC2)c(=S)[nH]c3sc4CCCc4c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G03 compound treatment 278.9 92.7 0.48 284.5 98.8 0.51 0.7051 0.9995 1446863 ChemDiv1_006119 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3c(C)cc(C)cc3C)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G04 compound treatment 282.7 96.5 0.5 285.2 99.5 0.52 0.7217 0.9999 1351010 ChemDiv1_006120 CCOC(=O)CSc1nc2sc3CN(C)CCc3c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G05 compound treatment 289.7 104.0 0.54 290.8 105.0 0.55 0.7681 1.0 1385731 ChemDiv1_006121 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(C)cc3C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G06 compound treatment 282.4 96.2 0.5 280.0 94.3 0.49 0.7015 0.9999 1565498 ChemDiv1_006122 CCOC(=O)c1c(CSc2ccccc2)n(Cc3ccccc3)c4cc(Br)c(O)c(CN(C)C)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G07 compound treatment 281.9 95.7 0.5 280.6 94.9 0.49 0.7018 1.0 1402059 ChemDiv1_006123 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3ccc(C)cc3C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G08 compound treatment 285.6 99.4 0.52 291.0 105.0 0.55 0.7537 0.9996 1342061 ChemDiv1_006124 Oc1ccccc1C(C#N)N2N=C(CC2c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G09 compound treatment 275.0 88.8 0.46 282.8 97.1 0.5 0.6845 0.9991 1124980 ChemDiv1_006125 CCOC(=O)Cn1c(Sc2nc3n(C)c(=O)n(C)c(=O)c3n2C)nc4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G10 compound treatment 278.7 92.5 0.48 279.3 93.6 0.49 0.6852 1.0 1973158 ChemDiv1_006126 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(Br)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G11 compound treatment 273.7 87.5 0.46 271.1 85.4 0.44 0.6367 0.9999 1973159 ChemDiv1_006127 COc1ccccc1OCCn2cc(C=C3C(=O)NC(=S)NC3=O)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G12 compound treatment 276.8 90.6 0.47 280.2 94.5 0.49 0.6815 0.9998 1950533 ChemDiv1_006128 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G13 compound treatment 327.0 141.0 0.73 299.0 113.0 0.59 0.9358 0.994 1973160 ChemDiv1_006129 Oc1cccc(c1)n2c(/C=C/c3cc(Br)ccc3O)nc4ccccc4c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G14 compound treatment 276.5 90.3 0.47 277.0 91.3 0.47 0.6687 1.0 1425310 ChemDiv1_006130 COc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G15 compound treatment 286.0 99.8 0.52 282.0 96.3 0.5 0.7221 0.9998 1577022 ChemDiv1_006131 NC(=O)CSc1nc2sc3CCCCCc3c2c(=O)n1C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G16 compound treatment 278.7 92.5 0.48 277.9 92.2 0.48 0.6801 1.0 1426969 ChemDiv1_006132 COc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G17 compound treatment 281.1 94.9 0.5 281.2 95.5 0.5 0.7011 1.0 1973161 ChemDiv1_006133 COc1ccc(cc1)n2c(SC)nc3sc4COC(C)(C)Cc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G18 compound treatment 277.8 91.6 0.48 280.5 94.8 0.49 0.6863 0.9999 1687208 ChemDiv1_006134 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G19 compound treatment 277.7 91.5 0.48 278.9 93.2 0.48 0.6801 1.0 1973162 ChemDiv1_006135 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G20 compound treatment 278.4 92.2 0.48 274.7 89.0 0.46 0.6672 0.9998 1531762 ChemDiv1_006136 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G21 compound treatment 275.8 89.6 0.47 281.3 95.6 0.5 0.6819 0.9995 1973163 ChemDiv1_006137 CC(=C)Cn1c(SCC(=C)Br)nc2sc3COC(C)(C)Cc3c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G22 compound treatment 275.3 89.1 0.46 280.9 95.2 0.49 0.6786 0.9995 1708729 ChemDiv1_006138 COc1ccc(Nc2nc3nonc3nc2Nc4ccc(OC)cc4OC)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G23 mock treatment 280.8 94.6 0.49 281.6 95.9 0.5 0.7014 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 G24 mock treatment 81.1 -105.0 -0.55 71.0 -115.0 -0.6 -0.8093 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H01 compound treatment 281.3 95.1 0.5 288.4 103.0 0.53 0.7283 0.9993 1156675 ChemDiv1_006139 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc3nc(oc3c2)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H02 compound treatment 286.5 100.0 0.52 282.4 96.7 0.5 0.7254 0.9998 1973164 ChemDiv1_006140 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H03 compound treatment 281.6 95.4 0.5 283.2 97.5 0.51 0.7103 1.0 1973165 ChemDiv1_006141 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCCCN3CCOCC3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H04 compound treatment 280.7 94.5 0.49 282.6 96.9 0.5 0.7047 0.9999 1590418 ChemDiv1_006142 O=C(Cn1c(SCc2ccccc2)nc3ccccc13)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H05 compound treatment 285.2 99.0 0.52 280.5 94.8 0.49 0.7136 0.9997 1475097 ChemDiv1_006143 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4cccc(OC)c4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H06 compound treatment 282.8 96.6 0.5 285.6 99.9 0.52 0.7235 0.9999 1686613 ChemDiv1_006144 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OC(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H07 compound treatment 277.4 91.2 0.48 279.0 93.3 0.48 0.6793 1.0 1690394 ChemDiv1_006145 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(C)cc5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H08 compound treatment 284.0 97.8 0.51 283.7 98.0 0.51 0.721 1.0 1973166 ChemDiv1_006146 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H09 compound treatment 277.4 91.2 0.48 279.7 94.0 0.49 0.6819 0.9999 1973167 ChemDiv1_006147 CC/1=NN(C(=O)\C1=C\NCCc2ccc(cc2)S(=O)(=O)N)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H10 compound treatment 281.8 95.6 0.5 279.6 93.9 0.49 0.6978 0.9999 1973168 ChemDiv1_006148 Cc1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)ccc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H11 compound treatment 302.9 117.0 0.61 303.8 118.0 0.61 0.8646 1.0 1973169 ChemDiv1_006149 COCCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H12 compound treatment 277.3 91.1 0.48 279.1 93.4 0.49 0.6793 0.9999 1973170 ChemDiv1_006150 O=C(Cn1c2ccccc2c(=O)c3ccccc13)NC(c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H13 compound treatment 295.7 110.0 0.57 297.5 112.0 0.58 0.8148 1.0 1973171 ChemDiv1_006151 CN1CCN(CC1)c2nc3c(C)cccn3c(=O)c2/C=C/4\SC(=S)N(CC5CCCO5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H14 compound treatment 278.2 92.0 0.48 281.6 95.9 0.5 0.6918 0.9998 1276069 ChemDiv1_006152 CCn1c2ccccc2c3cc(ccc13)C4C(=C(N)OC5=C4C(=O)CC(C)(C)C5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H15 compound treatment 275.6 89.4 0.47 278.5 92.8 0.48 0.6709 0.9999 1973172 ChemDiv1_006153 CCCCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H16 compound treatment 273.7 87.5 0.46 272.4 86.7 0.45 0.6414 1.0 1438869 ChemDiv1_006154 CC(C)OC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H17 compound treatment 277.9 91.7 0.48 279.5 93.8 0.49 0.683 1.0 1437662 ChemDiv1_006155 COc1ccc(cc1)c2nnc(Oc3ccc(NC(=O)C)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H18 compound treatment 276.6 90.4 0.47 277.3 91.6 0.48 0.6701 1.0 1973173 ChemDiv1_006156 CC(C)OC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H19 compound treatment 277.9 91.7 0.48 279.8 94.1 0.49 0.6841 0.9999 1141217 ChemDiv1_006157 Cc1nc2cc(Nc3nnc(C)c4ccccc34)ccc2n1Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H20 compound treatment 278.2 92.0 0.48 277.4 91.7 0.48 0.6764 1.0 1206829 ChemDiv1_006158 CCOC(=O)c1c(oc2cc(Br)c(OC(=O)c3ccco3)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H21 compound treatment 281.8 95.6 0.5 279.2 93.5 0.49 0.6963 0.9999 1230084 ChemDiv1_006159 Cc1ccc(Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H22 compound treatment 277.1 90.9 0.47 279.5 93.8 0.49 0.6801 0.9999 1924787 ChemDiv1_006160 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3ccc(cc3)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H23 mock treatment 284.6 98.4 0.51 277.0 91.3 0.47 0.6985 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 H24 mock treatment 81.3 -105.0 -0.55 76.8 -109.0 -0.57 -0.7872 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I01 compound treatment 285.3 99.1 0.52 286.1 100.0 0.52 0.7346 1.0 1973174 ChemDiv1_006161 CCOc1ccc2N(C(=O)c3sc4ccccc4c3Cl)C(C)(C)C(=S)C(=C5SC(=C(S5)C(=O)OC)C(=O)OC)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I02 compound treatment 281.8 95.6 0.5 287.6 102.0 0.53 0.7272 0.9995 1397245 ChemDiv1_006162 CCC1(C)Cc2c(CO1)sc3[nH]c(=S)n(CC(=C)C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I03 compound treatment 283.7 97.5 0.51 282.8 97.1 0.5 0.7165 1.0 1973175 ChemDiv1_006163 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I04 compound treatment 278.1 91.9 0.48 278.0 92.3 0.48 0.6782 1.0 1973176 ChemDiv1_006164 CSc1nc(NC(C)(C)C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I05 compound treatment 291.1 105.0 0.55 289.7 104.0 0.54 0.7692 1.0 1214687 ChemDiv1_006165 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3c(C)cc(C)cc3C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I06 compound treatment 282.7 96.5 0.5 281.9 96.2 0.5 0.7095 1.0 1197848 ChemDiv1_006166 CCOC(=O)c1c(CN(CC)CC)n(C)c2c1cc(OC(=O)C)c3n(nc(c4ccccc4)c32)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I07 compound treatment 282.6 96.4 0.5 283.5 97.8 0.51 0.7151 1.0 1403348 ChemDiv1_006167 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(C)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I08 compound treatment 282.3 96.1 0.5 284.4 98.7 0.51 0.7173 0.9999 1585010 ChemDiv1_006168 COc1ccc(cc1OC)C(C#N)N2N=C(CC2c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I09 compound treatment 281.0 94.8 0.49 282.4 96.7 0.5 0.7051 1.0 1612433 ChemDiv1_006169 Cc1ccn2c(NC(=O)c3cccc(Br)c3)c(nc2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I10 compound treatment 278.1 91.9 0.48 282.7 97.0 0.5 0.6955 0.9997 1580047 ChemDiv1_006170 Brc1ccccc1Nc2ncnc3n(Cc4ccccc4)ncc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I11 compound treatment 273.5 87.3 0.46 272.9 87.2 0.45 0.6425 1.0 1927342 ChemDiv1_006171 CCc1cc(C)cc(OCCn2cc(C=C3C(=O)NC(=S)NC3=O)c4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I12 compound treatment 277.6 91.4 0.48 280.0 94.3 0.49 0.6838 0.9999 1485105 ChemDiv1_006172 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I13 compound treatment 279.0 92.8 0.48 280.9 95.2 0.49 0.6922 0.9999 1678216 ChemDiv1_006173 CC(C)(O)C#Cc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I14 compound treatment 276.0 89.8 0.47 276.6 90.9 0.47 0.6654 1.0 1176339 ChemDiv1_006174 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OC5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I15 compound treatment 276.3 90.1 0.47 279.6 93.9 0.49 0.6775 0.9998 1236932 ChemDiv1_006175 CCSc1nc(NC(=O)N)c2c3CCC(Cc3sc2n1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I16 compound treatment 278.0 91.8 0.48 275.0 89.3 0.46 0.6668 0.9999 1973177 ChemDiv1_006176 CCOc1cc(cc([N+](=O)[O-])c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I17 compound treatment 282.1 95.9 0.5 280.2 94.5 0.49 0.7011 1.0 1376789 ChemDiv1_006177 NC(=O)CSc1nc2sc3CCCCCc3c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I18 compound treatment 277.2 91.0 0.47 276.2 90.5 0.47 0.6683 1.0 1635665 ChemDiv1_006178 CCOc1cc(ccc1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I19 compound treatment 278.3 92.1 0.48 278.4 92.7 0.48 0.6805 1.0 1973178 ChemDiv1_006179 CCCCCOC(=O)CSc1nc(N)c2c3CC(C)(C)OCc3sc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I20 compound treatment 275.3 89.1 0.46 271.7 86.0 0.45 0.6448 0.9998 1481422 ChemDiv1_006180 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I21 compound treatment 275.2 89.0 0.46 277.6 91.9 0.48 0.6661 0.9999 1345533 ChemDiv1_006181 COc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I22 compound treatment 277.8 91.6 0.48 275.4 89.7 0.47 0.6676 0.9999 1423957 ChemDiv1_006182 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2cccc(NC(=O)c3cccc(c3)S(=O)(=O)N(CC)CC)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I23 mock treatment 279.1 92.9 0.48 275.0 89.3 0.46 0.6709 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 I24 mock treatment 77.6 -109.0 -0.57 86.8 -98.9 -0.51 -0.7641 -0.9988 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J01 compound treatment 286.1 99.9 0.52 285.9 100.0 0.52 0.7368 1.0 1533251 ChemDiv1_006183 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccc(NC(=O)c5ccc(OC(=O)C)cc5)cc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J02 compound treatment 282.2 96.0 0.5 284.9 99.2 0.52 0.7187 0.9999 1364665 ChemDiv1_006184 COc1ccccc1N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J03 compound treatment 282.0 95.8 0.5 281.2 95.5 0.5 0.7044 1.0 1973179 ChemDiv1_006185 COc1ccc(CN/C=C\2/C(=O)N(N=C2CSc3ccc(C)cc3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J04 compound treatment 280.5 94.3 0.49 282.1 96.4 0.5 0.7022 1.0 1973180 ChemDiv1_006186 OC(=O)C1CCN(CC1)S(=O)(=O)c2cc(ccc2Br)C(=O)Nc3cccc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J05 compound treatment 284.2 98.0 0.51 279.2 93.5 0.49 0.7052 0.9997 1130618 ChemDiv1_006187 CCOc1ccc2N(C(=O)CSc3nnc(N)s3)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J06 compound treatment 288.3 102.0 0.53 284.2 98.5 0.51 0.7387 0.9998 1269364 ChemDiv1_006188 COc1ccc(cc1)C(=O)Oc2cc(C=c3sc4nc5ccccc5n4c3=O)ccc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J07 compound treatment 281.9 95.7 0.5 285.0 99.3 0.52 0.718 0.9999 1973181 ChemDiv1_006189 CCC(=O)N1C(C2=C(CC(CC2=O)c3cc(OC)c(OC)c(OC)c3)Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J08 compound treatment 283.2 97.0 0.51 283.1 97.4 0.51 0.7158 1.0 1973182 ChemDiv1_006190 Fc1ccc(cc1)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J09 compound treatment 279.0 92.8 0.48 283.4 97.7 0.51 0.7014 0.9997 1973183 ChemDiv1_006191 CCCC/1=NN(C(=O)\C1=C\NCc2ccc(OC)cc2)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J10 compound treatment 281.8 95.6 0.5 282.5 96.8 0.5 0.7084 1.0 1973184 ChemDiv1_006192 COc1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J11 compound treatment 265.4 79.2 0.41 280.0 94.3 0.49 0.6388 0.9964 1973185 ChemDiv1_006193 CC(C)CN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CC(C)OC(C)C4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J12 compound treatment 277.8 91.6 0.48 281.2 95.5 0.5 0.6889 0.9998 1973186 ChemDiv1_006194 CCn1c2ccccc2c3cc(NC(=O)Cn4c5ccccc5c(=O)c6ccccc46)ccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J13 compound treatment 280.2 94.0 0.49 278.7 93.0 0.48 0.6886 1.0 1973187 ChemDiv1_006195 CCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J14 compound treatment 279.4 93.2 0.49 281.3 95.6 0.5 0.6952 0.9999 1700689 ChemDiv1_006196 COC(=O)C1=C(N)OC2=C(C1c3cccc(C)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J15 compound treatment 280.7 94.5 0.49 280.5 94.8 0.49 0.697 1.0 1420065 ChemDiv1_006197 CCN(CC)CCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J16 compound treatment 277.2 91.0 0.47 280.8 95.1 0.49 0.6852 0.9998 1924681 ChemDiv1_006198 COCCOC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J17 compound treatment 283.7 97.5 0.51 279.1 93.4 0.49 0.7029 0.9997 1536923 ChemDiv1_006199 CC(=O)Nc1cccc(Oc2nnc(c3ccc(C)cc3)c4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J18 compound treatment 279.8 93.6 0.49 273.7 88.0 0.46 0.6687 0.9995 1973188 ChemDiv1_006200 COCCOC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J19 compound treatment 275.5 89.3 0.47 278.0 92.3 0.48 0.6687 0.9999 1729995 ChemDiv1_006201 Cc1nc2cc(Nc3nnc(c4ccccc4)c5ccccc35)ccc2n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J20 compound treatment 281.0 94.8 0.49 276.0 90.3 0.47 0.6816 0.9997 1393926 ChemDiv1_006202 CCOC(=O)COc1cc2c(C(=O)OCC)c(oc2cc1Br)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J21 compound treatment 277.9 91.7 0.48 278.7 93.0 0.48 0.6801 1.0 1407870 ChemDiv1_006203 Fc1cccc(c1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J22 compound treatment 277.0 90.8 0.47 275.9 90.2 0.47 0.6665 1.0 1516219 ChemDiv1_006204 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OCc3ccccc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J23 mock treatment 273.8 87.6 0.46 279.6 93.9 0.49 0.6683 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 J24 mock treatment 77.1 -109.0 -0.57 88.4 -97.3 -0.51 -0.7601 -0.9983 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K01 compound treatment 284.3 98.1 0.51 286.6 101.0 0.52 0.7327 0.9999 1973189 ChemDiv1_006205 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3sc4ccccc4c3Cl)c5c(C)cccc25)S1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K02 compound treatment 283.0 96.8 0.5 281.7 96.0 0.5 0.7099 1.0 1973190 ChemDiv1_006206 CCOC(=O)CSc1nc2sc3COC(C)(CC)Cc3c2c(=O)n1Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K03 compound treatment 278.9 92.7 0.48 279.1 93.4 0.49 0.6852 1.0 1583069 ChemDiv1_006207 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(Br)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K04 compound treatment 279.8 93.6 0.49 280.4 94.7 0.49 0.6933 1.0 1154521 ChemDiv1_006208 Cc1nc2scc(c3ccccc3)c2c(=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K05 compound treatment 279.3 93.1 0.49 279.7 94.0 0.49 0.6889 1.0 1973191 ChemDiv1_006209 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cccc(c3)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K06 compound treatment 281.7 95.5 0.5 279.5 93.8 0.49 0.697 0.9999 1973192 ChemDiv1_006210 CCOC(=O)c1c(C)n(Cc2ccccc2)c3c1cc(O)c4n(nc(c5ccccc5)c43)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K07 compound treatment 281.8 95.6 0.5 279.6 93.9 0.49 0.6978 0.9999 1268068 ChemDiv1_006211 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(Cl)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K08 compound treatment 279.8 93.6 0.49 281.1 95.4 0.5 0.6959 1.0 1925318 ChemDiv1_006212 Fc1c(F)c(c(F)c(F)c1N2C(=O)c3ccccc3S2(=O)=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K09 compound treatment 276.9 90.7 0.47 280.9 95.2 0.49 0.6845 0.9997 1722550 ChemDiv1_006213 CCCCC(=O)Nc1c(nc2cc(C)ccn12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K10 compound treatment 278.2 92.0 0.48 277.6 91.9 0.48 0.6771 1.0 1626695 ChemDiv1_006214 Brc1ccc(Nc2ncnc3n(Cc4ccccc4)ncc23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K11 compound treatment 284.7 98.5 0.51 283.1 97.4 0.51 0.7213 1.0 1613089 ChemDiv1_006215 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OC(=O)c5ccccc5F)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K12 compound treatment 277.0 90.8 0.47 275.6 89.9 0.47 0.6654 1.0 1695998 ChemDiv1_006216 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(cc5)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K13 compound treatment 280.1 93.9 0.49 280.2 94.5 0.49 0.6937 1.0 1973193 ChemDiv1_006217 CCOC(=O)CSc1nc(N)c2c3CCC(Cc3sc2n1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K14 compound treatment 279.2 93.0 0.49 280.1 94.4 0.49 0.69 1.0 1668953 ChemDiv1_006218 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6c(Cl)cc(Cl)cc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K15 compound treatment 280.2 94.0 0.49 280.2 94.5 0.49 0.6941 1.0 1530611 ChemDiv1_006219 COc1ccc(cc1)n2c(SCC(=O)O)nc3sc4CCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K16 compound treatment 277.8 91.6 0.48 277.8 92.1 0.48 0.6764 1.0 1950497 ChemDiv1_006220 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc(O)c(c4)[N+](=O)[O-])C(=O)OCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K17 compound treatment 275.1 88.9 0.46 277.0 91.3 0.47 0.6635 0.9999 1973194 ChemDiv1_006221 CC(C)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K18 compound treatment 275.0 88.8 0.46 277.2 91.5 0.48 0.6639 0.9999 1950426 ChemDiv1_006222 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K19 compound treatment 280.3 94.1 0.49 280.2 94.5 0.49 0.6944 1.0 1362292 ChemDiv1_006223 CC(=C)Cn1c(SCC(=O)N)nc2sc3COC(C)(C)Cc3c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K20 compound treatment 273.7 87.5 0.46 278.4 92.7 0.48 0.6635 0.9996 1135734 ChemDiv1_006224 CCOc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K21 compound treatment 278.4 92.2 0.48 283.7 98.0 0.51 0.7003 0.9996 1973195 ChemDiv1_006225 CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K22 compound treatment 274.4 88.2 0.46 272.1 86.4 0.45 0.6429 0.9999 1643471 ChemDiv1_006226 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2nnc(Cc3cccc(C)c3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K23 mock treatment 280.7 94.5 0.49 282.8 97.1 0.5 0.7055 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 K24 mock treatment 62.8 -123.0 -0.64 79.3 -106.0 -0.55 -0.8463 -0.9971 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L01 compound treatment 281.7 95.5 0.5 286.3 101.0 0.52 0.722 0.9997 1615447 ChemDiv1_006227 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4cc(NC(=O)c5ccc(OC(=O)C)cc5)ccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L02 compound treatment 283.9 97.7 0.51 280.3 94.6 0.49 0.7081 0.9998 1973196 ChemDiv1_006228 FC(F)(F)c1cc(ccc1Cl)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L03 compound treatment 278.4 92.2 0.48 279.3 93.6 0.49 0.6841 1.0 1973197 ChemDiv1_006229 CCCCCCCCN/C=C\1/Sc2ccc(OCC)cc2C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L04 compound treatment 282.4 96.2 0.5 285.1 99.4 0.52 0.7202 0.9999 1973198 ChemDiv1_006230 Cc1ccc(cc1NS(=O)(=O)c2cc(C(=O)Nc3ccccc3)c(Cl)cc2Cl)S(=O)(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L05 compound treatment 283.1 96.9 0.51 285.2 99.5 0.52 0.7232 0.9999 1131778 ChemDiv1_006231 O=C(CCN1C(=O)c2ccccc2C1=O)N3c4ccccc4Sc5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L06 compound treatment 282.2 96.0 0.5 281.2 95.5 0.5 0.7051 1.0 1973199 ChemDiv1_006232 [O-][N+](=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc3nc(NC(=O)C4CCCCC4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L07 compound treatment 283.2 97.0 0.51 279.7 94.0 0.49 0.7033 0.9998 1973200 ChemDiv1_006233 COc1ccc(cc1)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4cccc(Br)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L08 compound treatment 284.4 98.2 0.51 282.4 96.7 0.5 0.7177 1.0 1973201 ChemDiv1_006234 O=c1oc(/C=C/c2ccccc2)nc3sc4CCCCc4c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L09 compound treatment 291.2 105.0 0.55 285.1 99.4 0.52 0.7527 0.9996 1973202 ChemDiv1_006235 CC(C)N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(Cc5ccccc5)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L10 compound treatment 282.6 96.4 0.5 279.3 93.6 0.49 0.6996 0.9999 1973203 ChemDiv1_006236 COc1cc(OC)c(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L11 compound treatment 283.5 97.3 0.51 276.9 91.2 0.47 0.6941 0.9994 1973204 ChemDiv1_006237 CC(N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCCC4)/SC1=S)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L12 compound treatment 278.5 92.3 0.48 279.5 93.8 0.49 0.6852 1.0 1973205 ChemDiv1_006238 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L13 compound treatment 278.1 91.9 0.48 279.9 94.2 0.49 0.6852 0.9999 1637527 ChemDiv1_006239 CCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L14 compound treatment 274.9 88.7 0.46 278.5 92.8 0.48 0.6683 0.9998 1973206 ChemDiv1_006240 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(F)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L15 compound treatment 273.8 87.6 0.46 277.8 92.1 0.48 0.6616 0.9997 1376814 ChemDiv1_006241 CCN(CC)CCOc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L16 compound treatment 121.8 -64.4 -0.34 133.7 -52.0 -0.27 -0.4287 -0.9942 1488976 ChemDiv1_006242 Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1CN5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L17 compound treatment 279.5 93.3 0.49 279.0 93.3 0.48 0.6871 1.0 1151091 ChemDiv1_006243 CC(=O)Nc1cccc(Oc2nnc(c3ccc(Cl)cc3)c4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L18 compound treatment 281.1 94.9 0.5 277.1 91.4 0.48 0.686 0.9998 1973207 ChemDiv1_006244 COCCOC(=O)c1c(C)oc2ccc(OCc3ccc(cc3)c4cnc(o4)c5ccccc5)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L19 compound treatment 279.9 93.7 0.49 281.8 96.1 0.5 0.6989 0.9999 1208565 ChemDiv1_006245 COc1ccc(cc1)c2nnc(Nc3ccc4n(C)cnc4c3)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L20 compound treatment 279.1 92.9 0.48 280.3 94.6 0.49 0.6904 1.0 1924846 ChemDiv1_006246 COC(=O)c1c(C)oc2cc(Br)c(OC(=O)c3ccc(cc3)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L21 compound treatment 278.0 91.8 0.48 276.3 90.6 0.47 0.6716 1.0 1138961 ChemDiv1_006247 Fc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L22 compound treatment 275.3 89.1 0.46 280.7 95.0 0.49 0.6778 0.9995 1925014 ChemDiv1_006248 COC(=O)c1c(C)oc2cc(Br)c(OCc3ccc(cc3)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L23 mock treatment 279.9 93.7 0.49 278.7 93.0 0.48 0.6875 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 L24 mock treatment 79.0 -107.0 -0.56 76.9 -109.0 -0.57 -0.7953 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M01 compound treatment 283.6 97.4 0.51 284.8 99.1 0.52 0.7235 1.0 1973208 ChemDiv1_006249 CC1CC(N(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc4)c5ccccc5N1C(=O)CN6C(=O)c7ccccc7C6=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M02 compound treatment 282.2 96.0 0.5 283.3 97.6 0.51 0.7128 1.0 1973209 ChemDiv1_006250 CCC1(C)Cc2c(CO1)sc3nc(SCC(=O)O)n(c4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M03 compound treatment 281.0 94.8 0.49 277.2 91.5 0.48 0.686 0.9998 1720942 ChemDiv1_006251 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3cc(Cl)ccc3Cl)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M04 compound treatment 279.6 93.4 0.49 280.5 94.8 0.49 0.693 1.0 1973210 ChemDiv1_006252 CCCN1C(=O)C(CC(=O)C)(OC(=O)C)c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M05 compound treatment 284.2 98.0 0.51 282.2 96.5 0.5 0.7162 1.0 1250181 ChemDiv1_006253 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M06 compound treatment 275.4 89.2 0.47 281.9 96.2 0.5 0.6826 0.9994 1464524 ChemDiv1_006254 CCOC(=O)c1c(C)[nH]c2c1cc(O)c3n(nc(c4ccccc4)c23)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M07 compound treatment 282.7 96.5 0.5 278.9 93.2 0.48 0.6985 0.9998 1485619 ChemDiv1_006255 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3ccc(CC)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M08 compound treatment 279.6 93.4 0.49 284.3 98.6 0.51 0.7069 0.9997 1973211 ChemDiv1_006256 FC(F)(F)c1cc(nc(SCC(=O)N2CCOCC2)c1C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M09 compound treatment 281.5 95.3 0.5 281.2 95.5 0.5 0.7025 1.0 1333769 ChemDiv1_006257 Brc1ccccc1C(=O)Nc2c(nc3ccccn23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M10 compound treatment 276.3 90.1 0.47 278.6 92.9 0.48 0.6738 0.9999 1614418 ChemDiv1_006258 O=c1oc(nc2sc3CCCCCc3c12)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M11 compound treatment 280.0 93.8 0.49 278.2 92.5 0.48 0.686 1.0 1443565 ChemDiv1_006259 CCCCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M12 compound treatment 275.9 89.7 0.47 282.0 96.3 0.5 0.6848 0.9994 1466674 ChemDiv1_006260 Cc1ccc2occ(C3Nc4cc(C)c(C)cc4NC5=C3C(=O)CC(C)(C)C5)c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M13 compound treatment 283.0 96.8 0.5 278.0 92.3 0.48 0.6963 0.9997 1691214 ChemDiv1_006261 COC(=O)CSc1nc(N)c2c3CCC(Cc3sc2n1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M14 compound treatment 274.9 88.7 0.46 266.7 81.0 0.42 0.6249 0.9989 1950435 ChemDiv1_006262 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(ccc5Cl)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M15 compound treatment 275.6 89.4 0.47 279.4 93.7 0.49 0.6742 0.9998 1973212 ChemDiv1_006263 COC(=O)CSc1nnc2n(c3ccc(OC)cc3)c(=O)c4c5CCCCCc5sc4n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M16 compound treatment 275.4 89.2 0.47 275.5 89.8 0.47 0.6591 1.0 1973213 ChemDiv1_006264 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)OCCOc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M17 compound treatment 276.3 90.1 0.47 279.0 93.3 0.48 0.6753 0.9999 1973214 ChemDiv1_006265 CCCCCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M18 compound treatment 275.3 89.1 0.46 274.0 88.3 0.46 0.6532 1.0 1950470 ChemDiv1_006266 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(c5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M19 compound treatment 276.9 90.7 0.47 277.3 91.6 0.48 0.6712 1.0 1973215 ChemDiv1_006267 CCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M20 compound treatment 278.3 92.1 0.48 279.3 93.6 0.49 0.6838 1.0 1973216 ChemDiv1_006268 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC)c(OC)c5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M21 compound treatment 280.3 94.1 0.49 275.4 89.7 0.47 0.6768 0.9997 1933595 ChemDiv1_006269 CN1CCc2c(C1)sc3[nH]c(=S)n(CCc4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M22 compound treatment 281.2 95.0 0.5 277.0 91.3 0.47 0.686 0.9998 1680463 ChemDiv1_006270 Clc1ccc(OCc2nnc(NC(=O)c3cccc(c3)S(=O)(=O)N4CCOCC4)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M23 mock treatment 281.2 95.0 0.5 277.7 92.0 0.48 0.6886 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 M24 mock treatment 193.0 6.81 0.04 183.7 -2.01 -0.01 0.0177 0.4792 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N01 compound treatment 283.0 96.8 0.5 284.5 98.8 0.51 0.7202 1.0 1169903 ChemDiv1_006271 COc1ccccc1NC(=O)CSc2nc3CCCCc3cc2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N02 compound treatment 285.5 99.3 0.52 277.6 91.9 0.48 0.7041 0.9992 1679313 ChemDiv1_006272 CCOc1ccccc1N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N03 compound treatment 285.3 99.1 0.52 282.0 96.3 0.5 0.7195 0.9999 1973217 ChemDiv1_006273 CCOc1ccc2S/C(=C/NCCCOC)/C(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N04 compound treatment 286.5 100.0 0.52 284.3 98.6 0.51 0.7324 0.9999 1973218 ChemDiv1_006274 COc1ccc(/C=C/2\SC(=N)NC2=O)cc1OCc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N05 compound treatment 282.3 96.1 0.5 281.4 95.7 0.5 0.7062 1.0 1973219 ChemDiv1_006275 CC(N1C(=O)C2CCCCC2C1=O)C(=O)N3c4ccccc4C(C)(CC3(C)C)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N06 compound treatment 286.5 100.0 0.52 284.5 98.8 0.51 0.7331 1.0 1323093 ChemDiv1_006276 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)cc3)c(=O)n2C1c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N07 compound treatment 282.0 95.8 0.5 284.0 98.3 0.51 0.7147 0.9999 1660389 ChemDiv1_006277 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4ccccc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N08 compound treatment 277.1 90.9 0.47 281.8 96.1 0.5 0.6885 0.9997 1973220 ChemDiv1_006278 O=C(Cn1c2ccccc2c(=O)c3ccccc13)Nc4ccc(Oc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N09 compound treatment 284.0 97.8 0.51 288.7 103.0 0.54 0.7393 0.9997 1973221 ChemDiv1_006279 COCCCN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(Cc5ccccc5)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N10 compound treatment 276.4 90.2 0.47 278.9 93.2 0.48 0.6753 0.9999 1322065 ChemDiv1_006280 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N11 compound treatment 271.2 85.0 0.44 268.4 82.7 0.43 0.6175 0.9999 1973222 ChemDiv1_006281 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCc4ccccc4)C3=O)c(nc12)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N12 compound treatment 275.8 89.6 0.47 278.3 92.6 0.48 0.6709 0.9999 1973223 ChemDiv1_006282 COc1cc(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N13 compound treatment 277.0 90.8 0.47 280.7 95.0 0.49 0.6841 0.9998 1973224 ChemDiv1_006283 CCCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N14 compound treatment 121.6 -64.6 -0.34 101.3 -84.4 -0.44 -0.5485 -0.9915 1723325 ChemDiv1_006284 Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1CN5CCCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N15 compound treatment 279.4 93.2 0.49 275.6 89.9 0.47 0.6742 0.9998 1589686 ChemDiv1_006285 CCN(CC)CCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N16 compound treatment 276.8 90.6 0.47 275.5 89.8 0.47 0.6643 1.0 1924822 ChemDiv1_006286 COCCOC(=O)c1c(C)oc2ccc(OCc3c(F)c(F)c(F)c(F)c3F)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N17 compound treatment 274.4 88.2 0.46 276.9 91.2 0.47 0.6606 0.9999 1163825 ChemDiv1_006287 COc1ccc(cc1)c2nnc(Oc3cccc(NC(=O)C)c3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N18 compound treatment 277.4 91.2 0.48 276.0 90.3 0.47 0.6683 1.0 1925060 ChemDiv1_006288 COCCOC(=O)c1c(C)oc2ccc(OC(=O)c3sc4ccccc4c3Cl)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N19 compound treatment 277.8 91.6 0.48 277.4 91.7 0.48 0.6749 1.0 1403706 ChemDiv1_006289 CCOC(=O)Cc1nnc(Nc2ccc(C)cc2C)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N20 compound treatment 278.2 92.0 0.48 278.2 92.5 0.48 0.6793 1.0 1265136 ChemDiv1_006290 COC(=O)c1c(C)oc2cc(Br)c(OC(=O)c3ccc(Cl)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N21 compound treatment 274.8 88.6 0.46 271.2 85.5 0.44 0.6411 0.9998 1973225 ChemDiv1_006291 Cc1ccc(cc1)N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4sc5ccccc5c4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N22 compound treatment 276.5 90.3 0.47 279.6 93.9 0.49 0.6782 0.9998 1489880 ChemDiv1_006292 COC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OCc3ccccc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N23 mock treatment 276.6 90.4 0.47 278.3 92.6 0.48 0.6738 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 N24 mock treatment 193.9 7.71 0.04 184.1 -1.61 -0.01 0.0225 0.5485 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O01 compound treatment 285.0 98.8 0.52 284.4 98.7 0.51 0.7272 1.0 1304134 ChemDiv1_006293 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3C(C)CC(Nc4ccccc4)c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O02 compound treatment 281.4 95.2 0.5 283.1 97.4 0.51 0.7092 1.0 1418791 ChemDiv1_006294 O=C(CSc1nnc2n(Cc3ccccc3)c(=O)c4c5CCCCc5sc4n12)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O03 compound treatment 282.3 96.1 0.5 284.2 98.5 0.51 0.7165 0.9999 1669254 ChemDiv1_006295 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O04 compound treatment 283.6 97.4 0.51 282.7 97.0 0.5 0.7158 1.0 1446958 ChemDiv1_006296 O=C1NCCc2c1[nH]c3ccc(cc23)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O05 compound treatment 273.9 87.7 0.46 278.6 92.9 0.48 0.665 0.9996 1973226 ChemDiv1_006297 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O06 compound treatment 275.9 89.7 0.47 276.6 90.9 0.47 0.665 1.0 1333062 ChemDiv1_006298 CCOC(=O)c1c(C)n(C)c2c1cc(OC(=O)C)c3n(nc(c4ccccc4)c32)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O07 compound treatment 282.3 96.1 0.5 281.9 96.2 0.5 0.7081 1.0 1569005 ChemDiv1_006299 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(CC)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O08 compound treatment 280.5 94.3 0.49 283.1 97.4 0.51 0.7058 0.9999 1973227 ChemDiv1_006300 COc1ccc(cc1)c2cc(nc(SCC(=O)C)c2C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O09 compound treatment 275.6 89.4 0.47 279.8 94.1 0.49 0.6756 0.9997 1413740 ChemDiv1_006301 OC(=O)c1ccccc1C(=O)Nc2c(nc3ccccn23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O10 compound treatment 275.0 88.8 0.46 275.8 90.1 0.47 0.6587 1.0 1926925 ChemDiv1_006302 Clc1ccccc1c2nc3sc4CCCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O11 compound treatment 280.4 94.2 0.49 275.1 89.4 0.46 0.6761 0.9996 1973228 ChemDiv1_006303 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O12 compound treatment 279.6 93.4 0.49 276.7 91.0 0.47 0.679 0.9999 1289428 ChemDiv1_006304 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC(=O)C)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O13 compound treatment 343.7 158.0 0.82 343.8 158.0 0.82 1.1621 1.0 1973229 ChemDiv1_006305 CN1CCc2c(C1)sc3[nH]c(=S)n(C4CCCCC4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O14 compound treatment 279.3 93.1 0.49 274.3 88.6 0.46 0.6691 0.9996 1524157 ChemDiv1_006306 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O15 compound treatment 289.0 103.0 0.54 289.0 103.0 0.54 0.7589 1.0 1932186 ChemDiv1_006307 COc1ccc(cc1)n2c(=O)c3c4CCN(Cc5ccccc5)Cc4sc3[nH]c2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O16 compound treatment 278.8 92.6 0.48 277.4 91.7 0.48 0.6786 1.0 1657539 ChemDiv1_006308 CC1=C(C(NC(=O)N1)c2ccccc2OCc3ccccc3)C(=O)OCc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O17 compound treatment 291.2 105.0 0.55 289.3 104.0 0.54 0.7681 1.0 1973230 ChemDiv1_006309 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CC(C)(C)OCc3sc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O18 compound treatment 278.5 92.3 0.48 278.1 92.4 0.48 0.6801 1.0 1973231 ChemDiv1_006310 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O19 compound treatment 278.2 92.0 0.48 277.6 91.9 0.48 0.6771 1.0 1973232 ChemDiv1_006311 CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O20 compound treatment 277.7 91.5 0.48 279.7 94.0 0.49 0.683 0.9999 1432771 ChemDiv1_006312 COc1cc(Nc2nc3nonc3nc2N4CCCCC4C)c(OC)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O21 compound treatment 278.1 91.9 0.48 276.2 90.5 0.47 0.6716 1.0 1374638 ChemDiv1_006313 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O22 compound treatment 278.6 92.4 0.48 277.2 91.5 0.48 0.6771 1.0 1058931 ChemDiv1_006314 CC(=O)N1C(=O)C2(Nc3ccccc3N2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O23 mock treatment 280.7 94.5 0.49 277.2 91.5 0.48 0.6849 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 O24 mock treatment 95.3 -90.9 -0.47 98.2 -87.5 -0.45 -0.6569 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P01 compound treatment 283.8 97.6 0.51 284.5 98.8 0.51 0.7232 1.0 1973233 ChemDiv1_006315 COc1ccccc1NC(=O)CSc2nc3CCCCCc3cc2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P02 compound treatment 281.2 95.0 0.5 285.0 99.3 0.52 0.7154 0.9998 1604831 ChemDiv1_006316 COc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P03 compound treatment 283.0 96.8 0.5 284.9 99.2 0.52 0.7217 0.9999 1973234 ChemDiv1_006317 CCCCCCCCCN/C=C\1/Sc2ccc(OCC)cc2C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P04 compound treatment 282.9 96.7 0.5 285.5 99.8 0.52 0.7235 0.9999 1973235 ChemDiv1_006318 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OCc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P05 compound treatment 277.9 91.7 0.48 280.9 95.2 0.49 0.6882 0.9999 1543744 ChemDiv1_006319 O=C(CCN1C(=O)c2ccccc2C1=O)N3CCCc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P06 compound treatment 292.1 106.0 0.55 291.9 106.0 0.55 0.781 1.0 1973236 ChemDiv1_006320 Cc1cc(C=c2sc3nc4ccccc4n3c2=O)c(C)n1c5ccc(cc5)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P07 compound treatment 286.5 100.0 0.52 283.3 97.6 0.51 0.7287 0.9999 1973237 ChemDiv1_006321 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4ccc(cc4)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P08 compound treatment 281.7 95.5 0.5 285.5 99.8 0.52 0.7191 0.9998 1973238 ChemDiv1_006322 FC(F)(F)Oc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P09 compound treatment 304.5 118.0 0.62 304.1 118.0 0.62 0.8716 1.0 1973239 ChemDiv1_006323 CC(N1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCC(C)CC4)/SC1=S)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P10 compound treatment 277.9 91.7 0.48 279.8 94.1 0.49 0.6841 0.9999 1565833 ChemDiv1_006324 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P11 compound treatment 286.7 101.0 0.52 286.3 101.0 0.52 0.7405 1.0 1973240 ChemDiv1_006325 CC(C)N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N(C)Cc4ccccc4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P12 compound treatment 277.5 91.3 0.48 278.4 92.7 0.48 0.6775 1.0 1589589 ChemDiv1_006326 COc1ccc(OC)c(CNn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P13 compound treatment 278.2 92.0 0.48 279.4 93.7 0.49 0.6838 1.0 1973241 ChemDiv1_006327 CCCOc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P14 compound treatment 219.0 32.8 0.17 207.9 22.2 0.12 0.2026 0.9816 1173746 ChemDiv1_006328 CC1CCCCN1Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P15 compound treatment 277.9 91.7 0.48 285.4 99.7 0.52 0.7047 0.9992 1137124 ChemDiv1_006329 COc1ccc(cc1)c2nnc(Sc3nc4ccccc4o3)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P16 compound treatment 284.1 97.9 0.51 276.3 90.6 0.47 0.6941 0.9992 1973242 ChemDiv1_006330 COCCOC(=O)c1c(C)oc2ccc(OC(=O)c3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P17 compound treatment 283.1 96.9 0.51 279.1 93.4 0.49 0.7007 0.9998 1568255 ChemDiv1_006331 COc1ccc(cc1)c2nnc(Oc3ccc(C)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P18 compound treatment 287.0 101.0 0.53 266.4 80.7 0.42 0.6684 0.9937 1639090 ChemDiv1_006332 O=c1oc2cc(OCC#N)ccc2cc1c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P19 compound treatment 281.3 95.1 0.5 274.8 89.1 0.46 0.6783 0.9994 1262359 ChemDiv1_006333 CCOC(=O)Cc1nnc(Nc2cc(C)ccc2C)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P20 compound treatment 276.6 90.4 0.47 280.0 94.3 0.49 0.6801 0.9998 1217075 ChemDiv1_006334 COC(=O)c1c(C)oc2cc(Br)c(OCC(=O)c3ccc(OC)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P21 compound treatment 278.7 92.5 0.48 280.8 95.1 0.49 0.6907 0.9999 1943504 ChemDiv1_006335 OC(=O)c1cccnc1SC2CC(=O)N(C2=O)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P22 compound treatment 276.8 90.6 0.47 276.2 90.5 0.47 0.6668 1.0 1646668 ChemDiv1_006336 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OC(C)(C)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P23 mock treatment 281.3 95.1 0.5 278.0 92.3 0.48 0.69 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.604 P24 mock treatment 97.1 -89.1 -0.46 93.0 -92.7 -0.48 -0.6694 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A01 compound treatment 282.6 94.9 0.5 207.3 20.6 0.11 0.4258 0.8405 1259095 ChemDiv1_006337 CCOC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OC(C)(C)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A02 compound treatment 280.0 92.3 0.48 280.6 93.9 0.49 0.6856 1.0 1252103 ChemDiv1_006338 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccc(C)cc5c4=O)C(=O)CCC3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A03 compound treatment 282.2 94.5 0.49 284.1 97.4 0.51 0.7066 0.9999 1437380 ChemDiv1_006339 CCOc1ccc2nc(SCc3c(nnn3c4nonc4N)C(=O)OC)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A04 compound treatment 279.6 91.9 0.48 280.8 94.1 0.49 0.6848 1.0 1631298 ChemDiv1_006340 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2C)C(=O)Nc3ccccc3C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A05 compound treatment 283.8 96.1 0.5 286.1 99.4 0.52 0.7198 0.9999 1973243 ChemDiv1_006341 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A06 compound treatment 275.1 87.4 0.46 277.6 90.9 0.47 0.6565 0.9998 1151558 ChemDiv1_006342 Fc1ccc(Br)cc1C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A07 compound treatment 284.4 96.7 0.5 282.5 95.8 0.5 0.7088 1.0 1973244 ChemDiv1_006343 COc1ccccc1OCCOc2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A08 compound treatment 279.1 91.4 0.48 279.3 92.6 0.48 0.6775 1.0 1973245 ChemDiv1_006344 COC(=O)c1ccc(cc1)n2c(C)cc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccc5OCOc5c4)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A09 compound treatment 280.2 92.5 0.48 280.5 93.8 0.49 0.686 1.0 1664018 ChemDiv1_006345 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A10 compound treatment 282.3 94.6 0.49 277.2 90.5 0.47 0.6816 0.9997 1973246 ChemDiv1_006346 CC(=O)Nc1ccc2nc(SCc3c(Cl)cccc3[N+](=O)[O-])sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A11 compound treatment 286.1 98.4 0.51 276.0 89.3 0.46 0.6912 0.9987 1676253 ChemDiv1_006347 CC(=O)Nc1nc2[nH]c(C)c(Cc3ccccc3)c(=O)n2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A12 compound treatment 276.5 88.8 0.46 276.1 89.4 0.46 0.6561 1.0 1973247 ChemDiv1_006348 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc(Cl)ccc4O)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A13 compound treatment 304.9 117.0 0.61 306.5 120.0 0.62 0.8726 1.0 1973248 ChemDiv1_006349 CCOc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A14 compound treatment 284.6 96.9 0.51 287.0 100.0 0.52 0.7261 0.9999 1973249 ChemDiv1_006350 Clc1cccc(c1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4nccs4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A15 compound treatment 279.9 92.2 0.48 276.2 89.5 0.47 0.669 0.9999 1223853 ChemDiv1_006351 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cc5OCOc5cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A16 compound treatment 277.6 89.9 0.47 276.2 89.5 0.47 0.6606 1.0 1573956 ChemDiv1_006352 Cc1cccc(NC(=O)c2ccc3OCCOc3c2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A17 compound treatment 283.1 95.4 0.5 282.8 96.1 0.5 0.7051 1.0 1933212 ChemDiv1_006353 [O-][N+](=O)c1ccccc1c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A18 compound treatment 274.4 86.7 0.45 276.7 90.0 0.47 0.6506 0.9999 1642975 ChemDiv1_006354 Cn1c(Sc2nc3ccccc3n2CC(=O)N4CCOCC4)nc5n(C)c(=O)n(C)c(=O)c15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A19 compound treatment 281.4 93.7 0.49 281.2 94.5 0.49 0.693 1.0 1941979 ChemDiv1_006355 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A20 compound treatment 283.3 95.6 0.5 277.2 90.5 0.47 0.6853 0.9996 1973250 ChemDiv1_006356 Brc1cc(/C=C/2\NC(=S)NC2=O)cc(Br)c1OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A21 compound treatment 279.9 92.2 0.48 276.4 89.7 0.47 0.6698 0.9999 1973251 ChemDiv1_006357 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)c(Br)cc1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A22 compound treatment 276.3 88.6 0.46 267.0 80.3 0.42 0.622 0.9987 1324877 ChemDiv1_006358 COc1ccc(Cl)cc1NC(=O)CSc2nc3ccccc3[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A23 mock treatment 273.7 86.0 0.45 281.3 94.6 0.49 0.6649 0.999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 A24 mock treatment 76.2 -111.0 -0.58 78.7 -108.0 -0.56 -0.8083 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B01 compound treatment 281.6 93.9 0.49 276.2 89.5 0.47 0.6753 0.9997 1132172 ChemDiv1_006359 COc1ccc2[nH]c(SCC(=O)Nc3cc(Cl)ccc3OC)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B02 compound treatment 283.5 95.8 0.5 279.8 93.1 0.48 0.6956 0.9999 1150303 ChemDiv1_006360 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc(F)cc4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B03 compound treatment 281.1 93.4 0.49 285.6 98.9 0.51 0.708 0.9996 1587603 ChemDiv1_006361 Cc1nnc(SCC(=O)Nc2cc(NC(=O)CSc3nnc(C)s3)cc(c2)C(=O)O)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B04 compound treatment 281.7 94.0 0.49 281.4 94.7 0.49 0.6948 1.0 1464077 ChemDiv1_006362 Clc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B05 compound treatment 285.5 97.8 0.51 287.8 101.0 0.53 0.7323 0.9999 1360101 ChemDiv1_006363 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2OC(=O)c3ccc(Cl)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B06 compound treatment 281.9 94.2 0.49 281.7 95.0 0.49 0.6966 1.0 1645183 ChemDiv1_006364 COc1ccc(cc1CSc2nc3ccccc3o2)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B07 compound treatment 278.8 91.1 0.48 280.3 93.6 0.49 0.6801 0.9999 1466415 ChemDiv1_006365 CCNc1nc(NC(C)C)nc(Oc2ccccc2C(=O)OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B08 compound treatment 280.5 92.8 0.48 277.1 90.4 0.47 0.6746 0.9999 1573223 ChemDiv1_006366 CCOc1cc(ccc1OCc2ccccc2Cl)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B09 compound treatment 282.5 94.8 0.49 278.8 92.1 0.48 0.6882 0.9999 1410139 ChemDiv1_006367 Clc1ccc(cc1)c2nnc(Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B10 compound treatment 275.4 87.7 0.46 278.2 91.5 0.48 0.6598 0.9998 1341472 ChemDiv1_006368 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4cccc(OC)c4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B11 compound treatment 281.0 93.3 0.49 279.0 92.3 0.48 0.6834 1.0 1973252 ChemDiv1_006369 COCc1cc(C)nc2sc(c(NC(=O)c3ccccc3)c12)c4ccc(o4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B12 compound treatment 281.1 93.4 0.49 278.2 91.5 0.48 0.6808 0.9999 1155668 ChemDiv1_006370 COc1cc(CNn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B13 compound treatment 278.4 90.7 0.47 279.5 92.8 0.48 0.6756 1.0 1973253 ChemDiv1_006371 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)N4CCCc5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B14 compound treatment 277.9 90.2 0.47 279.1 92.4 0.48 0.6723 0.9999 1973254 ChemDiv1_006372 Clc1cccc(c1)N2CCN(CC2)C(=O)Cn3c4ccccc4c(=O)c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B15 compound treatment 278.9 91.2 0.48 278.8 92.1 0.48 0.6749 1.0 1973255 ChemDiv1_006373 CC(C)Cc1nnc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B16 compound treatment 280.3 92.6 0.48 274.4 87.7 0.46 0.6639 0.9996 1973256 ChemDiv1_006374 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(Oc5ccc(F)cc5F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B17 compound treatment 278.5 90.8 0.47 275.4 88.7 0.46 0.6609 0.9999 1973257 ChemDiv1_006375 CCOC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B18 compound treatment 280.5 92.8 0.48 278.1 91.4 0.48 0.6782 1.0 1628108 ChemDiv1_006376 Fc1cccc(Cl)c1Cc2nc3ccccc3[nH]c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B19 compound treatment 277.5 89.8 0.47 278.4 91.7 0.48 0.6683 1.0 1973258 ChemDiv1_006377 CCN(CC)Cc1c(O)ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc12)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B20 compound treatment 278.8 91.1 0.48 277.8 91.1 0.47 0.6709 1.0 1302671 ChemDiv1_006378 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2nc(cs2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B21 compound treatment 276.6 88.9 0.46 274.9 88.2 0.46 0.6521 1.0 1973259 ChemDiv1_006379 COc1ccc(cc1OC)c2c(oc3c(CN4CC(C)OC(C)C4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B22 compound treatment 280.0 92.3 0.48 278.4 91.7 0.48 0.6775 1.0 1973260 ChemDiv1_006380 Cc1cc(C)c(C#N)c(SCC(=O)Nc2c(Cl)cccc2Cl)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B23 mock treatment 279.9 92.2 0.48 274.2 87.5 0.45 0.6617 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 B24 mock treatment 81.0 -107.0 -0.56 78.2 -109.0 -0.56 -0.7924 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C01 compound treatment 281.2 93.5 0.49 282.9 96.2 0.5 0.6985 0.9999 1924863 ChemDiv1_006381 COCCOC(=O)c1c(C)oc2ccc(OCc3ccccc3Br)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C02 compound treatment 279.9 92.2 0.48 279.5 92.8 0.48 0.6812 1.0 1634153 ChemDiv1_006382 CCCOc1ccc(cc1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C03 compound treatment 285.9 98.2 0.51 283.7 97.0 0.5 0.7187 1.0 1973261 ChemDiv1_006383 COC(=O)c1nnn(c1CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C04 compound treatment 280.6 92.9 0.48 279.4 92.7 0.48 0.6834 1.0 1426575 ChemDiv1_006384 COc1ccc(cc1Br)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C05 compound treatment 280.3 92.6 0.48 278.1 91.4 0.48 0.6775 1.0 1973262 ChemDiv1_006385 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C06 compound treatment 278.0 90.3 0.47 276.5 89.8 0.47 0.6631 1.0 1256855 ChemDiv1_006386 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2C)C(=O)Nc3ccccc3C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C07 compound treatment 276.9 89.2 0.47 275.5 88.8 0.46 0.6554 1.0 1973263 ChemDiv1_006387 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCCOCCOc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C08 compound treatment 279.0 91.3 0.48 280.0 93.3 0.48 0.6797 1.0 1973264 ChemDiv1_006388 Cc1cc(ccc1Br)N2C(=O)NC(=O)/C(=C/c3ccccc3OCC#N)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C09 compound treatment 235.0 47.3 0.25 230.9 44.2 0.23 0.3369 0.9994 1251189 ChemDiv1_006389 Cc1oc2c(cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc24)c1C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C10 compound treatment 282.2 94.5 0.49 283.2 96.5 0.5 0.7033 1.0 1973265 ChemDiv1_006390 [O-][N+](=O)c1cc2OCOc2cc1/C=C/3\SC(=N)N(C3=O)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C11 compound treatment 283.7 96.0 0.5 275.9 89.2 0.46 0.682 0.9993 1973266 ChemDiv1_006391 CC(=O)/N=C/1\NC(=O)\C(=C\c2cc([N+](=O)[O-])c(cc2N3CCOCC3)N4CCOCC4)\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C12 compound treatment 306.0 118.0 0.62 304.5 118.0 0.61 0.8693 1.0 1973267 ChemDiv1_006392 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)cc(Br)c1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C13 compound treatment 350.6 163.0 0.85 350.6 164.0 0.85 1.2033 1.0 1973268 ChemDiv1_006393 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1OCc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C14 compound treatment 280.9 93.2 0.49 278.9 92.2 0.48 0.6827 1.0 1736578 ChemDiv1_006394 Clc1c(sc2ccccc12)C(=O)Nc3cccc(c3)c4nc5ncccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C15 compound treatment 285.7 98.0 0.51 289.5 103.0 0.53 0.7393 0.9998 1973269 ChemDiv1_006395 CCOc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C16 compound treatment 283.5 95.8 0.5 274.6 87.9 0.46 0.6764 0.999 1221744 ChemDiv1_006396 Clc1ccc(NC(=O)c2ccc3OCCOc3c2)nc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C17 compound treatment 291.9 104.0 0.54 290.5 104.0 0.54 0.7659 1.0 1933192 ChemDiv1_006397 OC(=O)c1ccccc1c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C18 compound treatment 275.8 88.1 0.46 274.2 87.5 0.45 0.6466 1.0 1973270 ChemDiv1_006398 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C19 compound treatment 279.2 91.5 0.48 282.4 95.7 0.5 0.6893 0.9998 1933239 ChemDiv1_006399 Fc1ccc(cc1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C20 compound treatment 280.3 92.6 0.48 273.6 86.9 0.45 0.661 0.9994 1524537 ChemDiv1_006400 Cc1ccc(C)c(NC(=O)CSc2nc3ccccc3o2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C21 compound treatment 295.2 108.0 0.56 294.4 108.0 0.56 0.7924 1.0 1973271 ChemDiv1_006401 CC(=O)/N=C/1\NC(=O)\C(=C/c2ccc(OCc3ccccc3)cc2)\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C22 compound treatment 277.7 90.0 0.47 273.5 86.8 0.45 0.651 0.9998 1704070 ChemDiv1_006402 Clc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C23 mock treatment 279.1 91.4 0.48 279.2 92.5 0.48 0.6771 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 C24 mock treatment 77.1 -111.0 -0.58 75.0 -112.0 -0.58 -0.8185 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D01 compound treatment 280.0 92.3 0.48 278.8 92.1 0.48 0.679 1.0 1973272 ChemDiv1_006403 COc1ccc2[nH]c(SCC(=O)Nc3ccc(Br)cc3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D02 compound treatment 284.2 96.5 0.5 284.1 97.4 0.51 0.7139 1.0 1621626 ChemDiv1_006404 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc(Cl)cc4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D03 compound treatment 280.0 92.3 0.48 281.4 94.7 0.49 0.6885 0.9999 1281074 ChemDiv1_006405 COc1ccc2[nH]c(SCC(=O)Nc3cccc(NC(=O)CSc4nc5cc(OC)ccc5[nH]4)n3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D04 compound treatment 279.7 92.0 0.48 281.5 94.8 0.49 0.6878 0.9999 1195053 ChemDiv1_006406 Cc1cccc(NC(=O)CC2SC(=O)NC2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D05 compound treatment 288.4 101.0 0.53 292.3 106.0 0.55 0.7596 0.9998 1260335 ChemDiv1_006407 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2OC(=O)c3ccccc3Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D06 compound treatment 282.2 94.5 0.49 280.3 93.6 0.49 0.6926 1.0 1520079 ChemDiv1_006408 COc1ccc(cc1Cn2nnc3ccccc23)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D07 compound treatment 282.2 94.5 0.49 276.3 89.6 0.47 0.6779 0.9996 1436118 ChemDiv1_006409 CCNc1nc(NCC)nc(Oc2ccccc2C(=O)OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D08 compound treatment 284.3 96.6 0.5 278.6 91.9 0.48 0.6941 0.9996 1262884 ChemDiv1_006410 COc1ccc(cc1COc2ccc(F)cc2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D09 compound treatment 278.8 91.1 0.48 278.7 92.0 0.48 0.6742 1.0 1124802 ChemDiv1_006411 COc1ccc(cc1)c2nnc(Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D10 compound treatment 276.7 89.0 0.46 282.4 95.7 0.5 0.68 0.9994 1531889 ChemDiv1_006412 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4cccc(C)c4C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D11 compound treatment 274.4 86.7 0.45 280.8 94.1 0.49 0.6657 0.9992 1232540 ChemDiv1_006413 COCc1cc(C)nc2sc(C(=O)c3ccc(Cl)cc3Cl)c(N)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D12 compound treatment 277.2 89.5 0.47 276.4 89.7 0.47 0.6598 1.0 1973273 ChemDiv1_006414 COc1cc(ccc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D13 compound treatment 283.2 95.5 0.5 279.6 92.9 0.48 0.6937 0.9999 1973274 ChemDiv1_006415 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)N4CCC(Cc5ccccc5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D14 compound treatment 278.1 90.4 0.47 277.5 90.8 0.47 0.6672 1.0 1973275 ChemDiv1_006416 CCOC(=O)C(NC(=O)Cn1c2ccccc2c(=O)c3ccccc13)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D15 compound treatment 292.9 105.0 0.55 287.4 101.0 0.52 0.7582 0.9997 1973276 ChemDiv1_006417 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)Nc4nc(cs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D16 compound treatment 277.8 90.1 0.47 278.4 91.7 0.48 0.6694 1.0 1973277 ChemDiv1_006418 Clc1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)ccc1Oc5ccc6ccccc6c5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D17 compound treatment 278.5 90.8 0.47 275.4 88.7 0.46 0.6609 0.9999 1973278 ChemDiv1_006419 CCOC(=O)C(C)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D18 compound treatment 279.5 91.8 0.48 277.9 91.2 0.47 0.6738 1.0 1736638 ChemDiv1_006420 Cc1cc2nc(Cc3ccc(Cl)cc3Cl)c(=O)[nH]c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D19 compound treatment 281.9 94.2 0.49 277.7 91.0 0.47 0.6819 0.9998 1973279 ChemDiv1_006421 COCCN(CCOC)Cc1c(O)ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc12)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D20 compound treatment 279.2 91.5 0.48 278.8 92.1 0.48 0.676 1.0 1396891 ChemDiv1_006422 O=C(CSc1nc2ccccc2o1)N3CCc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D21 compound treatment 281.9 94.2 0.49 275.9 89.2 0.46 0.6753 0.9996 1313887 ChemDiv1_006423 O=C(Nc1nc(cs1)c2ccccc2)C3COc4ccccc4O3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D22 compound treatment 276.1 88.4 0.46 274.2 87.5 0.45 0.6477 1.0 1973280 ChemDiv1_006424 CCOc1ccc(OCC)c(c1)N2C(=O)NC(=O)/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D23 mock treatment 278.2 90.5 0.47 276.0 89.3 0.46 0.662 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 D24 mock treatment 81.6 -106.0 -0.55 78.9 -108.0 -0.56 -0.7876 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E01 compound treatment 281.7 94.0 0.49 249.7 63.0 0.33 0.5783 0.9807 1925059 ChemDiv1_006425 COCCOC(=O)c1c(C)oc2ccc(OCc3cccc(Br)c3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E02 compound treatment 284.5 96.8 0.51 283.5 96.8 0.5 0.7128 1.0 1552131 ChemDiv1_006426 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)ccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E03 compound treatment 284.0 96.3 0.5 282.4 95.7 0.5 0.707 1.0 1973281 ChemDiv1_006427 CC(C)OC(=O)c1nnn(c1CSc2nc3ccccc3o2)c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E04 compound treatment 280.1 92.4 0.48 282.5 95.8 0.5 0.6929 0.9999 1271571 ChemDiv1_006428 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2OC)C(=O)Nc3ccccc3C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E05 compound treatment 284.0 96.3 0.5 281.0 94.3 0.49 0.7018 0.9999 1128436 ChemDiv1_006429 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OC(=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E06 compound treatment 277.1 89.4 0.47 279.2 92.5 0.48 0.6697 0.9999 1581013 ChemDiv1_006430 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OC5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E07 compound treatment 286.8 99.1 0.52 278.3 91.6 0.48 0.7022 0.9991 1973282 ChemDiv1_006431 COc1cccc(OCCOc2ccc(cc2C=c3sc4nc5ccccc5n4c3=O)[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E08 compound treatment 281.3 93.6 0.49 279.3 92.6 0.48 0.6856 1.0 1973283 ChemDiv1_006432 CCOC(=O)CSc1nc2ccc(NC(=O)CSc3nc4sc5CCCCc5c4c(=O)n3C)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E09 compound treatment 276.5 88.8 0.46 280.8 94.1 0.49 0.6734 0.9996 1973284 ChemDiv1_006433 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cccc4C(=O)c5ccccc5C(=O)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E10 compound treatment 411.8 224.0 1.17 422.8 236.0 1.23 1.6944 0.9997 1677922 ChemDiv1_006434 COc1cc(C=c2sc3nc4c(C)cc(C)cc4n3c2=O)cc(Br)c1OCC#C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E11 compound treatment 282.8 95.1 0.5 281.0 94.3 0.49 0.6974 1.0 1973285 ChemDiv1_006435 CC/N=C/1\S/C(=C\c2cc3OCOc3cc2Br)/C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E12 compound treatment 277.1 89.4 0.47 279.4 92.7 0.48 0.6705 0.9999 1973286 ChemDiv1_006436 COc1ccc(cc1[N+](=O)[O-])C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E13 compound treatment 282.6 94.9 0.5 277.1 90.4 0.47 0.6823 0.9997 1335771 ChemDiv1_006437 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(F)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E14 compound treatment 279.2 91.5 0.48 280.9 94.2 0.49 0.6837 0.9999 1728772 ChemDiv1_006438 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)c4nc5ncccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E15 compound treatment 281.4 93.7 0.49 277.9 91.2 0.47 0.6808 0.9999 1973287 ChemDiv1_006439 CCOC(=O)c1ccc(cc1)c2ccc(/C=C/3\S\C(=N\C)\N(C)C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E16 compound treatment 284.1 96.4 0.5 281.7 95.0 0.49 0.7048 1.0 1927410 ChemDiv1_006440 [O-][N+](=O)c1cc(NC(=O)c2ccc3OCCOc3c2)ccc1F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E17 compound treatment 286.5 98.8 0.52 283.5 96.8 0.5 0.7202 0.9999 1973288 ChemDiv1_006441 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E18 compound treatment 277.5 89.8 0.47 278.3 91.6 0.48 0.6679 1.0 1973289 ChemDiv1_006442 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Br)c1OCC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E19 compound treatment 284.3 96.6 0.5 280.9 94.2 0.49 0.7026 0.9999 1706513 ChemDiv1_006443 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E20 compound treatment 279.1 91.4 0.48 281.5 94.8 0.49 0.6856 0.9999 1433732 ChemDiv1_006444 CC(=O)Nc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E21 compound treatment 277.7 90.0 0.47 280.4 93.7 0.49 0.6764 0.9998 1973290 ChemDiv1_006445 Cc1cc(/C=C/2\NC(=O)NC2=O)c(C)n1c3ccc(cc3)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E22 compound treatment 277.0 89.3 0.47 277.0 90.3 0.47 0.6613 1.0 1663539 ChemDiv1_006446 COc1ccc(Cl)cc1NC(=O)CSc2nc3cc(C)ccc3[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E23 mock treatment 278.8 91.1 0.48 279.6 92.9 0.48 0.6775 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 E24 mock treatment 79.3 -108.0 -0.57 78.9 -108.0 -0.56 -0.7961 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F01 compound treatment 286.6 98.9 0.52 285.1 98.4 0.51 0.7265 1.0 1123022 ChemDiv1_006447 COc1ccc2[nH]c(SCC(=O)Nc3ccccc3Br)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F02 compound treatment 279.7 92.0 0.48 281.3 94.6 0.49 0.6871 0.9999 1407862 ChemDiv1_006448 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccccc4F)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F03 compound treatment 279.4 91.7 0.48 282.6 95.9 0.5 0.6907 0.9998 1973291 ChemDiv1_006449 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F04 compound treatment 282.1 94.4 0.49 284.1 97.4 0.51 0.7062 0.9999 1659856 ChemDiv1_006450 Cc1ccccc1NC(=O)CC2SC(=O)NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F05 compound treatment 285.3 97.6 0.51 282.9 96.2 0.5 0.7136 1.0 1415095 ChemDiv1_006451 COc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F06 compound treatment 282.5 94.8 0.49 280.6 93.9 0.49 0.6948 1.0 1973292 ChemDiv1_006452 COc1ccc(cc1Cn2nc(C)c([N+](=O)[O-])c2C)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F07 compound treatment 277.9 90.2 0.47 276.9 90.2 0.47 0.6642 1.0 1157320 ChemDiv1_006453 CCOC(=O)c1ccc(Oc2nc(NC(C)C)nc(NC(C)C)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F08 compound treatment 282.1 94.4 0.49 279.8 93.1 0.48 0.6904 1.0 1604717 ChemDiv1_006454 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F09 compound treatment 280.0 92.3 0.48 283.4 96.7 0.5 0.6959 0.9998 1262179 ChemDiv1_006455 Cc1ccc(cc1S(=O)(=O)N)c2nnc(N3CCOCC3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F10 compound treatment 280.9 93.2 0.49 279.9 93.2 0.48 0.6863 1.0 1693689 ChemDiv1_006456 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F11 compound treatment 277.8 90.1 0.47 276.1 89.4 0.46 0.6609 1.0 1973293 ChemDiv1_006457 COc1ccc(/C=C(\C#N)/C(=O)Nc2ncc(Cc3cc(Cl)ccc3Cl)s2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F12 compound treatment 281.5 93.8 0.49 281.4 94.7 0.49 0.6941 1.0 1973294 ChemDiv1_006458 Ic1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F13 compound treatment 277.8 90.1 0.47 278.1 91.4 0.48 0.6683 1.0 1973295 ChemDiv1_006459 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F14 compound treatment 286.8 99.1 0.52 277.7 91.0 0.47 0.7 0.999 1973296 ChemDiv1_006460 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(Oc5ccc(Cl)c(Cl)c5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F15 compound treatment 288.8 101.0 0.53 287.9 101.0 0.53 0.7449 1.0 1973297 ChemDiv1_006461 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F16 compound treatment 278.1 90.4 0.47 279.3 92.6 0.48 0.6738 0.9999 1973298 ChemDiv1_006462 [O-][N+](=O)c1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F17 compound treatment 280.3 92.6 0.48 278.6 91.9 0.48 0.6793 1.0 1973299 ChemDiv1_006463 CCC(=O)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F18 compound treatment 277.4 89.7 0.47 281.2 94.5 0.49 0.6782 0.9997 1442755 ChemDiv1_006464 COc1ccc(OC)c(Cc2nc3cc(C)c(C)cc3[nH]c2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F19 compound treatment 278.9 91.2 0.48 275.4 88.7 0.46 0.6624 0.9999 1973300 ChemDiv1_006465 COc1ccc(cc1OC)c2c(oc3c(CN4CCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F20 compound treatment 280.6 92.9 0.48 276.0 89.3 0.46 0.6709 0.9998 1380420 ChemDiv1_006466 O=C(CSc1ncn[nH]1)N2c3ccccc3Sc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F21 compound treatment 408.7 221.0 1.15 406.8 220.0 1.14 1.6242 1.0 1973301 ChemDiv1_006467 COC(=O)CCCCCN1C(=O)/C(=C\c2cc(Br)c(O)c(OC)c2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F22 compound treatment 279.8 92.1 0.48 277.4 90.7 0.47 0.6731 1.0 1973302 ChemDiv1_006468 CCOc1cccc(c1)N2C(=O)/C(=C/c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F23 mock treatment 279.2 91.5 0.48 281.0 94.3 0.49 0.6841 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 F24 mock treatment 79.6 -108.0 -0.56 79.6 -107.0 -0.56 -0.7924 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G01 compound treatment 282.6 94.9 0.5 287.7 101.0 0.52 0.7213 0.9996 1924644 ChemDiv1_006469 CCOC(=O)c1c(oc2cc(Br)c(OC(C)C(=O)OC)cc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G02 compound treatment 281.9 94.2 0.49 285.6 98.9 0.51 0.711 0.9997 1407057 ChemDiv1_006470 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)c(OC)c2)C(=O)Nc3ccc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G03 compound treatment 283.1 95.4 0.5 285.0 98.3 0.51 0.7132 0.9999 1231067 ChemDiv1_006471 O=C(CSc1nc2ccccc2[nH]1)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G04 compound treatment 282.9 95.2 0.5 284.0 97.3 0.51 0.7088 1.0 1421622 ChemDiv1_006472 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(C)cc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G05 compound treatment 280.8 93.1 0.49 282.1 95.4 0.5 0.6941 0.9999 1942267 ChemDiv1_006473 CC/1=NN(C(=O)\C1=C\c2ccc(OS(=O)(=O)c3ccccc3[N+](=O)[O-])cc2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G06 compound treatment 296.0 108.0 0.57 292.8 106.0 0.55 0.7895 0.9999 1930586 ChemDiv1_006474 Brc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G07 compound treatment 283.3 95.6 0.5 277.6 90.9 0.47 0.6867 0.9996 1973303 ChemDiv1_006475 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Cl)c1OCCOc5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G08 compound treatment 280.9 93.2 0.49 275.4 88.7 0.46 0.6698 0.9996 1521979 ChemDiv1_006476 O=C(CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1)NCc6ccco6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G09 compound treatment 284.4 96.7 0.5 282.9 96.2 0.5 0.7103 1.0 1214543 ChemDiv1_006477 Cc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2c1C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G10 compound treatment 283.3 95.6 0.5 280.6 93.9 0.49 0.6978 0.9999 1973304 ChemDiv1_006478 CC/N=C/1\S/C(=C\c2ccc(o2)c3ccc(Cl)c(c3)[N+](=O)[O-])/C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G11 compound treatment 352.5 165.0 0.86 348.8 162.0 0.84 1.2037 0.9999 1973305 ChemDiv1_006479 COc1cc(c2ccc(/C=C/3\S\C(=N\C(=O)C)\NC3=O)o2)c(OC)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G12 compound treatment 349.0 161.0 0.84 349.2 162.0 0.84 1.1923 1.0 1973306 ChemDiv1_006480 CCOC(=O)Cn1cc(/C=C/2\Sc3ccccc3C2=O)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G13 compound treatment 281.0 93.3 0.49 275.1 88.4 0.46 0.6691 0.9996 1973307 ChemDiv1_006481 Cc1ccsc1C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G14 compound treatment 281.0 93.3 0.49 277.6 90.9 0.47 0.6783 0.9999 1973308 ChemDiv1_006482 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G15 compound treatment 283.5 95.8 0.5 281.1 94.4 0.49 0.7003 1.0 1973309 ChemDiv1_006483 COc1cccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G16 compound treatment 276.0 88.3 0.46 279.1 92.4 0.48 0.6653 0.9998 1516302 ChemDiv1_006484 CCCOC(=O)c1ccc(NC(=O)c2ccc3OCCOc3c2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G17 compound treatment 283.3 95.6 0.5 286.9 100.0 0.52 0.7209 0.9998 1933241 ChemDiv1_006485 COc1ccc(OC)c(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G18 compound treatment 278.0 90.3 0.47 278.3 91.6 0.48 0.6698 1.0 1973310 ChemDiv1_006486 CCCOc1c(Br)cc(C=C2C(=O)NC(=O)NC2=O)cc1OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G19 compound treatment 327.7 140.0 0.73 324.1 137.0 0.71 1.0214 0.9999 1973311 ChemDiv1_006487 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1OCc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G20 compound treatment 273.6 85.9 0.45 277.2 90.5 0.47 0.6495 0.9997 1400839 ChemDiv1_006488 NC(=O)c1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G21 compound treatment 281.8 94.1 0.49 280.0 93.3 0.48 0.69 1.0 1973312 ChemDiv1_006489 COc1ccc2[nH]c-3c(CCn4c3nc5sc6CCCCc6c5c4=N)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G22 compound treatment 276.1 88.4 0.46 276.9 90.2 0.47 0.6576 1.0 1731654 ChemDiv1_006490 Cc1ccc2[nH]c(SCC(=O)Nc3cccc(Cl)c3C)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G23 mock treatment 283.0 95.3 0.5 280.1 93.4 0.49 0.6948 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 G24 mock treatment 80.7 -107.0 -0.56 76.7 -110.0 -0.57 -0.799 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H01 compound treatment 282.5 94.8 0.49 287.6 101.0 0.52 0.7205 0.9996 1347885 ChemDiv1_006491 CCOc1ccc2nc(SCC(=O)Nc3ccc(NC(=O)C)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H02 compound treatment 277.4 89.7 0.47 283.5 96.8 0.5 0.6867 0.9993 1642811 ChemDiv1_006492 COc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H03 compound treatment 280.7 93.0 0.49 277.0 90.3 0.47 0.6749 0.9999 1973313 ChemDiv1_006493 COC(=O)C1=C(C)OC(=C(C#N)C1C2CCCCC2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H04 compound treatment 279.7 92.0 0.48 283.3 96.6 0.5 0.6944 0.9997 1724260 ChemDiv1_006494 Oc1cccc(NC(=O)CC2SC(=O)N(C2=O)c3ccccc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H05 compound treatment 283.2 95.5 0.5 283.6 96.9 0.5 0.7084 1.0 1973314 ChemDiv1_006495 COc1ccc(OC)c(c1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H06 compound treatment 282.2 94.5 0.49 281.4 94.7 0.49 0.6966 1.0 1579110 ChemDiv1_006496 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H07 compound treatment 277.8 90.1 0.47 277.6 90.9 0.47 0.6664 1.0 1221521 ChemDiv1_006497 CCNc1nc(NCC)nc(Oc2ccc(cc2)C(=O)OCC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H08 compound treatment 284.5 96.8 0.51 282.2 95.5 0.5 0.7081 1.0 1932107 ChemDiv1_006498 COc1ccc(cc1COc2ccc([N+](=O)[O-])c(C)c2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H09 compound treatment 278.0 90.3 0.47 280.4 93.7 0.49 0.6775 0.9999 1717075 ChemDiv1_006499 CNS(=O)(=O)c1cc(ccc1C)c2nnc(N3CCOCC3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H10 compound treatment 279.3 91.6 0.48 278.4 91.7 0.48 0.6749 1.0 1518824 ChemDiv1_006500 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cc(Br)ccc4O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H11 compound treatment 205.3 17.6 0.09 218.3 31.6 0.16 0.1811 0.9624 1973315 ChemDiv1_006501 CCOC(=O)CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H12 compound treatment 286.0 98.3 0.51 283.1 96.4 0.5 0.7169 0.9999 1973316 ChemDiv1_006502 Clc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c(c1)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H13 compound treatment 280.0 92.3 0.48 282.6 95.9 0.5 0.6929 0.9999 1973317 ChemDiv1_006503 Cc1cc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H14 compound treatment 279.5 91.8 0.48 279.7 93.0 0.48 0.6804 1.0 1973318 ChemDiv1_006504 Cn1nc(cc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H15 compound treatment 283.3 95.6 0.5 275.7 89.0 0.46 0.6798 0.9993 1973319 ChemDiv1_006505 CCN(Cc1ccccc1)C(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H16 compound treatment 280.0 92.3 0.48 275.0 88.3 0.46 0.665 0.9997 1305448 ChemDiv1_006506 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H17 compound treatment 280.2 92.5 0.48 279.6 92.9 0.48 0.6827 1.0 1973320 ChemDiv1_006507 CCCC(=O)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H18 compound treatment 278.3 90.6 0.47 279.9 93.2 0.48 0.6767 0.9999 1973321 ChemDiv1_006508 Cc1ccc2n(CC(=O)Nc3ccc(F)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H19 compound treatment 277.0 89.3 0.47 278.1 91.4 0.48 0.6653 1.0 1973322 ChemDiv1_006509 COc1ccc(cc1OC)c2c(oc3c(CN4CCCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H20 compound treatment 280.9 93.2 0.49 279.1 92.4 0.48 0.6834 1.0 1368893 ChemDiv1_006510 Cc1ccc(C#N)c(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H21 compound treatment 282.5 94.8 0.49 282.5 95.8 0.5 0.7018 1.0 1726934 ChemDiv1_006511 Cc1ccc(cc1NC(=O)c2sc3ccccc3c2Cl)c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H22 compound treatment 278.7 91.0 0.47 279.5 92.8 0.48 0.6768 1.0 1973323 ChemDiv1_006512 CCOc1ccc(OCC)c(c1)N2C(=O)NC(=O)/C(=C\c3ccc4OCOc4c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H23 mock treatment 279.8 92.1 0.48 283.2 96.5 0.5 0.6944 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 H24 mock treatment 83.0 -105.0 -0.55 77.8 -109.0 -0.57 -0.7865 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I01 compound treatment 288.7 101.0 0.53 284.2 97.5 0.51 0.7309 0.9998 1973324 ChemDiv1_006513 CCOC(=O)c1c(oc2cc(Br)c(OCC(=O)OC)cc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I02 compound treatment 280.3 92.6 0.48 280.4 93.7 0.49 0.686 1.0 1973325 ChemDiv1_006514 CC(C)OCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I03 compound treatment 284.6 96.9 0.51 281.1 94.4 0.49 0.7044 0.9999 1468591 ChemDiv1_006515 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OC(=O)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I04 compound treatment 283.3 95.6 0.5 283.0 96.3 0.5 0.7066 1.0 1394260 ChemDiv1_006516 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I05 compound treatment 280.8 93.1 0.49 278.3 91.6 0.48 0.6801 0.9999 1973326 ChemDiv1_006517 CC/1=NN(C(=O)\C1=C/c2ccccc2OS(=O)(=O)c3ccccc3[N+](=O)[O-])c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I06 compound treatment 286.2 98.5 0.51 279.5 92.8 0.48 0.7044 0.9995 1973327 ChemDiv1_006518 [O-][N+](=O)c1cccc(c1)n2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I07 compound treatment 279.6 91.9 0.48 279.2 92.5 0.48 0.679 1.0 1973328 ChemDiv1_006519 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Cl)c1OCCOc5ccccc5C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I08 compound treatment 279.5 91.8 0.48 279.7 93.0 0.48 0.6804 1.0 1973329 ChemDiv1_006520 O=C(CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1)NC6CC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I09 compound treatment 284.1 96.4 0.5 281.9 95.2 0.49 0.7055 1.0 1973330 ChemDiv1_006521 CC(=O)Nc1ccc(cc1)n2c(=O)c3ccc4c(=O)n(c5ccc(NC(=O)C)cc5)c(=O)c6ccc(c2=O)c3c46 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I10 compound treatment 317.0 129.0 0.67 309.6 123.0 0.64 0.9287 0.9996 1973331 ChemDiv1_006522 CCOc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)c(Br)cc1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I11 compound treatment 284.4 96.7 0.5 284.0 97.3 0.51 0.7143 1.0 1700914 ChemDiv1_006523 Cn1c(SCc2cc3OCOc3cc2Cl)nc4n(C)c(=O)n(C)c(=O)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I12 compound treatment 280.8 93.1 0.49 280.0 93.3 0.48 0.6863 1.0 1298193 ChemDiv1_006524 Cn1ccnc1Sc2nc(Nc3cccc(Cl)c3)nc(n2)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I13 compound treatment 283.4 95.7 0.5 282.5 95.8 0.5 0.7051 1.0 1973332 ChemDiv1_006525 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I14 compound treatment 278.5 90.8 0.47 276.8 90.1 0.47 0.6661 1.0 1930478 ChemDiv1_006526 [O-][N+](=O)c1cc(Cl)ccc1N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I15 compound treatment 280.1 92.4 0.48 282.3 95.6 0.5 0.6922 0.9999 1973333 ChemDiv1_006527 COc1ccc(OC)c(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I16 compound treatment 277.5 89.8 0.47 281.5 94.8 0.49 0.6797 0.9997 1973334 ChemDiv1_006528 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3ccc4OCCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I17 compound treatment 344.9 157.0 0.82 352.2 165.0 0.86 1.1882 0.9997 1973335 ChemDiv1_006529 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(Br)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I18 compound treatment 278.7 91.0 0.47 276.4 89.7 0.47 0.6654 1.0 1973336 ChemDiv1_006530 CCCOc1c(Br)cc(C=C2C(=O)NC(=S)NC2=O)cc1OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I19 compound treatment 281.8 94.1 0.49 268.0 81.3 0.42 0.6459 0.9972 1973337 ChemDiv1_006531 Cc1ccsc1/C=C/2\Sc3ccccc3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I20 compound treatment 277.0 89.3 0.47 275.2 88.5 0.46 0.6547 1.0 1393164 ChemDiv1_006532 COc1ccc(Cl)cc1NC(=O)CSc2nc3ccccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I21 compound treatment 279.6 91.9 0.48 276.7 90.0 0.47 0.6698 0.9999 1136641 ChemDiv1_006533 COc1ccc2[nH]c-3c(CCn4c3nc5sc6CCCCCc6c5c4=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I22 compound treatment 278.9 91.2 0.48 274.0 87.3 0.45 0.6573 0.9997 1933798 ChemDiv1_006534 Cc1ccc2[nH]c(SCC(=O)Nc3ccc(Br)cc3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I23 mock treatment 281.7 94.0 0.49 278.9 92.2 0.48 0.6856 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 I24 mock treatment 78.5 -109.0 -0.57 84.6 -102.0 -0.53 -0.7781 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J01 compound treatment 285.0 97.3 0.51 284.0 97.3 0.51 0.7165 1.0 1396822 ChemDiv1_006535 CCOc1ccc2nc(SCC(=O)Nc3cc(Cl)ccc3OC)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J02 compound treatment 281.0 93.3 0.49 283.8 97.1 0.5 0.701 0.9998 1723896 ChemDiv1_006536 CCOc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J03 compound treatment 278.3 90.6 0.47 278.3 91.6 0.48 0.6709 1.0 1973338 ChemDiv1_006537 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2OC)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J04 compound treatment 279.1 91.4 0.48 284.1 97.4 0.51 0.6951 0.9996 1973339 ChemDiv1_006538 COC(=O)CC1SC(=O)N(CNc2ccc(cc2)[N+](=O)[O-])C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J05 compound treatment 284.1 96.4 0.5 279.4 92.7 0.48 0.6963 0.9998 1642304 ChemDiv1_006539 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J06 compound treatment 282.0 94.3 0.49 276.8 90.1 0.47 0.679 0.9997 1463088 ChemDiv1_006540 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J07 compound treatment 275.8 88.1 0.46 278.4 91.7 0.48 0.662 0.9998 1632265 ChemDiv1_006541 CCNc1nc(NC(C)C)nc(Oc2ccc(cc2)C(=O)OCC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J08 compound treatment 284.9 97.2 0.51 280.8 94.1 0.49 0.7044 0.9998 1926605 ChemDiv1_006542 COc1ccc(cc1COc2ccc(cc2)[N+](=O)[O-])C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J09 compound treatment 282.9 95.2 0.5 282.9 96.2 0.5 0.7047 1.0 1973340 ChemDiv1_006543 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3F)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J10 compound treatment 277.9 90.2 0.47 276.8 90.1 0.47 0.6639 1.0 1973341 ChemDiv1_006544 COc1ccc(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J11 compound treatment 329.3 142.0 0.74 330.7 144.0 0.75 1.0516 1.0 1973342 ChemDiv1_006545 CN(C)CCOC(=O)CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J12 compound treatment 279.5 91.8 0.48 279.1 92.4 0.48 0.6782 1.0 1973343 ChemDiv1_006546 FC(F)(F)Oc1cccc(CNC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J13 compound treatment 284.2 96.5 0.5 284.4 97.7 0.51 0.715 1.0 1973344 ChemDiv1_006547 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)NC4=NCCS4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J14 compound treatment 285.2 97.5 0.51 282.3 95.6 0.5 0.711 0.9999 1973345 ChemDiv1_006548 FC(F)(F)Oc1cc(Br)ccc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J15 compound treatment 279.4 91.7 0.48 280.8 94.1 0.49 0.6841 0.9999 1973346 ChemDiv1_006549 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)N(CCC#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J16 compound treatment 279.9 92.2 0.48 280.0 93.3 0.48 0.683 1.0 1524818 ChemDiv1_006550 COc1cccc(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J17 compound treatment 285.2 97.5 0.51 282.4 95.7 0.5 0.7114 0.9999 1973347 ChemDiv1_006551 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)C(C)C)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J18 compound treatment 282.5 94.8 0.49 279.0 92.3 0.48 0.6889 0.9999 1154272 ChemDiv1_006552 Cc1cc2nc(Cc3ccc4OCOc4c3)c(=O)[nH]c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J19 compound treatment 277.1 89.4 0.47 278.6 91.9 0.48 0.6675 0.9999 1973348 ChemDiv1_006553 COc1ccc(cc1OC)c2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J20 compound treatment 281.9 94.2 0.49 275.5 88.8 0.46 0.6739 0.9995 1241593 ChemDiv1_006554 Cc1ccc2c(N)c(sc2n1)C(=O)N3c4ccccc4Sc5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J21 compound treatment 277.2 89.5 0.47 276.5 89.8 0.47 0.6602 1.0 1304536 ChemDiv1_006555 Clc1c(sc2ccccc12)C(=O)Nc3ccc(Cl)c(c3)c4nc5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J22 compound treatment 295.9 108.0 0.56 294.7 108.0 0.56 0.7961 1.0 1973349 ChemDiv1_006556 CCOc1ccc(OCC)c(c1)N2C(=O)NC(=O)/C(=C\C=C\c3ccco3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J23 mock treatment 276.2 88.5 0.46 277.1 90.4 0.47 0.6587 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 J24 mock treatment 80.3 -107.0 -0.56 77.0 -110.0 -0.57 -0.7994 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K01 compound treatment 286.8 99.1 0.52 288.3 102.0 0.53 0.739 0.9999 1256632 ChemDiv1_006557 Cc1ccc(cc1)C(=O)c2oc3ccc(Cl)cc3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K02 compound treatment 280.6 92.9 0.48 278.4 91.7 0.48 0.6797 1.0 1580005 ChemDiv1_006558 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Cl)c(O)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K03 compound treatment 281.0 93.3 0.49 279.2 92.5 0.48 0.6841 1.0 1973350 ChemDiv1_006559 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K04 compound treatment 281.9 94.2 0.49 276.3 89.6 0.47 0.6768 0.9996 1566250 ChemDiv1_006560 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K05 compound treatment 331.5 144.0 0.75 345.5 159.0 0.83 1.1141 0.9989 1973351 ChemDiv1_006561 CCOc1cc(/C=C\2/SC(=S)NC2=O)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K06 compound treatment 277.8 90.1 0.47 278.3 91.6 0.48 0.669 1.0 1973352 ChemDiv1_006562 COc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(C)c3)c(cc1OC)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K07 compound treatment 279.6 91.9 0.48 278.8 92.1 0.48 0.6775 1.0 1973353 ChemDiv1_006563 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K08 compound treatment 286.5 98.8 0.52 280.9 94.2 0.49 0.7107 0.9997 1535493 ChemDiv1_006564 CCSc1nc2ccc(NC(=O)c3ccccc3C(=O)N4CCCCC4)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K09 compound treatment 282.2 94.5 0.49 280.4 93.7 0.49 0.693 1.0 1635171 ChemDiv1_006565 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K10 compound treatment 284.5 96.8 0.51 279.7 93.0 0.48 0.6989 0.9998 1973354 ChemDiv1_006566 CC/1=NN(C(=O)\C1=C/c2cnn(c2)c3ccc(C)c(C)c3)c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K11 compound treatment 278.0 90.3 0.47 280.6 93.9 0.49 0.6782 0.9998 1159821 ChemDiv1_006567 CN(C)C(=O)Oc1cccc(c1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K12 compound treatment 278.7 91.0 0.47 280.2 93.5 0.49 0.6793 0.9999 1319539 ChemDiv1_006568 C1CN(CCO1)c2nc(nc(n2)n3cccn3)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K13 compound treatment 285.3 97.6 0.51 283.2 96.5 0.5 0.7147 1.0 1973355 ChemDiv1_006569 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K14 compound treatment 279.5 91.8 0.48 283.4 96.7 0.5 0.694 0.9997 1936006 ChemDiv1_006570 Cc1c(Cl)cccc1c2ccc(o2)C(=O)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K15 compound treatment 294.4 107.0 0.56 295.7 109.0 0.57 0.7942 1.0 1973356 ChemDiv1_006571 CCOC(=O)c1ccc(cc1)c2ccc(/C=C/3\S\C(=N\C(=O)C)\NC3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K16 compound treatment 278.7 91.0 0.47 274.4 87.7 0.46 0.658 0.9998 1667149 ChemDiv1_006572 COC(=O)c1cc(NC(=O)c2ccc3OCCOc3c2)cc(c1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K17 compound treatment 364.2 177.0 0.92 349.1 162.0 0.84 1.248 0.9991 1973357 ChemDiv1_006573 COc1cc(C=c2sc3nc4c(Br)c(C)c(C)cc4n3c2=O)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K18 compound treatment 280.4 92.7 0.48 281.7 95.0 0.49 0.6911 0.9999 1973358 ChemDiv1_006574 CCCOc1c(Br)cc(/C=C/2\NC(=S)NC2=O)cc1OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K19 compound treatment 306.6 119.0 0.62 320.6 134.0 0.7 0.9307 0.9984 1418681 ChemDiv1_006575 COc1cc(OC)c(cc1OC)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K20 compound treatment 281.9 94.2 0.49 279.8 93.1 0.48 0.6897 1.0 1973359 ChemDiv1_006576 Brc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K21 compound treatment 281.1 93.4 0.49 276.3 89.6 0.47 0.6738 0.9997 1297726 ChemDiv1_006577 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)c(OC)c2)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K22 compound treatment 277.4 89.7 0.47 275.4 88.7 0.46 0.6569 1.0 1376487 ChemDiv1_006578 Cc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K23 mock treatment 279.6 91.9 0.48 280.1 93.4 0.49 0.6823 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 K24 mock treatment 78.9 -109.0 -0.57 78.3 -108.0 -0.56 -0.7998 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L01 compound treatment 281.5 93.8 0.49 281.5 94.8 0.49 0.6944 1.0 1658171 ChemDiv1_006579 CCOc1ccc2nc(SCC(=O)Nc3cccc(SC)c3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L02 compound treatment 287.6 99.9 0.52 280.9 94.2 0.49 0.7147 0.9995 1419149 ChemDiv1_006580 Cc1c(NC(=O)CC2SC(=O)NC2=O)c(=O)n(c3ccccc3)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L03 compound treatment 283.9 96.2 0.5 283.3 96.6 0.5 0.7099 1.0 1162869 ChemDiv1_006581 COC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(OCc3ccc(F)cc3)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L04 compound treatment 281.7 94.0 0.49 278.9 92.2 0.48 0.6856 0.9999 1718793 ChemDiv1_006582 O=C(CC1SC(=O)NC1=O)Nc2ccc(NC(=O)CC3SC(=O)NC3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L05 compound treatment 285.4 97.7 0.51 280.0 93.3 0.48 0.7033 0.9997 1252646 ChemDiv1_006583 CCOc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L06 compound treatment 281.2 93.5 0.49 281.0 94.3 0.49 0.6915 1.0 1278265 ChemDiv1_006584 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L07 compound treatment 278.9 91.2 0.48 278.7 92.0 0.48 0.6745 1.0 1740380 ChemDiv1_006585 Cc1nnc(Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L08 compound treatment 281.6 93.9 0.49 282.1 95.4 0.5 0.697 1.0 1394819 ChemDiv1_006586 COc1ccc(cc1COc2cccc(C)c2C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L09 compound treatment 282.1 94.4 0.49 282.6 95.9 0.5 0.7007 1.0 1973360 ChemDiv1_006587 COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2C)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L10 compound treatment 280.6 92.9 0.48 276.0 89.3 0.46 0.6709 0.9998 1259021 ChemDiv1_006588 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4cc(Br)ccc4O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L11 compound treatment 277.2 89.5 0.47 281.5 94.8 0.49 0.6786 0.9996 1973361 ChemDiv1_006589 Oc1ccc(cc1NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L12 compound treatment 278.0 90.3 0.47 277.0 90.3 0.47 0.665 1.0 1973362 ChemDiv1_006590 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(Sc5ccc(F)cc5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L13 compound treatment 282.7 95.0 0.5 278.5 91.8 0.48 0.6878 0.9998 1973363 ChemDiv1_006591 Cc1csc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L14 compound treatment 280.2 92.5 0.48 279.1 92.4 0.48 0.6808 1.0 1973364 ChemDiv1_006592 CCSc1nnc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L15 compound treatment 297.7 110.0 0.57 301.0 114.0 0.59 0.8259 0.9999 1973365 ChemDiv1_006593 OC(=O)c1ccc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)cc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L16 compound treatment 275.9 88.2 0.46 277.8 91.1 0.47 0.6602 0.9999 1973366 ChemDiv1_006594 [O-][N+](=O)c1cc(Nc2ncnc3ccccc23)cc(Oc4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L17 compound treatment 281.6 93.9 0.49 278.9 92.2 0.48 0.6852 0.9999 1973367 ChemDiv1_006595 CCOC(=O)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L18 compound treatment 282.6 94.9 0.5 283.4 96.7 0.5 0.7055 1.0 1275470 ChemDiv1_006596 Cc1cc2nc(Cc3cc4OCOc4cc3Br)c(=O)[nH]c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L19 compound treatment 283.3 95.6 0.5 280.2 93.5 0.49 0.6963 0.9999 1973368 ChemDiv1_006597 COc1ccc(cc1OC)c2c(oc3c(CN4CCC(C)CC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L20 compound treatment 293.3 106.0 0.55 293.9 107.0 0.56 0.7835 1.0 1973369 ChemDiv1_006598 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccc2C#N)c1C#N)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L21 compound treatment 284.5 96.8 0.51 288.1 101.0 0.53 0.7298 0.9998 1973370 ChemDiv1_006599 Clc1c(sc2ccccc12)C(=O)Nc3cccc(NC(=O)c4cccc(Cl)c4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L22 compound treatment 277.9 90.2 0.47 277.5 90.8 0.47 0.6664 1.0 1973371 ChemDiv1_006600 Cc1cc(Br)ccc1N2C(=O)NC(=O)/C(=C/c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L23 mock treatment 281.2 93.5 0.49 276.4 89.7 0.47 0.6746 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 L24 mock treatment 76.0 -112.0 -0.58 78.2 -109.0 -0.56 -0.8108 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M01 compound treatment 287.2 99.5 0.52 285.5 98.8 0.51 0.7302 1.0 1421506 ChemDiv1_006601 Nc1c(oc2ccc(Cl)cc12)C(=O)c3ccc(Br)s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M02 compound treatment 281.8 94.1 0.49 280.3 93.6 0.49 0.6911 1.0 1973372 ChemDiv1_006602 COc1ccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M03 compound treatment 283.7 96.0 0.5 280.4 93.7 0.49 0.6985 0.9999 1973373 ChemDiv1_006603 COc1cccc(OCCOc2ccc(/C=C/3\C(=NN(C3=O)c4ccccc4)C)cc2OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M04 compound treatment 281.5 93.8 0.49 279.2 92.5 0.48 0.686 1.0 1436560 ChemDiv1_006604 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(Cl)cc6c5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M05 compound treatment 281.9 94.2 0.49 279.4 92.7 0.48 0.6882 1.0 1973374 ChemDiv1_006605 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCCOc5ccc(C)c(C)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M06 compound treatment 278.8 91.1 0.48 282.4 95.7 0.5 0.6878 0.9997 1973375 ChemDiv1_006606 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(C)n(c3C)c4ccccc4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M07 compound treatment 281.3 93.6 0.49 276.5 89.8 0.47 0.6753 0.9997 1973376 ChemDiv1_006607 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M08 compound treatment 278.4 90.7 0.47 276.9 90.2 0.47 0.6661 1.0 1535909 ChemDiv1_006608 CC1CN(CC(C)O1)C(=O)c2ccccc2C(=O)Nc3ccc4nc(SCC(=O)NC5CCCCC5)sc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M09 compound treatment 282.8 95.1 0.5 278.8 92.1 0.48 0.6893 0.9998 1608336 ChemDiv1_006609 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(OCC)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M10 compound treatment 281.4 93.7 0.49 281.5 94.8 0.49 0.6941 1.0 1973377 ChemDiv1_006610 CC/N=C/1\S/C(=C\c2ccc(Oc3ccc(cc3C#N)[N+](=O)[O-])c(OC)c2)/C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M11 compound treatment 279.1 91.4 0.48 281.9 95.2 0.49 0.687 0.9998 1683305 ChemDiv1_006611 CC(Sc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3cc4OCOc4cc3Cl)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M12 compound treatment 283.5 95.8 0.5 282.2 95.5 0.5 0.7044 1.0 1973378 ChemDiv1_006612 Fc1ccc(/C=C/2\Sc3ccccc3C2=O)c(F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M13 compound treatment 282.3 94.6 0.49 280.9 94.2 0.49 0.6952 1.0 1973379 ChemDiv1_006613 Brc1cc2OCOc2cc1/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M14 compound treatment 280.0 92.3 0.48 277.6 90.9 0.47 0.6746 1.0 1250123 ChemDiv1_006614 COc1ccc(cc1OC)c2nc3cc(NC(=O)c4sc5ccccc5c4Cl)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M15 compound treatment 282.0 94.3 0.49 279.0 92.3 0.48 0.6871 0.9999 1558251 ChemDiv1_006615 CC1CCCN(C1)c2nc3nonc3nc2N4CCCC(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M16 compound treatment 276.2 88.5 0.46 279.4 92.7 0.48 0.6672 0.9998 1646831 ChemDiv1_006616 CSc1ncnc2ncn(CC(=O)Nc3ccc(C)c(C)c3)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M17 compound treatment 374.0 186.0 0.97 367.7 181.0 0.94 1.3525 0.9999 1949593 ChemDiv1_006617 COc1cc(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M18 compound treatment 287.4 99.7 0.52 283.5 96.8 0.5 0.7235 0.9999 1973380 ChemDiv1_006618 CCCOc1c(Br)cc(Br)cc1/C=C/2\NC(=S)NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M19 compound treatment 400.0 212.0 1.11 400.4 214.0 1.11 1.5686 1.0 1467041 ChemDiv1_006619 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)c(Br)cc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M20 compound treatment 277.8 90.1 0.47 278.1 91.4 0.48 0.6683 1.0 1244793 ChemDiv1_006620 Clc1ccccc1NC(=O)CSc2nc3ccccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M21 compound treatment 278.0 90.3 0.47 269.9 83.2 0.43 0.6389 0.9991 1738272 ChemDiv1_006621 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2Cl)C(=O)Nc3ccc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M22 compound treatment 279.9 92.2 0.48 277.6 90.9 0.47 0.6742 1.0 1665628 ChemDiv1_006622 COc1ccc2[nH]c(SCC(=O)Nc3ccc(NC(=O)C)cc3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M23 mock treatment 279.8 92.1 0.48 280.6 93.9 0.49 0.6849 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 M24 mock treatment 190.9 3.22 0.02 187.2 0.481 0.0 0.0136 0.8037 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N01 compound treatment 290.1 102.0 0.53 283.5 96.8 0.5 0.7335 0.9995 1588898 ChemDiv1_006623 OC(=O)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)cc(NC(=O)CSc4nc5ccccc5[nH]4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N02 compound treatment 280.8 93.1 0.49 277.2 90.5 0.47 0.676 0.9999 1639393 ChemDiv1_006624 Cc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N03 compound treatment 282.7 95.0 0.5 290.3 104.0 0.54 0.7312 0.9991 1331567 ChemDiv1_006625 COC(=O)C1=C(C)OC(=C(C#N)C1c2cc(OC)ccc2OC)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N04 compound treatment 279.0 91.3 0.48 279.1 92.4 0.48 0.6764 1.0 1401807 ChemDiv1_006626 CCOC(=O)c1[nH]c2c(OC)cc(OC)cc2c1CCN3C(=O)c4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N05 compound treatment 275.6 87.9 0.46 281.7 95.0 0.49 0.6734 0.9993 1973381 ChemDiv1_006627 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N06 compound treatment 282.3 94.6 0.49 280.1 93.4 0.49 0.6922 1.0 1315230 ChemDiv1_006628 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N07 compound treatment 278.0 90.3 0.47 279.4 92.7 0.48 0.6738 0.9999 1231439 ChemDiv1_006629 O=S(=O)(Nc1nccs1)c2ccc(Nc3nnc(c4ccccc4)c5ccccc35)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N08 compound treatment 289.3 102.0 0.53 281.4 94.7 0.49 0.7228 0.9993 1317640 ChemDiv1_006630 COc1ccc(cc1COc2c(C)cccc2C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N09 compound treatment 279.6 91.9 0.48 278.9 92.2 0.48 0.6779 1.0 1973382 ChemDiv1_006631 COCc1cc(C)nc(SCC(=O)Nc2ccc(C)c(C)c2)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N10 compound treatment 276.6 88.9 0.46 276.1 89.4 0.46 0.6565 1.0 1973383 ChemDiv1_006632 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4cccc([N+](=O)[O-])c4O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N11 compound treatment 279.6 91.9 0.48 278.3 91.6 0.48 0.6757 1.0 1973384 ChemDiv1_006633 Oc1cc(ccc1NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N12 compound treatment 279.8 92.1 0.48 281.5 94.8 0.49 0.6882 0.9999 1973385 ChemDiv1_006634 Fc1ccc(cc1CNC(=O)Cn2c3ccccc3c(=O)c4ccccc24)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N13 compound treatment 280.0 92.3 0.48 282.9 96.2 0.5 0.694 0.9998 1973386 ChemDiv1_006635 CCc1nnc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N14 compound treatment 285.4 97.7 0.51 276.9 90.2 0.47 0.6919 0.9991 1973387 ChemDiv1_006636 O=C(Cn1c2ccccc2c(=O)c3ccccc13)Nc4ccc(Oc5ccc6C(=O)N(Cc7ccco7)C(=O)c6c5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N15 compound treatment 308.2 121.0 0.63 318.7 132.0 0.69 0.9297 0.999 1973388 ChemDiv1_006637 OC(=O)c1cc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N16 compound treatment 282.4 94.7 0.49 273.5 86.8 0.45 0.6683 0.999 1429793 ChemDiv1_006638 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cc(Br)cs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N17 compound treatment 278.4 90.7 0.47 279.3 92.6 0.48 0.6749 1.0 1973389 ChemDiv1_006639 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)c4cccnc4)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N18 compound treatment 281.8 94.1 0.49 278.4 91.7 0.48 0.6841 0.9999 1120541 ChemDiv1_006640 Brc1cc2OCOc2cc1Cc3nc4ccccc4[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N19 compound treatment 274.1 86.4 0.45 276.6 89.9 0.47 0.6491 0.9998 1973390 ChemDiv1_006641 COc1ccc(cc1OC)c2c(oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N20 compound treatment 273.2 85.5 0.45 278.8 92.1 0.48 0.6539 0.9994 1210544 ChemDiv1_006642 O=C(CSc1nc2CCCCc2cc1C#N)Nc3ccccc3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N21 compound treatment 285.4 97.7 0.51 279.5 92.8 0.48 0.7015 0.9996 1324593 ChemDiv1_006643 Cc1cc2nc(oc2cc1C)c3cc(NC(=O)c4sc5ccccc5c4Cl)ccc3O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N22 compound treatment 277.0 89.3 0.47 277.8 91.1 0.47 0.6642 1.0 1973391 ChemDiv1_006644 Fc1ccccc1N2C(=O)NC(=O)/C(=C\c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N23 mock treatment 279.2 91.5 0.48 277.6 90.9 0.47 0.6716 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 N24 mock treatment 193.7 6.02 0.03 185.5 -1.22 -0.01 0.0177 0.5532 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O01 compound treatment 280.3 92.6 0.48 281.8 95.1 0.49 0.6911 0.9999 1973392 ChemDiv1_006645 CCOC(=O)c1nnn(c1CSc2nc3ccccc3s2)c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O02 compound treatment 284.2 96.5 0.5 281.8 95.1 0.49 0.7055 1.0 1301014 ChemDiv1_006646 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2Cl)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O03 compound treatment 278.6 90.9 0.47 278.0 91.3 0.47 0.6709 1.0 1973393 ChemDiv1_006647 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCCOc5cccc(C)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O04 compound treatment 282.1 94.4 0.49 276.3 89.6 0.47 0.6775 0.9996 1137863 ChemDiv1_006648 Fc1ccc(cc1Br)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O05 compound treatment 284.5 96.8 0.51 279.5 92.8 0.48 0.6981 0.9997 1973394 ChemDiv1_006649 COc1ccccc1OCCOc2ccc(cc2/C=C/3\C(=NN(C3=O)c4ccccc4)C)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O06 compound treatment 284.2 96.5 0.5 272.2 85.5 0.44 0.6702 0.9981 1973395 ChemDiv1_006650 COC(=O)c1ccc(cc1)n2c(C)cc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccc(OC)cc4)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O07 compound treatment 283.1 95.4 0.5 284.0 97.3 0.51 0.7095 1.0 1973396 ChemDiv1_006651 [O-][N+](=O)c1cc2OCOc2cc1C3Nc4ccc(cc4NC5=C3C(=O)CCC5)C(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O08 compound treatment 279.6 91.9 0.48 277.9 91.2 0.47 0.6742 1.0 1945737 ChemDiv1_006652 O=C1C2CCCCC2C(=O)N1c3ccc4[nH]c(=S)sc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O09 compound treatment 277.4 89.7 0.47 276.9 90.2 0.47 0.6624 1.0 1342490 ChemDiv1_006653 Cc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2c1C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O10 compound treatment 280.7 93.0 0.49 278.2 91.5 0.48 0.6794 0.9999 1973397 ChemDiv1_006654 COc1cc(/C=C/2\S/C(=N\C)/N(C)C2=O)ccc1Oc3ccc(cc3C#N)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O11 compound treatment 295.2 108.0 0.56 296.0 109.0 0.57 0.7983 1.0 1973398 ChemDiv1_006655 CCOc1cc(/C=C/2\S\C(=N\C)\N(C)C2=O)cc(Cl)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O12 compound treatment 281.0 93.3 0.49 283.4 96.7 0.5 0.6996 0.9999 1973399 ChemDiv1_006656 C/N=C/1\S/C(=C\c2ccc(o2)c3cc(Cl)ccc3[N+](=O)[O-])/C(=O)N1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O13 compound treatment 284.8 97.1 0.51 291.7 105.0 0.55 0.7441 0.9993 1923956 ChemDiv1_006657 Cc1ccsc1/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O14 compound treatment 279.6 91.9 0.48 277.5 90.8 0.47 0.6727 1.0 1973400 ChemDiv1_006658 [O-][N+](=O)c1cc(ccc1N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O15 compound treatment 287.4 99.7 0.52 279.1 92.4 0.48 0.7074 0.9992 1973401 ChemDiv1_006659 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3cc(Cl)ccc3[N+](=O)[O-])\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O16 compound treatment 279.0 91.3 0.48 278.2 91.5 0.48 0.6731 1.0 1400774 ChemDiv1_006660 Cn1c(Sc2ncnn2Cc3ccccc3)nc4n(C)c(=O)n(C)c(=O)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O17 compound treatment 297.2 110.0 0.57 298.7 112.0 0.58 0.8156 1.0 1926143 ChemDiv1_006661 OC(=O)c1cccc(c1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O18 compound treatment 277.3 89.6 0.47 280.1 93.4 0.49 0.6738 0.9998 1973402 ChemDiv1_006662 CCOc1cc(/C=C/2\NC(=S)NC2=O)cc(Br)c1OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O19 compound treatment 287.5 99.8 0.52 284.5 97.8 0.51 0.7276 0.9999 1973403 ChemDiv1_006663 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(Br)c1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O20 compound treatment 282.0 94.3 0.49 282.1 95.4 0.5 0.6985 1.0 1253659 ChemDiv1_006664 OC(=O)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)ccc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O21 compound treatment 274.4 86.7 0.45 275.7 89.0 0.46 0.6469 0.9999 1494268 ChemDiv1_006665 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2C)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O22 compound treatment 283.9 96.2 0.5 279.5 92.8 0.48 0.6959 0.9998 1257969 ChemDiv1_006666 COc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)c(c3)C(=O)O)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O23 mock treatment 283.7 96.0 0.5 279.6 92.9 0.48 0.6956 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 O24 mock treatment 97.4 -90.3 -0.47 94.8 -91.9 -0.48 -0.6709 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P01 compound treatment 278.8 91.1 0.48 282.9 96.2 0.5 0.6896 0.9997 1249048 ChemDiv1_006667 COc1ccc2[nH]c(SCC(=O)Nc3cc(NC(=O)CSc4nc5cc(OC)ccc5[nH]4)cc(c3)C(=O)O)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P02 compound treatment 282.6 94.9 0.5 284.5 97.8 0.51 0.7095 0.9999 1505672 ChemDiv1_006668 Cc1ccc(NC(=O)CC2SC(=O)NC2=O)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P03 compound treatment 283.2 95.5 0.5 289.3 103.0 0.53 0.7294 0.9994 1973404 ChemDiv1_006669 COC(=O)C1=C(C)OC(=C(C#N)C1c2c(F)c(F)c(F)c(F)c2F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P04 compound treatment 282.9 95.2 0.5 279.5 92.8 0.48 0.6922 0.9999 1601984 ChemDiv1_006670 COc1ccc(cc1CN2CCOCC2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P05 compound treatment 279.7 92.0 0.48 275.4 88.7 0.46 0.6654 0.9998 1552457 ChemDiv1_006671 CCC(C)Nc1nc(NC(C)C)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P06 compound treatment 281.2 93.5 0.49 277.5 90.8 0.47 0.6786 0.9999 1228047 ChemDiv1_006672 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P07 compound treatment 283.7 96.0 0.5 278.8 92.1 0.48 0.6926 0.9997 1267312 ChemDiv1_006673 Cc1ccc(cc1)c2nnc(Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P08 compound treatment 282.0 94.3 0.49 282.2 95.5 0.5 0.6988 1.0 1926800 ChemDiv1_006674 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc(cc4)[N+](=O)[O-])c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P09 compound treatment 278.4 90.7 0.47 278.5 91.8 0.48 0.672 1.0 1973405 ChemDiv1_006675 COCc1cc(C)nc(SCC(=O)Nc2ccccc2OC)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P10 compound treatment 278.9 91.2 0.48 277.9 91.2 0.47 0.6716 1.0 1973406 ChemDiv1_006676 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4ccc(OC(F)F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P11 compound treatment 284.1 96.4 0.5 281.3 94.6 0.49 0.7033 0.9999 1973407 ChemDiv1_006677 CCC1CCCCN1C(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P12 compound treatment 276.9 89.2 0.47 285.5 98.8 0.51 0.6922 0.9988 1973408 ChemDiv1_006678 CCOC(=O)N1CCC(CC1)NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P13 compound treatment 279.6 91.9 0.48 279.8 93.1 0.48 0.6812 1.0 1973409 ChemDiv1_006679 CCCCc1nnc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P14 compound treatment 279.2 91.5 0.48 279.9 93.2 0.48 0.6801 1.0 1973410 ChemDiv1_006680 CCOC(=O)c1sc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P15 compound treatment 278.9 91.2 0.48 278.2 91.5 0.48 0.6727 1.0 1973411 ChemDiv1_006681 COC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P16 compound treatment 277.7 90.0 0.47 281.5 94.8 0.49 0.6804 0.9997 1973412 ChemDiv1_006682 COc1ccccc1Oc2ccc(cc2NC(=O)Cn3c4ccccc4c(=O)c5ccccc35)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P17 compound treatment 280.5 92.8 0.48 281.8 95.1 0.49 0.6918 0.9999 1973413 ChemDiv1_006683 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P18 compound treatment 281.5 93.8 0.49 280.1 93.4 0.49 0.6893 1.0 1973414 ChemDiv1_006684 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3C(C)CC(N(C(=O)c4cccc(c4)[N+](=O)[O-])c5ccccc5)c6ccccc36 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P19 compound treatment 282.9 95.2 0.5 279.7 93.0 0.48 0.693 0.9999 1973415 ChemDiv1_006685 CCN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(OC)c(OC)c4)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P20 compound treatment 279.4 91.7 0.48 282.8 96.1 0.5 0.6915 0.9998 1973416 ChemDiv1_006686 O=C(CSc1nc2CCCCCc2cc1C#N)Nc3ccccc3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P21 compound treatment 282.7 95.0 0.5 285.3 98.6 0.51 0.7128 0.9999 1186170 ChemDiv1_006687 Cc1ccc(cc1NC(=O)c2sc3ccccc3c2Cl)c4nc5cc(Cl)ccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P22 compound treatment 286.4 98.7 0.51 282.3 95.6 0.5 0.7154 0.9998 1973417 ChemDiv1_006688 Fc1ccc(cc1)c2ccc(/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P23 mock treatment 278.1 90.4 0.47 283.3 96.6 0.5 0.6885 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.605 P24 mock treatment 100.5 -87.2 -0.45 97.4 -89.3 -0.46 -0.6499 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A01 compound treatment 289.9 101.0 0.53 289.9 104.0 0.54 0.7547 1.0 1973418 ChemDiv1_006689 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)ccc1OCc5ccc(cc5)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A02 compound treatment 288.6 100.0 0.52 286.8 100.0 0.52 0.7385 1.0 1928687 ChemDiv1_006690 O=C(CCN1C(=O)/C(=C/c2cccs2)/SC1=S)Nc3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A03 compound treatment 282.4 94.0 0.49 282.2 95.8 0.5 0.6988 1.0 1973419 ChemDiv1_006691 CCN(CC)c1cc(Nc2ccc(cc2)c3ccccc3)c([N+](=O)[O-])c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A04 compound treatment 332.5 144.0 0.75 326.4 140.0 0.73 1.046 0.9999 1973420 ChemDiv1_006692 Brc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A05 compound treatment 276.8 88.3 0.46 277.3 90.9 0.47 0.6601 0.9999 1973421 ChemDiv1_006693 CCN(CC)c1cc(Nc2ccc(Cl)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A06 compound treatment 282.2 93.8 0.49 285.9 99.5 0.52 0.7116 0.9996 1973422 ChemDiv1_006694 CN1C(=O)C(=Cc2cc(C)n(c2C)c3ccc(cc3C)[N+](=O)[O-])C(=O)N(C)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A07 compound treatment 280.1 91.7 0.48 283.5 97.1 0.5 0.6951 0.9996 1973423 ChemDiv1_006695 COc1ccccc1Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A08 compound treatment 267.0 78.5 0.41 263.1 76.7 0.4 0.5718 0.9999 1973424 ChemDiv1_006696 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A09 compound treatment 275.4 87.0 0.45 279.3 92.9 0.48 0.6623 0.9995 1973425 ChemDiv1_006697 COc1ccccc1Nc2cc(N(C)C)c3nonc3c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A10 compound treatment 259.2 70.8 0.37 243.5 57.1 0.3 0.4709 0.9942 1973426 ChemDiv1_006698 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OC(=O)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A11 compound treatment 278.8 90.3 0.47 278.2 91.8 0.48 0.6708 1.0 1973427 ChemDiv1_006699 COc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A12 compound treatment 280.0 91.5 0.48 280.6 94.2 0.49 0.684 0.9999 1973428 ChemDiv1_006700 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OC(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A13 compound treatment 279.6 91.2 0.48 277.0 90.6 0.47 0.6693 1.0 1973429 ChemDiv1_006701 [O-][N+](=O)c1c(Nc2ccc(cc2)c3ccccc3)cc(N4CCOCC4)c5nonc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A14 compound treatment 277.3 88.8 0.46 276.6 90.2 0.47 0.6594 1.0 1502754 ChemDiv1_006702 COC(=O)c1ccc(CSc2nc(N3CCOCC3)c4COC(C)(C)Cc4c2C#N)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A15 compound treatment 279.3 90.8 0.47 277.2 90.8 0.47 0.669 1.0 1973430 ChemDiv1_006703 [O-][N+](=O)c1c(Nc2ccc(Cl)cc2)cc(N3CCOCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A16 compound treatment 279.0 90.5 0.47 274.6 88.2 0.46 0.6583 0.9999 1973431 ChemDiv1_006704 Oc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)cc1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A17 compound treatment 280.0 91.5 0.48 280.4 94.0 0.49 0.6833 0.9999 1518178 ChemDiv1_006705 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2Cl)C(=O)Nc3ccccc3OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A18 compound treatment 279.0 90.5 0.47 279.3 92.9 0.48 0.6756 0.9999 1973432 ChemDiv1_006706 CCOC(=O)Cn1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A19 compound treatment 278.1 89.7 0.47 276.5 90.1 0.47 0.662 1.0 1973433 ChemDiv1_006707 CCOC(=O)C1=CN(C=C(C1c2cc(Br)ccc2OC)C(=O)OCC)c3ccc(OCC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A20 compound treatment 281.9 93.5 0.49 281.5 95.1 0.49 0.6943 1.0 1973434 ChemDiv1_006708 CCOc1ccc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3)c(OCC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A21 compound treatment 276.7 88.3 0.46 278.6 92.2 0.48 0.6645 0.9998 1973435 ChemDiv1_006709 COc1cc(/C=C\2/SC(=S)N(CCC(=O)N3CCN(C)CC3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A22 compound treatment 281.0 92.5 0.48 276.6 90.2 0.47 0.673 0.9999 1973436 ChemDiv1_006710 Cn1c2ccccc2c3nnc(SCC(=O)Nc4nc5ccc(cc5s4)[N+](=O)[O-])nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A23 mock treatment 280.1 91.7 0.48 278.5 92.1 0.48 0.6767 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 A24 mock treatment 82.1 -106.0 -0.55 80.4 -106.0 -0.55 -0.7818 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B01 compound treatment 285.8 97.3 0.51 290.1 104.0 0.54 0.7403 0.9996 1973437 ChemDiv1_006711 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B02 compound treatment 281.4 93.0 0.48 282.5 96.1 0.5 0.6962 0.9999 1233873 ChemDiv1_006712 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B03 compound treatment 291.9 103.0 0.54 287.4 101.0 0.53 0.7529 0.9999 1973438 ChemDiv1_006713 Brc1ccc(cc1)N2C(=O)/C(=C/c3cccn3c4ccccc4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B04 compound treatment 279.5 91.0 0.47 282.9 96.5 0.5 0.6906 0.9996 1605926 ChemDiv1_006714 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B05 compound treatment 283.1 94.7 0.49 282.3 95.9 0.5 0.7017 1.0 1973439 ChemDiv1_006715 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OC(C)C(=O)O)cc3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B06 compound treatment 277.6 89.2 0.47 281.7 95.3 0.5 0.6792 0.9995 1700200 ChemDiv1_006716 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Br)c3)C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B07 compound treatment 189.2 0.75 0.0 190.6 4.22 0.02 0.0183 0.8202 1973440 ChemDiv1_006717 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc(CC=C)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B08 compound treatment 281.0 92.5 0.48 276.1 89.7 0.47 0.6712 0.9999 1548058 ChemDiv1_006718 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3Cl)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B09 compound treatment 278.4 90.0 0.47 280.3 93.9 0.49 0.677 0.9998 1973441 ChemDiv1_006719 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3C)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B10 compound treatment 279.3 90.8 0.47 282.1 95.7 0.5 0.687 0.9997 1267439 ChemDiv1_006720 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Cl)cc3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B11 compound treatment 275.7 87.3 0.46 283.0 96.6 0.5 0.677 0.9988 1973442 ChemDiv1_006721 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(F)c3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B12 compound treatment 276.5 88.0 0.46 278.3 91.9 0.48 0.6627 0.9998 1469298 ChemDiv1_006722 COc1ccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B13 compound treatment 279.2 90.8 0.47 278.1 91.7 0.48 0.6719 1.0 1219279 ChemDiv1_006723 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B14 compound treatment 275.1 86.7 0.45 273.8 87.4 0.45 0.641 1.0 1714214 ChemDiv1_006724 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B15 compound treatment 276.3 87.8 0.46 278.6 92.2 0.48 0.663 0.9997 1511300 ChemDiv1_006725 CCOc1ccc(NC(=O)C(C)CSc2nc3ccc(NC(=O)CC)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B16 compound treatment 269.5 81.0 0.42 272.2 85.8 0.45 0.6144 0.9996 1608255 ChemDiv1_006726 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Br)cc3)C(=O)Nc4cc(C)ccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B17 compound treatment 278.1 89.7 0.47 279.2 92.8 0.48 0.6719 0.9999 1973443 ChemDiv1_006727 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B18 compound treatment 277.7 89.3 0.47 273.6 87.2 0.45 0.6498 0.9999 1485444 ChemDiv1_006728 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B19 compound treatment 279.3 90.8 0.47 279.5 93.1 0.48 0.6774 0.9999 1973444 ChemDiv1_006729 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B20 compound treatment 275.6 87.2 0.45 277.7 91.3 0.47 0.6571 0.9998 1183823 ChemDiv1_006730 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5ccc(C)cn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B21 compound treatment 275.8 87.3 0.46 276.1 89.7 0.47 0.652 0.9999 1716216 ChemDiv1_006731 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc(c4ccccc4)c(n3)c5ccccc5)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B22 compound treatment 277.4 89.0 0.46 279.0 92.6 0.48 0.6686 0.9998 1973445 ChemDiv1_006732 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B23 mock treatment 278.4 90.0 0.47 277.4 91.0 0.47 0.6664 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 B24 mock treatment 79.5 -109.0 -0.57 75.0 -111.0 -0.58 -0.8112 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C01 compound treatment 286.6 98.2 0.51 283.7 97.3 0.51 0.7198 1.0 1973446 ChemDiv1_006733 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc(Br)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C02 compound treatment 309.4 121.0 0.63 298.0 112.0 0.58 0.8564 0.9991 1973447 ChemDiv1_006734 Clc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)N4CCCCC4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C03 compound treatment 284.3 95.8 0.5 285.3 98.9 0.51 0.7172 0.9999 1973448 ChemDiv1_006735 CCN(CC)c1cc(Nc2cccc(OC)c2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C04 compound treatment 368.2 180.0 0.94 355.5 169.0 0.88 1.2847 0.9995 1973449 ChemDiv1_006736 Cc1cc(Br)ccc1N2C(=O)/C(=C/c3ccc(o3)N4CCCC4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C05 compound treatment 279.7 91.3 0.48 284.7 98.3 0.51 0.698 0.9994 1973450 ChemDiv1_006737 COc1cccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C06 compound treatment 282.5 94.0 0.49 281.6 95.2 0.49 0.6969 1.0 1973451 ChemDiv1_006738 Brc1ccc(cc1)C(=O)Oc2ccc(NC3=NS(=O)(=O)c4ccccc34)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C07 compound treatment 278.9 90.5 0.47 283.0 96.6 0.5 0.6888 0.9995 1973452 ChemDiv1_006739 [O-][N+](=O)c1c(Nc2ccc(Cl)cc2)cc(N3CCCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C08 compound treatment 279.8 91.3 0.48 279.0 92.6 0.48 0.6774 1.0 1973453 ChemDiv1_006740 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OS(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C09 compound treatment 279.0 90.5 0.47 279.9 93.5 0.49 0.6778 0.9999 1973454 ChemDiv1_006741 CCNc1cc(Nc2ccc(cc2)c3ccccc3)c([N+](=O)[O-])c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C10 compound treatment 272.0 83.5 0.44 274.8 88.4 0.46 0.6332 0.9996 1973455 ChemDiv1_006742 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C11 compound treatment 273.8 85.3 0.45 274.9 88.5 0.46 0.6402 0.9999 1973456 ChemDiv1_006743 CN(c1ccccc1)c2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C12 compound treatment 277.2 88.8 0.46 280.2 93.8 0.49 0.6722 0.9997 1973457 ChemDiv1_006744 COc1ccc(/C=C/2\SC(=N)NC2=O)cc1OC(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C13 compound treatment 280.2 91.8 0.48 279.7 93.3 0.49 0.6815 1.0 1973458 ChemDiv1_006745 COc1cccc(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C14 compound treatment 278.5 90.0 0.47 277.8 91.4 0.48 0.6682 1.0 1582116 ChemDiv1_006746 CNC(=O)c1ccc(o1)c2sc3nc(N4CCOCC4)c5CCCCc5c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C15 compound treatment 280.9 92.5 0.48 277.8 91.4 0.48 0.6771 1.0 1558534 ChemDiv1_006747 Clc1cc(ccc1NC(=O)Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C16 compound treatment 279.5 91.0 0.47 277.4 91.0 0.47 0.6704 1.0 1946364 ChemDiv1_006748 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c(cc1OC)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C17 compound treatment 277.9 89.5 0.47 278.3 91.9 0.48 0.6678 0.9999 1973459 ChemDiv1_006749 CCOC(=O)C1=CN(C=C(C1c2ccc(OC)c(Br)c2)C(=O)OCC)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C18 compound treatment 280.4 92.0 0.48 278.2 91.8 0.48 0.6767 1.0 1973460 ChemDiv1_006750 COC(=O)COc1ccccc1/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C19 compound treatment 274.8 86.3 0.45 277.1 90.7 0.47 0.652 0.9997 1973461 ChemDiv1_006751 Cc1ccc(cc1)C2NC(Cc3c2[nH]c4ccccc34)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C20 compound treatment 285.9 97.5 0.51 278.5 92.1 0.48 0.6981 0.9996 1701814 ChemDiv1_006752 CC1C=C(C)CC2C1C(=O)N(C2=O)c3ccc(cc3)C(=O)Nc4ccc(NC(=O)C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C21 compound treatment 280.9 92.5 0.48 279.4 93.0 0.48 0.6829 1.0 1973462 ChemDiv1_006753 COc1cc(/C=C\2/SC(=S)N(CCC(=O)N3CCOCC3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C22 compound treatment 279.2 90.8 0.47 279.1 92.7 0.48 0.6756 1.0 1973463 ChemDiv1_006754 [O-][N+](=O)c1ccc2nc(NC(=O)CSc3nnc4c5ccccc5n(CC=C)c4n3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C23 mock treatment 281.5 93.0 0.49 278.4 92.0 0.48 0.6815 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 C24 mock treatment 76.3 -112.0 -0.59 78.1 -108.0 -0.56 -0.8117 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D01 compound treatment 295.6 107.0 0.56 288.0 102.0 0.53 0.7688 0.9996 1973464 ChemDiv1_006755 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D02 compound treatment 279.1 90.7 0.47 281.2 94.8 0.49 0.6829 0.9998 1315943 ChemDiv1_006756 COc1cccc(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D03 compound treatment 289.1 101.0 0.53 292.8 106.0 0.55 0.7624 0.9997 1973465 ChemDiv1_006757 Brc1ccc(cc1)n2cccc2/C=C/3\C(=O)NC(=S)N(C3=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D04 compound treatment 282.2 93.8 0.49 283.8 97.4 0.51 0.7039 0.9998 1432188 ChemDiv1_006758 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D05 compound treatment 286.0 97.5 0.51 287.1 101.0 0.52 0.7301 0.9999 1973466 ChemDiv1_006759 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D06 compound treatment 282.4 94.0 0.49 278.0 91.6 0.48 0.6833 0.9999 1973467 ChemDiv1_006760 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D07 compound treatment 280.7 92.3 0.48 277.0 90.6 0.47 0.6734 0.9999 1973468 ChemDiv1_006761 COc1cc(/C=C/2\C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)ccc1OCc4cccc(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D08 compound treatment 281.2 92.8 0.48 286.4 100.0 0.52 0.7098 0.9994 1852042 ChemDiv1_006762 CC1=C(C(C2=C(CCCC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D09 compound treatment 296.0 108.0 0.56 294.2 108.0 0.56 0.793 1.0 1973469 ChemDiv1_006763 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(CC=C)c(O)c(OCC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D10 compound treatment 276.9 88.5 0.46 280.1 93.7 0.49 0.6708 0.9996 1852080 ChemDiv1_006764 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D11 compound treatment 284.6 96.2 0.5 282.7 96.3 0.5 0.7087 1.0 1973470 ChemDiv1_006765 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(Br)c(o3)N4CCOCC4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D12 compound treatment 277.5 89.0 0.46 280.5 94.1 0.49 0.6744 0.9997 1630028 ChemDiv1_006766 COc1ccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D13 compound treatment 277.3 88.8 0.46 278.7 92.3 0.48 0.6671 0.9998 1491586 ChemDiv1_006767 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4F)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D14 compound treatment 279.2 90.8 0.47 282.4 96.0 0.5 0.6877 0.9996 1450622 ChemDiv1_006768 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D15 compound treatment 277.1 88.7 0.46 279.3 92.9 0.48 0.6686 0.9998 1945672 ChemDiv1_006769 COc1ccc(Cl)cc1N(CC(=O)N2CCCCCC2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D16 compound treatment 275.2 86.8 0.45 279.9 93.5 0.49 0.6638 0.9994 1852124 ChemDiv1_006770 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(c3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D17 compound treatment 279.8 91.3 0.48 275.0 88.6 0.46 0.6627 0.9999 1973471 ChemDiv1_006771 COc1ccc(cc1OC)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D18 compound treatment 280.9 92.5 0.48 280.2 93.8 0.49 0.6859 1.0 1386387 ChemDiv1_006772 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D19 compound treatment 280.6 92.2 0.48 274.5 88.1 0.46 0.6638 0.9997 1973472 ChemDiv1_006773 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D20 compound treatment 278.2 89.8 0.47 277.5 91.1 0.47 0.666 1.0 1667579 ChemDiv1_006774 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5cc(C)ccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D21 compound treatment 277.6 89.2 0.47 276.2 89.8 0.47 0.659 1.0 1494061 ChemDiv1_006775 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(c(o3)c4ccccc4)c5ccccc5)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D22 compound treatment 277.6 89.2 0.47 271.8 85.4 0.44 0.6428 0.9997 1973473 ChemDiv1_006776 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D23 mock treatment 281.0 92.5 0.48 276.0 89.6 0.47 0.6708 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 D24 mock treatment 76.7 -112.0 -0.58 81.6 -105.0 -0.54 -0.7973 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E01 compound treatment 280.9 92.5 0.48 272.7 86.3 0.45 0.6583 0.9994 1973474 ChemDiv1_006777 Cc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E02 compound treatment 375.3 187.0 0.97 359.1 173.0 0.9 1.3241 0.9992 1973475 ChemDiv1_006778 Clc1cccc(c1)N2C(=O)/C(=C/c3ccc(o3)N4CCCCC4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E03 compound treatment 278.8 90.3 0.47 281.9 95.5 0.5 0.6844 0.9997 1973476 ChemDiv1_006779 CCN(CC)c1cc(N(C)c2ccccc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E04 compound treatment 364.7 176.0 0.92 351.6 165.0 0.86 1.2574 0.9994 1973477 ChemDiv1_006780 Clc1cccc(N2C(=O)/C(=C/c3ccc(o3)N4CCCC4)/C(=O)NC2=S)c1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E05 compound treatment 280.6 92.2 0.48 277.6 91.2 0.47 0.6752 1.0 1973478 ChemDiv1_006781 CCOc1ccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E06 compound treatment 280.8 92.3 0.48 281.4 95.0 0.49 0.6899 0.9999 1973479 ChemDiv1_006782 [O-][N+](=O)c1cccc(c1)C(=O)Oc2cccc(NC3=NS(=O)(=O)c4ccccc34)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E07 compound treatment 282.1 93.7 0.49 282.2 95.8 0.5 0.6977 1.0 1973480 ChemDiv1_006783 CN(C)c1cc(Nc2ccc(cc2)c3ccccc3)c([N+](=O)[O-])c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E08 compound treatment 269.0 80.5 0.42 268.1 81.7 0.42 0.5975 1.0 1973481 ChemDiv1_006784 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E09 compound treatment 278.0 89.5 0.47 278.3 91.9 0.48 0.6682 0.9999 1973482 ChemDiv1_006785 CCNc1cc(Nc2ccc(OC)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E10 compound treatment 277.1 88.7 0.46 276.9 90.5 0.47 0.6597 1.0 1973483 ChemDiv1_006786 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E11 compound treatment 279.1 90.7 0.47 277.8 91.4 0.48 0.6704 1.0 1973484 ChemDiv1_006787 [O-][N+](=O)c1c(Nc2ccc(SC#N)cc2)cc(N3CCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E12 compound treatment 294.2 106.0 0.55 304.5 118.0 0.61 0.8243 0.9986 1973485 ChemDiv1_006788 COc1ccc(cc1)C(=O)Oc2c(Cl)cc(/C=C/3\SC(=N)NC3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E13 compound treatment 283.5 95.0 0.5 279.2 92.8 0.48 0.6918 0.9999 1973486 ChemDiv1_006789 COc1ccc(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E14 compound treatment 275.8 87.3 0.46 279.0 92.6 0.48 0.6627 0.9996 1973487 ChemDiv1_006790 Cc1ccccc1n2c(=O)c3c4CCCCc4sc3n5c(SCC(=O)N)nnc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E15 compound treatment 329.2 141.0 0.73 320.6 134.0 0.7 1.0125 0.9997 1601464 ChemDiv1_006791 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E16 compound treatment 277.7 89.3 0.47 277.9 91.5 0.48 0.6656 0.9999 1973488 ChemDiv1_006792 COc1cc(OC)c(cc1/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E17 compound treatment 285.1 96.7 0.5 281.2 94.8 0.49 0.705 0.9999 1250417 ChemDiv1_006793 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccccc3OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E18 compound treatment 282.4 94.0 0.49 278.9 92.5 0.48 0.6866 1.0 1973489 ChemDiv1_006794 COc1cccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E19 compound treatment 282.2 93.8 0.49 278.0 91.6 0.48 0.6826 0.9999 1131798 ChemDiv1_006795 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCOCC4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E20 compound treatment 275.4 87.0 0.45 275.4 89.0 0.46 0.6479 0.9999 1973490 ChemDiv1_006796 CN1CCN(CC1)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)cc2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E21 compound treatment 291.0 103.0 0.53 287.2 101.0 0.52 0.7489 0.9999 1973491 ChemDiv1_006797 COc1cc(/C=C\2/SC(=S)N(CCC(=O)NC3=NCCS3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E22 compound treatment 279.5 91.0 0.47 278.5 92.1 0.48 0.6745 1.0 1973492 ChemDiv1_006798 [O-][N+](=O)c1ccc(Nc2csc(NC(=O)CSc3nnc4c5ccccc5n(CC=C)c4n3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E23 mock treatment 278.5 90.0 0.47 282.0 95.6 0.5 0.6836 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 E24 mock treatment 83.4 -105.0 -0.55 76.1 -110.0 -0.57 -0.7928 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F01 compound treatment 280.1 91.7 0.48 286.7 100.0 0.52 0.7068 0.9991 1973493 ChemDiv1_006799 CN1C(=O)N(C)C(=O)C(=Cc2cc(C)n(c2C)c3cc(cc(c3)C(=O)O)C(=O)O)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F02 compound treatment 279.6 91.2 0.48 284.8 98.4 0.51 0.698 0.9993 1555897 ChemDiv1_006800 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F03 compound treatment 284.6 96.2 0.5 287.3 101.0 0.52 0.7256 0.9997 1973494 ChemDiv1_006801 COc1ccc(cc1)N2C(=O)/C(=C/c3cccn3c4ccc(Cl)cc4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F04 compound treatment 281.0 92.5 0.48 279.4 93.0 0.48 0.6833 1.0 1201108 ChemDiv1_006802 COc1cccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F05 compound treatment 315.3 127.0 0.66 316.0 130.0 0.67 0.9444 1.0 1973495 ChemDiv1_006803 Clc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F06 compound treatment 280.0 91.5 0.48 281.6 95.2 0.49 0.6877 0.9998 1973496 ChemDiv1_006804 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F07 compound treatment 276.2 87.8 0.46 280.6 94.2 0.49 0.67 0.9994 1973497 ChemDiv1_006805 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OC(C)C(=O)O)cc3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F08 compound treatment 280.3 91.8 0.48 282.3 95.9 0.5 0.6914 0.9998 1852048 ChemDiv1_006806 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F09 compound treatment 275.1 86.7 0.45 279.0 92.6 0.48 0.6601 0.9995 1973498 ChemDiv1_006807 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OC(C)C(=O)O)cc3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F10 compound treatment 282.1 93.7 0.49 282.2 95.8 0.5 0.6977 1.0 1852087 ChemDiv1_006808 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F11 compound treatment 277.1 88.7 0.46 277.6 91.2 0.47 0.6623 0.9999 1973499 ChemDiv1_006809 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3F)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F12 compound treatment 278.9 90.5 0.47 283.9 97.5 0.51 0.6921 0.9994 1376959 ChemDiv1_006810 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F13 compound treatment 282.3 93.8 0.49 277.5 91.1 0.47 0.6811 0.9999 1727847 ChemDiv1_006811 Cn1cnnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4F)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F14 compound treatment 274.5 86.0 0.45 278.5 92.1 0.48 0.656 0.9995 1520173 ChemDiv1_006812 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(C)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F15 compound treatment 281.0 92.5 0.48 279.8 93.4 0.49 0.6848 1.0 1227554 ChemDiv1_006813 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F16 compound treatment 277.0 88.5 0.46 276.2 89.8 0.47 0.6568 1.0 1852128 ChemDiv1_006814 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(c3)[N+](=O)[O-])C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F17 compound treatment 281.1 92.7 0.48 276.1 89.7 0.47 0.6715 0.9998 1973500 ChemDiv1_006815 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F18 compound treatment 279.7 91.3 0.48 276.6 90.2 0.47 0.6682 1.0 1438640 ChemDiv1_006816 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5ccc(Br)cn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F19 compound treatment 286.6 98.2 0.51 286.7 100.0 0.52 0.7308 1.0 1615288 ChemDiv1_006817 CCOC(=O)COc1ccc(C=c2sc3=NC(=C(C(c4cccs4)n3c2=O)C(=O)OCC)C)cc1OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F20 compound treatment 279.5 91.0 0.47 280.6 94.2 0.49 0.6822 0.9999 1652150 ChemDiv1_006818 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F21 compound treatment 278.0 89.5 0.47 274.6 88.2 0.46 0.6546 1.0 1350182 ChemDiv1_006819 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc(N)s3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F22 compound treatment 280.7 92.3 0.48 279.1 92.7 0.48 0.6811 1.0 1973501 ChemDiv1_006820 COC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F23 mock treatment 280.3 91.8 0.48 280.9 94.5 0.49 0.6862 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 F24 mock treatment 82.4 -106.0 -0.55 81.2 -105.0 -0.55 -0.7778 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G01 compound treatment 284.7 96.3 0.5 283.7 97.3 0.51 0.7128 1.0 1554461 ChemDiv1_006821 O=S(=O)(N1CCCCCC1)c2cccc3nonc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G02 compound treatment 382.2 194.0 1.01 375.0 189.0 0.98 1.408 0.9999 1973502 ChemDiv1_006822 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G03 compound treatment 284.1 95.7 0.5 284.8 98.4 0.51 0.7146 0.9999 1973503 ChemDiv1_006823 CCN(CC)c1cc(Nc2ccc(SC#N)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G04 compound treatment 280.5 92.0 0.48 284.5 98.1 0.51 0.7002 0.9995 1973504 ChemDiv1_006824 Fc1ccccc1N2C(=O)/C(=C/c3cn(CC(=O)Nc4ccccc4)c5ccccc35)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G05 compound treatment 282.3 93.8 0.49 282.3 95.9 0.5 0.6988 1.0 1973505 ChemDiv1_006825 COc1ccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G06 compound treatment 280.6 92.2 0.48 283.7 97.3 0.51 0.6976 0.9997 1973506 ChemDiv1_006826 [O-][N+](=O)c1cccc(c1)C(=O)Oc2ccccc2NC3=NS(=O)(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G07 compound treatment 280.3 91.8 0.48 281.5 95.1 0.49 0.6884 0.9999 1973507 ChemDiv1_006827 CCOc1ccc(Nc2cc(N(C)C)c3nonc3c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G08 compound treatment 267.7 79.3 0.41 267.4 81.0 0.42 0.5901 1.0 1973508 ChemDiv1_006828 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G09 compound treatment 282.3 93.8 0.49 282.2 95.8 0.5 0.6984 1.0 1973509 ChemDiv1_006829 CCNc1cc(Nc2ccc(C)c(Cl)c2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G10 compound treatment 288.1 99.7 0.52 286.5 100.0 0.52 0.7356 1.0 1973510 ChemDiv1_006830 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OCc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G11 compound treatment 281.6 93.2 0.49 280.7 94.3 0.49 0.6903 1.0 1973511 ChemDiv1_006831 CCN(c1ccccc1)c2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G12 compound treatment 302.3 114.0 0.59 312.0 126.0 0.65 0.8817 0.9989 1973512 ChemDiv1_006832 CCOc1cc(/C=C/2\SC(=N)NC2=O)cc(Cl)c1OC(=O)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G13 compound treatment 279.8 91.3 0.48 280.6 94.2 0.49 0.6833 0.9999 1973513 ChemDiv1_006833 CN(c1ccccc1)c2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G14 compound treatment 279.2 90.8 0.47 282.6 96.2 0.5 0.6884 0.9996 1973514 ChemDiv1_006834 O=C1C2C(C3CCC2C=C3)C(=O)N1c4nccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G15 compound treatment 227.7 39.3 0.2 211.4 25.0 0.13 0.2368 0.976 1973515 ChemDiv1_006835 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4cn(CC#N)c5ccccc45)c(=O)n23)C(=O)Nc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G16 compound treatment 270.6 82.2 0.43 271.9 85.5 0.44 0.6174 0.9998 1945940 ChemDiv1_006836 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G17 compound treatment 278.1 89.7 0.47 278.8 92.4 0.48 0.6704 0.9999 1935926 ChemDiv1_006837 CCOC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OCC)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G18 compound treatment 279.4 91.0 0.47 282.4 96.0 0.5 0.6884 0.9997 1973516 ChemDiv1_006838 COc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G19 compound treatment 281.6 93.2 0.49 277.7 91.3 0.47 0.6793 0.9999 1940449 ChemDiv1_006839 O=C(CC1S/C(=N\c2ccccc2)/N(C1=O)c3ccccc3)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G20 compound treatment 276.3 87.8 0.46 281.3 94.9 0.49 0.673 0.9993 1951238 ChemDiv1_006840 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)[N+](=O)[O-])c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G21 compound treatment 281.1 92.7 0.48 285.1 98.7 0.51 0.7046 0.9996 1927911 ChemDiv1_006841 COc1cc(/C=C\2/SC(=S)N(CCC(=O)Nc3nnc(C)s3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G22 compound treatment 273.5 85.0 0.44 277.2 90.8 0.47 0.6476 0.9995 1678680 ChemDiv1_006842 CCC(Sc1nc2ccccc2s1)C(=O)Nc3ccc(cc3)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G23 mock treatment 281.0 92.5 0.48 280.5 94.1 0.49 0.6874 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 G24 mock treatment 80.9 -108.0 -0.56 77.6 -109.0 -0.57 -0.7965 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H01 compound treatment 290.0 102.0 0.53 286.9 101.0 0.52 0.7441 1.0 1973517 ChemDiv1_006843 Brc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)oc1N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H02 compound treatment 281.6 93.2 0.49 281.6 95.2 0.49 0.6936 1.0 1549636 ChemDiv1_006844 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H03 compound treatment 292.5 104.0 0.54 291.1 105.0 0.54 0.7687 1.0 1973518 ChemDiv1_006845 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H04 compound treatment 283.4 95.0 0.5 277.8 91.4 0.48 0.6863 0.9998 1149125 ChemDiv1_006846 COc1cccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H05 compound treatment 308.4 120.0 0.63 302.3 116.0 0.6 0.8685 0.9998 1973519 ChemDiv1_006847 CCOc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H06 compound treatment 280.2 91.8 0.48 282.8 96.4 0.5 0.6929 0.9997 1973520 ChemDiv1_006848 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H07 compound treatment 322.6 134.0 0.7 322.8 136.0 0.71 0.9963 1.0 1973521 ChemDiv1_006849 Brc1cccc(c1)N2C(=O)/C(=C/c3cccn3c4ccccc4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H08 compound treatment 279.5 91.0 0.47 282.6 96.2 0.5 0.6895 0.9997 1852049 ChemDiv1_006850 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H09 compound treatment 296.9 108.0 0.57 293.8 107.0 0.56 0.7949 1.0 1973522 ChemDiv1_006851 Brc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)oc1N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H10 compound treatment 283.6 95.2 0.5 280.3 93.9 0.49 0.6962 1.0 1852089 ChemDiv1_006852 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)Nc4ccc(C)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H11 compound treatment 279.2 90.8 0.47 279.8 93.4 0.49 0.6781 0.9999 1219784 ChemDiv1_006853 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(Br)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H12 compound treatment 279.5 91.0 0.47 279.9 93.5 0.49 0.6796 0.9999 1428479 ChemDiv1_006854 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H13 compound treatment 283.4 95.0 0.5 282.5 96.1 0.5 0.7036 1.0 1126349 ChemDiv1_006855 Cn1ccnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4F)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H14 compound treatment 277.8 89.3 0.47 278.8 92.4 0.48 0.6693 0.9999 1472091 ChemDiv1_006856 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cc(C)ccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H15 compound treatment 282.6 94.2 0.49 275.6 89.2 0.46 0.6752 0.9996 1169056 ChemDiv1_006857 COc1ccc(cc1OC)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H16 compound treatment 280.3 91.8 0.48 277.5 91.1 0.47 0.6737 1.0 1681353 ChemDiv1_006858 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H17 compound treatment 276.3 87.8 0.46 280.1 93.7 0.49 0.6685 0.9995 1973523 ChemDiv1_006859 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5cc(OC)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H18 compound treatment 278.8 90.3 0.47 280.7 94.3 0.49 0.68 0.9998 1852148 ChemDiv1_006860 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5nc6ccccc6s5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H19 compound treatment 277.3 88.8 0.46 278.6 92.2 0.48 0.6667 0.9999 1973524 ChemDiv1_006861 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H20 compound treatment 279.3 90.8 0.47 281.7 95.3 0.5 0.6855 0.9998 1683872 ChemDiv1_006862 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5cccc(C)n5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H21 compound treatment 283.0 94.5 0.49 279.5 93.1 0.48 0.6911 1.0 1973525 ChemDiv1_006863 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(cc(c3C#N)C(F)(F)F)c4ccccc4)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H22 compound treatment 276.0 87.5 0.46 271.1 84.7 0.44 0.6344 0.9998 1973526 ChemDiv1_006864 COc1cccc(C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H23 mock treatment 282.3 93.8 0.49 276.2 89.8 0.47 0.6763 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 H24 mock treatment 82.9 -106.0 -0.55 77.0 -109.0 -0.57 -0.7914 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I01 compound treatment 284.0 95.5 0.5 285.7 99.3 0.52 0.7175 0.9998 1405997 ChemDiv1_006865 CCN(CC)S(=O)(=O)c1cccc2nonc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I02 compound treatment 374.0 186.0 0.97 369.2 183.0 0.95 1.3564 1.0 1973527 ChemDiv1_006866 Clc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I03 compound treatment 278.0 89.5 0.47 278.4 92.0 0.48 0.6686 0.9999 1973528 ChemDiv1_006867 CCN(CC)c1cc(N(CC)c2ccccc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I04 compound treatment 306.5 118.0 0.62 302.0 116.0 0.6 0.8604 0.9999 1973529 ChemDiv1_006868 CN1C(=O)C(=Cc2ccc(o2)c3ccc(C)cc3Br)C(=O)N(C)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I05 compound treatment 278.4 90.0 0.47 285.3 98.9 0.51 0.6954 0.999 1973530 ChemDiv1_006869 CN(c1ccccc1)c2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I06 compound treatment 280.6 92.2 0.48 283.1 96.7 0.5 0.6954 0.9997 1973531 ChemDiv1_006870 Clc1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I07 compound treatment 279.8 91.3 0.48 278.4 92.0 0.48 0.6752 1.0 1973532 ChemDiv1_006871 COc1ccc(Nc2cc(N(C)C)c3nonc3c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I08 compound treatment 283.9 95.5 0.5 279.2 92.8 0.48 0.6933 0.9999 1973533 ChemDiv1_006872 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OS(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I09 compound treatment 279.4 91.0 0.47 282.3 95.9 0.5 0.6881 0.9997 1973534 ChemDiv1_006873 CCNc1cc(Nc2ccc(Br)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I10 compound treatment 280.1 91.7 0.48 279.0 92.6 0.48 0.6785 1.0 1973535 ChemDiv1_006874 Clc1ccc(cc1)C(=O)Oc2cccc(/C=C/3\SC(=N)NC3=O)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I11 compound treatment 277.7 89.3 0.47 277.1 90.7 0.47 0.6627 1.0 1973536 ChemDiv1_006875 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)cc(N3CCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I12 compound treatment 280.1 91.7 0.48 279.9 93.5 0.49 0.6818 1.0 1623773 ChemDiv1_006876 CCOC(=O)CSc1nc(N2CCCCC2)c3CCCCc3c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I13 compound treatment 282.5 94.0 0.49 279.7 93.3 0.49 0.6899 1.0 1973537 ChemDiv1_006877 [O-][N+](=O)c1c(Nc2ccc(SC#N)cc2)cc(N3CCOCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I14 compound treatment 278.3 89.8 0.47 280.7 94.3 0.49 0.6781 0.9997 1973538 ChemDiv1_006878 ClC1=CCC2C(C1)C(=O)N(CCN3CCN(CCN4C(=O)C5CC=C(Cl)CC5C4=O)CC3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I15 compound treatment 280.6 92.2 0.48 286.1 99.7 0.52 0.7065 0.9993 1973539 ChemDiv1_006879 Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I16 compound treatment 407.7 219.0 1.14 402.5 216.0 1.12 1.6031 1.0 1973540 ChemDiv1_006880 Brc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I17 compound treatment 280.8 92.3 0.48 279.8 93.4 0.49 0.684 1.0 1973541 ChemDiv1_006881 CCOC(=O)C1=CN(C=C(C1c2ccc(OC)c(Br)c2)C(=O)OCC)c3ccc(OCC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I18 compound treatment 281.2 92.8 0.48 279.8 93.4 0.49 0.6855 1.0 1973542 ChemDiv1_006882 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)c(cc1OC)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I19 compound treatment 278.2 89.8 0.47 281.7 95.3 0.5 0.6814 0.9996 1973543 ChemDiv1_006883 COc1cccc(/C=C\2/SC(=O)N(CCC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I20 compound treatment 279.0 90.5 0.47 280.6 94.2 0.49 0.6803 0.9998 1927381 ChemDiv1_006884 CCOC(=O)c1ccc(cc1)c2ccc(/C=C\3/C(=NN(C3=O)c4ccc(cc4)S(=O)(=O)N)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I21 compound treatment 287.3 98.8 0.52 285.9 99.5 0.52 0.7304 1.0 1928148 ChemDiv1_006885 COc1cc(/C=C\2/SC(=S)N(CCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I22 compound treatment 278.2 89.8 0.47 277.4 91.0 0.47 0.6656 1.0 1973544 ChemDiv1_006886 CCC(Sc1nncn1C)C(=O)Nc2ccc(cc2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I23 mock treatment 282.9 94.5 0.49 276.3 89.9 0.47 0.6789 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 I24 mock treatment 81.5 -107.0 -0.56 74.2 -112.0 -0.58 -0.8068 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J01 compound treatment 283.6 95.2 0.5 283.0 96.6 0.5 0.7061 1.0 1973545 ChemDiv1_006887 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cc(C)cc(C)c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J02 compound treatment 280.2 91.8 0.48 283.8 97.4 0.51 0.6965 0.9996 1341254 ChemDiv1_006888 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J03 compound treatment 280.2 91.8 0.48 281.1 94.7 0.49 0.6866 0.9999 1973546 ChemDiv1_006889 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OC(C)C(=O)O)cc3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J04 compound treatment 286.1 97.7 0.51 281.4 95.0 0.49 0.7095 0.9999 1404566 ChemDiv1_006890 COc1cccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccc(Br)cc5s4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J05 compound treatment 288.5 100.0 0.52 287.6 101.0 0.53 0.7411 1.0 1973547 ChemDiv1_006891 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J06 compound treatment 278.5 90.0 0.47 279.3 92.9 0.48 0.6737 0.9999 1973548 ChemDiv1_006892 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4ccc(C)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J07 compound treatment 276.9 88.5 0.46 279.0 92.6 0.48 0.6667 0.9998 1973549 ChemDiv1_006893 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cc(C)cc(C)c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J08 compound treatment 277.1 88.7 0.46 283.0 96.6 0.5 0.6822 0.9991 1852050 ChemDiv1_006894 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J09 compound treatment 331.6 143.0 0.75 321.9 136.0 0.7 1.0262 0.9996 1973550 ChemDiv1_006895 Cc1ccccc1N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J10 compound treatment 279.9 91.5 0.48 279.4 93.0 0.48 0.6792 1.0 1428037 ChemDiv1_006896 CCN(CC)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J11 compound treatment 276.5 88.0 0.46 283.7 97.3 0.51 0.6825 0.9988 1973551 ChemDiv1_006897 COC(=O)C1=CN(Cc2ccc(OC)cc2)C=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J12 compound treatment 280.5 92.0 0.48 279.4 93.0 0.48 0.6815 1.0 1295220 ChemDiv1_006898 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(F)cc3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J13 compound treatment 277.0 88.5 0.46 278.6 92.2 0.48 0.6656 0.9998 1469846 ChemDiv1_006899 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4Cl)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J14 compound treatment 281.0 92.5 0.48 276.5 90.1 0.47 0.6726 0.9999 1719080 ChemDiv1_006900 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J15 compound treatment 279.2 90.8 0.47 280.3 93.9 0.49 0.68 0.9999 1973552 ChemDiv1_006901 FC(F)(F)c1cc(ccc1Cl)N(CC(=O)N2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J16 compound treatment 281.0 92.5 0.48 278.5 92.1 0.48 0.68 1.0 1553756 ChemDiv1_006902 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J17 compound treatment 281.8 93.3 0.49 282.5 96.1 0.5 0.6977 0.9999 1973553 ChemDiv1_006903 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5cccc(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J18 compound treatment 280.6 92.2 0.48 280.9 94.5 0.49 0.6873 0.9999 1462189 ChemDiv1_006904 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5nc6ccc(Br)cc6s5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J19 compound treatment 280.6 92.2 0.48 281.8 95.4 0.5 0.6907 0.9999 1973554 ChemDiv1_006905 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J20 compound treatment 282.3 93.8 0.49 279.3 92.9 0.48 0.6877 1.0 1436311 ChemDiv1_006906 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccs3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J21 compound treatment 279.7 91.3 0.48 275.1 88.7 0.46 0.6627 0.9999 1533227 ChemDiv1_006907 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(C)cc(C)c3C#N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J22 compound treatment 277.9 89.5 0.47 277.8 91.4 0.48 0.666 1.0 1973555 ChemDiv1_006908 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J23 mock treatment 279.9 91.5 0.48 277.5 91.1 0.47 0.6723 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 J24 mock treatment 79.2 -109.0 -0.57 75.9 -110.0 -0.57 -0.809 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K01 compound treatment 283.2 94.8 0.49 285.6 99.2 0.52 0.7142 0.9998 1973556 ChemDiv1_006909 CCNS(=O)(=O)c1cccc2nonc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K02 compound treatment 329.1 141.0 0.73 327.4 141.0 0.73 1.0372 1.0 1973557 ChemDiv1_006910 O=C1NC(=O)/C(=C\c2ccc(o2)N3CCCCC3)/C(=O)N1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K03 compound treatment 282.5 94.0 0.49 280.7 94.3 0.49 0.6936 1.0 1973558 ChemDiv1_006911 CCN(CC)c1cc(Nc2ccc(Br)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K04 compound treatment 282.1 93.7 0.49 281.9 95.5 0.5 0.6966 1.0 1973559 ChemDiv1_006912 CN1C(=O)C(=Cc2ccc(o2)c3ccc(cc3Br)[N+](=O)[O-])C(=O)N(C)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K05 compound treatment 281.9 93.5 0.49 284.1 97.7 0.51 0.7039 0.9998 1973560 ChemDiv1_006913 [O-][N+](=O)c1c(Nc2ccc(SC#N)cc2)cc(N3CCCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K06 compound treatment 280.1 91.7 0.48 281.4 95.0 0.49 0.6873 0.9999 1973561 ChemDiv1_006914 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K07 compound treatment 276.4 88.0 0.46 279.7 93.3 0.49 0.6674 0.9996 1973562 ChemDiv1_006915 CN(C)c1cc(Nc2ccc(C)c(Cl)c2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K08 compound treatment 279.6 91.2 0.48 285.4 99.0 0.51 0.7002 0.9992 1973563 ChemDiv1_006916 Clc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OC(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K09 compound treatment 282.4 94.0 0.49 280.5 94.1 0.49 0.6925 1.0 1973564 ChemDiv1_006917 CCNc1cc(Nc2ccccc2OC)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K10 compound treatment 281.3 92.8 0.48 279.4 93.0 0.48 0.6844 1.0 1973565 ChemDiv1_006918 Clc1ccc(cc1)C(=O)Oc2ccc(/C=C/3\SC(=N)NC3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K11 compound treatment 280.6 92.2 0.48 281.3 94.9 0.49 0.6888 0.9999 1973566 ChemDiv1_006919 Cc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K12 compound treatment 279.4 91.0 0.47 277.7 91.3 0.47 0.6712 1.0 1239307 ChemDiv1_006920 CC(C)CCSc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K13 compound treatment 275.3 86.8 0.45 278.7 92.3 0.48 0.6597 0.9996 1973567 ChemDiv1_006921 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)cc(N3CCOCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K14 compound treatment 288.5 100.0 0.52 288.0 102.0 0.53 0.7426 1.0 1973568 ChemDiv1_006922 COC(=O)c1ccc(c(C)c1)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K15 compound treatment 281.8 93.3 0.49 279.3 92.9 0.48 0.6859 1.0 1973569 ChemDiv1_006923 COc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc(Br)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K16 compound treatment 271.4 83.0 0.43 270.1 83.7 0.44 0.6137 1.0 1973570 ChemDiv1_006924 Cc1[nH]c2ccccc2c1/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K17 compound treatment 281.3 92.8 0.48 277.7 91.3 0.47 0.6782 0.9999 1973571 ChemDiv1_006925 CCOC(=O)C1=CN(C=C(C1c2cc(Br)ccc2OC)C(=O)OCC)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K18 compound treatment 382.2 194.0 1.01 366.0 180.0 0.93 1.3749 0.9992 1973572 ChemDiv1_006926 CN(C)c1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K19 compound treatment 275.4 87.0 0.45 279.6 93.2 0.48 0.6634 0.9995 1973573 ChemDiv1_006927 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccccc3C(F)(F)F)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K20 compound treatment 277.6 89.2 0.47 272.5 86.1 0.45 0.6454 0.9998 1973574 ChemDiv1_006928 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)S(=O)(=O)N)c4ccc(C)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K21 compound treatment 291.5 103.0 0.54 290.3 104.0 0.54 0.7621 1.0 1973575 ChemDiv1_006929 CCOC(=O)c1c(NC(=O)CCN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S)sc4CCCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K22 compound treatment 280.0 91.5 0.48 275.1 88.7 0.46 0.6638 0.9998 1973576 ChemDiv1_006930 [O-][N+](=O)c1ccc2nc(NC(=O)CSc3nc(c(C#N)c(=O)[nH]3)c4ccccc4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K23 mock treatment 279.6 91.2 0.48 275.2 88.8 0.46 0.6627 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 K24 mock treatment 76.2 -112.0 -0.59 79.7 -107.0 -0.55 -0.8061 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L01 compound treatment 286.4 98.0 0.51 283.3 96.9 0.5 0.7176 1.0 1973577 ChemDiv1_006931 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Cl)c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L02 compound treatment 281.1 92.7 0.48 283.5 97.1 0.5 0.6987 0.9998 1358742 ChemDiv1_006932 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L03 compound treatment 287.3 98.8 0.52 287.5 101.0 0.53 0.7363 1.0 1973578 ChemDiv1_006933 Brc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)oc1N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L04 compound treatment 282.4 94.0 0.49 283.4 97.0 0.5 0.7032 0.9999 1482046 ChemDiv1_006934 COc1ccccc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L05 compound treatment 283.7 95.3 0.5 283.0 96.6 0.5 0.7065 1.0 1973579 ChemDiv1_006935 CCc1ccc(cc1)N2C(=O)/C(=C/c3cc(CC=C)c(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L06 compound treatment 282.2 93.8 0.49 281.6 95.2 0.49 0.6958 1.0 1852025 ChemDiv1_006936 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(cc3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L07 compound treatment 278.5 90.0 0.47 280.7 94.3 0.49 0.6789 0.9998 1973580 ChemDiv1_006937 CCOc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(OC(C)C(=O)O)cc3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L08 compound treatment 282.0 93.5 0.49 282.3 95.9 0.5 0.6977 0.9999 1852051 ChemDiv1_006938 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccc(C)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L09 compound treatment 283.2 94.8 0.49 281.0 94.6 0.49 0.6973 1.0 1973581 ChemDiv1_006939 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc(CC=C)c1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L10 compound treatment 283.6 95.2 0.5 281.6 95.2 0.49 0.701 1.0 1469193 ChemDiv1_006940 CCN(CC)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L11 compound treatment 279.0 90.5 0.47 279.3 92.9 0.48 0.6756 0.9999 1142911 ChemDiv1_006941 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC(=O)C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L12 compound treatment 277.3 88.8 0.46 274.8 88.4 0.46 0.6528 1.0 1714276 ChemDiv1_006942 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L13 compound treatment 281.0 92.5 0.48 277.9 91.5 0.48 0.6778 1.0 1973582 ChemDiv1_006943 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccc(OC)cc3[N+](=O)[O-])sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L14 compound treatment 278.0 89.5 0.47 280.0 93.6 0.49 0.6744 0.9998 1590399 ChemDiv1_006944 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L15 compound treatment 281.0 92.5 0.48 278.0 91.6 0.48 0.6782 1.0 1973583 ChemDiv1_006945 CCOc1ccc(cc1)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L16 compound treatment 278.1 89.7 0.47 280.2 93.8 0.49 0.6756 0.9998 1720467 ChemDiv1_006946 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L17 compound treatment 279.8 91.3 0.48 278.3 91.9 0.48 0.6748 1.0 1973584 ChemDiv1_006947 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L18 compound treatment 276.2 87.8 0.46 279.0 92.6 0.48 0.6641 0.9997 1672165 ChemDiv1_006948 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccnc3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L19 compound treatment 283.3 94.8 0.49 280.0 93.6 0.49 0.694 1.0 1290421 ChemDiv1_006949 Cc1nn(C(=O)CCN2C(=O)c3ccccc3C2=O)c(C)c1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L20 compound treatment 278.7 90.3 0.47 277.4 91.0 0.47 0.6675 1.0 1154110 ChemDiv1_006950 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccsc3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L21 compound treatment 281.1 92.7 0.48 277.3 90.9 0.47 0.676 0.9999 1587713 ChemDiv1_006951 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCc4cc3C#N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L22 compound treatment 283.2 94.8 0.49 278.8 92.4 0.48 0.6892 0.9999 1973585 ChemDiv1_006952 COC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L23 mock treatment 281.3 92.8 0.48 277.9 91.5 0.48 0.6789 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 L24 mock treatment 78.0 -110.0 -0.58 77.5 -109.0 -0.57 -0.8076 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M01 compound treatment 280.0 91.5 0.48 286.4 100.0 0.52 0.7053 0.9991 1973586 ChemDiv1_006953 CCCCNS(=O)(=O)c1cccc2nonc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M02 compound treatment 299.5 111.0 0.58 297.7 111.0 0.58 0.8188 1.0 1973587 ChemDiv1_006954 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)N4CCCCC4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M03 compound treatment 285.5 97.0 0.51 281.1 94.7 0.49 0.7062 0.9999 1973588 ChemDiv1_006955 CCN(CC)c1cc(Nc2ccc(C)c(Cl)c2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M04 compound treatment 294.3 106.0 0.55 288.6 102.0 0.53 0.7662 0.9998 1973589 ChemDiv1_006956 CCOC(=O)c1ccc(cc1)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M05 compound treatment 279.5 91.0 0.47 279.7 93.3 0.49 0.6789 0.9999 1973590 ChemDiv1_006957 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)cc(N3CCCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M06 compound treatment 281.5 93.0 0.49 282.0 95.6 0.5 0.6947 0.9999 1973591 ChemDiv1_006958 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M07 compound treatment 283.8 95.3 0.5 278.9 92.5 0.48 0.6918 0.9999 1973592 ChemDiv1_006959 CN(C)c1cc(Nc2ccc(SC#N)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M08 compound treatment 281.3 92.8 0.48 282.6 96.2 0.5 0.6962 0.9999 1973593 ChemDiv1_006960 COc1ccc(cc1)C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M09 compound treatment 275.5 87.0 0.45 280.3 93.9 0.49 0.6663 0.9993 1973594 ChemDiv1_006961 CCNc1cc(Nc2ccc(Cl)cc2)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M10 compound treatment 288.2 99.8 0.52 287.9 102.0 0.53 0.7411 1.0 1973595 ChemDiv1_006962 COc1cc(/C=C/2\SC(=N)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M11 compound treatment 277.5 89.0 0.46 281.4 95.0 0.49 0.6777 0.9995 1973596 ChemDiv1_006963 COc1ccccc1Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M12 compound treatment 276.4 88.0 0.46 279.3 92.9 0.48 0.666 0.9997 1973597 ChemDiv1_006964 CCOC(=O)C(C)Sc1nc(N2CCOCC2)c3CCCCc3c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M13 compound treatment 279.2 90.8 0.47 281.2 94.8 0.49 0.6833 0.9998 1973598 ChemDiv1_006965 CCN(c1ccccc1)c2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M14 compound treatment 283.7 95.3 0.5 285.0 98.6 0.51 0.7138 0.9999 1973599 ChemDiv1_006966 COC(=O)c1cccc(c1C)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M15 compound treatment 280.0 91.5 0.48 279.6 93.2 0.48 0.6804 1.0 1973600 ChemDiv1_006967 CCOc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3F)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M16 compound treatment 281.4 93.0 0.48 277.1 90.7 0.47 0.6763 0.9999 1973601 ChemDiv1_006968 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M17 compound treatment 279.3 90.8 0.47 279.0 92.6 0.48 0.6756 1.0 1700475 ChemDiv1_006969 COc1ccccc1NC(=O)C2=C(C)NC3=C(C2c4cc(OC)c(OC)c(OC)c4)C(=O)CCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M18 compound treatment 279.6 91.2 0.48 277.5 91.1 0.47 0.6712 1.0 1973602 ChemDiv1_006970 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M19 compound treatment 282.0 93.5 0.49 276.1 89.7 0.47 0.6749 0.9997 1973603 ChemDiv1_006971 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(cc3)C(=O)C)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M20 compound treatment 282.8 94.3 0.49 277.7 91.3 0.47 0.6837 0.9998 1973604 ChemDiv1_006972 COC(=O)c1cccc(c1)c2ccc(/C=C\3/C(=NN(C3=O)c4ccc(C)c(Cl)c4)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M21 compound treatment 311.5 123.0 0.64 312.8 126.0 0.66 0.9186 0.9999 1973605 ChemDiv1_006973 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3sc4CCCCc4c3C(=O)N)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M22 compound treatment 275.5 87.0 0.45 276.3 89.9 0.47 0.6516 0.9999 1973606 ChemDiv1_006974 CCCc1nnc(NC(=O)CSc2nc(c(C#N)c(=O)[nH]2)c3cccc(OC)c3)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M23 mock treatment 280.6 92.2 0.48 278.8 92.4 0.48 0.6796 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 M24 mock treatment 194.2 5.75 0.03 186.5 0.125 0.0 0.0217 0.7223 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N01 compound treatment 280.6 92.2 0.48 284.4 98.0 0.51 0.7002 0.9996 1973607 ChemDiv1_006975 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N02 compound treatment 280.4 92.0 0.48 283.1 96.7 0.5 0.6947 0.9997 1405780 ChemDiv1_006976 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N03 compound treatment 308.6 120.0 0.63 311.8 125.0 0.65 0.9042 0.9998 1973608 ChemDiv1_006977 CCOc1cccc(c1)N2C(=O)/C(=C/c3cc(CC=C)c(O)c(OCC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N04 compound treatment 281.8 93.3 0.49 283.9 97.5 0.51 0.7028 0.9998 1726565 ChemDiv1_006978 COc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N05 compound treatment 282.0 93.5 0.49 276.1 89.7 0.47 0.6749 0.9997 1973609 ChemDiv1_006979 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N06 compound treatment 280.3 91.8 0.48 281.4 95.0 0.49 0.6881 0.9999 1852032 ChemDiv1_006980 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(cc3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N07 compound treatment 287.2 98.8 0.52 282.1 95.7 0.5 0.7161 0.9998 1973610 ChemDiv1_006981 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(CC=C)c(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N08 compound treatment 283.1 94.7 0.49 277.7 91.3 0.47 0.6848 0.9998 1852052 ChemDiv1_006982 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4cc(C)ccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N09 compound treatment 280.2 91.8 0.48 280.5 94.1 0.49 0.6844 0.9999 1973611 ChemDiv1_006983 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N10 compound treatment 278.8 90.3 0.47 277.3 90.9 0.47 0.6675 1.0 1584625 ChemDiv1_006984 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N11 compound treatment 277.7 89.3 0.47 277.9 91.5 0.48 0.6656 0.9999 1649216 ChemDiv1_006985 COc1cc(C2Nc3cc(C)c(C)cc3NC4=C2C(=O)CC(C)(C)C4)c(OC)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N12 compound treatment 278.3 89.8 0.47 279.6 93.2 0.48 0.6741 0.9999 1128379 ChemDiv1_006986 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C(=O)Nc5ccc(Br)cn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N13 compound treatment 280.2 91.8 0.48 284.1 97.7 0.51 0.6976 0.9996 1973612 ChemDiv1_006987 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccc(cc3)C(=O)C)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N14 compound treatment 278.9 90.5 0.47 279.0 92.6 0.48 0.6741 0.9999 1546442 ChemDiv1_006988 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N15 compound treatment 277.8 89.3 0.47 280.7 94.3 0.49 0.6763 0.9997 1720250 ChemDiv1_006989 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)c3ccccc3Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N16 compound treatment 279.5 91.0 0.47 282.5 96.1 0.5 0.6892 0.9997 1426386 ChemDiv1_006990 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N17 compound treatment 281.0 92.5 0.48 283.9 97.5 0.51 0.6998 0.9997 1973613 ChemDiv1_006991 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N18 compound treatment 276.9 88.5 0.46 277.7 91.3 0.47 0.6619 0.9999 1309408 ChemDiv1_006992 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5ccc(Br)cn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N19 compound treatment 277.5 89.0 0.46 281.6 95.2 0.49 0.6785 0.9995 1623172 ChemDiv1_006993 Cc1ccc(COc2ccc(Br)cc2C=c3sc4nc5ccccc5n4c3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N20 compound treatment 279.6 91.2 0.48 279.5 93.1 0.48 0.6785 1.0 1652312 ChemDiv1_006994 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccsc3)C(=O)Nc4cc(C)ccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N21 compound treatment 276.9 88.5 0.46 281.2 94.8 0.49 0.6748 0.9995 1538252 ChemDiv1_006995 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCCc4cc3C#N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N22 compound treatment 277.6 89.2 0.47 282.7 96.3 0.5 0.6829 0.9993 1973614 ChemDiv1_006996 COc1ccc(OC)c(c1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N23 mock treatment 278.2 89.8 0.47 278.6 92.2 0.48 0.67 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 N24 mock treatment 191.5 3.05 0.02 199.1 12.7 0.07 0.058 0.8529 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O01 compound treatment 286.0 97.5 0.51 289.6 103.0 0.54 0.7392 0.9996 1973615 ChemDiv1_006997 CCCCN(CCCC)S(=O)(=O)c1cccc2nonc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O02 compound treatment 324.3 136.0 0.71 319.6 133.0 0.69 0.9908 0.9999 1973616 ChemDiv1_006998 Brc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O03 compound treatment 284.4 96.0 0.5 282.1 95.7 0.5 0.7058 1.0 1973617 ChemDiv1_006999 CCN(CC)c1cc(Nc2ccccc2OC)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O04 compound treatment 284.8 96.3 0.5 283.3 96.9 0.5 0.7117 1.0 1973618 ChemDiv1_007000 CN1C(=O)C(=Cc2cc(C)n(c2C)c3ccc(C)c(c3)[N+](=O)[O-])C(=O)N(C)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O05 compound treatment 279.7 91.3 0.48 278.1 91.7 0.48 0.6737 1.0 1973619 ChemDiv1_007001 Cc1ccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O06 compound treatment 284.3 95.8 0.5 282.8 96.4 0.5 0.708 1.0 1973620 ChemDiv1_007002 Clc1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O07 compound treatment 283.1 94.7 0.49 281.4 95.0 0.49 0.6984 1.0 1973621 ChemDiv1_007003 CCN(c1ccccc1)c2cc(N(C)C)c3nonc3c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O08 compound treatment 276.6 88.2 0.46 278.2 91.8 0.48 0.6627 0.9998 1973622 ChemDiv1_007004 COc1ccc(cc1)C(=O)Oc2c(Cl)cc(C=C3C(=O)NC(=O)NC3=O)cc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O09 compound treatment 282.5 94.0 0.49 279.4 93.0 0.48 0.6888 1.0 1973623 ChemDiv1_007005 CCOc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O10 compound treatment 283.3 94.8 0.49 285.1 98.7 0.51 0.7127 0.9998 1973624 ChemDiv1_007006 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O11 compound treatment 279.8 91.3 0.48 276.8 90.4 0.47 0.6693 1.0 1973625 ChemDiv1_007007 [O-][N+](=O)c1c(Nc2ccc(Cl)cc2)cc(N3CCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O12 compound treatment 278.0 89.5 0.47 277.8 91.4 0.48 0.6664 1.0 1973626 ChemDiv1_007008 CCCCCSc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O13 compound treatment 280.3 91.8 0.48 279.1 92.7 0.48 0.6796 1.0 1973627 ChemDiv1_007009 COc1ccccc1Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O14 compound treatment 284.0 95.5 0.5 286.3 99.9 0.52 0.7197 0.9998 1973628 ChemDiv1_007010 CCOC(=O)c1cccc(c1)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O15 compound treatment 283.3 94.8 0.49 277.6 91.2 0.47 0.6852 0.9998 1378791 ChemDiv1_007011 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccccc3OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O16 compound treatment 281.6 93.2 0.49 278.4 92.0 0.48 0.6818 1.0 1973629 ChemDiv1_007012 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O17 compound treatment 280.6 92.2 0.48 279.6 93.2 0.48 0.6826 1.0 1973630 ChemDiv1_007013 CCOC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OCC)c3ccc(OCC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O18 compound treatment 277.8 89.3 0.47 279.5 93.1 0.48 0.6719 0.9998 1973631 ChemDiv1_007014 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O19 compound treatment 280.3 91.8 0.48 280.2 93.8 0.49 0.6837 1.0 1973632 ChemDiv1_007015 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(cc3)C(=O)O)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O20 compound treatment 280.8 92.3 0.48 278.5 92.1 0.48 0.6793 1.0 1192194 ChemDiv1_007016 COc1ccc2nc(SCC(=O)O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O21 compound treatment 283.7 95.3 0.5 281.5 95.1 0.49 0.701 1.0 1973633 ChemDiv1_007017 Cc1c(NC(=O)CCN2C(=O)/C(=C/c3cccs3)/SC2=S)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O22 compound treatment 281.4 93.0 0.48 277.5 91.1 0.47 0.6778 0.9999 1973634 ChemDiv1_007018 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3F)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O23 mock treatment 281.4 93.0 0.48 275.6 89.2 0.46 0.6708 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 O24 mock treatment 98.7 -89.8 -0.47 96.0 -90.4 -0.47 -0.6632 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P01 compound treatment 284.6 96.2 0.5 278.0 91.6 0.48 0.6914 0.9997 1973635 ChemDiv1_007019 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)c(C)c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P02 compound treatment 279.0 90.5 0.47 282.6 96.2 0.5 0.6877 0.9996 1160446 ChemDiv1_007020 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P03 compound treatment 284.7 96.3 0.5 282.0 95.6 0.5 0.7065 1.0 1973636 ChemDiv1_007021 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P04 compound treatment 284.1 95.7 0.5 281.8 95.4 0.5 0.7036 1.0 1388647 ChemDiv1_007022 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Br)c3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P05 compound treatment 285.6 97.2 0.51 280.8 94.4 0.49 0.7054 0.9999 1973637 ChemDiv1_007023 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc(CC=C)c1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P06 compound treatment 280.1 91.7 0.48 281.7 95.3 0.5 0.6884 0.9998 1556239 ChemDiv1_007024 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3Cl)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P07 compound treatment 281.5 93.0 0.49 280.8 94.4 0.49 0.6903 1.0 1973638 ChemDiv1_007025 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Br)c3)cc1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P08 compound treatment 280.3 91.8 0.48 282.6 96.2 0.5 0.6925 0.9998 1696155 ChemDiv1_007026 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P09 compound treatment 296.4 108.0 0.56 292.9 107.0 0.55 0.7897 1.0 1973639 ChemDiv1_007027 Cc1cc(C)cc(c1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P10 compound treatment 284.1 95.7 0.5 278.2 91.8 0.48 0.6903 0.9998 1125797 ChemDiv1_007028 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P11 compound treatment 278.3 89.8 0.47 281.8 95.4 0.5 0.6822 0.9996 1304688 ChemDiv1_007029 COc1cc(C2Nc3cc(C)c(C)cc3NC4=C2C(=O)CC(C)(C)C4)c(Br)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P12 compound treatment 280.6 92.2 0.48 281.9 95.5 0.5 0.691 0.9999 1340949 ChemDiv1_007030 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C(=O)Nc5ccc(C)cn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P13 compound treatment 277.7 89.3 0.47 279.4 93.0 0.48 0.6711 0.9998 1668988 ChemDiv1_007031 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccccc3C(=O)OC)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P14 compound treatment 281.2 92.8 0.48 279.9 93.5 0.49 0.6859 1.0 1654466 ChemDiv1_007032 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Br)cc3)C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P15 compound treatment 279.0 90.5 0.47 280.8 94.4 0.49 0.6811 0.9998 1973640 ChemDiv1_007033 Cc1c(NC(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P16 compound treatment 278.0 89.5 0.47 279.6 93.2 0.48 0.673 0.9998 1713669 ChemDiv1_007034 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Cl)c3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P17 compound treatment 290.8 102.0 0.53 285.2 98.8 0.51 0.7408 0.9998 1973641 ChemDiv1_007035 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(cc5)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P18 compound treatment 281.4 93.0 0.48 276.9 90.5 0.47 0.6756 0.9999 1614227 ChemDiv1_007036 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5cccc(C)n5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P19 compound treatment 281.0 92.5 0.48 279.0 92.6 0.48 0.6818 1.0 1973642 ChemDiv1_007037 Cc1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P20 compound treatment 277.6 89.2 0.47 278.8 92.4 0.48 0.6686 0.9999 1973643 ChemDiv1_007038 Cc1ccc(cc1)C(=O)C2=C(N)OC3=C(C2c4ccccc4Cl)C(=O)CCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P21 compound treatment 278.6 90.2 0.47 282.2 95.8 0.5 0.6847 0.9996 1349846 ChemDiv1_007039 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCCCc4cc3C#N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P22 compound treatment 283.7 95.3 0.5 277.7 91.3 0.47 0.687 0.9997 1973644 ChemDiv1_007040 CCOC(=O)C1=C(N)OC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P23 mock treatment 283.1 94.7 0.49 280.4 94.0 0.49 0.6947 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.606 P24 mock treatment 96.8 -91.7 -0.48 97.9 -88.5 -0.46 -0.6633 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A01 compound treatment 285.2 97.8 0.51 286.5 99.1 0.52 0.7248 1.0 1973645 ChemDiv1_007041 COC(=O)C1=C(N)OC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A02 compound treatment 285.4 98.0 0.51 285.5 98.1 0.51 0.7219 1.0 1536804 ChemDiv1_007042 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A03 compound treatment 283.3 95.9 0.5 285.7 98.3 0.51 0.7149 0.9999 1973646 ChemDiv1_007043 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A04 compound treatment 276.5 89.1 0.46 278.4 91.0 0.47 0.663 1.0 1742982 ChemDiv1_007044 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A05 compound treatment 279.2 91.8 0.48 281.7 94.3 0.49 0.685 0.9999 1973647 ChemDiv1_007045 COC(=O)C1=C(N)OC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A06 compound treatment 284.7 97.3 0.51 285.8 98.4 0.51 0.7204 1.0 1288807 ChemDiv1_007046 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A07 compound treatment 278.7 91.3 0.48 282.0 94.6 0.49 0.6843 0.9999 1973648 ChemDiv1_007047 COC(=O)C1=C(N)OC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A08 compound treatment 279.6 92.2 0.48 275.5 88.1 0.46 0.6637 0.9997 1973649 ChemDiv1_007048 Cc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A09 compound treatment 274.4 87.0 0.45 282.2 94.8 0.49 0.6692 0.9991 1973650 ChemDiv1_007049 COC(=O)C1=C(N)OC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A10 compound treatment 278.3 90.9 0.47 281.5 94.1 0.49 0.681 0.9999 1653667 ChemDiv1_007050 CC(=O)N1N=C(CC1c2cn(nc2c3ccc(C)cc3)c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A11 compound treatment 280.2 92.8 0.48 282.4 95.0 0.49 0.6913 0.9999 1973651 ChemDiv1_007051 CCOC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A12 compound treatment 275.1 87.7 0.46 279.1 91.7 0.48 0.6604 0.9998 1698924 ChemDiv1_007052 CCc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc5OCCOc5c4)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A13 compound treatment 287.0 99.6 0.52 282.7 95.3 0.5 0.7175 0.9997 1973652 ChemDiv1_007053 COc1cc(C=c2sc3nc4c(C)cccc4n3c2=O)cc(Br)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A14 compound treatment 276.3 88.9 0.46 282.2 94.8 0.49 0.6762 0.9995 1973653 ChemDiv1_007054 Cc1ccc2n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A15 compound treatment 272.8 85.4 0.45 278.9 91.5 0.48 0.6511 0.9995 1973654 ChemDiv1_007055 COc1ccc(cc1OC)N(CC(=O)Nc2ccccc2Br)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A16 compound treatment 278.2 90.8 0.47 274.7 87.3 0.45 0.6556 0.9998 1973655 ChemDiv1_007056 Cc1ccc2n(CC(=O)Nc3ccc(cc3)C(F)(F)F)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A17 compound treatment 275.5 88.1 0.46 273.5 86.1 0.45 0.6413 0.9999 1225499 ChemDiv1_007057 COC(=O)c1ccccc1NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A18 compound treatment 273.6 86.2 0.45 277.0 89.6 0.47 0.6471 0.9998 1973656 ChemDiv1_007058 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccc(F)cc4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A19 compound treatment 270.9 83.5 0.44 277.0 89.6 0.47 0.6372 0.9994 1973657 ChemDiv1_007059 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(C)c(c3)[N+](=O)[O-])/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A20 compound treatment 277.2 89.8 0.47 276.7 89.3 0.46 0.6593 1.0 1973658 ChemDiv1_007060 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccc(Cl)c(C)c4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A21 compound treatment 283.7 96.3 0.5 286.5 99.1 0.52 0.7193 0.9999 1973659 ChemDiv1_007061 [O-][N+](=O)c1cc(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)c(cc1N4CCOCC4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A22 compound treatment 276.2 88.8 0.46 277.3 89.9 0.47 0.6578 1.0 1327438 ChemDiv1_007062 Fc1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4Cl)c(F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A23 mock treatment 284.8 97.4 0.51 278.4 91.0 0.47 0.6936 0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 A24 mock treatment 78.3 -109.0 -0.57 81.8 -106.0 -0.55 -0.7908 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B01 compound treatment 286.4 99.0 0.52 284.8 97.4 0.51 0.723 1.0 1973660 ChemDiv1_007063 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(ccc24)[N+](=O)[O-])c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B02 compound treatment 281.3 93.9 0.49 279.4 92.0 0.48 0.6843 0.9999 1496615 ChemDiv1_007064 Clc1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B03 compound treatment 281.3 93.9 0.49 286.7 99.3 0.52 0.7112 0.9997 1699976 ChemDiv1_007065 COc1ccc(NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B04 compound treatment 278.5 91.1 0.48 282.4 95.0 0.49 0.685 0.9998 1583855 ChemDiv1_007066 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B05 compound treatment 276.7 89.3 0.47 279.2 91.8 0.48 0.6666 0.9999 1335280 ChemDiv1_007067 Cc1ccc(cc1)c2csc(NC(=O)N3CCOCC3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B06 compound treatment 278.3 90.9 0.47 282.4 95.0 0.49 0.6843 0.9998 1185860 ChemDiv1_007068 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)S(=O)(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B07 compound treatment 274.0 86.6 0.45 278.7 91.3 0.47 0.6548 0.9997 1927002 ChemDiv1_007069 O=C1Nc2ccccc2C13C4=C(NC5=C3C(=O)c6ccccc56)c7ccccc7C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B08 compound treatment 276.1 88.7 0.46 277.9 90.5 0.47 0.6596 1.0 1519708 ChemDiv1_007070 CC(C)CC(NC(=O)c1ccc2OCCOc2c1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B09 compound treatment 276.8 89.4 0.47 278.1 90.7 0.47 0.663 1.0 1973661 ChemDiv1_007071 CCCCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B10 compound treatment 278.5 91.1 0.48 280.5 93.1 0.48 0.6781 1.0 1402828 ChemDiv1_007072 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Br)cc3F)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B11 compound treatment 275.7 88.3 0.46 280.8 93.4 0.49 0.6688 0.9996 1973662 ChemDiv1_007073 CC(C)C1=CC23CCC4C(C)(CCCC4(C)C3CC1C5C2C(=O)N(CCO)C5=O)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B12 compound treatment 278.4 91.0 0.47 280.4 93.0 0.48 0.6773 1.0 1973663 ChemDiv1_007074 COc1ccc(Oc2c(oc3cc(OC(C)C(=O)OC(C)C)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B13 compound treatment 276.9 89.5 0.47 280.4 93.0 0.48 0.6718 0.9998 1305650 ChemDiv1_007075 COc1cccc2c(C)nc(Nc3nc(O)c4ccccc4n3)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B14 compound treatment 278.4 91.0 0.47 274.9 87.5 0.45 0.6571 0.9998 1660710 ChemDiv1_007076 CC(C)COC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B15 compound treatment 278.5 91.1 0.48 274.6 87.2 0.45 0.6564 0.9997 1657301 ChemDiv1_007077 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4ccc(OC)cc4OC)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B16 compound treatment 280.2 92.8 0.48 283.4 96.0 0.5 0.695 0.9999 1481833 ChemDiv1_007078 CC(C)OC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B17 compound treatment 280.0 92.6 0.48 279.9 92.5 0.48 0.6814 1.0 1490349 ChemDiv1_007079 Cc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B18 compound treatment 278.6 91.2 0.48 272.4 85.0 0.44 0.6486 0.9993 1973664 ChemDiv1_007080 CCCOC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B19 compound treatment 277.4 90.0 0.47 277.6 90.2 0.47 0.6633 1.0 1669068 ChemDiv1_007081 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)s3)c(=O)n2C1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B20 compound treatment 273.9 86.5 0.45 279.8 92.4 0.48 0.6585 0.9995 1973665 ChemDiv1_007082 CCOC(=O)CSc1ncn[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B21 compound treatment 272.3 84.9 0.44 277.5 90.1 0.47 0.6442 0.9996 1725241 ChemDiv1_007083 CCC(C)OC(=O)C1=C(C)NC(=O)NC1c2ccc(OC)c(OCc3ccccc3)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B22 compound treatment 281.8 94.4 0.49 279.8 92.4 0.48 0.6876 0.9999 1973666 ChemDiv1_007084 Cc1nnc(NC(=O)CCN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B23 mock treatment 280.2 92.8 0.48 277.4 90.0 0.47 0.6729 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 B24 mock treatment 78.9 -109.0 -0.57 79.0 -108.0 -0.56 -0.7988 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C01 compound treatment 283.2 95.8 0.5 285.9 98.5 0.51 0.7152 0.9999 1973667 ChemDiv1_007085 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C02 compound treatment 280.7 93.3 0.49 281.9 94.5 0.49 0.6913 1.0 1214561 ChemDiv1_007086 Cc1ccc(cc1)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C03 compound treatment 281.1 93.7 0.49 281.0 93.6 0.49 0.6895 1.0 1973668 ChemDiv1_007087 COC(=O)C1=C(N)OC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C04 compound treatment 277.5 90.1 0.47 281.0 93.6 0.49 0.6762 0.9998 1194008 ChemDiv1_007088 Cc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C05 compound treatment 287.5 100.0 0.52 283.8 96.4 0.5 0.7234 0.9998 1973669 ChemDiv1_007089 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C06 compound treatment 289.0 102.0 0.53 295.0 108.0 0.56 0.7701 0.9996 1575177 ChemDiv1_007090 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C07 compound treatment 280.4 93.0 0.48 277.0 89.6 0.47 0.6722 0.9998 1973670 ChemDiv1_007091 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C08 compound treatment 273.1 85.7 0.45 281.4 94.0 0.49 0.6614 0.999 1186824 ChemDiv1_007092 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C09 compound treatment 278.4 91.0 0.47 283.9 96.5 0.5 0.6902 0.9996 1973671 ChemDiv1_007093 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(Cl)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C10 compound treatment 281.5 94.1 0.49 274.3 86.9 0.45 0.6663 0.9991 1245121 ChemDiv1_007094 CC(=O)N1N=C(CC1c2cn(nc2c3ccc(C)cc3)c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C11 compound treatment 280.5 93.1 0.49 280.7 93.3 0.48 0.6862 1.0 1973672 ChemDiv1_007095 COC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C12 compound treatment 275.2 87.8 0.46 277.6 90.2 0.47 0.6552 0.9999 1333452 ChemDiv1_007096 Fc1ccc(cc1)c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C13 compound treatment 278.4 91.0 0.47 279.3 91.9 0.48 0.6733 1.0 1973673 ChemDiv1_007097 CC(=O)CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C14 compound treatment 277.5 90.1 0.47 273.7 86.3 0.45 0.6494 0.9997 1973674 ChemDiv1_007098 Cc1ccc2n(CC(=O)Nc3ccc(OC(F)(F)F)cc3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C15 compound treatment 275.0 87.6 0.46 282.7 95.3 0.5 0.6732 0.9992 1697867 ChemDiv1_007099 CCOc1ccc(cc1)N(CC(=O)Nc2cc(OC)ccc2OC)S(=O)(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C16 compound treatment 277.9 90.5 0.47 276.6 89.2 0.46 0.6615 1.0 1973675 ChemDiv1_007100 Cc1ccc2n(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C17 compound treatment 281.2 93.8 0.49 279.1 91.7 0.48 0.6829 0.9999 1195754 ChemDiv1_007101 CCOC(=O)c1ccccc1NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C18 compound treatment 276.3 88.9 0.46 282.2 94.8 0.49 0.6762 0.9995 1973676 ChemDiv1_007102 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccccc4F)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C19 compound treatment 334.1 147.0 0.77 339.1 152.0 0.79 1.0985 0.9999 1973677 ChemDiv1_007103 Cc1ccc(cc1Cl)N2C(=N)S/C(=C\c3ccccc3OCC(=O)O)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C20 compound treatment 278.0 90.6 0.47 275.8 88.4 0.46 0.6589 0.9999 1973678 ChemDiv1_007104 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccc(F)cc4)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C21 compound treatment 281.0 93.6 0.49 283.0 95.6 0.5 0.6965 1.0 1973679 ChemDiv1_007105 CCC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3ccccc3F)\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C22 compound treatment 275.7 88.3 0.46 277.6 90.2 0.47 0.6571 1.0 1266308 ChemDiv1_007106 COc1ccc(cc1OC)c2nc(Nc3ccc4OCCOc4c3)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C23 mock treatment 279.5 92.1 0.48 279.3 91.9 0.48 0.6773 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 C24 mock treatment 77.0 -110.0 -0.58 79.5 -108.0 -0.56 -0.804 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D01 compound treatment 285.9 98.5 0.51 281.5 94.1 0.49 0.709 0.9997 1973680 ChemDiv1_007107 COc1ccc(N(CC(=O)Nc2ccc(Cl)cc2C)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D02 compound treatment 281.6 94.2 0.49 286.3 98.9 0.51 0.7108 0.9997 1263212 ChemDiv1_007108 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D03 compound treatment 278.1 90.7 0.47 278.1 90.7 0.47 0.6678 1.0 1285012 ChemDiv1_007109 CCOc1ccc(cc1)N(CC(=O)Nc2ccccc2C(=O)OC)S(=O)(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D04 compound treatment 278.0 90.6 0.47 276.8 89.4 0.46 0.6626 1.0 1973681 ChemDiv1_007110 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cccc(c2)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D05 compound treatment 279.3 91.9 0.48 276.8 89.4 0.46 0.6674 0.9999 1500037 ChemDiv1_007111 N#CCn1c2ccccc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D06 compound treatment 283.0 95.6 0.5 276.2 88.8 0.46 0.6788 0.9993 1576504 ChemDiv1_007112 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc(Br)cc3)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D07 compound treatment 278.4 91.0 0.47 280.0 92.6 0.48 0.6758 1.0 1375317 ChemDiv1_007113 COc1cccc(Nc2nc(Cl)nc(Nc3cccc(OC)c3)n2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D08 compound treatment 277.4 90.0 0.47 281.0 93.6 0.49 0.6758 0.9998 1973682 ChemDiv1_007114 CCCCC(NC(=O)c1ccc2OCCOc2c1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D09 compound treatment 277.7 90.3 0.47 278.2 90.8 0.47 0.6666 1.0 1458209 ChemDiv1_007115 CCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D10 compound treatment 274.6 87.2 0.45 281.0 93.6 0.49 0.6655 0.9994 1973683 ChemDiv1_007116 CCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D11 compound treatment 280.6 93.2 0.49 277.1 89.7 0.47 0.6733 0.9998 1784333 ChemDiv1_007117 O=C(Nc1ccc(cc1)N2C(=O)C3CC=CCC3C2=O)c4ccc(cc4)N5C(=O)C6CC=CCC6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D12 compound treatment 275.4 88.0 0.46 277.5 90.1 0.47 0.6556 0.9999 1973684 ChemDiv1_007118 CCCOC(=O)COc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D13 compound treatment 279.7 92.3 0.48 275.9 88.5 0.46 0.6656 0.9997 1253470 ChemDiv1_007119 Cc1cccc2c(C)nc(Nc3nc(=O)cc([nH]3)c4ccccc4)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D14 compound treatment 279.9 92.5 0.48 279.8 92.4 0.48 0.6806 1.0 1422421 ChemDiv1_007120 Brc1ccccc1Oc2coc3cc(OCC(=O)OCc4ccccc4)ccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D15 compound treatment 276.1 88.7 0.46 278.7 91.3 0.47 0.6626 0.9999 1479986 ChemDiv1_007121 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D16 compound treatment 295.3 108.0 0.56 291.7 104.0 0.54 0.7812 0.9998 1973685 ChemDiv1_007122 CC(C)OC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D17 compound treatment 277.2 89.8 0.47 274.3 86.9 0.45 0.6505 0.9998 1973686 ChemDiv1_007123 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccncc2)c3ccc(Cl)c(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D18 compound treatment 277.3 89.9 0.47 278.7 91.3 0.47 0.667 1.0 1973687 ChemDiv1_007124 CCOCCOC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D19 compound treatment 281.6 94.2 0.49 276.5 89.1 0.46 0.6748 0.9996 1312383 ChemDiv1_007125 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4n(C)c(=O)n(C)c4c3)c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D20 compound treatment 275.8 88.4 0.46 280.9 93.5 0.49 0.6696 0.9997 1973688 ChemDiv1_007126 COCCOC(=O)CSc1ncn[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D21 compound treatment 275.4 88.0 0.46 278.3 90.9 0.47 0.6585 0.9999 1973689 ChemDiv1_007127 CCOC(=O)C1=CN(C=C(C1c2ccc(OC)c(Br)c2)C(=O)OCC)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D22 compound treatment 282.1 94.7 0.49 279.3 91.9 0.48 0.6869 0.9999 1973690 ChemDiv1_007128 CCOC(=O)c1ccc(NC(=O)CCN2C(=O)/C(=C\C(=C\c3ccccc3)\C)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D23 mock treatment 277.7 90.3 0.47 281.4 94.0 0.49 0.6784 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 D24 mock treatment 77.6 -110.0 -0.57 76.1 -111.0 -0.58 -0.8143 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E01 compound treatment 286.0 98.6 0.51 281.2 93.8 0.49 0.7083 0.9996 1973691 ChemDiv1_007129 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E02 compound treatment 279.4 92.0 0.48 277.9 90.5 0.47 0.6718 1.0 1923834 ChemDiv1_007130 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E03 compound treatment 279.8 92.4 0.48 280.1 92.7 0.48 0.6814 1.0 1973692 ChemDiv1_007131 COC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3Cl)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E04 compound treatment 282.9 95.5 0.5 278.7 91.3 0.47 0.6877 0.9997 1973693 ChemDiv1_007132 CC(=O)N1N=C(CC1c2ccc(cc2)[N+](=O)[O-])c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E05 compound treatment 283.5 96.1 0.5 279.5 92.1 0.48 0.6928 0.9997 1973694 ChemDiv1_007133 COC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E06 compound treatment 287.6 100.0 0.52 286.7 99.3 0.52 0.7344 1.0 1973695 ChemDiv1_007134 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E07 compound treatment 278.6 91.2 0.48 280.7 93.3 0.48 0.6792 1.0 1973696 ChemDiv1_007135 COC(=O)C1=C(N)OC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E08 compound treatment 285.6 98.2 0.51 285.7 98.3 0.51 0.7234 1.0 1973697 ChemDiv1_007136 COc1ccc(OC)c(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E09 compound treatment 282.0 94.6 0.49 283.3 95.9 0.5 0.7013 1.0 1973698 ChemDiv1_007137 COC(=O)C1=C(N)OC2=C(C1c3cccc(Cl)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E10 compound treatment 280.6 93.2 0.49 279.6 92.2 0.48 0.6825 1.0 1973699 ChemDiv1_007138 Brc1ccc(OCc2ccccc2)c(C=C3C(=O)NC(=O)NC3=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E11 compound treatment 279.7 92.3 0.48 279.0 91.6 0.48 0.677 1.0 1973700 ChemDiv1_007139 CCOC(=O)C1=C(N)OC2=C(C1c3ccsc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E12 compound treatment 285.8 98.4 0.51 277.7 90.3 0.47 0.6947 0.999 1240277 ChemDiv1_007140 Clc1cccc(c1)c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E13 compound treatment 280.7 93.3 0.49 279.8 92.4 0.48 0.6836 1.0 1600172 ChemDiv1_007141 O=C(CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1)NCC6CCCO6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E14 compound treatment 277.9 90.5 0.47 276.3 88.9 0.46 0.6604 0.9999 1973701 ChemDiv1_007142 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E15 compound treatment 274.7 87.3 0.46 280.9 93.5 0.49 0.6655 0.9995 1484052 ChemDiv1_007143 CCOc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E16 compound treatment 281.0 93.6 0.49 282.3 94.9 0.49 0.6939 1.0 1973702 ChemDiv1_007144 Clc1ccc2n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E17 compound treatment 279.9 92.5 0.48 276.6 89.2 0.46 0.6689 0.9998 1973703 ChemDiv1_007145 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E18 compound treatment 280.0 92.6 0.48 278.7 91.3 0.47 0.677 1.0 1973704 ChemDiv1_007146 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E19 compound treatment 263.6 76.2 0.4 259.6 72.2 0.38 0.5463 0.9996 1973705 ChemDiv1_007147 Brc1ccc(OCC=C)c(/C=C/2\Sc3ccccc3C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E20 compound treatment 279.5 92.1 0.48 280.8 93.4 0.49 0.6828 1.0 1123926 ChemDiv1_007148 CCOC(=O)c1nc(Nc2cccc(Cl)c2C)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E21 compound treatment 277.6 90.2 0.47 275.8 88.4 0.46 0.6575 0.9999 1973706 ChemDiv1_007149 Cn1c(nc2ccccc12)c3nonc3NC(=O)CSc4nc5ccccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E22 compound treatment 273.9 86.5 0.45 275.9 88.5 0.46 0.6442 1.0 1973707 ChemDiv1_007150 CCOC(=O)c1nc(Nc2ccc(cc2)C(F)(F)F)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E23 mock treatment 280.3 92.9 0.48 284.7 97.3 0.51 0.7001 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 E24 mock treatment 80.6 -107.0 -0.56 75.4 -112.0 -0.58 -0.8058 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F01 compound treatment 281.2 93.8 0.49 287.2 99.8 0.52 0.7126 0.9996 1973708 ChemDiv1_007151 COc1ccc(CCNC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F02 compound treatment 314.7 127.0 0.66 316.1 129.0 0.67 0.9424 1.0 1973709 ChemDiv1_007152 O=C(NCCSCc1ccccc1)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F03 compound treatment 282.4 95.0 0.5 283.5 96.1 0.5 0.7035 1.0 1393797 ChemDiv1_007153 Clc1ccc(cc1)C(=O)Nc2nc3cc(NC(=O)c4ccc(Cl)cc4)ccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F04 compound treatment 278.3 90.9 0.47 282.7 95.3 0.5 0.6854 0.9998 1613452 ChemDiv1_007154 Clc1ccc(cc1Cl)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F05 compound treatment 278.9 91.5 0.48 279.5 92.1 0.48 0.6758 1.0 1724714 ChemDiv1_007155 OCCNC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F06 compound treatment 280.5 93.1 0.49 280.1 92.7 0.48 0.684 1.0 1973710 ChemDiv1_007156 Clc1cccc(N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccccc3)c1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F07 compound treatment 279.7 92.3 0.48 278.0 90.6 0.47 0.6733 0.9999 1925757 ChemDiv1_007157 COc1ccc2N(C(=O)CSc3ncn[nH]3)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F08 compound treatment 283.4 96.0 0.5 282.1 94.7 0.49 0.702 1.0 1973711 ChemDiv1_007158 OC(=O)CCCNC(=O)c1ccc2OCCOc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F09 compound treatment 299.5 112.0 0.58 296.9 109.0 0.57 0.8158 0.9999 1973712 ChemDiv1_007159 Cc1ccc(cc1)C(=O)N2N=C(CC2c3ccco3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F10 compound treatment 275.8 88.4 0.46 279.3 91.9 0.48 0.6637 0.9998 1973713 ChemDiv1_007160 CCCOC(=O)COc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F11 compound treatment 276.7 89.3 0.47 282.5 95.1 0.49 0.6788 0.9996 1541003 ChemDiv1_007161 COC(=O)c1ccccc1NC(=O)c2ccc3OCCOc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F12 compound treatment 274.8 87.4 0.46 278.2 90.8 0.47 0.6559 0.9998 1973714 ChemDiv1_007162 CCCCOC(=O)COc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F13 compound treatment 279.4 92.0 0.48 279.6 92.2 0.48 0.6781 1.0 1973715 ChemDiv1_007163 Cc1ccc2nc(NC3=NC(CC(=O)N3)c4ccccc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F14 compound treatment 280.3 92.9 0.48 276.9 89.5 0.47 0.6715 0.9998 1133404 ChemDiv1_007164 Brc1ccccc1Oc2coc3cc(OCC(=O)OC4CCCCC4)ccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F15 compound treatment 276.0 88.6 0.46 279.5 92.1 0.48 0.6652 0.9998 1160743 ChemDiv1_007165 Cc1c(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F16 compound treatment 277.8 90.4 0.47 281.7 94.3 0.49 0.6799 0.9998 1505434 ChemDiv1_007166 Cc1cc(C)cc(Oc2coc3cc(OCC(=O)OCc4ccccc4)ccc3c2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F17 compound treatment 276.3 88.9 0.46 279.3 91.9 0.48 0.6655 0.9999 1384618 ChemDiv1_007167 COc1ccc(C)cc1N(CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)S(=O)(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F18 compound treatment 278.8 91.4 0.48 277.2 89.8 0.47 0.667 0.9999 1973716 ChemDiv1_007168 COc1ccc(cc1OC)c2c(oc3cc(OCC(=O)OC(C)C)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F19 compound treatment 276.5 89.1 0.46 276.7 89.3 0.46 0.6567 1.0 1973717 ChemDiv1_007169 CN1C(=O)N(C)C(=O)C(=Cc2cn(Cc3ccccc3C#N)c4ccccc24)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F20 compound treatment 277.9 90.5 0.47 276.6 89.2 0.46 0.6615 1.0 1973718 ChemDiv1_007170 CN(C)CCOC(=O)CCN1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F21 compound treatment 274.7 87.3 0.46 275.3 87.9 0.46 0.6449 1.0 1973719 ChemDiv1_007171 CCSCCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)ccc2OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F22 compound treatment 278.8 91.4 0.48 281.1 93.7 0.49 0.6814 0.9999 1973720 ChemDiv1_007172 C/C(=C\c1ccccc1)/C=C\2/SC(=S)N(CCC(=O)N3CCCc4ccccc34)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F23 mock treatment 280.0 92.6 0.48 279.1 91.7 0.48 0.6784 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 F24 mock treatment 79.3 -108.0 -0.56 80.7 -107.0 -0.55 -0.7911 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G01 compound treatment 283.4 96.0 0.5 286.5 99.1 0.52 0.7182 0.9999 1973721 ChemDiv1_007173 COC(=O)C1=C(N)OC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G02 compound treatment 283.3 95.9 0.5 281.2 93.8 0.49 0.6983 0.9999 1925508 ChemDiv1_007174 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G03 compound treatment 280.8 93.4 0.49 283.3 95.9 0.5 0.6968 0.9999 1973722 ChemDiv1_007175 CCOC(=O)C1=C(N)OC2=C(C1c3cc(ccc3Cl)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G04 compound treatment 281.5 94.1 0.49 278.7 91.3 0.47 0.6825 0.9999 1973723 ChemDiv1_007176 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccccc3)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G05 compound treatment 281.7 94.3 0.49 282.9 95.5 0.5 0.6987 1.0 1973724 ChemDiv1_007177 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(C)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G06 compound treatment 278.1 90.7 0.47 283.2 95.8 0.5 0.6865 0.9997 1784109 ChemDiv1_007178 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G07 compound treatment 281.5 94.1 0.49 278.0 90.6 0.47 0.6799 0.9998 1973725 ChemDiv1_007179 COc1ccc(C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G08 compound treatment 280.5 93.1 0.49 281.2 93.8 0.49 0.688 1.0 1128692 ChemDiv1_007180 CC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G09 compound treatment 277.8 90.4 0.47 278.0 90.6 0.47 0.6663 1.0 1383904 ChemDiv1_007181 CCOC(=O)C1=C(N)OC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G10 compound treatment 279.2 91.8 0.48 282.1 94.7 0.49 0.6865 0.9999 1973726 ChemDiv1_007182 Brc1ccc(cc1)C(=O)NC(=S)Nc2ccc3C(=O)c4ccccc4C(=O)c3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G11 compound treatment 274.7 87.3 0.46 279.3 91.9 0.48 0.6596 0.9997 1866051 ChemDiv1_007183 COc1ccc2oc(=O)c(cc2c1)C(=O)N3CCN(C/C=C/c4ccccc4)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G12 compound treatment 276.2 88.8 0.46 279.3 91.9 0.48 0.6652 0.9999 1477833 ChemDiv1_007184 Brc1cccc(c1)c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G13 compound treatment 278.5 91.1 0.48 276.6 89.2 0.46 0.6637 0.9999 1474623 ChemDiv1_007185 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(c2)c3nc4ccc(C)cc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G14 compound treatment 275.5 88.1 0.46 275.6 88.2 0.46 0.649 1.0 1973727 ChemDiv1_007186 COc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G15 compound treatment 278.8 91.4 0.48 281.6 94.2 0.49 0.6832 0.9999 1973728 ChemDiv1_007187 COc1ccc(Cl)cc1N(CC(=O)N2CCc3ccccc3C2)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G16 compound treatment 278.0 90.6 0.47 277.6 90.2 0.47 0.6655 1.0 1578354 ChemDiv1_007188 CCOC(=O)c1nc(Nc2ccc(Cl)cc2C)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G17 compound treatment 357.4 170.0 0.89 357.2 170.0 0.88 1.251 1.0 1077754 ChemDiv1_007189 COC1C(CC2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC2C1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G18 compound treatment 274.3 86.9 0.45 274.4 87.0 0.45 0.6401 1.0 1973729 ChemDiv1_007190 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccccc4)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G19 compound treatment 277.7 90.3 0.47 279.4 92.0 0.48 0.6711 1.0 1422550 ChemDiv1_007191 COc1ccc2cc(C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5)c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G20 compound treatment 276.4 89.0 0.46 278.9 91.5 0.48 0.6644 0.9999 1198963 ChemDiv1_007192 CCOC(=O)c1nc(Nc2ccc(F)c(Cl)c2)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G21 compound treatment 276.8 89.4 0.47 274.9 87.5 0.45 0.6512 0.9999 1661941 ChemDiv1_007193 Cc1cc(O)c(NC(=O)c2ccc3OCCOc3c2)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G22 compound treatment 275.3 87.9 0.46 283.5 96.1 0.5 0.6773 0.9991 1973730 ChemDiv1_007194 [O-][N+](=O)c1ccc2nc(Cc3ccc(Cl)c(c3)[N+](=O)[O-])c(=O)[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G23 mock treatment 276.5 89.1 0.46 280.2 92.8 0.48 0.6696 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 G24 mock treatment 76.4 -111.0 -0.58 81.0 -106.0 -0.55 -0.8007 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H01 compound treatment 279.5 92.1 0.48 284.7 97.3 0.51 0.6972 0.9997 1155020 ChemDiv1_007195 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(OC)cc2OC)S(=O)(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H02 compound treatment 281.3 93.9 0.49 275.7 88.3 0.46 0.6707 0.9995 1275324 ChemDiv1_007196 Cc1c(NC(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H03 compound treatment 307.8 120.0 0.63 301.8 114.0 0.59 0.8644 0.9996 1973731 ChemDiv1_007197 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCCc3ccccn3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H04 compound treatment 280.4 93.0 0.48 284.8 97.4 0.51 0.7009 0.9998 1574991 ChemDiv1_007198 Cc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H05 compound treatment 300.6 113.0 0.59 295.0 108.0 0.56 0.8129 0.9996 1973732 ChemDiv1_007199 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)Nc4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H06 compound treatment 277.9 90.5 0.47 277.9 90.5 0.47 0.6663 1.0 1973733 ChemDiv1_007200 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H07 compound treatment 280.1 92.7 0.48 282.0 94.6 0.49 0.6895 1.0 1973734 ChemDiv1_007201 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H08 compound treatment 282.6 95.2 0.5 279.7 92.3 0.48 0.6902 0.9999 1727639 ChemDiv1_007202 O=C(Nc1ccc2oc(nc2c1)c3cccnc3)c4cccc(OCc5ccccc5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H09 compound treatment 277.0 89.6 0.47 280.3 92.9 0.48 0.6718 0.9999 1973735 ChemDiv1_007203 O=C(CSc1ncn(n1)c2ccccc2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H10 compound treatment 279.8 92.4 0.48 276.2 88.8 0.46 0.667 0.9998 1973736 ChemDiv1_007204 CC(C)OC(=O)COc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H11 compound treatment 276.4 89.0 0.46 278.7 91.3 0.47 0.6637 0.9999 1117660 ChemDiv1_007205 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N=c3ssc4c3-c5ccccc5NC4(C)C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H12 compound treatment 274.2 86.8 0.45 277.7 90.3 0.47 0.6519 0.9998 1973737 ChemDiv1_007206 COc1ccc(Oc2c(oc3cc(OCC(=O)OC(C)C)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H13 compound treatment 276.9 89.5 0.47 280.2 92.8 0.48 0.671 0.9999 1427026 ChemDiv1_007207 COc1ccc(NC2CC(C)N(C(=O)c3ccccc3)c4ccc(OC)cc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H14 compound treatment 277.6 90.2 0.47 277.4 90.0 0.47 0.6633 1.0 1196575 ChemDiv1_007208 CCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H15 compound treatment 280.3 92.9 0.48 277.1 89.7 0.47 0.6722 0.9998 1461196 ChemDiv1_007209 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(OC)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H16 compound treatment 280.8 93.4 0.49 280.6 93.2 0.48 0.6869 1.0 1973738 ChemDiv1_007210 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cc(C)cc(C)c3)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H17 compound treatment 278.0 90.6 0.47 278.8 91.4 0.48 0.67 1.0 1239430 ChemDiv1_007211 CS(=O)(=O)N(CC(=O)N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H18 compound treatment 277.3 89.9 0.47 277.8 90.4 0.47 0.6637 1.0 1973739 ChemDiv1_007212 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H19 compound treatment 284.5 97.1 0.51 279.8 92.4 0.48 0.6976 0.9997 1191409 ChemDiv1_007213 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(o3)N4CCOCC4)c(=O)n2C1c5ccccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H20 compound treatment 275.5 88.1 0.46 277.1 89.7 0.47 0.6545 1.0 1973740 ChemDiv1_007214 OC(=O)c1ccccc1NC(=O)CCN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H21 compound treatment 278.1 90.7 0.47 279.6 92.2 0.48 0.6733 1.0 1298106 ChemDiv1_007215 COc1ccc(cc1OCc2ccccc2)C3NC(=O)NC(=C3C(=O)OCC4CCCO4)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H22 compound treatment 288.3 101.0 0.53 283.9 96.5 0.5 0.7267 0.9997 1973741 ChemDiv1_007216 C/C(=C\c1ccccc1)/C=C\2/SC(=S)N(CCC(=O)NCCCN3CCOCC3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H23 mock treatment 279.4 92.0 0.48 279.6 92.2 0.48 0.6781 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 H24 mock treatment 76.4 -111.0 -0.58 79.1 -108.0 -0.56 -0.8077 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I01 compound treatment 284.8 97.4 0.51 286.2 98.8 0.51 0.7222 1.0 1973742 ChemDiv1_007217 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I02 compound treatment 283.8 96.4 0.5 284.7 97.3 0.51 0.713 1.0 1410569 ChemDiv1_007218 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I03 compound treatment 283.9 96.5 0.5 282.6 95.2 0.49 0.7057 1.0 1973743 ChemDiv1_007219 COC(=O)C1=C(N)OC2=C(C1c3cc(ccc3Cl)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I04 compound treatment 282.4 95.0 0.5 281.5 94.1 0.49 0.6961 1.0 1973744 ChemDiv1_007220 Cc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I05 compound treatment 281.8 94.4 0.49 280.1 92.7 0.48 0.6888 0.9999 1973745 ChemDiv1_007221 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I06 compound treatment 281.6 94.2 0.49 281.0 93.6 0.49 0.6913 1.0 1973746 ChemDiv1_007222 OC(=O)CCC(=O)N1N=C(CC1c2ccc(cc2)[N+](=O)[O-])c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I07 compound treatment 279.2 91.8 0.48 281.2 93.8 0.49 0.6832 1.0 1973747 ChemDiv1_007223 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I08 compound treatment 288.2 101.0 0.53 289.8 102.0 0.53 0.748 1.0 1554236 ChemDiv1_007224 OC(=O)CCC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I09 compound treatment 279.1 91.7 0.48 280.4 93.0 0.48 0.6799 1.0 1973748 ChemDiv1_007225 COC(=O)C1=C(N)OC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I10 compound treatment 278.8 91.4 0.48 278.5 91.1 0.47 0.6718 1.0 1557935 ChemDiv1_007226 CCOc1ccc(Nc2nc(NCc3cccnc3)nc(OC)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I11 compound treatment 276.9 89.5 0.47 281.4 94.0 0.49 0.6755 0.9997 1973749 ChemDiv1_007227 Cc1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I12 compound treatment 282.1 94.7 0.49 281.6 94.2 0.49 0.6954 1.0 1398368 ChemDiv1_007228 Brc1ccccc1c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I13 compound treatment 280.9 93.5 0.49 284.1 96.7 0.5 0.7001 0.9999 1237205 ChemDiv1_007229 Cc1ccc2nc(oc2c1)c3ccc(C)c(NC(=O)c4ccc5OCCOc5c4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I14 compound treatment 279.1 91.7 0.48 283.3 95.9 0.5 0.6906 0.9998 1973750 ChemDiv1_007230 COc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I15 compound treatment 280.3 92.9 0.48 276.8 89.4 0.46 0.6711 0.9998 1553870 ChemDiv1_007231 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I16 compound treatment 280.0 92.6 0.48 277.5 90.1 0.47 0.6726 0.9999 1600380 ChemDiv1_007232 CCOC(=O)c1nc(Nc2ccc(C)c(Cl)c2)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I17 compound treatment 279.8 92.4 0.48 279.2 91.8 0.48 0.6781 1.0 1731452 ChemDiv1_007233 OC(=O)CSc1nc2ccccc2n1c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I18 compound treatment 276.4 89.0 0.46 277.6 90.2 0.47 0.6596 1.0 1973751 ChemDiv1_007234 COc1cc(ccc1NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I19 compound treatment 283.4 96.0 0.5 279.8 92.4 0.48 0.6936 0.9998 1973752 ChemDiv1_007235 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(N4CCN(C)CC4)c(c3)[N+](=O)[O-])/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I20 compound treatment 277.1 89.7 0.47 279.3 91.9 0.48 0.6685 0.9999 1973753 ChemDiv1_007236 COc1cccc(c1)N2CCN(CC2)C(=O)Cn3c4ccccc4c(=O)c5cc(C)ccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I21 compound treatment 278.3 90.9 0.47 279.0 91.6 0.48 0.6718 1.0 1470277 ChemDiv1_007237 O=C(Nc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I22 compound treatment 276.6 89.2 0.47 277.2 89.8 0.47 0.6589 1.0 1973754 ChemDiv1_007238 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(ccc24)[N+](=O)[O-])c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I23 mock treatment 279.5 92.1 0.48 277.5 90.1 0.47 0.6707 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 I24 mock treatment 77.6 -110.0 -0.57 79.8 -108.0 -0.56 -0.8007 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J01 compound treatment 282.8 95.4 0.5 283.5 96.1 0.5 0.7049 1.0 1412864 ChemDiv1_007239 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J02 compound treatment 280.7 93.3 0.49 280.4 93.0 0.48 0.6858 1.0 1973755 ChemDiv1_007240 COc1cc(cc(Br)c1OC)C2Nc3c(cccc3C4C=CCC42)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J03 compound treatment 279.7 92.3 0.48 280.7 93.3 0.48 0.6832 1.0 1973756 ChemDiv1_007241 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCCCn3ccnc3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J04 compound treatment 281.9 94.5 0.49 280.4 93.0 0.48 0.6902 1.0 1191341 ChemDiv1_007242 COc1ccc(N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J05 compound treatment 280.8 93.4 0.49 276.9 89.5 0.47 0.6733 0.9997 1518064 ChemDiv1_007243 Cc1cc2N(C(=O)CSc3ncn[nH]3)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J06 compound treatment 278.6 91.2 0.48 280.2 92.8 0.48 0.6773 1.0 1268622 ChemDiv1_007244 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J07 compound treatment 275.3 87.9 0.46 281.9 94.5 0.49 0.6714 0.9994 1973757 ChemDiv1_007245 CCCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J08 compound treatment 278.9 91.5 0.48 279.6 92.2 0.48 0.6762 1.0 1862876 ChemDiv1_007246 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc3oc(nc3c2)c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J09 compound treatment 278.2 90.8 0.47 280.1 92.7 0.48 0.6755 1.0 1973758 ChemDiv1_007247 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J10 compound treatment 281.3 93.9 0.49 278.3 90.9 0.47 0.6803 0.9998 1973759 ChemDiv1_007248 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J11 compound treatment 274.0 86.6 0.45 280.6 93.2 0.48 0.6618 0.9994 1107300 ChemDiv1_007249 CC(=O)Nc1ccc(Nc2nc(Cl)nc(Nc3ccc(NC(=O)C)cc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J12 compound treatment 276.3 88.9 0.46 280.4 93.0 0.48 0.6696 0.9998 1973760 ChemDiv1_007250 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J13 compound treatment 278.8 91.4 0.48 274.8 87.4 0.45 0.6582 0.9997 1327797 ChemDiv1_007251 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4cccc(F)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J14 compound treatment 279.4 92.0 0.48 279.2 91.8 0.48 0.6766 1.0 1973761 ChemDiv1_007252 CCCOC(=O)C(CC)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J15 compound treatment 276.5 89.1 0.46 277.7 90.3 0.47 0.6604 1.0 1323438 ChemDiv1_007253 Cc1c(NC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J16 compound treatment 278.4 91.0 0.47 281.5 94.1 0.49 0.6814 0.9999 1973762 ChemDiv1_007254 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3cc(C)cc(C)c3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J17 compound treatment 278.4 91.0 0.47 276.5 89.1 0.46 0.663 0.9999 1195759 ChemDiv1_007255 Fc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J18 compound treatment 269.6 82.2 0.43 272.9 85.5 0.44 0.6173 0.9998 1973763 ChemDiv1_007256 COC(=O)C(C)Oc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J19 compound treatment 304.5 117.0 0.61 301.1 114.0 0.59 0.8497 0.9999 1630356 ChemDiv1_007257 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(o3)N4CCOCC4)c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J20 compound treatment 275.6 88.2 0.46 281.0 93.6 0.49 0.6692 0.9996 1973764 ChemDiv1_007258 OC(=O)c1cccc(NC(=O)CCN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J21 compound treatment 277.1 89.7 0.47 278.3 90.9 0.47 0.6648 1.0 1923259 ChemDiv1_007259 CC1=C(C(NC(=O)N1)c2ccc(O)c(c2)[N+](=O)[O-])C(=O)OCc3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J22 compound treatment 287.1 99.7 0.52 287.0 99.6 0.52 0.7337 1.0 1973765 ChemDiv1_007260 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C\C(=C\c3ccccc3)\C)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J23 mock treatment 278.6 91.2 0.48 280.4 93.0 0.48 0.6781 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 J24 mock treatment 77.2 -110.0 -0.58 78.3 -109.0 -0.57 -0.8077 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K01 compound treatment 284.9 97.5 0.51 289.3 102.0 0.53 0.734 0.9998 1973766 ChemDiv1_007261 COC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K02 compound treatment 277.2 89.8 0.47 282.5 95.1 0.49 0.6806 0.9996 1134909 ChemDiv1_007262 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K03 compound treatment 279.7 92.3 0.48 282.2 94.8 0.49 0.6887 0.9999 1973767 ChemDiv1_007263 COC(=O)C1=C(N)OC2=C(C1c3cccc(Cl)c3Cl)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K04 compound treatment 282.6 95.2 0.5 283.8 96.4 0.5 0.7053 1.0 1973768 ChemDiv1_007264 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K05 compound treatment 284.7 97.3 0.51 280.7 93.3 0.48 0.7017 0.9997 1973769 ChemDiv1_007265 COC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K06 compound treatment 279.6 92.2 0.48 282.2 94.8 0.49 0.6884 0.9999 1307671 ChemDiv1_007266 OC1(CC(=O)c2ccncc2)C(=O)Nc3ccc(Br)cc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K07 compound treatment 281.5 94.1 0.49 282.4 95.0 0.49 0.6961 1.0 1973770 ChemDiv1_007267 COc1cc(ccc1OCc2ccccc2)C3C(=C(N)OC4=C3C(=O)CC(C4)c5ccccc5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K08 compound treatment 279.2 91.8 0.48 280.5 93.1 0.48 0.6806 1.0 1973771 ChemDiv1_007268 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K09 compound treatment 280.9 93.5 0.49 279.5 92.1 0.48 0.6832 1.0 1973772 ChemDiv1_007269 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OCC)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K10 compound treatment 275.5 88.1 0.46 279.6 92.2 0.48 0.6637 0.9998 1379264 ChemDiv1_007270 O=c1oc(nc2sc3CCCCCc3c12)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K11 compound treatment 276.3 88.9 0.46 281.9 94.5 0.49 0.6751 0.9996 1973773 ChemDiv1_007271 Cn1nc(Cl)c2ccccc2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K12 compound treatment 279.3 91.9 0.48 282.8 95.4 0.5 0.6895 0.9999 1973774 ChemDiv1_007272 Clc1ccc2n(CC(=O)Nc3cc(Cl)cc(Cl)c3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K13 compound treatment 278.0 90.6 0.47 277.5 90.1 0.47 0.6652 1.0 1163466 ChemDiv1_007273 COc1ccc(cc1Br)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K14 compound treatment 275.5 88.1 0.46 280.2 92.8 0.48 0.6659 0.9997 1973775 ChemDiv1_007274 Cc1ccc2n(CC(=O)Nc3ccc(Oc4ccc(Cl)cc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K15 compound treatment 274.3 86.9 0.45 280.3 92.9 0.48 0.6618 0.9995 1313953 ChemDiv1_007275 CCOc1ccccc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K16 compound treatment 280.4 93.0 0.48 278.1 90.7 0.47 0.6762 0.9999 1973776 ChemDiv1_007276 Cc1ccc2n(CC(=O)Nc3c(F)cc(F)cc3Br)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K17 compound treatment 277.6 90.2 0.47 281.6 94.2 0.49 0.6788 0.9998 1142110 ChemDiv1_007277 CN(C)c1nc(N)c2n(C)cnc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K18 compound treatment 277.3 89.9 0.47 280.3 92.9 0.48 0.6729 0.9999 1973777 ChemDiv1_007278 Cc1ccc2n(CC(=O)Nc3cc(Sc4ccc(F)cc4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K19 compound treatment 281.1 93.7 0.49 279.8 92.4 0.48 0.6851 1.0 1489299 ChemDiv1_007279 CCC(C)n1c(SCSc2nc3n(C)c(=O)n(C)c(=O)c3n2C(C)CC)nc4n(C)c(=O)n(C)c(=O)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K20 compound treatment 279.2 91.8 0.48 281.5 94.1 0.49 0.6843 0.9999 1350373 ChemDiv1_007280 CCOC(=O)c1nc(Nc2ccc(OC)cc2OC)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K21 compound treatment 279.8 92.4 0.48 278.7 91.3 0.47 0.6762 1.0 1973778 ChemDiv1_007281 BrCc1ccc2c(c1)c(nc3nnnn32)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K22 compound treatment 278.7 91.3 0.48 278.1 90.7 0.47 0.67 1.0 1973779 ChemDiv1_007282 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(ccc24)[N+](=O)[O-])cc1F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K23 mock treatment 280.8 93.4 0.49 279.6 92.2 0.48 0.6832 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 K24 mock treatment 80.6 -107.0 -0.56 68.7 -119.0 -0.62 -0.8304 -0.9987 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L01 compound treatment 283.6 96.2 0.5 278.5 91.1 0.47 0.6895 0.9996 1973780 ChemDiv1_007283 COc1ccc(N(CC(=O)Nc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L02 compound treatment 280.1 92.7 0.48 283.6 96.2 0.5 0.6953 0.9999 1973781 ChemDiv1_007284 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc3OCOc3c2)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L03 compound treatment 280.1 92.7 0.48 280.1 92.7 0.48 0.6825 1.0 1973782 ChemDiv1_007285 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCc3ccccn3)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L04 compound treatment 283.7 96.3 0.5 282.3 94.9 0.49 0.7038 1.0 1590166 ChemDiv1_007286 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)S(=O)(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L05 compound treatment 281.6 94.2 0.49 282.6 95.2 0.49 0.6972 1.0 1264058 ChemDiv1_007287 CCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L06 compound treatment 278.4 91.0 0.47 281.5 94.1 0.49 0.6814 0.9999 1973783 ChemDiv1_007288 [O-][N+](=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L07 compound treatment 283.6 96.2 0.5 281.4 94.0 0.49 0.7002 0.9999 1652038 ChemDiv1_007289 COc1ccccc1Nc2nc(Nc3ccccc3OC)nc(n2)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L08 compound treatment 275.8 88.4 0.46 276.9 89.5 0.47 0.6549 1.0 1973784 ChemDiv1_007290 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3c4ccc(cc4)C(F)(F)F)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L09 compound treatment 276.6 89.2 0.47 278.7 91.3 0.47 0.6644 0.9999 1218009 ChemDiv1_007291 CCOC(=O)c1sc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L10 compound treatment 278.0 90.6 0.47 276.3 88.9 0.46 0.6608 0.9999 1973785 ChemDiv1_007292 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4cccc(C)c4)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L11 compound treatment 273.4 86.0 0.45 276.1 88.7 0.46 0.6431 0.9999 1973786 ChemDiv1_007293 COC(=O)c1cc(=O)n2ncnc2[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L12 compound treatment 276.1 88.7 0.46 279.1 91.7 0.48 0.6641 0.9999 1167132 ChemDiv1_007294 CC(C)OC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L13 compound treatment 278.2 90.8 0.47 280.9 93.5 0.49 0.6784 0.9999 1653457 ChemDiv1_007295 COc1ccc2nc(SCC(=O)N3c4ccccc4C(=CC3(C)C)C)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L14 compound treatment 286.2 98.8 0.52 287.1 99.7 0.52 0.7307 1.0 1494294 ChemDiv1_007296 CCCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L15 compound treatment 278.1 90.7 0.47 278.0 90.6 0.47 0.6674 1.0 1462483 ChemDiv1_007297 COc1cc(cc(Br)c1OC)C2Nc3c(OC)ccc(Cl)c3C4C=CCC42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L16 compound treatment 281.7 94.3 0.49 273.0 85.6 0.44 0.6623 0.9988 1208479 ChemDiv1_007298 COc1ccccc1c2coc3cc(OC(C)C(=O)OCc4ccccc4)ccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L17 compound treatment 278.0 90.6 0.47 274.0 86.6 0.45 0.6523 0.9997 1973787 ChemDiv1_007299 [O-][N+](=O)c1cccc(c1)N(CC(=O)N2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L18 compound treatment 280.3 92.9 0.48 275.6 88.2 0.46 0.6667 0.9996 1973788 ChemDiv1_007300 CCOCCOC(=O)COc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L19 compound treatment 290.6 103.0 0.54 285.4 98.0 0.51 0.7407 0.9996 1248076 ChemDiv1_007301 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4n(C)c(=O)n(C)c4c3)c(=O)n2C1c5ccc(cc5)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L20 compound treatment 276.5 89.1 0.46 276.6 89.2 0.46 0.6563 1.0 1973789 ChemDiv1_007302 OC(=O)c1ccc(NC(=O)CCN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L21 compound treatment 276.0 88.6 0.46 277.0 89.6 0.47 0.656 1.0 1158641 ChemDiv1_007303 CCOc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OC(C)CC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L22 compound treatment 295.6 108.0 0.56 292.5 105.0 0.55 0.7852 0.9999 1973790 ChemDiv1_007304 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCC(=O)Nc3cc(C)on3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L23 mock treatment 278.5 91.1 0.48 283.5 96.1 0.5 0.6891 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 L24 mock treatment 78.7 -109.0 -0.57 78.8 -109.0 -0.56 -0.8003 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M01 compound treatment 283.6 96.2 0.5 285.9 98.5 0.51 0.7167 0.9999 1973791 ChemDiv1_007305 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M02 compound treatment 277.7 90.3 0.47 281.2 93.8 0.49 0.6777 0.9998 1480715 ChemDiv1_007306 COc1ccc(cc1)C2=NN(C(C2)c3cc(OC)ccc3OC)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M03 compound treatment 279.7 92.3 0.48 282.2 94.8 0.49 0.6887 0.9999 1973792 ChemDiv1_007307 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3C)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M04 compound treatment 295.8 108.0 0.57 302.5 115.0 0.6 0.8227 0.9996 1321881 ChemDiv1_007308 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M05 compound treatment 280.1 92.7 0.48 281.0 93.6 0.49 0.6858 1.0 1973793 ChemDiv1_007309 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M06 compound treatment 275.4 88.0 0.46 280.4 93.0 0.48 0.6662 0.9997 1126212 ChemDiv1_007310 Cc1ccc(cc1)C2=NN(C(C2)c3cc4cccc(C)c4nc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M07 compound treatment 281.5 94.1 0.49 285.1 97.7 0.51 0.706 0.9999 1973794 ChemDiv1_007311 COc1cc(cc(OC)c1OC)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M08 compound treatment 280.8 93.4 0.49 279.4 92.0 0.48 0.6825 1.0 1562888 ChemDiv1_007312 CC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M09 compound treatment 278.4 91.0 0.47 278.6 91.2 0.47 0.6707 1.0 1973795 ChemDiv1_007313 CCOc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M10 compound treatment 275.9 88.5 0.46 277.4 90.0 0.47 0.6571 1.0 1663889 ChemDiv1_007314 Cc1cccc(c1)c2nc3sc4CCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M11 compound treatment 285.0 97.6 0.51 281.9 94.5 0.49 0.7072 0.9998 1973796 ChemDiv1_007315 CCOC(=O)Cn1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3Cl)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M12 compound treatment 282.8 95.4 0.5 282.6 95.2 0.49 0.7016 1.0 1151782 ChemDiv1_007316 Cc1cc2nc(Cc3cc(Br)ccc3F)c(=O)[nH]c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M13 compound treatment 282.7 95.3 0.5 281.9 94.5 0.49 0.6987 1.0 1718008 ChemDiv1_007317 Brc1ccc(cc1)c2ccc(COC(=O)c3ccc4OCCOc4c3)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M14 compound treatment 283.2 95.8 0.5 281.9 94.5 0.49 0.7005 1.0 1973797 ChemDiv1_007318 Cc1ccc2n(CC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M15 compound treatment 274.5 87.1 0.45 279.7 92.3 0.48 0.6604 0.9996 1973798 ChemDiv1_007319 COc1ccc(cc1OC)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M16 compound treatment 277.2 89.8 0.47 278.0 90.6 0.47 0.6641 1.0 1973799 ChemDiv1_007320 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccccc4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M17 compound treatment 282.5 95.1 0.5 279.8 92.4 0.48 0.6902 0.9999 1973800 ChemDiv1_007321 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M18 compound treatment 279.3 91.9 0.48 277.6 90.2 0.47 0.6703 0.9999 1973801 ChemDiv1_007322 Cc1ccc2n(CC(=O)Nc3ccccc3Br)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M19 compound treatment 282.9 95.5 0.5 278.5 91.1 0.47 0.6869 0.9997 1973802 ChemDiv1_007323 CC(C)c1ccc(/C=C/2\Sc3ccccc3C2=O)cc1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M20 compound treatment 276.5 89.1 0.46 277.7 90.3 0.47 0.6604 1.0 1413519 ChemDiv1_007324 CCOC(=O)c1nc(Nc2cc(Cl)ccc2OC)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M21 compound treatment 277.8 90.4 0.47 276.9 89.5 0.47 0.6622 1.0 1190231 ChemDiv1_007325 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M22 compound treatment 278.3 90.9 0.47 272.9 85.5 0.44 0.6494 0.9995 1973803 ChemDiv1_007326 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M23 mock treatment 279.7 92.3 0.48 281.0 93.6 0.49 0.6843 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 M24 mock treatment 186.3 -1.14 -0.01 187.1 -0.309 0.0 -0.0053 -0.8671 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N01 compound treatment 285.7 98.3 0.51 281.1 93.7 0.49 0.7068 0.9997 1207022 ChemDiv1_007327 CCOc1ccc(cc1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N02 compound treatment 280.8 93.4 0.49 281.5 94.1 0.49 0.6902 1.0 1345286 ChemDiv1_007328 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N03 compound treatment 283.0 95.6 0.5 285.7 98.3 0.51 0.7138 0.9999 1973804 ChemDiv1_007329 COCCN/C=C\1/C(=O)N(N=C1CSc2ccc(Cl)cc2)c3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N04 compound treatment 284.4 97.0 0.51 282.9 95.5 0.5 0.7086 1.0 1610755 ChemDiv1_007330 Cc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)S(=O)(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N05 compound treatment 280.0 92.6 0.48 280.9 93.5 0.49 0.6851 1.0 1231335 ChemDiv1_007331 COc1ccc(OC)c(Nc2nc(Cl)nc(Nc3cc(OC)ccc3OC)n2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N06 compound treatment 280.3 92.9 0.48 282.6 95.2 0.49 0.6924 0.9999 1152306 ChemDiv1_007332 CC(NC(=O)c1ccc2OCCOc2c1)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N07 compound treatment 279.4 92.0 0.48 278.6 91.2 0.47 0.6744 1.0 1973805 ChemDiv1_007333 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N08 compound treatment 282.8 95.4 0.5 280.4 93.0 0.48 0.6935 0.9999 1199748 ChemDiv1_007334 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CN3C(=O)c4ccccc4C3=O)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N09 compound treatment 280.1 92.7 0.48 283.7 96.3 0.5 0.6957 0.9998 1973806 ChemDiv1_007335 Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N10 compound treatment 276.1 88.7 0.46 275.8 88.4 0.46 0.6519 1.0 1973807 ChemDiv1_007336 CCOCCOC(=O)COc1ccc2c(=O)c(c3cccc4ccccc34)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N11 compound treatment 288.4 101.0 0.53 286.7 99.3 0.52 0.7374 0.9999 1566144 ChemDiv1_007337 COc1ccc2nc(SC(=O)c3ccccc3Cl)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N12 compound treatment 280.1 92.7 0.48 280.1 92.7 0.48 0.6825 1.0 1973808 ChemDiv1_007338 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N13 compound treatment 280.6 93.2 0.49 278.2 90.8 0.47 0.6773 0.9999 1602963 ChemDiv1_007339 COc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c4ccc(C)cc4n3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N14 compound treatment 277.7 90.3 0.47 280.0 92.6 0.48 0.6733 0.9999 1973809 ChemDiv1_007340 CCCCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N15 compound treatment 277.0 89.6 0.47 280.8 93.4 0.49 0.6736 0.9998 1615587 ChemDiv1_007341 COc1ccc(cc1Br)S(=O)(=O)N(CC(=O)NCc2ccncc2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N16 compound treatment 277.6 90.2 0.47 282.2 94.8 0.49 0.681 0.9997 1973810 ChemDiv1_007342 COc1ccccc1c2c(oc3cc(OCC(=O)OC(C)C)ccc3c2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N17 compound treatment 275.6 88.2 0.46 278.9 91.5 0.48 0.6615 0.9999 1658351 ChemDiv1_007343 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N18 compound treatment 277.5 90.1 0.47 279.3 91.9 0.48 0.67 1.0 1342406 ChemDiv1_007344 Clc1ccccc1c2nc(NCc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N19 compound treatment 274.8 87.4 0.46 278.6 91.2 0.47 0.6574 0.9998 1399989 ChemDiv1_007345 COc1cc(ccc1OCc2ccccc2)C3NC(=O)NC(=C3C(=O)OCC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N20 compound treatment 277.7 90.3 0.47 281.5 94.1 0.49 0.6788 0.9998 1973811 ChemDiv1_007346 Brc1cccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccccn3)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N21 compound treatment 281.3 93.9 0.49 281.9 94.5 0.49 0.6935 1.0 1417852 ChemDiv1_007347 COc1cc(cc(Cl)c1O)C2NC(=O)NC(=C2C(=O)OCCc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N22 compound treatment 299.7 112.0 0.59 300.0 113.0 0.59 0.8279 1.0 1973812 ChemDiv1_007348 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCC(=O)N(CCO)Cc3ccccc3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N23 mock treatment 280.8 93.4 0.49 275.6 88.2 0.46 0.6685 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 N24 mock treatment 191.2 3.76 0.02 189.7 2.29 0.01 0.0223 0.9714 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O01 compound treatment 285.0 97.6 0.51 284.3 96.9 0.5 0.716 1.0 1973813 ChemDiv1_007349 COC(=O)C1=C(N)OC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O02 compound treatment 281.2 93.8 0.49 278.9 91.5 0.48 0.6821 0.9999 1973814 ChemDiv1_007350 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O03 compound treatment 287.4 100.0 0.52 280.7 93.3 0.48 0.7116 0.9993 1973815 ChemDiv1_007351 COC(=O)C1=C(N)OC2=C(C1c3ccccc3C)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O04 compound treatment 279.3 91.9 0.48 279.0 91.6 0.48 0.6755 1.0 1973816 ChemDiv1_007352 [O-][N+](=O)c1cccc(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O05 compound treatment 278.9 91.5 0.48 283.3 95.9 0.5 0.6898 0.9998 1973817 ChemDiv1_007353 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O06 compound treatment 277.0 89.6 0.47 278.7 91.3 0.47 0.6659 1.0 1615949 ChemDiv1_007354 Cc1cccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(Cl)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O07 compound treatment 279.8 92.4 0.48 281.0 93.6 0.49 0.6847 1.0 1973818 ChemDiv1_007355 CCOC(=O)C1=C(N)OC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O08 compound treatment 278.2 90.8 0.47 281.5 94.1 0.49 0.6806 0.9999 1539017 ChemDiv1_007356 Cc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccccc4)c5ccccc5)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O09 compound treatment 274.5 87.1 0.45 277.7 90.3 0.47 0.653 0.9999 1973819 ChemDiv1_007357 CCOC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O10 compound treatment 277.6 90.2 0.47 278.3 90.9 0.47 0.6666 1.0 1932431 ChemDiv1_007358 Cc1ccc(cc1)c2nc3sc4CCCCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O11 compound treatment 312.3 125.0 0.65 309.8 122.0 0.64 0.9104 0.9999 1973820 ChemDiv1_007359 Brc1ccc(cc1)N2C(=N)S/C(=C\c3ccc(cc3)N4CCOCC4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O12 compound treatment 276.3 88.9 0.46 280.8 93.4 0.49 0.671 0.9997 1339205 ChemDiv1_007360 CCOC(=O)c1nc(Nc2cc(OC)cc(OC)c2)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O13 compound treatment 283.8 96.4 0.5 287.1 99.7 0.52 0.7219 0.9999 1443971 ChemDiv1_007361 CCOc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O14 compound treatment 277.8 90.4 0.47 277.2 89.8 0.47 0.6633 1.0 1973821 ChemDiv1_007362 Cc1ccc2n(CC(=O)Nc3ccc(F)cc3Cl)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O15 compound treatment 277.5 90.1 0.47 275.4 88.0 0.46 0.6556 0.9999 1406723 ChemDiv1_007363 Cc1c(NC(=O)CN(c2ccccc2F)S(=O)(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O16 compound treatment 278.2 90.8 0.47 281.9 94.5 0.49 0.6821 0.9998 1973822 ChemDiv1_007364 CCOC(=O)N1CCC(CC1)NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O17 compound treatment 345.4 158.0 0.82 350.2 163.0 0.85 1.181 0.9999 1973823 ChemDiv1_007365 CC(=O)/N=C/1\NC(=O)\C(=C\c2c(C)n(Cc3ccc(F)cc3)c4ccccc24)\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O18 compound treatment 282.5 95.1 0.5 278.9 91.5 0.48 0.6869 0.9998 1973824 ChemDiv1_007366 Cc1ccc2n(CC(=O)Nc3c(C)cc(Br)cc3C)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O19 compound treatment 275.0 87.6 0.46 276.7 89.3 0.46 0.6512 1.0 1973825 ChemDiv1_007367 COc1ccc(cc1)N2C(=N)S/C(=C\c3ccccc3[N+](=O)[O-])/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O20 compound treatment 278.6 91.2 0.48 277.6 90.2 0.47 0.6678 1.0 1672328 ChemDiv1_007368 CCOC(=O)c1nc(Nc2cc(Cl)c(OC)cc2OC)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O21 compound treatment 280.3 92.9 0.48 278.8 91.4 0.48 0.6784 1.0 1210895 ChemDiv1_007369 Cc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O22 compound treatment 274.5 87.1 0.45 278.4 91.0 0.47 0.6556 0.9998 1973826 ChemDiv1_007370 [O-][N+](=O)c1ccc2n(CC(=O)Nc3cccc(Cl)c3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O23 mock treatment 280.1 92.7 0.48 280.9 93.5 0.49 0.6854 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 O24 mock treatment 107.4 -80.0 -0.42 105.6 -81.8 -0.43 -0.5959 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P01 compound treatment 283.1 95.7 0.5 287.2 99.8 0.52 0.7196 0.9998 1133791 ChemDiv1_007371 COc1ccc(OC)c(NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P02 compound treatment 284.0 96.6 0.5 281.5 94.1 0.49 0.702 0.9999 1628366 ChemDiv1_007372 Fc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P03 compound treatment 286.0 98.6 0.51 282.5 95.1 0.49 0.7131 0.9998 1973827 ChemDiv1_007373 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCc3ccc4OCOc4c3)c5nc6ccccc6s5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P04 compound treatment 285.0 97.6 0.51 288.8 101.0 0.53 0.7325 0.9998 1675971 ChemDiv1_007374 CCc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P05 compound treatment 279.6 92.2 0.48 285.9 98.5 0.51 0.702 0.9995 1973828 ChemDiv1_007375 CCCCCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P06 compound treatment 283.3 95.9 0.5 282.0 94.6 0.49 0.7013 1.0 1359614 ChemDiv1_007376 OC(=O)CNC(=O)c1ccc2OCCOc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P07 compound treatment 275.1 87.7 0.46 283.3 95.9 0.5 0.6758 0.9991 1926191 ChemDiv1_007377 OC(=O)CCC(=O)N1N=C(CC1c2ccc(Br)cc2)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P08 compound treatment 280.0 92.6 0.48 281.9 94.5 0.49 0.6887 1.0 1332575 ChemDiv1_007378 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(F)c3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P09 compound treatment 279.9 92.5 0.48 281.9 94.5 0.49 0.6884 1.0 1870264 ChemDiv1_007379 OC(COc1ccc(cc1)[N+](=O)[O-])CN2C(=O)c3ccccc3S2(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P10 compound treatment 279.6 92.2 0.48 283.5 96.1 0.5 0.6931 0.9998 1658293 ChemDiv1_007380 COc1ccc(Oc2coc3cc(OC(C)C(=O)OC4CCCCC4)ccc3c2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P11 compound treatment 277.8 90.4 0.47 280.5 93.1 0.48 0.6755 0.9999 1241722 ChemDiv1_007381 Cn1cnc(SCC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P12 compound treatment 281.7 94.3 0.49 283.4 96.0 0.5 0.7005 1.0 1973829 ChemDiv1_007382 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P13 compound treatment 278.5 91.1 0.48 282.0 94.6 0.49 0.6836 0.9999 1973830 ChemDiv1_007383 CC(=O)NS(=O)(=O)c1ccc(cc1)N2C(=O)CC(Sc3nc4ccccc4s3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P14 compound treatment 279.3 91.9 0.48 282.5 95.1 0.49 0.6884 0.9999 1973831 ChemDiv1_007384 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P15 compound treatment 280.3 92.9 0.48 278.0 90.6 0.47 0.6755 0.9999 1522436 ChemDiv1_007385 CC(C)c1ccc(cc1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P16 compound treatment 276.5 89.1 0.46 280.2 92.8 0.48 0.6696 0.9998 1973832 ChemDiv1_007386 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(c3ccccc3OC)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P17 compound treatment 278.1 90.7 0.47 282.6 95.2 0.49 0.6843 0.9997 1973833 ChemDiv1_007387 COc1ccccc1/C=C\2/SC(=O)N(CCNC3=NS(=O)(=O)c4ccccc34)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P18 compound treatment 280.0 92.6 0.48 279.5 92.1 0.48 0.6799 1.0 1699297 ChemDiv1_007388 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P19 compound treatment 277.3 89.9 0.47 282.1 94.7 0.49 0.6795 0.9997 1936004 ChemDiv1_007389 CCOC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OCC)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P20 compound treatment 281.4 94.0 0.49 280.6 93.2 0.48 0.6891 1.0 1973834 ChemDiv1_007390 Brc1cccc(/C=C/2\SC(=S)N(CCC(=O)Nc3nccs3)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P21 compound treatment 287.4 100.0 0.52 287.5 100.0 0.52 0.7366 1.0 1973835 ChemDiv1_007391 Cc1ccccc1CNC(=O)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P22 compound treatment 278.6 91.2 0.48 277.8 90.4 0.47 0.6685 1.0 1973836 ChemDiv1_007392 CCOc1ccc(/C=C/2\SC(=S)N(CCCC(=O)N(CCO)Cc3ccccc3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P23 mock treatment 279.7 92.3 0.48 280.4 93.0 0.48 0.6821 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.607 P24 mock treatment 98.5 -88.9 -0.46 97.5 -89.9 -0.47 -0.6585 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A01 compound treatment 281.9 94.7 0.49 285.8 101.0 0.53 0.7221 0.9995 1973837 ChemDiv1_007393 CCOc1ccc(/C=C/2\SC(=S)N(CCCC(=O)N(CCO)c3ccccc3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A02 compound treatment 279.6 92.4 0.48 280.9 96.5 0.5 0.6956 0.9998 1973838 ChemDiv1_007394 COc1cc(NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A03 compound treatment 282.9 95.7 0.5 278.9 94.5 0.49 0.7004 1.0 1973839 ChemDiv1_007395 Cc1ccc(NC(=O)CC2S/C(=N/c3ccccc3)/N(C2=O)S(=O)(=O)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A04 compound treatment 280.4 93.2 0.49 276.1 91.7 0.48 0.6809 1.0 1362513 ChemDiv1_007396 Cc1cccc(c1)c2nc3ccccc3c(=O)n2CC(=O)N4CCN(CC4)c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A05 compound treatment 279.2 92.0 0.48 280.3 95.9 0.5 0.6919 0.9998 1494739 ChemDiv1_007397 COc1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A06 compound treatment 279.4 92.2 0.48 277.0 92.6 0.48 0.6805 1.0 1268406 ChemDiv1_007398 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(CC)s3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A07 compound treatment 277.9 90.7 0.47 273.9 89.5 0.47 0.6636 1.0 1732790 ChemDiv1_007399 Brc1ccc(cc1)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A08 compound treatment 277.4 90.2 0.47 277.8 93.4 0.49 0.6761 0.9999 1973840 ChemDiv1_007400 CCN(CC)CCOC(=O)c1ccc2OCCOc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A09 compound treatment 279.3 92.1 0.48 272.7 88.3 0.46 0.6644 0.9997 1690704 ChemDiv1_007401 COc1cc(cc(OC)c1OC)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A10 compound treatment 276.8 89.6 0.47 271.1 86.7 0.45 0.6493 0.9998 1973841 ChemDiv1_007402 Cc1cccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(=O)[nH]c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A11 compound treatment 276.4 89.2 0.47 275.1 90.7 0.47 0.6625 1.0 1610980 ChemDiv1_007403 CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A12 compound treatment 275.5 88.3 0.46 273.5 89.1 0.46 0.6533 1.0 1973842 ChemDiv1_007404 COc1ccccc1C2=NN(C(C2)c3ccccc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A13 compound treatment 279.7 92.5 0.48 275.6 91.2 0.47 0.6765 1.0 1396807 ChemDiv1_007405 CCOc1ccc2N(C(=O)CSc3nc4ccccc4o3)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A14 compound treatment 286.4 99.2 0.52 288.4 104.0 0.54 0.7483 0.9998 1973843 ChemDiv1_007406 Fc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A15 compound treatment 280.6 93.4 0.49 278.9 94.5 0.49 0.6919 1.0 1973844 ChemDiv1_007407 Cc1ccc(OCCOc2ccc(cc2c3nc4sc5CCCCc5c4c(=O)[nH]3)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A16 compound treatment 277.5 90.3 0.47 273.3 88.9 0.46 0.6599 1.0 1641522 ChemDiv1_007408 OC1(C2CCCCC2=O)C(=O)Nc3ccc(Br)cc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A17 compound treatment 276.8 89.6 0.47 277.7 93.3 0.49 0.6735 0.9998 1973845 ChemDiv1_007409 CCOc1cc(ccc1OCCOCCOc2ccc(C)c(C)c2)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A18 compound treatment 275.3 88.1 0.46 272.0 87.6 0.46 0.647 1.0 1973846 ChemDiv1_007410 CCC1=NN(C(=O)c2ccc(cc2)c3ccccc3)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A19 compound treatment 274.0 86.8 0.45 275.2 90.8 0.47 0.654 0.9998 1192276 ChemDiv1_007411 COc1ccc(C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A20 compound treatment 281.1 93.9 0.49 272.6 88.2 0.46 0.6706 0.9995 1973847 ChemDiv1_007412 CCCCC1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A21 compound treatment 277.5 90.3 0.47 275.0 90.6 0.47 0.6662 1.0 1973848 ChemDiv1_007413 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(F)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A22 compound treatment 277.8 90.6 0.47 272.0 87.6 0.46 0.6563 0.9998 1951149 ChemDiv1_007414 CC1=NN(C(=O)CCc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A23 mock treatment 276.2 89.0 0.46 279.1 94.7 0.49 0.6764 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 A24 mock treatment 76.9 -110.0 -0.58 73.3 -111.0 -0.58 -0.8151 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B01 compound treatment 280.3 93.1 0.49 280.8 96.4 0.5 0.6978 0.9999 1425008 ChemDiv1_007415 CCOC(=O)C1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B02 compound treatment 281.7 94.5 0.49 277.7 93.3 0.49 0.6916 1.0 1189334 ChemDiv1_007416 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCCOc4c3)c(=O)n2C1c5ccc(OC)c(OCC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B03 compound treatment 277.0 89.8 0.47 274.3 89.9 0.47 0.6618 1.0 1973849 ChemDiv1_007417 Cc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B04 compound treatment 279.0 91.8 0.48 278.8 94.4 0.49 0.6857 0.9999 1260710 ChemDiv1_007418 NNC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B05 compound treatment 275.5 88.3 0.46 275.6 91.2 0.47 0.661 0.9999 1929100 ChemDiv1_007419 CCCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B06 compound treatment 283.6 96.4 0.5 272.2 87.8 0.46 0.6784 0.9988 1267335 ChemDiv1_007420 OC(=O)c1cccnc1SC2CC(=O)N(C2=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B07 compound treatment 283.0 95.8 0.5 282.4 98.0 0.51 0.7137 1.0 1929004 ChemDiv1_007421 OC1(CC(=NN1C(=O)c2ccncc2)c3ccc(Cl)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B08 compound treatment 279.4 92.2 0.48 275.0 90.6 0.47 0.6732 0.9999 1127121 ChemDiv1_007422 O=C(CN1C(=O)c2ccccc2S1(=O)=O)N3CCCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B09 compound treatment 277.1 89.9 0.47 275.9 91.5 0.48 0.668 1.0 1581989 ChemDiv1_007423 COc1ccc(CC(=O)N2N=C(C)CC2(O)c3ccccc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B10 compound treatment 275.9 88.7 0.46 273.6 89.2 0.46 0.6551 1.0 1639012 ChemDiv1_007424 Cc1sc2nc(c3ccccc3Cl)n(CC(=O)Nc4ccc(Oc5ccccc5)cc4)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B11 compound treatment 276.3 89.1 0.46 274.4 90.0 0.47 0.6595 1.0 1483209 ChemDiv1_007425 CCC1=NN(C(=O)c2cccc(C)c2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B12 compound treatment 275.0 87.8 0.46 273.5 89.1 0.46 0.6514 1.0 1537413 ChemDiv1_007426 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2Cc5csc(n5)c6ccc(Cl)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B13 compound treatment 274.3 87.1 0.45 273.2 88.8 0.46 0.6478 1.0 1928954 ChemDiv1_007427 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B14 compound treatment 277.9 90.7 0.47 271.9 87.5 0.45 0.6563 0.9998 1148077 ChemDiv1_007428 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3CC)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B15 compound treatment 271.6 84.4 0.44 272.3 87.9 0.46 0.6345 0.9998 1973850 ChemDiv1_007429 Cc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B16 compound treatment 271.7 84.5 0.44 268.3 83.9 0.44 0.6202 1.0 1323871 ChemDiv1_007430 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(OC)cc3OC)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B17 compound treatment 277.5 90.3 0.47 274.3 89.9 0.47 0.6636 1.0 1929035 ChemDiv1_007431 COc1cccc(c1)C2=NN(C(=O)c3cccc(Br)c3)C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B18 compound treatment 274.4 87.2 0.45 275.7 91.3 0.47 0.6573 0.9998 1611743 ChemDiv1_007432 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2CC(=O)NCCc5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B19 compound treatment 276.0 88.8 0.46 275.1 90.7 0.47 0.661 1.0 1973851 ChemDiv1_007433 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C(=C\c3ccccc3)/NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B20 compound treatment 272.2 85.0 0.44 275.9 91.5 0.48 0.6499 0.9994 1168744 ChemDiv1_007434 COc1ccccc1CNc2nc(nc3ccccc23)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B21 compound treatment 280.9 93.7 0.49 274.1 89.7 0.47 0.6754 0.9997 1973852 ChemDiv1_007435 COc1cc(Br)c(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B22 compound treatment 276.1 88.9 0.46 275.3 90.9 0.47 0.6621 1.0 1131374 ChemDiv1_007436 COc1ccc(cc1OC)c2nc(N3CCN(C)CC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B23 mock treatment 281.9 94.7 0.49 275.9 91.5 0.48 0.6857 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 B24 mock treatment 76.8 -110.0 -0.58 75.4 -109.0 -0.57 -0.8078 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C01 compound treatment 282.8 95.6 0.5 284.8 100.0 0.52 0.7217 0.9997 1973853 ChemDiv1_007437 CCOc1ccc(/C=C\2/SC(=S)N(CCC(=O)N3CCC(Cc4ccccc4)CC3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C02 compound treatment 282.1 94.9 0.5 285.4 101.0 0.53 0.7214 0.9996 1973854 ChemDiv1_007438 FC(F)(F)c1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C03 compound treatment 284.2 97.0 0.51 278.8 94.4 0.49 0.7049 0.9999 1973855 ChemDiv1_007439 O=C(CC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccccc3)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C04 compound treatment 281.7 94.5 0.49 276.9 92.5 0.48 0.6887 0.9999 1215589 ChemDiv1_007440 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4cccc(F)c4)c(OC)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C05 compound treatment 278.4 91.2 0.48 274.7 90.3 0.47 0.6684 1.0 1946354 ChemDiv1_007441 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3ccc4OCCOc4c3)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C06 compound treatment 276.8 89.6 0.47 279.9 95.5 0.5 0.6816 0.9995 1780066 ChemDiv1_007442 CCc1sc(cc1[N+](=O)[O-])c2c(C#N)c(N)nc3CCCCCCc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C07 compound treatment 282.1 94.9 0.5 274.2 89.8 0.47 0.6802 0.9996 1668262 ChemDiv1_007443 COc1cc(cc(OC)c1O)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C08 compound treatment 279.3 92.1 0.48 275.0 90.6 0.47 0.6728 1.0 1973856 ChemDiv1_007444 CN(C)CCCOC(=O)c1ccc2OCCOc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C09 compound treatment 280.7 93.5 0.49 278.5 94.1 0.49 0.6908 1.0 1973857 ChemDiv1_007445 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C10 compound treatment 276.0 88.8 0.46 277.1 92.7 0.48 0.6684 0.9998 1973858 ChemDiv1_007446 Cc1ccc2[nH]c(=O)c(cc2c1)C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C11 compound treatment 274.1 86.9 0.45 277.8 93.4 0.49 0.6639 0.9994 1973859 ChemDiv1_007447 CN1C(=O)C(CC(=O)C)(OC(=O)C)c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C12 compound treatment 277.2 90.0 0.47 272.6 88.2 0.46 0.6562 0.9999 1973860 ChemDiv1_007448 Fc1ccc(cc1)C(=O)N2N=C(CC2c3ccco3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C13 compound treatment 274.4 87.2 0.45 270.6 86.2 0.45 0.6386 1.0 1700808 ChemDiv1_007449 Cc1ccc2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C14 compound treatment 279.0 91.8 0.48 277.7 93.3 0.49 0.6816 1.0 1973861 ChemDiv1_007450 FC(F)(F)C(=O)NC(CC(=O)Nc1nnc(CCc2ccccc2)s1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C15 compound treatment 280.5 93.3 0.49 275.6 91.2 0.47 0.6794 0.9999 1973862 ChemDiv1_007451 COc1cccc(OCCOc2ccc(cc2OC)c3nc4sc5CCCCc5c4c(=O)[nH]3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C16 compound treatment 277.7 90.5 0.47 272.2 87.8 0.46 0.6566 0.9999 1083083 ChemDiv1_007452 OC1(C2CCCCCC2=O)C(=O)Nc3ccc(Br)cc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C17 compound treatment 281.0 93.8 0.49 273.8 89.4 0.46 0.6747 0.9997 1654302 ChemDiv1_007453 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C18 compound treatment 275.7 88.5 0.46 276.6 92.2 0.48 0.6654 0.9998 1973863 ChemDiv1_007454 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C19 compound treatment 278.3 91.1 0.48 272.5 88.1 0.46 0.6599 0.9998 1305788 ChemDiv1_007455 OC1(CC(=O)c2ccc3CCc4cccc2c43)C(=O)N(Cc5ccc(Cl)cc5)c6ccccc61 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C20 compound treatment 279.1 91.9 0.48 272.9 88.5 0.46 0.6644 0.9998 1934703 ChemDiv1_007456 CC1=NN(C(=O)c2cccc(Br)c2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C21 compound treatment 278.5 91.3 0.48 275.9 91.5 0.48 0.6732 1.0 1973864 ChemDiv1_007457 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C22 compound treatment 275.8 88.6 0.46 272.6 88.2 0.46 0.6511 1.0 1556482 ChemDiv1_007458 CC1=NN(C(=O)CCCc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C23 mock treatment 278.4 91.2 0.48 278.5 94.1 0.49 0.6824 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 C24 mock treatment 79.5 -108.0 -0.56 75.3 -109.0 -0.57 -0.7982 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D01 compound treatment 280.0 92.8 0.48 277.5 93.1 0.48 0.6846 1.0 1973865 ChemDiv1_007459 CCOC(=O)C1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D02 compound treatment 281.1 93.9 0.49 280.7 96.3 0.5 0.7004 0.9999 1527668 ChemDiv1_007460 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D03 compound treatment 279.3 92.1 0.48 276.3 91.9 0.48 0.6776 1.0 1929036 ChemDiv1_007461 OC1(CC(=NN1C(=O)CCc2ccccc2)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D04 compound treatment 280.3 93.1 0.49 274.1 89.7 0.47 0.6732 0.9998 1337823 ChemDiv1_007462 O=C(NCC1OCCc2ccccc12)C3COc4ccccc4O3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D05 compound treatment 285.6 98.4 0.51 276.9 92.5 0.48 0.703 0.9995 1928924 ChemDiv1_007463 CCCC1=NN(C(=O)Cc2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D06 compound treatment 290.5 103.0 0.54 288.8 104.0 0.54 0.7649 1.0 1973866 ChemDiv1_007464 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3ccccc3)C(=O)Nc4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D07 compound treatment 282.8 95.6 0.5 276.5 92.1 0.48 0.6912 0.9998 1928881 ChemDiv1_007465 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(Cl)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D08 compound treatment 277.4 90.2 0.47 275.9 91.5 0.48 0.6691 1.0 1973867 ChemDiv1_007466 CC1CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D09 compound treatment 276.5 89.3 0.47 278.2 93.8 0.49 0.6742 0.9997 1928400 ChemDiv1_007467 CC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D10 compound treatment 294.1 107.0 0.56 293.7 109.0 0.57 0.7961 1.0 1973868 ChemDiv1_007468 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccc(F)cc4F)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D11 compound treatment 281.2 94.0 0.49 275.6 91.2 0.47 0.682 0.9999 1393138 ChemDiv1_007469 CCC1=NN(C(=O)c2cccnc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D12 compound treatment 277.7 90.5 0.47 274.8 90.4 0.47 0.6662 1.0 1486493 ChemDiv1_007470 COc1ccc(NC(=O)Cn2c(nc3sc(C)c(C)c3c2=O)c4ccccc4Cl)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D13 compound treatment 275.4 88.2 0.46 273.8 89.4 0.46 0.654 1.0 1973869 ChemDiv1_007471 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(Br)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D14 compound treatment 271.2 84.0 0.44 273.6 89.2 0.46 0.6378 0.9996 1268546 ChemDiv1_007472 CCOC(=O)c1sc2nc(C)nc(NCc3ccccc3OC)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D15 compound treatment 274.9 87.7 0.46 272.2 87.8 0.46 0.6463 1.0 1929183 ChemDiv1_007473 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D16 compound treatment 271.3 84.1 0.44 269.1 84.7 0.44 0.6216 1.0 1613071 ChemDiv1_007474 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(F)c(Cl)c3)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D17 compound treatment 278.8 91.6 0.48 275.0 90.6 0.47 0.671 1.0 1928928 ChemDiv1_007475 COc1cccc(c1)C2=NN(C(=O)CCc3ccccc3)C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D18 compound treatment 273.5 86.3 0.45 272.0 87.6 0.46 0.6404 1.0 1973870 ChemDiv1_007476 Cc1sc2nc(c3ccccc3Cl)n(CC(=O)Nc4ccccc4C(F)(F)F)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D19 compound treatment 280.3 93.1 0.49 275.7 91.3 0.47 0.6791 0.9999 1951899 ChemDiv1_007477 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C(=C/c3ccco3)/NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D20 compound treatment 277.6 90.4 0.47 272.8 88.4 0.46 0.6585 0.9999 1696244 ChemDiv1_007478 CCC(C)Nc1nc(nc2ccccc12)c3cc(OC)c(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D21 compound treatment 278.5 91.3 0.48 273.5 89.1 0.46 0.6644 0.9999 1973871 ChemDiv1_007479 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)ccc1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D22 compound treatment 278.3 91.1 0.48 271.7 87.3 0.45 0.657 0.9997 1719783 ChemDiv1_007480 COc1ccc(cc1OC)c2nc(N3CCC(C)CC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D23 mock treatment 281.8 94.6 0.49 275.0 90.6 0.47 0.682 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 D24 mock treatment 79.1 -108.0 -0.56 79.4 -105.0 -0.55 -0.7846 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E01 compound treatment 286.4 99.2 0.52 280.1 95.7 0.5 0.7177 0.9998 1973872 ChemDiv1_007481 CCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cc(C)on3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E02 compound treatment 282.0 94.8 0.49 280.2 95.8 0.5 0.7019 1.0 1973873 ChemDiv1_007482 Clc1ccc2n(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E03 compound treatment 279.2 92.0 0.48 277.4 93.0 0.48 0.6813 1.0 1973874 ChemDiv1_007483 CCCCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E04 compound treatment 281.8 94.6 0.49 277.8 93.4 0.49 0.6923 1.0 1851246 ChemDiv1_007484 COc1cc(ccc1OCc2ccc(cc2)[N+](=O)[O-])C3C(=C(N)OC4=C3C(=O)CCC4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E05 compound treatment 278.4 91.2 0.48 273.4 89.0 0.46 0.6636 0.9999 1141167 ChemDiv1_007485 CCOC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E06 compound treatment 296.1 109.0 0.57 294.6 110.0 0.57 0.8068 1.0 1973875 ChemDiv1_007486 CCCC1=C(C(c2cc(OC)ccc2OC)n3c(=O)c(=Cc4ccc(o4)[N+](=O)[O-])sc3=N1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E07 compound treatment 282.8 95.6 0.5 279.4 95.0 0.49 0.7019 1.0 1973876 ChemDiv1_007487 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4ccc5OCOc5c4)C(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E08 compound treatment 276.6 89.4 0.47 273.7 89.3 0.46 0.6581 1.0 1180781 ChemDiv1_007488 CN(CCOC(=O)c1ccc2OCCOc2c1)Cc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E09 compound treatment 276.2 89.0 0.46 280.1 95.7 0.5 0.6801 0.9994 1973877 ChemDiv1_007489 CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E10 compound treatment 275.6 88.4 0.46 271.7 87.3 0.45 0.647 1.0 1598542 ChemDiv1_007490 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3ccccc3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E11 compound treatment 276.1 88.9 0.46 272.8 88.4 0.46 0.6529 1.0 1135758 ChemDiv1_007491 CC1=CC(C)(C)N(C(=O)CSc2nc3ccccc3o2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E12 compound treatment 275.0 87.8 0.46 272.1 87.7 0.46 0.6463 1.0 1783640 ChemDiv1_007492 OC(=O)CCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E13 compound treatment 273.0 85.8 0.45 268.4 84.0 0.44 0.6253 0.9999 1376685 ChemDiv1_007493 Cc1cc2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E14 compound treatment 280.1 92.9 0.48 269.8 85.4 0.44 0.6567 0.999 1950838 ChemDiv1_007494 O=C1C2C(C3C=CC2C4C3C(=O)N(Cc5cccnc5)C4=O)C(=O)N1Cc6cccnc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E15 compound treatment 279.1 91.9 0.48 274.8 90.4 0.47 0.6713 1.0 1973878 ChemDiv1_007495 CCOc1cc(ccc1OCCOc2cccc(OC)c2)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E16 compound treatment 276.6 89.4 0.47 274.0 89.6 0.47 0.6592 1.0 1704765 ChemDiv1_007496 OC1(CC(=O)c2cccs2)C(=O)Nc3ccc(Br)cc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E17 compound treatment 283.9 96.7 0.5 274.8 90.4 0.47 0.689 0.9994 1705505 ChemDiv1_007497 C(Oc1cccc(c1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E18 compound treatment 273.5 86.3 0.45 269.4 85.0 0.44 0.6308 1.0 1973879 ChemDiv1_007498 OC1(CC(=NN1C(=O)c2ccc(Br)cc2)c3ccccc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E19 compound treatment 280.2 93.0 0.49 275.5 91.1 0.47 0.678 0.9999 1211788 ChemDiv1_007499 CC(C(=O)c1ccccc1)C2(O)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E20 compound treatment 281.1 93.9 0.49 275.4 91.0 0.47 0.6809 0.9998 1973880 ChemDiv1_007500 CC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E21 compound treatment 275.8 88.6 0.46 275.7 91.3 0.47 0.6625 0.9999 1973881 ChemDiv1_007501 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E22 compound treatment 280.5 93.3 0.49 273.0 88.6 0.46 0.6699 0.9996 1973882 ChemDiv1_007502 CCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E23 mock treatment 279.7 92.5 0.48 275.3 90.9 0.47 0.6754 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 E24 mock treatment 81.1 -106.0 -0.55 81.5 -103.0 -0.53 -0.7695 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F01 compound treatment 291.6 104.0 0.54 287.4 103.0 0.54 0.7638 1.0 1137802 ChemDiv1_007503 COC(=O)C1=NN(C(=O)c2cccc(OC)c2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F02 compound treatment 282.7 95.5 0.5 277.6 93.2 0.48 0.6949 0.9999 1431491 ChemDiv1_007504 Clc1ccc(cc1)C(=O)CSc2ncnc3[nH]cnc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F03 compound treatment 279.5 92.3 0.48 279.4 95.0 0.49 0.6897 0.9999 1973883 ChemDiv1_007505 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccncc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F04 compound treatment 280.9 93.7 0.49 278.6 94.2 0.49 0.6919 1.0 1385162 ChemDiv1_007506 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cc(ccc2Cl)c3nc4ccc(C)cc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F05 compound treatment 278.3 91.1 0.48 278.3 93.9 0.49 0.6813 0.9999 1973884 ChemDiv1_007507 CC(C)(C)C1(O)CC(=NN1C(=O)Cc2ccc(cc2)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F06 compound treatment 223.7 36.5 0.19 213.0 28.6 0.15 0.2398 0.9925 1973885 ChemDiv1_007508 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)Nc4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F07 compound treatment 284.1 96.9 0.51 272.5 88.1 0.46 0.6813 0.9988 1928940 ChemDiv1_007509 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)c3ccc(Cl)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F08 compound treatment 283.9 96.7 0.5 281.3 96.9 0.5 0.7129 1.0 1973886 ChemDiv1_007510 Clc1ccc(Oc2ccc(NC(=O)Cn3c4ccccc4c(=O)c5ccc(Cl)cc35)cc2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F09 compound treatment 279.0 91.8 0.48 274.2 89.8 0.47 0.6688 0.9999 1166343 ChemDiv1_007511 CCC1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F10 compound treatment 278.5 91.3 0.48 276.8 92.4 0.48 0.6765 1.0 1973887 ChemDiv1_007512 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc(Oc5ccc(F)cc5F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F11 compound treatment 290.3 103.0 0.54 284.0 99.6 0.52 0.7465 0.9998 1532841 ChemDiv1_007513 CCC1=NN(C(=O)c2ccncc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F12 compound treatment 279.5 92.3 0.48 274.8 90.4 0.47 0.6728 0.9999 1338234 ChemDiv1_007514 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccccc3Cl)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F13 compound treatment 276.6 89.4 0.47 275.6 91.2 0.47 0.6651 1.0 1973888 ChemDiv1_007515 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F14 compound treatment 279.0 91.8 0.48 277.6 93.2 0.48 0.6813 1.0 1479828 ChemDiv1_007516 CCOC(=O)c1sc2nc(C)nc(N(C)C3CCCCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F15 compound treatment 271.1 83.9 0.44 274.2 89.8 0.47 0.6396 0.9995 1929087 ChemDiv1_007517 OC1(CC(=NN1C(=O)Cc2ccccc2)c3cccc(Br)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F16 compound treatment 276.3 89.1 0.46 273.8 89.4 0.46 0.6573 1.0 1344354 ChemDiv1_007518 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F17 compound treatment 284.7 97.5 0.51 277.5 93.1 0.48 0.7019 0.9997 1948811 ChemDiv1_007519 COc1cccc(c1)C2=NN(C(=O)c3ccc(cc3)C(C)(C)C)C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F18 compound treatment 280.1 92.9 0.48 277.2 92.8 0.48 0.6839 1.0 1973889 ChemDiv1_007520 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2CC(=O)Nc5ccccc5C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F19 compound treatment 278.4 91.2 0.48 274.2 89.8 0.47 0.6666 1.0 1973890 ChemDiv1_007521 Cc1ncc([N+](=O)[O-])n1CCSc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F20 compound treatment 278.0 90.8 0.47 273.9 89.5 0.47 0.664 1.0 1319714 ChemDiv1_007522 COc1cc(cc(OC)c1OC)c2nc(N3CCC(C)CC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F21 compound treatment 276.4 89.2 0.47 271.8 87.4 0.45 0.6504 0.9999 1973891 ChemDiv1_007523 CCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F22 compound treatment 275.7 88.5 0.46 278.1 93.7 0.49 0.6709 0.9996 1973892 ChemDiv1_007524 COc1cc(cc(OC)c1OC)c2nc(Nc3cccc(c3)[N+](=O)[O-])c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F23 mock treatment 277.4 90.2 0.47 275.3 90.9 0.47 0.6669 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 F24 mock treatment 76.6 -111.0 -0.58 76.2 -108.0 -0.56 -0.8056 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G01 compound treatment 282.0 94.8 0.49 284.3 99.9 0.52 0.717 0.9997 1973893 ChemDiv1_007525 CCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)NC3=NCCS3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G02 compound treatment 287.7 101.0 0.52 282.1 97.7 0.51 0.7299 0.9999 1973894 ChemDiv1_007526 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)Cn3c4ccccc4c(=O)c5cc(Cl)ccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G03 compound treatment 288.7 102.0 0.53 280.2 95.8 0.5 0.7266 0.9995 1973895 ChemDiv1_007527 CCCCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G04 compound treatment 275.8 88.6 0.46 276.4 92.0 0.48 0.6651 0.9999 1851266 ChemDiv1_007528 COC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4ccc(cc4)[N+](=O)[O-])c(OC)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G05 compound treatment 280.6 93.4 0.49 274.9 90.5 0.47 0.6772 0.9998 1179146 ChemDiv1_007529 COC(=O)COC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G06 compound treatment 274.6 87.4 0.46 272.8 88.4 0.46 0.6474 1.0 1691466 ChemDiv1_007530 COc1ccc2c3CCN(CCC(=O)NN)C(C)c3[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G07 compound treatment 277.1 89.9 0.47 279.5 95.1 0.49 0.6812 0.9997 1973896 ChemDiv1_007531 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4cc5OCOc5cc4[N+](=O)[O-])C(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G08 compound treatment 280.2 93.0 0.49 279.4 95.0 0.49 0.6923 1.0 1300480 ChemDiv1_007532 O=C(Oc1cc(=O)oc2ccccc12)c3ccc4OCCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G09 compound treatment 280.5 93.3 0.49 274.7 90.3 0.47 0.6761 0.9998 1973897 ChemDiv1_007533 CC1(C)Cc2c(CO1)sc3nc(SCC=C)n(Cc4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G10 compound treatment 277.3 90.1 0.47 273.5 89.1 0.46 0.6599 1.0 1256212 ChemDiv1_007534 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G11 compound treatment 278.8 91.6 0.48 277.3 92.9 0.48 0.6794 1.0 1419221 ChemDiv1_007535 CC1(C)N(C(=O)CSc2nc3ccccc3o2)c4ccccc4-c5c1ssc5=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G12 compound treatment 275.7 88.5 0.46 275.0 90.6 0.47 0.6595 0.9999 1973898 ChemDiv1_007536 OC(=O)CCC(=O)N1N=C(CC1c2ccc(F)cc2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G13 compound treatment 276.3 89.1 0.46 270.7 86.3 0.45 0.6459 0.9998 1680965 ChemDiv1_007537 CCOc1ccc2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G14 compound treatment 276.7 89.5 0.47 274.8 90.4 0.47 0.6625 1.0 1941625 ChemDiv1_007538 Fc1ccc(CN2C(=O)C3C(C4C=CC3C5C4C(=O)N(Cc6ccc(F)cc6)C5=O)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G15 compound treatment 277.4 90.2 0.47 277.1 92.7 0.48 0.6735 0.9999 1973899 ChemDiv1_007539 COc1ccccc1OCCOc2ccc(cc2c3nc4sc5CCCCc5c4c(=O)[nH]3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G16 compound treatment 280.6 93.4 0.49 276.8 92.4 0.48 0.6842 1.0 1341286 ChemDiv1_007540 OC1(CC(=O)c2ccco2)C(=O)Nc3ccccc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G17 compound treatment 279.5 92.3 0.48 275.5 91.1 0.47 0.6754 1.0 1493770 ChemDiv1_007541 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G18 compound treatment 291.8 105.0 0.55 288.5 104.0 0.54 0.7685 1.0 1973900 ChemDiv1_007542 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3ccccc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G19 compound treatment 276.8 89.6 0.47 276.4 92.0 0.48 0.6687 0.9999 1366573 ChemDiv1_007543 COc1ccc(C(=O)CC2(O)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc42)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G20 compound treatment 273.3 86.1 0.45 275.7 91.3 0.47 0.6533 0.9996 1951330 ChemDiv1_007544 CC1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G21 compound treatment 277.4 90.2 0.47 274.7 90.3 0.47 0.6647 1.0 1973901 ChemDiv1_007545 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc4CCCc4c3)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G22 compound treatment 272.7 85.5 0.45 271.0 86.6 0.45 0.6338 1.0 1951729 ChemDiv1_007546 CCOC(=O)C1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G23 mock treatment 279.2 92.0 0.48 278.1 93.7 0.49 0.6838 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 G24 mock treatment 79.0 -108.0 -0.56 75.0 -109.0 -0.57 -0.8011 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H01 compound treatment 285.9 98.7 0.51 286.4 102.0 0.53 0.7391 0.9999 1703408 ChemDiv1_007547 COC(=O)C1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H02 compound treatment 281.4 94.2 0.49 281.8 97.4 0.51 0.7056 0.9999 1546110 ChemDiv1_007548 CC1(C)CC(=O)C(Sc2ncnc3[nH]cnc23)C(=O)C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H03 compound treatment 279.3 92.1 0.48 275.5 91.1 0.47 0.6747 1.0 1973902 ChemDiv1_007549 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccncc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H04 compound treatment 283.2 96.0 0.5 274.2 89.8 0.47 0.6843 0.9994 1175782 ChemDiv1_007550 CC1=C(C(NC(=O)N1)c2cccc(Br)c2)C(=O)OCc3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H05 compound treatment 275.6 88.4 0.46 274.5 90.1 0.47 0.6573 1.0 1928903 ChemDiv1_007551 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H06 compound treatment 276.9 89.7 0.47 279.5 95.1 0.49 0.6805 0.9996 1443813 ChemDiv1_007552 Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H07 compound treatment 277.8 90.6 0.47 276.1 91.7 0.48 0.6713 1.0 1928999 ChemDiv1_007553 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(Cl)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H08 compound treatment 279.2 92.0 0.48 280.6 96.2 0.5 0.693 0.9998 1599610 ChemDiv1_007554 COc1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4F)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H09 compound treatment 288.0 101.0 0.53 285.7 101.0 0.53 0.7442 1.0 1208313 ChemDiv1_007555 CCC1=NN(C(=O)c2cccc(C)c2O)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H10 compound treatment 279.3 92.1 0.48 274.0 89.6 0.47 0.6691 0.9999 1664726 ChemDiv1_007556 COc1ccc(Cc2nc3cc(C)c(C)cc3n(C)c2=O)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H11 compound treatment 288.9 102.0 0.53 288.3 104.0 0.54 0.7571 1.0 1973903 ChemDiv1_007557 Cc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H12 compound treatment 277.7 90.5 0.47 277.4 93.0 0.48 0.6757 0.9999 1358536 ChemDiv1_007558 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccc(C)cc3)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H13 compound treatment 277.2 90.0 0.47 274.9 90.5 0.47 0.6647 1.0 1973904 ChemDiv1_007559 OC1(CC(=NN1C(=O)c2ccccc2)c3ccc(F)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H14 compound treatment 277.7 90.5 0.47 268.8 84.4 0.44 0.6441 0.9993 1414412 ChemDiv1_007560 CCOC(=O)c1nc(N2CCN(CC2)c3ccccc3)c4ccccc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H15 compound treatment 277.4 90.2 0.47 279.2 94.8 0.49 0.6812 0.9997 1928917 ChemDiv1_007561 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(Br)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H16 compound treatment 275.3 88.1 0.46 270.9 86.5 0.45 0.643 0.9999 1335128 ChemDiv1_007562 CCN(CC)C(=O)COc1nc(Cc2ccccc2)nc3sc4CCCCc4c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H17 compound treatment 283.8 96.6 0.5 282.0 97.6 0.51 0.7151 1.0 1973905 ChemDiv1_007563 COc1cccc(c1)C2=NN(C(=O)c3ccc(Cl)cc3)C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H18 compound treatment 276.7 89.5 0.47 274.5 90.1 0.47 0.6614 1.0 1670131 ChemDiv1_007564 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2CC(=O)Nc5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H19 compound treatment 275.6 88.4 0.46 273.6 89.2 0.46 0.654 1.0 1389391 ChemDiv1_007565 Cn1c(=O)n(C)c2nc(SCC(=O)Nc3ccc4OCOc4c3)n(Cc5ccccc5)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H20 compound treatment 273.6 86.4 0.45 274.1 89.7 0.47 0.6485 0.9999 1617405 ChemDiv1_007566 CCOC(=O)c1sc2nc(C)nc(NCCC3=CCCCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H21 compound treatment 278.9 91.7 0.48 276.9 92.5 0.48 0.6783 1.0 1973906 ChemDiv1_007567 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)ccc1OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H22 compound treatment 274.9 87.7 0.46 273.5 89.1 0.46 0.6511 1.0 1687239 ChemDiv1_007568 COc1cc(cc(OC)c1OC)c2nc(NC3CCCCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H23 mock treatment 281.1 93.9 0.49 276.5 92.1 0.48 0.685 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 H24 mock treatment 76.2 -111.0 -0.58 69.1 -115.0 -0.6 -0.8332 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I01 compound treatment 286.3 99.1 0.52 282.1 97.7 0.51 0.7247 1.0 1973907 ChemDiv1_007569 CCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(O)c(c3)C(=O)O)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I02 compound treatment 286.0 98.8 0.52 284.2 99.8 0.52 0.7313 1.0 1973908 ChemDiv1_007570 Cc1ccc(F)cc1NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I03 compound treatment 281.2 94.0 0.49 280.4 96.0 0.5 0.6997 1.0 1973909 ChemDiv1_007571 CC/N=C/1\SC(CC(=O)Nc2ccc(cc2)C(F)(F)F)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I04 compound treatment 282.3 95.1 0.5 278.6 94.2 0.49 0.6971 1.0 1392460 ChemDiv1_007572 COC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4ccc(Cl)cc4)c(OC)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I05 compound treatment 278.8 91.6 0.48 277.6 93.2 0.48 0.6805 1.0 1187995 ChemDiv1_007573 COC(=O)C(C)OC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I06 compound treatment 280.0 92.8 0.48 278.8 94.4 0.49 0.6894 1.0 1973910 ChemDiv1_007574 ClC1=CCC2C(C1)C(=O)N(CN3CCN(CN4C(=O)C5CC=C(Cl)CC5C4=O)CC3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I07 compound treatment 281.1 93.9 0.49 280.6 96.2 0.5 0.7 0.9999 1523222 ChemDiv1_007575 COc1cc(ccc1O)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I08 compound treatment 282.3 95.1 0.5 277.0 92.6 0.48 0.6912 0.9999 1557475 ChemDiv1_007576 O=C(Nc1ccccn1)c2ccc3OCCOc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I09 compound treatment 272.3 85.1 0.44 279.1 94.7 0.49 0.6621 0.9987 1932962 ChemDiv1_007577 CC(=C)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC(=C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I10 compound treatment 276.1 88.9 0.46 274.6 90.2 0.47 0.6595 1.0 1155139 ChemDiv1_007578 COc1ccc(cc1)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I11 compound treatment 278.8 91.6 0.48 277.2 92.8 0.48 0.6791 1.0 1546150 ChemDiv1_007579 Cc1ccc2N(C(=O)CSc3nc4ccccc4o3)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I12 compound treatment 274.9 87.7 0.46 274.0 89.6 0.47 0.6529 1.0 1973911 ChemDiv1_007580 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I13 compound treatment 277.5 90.3 0.47 275.2 90.8 0.47 0.6669 1.0 1417836 ChemDiv1_007581 Cn1cnnc1SCC(=O)N2c3ccccc3CCc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I14 compound treatment 280.4 93.2 0.49 275.2 90.8 0.47 0.6776 0.9999 1587367 ChemDiv1_007582 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(OC3(C)C=C4)C5OCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I15 compound treatment 279.5 92.3 0.48 271.0 86.6 0.45 0.6588 0.9994 1973912 ChemDiv1_007583 COc1cc(ccc1OCCOCCOc2ccccc2C)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I16 compound treatment 278.4 91.2 0.48 276.2 91.8 0.48 0.6739 1.0 1493008 ChemDiv1_007584 Cc1cc(ccc1Cl)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I17 compound treatment 276.2 89.0 0.46 271.8 87.4 0.45 0.6496 0.9999 1973913 ChemDiv1_007585 CCC([N+](=O)[O-])C1(O)C(=O)Nc2ccccc21 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I18 compound treatment 285.7 98.5 0.51 281.2 96.8 0.5 0.7192 0.9999 1973914 ChemDiv1_007586 CC(C)(C)c1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I19 compound treatment 281.3 94.1 0.49 278.3 93.9 0.49 0.6923 1.0 1204438 ChemDiv1_007587 CCCOc1ccc(cc1)C(=O)Nc2cccc(c3nc4ccccc4[nH]3)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I20 compound treatment 274.0 86.8 0.45 275.9 91.5 0.48 0.6566 0.9997 1625724 ChemDiv1_007588 CC1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I21 compound treatment 276.9 89.7 0.47 278.4 94.0 0.49 0.6765 0.9998 1973915 ChemDiv1_007589 OC(=O)c1ccc2[nH]c(=O)c(Cc3ccc(OC(F)F)cc3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I22 compound treatment 277.4 90.2 0.47 274.2 89.8 0.47 0.6629 1.0 1941159 ChemDiv1_007590 CCOC(=O)C1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I23 mock treatment 273.7 86.5 0.45 275.8 91.4 0.48 0.6551 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 I24 mock treatment 73.3 -114.0 -0.59 75.4 -109.0 -0.57 -0.8207 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J01 compound treatment 281.9 94.7 0.49 279.7 95.3 0.5 0.6997 1.0 1951261 ChemDiv1_007591 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J02 compound treatment 280.6 93.4 0.49 279.9 95.5 0.5 0.6956 1.0 1514625 ChemDiv1_007592 Cn1c(N)c(C(=O)CSc2ncnc3[nH]cnc23)c(=O)n(C)c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J03 compound treatment 282.1 94.9 0.5 279.8 95.4 0.5 0.7008 1.0 1973916 ChemDiv1_007593 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccncc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J04 compound treatment 281.9 94.7 0.49 276.0 91.6 0.48 0.6861 0.9998 1973917 ChemDiv1_007594 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J05 compound treatment 280.0 92.8 0.48 274.2 89.8 0.47 0.6725 0.9998 1951412 ChemDiv1_007595 OC1(CC(=NN1C(=O)c2ccccc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J06 compound treatment 279.2 92.0 0.48 280.9 96.5 0.5 0.6941 0.9998 1973918 ChemDiv1_007596 CC/1=NN(C(=O)\C1=C/Nc2c(C)[nH]n(c3ccccc3)c2=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J07 compound treatment 280.6 93.4 0.49 280.6 96.2 0.5 0.6982 0.9999 1931115 ChemDiv1_007597 Cc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J08 compound treatment 279.9 92.7 0.48 277.3 92.9 0.48 0.6835 1.0 1669784 ChemDiv1_007598 Fc1ccc(cc1)N2CCN(CC2)C(=O)Cn3c(nc4ccccc4c3=O)c5ccccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J09 compound treatment 278.7 91.5 0.48 273.4 89.0 0.46 0.6647 0.9999 1476117 ChemDiv1_007599 CCC1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J10 compound treatment 276.0 88.8 0.46 277.5 93.1 0.48 0.6698 0.9998 1973919 ChemDiv1_007600 Cc1cc2nc(Cc3ccc(OC(F)F)cc3)c(=O)n(C)c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J11 compound treatment 285.3 98.1 0.51 279.6 95.2 0.49 0.7119 0.9999 1973920 ChemDiv1_007601 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)c3ccc(Br)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J12 compound treatment 274.7 87.5 0.46 272.3 87.9 0.46 0.6459 1.0 1315135 ChemDiv1_007602 CCOC(=O)c1sc2nc(C)nc(N3CCCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J13 compound treatment 276.1 88.9 0.46 272.9 88.5 0.46 0.6533 1.0 1948828 ChemDiv1_007603 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J14 compound treatment 279.3 92.1 0.48 272.6 88.2 0.46 0.664 0.9997 1973921 ChemDiv1_007604 FC(F)(F)c1cccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J15 compound treatment 276.8 89.6 0.47 272.5 88.1 0.46 0.6544 0.9999 1973922 ChemDiv1_007605 COc1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J16 compound treatment 280.4 93.2 0.49 273.6 89.2 0.46 0.6717 0.9997 1973923 ChemDiv1_007606 O=C(Cn1c(Cc2ccccc2)nc3sc4CCCCc4c3c1=O)Nc5ccc(Oc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J17 compound treatment 275.3 88.1 0.46 275.8 91.4 0.48 0.661 0.9999 1289604 ChemDiv1_007607 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4[nH]3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J18 compound treatment 275.9 88.7 0.46 276.3 91.9 0.48 0.6651 0.9999 1656327 ChemDiv1_007608 COc1ccc(CCNC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J19 compound treatment 279.5 92.3 0.48 274.1 89.7 0.47 0.6702 0.9999 1973924 ChemDiv1_007609 CCC(=O)n1cc(/C=C/2\S/C(=N\C)/N(C)C2=O)c(n1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J20 compound treatment 282.5 95.3 0.5 273.8 89.4 0.46 0.6802 0.9994 1706081 ChemDiv1_007610 CCOC(=O)c1sc2nc(C)nc(NCc3ccc4OCOc4c3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J21 compound treatment 277.9 90.7 0.47 272.3 87.9 0.46 0.6577 0.9998 1973925 ChemDiv1_007611 CCCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J22 compound treatment 278.9 91.7 0.48 275.6 91.2 0.47 0.6735 1.0 1276303 ChemDiv1_007612 COc1cc(cc(OC)c1OC)c2nc(NCc3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J23 mock treatment 283.2 96.0 0.5 277.7 93.3 0.49 0.6971 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 J24 mock treatment 84.5 -103.0 -0.54 78.6 -106.0 -0.55 -0.7676 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K01 compound treatment 290.1 103.0 0.54 289.5 105.0 0.55 0.7659 1.0 1973926 ChemDiv1_007613 NS(=O)(=O)c1ccc(NC(=O)CCCN2C(=O)S/C(=C/C=C/c3ccccc3)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K02 compound treatment 284.4 97.2 0.51 280.9 96.5 0.5 0.7133 1.0 1973927 ChemDiv1_007614 Clc1ccc2n(CC(=O)N3CCN(CC3)c4ccccc4)c5ccccc5c(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K03 compound treatment 285.0 97.8 0.51 279.0 94.6 0.49 0.7085 0.9998 1973928 ChemDiv1_007615 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K04 compound treatment 279.9 92.7 0.48 270.3 85.9 0.45 0.6578 0.9992 1973929 ChemDiv1_007616 COC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K05 compound treatment 278.9 91.7 0.48 275.6 91.2 0.47 0.6735 1.0 1163202 ChemDiv1_007617 COC(=O)c1ccc(Oc2nc(SC)nc(n2)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K06 compound treatment 277.6 90.4 0.47 274.2 89.8 0.47 0.6636 1.0 1973930 ChemDiv1_007618 CC(CN1C(=O)C2C(C3C2C4C=CC3C5C4C(=O)N(CC(C)c6ccccc6)C5=O)C1=O)c7ccccc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K07 compound treatment 280.7 93.5 0.49 275.6 91.2 0.47 0.6802 0.9999 1269746 ChemDiv1_007619 CCOc1cc(ccc1O)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K08 compound treatment 279.7 92.5 0.48 271.5 87.1 0.45 0.6614 0.9995 1599859 ChemDiv1_007620 COc1cccc(C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K09 compound treatment 284.9 97.7 0.51 280.5 96.1 0.5 0.7137 1.0 1515055 ChemDiv1_007621 CCOC(=O)CSc1nc2sc3CN(C)CCc3c2c(=O)n1Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K10 compound treatment 278.7 91.5 0.48 275.1 90.7 0.47 0.671 1.0 1973931 ChemDiv1_007622 COc1ccc(cc1OC)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K11 compound treatment 280.0 92.8 0.48 279.1 94.7 0.49 0.6905 1.0 1707885 ChemDiv1_007623 O=C(CSc1nc2ccccc2o1)n3c4ccccc4c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K12 compound treatment 278.5 91.3 0.48 270.6 86.2 0.45 0.6537 0.9995 1296739 ChemDiv1_007624 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K13 compound treatment 280.4 93.2 0.49 274.7 90.3 0.47 0.6758 0.9998 1669756 ChemDiv1_007625 COc1ccc2N(C(=O)CSc3nnc(C)s3)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K14 compound treatment 278.7 91.5 0.48 279.3 94.9 0.49 0.6864 0.9999 1697207 ChemDiv1_007626 O=C1N(CN2CCCCC2)c3ccccc3C41OCCCO4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K15 compound treatment 277.0 89.8 0.47 275.1 90.7 0.47 0.6647 1.0 1973932 ChemDiv1_007627 COc1cccc(OCCOc2c(Cl)cc(cc2OC)c3nc4sc5CCCCc5c4c(=O)[nH]3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K16 compound treatment 277.8 90.6 0.47 276.1 91.7 0.48 0.6713 1.0 1476098 ChemDiv1_007628 Cc1ccc(cc1C)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K17 compound treatment 276.3 89.1 0.46 275.8 91.4 0.48 0.6647 0.9999 1303983 ChemDiv1_007629 OC1(CC(=O)c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K18 compound treatment 277.9 90.7 0.47 273.6 89.2 0.46 0.6625 0.9999 1973933 ChemDiv1_007630 OC1(CC(=NN1C(=O)CCCc2ccccc2)c3ccccc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K19 compound treatment 278.8 91.6 0.48 273.4 89.0 0.46 0.6651 0.9999 1973934 ChemDiv1_007631 Cc1c(NC(=O)c2cccc([N+](=O)[O-])c2C)cccc1c3nc4ccccc4[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K20 compound treatment 278.2 91.0 0.47 283.2 98.8 0.51 0.6989 0.9992 1517705 ChemDiv1_007632 CC1=NN(C(=O)c2cccc(O)c2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K21 compound treatment 279.0 91.8 0.48 276.7 92.3 0.48 0.678 1.0 1973935 ChemDiv1_007633 Clc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccc(Cl)cc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K22 compound treatment 276.0 88.8 0.46 274.6 90.2 0.47 0.6592 1.0 1973936 ChemDiv1_007634 CCOC(=O)C1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K23 mock treatment 276.6 89.4 0.47 278.8 94.4 0.49 0.6768 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 K24 mock treatment 75.8 -111.0 -0.58 79.2 -105.0 -0.55 -0.7975 -0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L01 compound treatment 283.8 96.6 0.5 280.1 95.7 0.5 0.7082 1.0 1973937 ChemDiv1_007635 OC1(CC(=NN1C(=O)Cc2ccc(cc2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L02 compound treatment 285.7 98.5 0.51 279.1 94.7 0.49 0.7115 0.9998 1427755 ChemDiv1_007636 C(N1CCCCC1)n2c3ccccc3c4nc5ccccc5nc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L03 compound treatment 277.6 90.4 0.47 280.4 96.0 0.5 0.6864 0.9996 1951195 ChemDiv1_007637 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L04 compound treatment 280.1 92.9 0.48 274.5 90.1 0.47 0.6739 0.9999 1423415 ChemDiv1_007638 CCC(=O)Nc1nc2CC(C)(C)CC(=O)c2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L05 compound treatment 278.8 91.6 0.48 277.5 93.1 0.48 0.6802 1.0 1929125 ChemDiv1_007639 CC(C)(C)c1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L06 compound treatment 279.9 92.7 0.48 276.5 92.1 0.48 0.6805 1.0 1021801 ChemDiv1_007640 CSc1nc(N)nc2[nH]cnc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L07 compound treatment 275.6 88.4 0.46 272.5 88.1 0.46 0.65 1.0 1948700 ChemDiv1_007641 OC1(CC(=NN1C(=O)CCc2ccccc2)c3ccc(Cl)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L08 compound treatment 288.9 102.0 0.53 285.8 101.0 0.53 0.7479 1.0 1973938 ChemDiv1_007642 CCOC(=O)N1CCC(CC1)NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L09 compound treatment 275.9 88.7 0.46 272.9 88.5 0.46 0.6526 1.0 1779844 ChemDiv1_007643 CCC1=NN(C(=O)Cc2ccc(cc2)[N+](=O)[O-])C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L10 compound treatment 277.4 90.2 0.47 277.7 93.3 0.49 0.6757 0.9999 1973939 ChemDiv1_007644 Cc1sc2nc(c3ccccc3Cl)n(CC(=O)Nc4ccc(C)c(Cl)c4)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L11 compound treatment 275.5 88.3 0.46 277.2 92.8 0.48 0.6669 0.9997 1929049 ChemDiv1_007645 OC1(CC(=NN1C(=O)Cc2ccc(cc2)[N+](=O)[O-])c3ccc(Br)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L12 compound treatment 281.5 94.3 0.49 276.7 92.3 0.48 0.6872 0.9999 1973940 ChemDiv1_007646 CCOC(=O)c1sc(NC(=O)Cn2cnc3ccccc3c2=O)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L13 compound treatment 278.3 91.1 0.48 275.3 90.9 0.47 0.6702 1.0 1973941 ChemDiv1_007647 OC1(CC(=NN1C(=O)c2ccncc2)c3ccc(F)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L14 compound treatment 279.2 92.0 0.48 277.4 93.0 0.48 0.6813 1.0 1575867 ChemDiv1_007648 Cc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L15 compound treatment 258.5 71.3 0.37 277.2 92.8 0.48 0.6042 0.9917 1929068 ChemDiv1_007649 COc1cccc(c1)C2=NN(C(=O)Cc3ccccc3)C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L16 compound treatment 279.2 92.0 0.48 280.1 95.7 0.5 0.6912 0.9998 1351746 ChemDiv1_007650 COc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L17 compound treatment 273.5 86.3 0.45 276.3 91.9 0.48 0.6562 0.9996 1183225 ChemDiv1_007651 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(C)cc(C)n3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L18 compound treatment 277.5 90.3 0.47 276.0 91.6 0.48 0.6699 1.0 1547864 ChemDiv1_007652 Brc1cccc(Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L19 compound treatment 274.6 87.4 0.46 274.9 90.5 0.47 0.6551 0.9999 1177977 ChemDiv1_007653 CCC(=O)Nc1nc2[nH]c(cc(=O)n2n1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L20 compound treatment 282.0 94.8 0.49 274.0 89.6 0.47 0.6791 0.9996 1288085 ChemDiv1_007654 CCOC(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L21 compound treatment 277.9 90.7 0.47 272.9 88.5 0.46 0.6599 0.9999 1232212 ChemDiv1_007655 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L22 compound treatment 276.7 89.5 0.47 275.7 91.3 0.47 0.6658 1.0 1739639 ChemDiv1_007656 COC(=O)c1cc(Nc2nc(nc3ccccc23)c4cc(OC)c(OC)c(OC)c4)cc(c1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L23 mock treatment 279.1 91.9 0.48 278.2 93.8 0.49 0.6838 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 L24 mock treatment 79.5 -108.0 -0.56 79.7 -105.0 -0.54 -0.782 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M01 compound treatment 285.3 98.1 0.51 284.0 99.6 0.52 0.728 1.0 1973942 ChemDiv1_007657 CCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M02 compound treatment 281.0 93.8 0.49 282.9 98.5 0.51 0.7081 0.9997 1973943 ChemDiv1_007658 Fc1ccc(CNC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M03 compound treatment 345.7 159.0 0.83 341.0 157.0 0.81 1.1603 1.0 1973944 ChemDiv1_007659 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)cc(CC=C)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M04 compound treatment 278.2 91.0 0.47 279.3 94.9 0.49 0.6846 0.9998 1973945 ChemDiv1_007660 CCOc1ccccc1C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M05 compound treatment 280.1 92.9 0.48 273.8 89.4 0.46 0.6714 0.9998 1240730 ChemDiv1_007661 COC(=O)COC(=O)c1ccc(Oc2nc(OC)nc(n2)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M06 compound treatment 281.5 94.3 0.49 278.6 94.2 0.49 0.6942 1.0 1703966 ChemDiv1_007662 O=C(N1CCOCC1)c2ccc3OCCOc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M07 compound treatment 281.2 94.0 0.49 277.7 93.3 0.49 0.6897 1.0 1973946 ChemDiv1_007663 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M08 compound treatment 284.7 97.5 0.51 282.8 98.4 0.51 0.7214 1.0 1532753 ChemDiv1_007664 COc1ccc(cc1)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M09 compound treatment 276.6 89.4 0.47 275.9 91.5 0.48 0.6662 1.0 1973947 ChemDiv1_007665 CCC1(C)Cc2c(CO1)sc3nc(SCC(=O)OC)n(Cc4ccccc4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M10 compound treatment 285.3 98.1 0.51 282.5 98.1 0.51 0.7225 1.0 1973948 ChemDiv1_007666 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M11 compound treatment 272.2 85.0 0.44 273.5 89.1 0.46 0.6411 0.9998 1307335 ChemDiv1_007667 CCOc1ccc2N(C(=O)CSc3nnc[nH]3)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M12 compound treatment 276.2 89.0 0.46 275.7 91.3 0.47 0.664 0.9999 1156043 ChemDiv1_007668 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCCC(=O)O)c4cccs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M13 compound treatment 275.4 88.2 0.46 276.6 92.2 0.48 0.6643 0.9998 1329688 ChemDiv1_007669 CCOc1ccc2N(C(=O)CSc3nnc(C)s3)C(C)(C)c4ssc(=S)c4-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M14 compound treatment 279.4 92.2 0.48 273.9 89.5 0.47 0.6691 0.9999 1293822 ChemDiv1_007670 OC1(C2CCCC(C2=O)C3(O)C(=O)Nc4ccccc43)C(=O)Nc5ccccc51 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M15 compound treatment 266.3 79.1 0.41 274.3 89.9 0.47 0.6223 0.9981 1973949 ChemDiv1_007671 COc1cc(ccc1OCCOCCOc2ccc(C)c(C)c2)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M16 compound treatment 278.0 90.8 0.47 274.0 89.6 0.47 0.6643 1.0 1973950 ChemDiv1_007672 CCC1=NN(C(=O)c2cccc(Br)c2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M17 compound treatment 279.8 92.6 0.48 275.3 90.9 0.47 0.6758 0.9999 1304737 ChemDiv1_007673 OC1(CC(=O)c2ccc3CCCCc3c2)C(=O)Nc4ccc(Br)cc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M18 compound treatment 278.6 91.4 0.48 273.5 89.1 0.46 0.6647 0.9999 1973951 ChemDiv1_007674 CCCCC1=NN(C(=O)COc2ccccc2C)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M19 compound treatment 279.7 92.5 0.48 275.4 91.0 0.47 0.6758 1.0 1973952 ChemDiv1_007675 Cn1c(SCc2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])nc5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M20 compound treatment 279.1 91.9 0.48 280.4 96.0 0.5 0.6919 0.9998 1683145 ChemDiv1_007676 COc1ccc(cc1)C(=O)N2N=C(C)CC2(O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M21 compound treatment 275.7 88.5 0.46 276.0 91.6 0.48 0.6632 0.9999 1503056 ChemDiv1_007677 CCOC(=O)c1nc(Nc2ccc(OC)cc2Cl)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M22 compound treatment 279.0 91.8 0.48 277.1 92.7 0.48 0.6794 1.0 1701386 ChemDiv1_007678 CCOC(=O)C1=NN(C(=O)COc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M23 mock treatment 280.1 92.9 0.48 278.5 94.1 0.49 0.6886 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 M24 mock treatment 196.1 8.91 0.05 185.0 0.616 0.0 0.0351 0.754 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N01 compound treatment 283.7 96.5 0.5 282.3 97.9 0.51 0.7159 1.0 1929030 ChemDiv1_007679 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N02 compound treatment 280.7 93.5 0.49 280.8 96.4 0.5 0.6993 0.9999 1593944 ChemDiv1_007680 C(N1CCOCC1)n2c3ccccc3c4nc5ccccc5nc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N03 compound treatment 283.0 95.8 0.5 280.7 96.3 0.5 0.7074 1.0 1948880 ChemDiv1_007681 C/C(=C\C(=O)C(F)(F)F)/Nc1ccc(cc1)C(=O)N2N=C(C)CC2(O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N04 compound treatment 277.7 90.5 0.47 279.2 94.8 0.49 0.6824 0.9998 1328098 ChemDiv1_007682 COc1cc(C)nc(n1)N(CCC(C)C)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N05 compound treatment 281.1 93.9 0.49 273.0 88.6 0.46 0.6721 0.9995 1929023 ChemDiv1_007683 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N06 compound treatment 281.2 94.0 0.49 277.7 93.3 0.49 0.6897 1.0 1718351 ChemDiv1_007684 Cc1ccc2nsnc2c1NC(=O)c3ccc4OCCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N07 compound treatment 279.3 92.1 0.48 274.2 89.8 0.47 0.6699 0.9999 1579384 ChemDiv1_007685 COc1ccc(CC(=O)N2N=C(C)CC2(O)c3ccc(Cl)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N08 compound treatment 280.6 93.4 0.49 272.7 88.3 0.46 0.6692 0.9996 1427928 ChemDiv1_007686 Cc1cc2nc(Cc3ccc(F)c(F)c3)c(=O)n(C)c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N09 compound treatment 281.8 94.6 0.49 280.7 96.3 0.5 0.703 1.0 1517402 ChemDiv1_007687 CCC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N10 compound treatment 276.1 88.9 0.46 276.3 91.9 0.48 0.6658 0.9999 1547297 ChemDiv1_007688 COc1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccc(C)cc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N11 compound treatment 276.7 89.5 0.47 271.8 87.4 0.45 0.6515 0.9999 1939182 ChemDiv1_007689 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(Br)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N12 compound treatment 276.0 88.8 0.46 281.4 97.0 0.5 0.6842 0.9991 1252722 ChemDiv1_007690 CCOC(=O)c1sc2nc(C)nc(Nc3ccc(OC)cc3OC)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N13 compound treatment 276.8 89.6 0.47 280.2 95.8 0.5 0.6827 0.9995 1973953 ChemDiv1_007691 Cc1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N14 compound treatment 278.8 91.6 0.48 276.6 92.2 0.48 0.6769 1.0 1457913 ChemDiv1_007692 Cc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N15 compound treatment 279.2 92.0 0.48 274.7 90.3 0.47 0.6713 0.9999 1951819 ChemDiv1_007693 COc1cccc(c1)C2=NN(C(=O)c3cccc(c3)[N+](=O)[O-])C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N16 compound treatment 273.6 86.4 0.45 275.8 91.4 0.48 0.6547 0.9997 1179871 ChemDiv1_007694 CCOC(=O)c1sc2nc(C)nc(OCc3ccccc3Cl)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N17 compound treatment 279.9 92.7 0.48 277.5 93.1 0.48 0.6842 1.0 1683227 ChemDiv1_007695 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nccn3C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N18 compound treatment 279.1 91.9 0.48 275.4 91.0 0.47 0.6735 1.0 1175410 ChemDiv1_007696 Clc1ccccc1NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N19 compound treatment 278.9 91.7 0.48 277.1 92.7 0.48 0.6791 1.0 1973954 ChemDiv1_007697 COC(=O)c1ccc(cc1)N2N=C(C)/C(=C/c3ccc(o3)c4cccc(c4)C(=O)O)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N20 compound treatment 276.7 89.5 0.47 275.3 90.9 0.47 0.6643 1.0 1973955 ChemDiv1_007698 CCOC(=O)c1sc2nc(C)nc(NCCCN3CCOCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N21 compound treatment 277.8 90.6 0.47 275.3 90.9 0.47 0.6684 1.0 1196056 ChemDiv1_007699 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N22 compound treatment 276.6 89.4 0.47 273.8 89.4 0.46 0.6584 1.0 1497498 ChemDiv1_007700 COc1cc(cc(OC)c1OC)c2nc(N3CCN(C)CC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N23 mock treatment 284.6 97.4 0.51 275.1 90.7 0.47 0.6927 0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 N24 mock treatment 194.3 7.11 0.04 184.3 -0.0844 0.0 0.0259 0.6987 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O01 compound treatment 281.1 93.9 0.49 283.2 98.8 0.51 0.7096 0.9997 1973956 ChemDiv1_007701 CCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O02 compound treatment 280.8 93.6 0.49 278.0 93.6 0.49 0.6894 1.0 1251746 ChemDiv1_007702 Cn1c(=O)c(Cc2ccccc2Cl)nc3cc(ccc13)C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O03 compound treatment 282.4 95.2 0.5 276.0 91.6 0.48 0.6879 0.9998 1371125 ChemDiv1_007703 Cc1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O04 compound treatment 282.3 95.1 0.5 276.7 92.3 0.48 0.6901 0.9999 1973957 ChemDiv1_007704 CCOC(=O)C1=C(N)OC2=C(C1c3cc([N+](=O)[O-])c(C)s3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O05 compound treatment 281.9 94.7 0.49 273.7 89.3 0.46 0.6776 0.9995 1380249 ChemDiv1_007705 COc1nc(Oc2ccc(cc2)C(=O)OCC(=O)N)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O06 compound treatment 279.7 92.5 0.48 274.5 90.1 0.47 0.6725 0.9999 1534647 ChemDiv1_007706 CN1CCN(CC1)C(=O)c2ccc3OCCOc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O07 compound treatment 275.5 88.3 0.46 278.8 94.4 0.49 0.6728 0.9995 1784490 ChemDiv1_007707 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4cccc(c4)[N+](=O)[O-])C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O08 compound treatment 277.0 89.8 0.47 274.5 90.1 0.47 0.6625 1.0 1742218 ChemDiv1_007708 COc1cccc(C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O09 compound treatment 277.5 90.3 0.47 278.6 94.2 0.49 0.6794 0.9998 1940927 ChemDiv1_007709 CCCCN(CN1C(=O)C2CC=C(Cl)CC2C1=O)CN3C(=O)C4CC=C(Cl)CC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O10 compound treatment 279.3 92.1 0.48 276.8 92.4 0.48 0.6794 1.0 1973958 ChemDiv1_007710 COc1ccc(cc1)C2=NN(C(C2)c3cc(OC)ccc3OC)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O11 compound treatment 275.8 88.6 0.46 276.3 91.9 0.48 0.6647 0.9999 1279536 ChemDiv1_007711 O=C(CSc1nnc[nH]1)n2c3CCCCc3c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O12 compound treatment 278.4 91.2 0.48 276.4 92.0 0.48 0.6746 1.0 1294923 ChemDiv1_007712 OC(=O)CCCC(=O)N1N=C(CC1c2ccccc2F)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O13 compound treatment 287.8 101.0 0.52 285.8 101.0 0.53 0.7439 1.0 1973959 ChemDiv1_007713 [O-][N+](=O)c1ccc(c2ccc(o2)c3nc4sc5CCCCc5c4c(=O)[nH]3)c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O14 compound treatment 274.0 86.8 0.45 275.0 90.6 0.47 0.6533 0.9998 1195752 ChemDiv1_007714 CCC1CCC(=O)C(C1)C2(O)C(=O)Nc3ccccc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O15 compound treatment 281.6 94.4 0.49 280.6 96.2 0.5 0.7019 1.0 1973960 ChemDiv1_007715 CCOc1cc(ccc1OCCOCCOc2ccccc2C)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O16 compound treatment 277.2 90.0 0.47 276.8 92.4 0.48 0.6717 0.9999 1973961 ChemDiv1_007716 CCC1=NN(C(=O)Cc2ccc(OC)c(OC)c2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O17 compound treatment 278.5 91.3 0.48 276.5 92.1 0.48 0.6754 1.0 1715441 ChemDiv1_007717 CC(C(=O)c1ccccc1)C2(O)C(=O)Nc3ccc(Br)cc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O18 compound treatment 281.4 94.2 0.49 274.8 90.4 0.47 0.6798 0.9998 1973962 ChemDiv1_007718 CCCCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O19 compound treatment 279.6 92.4 0.48 275.3 90.9 0.47 0.675 1.0 1973963 ChemDiv1_007719 FC(F)(F)c1cccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O20 compound treatment 273.2 86.0 0.45 278.5 94.1 0.49 0.6632 0.9991 1927750 ChemDiv1_007720 CC1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O21 compound treatment 278.1 90.9 0.47 279.8 95.4 0.5 0.686 0.9997 1156166 ChemDiv1_007721 CCOC(=O)c1nc(Nc2ccc3CCCc3c2)c4ccccc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O22 compound treatment 274.9 87.7 0.46 272.0 87.6 0.46 0.6456 1.0 1386793 ChemDiv1_007722 CCOC(=O)C1=NN(C(=O)CCc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O23 mock treatment 281.3 94.1 0.49 278.3 93.9 0.49 0.6923 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 O24 mock treatment 93.0 -94.2 -0.49 96.9 -87.5 -0.45 -0.669 -0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P01 compound treatment 282.5 95.3 0.5 284.9 101.0 0.52 0.721 0.9997 1948577 ChemDiv1_007723 OC1(CC(=NN1C(=O)c2ccncc2)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P02 compound treatment 285.7 98.5 0.51 281.8 97.4 0.51 0.7214 1.0 1515753 ChemDiv1_007724 CCOC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P03 compound treatment 279.8 92.6 0.48 282.6 98.2 0.51 0.7026 0.9996 1973964 ChemDiv1_007725 CCCC1=NN(C(=O)c2ccc(cc2)C(C)(C)C)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P04 compound treatment 285.8 98.6 0.51 283.1 98.7 0.51 0.7266 1.0 1973965 ChemDiv1_007726 CCOC(=O)c1c(NC(=O)CC2S/C(=N/C)/N(C)C2=O)sc3CCCCc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P05 compound treatment 279.4 92.2 0.48 274.4 90.0 0.47 0.671 0.9999 1948910 ChemDiv1_007727 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P06 compound treatment 279.8 92.6 0.48 279.8 95.4 0.5 0.6923 0.9999 1253147 ChemDiv1_007728 O=C(N1C(=O)c2ccccc2S1(=O)=O)c3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P07 compound treatment 282.8 95.6 0.5 285.6 101.0 0.53 0.7247 0.9996 1574959 ChemDiv1_007729 CC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P08 compound treatment 277.4 90.2 0.47 278.9 94.5 0.49 0.6801 0.9998 1547213 ChemDiv1_007730 COc1ccc(NC(=O)Cn2c(nc3sc(C)c(C)c3c2=O)c4ccccc4Cl)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P09 compound treatment 278.3 91.1 0.48 279.8 95.4 0.5 0.6868 0.9998 1169643 ChemDiv1_007731 CCC1=NN(C(=O)c2cccc(OC)c2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P10 compound treatment 275.4 88.2 0.46 277.7 93.3 0.49 0.6684 0.9997 1493554 ChemDiv1_007732 CN(C)c1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P11 compound treatment 286.1 98.9 0.52 287.3 103.0 0.53 0.7431 0.9998 1942893 ChemDiv1_007733 COc1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P12 compound treatment 280.7 93.5 0.49 276.3 91.9 0.48 0.6828 0.9999 1431171 ChemDiv1_007734 CCOC(=O)c1sc2nc(C)nc(Nc3cc(Cl)ccc3OC)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P13 compound treatment 280.3 93.1 0.49 273.4 89.0 0.46 0.6706 0.9997 1973966 ChemDiv1_007735 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(F)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P14 compound treatment 282.5 95.3 0.5 280.7 96.3 0.5 0.7056 1.0 1683228 ChemDiv1_007736 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(OCC)cc3)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P15 compound treatment 283.4 96.2 0.5 284.2 99.8 0.52 0.7218 0.9999 1973967 ChemDiv1_007737 COc1cccc(c1)C2=NN(C(=O)c3ccccc3)C(O)(C2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P16 compound treatment 281.1 93.9 0.49 274.6 90.2 0.47 0.678 0.9998 1639138 ChemDiv1_007738 COc1cccc(NC(=O)Cn2c(nc3sc4CCCCc4c3c2=O)c5cccc(OC)c5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P17 compound treatment 274.7 87.5 0.46 273.5 89.1 0.46 0.6503 1.0 1529119 ChemDiv1_007739 O=C1CCCC2=C1C(C3=C(CCCC3=O)O2)c4ccc(OCc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P18 compound treatment 277.9 90.7 0.47 279.2 94.8 0.49 0.6831 0.9998 1244524 ChemDiv1_007740 Fc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c(F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P19 compound treatment 278.7 91.5 0.48 281.3 96.9 0.5 0.6938 0.9996 1973968 ChemDiv1_007741 COC(=O)c1ccc(cc1)N2N=C(C)/C(=C/c3ccc(o3)c4ccc(cc4)S(=O)(=O)N)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P20 compound treatment 280.6 93.4 0.49 279.5 95.1 0.49 0.6941 1.0 1452350 ChemDiv1_007742 CCOC(=O)C1CCN(CC1)c2nc(nc3ccccc23)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P21 compound treatment 348.8 162.0 0.84 342.7 158.0 0.82 1.178 0.9999 1480386 ChemDiv1_007743 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)cc3)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P22 compound treatment 278.1 90.9 0.47 277.0 92.6 0.48 0.6757 1.0 1533549 ChemDiv1_007744 COc1cc(cc(OC)c1OC)c2nc(N3CCCC(C)C3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P23 mock treatment 281.9 94.7 0.49 281.0 96.6 0.5 0.7045 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.608 P24 mock treatment 92.3 -94.9 -0.5 78.9 -105.0 -0.55 -0.7377 -0.9987 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A01 compound treatment 283.2 96.1 0.5 310.0 109.0 0.57 0.754 0.9982 1973969 ChemDiv1_007745 CCOC(=O)c1sc2nc(C)nc(NC3CCCCC3C)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A02 compound treatment 281.1 94.0 0.49 304.9 104.0 0.54 0.7275 0.9989 1161400 ChemDiv1_007746 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccccc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A03 compound treatment 281.4 94.3 0.49 308.4 107.0 0.56 0.7415 0.9981 1589242 ChemDiv1_007747 COc1cc(cc(OC)c1OC)c2nc(N3CCCCC3C)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A04 compound treatment 281.0 93.9 0.49 306.1 105.0 0.54 0.7315 0.9986 1973970 ChemDiv1_007748 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCC(CC4)(N5CCCCC5)C(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A05 compound treatment 276.5 89.4 0.47 305.0 104.0 0.54 0.7109 0.9974 1973971 ChemDiv1_007749 CCOC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A06 compound treatment 276.5 89.4 0.47 305.9 105.0 0.54 0.7142 0.9971 1640109 ChemDiv1_007750 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)Nc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A07 compound treatment 277.2 90.1 0.47 306.6 105.0 0.55 0.7194 0.9971 1235052 ChemDiv1_007751 CCOC(=O)c1sc2nc(Cc3ccccc3)nc(NCc4cccs4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A08 compound treatment 275.8 88.7 0.46 299.7 98.4 0.51 0.6888 0.9988 1726292 ChemDiv1_007752 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A09 compound treatment 275.2 88.1 0.46 304.3 103.0 0.54 0.7035 0.9971 1242161 ChemDiv1_007753 COC(=O)Cc1nc(N2CCN(CC2)c3ccc(OC)cc3)c4c(C)c(C)sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A10 compound treatment 273.8 86.7 0.45 300.4 99.1 0.52 0.684 0.9979 1286169 ChemDiv1_007754 CN(c1ccccc1)c2ncnc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A11 compound treatment 278.8 91.7 0.48 303.1 102.0 0.53 0.7124 0.9987 1973972 ChemDiv1_007755 CCOC(=O)c1sc2nc(CC(=O)OC)nc(Nc3cc(OC)ccc3OC)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A12 compound treatment 277.5 90.4 0.47 299.9 98.6 0.51 0.6958 0.9991 1399331 ChemDiv1_007756 COc1ccccc1N2CCN(CC2)c3ncnc4sc(C(=O)O)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A13 compound treatment 276.7 89.6 0.47 294.3 93.0 0.48 0.6723 0.9999 1973973 ChemDiv1_007757 CCOC(=O)c1sc2nc(CC(=O)OC)nc(Nc3cc(ccc3OC)[N+](=O)[O-])c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A14 compound treatment 274.0 86.9 0.45 298.2 96.9 0.5 0.6767 0.9986 1973974 ChemDiv1_007758 Cc1c(sc2ncn(CC(=O)N3CCOCC3)c(=O)c12)C(=O)N4CCN(CC4)c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A15 compound treatment 274.8 87.7 0.46 300.6 99.3 0.52 0.6885 0.9982 1257391 ChemDiv1_007759 CCOC(=O)N1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A16 compound treatment 280.6 93.5 0.49 296.9 95.6 0.5 0.6963 1.0 1973975 ChemDiv1_007760 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC(CC5)(N6CCCCC6)C(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A17 compound treatment 273.0 85.9 0.45 299.2 97.9 0.51 0.6767 0.998 1421175 ChemDiv1_007761 CCOC(=O)N1CCN(CC1)c2nc(nc3sc4CCCCc4c23)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A18 compound treatment 275.7 88.6 0.46 296.4 95.1 0.49 0.6763 0.9994 1709068 ChemDiv1_007762 CCN(CC)c1ncnc2sc(C(=O)O)c(C)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A19 compound treatment 278.0 90.9 0.47 298.7 97.4 0.51 0.6933 0.9995 1290203 ChemDiv1_007763 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)O)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A20 compound treatment 274.0 86.9 0.45 294.9 93.6 0.49 0.6646 0.9994 1702776 ChemDiv1_007764 CC1CC(C)CN(C1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A21 compound treatment 278.3 91.2 0.48 295.8 94.5 0.49 0.6837 0.9999 1973976 ChemDiv1_007765 CCN(CC)C(=O)Cn1cnc2sc(C(=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c(C)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A22 compound treatment 280.8 93.7 0.49 292.3 91.0 0.47 0.6801 0.9999 1589509 ChemDiv1_007766 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A23 mock treatment 280.7 93.6 0.49 294.9 93.6 0.49 0.6893 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 A24 mock treatment 73.9 -113.0 -0.59 86.5 -115.0 -0.6 -0.8395 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B01 compound treatment 285.9 98.8 0.52 310.7 109.0 0.57 0.7665 0.9988 1218261 ChemDiv1_007767 CCOc1ccc(NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B02 compound treatment 275.3 88.2 0.46 303.8 102.0 0.53 0.7021 0.9973 1584145 ChemDiv1_007768 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)C5CC=CCC5C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B03 compound treatment 280.2 93.1 0.49 309.4 108.0 0.56 0.7407 0.9974 1712141 ChemDiv1_007769 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B04 compound treatment 288.1 101.0 0.53 313.9 113.0 0.59 0.7864 0.9986 1864947 ChemDiv1_007770 COc1cc(ccc1O)C(=O)NN2C(=O)/C(=C/3\C(=O)Nc4ccccc34)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B05 compound treatment 275.4 88.3 0.46 302.9 102.0 0.53 0.6991 0.9977 1482540 ChemDiv1_007771 CN(Cc1ccccc1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B06 compound treatment 278.7 91.6 0.48 307.1 106.0 0.55 0.7267 0.9975 1727301 ChemDiv1_007772 O=C(CC1SC(=O)N(CN2CCOCC2)C1=O)Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B07 compound treatment 275.7 88.6 0.46 307.5 106.0 0.55 0.7171 0.9961 1463494 ChemDiv1_007773 CCOC(=O)C1CCCCN1C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B08 compound treatment 278.6 91.5 0.48 302.3 101.0 0.52 0.7087 0.9989 1973977 ChemDiv1_007774 Brc1cnc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B09 compound treatment 278.5 91.4 0.48 303.8 102.0 0.53 0.7139 0.9985 1203166 ChemDiv1_007775 CCCNC(=O)Cn1cnc2sc(C(=O)O)c(C)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B10 compound treatment 279.3 92.2 0.48 300.7 99.4 0.52 0.7054 0.9994 1973978 ChemDiv1_007776 CCC1C(=O)NC(=NC1=O)SCc2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B11 compound treatment 277.7 90.6 0.47 298.7 97.4 0.51 0.6922 0.9994 1973979 ChemDiv1_007777 CCN1CCN(CC1)C(=O)c2sc3ncnc(N4CCCCC4C)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B12 compound treatment 275.0 87.9 0.46 305.8 104.0 0.54 0.7083 0.9964 1973980 ChemDiv1_007778 CCN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(Cl)cc4)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B13 compound treatment 277.4 90.3 0.47 300.5 99.2 0.52 0.6977 0.999 1973981 ChemDiv1_007779 CC1CCCCN1c2ncnc3sc(C(=O)NCC4COc5ccccc5O4)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B14 compound treatment 272.2 85.1 0.44 298.5 97.2 0.51 0.6711 0.9979 1222385 ChemDiv1_007780 CCC(=O)N1N=C(CC1c2ccc(cc2)N(C)C)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B15 compound treatment 269.1 82.0 0.43 300.6 99.3 0.52 0.6674 0.9956 1973982 ChemDiv1_007781 CCn1c(C(=O)O)c(CC(=O)Nc2cc(Cl)c(OC)cc2OC)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B16 compound treatment 273.0 85.9 0.45 299.0 97.7 0.51 0.6759 0.9981 1668199 ChemDiv1_007782 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B17 compound treatment 276.4 89.3 0.47 297.0 95.7 0.5 0.6811 0.9995 1973983 ChemDiv1_007783 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3ccc(F)cc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B18 compound treatment 283.3 96.2 0.5 303.5 102.0 0.53 0.7305 0.9996 1611007 ChemDiv1_007784 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B19 compound treatment 273.7 86.6 0.45 294.4 93.1 0.48 0.6616 0.9994 1973984 ChemDiv1_007785 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3cccc(Cl)c3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B20 compound treatment 300.2 113.0 0.59 317.5 116.0 0.6 0.8443 0.9999 1612101 ChemDiv1_007786 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(cc3)N(C)C)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B21 compound treatment 275.7 88.6 0.46 297.5 96.2 0.5 0.6804 0.9992 1787042 ChemDiv1_007787 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCNCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B22 compound treatment 278.2 91.1 0.48 295.8 94.5 0.49 0.6834 0.9999 1973985 ChemDiv1_007788 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B23 mock treatment 280.4 93.3 0.49 295.6 94.3 0.49 0.6907 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 B24 mock treatment 74.0 -113.0 -0.59 89.9 -111.0 -0.58 -0.8267 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C01 compound treatment 283.0 95.9 0.5 311.7 110.0 0.57 0.7595 0.9977 1147452 ChemDiv1_007789 CCOC(=O)c1sc2nc(C)nc(N3CCc4ccccc4C3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C02 compound treatment 283.6 96.5 0.5 308.2 107.0 0.56 0.7489 0.9988 1973986 ChemDiv1_007790 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C03 compound treatment 282.2 95.1 0.5 309.4 108.0 0.56 0.7481 0.9981 1473475 ChemDiv1_007791 Cc1cccc(c1)c2nc(NCc3ccc4OCOc4c3)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C04 compound treatment 279.8 92.7 0.48 304.1 103.0 0.53 0.7198 0.9988 1224788 ChemDiv1_007792 CC1CN(CCN1c2ccc(C)cc2)C(=O)c3sc4nc(C)nc(N5CCOCC5)c4c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C05 compound treatment 277.1 90.0 0.47 303.6 102.0 0.53 0.708 0.9981 1430556 ChemDiv1_007793 COc1ccc(CCNc2nc(C)nc3sc4CCCCc4c23)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C06 compound treatment 278.0 90.9 0.47 305.6 104.0 0.54 0.7186 0.9978 1442537 ChemDiv1_007794 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCN(Cc5ccccc5)CC4)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C07 compound treatment 278.6 91.5 0.48 306.6 105.0 0.55 0.7245 0.9977 1973987 ChemDiv1_007795 Cc1ccc(cc1)c2nc(N3CCC(CC3)(N4CCCCC4)C(=O)N)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C08 compound treatment 277.1 90.0 0.47 306.8 105.0 0.55 0.7197 0.997 1973988 ChemDiv1_007796 CCOC(=O)CNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C09 compound treatment 273.1 86.0 0.45 300.6 99.3 0.52 0.6822 0.9976 1719553 ChemDiv1_007797 COC(=O)Cc1nc(N2CCN(Cc3ccccc3)CC2)c4c(C)c(C)sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C10 compound treatment 276.6 89.5 0.47 304.1 103.0 0.53 0.708 0.9977 1412683 ChemDiv1_007798 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCCN5CCOCC5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C11 compound treatment 274.8 87.7 0.46 298.3 97.0 0.5 0.68 0.9988 1211676 ChemDiv1_007799 CCOC(=O)c1sc2nc(CC(=O)OC)nc(Nc3ccccc3OCC)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C12 compound treatment 274.2 87.1 0.45 301.1 99.8 0.52 0.6881 0.9978 1696399 ChemDiv1_007800 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C13 compound treatment 276.3 89.2 0.47 300.0 98.7 0.51 0.6918 0.9988 1230747 ChemDiv1_007801 CCOC(=O)c1sc2ncn(CC(=O)N(CC)CC)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C14 compound treatment 282.4 95.3 0.5 298.7 97.4 0.51 0.7095 1.0 1376308 ChemDiv1_007802 CCN(CC)C(=O)Cn1cnc2sc(C(=O)N3CCN(Cc4ccc5OCOc5c4)CC3)c(C)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C15 compound treatment 277.4 90.3 0.47 300.2 98.9 0.51 0.6966 0.999 1720238 ChemDiv1_007803 CCCCN(CC)C(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C16 compound treatment 276.4 89.3 0.47 298.6 97.3 0.51 0.687 0.9992 1647635 ChemDiv1_007804 CCOC(=O)N1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C17 compound treatment 274.7 87.6 0.46 296.3 95.0 0.49 0.6723 0.9993 1361082 ChemDiv1_007805 CCCN1CCN(CC1)c2nc(nc3sc4CCCCc4c23)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C18 compound treatment 272.5 85.4 0.45 297.9 96.6 0.5 0.6701 0.9982 1973989 ChemDiv1_007806 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC(CC5)(N6CCCCC6)C(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C19 compound treatment 277.8 90.7 0.47 300.1 98.8 0.51 0.6977 0.9992 1973990 ChemDiv1_007807 CCOC(=O)c1nc(N2CCC(CC2)(N3CCCCC3)C(=O)N)c4c5CCCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C20 compound treatment 271.9 84.8 0.44 295.6 94.3 0.49 0.6594 0.9987 1537236 ChemDiv1_007808 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccc(F)cc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C21 compound treatment 277.5 90.4 0.47 296.6 95.3 0.5 0.6837 0.9997 1973991 ChemDiv1_007809 Cc1c(sc2ncn(CC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C22 compound treatment 278.3 91.2 0.48 300.6 99.3 0.52 0.7014 0.9992 1973992 ChemDiv1_007810 Fc1ccccc1c2nc(NCc3cccs3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C23 mock treatment 285.8 98.7 0.51 299.0 97.7 0.51 0.7232 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 C24 mock treatment 78.8 -108.0 -0.56 90.1 -111.0 -0.58 -0.8082 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D01 compound treatment 282.7 95.6 0.5 311.2 110.0 0.57 0.7566 0.9977 1400070 ChemDiv1_007811 COc1ccc(OC)c(NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D02 compound treatment 283.0 95.9 0.5 308.1 107.0 0.56 0.7463 0.9987 1554058 ChemDiv1_007812 CC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(C)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D03 compound treatment 277.5 90.4 0.47 304.0 103.0 0.53 0.7109 0.9981 1973993 ChemDiv1_007813 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)Nc5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D04 compound treatment 280.0 92.9 0.48 303.9 103.0 0.53 0.7198 0.9989 1973994 ChemDiv1_007814 COc1cc(ccc1O)C(=O)NN2C(=O)/C(=C/3\C(=O)Nc4cc(Br)ccc34)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D05 compound treatment 274.6 87.5 0.46 299.2 97.9 0.51 0.6826 0.9985 1735640 ChemDiv1_007815 CN(CCc1ccccn1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D06 compound treatment 286.9 99.8 0.52 303.6 102.0 0.53 0.7441 0.9999 1973995 ChemDiv1_007816 Brc1ccc(NC(=O)CCSc2nc3ccccc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D07 compound treatment 274.7 87.6 0.46 302.3 101.0 0.52 0.6943 0.9976 1973996 ChemDiv1_007817 Cc1cc(NC(=O)c2nn(c3ccc(Cl)cc3)c(=O)c4ccccc24)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D08 compound treatment 277.8 90.7 0.47 305.1 104.0 0.54 0.7161 0.9979 1973997 ChemDiv1_007818 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)Nc3ccccc3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D09 compound treatment 278.2 91.1 0.48 301.2 99.9 0.52 0.7032 0.999 1548782 ChemDiv1_007819 CC(C)c1ccc(NC(=O)Cn2cnc3sc(C(=O)O)c(C)c3c2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D10 compound treatment 276.9 89.8 0.47 301.1 99.8 0.52 0.698 0.9987 1730627 ChemDiv1_007820 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D11 compound treatment 277.2 90.1 0.47 297.9 96.6 0.5 0.6874 0.9995 1973998 ChemDiv1_007821 CCOC(=O)N1CCN(CC1)C(=O)CNC(=O)Cn2cnc3sc4CCCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D12 compound treatment 276.3 89.2 0.47 302.3 101.0 0.52 0.7002 0.9982 1973999 ChemDiv1_007822 COc1ccc(Oc2c(oc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D13 compound treatment 276.7 89.6 0.47 306.4 105.0 0.55 0.7168 0.997 1974000 ChemDiv1_007823 CCN(CCCNC(=O)c1sc2ncn(CC(=O)N3CCCCC3C)c(=O)c2c1C)Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D14 compound treatment 283.7 96.6 0.5 301.2 99.9 0.52 0.7235 0.9999 1974001 ChemDiv1_007824 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D15 compound treatment 278.4 91.3 0.48 299.7 98.4 0.51 0.6984 0.9994 1974002 ChemDiv1_007825 CCn1c(C(=O)O)c(CC(=O)Nc2ccc(Br)cc2C)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D16 compound treatment 277.7 90.6 0.47 296.6 95.3 0.5 0.6845 0.9997 1217947 ChemDiv1_007826 COc1ccc(cc1OC)C2CC(=NN2C(=O)C)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D17 compound treatment 272.7 85.6 0.45 301.5 100.0 0.52 0.684 0.9971 1974003 ChemDiv1_007827 CCn1c(C(=O)O)c(CC(=O)N(C)c2ccc(Br)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D18 compound treatment 272.4 85.3 0.44 300.3 99.0 0.51 0.6785 0.9974 1598143 ChemDiv1_007828 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D19 compound treatment 274.7 87.6 0.46 291.6 90.3 0.47 0.655 0.9999 1974004 ChemDiv1_007829 CCN(CC)CCNC(=O)c1sc2ncnc(N3CCCCC3C)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D20 compound treatment 284.4 97.3 0.51 308.5 107.0 0.56 0.7529 0.9989 1403804 ChemDiv1_007830 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D21 compound treatment 277.9 90.8 0.47 298.6 97.3 0.51 0.6925 0.9995 1974005 ChemDiv1_007831 CC(C)(C)OC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(ccc4n2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D22 compound treatment 276.3 89.2 0.47 298.6 97.3 0.51 0.6866 0.9991 1190373 ChemDiv1_007832 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4cccc(C)c4nc3Cl)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D23 mock treatment 280.1 93.0 0.49 298.0 96.7 0.5 0.6985 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 D24 mock treatment 81.4 -106.0 -0.55 91.4 -110.0 -0.57 -0.7939 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E01 compound treatment 287.4 100.0 0.52 316.5 115.0 0.6 0.7934 0.9977 1712359 ChemDiv1_007833 COc1ccc(cc1OC)c2nc(NCc3ccc(F)cc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E02 compound treatment 282.2 95.1 0.5 306.3 105.0 0.55 0.7367 0.9989 1729639 ChemDiv1_007834 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCC(C)CC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E03 compound treatment 283.3 96.2 0.5 305.3 104.0 0.54 0.7371 0.9993 1974006 ChemDiv1_007835 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)c3ncnc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E04 compound treatment 279.2 92.1 0.48 305.7 104.0 0.54 0.7234 0.9982 1293523 ChemDiv1_007836 Cc1c(sc2nc(C)nc(N3CCCCC3)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E05 compound treatment 281.4 94.3 0.49 304.6 103.0 0.54 0.7275 0.999 1247213 ChemDiv1_007837 CCOC(=O)c1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E06 compound treatment 284.1 97.0 0.51 306.6 105.0 0.55 0.7448 0.9992 1974007 ChemDiv1_007838 CC(C)c1ccc(NC(=O)c2sc3ncn(CC(=O)Nc4cccc(c4)C(F)(F)F)c(=O)c3c2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E07 compound treatment 276.5 89.4 0.47 305.4 104.0 0.54 0.7124 0.9973 1380258 ChemDiv1_007839 CCOC(CNc1nc(nc2ccccc12)c3ccc(C)cc3)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E08 compound treatment 283.9 96.8 0.5 306.0 105.0 0.54 0.7419 0.9993 1680197 ChemDiv1_007840 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)Nc5ccc6OCOc6c5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E09 compound treatment 280.2 93.1 0.49 299.6 98.3 0.51 0.7047 0.9997 1513233 ChemDiv1_007841 COC(=O)Cc1nc(N2CCN(Cc3ccc4OCOc4c3)CC2)c5c(C)c(C)sc5n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E10 compound treatment 275.7 88.6 0.46 300.6 99.3 0.52 0.6918 0.9985 1675995 ChemDiv1_007842 CCOC(=O)C1CCCN(C1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E11 compound treatment 280.4 93.3 0.49 299.9 98.6 0.51 0.7065 0.9997 1660744 ChemDiv1_007843 CCOC(=O)CNc1nc(CC(=O)OC)nc2sc(C(=O)OCC)c(C)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E12 compound treatment 273.8 86.7 0.45 298.2 96.9 0.5 0.6759 0.9986 1121035 ChemDiv1_007844 COc1cc(Cl)c(C)cc1NC(=O)c2sc3ncn(CC(=O)Nc4ccc(C)c(Cl)c4)c(=O)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E13 compound treatment 278.8 91.7 0.48 302.7 101.0 0.53 0.7109 0.9988 1480042 ChemDiv1_007845 CCOc1ccc(NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E14 compound treatment 264.0 76.9 0.4 302.7 101.0 0.53 0.6563 0.9909 1539940 ChemDiv1_007846 CCN(CC)c1nc(C)nc2sc(C(=O)O)c(C)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E15 compound treatment 272.5 85.4 0.45 297.9 96.6 0.5 0.6701 0.9982 1604567 ChemDiv1_007847 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E16 compound treatment 276.8 89.7 0.47 299.5 98.2 0.51 0.6918 0.9991 1117891 ChemDiv1_007848 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccccc6F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E17 compound treatment 274.6 87.5 0.46 299.2 97.9 0.51 0.6826 0.9985 1974008 ChemDiv1_007849 CCOC(CNC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E18 compound treatment 278.0 90.9 0.47 297.4 96.1 0.5 0.6885 0.9997 1974009 ChemDiv1_007850 COc1ccccc1N2CCN(CC2)C(=O)c3sc4ncnc(N5CCN(CC5)c6ccccn6)c4c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E19 compound treatment 276.1 89.0 0.46 295.0 93.7 0.49 0.6727 0.9997 1974010 ChemDiv1_007851 CCOC(=O)c1nc(N2CCC3(CC2)OCCO3)c4c5CCCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E20 compound treatment 270.6 83.5 0.44 298.2 96.9 0.5 0.6641 0.9974 1659096 ChemDiv1_007852 COc1ccc(C)cc1NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E21 compound treatment 272.5 85.4 0.45 300.2 98.9 0.51 0.6785 0.9975 1263937 ChemDiv1_007853 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)NCc4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E22 compound treatment 277.2 90.1 0.47 297.2 95.9 0.5 0.6848 0.9996 1390036 ChemDiv1_007854 CCN1CCN(CC1)c2ncnc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E23 mock treatment 280.9 93.8 0.49 292.1 90.8 0.47 0.6797 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 E24 mock treatment 77.2 -110.0 -0.57 88.9 -112.0 -0.58 -0.8185 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F01 compound treatment 284.0 96.9 0.51 307.9 107.0 0.55 0.7492 0.9989 1974011 ChemDiv1_007855 COc1ccc(cc1NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F02 compound treatment 280.1 93.0 0.49 306.1 105.0 0.54 0.7282 0.9983 1787043 ChemDiv1_007856 OC(=O)C1CC=CCC1C(=O)N2CCN(CC2)c3nc(c4ccccc4)c5cc(ccc5n3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F03 compound treatment 279.0 91.9 0.48 304.0 103.0 0.53 0.7164 0.9986 1428168 ChemDiv1_007857 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)NCc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F04 compound treatment 279.9 92.8 0.48 307.0 106.0 0.55 0.7308 0.998 1781461 ChemDiv1_007858 Cc1c(N2C(=O)S/C(=C\3/C(=O)Nc4ccccc34)/C2=O)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F05 compound treatment 279.3 92.2 0.48 303.0 102.0 0.53 0.7139 0.9989 1547203 ChemDiv1_007859 CC1CCCCN1c2ncnc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F06 compound treatment 278.6 91.5 0.48 306.8 105.0 0.55 0.7253 0.9976 1974012 ChemDiv1_007860 Brc1ccccc1NC(=O)CCSc2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F07 compound treatment 279.7 92.6 0.48 299.9 98.6 0.51 0.704 0.9996 1974013 ChemDiv1_007861 CN(C1CCCCC1)C(=O)c2nn(c3ccc(Cl)cc3)c(=O)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F08 compound treatment 281.5 94.4 0.49 306.2 105.0 0.55 0.7338 0.9987 1974014 ChemDiv1_007862 Brc1ccc(cc1)c2csc(NC(=O)CSC3=NC(=O)C(Cc4ccccc4)C(=O)N3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F09 compound treatment 273.7 86.6 0.45 304.2 103.0 0.53 0.6976 0.9965 1974015 ChemDiv1_007863 CN1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCN(CC4)c5cccc(Cl)c5)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F10 compound treatment 277.9 90.8 0.47 302.9 102.0 0.53 0.7083 0.9985 1383669 ChemDiv1_007864 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCCCC4)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F11 compound treatment 273.9 86.8 0.45 302.6 101.0 0.53 0.6925 0.9972 1974016 ChemDiv1_007865 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCC(=O)N4CCN(Cc5ccccc5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F12 compound treatment 284.2 97.1 0.51 307.1 106.0 0.55 0.747 0.9992 1146438 ChemDiv1_007866 Cc1cccc(Oc2coc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F13 compound treatment 279.2 92.1 0.48 299.8 98.5 0.51 0.7017 0.9995 1974017 ChemDiv1_007867 CCCN1CCN(CC1)c2ncnc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F14 compound treatment 274.9 87.8 0.46 301.3 100.0 0.52 0.6914 0.998 1723164 ChemDiv1_007868 CC(=O)N1N=C(CC1c2ccccn2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F15 compound treatment 278.0 90.9 0.47 302.1 101.0 0.52 0.7058 0.9988 1606258 ChemDiv1_007869 CCOC(=O)c1sc2ncn(CC(=O)N3CCCCC3C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F16 compound treatment 275.5 88.4 0.46 297.6 96.3 0.5 0.68 0.9992 1705842 ChemDiv1_007870 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F17 compound treatment 272.8 85.7 0.45 303.7 102.0 0.53 0.6925 0.9962 1974018 ChemDiv1_007871 CCn1c(C(=O)O)c(CC(=O)N(C)c2cccc(c2)C(F)(F)F)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F18 compound treatment 283.7 96.6 0.5 306.2 105.0 0.55 0.7419 0.9992 1485639 ChemDiv1_007872 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F19 compound treatment 276.5 89.4 0.47 297.5 96.2 0.5 0.6833 0.9994 1974019 ChemDiv1_007873 CC1CCCN(C1)C(=O)c2sc3nc(C)nc(N4CCN(C)CC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F20 compound treatment 282.6 95.5 0.5 304.3 103.0 0.54 0.7308 0.9994 1308157 ChemDiv1_007874 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F21 compound treatment 278.2 91.1 0.48 299.0 97.7 0.51 0.6951 0.9995 1787046 ChemDiv1_007875 OC(=O)C1CCCN1c2nc(c3ccccc3)c4cc(ccc4n2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F22 compound treatment 275.3 88.2 0.46 300.6 99.3 0.52 0.6903 0.9984 1704053 ChemDiv1_007876 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4ccc(C)cc4nc3Cl)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F23 mock treatment 279.5 92.4 0.48 297.2 95.9 0.5 0.6933 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 F24 mock treatment 76.4 -111.0 -0.58 91.1 -110.0 -0.57 -0.8134 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G01 compound treatment 287.0 99.9 0.52 310.5 109.0 0.57 0.7698 0.9991 1215849 ChemDiv1_007877 COc1ccc(cc1OC)c2nc(NCc3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G02 compound treatment 279.3 92.2 0.48 306.4 105.0 0.55 0.7264 0.998 1205912 ChemDiv1_007878 CCC(C)NC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G03 compound treatment 280.0 92.9 0.48 304.7 103.0 0.54 0.7227 0.9987 1621556 ChemDiv1_007879 Cc1sc2nc(C)nc(NC3CCN(Cc4ccccc4)CC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G04 compound treatment 274.7 87.6 0.46 300.2 98.9 0.51 0.6866 0.9983 1253066 ChemDiv1_007880 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCC(C)CC5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G05 compound treatment 280.9 93.8 0.49 304.2 103.0 0.53 0.7242 0.999 1691123 ChemDiv1_007881 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G06 compound treatment 276.9 89.8 0.47 301.5 100.0 0.52 0.6995 0.9986 1613944 ChemDiv1_007882 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCC5CCCO5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G07 compound treatment 275.7 88.6 0.46 301.5 100.0 0.52 0.6951 0.9982 1418585 ChemDiv1_007883 CCOC(=O)N1CCN(CC1)c2nc(nc3ccccc23)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G08 compound treatment 279.5 92.4 0.48 297.6 96.3 0.5 0.6948 0.9998 1450370 ChemDiv1_007884 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCC6(CC5)OCCO6)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G09 compound treatment 279.7 92.6 0.48 306.5 105.0 0.55 0.7282 0.9981 1592211 ChemDiv1_007885 CC1CCCN(C1)C(=O)Cn2cnc3sc(C(=O)Nc4c(C)cc(Br)cc4C)c(C)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G10 compound treatment 280.7 93.6 0.49 303.6 102.0 0.53 0.7212 0.9991 1277241 ChemDiv1_007886 CCN1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G11 compound treatment 279.6 92.5 0.48 302.4 101.0 0.53 0.7128 0.9991 1241523 ChemDiv1_007887 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CC(C)CC(C)C3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G12 compound treatment 280.8 93.7 0.49 302.5 101.0 0.53 0.7176 0.9993 1974020 ChemDiv1_007888 COc1ccc(cc1NC(=O)c2sc3ncnc(N4CCCCC4)c3c2C)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G13 compound treatment 275.5 88.4 0.46 300.4 99.1 0.52 0.6903 0.9985 1430401 ChemDiv1_007889 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(Cc5ccccc5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G14 compound treatment 283.1 96.0 0.5 306.6 105.0 0.55 0.7411 0.999 1321254 ChemDiv1_007890 Cc1c(sc2ncnc(N3CCCCC3)c12)C(=O)N4CCN(CC4)c5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G15 compound treatment 275.0 87.9 0.46 295.1 93.8 0.49 0.669 0.9995 1459968 ChemDiv1_007891 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G16 compound treatment 274.8 87.7 0.46 302.0 101.0 0.52 0.6936 0.9977 1339394 ChemDiv1_007892 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G17 compound treatment 273.1 86.0 0.45 298.7 97.4 0.51 0.6752 0.9982 1557599 ChemDiv1_007893 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G18 compound treatment 275.9 88.8 0.46 298.4 97.1 0.5 0.6844 0.9991 1640539 ChemDiv1_007894 CN1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G19 compound treatment 278.2 91.1 0.48 299.9 98.6 0.51 0.6984 0.9993 1431695 ChemDiv1_007895 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)NCC4COc5ccccc5O4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G20 compound treatment 277.9 90.8 0.47 296.0 94.7 0.49 0.683 0.9998 1137909 ChemDiv1_007896 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G21 compound treatment 275.2 88.1 0.46 297.9 96.6 0.5 0.68 0.999 1411056 ChemDiv1_007897 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G22 compound treatment 274.0 86.9 0.45 294.6 93.3 0.48 0.6635 0.9994 1428083 ChemDiv1_007898 CC1CCCCN1C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G23 mock treatment 279.7 92.6 0.48 293.2 91.9 0.48 0.6793 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 G24 mock treatment 78.6 -109.0 -0.57 92.6 -109.0 -0.57 -0.7998 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H01 compound treatment 285.4 98.3 0.51 311.0 110.0 0.57 0.7658 0.9986 1339200 ChemDiv1_007899 CCOc1ccccc1NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H02 compound treatment 283.2 96.1 0.5 310.7 109.0 0.57 0.7566 0.998 1974021 ChemDiv1_007900 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H03 compound treatment 278.9 91.8 0.48 305.9 105.0 0.54 0.7231 0.998 1974022 ChemDiv1_007901 COc1ccc(cc1NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H04 compound treatment 278.7 91.6 0.48 309.1 108.0 0.56 0.7341 0.9969 1974023 ChemDiv1_007902 CCOc1ccc(/N=C/2\NC(=O)\C(=C\3/C(=O)Nc4ccc(Br)cc34)\S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H05 compound treatment 281.6 94.5 0.49 301.8 100.0 0.52 0.718 0.9996 1387828 ChemDiv1_007903 CCN(CC)CCNc1nc(nc2ccccc12)c3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H06 compound treatment 277.9 90.8 0.47 304.5 103.0 0.54 0.7142 0.9981 1392980 ChemDiv1_007904 CCOc1ccc2nc(SCCC(=O)Nc3ccc(OC)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H07 compound treatment 281.5 94.4 0.49 300.9 99.6 0.52 0.7143 0.9997 1974024 ChemDiv1_007905 CCOC(=O)C1CCCN(C1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H08 compound treatment 279.7 92.6 0.48 301.5 100.0 0.52 0.7098 0.9993 1974025 ChemDiv1_007906 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)N3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H09 compound treatment 271.9 84.8 0.44 304.7 103.0 0.54 0.6928 0.9953 1974026 ChemDiv1_007907 CN1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCC(Cc5ccccc5)CC4)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H10 compound treatment 279.8 92.7 0.48 303.0 102.0 0.53 0.7157 0.999 1579724 ChemDiv1_007908 Cc1ccc(NC(=O)CC2SC(=O)N(CN3CCOCC3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H11 compound treatment 276.4 89.3 0.47 299.1 97.8 0.51 0.6888 0.999 1974027 ChemDiv1_007909 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCC(=O)N4CCN(CC4)c5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H12 compound treatment 275.4 88.3 0.46 299.1 97.8 0.51 0.6852 0.9988 1468348 ChemDiv1_007910 C=CCn1c(SCC(=O)NCCN2CCOCC2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H13 compound treatment 275.5 88.4 0.46 301.8 100.0 0.52 0.6955 0.9981 1974028 ChemDiv1_007911 Fc1ccc(cc1)N2CCN(CC2)C(=O)CNC(=O)Cn3cnc4sc5CCCCc5c4c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H14 compound treatment 273.8 86.7 0.45 301.0 99.7 0.52 0.6862 0.9977 1974029 ChemDiv1_007912 OC(=O)CCC(=O)N1N=C(CC1c2ccccn2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H15 compound treatment 275.3 88.2 0.46 298.8 97.5 0.51 0.6837 0.9988 1974030 ChemDiv1_007913 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3ccccc3F)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H16 compound treatment 278.4 91.3 0.48 299.3 98.0 0.51 0.697 0.9994 1258712 ChemDiv1_007914 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H17 compound treatment 275.8 88.7 0.46 302.1 101.0 0.52 0.6977 0.9981 1974031 ChemDiv1_007915 CCN(C(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)c3cc(OC)ccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H18 compound treatment 282.0 94.9 0.5 304.5 103.0 0.54 0.7294 0.9992 1227360 ChemDiv1_007916 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H19 compound treatment 274.1 87.0 0.45 300.1 98.8 0.51 0.684 0.9981 1974032 ChemDiv1_007917 COc1ccc(Cl)cc1N(C)C(=O)CCNC(=O)Cn2cnc3ccccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H20 compound treatment 280.2 93.1 0.49 306.6 105.0 0.55 0.7304 0.9982 1974033 ChemDiv1_007918 COc1ccc(cc1OC)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H21 compound treatment 276.5 89.4 0.47 294.2 92.9 0.48 0.6712 0.9998 1153036 ChemDiv1_007919 OC(=O)CC1(CC(=O)N2CCN(CC2)c3nc(c4ccccc4)c5ccccc5n3)CCCC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H22 compound treatment 277.0 89.9 0.47 296.8 95.5 0.5 0.6826 0.9996 1283533 ChemDiv1_007920 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4cc(C)ccc4nc3Cl)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H23 mock treatment 279.4 92.3 0.48 298.8 97.5 0.51 0.6988 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 H24 mock treatment 75.8 -111.0 -0.58 90.4 -111.0 -0.58 -0.8182 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I01 compound treatment 287.0 99.9 0.52 312.3 111.0 0.58 0.7765 0.9987 1282612 ChemDiv1_007921 COc1ccc(cc1OC)c2nc(NC3CCCCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I02 compound treatment 279.9 92.8 0.48 304.2 103.0 0.53 0.7205 0.9988 1656125 ChemDiv1_007922 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncnc(N4CCOCC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I03 compound treatment 279.7 92.6 0.48 308.8 107.0 0.56 0.7367 0.9974 1165995 ChemDiv1_007923 COc1ccc(CCNc2nc(C)nc3sc(C)c(C)c23)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I04 compound treatment 279.7 92.6 0.48 306.9 106.0 0.55 0.7297 0.998 1974034 ChemDiv1_007924 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCCCN5CCOCC5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I05 compound treatment 276.9 89.8 0.47 306.0 105.0 0.54 0.7161 0.9972 1639480 ChemDiv1_007925 CN(C)CCNc1nc(Cc2ccccc2)nc3sc4CCCCc4c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I06 compound treatment 277.5 90.4 0.47 305.6 104.0 0.54 0.7168 0.9976 1148725 ChemDiv1_007926 CCN1CCCC1CNC(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I07 compound treatment 278.8 91.7 0.48 304.8 103.0 0.54 0.7187 0.9983 1342021 ChemDiv1_007927 Cc1ccc(cc1)c2nc(N3CCC(CC3)C(=O)N)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I08 compound treatment 278.5 91.4 0.48 306.4 105.0 0.55 0.7234 0.9977 1974035 ChemDiv1_007928 CCOC(CNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I09 compound treatment 277.5 90.4 0.47 304.7 103.0 0.54 0.7135 0.9979 1231281 ChemDiv1_007929 CCOC(=O)c1nc(Nc2cccc(NC(=O)C)c2)c3ccccc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I10 compound treatment 275.0 87.9 0.46 302.7 101.0 0.53 0.6969 0.9976 1974036 ChemDiv1_007930 CCN(CC)CCCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I11 compound treatment 272.9 85.8 0.45 300.4 99.1 0.52 0.6807 0.9975 1245088 ChemDiv1_007931 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccc(F)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I12 compound treatment 276.1 89.0 0.46 299.7 98.4 0.51 0.6899 0.9988 1430619 ChemDiv1_007932 CCN(C(=O)c1sc2nc(C)nc(N3CCCCC3)c2c1C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I13 compound treatment 277.6 90.5 0.47 298.8 97.5 0.51 0.6922 0.9994 1376432 ChemDiv1_007933 CC1CC(C)CN(C1)C(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I14 compound treatment 281.5 94.4 0.49 299.8 98.5 0.51 0.7102 0.9998 1636390 ChemDiv1_007934 Cc1c(sc2ncn(CC(=O)N3CCOCC3)c(=O)c12)C(=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I15 compound treatment 275.3 88.2 0.46 299.7 98.4 0.51 0.687 0.9986 1706317 ChemDiv1_007935 CCOC(=O)c1ccccc1NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I16 compound treatment 277.6 90.5 0.47 300.5 99.2 0.52 0.6984 0.999 1607845 ChemDiv1_007936 CN(Cc1ccccc1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I17 compound treatment 276.0 88.9 0.46 297.8 96.5 0.5 0.6826 0.9992 1641962 ChemDiv1_007937 CCOC(CNc1nc(nc2sc3CCCCc3c12)C(=O)OCC)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I18 compound treatment 275.4 88.3 0.46 301.2 99.9 0.52 0.6929 0.9982 1714854 ChemDiv1_007938 COc1ccc(OC)c(NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I19 compound treatment 276.9 89.8 0.47 302.7 101.0 0.53 0.7039 0.9983 1158840 ChemDiv1_007939 CCOC(=O)C1CCCN(C1)c2nc(nc3sc4CCCCc4c23)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I20 compound treatment 274.7 87.6 0.46 299.7 98.4 0.51 0.6848 0.9984 1349272 ChemDiv1_007940 CCCN(CCC)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I21 compound treatment 274.9 87.8 0.46 300.8 99.5 0.52 0.6896 0.9982 1399150 ChemDiv1_007941 CCN(CC)C(=O)Cn1cnc2sc(C(=O)Nc3c(F)cc(F)cc3Br)c(C)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I22 compound treatment 272.3 85.2 0.44 296.4 95.1 0.49 0.6638 0.9986 1136979 ChemDiv1_007942 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(Cc6ccccc6)CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I23 mock treatment 279.5 92.4 0.48 296.2 94.9 0.49 0.6896 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 I24 mock treatment 77.7 -109.0 -0.57 90.0 -111.0 -0.58 -0.8127 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J01 compound treatment 284.4 97.3 0.51 306.6 105.0 0.55 0.7459 0.9993 1636890 ChemDiv1_007943 CN1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J02 compound treatment 281.3 94.2 0.49 308.9 108.0 0.56 0.7429 0.9979 1520547 ChemDiv1_007944 CC(=O)N1CCN(CC1)c2nc(c3ccccc3Cl)c4cc(Br)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J03 compound treatment 280.8 93.7 0.49 304.1 103.0 0.53 0.7235 0.999 1974037 ChemDiv1_007945 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(Cc6ccc7OCOc7c6)CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J04 compound treatment 282.2 95.1 0.5 305.7 104.0 0.54 0.7345 0.999 1941792 ChemDiv1_007946 COc1ccc(cc1)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J05 compound treatment 281.5 94.4 0.49 307.3 106.0 0.55 0.7378 0.9984 1145694 ChemDiv1_007947 Fc1ccccc1c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J06 compound treatment 279.9 92.8 0.48 302.7 101.0 0.53 0.715 0.9991 1260944 ChemDiv1_007948 CC(=O)Nc1cccc(NC(=O)CSc2nc3ccccc3o2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J07 compound treatment 279.5 92.4 0.48 304.9 104.0 0.54 0.7216 0.9985 1974038 ChemDiv1_007949 CCN1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J08 compound treatment 276.9 89.8 0.47 304.2 103.0 0.53 0.7094 0.9978 1484828 ChemDiv1_007950 Cc1cc(NC(=O)CSc2ncn[nH]2)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J09 compound treatment 278.3 91.2 0.48 299.7 98.4 0.51 0.6981 0.9993 1974039 ChemDiv1_007951 CC1CCCCN1c2ncnc3sc(C(=O)N4CCC(CC4)(N5CCCCC5)C(=O)N)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J10 compound treatment 282.7 95.6 0.5 300.2 98.9 0.51 0.7161 0.9999 1974040 ChemDiv1_007952 CCCCOC(=O)Nc1nc(C)c(s1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J11 compound treatment 275.5 88.4 0.46 302.7 101.0 0.53 0.6988 0.9978 1974041 ChemDiv1_007953 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCC(=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J12 compound treatment 275.0 87.9 0.46 301.3 100.0 0.52 0.6918 0.998 1466714 ChemDiv1_007954 Cc1sc2nc(SCC(=O)NCCN3CCOCC3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J13 compound treatment 278.4 91.3 0.48 303.3 102.0 0.53 0.7117 0.9986 1974042 ChemDiv1_007955 CCn1c(C(=O)O)c(CC(=O)Nc2nc3ccc(OC)cc3s2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J14 compound treatment 275.9 88.8 0.46 296.9 95.6 0.5 0.6789 0.9994 1974043 ChemDiv1_007956 OC(=O)CCCC(=O)N1N=C(CC1c2ccccn2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J15 compound treatment 273.8 86.7 0.45 300.8 99.5 0.52 0.6855 0.9978 1974044 ChemDiv1_007957 CCn1c(C(=O)O)c(CC(=O)NCCc2ccc(OC)c(OC)c2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J16 compound treatment 278.4 91.3 0.48 301.7 100.0 0.52 0.7058 0.999 1621889 ChemDiv1_007958 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J17 compound treatment 277.1 90.0 0.47 302.6 101.0 0.53 0.7043 0.9984 1974045 ChemDiv1_007959 CCN(C(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)c3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J18 compound treatment 284.8 97.7 0.51 307.9 107.0 0.55 0.7522 0.9991 1436300 ChemDiv1_007960 COc1ccc(OC)c(c1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J19 compound treatment 270.9 83.8 0.44 299.1 97.8 0.51 0.6686 0.9972 1472083 ChemDiv1_007961 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J20 compound treatment 280.5 93.4 0.49 303.0 102.0 0.53 0.7183 0.9992 1974046 ChemDiv1_007962 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(cc3)N(C)C)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J21 compound treatment 274.4 87.3 0.46 295.0 93.7 0.49 0.6664 0.9994 1688559 ChemDiv1_007963 CC(C)(C)OC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J22 compound treatment 278.2 91.1 0.48 296.7 95.4 0.5 0.6867 0.9998 1659414 ChemDiv1_007964 COc1ccc(cc1OC)C2=NN(C(C2)c3cn(nc3c4ccccc4)c5ccccc5)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J23 mock treatment 277.2 90.1 0.47 297.6 96.3 0.5 0.6863 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 J24 mock treatment 76.6 -111.0 -0.58 95.2 -106.0 -0.55 -0.7976 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K01 compound treatment 286.7 99.6 0.52 310.4 109.0 0.57 0.7684 0.999 1730022 ChemDiv1_007965 COc1cc(cc(OC)c1OC)c2nc(NCc3ccc(F)cc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K02 compound treatment 278.7 91.6 0.48 305.4 104.0 0.54 0.7205 0.9981 1358960 ChemDiv1_007966 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(Cc5ccccc5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K03 compound treatment 288.7 102.0 0.53 303.9 103.0 0.53 0.7519 1.0 1541557 ChemDiv1_007967 COc1ccccc1N2CCN(CC2)c3ncnc4sc5CCCCc5c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K04 compound treatment 279.5 92.4 0.48 305.4 104.0 0.54 0.7234 0.9983 1439265 ChemDiv1_007968 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCc5ccco5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K05 compound treatment 280.0 92.9 0.48 305.6 104.0 0.54 0.726 0.9984 1657534 ChemDiv1_007969 C(Nc1nc(Cc2ccccc2)nc3sc4CCCCc4c13)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K06 compound treatment 280.2 93.1 0.49 304.0 103.0 0.53 0.7209 0.9989 1974047 ChemDiv1_007970 CCN(CC)CCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K07 compound treatment 276.0 88.9 0.46 300.4 99.1 0.52 0.6922 0.9986 1545022 ChemDiv1_007971 Cc1ccc(cc1)c2nc(N3CCC4(CC3)OCCO4)c5ccccc5n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K08 compound treatment 275.8 88.7 0.46 303.2 102.0 0.53 0.7017 0.9977 1517188 ChemDiv1_007972 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCc5ccccn5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K09 compound treatment 279.0 91.9 0.48 300.0 98.7 0.51 0.7017 0.9994 1267848 ChemDiv1_007973 CCOC(=O)c1sc2ncnc(NCC3COc4ccccc4O3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K10 compound treatment 276.6 89.5 0.47 299.9 98.6 0.51 0.6925 0.9989 1272901 ChemDiv1_007974 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K11 compound treatment 276.4 89.3 0.47 302.0 101.0 0.52 0.6995 0.9983 1124849 ChemDiv1_007975 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K12 compound treatment 275.4 88.3 0.46 303.1 102.0 0.53 0.6999 0.9976 1658386 ChemDiv1_007976 CCCN(CCC)C(=O)c1sc2nc(C)nc(N3CCCCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K13 compound treatment 275.8 88.7 0.46 299.0 97.7 0.51 0.6863 0.9989 1591775 ChemDiv1_007977 COc1ccc(C)cc1NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K14 compound treatment 275.0 87.9 0.46 301.2 99.9 0.52 0.6914 0.9981 1739002 ChemDiv1_007978 Cc1sc2ncn(CC(=O)NCC(=O)N3CCN(CC3)c4ccc(F)cc4)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K15 compound treatment 273.6 86.5 0.45 300.8 99.5 0.52 0.6848 0.9977 1264092 ChemDiv1_007979 CCOc1ccccc1NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K16 compound treatment 279.1 92.0 0.48 300.1 98.8 0.51 0.7025 0.9994 1688609 ChemDiv1_007980 CC1CCCCN1C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K17 compound treatment 280.4 93.3 0.49 301.5 100.0 0.52 0.7124 0.9994 1308514 ChemDiv1_007981 CCOC(=O)c1nc(N2CCN(CC2)c3ccccn3)c4c5CCCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K18 compound treatment 275.9 88.8 0.46 296.4 95.1 0.49 0.6771 0.9995 1416045 ChemDiv1_007982 CCCCN(CC)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K19 compound treatment 279.4 92.3 0.48 298.7 97.4 0.51 0.6984 0.9997 1719962 ChemDiv1_007983 CCOC(=O)c1nc(NCc2cccnc2)c3c4CCCCc4sc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K20 compound treatment 274.5 87.4 0.46 300.7 99.4 0.52 0.6877 0.9981 1482905 ChemDiv1_007984 CCOc1ccc(NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K21 compound treatment 280.9 93.8 0.49 299.4 98.1 0.51 0.7065 0.9998 1341822 ChemDiv1_007985 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K22 compound treatment 277.9 90.8 0.47 296.3 95.0 0.49 0.6841 0.9998 1435905 ChemDiv1_007986 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(Cc6ccccc6)CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K23 mock treatment 279.8 92.7 0.48 295.7 94.4 0.49 0.6889 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 K24 mock treatment 78.3 -109.0 -0.57 90.0 -111.0 -0.58 -0.8104 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L01 compound treatment 283.3 96.2 0.5 308.1 107.0 0.56 0.7474 0.9987 1474666 ChemDiv1_007987 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L02 compound treatment 281.6 94.5 0.49 304.6 103.0 0.54 0.7282 0.9991 1098309 ChemDiv1_007988 CC1(C)NC(Cc2c1[nH]c3ccccc23)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L03 compound treatment 277.3 90.2 0.47 305.1 104.0 0.54 0.7142 0.9977 1198760 ChemDiv1_007989 CCN(CC)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L04 compound treatment 278.9 91.8 0.48 305.4 104.0 0.54 0.7212 0.9981 1941751 ChemDiv1_007990 COc1ccc(cc1OC)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L05 compound treatment 280.3 93.2 0.49 304.1 103.0 0.53 0.7216 0.9989 1190790 ChemDiv1_007991 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4)c12)C(=O)N5CCC(CC5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L06 compound treatment 281.1 94.0 0.49 302.2 101.0 0.52 0.7176 0.9994 1705476 ChemDiv1_007992 COc1ccc2[nH]c(SCC(=O)Nc3cccc(NC(=O)C)c3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L07 compound treatment 278.2 91.1 0.48 303.1 102.0 0.53 0.7102 0.9986 1974048 ChemDiv1_007993 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4F)c12)C(=O)N5CCC(CC5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L08 compound treatment 279.6 92.5 0.48 302.8 101.0 0.53 0.7143 0.999 1974049 ChemDiv1_007994 Cc1cc(NC(=O)CSc2nnc(C)[nH]2)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L09 compound treatment 274.5 87.4 0.46 302.9 102.0 0.53 0.6958 0.9973 1974050 ChemDiv1_007995 COc1ccc(OC)c(NC(=O)c2sc3ncnc(N4CCCCC4C)c3c2C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L10 compound treatment 278.8 91.7 0.48 304.3 103.0 0.54 0.7168 0.9984 1974051 ChemDiv1_007996 CCCCOC(=O)Nc1nc2ccccc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L11 compound treatment 277.0 89.9 0.47 303.7 102.0 0.53 0.708 0.998 1974052 ChemDiv1_007997 CCN(CCCNC(=O)c1sc2ncn(CC(=O)N3CCCCC3C)c(=O)c2c1C)Cc4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L12 compound treatment 279.2 92.1 0.48 309.0 108.0 0.56 0.7356 0.9971 1929155 ChemDiv1_007998 CN1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3cccs3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L13 compound treatment 277.8 90.7 0.47 297.8 96.5 0.5 0.6892 0.9996 1974053 ChemDiv1_007999 CCn1c(C(=O)O)c(CC(=O)Nc2ccc(C)cc2Br)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L14 compound treatment 276.6 89.5 0.47 298.5 97.2 0.51 0.6874 0.9992 1974054 ChemDiv1_008000 CCOc1ccc2cc(C3=NN(C(C3)c4ccc(Br)cc4)C(=O)CCC(=O)O)c(Cl)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L15 compound treatment 275.6 88.5 0.46 301.6 100.0 0.52 0.6951 0.9982 1974055 ChemDiv1_008001 CCn1c(C(=O)O)c(CC(=O)N2CCN(Cc3ccccc3)CC2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L16 compound treatment 277.3 90.2 0.47 297.7 96.4 0.5 0.687 0.9995 1686855 ChemDiv1_008002 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L17 compound treatment 274.4 87.3 0.46 301.0 99.7 0.52 0.6885 0.9979 1974056 ChemDiv1_008003 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3ccc(OC)cc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L18 compound treatment 276.3 89.2 0.47 297.1 95.8 0.5 0.6811 0.9994 1225785 ChemDiv1_008004 COc1ccc(OC)c(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L19 compound treatment 278.9 91.8 0.48 295.6 94.3 0.49 0.6852 0.9999 1256020 ChemDiv1_008005 CCOC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(C)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L20 compound treatment 286.5 99.4 0.52 320.2 119.0 0.62 0.8037 0.9962 1974057 ChemDiv1_008006 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L21 compound treatment 277.6 90.5 0.47 296.6 95.3 0.5 0.6841 0.9997 1302214 ChemDiv1_008007 O=C(N1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L22 compound treatment 276.2 89.1 0.46 299.2 97.9 0.51 0.6885 0.999 1385918 ChemDiv1_008008 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)C)c4cccs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L23 mock treatment 279.0 91.9 0.48 294.8 93.5 0.49 0.6826 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 L24 mock treatment 80.1 -107.0 -0.56 91.4 -110.0 -0.57 -0.7987 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M01 compound treatment 281.0 93.9 0.49 310.5 109.0 0.57 0.7477 0.9973 1334305 ChemDiv1_008009 CCOC(=O)C1CCN(CC1)c2nc(nc3ccccc23)c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M02 compound treatment 282.9 95.8 0.5 305.4 104.0 0.54 0.736 0.9992 1355735 ChemDiv1_008010 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCCC5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M03 compound treatment 280.7 93.6 0.49 305.2 104.0 0.54 0.7271 0.9987 1707349 ChemDiv1_008011 COc1ccc(CCNc2ncnc3scc(c4ccccc4)c23)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M04 compound treatment 276.5 89.4 0.47 302.7 101.0 0.53 0.7024 0.9981 1974058 ChemDiv1_008012 CCCCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M05 compound treatment 278.2 91.1 0.48 305.4 104.0 0.54 0.7186 0.9979 1420071 ChemDiv1_008013 C(Nc1nc(Cc2ccccc2)nc3sc4CCCCc4c13)C5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M06 compound treatment 279.1 92.0 0.48 301.1 99.8 0.52 0.7062 0.9992 1974059 ChemDiv1_008014 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCC(CC5)(N6CCCCC6)C(=O)N)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M07 compound treatment 274.5 87.4 0.46 304.5 103.0 0.54 0.7017 0.9967 1186451 ChemDiv1_008015 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M08 compound treatment 278.9 91.8 0.48 305.5 104.0 0.54 0.7216 0.9981 1145236 ChemDiv1_008016 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCN(CC5)c6ccccn6)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M09 compound treatment 281.2 94.1 0.49 300.4 99.1 0.52 0.7113 0.9997 1974060 ChemDiv1_008017 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M10 compound treatment 278.1 91.0 0.47 300.3 99.0 0.51 0.6995 0.9992 1700128 ChemDiv1_008018 CCOC(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M11 compound treatment 277.1 90.0 0.47 301.7 100.0 0.52 0.701 0.9986 1592881 ChemDiv1_008019 CCOC(=O)c1sc2nc(CC(=O)OC)nc(NCCN3CCOCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M12 compound treatment 275.3 88.2 0.46 301.3 100.0 0.52 0.6929 0.9982 1495135 ChemDiv1_008020 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M13 compound treatment 277.4 90.3 0.47 304.4 103.0 0.54 0.712 0.9979 1296438 ChemDiv1_008021 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M14 compound treatment 276.6 89.5 0.47 299.2 97.9 0.51 0.69 0.9991 1454500 ChemDiv1_008022 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4F)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M15 compound treatment 275.8 88.7 0.46 302.9 102.0 0.53 0.7006 0.9978 1156342 ChemDiv1_008023 COc1ccc(cc1)N2CCN(CC2)C(=O)c3sc4nc(C)nc(N5CCOCC5)c4c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M16 compound treatment 277.6 90.5 0.47 300.1 98.8 0.51 0.6969 0.9991 1606226 ChemDiv1_008024 Cc1c(sc2ncnc(N3CCc4ccccc4C3)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M17 compound treatment 278.6 91.5 0.48 293.7 92.4 0.48 0.6771 1.0 1542467 ChemDiv1_008025 CCOC(=O)c1nc(Nc2ccc3OCOc3c2)c4c5CCCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M18 compound treatment 281.9 94.8 0.49 299.7 98.4 0.51 0.7113 0.9999 1388209 ChemDiv1_008026 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)Nc5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M19 compound treatment 273.7 86.6 0.45 297.3 96.0 0.5 0.6723 0.9988 1319850 ChemDiv1_008027 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)Nc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M20 compound treatment 275.6 88.5 0.46 295.4 94.1 0.49 0.6723 0.9996 1243252 ChemDiv1_008028 CCOC(=O)c1ccccc1NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M21 compound treatment 276.9 89.8 0.47 294.0 92.7 0.48 0.6719 0.9999 1522039 ChemDiv1_008029 CN(C)c1ccc(CN(Cc2ccco2)C(=O)c3sc4nc(C)nc(N5CCOCC5)c4c3C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M22 compound treatment 282.8 95.7 0.5 297.1 95.8 0.5 0.7051 1.0 1337979 ChemDiv1_008030 CCCCN(C)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M23 mock treatment 279.9 92.8 0.48 294.2 92.9 0.48 0.6837 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 M24 mock treatment 196.6 9.5 0.05 200.6 -0.706 0.0 0.0324 0.6529 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N01 compound treatment 280.8 93.7 0.49 309.2 108.0 0.56 0.7422 0.9977 1441255 ChemDiv1_008031 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC6(CC5)OCCO6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N02 compound treatment 281.2 94.1 0.49 304.1 103.0 0.53 0.7249 0.9991 1974061 ChemDiv1_008032 COc1ccc(/C=C/2\SC(=O)N(CC(=O)Nc3cccc(O)c3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N03 compound treatment 282.5 95.4 0.5 308.5 107.0 0.56 0.7459 0.9984 1538226 ChemDiv1_008033 CN1CCN(CC1)c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N04 compound treatment 282.4 95.3 0.5 306.1 105.0 0.54 0.7367 0.999 1927729 ChemDiv1_008034 COc1cc(ccc1O)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N05 compound treatment 277.9 90.8 0.47 303.9 103.0 0.53 0.712 0.9983 1583798 ChemDiv1_008035 C1CN(CCC1N2CCCCCC2)c3ncnc4scc(c5ccccc5)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N06 compound treatment 281.5 94.4 0.49 307.7 106.0 0.55 0.7393 0.9983 1974062 ChemDiv1_008036 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)NC3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N07 compound treatment 282.7 95.6 0.5 299.7 98.4 0.51 0.7143 0.9999 1974063 ChemDiv1_008037 Cc1c(sc2ncnc(N3CCc4ccccc4C3)c12)C(=O)N5CCC(CC5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N08 compound treatment 277.4 90.3 0.47 305.1 104.0 0.54 0.7146 0.9977 1974064 ChemDiv1_008038 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2cc(C)on2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N09 compound treatment 279.1 92.0 0.48 300.5 99.2 0.52 0.704 0.9994 1974065 ChemDiv1_008039 CC1CCCCN1c2ncnc3sc(C(=O)Nc4ccc5OCOc5c4)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N10 compound treatment 278.0 90.9 0.47 300.7 99.4 0.52 0.7006 0.9991 1219654 ChemDiv1_008040 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CCc3ccccc3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N11 compound treatment 275.5 88.4 0.46 302.1 101.0 0.52 0.6966 0.998 1974066 ChemDiv1_008041 CCN1CCN(CC1)C(=O)CNC(=O)Cn2cnc3SC4CCCCC4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N12 compound treatment 277.0 89.9 0.47 300.5 99.2 0.52 0.6962 0.9989 1382797 ChemDiv1_008042 CCOc1cc(ccc1OCc2ccccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N13 compound treatment 272.9 85.8 0.45 299.9 98.6 0.51 0.6789 0.9977 1974067 ChemDiv1_008043 CCn1c(C(=O)O)c(CC(=O)Nc2ccc(Oc3ccccc3)cc2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N14 compound treatment 276.6 89.5 0.47 302.6 101.0 0.53 0.7024 0.9982 1298974 ChemDiv1_008044 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N15 compound treatment 276.7 89.6 0.47 302.5 101.0 0.53 0.7025 0.9983 1974068 ChemDiv1_008045 CCn1c(C(=O)O)c(CC(=O)N2CCC(CC2)(N3CCCCC3)C(=O)N)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N16 compound treatment 276.7 89.6 0.47 298.2 96.9 0.5 0.6866 0.9993 1153035 ChemDiv1_008046 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N17 compound treatment 276.8 89.7 0.47 302.0 101.0 0.52 0.701 0.9984 1974069 ChemDiv1_008047 CCn1c(C(=O)O)c(CC(=O)N(C)c2cc(Cl)c(OC)cc2OC)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N18 compound treatment 283.8 96.7 0.5 310.8 109.0 0.57 0.7591 0.9982 1552712 ChemDiv1_008048 COc1ccc(cc1OC)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N19 compound treatment 278.6 91.5 0.48 300.5 99.2 0.52 0.7021 0.9993 1974070 ChemDiv1_008049 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N20 compound treatment 278.6 91.5 0.48 296.9 95.6 0.5 0.6889 0.9998 1974071 ChemDiv1_008050 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N21 compound treatment 274.5 87.4 0.46 295.3 94.0 0.49 0.6679 0.9994 1431392 ChemDiv1_008051 CCOC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N22 compound treatment 280.6 93.5 0.49 294.8 93.5 0.49 0.6885 1.0 1974072 ChemDiv1_008052 COc1cc(cc(OC)c1OC)c2nc(Cl)nc3ccc(Cl)cc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N23 mock treatment 281.5 94.4 0.49 296.5 95.2 0.49 0.6981 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 N24 mock treatment 195.0 7.9 0.04 204.5 3.19 0.02 0.0409 0.9201 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O01 compound treatment 284.1 97.0 0.51 307.4 106.0 0.55 0.7478 0.9991 1974073 ChemDiv1_008053 Cc1ccc(cc1)c2nc(NCc3cccs3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O02 compound treatment 284.1 97.0 0.51 309.4 108.0 0.56 0.7551 0.9986 1974074 ChemDiv1_008054 COCCCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O03 compound treatment 279.8 92.7 0.48 303.2 102.0 0.53 0.7165 0.999 1974075 ChemDiv1_008055 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)c3ncnc4sc5CCCCc5c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O04 compound treatment 281.6 94.5 0.49 306.4 105.0 0.55 0.7349 0.9987 1705377 ChemDiv1_008056 CCOC(=O)C1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O05 compound treatment 280.7 93.6 0.49 304.8 103.0 0.54 0.7257 0.9988 1212922 ChemDiv1_008057 CCOC(=O)c1sc2nc(Cc3ccccc3)nc(NCC4CCCO4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O06 compound treatment 276.6 89.5 0.47 302.8 101.0 0.53 0.7032 0.9981 1696292 ChemDiv1_008058 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCc5cccnc5)c(C)c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O07 compound treatment 277.5 90.4 0.47 299.4 98.1 0.51 0.694 0.9992 1668837 ChemDiv1_008059 COC(=O)Cc1nc(N2CCN(CC2)c3ccc(F)cc3)c4c(C)c(C)sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O08 compound treatment 278.8 91.7 0.48 301.9 101.0 0.52 0.708 0.999 1974076 ChemDiv1_008060 COc1cc(Cl)c(C)cc1NC(=O)c2sc3ncn(CC(=O)Nc4cccc(c4)C(F)(F)F)c(=O)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O09 compound treatment 278.5 91.4 0.48 300.4 99.1 0.52 0.7014 0.9993 1137907 ChemDiv1_008061 CCOC(CNc1nc(CC(=O)OC)nc2sc(C(=O)OCC)c(C)c12)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O10 compound treatment 281.7 94.6 0.49 304.1 103.0 0.53 0.7268 0.9992 1158602 ChemDiv1_008062 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O11 compound treatment 278.0 90.9 0.47 302.0 101.0 0.52 0.7054 0.9988 1181323 ChemDiv1_008063 CCOC(=O)c1sc2nc(CC(=O)OC)nc(NCc3cccnc3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O12 compound treatment 277.8 90.7 0.47 295.1 93.8 0.49 0.6793 0.9999 1399136 ChemDiv1_008064 COc1ccccc1N2CCN(CC2)C(=O)c3sc4nc(C)nc(N5CCN(CC5)c6ccccn6)c4c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O13 compound treatment 275.8 88.7 0.46 295.4 94.1 0.49 0.673 0.9996 1216335 ChemDiv1_008065 CC1CCCCN1c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O14 compound treatment 277.6 90.5 0.47 303.9 103.0 0.53 0.7109 0.9982 1712415 ChemDiv1_008066 CC(C)c1ccc(cc1)N(C)c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O15 compound treatment 275.4 88.3 0.46 299.6 98.3 0.51 0.687 0.9987 1974077 ChemDiv1_008067 CCOC(=O)CNC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O16 compound treatment 274.7 87.6 0.46 297.0 95.7 0.5 0.6749 0.9991 1647692 ChemDiv1_008068 COc1ccccc1N2CCN(CC2)c3nc(CC(=O)O)nc4sc5CCCCc5c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O17 compound treatment 278.2 91.1 0.48 300.2 98.9 0.51 0.6995 0.9992 1471117 ChemDiv1_008069 CCOC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O18 compound treatment 270.8 83.7 0.44 297.1 95.8 0.5 0.6608 0.9979 1360059 ChemDiv1_008070 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC6(CC5)OCCO6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O19 compound treatment 277.8 90.7 0.47 300.9 99.6 0.52 0.7006 0.999 1509379 ChemDiv1_008071 CCN(CC)C(=O)Cn1cnc2sc(C(=O)Nc3nc4ccccc4s3)c(C)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O20 compound treatment 277.2 90.1 0.47 296.2 94.9 0.49 0.6811 0.9997 1582645 ChemDiv1_008072 COC(=O)CNC(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O21 compound treatment 279.3 92.2 0.48 294.1 92.8 0.48 0.6812 1.0 1483510 ChemDiv1_008073 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCCC3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O22 compound treatment 277.9 90.8 0.47 295.1 93.8 0.49 0.6797 0.9999 1415491 ChemDiv1_008074 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O23 mock treatment 276.8 89.7 0.47 293.9 92.6 0.48 0.6712 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 O24 mock treatment 95.2 -91.9 -0.48 121.4 -79.9 -0.42 -0.6327 -0.9974 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P01 compound treatment 282.0 94.9 0.5 311.8 110.0 0.57 0.7562 0.9973 1280854 ChemDiv1_008075 CCN1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P02 compound treatment 275.9 88.8 0.46 311.9 111.0 0.57 0.7341 0.9943 1974078 ChemDiv1_008076 COc1ccc(/C=C/2\SC(=O)N(CCCC(=O)N3CCOCC3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P03 compound treatment 281.8 94.7 0.49 310.2 109.0 0.57 0.7496 0.9977 1297433 ChemDiv1_008077 CCOC(=O)c1sc2ncnc(N3CCCCC3C)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P04 compound treatment 286.1 99.0 0.52 308.1 107.0 0.56 0.7577 0.9993 1926655 ChemDiv1_008078 Cc1c(N2C(SCC2=O)c3ccccc3Cl)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P05 compound treatment 282.0 94.9 0.5 306.6 105.0 0.55 0.7371 0.9987 1565563 ChemDiv1_008079 CCCN1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P06 compound treatment 285.5 98.4 0.51 306.8 105.0 0.55 0.7507 0.9995 1974079 ChemDiv1_008080 Cc1ccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P07 compound treatment 286.6 99.5 0.52 303.2 102.0 0.53 0.7415 0.9999 1623167 ChemDiv1_008081 CC1CCCCN1C(=O)Cn2cnc3sc(C(=O)O)c(C)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P08 compound treatment 276.1 89.0 0.46 303.0 102.0 0.53 0.7021 0.9979 1974080 ChemDiv1_008082 Cc1cc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P09 compound treatment 277.8 90.7 0.47 301.0 99.7 0.52 0.701 0.999 1974081 ChemDiv1_008083 CCN(CC)CCCNC(=O)c1sc2ncnc(N3CCCCC3C)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P10 compound treatment 277.7 90.6 0.47 306.0 105.0 0.54 0.719 0.9975 1482356 ChemDiv1_008084 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P11 compound treatment 279.0 91.9 0.48 303.4 102.0 0.53 0.7142 0.9987 1974082 ChemDiv1_008085 CC1CCCCN1c2ncnc3sc(C(=O)N4CCC5(CC4)OCCO5)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P12 compound treatment 275.9 88.8 0.46 300.6 99.3 0.52 0.6925 0.9985 1279826 ChemDiv1_008086 COc1ccc(cc1OCc2ccc(Cl)cc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P13 compound treatment 272.3 85.2 0.44 302.5 101.0 0.53 0.6862 0.9965 1974083 ChemDiv1_008087 CCn1c(C(=O)O)c(CC(=O)Nc2cc(OC)c(OC)c(OC)c2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P14 compound treatment 279.8 92.7 0.48 297.7 96.4 0.5 0.6962 0.9998 1201686 ChemDiv1_008088 COc1ccc(cc1)C2CC(=NN2C(=O)C)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P15 compound treatment 277.3 90.2 0.47 301.5 100.0 0.52 0.701 0.9987 1974084 ChemDiv1_008089 CCn1c(C(=O)O)c(CC(=O)N2CCC(Cc3ccccc3)CC2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P16 compound treatment 280.6 93.5 0.49 298.7 97.4 0.51 0.7029 0.9998 1585727 ChemDiv1_008090 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P17 compound treatment 274.9 87.8 0.46 297.8 96.5 0.5 0.6785 0.999 1974085 ChemDiv1_008091 CCN(CCCNC(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)Cc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P18 compound treatment 282.3 95.2 0.5 303.3 102.0 0.53 0.726 0.9995 1540312 ChemDiv1_008092 COc1ccc(cc1OC)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P19 compound treatment 281.0 93.9 0.49 298.3 97.0 0.5 0.7029 0.9999 1140554 ChemDiv1_008093 OC(=O)C1CCCN1c2nc(c3ccccc3)c4cc(Br)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P20 compound treatment 287.3 100.0 0.52 308.3 107.0 0.56 0.7629 0.9995 1974086 ChemDiv1_008094 COc1ccc(cc1OC)C2CC(=NN2C(=O)c3cc(OC)c(OC)c(OC)c3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P21 compound treatment 281.1 94.0 0.49 296.1 94.8 0.49 0.6952 1.0 1383273 ChemDiv1_008095 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)CC5(CC(=O)O)CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P22 compound treatment 278.0 90.9 0.47 296.7 95.4 0.5 0.6859 0.9998 1974087 ChemDiv1_008096 CC(C)(C)NC(=O)CSc1nc[nH]n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P23 mock treatment 276.3 89.2 0.47 299.9 98.6 0.51 0.6914 0.9988 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.609 P24 mock treatment 95.1 -92.0 -0.48 90.2 -111.0 -0.58 -0.7477 -0.9958 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A01 compound treatment 283.8 96.1 0.5 303.0 109.0 0.57 0.7556 0.9981 1974088 ChemDiv1_008449 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccn3)C(=O)Nc4ccccc4C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A02 compound treatment 285.2 97.5 0.51 295.8 102.0 0.53 0.7343 0.9998 1974089 ChemDiv1_008450 Clc1ccc(Cl)c(NC(=O)CSc2nnc3sc4ccccc4n23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A03 compound treatment 283.4 95.7 0.5 300.9 107.0 0.56 0.7464 0.9985 1544275 ChemDiv1_008451 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc5OCOc5c4)C(=O)Nc6ccccc6F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A04 compound treatment 286.6 98.9 0.52 293.0 99.2 0.52 0.7292 1.0 1477326 ChemDiv1_008452 Cc1ccc(cc1)c2nnc(Oc3ccc(OCc4ccccc4)cc3)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A05 compound treatment 280.3 92.6 0.48 298.2 104.0 0.54 0.725 0.9983 1386052 ChemDiv1_008453 Cc1c(NC(=O)COc2ccc(cc2)C3CCCCC3)cccc1c4nc5ncccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A06 compound treatment 280.0 92.3 0.48 297.2 103.0 0.54 0.7203 0.9985 1540980 ChemDiv1_008454 C=CCn1c(CSc2nc3ccccc3s2)nnc1SCC(=O)NCc4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A07 compound treatment 276.6 88.9 0.46 295.3 101.0 0.53 0.7007 0.9979 1928670 ChemDiv1_008455 COc1ccc(cc1)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A08 compound treatment 276.9 89.2 0.47 298.7 105.0 0.55 0.7143 0.9969 1499095 ChemDiv1_008456 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A09 compound treatment 276.2 88.5 0.46 297.9 104.0 0.54 0.7088 0.9969 1974090 ChemDiv1_008457 OC(=O)COc1ccc(Br)cc1/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A10 compound treatment 275.3 87.6 0.46 294.0 100.0 0.52 0.6912 0.9979 1359187 ChemDiv1_008458 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A11 compound treatment 277.6 89.9 0.47 296.7 103.0 0.53 0.7096 0.9978 1552112 ChemDiv1_008459 C1CCC2(CC1)C3=C(CCCC3)Nc4ncnn42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A12 compound treatment 276.4 88.7 0.46 294.9 101.0 0.53 0.6985 0.998 1974091 ChemDiv1_008460 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A13 compound treatment 279.2 91.5 0.48 293.9 100.0 0.52 0.7052 0.9991 1528870 ChemDiv1_008461 CC1Oc2ccccc2OC1C(=O)NCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A14 compound treatment 275.6 87.9 0.46 294.1 100.0 0.52 0.6926 0.9979 1663296 ChemDiv1_008462 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(cc3)N(C)C)C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A15 compound treatment 275.6 87.9 0.46 297.0 103.0 0.54 0.7033 0.9969 1692728 ChemDiv1_008463 COc1cc(cc(OC)c1OC)C2N(C(=O)CCC(=O)O)c3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A16 compound treatment 279.8 92.1 0.48 299.6 106.0 0.55 0.7283 0.9977 1974092 ChemDiv1_008464 Fc1ccc(cc1)C2CC(=NN2C(=O)c3ccncc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A17 compound treatment 276.8 89.1 0.46 289.8 96.0 0.5 0.6813 0.9994 1974093 ChemDiv1_008465 Nc1nc(Nc2ccc(cc2)[N+](=O)[O-])nc(n1)c3ccc(o3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A18 compound treatment 286.8 99.1 0.52 300.6 107.0 0.56 0.7578 0.9994 1614824 ChemDiv1_008466 COc1ccc(C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A19 compound treatment 275.2 87.5 0.46 287.7 93.9 0.49 0.6676 0.9994 1428667 ChemDiv1_008467 Cc1csc(=Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A20 compound treatment 276.1 88.4 0.46 288.2 94.4 0.49 0.6728 0.9995 1974094 ChemDiv1_008468 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A21 compound treatment 274.3 86.6 0.45 286.7 92.9 0.48 0.6606 0.9994 1974095 ChemDiv1_008469 COC(=O)c1ccc(cc1)n2c(C)cc(C(=O)CSc3nnc4ccccn34)c2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A22 compound treatment 275.2 87.5 0.46 284.1 90.3 0.47 0.6544 0.9999 1974096 ChemDiv1_008470 COc1cc(OC)c(cc1/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(C)c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A23 mock treatment 277.8 90.1 0.47 287.2 93.4 0.49 0.6754 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 A24 mock treatment 72.8 -115.0 -0.6 81.9 -112.0 -0.58 -0.8354 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B01 compound treatment 286.9 99.2 0.52 298.7 105.0 0.55 0.7512 0.9997 1974097 ChemDiv1_008471 CCOC(=O)c1ccc(cc1)c2ccc(/C=C\3/C(=O)NC(=S)N(C3=O)c4ccc(OC)cc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B02 compound treatment 284.8 97.1 0.51 297.6 104.0 0.54 0.7394 0.9995 1974098 ChemDiv1_008472 Nc1nc(SCCBr)c(C#N)c(c1C#N)c2cccc(Cl)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B03 compound treatment 275.5 87.8 0.46 286.6 92.8 0.48 0.6647 0.9997 1974099 ChemDiv1_008473 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cn(CC(=O)Nc4ccccc4)c5ccccc35)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B04 compound treatment 283.1 95.4 0.5 301.6 108.0 0.56 0.7479 0.9982 1686533 ChemDiv1_008474 CCCC(=O)Nc1nc(S)c(C#N)c(c1C#N)c2ccc(OC(=O)CCC)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B05 compound treatment 282.5 94.8 0.49 301.0 107.0 0.56 0.7435 0.9982 1207889 ChemDiv1_008475 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B06 compound treatment 291.5 104.0 0.54 307.6 114.0 0.59 0.8009 0.999 1974100 ChemDiv1_008476 COc1ccc(cc1)N2C(=O)/C(=C/c3cn(Cc4ccccc4)c5ccccc35)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B07 compound treatment 295.4 108.0 0.56 314.6 121.0 0.63 0.841 0.9985 1357613 ChemDiv1_008477 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)c(OC)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B08 compound treatment 285.7 98.0 0.51 309.3 115.0 0.6 0.7858 0.9968 1974101 ChemDiv1_008478 CCOc1cc(/C=C/2\NC(=S)N(C2=O)c3ccc(OC)cc3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B09 compound treatment 275.4 87.7 0.46 296.1 102.0 0.53 0.6993 0.9972 1974102 ChemDiv1_008479 CN(C)c1cc(Nc2cc(C)ccc2C)c([N+](=O)[O-])c3nonc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B10 compound treatment 275.2 87.5 0.46 298.7 105.0 0.55 0.7081 0.9961 1974103 ChemDiv1_008480 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B11 compound treatment 274.8 87.1 0.45 300.3 106.0 0.55 0.7125 0.9952 1974104 ChemDiv1_008481 Cc1c(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B12 compound treatment 276.2 88.5 0.46 293.9 100.0 0.52 0.6941 0.9982 1974105 ChemDiv1_008482 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B13 compound treatment 274.3 86.6 0.45 292.4 98.6 0.51 0.6816 0.998 1296376 ChemDiv1_008483 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3sc4CCCCCc4c3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B14 compound treatment 276.1 88.4 0.46 295.3 101.0 0.53 0.6989 0.9977 1974106 ChemDiv1_008484 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B15 compound treatment 278.8 91.1 0.47 293.0 99.2 0.52 0.7004 0.9992 1592915 ChemDiv1_008485 CCC(NC(=O)c1ccccc1NC(=O)c2ccccc2)C(=O)N3CCN(C)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B16 compound treatment 274.4 86.7 0.45 295.5 102.0 0.53 0.6934 0.997 1974107 ChemDiv1_008486 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B17 compound treatment 274.1 86.4 0.45 291.0 97.2 0.51 0.6757 0.9984 1374906 ChemDiv1_008487 Brc1ccc(cc1)C(=O)C2Oc3ccccc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B18 compound treatment 276.8 89.1 0.46 290.4 96.6 0.5 0.6835 0.9992 1974108 ChemDiv1_008488 [O-][N+](=O)c1cnc(NC(=O)/C=C/c2ccc3OCOc3c2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B19 compound treatment 275.3 87.6 0.46 290.7 96.9 0.5 0.679 0.9988 1143441 ChemDiv1_008489 Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B20 compound treatment 272.7 85.0 0.44 291.5 97.7 0.51 0.6724 0.9977 1974109 ChemDiv1_008490 Cc1[nH]c(=O)[nH]c(=O)c1CSCC(=O)OCC(=O)Nc2nc3CC(C)(C)CC(=O)c3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B21 compound treatment 278.1 90.4 0.47 281.5 87.7 0.46 0.6556 0.9999 1484624 ChemDiv1_008491 CCOC(=O)C1=C(NC(=C(C#N)C1c2cccnc2)SCC)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B22 compound treatment 280.9 93.2 0.49 286.4 92.6 0.48 0.6839 1.0 1715169 ChemDiv1_008492 Cc1ccccc1Cn2c(NC(=O)C3CCCCC3)nc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B23 mock treatment 277.7 90.0 0.47 289.4 95.6 0.5 0.6831 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 B24 mock treatment 86.2 -102.0 -0.53 81.7 -112.0 -0.58 -0.7867 -0.9989 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C01 compound treatment 286.7 99.0 0.52 301.2 107.0 0.56 0.7597 0.9992 1974110 ChemDiv1_008493 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C02 compound treatment 281.3 93.6 0.49 297.1 103.0 0.54 0.7247 0.9989 1974111 ChemDiv1_008494 Cc1cc2nnc(SCC(=O)Nc3cc(Cl)ccc3Cl)n2c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C03 compound treatment 281.4 93.7 0.49 298.9 105.0 0.55 0.7317 0.9985 1669602 ChemDiv1_008495 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc5OCOc5c4)C(=O)Nc6cccc(F)c6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C04 compound treatment 277.8 90.1 0.47 300.5 107.0 0.55 0.7243 0.9966 1974112 ChemDiv1_008496 CC(C)(C)c1ccc(cc1)c2nc3scc(c4ccccc4)c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C05 compound treatment 276.5 88.8 0.46 295.8 102.0 0.53 0.7022 0.9977 1974113 ChemDiv1_008497 Cn1c(SCC(=O)O)nnc1c2ccc(N)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C06 compound treatment 278.5 90.8 0.47 301.4 108.0 0.56 0.7302 0.9966 1717998 ChemDiv1_008498 COc1ccc(OC)c(c1)C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C07 compound treatment 275.1 87.4 0.46 299.0 105.0 0.55 0.7088 0.9959 1923328 ChemDiv1_008499 COc1ccc(cc1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C08 compound treatment 278.8 91.1 0.47 294.3 100.0 0.52 0.7052 0.9989 1468656 ChemDiv1_008500 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C09 compound treatment 281.0 93.3 0.49 303.7 110.0 0.57 0.7478 0.9968 1974114 ChemDiv1_008501 Cc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)c(C)n1c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C10 compound treatment 276.3 88.6 0.46 299.5 106.0 0.55 0.7151 0.9963 1197620 ChemDiv1_008502 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C11 compound treatment 275.7 88.0 0.46 294.2 100.0 0.52 0.6934 0.9979 1974115 ChemDiv1_008503 FS(=O)(=O)c1ccc(cc1)C2=CC(c3ccccc3)n4ncnc4N2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C12 compound treatment 275.4 87.7 0.46 299.2 105.0 0.55 0.7106 0.996 1974116 ChemDiv1_008504 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C13 compound treatment 273.3 85.6 0.45 297.5 104.0 0.54 0.6967 0.9956 1465719 ChemDiv1_008505 CCOC(=O)c1ccc(NC(=O)C2Oc3ccccc3OC2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C14 compound treatment 275.5 87.8 0.46 296.1 102.0 0.53 0.6996 0.9972 1974117 ChemDiv1_008506 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccccc3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C15 compound treatment 281.9 94.2 0.49 296.8 103.0 0.54 0.7258 0.9991 1974118 ChemDiv1_008507 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5cccs5)C(=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C16 compound treatment 275.2 87.5 0.46 295.1 101.0 0.53 0.6948 0.9975 1974119 ChemDiv1_008508 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)c4ccncc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C17 compound treatment 277.1 89.4 0.47 291.8 98.0 0.51 0.6897 0.999 1974120 ChemDiv1_008509 Nc1nc(Nc2ccc(Cl)cc2)nc(n1)c3ccc(o3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C18 compound treatment 274.5 86.8 0.45 290.2 96.4 0.5 0.6742 0.9987 1097891 ChemDiv1_008510 OC1(CC(=O)c2ccccn2)C(=O)Nc3ccccc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C19 compound treatment 275.7 88.0 0.46 287.4 93.6 0.49 0.6684 0.9996 1974121 ChemDiv1_008511 OCCN1CCN(CC1)C(=O)CSc2nnc(CCN3C(=O)c4cccc5cccc(C3=O)c45)n2c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C20 compound treatment 275.3 87.6 0.46 288.7 94.9 0.49 0.6717 0.9993 1974122 ChemDiv1_008512 O=C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56)c7ccccc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C21 compound treatment 273.7 86.0 0.45 290.2 96.4 0.5 0.6713 0.9985 1974123 ChemDiv1_008513 CCOC(=O)c1sc(NC(=O)CSc2ncnc3sc(C)c(C)c23)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C22 compound treatment 269.3 81.6 0.43 281.4 87.6 0.46 0.6227 0.9994 1974124 ChemDiv1_008514 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(Br)c(O)c(c3)[N+](=O)[O-])/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C23 mock treatment 278.0 90.3 0.47 290.3 96.5 0.5 0.6875 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 C24 mock treatment 80.0 -108.0 -0.56 79.7 -114.0 -0.59 -0.8169 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D01 compound treatment 289.6 102.0 0.53 306.6 113.0 0.59 0.7902 0.9988 1974125 ChemDiv1_008515 COc1ccc(cc1)N2C(=O)/C(=C\c3ccc(O)c(Br)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D02 compound treatment 278.1 90.4 0.47 302.3 108.0 0.56 0.732 0.996 1974126 ChemDiv1_008516 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(O)c(O)c3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D03 compound treatment 232.7 45.0 0.23 252.9 59.1 0.31 0.383 0.9911 1974127 ChemDiv1_008517 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(Cl)c(O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D04 compound treatment 286.8 99.1 0.52 304.7 111.0 0.58 0.7729 0.9985 1486303 ChemDiv1_008518 Nc1c(sc2nc(N)c(C#N)c(c3ccc(O)cc3)c12)C(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D05 compound treatment 366.0 178.0 0.93 373.5 180.0 0.93 1.3179 1.0 1580854 ChemDiv1_008519 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)cc3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D06 compound treatment 461.5 274.0 1.43 461.5 268.0 1.39 1.9937 0.9999 1974128 ChemDiv1_008520 CCN(CC)c1ccc(/C=C/2\NC(=S)N(C2=O)c3ccc(OC)cc3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D07 compound treatment 297.9 110.0 0.57 318.3 124.0 0.65 0.8638 0.9982 1338851 ChemDiv1_008521 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D08 compound treatment 279.4 91.7 0.48 301.2 107.0 0.56 0.7328 0.997 1514082 ChemDiv1_008522 CC1=C(C(NC(=O)N1)c2cc3OCOc3cc2Br)C(=O)OCc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D09 compound treatment 278.9 91.2 0.48 297.2 103.0 0.54 0.7162 0.9981 1974129 ChemDiv1_008523 Cc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D10 compound treatment 276.7 89.0 0.46 295.9 102.0 0.53 0.7033 0.9978 1974130 ChemDiv1_008524 CC(C)OCCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OCc3ccccc3)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D11 compound treatment 274.8 87.1 0.45 292.2 98.4 0.51 0.6827 0.9982 1974131 ChemDiv1_008525 [O-][N+](=O)c1c(NCc2ccccc2)cc(N3CCCCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D12 compound treatment 275.0 87.3 0.46 299.8 106.0 0.55 0.7114 0.9955 1974132 ChemDiv1_008526 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D13 compound treatment 277.7 90.0 0.47 297.8 104.0 0.54 0.714 0.9975 1320542 ChemDiv1_008527 CC1(C)Cc2c(sc3ncn4nc(Cc5ccccc5)nc4c23)C(C)(C)N1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D14 compound treatment 276.7 89.0 0.46 298.1 104.0 0.54 0.7114 0.997 1416253 ChemDiv1_008528 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)c(OCC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D15 compound treatment 273.4 85.7 0.45 293.2 99.4 0.52 0.6812 0.9974 1686441 ChemDiv1_008529 CN1CCN(CC1)C(=O)C(Cc2ccccc2)NC(=O)c3ccccc3NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D16 compound treatment 277.0 89.3 0.47 292.7 98.9 0.51 0.6927 0.9988 1190119 ChemDiv1_008530 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D17 compound treatment 276.9 89.2 0.47 294.0 100.0 0.52 0.6971 0.9984 1543171 ChemDiv1_008531 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3C(=O)c5ccc(Br)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D18 compound treatment 277.2 89.5 0.47 293.6 99.8 0.52 0.6967 0.9986 1633665 ChemDiv1_008532 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D19 compound treatment 273.8 86.1 0.45 290.7 96.9 0.5 0.6735 0.9984 1644998 ChemDiv1_008533 Nc1c(sc2nc3CCCCc3cc12)C(=O)Nc4ccc5ccccc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D20 compound treatment 281.2 93.5 0.49 296.3 102.0 0.53 0.7214 0.999 1974133 ChemDiv1_008534 COc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C4(CC5CC6CC(C5)C4)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D21 compound treatment 276.3 88.6 0.46 286.5 92.7 0.48 0.6673 0.9998 1137703 ChemDiv1_008535 CCOC(=O)C1=C(NC(=C(C#N)C1c2cccnc2)SC)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D22 compound treatment 270.5 82.8 0.43 285.6 91.8 0.48 0.6426 0.9988 1450518 ChemDiv1_008536 O=C(Nc1nc2ccccc2n1CCN3CCCC3)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D23 mock treatment 277.9 90.2 0.47 291.7 97.9 0.51 0.6923 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 D24 mock treatment 80.5 -107.0 -0.56 84.9 -109.0 -0.57 -0.7959 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E01 compound treatment 284.0 96.3 0.5 298.2 104.0 0.54 0.7387 0.9993 1974134 ChemDiv1_008537 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccccc4C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E02 compound treatment 278.7 91.0 0.47 300.2 106.0 0.55 0.7265 0.9971 1974135 ChemDiv1_008538 Cc1nc(SCC(=O)Nc2sc3CCCc3c2C(=O)N)c4c5CCCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E03 compound treatment 285.8 98.1 0.51 301.1 107.0 0.56 0.756 0.9991 1974136 ChemDiv1_008539 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E04 compound treatment 284.1 96.4 0.5 301.8 108.0 0.56 0.7523 0.9985 1974137 ChemDiv1_008540 CC(C)(C)c1ccc(cc1)c2nc3sc4CCCc4c3c(=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E05 compound treatment 283.4 95.7 0.5 303.4 110.0 0.57 0.7556 0.9978 1554138 ChemDiv1_008541 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCC(=O)c4ccc(Cl)cc4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E06 compound treatment 279.6 91.9 0.48 301.2 107.0 0.56 0.7335 0.9971 1289342 ChemDiv1_008542 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E07 compound treatment 276.5 88.8 0.46 301.0 107.0 0.56 0.7213 0.9958 1923360 ChemDiv1_008543 COc1ccc(cc1)N(CC(=O)Nc2cc(OC)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E08 compound treatment 277.7 90.0 0.47 298.0 104.0 0.54 0.7147 0.9975 1267641 ChemDiv1_008544 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E09 compound treatment 281.1 93.4 0.49 301.1 107.0 0.56 0.7387 0.9977 1974138 ChemDiv1_008545 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E10 compound treatment 279.0 91.3 0.48 306.2 112.0 0.58 0.7497 0.9948 1640155 ChemDiv1_008546 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E11 compound treatment 280.7 93.0 0.48 302.9 109.0 0.57 0.7438 0.997 1974139 ChemDiv1_008547 Clc1ccc(/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccc(Cl)cc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E12 compound treatment 277.3 89.6 0.47 300.8 107.0 0.56 0.7235 0.9962 1974140 ChemDiv1_008548 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E13 compound treatment 277.7 90.0 0.47 298.2 104.0 0.54 0.7155 0.9974 1205423 ChemDiv1_008549 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc(Cl)c(Cl)c3)c4ccc(O)c(O)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E14 compound treatment 279.4 91.7 0.48 293.8 100.0 0.52 0.7056 0.9991 1633266 ChemDiv1_008550 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4ccccc4nc3Cl)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E15 compound treatment 277.6 89.9 0.47 295.5 102.0 0.53 0.7052 0.9982 1714137 ChemDiv1_008551 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5cccs5)C(=O)c6cc(OC)c(OC)c(OC)c6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E16 compound treatment 278.0 90.3 0.47 294.4 101.0 0.52 0.7026 0.9986 1974141 ChemDiv1_008552 COc1ccccc1C2CC(=NN2C(=O)c3ccncc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E17 compound treatment 276.8 89.1 0.46 298.2 104.0 0.54 0.7121 0.997 1974142 ChemDiv1_008553 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCc2c[nH]c3ccccc23)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E18 compound treatment 271.7 84.0 0.44 293.7 99.9 0.52 0.6768 0.9964 1130606 ChemDiv1_008554 Cn1c(SCC(=O)NC2CCCCC2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E19 compound treatment 277.1 89.4 0.47 298.0 104.0 0.54 0.7125 0.9972 1974143 ChemDiv1_008555 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCCN4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E20 compound treatment 277.4 89.7 0.47 292.0 98.2 0.51 0.6916 0.9991 1676953 ChemDiv1_008556 CCOC(=O)N1C(=O)c2cc(OC)ccc2S1(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E21 compound treatment 280.7 93.0 0.48 288.3 94.5 0.49 0.6901 1.0 1974144 ChemDiv1_008557 Cc1sc2nc(/C=C/c3ccco3)oc(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E22 compound treatment 273.4 85.7 0.45 288.3 94.5 0.49 0.6632 0.9989 1974145 ChemDiv1_008558 COC(=O)Cn1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)c(C)c3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E23 mock treatment 277.0 89.3 0.47 289.2 95.4 0.5 0.6798 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 E24 mock treatment 76.5 -111.0 -0.58 78.7 -115.0 -0.6 -0.8335 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F01 compound treatment 279.9 92.2 0.48 295.2 101.0 0.53 0.7125 0.9989 1974146 ChemDiv1_008559 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(o3)c4ccccc4[N+](=O)[O-])/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F02 compound treatment 280.4 92.7 0.48 302.4 109.0 0.56 0.7409 0.997 1974147 ChemDiv1_008560 Nc1nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])c(C#N)c(Cc3ccccc3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F03 compound treatment 283.8 96.1 0.5 305.3 111.0 0.58 0.7641 0.9974 1974148 ChemDiv1_008561 OC(=O)Cn1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3F)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F04 compound treatment 282.9 95.2 0.5 306.2 112.0 0.58 0.764 0.9967 1143186 ChemDiv1_008562 COc1cc(c(Cl)cc1O)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F05 compound treatment 286.0 98.3 0.51 310.3 116.0 0.61 0.7905 0.9966 1378478 ChemDiv1_008563 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(O)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F06 compound treatment 278.0 90.3 0.47 300.7 107.0 0.56 0.7258 0.9966 1974149 ChemDiv1_008564 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCc4ccc(cc4)C(=O)O)cc3)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F07 compound treatment 281.4 93.7 0.49 301.1 107.0 0.56 0.7398 0.9978 1627524 ChemDiv1_008565 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F08 compound treatment 280.9 93.2 0.49 299.7 106.0 0.55 0.7328 0.9981 1974150 ChemDiv1_008566 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F09 compound treatment 276.8 89.1 0.46 299.5 106.0 0.55 0.7169 0.9965 1974151 ChemDiv1_008567 Cc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F10 compound treatment 277.3 89.6 0.47 299.5 106.0 0.55 0.7188 0.9967 1974152 ChemDiv1_008568 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F11 compound treatment 280.4 92.7 0.48 300.5 107.0 0.55 0.7339 0.9977 1974153 ChemDiv1_008569 Oc1ccc(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F12 compound treatment 277.9 90.2 0.47 299.2 105.0 0.55 0.7199 0.9971 1974154 ChemDiv1_008570 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F13 compound treatment 278.0 90.3 0.47 298.1 104.0 0.54 0.7162 0.9975 1650532 ChemDiv1_008571 COc1ccccc1c2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F14 compound treatment 279.4 91.7 0.48 297.3 103.0 0.54 0.7184 0.9983 1167672 ChemDiv1_008572 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cc(OC)ccc4OC)C(=O)OCC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F15 compound treatment 275.8 88.1 0.46 295.6 102.0 0.53 0.6989 0.9975 1526810 ChemDiv1_008573 Cc1ccnc(c1)n2c(CCCN3C(=O)c4ccccc4C3=O)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F16 compound treatment 274.5 86.8 0.45 293.8 100.0 0.52 0.6875 0.9976 1974155 ChemDiv1_008574 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F17 compound treatment 281.1 93.4 0.49 303.5 110.0 0.57 0.7475 0.9969 1461307 ChemDiv1_008575 COc1ccccc1C2Oc3ccc(Cl)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F18 compound treatment 275.8 88.1 0.46 292.2 98.4 0.51 0.6864 0.9986 1717441 ChemDiv1_008576 CN(C(=O)C)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F19 compound treatment 275.7 88.0 0.46 293.4 99.6 0.52 0.6904 0.9982 1974156 ChemDiv1_008577 Nc1c(sc2nc3CCCc3cc12)C(=O)Nc4cc(ccc4Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F20 compound treatment 275.5 87.8 0.46 295.0 101.0 0.53 0.6956 0.9976 1974157 ChemDiv1_008578 O=C(COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C3(CC4CC5CC(C4)C3)C5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F21 compound treatment 276.1 88.4 0.46 287.9 94.1 0.49 0.6717 0.9996 1974158 ChemDiv1_008579 CCCCOC(=O)CSC1=C(C#N)C(C(=C(N1)c2ccccc2)C(=O)OCC)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F22 compound treatment 273.6 85.9 0.45 288.3 94.5 0.49 0.6639 0.9989 1500655 ChemDiv1_008580 O=C(Nc1nc2ccccc2n1CCN3CCCCC3)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F23 mock treatment 278.2 90.5 0.47 287.6 93.8 0.49 0.6783 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 F24 mock treatment 76.9 -111.0 -0.58 83.5 -110.0 -0.57 -0.8144 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G01 compound treatment 285.2 97.5 0.51 301.6 108.0 0.56 0.7556 0.9988 1974159 ChemDiv1_008581 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G02 compound treatment 285.4 97.7 0.51 300.8 107.0 0.56 0.7534 0.999 1472611 ChemDiv1_008582 CC(=O)Nc1cccc(Oc2nnc(c3ccc(C)c(C)c3)c4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G03 compound treatment 280.2 92.5 0.48 298.8 105.0 0.55 0.7269 0.9981 1204046 ChemDiv1_008583 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5ccccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G04 compound treatment 285.7 98.0 0.51 298.7 105.0 0.55 0.7468 0.9995 1648336 ChemDiv1_008584 C=CCn1c(SCC(=O)NC2CCCCC2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G05 compound treatment 284.8 97.1 0.51 300.4 107.0 0.55 0.7497 0.999 1974160 ChemDiv1_008585 CN(CCOC(=O)c1ccc2OCCOc2c1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G06 compound treatment 279.9 92.2 0.48 299.7 106.0 0.55 0.7291 0.9977 1675890 ChemDiv1_008586 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G07 compound treatment 422.6 235.0 1.23 419.5 226.0 1.17 1.6958 0.9998 1974161 ChemDiv1_008587 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)c(Br)cc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G08 compound treatment 276.9 89.2 0.47 299.7 106.0 0.55 0.718 0.9965 1146967 ChemDiv1_008588 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G09 compound treatment 277.8 90.1 0.47 296.9 103.0 0.54 0.711 0.9979 1974162 ChemDiv1_008589 CCOc1cc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)ccc1OCC(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G10 compound treatment 275.2 87.5 0.46 297.9 104.0 0.54 0.7051 0.9964 1974163 ChemDiv1_008590 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G11 compound treatment 279.0 91.3 0.48 297.9 104.0 0.54 0.7192 0.998 1865646 ChemDiv1_008591 Fc1ccc(/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccc(F)cc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G12 compound treatment 271.4 83.7 0.44 296.4 103.0 0.53 0.6856 0.9951 1974164 ChemDiv1_008592 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G13 compound treatment 281.7 94.0 0.49 299.5 106.0 0.55 0.735 0.9984 1553890 ChemDiv1_008593 COc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(Cl)c(Cl)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G14 compound treatment 277.7 90.0 0.47 297.5 104.0 0.54 0.7129 0.9976 1287317 ChemDiv1_008594 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4ccccc4nc3Cl)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G15 compound treatment 279.7 92.0 0.48 295.9 102.0 0.53 0.7144 0.9987 1513887 ChemDiv1_008595 COc1cccc(c1)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C4)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G16 compound treatment 274.7 87.0 0.45 296.0 102.0 0.53 0.6963 0.9969 1224926 ChemDiv1_008596 Fc1ccc(cc1)C2CC(=NN2C(=O)c3cccs3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G17 compound treatment 278.0 90.3 0.47 300.7 107.0 0.56 0.7258 0.9966 1232850 ChemDiv1_008597 COc1ccc(CCN2C(Nc3ccccc3C2=O)c4ccc(cc4)N(C)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G18 compound treatment 276.2 88.5 0.46 296.1 102.0 0.53 0.7022 0.9975 1172732 ChemDiv1_008598 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5ccc(OC(C)C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G19 compound treatment 276.1 88.4 0.46 289.9 96.1 0.5 0.679 0.9992 1974165 ChemDiv1_008599 OCCCNC(=O)CSc1nnc(CCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G20 compound treatment 277.7 90.0 0.47 291.4 97.6 0.51 0.6905 0.9992 1544594 ChemDiv1_008600 CCOC(=O)N1C(=O)c2cc(OCC)ccc2S1(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G21 compound treatment 277.1 89.4 0.47 292.7 98.9 0.51 0.693 0.9988 1974166 ChemDiv1_008601 Cc1nc(SCC(=O)Nc2ccccc2F)c3c4CCCCc4sc3n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G22 compound treatment 276.9 89.2 0.47 286.9 93.1 0.48 0.671 0.9998 1974167 ChemDiv1_008602 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)c(C)c3)ccc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G23 mock treatment 278.1 90.4 0.47 290.0 96.2 0.5 0.6868 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 G24 mock treatment 82.2 -106.0 -0.55 88.1 -106.0 -0.55 -0.7779 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H01 compound treatment 298.7 111.0 0.58 315.0 121.0 0.63 0.8547 0.9991 1974168 ChemDiv1_008603 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(cc3)N(CC)CC)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H02 compound treatment 282.6 94.9 0.49 303.8 110.0 0.57 0.7541 0.9974 1974169 ChemDiv1_008604 Cc1nc(SC2CCCCC2=O)c(C#N)c(c3cccs3)c1C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H03 compound treatment 318.8 131.0 0.68 345.0 151.0 0.79 1.0391 0.9976 1137375 ChemDiv1_008605 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)c(OC)c3)c(=O)n2C1c4ccccc4OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H04 compound treatment 278.3 90.6 0.47 300.7 107.0 0.56 0.7269 0.9967 1974170 ChemDiv1_008606 O=C(Oc1ccc(/C=C/2\S/C(=N\c3ccc4OCOc4c3)/N(C2=O)c5ccc6OCOc6c5)cc1)N7CCOCC7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H05 compound treatment 290.8 103.0 0.54 313.0 119.0 0.62 0.8182 0.9975 1714964 ChemDiv1_008607 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5ccc(OCC)c(OCC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H06 compound treatment 277.3 89.6 0.47 303.8 110.0 0.57 0.7346 0.995 1974171 ChemDiv1_008608 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(OC)cc3Cl)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H07 compound treatment 276.2 88.5 0.46 299.0 105.0 0.55 0.7129 0.9964 1372725 ChemDiv1_008609 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4cc(OC)ccc4OC)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H08 compound treatment 279.7 92.0 0.48 300.2 106.0 0.55 0.7302 0.9975 1974172 ChemDiv1_008610 CCCOc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)OCCSCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H09 compound treatment 272.7 85.0 0.44 300.6 107.0 0.56 0.7058 0.9938 1974173 ChemDiv1_008611 CC1CCCN(C1)c2cc(Nc3ccc(C)cc3C)c([N+](=O)[O-])c4nonc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H10 compound treatment 276.7 89.0 0.46 298.6 105.0 0.54 0.7132 0.9968 1974174 ChemDiv1_008612 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Cl)C(=O)CC(C2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H11 compound treatment 277.2 89.5 0.47 301.0 107.0 0.56 0.7239 0.9961 1974175 ChemDiv1_008613 [O-][N+](=O)c1c(NCc2ccccc2)cc(N3CCOCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H12 compound treatment 276.4 88.7 0.46 301.4 108.0 0.56 0.7224 0.9955 1974176 ChemDiv1_008614 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H13 compound treatment 279.1 91.4 0.48 299.1 105.0 0.55 0.7239 0.9976 1130318 ChemDiv1_008615 COc1ccc(cc1OC)c2nc3c4c5CCCCCc5sc4ncn3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H14 compound treatment 272.3 84.6 0.44 293.7 99.9 0.52 0.679 0.9967 1974177 ChemDiv1_008616 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H15 compound treatment 274.8 87.1 0.45 297.1 103.0 0.54 0.7007 0.9965 1974178 ChemDiv1_008617 O=C(CCN1C(=O)c2ccccc2C1=O)NCCCn3ccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H16 compound treatment 277.4 89.7 0.47 296.2 102.0 0.53 0.707 0.9979 1974179 ChemDiv1_008618 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc5OCOc5c4)C(=O)OCCOc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H17 compound treatment 279.9 92.2 0.48 296.5 103.0 0.53 0.7173 0.9986 1974180 ChemDiv1_008619 COc1ccc(cc1)C2=NN3COc4ccc(Br)cc4C3C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H18 compound treatment 280.5 92.8 0.48 294.6 101.0 0.52 0.7126 0.9992 1402297 ChemDiv1_008620 O=C(N1CCN(Cc2ccc3OCOc3c2)CC1)c4cc(nc5ccccc45)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H19 compound treatment 274.7 87.0 0.45 289.3 95.5 0.5 0.6717 0.999 1584494 ChemDiv1_008621 COc1ccccc1NC(=O)c2c(C)nc3sc(C(=O)N)c(N)c3c2c4ccc(C)s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H20 compound treatment 281.9 94.2 0.49 293.7 99.9 0.52 0.7144 0.9996 1515443 ChemDiv1_008622 CCn1c(NC(=O)C2CCCCC2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H21 compound treatment 278.5 90.8 0.47 291.0 97.2 0.51 0.6919 0.9995 1974181 ChemDiv1_008623 CC(=O)c1cc(C#N)c(SCCCCSc2nc(C)c(cc2C#N)C(=O)C)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H22 compound treatment 276.6 88.9 0.46 288.5 94.7 0.49 0.6757 0.9996 1699522 ChemDiv1_008624 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(N4CCOCC4)c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H23 mock treatment 276.5 88.8 0.46 291.9 98.1 0.51 0.6879 0.9988 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 H24 mock treatment 74.4 -113.0 -0.59 87.8 -106.0 -0.55 -0.8078 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I01 compound treatment 282.6 94.9 0.49 305.7 112.0 0.58 0.7611 0.9968 1974182 ChemDiv1_008625 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5ccccc5C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I02 compound treatment 285.3 97.6 0.51 299.3 105.0 0.55 0.7475 0.9993 1974183 ChemDiv1_008626 COC(=O)c1cc(cc(c1)n2c(C)cc(C(=O)CSc3nnc4cc(C)c5ccccc5n34)c2C)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I03 compound treatment 283.8 96.1 0.5 301.5 108.0 0.56 0.7501 0.9985 1245633 ChemDiv1_008627 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4cccnc4)C(=O)Nc5cccc(F)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I04 compound treatment 280.9 93.2 0.49 298.2 104.0 0.54 0.7273 0.9985 1974184 ChemDiv1_008628 Cc1nc(SCC(=O)Nc2ccc3OCCOc3c2)c4c5CCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I05 compound treatment 279.1 91.4 0.48 299.9 106.0 0.55 0.7269 0.9974 1974185 ChemDiv1_008629 OC(=O)CSc1nnc([nH]1)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I06 compound treatment 277.9 90.2 0.47 299.1 105.0 0.55 0.7195 0.9972 1682381 ChemDiv1_008630 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I07 compound treatment 282.2 94.5 0.49 304.9 111.0 0.58 0.7567 0.9969 1974186 ChemDiv1_008631 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)c(Br)cc1OCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I08 compound treatment 279.9 92.2 0.48 305.1 111.0 0.58 0.7489 0.9958 1599258 ChemDiv1_008632 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I09 compound treatment 278.7 91.0 0.47 305.1 111.0 0.58 0.7445 0.9952 1974187 ChemDiv1_008633 COC(=O)COc1ccc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I10 compound treatment 278.3 90.6 0.47 297.1 103.0 0.54 0.7136 0.998 1974188 ChemDiv1_008634 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I11 compound treatment 275.4 87.7 0.46 298.1 104.0 0.54 0.7066 0.9964 1690814 ChemDiv1_008635 Clc1ccc(cc1)C2C3=C(Nc4ncnn24)c5ccccc5CCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I12 compound treatment 278.1 90.4 0.47 305.5 112.0 0.58 0.7438 0.9947 1443897 ChemDiv1_008636 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccs3)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I13 compound treatment 276.2 88.5 0.46 302.3 108.0 0.56 0.725 0.995 1974189 ChemDiv1_008637 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(C)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I14 compound treatment 279.5 91.8 0.48 296.4 103.0 0.53 0.7155 0.9985 1389162 ChemDiv1_008638 OC(=O)CCCC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I15 compound treatment 274.3 86.6 0.45 294.5 101.0 0.52 0.6893 0.9973 1787324 ChemDiv1_008639 OC(=O)CCC(=O)N1C(C2=C(CC(CC2=O)c3ccc(F)cc3)Nc4ccccc14)c5ccc(o5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I16 compound treatment 283.6 95.9 0.5 301.1 107.0 0.56 0.7479 0.9985 1620168 ChemDiv1_008640 Fc1ccc(cc1)C2CC(=NN2C(=O)c3cccnc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I17 compound treatment 277.7 90.0 0.47 299.1 105.0 0.55 0.7188 0.9971 1690452 ChemDiv1_008641 Cc1nc(Nc2ccc(cc2)S(=O)(=O)N)nc(Nc3ccc(cc3)S(=O)(=O)N)c1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I18 compound treatment 280.3 92.6 0.48 298.8 105.0 0.55 0.7273 0.9981 1974190 ChemDiv1_008642 CCCCOc1ccc(cc1)C2Oc3ccc(OC)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I19 compound treatment 278.5 90.8 0.47 294.4 101.0 0.52 0.7044 0.9988 1944230 ChemDiv1_008643 CCOc1ccc(CC2S/C(=N/c3ccc(cc3)C(=O)O)/N(CC=C)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I20 compound treatment 277.2 89.5 0.47 289.2 95.4 0.5 0.6805 0.9995 1667484 ChemDiv1_008644 COc1ccc(NC(=O)C2Oc3ccccc3OC2C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I21 compound treatment 274.4 86.7 0.45 290.6 96.8 0.5 0.6754 0.9986 1974191 ChemDiv1_008645 COC(=O)c1sc(NC(=O)CSc2ncnc3sc(C)c(C)c23)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I22 compound treatment 279.8 92.1 0.48 290.4 96.6 0.5 0.6945 0.9998 1974192 ChemDiv1_008646 COc1ccc(OC)c(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)c(C)c3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I23 mock treatment 282.0 94.3 0.49 292.6 98.8 0.51 0.7107 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 I24 mock treatment 76.4 -111.0 -0.58 93.1 -101.0 -0.52 -0.7809 -0.9987 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J01 compound treatment 281.8 94.1 0.49 299.4 106.0 0.55 0.735 0.9984 1974193 ChemDiv1_008647 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(o3)c4cccc(c4)[N+](=O)[O-])/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J02 compound treatment 281.1 93.4 0.49 299.0 105.0 0.55 0.7309 0.9983 1974194 ChemDiv1_008648 Cc1cc(C)c(C#N)c(SCC(=O)Nc2cccc3cccnc23)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J03 compound treatment 281.2 93.5 0.49 301.9 108.0 0.56 0.742 0.9975 1297893 ChemDiv1_008649 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(NC(=O)C)cc3)c(=O)n2C1c4ccccc4OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J04 compound treatment 279.9 92.2 0.48 298.0 104.0 0.54 0.7228 0.9982 1393149 ChemDiv1_008650 Cc1cc2nc3sc(=Cc4ccc(OC(=O)N5CCOCC5)cc4)c(=O)n3c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J05 compound treatment 365.1 177.0 0.93 391.2 197.0 1.03 1.3797 0.9987 1251601 ChemDiv1_008651 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J06 compound treatment 283.7 96.0 0.5 304.8 111.0 0.58 0.7618 0.9975 1974195 ChemDiv1_008652 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(OC)c3)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J07 compound treatment 278.9 91.2 0.48 301.1 107.0 0.56 0.7305 0.9969 1974196 ChemDiv1_008653 COc1ccc2nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccccc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J08 compound treatment 282.0 94.3 0.49 299.4 106.0 0.55 0.7357 0.9985 1974197 ChemDiv1_008654 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3F)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J09 compound treatment 279.4 91.7 0.48 299.2 105.0 0.55 0.7254 0.9977 1974198 ChemDiv1_008655 CC1CCCN(C1)c2cc(Nc3ccc(C)c(C)c3)c([N+](=O)[O-])c4nonc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J10 compound treatment 278.3 90.6 0.47 299.5 106.0 0.55 0.7224 0.9972 1974199 ChemDiv1_008656 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J11 compound treatment 275.3 87.6 0.46 295.6 102.0 0.53 0.697 0.9973 1974200 ChemDiv1_008657 Cc1ccccc1Nc2cc(N3CCCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J12 compound treatment 279.4 91.7 0.48 294.7 101.0 0.52 0.7089 0.9989 1974201 ChemDiv1_008658 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)c(OCC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J13 compound treatment 274.7 87.0 0.45 299.0 105.0 0.55 0.7073 0.9957 1643674 ChemDiv1_008659 C(Sc1nc2ccccc2o1)c3nc4c5c6CCCCCc6sc5ncn4n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J14 compound treatment 274.8 87.1 0.45 297.6 104.0 0.54 0.7026 0.9963 1974202 ChemDiv1_008660 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J15 compound treatment 281.5 93.8 0.49 301.6 108.0 0.56 0.742 0.9977 1656095 ChemDiv1_008661 Brc1ccc(NC(=O)CCN2C(=O)c3ccccc3C2=O)nc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J16 compound treatment 276.2 88.5 0.46 296.3 102.0 0.53 0.7029 0.9974 1974203 ChemDiv1_008662 CCOCCOC(=O)C1=C(C)NC(=O)NC1c2cccc(OCc3ccccc3)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J17 compound treatment 288.8 101.0 0.53 307.9 114.0 0.59 0.7921 0.9983 1490647 ChemDiv1_008663 Brc1ccc2OC3(CCCC3)N4N=C(CC4c2c1)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J18 compound treatment 280.4 92.7 0.48 295.4 102.0 0.53 0.7151 0.999 1400777 ChemDiv1_008664 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)C)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J19 compound treatment 276.7 89.0 0.46 297.0 103.0 0.54 0.7074 0.9974 1974204 ChemDiv1_008665 CCOC(=O)c1cc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)C)nc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J20 compound treatment 275.2 87.5 0.46 291.3 97.5 0.51 0.6809 0.9986 1485192 ChemDiv1_008666 CCCCn1c(NC(=O)C2CCCCC2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J21 compound treatment 275.3 87.6 0.46 293.2 99.4 0.52 0.6882 0.9981 1974205 ChemDiv1_008667 CC(=O)c1cc(C#N)c(SCC(=O)c2cc3ccccc3oc2=O)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J22 compound treatment 277.9 90.2 0.47 290.9 97.1 0.5 0.6894 0.9994 1382070 ChemDiv1_008668 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(NCc4ccccc4)c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J23 mock treatment 276.7 89.0 0.46 291.4 97.6 0.51 0.6868 0.999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 J24 mock treatment 82.3 -105.0 -0.55 82.5 -111.0 -0.58 -0.7981 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K01 compound treatment 287.2 99.5 0.52 310.4 117.0 0.61 0.7953 0.997 1974206 ChemDiv1_008669 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5cccc(c5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K02 compound treatment 283.7 96.0 0.5 298.2 104.0 0.54 0.7376 0.9992 1974207 ChemDiv1_008670 Clc1ccc(cc1)c2csc3ncnc(NCCCN4CCOCC4)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K03 compound treatment 278.6 90.9 0.47 297.5 104.0 0.54 0.7162 0.9979 1974208 ChemDiv1_008671 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4cccnc4)C(=O)Nc5ccccc5C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K04 compound treatment 280.1 92.4 0.48 301.3 107.0 0.56 0.7357 0.9973 1974209 ChemDiv1_008672 Fc1ccccc1NC(=O)CSc2nnc3sc4ccccc4n23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K05 compound treatment 282.2 94.5 0.49 298.8 105.0 0.55 0.7343 0.9987 1974210 ChemDiv1_008673 OC(=O)CSc1ncn(n1)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K06 compound treatment 279.6 91.9 0.48 301.7 108.0 0.56 0.7353 0.9969 1173097 ChemDiv1_008674 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K07 compound treatment 281.6 93.9 0.49 298.7 105.0 0.55 0.7317 0.9986 1974211 ChemDiv1_008675 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K08 compound treatment 283.9 96.2 0.5 304.1 110.0 0.57 0.76 0.9978 1404508 ChemDiv1_008676 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K09 compound treatment 278.7 91.0 0.47 303.6 110.0 0.57 0.739 0.9958 1974212 ChemDiv1_008677 Cc1cc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)c(C)n1c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K10 compound treatment 281.0 93.3 0.49 299.7 106.0 0.55 0.7331 0.9981 1974213 ChemDiv1_008678 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K11 compound treatment 275.2 87.5 0.46 299.9 106.0 0.55 0.7125 0.9956 1974214 ChemDiv1_008679 ClC1=CCC2C(C1)C(=O)N(CCCCCCN3C(=O)C4CC=C(Cl)CC4C3=O)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K12 compound treatment 277.8 90.1 0.47 299.2 105.0 0.55 0.7195 0.9971 1510679 ChemDiv1_008680 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)C(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K13 compound treatment 274.4 86.7 0.45 299.8 106.0 0.55 0.7092 0.9952 1787330 ChemDiv1_008681 COc1cccc(c1)C2N(C(=O)C3CC3)c4ccccc4NC5=C2C(=O)CC(C5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K14 compound treatment 279.9 92.2 0.48 300.8 107.0 0.56 0.7331 0.9974 1736666 ChemDiv1_008682 Cc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCCC(=O)O)c4cccs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K15 compound treatment 287.8 100.0 0.52 307.1 113.0 0.59 0.7854 0.9982 1974215 ChemDiv1_008683 O=C1CCCN1CCCN/C=C\2/C(=O)N(N=C2c3ccccc3)c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K16 compound treatment 277.1 89.4 0.47 297.8 104.0 0.54 0.7118 0.9973 1682550 ChemDiv1_008684 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K17 compound treatment 276.5 88.8 0.46 295.5 102.0 0.53 0.7011 0.9978 1390449 ChemDiv1_008685 COc1ccc2[nH]c3C(CC(C)CCC=C(C)C)NCCc3c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K18 compound treatment 277.2 89.5 0.47 297.3 103.0 0.54 0.7103 0.9975 1974216 ChemDiv1_008686 CCCCCCOc1ccc(cc1)C2Oc3ccc(OC)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K19 compound treatment 283.2 95.5 0.5 294.8 101.0 0.52 0.7232 0.9997 1974217 ChemDiv1_008687 O=C(CSc1nnc2sc3ccccc3n12)c4cccc5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K20 compound treatment 281.5 93.8 0.49 293.3 99.5 0.52 0.7115 0.9996 1974218 ChemDiv1_008688 N#CC1(CCc2c(C1)sc3ncnc(N4CCOCC4)c23)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K21 compound treatment 276.8 89.1 0.46 292.4 98.6 0.51 0.6908 0.9988 1974219 ChemDiv1_008689 Cc1cc2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K22 compound treatment 278.5 90.8 0.47 289.1 95.3 0.5 0.685 0.9997 1974220 ChemDiv1_008690 Brc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K23 mock treatment 278.4 90.7 0.47 289.1 95.3 0.5 0.6846 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 K24 mock treatment 79.0 -109.0 -0.57 84.2 -110.0 -0.57 -0.8041 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L01 compound treatment 284.8 97.1 0.51 300.0 106.0 0.55 0.7483 0.9991 1974221 ChemDiv1_008691 CCOc1cccc(c1)N2C(=O)/C(=C\c3c(C)nn(c3O)c4ccccc4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L02 compound treatment 284.5 96.8 0.5 304.7 111.0 0.58 0.7644 0.9978 1974222 ChemDiv1_008692 Nc1nc(SCC(=O)c2ccc(Br)cc2)c(C#N)c(c3cccs3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L03 compound treatment 282.9 95.2 0.5 304.7 111.0 0.58 0.7585 0.9972 1191496 ChemDiv1_008693 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccccc4OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L04 compound treatment 282.5 94.8 0.49 296.6 103.0 0.53 0.7273 0.9992 1307524 ChemDiv1_008694 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Cl)c1OCc5cccc(c5)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L05 compound treatment 277.5 89.8 0.47 292.6 98.8 0.51 0.6941 0.9989 1165808 ChemDiv1_008695 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L06 compound treatment 277.5 89.8 0.47 303.8 110.0 0.57 0.7353 0.9951 1974223 ChemDiv1_008696 COc1ccc(cc1)N2C(=O)/C(=C/c3cc4OCOc4cc3Cl)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L07 compound treatment 281.3 93.6 0.49 297.6 104.0 0.54 0.7265 0.9987 1974224 ChemDiv1_008697 Cc1ccc2nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccccc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L08 compound treatment 281.2 93.5 0.49 301.7 108.0 0.56 0.7412 0.9976 1231680 ChemDiv1_008698 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4cc5OCOc5cc4Br)C(=O)CC(C)(C)C3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L09 compound treatment 277.7 90.0 0.47 297.5 104.0 0.54 0.7129 0.9976 1974225 ChemDiv1_008699 [O-][N+](=O)c1c(Nc2ccccc2Cl)cc(N3CCOCC3)c4nonc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L10 compound treatment 282.3 94.6 0.49 297.4 104.0 0.54 0.7295 0.999 1974226 ChemDiv1_008700 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L11 compound treatment 275.0 87.3 0.46 300.1 106.0 0.55 0.7125 0.9954 1786639 ChemDiv1_008701 OC(=O)c1n[nH]c(=O)c2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L12 compound treatment 277.1 89.4 0.47 297.3 103.0 0.54 0.7099 0.9975 1974227 ChemDiv1_008702 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L13 compound treatment 276.5 88.8 0.46 297.2 103.0 0.54 0.7074 0.9972 1368267 ChemDiv1_008703 COc1ccc(Cc2nc3c4c5CCCCCc5sc4ncn3n2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L14 compound treatment 280.4 92.7 0.48 301.1 107.0 0.56 0.7361 0.9975 1974228 ChemDiv1_008704 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L15 compound treatment 276.8 89.1 0.46 296.3 102.0 0.53 0.7052 0.9977 1666167 ChemDiv1_008705 Cn1c(=O)n(C)c2nc(S)n(CC3CC3)c2c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L16 compound treatment 277.4 89.7 0.47 299.1 105.0 0.55 0.7177 0.9969 1974229 ChemDiv1_008706 COCCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(O)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L17 compound treatment 287.7 100.0 0.52 306.6 113.0 0.59 0.7832 0.9983 1974230 ChemDiv1_008707 Clc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L18 compound treatment 279.6 91.9 0.48 293.6 99.8 0.52 0.7056 0.9992 1974231 ChemDiv1_008708 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)/C=C/c3ccc4OCOc4c3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L19 compound treatment 275.3 87.6 0.46 291.9 98.1 0.51 0.6834 0.9985 1138097 ChemDiv1_008709 CCOc1ccc(cc1)C(=O)c2sc3nc(N)c(C#N)c(CC)c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L20 compound treatment 276.3 88.6 0.46 289.0 95.2 0.49 0.6765 0.9994 1712663 ChemDiv1_008710 C=CCn1c(NC(=O)C2CCCCC2)nc3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L21 compound treatment 278.5 90.8 0.47 291.6 97.8 0.51 0.6941 0.9994 1974232 ChemDiv1_008711 Nc1nc(SCC(=O)c2ccccc2)c(C#N)c(c1C#N)c3ccc(O)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L22 compound treatment 279.7 92.0 0.48 286.9 93.1 0.48 0.6813 1.0 1320992 ChemDiv1_008712 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(NCc4nc5ccccc5[nH]4)c6ccccc36 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L23 mock treatment 282.9 95.2 0.5 284.6 90.8 0.47 0.6847 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 L24 mock treatment 77.2 -111.0 -0.58 80.8 -113.0 -0.59 -0.8232 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M01 compound treatment 291.4 104.0 0.54 312.8 119.0 0.62 0.8197 0.9978 1852718 ChemDiv1_008713 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5cccc(F)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M02 compound treatment 282.1 94.4 0.49 297.9 104.0 0.54 0.7306 0.9989 1974233 ChemDiv1_008714 FC(F)(F)c1cccc(Oc2nnc(c3ccccc3)c4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M03 compound treatment 279.9 92.2 0.48 299.0 105.0 0.55 0.7265 0.9979 1974234 ChemDiv1_008715 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4cccnc4)C(=O)Nc5cccc(c5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M04 compound treatment 279.4 91.7 0.48 295.6 102.0 0.53 0.7122 0.9987 1974235 ChemDiv1_008716 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc3sc4ccccc4n23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M05 compound treatment 277.8 90.1 0.47 296.4 103.0 0.53 0.7092 0.998 1914555 ChemDiv1_008717 OC(=O)CSc1nncn1c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M06 compound treatment 274.5 86.8 0.45 298.6 105.0 0.54 0.7051 0.9958 1280312 ChemDiv1_008718 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M07 compound treatment 354.9 167.0 0.87 376.7 183.0 0.95 1.2888 0.9991 1974236 ChemDiv1_008719 Oc1ccc(Br)cc1/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M08 compound treatment 281.3 93.6 0.49 297.7 104.0 0.54 0.7269 0.9987 1225381 ChemDiv1_008720 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3Cl)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M09 compound treatment 279.0 91.3 0.48 298.9 105.0 0.55 0.7228 0.9977 1974237 ChemDiv1_008721 COc1ccc(/C=C/2\SC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M10 compound treatment 286.1 98.4 0.51 310.1 116.0 0.6 0.7902 0.9967 1974238 ChemDiv1_008722 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M11 compound treatment 274.2 86.5 0.45 301.1 107.0 0.56 0.7132 0.9945 1974239 ChemDiv1_008723 CCCCC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)N4CCN(CC4)C(=O)C(CCCC)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M12 compound treatment 284.0 96.3 0.5 298.7 105.0 0.55 0.7405 0.9992 1414122 ChemDiv1_008724 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3Cl)C(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M13 compound treatment 277.8 90.1 0.47 296.9 103.0 0.54 0.711 0.9979 1442334 ChemDiv1_008725 OC(=O)CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5cccnc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M14 compound treatment 279.9 92.2 0.48 296.8 103.0 0.54 0.7184 0.9986 1350222 ChemDiv1_008726 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccnc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M15 compound treatment 276.3 88.6 0.46 293.1 99.3 0.52 0.6915 0.9985 1974240 ChemDiv1_008727 Clc1ccc(NC(=O)CSc2nnc(c3cccs3)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M16 compound treatment 279.6 91.9 0.48 296.3 102.0 0.53 0.7155 0.9986 1974241 ChemDiv1_008728 COc1ccccc1C2CC(=NN2C(=O)c3cccnc3)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M17 compound treatment 286.6 98.9 0.52 306.5 113.0 0.59 0.7788 0.998 1974242 ChemDiv1_008729 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5ccc(OC)cc45)[C@H]3C[C@@H]2[C@@H]1OC(=O)C)OC(=O)c6cc(OC)c(OC)c(OC)c6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M18 compound treatment 280.8 93.1 0.49 296.1 102.0 0.53 0.7192 0.999 1379242 ChemDiv1_008730 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5ccc(cc5)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M19 compound treatment 276.0 88.3 0.46 291.0 97.2 0.51 0.6827 0.9989 1134977 ChemDiv1_008731 Cc1cc2nnc(SCC(=O)c3ccc4OCOc4c3)n2c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M20 compound treatment 244.2 56.5 0.29 262.2 68.4 0.36 0.4596 0.9956 1974243 ChemDiv1_008732 Cc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)c(C)n1c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M21 compound treatment 280.6 92.9 0.48 289.6 95.8 0.5 0.6945 0.9999 1525329 ChemDiv1_008733 COc1ccc(cc1OC)C(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M22 compound treatment 275.5 87.8 0.46 289.6 95.8 0.5 0.6757 0.9991 1974244 ChemDiv1_008734 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(Br)ccc3O)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M23 mock treatment 282.5 94.8 0.49 287.1 93.3 0.48 0.6924 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 M24 mock treatment 198.0 10.3 0.05 195.1 1.28 0.01 0.0425 0.7889 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N01 compound treatment 287.2 99.5 0.52 300.6 107.0 0.56 0.7593 0.9994 1974245 ChemDiv1_008735 Cc1cc(/C=C/2\NC(=S)NC2=O)c(C)n1c3ccc(I)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N02 compound treatment 280.6 92.9 0.48 296.7 103.0 0.53 0.7206 0.9988 1492010 ChemDiv1_008736 Cc1nc2sc(C(=O)c3ccccc3)c(N)c2c(c4ccncc4)c1C(=O)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N03 compound treatment 280.3 92.6 0.48 296.6 103.0 0.53 0.7192 0.9987 1173169 ChemDiv1_008737 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC(=O)C)c3)c(=O)n2C1c4ccccc4OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N04 compound treatment 312.3 125.0 0.65 328.4 135.0 0.7 0.9541 0.9993 1724522 ChemDiv1_008738 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)cc3)c(=O)n2C1c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N05 compound treatment 345.3 158.0 0.82 356.6 163.0 0.85 1.1795 0.9999 1493768 ChemDiv1_008739 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N06 compound treatment 281.4 93.7 0.49 298.5 105.0 0.54 0.7302 0.9986 1974246 ChemDiv1_008740 CCOc1cc(/C=C/2\NC(=S)N(C2=O)c3ccc(OC)cc3)ccc1OCc4cccc(F)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N07 compound treatment 280.2 92.5 0.48 297.8 104.0 0.54 0.7232 0.9984 1974247 ChemDiv1_008741 Cc1nc(NC2=NC(CC(=O)N2)C(=O)Nc3ccc(Cl)cc3)nc4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N08 compound treatment 277.6 89.9 0.47 297.8 104.0 0.54 0.7136 0.9975 1369963 ChemDiv1_008742 CCCOc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N09 compound treatment 276.2 88.5 0.46 299.6 106.0 0.55 0.7151 0.9962 1974248 ChemDiv1_008743 Cc1ccc(C)c(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N10 compound treatment 275.7 88.0 0.46 295.4 102.0 0.53 0.6978 0.9976 1974249 ChemDiv1_008744 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OCCSCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N11 compound treatment 276.7 89.0 0.46 293.8 100.0 0.52 0.6956 0.9984 1974250 ChemDiv1_008745 Cc1cc(C)n2c(SCC(=O)O)nnc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N12 compound treatment 281.7 94.0 0.49 297.6 104.0 0.54 0.728 0.9989 1974251 ChemDiv1_008746 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N13 compound treatment 279.0 91.3 0.48 293.4 99.6 0.52 0.7026 0.9991 1974252 ChemDiv1_008747 COc1ccc(cc1)c2oc3ncn4nc(CSc5nc6ccccc6o5)nc4c3c2c7ccc(OC)cc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N14 compound treatment 275.3 87.6 0.46 296.9 103.0 0.54 0.7018 0.9968 1974253 ChemDiv1_008748 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N15 compound treatment 280.8 93.1 0.49 299.5 106.0 0.55 0.7317 0.9981 1974254 ChemDiv1_008749 CCOc1ccc(/N=C\2/S\C(=C/c3ccc(cc3)N(C)C)\C(=O)N2CC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N16 compound treatment 278.5 90.8 0.47 294.8 101.0 0.52 0.7059 0.9987 1598175 ChemDiv1_008750 CCOc1ccc(cc1)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N17 compound treatment 274.7 87.0 0.45 294.8 101.0 0.52 0.6919 0.9974 1281223 ChemDiv1_008751 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3ccc(cc3)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N18 compound treatment 282.9 95.2 0.5 299.5 106.0 0.55 0.7394 0.9987 1974255 ChemDiv1_008752 CCOC(=O)c1sc(NC(=O)CSC2=NCCS2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N19 compound treatment 276.6 88.9 0.46 291.1 97.3 0.51 0.6853 0.9991 1325983 ChemDiv1_008753 CCCSC1=C(C#N)C(C(=C(N1)c2ccccc2)C(=O)OCC)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N20 compound treatment 279.2 91.5 0.48 290.5 96.7 0.5 0.6927 0.9997 1152874 ChemDiv1_008754 O=C(Nc1nc2ccccc2n1Cc3ccccc3)C4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N21 compound treatment 283.5 95.8 0.5 296.7 103.0 0.53 0.7313 0.9994 1974256 ChemDiv1_008755 Nc1nc(SCC(=O)Nc2ccccc2)c(C#N)c(c1C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N22 compound treatment 276.6 88.9 0.46 283.2 89.4 0.46 0.6563 1.0 1974257 ChemDiv1_008756 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(SCC(=O)Nc4ccccc4)c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N23 mock treatment 279.6 91.9 0.48 286.3 92.5 0.48 0.6787 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 N24 mock treatment 196.1 8.35 0.04 190.2 -3.62 -0.02 0.0175 0.3687 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O01 compound treatment 282.1 94.4 0.49 298.9 105.0 0.55 0.7343 0.9987 1974258 ChemDiv1_008757 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5cccc(c5)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O02 compound treatment 283.1 95.4 0.5 294.0 100.0 0.52 0.7199 0.9997 1974259 ChemDiv1_008758 COc1ccc(cc1)c2csc3nc(SCC(=O)Nc4ccc5OCCOc5c4)n(CC=C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O03 compound treatment 281.8 94.1 0.49 297.2 103.0 0.54 0.7269 0.999 1597134 ChemDiv1_008759 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(s3)C(C)(C)C)C(=O)Nc4cccc(F)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O04 compound treatment 281.7 94.0 0.49 294.3 100.0 0.52 0.7159 0.9995 1974260 ChemDiv1_008760 CCOC(=O)c1c(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)sc5CCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O05 compound treatment 280.3 92.6 0.48 295.4 102.0 0.53 0.7148 0.999 1480676 ChemDiv1_008761 COc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O06 compound treatment 278.3 90.6 0.47 296.5 103.0 0.53 0.7114 0.9981 1436325 ChemDiv1_008762 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCCC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O07 compound treatment 279.1 91.4 0.48 291.3 97.5 0.51 0.6953 0.9995 1974261 ChemDiv1_008763 CCOC(=O)COc1ccc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O08 compound treatment 283.7 96.0 0.5 296.1 102.0 0.53 0.7299 0.9995 1616202 ChemDiv1_008764 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O09 compound treatment 277.9 90.2 0.47 297.6 104.0 0.54 0.714 0.9977 1974262 ChemDiv1_008765 COC(=O)c1ccc(/C=C/2\SC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O10 compound treatment 281.7 94.0 0.49 301.7 108.0 0.56 0.7431 0.9977 1974263 ChemDiv1_008766 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)c4ccc(Br)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O11 compound treatment 277.2 89.5 0.47 296.5 103.0 0.53 0.7074 0.9978 1663346 ChemDiv1_008767 Clc1ccccc1NC(=O)C2COc3ccccc3O2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O12 compound treatment 282.4 94.7 0.49 294.5 101.0 0.52 0.7192 0.9996 1361217 ChemDiv1_008768 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O13 compound treatment 272.7 85.0 0.44 300.1 106.0 0.55 0.704 0.994 1974264 ChemDiv1_008769 FC(F)(F)C(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O14 compound treatment 278.0 90.3 0.47 297.8 104.0 0.54 0.7151 0.9976 1216653 ChemDiv1_008770 COc1cccc(C2CC(=NN2C(=O)c3ccncc3)c4ccc(Br)cc4)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O15 compound treatment 279.2 91.5 0.48 293.4 99.6 0.52 0.7033 0.9992 1043054 ChemDiv1_008771 Cc1cc2nc(SCC(=O)O)[nH]c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O16 compound treatment 283.2 95.5 0.5 290.2 96.4 0.5 0.7063 1.0 1167123 ChemDiv1_008772 COc1ccc(C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O17 compound treatment 282.9 95.2 0.5 291.0 97.2 0.51 0.7082 1.0 1635492 ChemDiv1_008773 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(C(=O)C)c2nc(C)cc(C)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O18 compound treatment 276.9 89.2 0.47 293.2 99.4 0.52 0.6941 0.9986 1127058 ChemDiv1_008774 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O19 compound treatment 275.1 87.4 0.46 290.4 96.6 0.5 0.6772 0.9988 1974265 ChemDiv1_008775 O=C(CSc1ncnc2sc3CCCCc3c12)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O20 compound treatment 276.1 88.4 0.46 283.2 89.4 0.46 0.6544 1.0 1974266 ChemDiv1_008776 Cc1cccc(c1)N2C(=O)NC(=O)/C(=C/c3cn(CC(=O)Nc4ccccc4)c5ccccc35)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O21 compound treatment 278.8 91.1 0.47 289.3 95.5 0.5 0.6868 0.9998 1974267 ChemDiv1_008777 Clc1ccccc1c2csc3[nH]c(=S)n(CC=C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O22 compound treatment 280.6 92.9 0.48 288.9 95.1 0.49 0.692 0.9999 1974268 ChemDiv1_008778 COc1ccc(cc1)N2C(=O)/C(=C\c3ccc(Br)cc3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O23 mock treatment 282.3 94.6 0.49 287.1 93.3 0.48 0.6916 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 O24 mock treatment 108.0 -79.7 -0.42 87.5 -106.0 -0.55 -0.685 -0.9902 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P01 compound treatment 284.8 97.1 0.51 298.1 104.0 0.54 0.7413 0.9994 1974269 ChemDiv1_008779 Cc1cc(/C=C/2\NC(=O)NC2=O)c(C)n1c3ccc(F)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P02 compound treatment 287.7 100.0 0.52 292.2 98.4 0.51 0.7303 1.0 1137716 ChemDiv1_008780 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3cc4ccc(O)cc4oc3=O)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P03 compound treatment 288.5 101.0 0.53 302.8 109.0 0.57 0.7722 0.9993 1442438 ChemDiv1_008781 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccccc4OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P04 compound treatment 284.2 96.5 0.5 298.5 105.0 0.54 0.7405 0.9992 1492385 ChemDiv1_008782 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc(OC)c(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P05 compound treatment 291.6 104.0 0.54 306.7 113.0 0.59 0.798 0.9992 1375246 ChemDiv1_008783 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P06 compound treatment 280.8 93.1 0.49 296.9 103.0 0.54 0.7221 0.9988 1974270 ChemDiv1_008784 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P07 compound treatment 282.7 95.0 0.5 298.6 105.0 0.54 0.7354 0.9989 1974271 ChemDiv1_008785 Cc1ccc2c(C)nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccc(Br)cc4)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P08 compound treatment 279.8 92.1 0.48 296.6 103.0 0.53 0.7173 0.9986 1974272 ChemDiv1_008786 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P09 compound treatment 281.4 93.7 0.49 295.9 102.0 0.53 0.7207 0.9991 1974273 ChemDiv1_008787 Oc1ccccc1Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P10 compound treatment 277.8 90.1 0.47 297.7 104.0 0.54 0.714 0.9976 1974274 ChemDiv1_008788 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P11 compound treatment 280.5 92.8 0.48 292.1 98.3 0.51 0.7034 0.9996 1170150 ChemDiv1_008789 COc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(Br)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P12 compound treatment 278.4 90.7 0.47 296.6 103.0 0.53 0.7122 0.9981 1974275 ChemDiv1_008790 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)cc3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P13 compound treatment 278.3 90.6 0.47 295.1 101.0 0.53 0.7063 0.9985 1692815 ChemDiv1_008791 CC(NC(=O)c1ccccc1NC(=O)c2ccccc2)C(=O)N3CCN(C)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P14 compound treatment 279.2 91.5 0.48 294.6 101.0 0.52 0.7078 0.9989 1974276 ChemDiv1_008792 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P15 compound treatment 280.9 93.2 0.49 296.2 102.0 0.53 0.7199 0.999 1669883 ChemDiv1_008793 COc1cc(C)nc(NC(=O)Nc2sc(NS(=O)(=O)c3ccccc3)nc2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P16 compound treatment 281.5 93.8 0.49 295.5 102.0 0.53 0.7196 0.9992 1974277 ChemDiv1_008794 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P17 compound treatment 277.5 89.8 0.47 291.6 97.8 0.51 0.6905 0.9992 1385102 ChemDiv1_008795 Nc1c(sc2nc3CCCc3cc12)C(=O)Nc4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P18 compound treatment 283.4 95.7 0.5 294.2 100.0 0.52 0.7218 0.9998 1974278 ChemDiv1_008796 CCOC(=O)c1sc(NC(=O)CSc2nc(c3ccco3)c(C#N)c(=O)[nH]2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P19 compound treatment 280.1 92.4 0.48 287.7 93.9 0.49 0.6857 1.0 1710821 ChemDiv1_008797 CCOC(=O)C1=C(NC(=C(C#N)C1c2cccnc2)SCC(=O)OC)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P20 compound treatment 279.3 91.6 0.48 288.6 94.8 0.49 0.6861 0.9999 1251902 ChemDiv1_008798 Cc1ccc(Cn2c(NC(=O)C3CCCCC3)nc4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P21 compound treatment 281.7 94.0 0.49 291.5 97.7 0.51 0.7056 0.9998 1974279 ChemDiv1_008799 Nc1nc(SCC(=O)c2ccc3ccccc3c2)c(C#N)c(c1C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P22 compound treatment 281.3 93.6 0.49 290.6 96.8 0.5 0.7008 0.9999 1974280 ChemDiv1_008800 Cc1cc(C)nc(Sc2nnc(c3ccc(C)c(c3)S(=O)(=O)N4CCOCC4)c5ccccc25)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P23 mock treatment 281.0 93.3 0.49 288.1 94.3 0.49 0.6905 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.611 P24 mock treatment 94.8 -92.9 -0.48 99.0 -94.8 -0.49 -0.6914 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A01 compound treatment 284.5 96.8 0.5 295.9 103.0 0.54 0.7366 0.9995 1603828 ChemDiv1_008801 Cc1ccc(cc1S(=O)(=O)NCCO)c2nnc(Nc3cccc(Br)c3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A02 compound treatment 281.8 94.1 0.49 293.7 101.0 0.53 0.7186 0.9994 1974281 ChemDiv1_008802 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CSc2nc(C)nc3sc4CCCCc4c23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A03 compound treatment 284.2 96.5 0.5 290.7 98.1 0.51 0.7164 1.0 1974282 ChemDiv1_008803 CCOC(=O)CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(Br)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A04 compound treatment 280.7 93.0 0.49 296.9 104.0 0.54 0.7263 0.9985 1974283 ChemDiv1_008804 COC(=O)c1ccc(NC(=O)CSc2ncnc3sc4CCCc4c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A05 compound treatment 280.7 93.0 0.49 298.1 105.0 0.55 0.7307 0.9981 1389103 ChemDiv1_008805 Cc1ccc(cc1S(=O)(=O)Nn2cnnc2)c3n[nH]c(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A06 compound treatment 278.2 90.5 0.47 296.3 104.0 0.54 0.7149 0.9978 1184895 ChemDiv1_008806 COc1ccc(OC)c(NC(=O)c2ccc(cc2)N3C(=O)C4CC=C(C)CC4C3=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A07 compound treatment 280.6 92.9 0.48 298.6 106.0 0.55 0.7322 0.998 1257098 ChemDiv1_008807 Cc1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A08 compound treatment 277.8 90.1 0.47 295.0 102.0 0.53 0.7086 0.9981 1567285 ChemDiv1_008808 COc1ccc(OC)c(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A09 compound treatment 280.5 92.8 0.48 300.5 108.0 0.56 0.7388 0.9973 1504375 ChemDiv1_008809 COC(=O)c1cc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)cc(c1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A10 compound treatment 275.8 88.1 0.46 296.5 104.0 0.54 0.7068 0.9968 1974284 ChemDiv1_008810 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(F)cc3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A11 compound treatment 278.3 90.6 0.47 295.1 102.0 0.53 0.7108 0.9982 1721519 ChemDiv1_008811 Brc1cncc(c1)C(=O)Oc2ccc3c(=O)c(Oc4ccc5ccccc5c4)coc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A12 compound treatment 273.9 86.2 0.45 292.6 100.0 0.52 0.6854 0.9974 1210342 ChemDiv1_008812 CCOC(=O)Nc1c([nH]c2ccc(OC)cc12)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A13 compound treatment 278.6 90.9 0.47 291.8 99.2 0.52 0.6998 0.9991 1657821 ChemDiv1_008813 CC(=O)Nc1nc(C)c(s1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A14 compound treatment 276.1 88.4 0.46 293.0 100.0 0.52 0.695 0.9981 1974285 ChemDiv1_008814 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)CN3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A15 compound treatment 275.0 87.3 0.46 294.4 102.0 0.53 0.6961 0.9972 1974286 ChemDiv1_008815 Cc1sc2nc(SCC(=O)c3ccccc3F)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A16 compound treatment 278.0 90.3 0.47 290.6 98.0 0.51 0.6932 0.9992 1427808 ChemDiv1_008816 Cc1ccc(cc1)c2nnc(SCC(=O)n3c4CCCCc4c5ccccc35)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A17 compound treatment 277.1 89.4 0.47 291.2 98.6 0.51 0.6921 0.9989 1222056 ChemDiv1_008817 Cc1ccc(cc1)c2csc3ncnc(N4CCN(CC4)c5ccccn5)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A18 compound treatment 278.6 90.9 0.47 290.2 97.6 0.51 0.6939 0.9994 1655177 ChemDiv1_008818 COc1ccccc1NC(=O)CSCc2nc3ccccc3c(=O)n2c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A19 compound treatment 277.2 89.5 0.47 290.5 97.9 0.51 0.6899 0.9991 1974287 ChemDiv1_008819 C=CCn1c(SCC(=O)NCc2ccco2)nc3scc(c4ccccc4)c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A20 compound treatment 274.6 86.9 0.45 286.6 94.0 0.49 0.6659 0.9993 1308186 ChemDiv1_008820 CCC(=O)NCCN1CCN(CC1)C(=O)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A21 compound treatment 278.1 90.4 0.47 287.7 95.1 0.49 0.6829 0.9997 1974288 ChemDiv1_008821 COC(=O)c1c(NC(=O)CSc2ncnc3sc(C)c(C)c23)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A22 compound treatment 279.5 91.8 0.48 286.6 94.0 0.49 0.684 1.0 1974289 ChemDiv1_008822 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4cccc(c4)C(=O)O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A23 mock treatment 277.8 90.1 0.47 284.3 91.7 0.48 0.6693 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 A24 mock treatment 75.0 -113.0 -0.59 81.8 -111.0 -0.58 -0.8231 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B01 compound treatment 281.3 93.6 0.49 294.1 101.0 0.53 0.7182 0.9993 1258843 ChemDiv1_008823 COc1ccc(cc1)N2CCN(CC2)c3nc(nc(n3)N4CCCC4)N5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B02 compound treatment 280.9 93.2 0.49 291.9 99.3 0.52 0.7087 0.9996 1974290 ChemDiv1_008824 CCCCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B03 compound treatment 285.6 97.9 0.51 298.5 106.0 0.55 0.7503 0.9993 1320759 ChemDiv1_008825 CC1(C)CC(CCO1)n2c(SCC=C)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B04 compound treatment 283.1 95.4 0.5 296.5 104.0 0.54 0.7337 0.9992 1447745 ChemDiv1_008826 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(Cl)c4)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B05 compound treatment 278.2 90.5 0.47 298.3 106.0 0.55 0.7222 0.9972 1974291 ChemDiv1_008827 CC(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B06 compound treatment 278.7 91.0 0.47 293.5 101.0 0.52 0.7064 0.9988 1443479 ChemDiv1_008828 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B07 compound treatment 280.3 92.6 0.48 293.5 101.0 0.52 0.7123 0.9992 1974292 ChemDiv1_008829 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(cc5)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B08 compound treatment 275.9 88.2 0.46 296.7 104.0 0.54 0.7079 0.9968 1974293 ChemDiv1_008830 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B09 compound treatment 283.9 96.2 0.5 298.9 106.0 0.55 0.7454 0.9989 1974294 ChemDiv1_008831 Cc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B10 compound treatment 275.4 87.7 0.46 296.9 104.0 0.54 0.7067 0.9964 1974295 ChemDiv1_008832 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B11 compound treatment 284.0 96.3 0.5 294.4 102.0 0.53 0.7293 0.9997 1974296 ChemDiv1_008833 Cc1[nH]c2ncnn2c(=O)c1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B12 compound treatment 275.9 88.2 0.46 294.2 102.0 0.53 0.6987 0.9976 1485905 ChemDiv1_008834 CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B13 compound treatment 277.7 90.0 0.47 293.2 101.0 0.52 0.7016 0.9986 1468220 ChemDiv1_008835 Cc1cc(=O)n2nc(nc2[nH]1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B14 compound treatment 276.1 88.4 0.46 294.1 101.0 0.53 0.699 0.9978 1784308 ChemDiv1_008836 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(cc2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B15 compound treatment 275.5 87.8 0.46 291.5 98.9 0.51 0.6873 0.9983 1446401 ChemDiv1_008837 CCOC(=O)CSc1nnc2n(Cc3ccccc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B16 compound treatment 273.4 85.7 0.45 292.2 99.6 0.52 0.6821 0.9973 1494027 ChemDiv1_008838 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC5CCCC5)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B17 compound treatment 277.5 89.8 0.47 291.7 99.1 0.51 0.6954 0.9989 1974297 ChemDiv1_008839 COC(=O)C1=CN(CC2CCCO2)C=C(C1c3ccc(OCc4ccccc4)c(OC)c3)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B18 compound treatment 282.8 95.1 0.5 288.6 96.0 0.5 0.7035 1.0 1162463 ChemDiv1_008840 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5cccc(Cl)c5C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B19 compound treatment 277.5 89.8 0.47 289.7 97.1 0.5 0.688 0.9993 1493135 ChemDiv1_008841 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B20 compound treatment 272.6 84.9 0.44 287.4 94.8 0.49 0.6615 0.9986 1571017 ChemDiv1_008842 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4OC)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B21 compound treatment 276.3 88.6 0.46 286.3 93.7 0.49 0.6711 0.9997 1684478 ChemDiv1_008843 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B22 compound treatment 276.3 88.6 0.46 285.8 93.2 0.48 0.6693 0.9997 1529866 ChemDiv1_008844 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B23 mock treatment 280.3 92.6 0.48 286.5 93.9 0.49 0.6866 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 B24 mock treatment 74.6 -113.0 -0.59 81.1 -112.0 -0.58 -0.8271 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C01 compound treatment 285.0 97.3 0.51 294.0 101.0 0.53 0.7315 0.9998 1580089 ChemDiv1_008845 Cc1ccc(cc1S(=O)(=O)NC(C)(C)C)c2nnc(NCc3ccccc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C02 compound treatment 284.0 96.3 0.5 292.9 100.0 0.52 0.7238 0.9998 1974298 ChemDiv1_008846 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C03 compound treatment 278.6 90.9 0.47 296.5 104.0 0.54 0.7171 0.9979 1436418 ChemDiv1_008847 CNS(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C04 compound treatment 281.6 93.9 0.49 299.2 107.0 0.55 0.7381 0.9981 1334368 ChemDiv1_008848 C1CCN(CC1)c2nnc(N3CCCCC3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C05 compound treatment 281.0 93.3 0.49 295.6 103.0 0.54 0.7226 0.9989 1694632 ChemDiv1_008849 COc1ccc(Nc2nnc(C)c3ccccc23)cc1C(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C06 compound treatment 275.5 87.8 0.46 295.9 103.0 0.54 0.7034 0.9969 1451390 ChemDiv1_008850 COc1ccc(OC)c(NC(=O)c2cccc(c2)N3C(=O)C4CC=C(C)CC4C3=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C07 compound treatment 277.1 89.4 0.47 294.5 102.0 0.53 0.7042 0.998 1974299 ChemDiv1_008851 Clc1ccc(NC(=O)CSc2nnc3sc4ccccc4n23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C08 compound treatment 281.9 94.2 0.49 296.4 104.0 0.54 0.7289 0.9989 1237258 ChemDiv1_008852 COc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C09 compound treatment 276.3 88.6 0.46 295.6 103.0 0.54 0.7053 0.9973 1361952 ChemDiv1_008853 CCN1CCN(CC1)c2nnc(c3ccc(C)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C10 compound treatment 276.2 88.5 0.46 297.0 104.0 0.54 0.7101 0.9968 1154302 ChemDiv1_008854 COc1ccc(OC)c(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C11 compound treatment 278.1 90.4 0.47 294.9 102.0 0.53 0.7094 0.9982 1403131 ChemDiv1_008855 CC(=O)Nc1nc(C)c(s1)c2cn3cccnc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C12 compound treatment 279.3 91.6 0.48 289.6 97.0 0.5 0.6943 0.9996 1568535 ChemDiv1_008856 CC(=O)Nc1c([nH]c2ccc(F)cc12)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C13 compound treatment 276.2 88.5 0.46 294.0 101.0 0.53 0.699 0.9978 1438161 ChemDiv1_008857 COc1cc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4sc(NC(=O)C)nc4C)cc2)nc(OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C14 compound treatment 276.9 89.2 0.47 294.2 102.0 0.53 0.7024 0.998 1974300 ChemDiv1_008858 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)CN3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C15 compound treatment 279.2 91.5 0.48 293.3 101.0 0.52 0.7075 0.9989 1131260 ChemDiv1_008859 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc(cc3c1=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C16 compound treatment 271.9 84.2 0.44 294.8 102.0 0.53 0.6861 0.9955 1974301 ChemDiv1_008860 Cc1ccc2N(C(=O)CSc3nnc([nH]3)c4ccccc4)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C17 compound treatment 279.6 91.9 0.48 288.4 95.8 0.5 0.691 0.9998 1390131 ChemDiv1_008861 Cc1cc(NC(=O)CSc2nnc3cc(C)c4ccccc4n23)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C18 compound treatment 279.5 91.8 0.48 287.7 95.1 0.49 0.6881 0.9999 1485822 ChemDiv1_008862 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3C)oc4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C19 compound treatment 281.8 94.1 0.49 291.7 99.1 0.51 0.7112 0.9997 1974302 ChemDiv1_008863 Cc1nc(SCC(=O)c2ccc3OCOc3c2)c4c5CCCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C20 compound treatment 274.7 87.0 0.45 288.5 95.9 0.5 0.6733 0.9989 1974303 ChemDiv1_008864 COC(=O)c1ccc(CN2C(=O)C3CCCCC3C2=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C21 compound treatment 281.1 93.4 0.49 284.3 91.7 0.48 0.6815 0.9999 1974304 ChemDiv1_008865 Cc1sc2ncnc(SCC(=O)Nc3ccc4ccccc4c3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C22 compound treatment 279.9 92.2 0.48 291.9 99.3 0.52 0.705 0.9994 1974305 ChemDiv1_008866 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C23 mock treatment 277.0 89.3 0.47 286.0 93.4 0.49 0.6726 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 C24 mock treatment 78.5 -109.0 -0.57 82.5 -110.0 -0.57 -0.8076 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D01 compound treatment 285.6 97.9 0.51 296.3 104.0 0.54 0.7422 0.9996 1474016 ChemDiv1_008867 COc1ccc(cc1)N2CCN(CC2)c3nc(OC)nc(OC)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D02 compound treatment 281.5 93.8 0.49 296.6 104.0 0.54 0.7281 0.9988 1537496 ChemDiv1_008868 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D03 compound treatment 281.8 94.1 0.49 297.8 105.0 0.55 0.7337 0.9986 1388126 ChemDiv1_008869 CC1(C)CC(CCO1)n2c(SCC#C)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D04 compound treatment 282.2 94.5 0.49 298.5 106.0 0.55 0.7377 0.9985 1246706 ChemDiv1_008870 COC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D05 compound treatment 277.0 89.3 0.47 299.7 107.0 0.56 0.7229 0.9961 1974306 ChemDiv1_008871 CC(C)(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D06 compound treatment 286.5 98.8 0.52 298.3 106.0 0.55 0.7528 0.9995 1197235 ChemDiv1_008872 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D07 compound treatment 283.8 96.1 0.5 306.1 113.0 0.59 0.7715 0.9967 1381383 ChemDiv1_008873 CCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D08 compound treatment 277.7 90.0 0.47 299.8 107.0 0.56 0.7259 0.9964 1213683 ChemDiv1_008874 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D09 compound treatment 280.4 92.7 0.48 298.4 106.0 0.55 0.7307 0.998 1974307 ChemDiv1_008875 CCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D10 compound treatment 272.1 84.4 0.44 297.3 105.0 0.54 0.696 0.9945 1974308 ChemDiv1_008876 CCOc1cccc(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D11 compound treatment 274.0 86.3 0.45 294.3 102.0 0.53 0.692 0.9968 1265483 ChemDiv1_008877 O=C1CCC(=O)N1c2nc3NC(=CC(c4ccccc4)n3n2)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D12 compound treatment 276.1 88.4 0.46 296.1 103.0 0.54 0.7064 0.9971 1388952 ChemDiv1_008878 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D13 compound treatment 276.9 89.2 0.47 292.3 99.7 0.52 0.6954 0.9986 1974309 ChemDiv1_008879 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OCC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D14 compound treatment 277.1 89.4 0.47 293.8 101.0 0.53 0.7016 0.9982 1974310 ChemDiv1_008880 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(SC)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D15 compound treatment 271.5 83.8 0.44 293.1 100.0 0.52 0.6784 0.9961 1121338 ChemDiv1_008881 CCOC(=O)CSc1nnc2n(c3ccc(C)cc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D16 compound treatment 279.8 92.1 0.48 291.9 99.3 0.52 0.7046 0.9994 1138736 ChemDiv1_008882 COC(=O)C1=C(C)NC2=C(C1c3cccc(Cl)c3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D17 compound treatment 277.9 90.2 0.47 293.2 101.0 0.52 0.7024 0.9986 1454965 ChemDiv1_008883 COc1cccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D18 compound treatment 274.3 86.6 0.45 291.9 99.3 0.52 0.6843 0.9978 1527628 ChemDiv1_008884 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D19 compound treatment 274.9 87.2 0.45 288.9 96.3 0.5 0.6755 0.9989 1545540 ChemDiv1_008885 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D20 compound treatment 275.4 87.7 0.46 288.1 95.5 0.5 0.6744 0.9992 1447542 ChemDiv1_008886 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D21 compound treatment 279.4 91.7 0.48 290.4 97.8 0.51 0.6976 0.9995 1974311 ChemDiv1_008887 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D22 compound treatment 278.7 91.0 0.47 284.7 92.1 0.48 0.6741 1.0 1974312 ChemDiv1_008888 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D23 mock treatment 278.8 91.1 0.48 290.3 97.7 0.51 0.695 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 D24 mock treatment 77.5 -110.0 -0.57 83.1 -110.0 -0.57 -0.8091 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E01 compound treatment 286.1 98.4 0.51 299.1 106.0 0.55 0.7543 0.9993 1517462 ChemDiv1_008889 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3nnc(N4CCOCC4)c5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E02 compound treatment 282.6 94.9 0.5 295.9 103.0 0.54 0.7296 0.9992 1974313 ChemDiv1_008890 CCOC(=O)c1cc(NC(=O)CSc2nc(C)nc3sc4CCCCc4c23)cc(c1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E03 compound treatment 281.5 93.8 0.49 299.5 107.0 0.56 0.7388 0.998 1325606 ChemDiv1_008891 CN(C)S(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E04 compound treatment 280.9 93.2 0.49 293.4 101.0 0.52 0.7142 0.9993 1974314 ChemDiv1_008892 Fc1ccc(NC(=O)CSc2nnc3sc4ccccc4n23)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E05 compound treatment 279.4 91.7 0.48 300.3 108.0 0.56 0.734 0.9969 1283886 ChemDiv1_008893 COc1ccc(Nc2nnc(c3ccc(Cl)cc3)c4ccccc24)cc1C(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E06 compound treatment 281.6 93.9 0.49 298.2 106.0 0.55 0.7344 0.9984 1974315 ChemDiv1_008894 OCCNc1nc2nc(Cl)nc(N3CCCCC3)c2n1Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E07 compound treatment 280.1 92.4 0.48 299.3 107.0 0.55 0.7329 0.9976 1732405 ChemDiv1_008895 C=CCn1c(SCC(=O)Nc2ccccc2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E08 compound treatment 278.1 90.4 0.47 296.6 104.0 0.54 0.7156 0.9977 1167325 ChemDiv1_008896 COc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E09 compound treatment 275.8 88.1 0.46 297.5 105.0 0.55 0.7104 0.9964 1306447 ChemDiv1_008897 C=CCn1c(SCC(=O)NCc2ccc3OCOc3c2)nc4sc5CCCCc5c4c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E10 compound treatment 278.5 90.8 0.47 296.6 104.0 0.54 0.7171 0.9978 1974316 ChemDiv1_008898 O=C(OCCN1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)c4cccc5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E11 compound treatment 276.3 88.6 0.46 296.4 104.0 0.54 0.7082 0.997 1360756 ChemDiv1_008899 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccncc4)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E12 compound treatment 278.2 90.5 0.47 299.9 107.0 0.56 0.7281 0.9966 1412577 ChemDiv1_008900 COc1ccc2[nH]c(C(=O)O)c(NC(=O)C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E13 compound treatment 274.3 86.6 0.45 296.6 104.0 0.54 0.7016 0.996 1308483 ChemDiv1_008901 CC(=O)Nc1nc(C)c(s1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4cc(C)on4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E14 compound treatment 274.4 86.7 0.45 293.4 101.0 0.52 0.6902 0.9973 1785277 ChemDiv1_008902 Cc1ccnc2c(NC(=O)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O)cccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E15 compound treatment 275.4 87.7 0.46 295.8 103.0 0.54 0.7027 0.9969 1974317 ChemDiv1_008903 COC(=O)c1sc(NC(=O)CSc2ncnc3sc4CCCCc4c23)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E16 compound treatment 275.2 87.5 0.46 293.7 101.0 0.53 0.6942 0.9975 1974318 ChemDiv1_008904 COc1ccc2N(C(=O)CSc3nnc([nH]3)c4ccc(C)cc4)C(C)(C)c5ssc(=S)c5-c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E17 compound treatment 280.0 92.3 0.48 294.5 102.0 0.53 0.7149 0.9989 1974319 ChemDiv1_008905 FC(F)(F)c1cc(NC(=O)CSc2nnc3sc4ccccc4n23)ccc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E18 compound treatment 275.0 87.3 0.46 293.2 101.0 0.52 0.6917 0.9976 1974320 ChemDiv1_008906 [O-][N+](=O)c1ccc2C(=O)N(Cc3ccccc3)S(=O)(=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E19 compound treatment 280.3 92.6 0.48 292.2 99.6 0.52 0.7075 0.9994 1974321 ChemDiv1_008907 COc1ccc(CCNC(=O)CSc2nc(C)nc3sc4CCCCc4c23)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E20 compound treatment 280.1 92.4 0.48 288.1 95.5 0.5 0.6917 0.9999 1974322 ChemDiv1_008908 O=C(Nc1nccs1)c2ccc(cc2)N3C(=O)C4CCCCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E21 compound treatment 274.7 87.0 0.45 291.7 99.1 0.51 0.685 0.998 1974323 ChemDiv1_008909 CCOC(=O)c1ccc(NC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E22 compound treatment 277.7 90.0 0.47 284.8 92.2 0.48 0.6708 0.9999 1974324 ChemDiv1_008910 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(cc3)C(=O)OC)/N(CC)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E23 mock treatment 281.0 93.3 0.49 288.9 96.3 0.5 0.698 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 E24 mock treatment 79.9 -108.0 -0.56 82.6 -110.0 -0.57 -0.8021 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F01 compound treatment 289.7 102.0 0.53 298.5 106.0 0.55 0.7654 0.9999 1592543 ChemDiv1_008911 O=c1cccc2C3CC(CN(C3)c4nc(nc(n4)N5CCOCC5)N6CCOCC6)Cn21 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F02 compound treatment 281.9 94.2 0.49 295.7 103.0 0.54 0.7263 0.9991 1396412 ChemDiv1_008912 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F03 compound treatment 277.8 90.1 0.47 294.5 102.0 0.53 0.7068 0.9982 1673438 ChemDiv1_008913 CC1(C)CC(CCO1)n2c(SCC#C)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F04 compound treatment 280.4 92.7 0.48 295.3 103.0 0.53 0.7193 0.9988 1974325 ChemDiv1_008914 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F05 compound treatment 283.5 95.8 0.5 305.9 113.0 0.59 0.7697 0.9967 1303981 ChemDiv1_008915 CCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F06 compound treatment 280.0 92.3 0.48 299.7 107.0 0.56 0.734 0.9974 1974326 ChemDiv1_008916 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F07 compound treatment 285.2 97.5 0.51 304.6 112.0 0.58 0.7712 0.9977 1974327 ChemDiv1_008917 CCCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F08 compound treatment 280.3 92.6 0.48 298.6 106.0 0.55 0.7311 0.9979 1974328 ChemDiv1_008918 COC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F09 compound treatment 272.3 84.6 0.44 298.3 106.0 0.55 0.7005 0.9941 1974329 ChemDiv1_008919 CC(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F10 compound treatment 280.2 92.5 0.48 297.4 105.0 0.54 0.7263 0.9982 1459868 ChemDiv1_008920 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F11 compound treatment 281.5 93.8 0.49 297.7 105.0 0.55 0.7322 0.9985 1974330 ChemDiv1_008921 Cc1[nH]c2nc(CC(=O)O)nn2c(=O)c1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F12 compound treatment 278.1 90.4 0.47 296.8 104.0 0.54 0.7163 0.9976 1352426 ChemDiv1_008922 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccc(C)c(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F13 compound treatment 276.4 88.7 0.46 294.3 102.0 0.53 0.7009 0.9978 1974331 ChemDiv1_008923 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1Oc4nc(Cl)ncc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F14 compound treatment 274.8 87.1 0.45 297.3 105.0 0.54 0.706 0.996 1784309 ChemDiv1_008924 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F15 compound treatment 274.2 86.5 0.45 295.5 103.0 0.53 0.6972 0.9964 1464671 ChemDiv1_008925 Cc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SCC(=O)N)nnc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F16 compound treatment 277.3 89.6 0.47 296.3 104.0 0.54 0.7115 0.9975 1974332 ChemDiv1_008926 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F17 compound treatment 275.4 87.7 0.46 289.8 97.2 0.51 0.6806 0.9988 1974333 ChemDiv1_008927 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F18 compound treatment 280.8 93.1 0.49 294.5 102.0 0.53 0.7178 0.9991 1391480 ChemDiv1_008928 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F19 compound treatment 278.8 91.1 0.48 292.0 99.4 0.52 0.7013 0.9991 1974334 ChemDiv1_008929 CCCCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F20 compound treatment 274.2 86.5 0.45 291.8 99.2 0.52 0.6836 0.9978 1974335 ChemDiv1_008930 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F21 compound treatment 274.8 87.1 0.45 284.9 92.3 0.48 0.6604 0.9996 1470801 ChemDiv1_008931 CCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F22 compound treatment 273.6 85.9 0.45 285.4 92.8 0.48 0.6578 0.9993 1673586 ChemDiv1_008932 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F23 mock treatment 279.5 91.8 0.48 284.6 92.0 0.48 0.6767 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 F24 mock treatment 79.5 -108.0 -0.56 78.9 -114.0 -0.59 -0.8171 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G01 compound treatment 288.3 101.0 0.52 300.8 108.0 0.56 0.7687 0.9994 1729656 ChemDiv1_008933 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3nnc(NCc4nc5ccccc5[nH]4)c6ccccc36 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G02 compound treatment 280.2 92.5 0.48 294.6 102.0 0.53 0.716 0.9989 1974336 ChemDiv1_008934 CCOC(=O)c1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)cc(c1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G03 compound treatment 280.4 92.7 0.48 296.8 104.0 0.54 0.7248 0.9984 1604732 ChemDiv1_008935 CCN(CC)S(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G04 compound treatment 284.3 96.6 0.5 302.5 110.0 0.57 0.7602 0.9981 1974337 ChemDiv1_008936 COC(=O)c1c(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)sc5CCCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G05 compound treatment 279.6 91.9 0.48 296.4 104.0 0.54 0.7204 0.9983 1974338 ChemDiv1_008937 CCOC(=O)CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(OC)c(c3)C(=O)N)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G06 compound treatment 277.7 90.0 0.47 298.2 106.0 0.55 0.72 0.997 1974339 ChemDiv1_008938 CCCCNc1nc(Cl)nc2nc(NCCO)n(Cc3ccccc3)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G07 compound treatment 277.5 89.8 0.47 299.1 106.0 0.55 0.7226 0.9966 1974340 ChemDiv1_008939 O=C(CSc1nnc2sc3ccccc3n12)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G08 compound treatment 277.8 90.1 0.47 298.4 106.0 0.55 0.7211 0.997 1974341 ChemDiv1_008940 COc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G09 compound treatment 279.7 92.0 0.48 296.6 104.0 0.54 0.7215 0.9982 1974342 ChemDiv1_008941 COC(=O)c1c(NC(=O)CSc2nnc3cc(C)c4ccccc4n23)sc5CC(C)CCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G10 compound treatment 281.7 94.0 0.49 298.2 106.0 0.55 0.7348 0.9984 1494119 ChemDiv1_008942 COc1cc(cc(OC)c1OC)C(=O)Nc2cccc(c2)c3nc4cc(Cl)cc(Cl)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G11 compound treatment 280.0 92.3 0.48 298.0 105.0 0.55 0.7278 0.9979 1305833 ChemDiv1_008943 Cc1nc2ccccn2c1c3csc(Nc4ccc(cc4)S(=O)(=O)Nc5nc(C)cc(C)n5)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G12 compound treatment 276.8 89.1 0.46 297.7 105.0 0.55 0.7148 0.9968 1974343 ChemDiv1_008944 COC(=O)c1[nH]c2ccccc2c1NC(=O)CN(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G13 compound treatment 276.0 88.3 0.46 294.6 102.0 0.53 0.7005 0.9976 1974344 ChemDiv1_008945 O=C(CSc1ncnc2sc(cc12)c3ccccc3)Nc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G14 compound treatment 274.8 87.1 0.45 295.5 103.0 0.53 0.6994 0.9967 1513371 ChemDiv1_008946 Cc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(NCCN)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G15 compound treatment 270.9 83.2 0.43 295.4 103.0 0.53 0.6846 0.9947 1974345 ChemDiv1_008947 CC1CCc2c(C#N)c(NC(=O)CSc3nnc4cc(C)c5ccccc5n34)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G16 compound treatment 275.6 87.9 0.46 297.7 105.0 0.55 0.7104 0.9962 1974346 ChemDiv1_008948 CC1=CC(C)(C)N(C(=O)CSc2nnc(o2)c3ccc(C)cc3)c4ccc(C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G17 compound treatment 275.6 87.9 0.46 298.9 106.0 0.55 0.7148 0.9957 1974347 ChemDiv1_008949 O=C(CSc1nnc2sc3ccccc3n12)Nc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G18 compound treatment 274.6 86.9 0.45 293.4 101.0 0.52 0.6909 0.9974 1180942 ChemDiv1_008950 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc5CCCCCc5cc4c3N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G19 compound treatment 278.4 90.7 0.47 288.7 96.1 0.5 0.6877 0.9996 1974348 ChemDiv1_008951 COC(=O)c1cc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)cc(c1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G20 compound treatment 278.3 90.6 0.47 292.1 99.5 0.52 0.6998 0.999 1407727 ChemDiv1_008952 Oc1ccccc1NC(=O)CC2SC(=O)NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G21 compound treatment 276.6 88.9 0.46 290.2 97.6 0.51 0.6865 0.999 1974349 ChemDiv1_008953 CCOC(=O)c1c(NC(=O)CSc2ncnc3sc(C)c(C)c23)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G22 compound treatment 278.1 90.4 0.47 287.4 94.8 0.49 0.6818 0.9998 1974350 ChemDiv1_008954 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)C(=O)O)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G23 mock treatment 277.2 89.5 0.47 288.8 96.2 0.5 0.6836 0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 G24 mock treatment 78.2 -110.0 -0.57 82.2 -110.0 -0.57 -0.8098 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H01 compound treatment 283.6 95.9 0.5 297.2 105.0 0.54 0.7381 0.9991 1442227 ChemDiv1_008955 O=c1cccc2C3CC(CN(C3)c4nc(nc(n4)N5CCCC5)N6CCCC6)Cn21 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H02 compound treatment 282.7 95.0 0.5 295.4 103.0 0.53 0.7282 0.9993 1974351 ChemDiv1_008956 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H03 compound treatment 281.7 94.0 0.49 300.7 108.0 0.56 0.744 0.9977 1541496 ChemDiv1_008957 Sc1nnc(o1)C2OCCc3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H04 compound treatment 281.3 93.6 0.49 296.1 103.0 0.54 0.7256 0.9988 1784297 ChemDiv1_008958 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H05 compound treatment 287.6 99.9 0.52 302.9 110.0 0.57 0.7738 0.9989 1166831 ChemDiv1_008959 CC(C)Oc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H06 compound treatment 284.5 96.8 0.5 300.8 108.0 0.56 0.7546 0.9986 1784298 ChemDiv1_008960 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(cc4)[N+](=O)[O-])C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H07 compound treatment 285.6 97.9 0.51 307.3 115.0 0.6 0.7826 0.997 1974352 ChemDiv1_008961 CCCCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H08 compound treatment 276.1 88.4 0.46 300.8 108.0 0.56 0.7237 0.9952 1360491 ChemDiv1_008962 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H09 compound treatment 274.9 87.2 0.45 302.7 110.0 0.57 0.7262 0.9935 1974353 ChemDiv1_008963 CCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H10 compound treatment 280.9 93.2 0.49 301.2 109.0 0.56 0.7428 0.9972 1784303 ChemDiv1_008964 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(c4)[N+](=O)[O-])C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H11 compound treatment 277.6 89.9 0.47 299.8 107.0 0.56 0.7255 0.9963 1974354 ChemDiv1_008965 Cc1cc(=O)n2nc(CC(=O)O)nc2[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H12 compound treatment 274.2 86.5 0.45 300.5 108.0 0.56 0.7156 0.9942 1784306 ChemDiv1_008966 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H13 compound treatment 273.6 85.9 0.45 294.4 102.0 0.53 0.6909 0.9966 1933370 ChemDiv1_008967 COC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)cc3[N+](=O)[O-])c(=O)n2C1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H14 compound treatment 280.4 92.7 0.48 301.0 108.0 0.56 0.7403 0.9971 1784310 ChemDiv1_008968 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(cc2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H15 compound treatment 279.3 91.6 0.48 299.0 106.0 0.55 0.7288 0.9974 1974355 ChemDiv1_008969 NC(=O)CSc1nnc2n(Cc3ccccc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H16 compound treatment 277.3 89.6 0.47 297.5 105.0 0.55 0.716 0.9971 1640947 ChemDiv1_008970 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(SC)cc4)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H17 compound treatment 273.1 85.4 0.45 297.2 105.0 0.54 0.6994 0.9951 1974356 ChemDiv1_008971 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H18 compound treatment 280.7 93.0 0.49 290.0 97.4 0.51 0.7009 0.9998 1317287 ChemDiv1_008972 COC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H19 compound treatment 278.3 90.6 0.47 289.1 96.5 0.5 0.6888 0.9996 1974357 ChemDiv1_008973 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(Cl)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H20 compound treatment 276.3 88.6 0.46 293.3 101.0 0.52 0.6968 0.9981 1124648 ChemDiv1_008974 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H21 compound treatment 277.8 90.1 0.47 291.7 99.1 0.51 0.6965 0.999 1348545 ChemDiv1_008975 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H22 compound treatment 278.6 90.9 0.47 285.9 93.3 0.48 0.6781 0.9999 1778458 ChemDiv1_008976 O=C(CCN1C(=O)c2ccccc2C1=O)N3CCN(C/C=C/c4ccccc4)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H23 mock treatment 278.7 91.0 0.47 285.9 93.3 0.48 0.6785 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 H24 mock treatment 77.4 -110.0 -0.58 84.1 -109.0 -0.56 -0.8058 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I01 compound treatment 281.8 94.1 0.49 297.4 105.0 0.54 0.7322 0.9987 1609524 ChemDiv1_008977 Cc1nnc(Nc2ccc(OCC(=O)N)cc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I02 compound treatment 284.6 96.9 0.51 296.5 104.0 0.54 0.7392 0.9995 1974358 ChemDiv1_008978 Cc1nc(SCCN2C(=O)c3ccccc3C2=O)c4c5CCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I03 compound treatment 281.5 93.8 0.49 298.2 106.0 0.55 0.734 0.9984 1157122 ChemDiv1_008979 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3n[nH]c(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I04 compound treatment 283.8 96.1 0.5 295.7 103.0 0.54 0.7333 0.9994 1974359 ChemDiv1_008980 COC(=O)c1ccc(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I05 compound treatment 278.5 90.8 0.47 298.6 106.0 0.55 0.7244 0.9972 1571686 ChemDiv1_008981 Cc1ccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I06 compound treatment 287.4 99.7 0.52 303.1 110.0 0.57 0.7738 0.9988 1974360 ChemDiv1_008982 CCOC(=O)c1ccc(cc1)n2c(/C=C/c3ccc(o3)[N+](=O)[O-])nc4ccccc4c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I07 compound treatment 279.5 91.8 0.48 298.7 106.0 0.55 0.7285 0.9975 1559560 ChemDiv1_008983 Fc1ccccc1NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I08 compound treatment 278.1 90.4 0.47 302.8 110.0 0.57 0.7384 0.9953 1639467 ChemDiv1_008984 COc1ccc(CNC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I09 compound treatment 281.2 93.5 0.49 301.6 109.0 0.57 0.7454 0.9972 1974361 ChemDiv1_008985 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc5CC(C)CCc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I10 compound treatment 278.8 91.1 0.48 298.7 106.0 0.55 0.7259 0.9973 1734531 ChemDiv1_008986 Clc1cc(Cl)c2oc(nc2c1)c3cccc(NC(=O)c4ccc5OCCOc5c4)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I11 compound treatment 274.2 86.5 0.45 295.4 103.0 0.53 0.6968 0.9965 1401343 ChemDiv1_008987 Cc1nc2sccn2c1c3csc(Nc4ccc(cc4)S(=O)(=O)Nc5nc(C)cc(C)n5)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I12 compound treatment 278.4 90.7 0.47 298.5 106.0 0.55 0.7237 0.9972 1974362 ChemDiv1_008988 COC(=O)c1[nH]c2ccc(C)cc2c1NC(=O)CN3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I13 compound treatment 274.8 87.1 0.45 293.3 101.0 0.52 0.6913 0.9975 1974363 ChemDiv1_008989 CC1CCc2c(C#N)c(NC(=O)CSc3nnc4ccccn34)sc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I14 compound treatment 274.8 87.1 0.45 301.3 109.0 0.56 0.7207 0.9942 1974364 ChemDiv1_008990 CN(C)c1nc(Oc2ccc(OCCOc3ccccc3)nn2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I15 compound treatment 273.2 85.5 0.45 295.5 103.0 0.53 0.6935 0.9959 1974365 ChemDiv1_008991 Cc1sc2ncnc(SCC(=O)Nc3sc(cc3C(=O)N)c4ccccc4)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I16 compound treatment 276.3 88.6 0.46 294.0 101.0 0.53 0.6994 0.9979 1940370 ChemDiv1_008992 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2cccc(c2)[N+](=O)[O-])SCC(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I17 compound treatment 277.0 89.3 0.47 296.3 104.0 0.54 0.7104 0.9974 1138332 ChemDiv1_008993 C=CCn1c(SCC(=O)NCCc2ccccc2)nc3sc4CCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I18 compound treatment 278.7 91.0 0.47 293.2 101.0 0.52 0.7053 0.9988 1597670 ChemDiv1_008994 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3cccc4cccnc34)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I19 compound treatment 278.9 91.2 0.48 290.5 97.9 0.51 0.6961 0.9994 1974366 ChemDiv1_008995 Cc1cc(C(=O)CSc2nnc3sc4ccccc4n23)c(C)n1c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I20 compound treatment 273.7 86.0 0.45 291.8 99.2 0.52 0.6817 0.9976 1381341 ChemDiv1_008996 O=C(CC1SC(=O)NC1=O)NCc2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I21 compound treatment 278.0 90.3 0.47 288.2 95.6 0.5 0.6844 0.9996 1974367 ChemDiv1_008997 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2ncnc3sc(C)c(C)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I22 compound treatment 276.5 88.8 0.46 291.2 98.6 0.51 0.6899 0.9987 1974368 ChemDiv1_008998 O=C(Nc1ccc2C(=O)c3ccccc3C(=O)c2c1)C(c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I23 mock treatment 275.5 87.8 0.46 287.9 95.3 0.5 0.674 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 I24 mock treatment 76.2 -112.0 -0.58 84.1 -109.0 -0.56 -0.8102 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J01 compound treatment 284.7 97.0 0.51 291.1 98.5 0.51 0.7197 1.0 1609010 ChemDiv1_008999 Clc1nc(NCC=C)nc(n1)N2CC3CC(C2)c4cccc(=O)n4C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J02 compound treatment 283.3 95.6 0.5 293.4 101.0 0.52 0.723 0.9997 1360319 ChemDiv1_009000 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(OC)c4OC)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J03 compound treatment 276.7 89.0 0.46 297.5 105.0 0.55 0.7137 0.9968 1683593 ChemDiv1_009001 COc1cc2CCN(C(C)c2cc1OC)C(=O)C3COc4ccccc4O3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J04 compound treatment 281.5 93.8 0.49 299.7 107.0 0.56 0.7395 0.9979 1974369 ChemDiv1_009002 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J05 compound treatment 280.3 92.6 0.48 296.3 104.0 0.54 0.7226 0.9985 1291091 ChemDiv1_009003 COc1ccc(cc1OC)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J06 compound treatment 281.9 94.2 0.49 295.3 103.0 0.53 0.7248 0.9992 1974370 ChemDiv1_009004 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(Cl)c3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J07 compound treatment 289.5 102.0 0.53 302.2 110.0 0.57 0.7782 0.9994 1974371 ChemDiv1_009005 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J08 compound treatment 280.1 92.4 0.48 296.9 104.0 0.54 0.7241 0.9983 1974372 ChemDiv1_009006 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3F)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J09 compound treatment 276.4 88.7 0.46 299.2 107.0 0.55 0.7189 0.996 1974373 ChemDiv1_009007 CCCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J10 compound treatment 279.3 91.6 0.48 297.5 105.0 0.55 0.7233 0.9978 1974374 ChemDiv1_009008 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J11 compound treatment 277.6 89.9 0.47 300.9 108.0 0.56 0.7296 0.9959 1974375 ChemDiv1_009009 Cc1cc(=O)n2nc(nc2[nH]1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J12 compound treatment 278.0 90.3 0.47 302.9 110.0 0.57 0.7384 0.9953 1784307 ChemDiv1_009010 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(cc4)[N+](=O)[O-])C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J13 compound treatment 273.8 86.1 0.45 300.1 107.0 0.56 0.7126 0.9941 1158319 ChemDiv1_009011 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J14 compound treatment 274.2 86.5 0.45 295.2 103.0 0.53 0.6961 0.9966 1378736 ChemDiv1_009012 COC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J15 compound treatment 275.6 87.9 0.46 298.1 105.0 0.55 0.7119 0.9961 1376622 ChemDiv1_009013 CC1=C(C(NC(=O)N1)c2cc3OCOc3cc2Br)C(=O)OC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J16 compound treatment 275.6 87.9 0.46 295.6 103.0 0.54 0.7027 0.997 1372700 ChemDiv1_009014 CCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J17 compound treatment 282.1 94.4 0.49 296.6 104.0 0.54 0.7304 0.9989 1699694 ChemDiv1_009015 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J18 compound treatment 278.2 90.5 0.47 290.9 98.3 0.51 0.695 0.9992 1568931 ChemDiv1_009016 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J19 compound treatment 276.8 89.1 0.46 288.0 95.4 0.5 0.6792 0.9995 1523405 ChemDiv1_009017 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(OC)c(OC)c4)C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J20 compound treatment 276.5 88.8 0.46 289.5 96.9 0.5 0.6836 0.9991 1703446 ChemDiv1_009018 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(SC)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J21 compound treatment 274.1 86.4 0.45 287.8 95.2 0.49 0.6685 0.9989 1974376 ChemDiv1_009019 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J22 compound treatment 277.5 89.8 0.47 290.2 97.6 0.51 0.6899 0.9992 1575119 ChemDiv1_009020 Clc1ccc(CN2CCN(CC2)C(=O)CCN3C(=O)c4ccccc4C3=O)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J23 mock treatment 276.9 89.2 0.47 286.8 94.2 0.49 0.6752 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 J24 mock treatment 78.3 -109.0 -0.57 83.4 -109.0 -0.57 -0.805 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K01 compound treatment 282.8 95.1 0.5 299.0 106.0 0.55 0.7418 0.9985 1512847 ChemDiv1_009021 NC(=O)COc1ccc(Nc2nnc(c3ccc(Cl)cc3)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K02 compound treatment 283.8 96.1 0.5 292.2 99.6 0.52 0.7205 0.9999 1974377 ChemDiv1_009022 Cc1nc(SCC(=O)c2ccc3OCCOc3c2)c4c5CCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K03 compound treatment 283.2 95.5 0.5 297.5 105.0 0.55 0.7377 0.999 1368040 ChemDiv1_009023 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3n[nH]c(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K04 compound treatment 282.5 94.8 0.49 296.0 103.0 0.54 0.7296 0.9991 1535329 ChemDiv1_009024 CC(=O)Nc1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K05 compound treatment 278.5 90.8 0.47 294.8 102.0 0.53 0.7105 0.9984 1974378 ChemDiv1_009025 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)/C=C/c3cccc4ccccc34)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K06 compound treatment 284.6 96.9 0.51 300.4 108.0 0.56 0.7535 0.9987 1974379 ChemDiv1_009026 [O-][N+](=O)c1ccc(/C=C/c2nc3ccccc3c(=O)n2c4ccc(Br)cc4)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K07 compound treatment 282.2 94.5 0.49 300.8 108.0 0.56 0.7462 0.9978 1974380 ChemDiv1_009027 COC(=O)c1cc(NC(=O)CSc2ncnc3sc4CCCc4c23)cc(c1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K08 compound treatment 280.6 92.9 0.48 300.1 107.0 0.56 0.7377 0.9975 1371338 ChemDiv1_009028 O=C(NCCN1CCOCC1)c2cc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K09 compound treatment 283.2 95.5 0.5 302.1 109.0 0.57 0.7546 0.9978 1974381 ChemDiv1_009029 Cc1nc(SCC(=O)Nc2sc3CCCc3c2C(=O)N)c4c5CCCc5sc4n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K10 compound treatment 274.0 86.3 0.45 297.6 105.0 0.55 0.7042 0.9954 1214189 ChemDiv1_009030 COc1cc(OC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K11 compound treatment 278.5 90.8 0.47 295.3 103.0 0.53 0.7123 0.9982 1152745 ChemDiv1_009031 Cc1nc2ncccn2c1c3csc(Nc4ccc(cc4)S(=O)(=O)Nc5nc(C)cc(C)n5)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K12 compound treatment 277.1 89.4 0.47 297.3 105.0 0.54 0.7145 0.9971 1974382 ChemDiv1_009032 CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)CN(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K13 compound treatment 277.3 89.6 0.47 297.8 105.0 0.55 0.7171 0.997 1974383 ChemDiv1_009033 Cc1sc2ncnc(SCC(=O)NC3(CC4CC5CC(C4)C3)C5)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K14 compound treatment 276.3 88.6 0.46 298.8 106.0 0.55 0.717 0.9961 1740484 ChemDiv1_009034 CN(C)c1nc(Oc2ccc(OCC=C)nn2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K15 compound treatment 275.4 87.7 0.46 291.9 99.3 0.52 0.6884 0.9982 1974384 ChemDiv1_009035 Fc1ccc(cc1)c2csc3nc(SCC(=O)NCc4ccc5OCOc5c4)n(CC=C)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K16 compound treatment 280.3 92.6 0.48 297.5 105.0 0.55 0.727 0.9982 1341469 ChemDiv1_009036 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2)SC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K17 compound treatment 279.3 91.6 0.48 291.7 99.1 0.51 0.702 0.9993 1974385 ChemDiv1_009037 COC(=O)c1cc(NC(=O)CSc2nc3scc(c4ccccc4)c3c(=O)n2CC=C)cc(c1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K18 compound treatment 276.2 88.5 0.46 294.2 102.0 0.53 0.6998 0.9978 1500032 ChemDiv1_009038 COC(=O)CN1C(=O)C2(C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K19 compound treatment 273.3 85.6 0.45 296.0 103.0 0.54 0.6957 0.9958 1974386 ChemDiv1_009039 COC(=O)c1sc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K20 compound treatment 275.8 88.1 0.46 293.2 101.0 0.52 0.6946 0.9979 1655384 ChemDiv1_009040 O=C(CC1SC(=O)N(CN2CCOCC2)C1=O)NCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K21 compound treatment 277.4 89.7 0.47 291.6 99.0 0.51 0.6946 0.9989 1974387 ChemDiv1_009041 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nnc3ccccn23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K22 compound treatment 277.2 89.5 0.47 284.1 91.5 0.48 0.6663 1.0 1974388 ChemDiv1_009042 Cc1cc(OCC(=O)Nc2ccc3C(=O)c4ccccc4C(=O)c3c2)cc(C)c1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K23 mock treatment 277.6 89.9 0.47 289.9 97.3 0.51 0.6891 0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 K24 mock treatment 80.9 -107.0 -0.56 84.9 -108.0 -0.56 -0.7899 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L01 compound treatment 283.7 96.0 0.5 296.6 104.0 0.54 0.7363 0.9993 1547570 ChemDiv1_009043 CCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L02 compound treatment 281.1 93.4 0.49 292.7 100.0 0.52 0.7123 0.9995 1784296 ChemDiv1_009044 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L03 compound treatment 281.6 93.9 0.49 294.4 102.0 0.53 0.7204 0.9993 1974389 ChemDiv1_009045 COc1ccc(N/C(=C\2/C(=NN(C2=O)c3ccccc3)C)/c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L04 compound treatment 280.0 92.3 0.48 296.6 104.0 0.54 0.7226 0.9983 1441398 ChemDiv1_009046 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L05 compound treatment 287.1 99.4 0.52 301.6 109.0 0.57 0.7672 0.999 1974390 ChemDiv1_009047 Brc1ccc2OC(N3N=C(CC3c2c1)c4ccccc4)c5ccc(OCc6ccccc6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L06 compound treatment 278.0 90.3 0.47 295.2 103.0 0.53 0.7101 0.9981 1339189 ChemDiv1_009048 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4OC)C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L07 compound treatment 281.0 93.3 0.49 293.4 101.0 0.52 0.7145 0.9993 1974391 ChemDiv1_009049 CC(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L08 compound treatment 277.4 89.7 0.47 299.3 107.0 0.55 0.7229 0.9964 1784300 ChemDiv1_009050 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L09 compound treatment 278.2 90.5 0.47 299.8 107.0 0.56 0.7277 0.9966 1974392 ChemDiv1_009051 Cc1[nH]c2ncnn2c(=O)c1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L10 compound treatment 276.9 89.2 0.47 297.7 105.0 0.55 0.7152 0.9968 1559816 ChemDiv1_009052 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC(C)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L11 compound treatment 280.9 93.2 0.49 295.1 102.0 0.53 0.7204 0.999 1129234 ChemDiv1_009053 COC(=O)c1nc2[nH]c(C)cc(=O)n2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L12 compound treatment 272.8 85.1 0.44 294.8 102.0 0.53 0.6894 0.996 1525353 ChemDiv1_009054 COC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)cc3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L13 compound treatment 275.5 87.8 0.46 297.7 105.0 0.55 0.7101 0.9962 1268235 ChemDiv1_009055 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CC(=C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L14 compound treatment 279.1 91.4 0.48 292.7 100.0 0.52 0.705 0.9991 1784311 ChemDiv1_009056 CCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L15 compound treatment 277.7 90.0 0.47 295.2 103.0 0.53 0.709 0.998 1479913 ChemDiv1_009057 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OC5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L16 compound treatment 279.1 91.4 0.48 295.8 103.0 0.54 0.7163 0.9983 1974393 ChemDiv1_009058 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L17 compound treatment 273.9 86.2 0.45 296.2 104.0 0.54 0.6986 0.996 1384951 ChemDiv1_009059 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L18 compound treatment 278.7 91.0 0.47 292.5 99.9 0.52 0.7027 0.999 1784314 ChemDiv1_009060 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L19 compound treatment 280.6 92.9 0.48 290.6 98.0 0.51 0.7028 0.9997 1784295 ChemDiv1_009061 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L20 compound treatment 276.2 88.5 0.46 295.5 103.0 0.53 0.7045 0.9973 1974394 ChemDiv1_009062 CCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L21 compound treatment 278.2 90.5 0.47 289.1 96.5 0.5 0.6884 0.9995 1416416 ChemDiv1_009063 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L22 compound treatment 271.8 84.1 0.44 284.6 92.0 0.48 0.6483 0.9991 1596703 ChemDiv1_009064 CN(C)C(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L23 mock treatment 282.2 94.5 0.49 284.2 91.6 0.48 0.6851 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 L24 mock treatment 76.0 -112.0 -0.58 83.0 -110.0 -0.57 -0.815 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M01 compound treatment 287.1 99.4 0.52 296.2 104.0 0.54 0.7473 0.9998 1463851 ChemDiv1_009065 CNC(=O)COc1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)NC(C)C)c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M02 compound treatment 280.7 93.0 0.49 291.1 98.5 0.51 0.705 0.9996 1392303 ChemDiv1_009066 COC(=O)c1c(C)[nH]c(C(=O)CSc2nc(C)nc3sc4CCCc4c23)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M03 compound treatment 277.4 89.7 0.47 291.7 99.1 0.51 0.695 0.9989 1721115 ChemDiv1_009067 CC(C)NS(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M04 compound treatment 281.3 93.6 0.49 296.3 104.0 0.54 0.7263 0.9988 1974395 ChemDiv1_009068 COC(=O)c1sc(NC(=O)CSc2ncnc3sc4CCCc4c23)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M05 compound treatment 276.4 88.7 0.46 296.6 104.0 0.54 0.7093 0.997 1390522 ChemDiv1_009069 CCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(C)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M06 compound treatment 279.4 91.7 0.48 294.0 101.0 0.53 0.7108 0.9988 1723377 ChemDiv1_009070 CCCCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccccc2Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M07 compound treatment 279.7 92.0 0.48 295.5 103.0 0.53 0.7175 0.9985 1319057 ChemDiv1_009071 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nc(C)nc3sc4CCCc4c23)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M08 compound treatment 281.0 93.3 0.49 295.6 103.0 0.54 0.7226 0.9989 1738083 ChemDiv1_009072 Clc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)nc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M09 compound treatment 276.3 88.6 0.46 297.2 105.0 0.54 0.7112 0.9967 1177071 ChemDiv1_009073 C=CCn1c(SCC(=O)NCc2ccc3OCOc3c2)nc4sc5CCCc5c4c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M10 compound treatment 278.8 91.1 0.48 296.6 104.0 0.54 0.7182 0.9979 1210198 ChemDiv1_009074 CCOC(=O)c1[nH]c2ccc(F)cc2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M11 compound treatment 282.6 94.9 0.5 301.0 108.0 0.56 0.7484 0.9979 1662182 ChemDiv1_009075 Cc1nc(N)sc1c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M12 compound treatment 281.4 93.7 0.49 289.7 97.1 0.5 0.7024 0.9999 1974396 ChemDiv1_009076 CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)CN3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M13 compound treatment 278.5 90.8 0.47 296.6 104.0 0.54 0.7171 0.9978 1390009 ChemDiv1_009077 Cc1sc2nc(SCc3ccc4OCOc4c3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M14 compound treatment 274.1 86.4 0.45 293.7 101.0 0.53 0.6902 0.9971 1325589 ChemDiv1_009078 CN(C)c1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M15 compound treatment 281.1 93.4 0.49 292.6 100.0 0.52 0.712 0.9995 1974397 ChemDiv1_009079 O=C(CSc1ncnc2sc3CCCc3c12)NCc4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M16 compound treatment 278.9 91.2 0.48 290.2 97.6 0.51 0.695 0.9995 1974398 ChemDiv1_009080 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Cl)cc2C=c3sc4nc5ccccc5n4c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M17 compound treatment 279.2 91.5 0.48 293.8 101.0 0.53 0.7094 0.9988 1552735 ChemDiv1_009081 C=CCn1c(SCC(=O)Nc2ccc3OCOc3c2)nc4sc5CCCc5c4c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M18 compound treatment 278.3 90.6 0.47 292.5 99.9 0.52 0.7013 0.9989 1675759 ChemDiv1_009082 CC(=C)CSc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M19 compound treatment 277.9 90.2 0.47 288.5 95.9 0.5 0.6851 0.9996 1974399 ChemDiv1_009083 COC(=O)c1sc(NC(=O)CSc2nnc3cc(C)c4ccccc4n23)c(C(=O)OC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M20 compound treatment 276.0 88.3 0.46 289.6 97.0 0.5 0.6821 0.999 1974400 ChemDiv1_009084 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=NN(C3=O)c4ccc(C)c(Cl)c4)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M21 compound treatment 274.0 86.3 0.45 285.4 92.8 0.48 0.6593 0.9994 1974401 ChemDiv1_009085 FC(F)(F)c1ccccc1NC(=O)CSc2ncnc3sc4CCCc4c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M22 compound treatment 282.0 94.3 0.49 287.1 94.5 0.49 0.6951 1.0 1974402 ChemDiv1_009086 Brc1ccc(OCC(=O)Nc2ccc3C(=O)c4ccccc4C(=O)c3c2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M23 mock treatment 276.9 89.2 0.47 290.1 97.5 0.51 0.6873 0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 M24 mock treatment 212.9 25.2 0.13 191.5 -1.13 -0.01 0.0888 0.6748 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N01 compound treatment 282.8 95.1 0.5 294.2 102.0 0.53 0.7241 0.9995 1297789 ChemDiv1_009087 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N02 compound treatment 283.3 95.6 0.5 292.0 99.4 0.52 0.7179 0.9998 1278880 ChemDiv1_009088 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4Cl)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N03 compound treatment 281.5 93.8 0.49 291.3 98.7 0.51 0.7087 0.9997 1974403 ChemDiv1_009089 CC/1=NN(C(=O)\C1=C(/Nc2cccc(C)c2)\c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N04 compound treatment 277.8 90.1 0.47 292.5 99.9 0.52 0.6994 0.9988 1488693 ChemDiv1_009090 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N05 compound treatment 279.8 92.1 0.48 290.6 98.0 0.51 0.6998 0.9996 1974404 ChemDiv1_009091 CCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N06 compound treatment 279.9 92.2 0.48 293.7 101.0 0.53 0.7116 0.999 1498868 ChemDiv1_009092 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N07 compound treatment 280.2 92.5 0.48 298.6 106.0 0.55 0.7307 0.9978 1974405 ChemDiv1_009093 Cc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(cc5)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N08 compound treatment 281.7 94.0 0.49 293.4 101.0 0.52 0.7171 0.9995 1974406 ChemDiv1_009094 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)c(Cl)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N09 compound treatment 278.3 90.6 0.47 290.4 97.8 0.51 0.6936 0.9993 1974407 ChemDiv1_009095 COC(=O)c1nc2[nH]c(C)c([N+](=O)[O-])c(=O)n2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N10 compound treatment 276.4 88.7 0.46 294.2 102.0 0.53 0.7005 0.9978 1311379 ChemDiv1_009096 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cc(C)ccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N11 compound treatment 278.0 90.3 0.47 296.9 104.0 0.54 0.7163 0.9976 1974408 ChemDiv1_009097 CCOC(=O)c1nc2[nH]c(C)cc(=O)n2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N12 compound treatment 280.6 92.9 0.48 290.5 97.9 0.51 0.7024 0.9997 1141481 ChemDiv1_009098 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N13 compound treatment 278.5 90.8 0.47 293.6 101.0 0.52 0.7061 0.9987 1282501 ChemDiv1_009099 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N14 compound treatment 278.4 90.7 0.47 291.2 98.6 0.51 0.6969 0.9992 1148133 ChemDiv1_009100 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N15 compound treatment 277.1 89.4 0.47 290.8 98.2 0.51 0.6906 0.999 1974409 ChemDiv1_009101 COC(=O)C1=CN(CC2CCCO2)C=C(C1c3ccc(OC)c(OCc4ccccc4)c3)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N16 compound treatment 276.0 88.3 0.46 295.6 103.0 0.54 0.7042 0.9972 1650518 ChemDiv1_009102 COC(=O)C1=C(C)NC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N17 compound treatment 277.9 90.2 0.47 291.8 99.2 0.52 0.6972 0.999 1974410 ChemDiv1_009103 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)cc3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N18 compound treatment 277.3 89.6 0.47 290.6 98.0 0.51 0.6906 0.9991 1784315 ChemDiv1_009104 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(c4)[N+](=O)[O-])C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N19 compound treatment 278.3 90.6 0.47 288.7 96.1 0.5 0.6873 0.9996 1181180 ChemDiv1_009105 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N20 compound treatment 277.2 89.5 0.47 284.0 91.4 0.47 0.666 1.0 1284579 ChemDiv1_009106 CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N21 compound treatment 276.5 88.8 0.46 285.8 93.2 0.48 0.67 0.9998 1974411 ChemDiv1_009107 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N22 compound treatment 277.0 89.3 0.47 286.8 94.2 0.49 0.6755 0.9997 1974412 ChemDiv1_009108 CN(C)C(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N23 mock treatment 278.3 90.6 0.47 284.9 92.3 0.48 0.6733 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 N24 mock treatment 197.3 9.6 0.05 189.8 -2.83 -0.01 0.025 0.479 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O01 compound treatment 285.5 97.8 0.51 291.0 98.4 0.51 0.7223 1.0 1974413 ChemDiv1_009109 CCOC(=O)CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3cccc(Br)c3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O02 compound treatment 283.7 96.0 0.5 291.5 98.9 0.51 0.7175 0.9999 1974414 ChemDiv1_009110 O=C(CSc1ncnc2sc3CCCc3c12)CC(=O)Nc4sc5CCCCc5c4C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O03 compound treatment 282.4 94.7 0.49 294.7 102.0 0.53 0.7245 0.9994 1376162 ChemDiv1_009111 Cc1ccc(cc1S(=O)(=O)NC(C)(C)C)c2n[nH]c(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O04 compound treatment 286.2 98.5 0.51 293.5 101.0 0.52 0.7341 0.9999 1974415 ChemDiv1_009112 O=C(CSc1ncnc2sc3CCCCc3c12)Nc4sccc4C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O05 compound treatment 280.4 92.7 0.48 291.8 99.2 0.52 0.7064 0.9995 1974416 ChemDiv1_009113 Cc1sc2nc(SCC(=O)Nc3ccc(C)cc3)n(CC=C)c(=O)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O06 compound treatment 277.1 89.4 0.47 290.6 98.0 0.51 0.6899 0.999 1692259 ChemDiv1_009114 Cc1cc(NCCN)nc(NS(=O)(=O)c2ccccc2Cl)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O07 compound treatment 279.5 91.8 0.48 290.9 98.3 0.51 0.6998 0.9995 1691550 ChemDiv1_009115 CN1CCN(CC1)c2nnc(c3ccc(C)c(C)c3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O08 compound treatment 280.8 93.1 0.49 292.3 99.7 0.52 0.7098 0.9995 1930239 ChemDiv1_009116 COc1cc(ccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O09 compound treatment 282.1 94.4 0.49 298.6 106.0 0.55 0.7377 0.9984 1974417 ChemDiv1_009117 CC(C)c1ccc(/C=C(\C#N)/C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O10 compound treatment 279.2 91.5 0.48 291.7 99.1 0.51 0.7016 0.9993 1629180 ChemDiv1_009118 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O11 compound treatment 276.7 89.0 0.46 294.5 102.0 0.53 0.7027 0.9979 1270995 ChemDiv1_009119 Cc1nc(C)c(s1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O12 compound treatment 276.1 88.4 0.46 291.5 98.9 0.51 0.6895 0.9985 1974418 ChemDiv1_009120 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)CN(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O13 compound treatment 279.0 91.3 0.48 293.6 101.0 0.52 0.7079 0.9988 1974419 ChemDiv1_009121 CCOC(=O)c1c(C)c(sc1NC(=O)CSc2nc(C)nc3sc4CCCc4c23)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O14 compound treatment 275.3 87.6 0.46 293.3 101.0 0.52 0.6931 0.9977 1427171 ChemDiv1_009122 CC(C)OC(=O)c1sc2nc(N3CCOCC3)c4COC(C)(C)Cc4c2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O15 compound treatment 280.0 92.3 0.48 295.6 103.0 0.54 0.7189 0.9986 1974420 ChemDiv1_009123 C=CCn1c(SCC(=O)NCc2ccc3OCOc3c2)nc4scc(c5ccccc5)c4c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O16 compound treatment 274.4 86.7 0.45 287.7 95.1 0.49 0.6692 0.999 1974421 ChemDiv1_009124 OC1(C(=O)N2c3c1cccc3Sc4ccccc24)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O17 compound treatment 279.0 91.3 0.48 289.9 97.3 0.51 0.6943 0.9996 1216842 ChemDiv1_009125 COC(=O)c1c(C)[nH]c(C(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O18 compound treatment 279.1 91.4 0.48 290.2 97.6 0.51 0.6958 0.9995 1974422 ChemDiv1_009126 CCOCCSc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O19 compound treatment 276.6 88.9 0.46 284.7 92.1 0.48 0.6663 0.9999 1974423 ChemDiv1_009127 COC(=O)c1c(NC(=O)CSc2ncnc3sc(C)c(C)c23)sc4CCCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O20 compound treatment 279.1 91.4 0.48 289.0 96.4 0.5 0.6914 0.9997 1974424 ChemDiv1_009128 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=NN(C3=O)c4ccc(Cl)c(c4)C(=O)O)C)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O21 compound treatment 277.7 90.0 0.47 288.7 96.1 0.5 0.6851 0.9995 1516804 ChemDiv1_009129 COC(=O)c1c(C)[nH]c(C(=O)CSc2ncnc3sc4CCCc4c23)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O22 compound treatment 274.8 87.1 0.45 283.6 91.0 0.47 0.6556 0.9998 1690227 ChemDiv1_009130 COc1ccc(cc1)N2CCN(CC2)c3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O23 mock treatment 278.5 90.8 0.47 283.7 91.1 0.47 0.6697 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 O24 mock treatment 94.8 -92.9 -0.48 97.8 -94.8 -0.49 -0.6912 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P01 compound treatment 288.1 100.0 0.52 292.9 100.0 0.52 0.7389 1.0 1974425 ChemDiv1_009131 CCCCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C5CCOC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P02 compound treatment 282.0 94.3 0.49 290.3 97.7 0.51 0.7068 0.9999 1718407 ChemDiv1_009132 COC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P03 compound treatment 285.5 97.8 0.51 289.4 96.8 0.5 0.7164 1.0 1974426 ChemDiv1_009133 CC1=NN(C(=O)c2ccccc2Br)C(O)(C1)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P04 compound treatment 284.0 96.3 0.5 291.7 99.1 0.51 0.7194 0.9999 1974427 ChemDiv1_009134 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(C)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P05 compound treatment 285.5 97.8 0.51 291.1 98.5 0.51 0.7227 1.0 1974428 ChemDiv1_009135 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(cc5)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P06 compound treatment 279.5 91.8 0.48 294.3 102.0 0.53 0.7123 0.9988 1616758 ChemDiv1_009136 COC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)c(Cl)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P07 compound treatment 280.8 93.1 0.49 293.0 100.0 0.52 0.7123 0.9994 1369310 ChemDiv1_009137 COc1ccc(cc1OC)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P08 compound treatment 282.3 94.6 0.49 292.4 99.8 0.52 0.7157 0.9997 1784301 ChemDiv1_009138 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P09 compound treatment 284.6 96.9 0.51 295.1 102.0 0.53 0.7341 0.9997 1974429 ChemDiv1_009139 CCOC(=O)Cc1nc2[nH]c(C)c([N+](=O)[O-])c(=O)n2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P10 compound treatment 283.6 95.9 0.5 295.5 103.0 0.53 0.7318 0.9994 1468687 ChemDiv1_009140 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(SC)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P11 compound treatment 281.6 93.9 0.49 294.6 102.0 0.53 0.7212 0.9992 1974430 ChemDiv1_009141 CCOC(=O)Cc1nc2[nH]c(C)cc(=O)n2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P12 compound treatment 277.3 89.6 0.47 294.2 102.0 0.53 0.7038 0.9982 1559230 ChemDiv1_009142 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cccc(Cl)c3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P13 compound treatment 277.2 89.5 0.47 293.5 101.0 0.52 0.7009 0.9983 1528958 ChemDiv1_009143 COc1ccccc1n2c(SCC(=O)N)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P14 compound treatment 279.1 91.4 0.48 293.4 101.0 0.52 0.7075 0.9989 1119971 ChemDiv1_009144 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4OC(C)C)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P15 compound treatment 286.3 98.6 0.51 289.1 96.5 0.5 0.7183 0.9999 1479435 ChemDiv1_009145 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P16 compound treatment 279.8 92.1 0.48 295.8 103.0 0.54 0.7189 0.9985 1672402 ChemDiv1_009146 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P17 compound treatment 281.0 93.3 0.49 294.6 102.0 0.53 0.7189 0.9991 1784294 ChemDiv1_009147 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P18 compound treatment 277.3 89.6 0.47 287.6 95.0 0.49 0.6796 0.9996 1318406 ChemDiv1_009148 CCOc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P19 compound treatment 276.8 89.1 0.46 289.9 97.3 0.51 0.6862 0.9991 1199977 ChemDiv1_009149 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(OC)c4OC)C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P20 compound treatment 276.9 89.2 0.47 288.6 96.0 0.5 0.6818 0.9994 1376915 ChemDiv1_009150 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P21 compound treatment 278.3 90.6 0.47 287.7 95.1 0.49 0.6836 0.9998 1128673 ChemDiv1_009151 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P22 compound treatment 273.7 86.0 0.45 285.4 92.8 0.48 0.6582 0.9993 1567848 ChemDiv1_009152 CC(=O)Oc1ccc(C2Nc3ccc4ccccc4c3C5C=CCC52)c(OC(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P23 mock treatment 283.0 95.3 0.5 289.7 97.1 0.5 0.7083 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.612 P24 mock treatment 110.2 -77.5 -0.4 100.9 -91.7 -0.48 -0.623 -0.9966 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A01 compound treatment 285.7 99.4 0.52 294.8 103.0 0.54 0.7451 0.9999 1719174 ChemDiv1_009153 CN(C)C(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A02 compound treatment 281.4 95.1 0.5 289.2 97.4 0.51 0.7086 1.0 1974431 ChemDiv1_009154 CN1CCN(CC1)C(=O)/C(=C\c2cccnc2)/NC(=O)c3ccco3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A03 compound treatment 281.9 95.6 0.5 292.5 101.0 0.52 0.7226 0.9997 1160549 ChemDiv1_009155 COC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccccc4O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A04 compound treatment 279.9 93.6 0.49 289.8 98.0 0.51 0.7053 0.9998 1974432 ChemDiv1_009156 COc1ccccc1N2CCN(CC2)C(=O)/C(=C/c3ccccc3)/NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A05 compound treatment 280.0 93.7 0.49 292.0 100.0 0.52 0.7138 0.9995 1210424 ChemDiv1_009157 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A06 compound treatment 282.0 95.7 0.5 294.4 103.0 0.53 0.73 0.9995 1974433 ChemDiv1_009158 Cc1ccc(o1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A07 compound treatment 279.1 92.8 0.48 290.6 98.8 0.51 0.7053 0.9996 1974434 ChemDiv1_009159 COc1ccc2oc(C(=O)C)c(N)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A08 compound treatment 279.5 93.2 0.49 297.3 105.0 0.55 0.7314 0.9982 1974435 ChemDiv1_009160 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A09 compound treatment 280.8 94.5 0.49 299.8 108.0 0.56 0.7454 0.9979 1974436 ChemDiv1_009161 CCOC(=O)c1c(CN(C(=O)CN2CCCCC2)c3ccccc3)n(c4ccccc4)c5cc(Br)c(OC)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A10 compound treatment 275.3 89.0 0.46 293.9 102.0 0.53 0.7034 0.9978 1121736 ChemDiv1_009162 COc1cc(cc(Br)c1O)C2CC(=O)NC(=C2C#N)SCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A11 compound treatment 277.7 91.4 0.48 292.9 101.0 0.53 0.7086 0.9988 1232969 ChemDiv1_009163 COC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc4CC(C)CCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A12 compound treatment 275.8 89.5 0.47 297.1 105.0 0.55 0.717 0.9969 1974437 ChemDiv1_009164 CC(=O)c1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A13 compound treatment 276.9 90.6 0.47 292.9 101.0 0.53 0.7056 0.9986 1377105 ChemDiv1_009165 CCOC(=O)Cc1nnc(NC(=O)CSc2nnc3c4ccccc4n(CC=C)c3n2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A14 compound treatment 276.9 90.6 0.47 287.4 95.6 0.5 0.6854 0.9997 1974438 ChemDiv1_009166 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A15 compound treatment 278.1 91.8 0.48 292.9 101.0 0.53 0.7101 0.9989 1974439 ChemDiv1_009167 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccc(C)cc3nc2N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A16 compound treatment 279.7 93.4 0.49 294.0 102.0 0.53 0.72 0.9991 1241290 ChemDiv1_009168 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2CC)C#N)c3ccccc3OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A17 compound treatment 278.6 92.3 0.48 289.7 97.9 0.51 0.7002 0.9996 1717377 ChemDiv1_009169 CNC(=O)N(C)c1nnc(o1)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A18 compound treatment 277.2 90.9 0.47 289.1 97.3 0.51 0.6928 0.9995 1974440 ChemDiv1_009170 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A19 compound treatment 277.1 90.8 0.47 286.4 94.6 0.49 0.6825 0.9998 1192805 ChemDiv1_009171 Cc1nc2ncnc(c3ccccc3)c2n1c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A20 compound treatment 276.6 90.3 0.47 285.7 93.9 0.49 0.6781 0.9998 1492604 ChemDiv1_009172 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A21 compound treatment 279.1 92.8 0.48 286.0 94.2 0.49 0.6884 1.0 1974441 ChemDiv1_009173 COc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A22 compound treatment 274.4 88.1 0.46 282.5 90.7 0.47 0.6582 0.9999 1544308 ChemDiv1_009174 Cc1cccc(C)c1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A23 mock treatment 277.4 91.1 0.48 284.9 93.1 0.48 0.6781 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 A24 mock treatment 75.9 -110.0 -0.58 82.4 -109.0 -0.57 -0.8095 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B01 compound treatment 286.6 100.0 0.52 290.9 99.1 0.51 0.7341 1.0 1974442 ChemDiv1_009175 COc1ccc(cc1)C/2=NN(C(=O)\C2=C/c3ccc(OC)c(O)c3)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B02 compound treatment 284.4 98.1 0.51 294.4 103.0 0.53 0.7388 0.9998 1430173 ChemDiv1_009176 CCN(CC)c1cc(C)nc(NCc2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B03 compound treatment 285.7 99.4 0.52 292.6 101.0 0.52 0.737 1.0 1974443 ChemDiv1_009177 COc1cccc(C2C(=C(N)Oc3[nH]nc(C)c23)C#N)c1OCc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B04 compound treatment 282.3 96.0 0.5 291.9 100.0 0.52 0.7219 0.9998 1389532 ChemDiv1_009178 COC(=O)CSc1nnc2n(C3CCCCC3)c(=O)c4c5CCCCc5sc4n12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B05 compound treatment 280.7 94.4 0.49 296.6 105.0 0.54 0.7333 0.9987 1974444 ChemDiv1_009179 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4F)C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B06 compound treatment 280.8 94.5 0.49 292.5 101.0 0.52 0.7186 0.9996 1974445 ChemDiv1_009180 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B07 compound treatment 277.2 90.9 0.47 293.3 101.0 0.53 0.7082 0.9986 1974446 ChemDiv1_009181 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B08 compound treatment 273.8 87.5 0.46 292.2 100.0 0.52 0.6916 0.9978 1974447 ChemDiv1_009182 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B09 compound treatment 278.6 92.3 0.48 292.8 101.0 0.52 0.7115 0.9991 1974448 ChemDiv1_009183 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cc(C)ccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B10 compound treatment 276.4 90.1 0.47 288.3 96.5 0.5 0.6869 0.9995 1281703 ChemDiv1_009184 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B11 compound treatment 277.3 91.0 0.47 291.6 99.8 0.52 0.7023 0.999 1703653 ChemDiv1_009185 CC(C(=O)c1ccccc1)C2(O)C(=O)N(Cc3ccccc3C)c4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B12 compound treatment 278.6 92.3 0.48 295.2 103.0 0.54 0.7204 0.9985 1250498 ChemDiv1_009186 COc1cccc(c1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B13 compound treatment 274.5 88.2 0.46 289.4 97.6 0.51 0.6839 0.9988 1974449 ChemDiv1_009187 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B14 compound treatment 274.6 88.3 0.46 290.4 98.6 0.51 0.688 0.9986 1519435 ChemDiv1_009188 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B15 compound treatment 274.5 88.2 0.46 291.1 99.3 0.52 0.6902 0.9984 1871204 ChemDiv1_009189 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccccc5c4=O)C(=O)OCC6CCCO6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B16 compound treatment 275.8 89.5 0.47 290.2 98.4 0.51 0.6917 0.999 1180617 ChemDiv1_009190 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(Br)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B17 compound treatment 276.9 90.6 0.47 291.3 99.5 0.52 0.6998 0.999 1974450 ChemDiv1_009191 CCOCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B18 compound treatment 278.9 92.6 0.48 289.9 98.1 0.51 0.702 0.9996 1941557 ChemDiv1_009192 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B19 compound treatment 273.1 86.8 0.45 287.1 95.3 0.5 0.6703 0.999 1871375 ChemDiv1_009193 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(O)c(c3)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B20 compound treatment 274.7 88.4 0.46 285.5 93.7 0.49 0.6703 0.9996 1533763 ChemDiv1_009194 COc1cccc(C2NC(=O)NC(=C2C(=O)Nc3ccccc3Cl)C)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B21 compound treatment 276.9 90.6 0.47 284.6 92.8 0.48 0.6751 0.9999 1974451 ChemDiv1_009195 OCCCn1c(/C=C/c2cn(Cc3ccccc3)c4ccccc24)nc5ccccc5c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B22 compound treatment 276.5 90.2 0.47 281.9 90.1 0.47 0.6637 1.0 1974452 ChemDiv1_009196 COCCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(C)c4ccccc34)c(=O)n2C1c5ccc(OC(=O)c6ccco6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B23 mock treatment 276.8 90.5 0.47 284.8 93.0 0.48 0.6755 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 B24 mock treatment 77.0 -109.0 -0.57 83.6 -108.0 -0.56 -0.801 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C01 compound treatment 279.1 92.8 0.48 295.6 104.0 0.54 0.7237 0.9985 1176544 ChemDiv1_009197 Oc1ccccc1c2nc(NCCc3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C02 compound treatment 277.3 91.0 0.47 292.7 101.0 0.52 0.7064 0.9988 1974453 ChemDiv1_009198 COc1ccc(/C=C(/NC(=O)c2cccc(C)c2)\C(=O)NCCc3c[nH]c4ccccc34)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C03 compound treatment 278.8 92.5 0.48 291.0 99.2 0.52 0.7057 0.9995 1974454 ChemDiv1_009199 FC(F)(F)c1cc(nc(n1)N2CCOCC2)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C04 compound treatment 283.5 97.2 0.51 296.3 104.0 0.54 0.7425 0.9994 1974455 ChemDiv1_009200 Cc1ccc(/C=C(/NC(=O)c2ccccc2)\C(=O)NCCc3c[nH]c4ccccc34)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C05 compound treatment 276.9 90.6 0.47 298.0 106.0 0.55 0.7244 0.997 1332750 ChemDiv1_009201 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C06 compound treatment 279.2 92.9 0.48 294.8 103.0 0.54 0.7211 0.9988 1200050 ChemDiv1_009202 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C07 compound treatment 278.2 91.9 0.48 298.1 106.0 0.55 0.7296 0.9975 1597231 ChemDiv1_009203 COc1ccc2occ(C(=O)c3oc4ccc(Cl)cc4c3N)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C08 compound treatment 278.7 92.4 0.48 293.7 102.0 0.53 0.7152 0.9989 1974456 ChemDiv1_009204 Cc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C09 compound treatment 277.0 90.7 0.47 296.1 104.0 0.54 0.7178 0.9977 1500182 ChemDiv1_009205 COC(=O)c1oc2ccc(Cl)cc2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C10 compound treatment 277.4 91.1 0.48 293.5 102.0 0.53 0.7097 0.9986 1974457 ChemDiv1_009206 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C11 compound treatment 281.5 95.2 0.5 294.8 103.0 0.54 0.7296 0.9993 1140405 ChemDiv1_009207 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CCCN3C(=O)c4ccccc4C3=O)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C12 compound treatment 280.0 93.7 0.49 288.4 96.6 0.5 0.7005 0.9999 1199486 ChemDiv1_009208 CCc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OC)c3ccccc3Cl)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C13 compound treatment 285.0 98.7 0.51 301.4 110.0 0.57 0.7668 0.9987 1974458 ChemDiv1_009209 Oc1ccc(Cl)cc1C2=NNC(C2)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C14 compound treatment 279.5 93.2 0.49 300.1 108.0 0.56 0.7417 0.9973 1591482 ChemDiv1_009210 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccc(Cl)cc2)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C15 compound treatment 278.6 92.3 0.48 293.6 102.0 0.53 0.7145 0.9989 1974459 ChemDiv1_009211 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccc(C)cc3nc2N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C16 compound treatment 275.6 89.3 0.47 287.6 95.8 0.5 0.6814 0.9995 1974460 ChemDiv1_009212 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C17 compound treatment 276.5 90.2 0.47 285.8 94.0 0.49 0.6781 0.9998 1270904 ChemDiv1_009213 CCOC(=O)COc1nc(C)c(Br)c(COC)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C18 compound treatment 277.1 90.8 0.47 286.2 94.4 0.49 0.6818 0.9998 1974461 ChemDiv1_009214 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C19 compound treatment 278.7 92.4 0.48 288.3 96.5 0.5 0.6954 0.9998 1974462 ChemDiv1_009215 CN(C)Cc1c(O)ccc2c([N+](=O)[O-])c(C)n(c3ccc(C)cc3)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C20 compound treatment 274.2 87.9 0.46 287.9 96.1 0.5 0.6773 0.9991 1338156 ChemDiv1_009216 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C21 compound treatment 276.4 90.1 0.47 287.7 95.9 0.5 0.6847 0.9996 1974463 ChemDiv1_009217 Cc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C22 compound treatment 274.5 88.2 0.46 281.1 89.3 0.46 0.6534 1.0 1974464 ChemDiv1_009218 CC(=O)c1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C(F)(F)F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C23 mock treatment 281.1 94.8 0.49 290.6 98.8 0.51 0.7127 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 C24 mock treatment 80.4 -106.0 -0.55 80.3 -112.0 -0.58 -0.8006 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D01 compound treatment 280.7 94.4 0.49 292.1 100.0 0.52 0.7167 0.9996 1974465 ChemDiv1_009219 COc1ccc(cc1)C/2=NN(C(=O)\C2=C/c3ccc(OC)c(OC)c3OC)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D02 compound treatment 280.1 93.8 0.49 292.0 100.0 0.52 0.7141 0.9995 1261581 ChemDiv1_009220 Cc1cc(nc(NCc2ccccc2)n1)N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D03 compound treatment 279.1 92.8 0.48 289.5 97.7 0.51 0.7013 0.9997 1974466 ChemDiv1_009221 COc1ccc(cc1CSc2nc3ccccc3o2)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D04 compound treatment 285.0 98.7 0.51 296.7 105.0 0.55 0.7495 0.9996 1785883 ChemDiv1_009222 COc1cc(cc(OC)c1O)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D05 compound treatment 278.1 91.8 0.48 295.1 103.0 0.54 0.7182 0.9984 1974467 ChemDiv1_009223 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)C(F)(F)F)C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D06 compound treatment 282.3 96.0 0.5 296.9 105.0 0.55 0.7403 0.9991 1974468 ChemDiv1_009224 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4Br)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D07 compound treatment 277.2 90.9 0.47 295.4 104.0 0.54 0.7159 0.998 1974469 ChemDiv1_009225 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5ccccn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D08 compound treatment 280.1 93.8 0.49 298.4 107.0 0.55 0.7377 0.9981 1537998 ChemDiv1_009226 COc1cc(cc(OC)c1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D09 compound treatment 279.5 93.2 0.49 293.2 101.0 0.53 0.7163 0.9992 1974470 ChemDiv1_009227 COc1ccc2nc(N3CCCCC3)c(/C=C/4\N(C(=O)C)C(=S)NC4=O)cc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D10 compound treatment 273.3 87.0 0.45 296.2 104.0 0.54 0.7045 0.9961 1605988 ChemDiv1_009228 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D11 compound treatment 277.3 91.0 0.47 291.4 99.6 0.52 0.7016 0.9991 1619636 ChemDiv1_009229 COc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4sc5ccccc5c4Cl)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D12 compound treatment 272.8 86.5 0.45 297.0 105.0 0.55 0.7056 0.9955 1392786 ChemDiv1_009230 COc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D13 compound treatment 267.3 81.0 0.42 282.7 90.9 0.47 0.6327 0.9985 1871238 ChemDiv1_009231 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D14 compound treatment 276.4 90.1 0.47 296.6 105.0 0.54 0.7174 0.9973 1625229 ChemDiv1_009232 CCOc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D15 compound treatment 277.2 90.9 0.47 290.5 98.7 0.51 0.6979 0.9992 1974471 ChemDiv1_009233 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D16 compound treatment 276.8 90.5 0.47 298.5 107.0 0.55 0.7259 0.9968 1782128 ChemDiv1_009234 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(c3)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D17 compound treatment 277.3 91.0 0.47 294.4 103.0 0.53 0.7126 0.9983 1871392 ChemDiv1_009235 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc(cc4)[N+](=O)[O-])C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D18 compound treatment 273.2 86.9 0.45 291.4 99.6 0.52 0.6865 0.9978 1600942 ChemDiv1_009236 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)Nc3ccc(Br)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D19 compound treatment 276.1 89.8 0.47 287.6 95.8 0.5 0.6832 0.9995 1974472 ChemDiv1_009237 [O-][N+](=O)c1ccc(cc1Sc2nc3ccccc3[nH]2)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D20 compound treatment 276.8 90.5 0.47 285.9 94.1 0.49 0.6795 0.9998 1299683 ChemDiv1_009238 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D21 compound treatment 276.7 90.4 0.47 281.6 89.8 0.47 0.6634 1.0 1974473 ChemDiv1_009239 OCCCn1c(/C=C/2\C(=O)N(Cc3ccccc3)c4ccccc24)nc5ccccc5c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D22 compound treatment 275.3 89.0 0.46 283.2 91.4 0.47 0.6641 0.9999 1974474 ChemDiv1_009240 CN1C(=O)C(=c2sc3=NC(=C(C(c4ccc(OC(=O)c5ccco5)cc4)n3c2=O)C(=O)OCC=C)C)c6ccccc16 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D23 mock treatment 278.5 92.2 0.48 286.1 94.3 0.49 0.6866 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 D24 mock treatment 78.3 -108.0 -0.56 83.4 -108.0 -0.56 -0.797 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E01 compound treatment 283.4 97.1 0.51 295.0 103.0 0.54 0.7373 0.9996 1382464 ChemDiv1_009241 CC1CC(C)CN(C1)c2nc(nc3ccccc23)c4ccccc4O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E02 compound treatment 283.4 97.1 0.51 294.6 103.0 0.53 0.7359 0.9996 1974475 ChemDiv1_009242 COc1ccccc1/C=C(/NC(=O)c2cccc(C)c2)\C(=O)NCCc3c[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E03 compound treatment 276.8 90.5 0.47 295.6 104.0 0.54 0.7152 0.9978 1974476 ChemDiv1_009243 CN1CCN(CC1)c2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E04 compound treatment 280.4 94.1 0.49 297.6 106.0 0.55 0.7358 0.9984 1974477 ChemDiv1_009244 Cc1ccc(cc1C)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCN(CC3)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E05 compound treatment 281.4 95.1 0.5 291.7 99.9 0.52 0.7178 0.9997 1619032 ChemDiv1_009245 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E06 compound treatment 275.3 89.0 0.46 296.2 104.0 0.54 0.7119 0.997 1664143 ChemDiv1_009246 CCOc1ccccc1C2C(C(=O)OC)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E07 compound treatment 282.4 96.1 0.5 297.4 106.0 0.55 0.7425 0.999 1738113 ChemDiv1_009247 CCOC(=O)c1c(CN2CCOCC2)n(C)c3ccc(OC)c(c13)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E08 compound treatment 281.1 94.8 0.49 299.4 108.0 0.56 0.745 0.9981 1974478 ChemDiv1_009248 Clc1cc(Cl)cc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E09 compound treatment 279.6 93.3 0.49 297.4 106.0 0.55 0.7321 0.9982 1574393 ChemDiv1_009249 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccco2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E10 compound treatment 280.4 94.1 0.49 300.3 108.0 0.56 0.7458 0.9976 1310386 ChemDiv1_009250 O=C(CSc1nc2CCCCc2c(c1C#N)c3cccnc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E11 compound treatment 276.1 89.8 0.47 295.6 104.0 0.54 0.7126 0.9975 1718366 ChemDiv1_009251 COc1ccc(cc1OC)C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E12 compound treatment 282.1 95.8 0.5 295.1 103.0 0.54 0.7329 0.9994 1330645 ChemDiv1_009252 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3ccc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E13 compound treatment 273.7 87.4 0.46 291.0 99.2 0.52 0.6869 0.9981 1199301 ChemDiv1_009253 Clc1ccc(cc1)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E14 compound treatment 273.6 87.3 0.46 293.1 101.0 0.53 0.6942 0.9974 1599017 ChemDiv1_009254 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(C)cc2)C#N)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E15 compound treatment 278.5 92.2 0.48 297.0 105.0 0.55 0.7266 0.998 1590010 ChemDiv1_009255 Fc1ccc(Cc2cnc(NC(=O)C3CCCO3)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E16 compound treatment 280.4 94.1 0.49 291.8 100.0 0.52 0.7145 0.9996 1733256 ChemDiv1_009256 CC1=C(C(C(=C(N1)SCC(=O)Nc2cc(C)ccc2C)C#N)c3ccco3)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E17 compound treatment 348.4 162.0 0.85 354.0 162.0 0.84 1.194 1.0 1173606 ChemDiv1_009257 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCN(C)CC4)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E18 compound treatment 277.4 91.1 0.48 291.6 99.8 0.52 0.7027 0.9991 1452253 ChemDiv1_009258 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cc(C)ccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E19 compound treatment 278.1 91.8 0.48 288.5 96.7 0.5 0.6939 0.9997 1974479 ChemDiv1_009259 CCN(CC)c1nc(nc(C)c1[N+](=O)[O-])N2CCOCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E20 compound treatment 274.6 88.3 0.46 290.4 98.6 0.51 0.688 0.9986 1300103 ChemDiv1_009260 COc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E21 compound treatment 276.8 90.5 0.47 285.7 93.9 0.49 0.6788 0.9999 1974480 ChemDiv1_009261 Cc1nc(nc(Nc2ccc(Cl)cc2)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E22 compound treatment 276.9 90.6 0.47 289.1 97.3 0.51 0.6917 0.9994 1519835 ChemDiv1_009262 CCOc1ccccc1C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccccc4CC)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E23 mock treatment 278.3 92.0 0.48 289.2 97.4 0.51 0.6972 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 E24 mock treatment 77.7 -109.0 -0.57 81.4 -110.0 -0.57 -0.8065 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F01 compound treatment 312.1 126.0 0.66 325.2 133.0 0.69 0.9542 0.9996 1974481 ChemDiv1_009263 COc1cc(cc(Br)c1OCc2ccc(F)cc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F02 compound treatment 281.3 95.0 0.5 293.9 102.0 0.53 0.7256 0.9994 1607740 ChemDiv1_009264 Cc1cc(nc(NCc2ccccc2)n1)N3CCN(CC3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F03 compound treatment 277.2 90.9 0.47 296.7 105.0 0.55 0.7207 0.9976 1121526 ChemDiv1_009265 COc1ccc(cc1CN2CCN(CC2)c3ccc(F)cc3)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F04 compound treatment 279.5 93.2 0.49 293.9 102.0 0.53 0.7189 0.9991 1974482 ChemDiv1_009266 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4cccc(OC(=O)N5CCOCC5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F05 compound treatment 291.8 106.0 0.55 307.4 116.0 0.6 0.8139 0.999 1974483 ChemDiv1_009267 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(Br)c4)C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F06 compound treatment 278.1 91.8 0.48 296.2 104.0 0.54 0.7222 0.9981 1974484 ChemDiv1_009268 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4cccc(OC(=O)c5ccco5)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F07 compound treatment 283.0 96.7 0.5 293.5 102.0 0.53 0.7304 0.9997 1974485 ChemDiv1_009269 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F08 compound treatment 280.9 94.6 0.49 299.1 107.0 0.56 0.7432 0.9981 1192407 ChemDiv1_009270 COc1ccc(cc1COc2ccc(F)cc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F09 compound treatment 279.0 92.7 0.48 295.3 103.0 0.54 0.7222 0.9986 1974486 ChemDiv1_009271 COc1ccc2nc(N3CCOCC3)c(/C=C/4\N(C(=O)C)C(=S)NC4=O)cc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F10 compound treatment 276.7 90.4 0.47 295.8 104.0 0.54 0.7156 0.9977 1617032 ChemDiv1_009272 COc1ccc(cc1Cn2nc(C)c(Br)c2C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F11 compound treatment 276.6 90.3 0.47 300.8 109.0 0.57 0.7336 0.9958 1413357 ChemDiv1_009273 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F12 compound treatment 276.4 90.1 0.47 295.8 104.0 0.54 0.7145 0.9976 1623461 ChemDiv1_009274 COc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F13 compound treatment 277.4 91.1 0.48 296.3 104.0 0.54 0.72 0.9978 1293782 ChemDiv1_009275 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccc(C)cc5c4=O)C(=O)OCC6CCCO6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F14 compound treatment 277.7 91.4 0.48 296.4 105.0 0.54 0.7215 0.9979 1735121 ChemDiv1_009276 CCOc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F15 compound treatment 275.3 89.0 0.46 293.3 101.0 0.53 0.7012 0.998 1974487 ChemDiv1_009277 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F16 compound treatment 280.1 93.8 0.49 299.6 108.0 0.56 0.7421 0.9977 1974488 ChemDiv1_009278 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(Br)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F17 compound treatment 274.9 88.6 0.46 290.5 98.7 0.51 0.6894 0.9987 1133378 ChemDiv1_009279 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccccc5c4=O)C(=O)OC6CCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F18 compound treatment 279.4 93.1 0.49 294.5 103.0 0.53 0.7207 0.9989 1584331 ChemDiv1_009280 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)Nc3ccccc3C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F19 compound treatment 277.1 90.8 0.47 292.0 100.0 0.52 0.7031 0.9989 1974489 ChemDiv1_009281 Nc1ncnc2[nH]c(Sc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F20 compound treatment 275.3 89.0 0.46 291.3 99.5 0.52 0.6939 0.9986 1691779 ChemDiv1_009282 COc1cc(cc(OC)c1OC)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F21 compound treatment 274.7 88.4 0.46 291.6 99.8 0.52 0.6928 0.9983 1974490 ChemDiv1_009283 CC(=O)NC1=NN(C(=O)C)C2(S1)C(=O)N(C(=O)C)c3ccccc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F22 compound treatment 274.1 87.8 0.46 288.1 96.3 0.5 0.6777 0.999 1263978 ChemDiv1_009284 Cc1cccn2cc(nc12)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F23 mock treatment 277.7 91.4 0.48 285.5 93.7 0.49 0.6814 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 F24 mock treatment 74.1 -112.0 -0.59 81.6 -110.0 -0.57 -0.8191 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G01 compound treatment 282.6 96.3 0.5 295.6 104.0 0.54 0.7366 0.9994 1318548 ChemDiv1_009285 COc1ccc(Nc2nc(nc3ccccc23)c4ccccc4O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G02 compound treatment 281.2 94.9 0.5 291.3 99.5 0.52 0.7156 0.9998 1974491 ChemDiv1_009286 COc1ccc(/C=C(/NC(=O)c2ccco2)\C(=O)NCCc3c[nH]c4ccccc34)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G03 compound treatment 279.4 93.1 0.49 296.6 105.0 0.54 0.7285 0.9984 1533661 ChemDiv1_009287 CCCOc1ccc(cc1)c2nc(N3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G04 compound treatment 279.5 93.2 0.49 299.7 108.0 0.56 0.7402 0.9975 1974492 ChemDiv1_009288 Cc1ccc(cc1C)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCN(CC3)c4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G05 compound treatment 278.9 92.6 0.48 294.1 102.0 0.53 0.7174 0.9989 1685620 ChemDiv1_009289 CC(C)Sc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCOC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G06 compound treatment 275.5 89.2 0.47 296.5 105.0 0.54 0.7137 0.997 1211297 ChemDiv1_009290 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G07 compound treatment 282.4 96.1 0.5 296.4 105.0 0.54 0.7388 0.9992 1366316 ChemDiv1_009291 CCOC(=O)c1c(C)n(C)c2cc(CN(C)C)c(O)c(c12)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G08 compound treatment 281.2 94.9 0.5 302.4 111.0 0.57 0.7564 0.9972 1974493 ChemDiv1_009292 Clc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G09 compound treatment 274.7 88.4 0.46 297.1 105.0 0.55 0.713 0.9964 1669345 ChemDiv1_009293 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2cccs2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G10 compound treatment 278.6 92.3 0.48 298.3 106.0 0.55 0.7318 0.9976 1470743 ChemDiv1_009294 CC1C(=C(NC2=C1C(=O)CC(C)(C)C2)SCC(=O)Nc3ccc(Br)cc3)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G11 compound treatment 279.0 92.7 0.48 298.3 106.0 0.55 0.7332 0.9977 1636353 ChemDiv1_009295 COc1ccccc1c2coc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G12 compound treatment 280.9 94.6 0.49 297.9 106.0 0.55 0.7388 0.9985 1299014 ChemDiv1_009296 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G13 compound treatment 273.5 87.2 0.45 296.5 105.0 0.54 0.7063 0.996 1146853 ChemDiv1_009297 COc1ccc(cc1OC)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G14 compound treatment 275.9 89.6 0.47 295.8 104.0 0.54 0.7126 0.9974 1383277 ChemDiv1_009298 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C(C(=O)OC)C(=O)N2)c3cc(OC)c(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G15 compound treatment 280.1 93.8 0.49 302.3 110.0 0.57 0.752 0.9968 1882627 ChemDiv1_009299 O=C1Nc2ccccc2C31Oc4ccccc4C5CC(=NN53)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G16 compound treatment 277.8 91.5 0.48 294.5 103.0 0.53 0.7148 0.9985 1612715 ChemDiv1_009300 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)C(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G17 compound treatment 379.4 193.0 1.01 389.5 198.0 1.03 1.4388 1.0 1662053 ChemDiv1_009301 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCN(C)CC4)c(=O)n2C1c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G18 compound treatment 279.1 92.8 0.48 287.3 95.5 0.5 0.6932 0.9999 1404111 ChemDiv1_009302 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(F)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G19 compound treatment 277.6 91.3 0.48 288.8 97.0 0.5 0.6932 0.9996 1974494 ChemDiv1_009303 Cc1nc(nc(NCc2ccccc2)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G20 compound treatment 278.7 92.4 0.48 291.8 100.0 0.52 0.7082 0.9993 1148213 ChemDiv1_009304 Clc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G21 compound treatment 275.9 89.6 0.47 286.5 94.7 0.49 0.6784 0.9997 1974495 ChemDiv1_009305 Cc1nc(nc(Nc2cccc(Cl)c2)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G22 compound treatment 274.7 88.4 0.46 288.6 96.8 0.5 0.6817 0.9991 1583699 ChemDiv1_009306 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G23 mock treatment 279.6 93.3 0.49 287.3 95.5 0.5 0.695 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 G24 mock treatment 79.9 -106.0 -0.56 83.7 -108.0 -0.56 -0.79 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H01 compound treatment 281.4 95.1 0.5 293.1 101.0 0.53 0.723 0.9996 1974496 ChemDiv1_009307 COc1cc(ccc1OCc2ccccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H02 compound treatment 280.3 94.0 0.49 295.4 104.0 0.54 0.7274 0.9989 1610447 ChemDiv1_009308 Cc1ccc(Nc2cc(C)nc(NCc3ccccc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H03 compound treatment 279.3 93.0 0.49 297.9 106.0 0.55 0.7329 0.998 1328250 ChemDiv1_009309 COc1ccc(cc1CN2CCCc3ccccc23)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H04 compound treatment 278.7 92.4 0.48 295.7 104.0 0.54 0.7226 0.9984 1785880 ChemDiv1_009310 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4ccc(OC(=O)N5CCOCC5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H05 compound treatment 281.0 94.7 0.49 296.3 104.0 0.54 0.7333 0.9989 1974497 ChemDiv1_009311 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H06 compound treatment 276.6 90.3 0.47 295.4 104.0 0.54 0.7137 0.9978 1974498 ChemDiv1_009312 CCCOc1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H07 compound treatment 277.6 91.3 0.48 295.8 104.0 0.54 0.7189 0.998 1299411 ChemDiv1_009313 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4cccc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H08 compound treatment 278.4 92.1 0.48 299.0 107.0 0.56 0.7336 0.9973 1399300 ChemDiv1_009314 COc1ccc(cc1COc2ccccc2F)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H09 compound treatment 280.6 94.3 0.49 296.1 104.0 0.54 0.7311 0.9988 1369453 ChemDiv1_009315 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4cc(OC)ccc4oc3=O)cc2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H10 compound treatment 277.9 91.6 0.48 301.2 109.0 0.57 0.7398 0.9963 1460439 ChemDiv1_009316 COc1ccc(cc1COc2ccc(NC(=O)C)cc2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H11 compound treatment 275.0 88.7 0.46 296.7 105.0 0.55 0.7126 0.9967 1974499 ChemDiv1_009317 CCOCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H12 compound treatment 277.6 91.3 0.48 294.1 102.0 0.53 0.7126 0.9985 1128797 ChemDiv1_009318 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H13 compound treatment 276.0 89.7 0.47 291.1 99.3 0.52 0.6957 0.9988 1974500 ChemDiv1_009319 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OCC)c3)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H14 compound treatment 275.6 89.3 0.47 296.4 105.0 0.54 0.7137 0.9971 1974501 ChemDiv1_009320 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3ccc(Br)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H15 compound treatment 276.8 90.5 0.47 297.0 105.0 0.55 0.7203 0.9973 1974502 ChemDiv1_009321 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c3ccc(F)c(Br)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H16 compound treatment 280.3 94.0 0.49 297.5 106.0 0.55 0.7351 0.9984 1179973 ChemDiv1_009322 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Br)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H17 compound treatment 276.4 90.1 0.47 293.2 101.0 0.53 0.7049 0.9984 1206290 ChemDiv1_009323 CC(C)COC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H18 compound treatment 276.2 89.9 0.47 293.7 102.0 0.53 0.706 0.9982 1736513 ChemDiv1_009324 CC1=C(C(NC(=O)N1)c2ccc(O)cc2)C(=O)Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H19 compound treatment 276.2 89.9 0.47 290.1 98.3 0.51 0.6928 0.9991 1349898 ChemDiv1_009325 CCn1c(SCC(=O)O)nc2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H20 compound treatment 277.3 91.0 0.47 290.3 98.5 0.51 0.6976 0.9993 1974503 ChemDiv1_009326 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H21 compound treatment 275.4 89.1 0.46 286.9 95.1 0.49 0.6781 0.9995 1974504 ChemDiv1_009327 CCCCCOC(=O)CSc1nnc(o1)c2cc(OC)c(OC)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H22 compound treatment 278.5 92.2 0.48 281.7 89.9 0.47 0.6704 0.9999 1552357 ChemDiv1_009328 Cc1ccn2cc(nc2c1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H23 mock treatment 280.6 94.3 0.49 291.1 99.3 0.52 0.7127 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 H24 mock treatment 77.0 -109.0 -0.57 85.9 -106.0 -0.55 -0.7926 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I01 compound treatment 283.3 97.0 0.51 293.6 102.0 0.53 0.7318 0.9998 1457150 ChemDiv1_009329 COc1ccccc1Nc2nc(nc3ccccc23)c4ccccc4O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I02 compound treatment 283.7 97.4 0.51 294.2 102.0 0.53 0.7355 0.9997 1974505 ChemDiv1_009330 Cc1ccc(cc1)C(=O)N/C(=C\c2cccnc2)/C(=O)NCCc3c[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I03 compound treatment 282.0 95.7 0.5 297.4 106.0 0.55 0.741 0.9989 1974506 ChemDiv1_009331 Brc1ccc(Nc2nc(nc3ccccc23)c4cccnc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I04 compound treatment 280.3 94.0 0.49 295.3 103.0 0.54 0.727 0.9989 1974507 ChemDiv1_009332 Cc1ccc(cc1C)C(=O)N/C(=C\c2cccs2)/C(=O)N3CCN(CC3)c4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I05 compound treatment 278.0 91.7 0.48 299.1 107.0 0.56 0.7325 0.9971 1244909 ChemDiv1_009333 CC(=C)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCOC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I06 compound treatment 277.7 91.4 0.48 296.1 104.0 0.54 0.7204 0.998 1628687 ChemDiv1_009334 CCOC(=O)C1=C(C)NC(=C(C#N)C1CC(C)C)SCC(=O)c2ccc(Cl)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I07 compound treatment 276.3 90.0 0.47 297.5 106.0 0.55 0.7203 0.997 1646675 ChemDiv1_009335 CCOC(=O)c1c(CNc2ccccc2)n(c3ccccc3)c4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I08 compound treatment 279.1 92.8 0.48 296.4 105.0 0.54 0.7266 0.9983 1974508 ChemDiv1_009336 O=C(CSC1=C(C#N)C(CC(=O)N1)c2cccs2)Nc3ccc4ccccc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I09 compound treatment 268.6 82.3 0.43 298.5 107.0 0.55 0.6956 0.992 1974509 ChemDiv1_009337 Brc1ccc(cc1)c2noc(Cn3cc(C=O)c4ccccc34)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I10 compound treatment 280.3 94.0 0.49 296.4 105.0 0.54 0.7311 0.9987 1646134 ChemDiv1_009338 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cc(OC)c(Cl)cc2OC)C#N)c3ccccc3OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I11 compound treatment 278.9 92.6 0.48 299.3 107.0 0.56 0.7365 0.9974 1974510 ChemDiv1_009339 CN(C)CCCNc1nc(nc2ccccc12)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I12 compound treatment 277.3 91.0 0.47 294.4 103.0 0.53 0.7126 0.9983 1717483 ChemDiv1_009340 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(OC)cc2)C#N)c3ccc(cc3)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I13 compound treatment 282.5 96.2 0.5 301.1 109.0 0.57 0.7564 0.9981 1974511 ChemDiv1_009341 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccccc3nc2N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I14 compound treatment 279.6 93.3 0.49 297.9 106.0 0.55 0.734 0.9981 1974512 ChemDiv1_009342 COc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)C(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I15 compound treatment 283.5 97.2 0.51 299.5 108.0 0.56 0.7542 0.9988 1974513 ChemDiv1_009343 O=C1N(Cc2ccccc2)c3ccccc3C41Oc5ccccc5C6CC(=NN64)c7ccco7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I16 compound treatment 280.5 94.2 0.49 295.9 104.0 0.54 0.73 0.9989 1974514 ChemDiv1_009344 COC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(c1C#N)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I17 compound treatment 274.8 88.5 0.46 295.2 103.0 0.54 0.7064 0.9971 1974515 ChemDiv1_009345 O=C(CN1C(=O)c2ccccc2C1=O)OCCOCCNC3=NS(=O)(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I18 compound treatment 275.4 89.1 0.46 292.2 100.0 0.52 0.6975 0.9983 1472479 ChemDiv1_009346 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(OC)c2)C#N)c3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I19 compound treatment 280.2 93.9 0.49 293.9 102.0 0.53 0.7215 0.9992 1974516 ChemDiv1_009347 Cc1nc(nc(NC2CCCCC2)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I20 compound treatment 276.8 90.5 0.47 288.3 96.5 0.5 0.6884 0.9995 1463596 ChemDiv1_009348 COc1cc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)o4)c(OC)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I21 compound treatment 273.5 87.2 0.45 286.5 94.7 0.49 0.6696 0.9992 1974517 ChemDiv1_009349 Cc1nc(nc(Nc2cccc(F)c2)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I22 compound treatment 277.9 91.6 0.48 287.3 95.5 0.5 0.6888 0.9998 1220634 ChemDiv1_009350 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I23 mock treatment 278.4 92.1 0.48 284.9 93.1 0.48 0.6818 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 I24 mock treatment 83.2 -103.0 -0.54 83.5 -108.0 -0.56 -0.7785 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J01 compound treatment 284.6 98.3 0.51 290.5 98.7 0.51 0.7252 1.0 1974518 ChemDiv1_009351 COC(=O)c1ccc(COc2ccc(cc2OC)C3C(=C(N)Oc4[nH]nc(C)c34)C#N)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J02 compound treatment 292.5 106.0 0.55 298.8 107.0 0.56 0.7849 1.0 1135585 ChemDiv1_009352 CCOC(=O)c1ccc(Nc2cc(C)nc(NCc3ccccc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J03 compound treatment 281.2 94.9 0.5 294.7 103.0 0.53 0.7281 0.9993 1575659 ChemDiv1_009353 COc1ccc(cc1Cn2nnc3ccccc23)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J04 compound treatment 282.8 96.5 0.5 296.4 105.0 0.54 0.7403 0.9993 1974519 ChemDiv1_009354 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J05 compound treatment 279.8 93.5 0.49 298.1 106.0 0.55 0.7355 0.9981 1974520 ChemDiv1_009355 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4)C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J06 compound treatment 279.4 93.1 0.49 295.9 104.0 0.54 0.7259 0.9986 1974521 ChemDiv1_009356 COc1ccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J07 compound treatment 276.4 90.1 0.47 294.3 102.0 0.53 0.7089 0.9981 1974522 ChemDiv1_009357 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5cccc(C)n5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J08 compound treatment 281.8 95.5 0.5 302.3 110.0 0.57 0.7583 0.9975 1974523 ChemDiv1_009358 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J09 compound treatment 277.0 90.7 0.47 295.1 103.0 0.54 0.7141 0.998 1690454 ChemDiv1_009359 COc1ccccc1N2CCN(CC2)C(=O)c3cc4cccc(CC=C)c4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J10 compound treatment 281.1 94.8 0.49 300.0 108.0 0.56 0.7472 0.998 1401248 ChemDiv1_009360 COc1cccc(OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3Cc5ccco5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J11 compound treatment 275.0 88.7 0.46 293.8 102.0 0.53 0.7019 0.9977 1871365 ChemDiv1_009361 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J12 compound treatment 277.6 91.3 0.48 294.1 102.0 0.53 0.7126 0.9985 1431253 ChemDiv1_009362 CC(C)c1ccc(cc1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J13 compound treatment 275.7 89.4 0.47 295.4 104.0 0.54 0.7104 0.9974 1974524 ChemDiv1_009363 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCSCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J14 compound treatment 277.0 90.7 0.47 291.5 99.7 0.52 0.7009 0.999 1974525 ChemDiv1_009364 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J15 compound treatment 279.9 93.6 0.49 292.2 100.0 0.52 0.7141 0.9995 1709195 ChemDiv1_009365 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J16 compound treatment 277.0 90.7 0.47 291.2 99.4 0.52 0.6998 0.999 1974526 ChemDiv1_009366 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccccc3Cl)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J17 compound treatment 275.1 88.8 0.46 294.2 102.0 0.53 0.7038 0.9976 1974527 ChemDiv1_009367 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J18 compound treatment 277.6 91.3 0.48 289.8 98.0 0.51 0.6968 0.9994 1974528 ChemDiv1_009368 CC1=C(C(NC(=O)N1)c2ccc(Br)cc2)C(=O)Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J19 compound treatment 364.7 178.0 0.93 367.1 175.0 0.91 1.3022 0.9999 1974529 ChemDiv1_009369 O=C1/C(=C/c2ccc(o2)c3ccc(cc3)S(=O)(=O)Nc4nccs4)/Sc5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J20 compound treatment 274.7 88.4 0.46 289.8 98.0 0.51 0.6861 0.9988 1641590 ChemDiv1_009370 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J21 compound treatment 277.5 91.2 0.48 287.4 95.6 0.5 0.6876 0.9998 1325797 ChemDiv1_009371 Cc1ccc(cc1)n2ncc3c(Nc4ccc(Br)cc4)ncnc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J22 compound treatment 277.3 91.0 0.47 286.2 94.4 0.49 0.6825 0.9999 1544497 ChemDiv1_009372 Cc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J23 mock treatment 279.5 93.2 0.49 285.1 93.3 0.48 0.6866 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 J24 mock treatment 79.4 -107.0 -0.56 81.1 -111.0 -0.58 -0.8014 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K01 compound treatment 281.3 95.0 0.5 294.1 102.0 0.53 0.7263 0.9994 1227490 ChemDiv1_009373 COc1ccc(Nc2nc(nc3ccccc23)c4ccccc4O)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K02 compound treatment 281.2 94.9 0.5 294.6 103.0 0.53 0.7278 0.9993 1974530 ChemDiv1_009374 O=C(NCCc1c[nH]c2ccccc12)/C(=C/c3ccco3)/NC(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K03 compound treatment 280.2 93.9 0.49 295.0 103.0 0.54 0.7255 0.999 1974531 ChemDiv1_009375 Fc1ccc(Nc2nc(nc3ccccc23)c4cccnc4)cc1F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K04 compound treatment 279.5 93.2 0.49 293.8 102.0 0.53 0.7185 0.9991 1974532 ChemDiv1_009376 Cc1ccc(cc1C)C(=O)N/C(=C/c2cccs2)/C(=O)NCCc3c[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K05 compound treatment 278.2 91.9 0.48 296.8 105.0 0.55 0.7248 0.9979 1737091 ChemDiv1_009377 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K06 compound treatment 281.5 95.2 0.5 295.2 103.0 0.54 0.7311 0.9992 1974533 ChemDiv1_009378 Cc1ccsc1C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K07 compound treatment 277.2 90.9 0.47 296.2 104.0 0.54 0.7189 0.9978 1440960 ChemDiv1_009379 CCOC(=O)c1c(CNc2cccc(Cl)c2)n(c3ccccc3)c4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K08 compound treatment 276.1 89.8 0.47 296.8 105.0 0.55 0.717 0.9971 1974534 ChemDiv1_009380 Brc1cccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K09 compound treatment 284.8 98.5 0.51 295.2 103.0 0.54 0.7432 0.9998 1701491 ChemDiv1_009381 Clc1cc(NC(=O)c2ccc3OCCOc3c2)ccc1N4CCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K10 compound treatment 277.2 90.9 0.47 295.4 104.0 0.54 0.7159 0.998 1974535 ChemDiv1_009382 COCCOC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3cccc(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K11 compound treatment 277.4 91.1 0.48 291.9 100.0 0.52 0.7038 0.999 1974536 ChemDiv1_009383 CCN(CC)CCCNc1nc(nc2ccccc12)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K12 compound treatment 278.1 91.8 0.48 293.3 101.0 0.53 0.7115 0.9988 1367681 ChemDiv1_009384 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccc(cc3)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K13 compound treatment 277.1 90.8 0.47 295.4 104.0 0.54 0.7156 0.998 1974537 ChemDiv1_009385 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccccc3nc2N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K14 compound treatment 275.2 88.9 0.46 290.4 98.6 0.51 0.6902 0.9988 1303771 ChemDiv1_009386 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(OC)cc2)C#N)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K15 compound treatment 281.0 94.7 0.49 292.3 100.0 0.52 0.7186 0.9996 1974538 ChemDiv1_009387 [O-][N+](=O)c1ccc(cc1n2nc(c3ccc(F)cc3)c4ccccc4c2=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K16 compound treatment 278.1 91.8 0.48 297.2 105.0 0.55 0.7259 0.9978 1974539 ChemDiv1_009388 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K17 compound treatment 274.6 88.3 0.46 287.3 95.5 0.5 0.6766 0.9993 1974540 ChemDiv1_009389 Clc1ccc(OCC(=O)OCCCNC2=NS(=O)(=O)c3ccccc23)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K18 compound treatment 274.7 88.4 0.46 291.7 99.9 0.52 0.6931 0.9983 1974541 ChemDiv1_009390 CC(=O)c1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K19 compound treatment 274.3 88.0 0.46 291.4 99.6 0.52 0.6905 0.9982 1974542 ChemDiv1_009391 Cc1nc(nc(N2CCCCC2)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K20 compound treatment 277.5 91.2 0.48 292.7 101.0 0.52 0.7071 0.9988 1653193 ChemDiv1_009392 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K21 compound treatment 277.9 91.6 0.48 283.9 92.1 0.48 0.6763 1.0 1974543 ChemDiv1_009393 Cc1nc(nc(Nc2ccc(F)cc2F)c1[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K22 compound treatment 273.7 87.4 0.46 282.5 90.7 0.47 0.6556 0.9999 1458187 ChemDiv1_009394 Cc1ccc(o1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4c(C)cc(C)cc4C)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K23 mock treatment 281.3 95.0 0.5 284.7 92.9 0.48 0.6917 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 K24 mock treatment 79.3 -107.0 -0.56 81.9 -110.0 -0.57 -0.7988 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L01 compound treatment 284.4 98.1 0.51 295.3 103.0 0.54 0.7421 0.9997 1607435 ChemDiv1_009395 CCOc1cc(ccc1OCc2cccc(F)c2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L02 compound treatment 294.6 108.0 0.56 305.0 113.0 0.59 0.8154 0.9998 1508513 ChemDiv1_009396 COC(=O)c1ccc(Oc2cc(C)nc(NCc3ccccc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L03 compound treatment 282.4 96.1 0.5 294.3 102.0 0.53 0.7311 0.9995 1606464 ChemDiv1_009397 COc1ccc(cc1COc2ccccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L04 compound treatment 282.5 96.2 0.5 292.7 101.0 0.52 0.7256 0.9998 1974544 ChemDiv1_009398 NC1=C(C#N)C2(C(=O)Nc3ccc(F)cc32)c4c(n[nH]c4O1)c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L05 compound treatment 279.0 92.7 0.48 293.6 102.0 0.53 0.716 0.999 1974545 ChemDiv1_009399 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cc(ccc4C)[N+](=O)[O-])C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L06 compound treatment 279.5 93.2 0.49 293.9 102.0 0.53 0.7189 0.9991 1974546 ChemDiv1_009400 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccccc5C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L07 compound treatment 275.5 89.2 0.47 294.9 103.0 0.54 0.7078 0.9975 1974547 ChemDiv1_009401 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(C)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L08 compound treatment 282.3 96.0 0.5 294.4 103.0 0.53 0.7311 0.9995 1591556 ChemDiv1_009402 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L09 compound treatment 280.7 94.4 0.49 298.9 107.0 0.56 0.7417 0.9981 1175761 ChemDiv1_009403 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)sc(C)c1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L10 compound treatment 282.3 96.0 0.5 300.6 109.0 0.57 0.7539 0.9982 1974548 ChemDiv1_009404 OC(=O)c1cc(O)ccc1NC(=O)c2cccc(c2)N3C(=O)c4cccc5c(ccc(C3=O)c45)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L11 compound treatment 274.3 88.0 0.46 293.7 102.0 0.53 0.699 0.9975 1974549 ChemDiv1_009405 COCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L12 compound treatment 278.1 91.8 0.48 293.8 102.0 0.53 0.7134 0.9987 1567959 ChemDiv1_009406 CC(C)c1ccc(cc1)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L13 compound treatment 272.5 86.2 0.45 288.6 96.8 0.5 0.6736 0.9984 1974550 ChemDiv1_009407 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L14 compound treatment 279.0 92.7 0.48 293.8 102.0 0.53 0.7167 0.999 1242920 ChemDiv1_009408 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L15 compound treatment 277.2 90.9 0.47 293.4 102.0 0.53 0.7086 0.9986 1580637 ChemDiv1_009409 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L16 compound treatment 283.3 97.0 0.51 291.7 99.9 0.52 0.7248 0.9999 1434701 ChemDiv1_009410 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(OC)c(OC)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L17 compound treatment 276.6 90.3 0.47 290.9 99.1 0.51 0.6972 0.999 1974551 ChemDiv1_009411 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L18 compound treatment 276.3 90.0 0.47 286.5 94.7 0.49 0.6799 0.9997 1190558 ChemDiv1_009412 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L19 compound treatment 273.6 87.3 0.46 286.9 95.1 0.49 0.6714 0.9992 1974552 ChemDiv1_009413 CC/1=NN(C(=O)\C1=C\c2cccc(OC(=O)c3cccs3)c2)c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L20 compound treatment 279.6 93.3 0.49 286.7 94.9 0.49 0.6928 1.0 1974553 ChemDiv1_009414 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC)c4ccccc34)c(=O)n2C1c5ccc(OC(=O)c6ccco6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L21 compound treatment 277.1 90.8 0.47 286.7 94.9 0.49 0.6836 0.9998 1494030 ChemDiv1_009415 Cc1ccc(cc1)n2ncc3c(Nc4ccc(cc4)S(=O)(=O)N)ncnc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L22 compound treatment 276.6 90.3 0.47 288.7 96.9 0.5 0.6891 0.9994 1682880 ChemDiv1_009416 Clc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L23 mock treatment 275.4 89.1 0.46 282.4 90.6 0.47 0.6615 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 L24 mock treatment 81.5 -105.0 -0.55 81.2 -111.0 -0.58 -0.7932 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M01 compound treatment 278.0 91.7 0.48 289.5 97.7 0.51 0.6972 0.9996 1523724 ChemDiv1_009417 COc1ccc(OC)c(Nc2nc(nc3ccccc23)c4ccccc4O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M02 compound treatment 282.4 96.1 0.5 289.6 97.8 0.51 0.7138 1.0 1974554 ChemDiv1_009418 CCOC(=O)N1CCN(CC1)C(=O)/C(=C\c2cccs2)/NC(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M03 compound treatment 275.5 89.2 0.47 288.6 96.8 0.5 0.6847 0.9992 1974555 ChemDiv1_009419 Cc1cccc(c1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SCC(=O)N)nnc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M04 compound treatment 283.5 97.2 0.51 296.8 105.0 0.55 0.7443 0.9993 1974556 ChemDiv1_009420 COc1ccccc1N2CCN(CC2)C(=O)/C(=C/c3cccnc3)/NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M05 compound treatment 278.2 91.9 0.48 296.1 104.0 0.54 0.7222 0.9981 1502874 ChemDiv1_009421 CCOC(=O)c1c(Cn2ccnc2C)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M06 compound treatment 272.9 86.6 0.45 298.6 107.0 0.55 0.7118 0.9948 1944831 ChemDiv1_009422 Brc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M07 compound treatment 279.9 93.6 0.49 293.4 102.0 0.53 0.7185 0.9992 1703897 ChemDiv1_009423 CCOC(=O)c1c(CN(CC)CC)n(c2ccccc2)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M08 compound treatment 283.8 97.5 0.51 294.5 103.0 0.53 0.737 0.9997 1974557 ChemDiv1_009424 O=C(CSC1=C(C#N)C(CC(=O)N1)c2cccs2)Nc3nccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M09 compound treatment 280.7 94.4 0.49 293.8 102.0 0.53 0.723 0.9993 1974558 ChemDiv1_009425 [O-][N+](=O)c1c(Sc2ncnc3ccccc23)ccc4nsnc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M10 compound treatment 275.8 89.5 0.47 289.7 97.9 0.51 0.6898 0.9991 1974559 ChemDiv1_009426 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(c2)C(=O)C)C#N)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M11 compound treatment 276.8 90.5 0.47 292.3 100.0 0.52 0.7031 0.9987 1398306 ChemDiv1_009427 Cc1c(NC(=O)CSc2nc3ccccc3[nH]2)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M12 compound treatment 276.3 90.0 0.47 291.3 99.5 0.52 0.6976 0.9988 1974560 ChemDiv1_009428 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(cc2)C(=O)C)C#N)c3ccc(cc3)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M13 compound treatment 278.8 92.5 0.48 294.4 103.0 0.53 0.7182 0.9988 1974561 ChemDiv1_009429 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3cc(C)ccc3nc2N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M14 compound treatment 277.0 90.7 0.47 293.6 102.0 0.53 0.7086 0.9985 1974562 ChemDiv1_009430 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3ccc(cc3)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M15 compound treatment 277.0 90.7 0.47 293.3 101.0 0.53 0.7075 0.9985 1974563 ChemDiv1_009431 Cc1ccc(cc1C)c2nn(c3cc(ccc3N4CCCC4)[N+](=O)[O-])c(=O)c5ccccc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M16 compound treatment 279.7 93.4 0.49 292.5 101.0 0.52 0.7145 0.9994 1974564 ChemDiv1_009432 CCc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)C(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M17 compound treatment 280.2 93.9 0.49 293.7 102.0 0.53 0.7208 0.9992 1974565 ChemDiv1_009433 COc1ccc(cc1)C(=O)OCCN2CCN(CC2)C3=NS(=O)(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M18 compound treatment 282.4 96.1 0.5 291.2 99.4 0.52 0.7197 0.9999 1189801 ChemDiv1_009434 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc(C)c2C)C#N)c3ccco3)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M19 compound treatment 276.0 89.7 0.47 283.2 91.4 0.47 0.6667 1.0 1974566 ChemDiv1_009435 Cc1nc(nc(N2CCN(CC2)c3ccccc3)c1[N+](=O)[O-])N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M20 compound treatment 279.0 92.7 0.48 288.3 96.5 0.5 0.6965 0.9998 1717619 ChemDiv1_009436 Clc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M21 compound treatment 278.4 92.1 0.48 285.9 94.1 0.49 0.6854 1.0 1974567 ChemDiv1_009437 Cc1cc(C)n(n1)c2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M22 compound treatment 278.7 92.4 0.48 284.9 93.1 0.48 0.6829 1.0 1974568 ChemDiv1_009438 Cc1ccccc1NC(=O)c2c(C)nc(SCC(=O)N)c(C#N)c2c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M23 mock treatment 281.1 94.8 0.49 282.7 90.9 0.47 0.6836 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 M24 mock treatment 190.4 4.1 0.02 190.6 -1.24 -0.01 0.0106 0.4729 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N01 compound treatment 286.7 100.0 0.52 295.0 103.0 0.54 0.7495 0.9999 1301065 ChemDiv1_009439 CCOc1cc(ccc1OCc2ccc(Cl)cc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N02 compound treatment 285.0 98.7 0.51 289.7 97.9 0.51 0.7238 1.0 1647181 ChemDiv1_009440 Cc1cc(Nc2cccc(F)c2)nc(n1)N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N03 compound treatment 280.0 93.7 0.49 288.0 96.2 0.5 0.6991 0.9999 1974569 ChemDiv1_009441 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4Cl)[N+](=O)[O-])C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N04 compound treatment 282.6 96.3 0.5 293.8 102.0 0.53 0.73 0.9996 1785879 ChemDiv1_009442 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4ccccc4OC(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N05 compound treatment 274.8 88.5 0.46 292.6 101.0 0.52 0.6968 0.998 1974570 ChemDiv1_009443 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4C(F)(F)F)C#N)c(C)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N06 compound treatment 277.7 91.4 0.48 291.5 99.7 0.52 0.7035 0.9991 1974571 ChemDiv1_009444 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccc(F)c(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N07 compound treatment 278.2 91.9 0.48 291.6 99.8 0.52 0.7057 0.9992 1409415 ChemDiv1_009445 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(C)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N08 compound treatment 277.9 91.6 0.48 292.8 101.0 0.52 0.709 0.9989 1673549 ChemDiv1_009446 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(Cn5nnc6ccccc56)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N09 compound treatment 279.0 92.7 0.48 292.6 101.0 0.52 0.7123 0.9992 1974572 ChemDiv1_009447 CC(C)c1cc(C)ccc1OCCSc2nc3c(N)ncnc3[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N10 compound treatment 277.6 91.3 0.48 291.0 99.2 0.52 0.7012 0.9992 1119253 ChemDiv1_009448 C(Nc1nc(Nc2ccc3OCOc3c2)nc(n1)N4CCOCC4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N11 compound treatment 277.9 91.6 0.48 294.1 102.0 0.53 0.7137 0.9986 1400043 ChemDiv1_009449 CC(C)OC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N12 compound treatment 276.4 90.1 0.47 290.9 99.1 0.51 0.6965 0.999 1974573 ChemDiv1_009450 CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N13 compound treatment 280.2 93.9 0.49 288.2 96.4 0.5 0.7005 0.9999 1152030 ChemDiv1_009451 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N14 compound treatment 275.8 89.5 0.47 291.7 99.9 0.52 0.6972 0.9986 1263865 ChemDiv1_009452 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N15 compound treatment 280.2 93.9 0.49 287.7 95.9 0.5 0.6987 1.0 1974574 ChemDiv1_009453 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N16 compound treatment 279.0 92.7 0.48 289.1 97.3 0.51 0.6994 0.9998 1610222 ChemDiv1_009454 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Cl)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N17 compound treatment 277.4 91.1 0.48 290.2 98.4 0.51 0.6976 0.9993 1297670 ChemDiv1_009455 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N18 compound treatment 271.0 84.7 0.44 291.1 99.3 0.52 0.6773 0.997 1340012 ChemDiv1_009456 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3Cl)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N19 compound treatment 280.2 93.9 0.49 287.5 95.7 0.5 0.698 1.0 1974575 ChemDiv1_009457 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cc(ccc2Cl)c3nc4cc(ccc4o3)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N20 compound treatment 276.2 89.9 0.47 283.8 92.0 0.48 0.6696 1.0 1974576 ChemDiv1_009458 CCCN1C(=O)C(=c2sc3=NC(=C(C(c4ccc(OC(=O)c5ccco5)cc4)n3c2=O)C(=O)OCC)C)c6ccccc16 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N21 compound treatment 272.2 85.9 0.45 283.7 91.9 0.48 0.6545 0.9995 1786181 ChemDiv1_009459 COc1ccc(cc1Cn2cc(cn2)[N+](=O)[O-])C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N22 compound treatment 275.7 89.4 0.47 283.8 92.0 0.48 0.6678 0.9999 1412099 ChemDiv1_009460 Cc1cccn2cc(nc12)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N23 mock treatment 276.9 90.6 0.47 287.4 95.6 0.5 0.6854 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 N24 mock treatment 189.2 2.9 0.02 194.4 2.56 0.01 0.0201 0.9979 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O01 compound treatment 284.5 98.2 0.51 289.5 97.7 0.51 0.7212 1.0 1322048 ChemDiv1_009461 COC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccccc4O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O02 compound treatment 282.4 96.1 0.5 288.5 96.7 0.5 0.7098 1.0 1974577 ChemDiv1_009462 OCCN1CCN(CC1)C(=O)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O03 compound treatment 277.4 91.1 0.48 288.4 96.6 0.5 0.6909 0.9996 1592862 ChemDiv1_009463 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SCC(=O)N)nnc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O04 compound treatment 282.8 96.5 0.5 289.4 97.6 0.51 0.7145 1.0 1974578 ChemDiv1_009464 COc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O05 compound treatment 278.3 92.0 0.48 289.0 97.2 0.51 0.6965 0.9997 1424478 ChemDiv1_009465 CCOC(=O)c1c(CNc2ccncc2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O06 compound treatment 277.6 91.3 0.48 289.3 97.5 0.51 0.695 0.9995 1695149 ChemDiv1_009466 COc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O07 compound treatment 283.0 96.7 0.5 290.2 98.4 0.51 0.7182 1.0 1156765 ChemDiv1_009467 CCOC(=O)c1c(CN2CCC(C)CC2)n(c3ccccc3)c4cc(Br)c(OC(=O)C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O08 compound treatment 280.3 94.0 0.49 291.4 99.6 0.52 0.7127 0.9996 1271182 ChemDiv1_009468 Cc1ccc(NC(=O)c2sc3nc4CCCCc4c(c5ccco5)c3c2N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O09 compound treatment 277.4 91.1 0.48 288.4 96.6 0.5 0.6909 0.9996 1634748 ChemDiv1_009469 Cc1nc2ccccc2c3nc(NC(=O)Cc4ccccc4)nn13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O10 compound treatment 277.0 90.7 0.47 290.4 98.6 0.51 0.6968 0.9992 1322509 ChemDiv1_009470 Cc1ccc(C)c(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O11 compound treatment 293.5 107.0 0.56 305.8 114.0 0.59 0.8143 0.9996 1544705 ChemDiv1_009471 CCOC(=O)c1sc(NC(=O)CSc2nc3ccccc3[nH]2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O12 compound treatment 277.7 91.4 0.48 292.5 101.0 0.52 0.7071 0.9989 1359590 ChemDiv1_009472 CCOc1ccc(cc1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccc(NC(=O)C)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O13 compound treatment 276.7 90.4 0.47 294.3 102.0 0.53 0.7101 0.9982 1974579 ChemDiv1_009473 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3cc(C)ccc3nc2N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O14 compound treatment 281.3 95.0 0.5 293.4 102.0 0.53 0.7237 0.9995 1974580 ChemDiv1_009474 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(F)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O15 compound treatment 278.0 91.7 0.48 287.7 95.9 0.5 0.6906 0.9998 1706825 ChemDiv1_009475 CCOC(=O)c1c(CSc2ccccc2)n(C3CCCCC3)c4cc(Br)c(O)c(CN(C)C)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O16 compound treatment 278.5 92.2 0.48 294.4 103.0 0.53 0.7171 0.9987 1974581 ChemDiv1_009476 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O17 compound treatment 278.3 92.0 0.48 288.6 96.8 0.5 0.695 0.9997 1601011 ChemDiv1_009477 OC1(CC=C)C(=O)Nc2ccccc21 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O18 compound treatment 276.2 89.9 0.47 290.2 98.4 0.51 0.6931 0.9991 1384891 ChemDiv1_009478 CC1=C(C(C(=C(N1)SCC(=O)c2ccccc2)C#N)c3ccc(Cl)cc3)C(=O)OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O19 compound treatment 280.6 94.3 0.49 285.2 93.4 0.49 0.691 1.0 1974582 ChemDiv1_009479 CCOc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O20 compound treatment 278.9 92.6 0.48 285.7 93.9 0.49 0.6866 1.0 1366146 ChemDiv1_009480 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O21 compound treatment 278.1 91.8 0.48 284.1 92.3 0.48 0.6777 1.0 1974583 ChemDiv1_009481 Cc1nc(nc(OC2C(=O)c3ccccc3C2=O)c1[N+](=O)[O-])N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O22 compound treatment 276.9 90.6 0.47 282.2 90.4 0.47 0.6663 1.0 1351157 ChemDiv1_009482 CC1=C(C(C(=C(N1)SCc2ccc(Cl)cc2)C#N)c3ccc(Cl)cc3)C(=O)OC(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O23 mock treatment 275.0 88.7 0.46 278.2 86.4 0.45 0.6446 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 O24 mock treatment 87.5 -98.8 -0.52 93.7 -98.1 -0.51 -0.7252 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P01 compound treatment 283.1 96.8 0.5 291.6 99.8 0.52 0.7237 0.9999 1420241 ChemDiv1_009483 CCOc1cc(ccc1OCc2ccc(o2)C(=O)OC)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P02 compound treatment 286.2 99.9 0.52 287.6 95.8 0.5 0.7205 0.9997 1974584 ChemDiv1_009484 Cc1ccc(cc1)n2c(=O)c3c4CC(C)(C)OCc4sc3n5c(SCC(=O)c6ccccc6)nnc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P03 compound treatment 286.7 100.0 0.52 285.8 94.0 0.49 0.7157 0.9994 1974585 ChemDiv1_009485 Cc1sccc1C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4Cl)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P04 compound treatment 285.8 99.5 0.52 291.3 99.5 0.52 0.7326 1.0 1974586 ChemDiv1_009486 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc5OCOc5c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P05 compound treatment 285.3 99.0 0.52 293.3 101.0 0.53 0.7381 0.9999 1974587 ChemDiv1_009487 CSc1sc(C)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P06 compound treatment 286.0 99.7 0.52 291.3 99.5 0.52 0.7333 1.0 1974588 ChemDiv1_009488 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P07 compound treatment 276.7 90.4 0.47 291.3 99.5 0.52 0.699 0.9989 1974589 ChemDiv1_009489 CSc1sc(C)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P08 compound treatment 281.0 94.7 0.49 291.4 99.6 0.52 0.7153 0.9997 1410018 ChemDiv1_009490 COc1cc(cc(OC)c1OC)C2Nc3ccccc3C(=O)N2c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P09 compound treatment 284.6 98.3 0.51 295.6 104.0 0.54 0.744 0.9997 1444995 ChemDiv1_009491 Nc1ncnc2[nH]c(SCC(=O)Nc3ccc(Cl)cc3)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P10 compound treatment 277.5 91.2 0.48 292.3 100.0 0.52 0.7057 0.9989 1421045 ChemDiv1_009492 CCOc1nc(NCc2ccccc2)nc(NCc3cccnc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P11 compound treatment 276.2 89.9 0.47 282.4 90.6 0.47 0.6645 1.0 1871229 ChemDiv1_009493 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P12 compound treatment 276.2 89.9 0.47 289.8 98.0 0.51 0.6917 0.9992 1974590 ChemDiv1_009494 CC1=C(C(NC(=O)N1)c2ccccc2)C(=O)Nc3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P13 compound treatment 275.4 89.1 0.46 286.3 94.5 0.49 0.6759 0.9996 1871384 ChemDiv1_009495 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P14 compound treatment 279.1 92.8 0.48 292.9 101.0 0.53 0.7138 0.9992 1201246 ChemDiv1_009496 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)ccc3OC)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P15 compound treatment 276.6 90.3 0.47 292.7 101.0 0.52 0.7038 0.9986 1500676 ChemDiv1_009497 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P16 compound treatment 282.3 96.0 0.5 294.3 102.0 0.53 0.7307 0.9995 1926432 ChemDiv1_009498 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P17 compound treatment 282.0 95.7 0.5 290.2 98.4 0.51 0.7145 0.9999 1974591 ChemDiv1_009499 COCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P18 compound treatment 277.1 90.8 0.47 292.4 101.0 0.52 0.7045 0.9988 1607092 ChemDiv1_009500 COc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)Nc3ccccc3Cl)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P19 compound treatment 274.9 88.6 0.46 287.8 96.0 0.5 0.6795 0.9993 1291364 ChemDiv1_009501 COc1cc(cc(OC)c1OC)C(=O)Nc2cc(ccc2Cl)c3nc4cc(ccc4o3)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P20 compound treatment 273.8 87.5 0.46 287.2 95.4 0.5 0.6733 0.9992 1974592 ChemDiv1_009502 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC=C)c4ccccc34)c(=O)n2C1c5ccc(OC(=O)c6ccco6)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P21 compound treatment 277.4 91.1 0.48 286.4 94.6 0.49 0.6836 0.9999 1974593 ChemDiv1_009503 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(Cn5cc(cn5)[N+](=O)[O-])c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P22 compound treatment 278.4 92.1 0.48 284.0 92.2 0.48 0.6785 1.0 1631623 ChemDiv1_009504 Cc1ccn2cc(nc2c1)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P23 mock treatment 280.3 94.0 0.49 286.8 95.0 0.49 0.6958 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.613 P24 mock treatment 92.9 -93.4 -0.49 98.5 -93.3 -0.49 -0.6876 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A01 compound treatment 286.1 100.0 0.52 290.5 100.0 0.52 0.7374 1.0 1293447 ChemDiv1_009505 Clc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A02 compound treatment 286.8 101.0 0.53 289.9 99.4 0.52 0.7377 1.0 1864033 ChemDiv1_009506 COc1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A03 compound treatment 282.1 96.3 0.5 289.1 98.6 0.51 0.7175 0.9999 1974594 ChemDiv1_009507 Clc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A04 compound treatment 281.4 95.6 0.5 290.9 100.0 0.52 0.7215 0.9997 1864046 ChemDiv1_009508 [O-][N+](=O)c1ccc(cc1)c2nc(NC3CCCCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A05 compound treatment 277.6 91.8 0.48 290.7 100.0 0.52 0.7067 0.9991 1974595 ChemDiv1_009509 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A06 compound treatment 280.1 94.3 0.49 292.0 101.0 0.53 0.7207 0.9994 1974596 ChemDiv1_009510 [O-][N+](=O)c1ccc(cc1)c2nc(NCCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A07 compound treatment 280.3 94.5 0.49 291.1 101.0 0.52 0.7182 0.9996 1974597 ChemDiv1_009511 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3ccc(F)cc3)c4ccccc24)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A08 compound treatment 275.2 89.4 0.47 290.8 100.0 0.52 0.6983 0.9984 1864072 ChemDiv1_009512 [O-][N+](=O)c1ccc(cc1)c2nc(N3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A09 compound treatment 277.4 91.6 0.48 291.9 101.0 0.53 0.7104 0.9988 1974598 ChemDiv1_009513 CC1CN(CC(C)O1)C2=NC(=O)/C(=C\3/C(=O)N(CC=C)c4ccc(Br)cc34)/S2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A10 compound treatment 273.4 87.6 0.46 289.6 99.1 0.52 0.6872 0.9982 1504779 ChemDiv1_009514 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A11 compound treatment 294.7 109.0 0.57 302.9 112.0 0.58 0.8147 0.9999 1974599 ChemDiv1_009515 Cc1ccc(CN2C(=O)/C(=C/3\SC(=S)N(CCS(=O)(=O)O)C3=O)/c4cc(Br)ccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A12 compound treatment 280.5 94.7 0.49 290.8 100.0 0.52 0.7178 0.9996 1974600 ChemDiv1_009516 CCOc1cc(/C=C\2/NC(=O)NC2=O)cc(Br)c1OCC#C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A13 compound treatment 268.5 82.7 0.43 291.8 101.0 0.53 0.6772 0.9951 1142666 ChemDiv1_009517 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(OC)c3)c4ccccc4)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A14 compound treatment 274.8 89.0 0.46 291.5 101.0 0.52 0.6994 0.9981 1644663 ChemDiv1_009518 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc5CCCCc5cc4c3N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A15 compound treatment 276.7 90.9 0.47 291.5 101.0 0.52 0.7064 0.9987 1394660 ChemDiv1_009519 COc1ccc(cc1Br)c2cn3cccc(C)c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A16 compound treatment 283.4 97.6 0.51 292.0 101.0 0.53 0.7329 0.9998 1974601 ChemDiv1_009520 OC(=O)c1ccc(cc1Cl)c2ccc(/C=C/3\NC(=O)N(Cc4ccc(Cl)cc4)C3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A17 compound treatment 273.0 87.2 0.45 279.5 89.0 0.46 0.6486 1.0 1627312 ChemDiv1_009521 O=C(Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A18 compound treatment 277.6 91.8 0.48 285.4 94.9 0.49 0.6873 0.9999 1246856 ChemDiv1_009522 C1CCN(CC1)c2nc(nc(n2)N3CCNCC3)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A19 compound treatment 273.8 88.0 0.46 286.7 96.2 0.5 0.678 0.9991 1524561 ChemDiv1_009523 CCOC(=O)c1c(C)oc2ccc(OCc3c(OC)ccc4cc(Br)ccc34)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A20 compound treatment 275.9 90.1 0.47 282.5 92.0 0.48 0.6703 1.0 1307670 ChemDiv1_009524 COCc1cc(C)nc2sc(C(=O)Nc3ccc(Br)c(Cl)c3)c(N)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A21 compound treatment 277.4 91.6 0.48 282.8 92.3 0.48 0.677 1.0 1974602 ChemDiv1_009525 COCCN(CCOC)c1nc(nc2ccccc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A22 compound treatment 276.7 90.9 0.47 283.0 92.5 0.48 0.6751 1.0 1358341 ChemDiv1_009526 CCS(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A23 mock treatment 279.0 93.2 0.49 284.1 93.6 0.49 0.6876 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 A24 mock treatment 81.6 -104.0 -0.54 80.2 -110.0 -0.57 -0.7899 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B01 compound treatment 280.6 94.8 0.49 292.3 102.0 0.53 0.7237 0.9994 1577370 ChemDiv1_009527 Nc1nc(CSc2nc3ccccc3s2)nc(n1)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B02 compound treatment 284.5 98.7 0.51 288.2 97.7 0.51 0.723 1.0 1852878 ChemDiv1_009528 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(SC)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B03 compound treatment 283.2 97.4 0.51 292.3 102.0 0.53 0.7333 0.9998 1974603 ChemDiv1_009529 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B04 compound treatment 283.1 97.3 0.51 293.5 103.0 0.54 0.7373 0.9996 1852886 ChemDiv1_009530 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Br)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B05 compound treatment 282.0 96.2 0.5 291.6 101.0 0.53 0.7263 0.9997 1545122 ChemDiv1_009531 CC1CCc2c(C1)sc3[nH]c(=S)[nH]c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B06 compound treatment 275.1 89.3 0.47 298.4 108.0 0.56 0.7258 0.9957 1852890 ChemDiv1_009532 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccsc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B07 compound treatment 276.6 90.8 0.47 296.7 106.0 0.55 0.7251 0.9971 1219251 ChemDiv1_009533 CCOc1ccc(cc1Br)C(=O)Nc2cccc(c2)c3nc4cc(C)cc(C)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B08 compound treatment 277.3 91.5 0.48 285.4 94.9 0.49 0.6862 0.9999 1853085 ChemDiv1_009534 COc1cc(cc(OC)c1OC)C2C(=C(N)N(N(C)C)C3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B09 compound treatment 275.2 89.4 0.47 293.4 103.0 0.53 0.7078 0.9977 1663826 ChemDiv1_009535 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)ccc3OC)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B10 compound treatment 277.2 91.4 0.48 292.0 101.0 0.53 0.71 0.9987 1974604 ChemDiv1_009536 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccccc3C)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B11 compound treatment 280.1 94.3 0.49 294.5 104.0 0.54 0.7299 0.9989 1461697 ChemDiv1_009537 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3OC)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B12 compound treatment 275.3 89.5 0.47 290.4 99.9 0.52 0.6972 0.9986 1241988 ChemDiv1_009538 Clc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B13 compound treatment 278.2 92.4 0.48 289.0 98.5 0.51 0.7027 0.9995 1631740 ChemDiv1_009539 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(C)C)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B14 compound treatment 277.8 92.0 0.48 289.3 98.8 0.51 0.7023 0.9994 1628280 ChemDiv1_009540 Clc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B15 compound treatment 276.5 90.7 0.47 284.8 94.3 0.49 0.681 0.9998 1852843 ChemDiv1_009541 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Cl)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B16 compound treatment 280.3 94.5 0.49 290.3 99.8 0.52 0.7152 0.9997 1275882 ChemDiv1_009542 COc1ccccc1Nc2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B17 compound treatment 279.6 93.8 0.49 284.5 94.0 0.49 0.6913 1.0 1852850 ChemDiv1_009543 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3C)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B18 compound treatment 274.0 88.2 0.46 286.6 96.1 0.5 0.6784 0.9991 1974605 ChemDiv1_009544 Cc1sc2ncnc(SCC(=O)Nc3ccc(Br)cc3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B19 compound treatment 272.8 87.0 0.45 284.6 94.1 0.49 0.6666 0.9993 1852857 ChemDiv1_009545 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(O)c(OC)c3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B20 compound treatment 277.8 92.0 0.48 283.2 92.7 0.48 0.6799 1.0 1136198 ChemDiv1_009546 Cc1ccc(OCCn2c(S)nc3c(N)ncnc23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B21 compound treatment 277.2 91.4 0.48 285.3 94.8 0.49 0.6854 0.9999 1460446 ChemDiv1_009547 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccs3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B22 compound treatment 273.2 87.4 0.46 281.1 90.6 0.47 0.6552 0.9999 1974606 ChemDiv1_009548 CCOc1ccc2[nH]c3nc4ccccc4nc3c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B23 mock treatment 276.2 90.4 0.47 287.8 97.3 0.51 0.6909 0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 B24 mock treatment 77.9 -108.0 -0.56 80.5 -110.0 -0.57 -0.8025 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C01 compound treatment 289.1 103.0 0.54 294.2 104.0 0.54 0.762 1.0 1338440 ChemDiv1_009549 CN(C)S(=O)(=O)c1ccc(cc1)c2cn3cccc(C)c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C02 compound treatment 282.8 97.0 0.51 291.4 101.0 0.52 0.7285 0.9998 1864034 ChemDiv1_009550 COc1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C03 compound treatment 281.5 95.7 0.5 293.3 103.0 0.53 0.7307 0.9994 1974607 ChemDiv1_009551 OC(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(Cl)c3)c4ccccc24)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C04 compound treatment 278.9 93.1 0.49 289.5 99.0 0.51 0.7071 0.9996 1864048 ChemDiv1_009552 CC(Nc1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-])c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C05 compound treatment 282.8 97.0 0.51 292.6 102.0 0.53 0.7329 0.9997 1974608 ChemDiv1_009553 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CCS(=O)(=O)O)C3=O)/c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C06 compound treatment 279.0 93.2 0.49 292.7 102.0 0.53 0.7193 0.999 1864059 ChemDiv1_009554 CCCCN(C)c1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C07 compound treatment 283.0 97.2 0.51 293.7 103.0 0.54 0.7377 0.9996 1974609 ChemDiv1_009555 Clc1ccc(cc1)c2c(OC(=O)CCN3C(=O)/C(=C\c4ccccc4)/SC3=S)ccc5oc(=O)sc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C08 compound treatment 273.6 87.8 0.46 292.4 102.0 0.53 0.6982 0.9974 1864073 ChemDiv1_009556 CC1CN(CC(C)O1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C09 compound treatment 316.5 131.0 0.68 334.8 144.0 0.75 1.0123 0.9989 1974610 ChemDiv1_009557 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(Cc3ccccc3)c4ccc(Br)cc24)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C10 compound treatment 274.2 88.4 0.46 289.1 98.6 0.51 0.6883 0.9986 1974611 ChemDiv1_009558 CS(=O)(=O)c1cc([N+](=O)[O-])c(Sc2nc3ccccc3s2)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C11 compound treatment 282.1 96.3 0.5 295.1 105.0 0.54 0.7395 0.9992 1974612 ChemDiv1_009559 Cc1ccc(CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5cc(Br)ccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C12 compound treatment 277.5 91.7 0.48 288.0 97.5 0.51 0.6964 0.9996 1488977 ChemDiv1_009560 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3nnc(s3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C13 compound treatment 274.5 88.7 0.46 290.1 99.6 0.52 0.6931 0.9984 1464415 ChemDiv1_009561 Cc1c(oc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C14 compound treatment 276.6 90.8 0.47 289.0 98.5 0.51 0.6968 0.9992 1420115 ChemDiv1_009562 CCc1nnc(NC(=O)c2sc3nc4CCCCCc4cc3c2N)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C15 compound treatment 275.1 89.3 0.47 291.3 101.0 0.52 0.6997 0.9983 1518928 ChemDiv1_009563 COc1ccc(cc1Br)c2cn3ccc(C)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C16 compound treatment 275.5 89.7 0.47 288.5 98.0 0.51 0.6909 0.9991 1974613 ChemDiv1_009564 COC(=O)Cn1cc(/C=C/2\NC(=O)N(Cc3ccc(Cl)cc3)C2=O)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C17 compound treatment 276.9 91.1 0.48 285.6 95.1 0.49 0.6854 0.9998 1925232 ChemDiv1_009565 [O-][N+](=O)c1ccc(COc2ccc3c(=O)c(coc3c2)c4nc5ccccc5s4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C18 compound treatment 296.1 110.0 0.58 305.9 115.0 0.6 0.8308 0.9998 1160847 ChemDiv1_009566 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)cc3OC)c(=O)n2C1c4ccc(cc4)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C19 compound treatment 277.4 91.6 0.48 283.4 92.9 0.48 0.6792 1.0 1974614 ChemDiv1_009567 CCOC(=O)c1c(oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C20 compound treatment 273.6 87.8 0.46 288.8 98.3 0.51 0.685 0.9985 1974615 ChemDiv1_009568 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCC(=O)Nc4ccc(Br)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C21 compound treatment 275.9 90.1 0.47 285.3 94.8 0.49 0.6806 0.9997 1974616 ChemDiv1_009569 Cc1ccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C22 compound treatment 275.5 89.7 0.47 281.2 90.7 0.47 0.6641 1.0 1974617 ChemDiv1_009570 CCS(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C23 mock treatment 277.2 91.4 0.48 283.6 93.1 0.48 0.6792 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 C24 mock treatment 78.0 -108.0 -0.56 84.0 -107.0 -0.55 -0.7893 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D01 compound treatment 283.4 97.6 0.51 292.0 101.0 0.53 0.7329 0.9998 1974618 ChemDiv1_009571 CCCCCCN(Cc1ccco1)c2nc(nc(n2)N3CCOCC3)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D02 compound treatment 280.6 94.8 0.49 291.9 101.0 0.53 0.7222 0.9995 1852879 ChemDiv1_009572 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3sccc3C)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D03 compound treatment 280.1 94.3 0.49 290.3 99.8 0.52 0.7145 0.9996 1396898 ChemDiv1_009573 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D04 compound treatment 281.0 95.2 0.5 294.8 104.0 0.54 0.7344 0.999 1852887 ChemDiv1_009574 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Br)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D05 compound treatment 304.7 119.0 0.62 318.1 128.0 0.66 0.9074 0.9994 1974619 ChemDiv1_009575 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)[N+](=O)[O-])c(=O)n2C1c4ccccc4OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D06 compound treatment 309.0 123.0 0.64 315.5 125.0 0.65 0.9137 1.0 1452712 ChemDiv1_009576 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccsc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D07 compound treatment 275.3 89.5 0.47 290.8 100.0 0.52 0.6986 0.9985 1140770 ChemDiv1_009577 COc1ccc(Br)cc1C(=O)Nc2cc(ccc2C)c3nc4cc(C)cc(C)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D08 compound treatment 280.3 94.5 0.49 294.6 104.0 0.54 0.731 0.9989 1683511 ChemDiv1_009578 COc1ccc(cc1OC)C2C(=C(N)N(N(C)C)C3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D09 compound treatment 277.0 91.2 0.48 291.3 101.0 0.52 0.7067 0.9988 1852820 ChemDiv1_009579 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)c(OC)c(OC)c3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D10 compound treatment 274.7 88.9 0.46 293.0 102.0 0.53 0.7045 0.9976 1974620 ChemDiv1_009580 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3cccc(C)c3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D11 compound treatment 277.6 91.8 0.48 289.0 98.5 0.51 0.7005 0.9994 1852826 ChemDiv1_009581 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3OC)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D12 compound treatment 270.7 84.9 0.44 291.7 101.0 0.53 0.685 0.9963 1609272 ChemDiv1_009582 COc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D13 compound treatment 277.6 91.8 0.48 290.6 100.0 0.52 0.7064 0.9991 1852837 ChemDiv1_009583 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(C)C)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D14 compound treatment 277.0 91.2 0.48 292.5 102.0 0.53 0.7111 0.9985 1623340 ChemDiv1_009584 Brc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D15 compound treatment 275.9 90.1 0.47 291.2 101.0 0.52 0.7023 0.9985 1852844 ChemDiv1_009585 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D16 compound treatment 276.7 90.9 0.47 292.2 102.0 0.53 0.7089 0.9985 1387715 ChemDiv1_009586 C(Nc1nc(nc2ccccc12)N3CCN(Cc4ccccc4)CC3)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D17 compound treatment 276.4 90.6 0.47 291.3 101.0 0.52 0.7045 0.9987 1852852 ChemDiv1_009587 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3OC)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D18 compound treatment 276.4 90.6 0.47 288.7 98.2 0.51 0.695 0.9993 1293891 ChemDiv1_009588 CCOc1ccc(Cc2nnc(S)o2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D19 compound treatment 277.2 91.4 0.48 288.9 98.4 0.51 0.6986 0.9994 1852858 ChemDiv1_009589 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(O)c(OC)c3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D20 compound treatment 278.7 92.9 0.48 285.5 95.0 0.49 0.6917 1.0 1713647 ChemDiv1_009590 COc1ccc(Br)cc1C(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D21 compound treatment 276.4 90.6 0.47 281.2 90.7 0.47 0.6674 1.0 1647959 ChemDiv1_009591 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccs3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D22 compound treatment 273.9 88.1 0.46 288.8 98.3 0.51 0.6861 0.9986 1974621 ChemDiv1_009592 C(Sc1nnc(o1)c2ccco2)c3nc4ccccc4[nH]3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D23 mock treatment 275.7 89.9 0.47 285.9 95.4 0.5 0.6821 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 D24 mock treatment 79.6 -106.0 -0.55 79.3 -111.0 -0.58 -0.8006 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E01 compound treatment 287.6 102.0 0.53 293.0 102.0 0.53 0.7521 1.0 1437406 ChemDiv1_009593 CN(C)S(=O)(=O)c1ccc(cc1)c2cn3cc(Cl)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E02 compound treatment 283.0 97.2 0.51 290.8 100.0 0.52 0.727 0.9999 1864039 ChemDiv1_009594 COC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E03 compound treatment 279.9 94.1 0.49 295.4 105.0 0.55 0.7325 0.9986 1974622 ChemDiv1_009595 Brc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E04 compound treatment 284.0 98.2 0.51 294.4 104.0 0.54 0.7439 0.9996 1864049 ChemDiv1_009596 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E05 compound treatment 288.7 103.0 0.54 295.3 105.0 0.54 0.7646 1.0 1974623 ChemDiv1_009597 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CCC(=O)O)C3=O)/c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E06 compound treatment 280.6 94.8 0.49 297.4 107.0 0.56 0.7424 0.9983 1864062 ChemDiv1_009598 [O-][N+](=O)c1ccc(cc1)c2nc(N(CC=C)CC=C)c3ccccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E07 compound treatment 278.7 92.9 0.48 295.3 105.0 0.54 0.7277 0.9983 1974624 ChemDiv1_009599 COc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E08 compound treatment 278.3 92.5 0.48 294.2 104.0 0.54 0.7222 0.9985 1864074 ChemDiv1_009600 CN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E09 compound treatment 288.1 102.0 0.53 299.9 109.0 0.57 0.7793 0.9995 1974625 ChemDiv1_009601 OC(=O)CN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E10 compound treatment 276.7 90.9 0.47 298.0 107.0 0.56 0.7303 0.9966 1556877 ChemDiv1_009602 CCc1ccc(NC(=O)Cn2cnc(SCc3ccccc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E11 compound treatment 281.1 95.3 0.5 294.0 103.0 0.54 0.7318 0.9992 1218295 ChemDiv1_009603 Cc1cc(C)c(OCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E12 compound treatment 301.8 116.0 0.6 320.7 130.0 0.68 0.9063 0.9984 1974626 ChemDiv1_009604 CCc1nnc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4ccccc4)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E13 compound treatment 280.7 94.9 0.49 291.7 101.0 0.53 0.7219 0.9995 1731593 ChemDiv1_009605 Cc1cccn2cc(nc12)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E14 compound treatment 277.9 92.1 0.48 292.1 102.0 0.53 0.713 0.9989 1421323 ChemDiv1_009606 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Br)o3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E15 compound treatment 278.2 92.4 0.48 287.6 97.1 0.5 0.6976 0.9997 1713093 ChemDiv1_009607 COc1ccc(cc1Br)c2cn3cc(C)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E16 compound treatment 279.4 93.6 0.49 292.6 102.0 0.53 0.7204 0.9991 1974627 ChemDiv1_009608 Cc1cc(/C=C/2\NC(=O)N(Cc3ccc(Cl)cc3)C2=O)c(C)n1c4cc(C)ccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E17 compound treatment 277.9 92.1 0.48 288.8 98.3 0.51 0.7009 0.9995 1364315 ChemDiv1_009609 CCOC(=O)c1c(oc2ccc(OC(=O)c3cc4ccccc4o3)cc12)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E18 compound treatment 316.4 131.0 0.68 323.0 132.0 0.69 0.9686 1.0 1469701 ChemDiv1_009610 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(C)n(C)c3C)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E19 compound treatment 277.1 91.3 0.48 285.5 95.0 0.49 0.6858 0.9998 1439334 ChemDiv1_009611 Clc1cccc(COc2ccc3cc(c4nc5ccccc5s4)c(=O)oc3c2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E20 compound treatment 276.7 90.9 0.47 287.3 96.8 0.5 0.6909 0.9996 1974628 ChemDiv1_009612 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)Cc2ccccc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E21 compound treatment 275.9 90.1 0.47 284.1 93.6 0.49 0.6762 0.9998 1974629 ChemDiv1_009613 CCc1ccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E22 compound treatment 275.5 89.7 0.47 284.5 94.0 0.49 0.6762 0.9998 1974630 ChemDiv1_009614 CCS(=O)(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E23 mock treatment 282.0 96.2 0.5 285.0 94.5 0.49 0.702 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 E24 mock treatment 83.7 -102.0 -0.53 82.5 -108.0 -0.56 -0.7737 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F01 compound treatment 284.6 98.8 0.52 292.4 102.0 0.53 0.7388 0.9999 1621170 ChemDiv1_009615 COc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)Nc3ccc(F)c(F)c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F02 compound treatment 282.1 96.3 0.5 297.2 107.0 0.55 0.7472 0.9988 1852880 ChemDiv1_009616 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3sccc3C)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F03 compound treatment 283.9 98.1 0.51 294.4 104.0 0.54 0.7436 0.9996 1239070 ChemDiv1_009617 NC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F04 compound treatment 280.7 94.9 0.49 295.2 105.0 0.54 0.7347 0.9989 1470920 ChemDiv1_009618 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc4OCOc4c3)C1=O)c5ccccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F05 compound treatment 277.2 91.4 0.48 293.9 103.0 0.54 0.717 0.9982 1947100 ChemDiv1_009619 OC1=C(C(N(C1=O)c2nc3ccccc3s2)c4cccc(c4)[N+](=O)[O-])C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F06 compound treatment 281.8 96.0 0.5 297.8 107.0 0.56 0.7483 0.9985 1612061 ChemDiv1_009620 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccsc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F07 compound treatment 279.9 94.1 0.49 296.6 106.0 0.55 0.7369 0.9983 1437574 ChemDiv1_009621 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)c3nc4cc(Cl)cc(Cl)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F08 compound treatment 277.5 91.7 0.48 297.7 107.0 0.56 0.7321 0.9971 1974631 ChemDiv1_009622 [O-][N+](=O)c1ccccc1NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2CC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F09 compound treatment 279.8 94.0 0.49 294.8 104.0 0.54 0.7299 0.9987 1852821 ChemDiv1_009623 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)c(OC)c(OC)c3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F10 compound treatment 280.7 94.9 0.49 299.7 109.0 0.57 0.7513 0.9977 1974632 ChemDiv1_009624 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccccc3Cl)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F11 compound treatment 273.9 88.1 0.46 294.3 104.0 0.54 0.7063 0.9968 1852830 ChemDiv1_009625 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3OC)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F12 compound treatment 273.9 88.1 0.46 294.4 104.0 0.54 0.7067 0.9968 1236128 ChemDiv1_009626 CCOc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F13 compound treatment 274.3 88.5 0.46 292.9 102.0 0.53 0.7027 0.9975 1852838 ChemDiv1_009627 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(C)C)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F14 compound treatment 279.6 93.8 0.49 292.6 102.0 0.53 0.7211 0.9992 1677893 ChemDiv1_009628 Fc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F15 compound treatment 276.2 90.4 0.47 292.7 102.0 0.53 0.7089 0.9982 1441261 ChemDiv1_009629 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F16 compound treatment 278.4 92.6 0.48 292.0 101.0 0.53 0.7145 0.999 1382426 ChemDiv1_009630 C(Nc1nc(nc2ccccc12)N3CCN(CC3)c4ccccc4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F17 compound treatment 273.6 87.8 0.46 291.7 101.0 0.53 0.6957 0.9976 1209943 ChemDiv1_009631 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3OC)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F18 compound treatment 285.0 99.2 0.52 294.6 104.0 0.54 0.7484 0.9997 1974633 ChemDiv1_009632 CCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/NC(=S)NC3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F19 compound treatment 274.8 89.0 0.46 289.0 98.5 0.51 0.6902 0.9988 1852862 ChemDiv1_009633 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(F)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F20 compound treatment 278.6 92.8 0.48 288.3 97.8 0.51 0.7016 0.9997 1611495 ChemDiv1_009634 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cc(ccc2Cl)c3nc4cc(C)ccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F21 compound treatment 278.6 92.8 0.48 287.1 96.6 0.5 0.6972 0.9998 1475081 ChemDiv1_009635 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccs3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F22 compound treatment 277.0 91.2 0.48 281.9 91.4 0.48 0.6722 1.0 1974634 ChemDiv1_009636 Brc1ccc(cc1)C(=O)CSc2nnc(c3cccnc3)n2Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F23 mock treatment 274.3 88.5 0.46 286.8 96.3 0.5 0.6802 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 F24 mock treatment 78.1 -108.0 -0.56 84.8 -106.0 -0.55 -0.786 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G01 compound treatment 282.1 96.3 0.5 299.5 109.0 0.57 0.7557 0.9982 1610349 ChemDiv1_009637 Cc1cccn2cc(nc12)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G02 compound treatment 279.8 94.0 0.49 294.7 104.0 0.54 0.7296 0.9988 1874117 ChemDiv1_009638 COC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G03 compound treatment 281.6 95.8 0.5 294.1 104.0 0.54 0.734 0.9993 1974635 ChemDiv1_009639 Brc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G04 compound treatment 280.2 94.4 0.49 291.8 101.0 0.53 0.7204 0.9994 1864051 ChemDiv1_009640 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G05 compound treatment 282.8 97.0 0.51 297.9 107.0 0.56 0.7524 0.9988 1974636 ChemDiv1_009641 FC(F)(F)c1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G06 compound treatment 279.1 93.3 0.49 293.1 103.0 0.53 0.7211 0.999 1974637 ChemDiv1_009642 COCCN(CCOC)c1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G07 compound treatment 280.6 94.8 0.49 299.3 109.0 0.57 0.7494 0.9978 1974638 ChemDiv1_009643 COc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G08 compound treatment 280.2 94.4 0.49 298.3 108.0 0.56 0.7443 0.9979 1864075 ChemDiv1_009644 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G09 compound treatment 281.0 95.2 0.5 294.6 104.0 0.54 0.7336 0.9991 1974639 ChemDiv1_009645 OC(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G10 compound treatment 278.9 93.1 0.49 296.5 106.0 0.55 0.7329 0.998 1686350 ChemDiv1_009646 COC(=O)c1ccccc1NC(=O)Cn2c(SCc3ccccc3)nc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G11 compound treatment 271.7 85.9 0.45 294.9 104.0 0.54 0.7004 0.9955 1236222 ChemDiv1_009647 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3cccc(C)c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G12 compound treatment 287.8 102.0 0.53 295.7 105.0 0.55 0.7627 0.9999 1974640 ChemDiv1_009648 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc(cc(c4c3N)C(F)(F)F)c5ccccc5)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G13 compound treatment 279.9 94.1 0.49 294.7 104.0 0.54 0.7299 0.9988 1687733 ChemDiv1_009649 COc1ccc(cc1F)c2cn3ccccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G14 compound treatment 274.3 88.5 0.46 296.5 106.0 0.55 0.7159 0.9961 1974641 ChemDiv1_009650 CCc1ccc(cc1)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G15 compound treatment 278.0 92.2 0.48 287.9 97.4 0.51 0.6979 0.9997 1191057 ChemDiv1_009651 COc1ccc(cc1Br)c2cn3cc(Cl)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G16 compound treatment 291.0 105.0 0.55 300.9 110.0 0.57 0.7937 0.9997 1974642 ChemDiv1_009652 [O-][N+](=O)c1ccc(c2ccc(/C=C\3/NC(=O)N(Cc4ccc(Cl)cc4)C3=O)o2)c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G17 compound treatment 274.8 89.0 0.46 291.3 101.0 0.52 0.6986 0.9982 1555311 ChemDiv1_009653 CCOC(=O)c1c(oc2ccc(OC(=O)c3ccccc3OC)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G18 compound treatment 343.2 157.0 0.82 340.0 149.0 0.78 1.1299 0.9996 1164078 ChemDiv1_009654 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(C)n(C)c3C)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G19 compound treatment 280.1 94.3 0.49 291.3 101.0 0.52 0.7182 0.9995 1974643 ChemDiv1_009655 CN(C)c1ccc(/C=C\2/C(=NN(C2=O)c3ccc(Br)cc3)C)cc1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G20 compound treatment 279.2 93.4 0.49 286.7 96.2 0.5 0.6979 0.9999 1974644 ChemDiv1_009656 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G21 compound treatment 276.6 90.8 0.47 288.8 98.3 0.51 0.6961 0.9993 1974645 ChemDiv1_009657 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CCCOc3ccc(Cl)cc3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G22 compound treatment 275.3 89.5 0.47 284.0 93.5 0.49 0.6736 0.9998 1974646 ChemDiv1_009658 CS(=O)(=O)c1sc2nc(cc(c3ccccc3)c2c1N)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G23 mock treatment 281.5 95.7 0.5 283.8 93.3 0.48 0.6958 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 G24 mock treatment 77.5 -108.0 -0.57 80.8 -110.0 -0.57 -0.8029 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H01 compound treatment 282.8 97.0 0.51 294.1 104.0 0.54 0.7384 0.9995 1685082 ChemDiv1_009659 COc1ccc(C2NC(=O)NC(=C2C(=O)Nc3ccc(F)c(F)c3)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H02 compound treatment 283.6 97.8 0.51 291.4 101.0 0.52 0.7314 0.9999 1852881 ChemDiv1_009660 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3sccc3C)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H03 compound treatment 282.6 96.8 0.5 288.4 97.9 0.51 0.7167 1.0 1974647 ChemDiv1_009661 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H04 compound treatment 280.0 94.2 0.49 294.1 104.0 0.54 0.7281 0.9989 1254487 ChemDiv1_009662 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc4OCOc4c3)C1=O)c5cccc(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H05 compound treatment 279.1 93.3 0.49 294.8 104.0 0.54 0.7273 0.9985 1785887 ChemDiv1_009663 OC1=C(C(N(C1=O)c2nc3ccccc3s2)c4ccc5OCOc5c4)C(=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H06 compound treatment 279.5 93.7 0.49 298.2 108.0 0.56 0.7413 0.9977 1852906 ChemDiv1_009664 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(C)sc3C)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H07 compound treatment 277.3 91.5 0.48 294.7 104.0 0.54 0.7203 0.998 1572697 ChemDiv1_009665 CCOc1ccc(cc1Cl)C(=O)Nc2ccc(cc2)c3nc4cc(C)cc(C)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H08 compound treatment 281.4 95.6 0.5 298.7 108.0 0.56 0.7502 0.9982 1974648 ChemDiv1_009666 CCc1cc2c(=O)n(CC=C)c(SCC(=O)c3ccc(OC)cc3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H09 compound treatment 281.9 96.1 0.5 297.5 107.0 0.56 0.7476 0.9986 1852822 ChemDiv1_009667 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)c(OC)c(OC)c3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H10 compound treatment 277.2 91.4 0.48 296.2 106.0 0.55 0.7255 0.9975 1974649 ChemDiv1_009668 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3cccc(Cl)c3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H11 compound treatment 277.6 91.8 0.48 300.5 110.0 0.57 0.7428 0.9961 1678038 ChemDiv1_009669 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3OC)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H12 compound treatment 276.6 90.8 0.47 294.8 104.0 0.54 0.7181 0.9977 1573809 ChemDiv1_009670 CCOc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCCc4c3c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H13 compound treatment 275.6 89.8 0.47 291.6 101.0 0.53 0.7027 0.9983 1852839 ChemDiv1_009671 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)c(OC)c3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H14 compound treatment 277.1 91.3 0.48 294.3 104.0 0.54 0.7181 0.9981 1606595 ChemDiv1_009672 Cc1ccc(C)c(Nc2nc(NCc3ccco3)c4ccccc4n2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H15 compound treatment 278.8 93.0 0.48 293.7 103.0 0.54 0.7222 0.9987 1852845 ChemDiv1_009673 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H16 compound treatment 275.5 89.7 0.47 290.6 100.0 0.52 0.6986 0.9986 1556983 ChemDiv1_009674 OCCN1CCN(CC1)c2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H17 compound treatment 276.6 90.8 0.47 296.1 106.0 0.55 0.7229 0.9973 1196159 ChemDiv1_009675 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3OC)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H18 compound treatment 275.4 89.6 0.47 290.9 100.0 0.52 0.6994 0.9985 1974650 ChemDiv1_009676 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5cc(Cl)cc(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H19 compound treatment 281.5 95.7 0.5 285.5 95.0 0.49 0.702 1.0 1852863 ChemDiv1_009677 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(F)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H20 compound treatment 275.0 89.2 0.47 288.0 97.5 0.51 0.6872 0.9991 1272595 ChemDiv1_009678 COc1ccc(cc1Br)C(=O)Nc2cc(ccc2Cl)c3nc4cc(C)ccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H21 compound treatment 277.9 92.1 0.48 284.5 94.0 0.49 0.6851 1.0 1852874 ChemDiv1_009679 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OCC)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H22 compound treatment 274.8 89.0 0.46 289.7 99.2 0.52 0.6927 0.9986 1974651 ChemDiv1_009680 Brc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2Cc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H23 mock treatment 279.5 93.7 0.49 282.2 91.7 0.48 0.6825 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 H24 mock treatment 81.2 -105.0 -0.55 84.0 -107.0 -0.55 -0.7775 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I01 compound treatment 282.2 96.4 0.5 292.7 102.0 0.53 0.7311 0.9996 1197614 ChemDiv1_009681 Cc1ccn2cc(nc2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I02 compound treatment 282.4 96.6 0.5 293.5 103.0 0.54 0.7347 0.9995 1864040 ChemDiv1_009682 [O-][N+](=O)c1ccc(cc1)c2nc(Nc3cccc(c3)[N+](=O)[O-])c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I03 compound treatment 285.9 100.0 0.52 298.0 107.0 0.56 0.7642 0.9994 1974652 ChemDiv1_009683 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(Br)c3)c4ccccc24)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I04 compound treatment 278.5 92.7 0.48 295.4 105.0 0.55 0.7273 0.9982 1864052 ChemDiv1_009684 [O-][N+](=O)c1ccc(cc1)c2nc(NCC3CCCO3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I05 compound treatment 275.1 89.3 0.47 295.6 105.0 0.55 0.7155 0.9968 1974653 ChemDiv1_009685 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(c3)C(F)(F)F)c4ccccc24)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I06 compound treatment 278.3 92.5 0.48 295.9 105.0 0.55 0.7284 0.998 1864067 ChemDiv1_009686 [O-][N+](=O)c1ccc(cc1)c2nc(N3CCCCCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I07 compound treatment 283.3 97.5 0.51 298.4 108.0 0.56 0.7561 0.9988 1974654 ChemDiv1_009687 COc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CCC(=O)O)C3=O)/c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I08 compound treatment 280.7 94.9 0.49 298.5 108.0 0.56 0.7468 0.998 1864076 ChemDiv1_009688 CN(C1CCN(C)CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I09 compound treatment 279.5 93.7 0.49 298.0 107.0 0.56 0.7406 0.9978 1974655 ChemDiv1_009689 OC(=O)CCCN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I10 compound treatment 275.2 89.4 0.47 295.8 105.0 0.55 0.7166 0.9968 1395277 ChemDiv1_009690 Cc1ccc(cc1)S(=O)(=O)n2c(SCc3ccccc3)nc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I11 compound treatment 277.2 91.4 0.48 291.4 101.0 0.52 0.7078 0.9989 1225162 ChemDiv1_009691 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3ccc(C)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I12 compound treatment 347.7 162.0 0.84 357.0 166.0 0.87 1.209 0.9999 1974656 ChemDiv1_009692 CCc1nnc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4cccs4)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I13 compound treatment 276.2 90.4 0.47 293.3 103.0 0.53 0.7111 0.998 1540085 ChemDiv1_009693 COc1ccc(cc1F)c2cn3cccc(C)c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I14 compound treatment 277.1 91.3 0.48 292.8 102.0 0.53 0.7126 0.9985 1974657 ChemDiv1_009694 CCc1ccc(cc1)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCC(=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I15 compound treatment 279.5 93.7 0.49 293.4 103.0 0.53 0.7237 0.999 1742353 ChemDiv1_009695 COC(=O)C1=C(C)NC(=C(C1c2ccc(OC(=O)c3oc4ccccc4c3C)c(OC)c2)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I16 compound treatment 280.5 94.7 0.49 293.8 103.0 0.54 0.7288 0.9991 1974658 ChemDiv1_009696 OCC1(OC2C=C1)C3C2C(=O)N(C3=O)c4ccc(Cl)c(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I17 compound treatment 279.8 94.0 0.49 288.0 97.5 0.51 0.7049 0.9999 1924936 ChemDiv1_009697 COCCOC(=O)c1c(C)oc2ccc(OC(=O)c3ccc(OC)c(OC)c3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I18 compound treatment 273.8 88.0 0.46 273.8 83.3 0.43 0.6306 0.9996 1605991 ChemDiv1_009698 CCOC(=O)C1=C(C)N=c2sc(=Cc3c(OC)cc(OC)cc3OC)c(=O)n2C1c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I19 compound treatment 277.2 91.4 0.48 291.6 101.0 0.53 0.7086 0.9988 1974659 ChemDiv1_009699 CCOC(=O)c1ccc(cc1)N2N=C(C)/C(=C\c3ccc(OCc4ccccc4)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I20 compound treatment 278.3 92.5 0.48 286.6 96.1 0.5 0.6943 0.9998 1974660 ChemDiv1_009700 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)c2nc3ccccc3s2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I21 compound treatment 276.9 91.1 0.48 284.1 93.6 0.49 0.6799 0.9999 1974661 ChemDiv1_009701 Cc1cccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I22 compound treatment 273.9 88.1 0.46 284.1 93.6 0.49 0.6688 0.9996 1974662 ChemDiv1_009702 Cc1cc(C)c(C#N)c(SCC(O)CS(=O)(=O)Cc2ccc(Cl)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I23 mock treatment 277.2 91.4 0.48 283.4 92.9 0.48 0.6784 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 I24 mock treatment 74.4 -111.0 -0.58 81.0 -110.0 -0.57 -0.8136 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J01 compound treatment 280.1 94.3 0.49 291.7 101.0 0.53 0.7196 0.9994 1974663 ChemDiv1_009703 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccc(C)cc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J02 compound treatment 280.3 94.5 0.49 293.1 103.0 0.53 0.7255 0.9992 1852882 ChemDiv1_009704 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(c3)[N+](=O)[O-])C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J03 compound treatment 281.7 95.9 0.5 288.5 98.0 0.51 0.7138 1.0 1974664 ChemDiv1_009705 CN(C)c1nc(OCCOC(=O)COc2ccc(Cl)cc2Cl)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J04 compound treatment 284.0 98.2 0.51 296.7 106.0 0.55 0.7524 0.9993 1427700 ChemDiv1_009706 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc4OCOc4c3)C1=O)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J05 compound treatment 279.1 93.3 0.49 293.2 103.0 0.53 0.7215 0.9989 1374090 ChemDiv1_009707 COc1ccc(OC)c(c1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J06 compound treatment 279.9 94.1 0.49 294.0 103.0 0.54 0.7274 0.9989 1852907 ChemDiv1_009708 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(C)sc3C)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J07 compound treatment 281.8 96.0 0.5 296.2 106.0 0.55 0.7424 0.9989 1974665 ChemDiv1_009709 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(cc2)c3nc4cc(C)cc(C)c4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J08 compound treatment 278.8 93.0 0.48 295.1 105.0 0.54 0.7273 0.9984 1974666 ChemDiv1_009710 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccccc3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J09 compound treatment 277.1 91.3 0.48 295.6 105.0 0.55 0.7229 0.9977 1852823 ChemDiv1_009711 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3Cl)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J10 compound treatment 278.4 92.6 0.48 292.9 102.0 0.53 0.7178 0.9988 1974667 ChemDiv1_009712 CCOc1ccc(NC(=O)CSc2nc3sc(CC)cc3c(=O)n2CC=C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J11 compound treatment 277.4 91.6 0.48 291.7 101.0 0.53 0.7097 0.9988 1213599 ChemDiv1_009713 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3OC)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J12 compound treatment 276.6 90.8 0.47 294.1 104.0 0.54 0.7155 0.9979 1201460 ChemDiv1_009714 CN1CCN(CC1)c2nc(NCc3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J13 compound treatment 276.3 90.5 0.47 295.0 104.0 0.54 0.7178 0.9975 1513934 ChemDiv1_009715 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)c(OC)c3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J14 compound treatment 280.4 94.6 0.49 295.2 105.0 0.54 0.7336 0.9988 1143902 ChemDiv1_009716 Clc1cccc(Nc2nc(NCc3ccco3)c4ccccc4n2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J15 compound treatment 277.9 92.1 0.48 291.9 101.0 0.53 0.7123 0.9989 1852846 ChemDiv1_009717 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(C)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J16 compound treatment 273.1 87.3 0.46 292.8 102.0 0.53 0.6979 0.997 1616178 ChemDiv1_009718 COc1ccccc1Nc2nc(N3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J17 compound treatment 278.9 93.1 0.49 290.7 100.0 0.52 0.7115 0.9994 1852853 ChemDiv1_009719 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)[N+](=O)[O-])C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J18 compound treatment 275.6 89.8 0.47 291.4 101.0 0.52 0.7019 0.9984 1974668 ChemDiv1_009720 CCOC(=O)c1ccc(cc1)N2N=C(C)/C(=C\c3ccc(o3)c4ccc(Cl)c(c4)C(=O)O)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J19 compound treatment 282.3 96.5 0.5 290.6 100.0 0.52 0.7237 0.9999 1623863 ChemDiv1_009721 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(F)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J20 compound treatment 274.4 88.6 0.46 283.8 93.3 0.48 0.6696 0.9997 1273951 ChemDiv1_009722 CCOc1ccc(cc1Br)C(=O)Nc2cc(ccc2Cl)c3nc4cc(C)ccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J21 compound treatment 280.0 94.2 0.49 285.2 94.7 0.49 0.6954 1.0 1852875 ChemDiv1_009723 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OCC)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J22 compound treatment 277.2 91.4 0.48 282.0 91.5 0.48 0.6733 1.0 1974669 ChemDiv1_009724 Brc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2Cc4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J23 mock treatment 277.6 91.8 0.48 283.5 93.0 0.48 0.6803 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 J24 mock treatment 77.2 -109.0 -0.57 84.7 -106.0 -0.55 -0.7896 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K01 compound treatment 284.5 98.7 0.51 293.0 102.0 0.53 0.7406 0.9999 1272298 ChemDiv1_009725 Cc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K02 compound treatment 283.0 97.2 0.51 291.0 100.0 0.52 0.7278 0.9999 1864042 ChemDiv1_009726 OC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K03 compound treatment 285.4 99.6 0.52 294.8 104.0 0.54 0.7506 0.9998 1974670 ChemDiv1_009727 Clc1ccccc1c2c(OC(=O)CCN3C(=O)/C(=C/c4cccs4)/SC3=S)ccc5oc(=O)sc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K04 compound treatment 280.0 94.2 0.49 294.2 104.0 0.54 0.7285 0.9989 1864053 ChemDiv1_009728 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K05 compound treatment 279.8 94.0 0.49 293.2 103.0 0.53 0.724 0.9991 1974671 ChemDiv1_009729 OC(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(c3)C(F)(F)F)c4ccccc24)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K06 compound treatment 276.8 91.0 0.47 297.2 107.0 0.55 0.7277 0.997 1864068 ChemDiv1_009730 CC1CCCCN1c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K07 compound treatment 279.5 93.7 0.49 298.1 108.0 0.56 0.7409 0.9977 1974672 ChemDiv1_009731 Brc1ccc2N(CC=C)C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K08 compound treatment 279.8 94.0 0.49 293.9 103.0 0.54 0.7266 0.9989 1326814 ChemDiv1_009732 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K09 compound treatment 290.9 105.0 0.55 301.2 111.0 0.58 0.7944 0.9997 1974673 ChemDiv1_009733 OC(=O)CN1C(=O)/C(=C/2\SC(=S)N(CCS(=O)(=O)O)C2=O)/c3cc(Br)ccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K10 compound treatment 279.4 93.6 0.49 293.4 103.0 0.53 0.7233 0.999 1974674 ChemDiv1_009734 Cc1ccsc1/C=C\2/NC(=O)NC2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K11 compound treatment 278.6 92.8 0.48 294.6 104.0 0.54 0.7248 0.9984 1558761 ChemDiv1_009735 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3cc(C)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K12 compound treatment 286.5 101.0 0.53 301.7 111.0 0.58 0.78 0.9989 1974675 ChemDiv1_009736 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K13 compound treatment 276.8 91.0 0.47 292.2 102.0 0.53 0.7093 0.9985 1719671 ChemDiv1_009737 COc1ccc(cc1F)c2cn3ccc(C)cc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K14 compound treatment 279.6 93.8 0.49 294.6 104.0 0.54 0.7285 0.9987 1974676 ChemDiv1_009738 Cc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K15 compound treatment 275.9 90.1 0.47 288.1 97.6 0.51 0.6909 0.9993 1418704 ChemDiv1_009739 CCOC(=O)c1c(C)n(c2ccc(cc2)N(CC)CC)c3ccc(OCC#C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K16 compound treatment 277.8 92.0 0.48 286.9 96.4 0.5 0.6935 0.9998 1974677 ChemDiv1_009740 CCOC(=O)c1cc(ccc1Cl)N2C(=O)C3C4OC(C=C4)(C(OC(=O)C)OC(=O)C)C3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K17 compound treatment 276.8 91.0 0.47 291.1 101.0 0.52 0.7053 0.9988 1230440 ChemDiv1_009741 CCOC(=O)c1c(oc2ccc(OCC(=O)OCc3ccccc3)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K18 compound treatment 311.4 126.0 0.66 313.9 123.0 0.64 0.9167 0.9999 1640900 ChemDiv1_009742 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)cc3OC)c(=O)n2C1c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K19 compound treatment 278.8 93.0 0.48 289.7 99.2 0.52 0.7075 0.9995 1974678 ChemDiv1_009743 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)C(=O)O)C)cc(Br)c1OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K20 compound treatment 280.3 94.5 0.49 286.3 95.8 0.5 0.7005 1.0 1145353 ChemDiv1_009744 O=S(=O)(CCSc1nc2CCCCc2cc1C#N)Cc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K21 compound treatment 274.6 88.8 0.46 285.6 95.1 0.49 0.6769 0.9995 1864030 ChemDiv1_009745 Oc1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K22 compound treatment 278.1 92.3 0.48 279.4 88.9 0.46 0.6671 0.9998 1360308 ChemDiv1_009746 OC(COc1ccc(Cl)cc1)CSc2nc3CCCCc3cc2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K23 mock treatment 279.7 93.9 0.49 283.1 92.6 0.48 0.6866 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 K24 mock treatment 76.8 -109.0 -0.57 79.3 -111.0 -0.58 -0.811 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L01 compound treatment 279.9 94.1 0.49 292.6 102.0 0.53 0.7222 0.9992 1304147 ChemDiv1_009747 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)Nc3ccc(C)cc3C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L02 compound treatment 286.0 100.0 0.52 286.5 96.0 0.5 0.7223 0.9997 1852883 ChemDiv1_009748 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(c3)[N+](=O)[O-])C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L03 compound treatment 280.2 94.4 0.49 289.8 99.3 0.52 0.713 0.9997 1400232 ChemDiv1_009749 CCCCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L04 compound treatment 281.2 95.4 0.5 292.5 102.0 0.53 0.7266 0.9995 1370204 ChemDiv1_009750 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L05 compound treatment 277.8 92.0 0.48 290.4 99.9 0.52 0.7064 0.9992 1536631 ChemDiv1_009751 COc1ccc(C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nc5ccccc5s4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L06 compound treatment 283.2 97.4 0.51 293.0 102.0 0.53 0.7359 0.9997 1852936 ChemDiv1_009752 CN(C)N1C(=C(C#N)C(C2=C1CC(CC2=O)c3ccccc3)c4ccc(Br)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L07 compound treatment 278.0 92.2 0.48 292.6 102.0 0.53 0.7152 0.9988 1701183 ChemDiv1_009753 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3C)c4nc5ncccc5o4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L08 compound treatment 279.7 93.9 0.49 296.9 106.0 0.55 0.7373 0.9982 1974679 ChemDiv1_009754 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(F)cc3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L09 compound treatment 279.5 93.7 0.49 293.9 103.0 0.54 0.7255 0.9989 1852824 ChemDiv1_009755 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3Cl)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L10 compound treatment 280.4 94.6 0.49 291.6 101.0 0.53 0.7204 0.9995 1974680 ChemDiv1_009756 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(OC)cc3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L11 compound treatment 280.4 94.6 0.49 292.6 102.0 0.53 0.7241 0.9993 1852834 ChemDiv1_009757 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(CC)CC)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L12 compound treatment 275.2 89.4 0.47 289.3 98.8 0.51 0.6927 0.9988 1591665 ChemDiv1_009758 OCCN1CCN(CC1)c2nc(NCc3ccccc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L13 compound treatment 281.4 95.6 0.5 291.9 101.0 0.53 0.7252 0.9996 1852840 ChemDiv1_009759 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)c(OC)c3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L14 compound treatment 276.6 90.8 0.47 293.8 103.0 0.54 0.7144 0.998 1441651 ChemDiv1_009760 Fc1ccccc1Nc2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L15 compound treatment 277.6 91.8 0.48 270.7 80.2 0.42 0.6332 0.9976 1852847 ChemDiv1_009761 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(C)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L16 compound treatment 280.8 95.0 0.5 293.6 103.0 0.54 0.7292 0.9992 1168079 ChemDiv1_009762 C1CN(CCO1)c2nc(nc3ccccc23)N4CCN(CC4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L17 compound treatment 276.2 90.4 0.47 286.7 96.2 0.5 0.6869 0.9996 1852854 ChemDiv1_009763 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)[N+](=O)[O-])C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L18 compound treatment 278.1 92.3 0.48 288.1 97.6 0.51 0.699 0.9997 1927246 ChemDiv1_009764 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)ccc1OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L19 compound treatment 277.9 92.1 0.48 292.2 102.0 0.53 0.7134 0.9989 1852870 ChemDiv1_009765 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(Br)c3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L20 compound treatment 278.2 92.4 0.48 286.3 95.8 0.5 0.6928 0.9999 1149777 ChemDiv1_009766 Nc1ncnc2n(CCOc3ccccc3)c(S)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L21 compound treatment 278.6 92.8 0.48 278.6 88.1 0.46 0.666 0.9996 1349783 ChemDiv1_009767 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OCC)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L22 compound treatment 272.4 86.6 0.45 283.5 93.0 0.48 0.6611 0.9994 1974681 ChemDiv1_009768 Brc1ccc(cc1)C(=O)CSc2nnc(c3cccnc3)n2Cc4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L23 mock treatment 275.9 90.1 0.47 280.7 90.2 0.47 0.6637 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 L24 mock treatment 79.0 -107.0 -0.56 87.1 -103.0 -0.54 -0.7742 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M01 compound treatment 280.5 94.7 0.49 290.3 99.8 0.52 0.716 0.9997 1321163 ChemDiv1_009769 Clc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M02 compound treatment 284.1 98.3 0.51 289.7 99.2 0.52 0.727 1.0 1864043 ChemDiv1_009770 OC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M03 compound treatment 278.4 92.6 0.48 290.0 99.5 0.52 0.7071 0.9994 1974682 ChemDiv1_009771 COc1ccc(cc1)c2c(OC(=O)CCN3C(=O)/C(=C/c4cccs4)/SC3=S)ccc5oc(=O)sc25 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M04 compound treatment 281.3 95.5 0.5 292.6 102.0 0.53 0.7274 0.9995 1864055 ChemDiv1_009772 CN(C)CCNc1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M05 compound treatment 280.1 94.3 0.49 289.6 99.1 0.52 0.7119 0.9997 1974683 ChemDiv1_009773 Fc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M06 compound treatment 277.3 91.5 0.48 287.2 96.7 0.5 0.6928 0.9997 1864069 ChemDiv1_009774 CC1CCCN(C1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M07 compound treatment 280.3 94.5 0.49 295.7 105.0 0.55 0.7351 0.9987 1974684 ChemDiv1_009775 Brc1ccc2N(CC=C)C(=O)/C(=C/3\SC(=S)N(Cc4ccco4)C3=O)/c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M08 compound treatment 274.1 88.3 0.46 293.2 103.0 0.53 0.703 0.9973 1307732 ChemDiv1_009776 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3cc4c(ccc5ccccc54)oc3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M09 compound treatment 279.5 93.7 0.49 293.2 103.0 0.53 0.7229 0.999 1974685 ChemDiv1_009777 OC(=O)CN1C(=O)/C(=C/2\SC(=NC2=O)N3CCOCC3)/c4cc(Br)ccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M10 compound treatment 275.6 89.8 0.47 293.6 103.0 0.54 0.71 0.9977 1974686 ChemDiv1_009778 Fc1ccc(NC(=O)COc2ccccc2/C=C\3/NC(=O)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M11 compound treatment 277.8 92.0 0.48 293.0 102.0 0.53 0.7159 0.9986 1123814 ChemDiv1_009779 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3cc(Cl)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M12 compound treatment 279.2 93.4 0.49 288.6 98.1 0.51 0.7049 0.9997 1151148 ChemDiv1_009780 Nc1c(sc2nc3CCCc3cc12)C(=O)Nc4nccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M13 compound treatment 278.1 92.3 0.48 290.2 99.7 0.52 0.7067 0.9993 1191953 ChemDiv1_009781 COc1ccc(cc1F)c2cn3cc(C)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M14 compound treatment 273.1 87.3 0.46 290.5 100.0 0.52 0.6894 0.9978 1974687 ChemDiv1_009782 COc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M15 compound treatment 276.6 90.8 0.47 289.8 99.3 0.52 0.6997 0.9991 1974688 ChemDiv1_009783 CC(C)(C)C(=O)Nc1nc(cs1)C2CCCN2S(=O)(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M16 compound treatment 279.9 94.1 0.49 287.4 96.9 0.5 0.7031 0.9999 1709254 ChemDiv1_009784 Cc1ccc(cc1NC(=O)c2ccc(C#N)cc2F)c3nc4ncccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M17 compound treatment 275.7 89.9 0.47 287.9 97.4 0.51 0.6894 0.9993 1974689 ChemDiv1_009785 CCOC(=O)c1c(oc2ccc(OCc3c(F)cccc3Cl)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M18 compound treatment 277.3 91.5 0.48 287.2 96.7 0.5 0.6928 0.9997 1974690 ChemDiv1_009786 COCc1cc(C)nc(SCc2ccc(Cl)cc2Cl)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M19 compound treatment 276.1 90.3 0.47 288.6 98.1 0.51 0.6935 0.9992 1974691 ChemDiv1_009787 COc1ccc(cc1)C2C(=C(N)Oc3c2c(C)nn3c4ccc(Br)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M20 compound treatment 277.8 92.0 0.48 280.3 89.8 0.47 0.6693 0.9999 1572702 ChemDiv1_009788 CCS(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M21 compound treatment 279.8 94.0 0.49 282.8 92.3 0.48 0.6858 0.9999 1864031 ChemDiv1_009789 Oc1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M22 compound treatment 278.7 92.9 0.48 281.9 91.4 0.48 0.6785 1.0 1243790 ChemDiv1_009790 OC(CSc1nc2CCCCc2cc1C#N)CS(=O)(=O)Cc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M23 mock treatment 278.9 93.1 0.49 282.6 92.1 0.48 0.6818 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 M24 mock treatment 194.5 8.66 0.05 190.6 0.0906 0.0 0.0323 0.7144 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N01 compound treatment 284.2 98.4 0.51 292.6 102.0 0.53 0.7381 0.9999 1701246 ChemDiv1_009791 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)c(OC)c3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N02 compound treatment 282.6 96.8 0.5 290.1 99.6 0.52 0.723 0.9999 1852884 ChemDiv1_009792 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(c3)[N+](=O)[O-])C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N03 compound treatment 284.5 98.7 0.51 290.0 99.5 0.52 0.7296 1.0 1680628 ChemDiv1_009793 COc1cc(C)nc(NC(=O)Nc2sc(NS(=O)(=O)c3ccc(C)cc3)nc2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N04 compound treatment 283.4 97.6 0.51 290.4 99.9 0.52 0.727 0.9999 1852888 ChemDiv1_009794 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N05 compound treatment 280.6 94.8 0.49 291.5 101.0 0.52 0.7207 0.9995 1522078 ChemDiv1_009795 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nc5ccccc5s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N06 compound treatment 278.7 92.9 0.48 287.3 96.8 0.5 0.6983 0.9998 1974692 ChemDiv1_009796 CN(C)N1C(=C(C#N)C(C2=C1CC(CC2=O)c3ccccc3)c4ccccc4C(F)(F)F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N07 compound treatment 279.6 93.8 0.49 286.9 96.4 0.5 0.7002 0.9999 1852819 ChemDiv1_009797 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)ccc3OC)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N08 compound treatment 276.4 90.6 0.47 290.5 100.0 0.52 0.7016 0.9989 1974693 ChemDiv1_009798 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(Cl)cc3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N09 compound treatment 273.6 87.8 0.46 291.1 101.0 0.52 0.6935 0.9978 1296304 ChemDiv1_009799 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3Cl)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N10 compound treatment 276.1 90.3 0.47 291.8 101.0 0.53 0.7053 0.9984 1307201 ChemDiv1_009800 CCc1cc2c(=O)n(CC=C)c(SCc3nc4ccccc4[nH]3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N11 compound treatment 283.2 97.4 0.51 294.1 104.0 0.54 0.7399 0.9996 1852835 ChemDiv1_009801 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(CC)CC)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N12 compound treatment 278.0 92.2 0.48 291.9 101.0 0.53 0.7126 0.9989 1701346 ChemDiv1_009802 Cc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N13 compound treatment 278.3 92.5 0.48 288.6 98.1 0.51 0.7016 0.9996 1852841 ChemDiv1_009803 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Cl)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N14 compound treatment 271.4 85.6 0.45 285.9 95.4 0.5 0.6662 0.9986 1143772 ChemDiv1_009804 COc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N15 compound treatment 277.9 92.1 0.48 289.5 99.0 0.51 0.7034 0.9994 1852848 ChemDiv1_009805 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(C)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N16 compound treatment 281.6 95.8 0.5 291.2 101.0 0.52 0.7233 0.9997 1974694 ChemDiv1_009806 CCc1cc2c(SCC(=O)Nc3ccc(Br)cc3)ncnc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N17 compound treatment 272.6 86.8 0.45 289.1 98.6 0.51 0.6824 0.9981 1852855 ChemDiv1_009807 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)[N+](=O)[O-])C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N18 compound treatment 281.0 95.2 0.5 284.1 93.6 0.49 0.695 0.9999 1974695 ChemDiv1_009808 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5ccc(cc5)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N19 compound treatment 274.3 88.5 0.46 288.2 97.7 0.51 0.6854 0.9989 1157815 ChemDiv1_009809 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(Br)c3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N20 compound treatment 279.2 93.4 0.49 283.7 93.2 0.48 0.6869 1.0 1615295 ChemDiv1_009810 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)Cn3cnc4ccccc4c3=O)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N21 compound treatment 278.2 92.4 0.48 282.4 91.9 0.48 0.6784 1.0 1852876 ChemDiv1_009811 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(SC)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N22 compound treatment 280.1 94.3 0.49 283.7 93.2 0.48 0.6902 1.0 1974696 ChemDiv1_009812 COc1cc(cc(Br)c1OCc2ccccc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N23 mock treatment 279.6 93.8 0.49 282.1 91.6 0.48 0.6825 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 N24 mock treatment 188.0 2.16 0.01 188.8 -1.71 -0.01 0.0017 0.1179 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O01 compound treatment 287.5 102.0 0.53 290.3 99.8 0.52 0.7418 0.9999 1974697 ChemDiv1_009813 Clc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O02 compound treatment 282.3 96.5 0.5 284.8 94.3 0.49 0.7024 0.9999 1974698 ChemDiv1_009814 COCCCNc1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O03 compound treatment 282.6 96.8 0.5 286.4 95.9 0.5 0.7094 1.0 1974699 ChemDiv1_009815 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O04 compound treatment 279.7 93.9 0.49 284.6 94.1 0.49 0.6921 1.0 1864056 ChemDiv1_009816 [O-][N+](=O)c1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O05 compound treatment 277.6 91.8 0.48 286.6 96.1 0.5 0.6917 0.9998 1974700 ChemDiv1_009817 Fc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O06 compound treatment 280.2 94.4 0.49 289.8 99.3 0.52 0.713 0.9997 1864070 ChemDiv1_009818 CC1CCN(CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O07 compound treatment 288.7 103.0 0.54 305.1 115.0 0.6 0.8006 0.9986 1974701 ChemDiv1_009819 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC=C)c3ccc(Br)cc23)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O08 compound treatment 280.1 94.3 0.49 287.1 96.6 0.5 0.7027 0.9999 1473453 ChemDiv1_009820 COC(=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O09 compound treatment 274.2 88.4 0.46 288.4 97.9 0.51 0.6857 0.9988 1974702 ChemDiv1_009821 Cc1ccc(CN2C(=O)/C(=C/3\SC(=S)N(CCS(=O)(=O)O)C3=O)/c4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O10 compound treatment 278.6 92.8 0.48 288.7 98.2 0.51 0.7031 0.9996 1974703 ChemDiv1_009822 COc1ccc(cc1)n2cccc2/C=C\3/NC(=O)NC3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O11 compound treatment 279.1 93.3 0.49 290.5 100.0 0.52 0.7115 0.9995 1411395 ChemDiv1_009823 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(OC)c3)c4ccccc4)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O12 compound treatment 275.9 90.1 0.47 292.2 102.0 0.53 0.706 0.9983 1393388 ChemDiv1_009824 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc5CCCc5cc4c3N)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O13 compound treatment 280.7 94.9 0.49 290.6 100.0 0.52 0.7178 0.9997 1736615 ChemDiv1_009825 COc1ccc(cc1F)c2cn3cc(Cl)ccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O14 compound treatment 277.2 91.4 0.48 291.8 101.0 0.53 0.7093 0.9988 1974704 ChemDiv1_009826 COc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O15 compound treatment 275.1 89.3 0.47 291.1 101.0 0.52 0.699 0.9983 1481834 ChemDiv1_009827 Nc1c(oc2ccccc12)C(=O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O16 compound treatment 278.9 93.1 0.49 286.3 95.8 0.5 0.6954 0.9999 1401846 ChemDiv1_009828 Fc1cc(C#N)ccc1C(=O)Nc2cc(ccc2Cl)c3nc4ncccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O17 compound treatment 279.5 93.7 0.49 289.5 99.0 0.51 0.7093 0.9997 1974705 ChemDiv1_009829 CCOC(=O)c1c(oc2ccc(OCc3ccc(Br)cc3)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O18 compound treatment 282.0 96.2 0.5 287.7 97.2 0.51 0.7119 1.0 1974706 ChemDiv1_009830 COCc1c(C#N)c(Nc2cccc(c2)C(F)(F)F)nc(C)c1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O19 compound treatment 277.1 91.3 0.48 282.1 91.6 0.48 0.6733 1.0 1974707 ChemDiv1_009831 Fc1ccc(cc1)C(=O)CSc2ncn[nH]2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O20 compound treatment 262.9 77.1 0.4 275.3 84.8 0.44 0.5959 0.9989 1467951 ChemDiv1_009832 COc1ccc(cc1)c2cc(c(C#N)c(n2)S(=O)C)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O21 compound treatment 278.8 93.0 0.48 283.6 93.1 0.48 0.6851 1.0 1864032 ChemDiv1_009833 COc1ccccc1Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O22 compound treatment 278.3 92.5 0.48 280.3 89.8 0.47 0.6711 0.9999 1173840 ChemDiv1_009834 OC(CSc1nc2CCCCc2cc1C#N)CS(=O)(=O)Cc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O23 mock treatment 279.1 93.3 0.49 281.2 90.7 0.47 0.6774 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 O24 mock treatment 96.7 -89.1 -0.46 93.2 -97.3 -0.51 -0.6865 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P01 compound treatment 284.5 98.7 0.51 286.1 95.6 0.5 0.7153 0.9998 1249918 ChemDiv1_009835 COc1ccc(OC)c(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Cl)cc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P02 compound treatment 284.0 98.2 0.51 286.8 96.3 0.5 0.716 0.9999 1852885 ChemDiv1_009836 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Br)cc3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P03 compound treatment 280.3 94.5 0.49 283.0 92.5 0.48 0.6884 0.9999 1684540 ChemDiv1_009837 CCOC(=O)c1ccc(Oc2nc(OC)nc(n2)N(C)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P04 compound treatment 285.8 100.0 0.52 289.5 99.0 0.51 0.7326 1.0 1852889 ChemDiv1_009838 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P05 compound treatment 283.0 97.2 0.51 288.4 97.9 0.51 0.7182 1.0 1974708 ChemDiv1_009839 NC(=O)C1NCCc2c1[nH]c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P06 compound treatment 281.7 95.9 0.5 291.5 101.0 0.52 0.7248 0.9997 1461315 ChemDiv1_009840 COc1cc(ccc1OCc2ccccc2)C3C(=C(N)N(N(C)C)C4=C3C(=O)CCC4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P07 compound treatment 281.2 95.4 0.5 290.2 99.7 0.52 0.7182 0.9998 1377057 ChemDiv1_009841 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)ccc3OC)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P08 compound treatment 278.6 92.8 0.48 291.3 101.0 0.52 0.7126 0.9992 1974709 ChemDiv1_009842 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(C)cc3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P09 compound treatment 282.9 97.1 0.51 289.6 99.1 0.52 0.7222 1.0 1852825 ChemDiv1_009843 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3OC)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P10 compound treatment 279.2 93.4 0.49 287.9 97.4 0.51 0.7024 0.9998 1974710 ChemDiv1_009844 CCc1cc2c(=O)n(CC=C)c(SCC(=O)c3cccs3)nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P11 compound treatment 281.1 95.3 0.5 293.8 103.0 0.54 0.731 0.9993 1852836 ChemDiv1_009845 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(CC)CC)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P12 compound treatment 280.3 94.5 0.49 289.5 99.0 0.51 0.7123 0.9998 1647041 ChemDiv1_009846 Cc1ccccc1Nc2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P13 compound treatment 280.9 95.1 0.5 289.5 99.0 0.51 0.7145 0.9998 1852842 ChemDiv1_009847 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Cl)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P14 compound treatment 277.6 91.8 0.48 288.9 98.4 0.51 0.7001 0.9995 1313914 ChemDiv1_009848 CCOc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P15 compound treatment 281.0 95.2 0.5 287.7 97.2 0.51 0.7083 1.0 1852849 ChemDiv1_009849 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3C)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P16 compound treatment 279.0 93.2 0.49 290.1 99.6 0.52 0.7097 0.9995 1974711 ChemDiv1_009850 Cc1sc2ncnc(SCC(=O)c3ccc(Br)cc3)c2c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P17 compound treatment 275.8 90.0 0.47 287.2 96.7 0.5 0.6872 0.9994 1852856 ChemDiv1_009851 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(O)c(OC)c3)C1=O)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P18 compound treatment 276.3 90.5 0.47 289.8 99.3 0.52 0.6986 0.999 1974712 ChemDiv1_009852 COc1cc(/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccc(cc3)S(=O)(=O)N)ccc1OCc4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P19 compound treatment 277.9 92.1 0.48 285.5 95.0 0.49 0.6887 0.9999 1852871 ChemDiv1_009853 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(Br)c3)C1=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P20 compound treatment 276.9 91.1 0.48 285.6 95.1 0.49 0.6854 0.9998 1974713 ChemDiv1_009854 Fc1ccccc1/C=C\2/SC(=O)N(CCNC3=NS(=O)(=O)c4ccccc34)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P21 compound treatment 280.8 95.0 0.5 282.4 91.9 0.48 0.688 0.9998 1852877 ChemDiv1_009855 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(SC)cc3)C1=O)c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P22 compound treatment 280.8 95.0 0.5 283.8 93.3 0.48 0.6932 0.9999 1974714 ChemDiv1_009856 COc1cccc(C2C(=C(N)Oc3[nH]nc(C)c23)C#N)c1OCc4c(F)cccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P23 mock treatment 281.0 95.2 0.5 284.8 94.3 0.49 0.6976 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.614 P24 mock treatment 68.2 -118.0 -0.61 94.9 -95.6 -0.5 -0.7853 -0.9945 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A01 compound treatment 285.6 100.0 0.52 293.6 104.0 0.54 0.7512 0.9999 1540529 ChemDiv1_009857 COc1ccc(cc1OCc2ccc(cc2)C(=O)OCC(C)C)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A02 compound treatment 283.3 97.9 0.51 292.3 103.0 0.53 0.738 0.9998 1974715 ChemDiv1_009858 CCCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A03 compound treatment 279.9 94.5 0.49 289.3 99.5 0.52 0.7144 0.9997 1308677 ChemDiv1_009859 COC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A04 compound treatment 287.8 102.0 0.53 292.7 103.0 0.53 0.7561 1.0 1124923 ChemDiv1_009860 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A05 compound treatment 278.8 93.4 0.49 292.6 103.0 0.53 0.7225 0.9989 1974716 ChemDiv1_009861 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Br)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A06 compound treatment 279.2 93.8 0.49 290.9 101.0 0.53 0.7177 0.9994 1370242 ChemDiv1_009862 CCOc1ccc(cc1)S(=O)(=O)Nc2cc3c(C(=O)OC)c(oc3c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A07 compound treatment 285.1 99.7 0.52 294.2 104.0 0.54 0.7516 0.9998 1724541 ChemDiv1_009863 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)c(Cl)c3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A08 compound treatment 276.4 91.0 0.47 286.2 96.4 0.5 0.6901 0.9996 1449876 ChemDiv1_009864 COCc1oc2c(cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24)c1C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A09 compound treatment 373.7 188.0 0.98 372.7 183.0 0.95 1.367 0.9999 1974717 ChemDiv1_009865 O=C/1N(CC2CCCO2)C(=S)S\C1=C/c3c(NCCCn4ccnc4)nc5ccccn5c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A10 compound treatment 275.9 90.5 0.47 294.0 104.0 0.54 0.7169 0.9977 1286371 ChemDiv1_009866 COc1cccc(OC)c1OCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A11 compound treatment 389.9 205.0 1.07 392.5 203.0 1.05 1.4995 1.0 1974718 ChemDiv1_009867 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c(NCCc4ccccc4)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A12 compound treatment 277.5 92.1 0.48 288.0 98.2 0.51 0.7008 0.9995 1974719 ChemDiv1_009868 CC(C)CN1C(=O)/C(=C/c2cn(nc2c3ccc(cc3)S(=O)(=O)N(C)C)c4ccccc4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A13 compound treatment 370.3 185.0 0.96 386.1 196.0 1.02 1.4037 0.9996 1974720 ChemDiv1_009869 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCCCC(=O)O)C3=O)c(nc12)N4CCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A14 compound treatment 272.7 87.3 0.46 290.1 100.0 0.52 0.6908 0.9977 1974721 ChemDiv1_009870 CCOc1ccc(cc1)c2nn(cc2C3C(=C(C)NC(=C3C(=O)OCCOC)C)C(=O)OCCOC)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A15 compound treatment 280.3 94.9 0.5 288.0 98.2 0.51 0.7111 0.9999 1462514 ChemDiv1_009871 CCCn1nc(Oc2nc(nc(n2)N(C)C)N(C)C)ccc1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A16 compound treatment 278.4 93.0 0.49 285.6 95.8 0.5 0.6953 0.9999 1974722 ChemDiv1_009872 CCCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccc(C)cc3)C2=O)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A17 compound treatment 279.0 93.6 0.49 285.2 95.4 0.5 0.696 1.0 1480335 ChemDiv1_009873 OC1(CC(=O)c2ccc3CCc4cccc2c43)C(=O)N(CC#C)c5ccccc51 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A18 compound treatment 276.9 91.5 0.48 281.7 91.9 0.48 0.6754 1.0 1742793 ChemDiv1_009874 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)S(=O)(=O)N4CCOCC4)c5ccccc5)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A19 compound treatment 277.9 92.5 0.48 285.8 96.0 0.5 0.6942 0.9999 1974723 ChemDiv1_009875 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A20 compound treatment 279.8 94.4 0.49 287.7 97.9 0.51 0.7082 0.9999 1974724 ChemDiv1_009876 COc1nc(cc(c1C#N)c2ccc(F)cc2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A21 compound treatment 277.1 91.7 0.48 279.7 89.9 0.47 0.6688 0.9999 1277738 ChemDiv1_009877 CCCc1oc2ccc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc2c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A22 compound treatment 272.4 87.0 0.45 281.4 91.6 0.48 0.6577 0.9997 1157713 ChemDiv1_009878 Cc1cccn2c(NC(=O)c3ccc(Br)cc3)c(nc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A23 mock treatment 279.9 94.5 0.49 280.0 90.2 0.47 0.6802 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 A24 mock treatment 83.0 -102.0 -0.53 83.4 -106.0 -0.55 -0.7687 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B01 compound treatment 283.0 97.6 0.51 291.3 102.0 0.53 0.7332 0.9998 1925170 ChemDiv1_009879 CCOc1ccc(cc1[N+](=O)[O-])c2nn(cc2C3C(=C(C)NC(=C3C(=O)OC)C)C(=O)OC)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B02 compound treatment 282.5 97.1 0.51 293.5 104.0 0.54 0.7394 0.9995 1974725 ChemDiv1_009880 [O-][N+](=O)c1cc(ccc1Cl)C(=O)COC(=O)c2ccccc2N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B03 compound treatment 279.9 94.5 0.49 288.9 99.1 0.52 0.7129 0.9998 1974726 ChemDiv1_009881 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OCC)c(c3)[N+](=O)[O-])c4ccccc4)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B04 compound treatment 277.2 91.8 0.48 286.5 96.7 0.5 0.6942 0.9997 1445050 ChemDiv1_009882 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B05 compound treatment 278.1 92.7 0.48 288.4 98.6 0.51 0.7045 0.9996 1277385 ChemDiv1_009883 CCCCC(=O)N1C(C)CC(Nc2ccccc2C)c3cccc(C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B06 compound treatment 277.5 92.1 0.48 291.1 101.0 0.53 0.7122 0.999 1974727 ChemDiv1_009884 Cn1cnnc1SCC(=O)Nc2ccc(Br)c3cccnc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B07 compound treatment 276.2 90.8 0.47 287.7 97.9 0.51 0.6949 0.9994 1134216 ChemDiv1_009885 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc4ccccc4s3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B08 compound treatment 276.9 91.5 0.48 288.7 98.9 0.51 0.7011 0.9993 1974728 ChemDiv1_009886 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B09 compound treatment 274.7 89.3 0.47 291.7 102.0 0.53 0.7041 0.998 1974729 ChemDiv1_009887 Cc1ccc2nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccc(Cl)c(Cl)c4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B10 compound treatment 280.9 95.5 0.5 292.4 103.0 0.53 0.7295 0.9994 1313139 ChemDiv1_009888 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5cc(OC)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B11 compound treatment 276.3 90.9 0.47 283.7 93.9 0.49 0.6806 0.9999 1974730 ChemDiv1_009889 NC(=O)CSc1nc(cc(c2cccs2)c1C#N)c3ccc4ccccc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B12 compound treatment 276.6 91.2 0.48 289.6 99.8 0.52 0.7033 0.9991 1574996 ChemDiv1_009890 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B13 compound treatment 274.0 88.6 0.46 291.8 102.0 0.53 0.7018 0.9977 1158240 ChemDiv1_009891 COc1ccc(cc1)c2cc(nc(SCC(=O)Nc3cc(C)on3)c2C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B14 compound treatment 275.0 89.6 0.47 284.2 94.4 0.49 0.6776 0.9997 1974731 ChemDiv1_009892 Clc1ccc(OCCNC(=O)CSc2nnc(s2)N3C(=O)c4ccccc4C3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B15 compound treatment 276.9 91.5 0.48 284.5 94.7 0.49 0.6857 0.9999 1659786 ChemDiv1_009893 CN1C2CCC1CC(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5cc(Cl)cc(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B16 compound treatment 276.5 91.1 0.48 288.0 98.2 0.51 0.6971 0.9994 1160049 ChemDiv1_009894 O=C(CN1C(=O)c2ccccc2S1(=O)=O)N3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B17 compound treatment 276.1 90.7 0.47 290.0 100.0 0.52 0.703 0.9989 1974732 ChemDiv1_009895 [O-][N+](=O)c1cccc(c1)C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B18 compound treatment 294.2 109.0 0.57 295.6 106.0 0.55 0.7903 0.9999 1927412 ChemDiv1_009896 Brc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)N4CCOCC4)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B19 compound treatment 273.6 88.2 0.46 283.6 93.8 0.49 0.6702 0.9996 1435088 ChemDiv1_009897 CC1C=CCC2C1C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B20 compound treatment 278.1 92.7 0.48 281.3 91.5 0.48 0.6784 1.0 1974733 ChemDiv1_009898 CCCCOC(=O)c1ccc(cc1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B21 compound treatment 276.3 90.9 0.47 283.7 93.9 0.49 0.6806 0.9999 1786524 ChemDiv1_009899 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B22 compound treatment 277.3 91.9 0.48 283.5 93.7 0.49 0.6835 1.0 1882550 ChemDiv1_009900 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B23 mock treatment 278.3 92.9 0.48 280.3 90.5 0.47 0.6754 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 B24 mock treatment 71.8 -114.0 -0.59 78.4 -111.0 -0.58 -0.8284 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C01 compound treatment 280.0 94.6 0.49 296.7 107.0 0.56 0.742 0.9983 1131715 ChemDiv1_009901 CC(=O)Oc1ccccc1c2nc3sc(=C4C(=O)N(CC(=O)N)c5ccccc45)c(=O)n3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C02 compound treatment 285.2 99.8 0.52 293.8 104.0 0.54 0.7505 0.9998 1974734 ChemDiv1_009902 CCCCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C03 compound treatment 279.4 94.0 0.49 292.6 103.0 0.53 0.7247 0.9991 1974735 ChemDiv1_009903 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3cccs3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C04 compound treatment 280.7 95.3 0.5 292.8 103.0 0.54 0.7302 0.9993 1237810 ChemDiv1_009904 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C05 compound treatment 332.3 147.0 0.77 340.7 151.0 0.78 1.0966 0.9999 1974736 ChemDiv1_009905 COCCCN1C(=O)/C(=C/c2c(NCCc3ccccc3)nc4ccccn4c2=O)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C06 compound treatment 278.1 92.7 0.48 289.7 99.9 0.52 0.7092 0.9994 1227226 ChemDiv1_009906 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C07 compound treatment 278.1 92.7 0.48 287.8 98.0 0.51 0.7023 0.9997 1974737 ChemDiv1_009907 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3cccs3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C08 compound treatment 278.8 93.4 0.49 295.3 106.0 0.55 0.7324 0.9983 1123475 ChemDiv1_009908 Cc1oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc2c1C(=O)OCc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C09 compound treatment 304.8 119.0 0.62 318.6 129.0 0.67 0.914 0.9994 1974738 ChemDiv1_009909 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(Cc4ccco4)C3=O)c(NCc5ccccc5)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C10 compound treatment 274.3 88.9 0.46 291.9 102.0 0.53 0.7033 0.9978 1974739 ChemDiv1_009910 COC(=O)c1ccc(OCCOCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C11 compound treatment 428.6 243.0 1.27 433.0 243.0 1.26 1.7911 1.0 1974740 ChemDiv1_009911 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c(nc12)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C12 compound treatment 278.4 93.0 0.49 286.3 96.5 0.5 0.6979 0.9999 1974741 ChemDiv1_009912 CCCCN1C(=O)/C(=C/c2cn(nc2c3ccc(cc3)S(=O)(=O)N4CCOCC4)c5ccccc5)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C13 compound treatment 300.9 116.0 0.6 309.2 119.0 0.62 0.865 0.9999 1974742 ChemDiv1_009913 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCCCC(=O)O)C3=O)c(NCCN4CCOCC4)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C14 compound treatment 278.1 92.7 0.48 287.2 97.4 0.51 0.7001 0.9997 1974743 ChemDiv1_009914 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccc(Cl)cc3)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C15 compound treatment 277.3 91.9 0.48 289.9 100.0 0.52 0.707 0.9992 1622245 ChemDiv1_009915 CN(C)c1nc(Oc2ccc(OCC(=O)N)nn2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C16 compound treatment 276.0 90.6 0.47 284.5 94.7 0.49 0.6824 0.9998 1974744 ChemDiv1_009916 CCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccc(C)cc3)C2=O)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C17 compound treatment 274.9 89.5 0.47 284.6 94.8 0.49 0.6787 0.9996 1133757 ChemDiv1_009917 CC(C(=O)c1ccccc1)C2(O)C(=O)N(CC#C)c3ccccc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C18 compound treatment 280.8 95.4 0.5 286.9 97.1 0.5 0.7089 1.0 1925141 ChemDiv1_009918 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(Cl)c3Cl)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C19 compound treatment 278.0 92.6 0.48 285.9 96.1 0.5 0.6949 0.9999 1257743 ChemDiv1_009919 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(Br)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C20 compound treatment 275.4 90.0 0.47 282.0 92.2 0.48 0.671 0.9999 1185229 ChemDiv1_009920 COC(=O)c1sc(=S)n(CC=C)c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C21 compound treatment 278.3 92.9 0.48 284.8 95.0 0.49 0.692 1.0 1442214 ChemDiv1_009921 CCCc1oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc2c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C22 compound treatment 274.8 89.4 0.47 279.9 90.1 0.47 0.6611 1.0 1474080 ChemDiv1_009922 Cc1ccc2nc(c(NC(=O)c3ccco3)n2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C23 mock treatment 274.9 89.5 0.47 282.5 92.7 0.48 0.671 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 C24 mock treatment 77.2 -108.0 -0.56 75.7 -114.0 -0.59 -0.8184 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D01 compound treatment 283.3 97.9 0.51 295.0 105.0 0.55 0.7479 0.9994 1226085 ChemDiv1_009923 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(Br)c3)c4ccccc4)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D02 compound treatment 282.5 97.1 0.51 290.4 101.0 0.52 0.728 0.9999 1974745 ChemDiv1_009924 [O-][N+](=O)c1cc(ccc1Cl)C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D03 compound treatment 275.3 89.9 0.47 294.5 105.0 0.54 0.7166 0.9973 1225503 ChemDiv1_009925 COC(=O)Nc1c(nc2ccc(Cl)cn12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D04 compound treatment 275.5 90.1 0.47 291.4 102.0 0.53 0.7059 0.9983 1680475 ChemDiv1_009926 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D05 compound treatment 282.3 96.9 0.51 289.0 99.2 0.52 0.7222 1.0 1974746 ChemDiv1_009927 COc1cccc(c1)C(=O)N2C(C)CC(N(C(=O)CN3C(=O)c4ccccc4C3=O)c5ccccc5)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D06 compound treatment 282.1 96.7 0.5 306.2 116.0 0.61 0.7846 0.9959 1974747 ChemDiv1_009928 COc1cc(ccc1OCc2c(F)cccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D07 compound treatment 275.4 90.0 0.47 290.0 100.0 0.52 0.7004 0.9987 1585565 ChemDiv1_009929 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4ccc(OC)c(OC)c4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D08 compound treatment 280.6 95.2 0.5 291.3 102.0 0.53 0.7243 0.9995 1974748 ChemDiv1_009930 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D09 compound treatment 275.4 90.0 0.47 291.6 102.0 0.53 0.7063 0.9982 1579917 ChemDiv1_009931 NC(=O)C1CCN(CC1)c2nc(Nc3ccccc3)nc(Nc4ccccc4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D10 compound treatment 280.7 95.3 0.5 296.3 107.0 0.55 0.7431 0.9986 1686102 ChemDiv1_009932 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(C)c4ccccc34)c(=O)n2C1c5cc(OC)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D11 compound treatment 267.0 81.6 0.43 276.7 86.9 0.45 0.6205 0.9996 1974749 ChemDiv1_009933 CC(=O)C1=C(C)OC(=C(C#N)C1c2cccs2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D12 compound treatment 293.2 108.0 0.56 302.2 112.0 0.58 0.8109 0.9998 1465178 ChemDiv1_009934 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(C)c4ccccc34)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D13 compound treatment 275.9 90.5 0.47 293.3 104.0 0.54 0.7144 0.9979 1458654 ChemDiv1_009935 Cc1cc(NC(=O)CSc2nc3CCCc3c(c2C#N)c4cccnc4)no1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D14 compound treatment 275.8 90.4 0.47 290.9 101.0 0.53 0.7052 0.9985 1974750 ChemDiv1_009936 [O-][N+](=O)c1cccc(COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D15 compound treatment 276.8 91.4 0.48 289.7 99.9 0.52 0.7045 0.9991 1974751 ChemDiv1_009937 COc1cc(/C=C\2/NC(=S)NC2=O)ccc1OC(=O)C3(CC4CC5CC(C4)C3)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D16 compound treatment 268.8 83.4 0.44 288.7 98.9 0.51 0.6713 0.9966 1974752 ChemDiv1_009938 CCN1C(=O)/C(=C/c2ccc(o2)c3cccc(Cl)c3C)/N(CC)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D17 compound treatment 277.8 92.4 0.48 290.4 101.0 0.52 0.7107 0.9992 1974753 ChemDiv1_009939 CC(C)C(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)OCC(=O)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D18 compound treatment 277.1 91.7 0.48 284.6 94.8 0.49 0.6868 0.9999 1948457 ChemDiv1_009940 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cc(C)cc(C)c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D19 compound treatment 274.2 88.8 0.46 285.8 96.0 0.5 0.6805 0.9993 1974754 ChemDiv1_009941 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D20 compound treatment 276.7 91.3 0.48 283.2 93.4 0.49 0.6802 1.0 1974755 ChemDiv1_009942 Clc1ccc(cc1)C2SCC(=O)N2Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D21 compound treatment 271.9 86.5 0.45 284.5 94.7 0.49 0.6673 0.9991 1226279 ChemDiv1_009943 Cc1ccc(cc1C)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D22 compound treatment 277.1 91.7 0.48 281.7 91.9 0.48 0.6762 1.0 1974756 ChemDiv1_009944 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D23 mock treatment 278.8 93.4 0.49 285.0 95.2 0.49 0.6946 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 D24 mock treatment 76.9 -108.0 -0.57 81.5 -108.0 -0.56 -0.7982 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E01 compound treatment 276.2 90.8 0.47 288.1 98.3 0.51 0.6964 0.9993 1586734 ChemDiv1_009945 CC(=O)Oc1ccccc1c2nc3sc(=C4C(=O)N(CC=C)c5ccccc45)c(=O)n3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E02 compound treatment 281.6 96.2 0.5 290.4 101.0 0.52 0.7247 0.9998 1974757 ChemDiv1_009946 CCCCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(OC)cc3)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E03 compound treatment 279.4 94.0 0.49 293.1 103.0 0.54 0.7265 0.999 1974758 ChemDiv1_009947 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E04 compound treatment 279.0 93.6 0.49 290.5 101.0 0.52 0.7155 0.9994 1332996 ChemDiv1_009948 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E05 compound treatment 372.2 187.0 0.97 370.4 181.0 0.94 1.353 0.9998 1974759 ChemDiv1_009949 O=C/1N(Cc2ccco2)C(=S)S\C1=C/c3c(NCCCn4ccnc4)nc5ccccn5c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E06 compound treatment 278.9 93.5 0.49 290.7 101.0 0.52 0.7159 0.9993 1319511 ChemDiv1_009950 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E07 compound treatment 280.4 95.0 0.5 295.8 106.0 0.55 0.7402 0.9986 1974760 ChemDiv1_009951 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3cccs3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E08 compound treatment 280.4 95.0 0.5 289.2 99.4 0.52 0.7159 0.9998 1612085 ChemDiv1_009952 CC(C)(C)C1CCc2c(C1)sc3[nH]c(=S)n(C4CCCCC4)c(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E09 compound treatment 356.0 171.0 0.89 361.5 172.0 0.89 1.2605 1.0 1974761 ChemDiv1_009953 COCCN1C(=O)/C(=C/c2c(NCCN3CCOCC3)nc4c(C)cccn4c2=O)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E10 compound treatment 279.0 93.6 0.49 291.5 102.0 0.53 0.7192 0.9992 1974762 ChemDiv1_009954 COc1ccc(OCCOCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E11 compound treatment 276.4 91.0 0.47 293.7 104.0 0.54 0.7177 0.9979 1974763 ChemDiv1_009955 CC1=C(C(NC(=O)N1)c2cn(nc2c3cccs3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E12 compound treatment 275.0 89.6 0.47 290.8 101.0 0.53 0.7019 0.9983 1642697 ChemDiv1_009956 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)cc3)c4ccccc4)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E13 compound treatment 274.4 89.0 0.46 299.7 110.0 0.57 0.7324 0.9947 1164137 ChemDiv1_009957 CCOc1ccc(cc1C)c2nn(cc2C3NC(=O)NC(=C3C(=O)OC)C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E14 compound treatment 263.2 77.8 0.41 274.2 84.4 0.44 0.5973 0.9993 1974764 ChemDiv1_009958 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccccc3[N+](=O)[O-])C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E15 compound treatment 275.3 89.9 0.47 288.4 98.6 0.51 0.6941 0.999 1974765 ChemDiv1_009959 Cn1c(=O)n(C)c2cc(/C=C\3/NC(=O)N(Cc4ccc(Br)cc4)C3=O)ccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E16 compound treatment 396.7 211.0 1.1 397.4 208.0 1.08 1.5426 0.9999 1974766 ChemDiv1_009960 CCN(CC)c1ccc(/C=C/2\SC(=S)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E17 compound treatment 277.1 91.7 0.48 291.2 101.0 0.53 0.7111 0.9988 1974767 ChemDiv1_009961 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(CC#C)c3ccccc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E18 compound treatment 279.3 93.9 0.49 291.5 102.0 0.53 0.7203 0.9993 1925111 ChemDiv1_009962 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(Br)c3)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E19 compound treatment 275.8 90.4 0.47 287.4 97.6 0.51 0.6923 0.9993 1640385 ChemDiv1_009963 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E20 compound treatment 276.3 90.9 0.47 286.9 97.1 0.5 0.6923 0.9995 1316457 ChemDiv1_009964 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)scc1c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E21 compound treatment 276.2 90.8 0.47 278.5 88.7 0.46 0.6611 0.9999 1167327 ChemDiv1_009965 CCCc1oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc2c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E22 compound treatment 276.1 90.7 0.47 280.4 90.6 0.47 0.6677 1.0 1215383 ChemDiv1_009966 Clc1ccc2nc(c(NC(=O)c3ccco3)n2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E23 mock treatment 279.6 94.2 0.49 281.8 92.0 0.48 0.6857 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 E24 mock treatment 75.8 -110.0 -0.57 83.8 -106.0 -0.55 -0.7938 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F01 compound treatment 280.4 95.0 0.5 294.1 104.0 0.54 0.7339 0.999 1974768 ChemDiv1_009967 COc1ccc(cc1[N+](=O)[O-])c2nn(cc2C3C(=C(C)NC(=C3C(=O)OCC=C)C)C(=O)OCC=C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F02 compound treatment 283.0 97.6 0.51 290.1 100.0 0.52 0.7288 0.9999 1851903 ChemDiv1_009968 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F03 compound treatment 280.5 95.1 0.5 293.4 104.0 0.54 0.7317 0.9992 1300294 ChemDiv1_009969 Cc1ccc(cc1)c2nc3ccc(C)cn3c2NC(=O)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F04 compound treatment 281.0 95.6 0.5 293.7 104.0 0.54 0.7346 0.9992 1974769 ChemDiv1_009970 O=C(COC(=O)c1ccc(cc1)N2C(=O)C3C(C4C=CC3C5CC54)C2=O)c6cccs6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F05 compound treatment 280.5 95.1 0.5 292.7 103.0 0.53 0.7291 0.9993 1401761 ChemDiv1_009971 Cn1cnnc1SCC(=O)n2c3CCCCc3c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F06 compound treatment 279.4 94.0 0.49 299.1 109.0 0.57 0.7486 0.9973 1974770 ChemDiv1_009972 Cc1n[nH]c2OC(=C(C#N)C(c12)c3cc(ccc3OCc4ccc(Br)cc4)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F07 compound treatment 279.8 94.4 0.49 294.3 105.0 0.54 0.7324 0.9988 1487696 ChemDiv1_009973 COc1ccc(Nc2nc(Cl)nc(Nc3ccc(OC)c(OC)c3)n2)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F08 compound treatment 289.8 104.0 0.54 296.7 107.0 0.56 0.7781 1.0 1974771 ChemDiv1_009974 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F09 compound treatment 273.9 88.5 0.46 293.8 104.0 0.54 0.7088 0.9969 1974772 ChemDiv1_009975 COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(Sc4nncn4C)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F10 compound treatment 280.6 95.2 0.5 292.6 103.0 0.53 0.7291 0.9993 1229944 ChemDiv1_009976 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5ccc(OC)c(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F11 compound treatment 279.3 93.9 0.49 292.8 103.0 0.54 0.7251 0.999 1358551 ChemDiv1_009977 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F12 compound treatment 353.7 168.0 0.88 363.8 174.0 0.9 1.2605 0.9999 1727916 ChemDiv1_009978 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4ccc(Br)o4)c(=O)n23)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F13 compound treatment 272.4 87.0 0.45 292.6 103.0 0.53 0.6989 0.9967 1974773 ChemDiv1_009979 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2C3CCN(CC3)C(=O)OCc4ccccc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F14 compound treatment 274.1 88.7 0.46 291.0 101.0 0.53 0.6993 0.998 1974774 ChemDiv1_009980 [O-][N+](=O)c1ccc(COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Br)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F15 compound treatment 272.7 87.3 0.46 292.0 102.0 0.53 0.6978 0.9971 1262382 ChemDiv1_009981 OC(=O)c1cccc(Nc2nc(nc(n2)N3CCCC3)N4CCCC4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F16 compound treatment 276.5 91.1 0.48 289.5 99.7 0.52 0.7026 0.9991 1974775 ChemDiv1_009982 COc1cccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F17 compound treatment 275.6 90.2 0.47 289.6 99.8 0.52 0.6997 0.9988 1974776 ChemDiv1_009983 CC(C)C(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)OCC(=O)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F18 compound treatment 280.7 95.3 0.5 288.7 98.9 0.51 0.7152 0.9999 1974777 ChemDiv1_009984 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Cl)cc(OC)c3O)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F19 compound treatment 275.1 89.7 0.47 284.7 94.9 0.49 0.6798 0.9997 1178688 ChemDiv1_009985 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F20 compound treatment 276.1 90.7 0.47 286.9 97.1 0.5 0.6916 0.9995 1974778 ChemDiv1_009986 CC1SC(N(Nc2nc(nc(n2)N3CCOCC3)N4CCOCC4)C1=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F21 compound treatment 273.6 88.2 0.46 281.1 91.3 0.47 0.661 0.9999 1623412 ChemDiv1_009987 CC(OC(=O)c1cccc(c1)N2C(=O)C3CC=CC(C)C3C2=O)C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F22 compound treatment 409.5 224.0 1.17 411.0 221.0 1.15 1.6398 1.0 1974779 ChemDiv1_009988 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3O)[N+](=O)[O-])c(=O)n2C1c4ccc(SC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F23 mock treatment 276.7 91.3 0.48 282.3 92.5 0.48 0.6769 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 F24 mock treatment 82.3 -103.0 -0.54 81.1 -109.0 -0.57 -0.7797 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G01 compound treatment 282.2 96.8 0.51 295.8 106.0 0.55 0.7468 0.9991 1303084 ChemDiv1_009989 CCN1C(=O)C(=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G02 compound treatment 283.2 97.8 0.51 294.2 104.0 0.54 0.7446 0.9995 1974780 ChemDiv1_009990 CCCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G03 compound treatment 281.5 96.1 0.5 297.1 107.0 0.56 0.749 0.9986 1974781 ChemDiv1_009991 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G04 compound treatment 287.5 102.0 0.53 299.7 110.0 0.57 0.7807 0.9994 1323559 ChemDiv1_009992 COC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G05 compound treatment 324.8 139.0 0.73 329.0 139.0 0.72 1.026 1.0 1974782 ChemDiv1_009993 COc1ccc(CCN2C(=O)/C(=C/c3c(nc4ccccn4c3=O)N5CCCCC5)/SC2=S)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G06 compound treatment 278.7 93.3 0.49 293.9 104.0 0.54 0.7269 0.9986 1182095 ChemDiv1_009994 COCc1oc2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2c1C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G07 compound treatment 296.5 111.0 0.58 300.7 111.0 0.58 0.8175 1.0 1974783 ChemDiv1_009995 COc1ccc(CCN2C(=O)/C(=C/c3c(NCc4ccccc4)nc5ccccn5c3=O)/SC2=S)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G08 compound treatment 278.3 92.9 0.48 296.3 107.0 0.55 0.7342 0.9978 1477911 ChemDiv1_009996 Cn1c(=O)c2c3CCCc3sc2n4c(SCC(=O)c5ccc(Br)cc5)nnc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G09 compound treatment 337.9 153.0 0.8 343.7 154.0 0.8 1.1283 1.0 1974784 ChemDiv1_009997 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)c(NCc5ccco5)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G10 compound treatment 275.8 90.4 0.47 293.7 104.0 0.54 0.7155 0.9977 1974785 ChemDiv1_009998 O=C(CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G11 compound treatment 279.6 94.2 0.49 294.9 105.0 0.55 0.7339 0.9986 1739114 ChemDiv1_009999 CCOc1ccc(cc1)c2nn(cc2C3NC(=O)NC(=C3C(=O)OCC=C)C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G12 compound treatment 277.7 92.3 0.48 292.0 102.0 0.53 0.7162 0.9988 1974786 ChemDiv1_010000 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3cccc(c3)[N+](=O)[O-])c4ccccc4)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G13 compound treatment 277.9 92.5 0.48 293.9 104.0 0.54 0.7239 0.9984 1230133 ChemDiv1_010001 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(F)cc3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G14 compound treatment 279.1 93.7 0.49 289.6 99.8 0.52 0.7126 0.9996 1974787 ChemDiv1_010002 Cc1c(N2C(=O)/C(=C/c3ccc(Br)cc3)/SC2=S)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G15 compound treatment 283.2 97.8 0.51 291.5 102.0 0.53 0.7347 0.9998 1974788 ChemDiv1_010003 COc1cc(/C=C\2/NC(=O)N(Cc3ccc(Br)cc3)C2=O)cc4OCOc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G16 compound treatment 309.8 124.0 0.65 320.5 131.0 0.68 0.9394 0.9997 1974789 ChemDiv1_010004 Clc1ccc(cc1)c2ccc(/C=C\3/NC(=S)N(C3=O)c4ccccc4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G17 compound treatment 275.1 89.7 0.47 289.9 100.0 0.52 0.6989 0.9986 1974790 ChemDiv1_010005 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(C)c3ccccc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G18 compound treatment 274.3 88.9 0.46 289.3 99.5 0.52 0.6938 0.9985 1925168 ChemDiv1_010006 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(Cl)c3)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G19 compound treatment 275.2 89.8 0.47 282.5 92.7 0.48 0.6721 0.9999 1927833 ChemDiv1_010007 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G20 compound treatment 273.7 88.3 0.46 287.7 97.9 0.51 0.6857 0.9988 1924938 ChemDiv1_010008 Cc1ccn2c(NC(=O)/C=C/c3ccccc3)c(nc2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G21 compound treatment 275.6 90.2 0.47 282.8 93.0 0.48 0.6747 0.9999 1567944 ChemDiv1_010009 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24)c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G22 compound treatment 278.4 93.0 0.49 286.0 96.2 0.5 0.6968 0.9999 1218183 ChemDiv1_010010 Clc1ccc2nc(c(NC(=O)c3cccs3)n2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G23 mock treatment 279.9 94.5 0.49 283.0 93.2 0.48 0.6913 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 G24 mock treatment 67.2 -118.0 -0.62 80.2 -110.0 -0.57 -0.8387 -0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H01 compound treatment 279.5 94.1 0.49 292.3 103.0 0.53 0.724 0.9992 1974791 ChemDiv1_010011 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3cccs3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H02 compound treatment 286.4 101.0 0.53 292.4 103.0 0.53 0.7498 1.0 1974792 ChemDiv1_010012 CC1CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H03 compound treatment 282.1 96.7 0.5 288.3 98.5 0.51 0.7189 1.0 1585322 ChemDiv1_010013 CC(C)OC(=O)C1=C(C)N(C)C(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H04 compound treatment 278.3 92.9 0.48 288.6 98.8 0.51 0.7059 0.9996 1481161 ChemDiv1_010014 CC(C(=O)c1ccc(C)cc1)c2nc3ccccc3[nH]c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H05 compound treatment 279.8 94.4 0.49 291.4 102.0 0.53 0.7218 0.9994 1288485 ChemDiv1_010015 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)NC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H06 compound treatment 280.8 95.4 0.5 293.7 104.0 0.54 0.7339 0.9992 1974793 ChemDiv1_010016 COc1ccc(C2C(=C(N)Oc3[nH]nc(C)c23)C#N)c(OCc4ccccc4Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H07 compound treatment 277.3 91.9 0.48 289.7 99.9 0.52 0.7063 0.9992 1974794 ChemDiv1_010017 CC1=CC(C)(C)N(C(=O)CSc2nncn2C)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H08 compound treatment 276.5 91.1 0.48 293.7 104.0 0.54 0.718 0.998 1974795 ChemDiv1_010018 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1Oc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H09 compound treatment 273.5 88.1 0.46 292.9 103.0 0.54 0.704 0.9971 1156629 ChemDiv1_010019 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H10 compound treatment 307.3 122.0 0.64 323.5 134.0 0.69 0.9412 0.999 1142146 ChemDiv1_010020 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5ccc(OC)c(OCC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H11 compound treatment 276.5 91.1 0.48 295.0 105.0 0.55 0.7228 0.9976 1974796 ChemDiv1_010021 CSc1nc(N)nc(SCCS(=O)(=O)c2ccc(C)cc2)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H12 compound treatment 273.4 88.0 0.46 275.4 85.6 0.44 0.6393 0.9999 1583216 ChemDiv1_010022 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cn(C)c5ccccc45)c(=O)n23)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H13 compound treatment 294.9 110.0 0.57 311.4 122.0 0.63 0.851 0.9987 1216641 ChemDiv1_010023 COc1ccc(cc1)C(=O)c2sc3nc(ccc3c2N)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H14 compound treatment 278.6 93.2 0.49 293.1 103.0 0.54 0.7236 0.9988 1974797 ChemDiv1_010024 CCN1C(=O)C(=Cc2ccc(o2)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)N(CC)C1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H15 compound treatment 277.9 92.5 0.48 291.3 102.0 0.53 0.7144 0.999 1581583 ChemDiv1_010025 OC(=O)c1ccccc1Nc2nc(nc(n2)N3CCCC3)N4CCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H16 compound treatment 283.9 98.5 0.51 300.0 110.0 0.57 0.7685 0.9985 1974798 ChemDiv1_010026 CCOc1cccc(c1)N2C(=O)/C(=C\c3cc(Br)c(O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H17 compound treatment 273.8 88.4 0.46 290.9 101.0 0.53 0.6978 0.9979 1974799 ChemDiv1_010027 Brc1ccc(cc1)C(=O)COC(=O)C(CCCCN2C(=O)C3C4CC(C=C4)C3C2=O)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H18 compound treatment 166.9 -18.5 -0.1 177.2 -12.6 -0.07 -0.1144 -0.9823 1974800 ChemDiv1_010028 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(CC=C)c(O)c(OC)c3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H19 compound treatment 282.7 97.3 0.51 278.9 89.1 0.46 0.6865 0.9989 1974801 ChemDiv1_010029 CC(=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccc(C)cc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H20 compound treatment 278.3 92.9 0.48 282.9 93.1 0.48 0.685 1.0 1456964 ChemDiv1_010030 O=C1CSC(N1Nc2nc(nc(n2)N3CCCCC3)N4CCCCC4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H21 compound treatment 277.6 92.2 0.48 281.1 91.3 0.47 0.6758 1.0 1851890 ChemDiv1_010031 Cc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccccc2N3C(=O)C4CC=CCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H22 compound treatment 275.5 90.1 0.47 285.4 95.6 0.5 0.6839 0.9996 1974802 ChemDiv1_010032 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5cccc(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H23 mock treatment 282.5 97.1 0.51 283.0 93.2 0.48 0.7008 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 H24 mock treatment 81.5 -104.0 -0.54 84.6 -105.0 -0.55 -0.7698 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I01 compound treatment 280.0 94.6 0.49 288.1 98.3 0.51 0.7104 0.9999 1579586 ChemDiv1_010033 CCCN1C(=O)C(=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I02 compound treatment 282.5 97.1 0.51 295.5 106.0 0.55 0.7468 0.9992 1371161 ChemDiv1_010034 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I03 compound treatment 287.0 102.0 0.53 292.6 103.0 0.53 0.7527 1.0 1974803 ChemDiv1_010035 CC1=C(C(NC(=O)N1)c2cn(nc2c3cccs3)c4ccccc4)C(=O)OCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I04 compound treatment 280.2 94.8 0.49 293.2 103.0 0.54 0.7299 0.9991 1347857 ChemDiv1_010036 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3cc(C)ccc3C)c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I05 compound treatment 344.7 159.0 0.83 352.0 162.0 0.84 1.1839 1.0 1974804 ChemDiv1_010037 O=C/1N(Cc2ccco2)C(=S)S\C1=C/c3c(NCc4ccco4)nc5ccccn5c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I06 compound treatment 279.1 93.7 0.49 293.9 104.0 0.54 0.7284 0.9987 1599336 ChemDiv1_010038 COCc1oc2c(cc(NS(=O)(=O)c3c(C)cc(C)cc3C)c4ccccc24)c1C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I07 compound treatment 306.3 121.0 0.63 317.2 127.0 0.66 0.9143 0.9997 1974805 ChemDiv1_010039 O=C/1N(CC2CCCO2)C(=S)S\C1=C/c3c(NCc4ccccc4)nc5ccccn5c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I08 compound treatment 278.2 92.8 0.48 293.5 104.0 0.54 0.7236 0.9986 1974806 ChemDiv1_010040 COC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc3ccccc3)NC(=O)OC(C)(C)C)C(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I09 compound treatment 292.3 107.0 0.56 301.1 111.0 0.58 0.8035 0.9998 1974807 ChemDiv1_010041 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CC4CCCO4)C3=O)c(NCc5ccccc5)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I10 compound treatment 275.1 89.7 0.47 295.2 105.0 0.55 0.7184 0.9969 1543179 ChemDiv1_010042 COC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I11 compound treatment 279.6 94.2 0.49 290.3 101.0 0.52 0.717 0.9995 1286147 ChemDiv1_010043 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(Cl)cc3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I12 compound treatment 279.8 94.4 0.49 291.4 102.0 0.53 0.7218 0.9994 1654349 ChemDiv1_010044 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(F)cc3)c4ccccc4)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I13 compound treatment 275.7 90.3 0.47 297.6 108.0 0.56 0.7294 0.9963 1283870 ChemDiv1_010045 O=C1CCCC2=C1C(C#Cc3ccccc3)C4=C(CCCC4=O)O2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I14 compound treatment 279.3 93.9 0.49 294.0 104.0 0.54 0.7295 0.9987 1974808 ChemDiv1_010046 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3cccc(c3)[N+](=O)[O-])c4ccccc4)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I15 compound treatment 275.5 90.1 0.47 290.0 100.0 0.52 0.7008 0.9987 1974809 ChemDiv1_010047 COc1cc(/C=C\2/NC(=O)NC2=O)cc(Cl)c1OCc3cccc(c3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I16 compound treatment 279.1 93.7 0.49 289.1 99.3 0.52 0.7107 0.9996 1974810 ChemDiv1_010048 CCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccccc3Cl)C2=O)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I17 compound treatment 280.9 95.5 0.5 294.2 104.0 0.54 0.7361 0.9991 1974811 ChemDiv1_010049 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I18 compound treatment 275.6 90.2 0.47 285.6 95.8 0.5 0.685 0.9996 1684052 ChemDiv1_010050 O=C1CSC(N1Cc2cccnc2)c3cn(nc3c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I19 compound treatment 280.0 94.6 0.49 292.4 103.0 0.53 0.7262 0.9993 1974812 ChemDiv1_010051 COCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3cc(Cl)ccc3Cl)c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I20 compound treatment 275.2 89.8 0.47 283.6 93.8 0.49 0.6761 0.9998 1974813 ChemDiv1_010052 O=C(Nc1c(nc2ccccn12)c3ccccc3)/C=C/c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I21 compound treatment 275.9 90.5 0.47 285.0 95.2 0.49 0.6839 0.9997 1295632 ChemDiv1_010053 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(OC)cc3)c4ccccc24)c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I22 compound treatment 278.8 93.4 0.49 283.5 93.7 0.49 0.689 1.0 1379042 ChemDiv1_010054 CCC(=O)Nc1c(nc2cc(C)ccn12)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I23 mock treatment 276.0 90.6 0.47 283.6 93.8 0.49 0.6791 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 I24 mock treatment 66.5 -119.0 -0.62 85.6 -104.0 -0.54 -0.8215 -0.9977 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J01 compound treatment 284.6 99.2 0.52 291.1 101.0 0.53 0.7384 1.0 1974814 ChemDiv1_010055 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3cccc(c3)[N+](=O)[O-])c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J02 compound treatment 281.9 96.5 0.5 288.7 98.9 0.51 0.7196 0.9999 1974815 ChemDiv1_010056 COc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4CC=CCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J03 compound treatment 279.2 93.8 0.49 291.0 101.0 0.53 0.7181 0.9994 1686757 ChemDiv1_010057 O=C(Nc1c(nc2ccccn12)c3ccccc3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J04 compound treatment 280.0 94.6 0.49 292.7 103.0 0.53 0.7273 0.9992 1974816 ChemDiv1_010058 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccc(Cl)c(Cl)c2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J05 compound treatment 278.2 92.8 0.48 289.9 100.0 0.52 0.7103 0.9994 1944355 ChemDiv1_010059 COc1ccc2N(C(=O)c3sc4cc(ccc4c3Cl)[N+](=O)[O-])C(C)(C)CC(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J06 compound treatment 280.9 95.5 0.5 294.5 105.0 0.54 0.7372 0.999 1974817 ChemDiv1_010060 Cc1n[nH]c2OC(=C(C#N)C(c12)c3cc(ccc3OCc4cccc(F)c4)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J07 compound treatment 283.2 97.8 0.51 298.8 109.0 0.57 0.7615 0.9986 1380461 ChemDiv1_010061 CC1=CC(C)(C)N(C(=O)CSc2nc3ccccc3[nH]2)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J08 compound treatment 280.5 95.1 0.5 294.8 105.0 0.55 0.7368 0.9989 1974818 ChemDiv1_010062 [O-][N+](=O)c1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J09 compound treatment 277.2 91.8 0.48 300.1 110.0 0.57 0.7442 0.996 1974819 ChemDiv1_010063 CN(C)c1ccc(/C=C\2/C(=NN(C2=O)c3nc(cs3)c4cccc(c4)[N+](=O)[O-])C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J10 compound treatment 274.7 89.3 0.47 291.7 102.0 0.53 0.7041 0.998 1182288 ChemDiv1_010064 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4cc(OC)c(OC)cc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J11 compound treatment 289.2 104.0 0.54 303.9 114.0 0.59 0.8024 0.999 1187818 ChemDiv1_010065 COc1ccc(cc1)C(=O)c2sc3nc(C)cc(c4cccs4)c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J12 compound treatment 293.5 108.0 0.56 309.3 120.0 0.62 0.8381 0.9988 1353044 ChemDiv1_010066 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4c[nH]c5ccccc45)c(=O)n23)C(=O)Nc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J13 compound treatment 279.4 94.0 0.49 292.6 103.0 0.53 0.7247 0.9991 1974820 ChemDiv1_010067 CCc1nc2sc(C(=O)Nc3cccc(c3)C(F)(F)F)c(N)c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J14 compound treatment 274.2 88.8 0.46 293.4 104.0 0.54 0.7085 0.9972 1974821 ChemDiv1_010068 OC(=O)c1ccc(Cl)c(c1)c2ccc(/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc5OCOc5c4)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J15 compound treatment 275.6 90.2 0.47 291.6 102.0 0.53 0.707 0.9983 1974822 ChemDiv1_010069 O=C1C2CCCCC2C(=O)N1CN3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J16 compound treatment 277.6 92.2 0.48 290.8 101.0 0.53 0.7114 0.9991 1946651 ChemDiv1_010070 COc1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J17 compound treatment 278.4 93.0 0.49 287.7 97.9 0.51 0.703 0.9997 1675595 ChemDiv1_010071 Clc1ccc(cc1)C(=O)COC(=O)c2cccc(c2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J18 compound treatment 316.3 131.0 0.68 329.7 140.0 0.73 0.9972 0.9995 1946335 ChemDiv1_010072 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(Br)o3)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J19 compound treatment 275.0 89.6 0.47 289.5 99.7 0.52 0.6971 0.9987 1525783 ChemDiv1_010073 Cc1ccc2nc(cc(C(=O)N3CCOCC3)c2c1)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J20 compound treatment 278.0 92.6 0.48 287.8 98.0 0.51 0.7019 0.9997 1974823 ChemDiv1_010074 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccn3c4cccc(c4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)c(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J21 compound treatment 274.9 89.5 0.47 284.8 95.0 0.49 0.6794 0.9996 1851892 ChemDiv1_010075 Cc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccccc2N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J22 compound treatment 279.7 94.3 0.49 284.1 94.3 0.49 0.6946 1.0 1974824 ChemDiv1_010076 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J23 mock treatment 279.2 93.8 0.49 283.9 94.1 0.49 0.692 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 J24 mock treatment 77.6 -108.0 -0.56 82.3 -108.0 -0.56 -0.7926 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K01 compound treatment 278.1 92.7 0.48 286.3 96.5 0.5 0.6967 0.9998 1232023 ChemDiv1_010077 CCCCN1C(=O)C(=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K02 compound treatment 280.8 95.4 0.5 294.6 105.0 0.54 0.7372 0.999 1286841 ChemDiv1_010078 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3c(C)cc(C)cc3C)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K03 compound treatment 275.5 90.1 0.47 288.6 98.8 0.51 0.6956 0.999 1974825 ChemDiv1_010079 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Br)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K04 compound treatment 284.6 99.2 0.52 291.6 102.0 0.53 0.7402 0.9999 1378602 ChemDiv1_010080 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(C)cc3C)c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K05 compound treatment 340.5 155.0 0.81 339.4 150.0 0.78 1.1221 0.9998 1974826 ChemDiv1_010081 COc1ccc(CCN2C(=O)/C(=C/c3c(NCCO)nc4ccccn4c3=O)/SC2=S)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K06 compound treatment 279.9 94.5 0.49 289.4 99.6 0.52 0.7148 0.9997 1429400 ChemDiv1_010082 CCc1ccc(cc1)S(=O)(=O)Nc2cc3c(C(=O)OC)c(COC)oc3c4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K07 compound treatment 359.5 174.0 0.91 367.8 178.0 0.93 1.2966 1.0 1974827 ChemDiv1_010083 COCCN1C(=O)/C(=C/c2c(NCCCn3ccnc3)nc4ccccn4c2=O)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K08 compound treatment 280.0 94.6 0.49 292.0 102.0 0.53 0.7247 0.9993 1974828 ChemDiv1_010084 CC(C)N1C(=O)C2(N3CC4(C)CN2CC(C)(C3)C4=O)c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K09 compound treatment 324.7 139.0 0.73 327.5 138.0 0.72 1.0201 1.0 1974829 ChemDiv1_010085 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)c(NCCN5CCOCC5)nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K10 compound treatment 282.9 97.5 0.51 288.2 98.4 0.51 0.7214 1.0 1940859 ChemDiv1_010086 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc4CCCCc4c3c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K11 compound treatment 282.0 96.6 0.5 292.5 103.0 0.53 0.7339 0.9996 1701250 ChemDiv1_010087 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(Br)cc3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K12 compound treatment 274.7 89.3 0.47 295.3 106.0 0.55 0.7173 0.9967 1312521 ChemDiv1_010088 CCOC(=O)C1=C(C)NC(=C(C1c2ccc(OC(=O)c3ccc(C)cc3)c(OC)c2)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K13 compound treatment 277.5 92.1 0.48 293.1 103.0 0.54 0.7195 0.9985 1311469 ChemDiv1_010089 CCNc1nc(NC(C)C)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K14 compound treatment 274.1 88.7 0.46 293.8 104.0 0.54 0.7096 0.997 1558025 ChemDiv1_010090 CCOc1ccc(cc1)c2nn(cc2C3C(=C(C)NC(=C3C(=O)OC)C)C(=O)OC)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K15 compound treatment 279.3 93.9 0.49 293.9 104.0 0.54 0.7291 0.9988 1974830 ChemDiv1_010091 Clc1ccc(Sc2oc(/C=C\3/NC(=O)NC3=O)cc2Br)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K16 compound treatment 274.2 88.8 0.46 289.8 100.0 0.52 0.6952 0.9984 1974831 ChemDiv1_010092 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3C(C=C(Cl)Cl)C3(C)C)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K17 compound treatment 273.1 87.7 0.46 291.0 101.0 0.53 0.6956 0.9976 1304552 ChemDiv1_010093 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2cc(O)ccc2O)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K18 compound treatment 284.9 99.5 0.52 293.7 104.0 0.54 0.749 0.9998 1974832 ChemDiv1_010094 COc1nc(cc(c1C#N)c2cccc(c2)[N+](=O)[O-])c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K19 compound treatment 276.0 90.6 0.47 288.5 98.7 0.51 0.6971 0.9992 1677350 ChemDiv1_010095 CCCc1oc2ccc(NS(=O)(=O)c3ccc(Br)cc3)cc2c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K20 compound treatment 273.9 88.5 0.46 281.6 91.8 0.48 0.664 0.9999 1483656 ChemDiv1_010096 CCC(=O)Nc1c(nc2ccc(C)cn12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K21 compound treatment 276.9 91.5 0.48 285.6 95.8 0.5 0.6897 0.9998 1412753 ChemDiv1_010097 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(OCC)cc3)c4ccccc24)c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K22 compound treatment 278.6 93.2 0.49 278.2 88.4 0.46 0.6688 0.9996 1134589 ChemDiv1_010098 CCC(=O)Nc1c(nc2ccc(C)cn12)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K23 mock treatment 277.1 91.7 0.48 281.1 91.3 0.47 0.6739 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 K24 mock treatment 77.1 -108.0 -0.56 80.5 -109.0 -0.57 -0.8011 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L01 compound treatment 281.6 96.2 0.5 289.1 99.3 0.52 0.72 0.9999 1974833 ChemDiv1_010099 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L02 compound treatment 282.6 97.2 0.51 287.3 97.5 0.51 0.717 1.0 1789122 ChemDiv1_010100 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)c2ccccc2N3C(=O)C4CC=CCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L03 compound treatment 276.7 91.3 0.48 283.8 94.0 0.49 0.6824 0.9999 1424870 ChemDiv1_010101 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L04 compound treatment 294.0 109.0 0.57 299.5 110.0 0.57 0.8039 1.0 1974834 ChemDiv1_010102 NS(=O)(=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L05 compound treatment 279.4 94.0 0.49 291.4 102.0 0.53 0.7203 0.9993 1439504 ChemDiv1_010103 CCC(C)C(=O)N(C1CC(C)N(C(=O)C(C)CC)c2ccccc12)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L06 compound treatment 277.7 92.3 0.48 290.0 100.0 0.52 0.7089 0.9992 1974835 ChemDiv1_010104 COc1ccc(cc1OC)C2CC(=NN2c3nc(cs3)c4ccc(cc4)S(=O)(=O)N5CCOCC5)c6cccs6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L07 compound treatment 278.9 93.5 0.49 291.6 102.0 0.53 0.7192 0.9992 1704151 ChemDiv1_010105 COc1ccc2nc(NC(=O)CCN3C(=O)c4ccccc4C3=O)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L08 compound treatment 281.0 95.6 0.5 289.5 99.7 0.52 0.7192 0.9998 1209552 ChemDiv1_010106 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3OC)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L09 compound treatment 275.5 90.1 0.47 288.9 99.1 0.52 0.6967 0.999 1974836 ChemDiv1_010107 NC(=O)CSc1nc(cc(c2cccs2)c1C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L10 compound treatment 345.9 161.0 0.84 358.4 169.0 0.88 1.2118 0.9997 1456980 ChemDiv1_010108 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L11 compound treatment 274.0 88.6 0.46 288.1 98.3 0.51 0.6882 0.9988 1974837 ChemDiv1_010109 COc1ccc(NC(=O)CSc2nc3CCN(C)Cc3c(c2C#N)c4ccccc4)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L12 compound treatment 148.1 -37.3 -0.19 143.7 -46.1 -0.24 -0.3069 -0.9946 1718555 ChemDiv1_010110 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4cn(C)c5ccccc45)c(=O)n23)C(=O)Nc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L13 compound treatment 276.4 91.0 0.47 290.9 101.0 0.53 0.7074 0.9987 1974838 ChemDiv1_010111 CC(CNC(=O)c1sc2ccccc2c1Cl)NC(=O)c3sc4ccccc4c3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L14 compound treatment 344.2 159.0 0.83 311.3 122.0 0.63 1.0325 0.991 1974839 ChemDiv1_010112 Clc1cccc(N2C(=O)/C(=C/c3ccc(o3)N4CCOCC4)/C(=O)NC2=S)c1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L15 compound treatment 275.8 90.4 0.47 291.4 102.0 0.53 0.707 0.9984 1353875 ChemDiv1_010113 O=C(COC(=O)c1ccccc1N2C(=O)C3C4CC(C=C4)C3C2=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L16 compound treatment 283.4 98.0 0.51 291.2 101.0 0.53 0.7343 0.9999 1925289 ChemDiv1_010114 COc1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L17 compound treatment 277.0 91.6 0.48 289.8 100.0 0.52 0.7056 0.9991 1271068 ChemDiv1_010115 O=C(COC(=O)c1cc(cc(c1)C(=O)OCC(=O)c2ccccc2)N3C(=O)C4CC=CCC4C3=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L18 compound treatment 276.6 91.2 0.48 288.5 98.7 0.51 0.6993 0.9993 1974840 ChemDiv1_010116 Fc1cc(Br)ccc1NC(=O)c2ccc3OCCOc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L19 compound treatment 277.2 91.8 0.48 281.4 91.6 0.48 0.6754 1.0 1226960 ChemDiv1_010117 Cc1ccc2nc(cc(C(=O)N3CCOCC3)c2c1)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L20 compound treatment 279.5 94.1 0.49 287.0 97.2 0.51 0.7045 0.9999 1882552 ChemDiv1_010118 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L21 compound treatment 271.4 86.0 0.45 281.0 91.2 0.47 0.6526 0.9996 1851893 ChemDiv1_010119 Cc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L22 compound treatment 271.1 85.7 0.45 280.8 91.0 0.47 0.6507 0.9996 1974841 ChemDiv1_010120 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L23 mock treatment 283.4 98.0 0.51 281.7 91.9 0.48 0.6994 0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 L24 mock treatment 78.4 -107.0 -0.56 83.2 -107.0 -0.55 -0.7864 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M01 compound treatment 284.5 99.1 0.52 294.7 105.0 0.55 0.7512 0.9996 1482348 ChemDiv1_010121 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M02 compound treatment 277.1 91.7 0.48 287.1 97.3 0.51 0.696 0.9996 1974842 ChemDiv1_010122 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3cc(ccc3Cl)[N+](=O)[O-])cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M03 compound treatment 282.9 97.5 0.51 288.0 98.2 0.51 0.7207 1.0 1141356 ChemDiv1_010123 COC(=O)C1=C(C)N(C)C(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M04 compound treatment 280.8 95.4 0.5 291.1 101.0 0.53 0.7244 0.9996 1524225 ChemDiv1_010124 CCc1ccc(cc1)S(=O)(=O)Nc2cc3c(C(=O)OC)c(oc3c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M05 compound treatment 279.5 94.1 0.49 293.9 104.0 0.54 0.7298 0.9988 1695092 ChemDiv1_010125 COc1ccc(cc1)c2nn(cc2C3NC(=O)NC(=C3C(=O)OC(C)C)C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M06 compound treatment 281.9 96.5 0.5 286.7 96.9 0.5 0.7122 1.0 1506896 ChemDiv1_010126 COCc1oc2c(cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc24)c1C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M07 compound treatment 328.6 143.0 0.75 335.4 146.0 0.76 1.0635 1.0 1974843 ChemDiv1_010127 O=C/1N(Cc2ccco2)C(=S)S\C1=C/c3c(NCCc4ccccc4)nc5ccccn5c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M08 compound treatment 281.7 96.3 0.5 290.1 100.0 0.52 0.724 0.9998 1616725 ChemDiv1_010128 COc1ccc(cc1)c2cc(C#N)nc(n2)N3CCN(CC3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M09 compound treatment 366.7 181.0 0.95 373.0 183.0 0.95 1.3422 1.0 1974844 ChemDiv1_010129 CC1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C\4/SC(=S)N(CC5CCCO5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M10 compound treatment 276.8 91.4 0.48 290.1 100.0 0.52 0.7059 0.999 1701406 ChemDiv1_010130 COc1ccc(cc1OC)c2cn3cccc(C)c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M11 compound treatment 278.9 93.5 0.49 290.8 101.0 0.53 0.7162 0.9993 1232501 ChemDiv1_010131 COc1ccc(cc1Cl)c2nn(cc2C3NC(=O)NC(=C3C(=O)OCC=C)C)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M12 compound treatment 276.3 90.9 0.47 290.4 101.0 0.52 0.7052 0.9988 1501090 ChemDiv1_010132 CC(C)OC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3cccs3)c4ccccc4)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M13 compound treatment 277.5 92.1 0.48 289.6 99.8 0.52 0.7067 0.9993 1140070 ChemDiv1_010133 CCNc1nc(NC(C)C)nc(Oc2ccc(OCC)nn2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M14 compound treatment 276.3 90.9 0.47 289.8 100.0 0.52 0.703 0.999 1974845 ChemDiv1_010134 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M15 compound treatment 280.8 95.4 0.5 290.1 100.0 0.52 0.7207 0.9997 1974846 ChemDiv1_010135 O=C1NC(=O)/C(=C\c2ccc(Sc3ccccc3)o2)/N1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M16 compound treatment 296.1 111.0 0.58 306.1 116.0 0.6 0.8359 0.9997 1974847 ChemDiv1_010136 CCOc1ccc(cc1[N+](=O)[O-])c2nn(cc2/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M17 compound treatment 277.6 92.2 0.48 287.4 97.6 0.51 0.6989 0.9996 1529063 ChemDiv1_010137 CCOC(=O)CN1C(=O)C(O)(C(C)C(=O)c2ccccc2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M18 compound treatment 279.7 94.3 0.49 290.2 100.0 0.52 0.717 0.9996 1974848 ChemDiv1_010138 COc1nc(cc(c1C#N)c2ccc(cc2)C(C)C)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M19 compound treatment 274.9 89.5 0.47 282.2 92.4 0.48 0.6699 0.9999 1150047 ChemDiv1_010139 CCCc1oc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M20 compound treatment 277.7 92.3 0.48 285.2 95.4 0.5 0.6912 0.9999 1693108 ChemDiv1_010140 Cc1ccn2c(NC(=O)c3ccco3)c(nc2c1)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M21 compound treatment 279.7 94.3 0.49 283.9 94.1 0.49 0.6938 1.0 1575724 ChemDiv1_010141 CCCc1oc2c(cc(NS(=O)(=O)c3cc(C)ccc3C)c4ccccc24)c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M22 compound treatment 280.6 95.2 0.5 283.8 94.0 0.49 0.6968 1.0 1224427 ChemDiv1_010142 Cc1ccc(cc1)c2nc3ccc(C)cn3c2NC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M23 mock treatment 276.6 91.2 0.48 281.2 91.4 0.48 0.6725 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 M24 mock treatment 193.3 7.93 0.04 190.9 1.1 0.01 0.0333 0.7973 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N01 compound treatment 284.4 99.0 0.52 284.8 95.0 0.49 0.7145 0.9997 1974849 ChemDiv1_010143 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3ccco3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N02 compound treatment 280.5 95.1 0.5 290.0 100.0 0.52 0.7192 0.9997 1189545 ChemDiv1_010144 CC1=CCC2C(C1)C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N03 compound treatment 281.8 96.4 0.5 288.3 98.5 0.51 0.7177 1.0 1172800 ChemDiv1_010145 CC(C)C(=O)N1C(C)CC(N(C(=O)c2ccc(F)cc2)c3ccccc3)c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N04 compound treatment 287.0 102.0 0.53 289.7 99.9 0.52 0.7421 0.9999 1312065 ChemDiv1_010146 NS(=O)(=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)c3ccccc3)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N05 compound treatment 280.9 95.5 0.5 286.0 96.2 0.5 0.706 1.0 1322921 ChemDiv1_010147 COc1nc(Nc2nc3ccccc3c(=O)[nH]2)nc4ccc(C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N06 compound treatment 280.6 95.2 0.5 290.4 101.0 0.52 0.721 0.9997 1974850 ChemDiv1_010148 CCN(CC)S(=O)(=O)c1ccc(cc1)c2csc(n2)N3N=C(CC3c4ccco4)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N07 compound treatment 276.3 90.9 0.47 285.4 95.6 0.5 0.6868 0.9997 1974851 ChemDiv1_010149 COc1ccc(Nc2nc(Cl)nc(Nc3ccc(OC)cc3OC)n2)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N08 compound treatment 277.8 92.4 0.48 288.8 99.0 0.51 0.7048 0.9995 1305096 ChemDiv1_010150 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N09 compound treatment 277.8 92.4 0.48 286.0 96.2 0.5 0.6945 0.9998 1974852 ChemDiv1_010151 COC(=O)CSc1nc(cc(c2cccs2)c1C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N10 compound treatment 280.3 94.9 0.5 288.9 99.1 0.52 0.7144 0.9998 1149290 ChemDiv1_010152 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5cccc(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N11 compound treatment 297.5 112.0 0.58 307.7 118.0 0.61 0.847 0.9997 1297767 ChemDiv1_010153 COc1ccc(cc1OC)C(=O)c2sc3nc(C)cc(c4cccs4)c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N12 compound treatment 278.9 93.5 0.49 287.4 97.6 0.51 0.7037 0.9998 1974853 ChemDiv1_010154 CN1C(=O)N(C)C(=O)C(=Cc2ccc(o2)c3ccc(C)cc3Br)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N13 compound treatment 274.9 89.5 0.47 287.0 97.2 0.51 0.6875 0.9992 1697240 ChemDiv1_010155 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N14 compound treatment 273.4 88.0 0.46 287.7 97.9 0.51 0.6846 0.9987 1974854 ChemDiv1_010156 CN(C1=NS(=O)(=O)c2ccccc12)c3ccc(OC(=O)C4CN(C(=O)C4)c5ccccc5)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N15 compound treatment 276.1 90.7 0.47 289.0 99.2 0.52 0.6993 0.9991 1464179 ChemDiv1_010157 O=C(COC(=O)c1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N16 compound treatment 282.3 96.9 0.51 288.3 98.5 0.51 0.7196 1.0 1974855 ChemDiv1_010158 CCN(CC)c1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N17 compound treatment 278.3 92.9 0.48 283.5 93.7 0.49 0.6872 1.0 1974856 ChemDiv1_010159 Clc1ccc(cc1)C(=O)COC(=O)c2ccccc2N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N18 compound treatment 285.0 99.6 0.52 293.4 104.0 0.54 0.7483 0.9998 1417498 ChemDiv1_010160 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N19 compound treatment 275.4 90.0 0.47 284.1 94.3 0.49 0.6787 0.9998 1391216 ChemDiv1_010161 COc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4cc(C)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N20 compound treatment 278.2 92.8 0.48 285.8 96.0 0.5 0.6953 0.9999 1882557 ChemDiv1_010162 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4cc(OC)c(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N21 compound treatment 276.3 90.9 0.47 281.9 92.1 0.48 0.6739 1.0 1851897 ChemDiv1_010163 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N22 compound treatment 275.2 89.8 0.47 276.6 86.8 0.45 0.6504 0.9998 1974857 ChemDiv1_010164 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N23 mock treatment 278.3 92.9 0.48 280.7 90.9 0.47 0.6769 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 N24 mock treatment 175.8 -9.57 -0.05 189.7 -0.1 0.0 -0.0357 -0.7144 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O01 compound treatment 283.7 98.3 0.51 284.5 94.7 0.49 0.7108 0.9998 1974858 ChemDiv1_010165 COC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Br)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O02 compound treatment 280.7 95.3 0.5 284.0 94.2 0.49 0.6979 1.0 1247959 ChemDiv1_010166 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O03 compound treatment 281.9 96.5 0.5 283.1 93.3 0.48 0.699 0.9998 1546645 ChemDiv1_010167 COC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)cc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O04 compound treatment 283.6 98.2 0.51 288.4 98.6 0.51 0.7248 1.0 1523252 ChemDiv1_010168 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(OC)cc3)c4ccccc24)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O05 compound treatment 283.0 97.6 0.51 287.7 97.9 0.51 0.72 1.0 1402904 ChemDiv1_010169 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)c(Br)c3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O06 compound treatment 278.9 93.5 0.49 286.0 96.2 0.5 0.6986 0.9999 1203266 ChemDiv1_010170 COCc1oc2c(cc(NS(=O)(=O)c3ccc(Br)cc3)c4ccccc24)c1C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O07 compound treatment 340.0 155.0 0.81 341.7 152.0 0.79 1.1287 0.9999 1974859 ChemDiv1_010171 COCCCN1C(=O)/C(=C/c2c(NCCCn3ccnc3)nc4ccccn4c2=O)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O08 compound treatment 277.8 92.4 0.48 293.0 103.0 0.54 0.7203 0.9986 1974860 ChemDiv1_010172 COC(=O)c1ccccc1OCCCn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O09 compound treatment 274.8 89.4 0.47 289.9 100.0 0.52 0.6978 0.9985 1586912 ChemDiv1_010173 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC=C)c4ccccc34)c(=O)n2C1c5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O10 compound treatment 275.2 89.8 0.47 286.4 96.6 0.5 0.6864 0.9994 1924477 ChemDiv1_010174 COCCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(F)cc3)c4ccccc4)C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O11 compound treatment 280.6 95.2 0.5 286.2 96.4 0.5 0.7056 1.0 1552944 ChemDiv1_010175 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(C)cc3)c4ccccc4)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O12 compound treatment 278.4 93.0 0.49 285.3 95.5 0.5 0.6942 0.9999 1974861 ChemDiv1_010176 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(c3)[N+](=O)[O-])C(=O)OCCOC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O13 compound treatment 279.2 93.8 0.49 287.1 97.3 0.51 0.7037 0.9999 1974862 ChemDiv1_010177 CCNc1nc(NC(C)C)nc(Oc2ccc(OCCOc3ccccc3)nn2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O14 compound treatment 280.1 94.7 0.49 289.0 99.2 0.52 0.714 0.9998 1974863 ChemDiv1_010178 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O15 compound treatment 279.2 93.8 0.49 288.1 98.3 0.51 0.7074 0.9998 1974864 ChemDiv1_010179 [O-][N+](=O)c1ccc(COc2ccc3ccccc3c2/C=C\4/NC(=O)NC4=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O16 compound treatment 277.1 91.7 0.48 287.7 97.9 0.51 0.6982 0.9995 1974865 ChemDiv1_010180 COc1nc(cc(c1C#N)c2ccc(C)cc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O17 compound treatment 277.8 92.4 0.48 293.2 103.0 0.54 0.721 0.9985 1238374 ChemDiv1_010181 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccc(OC)cc2OC)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O18 compound treatment 274.2 88.8 0.46 282.6 92.8 0.48 0.6688 0.9998 1032503 ChemDiv1_010182 COC(=O)CN1C(=O)c2ccccc2S1(=O)=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O19 compound treatment 275.0 89.6 0.47 287.8 98.0 0.51 0.6908 0.9991 1645934 ChemDiv1_010183 CCCc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3C)cc2c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O20 compound treatment 275.3 89.9 0.47 284.9 95.1 0.49 0.6813 0.9997 1734563 ChemDiv1_010184 COc1ccc(cc1)C(=O)Nc2c(nc3ccc(C)cn23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O21 compound treatment 274.9 89.5 0.47 278.1 88.3 0.46 0.6548 1.0 1974866 ChemDiv1_010185 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])c4ccccc24)c1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O22 compound treatment 279.9 94.5 0.49 281.9 92.1 0.48 0.6872 0.9999 1336596 ChemDiv1_010186 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)S(=O)(=O)N(C)C)c4ccccc4)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O23 mock treatment 280.6 95.2 0.5 284.4 94.6 0.49 0.699 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 O24 mock treatment 98.2 -87.2 -0.45 98.6 -91.2 -0.47 -0.6567 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P01 compound treatment 286.4 101.0 0.53 286.2 96.4 0.5 0.727 0.9997 1264656 ChemDiv1_010187 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(Cl)c3)c4ccccc4)C(=O)OC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P02 compound treatment 282.5 97.1 0.51 286.3 96.5 0.5 0.713 1.0 1569526 ChemDiv1_010188 CC1=CCC2C(C1)C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P03 compound treatment 284.1 98.7 0.52 284.3 94.5 0.49 0.7115 0.9997 1557380 ChemDiv1_010189 CCCC(=O)N1C(C)CC(Nc2ccccc2C)c3cccc(C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P04 compound treatment 282.1 96.7 0.5 288.2 98.4 0.51 0.7185 1.0 1786202 ChemDiv1_010190 COc1ccccc1NC(=O)Cn2cnc(n2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P05 compound treatment 281.5 96.1 0.5 288.8 99.0 0.51 0.7185 0.9999 1243634 ChemDiv1_010191 O=C(CSc1nc2ccccc2o1)N3CCc4ccccc4C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P06 compound treatment 284.2 98.8 0.52 287.0 97.2 0.51 0.7218 0.9999 1974867 ChemDiv1_010192 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P07 compound treatment 279.2 93.8 0.49 287.2 97.4 0.51 0.7041 0.9999 1406825 ChemDiv1_010193 CCC(=O)Nc1ccc(Nc2nc(Cl)nc(Nc3ccc(NC(=O)CC)cc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P08 compound treatment 335.0 150.0 0.78 337.8 148.0 0.77 1.0959 1.0 1534172 ChemDiv1_010194 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(cc3)N(C)C)c(=O)n2C1c4ccc(OC)cc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P09 compound treatment 280.6 95.2 0.5 286.0 96.2 0.5 0.7049 1.0 1974868 ChemDiv1_010195 COC(=O)CSc1nc(cc(c1C#N)c2ccc(OC)cc2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P10 compound treatment 278.5 93.1 0.49 293.9 104.0 0.54 0.7262 0.9986 1574047 ChemDiv1_010196 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(OC)cc3OC)c(=O)n2C1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P11 compound treatment 280.5 95.1 0.5 289.3 99.5 0.52 0.7166 0.9998 1974869 ChemDiv1_010197 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3c2c(C)nn3c4cccc(Cl)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P12 compound treatment 276.7 91.3 0.48 284.7 94.9 0.49 0.6857 0.9998 1974870 ChemDiv1_010198 OC(=O)c1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(F)c(c4)[N+](=O)[O-])sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P13 compound treatment 281.5 96.1 0.5 290.7 101.0 0.52 0.7255 0.9997 1709606 ChemDiv1_010199 CN1C2CCC1C=C(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5cc(Cl)cc(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P14 compound treatment 283.7 98.3 0.51 288.8 99.0 0.51 0.7266 1.0 1974871 ChemDiv1_010200 COc1ccccc1N(CCOC(=O)c2ccccc2)S(=O)(=O)c3ccc(NC4=NS(=O)(=O)c5ccccc45)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P15 compound treatment 279.4 94.0 0.49 289.0 99.2 0.52 0.7115 0.9997 1780116 ChemDiv1_010201 [O-][N+](=O)c1cccc(c1)C(=O)COC(=O)c2cccc(c2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P16 compound treatment 334.2 149.0 0.78 326.7 137.0 0.71 1.0522 0.9991 1974872 ChemDiv1_010202 CCc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(O)c(OC)c3)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P17 compound treatment 274.2 88.8 0.46 287.6 97.8 0.51 0.6871 0.9989 1974873 ChemDiv1_010203 Cc1ccc(cc1C)C(=O)COC(=O)C(CCCCN2C(=O)C3C4CC(C=C4)C3C2=O)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P18 compound treatment 374.2 189.0 0.99 360.4 171.0 0.89 1.3236 0.9986 1974874 ChemDiv1_010204 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc([N+](=O)[O-])c3O)c(=O)n2C1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P19 compound treatment 279.9 94.5 0.49 281.1 91.3 0.47 0.6843 0.9998 1974875 ChemDiv1_010205 CC1CCC2C(C1)C(=O)N(CN(C(=O)C)c3ccc(C)c(Cl)c3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P20 compound treatment 283.2 97.8 0.51 287.7 97.9 0.51 0.7207 1.0 1882633 ChemDiv1_010206 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4cccc(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P21 compound treatment 273.9 88.5 0.46 283.3 93.5 0.49 0.6702 0.9997 1974876 ChemDiv1_010207 [O-][N+](=O)c1cc(ccc1Cl)C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4CC=CCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P22 compound treatment 280.0 94.6 0.49 285.0 95.2 0.49 0.699 1.0 1974877 ChemDiv1_010208 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cc(ccc4N5CCN(C)CC5)[N+](=O)[O-])c(=O)n23)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P23 mock treatment 277.7 92.3 0.48 283.1 93.3 0.48 0.6835 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.615 P24 mock treatment 89.7 -95.7 -0.5 96.5 -93.3 -0.48 -0.6958 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A01 compound treatment 290.1 104.0 0.54 295.0 107.0 0.56 0.7776 0.9999 1974878 ChemDiv1_010209 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccn3c4ccc(cc4)[N+](=O)[O-])c(=O)n2C1c5cccc(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A02 compound treatment 280.4 94.5 0.49 289.1 101.0 0.53 0.7201 0.9995 1974879 ChemDiv1_010210 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(F)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A03 compound treatment 281.5 95.6 0.5 287.4 99.4 0.52 0.7179 0.9998 1586414 ChemDiv1_010211 Clc1ccc(cc1)c2nc(NCC3CCCO3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A04 compound treatment 285.0 99.1 0.52 290.5 103.0 0.53 0.7422 0.9999 1974880 ChemDiv1_010212 CCN/1C(=O)CC(S\C1=N/c2ccc(cc2)C(=O)OC)C(=O)Nc3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A05 compound treatment 279.5 93.6 0.49 285.6 97.6 0.51 0.7039 0.9998 1974881 ChemDiv1_010213 [O-][N+](=O)c1ccc(OCC(=O)Nc2nnc[nH]2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A06 compound treatment 275.5 89.6 0.47 287.6 99.6 0.52 0.6965 0.9987 1974882 ChemDiv1_010214 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3cccc(Cl)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A07 compound treatment 278.7 92.8 0.48 288.0 100.0 0.52 0.7098 0.9994 1974883 ChemDiv1_010215 COc1ccc(Oc2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A08 compound treatment 278.3 92.4 0.48 287.7 99.7 0.52 0.7072 0.9993 1974884 ChemDiv1_010216 CN(C1=NC(=O)C(S1)C2SC(=O)NC2=O)c3ccc(O)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A09 compound treatment 278.5 92.6 0.48 292.3 104.0 0.54 0.7249 0.9983 1196330 ChemDiv1_010217 COc1ccc(Oc2coc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A10 compound treatment 278.2 92.3 0.48 290.4 102.0 0.53 0.7168 0.9987 1238281 ChemDiv1_010218 CCOc1ccc(cc1Br)C(=O)Nc2ccc3oc(nc3c2)c4ccncc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A11 compound treatment 276.2 90.3 0.47 286.1 98.1 0.51 0.6936 0.9992 1974885 ChemDiv1_010219 CCC1CCCCN1C(=O)CCN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A12 compound treatment 277.2 91.3 0.48 284.3 96.3 0.5 0.6907 0.9997 1326128 ChemDiv1_010220 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc3nc(oc3c2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A13 compound treatment 276.0 90.1 0.47 290.4 102.0 0.53 0.7087 0.9981 1974886 ChemDiv1_010221 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N3CCN(CC3)c4ccccc4)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A14 compound treatment 274.5 88.6 0.46 286.5 98.5 0.51 0.6888 0.9987 1974887 ChemDiv1_010222 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A15 compound treatment 273.6 87.7 0.46 286.0 98.0 0.51 0.6837 0.9985 1974888 ChemDiv1_010223 Cc1cccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A16 compound treatment 277.1 91.2 0.48 286.4 98.4 0.51 0.698 0.9993 1974889 ChemDiv1_010224 Brc1ccc(OCCSc2nc3ccccc3[nH]2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A17 compound treatment 275.7 89.8 0.47 288.7 101.0 0.52 0.7013 0.9984 1974890 ChemDiv1_010225 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cccc(c3)C(F)(F)F)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A18 compound treatment 280.8 94.9 0.49 282.6 94.6 0.49 0.6977 1.0 1974891 ChemDiv1_010226 CC(C)OC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A19 compound treatment 280.2 94.3 0.49 286.6 98.6 0.51 0.7102 0.9998 1785253 ChemDiv1_010227 [O-][N+](=O)c1ccc2[nH]c3C(=O)NCCc3c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A20 compound treatment 276.3 90.4 0.47 283.0 95.0 0.49 0.6826 0.9997 1974892 ChemDiv1_010228 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(cc3)N4CCOCC4)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A21 compound treatment 276.1 90.2 0.47 281.8 93.8 0.49 0.6774 0.9998 1974893 ChemDiv1_010229 CN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccc(cc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A22 compound treatment 273.3 87.4 0.46 278.6 90.6 0.47 0.6554 0.9999 1158633 ChemDiv1_010230 CCOC(=O)c1c(CSc2cccs2)n(C)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A23 mock treatment 277.8 91.9 0.48 279.5 91.5 0.48 0.6753 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 A24 mock treatment 79.6 -106.0 -0.55 75.0 -113.0 -0.59 -0.8075 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B01 compound treatment 286.1 100.0 0.52 285.9 97.9 0.51 0.7294 0.9999 1187156 ChemDiv1_010231 O=C(Nc1ccc2oc(nc2c1)c3ccncc3)c4cccc(OCc5ccccc5)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B02 compound treatment 281.9 96.0 0.5 289.3 101.0 0.53 0.7264 0.9997 1294338 ChemDiv1_010232 CCOC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(OC(=O)C)cc4OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B03 compound treatment 278.3 92.4 0.48 290.0 102.0 0.53 0.7157 0.9989 1974894 ChemDiv1_010233 CS(=O)(=O)N(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3cc(ccc3Cl)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B04 compound treatment 273.4 87.5 0.46 286.1 98.1 0.51 0.6833 0.9985 1935793 ChemDiv1_010234 Oc1cc(Cl)c([N+](=O)[O-])c2C3C=CCC3C(Nc12)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B05 compound treatment 278.6 92.7 0.48 286.3 98.3 0.51 0.7032 0.9996 1654902 ChemDiv1_010235 COc1cc(cc(OC)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc(C)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B06 compound treatment 351.0 165.0 0.86 351.7 164.0 0.85 1.2106 1.0 1974895 ChemDiv1_010236 CC(N1C(=O)/C(=C\c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B07 compound treatment 274.4 88.5 0.46 285.2 97.2 0.51 0.6837 0.999 1974896 ChemDiv1_010237 COC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OC)c3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B08 compound treatment 318.8 133.0 0.69 333.2 145.0 0.75 1.0239 0.9991 1974897 ChemDiv1_010238 CC1CN(CC(C)O1)c2nc3c(C)cccn3c(=O)c2/C=C\4/SC(=S)N(C5CCCCC5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B09 compound treatment 276.6 90.7 0.47 287.4 99.4 0.52 0.6999 0.999 1158624 ChemDiv1_010239 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B10 compound treatment 272.6 86.7 0.45 287.2 99.2 0.52 0.6844 0.9978 1212617 ChemDiv1_010240 OC1(CC(=O)c2ccco2)C(=O)Nc3ccc(Br)cc31 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B11 compound treatment 280.4 94.5 0.49 282.7 94.7 0.49 0.6966 1.0 1974898 ChemDiv1_010241 CN(C)c1nc(OCCOC(=O)Nc2sc(=S)n(C)c2C)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B12 compound treatment 274.2 88.3 0.46 284.2 96.2 0.5 0.6793 0.9991 1231597 ChemDiv1_010242 CN(C)c1ccc(cc1)C(=O)CC2(O)C(=O)Nc3ccc(C)cc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B13 compound treatment 274.2 88.3 0.46 288.1 100.0 0.52 0.6936 0.9981 1974899 ChemDiv1_010243 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B14 compound treatment 273.1 87.2 0.45 288.8 101.0 0.52 0.6921 0.9975 1974900 ChemDiv1_010244 O=C(Nc1ccccc1Sc2ncnc3sc4CCCCc4c23)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B15 compound treatment 275.4 89.5 0.47 292.2 104.0 0.54 0.7131 0.9972 1974901 ChemDiv1_010245 Cc1cc(OCc2nc(no2)c3ccc(Br)cc3)ccc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B16 compound treatment 274.9 89.0 0.46 285.7 97.7 0.51 0.6873 0.999 1974902 ChemDiv1_010246 Cc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3cccc(Br)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B17 compound treatment 278.5 92.6 0.48 285.3 97.3 0.51 0.6992 0.9997 1974903 ChemDiv1_010247 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)ccc1OCC#C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B18 compound treatment 275.1 89.2 0.47 283.8 95.8 0.5 0.6811 0.9994 1974904 ChemDiv1_010248 Cc1ccc(cc1)S(=O)(=O)N2CCN(CCNC(=O)C(=O)NCc3ccccc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B19 compound treatment 273.3 87.4 0.46 282.8 94.8 0.49 0.6708 0.9992 1974905 ChemDiv1_010249 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cc(C)c(Cl)c(C)c3)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B20 compound treatment 272.9 87.0 0.45 282.9 94.9 0.49 0.6697 0.9991 1974906 ChemDiv1_010250 CC(C)c1ccc(C#N)c(SCC(=O)Nc2ccccc2C(=O)O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B21 compound treatment 278.0 92.1 0.48 278.7 90.7 0.47 0.6731 1.0 1974907 ChemDiv1_010251 CC/N=C/1\SC(CC(=O)Nc2sc(C)c(C)c2C(=O)OC)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B22 compound treatment 273.1 87.2 0.45 277.5 89.5 0.47 0.6506 0.9999 1612904 ChemDiv1_010252 CC(C)c1ccc(C#N)c(SCC(=O)Nc2cccc(c2)C(=O)O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B23 mock treatment 278.9 93.0 0.48 280.2 92.2 0.48 0.6819 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 B24 mock treatment 77.0 -109.0 -0.57 77.5 -110.0 -0.57 -0.8079 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C01 compound treatment 287.3 101.0 0.53 294.6 107.0 0.55 0.7658 0.9997 1941722 ChemDiv1_010253 COc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccncc3)C2=O)ccc1OCc4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C02 compound treatment 275.6 89.7 0.47 291.4 103.0 0.54 0.7109 0.9976 1974908 ChemDiv1_010254 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cc(Cl)cc(Cl)c3)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C03 compound treatment 274.4 88.5 0.46 289.0 101.0 0.53 0.6976 0.9979 1974909 ChemDiv1_010255 COCCN(CCOC)c1nc(nc2ccccc12)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C04 compound treatment 275.7 89.8 0.47 290.3 102.0 0.53 0.7072 0.998 1974910 ChemDiv1_010256 CN/1C(=O)CC(S\C1=N/c2ccc(Br)cc2)C(=O)Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C05 compound treatment 277.1 91.2 0.48 293.3 105.0 0.55 0.7234 0.9975 1974911 ChemDiv1_010257 COc1cc(C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)c(Br)c(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C06 compound treatment 276.6 90.7 0.47 289.2 101.0 0.53 0.7065 0.9986 1974912 ChemDiv1_010258 CCCOc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(C)c(C)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C07 compound treatment 273.1 87.2 0.45 291.0 103.0 0.54 0.7002 0.9967 1950251 ChemDiv1_010259 CCOC(=O)Oc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C08 compound treatment 278.6 92.7 0.48 289.3 101.0 0.53 0.7142 0.9991 1974913 ChemDiv1_010260 CCOc1ccc(/N=C/2\NC(=O)S\C2=C/3\C(=O)Nc4ccc(Br)cc34)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C09 compound treatment 280.7 94.8 0.49 292.4 104.0 0.54 0.7334 0.9989 1974914 ChemDiv1_010261 Brc1ccccc1NC(=O)CCCN2C(=O)/C(=C\c3cccs3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C10 compound treatment 275.1 89.2 0.47 292.2 104.0 0.54 0.712 0.9971 1924229 ChemDiv1_010262 Cc1ccc(OCc2nc(no2)c3ccc(Cl)cc3)c(Br)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C11 compound treatment 278.4 92.5 0.48 287.8 99.8 0.52 0.708 0.9993 1974915 ChemDiv1_010263 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccccc3O)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C12 compound treatment 274.5 88.6 0.46 298.5 111.0 0.57 0.7329 0.9942 1274587 ChemDiv1_010264 COc1ccccc1N2CCN(Cc3cc(COCc4ccccc4)c5cccnc5c3O)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C13 compound treatment 275.7 89.8 0.47 287.1 99.1 0.52 0.6954 0.9989 1974916 ChemDiv1_010265 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3ccc(OC)c(OC)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C14 compound treatment 271.3 85.4 0.45 284.8 96.8 0.5 0.6708 0.9981 1722632 ChemDiv1_010266 Clc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C15 compound treatment 276.8 90.9 0.47 149.0 -39.0 -0.2 0.1919 0.3723 1389931 ChemDiv1_010267 CCC(Sc1nc2ccccc2o1)C(=O)Nc3cc(C)on3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C16 compound treatment 273.2 87.3 0.46 289.8 102.0 0.53 0.6961 0.9972 1302732 ChemDiv1_010268 O=C(Nc1nc2ccccc2n1CCOc3ccccc3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C17 compound treatment 278.3 92.4 0.48 288.3 100.0 0.52 0.7094 0.9992 1974917 ChemDiv1_010269 CCN/1C(=O)CC(S\C1=N/c2ccc(Br)cc2)C(=O)Nc3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C18 compound treatment 303.7 118.0 0.61 311.3 123.0 0.64 0.8877 0.9998 1974918 ChemDiv1_010270 COC(=O)c1cc(ccc1Cl)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C19 compound treatment 276.0 90.1 0.47 281.3 93.3 0.49 0.6752 0.9999 1974919 ChemDiv1_010271 COc1ccc2[nH]cc(CCN3C(=O)C4CCCCC4C3=O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C20 compound treatment 270.6 84.7 0.44 279.5 91.5 0.48 0.6487 0.9993 1974920 ChemDiv1_010272 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(O)c(OC)c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C21 compound treatment 272.9 87.0 0.45 279.8 91.8 0.48 0.6583 0.9997 1974921 ChemDiv1_010273 CCN/1C(=O)CC(S\C1=N/c2ccc(OC)cc2)C(=O)Nc3ccc(cc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C22 compound treatment 276.2 90.3 0.47 279.7 91.7 0.48 0.6701 1.0 1387424 ChemDiv1_010274 CCOC(=O)c1c(CSc2ccccc2)oc3cc(CN(C)C)c(O)c(Cl)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C23 mock treatment 278.0 92.1 0.48 279.1 91.1 0.47 0.6745 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 C24 mock treatment 76.9 -109.0 -0.57 81.2 -107.0 -0.56 -0.7947 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D01 compound treatment 283.4 97.5 0.51 286.0 98.0 0.51 0.7198 1.0 1284668 ChemDiv1_010275 COc1ccc(cc1OC)c2cn3ccc4ccccc4c3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D02 compound treatment 278.6 92.7 0.48 288.7 101.0 0.52 0.712 0.9992 1974922 ChemDiv1_010276 CC(=O)Oc1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D03 compound treatment 284.0 98.1 0.51 290.7 103.0 0.53 0.7393 0.9998 1974923 ChemDiv1_010277 FC(F)(F)c1ccc(Cl)c(c1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D04 compound treatment 244.8 58.9 0.31 264.4 76.4 0.4 0.498 0.9919 1456653 ChemDiv1_010278 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D05 compound treatment 278.5 92.6 0.48 290.8 103.0 0.53 0.7194 0.9987 1532111 ChemDiv1_010279 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D06 compound treatment 378.7 193.0 1.01 386.8 199.0 1.03 1.4418 0.9999 1974924 ChemDiv1_010280 OCCN1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C\4/SC(=S)N(CC5CCCO5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D07 compound treatment 278.6 92.7 0.48 289.1 101.0 0.53 0.7135 0.9991 1312882 ChemDiv1_010281 CC(=O)Oc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D08 compound treatment 349.5 164.0 0.85 347.5 160.0 0.83 1.1897 0.9999 1974925 ChemDiv1_010282 CN(Cc1ccccc1)c2nc3c(C)cccn3c(=O)c2/C=C\4/SC(=S)N(Cc5ccco5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D09 compound treatment 273.2 87.3 0.46 292.3 104.0 0.54 0.7053 0.9962 1560238 ChemDiv1_010283 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(CC)c3n2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D10 compound treatment 276.7 90.8 0.47 298.9 111.0 0.58 0.7425 0.9952 1201587 ChemDiv1_010284 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccccc4Cl)c5ccccc51 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D11 compound treatment 274.1 88.2 0.46 288.6 101.0 0.52 0.6951 0.9979 1974926 ChemDiv1_010285 CN(C)c1nc(SCCOC(=O)Nc2sc(=S)n(C)c2C)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D12 compound treatment 276.4 90.5 0.47 292.6 105.0 0.54 0.7182 0.9975 1266765 ChemDiv1_010286 COc1ccc(cc1OC)C2Oc3ccc(Cl)cc3C4CC(=NN42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D13 compound treatment 274.8 88.9 0.46 290.4 102.0 0.53 0.7043 0.9976 1974927 ChemDiv1_010287 Cc1c(NC(=O)CN(c2cccc(C)c2C)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D14 compound treatment 323.9 138.0 0.72 334.0 146.0 0.76 1.0456 0.9996 1974928 ChemDiv1_010288 Cc1ccc2nc(N3CCCCC3)c(/C=C/4\SC(=S)N(CC5CCCO5)C4=O)c(=O)n2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D15 compound treatment 282.9 97.0 0.51 296.6 109.0 0.56 0.7569 0.9985 1974929 ChemDiv1_010289 COc1ccc(cc1)C2CC(=O)NC(=N2)Nc3nc(C)c4ccc(C)cc4n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D16 compound treatment 271.3 85.4 0.45 289.1 101.0 0.53 0.6866 0.9966 1974930 ChemDiv1_010290 Cc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3cccc(C)c3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D17 compound treatment 276.4 90.5 0.47 284.3 96.3 0.5 0.6877 0.9996 1974931 ChemDiv1_010291 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)ccc1OCC#C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D18 compound treatment 278.8 92.9 0.48 287.3 99.3 0.52 0.7076 0.9995 1974932 ChemDiv1_010292 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(C)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D19 compound treatment 274.0 88.1 0.46 288.3 100.0 0.52 0.6936 0.998 1974933 ChemDiv1_010293 COC(=O)c1c(NC(=O)CC2S/C(=N\C)/N(C)C2=O)sc3CCCCc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D20 compound treatment 278.8 92.9 0.48 283.4 95.4 0.5 0.6933 0.9999 1974934 ChemDiv1_010294 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(F)c(F)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D21 compound treatment 272.8 86.9 0.45 283.4 95.4 0.5 0.6711 0.999 1974935 ChemDiv1_010295 CC/N=C/1\SC(CC(=O)Nc2sc3CCCCc3c2C(=O)OC)C(=O)N1CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D22 compound treatment 278.4 92.5 0.48 276.4 88.4 0.46 0.6661 0.9997 1697941 ChemDiv1_010296 CC(C)Cc1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D23 mock treatment 277.3 91.4 0.48 282.9 94.9 0.49 0.6859 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 D24 mock treatment 79.7 -106.0 -0.55 81.0 -107.0 -0.56 -0.7851 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E01 compound treatment 280.3 94.4 0.49 290.9 103.0 0.53 0.7264 0.9991 1246750 ChemDiv1_010297 CCOC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc4CC(C)CCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E02 compound treatment 281.6 95.7 0.5 291.9 104.0 0.54 0.7349 0.9992 1974936 ChemDiv1_010298 CCOC(=O)c1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccccc3F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E03 compound treatment 276.5 90.6 0.47 292.6 105.0 0.54 0.7186 0.9975 1137633 ChemDiv1_010299 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E04 compound treatment 281.8 95.9 0.5 288.2 100.0 0.52 0.722 0.9998 1974937 ChemDiv1_010300 CCN/1C(=O)CC(S\C1=N/c2ccc3OCOc3c2)C(=O)Nc4ccc(cc4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E05 compound treatment 302.0 116.0 0.61 288.7 101.0 0.52 0.7983 0.9974 1974938 ChemDiv1_010301 CC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E06 compound treatment 276.5 90.6 0.47 287.6 99.6 0.52 0.7002 0.999 1974939 ChemDiv1_010302 CCCOc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(OCC)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E07 compound treatment 284.8 98.9 0.52 299.3 111.0 0.58 0.7739 0.9984 1718575 ChemDiv1_010303 CC(C)(C)c1ccc(cc1)c2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E08 compound treatment 279.2 93.3 0.49 291.3 103.0 0.54 0.7238 0.9988 1974940 ChemDiv1_010304 COc1ccc(/N=C/2\NC(=O)S\C2=C/3\C(=O)Nc4ccc(Br)cc34)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E09 compound treatment 278.2 92.3 0.48 290.3 102.0 0.53 0.7164 0.9988 1974941 ChemDiv1_010305 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(CCO)c3ccccc3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E10 compound treatment 277.8 91.9 0.48 286.5 98.5 0.51 0.701 0.9994 1153499 ChemDiv1_010306 COc1ccc(cc1OC)c2noc(COc3ccc(C)cc3Br)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E11 compound treatment 279.6 93.7 0.49 291.6 104.0 0.54 0.7264 0.9988 1974942 ChemDiv1_010307 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)N3CCN(CC3)c4ccccc4)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E12 compound treatment 285.8 99.9 0.52 283.2 95.2 0.49 0.7184 0.9997 1436905 ChemDiv1_010308 COc1c(Cl)cc(Cl)cc1c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E13 compound treatment 272.0 86.1 0.45 289.3 101.0 0.53 0.6899 0.9968 1974943 ChemDiv1_010309 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cc(Cl)ccc3O)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E14 compound treatment 272.2 86.3 0.45 289.8 102.0 0.53 0.6925 0.9967 1266962 ChemDiv1_010310 Clc1ccccc1C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E15 compound treatment 274.4 88.5 0.46 290.6 103.0 0.53 0.7035 0.9974 1396098 ChemDiv1_010311 CCC(Sc1nncn1C)C(=O)Nc2cc(C)on2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E16 compound treatment 277.9 92.0 0.48 289.8 102.0 0.53 0.7135 0.9988 1974944 ChemDiv1_010312 NS(=O)(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc(cc4)C(=O)O)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E17 compound treatment 277.3 91.4 0.48 287.8 99.8 0.52 0.7039 0.9991 1974945 ChemDiv1_010313 CCN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccccc3OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E18 compound treatment 290.8 105.0 0.55 300.4 112.0 0.58 0.8 0.9995 1974946 ChemDiv1_010314 CCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E19 compound treatment 277.6 91.7 0.48 285.9 97.9 0.51 0.698 0.9995 1974947 ChemDiv1_010315 O=C1C2CCCCC2C(=O)N1c3ccc(cc3)S(=O)(=O)Nc4ncccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E20 compound treatment 275.5 89.6 0.47 280.0 92.0 0.48 0.6686 0.9999 1974948 ChemDiv1_010316 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3cc(Cl)c(O)c(OC)c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E21 compound treatment 273.3 87.4 0.46 284.3 96.3 0.5 0.6763 0.9989 1974949 ChemDiv1_010317 CCN/1C(=O)CC(S\C1=N/c2ccc(OC)cc2)C(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E22 compound treatment 274.9 89.0 0.46 277.1 89.1 0.46 0.6557 1.0 1170940 ChemDiv1_010318 CCOC(=O)c1c(CN(C)CCO)n(C)c2cc(Br)c(OC(=O)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E23 mock treatment 278.0 92.1 0.48 282.0 94.0 0.49 0.6852 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 E24 mock treatment 77.2 -109.0 -0.57 78.9 -109.0 -0.57 -0.802 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F01 compound treatment 283.3 97.4 0.51 287.6 99.6 0.52 0.7253 1.0 1974950 ChemDiv1_010319 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F02 compound treatment 277.1 91.2 0.48 288.5 101.0 0.52 0.7058 0.9989 1974951 ChemDiv1_010320 COc1cc([N+](=O)[O-])c2NC(C3CC=CC3c2c1)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F03 compound treatment 278.6 92.7 0.48 291.3 103.0 0.54 0.7216 0.9986 1974952 ChemDiv1_010321 COc1ccc(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F04 compound treatment 279.7 93.8 0.49 290.2 102.0 0.53 0.7216 0.9991 1974953 ChemDiv1_010322 OC(=O)C1CCC(CC1)N2C(=O)C3CCCCC3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F05 compound treatment 275.4 89.5 0.47 290.3 102.0 0.53 0.7061 0.9979 1513788 ChemDiv1_010323 CC(=O)Oc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F06 compound treatment 394.2 208.0 1.09 401.3 213.0 1.11 1.5523 0.9999 1974954 ChemDiv1_010324 COCCCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F07 compound treatment 277.4 91.5 0.48 289.3 101.0 0.53 0.7098 0.9988 1974955 ChemDiv1_010325 CCOC(=O)c1ccc(cc1)N2C=C(C(C(=C2)C(=O)OC)c3cc(Br)c(O)c(OC)c3)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F08 compound treatment 332.9 147.0 0.77 337.8 150.0 0.78 1.0928 1.0 1974956 ChemDiv1_010326 O=C/1N(C2CCCCC2)C(=S)S\C1=C/c3c(NCc4ccco4)nc5ccccn5c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F09 compound treatment 275.0 89.1 0.46 292.6 105.0 0.54 0.7131 0.9969 1138859 ChemDiv1_010327 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(CC=C)c3n2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F10 compound treatment 275.8 89.9 0.47 288.7 101.0 0.52 0.7017 0.9985 1516706 ChemDiv1_010328 OC1(CC(=O)c2ccco2)C(=O)N(Cc3ccccc3Cl)c4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F11 compound treatment 278.4 92.5 0.48 291.5 104.0 0.54 0.7216 0.9985 1974957 ChemDiv1_010329 CN(C)c1nc(OCCOC(=O)Nc2sc(NS(=O)(=O)c3ccc(C)cc3)nc2C)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F12 compound treatment 281.3 95.4 0.5 294.6 107.0 0.55 0.7437 0.9985 1974958 ChemDiv1_010330 COc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(C)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F13 compound treatment 273.6 87.7 0.46 287.3 99.3 0.52 0.6884 0.9982 1974959 ChemDiv1_010331 CN(Cc1ccccc1)C(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F14 compound treatment 274.4 88.5 0.46 286.8 98.8 0.51 0.6895 0.9986 1974960 ChemDiv1_010332 [O-][N+](=O)c1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F15 compound treatment 278.4 92.5 0.48 294.0 106.0 0.55 0.7308 0.9978 1974961 ChemDiv1_010333 CCOc1ccc2nc(NC3=NC(CC(=O)N3)c4ccc(OC)cc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F16 compound treatment 272.0 86.1 0.45 290.0 102.0 0.53 0.6925 0.9966 1974962 ChemDiv1_010334 O=C(NCCN1CCN(CC1)S(=O)(=O)c2ccccc2)C(=O)Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F17 compound treatment 275.8 89.9 0.47 290.3 102.0 0.53 0.7076 0.998 1974963 ChemDiv1_010335 COc1cc(/C=C/2\C(=NN(C2=O)c3cccc(Br)c3)C)ccc1OC(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F18 compound treatment 274.1 88.2 0.46 284.6 96.6 0.5 0.6804 0.999 1974964 ChemDiv1_010336 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F19 compound treatment 276.3 90.4 0.47 284.1 96.1 0.5 0.6866 0.9996 1974965 ChemDiv1_010337 C/N=C/1\SC(CC(=O)N)C(=O)N1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F20 compound treatment 278.6 92.7 0.48 283.5 95.5 0.5 0.6929 0.9999 1293977 ChemDiv1_010338 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cc(F)ccc2F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F21 compound treatment 271.5 85.6 0.45 281.3 93.3 0.49 0.6586 0.9991 1974966 ChemDiv1_010339 O=C1CSC(N1Cc2ccco2)c3cn(nc3c4cc5ccccc5oc4=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F22 compound treatment 275.8 89.9 0.47 282.8 94.8 0.49 0.68 0.9997 1974967 ChemDiv1_010340 CC(C)c1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F23 mock treatment 278.2 92.3 0.48 281.6 93.6 0.49 0.6845 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 F24 mock treatment 79.4 -107.0 -0.56 78.6 -109.0 -0.57 -0.795 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G01 compound treatment 283.7 97.8 0.51 289.8 102.0 0.53 0.7349 0.9998 1929269 ChemDiv1_010341 Clc1ccc(OCCCC(=O)Nc2nnc[nH]2)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G02 compound treatment 283.7 97.8 0.51 290.4 102.0 0.53 0.7371 0.9998 1974968 ChemDiv1_010342 CN/1C(=O)CC(S\C1=N/c2ccc(Br)cc2)C(=O)Nc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G03 compound treatment 283.6 97.7 0.51 288.2 100.0 0.52 0.7286 0.9999 1724662 ChemDiv1_010343 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G04 compound treatment 279.1 93.2 0.49 289.3 101.0 0.53 0.7161 0.9992 1974969 ChemDiv1_010344 COc1cccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccc(Br)cc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G05 compound treatment 315.7 130.0 0.68 324.5 137.0 0.71 0.9805 0.9997 1443677 ChemDiv1_010345 COC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccccc4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G06 compound treatment 276.6 90.7 0.47 291.0 103.0 0.54 0.7131 0.9981 1974970 ChemDiv1_010346 CCCOc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(OC)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G07 compound treatment 282.1 96.2 0.5 296.6 109.0 0.56 0.754 0.9983 1444843 ChemDiv1_010347 CC(C)(C)c1ccc(cc1)c2nc(NCc3cccnc3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G08 compound treatment 280.1 94.2 0.49 291.7 104.0 0.54 0.7286 0.9989 1406003 ChemDiv1_010348 COc1ccc(cc1)C(=O)COC(=O)c2ccc3OCCOc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G09 compound treatment 281.4 95.5 0.5 293.3 105.0 0.55 0.7393 0.9989 1974971 ChemDiv1_010349 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N3CCCc4ccccc34)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G10 compound treatment 277.0 91.1 0.48 289.2 101.0 0.53 0.708 0.9987 1974972 ChemDiv1_010350 COc1ccc(cc1)c2noc(CCCOc3ccc(Cl)cc3Cl)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G11 compound treatment 278.0 92.1 0.48 291.5 104.0 0.54 0.7201 0.9984 1974973 ChemDiv1_010351 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)Nc3nnc(CC(C)C)s3)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G12 compound treatment 274.9 89.0 0.46 288.3 100.0 0.52 0.6969 0.9983 1610297 ChemDiv1_010352 Brc1ccc(OCCn2c(NC(=O)c3cccs3)nc4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G13 compound treatment 276.1 90.2 0.47 295.3 107.0 0.56 0.7271 0.9964 1974974 ChemDiv1_010353 Cc1cccc(Oc2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G14 compound treatment 277.0 91.1 0.48 294.5 107.0 0.55 0.7274 0.9971 1191812 ChemDiv1_010354 Fc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G15 compound treatment 273.9 88.0 0.46 290.4 102.0 0.53 0.7009 0.9973 1974975 ChemDiv1_010355 Oc1ccc(Br)cc1c2nc(Cl)c3ccccc3n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G16 compound treatment 279.3 93.4 0.49 293.1 105.0 0.55 0.7308 0.9984 1974976 ChemDiv1_010356 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G17 compound treatment 277.8 91.9 0.48 289.5 102.0 0.53 0.712 0.9988 1974977 ChemDiv1_010357 COC(=O)CSc1nnc(c2ccncc2)n1Cc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G18 compound treatment 289.8 104.0 0.54 296.9 109.0 0.57 0.7835 0.9998 1974978 ChemDiv1_010358 CCOC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G19 compound treatment 278.1 92.2 0.48 285.5 97.5 0.51 0.6984 0.9996 1974979 ChemDiv1_010359 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(Br)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G20 compound treatment 276.6 90.7 0.47 284.8 96.8 0.5 0.6903 0.9995 1974980 ChemDiv1_010360 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3cc(Br)c(O)c(OC)c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G21 compound treatment 275.5 89.6 0.47 285.4 97.4 0.51 0.6885 0.9992 1974981 ChemDiv1_010361 CCN/1C(=O)CC(S\C1=N/c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G22 compound treatment 274.8 88.9 0.46 276.8 88.8 0.46 0.6543 1.0 1425199 ChemDiv1_010362 CCOC(=O)c1c(CSc2cccs2)n(C)c3cc(Br)c(O)c(CN(C)C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G23 mock treatment 277.8 91.9 0.48 280.9 92.9 0.48 0.6804 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 G24 mock treatment 78.9 -107.0 -0.56 79.7 -108.0 -0.56 -0.7928 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H01 compound treatment 278.6 92.7 0.48 288.7 101.0 0.52 0.712 0.9992 1974982 ChemDiv1_010363 Cc1ccc(CSCCNC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H02 compound treatment 282.0 96.1 0.5 287.2 99.2 0.52 0.7191 0.9999 1325231 ChemDiv1_010364 CC(=O)Oc1ccc(cc1)C2Nc3c(cc(Cl)cc3C4C=CCC42)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H03 compound treatment 277.8 91.9 0.48 289.8 102.0 0.53 0.7131 0.9988 1974983 ChemDiv1_010365 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H04 compound treatment 276.4 90.5 0.47 291.4 103.0 0.54 0.7138 0.9979 1368873 ChemDiv1_010366 O=C(Nc1ccc(Cc2ccncc2)cc1)C3CCC(CC3)N4C(=O)C5CC=CCC5C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H05 compound treatment 278.0 92.1 0.48 288.8 101.0 0.52 0.7102 0.999 1297550 ChemDiv1_010367 CC(C)OC(=O)C1=C(C)NC2=C(C1c3cc(Br)ccc3F)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H06 compound treatment 353.6 168.0 0.87 358.0 170.0 0.88 1.2434 1.0 1974984 ChemDiv1_010368 OCCNc1nc2ccccn2c(=O)c1/C=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H07 compound treatment 276.5 90.6 0.47 292.2 104.0 0.54 0.7171 0.9977 1673185 ChemDiv1_010369 COc1ccccc1C2CC(=O)C3=C(C2)NC(=C(C3c4cc(OC)c(OC)c(OC)c4)C(=O)OC5CCCC5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H08 compound treatment 281.0 95.1 0.5 297.4 109.0 0.57 0.7529 0.9977 1974985 ChemDiv1_010370 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)/C=C/c3ccccc3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H09 compound treatment 276.1 90.2 0.47 294.8 107.0 0.56 0.7252 0.9966 1620713 ChemDiv1_010371 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc(C)c(=O)[nH]2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H10 compound treatment 277.1 91.2 0.48 292.9 105.0 0.55 0.7219 0.9977 1594583 ChemDiv1_010372 OC1(CC(=O)c2cccs2)C(=O)N(Cc3ccccc3Cl)c4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H11 compound treatment 276.7 90.8 0.47 290.1 102.0 0.53 0.7102 0.9984 1473648 ChemDiv1_010373 CN(C)c1nc(Oc2ccc(OCc3ccccc3)nn2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H12 compound treatment 291.0 105.0 0.55 298.5 111.0 0.57 0.7938 0.9997 1974986 ChemDiv1_010374 Cc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H13 compound treatment 274.2 88.3 0.46 289.7 102.0 0.53 0.6995 0.9976 1974987 ChemDiv1_010375 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCCc2ccc(OC)c(OC)c2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H14 compound treatment 265.6 79.7 0.42 281.8 93.8 0.49 0.6387 0.9968 1974988 ChemDiv1_010376 Clc1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H15 compound treatment 276.7 90.8 0.47 288.7 101.0 0.52 0.705 0.9987 1311873 ChemDiv1_010377 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4ccc(OC)cc4)nc(C)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H16 compound treatment 278.1 92.2 0.48 285.2 97.2 0.51 0.6973 0.9997 1974989 ChemDiv1_010378 CCc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H17 compound treatment 276.9 91.0 0.47 292.1 104.0 0.54 0.7183 0.9979 1974990 ChemDiv1_010379 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)C(=O)O)C)ccc1OC(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H18 compound treatment 276.7 90.8 0.47 287.1 99.1 0.52 0.6991 0.9991 1974991 ChemDiv1_010380 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(C)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H19 compound treatment 276.7 90.8 0.47 284.6 96.6 0.5 0.6899 0.9996 1974992 ChemDiv1_010381 CCCCNC(=O)CC1S/C(=N\C)/N(C)C1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H20 compound treatment 276.5 90.6 0.47 282.4 94.4 0.49 0.6811 0.9998 1974993 ChemDiv1_010382 O=C(N/C(=C\c1ccco1)/C(=O)N2CCN(C/C=C/c3ccccc3)CC2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H21 compound treatment 274.3 88.4 0.46 280.0 92.0 0.48 0.6642 0.9998 1874291 ChemDiv1_010383 O=C1CSC(N1CC2CCCO2)c3cn(nc3c4cc5ccccc5oc4=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H22 compound treatment 278.8 92.9 0.48 283.3 95.3 0.5 0.6929 0.9999 1585715 ChemDiv1_010384 CCCc1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H23 mock treatment 273.4 87.5 0.46 282.3 94.3 0.49 0.6693 0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 H24 mock treatment 83.3 -103.0 -0.54 82.6 -105.0 -0.55 -0.7659 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I01 compound treatment 279.5 93.6 0.49 290.8 103.0 0.53 0.7231 0.999 3116459 ChemDiv1_010385 COc1ccc(Oc2coc3c(CN4CCCCCC4)c(O)ccc3c2=O)cc1.C1CCCNCC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I02 compound treatment 281.9 96.0 0.5 287.4 99.4 0.52 0.7194 0.9999 1974994 ChemDiv1_010386 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(Cl)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I03 compound treatment 278.9 93.0 0.48 292.9 105.0 0.55 0.7286 0.9983 1184886 ChemDiv1_010387 COc1ccc(cc1OC)C(=O)Oc2ccc3c(=O)c(Oc4cccc(C)c4)coc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I04 compound treatment 280.3 94.4 0.49 288.7 101.0 0.52 0.7183 0.9995 1974995 ChemDiv1_010388 CN/1C(=O)CC(S\C1=N/c2cccc(F)c2)C(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I05 compound treatment 281.2 95.3 0.5 290.6 103.0 0.53 0.7286 0.9994 1974996 ChemDiv1_010389 CN1CCN(Cc2c(O)ccc3c(=O)c(c4cccc(Cl)c4)c(oc23)C(F)(F)F)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I06 compound treatment 280.2 94.3 0.49 290.1 102.0 0.53 0.7231 0.9993 1974997 ChemDiv1_010390 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc4OCOc4c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I07 compound treatment 279.1 93.2 0.49 286.2 98.2 0.51 0.7047 0.9997 1974998 ChemDiv1_010391 COCCNc1nc(nc2ccccc12)c3ccc(cc3)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I08 compound treatment 275.9 90.0 0.47 290.9 103.0 0.53 0.7102 0.9979 1330195 ChemDiv1_010392 CC(=O)Oc1ccc(C2Nc3c(cc(Cl)cc3C4C=CCC42)C(=O)c5ccccc5)c(OC(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I09 compound treatment 271.7 85.8 0.45 280.3 92.3 0.48 0.6557 0.9994 1974999 ChemDiv1_010393 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(CCC#N)c3ccccc3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I10 compound treatment 278.4 92.5 0.48 291.3 103.0 0.54 0.7208 0.9986 1975000 ChemDiv1_010394 [O-][N+](=O)c1cccc(c1)c2noc(CCCOc3ccc(Cl)cc3Cl)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I11 compound treatment 274.8 88.9 0.46 284.5 96.5 0.5 0.6826 0.9992 1975001 ChemDiv1_010395 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(CCO)Cc3ccccc3)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I12 compound treatment 275.6 89.7 0.47 293.8 106.0 0.55 0.7197 0.9967 1975002 ChemDiv1_010396 Cc1cccc(OCCn2c(NC(=O)c3cccc(c3)[N+](=O)[O-])nc4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I13 compound treatment 277.1 91.2 0.48 286.7 98.7 0.51 0.6991 0.9993 1975003 ChemDiv1_010397 CCCCc1nnc(SCC(=O)Nc2ccc(Br)cn2)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I14 compound treatment 279.4 93.5 0.49 288.8 101.0 0.52 0.7153 0.9993 1473652 ChemDiv1_010398 Fc1ccccc1C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I15 compound treatment 275.8 89.9 0.47 288.9 101.0 0.52 0.7024 0.9984 1975004 ChemDiv1_010399 CCCN1C(=O)/C(=C\c2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])/c5ccccc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I16 compound treatment 280.0 94.1 0.49 294.4 106.0 0.55 0.7381 0.9982 1975005 ChemDiv1_010400 CCOC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I17 compound treatment 273.6 87.7 0.46 285.6 97.6 0.51 0.6822 0.9987 1233201 ChemDiv1_010401 COc1ccc2n(cc(CCN3C(=O)c4ccccc4C3=O)c2c1)C(=O)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I18 compound treatment 289.5 104.0 0.54 297.3 109.0 0.57 0.7838 0.9997 1975006 ChemDiv1_010402 CCCOC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I19 compound treatment 276.9 91.0 0.47 280.4 92.4 0.48 0.6752 1.0 1975007 ChemDiv1_010403 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(Cl)c(Cl)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I20 compound treatment 278.3 92.4 0.48 285.2 97.2 0.51 0.6981 0.9997 1975008 ChemDiv1_010404 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(O)c(OCC)c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I21 compound treatment 275.7 89.8 0.47 280.2 92.2 0.48 0.6701 0.9999 1975009 ChemDiv1_010405 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(OC)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I22 compound treatment 275.1 89.2 0.47 278.3 90.3 0.47 0.6609 1.0 1405149 ChemDiv1_010406 CCOC(=O)c1c(CSc2ccc(Cl)cc2)oc3ccc(O)c(CN(C)C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I23 mock treatment 276.5 90.6 0.47 278.7 90.7 0.47 0.6675 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 I24 mock treatment 80.5 -105.0 -0.55 82.5 -105.0 -0.55 -0.7766 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J01 compound treatment 281.1 95.2 0.5 291.1 103.0 0.54 0.7301 0.9993 1975010 ChemDiv1_010407 COc1ccc(CCNC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J02 compound treatment 277.5 91.6 0.48 282.7 94.7 0.49 0.6859 0.9999 1975011 ChemDiv1_010408 CC(=O)Oc1ccc(cc1)C2Nc3c(ccc([N+](=O)[O-])c3C4C=CCC42)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J03 compound treatment 282.6 96.7 0.5 286.4 98.4 0.51 0.7183 1.0 1975012 ChemDiv1_010409 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2cccc(c2)C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J04 compound treatment 274.9 89.0 0.46 294.1 106.0 0.55 0.7182 0.9963 1975013 ChemDiv1_010410 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)O)ccc1Oc4nc(Cl)ncc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J05 compound treatment 279.2 93.3 0.49 292.8 105.0 0.54 0.7293 0.9984 1364207 ChemDiv1_010411 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cc(Br)ccc4F)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J06 compound treatment 415.4 229.0 1.2 406.3 218.0 1.13 1.6489 0.9996 1975014 ChemDiv1_010412 CCCCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J07 compound treatment 279.3 93.4 0.49 292.8 105.0 0.54 0.7297 0.9984 1975015 ChemDiv1_010413 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)ccc3F)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J08 compound treatment 276.2 90.3 0.47 292.9 105.0 0.55 0.7186 0.9973 1548307 ChemDiv1_010414 COc1cc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4o3)cc2)nc(OC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J09 compound treatment 276.7 90.8 0.47 292.5 105.0 0.54 0.719 0.9976 1363863 ChemDiv1_010415 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nc3ccccc3o2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J10 compound treatment 279.1 93.2 0.49 292.8 105.0 0.54 0.7289 0.9984 1629327 ChemDiv1_010416 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccc(Cl)cc4)c5ccccc51 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J11 compound treatment 276.3 90.4 0.47 291.5 104.0 0.54 0.7138 0.9978 1975016 ChemDiv1_010417 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCCSCc2ccc(C)cc2)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J12 compound treatment 297.3 111.0 0.58 305.2 117.0 0.61 0.8416 0.9997 1646344 ChemDiv1_010418 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC35C(=O)Nc6ccccc65 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J13 compound treatment 276.6 90.7 0.47 293.6 106.0 0.55 0.7227 0.9972 1975017 ChemDiv1_010419 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J14 compound treatment 282.2 96.3 0.5 292.5 105.0 0.54 0.7393 0.9992 1975018 ChemDiv1_010420 Cc1ccc(CNC(=O)c2ccc3NC(C4CC=CC4c3c2)c5ccc(cc5)[N+](=O)[O-])cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J15 compound treatment 277.9 92.0 0.48 287.7 99.7 0.52 0.7058 0.9993 1975019 ChemDiv1_010421 Cc1cc(C)n(n1)C(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J16 compound treatment 276.2 90.3 0.47 286.1 98.1 0.51 0.6936 0.9992 1975020 ChemDiv1_010422 Brc1ccc(cc1)C(=O)N2CCN(CCNC(=O)C(=O)NCc3ccco3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J17 compound treatment 272.6 86.7 0.45 290.8 103.0 0.53 0.6976 0.9965 1975021 ChemDiv1_010423 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)ccc1OC(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J18 compound treatment 277.6 91.7 0.48 285.6 97.6 0.51 0.6969 0.9996 1975022 ChemDiv1_010424 Cc1ccc(cc1)C(=O)N2CCN(CCNC(=O)C(=O)NCc3ccccc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J19 compound treatment 273.9 88.0 0.46 281.9 93.9 0.49 0.6697 0.9995 1975023 ChemDiv1_010425 COc1ccccc1NC(=O)CC2S/C(=N\C)/N(C)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J20 compound treatment 270.3 84.4 0.44 280.7 92.7 0.48 0.652 0.999 1975024 ChemDiv1_010426 Cc1nc(SCC(=O)Nc2cccc(c2)C(=O)O)c(C#N)c(C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J21 compound treatment 278.5 92.6 0.48 282.3 94.3 0.49 0.6881 1.0 1312709 ChemDiv1_010427 O=C1CSC(N1Cc2cccnc2)c3cn(nc3c4cc5ccccc5oc4=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J22 compound treatment 276.2 90.3 0.47 280.9 92.9 0.48 0.6745 0.9999 1975025 ChemDiv1_010428 O=C(NCCc1c[nH]c2ccccc12)/C(=C/c3cccs3)/NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J23 mock treatment 277.4 91.5 0.48 285.0 97.0 0.5 0.694 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 J24 mock treatment 80.6 -105.0 -0.55 77.9 -110.0 -0.57 -0.7931 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K01 compound treatment 282.3 96.4 0.5 289.6 102.0 0.53 0.729 0.9997 1368628 ChemDiv1_010429 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K02 compound treatment 284.8 98.9 0.52 293.1 105.0 0.55 0.7511 0.9996 1975026 ChemDiv1_010430 COC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K03 compound treatment 285.2 99.3 0.52 289.8 102.0 0.53 0.7404 0.9999 1486358 ChemDiv1_010431 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3c(=O)c(Oc4cccc(C)c4)coc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K04 compound treatment 277.4 91.5 0.48 285.6 97.6 0.51 0.6962 0.9995 1975027 ChemDiv1_010432 CCOc1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccc(Br)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K05 compound treatment 281.5 95.6 0.5 289.1 101.0 0.53 0.7242 0.9996 1975028 ChemDiv1_010433 Oc1ccc2c(=O)c(c3cccc(Cl)c3)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K06 compound treatment 284.8 98.9 0.52 293.6 106.0 0.55 0.7529 0.9995 1975029 ChemDiv1_010434 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3cccc(F)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K07 compound treatment 275.0 89.1 0.46 289.4 101.0 0.53 0.7013 0.998 1975030 ChemDiv1_010435 COCCCNc1nc(nc2ccccc12)c3ccc(cc3)C(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K08 compound treatment 278.4 92.5 0.48 291.2 103.0 0.54 0.7205 0.9986 1669342 ChemDiv1_010436 Clc1ccc(C2Nc3c(cccc3C4C=CCC42)C(=O)N5CCOCC5)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K09 compound treatment 274.2 88.3 0.46 290.6 103.0 0.53 0.7028 0.9973 1975031 ChemDiv1_010437 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(c3)C(F)(F)F)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K10 compound treatment 274.8 88.9 0.46 293.5 106.0 0.55 0.7157 0.9965 1486772 ChemDiv1_010438 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K11 compound treatment 425.6 240.0 1.25 434.2 246.0 1.28 1.7891 0.9999 1975032 ChemDiv1_010439 OC(=O)CC(N1C(=O)/C(=C/c2ccc(o2)c3ccc(Br)cc3)/SC1=S)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K12 compound treatment 273.5 87.6 0.46 290.9 103.0 0.53 0.7013 0.9969 1975033 ChemDiv1_010440 Cc1cccc(OCCn2c(NC(=O)c3ccc(cc3)[N+](=O)[O-])nc4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K13 compound treatment 270.2 84.3 0.44 288.5 101.0 0.52 0.6803 0.9963 1975034 ChemDiv1_010441 CCCCc1nnc(SCC(=O)NC2CCCCC2)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K14 compound treatment 271.0 85.1 0.44 288.4 100.0 0.52 0.6829 0.9967 1417307 ChemDiv1_010442 Cc1ccc(OCCn2c(NC(=O)c3ccco3)nc4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K15 compound treatment 275.0 89.1 0.46 287.1 99.1 0.52 0.6929 0.9987 1975035 ChemDiv1_010443 COc1ccc(cc1)n2c(/C=C\3/C(=O)N(C)c4ccc(Br)cc34)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K16 compound treatment 291.0 105.0 0.55 303.3 115.0 0.6 0.8114 0.999 1975036 ChemDiv1_010444 COC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K17 compound treatment 278.4 92.5 0.48 286.2 98.2 0.51 0.7021 0.9996 1243779 ChemDiv1_010445 Clc1ccc(cc1)C(=O)NCCc2c[nH]c3ccc(OCc4ccccc4)cc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K18 compound treatment 273.9 88.0 0.46 285.4 97.4 0.51 0.6826 0.9988 1975037 ChemDiv1_010446 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(cc3)N(C)C)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K19 compound treatment 278.2 92.3 0.48 282.5 94.5 0.49 0.6878 0.9999 1975038 ChemDiv1_010447 CCN/1C(=O)CC(S\C1=N/c2ccc(cc2)C(=O)OC)C(=O)Nc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K20 compound treatment 278.2 92.3 0.48 284.7 96.7 0.5 0.6958 0.9998 1723367 ChemDiv1_010448 CCOC(=O)c1c(CN(C)c2ccccc2)oc3cc(Br)c(O)c(CN(C)C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K21 compound treatment 274.7 88.8 0.46 281.5 93.5 0.49 0.6712 0.9997 1975039 ChemDiv1_010449 CCOc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K22 compound treatment 272.9 87.0 0.45 278.0 90.0 0.47 0.6517 0.9999 1474146 ChemDiv1_010450 CCOC(=O)c1c(CSc2ccc(CC)cc2)oc3ccc(O)c(CN(C)C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K23 mock treatment 279.1 93.2 0.49 278.8 90.8 0.47 0.6775 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 K24 mock treatment 83.8 -102.0 -0.53 77.1 -111.0 -0.58 -0.7843 -0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L01 compound treatment 286.3 100.0 0.52 289.5 102.0 0.53 0.7434 1.0 1975040 ChemDiv1_010451 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L02 compound treatment 267.1 81.2 0.42 275.4 87.4 0.45 0.6207 0.9994 1427968 ChemDiv1_010452 CC(=O)Oc1ccc(C2Nc3ccc(cc3C4C=CCC42)C(=O)O)c(OC(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L03 compound treatment 277.3 91.4 0.48 288.8 101.0 0.52 0.7076 0.9989 1975041 ChemDiv1_010453 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)c3ccc(OC)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L04 compound treatment 276.5 90.6 0.47 286.2 98.2 0.51 0.6951 0.9992 1571986 ChemDiv1_010454 Clc1ccc(cc1NC(=O)COc2ccc(Br)cc2)c3nc4ncccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L05 compound treatment 276.2 90.3 0.47 286.7 98.7 0.51 0.6958 0.9991 1871399 ChemDiv1_010455 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L06 compound treatment 363.7 178.0 0.93 363.4 175.0 0.91 1.3005 1.0 1975042 ChemDiv1_010456 CC1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C\4/SC(=S)N(C5CCCCC5)C4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L07 compound treatment 278.2 92.3 0.48 290.0 102.0 0.53 0.7153 0.9988 1168489 ChemDiv1_010457 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccc(C)cc5c4=O)C(=O)OC6CCCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L08 compound treatment 280.2 94.3 0.49 292.2 104.0 0.54 0.7308 0.9988 1932340 ChemDiv1_010458 CN(C)c1nc(nc(n1)N2CC(=O)N(C2=N)c3ccccc3)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L09 compound treatment 276.9 91.0 0.47 291.6 104.0 0.54 0.7164 0.998 1174931 ChemDiv1_010459 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nc3ccccc3[nH]2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L10 compound treatment 276.2 90.3 0.47 290.9 103.0 0.53 0.7113 0.998 1432485 ChemDiv1_010460 OC1(CC(=O)c2ccco2)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L11 compound treatment 281.0 95.1 0.5 288.4 100.0 0.52 0.7198 0.9997 1975043 ChemDiv1_010461 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L12 compound treatment 286.0 100.0 0.52 292.7 105.0 0.54 0.754 0.9998 1124003 ChemDiv1_010462 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC35C(=O)N(CC=C)c6ccccc65 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L13 compound treatment 275.5 89.6 0.47 283.6 95.6 0.5 0.6818 0.9995 1975044 ChemDiv1_010463 COc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCN(CC2)c3ccccc3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L14 compound treatment 278.7 92.8 0.48 286.0 98.0 0.51 0.7025 0.9997 1975045 ChemDiv1_010464 CCOC(=O)c1sc(NC(=O)CSc2nnc(CC)[nH]2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L15 compound treatment 276.2 90.3 0.47 286.3 98.3 0.51 0.6944 0.9992 1975046 ChemDiv1_010465 FC(F)(F)c1cc(NC(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O)ccc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L16 compound treatment 278.6 92.7 0.48 284.9 96.9 0.5 0.6981 0.9998 1975047 ChemDiv1_010466 COc1ccc(cc1)C(=O)N2CCN(CCNC(=O)C(=O)Nc3ccc(C)cc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L17 compound treatment 274.8 88.9 0.46 288.2 100.0 0.52 0.6962 0.9983 1975048 ChemDiv1_010467 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)ccc1OC(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L18 compound treatment 276.2 90.3 0.47 287.3 99.3 0.52 0.698 0.9989 1500804 ChemDiv1_010468 CN(C)c1ccc(cc1)C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L19 compound treatment 275.2 89.3 0.47 281.9 93.9 0.49 0.6745 0.9997 1975049 ChemDiv1_010469 CCOC(=O)c1ccc(NC(=O)CC2S/C(=N\C)/N(C)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L20 compound treatment 279.0 93.1 0.49 284.5 96.5 0.5 0.6981 0.9999 1975050 ChemDiv1_010470 CC(C)Cc1ccc(C#N)c(SCc2nnc(o2)c3ccccc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L21 compound treatment 277.7 91.8 0.48 282.9 94.9 0.49 0.6874 0.9999 1975051 ChemDiv1_010471 O=C1CSC(N1CC2COc3ccccc3O2)c4cn(nc4c5cc6ccccc6oc5=O)c7ccccc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L22 compound treatment 276.5 90.6 0.47 279.3 91.3 0.47 0.6697 1.0 1871345 ChemDiv1_010472 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L23 mock treatment 277.4 91.5 0.48 277.1 89.1 0.46 0.665 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 L24 mock treatment 78.0 -108.0 -0.56 80.7 -107.0 -0.56 -0.7924 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M01 compound treatment 280.6 94.7 0.49 285.8 97.8 0.51 0.7087 0.9999 1141931 ChemDiv1_010473 Clc1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M02 compound treatment 279.6 93.7 0.49 287.0 99.0 0.51 0.7095 0.9997 1975052 ChemDiv1_010474 COc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)Nc4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M03 compound treatment 281.3 95.4 0.5 283.7 95.7 0.5 0.7036 1.0 1324517 ChemDiv1_010475 CCCNC(=O)Nc1nc(CC(=O)OCC)cs1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M04 compound treatment 278.9 93.0 0.48 289.5 102.0 0.53 0.7161 0.9991 1975053 ChemDiv1_010476 CCN/1C(=O)CC(S\C1=N/c2cccc(F)c2)C(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M05 compound treatment 279.1 93.2 0.49 288.1 100.0 0.52 0.7117 0.9994 1975054 ChemDiv1_010477 COc1ccc(Oc2c(oc3c(CN4CCCCC4C)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M06 compound treatment 280.2 94.3 0.49 290.1 102.0 0.53 0.7231 0.9993 1975055 ChemDiv1_010478 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccccc3OC)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M07 compound treatment 278.4 92.5 0.48 288.5 101.0 0.52 0.7106 0.9992 1672057 ChemDiv1_010479 CC(C)(C)c1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M08 compound treatment 279.4 93.5 0.49 291.6 104.0 0.54 0.7256 0.9988 1691574 ChemDiv1_010480 COC(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M09 compound treatment 279.4 93.5 0.49 290.4 102.0 0.53 0.7212 0.999 1975056 ChemDiv1_010481 CCN(CCO)C(=O)CCN1C(=O)/C(=C/c2cccs2)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M10 compound treatment 274.6 88.7 0.46 284.7 96.7 0.5 0.6826 0.9991 1661010 ChemDiv1_010482 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3(CCCC3)c4ccccc4)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M11 compound treatment 279.0 93.1 0.49 289.5 102.0 0.53 0.7164 0.9991 1975057 ChemDiv1_010483 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(O)c(c3)C(=O)O)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M12 compound treatment 274.3 88.4 0.46 295.2 107.0 0.56 0.7201 0.9956 1603477 ChemDiv1_010484 Cc1ccc(OCCn2c(NC(=O)c3ccc(Cl)cc3)nc4ccccc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M13 compound treatment 280.2 94.3 0.49 293.4 105.0 0.55 0.7352 0.9985 1975058 ChemDiv1_010485 CCCCc1nnc(SCC(=O)Nc2cc(C)on2)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M14 compound treatment 275.7 89.8 0.47 285.0 97.0 0.5 0.6877 0.9993 1699901 ChemDiv1_010486 Cc1cccc(OCCn2c(NC(=O)c3ccco3)nc4ccccc24)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M15 compound treatment 277.6 91.7 0.48 289.3 101.0 0.53 0.7105 0.9988 1975059 ChemDiv1_010487 Cc1c(C)c2ccccc2n1C(=O)CSc3nnc(o3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M16 compound treatment 265.0 79.1 0.41 279.4 91.4 0.48 0.6277 0.9975 1975060 ChemDiv1_010488 NS(=O)(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M17 compound treatment 275.4 89.5 0.47 284.6 96.6 0.5 0.6852 0.9993 1975061 ChemDiv1_010489 C(CSSCCNCCc1c[nH]c2ccccc12)NCCc3c[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M18 compound treatment 277.1 91.2 0.48 286.0 98.0 0.51 0.6966 0.9994 1975062 ChemDiv1_010490 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc4OCOc4c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M19 compound treatment 275.7 89.8 0.47 280.8 92.8 0.48 0.6723 0.9999 1975063 ChemDiv1_010491 CCN/1C(=O)CC(S\C1=N/c2cccc(Cl)c2)C(=O)Nc3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M20 compound treatment 274.9 89.0 0.46 281.5 93.5 0.49 0.6719 0.9997 1975064 ChemDiv1_010492 CCOC(=O)c1c(oc2ccc(O)cc12)c3cc(Br)c(OC)c(Br)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M21 compound treatment 272.6 86.7 0.45 280.6 92.6 0.48 0.6601 0.9995 1975065 ChemDiv1_010493 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(F)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M22 compound treatment 278.1 92.2 0.48 277.6 89.6 0.47 0.6694 0.9999 1975066 ChemDiv1_010494 CC(=C)C(=O)OCCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M23 mock treatment 276.6 90.7 0.47 278.7 90.7 0.47 0.6679 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 M24 mock treatment 190.1 4.17 0.02 188.1 0.122 0.0 0.0158 0.7274 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N01 compound treatment 285.5 99.6 0.52 286.1 98.1 0.51 0.7279 1.0 1975067 ChemDiv1_010495 Cc1cccc(N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N02 compound treatment 285.2 99.3 0.52 289.3 101.0 0.53 0.7386 1.0 1247981 ChemDiv1_010496 CC(=O)Oc1ccc(C2Nc3ccc(C)cc3C4C=CCC42)c(OC(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N03 compound treatment 282.2 96.3 0.5 283.3 95.3 0.5 0.7055 1.0 1975068 ChemDiv1_010497 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)C(F)(F)F)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N04 compound treatment 279.4 93.5 0.49 288.2 100.0 0.52 0.7131 0.9995 1975069 ChemDiv1_010498 CCCCOc1cccc(c1)C(=O)Nc2cc(ccc2Cl)c3nc4ncccc4o3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N05 compound treatment 278.8 92.9 0.48 285.0 97.0 0.5 0.6992 0.9998 1975070 ChemDiv1_010499 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N06 compound treatment 391.7 206.0 1.07 399.5 212.0 1.1 1.5365 0.9999 1975071 ChemDiv1_010500 CC(N1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(C)CC4)/SC1=S)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N07 compound treatment 278.1 92.2 0.48 285.2 97.2 0.51 0.6973 0.9997 1410739 ChemDiv1_010501 Clc1ccc2nc(NCCN3CCOCC3)nc(c4ccccc4)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N08 compound treatment 280.1 94.2 0.49 291.5 104.0 0.54 0.7278 0.999 1975072 ChemDiv1_010502 CC(=O)c1cccc(c1)N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N09 compound treatment 275.6 89.7 0.47 288.0 100.0 0.52 0.6984 0.9986 1272241 ChemDiv1_010503 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nccn2C)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N10 compound treatment 280.8 94.9 0.49 285.0 97.0 0.5 0.7065 1.0 1118978 ChemDiv1_010504 OC1(CC(=O)c2cccs2)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N11 compound treatment 279.4 93.5 0.49 290.7 103.0 0.53 0.7223 0.999 1975073 ChemDiv1_010505 Cc1cccc(N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N12 compound treatment 306.0 120.0 0.63 311.5 124.0 0.64 0.8969 0.9999 1975074 ChemDiv1_010506 Brc1ccc2OC(N3N=C(CC3c2c1)c4ccco4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N13 compound treatment 278.3 92.4 0.48 285.6 97.6 0.51 0.6995 0.9997 1975075 ChemDiv1_010507 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N14 compound treatment 278.2 92.3 0.48 289.5 102.0 0.53 0.7135 0.9989 1260330 ChemDiv1_010508 C=CCn1c2ccccc2c3nnc(SCC(=O)Nc4nc5ccccc5s4)nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N15 compound treatment 276.2 90.3 0.47 284.3 96.3 0.5 0.687 0.9995 1975076 ChemDiv1_010509 O=C(C(Cc1ccccc1)N2C(=O)C3CCCCC3C2=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N16 compound treatment 277.2 91.3 0.48 286.4 98.4 0.51 0.6984 0.9994 1975077 ChemDiv1_010510 Fc1cccc(c1)C(=O)N2CCN(CCNC(=O)C(=O)Nc3ccccc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N17 compound treatment 277.8 91.9 0.48 289.3 101.0 0.53 0.7113 0.9989 1975078 ChemDiv1_010511 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccccc3Cl)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N18 compound treatment 276.1 90.2 0.47 284.0 96.0 0.5 0.6855 0.9996 1551699 ChemDiv1_010512 COc1ccc(C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N19 compound treatment 276.7 90.8 0.47 284.4 96.4 0.5 0.6892 0.9996 1975079 ChemDiv1_010513 CCOC(=O)c1ccccc1NC(=O)CC2S/C(=N\C)/N(C)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N20 compound treatment 283.6 97.7 0.51 280.7 92.7 0.48 0.7011 0.9996 1198296 ChemDiv1_010514 CCCCc1ccc2c(N)c(sc2n1)C(=O)Nc3ccc(cc3)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N21 compound treatment 273.6 87.7 0.46 280.0 92.0 0.48 0.6616 0.9997 1975080 ChemDiv1_010515 CC(=O)Oc1ccc(C2Nc3ccc(cc3C4C=CCC42)C(=O)C)c(OC(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N22 compound treatment 277.1 91.2 0.48 278.2 90.2 0.47 0.6679 1.0 1871355 ChemDiv1_010516 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccc(c4)[N+](=O)[O-])C(=O)OCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N23 mock treatment 275.2 89.3 0.47 284.5 96.5 0.5 0.684 0.9993 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 N24 mock treatment 185.9 -0.0344 0.0 194.8 6.82 0.04 0.0249 0.7035 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O01 compound treatment 288.2 102.0 0.53 292.9 105.0 0.55 0.7629 0.9999 1233473 ChemDiv1_010517 Clc1ccc(cc1)c2nc(NCc3ccco3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O02 compound treatment 281.0 95.1 0.5 287.5 99.5 0.52 0.7165 0.9998 1975081 ChemDiv1_010518 CCN/1C(=O)CC(S\C1=N/c2ccc3OCOc3c2)C(=O)Nc4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O03 compound treatment 281.1 95.2 0.5 282.5 94.5 0.49 0.6985 1.0 1331525 ChemDiv1_010519 CC(C)c1nnc(NC(=O)CCN2C(=O)c3ccccc3C2=O)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O04 compound treatment 284.3 98.4 0.51 286.0 98.0 0.51 0.7231 1.0 1975082 ChemDiv1_010520 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(C)c(C)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O05 compound treatment 277.5 91.6 0.48 285.2 97.2 0.51 0.6951 0.9996 1924256 ChemDiv1_010521 COc1ccc(Oc2c(oc3c(CN4CCCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O06 compound treatment 279.0 93.1 0.49 284.8 96.8 0.5 0.6992 0.9998 1975083 ChemDiv1_010522 CCN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O07 compound treatment 278.6 92.7 0.48 288.9 101.0 0.52 0.7128 0.9992 1975084 ChemDiv1_010523 CC(C)(C)c1ccc(cc1)c2nc(NCCCN3CCOCC3)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O08 compound treatment 277.3 91.4 0.48 290.4 102.0 0.53 0.7135 0.9985 1176027 ChemDiv1_010524 CCOc1ccc(cc1Br)C(=O)Nc2ccc3oc(nc3c2)c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O09 compound treatment 278.1 92.2 0.48 284.3 96.3 0.5 0.694 0.9998 1975085 ChemDiv1_010525 OCCN(Cc1ccccc1)C(=O)CCN2C(=O)/C(=C/c3cccs3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O10 compound treatment 281.2 95.3 0.5 285.7 97.7 0.51 0.7106 0.9999 1251763 ChemDiv1_010526 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc3nc(oc3c2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O11 compound treatment 282.0 96.1 0.5 289.3 101.0 0.53 0.7268 0.9997 1975086 ChemDiv1_010527 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(c3)C(=O)O)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O12 compound treatment 275.5 89.6 0.47 284.7 96.7 0.5 0.6859 0.9993 1975087 ChemDiv1_010528 [O-][N+](=O)c1cccc(c1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O13 compound treatment 278.2 92.3 0.48 286.8 98.8 0.51 0.7036 0.9995 1975088 ChemDiv1_010529 CC(C)Cc1nnc(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O14 compound treatment 276.6 90.7 0.47 286.6 98.6 0.51 0.6969 0.9992 1526256 ChemDiv1_010530 O=C(Nc1nc2ccccc2n1CCOc3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O15 compound treatment 275.7 89.8 0.47 284.9 96.9 0.5 0.6874 0.9993 1663697 ChemDiv1_010531 COC(=O)C1CCN(CC1)C(=O)c2cc(nc3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O16 compound treatment 283.8 97.9 0.51 295.3 107.0 0.56 0.7555 0.999 1975089 ChemDiv1_010532 NS(=O)(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc(cc4)S(=O)(=O)N)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O17 compound treatment 273.5 87.6 0.46 283.8 95.8 0.5 0.6752 0.9991 1176133 ChemDiv1_010533 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3[nH]cc(CCN4C(=O)c5ccccc5C4=O)c3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O18 compound treatment 259.9 74.0 0.39 277.1 89.1 0.46 0.6004 0.9959 1975090 ChemDiv1_010534 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3c[nH]c4ccccc34)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O19 compound treatment 274.9 89.0 0.46 282.7 94.7 0.49 0.6763 0.9996 1975091 ChemDiv1_010535 COc1ccc(NC(=O)C2CC(=O)N(CC=C)/C(=N/c3ccc(Cl)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O20 compound treatment 274.3 88.4 0.46 278.0 90.0 0.47 0.6568 1.0 1731326 ChemDiv1_010536 CCOC(=O)c1c(CSc2ccccn2)n(C)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O21 compound treatment 276.8 90.9 0.47 281.0 93.0 0.48 0.6771 1.0 1975092 ChemDiv1_010537 COC(=O)c1ccc(NC(=O)C2CC(=O)N(CC=C)/C(=N/c3ccc(Cl)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O22 compound treatment 277.9 92.0 0.48 275.5 87.5 0.45 0.6609 0.9996 1432108 ChemDiv1_010538 Cc1cc(C)c(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O23 mock treatment 279.3 93.4 0.49 280.1 92.1 0.48 0.683 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 O24 mock treatment 96.8 -89.1 -0.46 93.6 -94.4 -0.49 -0.6757 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P01 compound treatment 285.9 100.0 0.52 288.7 101.0 0.52 0.739 1.0 1975093 ChemDiv1_010539 COc1cccc(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P02 compound treatment 292.4 106.0 0.56 293.7 106.0 0.55 0.7813 1.0 1975094 ChemDiv1_010540 Clc1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)/C=C/c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P03 compound treatment 282.3 96.4 0.5 285.0 97.0 0.5 0.7121 1.0 1975095 ChemDiv1_010541 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)C(F)(F)F)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P04 compound treatment 282.4 96.5 0.5 287.6 99.6 0.52 0.722 0.9999 1624744 ChemDiv1_010542 O=S1(=O)C=C(Sc2nc3ccccc3o2)c4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P05 compound treatment 280.0 94.1 0.49 282.6 94.6 0.49 0.6948 1.0 1975096 ChemDiv1_010543 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)cc3)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P06 compound treatment 327.2 141.0 0.74 334.3 146.0 0.76 1.0589 0.9999 1975097 ChemDiv1_010544 COCCCN1C(=O)/C(=C\c2c(nc3c(C)cccn3c2=O)N4CC(C)OC(C)C4)/SC1=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P07 compound treatment 283.8 97.9 0.51 288.2 100.0 0.52 0.7294 0.9999 1603929 ChemDiv1_010545 COC(=O)Nc1nc2cc(Cl)c(Oc3ccc4ccccc4c3Cl)cc2[nH]1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P08 compound treatment 283.5 97.6 0.51 290.1 102.0 0.53 0.7352 0.9998 1484881 ChemDiv1_010546 OC1(CC(=O)c2cc3ccccc3oc2=O)C(=O)Nc4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P09 compound treatment 277.7 91.8 0.48 289.7 102.0 0.53 0.7124 0.9988 1233662 ChemDiv1_010547 CCOC(=O)c1sc(NC(=O)CSc2nnc(C)c(=O)[nH]2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P10 compound treatment 278.8 92.9 0.48 284.8 96.8 0.5 0.6984 0.9998 1234770 ChemDiv1_010548 COc1ccc(cc1OC)C(=O)CC2(O)C(=O)Nc3ccc(C)cc32 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P11 compound treatment 277.4 91.5 0.48 288.3 100.0 0.52 0.7061 0.999 1975098 ChemDiv1_010549 Cc1c(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P12 compound treatment 279.1 93.2 0.49 286.6 98.6 0.51 0.7061 0.9996 1460653 ChemDiv1_010550 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccc3C(=O)O)c4ccccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P13 compound treatment 274.9 89.0 0.46 284.7 96.7 0.5 0.6837 0.9992 1626245 ChemDiv1_010551 COc1ccc(cc1OC)c2noc(COc3ccc(Cl)cc3Cl)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P14 compound treatment 279.0 93.1 0.49 288.7 101.0 0.52 0.7135 0.9993 1788973 ChemDiv1_010552 CSc1nnc-2c(OC(Nc3ccccc32)c4ccc(cc4)[N+](=O)[O-])n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P15 compound treatment 277.2 91.3 0.48 286.9 98.9 0.51 0.7002 0.9993 1975099 ChemDiv1_010553 Cc1cc(C)nc(NC(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P16 compound treatment 278.3 92.4 0.48 286.0 98.0 0.51 0.701 0.9996 1975100 ChemDiv1_010554 CCc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc(C)cc3)CC2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P17 compound treatment 278.5 92.6 0.48 285.0 97.0 0.5 0.6981 0.9998 1975101 ChemDiv1_010555 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3cc(C)c(Cl)c(C)c3)coc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P18 compound treatment 278.8 92.9 0.48 281.6 93.6 0.49 0.6867 1.0 1401069 ChemDiv1_010556 CCCc1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P19 compound treatment 278.1 92.2 0.48 281.5 93.5 0.49 0.6837 1.0 1975102 ChemDiv1_010557 CCOC(=O)c1c(C)c(C)sc1NC(=O)CC2S/C(=N\C)/N(C)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P20 compound treatment 275.8 89.9 0.47 279.4 91.4 0.48 0.6675 1.0 1975103 ChemDiv1_010558 COc1ccc(cc1)c2cc(c(C#N)c(SCC(=O)Nc3cc(C)on3)n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P21 compound treatment 269.5 83.6 0.44 274.1 86.1 0.45 0.6248 0.9999 1445243 ChemDiv1_010559 CC(=O)Oc1ccc(C2Nc3c(cccc3C4C=CCC42)C(=O)O)c(OC(=O)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P22 compound treatment 279.1 93.2 0.49 282.1 94.1 0.49 0.6896 1.0 1871396 ChemDiv1_010560 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P23 mock treatment 276.1 90.2 0.47 283.2 95.2 0.49 0.6826 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.616 P24 mock treatment 85.2 -101.0 -0.53 91.5 -96.5 -0.5 -0.7262 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A01 compound treatment 282.3 95.4 0.5 290.4 102.0 0.53 0.7276 0.9995 1871199 ChemDiv1_010561 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccc(c4)[N+](=O)[O-])C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A02 compound treatment 280.3 93.4 0.49 286.8 98.6 0.51 0.7069 0.9997 1975104 ChemDiv1_010562 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3cccc(OCc4ccccc4)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A03 compound treatment 281.0 94.1 0.49 287.2 99.0 0.51 0.711 0.9997 1975105 ChemDiv1_010563 COc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A04 compound treatment 279.2 92.3 0.48 285.4 97.2 0.51 0.6977 0.9997 1975106 ChemDiv1_010564 NC1=C(C#N)C(c2ccc(Cl)c(c2)[N+](=O)[O-])c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A05 compound treatment 281.5 94.6 0.49 273.0 84.8 0.44 0.6606 0.9984 1871237 ChemDiv1_010565 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A06 compound treatment 280.8 93.9 0.49 288.8 101.0 0.52 0.7161 0.9995 1932635 ChemDiv1_010566 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)c(Cl)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A07 compound treatment 279.5 92.6 0.48 287.9 99.7 0.52 0.708 0.9994 1724137 ChemDiv1_010567 NC1=C(C#N)C(c2ccc(Br)s2)c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A08 compound treatment 277.0 90.1 0.47 282.5 94.3 0.49 0.679 0.9998 1285413 ChemDiv1_010568 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(Cl)cc4Cl)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A09 compound treatment 277.8 90.9 0.47 285.6 97.4 0.51 0.6933 0.9995 1975107 ChemDiv1_010569 Cc1cc(c(C#N)c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)n1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A10 compound treatment 277.0 90.1 0.47 287.8 99.6 0.52 0.6984 0.9989 1975108 ChemDiv1_010570 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3OC)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A11 compound treatment 276.0 89.1 0.47 283.9 95.7 0.5 0.6804 0.9994 1975109 ChemDiv1_010571 CC(=O)c1cc(C#N)c(SCC(=O)NC2(CC3CC4CC(C3)C2)C4)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A12 compound treatment 274.4 87.5 0.46 286.5 98.3 0.51 0.6841 0.9984 1292071 ChemDiv1_010572 CCOC(=O)C1=C(N)OC(=C(C(=O)OCC)C21C(=O)Nc3ccccc32)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A13 compound treatment 271.5 84.6 0.44 280.6 92.4 0.48 0.6517 0.9991 1975110 ChemDiv1_010573 COC(=O)C1=C(C)OC(=C(C#N)C1c2cc(cs2)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A14 compound treatment 262.6 75.7 0.4 270.4 82.2 0.43 0.5814 0.9992 1975111 ChemDiv1_010574 CC(C)N1C/C(=C\c2ccc(F)cc2)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A15 compound treatment 279.9 93.0 0.49 287.8 99.6 0.52 0.7091 0.9995 1975112 ChemDiv1_010575 Cc1csc(NC(=O)CSc2nc(cc(c3cccs3)c2C#N)c4cccs4)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A16 compound treatment 272.3 85.4 0.45 277.6 89.4 0.46 0.6436 0.9998 1975113 ChemDiv1_010576 CC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OCC=C)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A17 compound treatment 278.3 91.4 0.48 286.4 98.2 0.51 0.6981 0.9994 1975114 ChemDiv1_010577 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(F)c(Br)c2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A18 compound treatment 274.7 87.8 0.46 285.4 97.2 0.51 0.6811 0.9988 1975115 ChemDiv1_010578 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A19 compound treatment 280.3 93.4 0.49 285.5 97.3 0.51 0.7022 0.9998 1975116 ChemDiv1_010579 CCCCOC(=O)c1ccc(NCN2C(=O)S/C(=C\c3ccc(O)c(OC)c3)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A20 compound treatment 287.3 100.0 0.52 290.2 102.0 0.53 0.7453 1.0 1727219 ChemDiv1_010580 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3cccc(OCc4ccccc4)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A21 compound treatment 275.4 88.5 0.46 279.7 91.5 0.48 0.6628 0.9999 1975117 ChemDiv1_010581 [O-][N+](=O)c1cccc(NC(=O)CSc2nnc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])s2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A22 compound treatment 277.4 90.5 0.47 278.1 89.9 0.47 0.6643 1.0 1975118 ChemDiv1_010582 COc1ccc(Br)cc1C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A23 mock treatment 281.5 94.6 0.49 279.8 91.6 0.48 0.6856 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 A24 mock treatment 76.5 -110.0 -0.58 78.4 -110.0 -0.57 -0.8108 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B01 compound treatment 282.5 95.6 0.5 285.4 97.2 0.51 0.7099 1.0 1975119 ChemDiv1_010583 Cc1cccc(NC(=O)CSc2nc(N)c(C#N)c(c3cccs3)c2C#N)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B02 compound treatment 279.1 92.2 0.48 282.8 94.6 0.49 0.6878 0.9999 1975120 ChemDiv1_010584 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B03 compound treatment 279.6 92.7 0.48 283.4 95.2 0.49 0.6919 0.9999 1975121 ChemDiv1_010585 Nc1nc(SCC(=O)Nc2cccc(c2)[N+](=O)[O-])c(C#N)c(c1C#N)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B04 compound treatment 277.7 90.8 0.47 283.8 95.6 0.5 0.6863 0.9997 1324637 ChemDiv1_010586 CCc1cc2c(=O)n3CCc4c([nH]c5ccc(OC)cc45)-c3nc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B05 compound treatment 319.0 132.0 0.69 334.1 146.0 0.76 1.0236 0.9989 1975122 ChemDiv1_010587 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccccc4OC)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B06 compound treatment 276.9 90.0 0.47 286.1 97.9 0.51 0.6918 0.9992 1651242 ChemDiv1_010588 CC1=C(C)C2C3C(C1c4ccccc24)C(=O)N(Cc5ccc(Br)cc5)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B07 compound treatment 278.0 91.1 0.48 289.1 101.0 0.52 0.7069 0.9988 1975123 ChemDiv1_010589 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccs3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B08 compound treatment 275.8 88.9 0.46 283.8 95.6 0.5 0.6793 0.9994 1975124 ChemDiv1_010590 CC1=NN(C(=O)C1=CNc2c(Cl)cc(Cl)cc2Cl)c3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B09 compound treatment 278.1 91.2 0.48 288.9 101.0 0.52 0.7065 0.9989 1975125 ChemDiv1_010591 COc1cccc(/C=C/2\CCCC3=C2OC(=C(C#N)C3c4cccc(OC)c4)N)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B10 compound treatment 277.3 90.4 0.47 289.7 101.0 0.53 0.7065 0.9985 1710241 ChemDiv1_010592 CCOC(=O)c1c(C)n(C)c2cc(CN(C)C)c(O)c(c12)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B11 compound treatment 274.9 88.0 0.46 280.9 92.7 0.48 0.6653 0.9997 1573474 ChemDiv1_010593 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(CC)cc2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B12 compound treatment 271.2 84.3 0.44 283.8 95.6 0.5 0.6624 0.9982 1777954 ChemDiv1_010594 COc1cc(cc([N+](=O)[O-])c1O)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B13 compound treatment 276.0 89.1 0.47 287.3 99.1 0.51 0.6929 0.9987 1975126 ChemDiv1_010595 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(Cl)c(Cl)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B14 compound treatment 271.2 84.3 0.44 281.1 92.9 0.48 0.6524 0.9989 1975127 ChemDiv1_010596 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc5ccccc45)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B15 compound treatment 273.8 86.9 0.45 285.3 97.1 0.5 0.6775 0.9986 1555216 ChemDiv1_010597 Cc1c(Nc2nc3nonc3nc2Nc4ccc(C)c(C)c4)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B16 compound treatment 273.6 86.7 0.45 279.1 90.9 0.47 0.6539 0.9998 1975128 ChemDiv1_010598 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)C(=O)Nc5cccc6C(=O)c7ccccc7C(=O)c56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B17 compound treatment 276.1 89.2 0.47 281.3 93.1 0.48 0.6712 0.9998 1975129 ChemDiv1_010599 COC(=O)CN1C(=N)N(CC1=O)c2nc(nc(n2)N(C)C)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B18 compound treatment 276.8 89.9 0.47 283.3 95.1 0.49 0.6812 0.9997 1205571 ChemDiv1_010600 COC(=O)CN1C(=O)C2(OCCCO2)c3cc(C)ccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B19 compound treatment 278.6 91.7 0.48 282.9 94.7 0.49 0.6863 0.9999 1975130 ChemDiv1_010601 Nc1nc(SCC(=O)c2ccc(Br)cc2)c(C#N)cc1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B20 compound treatment 276.5 89.6 0.47 281.5 93.3 0.48 0.6734 0.9998 1975131 ChemDiv1_010602 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccsc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B21 compound treatment 259.9 73.0 0.38 265.9 77.7 0.4 0.5549 0.9996 1975132 ChemDiv1_010603 [O-][N+](=O)c1ccc(cc1)C(=O)NN2C(=O)c3cc(cc4cc(cc(C2=O)c34)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B22 compound treatment 272.2 85.3 0.45 279.6 91.4 0.47 0.6506 0.9995 1621158 ChemDiv1_010604 CCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccc(Br)cc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B23 mock treatment 279.0 92.1 0.48 279.3 91.1 0.47 0.6746 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 B24 mock treatment 75.2 -112.0 -0.58 77.6 -111.0 -0.58 -0.8185 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C01 compound treatment 285.1 98.2 0.51 287.1 98.9 0.51 0.7258 1.0 1975133 ChemDiv1_010605 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OCC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C02 compound treatment 284.7 97.8 0.51 296.2 108.0 0.56 0.7577 0.9989 1258342 ChemDiv1_010606 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)c3ccccc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C03 compound treatment 280.3 93.4 0.49 288.5 100.0 0.52 0.7132 0.9994 1975134 ChemDiv1_010607 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccc(c4)[N+](=O)[O-])C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C04 compound treatment 279.3 92.4 0.48 287.2 99.0 0.51 0.7047 0.9995 1975135 ChemDiv1_010608 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C05 compound treatment 277.6 90.7 0.47 287.5 99.3 0.52 0.6996 0.9991 1975136 ChemDiv1_010609 CCC(C(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(C)n2)(C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C06 compound treatment 276.8 89.9 0.47 286.5 98.3 0.51 0.6929 0.9991 1249737 ChemDiv1_010610 COc1ccccc1n2c(CSCC(=O)Nc3ccc4ccccc4c3)nc5ccccc5c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C07 compound treatment 277.5 90.6 0.47 287.3 99.1 0.51 0.6985 0.9991 1975137 ChemDiv1_010611 CCC1NC(Cc2c1[nH]c3ccccc23)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C08 compound treatment 271.2 84.3 0.44 288.0 99.8 0.52 0.6778 0.9967 1975138 ChemDiv1_010612 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C(=O)N)OC(=C(C#N)C1c3cccs3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C09 compound treatment 280.7 93.8 0.49 291.5 103.0 0.54 0.7257 0.9989 1975139 ChemDiv1_010613 CCOC(=O)C1=C(N)Oc2c(C1c3cc(cs3)[N+](=O)[O-])c(=O)oc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C10 compound treatment 282.0 95.1 0.5 291.1 103.0 0.53 0.729 0.9993 1975140 ChemDiv1_010614 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(OC)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C11 compound treatment 274.7 87.8 0.46 288.4 100.0 0.52 0.6922 0.998 1975141 ChemDiv1_010615 CCOC(=O)C1=C(OC(=C(C#N)C1c2cc3ccccc3nc2Cl)N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C12 compound treatment 274.0 87.1 0.45 286.9 98.7 0.51 0.6841 0.9982 1975142 ChemDiv1_010616 COCCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C13 compound treatment 273.4 86.5 0.45 287.4 99.2 0.52 0.6837 0.9978 1975143 ChemDiv1_010617 COc1ccc(NC(=O)CSc2nc(N)nc(SC)c2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C14 compound treatment 274.6 87.7 0.46 288.4 100.0 0.52 0.6918 0.9979 1393589 ChemDiv1_010618 NC1=C(C#N)C(C(=C(O1)c2ccccc2)C(=O)c3ccccc3)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C15 compound treatment 279.1 92.2 0.48 287.8 99.6 0.52 0.7062 0.9993 1975144 ChemDiv1_010619 NC(=O)CSc1nc(cc(c1C#N)c2ccccc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C16 compound treatment 280.2 93.3 0.49 285.3 97.1 0.5 0.7011 0.9998 1601979 ChemDiv1_010620 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(SC)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C17 compound treatment 279.7 92.8 0.48 282.9 94.7 0.49 0.6904 1.0 1132613 ChemDiv1_010621 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(Cc4ccccc4)c5cc(Br)c(O)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C18 compound treatment 275.9 89.0 0.46 285.7 97.5 0.51 0.6867 0.9991 1975145 ChemDiv1_010622 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(Cl)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C19 compound treatment 273.1 86.2 0.45 281.8 93.6 0.49 0.662 0.9992 1719028 ChemDiv1_010623 CCOC(=O)c1c(C)n(c2ccccc2)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C20 compound treatment 324.7 138.0 0.72 328.3 140.0 0.73 1.0233 1.0 1359860 ChemDiv1_010624 Nc1c(sc2nc(ccc12)c3ccccn3)C(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C21 compound treatment 278.1 91.2 0.48 277.5 89.3 0.46 0.6646 0.9999 1975146 ChemDiv1_010625 COc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N(C)N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C22 compound treatment 273.5 86.6 0.45 274.5 86.3 0.45 0.6367 1.0 1975147 ChemDiv1_010626 COc1ccc(Br)cc1C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C23 mock treatment 277.1 90.2 0.47 283.4 95.2 0.49 0.6826 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 C24 mock treatment 84.3 -103.0 -0.54 80.1 -108.0 -0.56 -0.7758 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D01 compound treatment 287.2 100.0 0.52 293.4 105.0 0.55 0.7567 0.9998 1975148 ChemDiv1_010627 Cc1ccccc1NC(=O)CSc2nc(N)c(C#N)c(c3cccs3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D02 compound treatment 281.2 94.3 0.49 285.3 97.1 0.5 0.7048 0.9999 1975149 ChemDiv1_010628 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D03 compound treatment 279.1 92.2 0.48 287.6 99.4 0.52 0.7055 0.9994 1975150 ChemDiv1_010629 COc1ccc(NC(=O)CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D04 compound treatment 278.2 91.3 0.48 284.9 96.7 0.5 0.6922 0.9996 1975151 ChemDiv1_010630 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])C(F)(F)C(F)(F)C(F)(F)F)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D05 compound treatment 279.3 92.4 0.48 287.1 98.9 0.51 0.7044 0.9995 1975152 ChemDiv1_010631 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D06 compound treatment 272.3 85.4 0.45 281.9 93.7 0.49 0.6594 0.999 1777550 ChemDiv1_010632 CCC1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D07 compound treatment 286.2 99.3 0.52 290.0 102.0 0.53 0.7405 0.9999 1975153 ChemDiv1_010633 CSc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)OC(C)C)CSc3nc(C)c(C)c(C)c3C#N)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D08 compound treatment 277.8 90.9 0.47 287.5 99.3 0.52 0.7003 0.9991 1975154 ChemDiv1_010634 CC1=NN(C(=O)C1=CNc2ccc(Br)cn2)c3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D09 compound treatment 280.6 93.7 0.49 289.2 101.0 0.52 0.7169 0.9994 1975155 ChemDiv1_010635 NC1=C(C#N)C(C2=C(O1)/C(=C/c3cccs3)/CN(Cc4ccccc4)C2)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D10 compound treatment 319.0 132.0 0.69 322.8 135.0 0.7 0.982 1.0 1975156 ChemDiv1_010636 Clc1ccc(cc1)C(=O)CSc2nc(ccc2C#N)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D11 compound treatment 272.4 85.5 0.45 286.4 98.2 0.51 0.6763 0.9978 1975157 ChemDiv1_010637 CCOC(=O)C1=C(OC(=C(C#N)C1c2cccnc2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D12 compound treatment 277.5 90.6 0.47 283.0 94.8 0.49 0.6827 0.9998 1183057 ChemDiv1_010638 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OCC(=O)N3CCCCC3)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D13 compound treatment 249.2 62.3 0.33 256.6 68.4 0.36 0.4812 0.999 1975158 ChemDiv1_010639 NC1=C(C#N)C(C2=C(O1)/C(=C/c3cccnc3)/CN(Cc4ccccc4)C2)c5cccnc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D14 compound treatment 273.3 86.4 0.45 287.1 98.9 0.51 0.6822 0.9979 1975159 ChemDiv1_010640 [O-][N+](=O)c1ccc(cc1)N2C(=O)C3C4OC(CNC(=O)COc5ccc(Cl)cc5Cl)(C=C4)C3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D15 compound treatment 274.9 88.0 0.46 285.4 97.2 0.51 0.6819 0.9989 1778631 ChemDiv1_010641 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2c(C)c([N+](=O)[O-])c(C)c([N+](=O)[O-])c2C)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D16 compound treatment 276.8 89.9 0.47 289.0 101.0 0.52 0.7021 0.9985 1317911 ChemDiv1_010642 Brc1ccc(cc1S(=O)(=O)N2CCCCC2)C(=O)Nc3ccc(cc3)C(=O)Oc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D17 compound treatment 276.4 89.5 0.47 285.6 97.4 0.51 0.6881 0.9992 1553768 ChemDiv1_010643 CCOC(=O)c1c(C)n(C2CCCCC2)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D18 compound treatment 274.6 87.7 0.46 280.8 92.6 0.48 0.6639 0.9997 1975160 ChemDiv1_010644 CC(C)CN/C(=C\1/C(=NN(C1=O)c2ccc(Br)cc2Br)C)/C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D19 compound treatment 282.0 95.1 0.5 289.4 101.0 0.53 0.7228 0.9996 1418950 ChemDiv1_010645 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)S(=O)(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D20 compound treatment 284.8 97.9 0.51 283.3 95.1 0.49 0.7107 0.9999 1738255 ChemDiv1_010646 CCOc1nc(C)cc(COC)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D21 compound treatment 302.0 115.0 0.6 307.9 120.0 0.62 0.8645 0.9998 1975161 ChemDiv1_010647 NS(=O)(=O)c1ccc(cc1)N2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D22 compound treatment 273.7 86.8 0.45 282.9 94.7 0.49 0.6683 0.9991 1470395 ChemDiv1_010648 CCOC(=O)C1=C(N)OC2=C(C(=O)CCC2)C31C(=O)Nc4ccc(Br)cc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D23 mock treatment 274.9 88.0 0.46 282.2 94.0 0.49 0.6701 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 D24 mock treatment 78.8 -108.0 -0.56 80.6 -108.0 -0.56 -0.7942 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E01 compound treatment 283.0 96.1 0.5 291.1 103.0 0.53 0.7327 0.9995 1871284 ChemDiv1_010649 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc5OCOc5c4)C(=O)OCCc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E02 compound treatment 282.1 95.2 0.5 286.6 98.4 0.51 0.7129 0.9999 1975162 ChemDiv1_010650 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C(F)(F)F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E03 compound treatment 275.0 88.1 0.46 289.7 101.0 0.53 0.6981 0.9977 1871368 ChemDiv1_010651 COc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E04 compound treatment 283.8 96.9 0.51 289.4 101.0 0.53 0.7294 0.9998 1975163 ChemDiv1_010652 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccccc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E05 compound treatment 278.1 91.2 0.48 286.3 98.1 0.51 0.697 0.9994 1874566 ChemDiv1_010653 CC(C)Nc1nc(NC(C)C)nc(Oc2ccc(=O)n(C)n2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E06 compound treatment 296.4 110.0 0.57 312.1 124.0 0.64 0.8593 0.9982 1975164 ChemDiv1_010654 COC(=O)C1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E07 compound treatment 286.5 99.6 0.52 298.6 110.0 0.57 0.7732 0.9988 1975165 ChemDiv1_010655 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccc2)c1C#N)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E08 compound treatment 279.9 93.0 0.49 289.8 102.0 0.53 0.7165 0.9991 1975166 ChemDiv1_010656 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccccc3Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E09 compound treatment 281.3 94.4 0.49 290.1 102.0 0.53 0.7228 0.9994 1975167 ChemDiv1_010657 CCOC(=O)C1=C(N)OC2=C(C1c3ccsc3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E10 compound treatment 306.4 120.0 0.62 305.8 118.0 0.61 0.8731 0.9999 1975168 ChemDiv1_010658 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4cccs4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E11 compound treatment 270.4 83.5 0.44 279.2 91.0 0.47 0.6425 0.9992 1975169 ChemDiv1_010659 COc1ccc(OC)c(/C=C\2/SC(=S)N(CNc3ccc(Br)cc3)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E12 compound treatment 247.2 60.3 0.31 256.5 68.3 0.35 0.4735 0.9982 1633191 ChemDiv1_010660 NC1=C(C#N)C2=CCN(Cc3ccccc3)CC2C4(C(=O)Nc5ccccc54)C1(C#N)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E13 compound treatment 273.9 87.0 0.45 286.7 98.5 0.51 0.683 0.9982 1975170 ChemDiv1_010661 CSc1nc(N)nc(SCC(=O)Nc2ccccc2[N+](=O)[O-])c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E14 compound treatment 273.5 86.6 0.45 288.4 100.0 0.52 0.6877 0.9975 1633852 ChemDiv1_010662 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E15 compound treatment 300.8 114.0 0.59 312.4 124.0 0.65 0.8767 0.9992 1975171 ChemDiv1_010663 CCc1nnc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E16 compound treatment 275.9 89.0 0.46 285.9 97.7 0.51 0.6874 0.999 1549855 ChemDiv1_010664 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(OCc3ccccc3)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E17 compound treatment 273.6 86.7 0.45 283.0 94.8 0.49 0.6683 0.9991 1975172 ChemDiv1_010665 CC(NC(=O)c1ccc(cc1)C2SCC(=O)N2Cc3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E18 compound treatment 292.4 106.0 0.55 296.3 108.0 0.56 0.7865 0.9999 1975173 ChemDiv1_010666 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(OCc4ccccc4)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E19 compound treatment 278.6 91.7 0.48 284.6 96.4 0.5 0.6926 0.9997 1975174 ChemDiv1_010667 COc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccccc4)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E20 compound treatment 274.7 87.8 0.46 279.5 91.3 0.47 0.6595 0.9998 1104609 ChemDiv1_010668 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(C)cc2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E21 compound treatment 280.9 94.0 0.49 282.8 94.6 0.49 0.6945 1.0 1591951 ChemDiv1_010669 Clc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E22 compound treatment 275.4 88.5 0.46 280.6 92.4 0.48 0.6661 0.9998 1975175 ChemDiv1_010670 CC(=O)c1ccc(cc1)N2C(=O)c3cccc4c(Br)c(cc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E23 mock treatment 277.6 90.7 0.47 282.0 93.8 0.49 0.6793 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 E24 mock treatment 77.4 -109.0 -0.57 78.1 -110.0 -0.57 -0.8086 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F01 compound treatment 280.6 93.7 0.49 289.1 101.0 0.52 0.7165 0.9994 1975176 ChemDiv1_010671 Nc1nc(SCC(=O)Nc2cccc(c2)[N+](=O)[O-])c(C#N)c(c3cccs3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F02 compound treatment 273.6 86.7 0.45 279.7 91.5 0.48 0.6561 0.9997 1975177 ChemDiv1_010672 [O-][N+](=O)c1cc2C(=O)N(C(=O)c3cc(cc(c1)c23)[N+](=O)[O-])c4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F03 compound treatment 278.2 91.3 0.48 285.0 96.8 0.5 0.6926 0.9996 1975178 ChemDiv1_010673 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3F)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F04 compound treatment 279.1 92.2 0.48 292.9 105.0 0.54 0.7249 0.9981 1578292 ChemDiv1_010674 CCOC(=O)c1c(NC(=O)c2sc3nc(N)c(C#N)cc3c2N)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F05 compound treatment 287.2 100.0 0.52 287.8 99.6 0.52 0.7361 1.0 1975179 ChemDiv1_010675 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(Cl)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F06 compound treatment 278.6 91.7 0.48 289.5 101.0 0.53 0.7106 0.9989 1303283 ChemDiv1_010676 CCOC(=O)c1c(CN2CCN(C)CC2)n(C)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F07 compound treatment 279.8 92.9 0.48 291.3 103.0 0.54 0.7216 0.9988 1975180 ChemDiv1_010677 CCOC(=O)CC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(F)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F08 compound treatment 276.2 89.3 0.47 288.4 100.0 0.52 0.6977 0.9985 1975181 ChemDiv1_010678 CC(=O)c1ccc(NC=C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F09 compound treatment 323.8 137.0 0.71 312.4 124.0 0.65 0.9615 0.9987 1975182 ChemDiv1_010679 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4cccc(F)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F10 compound treatment 276.2 89.3 0.47 288.8 101.0 0.52 0.6992 0.9984 1781400 ChemDiv1_010680 [O-][N+](=O)c1ccc(Cl)c(c1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F11 compound treatment 281.5 94.6 0.49 289.9 102.0 0.53 0.7228 0.9994 1230938 ChemDiv1_010681 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(SC)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F12 compound treatment 277.2 90.3 0.47 285.0 96.8 0.5 0.6889 0.9995 1400687 ChemDiv1_010682 CCOC(=O)C1=C(N)OC(=C(C(=O)OC(C)(C)C)C21C(=O)Nc3ccccc32)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F13 compound treatment 272.5 85.6 0.45 291.5 103.0 0.54 0.6955 0.9958 1975183 ChemDiv1_010683 COc1cccc(/C=C/2\SC(=O)N(CNc3cccc(Br)c3)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F14 compound treatment 273.8 86.9 0.45 281.4 93.2 0.48 0.6631 0.9995 1665907 ChemDiv1_010684 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC(=O)OCc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F15 compound treatment 278.8 91.9 0.48 289.3 101.0 0.53 0.7106 0.999 1604763 ChemDiv1_010685 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(O)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F16 compound treatment 272.4 85.5 0.45 283.3 95.1 0.49 0.6649 0.9987 1975184 ChemDiv1_010686 COc1ccc(cc1/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F17 compound treatment 275.1 88.2 0.46 287.1 98.9 0.51 0.6889 0.9985 1975185 ChemDiv1_010687 CN(C)c1nc(nc(n1)N2CC(=O)N(CCBr)C2=O)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F18 compound treatment 273.2 86.3 0.45 283.8 95.6 0.5 0.6697 0.9988 1975186 ChemDiv1_010688 [O-][N+](=O)c1cc(C=C2C(=O)NC(=S)NC2=O)ccc1Sc3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F19 compound treatment 276.4 89.5 0.47 282.4 94.2 0.49 0.6764 0.9997 1692416 ChemDiv1_010689 CCOC(=O)c1c(C)n(C)c2ccc(OC)c(c12)S(=O)(=O)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F20 compound treatment 277.2 90.3 0.47 283.4 95.2 0.49 0.683 0.9997 1975187 ChemDiv1_010690 COCc1cc(C)nc(SSc2nc(C)cc(COC)c2C#N)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F21 compound treatment 277.4 90.5 0.47 284.3 96.1 0.5 0.6871 0.9996 1975188 ChemDiv1_010691 [O-][N+](=O)c1ccc(cc1)C(=O)NN2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F22 compound treatment 277.4 90.5 0.47 283.5 95.3 0.5 0.6841 0.9997 1668589 ChemDiv1_010692 CC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccc(F)cc43)C(=C(N)O1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F23 mock treatment 280.7 93.8 0.49 284.1 95.9 0.5 0.6985 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 F24 mock treatment 77.5 -109.0 -0.57 79.3 -109.0 -0.57 -0.8038 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G01 compound treatment 283.2 96.3 0.5 291.3 103.0 0.54 0.7342 0.9995 1871263 ChemDiv1_010693 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4ccccc4F)C(=O)CC(C3)c5cccs5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G02 compound treatment 282.4 95.5 0.5 288.5 100.0 0.52 0.7209 0.9998 1975189 ChemDiv1_010694 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C(F)(F)F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G03 compound treatment 283.3 96.4 0.5 287.0 98.8 0.51 0.7187 0.9999 1871299 ChemDiv1_010695 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4ccc5OCOc5c4)C(=O)CC(C3)c6cccs6)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G04 compound treatment 275.5 88.6 0.46 290.6 102.0 0.53 0.7032 0.9976 1975190 ChemDiv1_010696 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccccc3I)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G05 compound treatment 278.9 92.0 0.48 290.7 102.0 0.53 0.7161 0.9987 1975191 ChemDiv1_010697 CN(C)c1nc(Oc2ccc(OCCOc3ccc(C)cc3)nn2)nc(n1)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G06 compound treatment 286.7 99.8 0.52 300.3 112.0 0.58 0.7802 0.9984 1975192 ChemDiv1_010698 Cc1cc(c2c(N)c(sc2n1)C(=O)Nc3cccc4ccccc34)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G07 compound treatment 278.0 91.1 0.48 291.3 103.0 0.54 0.715 0.9982 1486014 ChemDiv1_010699 O=C(CSc1nc2CCCc2cc1C#N)C3(CC4CC5CC(C4)C3)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G08 compound treatment 281.7 94.8 0.49 293.9 106.0 0.55 0.7382 0.9986 1975193 ChemDiv1_010700 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccccc3I)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G09 compound treatment 278.4 91.5 0.48 289.2 101.0 0.52 0.7088 0.9989 1348803 ChemDiv1_010701 CCOC(=O)C1=C(N)OC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G10 compound treatment 279.9 93.0 0.49 286.5 98.3 0.51 0.7044 0.9997 1975194 ChemDiv1_010702 CCOC(=O)c1cc2c(N)c(sc2nc1N)C(=O)Nc3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G11 compound treatment 274.1 87.2 0.46 284.2 96.0 0.5 0.6745 0.999 1975195 ChemDiv1_010703 [O-][N+](=O)c1cc(cc(c1)[N+](=O)[O-])C2=N/C(=C\c3ccccc3Br)/C(=O)O2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G12 compound treatment 276.2 89.3 0.47 289.5 101.0 0.53 0.7017 0.9982 1975196 ChemDiv1_010704 CCOc1ccc(Br)cc1C2C(=C(N)Oc3cc(C)oc(=O)c23)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G13 compound treatment 277.0 90.1 0.47 291.7 103.0 0.54 0.7128 0.9978 1975197 ChemDiv1_010705 CSc1nc(N)nc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G14 compound treatment 272.8 85.9 0.45 284.9 96.7 0.5 0.6723 0.9984 1975198 ChemDiv1_010706 CCOC(=O)c1ccc(NCN2C(=O)S/C(=C\c3ccc(cc3)C(=O)OC)/C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G15 compound treatment 298.2 111.0 0.58 308.3 120.0 0.62 0.852 0.9994 1975199 ChemDiv1_010707 CSc1nc(N)nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G16 compound treatment 281.6 94.7 0.49 290.3 102.0 0.53 0.7246 0.9994 1652926 ChemDiv1_010708 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OCc3ccccc3)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G17 compound treatment 275.8 88.9 0.46 284.4 96.2 0.5 0.6815 0.9993 1975200 ChemDiv1_010709 CCOC(=O)CC(=O)CSc1nc(cc(c1C#N)c2ccc(F)cc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G18 compound treatment 280.1 93.2 0.49 289.6 101.0 0.53 0.7165 0.9992 1975201 ChemDiv1_010710 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(OCc4ccccc4)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G19 compound treatment 266.8 79.9 0.42 267.7 79.5 0.41 0.5869 1.0 1975202 ChemDiv1_010711 COc1ccc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4cccs4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G20 compound treatment 273.3 86.4 0.45 279.9 91.7 0.48 0.6558 0.9996 1975203 ChemDiv1_010712 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccccc2F)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G21 compound treatment 278.2 91.3 0.48 281.1 92.9 0.48 0.6782 1.0 1975204 ChemDiv1_010713 CCOC(=O)c1cc(C#N)c(SCC(=O)c2ccc(Br)cc2)nc1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G22 compound treatment 271.8 84.9 0.44 278.6 90.4 0.47 0.6455 0.9996 1975205 ChemDiv1_010714 CC/1=NN(C(=O)\C1=C\Nc2cc(ccc2Cl)[N+](=O)[O-])c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G23 mock treatment 276.8 89.9 0.47 280.4 92.2 0.48 0.6705 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 G24 mock treatment 83.9 -103.0 -0.54 77.6 -111.0 -0.58 -0.7864 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H01 compound treatment 281.2 94.3 0.49 286.0 97.8 0.51 0.7073 0.9999 1975206 ChemDiv1_010715 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H02 compound treatment 283.9 97.0 0.51 288.5 100.0 0.52 0.7265 0.9999 1975207 ChemDiv1_010716 CC1=C(C(C(=C(N)O1)C#N)c2ccncc2)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H03 compound treatment 281.3 94.4 0.49 288.7 100.0 0.52 0.7176 0.9996 1975208 ChemDiv1_010717 CCCCOc1cccc(NC(=O)CSc2nc(N)nc(SC)c2C#N)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H04 compound treatment 283.3 96.4 0.5 288.9 101.0 0.52 0.7257 0.9998 1918195 ChemDiv1_010718 COc1ccc(cc1)N2C(c3ccc(Cl)cc3)S(=O)(=O)/C(=C/c4ccc(Cl)cc4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H05 compound treatment 278.7 91.8 0.48 288.3 100.0 0.52 0.7066 0.9992 1975209 ChemDiv1_010719 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(F)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H06 compound treatment 273.9 87.0 0.45 285.4 97.2 0.51 0.6782 0.9986 1282583 ChemDiv1_010720 CCOC(=O)c1c(CN2CCN(C)CC2)n(c3ccccc3)c4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H07 compound treatment 291.2 104.0 0.54 296.5 108.0 0.56 0.7828 0.9999 1975210 ChemDiv1_010721 CCOC(=O)C1=C(CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)OC(=C(C#N)C1c4ccccc4Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H08 compound treatment 277.3 90.4 0.47 289.4 101.0 0.53 0.7054 0.9985 1975211 ChemDiv1_010722 CC1=NN(C(=O)C1=CNc2ccccc2Cl)c3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H09 compound treatment 327.0 140.0 0.73 321.5 133.0 0.69 1.0067 0.9996 1975212 ChemDiv1_010723 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccc(Cl)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H10 compound treatment 273.2 86.3 0.45 290.1 102.0 0.53 0.6929 0.9968 1975213 ChemDiv1_010724 COc1ccc(CCNC(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccccc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H11 compound treatment 273.0 86.1 0.45 290.2 102.0 0.53 0.6925 0.9966 1975214 ChemDiv1_010725 CCOC(=O)C1=C(C)OC(=C(C(=O)OCCOC)C21C(=O)Nc3ccccc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H12 compound treatment 276.2 89.3 0.47 288.9 101.0 0.52 0.6995 0.9983 1736783 ChemDiv1_010726 CCC(=O)C1=C(C)OC(=C(C(=O)OC)C21C(=O)Nc3ccccc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H13 compound treatment 278.2 91.3 0.48 294.0 106.0 0.55 0.7257 0.9975 1975215 ChemDiv1_010727 Cc1ccc(/C=C/2\SC(=O)N(CNc3c(C)cc(Br)cc3C)C2=O)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H14 compound treatment 276.0 89.1 0.47 291.6 103.0 0.54 0.7087 0.9974 1648759 ChemDiv1_010728 Nc1ccc2nc(SCC(=O)Nc3ccc4c(c3)oc5ccccc54)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H15 compound treatment 288.2 101.0 0.53 297.1 109.0 0.57 0.7739 0.9994 1975216 ChemDiv1_010729 Cc1cc(nc(SCC(=O)Nc2ccccc2)c1C#N)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H16 compound treatment 279.3 92.4 0.48 285.9 97.7 0.51 0.6999 0.9997 1975217 ChemDiv1_010730 CCOC(=O)c1c(CNCCN(CC)CC)n(C)c2cc(Br)c(OC(=O)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H17 compound treatment 276.6 89.7 0.47 285.5 97.3 0.51 0.6885 0.9993 1329889 ChemDiv1_010731 COc1nc(nc(n1)N(CCOc2ccccc2)C#N)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H18 compound treatment 278.0 91.1 0.48 283.4 95.2 0.49 0.686 0.9998 1975218 ChemDiv1_010732 Cc1c(NC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-])c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H19 compound treatment 280.6 93.7 0.49 282.1 93.9 0.49 0.6908 1.0 1726677 ChemDiv1_010733 CCOC(=O)c1c(CSc2ccccc2)n(Cc3ccccc3)c4ccc(O)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H20 compound treatment 272.7 85.8 0.45 279.4 91.2 0.47 0.6517 0.9996 1975219 ChemDiv1_010734 CC(C)CCC1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H21 compound treatment 279.9 93.0 0.49 283.7 95.5 0.5 0.6941 0.9999 1975220 ChemDiv1_010735 [O-][N+](=O)c1cccc(c1)C(=O)NN2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H22 compound treatment 275.1 88.2 0.46 282.3 94.1 0.49 0.6712 0.9995 1135033 ChemDiv1_010736 CC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccc(Cl)cc32)C(=C(N)O1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H23 mock treatment 281.8 94.9 0.5 283.3 95.1 0.49 0.6996 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 H24 mock treatment 79.9 -107.0 -0.56 79.6 -109.0 -0.56 -0.7938 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I01 compound treatment 274.6 87.7 0.46 278.9 90.7 0.47 0.6569 0.9999 1871319 ChemDiv1_010737 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I02 compound treatment 279.7 92.8 0.48 288.5 100.0 0.52 0.711 0.9993 1975221 ChemDiv1_010738 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(Cl)c(Cl)c2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I03 compound treatment 281.8 94.9 0.5 290.8 103.0 0.53 0.7272 0.9993 1975222 ChemDiv1_010739 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccs4)C(=O)OCCOc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I04 compound treatment 276.9 90.0 0.47 290.0 102.0 0.53 0.7062 0.9982 1185389 ChemDiv1_010740 COc1cc(ccc1OC(=O)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I05 compound treatment 280.4 93.5 0.49 290.4 102.0 0.53 0.7205 0.9991 1975223 ChemDiv1_010741 C[N+](C)(CCN1C(=O)C2C(C(C=CC2c3ccccc3)c4ccccc4)C1=O)CC(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I06 compound treatment 275.8 88.9 0.46 288.7 100.0 0.52 0.6973 0.9983 1187832 ChemDiv1_010742 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I07 compound treatment 277.0 90.1 0.47 290.5 102.0 0.53 0.7084 0.9981 1975224 ChemDiv1_010743 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc4OCOc4c3Br)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I08 compound treatment 285.6 98.7 0.52 295.5 107.0 0.56 0.7585 0.9992 1975225 ChemDiv1_010744 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccccc3OC)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I09 compound treatment 277.0 90.1 0.47 285.2 97.0 0.5 0.6889 0.9994 1212011 ChemDiv1_010745 CCOc1nc(Nc2nc(cs2)c3ccccc3)nc(OCC)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I10 compound treatment 278.7 91.8 0.48 292.7 104.0 0.54 0.7227 0.9981 1311882 ChemDiv1_010746 CC(C)(C)C(=O)CSc1nc2CCCc2c(c3cccs3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I11 compound treatment 279.9 93.0 0.49 291.3 103.0 0.54 0.722 0.9988 1975226 ChemDiv1_010747 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I12 compound treatment 276.0 89.1 0.47 289.7 101.0 0.53 0.7017 0.998 1909173 ChemDiv1_010748 CC(=O)c1cc(C#N)c(SCc2ccc(Cl)c(Cl)c2)nc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I13 compound treatment 283.2 96.3 0.5 287.4 99.2 0.52 0.7198 0.9999 1975227 ChemDiv1_010749 FC(F)(F)c1cc(nc(SCC(=O)NCc2ccccc2)c1C#N)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I14 compound treatment 272.3 85.4 0.45 283.8 95.6 0.5 0.6664 0.9985 1234821 ChemDiv1_010750 CC(C)OC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I15 compound treatment 276.5 89.6 0.47 288.4 100.0 0.52 0.6988 0.9986 1975228 ChemDiv1_010751 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3cccc(c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I16 compound treatment 280.5 93.6 0.49 281.4 93.2 0.48 0.6878 1.0 1262708 ChemDiv1_010752 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OCC=C)cc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I17 compound treatment 257.5 70.6 0.37 262.8 74.6 0.39 0.5346 0.9997 1975229 ChemDiv1_010753 Cc1cc(c2c(N)c(sc2n1)C(=O)Nc3cccc(c3)C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I18 compound treatment 281.1 94.2 0.49 284.7 96.5 0.5 0.7022 1.0 1975230 ChemDiv1_010754 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccs3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I19 compound treatment 277.5 90.6 0.47 283.8 95.6 0.5 0.6856 0.9997 1975231 ChemDiv1_010755 [O-][N+](=O)c1ccc2c(CSc3nc4ccc(cc4s3)[N+](=O)[O-])c[nH]c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I20 compound treatment 279.2 92.3 0.48 286.8 98.6 0.51 0.7029 0.9995 1975232 ChemDiv1_010756 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I21 compound treatment 271.1 84.2 0.44 280.4 92.2 0.48 0.6495 0.9991 1975233 ChemDiv1_010757 O=C(Nc1ccc2C(=O)c3ccccc3C(=O)c2c1)c4cccc(c4)C(=O)Nc5ccc6C(=O)c7ccccc7C(=O)c6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I22 compound treatment 278.4 91.5 0.48 276.0 87.8 0.46 0.6602 0.9997 1975234 ChemDiv1_010758 [O-][N+](=O)c1cccc(c1)N2C(=O)c3cccc4c(Br)c(cc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I23 mock treatment 280.4 93.5 0.49 276.7 88.5 0.46 0.6702 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 I24 mock treatment 80.9 -106.0 -0.55 84.5 -104.0 -0.54 -0.7721 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J01 compound treatment 280.2 93.3 0.49 283.1 94.9 0.49 0.693 1.0 1661243 ChemDiv1_010759 CN1CCc2nc(SCC(=O)OCc3ccccc3)c(C#N)c(c4ccccc4)c2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J02 compound treatment 287.4 101.0 0.52 294.2 106.0 0.55 0.7603 0.9997 1182535 ChemDiv1_010760 Nc1nc(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c(C#N)c(c5cccs5)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J03 compound treatment 280.9 94.0 0.49 289.4 101.0 0.53 0.7187 0.9994 1975235 ChemDiv1_010761 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3Cl)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J04 compound treatment 282.9 96.0 0.5 291.0 103.0 0.53 0.732 0.9995 1975236 ChemDiv1_010762 COC(=O)c1ccc(NCN2C(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/SC2=S)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J05 compound treatment 280.0 93.1 0.49 291.1 103.0 0.53 0.7216 0.9989 1975237 ChemDiv1_010763 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J06 compound treatment 282.1 95.2 0.5 289.4 101.0 0.53 0.7231 0.9996 1776066 ChemDiv1_010764 Oc1c(C=c2sc3nc4ccccc4n3c2=O)cc(Br)cc1[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J07 compound treatment 284.1 97.2 0.51 298.8 111.0 0.57 0.7651 0.9981 1975238 ChemDiv1_010765 COc1ccc(NC(=O)CSc2nc(ccc2C#N)c3cccs3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J08 compound treatment 276.5 89.6 0.47 286.5 98.3 0.51 0.6918 0.999 1975239 ChemDiv1_010766 CC1=NN(C(=O)C1=CNc2ccc(Cl)cc2Cl)c3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J09 compound treatment 287.0 100.0 0.52 292.7 104.0 0.54 0.7533 0.9998 1578894 ChemDiv1_010767 CCOC(=O)C1=C(CSc2nc(N)c(C#N)c(c3cccs3)c2C#N)OC(=C(C#N)C1c4ccccc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J10 compound treatment 276.2 89.3 0.47 289.4 101.0 0.53 0.7014 0.9982 1724961 ChemDiv1_010768 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccc5OCOc5c4)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J11 compound treatment 275.4 88.5 0.46 289.8 102.0 0.53 0.6999 0.9978 1975240 ChemDiv1_010769 CC(=O)C1=C(C)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J12 compound treatment 277.1 90.2 0.47 288.3 100.0 0.52 0.7007 0.9988 1147389 ChemDiv1_010770 CCOC(=O)C1=C(C)OC(=C(C(=O)OC(C)(C)C)C21C(=O)Nc3ccccc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J13 compound treatment 275.2 88.3 0.46 289.2 101.0 0.52 0.697 0.9979 1975241 ChemDiv1_010771 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(Cl)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J14 compound treatment 278.0 91.1 0.48 291.6 103.0 0.54 0.7161 0.9981 1380438 ChemDiv1_010772 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J15 compound treatment 280.0 93.1 0.49 288.7 100.0 0.52 0.7128 0.9994 1975242 ChemDiv1_010773 COc1ccc(C2=NN(C(C2)c3ccc(C)o3)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J16 compound treatment 277.7 90.8 0.47 288.6 100.0 0.52 0.704 0.9988 1975243 ChemDiv1_010774 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2cccc(Cl)c2Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J17 compound treatment 278.2 91.3 0.48 287.0 98.8 0.51 0.6999 0.9993 1776173 ChemDiv1_010775 Cc1c(Br)c(nn1CC(=O)Nc2cc(Oc3cccnc3)cc(c2)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J18 compound treatment 274.8 87.9 0.46 282.5 94.3 0.49 0.6709 0.9995 1566248 ChemDiv1_010776 ONC(=O)CN1C(=O)C2(OCCO2)c3cc(Br)ccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J19 compound treatment 274.0 87.1 0.45 285.5 97.3 0.51 0.6789 0.9986 1975244 ChemDiv1_010777 Cc1nn(c(Cl)c1/C=C/2\N=C(OC2=O)c3ccc(C)c(c3)[N+](=O)[O-])c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J20 compound treatment 281.5 94.6 0.49 282.2 94.0 0.49 0.6945 1.0 1975245 ChemDiv1_010778 [O-][N+](=O)c1ccc(CSc2nc3C4CCN(CC4)c3cc2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J21 compound treatment 276.9 90.0 0.47 280.8 92.6 0.48 0.6724 0.9999 1975246 ChemDiv1_010779 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)c3ccc(N)cc3)c4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J22 compound treatment 280.3 93.4 0.49 285.2 97.0 0.5 0.7011 0.9999 1975247 ChemDiv1_010780 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccc(F)cc43)c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J23 mock treatment 274.5 87.6 0.46 279.6 91.4 0.47 0.6591 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 J24 mock treatment 74.8 -112.0 -0.58 81.4 -107.0 -0.56 -0.806 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K01 compound treatment 284.4 97.5 0.51 287.6 99.4 0.52 0.725 1.0 1975248 ChemDiv1_010781 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)cc3)C(=O)CC(C2)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K02 compound treatment 283.5 96.6 0.5 287.5 99.3 0.52 0.7213 0.9999 1129907 ChemDiv1_010782 NC1=C(C#N)C(c2cc(Br)ccc2F)c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K03 compound treatment 275.4 88.5 0.46 282.0 93.8 0.49 0.6712 0.9996 1871222 ChemDiv1_010783 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K04 compound treatment 279.4 92.5 0.48 287.7 99.5 0.52 0.7069 0.9994 1975249 ChemDiv1_010784 [O-][N+](=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccc(cc3)C(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K05 compound treatment 279.8 92.9 0.48 288.1 99.9 0.52 0.7099 0.9994 1591516 ChemDiv1_010785 CCOC(=O)c1sc2nc(N3CCOCC3)c4CN(C)CCc4c2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K06 compound treatment 274.9 88.0 0.46 288.7 100.0 0.52 0.694 0.9979 1975250 ChemDiv1_010786 CCOC(=O)c1c(CBr)n(CCBr)c2cc(Br)c(OC)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K07 compound treatment 258.2 71.3 0.37 256.9 68.7 0.36 0.5155 0.9998 1975251 ChemDiv1_010787 FC(F)(F)c1cc(nc(SCC(=O)C2CC2)c1C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K08 compound treatment 290.1 103.0 0.54 298.2 110.0 0.57 0.785 0.9996 1975252 ChemDiv1_010788 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccc(OC)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K09 compound treatment 278.8 91.9 0.48 287.9 99.7 0.52 0.7055 0.9993 1934900 ChemDiv1_010789 OC1(CC(=NN1C(=O)c2cccc(Br)c2)C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K10 compound treatment 280.5 93.6 0.49 294.0 106.0 0.55 0.7341 0.9983 1975253 ChemDiv1_010790 CC(C)(C)OC(=O)CSc1nc2CCCc2c(c3cccs3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K11 compound treatment 275.6 88.7 0.46 289.2 101.0 0.52 0.6984 0.998 1494447 ChemDiv1_010791 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc(Cl)c(O)c(Cl)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K12 compound treatment 276.6 89.7 0.47 288.5 100.0 0.52 0.6995 0.9986 1975254 ChemDiv1_010792 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K13 compound treatment 279.4 92.5 0.48 294.7 106.0 0.55 0.7327 0.9977 1975255 ChemDiv1_010793 [O-][N+](=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K14 compound treatment 276.5 89.6 0.47 290.5 102.0 0.53 0.7065 0.998 1730692 ChemDiv1_010794 NC1=C(C#N)C(c2ccc(OCc3ccccc3)cc2)c4c(O1)c5ccccc5oc4=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K15 compound treatment 273.7 86.8 0.45 284.5 96.3 0.5 0.6741 0.9988 1975256 ChemDiv1_010795 NC1=C(C#N)C(c2ccc(F)c(Br)c2)c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K16 compound treatment 279.4 92.5 0.48 288.4 100.0 0.52 0.7095 0.9993 1975257 ChemDiv1_010796 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K17 compound treatment 273.8 86.9 0.45 280.9 92.7 0.48 0.6613 0.9995 1925625 ChemDiv1_010797 Brc1cccc(c1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K18 compound treatment 287.0 100.0 0.52 290.7 102.0 0.53 0.746 1.0 1975258 ChemDiv1_010798 CCOC(=O)C1=C(CSc2nc3CCCc3cc2C#N)OC(=C(C#N)C1c4cccs4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K19 compound treatment 274.7 87.8 0.46 286.4 98.2 0.51 0.6848 0.9986 1720450 ChemDiv1_010799 Cc1cccc(c1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K20 compound treatment 272.6 85.7 0.45 276.2 88.0 0.46 0.6396 0.9999 1975259 ChemDiv1_010800 CC1=C(C(C(=C(N)O1)C#N)c2cccs2)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K21 compound treatment 276.6 89.7 0.47 279.5 91.3 0.47 0.6665 1.0 1975260 ChemDiv1_010801 COC(=O)c1ccc(/C=C\2/SC(=O)N(CNc3ccc(OC)cc3OC)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K22 compound treatment 275.2 88.3 0.46 281.8 93.6 0.49 0.6698 0.9996 1711890 ChemDiv1_010802 O=c1[nH]n(c2ncnc3sc4CCCCc4c23)c(=O)c5cccc6cccc1c65 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K23 mock treatment 275.4 88.5 0.46 282.7 94.5 0.49 0.6738 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 K24 mock treatment 79.1 -108.0 -0.56 80.0 -108.0 -0.56 -0.7953 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L01 compound treatment 284.7 97.8 0.51 293.3 105.0 0.55 0.7471 0.9994 1975261 ChemDiv1_010803 Nc1nc(SCC(=O)NCc2ccccc2)c(C#N)c(c1C#N)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L02 compound treatment 283.6 96.7 0.5 291.7 103.0 0.54 0.7371 0.9995 1975262 ChemDiv1_010804 COc1ccc(cc1)N(C)CN2C(=O)/C(=C\c3cccc(F)c3)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L03 compound treatment 283.3 96.4 0.5 285.8 97.6 0.51 0.7143 1.0 1651380 ChemDiv1_010805 CC(C)OC(=O)C1=C(N)OC2=C(C1c3ccccc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L04 compound treatment 290.7 104.0 0.54 298.1 110.0 0.57 0.7868 0.9997 1975263 ChemDiv1_010806 CCCCOc1cccc(NC(=O)CSc2nc(C)cc(c2C#N)c3cccnc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L05 compound treatment 279.4 92.5 0.48 286.4 98.2 0.51 0.7022 0.9996 1975264 ChemDiv1_010807 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3Br)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L06 compound treatment 279.0 92.1 0.48 291.1 103.0 0.53 0.718 0.9986 1975265 ChemDiv1_010808 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3ccccc3C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L07 compound treatment 276.4 89.5 0.47 278.6 90.4 0.47 0.6624 1.0 1975266 ChemDiv1_010809 CC(C)OC(=O)CC(=O)CSc1nc2CCCCc2c(c3cccs3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L08 compound treatment 274.1 87.2 0.46 283.2 95.0 0.49 0.6708 0.9992 1975267 ChemDiv1_010810 CCOc1ccc(NC=C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L09 compound treatment 226.9 40.0 0.21 232.7 44.5 0.23 0.3111 0.9987 1191563 ChemDiv1_010811 CN1CCc2nc(SCC(=O)OC(C)(C)C)c(C#N)c(c3cccs3)c2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L10 compound treatment 276.6 89.7 0.47 288.0 99.8 0.52 0.6977 0.9987 1508594 ChemDiv1_010812 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OCC(=O)N3CCOCC3)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L11 compound treatment 277.6 90.7 0.47 288.3 100.0 0.52 0.7025 0.9989 1217290 ChemDiv1_010813 COC(=O)C1=C(C)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L12 compound treatment 277.1 90.2 0.47 290.9 103.0 0.53 0.7102 0.998 1664772 ChemDiv1_010814 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(Cl)cc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L13 compound treatment 276.8 89.9 0.47 285.5 97.3 0.51 0.6893 0.9993 1869163 ChemDiv1_010815 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(cc4)[N+](=O)[O-])C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L14 compound treatment 275.3 88.4 0.46 287.2 99.0 0.51 0.69 0.9985 1578459 ChemDiv1_010816 Cc1c(NC(=O)CN(c2cc(C)ccc2C)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L15 compound treatment 277.9 91.0 0.47 285.0 96.8 0.5 0.6915 0.9996 1975268 ChemDiv1_010817 CCOc1ccc2ccccc2c1/C=C/3\N=C(OC3=O)c4cc(cc(c4)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L16 compound treatment 281.5 94.6 0.49 291.5 103.0 0.54 0.7286 0.9991 1975269 ChemDiv1_010818 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2ccc(F)c(Br)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L17 compound treatment 279.0 92.1 0.48 287.8 99.6 0.52 0.7058 0.9993 1204814 ChemDiv1_010819 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(OC(=O)C)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L18 compound treatment 274.0 87.1 0.45 283.9 95.7 0.5 0.673 0.999 1545268 ChemDiv1_010820 Cc1ccc2N(CC(=O)O)C(=O)C3(OCCCO3)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L19 compound treatment 277.2 90.3 0.47 282.1 93.9 0.49 0.6782 0.9998 1975270 ChemDiv1_010821 CCOC(=O)CCCCC(=O)c1[nH]c(=O)[nH]c1CSc2nc(N)c(C#N)cc2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L20 compound treatment 276.8 89.9 0.47 278.8 90.6 0.47 0.6646 1.0 1486404 ChemDiv1_010822 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(Br)cc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L21 compound treatment 273.9 87.0 0.45 278.4 90.2 0.47 0.6525 0.9999 1975271 ChemDiv1_010823 CC/1=NN(C(=O)\C1=C\Nc2cc(cc([N+](=O)[O-])c2O)[N+](=O)[O-])c3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L22 compound treatment 275.7 88.8 0.46 280.7 92.5 0.48 0.6676 0.9998 1975272 ChemDiv1_010824 COCCOC(=O)C1=C(N)OC(=C(C(=O)C)C21C(=O)Nc3ccccc32)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L23 mock treatment 276.4 89.5 0.47 280.5 92.3 0.48 0.6694 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 L24 mock treatment 82.6 -104.0 -0.54 77.2 -111.0 -0.58 -0.7927 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M01 compound treatment 281.8 94.9 0.5 288.7 100.0 0.52 0.7195 0.9996 1975273 ChemDiv1_010825 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc5OCOc5c4)C(=O)OCCOc6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M02 compound treatment 279.6 92.7 0.48 285.0 96.8 0.5 0.6977 0.9998 1128556 ChemDiv1_010826 COC(=O)c1sc2nc(cc(c3ccc(F)cc3)c2c1N)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M03 compound treatment 278.7 91.8 0.48 286.2 98.0 0.51 0.6988 0.9995 1871420 ChemDiv1_010827 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc(C)c(c4)[N+](=O)[O-])C(=O)OC5CCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M04 compound treatment 282.2 95.3 0.5 286.0 97.8 0.51 0.711 0.9999 1172840 ChemDiv1_010828 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M05 compound treatment 278.6 91.7 0.48 286.6 98.4 0.51 0.6999 0.9995 1975274 ChemDiv1_010829 Cc1nc(NC(=O)(=O)c2ccc(C)cc2)sc1NC(=O)OCCNC(=O)COc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M06 compound treatment 276.2 89.3 0.47 288.6 100.0 0.52 0.6984 0.9984 1975275 ChemDiv1_010830 CCCCOc1cccc(NC(=O)CSc2nc(C)cc(C)c2C#N)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M07 compound treatment 279.6 92.7 0.48 278.2 90.0 0.47 0.6728 0.9999 1975276 ChemDiv1_010831 COCc1cc(C)nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M08 compound treatment 301.9 115.0 0.6 305.5 117.0 0.61 0.8554 1.0 1334338 ChemDiv1_010832 CCOC(=O)C1=C(CSc2nc3CCCc3cc2C#N)OC(=C(C#N)C1c4cccc(OCc5ccccc5)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M09 compound treatment 287.0 100.0 0.52 291.7 103.0 0.54 0.7497 0.9999 1975277 ChemDiv1_010833 CCOC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(c1C#N)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M10 compound treatment 278.5 91.6 0.48 299.4 111.0 0.58 0.7466 0.9956 1554542 ChemDiv1_010834 CC1CC=C2C(C1)C3(C(=O)Nc4ccccc43)C(C#N)(C#N)C(=C2C#N)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M11 compound treatment 278.0 91.1 0.48 287.3 99.1 0.51 0.7003 0.9992 1975278 ChemDiv1_010835 COc1ccc(cc1)c2cc(nc(SCC(=O)O)c2C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M12 compound treatment 277.6 90.7 0.47 285.2 97.0 0.5 0.6911 0.9995 1975279 ChemDiv1_010836 NC1=C(C#N)C(C2=C(O1)/C(=C/c3ccsc3)/CN(Cc4ccccc4)C2)c5ccsc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M13 compound treatment 280.6 93.7 0.49 289.1 101.0 0.52 0.7165 0.9994 1975280 ChemDiv1_010837 NC(=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M14 compound treatment 273.3 86.4 0.45 288.9 101.0 0.52 0.6888 0.9973 1975281 ChemDiv1_010838 CSc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)C)C)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M15 compound treatment 278.9 92.0 0.48 281.6 93.4 0.49 0.6827 1.0 1320307 ChemDiv1_010839 CCOC(=O)C(C)Sc1nc2CCCCc2c(c3cccs3)c1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M16 compound treatment 277.5 90.6 0.47 281.5 93.3 0.48 0.6771 0.9999 1975282 ChemDiv1_010840 CC(=O)Nc1cccc(NC(=O)CSc2nc(C)c(C)c(C)c2C#N)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M17 compound treatment 271.9 85.0 0.44 283.9 95.7 0.5 0.6653 0.9984 1975283 ChemDiv1_010841 Cc1ccc2nc3[nH]c4ccccc4c3nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M18 compound treatment 274.8 87.9 0.46 283.8 95.6 0.5 0.6756 0.9992 1975284 ChemDiv1_010842 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3cccs3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M19 compound treatment 299.9 113.0 0.59 305.0 117.0 0.61 0.8461 0.9999 1975285 ChemDiv1_010843 Cc1cc(c(C#N)c(SCC(=O)NCCc2ccccc2)n1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M20 compound treatment 280.8 93.9 0.49 291.5 103.0 0.54 0.7261 0.999 1975286 ChemDiv1_010844 CC1=C(C(C(=C(N)O1)C#N)c2ccc(Cl)cc2)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M21 compound treatment 277.0 90.1 0.47 278.7 90.5 0.47 0.665 1.0 1975287 ChemDiv1_010845 COCc1cc(C)c(C#N)c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M22 compound treatment 270.6 83.7 0.44 279.1 90.9 0.47 0.6429 0.9992 1776560 ChemDiv1_010846 [O-][N+](=O)c1cc2C(=O)N(C(=O)c3cc(cc(c1)c23)[N+](=O)[O-])c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M23 mock treatment 274.6 87.7 0.46 281.8 93.6 0.49 0.6675 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 M24 mock treatment 192.7 5.84 0.03 193.0 4.76 0.02 0.039 0.9947 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N01 compound treatment 270.7 83.8 0.44 291.5 103.0 0.54 0.6888 0.9948 1975288 ChemDiv1_010847 Cc1cccc(NC(=O)CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N02 compound treatment 283.5 96.6 0.5 290.0 102.0 0.53 0.7305 0.9997 1312702 ChemDiv1_010848 Nc1nc(SCC(=O)c2cc3ccccc3oc2=O)c(C#N)c(c1C#N)c4cccc(O)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N03 compound treatment 315.3 128.0 0.67 320.4 132.0 0.69 0.9595 0.9999 1975289 ChemDiv1_010849 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccc(C#N)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N04 compound treatment 281.3 94.4 0.49 284.5 96.3 0.5 0.7022 1.0 1975290 ChemDiv1_010850 COc1cc(/C=C\2/SC(=O)N(CNc3ccccc3C)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N05 compound treatment 277.1 90.2 0.47 284.2 96.0 0.5 0.6856 0.9996 1975291 ChemDiv1_010851 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3I)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N06 compound treatment 279.7 92.8 0.48 284.5 96.3 0.5 0.6963 0.9999 1975292 ChemDiv1_010852 CC(=O)Nc1ccc(NC=C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N07 compound treatment 280.6 93.7 0.49 291.9 104.0 0.54 0.7268 0.9988 1645343 ChemDiv1_010853 NC1=C(C#N)C2(C(=O)Nc3ccccc32)C(=C(N)S1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N08 compound treatment 276.7 89.8 0.47 287.5 99.3 0.52 0.6962 0.9988 1975293 ChemDiv1_010854 CC/1=NN(C(=O)\C1=C/Nc2ccc([N+](=O)[O-])c(c2)[N+](=O)[O-])c3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N09 compound treatment 253.8 66.9 0.35 260.4 72.2 0.38 0.5122 0.9994 1220507 ChemDiv1_010855 CN1CCc2nc(SCC(=O)OCc3ccccc3)c(C#N)c(c4cccs4)c2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N10 compound treatment 276.9 90.0 0.47 288.6 100.0 0.52 0.701 0.9986 1360311 ChemDiv1_010856 CCOC(=O)c1c(CN2CCOCC2)n(C3CCCCC3)c4cc(Br)c(O)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N11 compound treatment 281.3 94.4 0.49 288.4 100.0 0.52 0.7165 0.9996 1975294 ChemDiv1_010857 CCc1nnc(NC(=O)c2sc3nc(C)cc(c3c2N)C(F)(F)F)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N12 compound treatment 240.2 53.3 0.28 245.9 57.7 0.3 0.4087 0.9993 1975295 ChemDiv1_010858 CCN1C/C(=C\c2ccccc2F)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N13 compound treatment 274.8 87.9 0.46 286.8 98.6 0.51 0.6867 0.9985 1101575 ChemDiv1_010859 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(c4)[N+](=O)[O-])C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N14 compound treatment 276.0 89.1 0.47 283.4 95.2 0.49 0.6786 0.9995 1975296 ChemDiv1_010860 COc1ccc(CCNC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N15 compound treatment 275.7 88.8 0.46 285.6 97.4 0.51 0.6856 0.999 1975297 ChemDiv1_010861 CCCCCCCCCC(=O)Nc1ccc(cc1)C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N16 compound treatment 274.7 87.8 0.46 286.8 98.6 0.51 0.6863 0.9984 1975298 ChemDiv1_010862 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2ccccc2Br)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N17 compound treatment 274.3 87.4 0.46 284.8 96.6 0.5 0.6775 0.9989 1615067 ChemDiv1_010863 CCOC(=O)c1c(C)n(Cc2ccccc2)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N18 compound treatment 262.1 75.2 0.39 275.0 86.8 0.45 0.5964 0.9976 1975299 ChemDiv1_010864 Cc1ccc2NC(=O)C3(NN=C(S3)c4ccccc4O)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N19 compound treatment 290.4 104.0 0.54 294.1 106.0 0.55 0.771 1.0 1975300 ChemDiv1_010865 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c3ccc([N+](=O)[O-])c1c23)c4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N20 compound treatment 274.6 87.7 0.46 283.8 95.6 0.5 0.6749 0.9992 1474535 ChemDiv1_010866 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(F)cc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N21 compound treatment 273.0 86.1 0.45 279.3 91.1 0.47 0.6525 0.9997 1975301 ChemDiv1_010867 Cc1cccc(c1)C(=O)NN2C(=O)c3cccc4c(Br)c(cc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N22 compound treatment 279.7 92.8 0.48 281.2 93.0 0.48 0.6841 1.0 1406548 ChemDiv1_010868 COC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N23 mock treatment 279.2 92.3 0.48 282.0 93.8 0.49 0.6852 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 N24 mock treatment 189.5 2.64 0.01 190.2 1.96 0.01 0.017 0.9891 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O01 compound treatment 277.5 90.6 0.47 288.0 99.8 0.52 0.701 0.9989 1871225 ChemDiv1_010869 COC(=O)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O02 compound treatment 280.7 93.8 0.49 287.1 98.9 0.51 0.7095 0.9997 1975302 ChemDiv1_010870 COC(=O)CSc1nc(cc(c1C#N)c2ccc(F)cc2)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O03 compound treatment 279.9 93.0 0.49 283.5 95.3 0.5 0.6933 0.9999 1975303 ChemDiv1_010871 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCOC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O04 compound treatment 317.5 131.0 0.68 309.0 121.0 0.63 0.9258 0.9992 1975304 ChemDiv1_010872 Brc1ccc(cc1)C(=O)CSc2nc(ccc2C#N)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O05 compound treatment 281.1 94.2 0.49 285.9 97.7 0.51 0.7066 0.9999 1975305 ChemDiv1_010873 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(Br)s2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O06 compound treatment 282.2 95.3 0.5 285.6 97.4 0.51 0.7095 1.0 1975306 ChemDiv1_010874 CCS(=O)(=O)CCSc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O07 compound treatment 279.6 92.7 0.48 282.1 93.9 0.49 0.6871 1.0 1975307 ChemDiv1_010875 COc1ccc([C@H]2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N)c([N+](=O)[O-])c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O08 compound treatment 278.1 91.2 0.48 290.6 102.0 0.53 0.7128 0.9985 1975308 ChemDiv1_010876 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(F)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O09 compound treatment 314.7 128.0 0.67 320.7 132.0 0.69 0.9584 0.9999 1975309 ChemDiv1_010877 Cc1cc(c(C#N)c(SCC(=O)Nc2ccccc2C)n1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O10 compound treatment 275.7 88.8 0.46 282.2 94.0 0.49 0.6731 0.9997 1678275 ChemDiv1_010878 CCOC(=O)C1=C(N)OC2=C(C(=O)CCC2)C31C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O11 compound treatment 282.8 95.9 0.5 289.4 101.0 0.53 0.7257 0.9997 1975310 ChemDiv1_010879 COc1ccc(NC(=O)c2sc3nc(C)cc(c3c2N)C(F)(F)F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O12 compound treatment 201.1 14.2 0.07 200.0 11.8 0.06 0.0958 0.9953 1975311 ChemDiv1_010880 CC(C)N1C/C(=C\c2ccccc2F)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccccc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O13 compound treatment 260.3 73.4 0.38 260.0 71.8 0.37 0.5347 0.9999 1975312 ChemDiv1_010881 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)NCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O14 compound treatment 252.4 65.5 0.34 251.4 63.2 0.33 0.4739 0.9998 1975313 ChemDiv1_010882 CC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(OCc3ccccc3)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O15 compound treatment 282.3 95.4 0.5 288.7 100.0 0.52 0.7213 0.9997 1188304 ChemDiv1_010883 NC1=C(C#N)C(c2cc(Br)cs2)c3c(O1)c4ccccc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O16 compound treatment 278.2 91.3 0.48 290.6 102.0 0.53 0.7132 0.9985 1975314 ChemDiv1_010884 Cc1nc(SCC(=O)Nc2ccc(cc2)C(=O)N)c(C#N)c(C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O17 compound treatment 286.1 99.2 0.52 286.6 98.4 0.51 0.7276 1.0 1975315 ChemDiv1_010885 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2cccc(F)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O18 compound treatment 301.9 115.0 0.6 296.9 109.0 0.56 0.8237 0.9995 1975316 ChemDiv1_010886 CCOC(=O)C1=C(CSc2nc3CCCCCc3cc2C#N)OC(=C(C#N)C1c4ccc(SC)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O19 compound treatment 275.2 88.3 0.46 281.4 93.2 0.48 0.6683 0.9997 1449111 ChemDiv1_010887 Cc1cccc(C)c1Nc2nc3nonc3nc2Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O20 compound treatment 278.5 91.6 0.48 283.1 94.9 0.49 0.6867 0.9999 1975317 ChemDiv1_010888 CC1=C(C(C(=C(N)O1)C#N)c2ccsc2)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O21 compound treatment 272.6 85.7 0.45 281.3 93.1 0.48 0.6583 0.9992 1975318 ChemDiv1_010889 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2Cl)[N+](=O)[O-])c3ccccc3C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O22 compound treatment 276.2 89.3 0.47 278.7 90.5 0.47 0.6621 1.0 1975319 ChemDiv1_010890 CC/1=NN(C(=O)\C1=C/Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O23 mock treatment 283.2 96.3 0.5 278.8 90.6 0.47 0.6882 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 O24 mock treatment 96.5 -90.4 -0.47 93.9 -94.3 -0.49 -0.6801 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P01 compound treatment 285.5 98.6 0.51 284.8 96.6 0.5 0.7188 0.9999 1975320 ChemDiv1_010891 COCCOC(=O)C1=C(N)Oc2c(C1c3ccc(F)cc3)c(=O)oc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P02 compound treatment 287.3 100.0 0.52 289.4 101.0 0.53 0.7423 1.0 1975321 ChemDiv1_010892 Cc1ccc(o1)c2cc(C)nc(SCC(=O)c3ccc(Br)cc3)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P03 compound treatment 301.2 114.0 0.6 303.8 116.0 0.6 0.8465 1.0 1975322 ChemDiv1_010893 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccccc4I)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P04 compound treatment 280.0 93.1 0.49 283.1 94.9 0.49 0.6922 1.0 1975323 ChemDiv1_010894 COc1cc(/C=C\2/SC(=O)N(CNc3ccccc3F)C2=O)cc(OC)c1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P05 compound treatment 281.0 94.1 0.49 285.2 97.0 0.5 0.7036 0.9999 1975324 ChemDiv1_010895 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(I)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P06 compound treatment 280.2 93.3 0.49 283.8 95.6 0.5 0.6956 1.0 1975325 ChemDiv1_010896 CC(=O)Nc1ccc(NC=C2C(=NN(C2=O)c3ccc(C)cc3)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P07 compound treatment 296.2 109.0 0.57 301.9 114.0 0.59 0.8211 0.9998 1975326 ChemDiv1_010897 COc1ccc(/C=C/2\CCCC3=C2OC(=C(C#N)C3c4ccc(OC)cc4)N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P08 compound treatment 280.2 93.3 0.49 288.2 100.0 0.52 0.7117 0.9995 1742371 ChemDiv1_010898 CCOC(=O)c1sc(NC(=O)c2cc3cccc(CC=C)c3oc2=O)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P09 compound treatment 283.7 96.8 0.51 290.0 102.0 0.53 0.7312 0.9997 1678774 ChemDiv1_010899 CCOC(=O)C1=C(CSc2nc3CCCCc3c(c4cccs4)c2C#N)OC(=C(C#N)C1c5ccc(Cl)cc5)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P10 compound treatment 278.9 92.0 0.48 286.4 98.2 0.51 0.7003 0.9995 1444877 ChemDiv1_010900 Oc1ccc(cc1)n2c(=O)c3ccc4c(=O)n(c5ccc(O)cc5)c(=O)c6ccc(c2=O)c3c46 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P11 compound treatment 280.0 93.1 0.49 286.3 98.1 0.51 0.704 0.9997 1975327 ChemDiv1_010901 COCCOC(=O)C1=C(N)OC2=C(C1c3ccncc3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P12 compound treatment 221.1 34.2 0.18 219.1 30.9 0.16 0.2397 0.9986 1975328 ChemDiv1_010902 CCN1C/C(=C\c2ccc(F)cc2)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P13 compound treatment 278.1 91.2 0.48 283.2 95.0 0.49 0.6856 0.9998 1322056 ChemDiv1_010903 CC(C)Nc1nc2nonc2nc1Nc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P14 compound treatment 274.6 87.7 0.46 278.3 90.1 0.47 0.6547 0.9999 1975329 ChemDiv1_010904 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(s2)C(C)(C)C)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P15 compound treatment 279.0 92.1 0.48 287.6 99.4 0.52 0.7051 0.9994 1975330 ChemDiv1_010905 CCOC(=O)CN1C(=N)N(CC1=O)c2nc(nc(n2)N(C)C)N(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P16 compound treatment 276.9 90.0 0.47 286.6 98.4 0.51 0.6937 0.9991 1455607 ChemDiv1_010906 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)N2CCN(CC2)C(=O)c3cccc(c3)S(=O)(=O)N(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P17 compound treatment 278.0 91.1 0.48 283.7 95.5 0.5 0.6871 0.9998 1495566 ChemDiv1_010907 CCOC(=O)c1c(CSc2ccc(C)cc2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P18 compound treatment 279.7 92.8 0.48 284.1 95.9 0.5 0.6948 0.9999 1975331 ChemDiv1_010908 COc1ccc(cc1)C2=C(C3C4C(C2C3=O)C(=O)N(C4=O)c5cccc6ccccc56)c7ccc(OC)cc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P19 compound treatment 250.1 63.2 0.33 258.1 69.9 0.36 0.4901 0.9989 1975332 ChemDiv1_010909 NS(=O)(=O)c1ccc(cc1)N2C(=O)c3cc(cc4cc(cc(C2=O)c34)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P20 compound treatment 280.5 93.6 0.49 281.5 93.3 0.48 0.6882 1.0 1553530 ChemDiv1_010910 COC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(Br)cc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P21 compound treatment 285.0 98.1 0.51 292.0 104.0 0.54 0.7434 0.9997 1975333 ChemDiv1_010911 OC(=O)c1cc(ccc1Cl)N2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P22 compound treatment 280.2 93.3 0.49 283.7 95.5 0.5 0.6952 1.0 1975334 ChemDiv1_010912 CCOC(=O)c1sc2nc(C)cc(COC)c2c1NC(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P23 mock treatment 278.5 91.6 0.48 280.8 92.6 0.48 0.6783 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.617 P24 mock treatment 98.3 -88.6 -0.46 94.7 -93.5 -0.49 -0.6705 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A01 compound treatment 291.5 106.0 0.55 290.2 104.0 0.54 0.7737 0.9999 1655149 ChemDiv1_010913 CON(c1nc(OC)nc(n1)N(C)C)S(=O)(=O)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A02 compound treatment 283.2 97.8 0.51 282.3 96.1 0.5 0.714 0.9999 1975335 ChemDiv1_010914 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(NC(=O)C(F)(F)F)c3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A03 compound treatment 284.1 98.7 0.51 287.4 101.0 0.53 0.7361 0.9999 1975336 ChemDiv1_010915 CC/1=NN(C(=O)\C1=C/Nc2cc(cc(c2)[N+](=O)[O-])[N+](=O)[O-])c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A04 compound treatment 287.2 102.0 0.53 293.5 107.0 0.56 0.77 0.9997 1975337 ChemDiv1_010916 NC1=C(C#N)C(C(=C(O1)c2ccccc2)C(=O)c3ccccc3)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A05 compound treatment 278.8 93.4 0.49 282.7 96.5 0.5 0.6993 0.9999 1975338 ChemDiv1_010917 Clc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A06 compound treatment 283.7 98.3 0.51 283.1 96.9 0.5 0.7188 1.0 1323946 ChemDiv1_010918 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(C)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A07 compound treatment 282.0 96.6 0.5 288.2 102.0 0.53 0.7313 0.9997 1975339 ChemDiv1_010919 CCOC(=O)c1c(CBr)n(C)c2ccc(OS(=O)(=O)c3ccc(C)cc3)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A08 compound treatment 276.9 91.5 0.48 290.9 105.0 0.54 0.7224 0.9979 1975340 ChemDiv1_010920 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)C(F)(F)F)c3ccncc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A09 compound treatment 279.2 93.8 0.49 286.5 100.0 0.52 0.7147 0.9995 1185796 ChemDiv1_010921 Clc1ccc(cc1S(=O)(=O)Nc2ccc(NC(=O)c3ccccc3)cc2)C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A10 compound treatment 280.0 94.6 0.49 290.3 104.0 0.54 0.7316 0.9989 1975341 ChemDiv1_010922 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A11 compound treatment 277.6 92.2 0.48 284.4 98.2 0.51 0.7011 0.9996 1552070 ChemDiv1_010923 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4C(=O)O)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A12 compound treatment 276.5 91.1 0.48 284.7 98.5 0.51 0.6981 0.9993 1975342 ChemDiv1_010924 NC1=C(C#N)C(C(=C(O1)c2ccccc2)n3cnc(c3)[N+](=O)[O-])c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A13 compound treatment 276.4 91.0 0.47 282.4 96.2 0.5 0.6893 0.9997 1975343 ChemDiv1_010925 CCN1C/C(=C\c2ccccc2C)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccccc4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A14 compound treatment 276.8 91.4 0.48 279.1 92.9 0.48 0.6787 1.0 1975344 ChemDiv1_010926 CC(=O)N/C(=C\c1ccc(F)cc1)/C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A15 compound treatment 279.4 94.0 0.49 281.4 95.2 0.49 0.6967 1.0 1631491 ChemDiv1_010927 CN(C)C(=O)CSc1nc2ccccc2n1C(=O)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A16 compound treatment 274.8 89.4 0.47 281.4 95.2 0.49 0.6797 0.9996 1719730 ChemDiv1_010928 CCCC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A17 compound treatment 273.8 88.4 0.46 280.5 94.3 0.49 0.6727 0.9995 1149118 ChemDiv1_010929 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A18 compound treatment 280.2 94.8 0.49 285.1 98.9 0.51 0.7133 0.9998 1975345 ChemDiv1_010930 COC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(Cl)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A19 compound treatment 280.0 94.6 0.49 280.4 94.2 0.49 0.6952 1.0 1975346 ChemDiv1_010931 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A20 compound treatment 275.0 89.6 0.47 281.0 94.8 0.49 0.679 0.9996 1975347 ChemDiv1_010932 COCCOC(=O)C1=C(COC)OC(=C(C(=O)OC)C21C(=O)Nc3ccccc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A21 compound treatment 275.7 90.3 0.47 281.4 95.2 0.49 0.6831 0.9997 1975348 ChemDiv1_010933 CN1CCN(CC1)C(=O)CSc2nc(cc(c2C#N)c3ccccc3)c4ccccc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A22 compound treatment 281.1 95.7 0.5 283.3 97.1 0.5 0.71 1.0 1975349 ChemDiv1_010934 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3cccc(c3)C(F)(F)F)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A23 mock treatment 278.3 92.9 0.48 280.4 94.2 0.49 0.689 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 A24 mock treatment 74.0 -111.0 -0.58 81.7 -104.0 -0.54 -0.795 -0.9994 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B01 compound treatment 286.1 101.0 0.53 286.8 101.0 0.52 0.7413 1.0 1975350 ChemDiv1_010935 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B02 compound treatment 283.0 97.6 0.51 293.4 107.0 0.56 0.7541 0.999 1975351 ChemDiv1_010936 COc1cccc(c1)C(=O)N2N=C(CC2(O)c3cccnc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B03 compound treatment 280.7 95.3 0.5 286.3 100.0 0.52 0.7195 0.9997 1975352 ChemDiv1_010937 COCC1=C(C(C(=C(N)O1)C#N)c2c(F)cccc2Cl)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B04 compound treatment 275.5 90.1 0.47 283.5 97.3 0.51 0.69 0.9993 1497707 ChemDiv1_010938 Fc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B05 compound treatment 279.0 93.6 0.49 281.8 95.6 0.5 0.6967 1.0 1288353 ChemDiv1_010939 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(C)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B06 compound treatment 278.0 92.6 0.48 286.6 100.0 0.52 0.7107 0.9993 1501442 ChemDiv1_010940 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(SC)cc3)C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B07 compound treatment 276.3 90.9 0.47 284.5 98.3 0.51 0.6967 0.9993 1609666 ChemDiv1_010941 COc1cc(ccc1OCC(=O)OC(C)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B08 compound treatment 275.2 89.8 0.47 285.4 99.2 0.52 0.6959 0.9988 1975353 ChemDiv1_010942 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3cccnc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B09 compound treatment 276.4 91.0 0.47 285.2 99.0 0.51 0.6996 0.9992 1975354 ChemDiv1_010943 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)N(C4CCCCC4)C5CCCCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B10 compound treatment 279.0 93.6 0.49 283.9 97.7 0.51 0.7044 0.9998 1498038 ChemDiv1_010944 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC=C)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B11 compound treatment 274.4 89.0 0.46 280.8 94.6 0.49 0.6761 0.9996 1550112 ChemDiv1_010945 Cc1ccc(C)c(Nc2nc3nonc3nc2N4CCCCC4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B12 compound treatment 274.6 89.2 0.47 282.7 96.5 0.5 0.6838 0.9993 1975355 ChemDiv1_010946 Cc1ccc(cc1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OCc4ccccc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B13 compound treatment 275.3 89.9 0.47 282.5 96.3 0.5 0.6856 0.9995 1975356 ChemDiv1_010947 [O-][N+](=O)c1ccc(cc1)N2N=C(/C(=C/Nc3cccc(F)c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B14 compound treatment 274.2 88.8 0.46 281.9 95.7 0.5 0.6794 0.9994 1145932 ChemDiv1_010948 Nc1c(oc2ccccc12)C(=O)c3ccc(Oc4ccccc4)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B15 compound treatment 278.1 92.7 0.48 285.6 99.4 0.52 0.7073 0.9995 1923822 ChemDiv1_010949 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccccn2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B16 compound treatment 274.1 88.7 0.46 281.4 95.2 0.49 0.6772 0.9994 1315222 ChemDiv1_010950 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc5OCOc5cc4Cl)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B17 compound treatment 275.1 89.7 0.47 284.5 98.3 0.51 0.6922 0.999 1975357 ChemDiv1_010951 COc1ccc(Nc2nc(NCc3cccnc3)nc(NCc4cccnc4)n2)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B18 compound treatment 274.6 89.2 0.47 278.6 92.4 0.48 0.6687 0.9999 1975358 ChemDiv1_010952 [O-][N+](=O)c1ccc(Nc2nc(Cl)nc(NCc3ccco3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B19 compound treatment 276.4 91.0 0.47 278.4 92.2 0.48 0.6746 1.0 1678233 ChemDiv1_010953 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC(=O)N5CCOCC5)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B20 compound treatment 272.7 87.3 0.46 280.7 94.5 0.49 0.6694 0.9993 1975359 ChemDiv1_010954 Nn1cnn2c(SCC(=O)Nc3nnc(SCC(=O)Nc4ccc(cc4)S(=O)(=O)N)s3)nnc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B21 compound treatment 281.8 96.4 0.5 279.2 93.0 0.48 0.6975 0.9998 1714590 ChemDiv1_010955 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(cc3)S(=O)(=O)N)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B22 compound treatment 277.1 91.7 0.48 276.8 90.6 0.47 0.6713 1.0 1975360 ChemDiv1_010956 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5cccc6ccccc56 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B23 mock treatment 281.0 95.6 0.5 278.2 92.0 0.48 0.6908 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 B24 mock treatment 76.6 -109.0 -0.57 79.3 -107.0 -0.56 -0.7942 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C01 compound treatment 290.7 105.0 0.55 288.7 103.0 0.53 0.7652 0.9999 1975361 ChemDiv1_010957 [O-][N+](=O)c1ccccc1NC(=O)CSc2nc(ccc2C#N)c3ccncc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C02 compound treatment 281.3 95.9 0.5 283.1 96.9 0.5 0.71 1.0 1975362 ChemDiv1_010958 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CC(NC(=O)C(F)(F)F)c3ccccc3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C03 compound treatment 261.3 75.9 0.4 266.9 80.7 0.42 0.5766 0.9996 1975363 ChemDiv1_010959 CC(=O)C1=C(C)OC(=C(C#N)C1c2ccsc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C04 compound treatment 286.0 101.0 0.52 286.5 100.0 0.52 0.7398 1.0 1975364 ChemDiv1_010960 Nc1nc(SCC(=O)Nc2ccccc2Br)c(C#N)cc1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C05 compound treatment 277.7 92.3 0.48 280.3 94.1 0.49 0.6864 1.0 1975365 ChemDiv1_010961 CCOC(=O)CC1=C(C(C(=C(N)O1)C#N)c2ccc(cc2)[N+](=O)[O-])C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C06 compound treatment 281.8 96.4 0.5 287.7 102.0 0.53 0.7287 0.9997 1975366 ChemDiv1_010962 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C07 compound treatment 278.7 93.3 0.49 285.1 98.9 0.51 0.7077 0.9996 1355436 ChemDiv1_010963 COc1ccc(NC(=O)CSc2nc3CCCCc3cc2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C08 compound treatment 282.3 96.9 0.51 286.7 101.0 0.52 0.7269 0.9999 1723941 ChemDiv1_010964 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(C)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C09 compound treatment 280.1 94.7 0.49 291.1 105.0 0.55 0.7349 0.9988 1548828 ChemDiv1_010965 CCOC(=O)c1c2CN(CCn2c3cc(Br)c(OC)cc13)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C10 compound treatment 284.3 98.9 0.52 290.8 105.0 0.54 0.7493 0.9997 1975367 ChemDiv1_010966 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C11 compound treatment 279.5 94.1 0.49 287.4 101.0 0.53 0.7191 0.9994 1975368 ChemDiv1_010967 ClCC(=O)Nc1ccc(cc1)c2nc(c3ccccc3)c4cc(NC(=O)CCl)ccc4n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C12 compound treatment 280.0 94.6 0.49 288.2 102.0 0.53 0.7239 0.9994 1925844 ChemDiv1_010968 CCOC(=O)c1ccc2nc(NC(=O)CSCC(=O)OCC(=O)c3ccc(Br)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C13 compound treatment 274.8 89.4 0.47 282.5 96.3 0.5 0.6838 0.9994 1975369 ChemDiv1_010969 COC(=O)C1=C(N)OC2=C(C1c3ccccc3F)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C14 compound treatment 276.2 90.8 0.47 284.6 98.4 0.51 0.6967 0.9993 1778165 ChemDiv1_010970 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2c(C)cc(C)c([N+](=O)[O-])c2C)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C15 compound treatment 276.3 90.9 0.47 279.9 93.7 0.49 0.6798 0.9999 1618465 ChemDiv1_010971 Cc1c(Nc2nc3nonc3nc2Nc4ccccc4C)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C16 compound treatment 273.7 88.3 0.46 283.3 97.1 0.5 0.6827 0.999 1140658 ChemDiv1_010972 CCCC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C17 compound treatment 274.6 89.2 0.47 282.7 96.5 0.5 0.6838 0.9993 1590324 ChemDiv1_010973 Oc1ccc(Nc2nc3nonc3nc2Nc4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C18 compound treatment 277.2 91.8 0.48 280.7 94.5 0.49 0.686 0.9999 1975370 ChemDiv1_010974 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(c2)C(F)(F)F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C19 compound treatment 278.5 93.1 0.49 282.6 96.4 0.5 0.6978 0.9999 1975371 ChemDiv1_010975 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C20 compound treatment 276.5 91.1 0.48 279.7 93.5 0.49 0.6798 0.9999 1975372 ChemDiv1_010976 COCC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C21 compound treatment 275.6 90.2 0.47 276.6 90.4 0.47 0.665 1.0 1504116 ChemDiv1_010977 COc1ccc(cc1)c2cc(c(C#N)c(SCC(=O)N3CCN(C)CC3)n2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C22 compound treatment 271.8 86.4 0.45 276.4 90.2 0.47 0.6503 0.9998 1354184 ChemDiv1_010978 CC(C)(C)Nc1nc(NCc2cccnc2)nc(n1)N3CCOCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C23 mock treatment 276.4 91.0 0.47 280.2 94.0 0.49 0.6812 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 C24 mock treatment 72.2 -113.0 -0.59 77.6 -109.0 -0.56 -0.8167 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D01 compound treatment 284.3 98.9 0.52 286.3 100.0 0.52 0.7328 1.0 1165431 ChemDiv1_010979 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Oc4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D02 compound treatment 281.3 95.9 0.5 286.0 99.8 0.52 0.7206 0.9998 1975373 ChemDiv1_010980 Oc1ccccc1C(=O)N2N=C(CC2(O)c3ccncc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D03 compound treatment 271.3 85.9 0.45 278.7 92.5 0.48 0.6569 0.9994 1975374 ChemDiv1_010981 COCC1=C(C(C(=C(N)O1)C#N)c2ccsc2)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D04 compound treatment 279.0 93.6 0.49 285.8 99.6 0.52 0.7114 0.9996 1668393 ChemDiv1_010982 Brc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc5ccccc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D05 compound treatment 276.9 91.5 0.48 287.8 102.0 0.53 0.711 0.9987 1228992 ChemDiv1_010983 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(C)c4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D06 compound treatment 285.0 99.6 0.52 298.6 112.0 0.58 0.7806 0.9983 1526254 ChemDiv1_010984 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc4OCOc4c3)C(=O)CCC2)c5ccc(Br)cn5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D07 compound treatment 275.7 90.3 0.47 283.0 96.8 0.5 0.6889 0.9995 1148713 ChemDiv1_010985 COc1cc(ccc1OCC=C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D08 compound treatment 274.6 89.2 0.47 289.9 104.0 0.54 0.7102 0.9973 1975375 ChemDiv1_010986 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D09 compound treatment 277.4 92.0 0.48 286.5 100.0 0.52 0.7081 0.9991 1288977 ChemDiv1_010987 Clc1nc(NCCN2CCOCC2)nc(n1)N3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D10 compound treatment 276.4 91.0 0.47 283.9 97.7 0.51 0.6948 0.9994 1385896 ChemDiv1_010988 CC(=O)OC(OC(=O)C)C1(OC2C=C1)C3C2C(=O)N(C3=O)c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D11 compound treatment 275.4 90.0 0.47 279.4 93.2 0.48 0.6746 0.9999 1631197 ChemDiv1_010989 Cc1c(Nc2nc3nonc3nc2Nc4ccc(F)cc4)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D12 compound treatment 276.9 91.5 0.48 289.5 103.0 0.54 0.7173 0.9983 1181555 ChemDiv1_010990 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc4OCOc4c3)C(=O)CCC2)c5ccc(cc5)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D13 compound treatment 284.9 99.5 0.52 288.4 102.0 0.53 0.7427 0.9999 1975376 ChemDiv1_010991 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cc(Br)cs3)N)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D14 compound treatment 243.8 58.4 0.3 252.8 66.6 0.35 0.4603 0.998 1975377 ChemDiv1_010992 O=C/1N(/C(=N/c2ccccc2)/S\C1=C/c3ccccn3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D15 compound treatment 274.1 88.7 0.46 284.7 98.5 0.51 0.6893 0.9987 1663544 ChemDiv1_010993 CC(=O)Nc1ccc2nc(SCc3ccc(Br)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D16 compound treatment 274.7 89.3 0.47 285.3 99.1 0.52 0.6937 0.9987 1575648 ChemDiv1_010994 CCc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D17 compound treatment 275.1 89.7 0.47 284.8 98.6 0.51 0.6933 0.999 1671575 ChemDiv1_010995 CC1CCN(CC1)c2nc(Cl)nc(NCCN3CCOCC3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D18 compound treatment 272.7 87.3 0.46 284.3 98.1 0.51 0.6827 0.9984 1975378 ChemDiv1_010996 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)CCc4ccccc4)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D19 compound treatment 270.6 85.2 0.44 278.8 92.6 0.48 0.6547 0.9992 1975379 ChemDiv1_010997 COc1ccc2[nH]c(Sc3ccc(cc3[N+](=O)[O-])C(F)(F)F)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D20 compound treatment 273.4 88.0 0.46 283.8 97.6 0.51 0.6834 0.9988 1191511 ChemDiv1_010998 Oc1ccc(Nc2nc(Cl)nc(NCc3ccco3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D21 compound treatment 277.9 92.5 0.48 282.1 95.9 0.5 0.6937 0.9999 1975380 ChemDiv1_010999 COc1cccc(c1)C(=O)N2N=C(CC2(O)c3ccncc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D22 compound treatment 275.7 90.3 0.47 275.5 89.3 0.46 0.6614 1.0 1217860 ChemDiv1_011000 CCOC(=O)C1=C(N)N(C2=C(C1c3cccnc3)C(=O)CC(C)(C)C2)c4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D23 mock treatment 277.3 91.9 0.48 274.6 88.4 0.46 0.664 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 D24 mock treatment 80.5 -105.0 -0.55 80.2 -106.0 -0.55 -0.7765 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E01 compound treatment 285.1 99.7 0.52 282.0 95.8 0.5 0.7199 0.9998 1617339 ChemDiv1_011001 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc3OCOc3c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E02 compound treatment 286.1 101.0 0.53 286.4 100.0 0.52 0.7398 1.0 1930952 ChemDiv1_011002 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(NC(=O)c3ccc(Br)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E03 compound treatment 279.2 93.8 0.49 284.0 97.8 0.51 0.7055 0.9998 1975381 ChemDiv1_011003 ClCCc1ccc(cc1)S(=O)(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E04 compound treatment 283.7 98.3 0.51 292.7 107.0 0.55 0.7541 0.9993 1975382 ChemDiv1_011004 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3ccccc3Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E05 compound treatment 281.2 95.8 0.5 288.3 102.0 0.53 0.7287 0.9995 1975383 ChemDiv1_011005 ClC1=CC2C3C(C1c4ccccc24)C(=O)N(C3=O)c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E06 compound treatment 280.3 94.9 0.5 281.9 95.7 0.5 0.7019 1.0 1783887 ChemDiv1_011006 COc1ccc(CCNC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-])cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E07 compound treatment 279.1 93.7 0.49 287.3 101.0 0.53 0.7173 0.9993 1695816 ChemDiv1_011007 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3[nH]2)sc4CCCc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E08 compound treatment 281.5 96.1 0.5 290.0 104.0 0.54 0.7361 0.9993 1975384 ChemDiv1_011008 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Cl)cc3)c4cc(Br)cs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E09 compound treatment 276.8 91.4 0.48 286.4 100.0 0.52 0.7055 0.999 1975385 ChemDiv1_011009 CC(C)(COC(=O)c1ccc(Br)cc1)NC2=NS(=O)(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E10 compound treatment 272.2 86.8 0.45 283.7 97.5 0.51 0.6786 0.9984 1975386 ChemDiv1_011010 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E11 compound treatment 257.8 72.4 0.38 268.7 82.5 0.43 0.5704 0.998 1975387 ChemDiv1_011011 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2[N+](=O)[O-])n3nnc(n3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E12 compound treatment 276.3 90.9 0.47 282.4 96.2 0.5 0.6889 0.9996 1975388 ChemDiv1_011012 CCNc1nc(OC)nc(n1)N2CC(=O)N(CC(=O)OCC)C2=N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E13 compound treatment 282.3 96.9 0.51 287.1 101.0 0.52 0.7284 0.9998 1975389 ChemDiv1_011013 COC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CC(C)(C)C2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E14 compound treatment 278.4 93.0 0.49 284.3 98.1 0.51 0.7037 0.9997 1597798 ChemDiv1_011014 CCOC(=O)c1c(CSc2nc(C)c(CC=C)c(C)c2C#N)n(C)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E15 compound treatment 274.4 89.0 0.46 282.0 95.8 0.5 0.6805 0.9994 1975390 ChemDiv1_011015 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5cccc(c5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E16 compound treatment 276.0 90.6 0.47 280.2 94.0 0.49 0.6798 0.9999 1246881 ChemDiv1_011016 CCCC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E17 compound treatment 276.4 91.0 0.47 286.3 100.0 0.52 0.7037 0.9989 1975391 ChemDiv1_011017 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E18 compound treatment 275.3 89.9 0.47 279.7 93.5 0.49 0.6753 0.9998 1191298 ChemDiv1_011018 Fc1cccc(c1)c2cc(nc(SCC(=O)Nc3nc4ccccc4o3)c2C#N)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E19 compound treatment 279.6 94.2 0.49 288.3 102.0 0.53 0.7228 0.9993 1975392 ChemDiv1_011019 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccnc3)N)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E20 compound treatment 273.8 88.4 0.46 282.2 96.0 0.5 0.679 0.9992 1975393 ChemDiv1_011020 CCOC(=O)C1=C(N)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E21 compound treatment 277.0 91.6 0.48 275.5 89.3 0.46 0.6662 0.9999 1975394 ChemDiv1_011021 CC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(cc32)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E22 compound treatment 276.6 91.2 0.48 279.5 93.3 0.49 0.6794 1.0 1975395 ChemDiv1_011022 CC1SC2(N(C1=O)c3ccc(Cl)cc3)C(=O)Nc4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E23 mock treatment 277.6 92.2 0.48 279.5 93.3 0.49 0.6831 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 E24 mock treatment 77.1 -108.0 -0.56 80.4 -106.0 -0.55 -0.7883 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F01 compound treatment 285.5 100.0 0.52 286.4 100.0 0.52 0.7376 1.0 1975396 ChemDiv1_011023 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F02 compound treatment 288.5 103.0 0.54 291.6 105.0 0.55 0.7678 1.0 1975397 ChemDiv1_011024 OC1(CC(=NN1C(=O)c2ccccc2F)C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F03 compound treatment 285.2 99.8 0.52 291.1 105.0 0.55 0.7538 0.9997 1975398 ChemDiv1_011025 COCC1=C(C(C(=C(N)O1)C#N)c2cccc(Br)c2)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F04 compound treatment 286.0 101.0 0.52 287.9 102.0 0.53 0.7449 1.0 1975399 ChemDiv1_011026 CCC(C)c1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F05 compound treatment 278.5 93.1 0.49 286.7 101.0 0.52 0.7129 0.9993 1975400 ChemDiv1_011027 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C(=C\c3ccc(F)cc3)/NC(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F06 compound treatment 280.5 95.1 0.5 287.4 101.0 0.53 0.7228 0.9996 1475795 ChemDiv1_011028 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccc(F)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F07 compound treatment 273.6 88.2 0.46 290.8 105.0 0.54 0.7099 0.9965 1975401 ChemDiv1_011029 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F08 compound treatment 280.4 95.0 0.5 296.7 111.0 0.57 0.7566 0.9973 1975402 ChemDiv1_011030 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4C)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F09 compound treatment 278.0 92.6 0.48 285.1 98.9 0.51 0.7051 0.9995 1975403 ChemDiv1_011031 Nc1nnc(SCC(=O)Nc2cc(cc(NC(=O)CSc3nnc(N)s3)c2Cl)C(F)(F)F)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F10 compound treatment 276.5 91.1 0.48 286.1 99.9 0.52 0.7033 0.999 1280237 ChemDiv1_011032 COc1cc(ccc1OCC(=O)OCc2ccccc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F11 compound treatment 276.8 91.4 0.48 285.2 99.0 0.51 0.7011 0.9993 1975404 ChemDiv1_011033 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)CN2C(=O)c3ccc4CCc5ccc(C2=O)c3c45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F12 compound treatment 278.4 93.0 0.49 290.3 104.0 0.54 0.7257 0.9985 1975405 ChemDiv1_011034 Nc1nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)c(C#N)cc1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F13 compound treatment 279.1 93.7 0.49 282.4 96.2 0.5 0.6993 0.9999 1975406 ChemDiv1_011035 Cn1nccc1C(=O)Nc2cc(Sc3nc4ccccc4s3)cc(c2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F14 compound treatment 281.5 96.1 0.5 290.2 104.0 0.54 0.7368 0.9993 1527070 ChemDiv1_011036 Brc1cccc(c1)C2Nc3ccccc3C(=O)N2c4ccc(I)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F15 compound treatment 277.2 91.8 0.48 285.7 99.5 0.52 0.7044 0.9993 1975407 ChemDiv1_011037 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)NCCCCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F16 compound treatment 277.2 91.8 0.48 285.4 99.2 0.52 0.7033 0.9993 1422453 ChemDiv1_011038 Brc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F17 compound treatment 276.3 90.9 0.47 286.0 99.8 0.52 0.7022 0.999 1975408 ChemDiv1_011039 COc1cccc(c1)C(=O)N2N=C(CC2(O)c3cccc(OC)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F18 compound treatment 275.5 90.1 0.47 284.6 98.4 0.51 0.6941 0.9991 1975409 ChemDiv1_011040 CN1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F19 compound treatment 273.8 88.4 0.46 281.5 95.3 0.5 0.6764 0.9994 1742967 ChemDiv1_011041 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F20 compound treatment 281.9 96.5 0.5 285.4 99.2 0.52 0.7206 0.9999 1281555 ChemDiv1_011042 C(Nc1nc(Nc2ccccc2)nc(Nc3ccccc3)n1)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F21 compound treatment 296.6 111.0 0.58 301.2 115.0 0.6 0.8329 0.9999 1975410 ChemDiv1_011043 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(F)cc3)c4cc(Br)cs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F22 compound treatment 276.1 90.7 0.47 276.7 90.5 0.47 0.6673 1.0 1975411 ChemDiv1_011044 CCOC(=O)c1nnn(c1CSc2nc3ccccc3[nH]2)c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F23 mock treatment 277.6 92.2 0.48 277.7 91.5 0.48 0.6765 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 F24 mock treatment 80.3 -105.0 -0.55 80.6 -106.0 -0.55 -0.7758 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G01 compound treatment 286.4 101.0 0.53 285.6 99.4 0.52 0.738 1.0 1975412 ChemDiv1_011045 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(C)cc(c2)N(CCCl)CCCl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G02 compound treatment 284.2 98.8 0.52 288.0 102.0 0.53 0.7387 0.9999 1975413 ChemDiv1_011046 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G03 compound treatment 287.9 103.0 0.53 285.0 98.8 0.51 0.7413 0.9998 1975414 ChemDiv1_011047 Oc1ccccc1/C=C\2/SC(=O)N(CNc3cccc(Br)c3)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G04 compound treatment 277.5 92.1 0.48 285.3 99.1 0.52 0.704 0.9994 1975415 ChemDiv1_011048 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G05 compound treatment 280.8 95.4 0.5 285.8 99.6 0.52 0.718 0.9998 1975416 ChemDiv1_011049 COc1ccc(/C=C/2\N=C(OC2=O)c3cc(ccc3Cl)[N+](=O)[O-])cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G06 compound treatment 275.0 89.6 0.47 284.4 98.2 0.51 0.6915 0.999 1616634 ChemDiv1_011050 CCOC(=O)c1c(CNc2ccccc2C(=O)N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G07 compound treatment 279.6 94.2 0.49 285.2 99.0 0.51 0.7114 0.9997 1197451 ChemDiv1_011051 COc1ccc(N(CC(=O)Nc2cccc(Br)c2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G08 compound treatment 276.5 91.1 0.48 286.4 100.0 0.52 0.7044 0.999 1975417 ChemDiv1_011052 Cc1ccc(/C=C/2\N=C(OC2=O)c3ccc(cc3)C4=N/C(=C\c5ccc(C)o5)/C(=O)O4)o1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G09 compound treatment 275.4 90.0 0.47 288.3 102.0 0.53 0.7073 0.9981 1126309 ChemDiv1_011053 CC(=O)Nc1cc(O)nc(NC(=O)C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G10 compound treatment 275.3 89.9 0.47 284.7 98.5 0.51 0.6937 0.999 1975418 ChemDiv1_011054 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccc(c3)[N+](=O)[O-])N)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G11 compound treatment 276.7 91.3 0.48 285.8 99.6 0.52 0.7029 0.9991 1354908 ChemDiv1_011055 Nn1cnn2c(SCC(=O)N3CCN(CC3)C(=O)CSc4nnc5n(N)cnn45)nnc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G12 compound treatment 275.5 90.1 0.47 286.8 101.0 0.52 0.7022 0.9986 1137142 ChemDiv1_011056 CCN(CC)c1nc2nonc2nc1N(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G13 compound treatment 274.3 88.9 0.46 284.4 98.2 0.51 0.6889 0.9989 1212612 ChemDiv1_011057 CCOC(=O)COc1ccc2ccccc2c1C3NC(=O)NC(=C3C(=O)OCC)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G14 compound treatment 279.5 94.1 0.49 286.8 101.0 0.52 0.7169 0.9995 1657104 ChemDiv1_011058 CC(=O)Oc1c(Cl)cc(cc1Cl)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G15 compound treatment 274.1 88.7 0.46 282.7 96.5 0.5 0.6819 0.9992 1975419 ChemDiv1_011059 FC(F)(F)c1cccc(c1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G16 compound treatment 274.1 88.7 0.46 282.8 96.6 0.5 0.6823 0.9992 1975420 ChemDiv1_011060 COCCOC(=O)C1=C(C)OC(=C(C(=O)OC(C)C)C21C(=O)Nc3ccccc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G17 compound treatment 281.4 96.0 0.5 284.4 98.2 0.51 0.7151 1.0 1358220 ChemDiv1_011061 CCOC(=O)c1c2CN(Cc3ccccc3)CCn2c4cc(Br)c(OC)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G18 compound treatment 279.1 93.7 0.49 282.1 95.9 0.5 0.6982 1.0 1975421 ChemDiv1_011062 CC1=C(C(C(=C(N)O1)C#N)c2ccc(F)cc2F)C(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G19 compound treatment 277.7 92.3 0.48 284.9 98.7 0.51 0.7033 0.9995 1639893 ChemDiv1_011063 Cc1cc2OC(=C(C(=O)OCc3ccccc3)C4(C(=O)Nc5ccccc54)c2c(=O)o1)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G20 compound treatment 276.9 91.5 0.48 276.8 90.6 0.47 0.6706 1.0 1975422 ChemDiv1_011064 COCCOC(=O)C1=C(C)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G21 compound treatment 274.5 89.1 0.46 278.9 92.7 0.48 0.6694 0.9998 1975423 ChemDiv1_011065 CC1=C(C(=O)OCC=C)C2(C(=O)Nc3ccc(cc32)[N+](=O)[O-])C(=C(N)O1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G22 compound treatment 273.6 88.2 0.46 280.1 93.9 0.49 0.6705 0.9996 1719857 ChemDiv1_011066 O=C1CSC(N1c2ccc(cc2)N3C(SCC3=O)c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G23 mock treatment 278.2 92.8 0.48 277.6 91.4 0.48 0.6783 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 G24 mock treatment 65.0 -120.0 -0.63 79.9 -106.0 -0.55 -0.8348 -0.998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H01 compound treatment 388.7 203.0 1.06 381.8 196.0 1.02 1.4689 0.9998 1187282 ChemDiv1_011067 CC(=O)OCc1c(C)ccc(C2C(=C(N)OC(=C2C#N)N)C#N)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H02 compound treatment 280.2 94.8 0.49 281.0 94.8 0.49 0.6982 1.0 1975424 ChemDiv1_011068 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3ccccc3[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H03 compound treatment 281.4 96.0 0.5 283.2 97.0 0.5 0.7107 1.0 1975425 ChemDiv1_011069 COc1cccc(c1)c2cc(c(C#N)c(SCC(=O)NC3CC3)n2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H04 compound treatment 278.9 93.5 0.49 287.5 101.0 0.53 0.7173 0.9993 1463275 ChemDiv1_011070 Clc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H05 compound treatment 283.3 97.9 0.51 293.1 107.0 0.56 0.7541 0.9991 1975426 ChemDiv1_011071 COc1cc(C=c2sc3nc4ccccc4n3c2=O)c(cc1OCc5ccccc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H06 compound treatment 282.1 96.7 0.5 292.8 107.0 0.55 0.7486 0.9989 1975427 ChemDiv1_011072 O=C(CSc1nc2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2s1)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H07 compound treatment 277.1 91.7 0.48 285.0 98.8 0.51 0.7015 0.9994 1282764 ChemDiv1_011073 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccccc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H08 compound treatment 277.4 92.0 0.48 283.3 97.1 0.5 0.6963 0.9997 1780068 ChemDiv1_011074 CCSc1nc2ccccc2n1Cc3ccc(OC)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H09 compound treatment 280.0 94.6 0.49 285.9 99.7 0.52 0.7155 0.9997 1975428 ChemDiv1_011075 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4ccccc4C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H10 compound treatment 275.6 90.2 0.47 288.8 103.0 0.53 0.7099 0.998 1371416 ChemDiv1_011076 CCCCc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H11 compound treatment 275.1 89.7 0.47 286.8 101.0 0.52 0.7007 0.9985 1975429 ChemDiv1_011077 COc1cccc(c1)C2(O)CC(=NN2C(=O)Cc3ccccc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H12 compound treatment 274.0 88.6 0.46 288.6 102.0 0.53 0.7033 0.9975 1975430 ChemDiv1_011078 COc1cc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(Br)cc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H13 compound treatment 278.9 93.5 0.49 286.7 101.0 0.52 0.7143 0.9994 1975431 ChemDiv1_011079 CCN(CC)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H14 compound treatment 276.0 90.6 0.47 285.3 99.1 0.52 0.6985 0.9991 1975432 ChemDiv1_011080 CCOC(=O)c1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H15 compound treatment 282.5 97.1 0.51 286.3 100.0 0.52 0.7262 0.9999 1207201 ChemDiv1_011081 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3C)n(c4ccccc4)c5cc(Br)c(OC)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H16 compound treatment 277.7 92.3 0.48 282.2 96.0 0.5 0.6934 0.9998 1538222 ChemDiv1_011082 Cc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H17 compound treatment 277.7 92.3 0.48 283.3 97.1 0.5 0.6974 0.9997 1975433 ChemDiv1_011083 OC1(CC(=NN1C(=O)c2ccccc2F)C(F)(F)F)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H18 compound treatment 276.8 91.4 0.48 285.4 99.2 0.52 0.7018 0.9992 1453435 ChemDiv1_011084 CCOC(=O)c1ccc2nc(NC(=O)COC(=O)c3ccc(cc3)N4C(=O)CCC4=O)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H19 compound treatment 276.3 90.9 0.47 280.2 94.0 0.49 0.6809 0.9999 1655986 ChemDiv1_011085 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CCC2)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H20 compound treatment 278.7 93.3 0.49 281.6 95.4 0.5 0.6949 1.0 1975434 ChemDiv1_011086 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3cccc(OC)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H21 compound treatment 273.0 87.6 0.46 277.7 91.5 0.48 0.6595 0.9998 1779030 ChemDiv1_011087 Cc1cccc(Nc2nc3nonc3nc2N4CCC(Cc5ccccc5)CC4)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H22 compound treatment 278.7 93.3 0.49 278.8 92.6 0.48 0.6846 1.0 1684809 ChemDiv1_011088 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H23 mock treatment 277.0 91.6 0.48 279.1 92.9 0.48 0.6794 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 H24 mock treatment 80.0 -105.0 -0.55 76.2 -110.0 -0.57 -0.793 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I01 compound treatment 282.1 96.7 0.5 287.7 102.0 0.53 0.7298 0.9997 1975435 ChemDiv1_011089 CC/1=NN(C(=O)\C1=C/Nc2ccc([N+](=O)[O-])c(c2)[N+](=O)[O-])c3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I02 compound treatment 283.6 98.2 0.51 284.2 98.0 0.51 0.7225 1.0 1975436 ChemDiv1_011090 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I03 compound treatment 257.2 71.8 0.37 265.1 78.9 0.41 0.5549 0.999 1975437 ChemDiv1_011091 COc1cc(cc(OC)c1OC)C2C(=C(N)OC(=C2C(=O)C)C)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I04 compound treatment 280.7 95.3 0.5 284.2 98.0 0.51 0.7118 0.9999 1402704 ChemDiv1_011092 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(OC)cc2OC)S(=O)(=O)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I05 compound treatment 282.5 97.1 0.51 283.7 97.5 0.51 0.7166 1.0 1275934 ChemDiv1_011093 COC(=O)COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I06 compound treatment 281.1 95.7 0.5 286.3 100.0 0.52 0.721 0.9998 1291053 ChemDiv1_011094 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(OC)c(OC)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I07 compound treatment 280.6 95.2 0.5 287.4 101.0 0.53 0.7232 0.9996 1975438 ChemDiv1_011095 FC(F)(F)c1cccc(c1)N(CC(=O)Nc2cccc(Br)c2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I08 compound treatment 279.2 93.8 0.49 285.3 99.1 0.52 0.7103 0.9997 1975439 ChemDiv1_011096 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I09 compound treatment 277.0 91.6 0.48 288.7 103.0 0.53 0.7147 0.9985 1296016 ChemDiv1_011097 NNC(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I10 compound treatment 283.5 98.1 0.51 291.1 105.0 0.55 0.7475 0.9995 1975440 ChemDiv1_011098 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cc(Br)cs3)N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I11 compound treatment 281.7 96.3 0.5 296.4 110.0 0.57 0.7603 0.9979 1975441 ChemDiv1_011099 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccn2)c1C#N)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I12 compound treatment 271.6 86.2 0.45 287.1 101.0 0.52 0.6889 0.9971 1975442 ChemDiv1_011100 COc1ccc(OC)c(c1)N(CC(=O)NCCSc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I13 compound treatment 272.6 87.2 0.45 285.5 99.3 0.52 0.6867 0.998 1975443 ChemDiv1_011101 COc1ccc(Br)cc1C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I14 compound treatment 275.1 89.7 0.47 280.6 94.4 0.49 0.6779 0.9997 1401766 ChemDiv1_011102 COC(=O)COc1ccc(cc1OC)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I15 compound treatment 277.4 92.0 0.48 285.3 99.1 0.52 0.7037 0.9994 1948034 ChemDiv1_011103 COc1ccc(cc1)C(NC2=NS(=O)(=O)c3cc(ccc23)[N+](=O)[O-])c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I16 compound treatment 275.8 90.4 0.47 282.3 96.1 0.5 0.6867 0.9996 1104610 ChemDiv1_011104 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccccc2Cl)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I17 compound treatment 263.5 78.1 0.41 271.9 85.7 0.45 0.6031 0.999 1975444 ChemDiv1_011105 CC1=C(C(C(=C(N)O1)C#N)c2cccnc2)n3nnc(n3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I18 compound treatment 277.5 92.1 0.48 279.8 93.6 0.49 0.6838 1.0 1975445 ChemDiv1_011106 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccccc4C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I19 compound treatment 276.8 91.4 0.48 283.8 97.6 0.51 0.6959 0.9995 1592099 ChemDiv1_011107 CC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I20 compound treatment 276.9 91.5 0.48 284.3 98.1 0.51 0.6981 0.9995 1975446 ChemDiv1_011108 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)C(F)(F)F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I21 compound treatment 289.1 104.0 0.54 292.4 106.0 0.55 0.7729 0.9999 1975447 ChemDiv1_011109 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)NC4CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I22 compound treatment 275.3 89.9 0.47 277.6 91.4 0.48 0.6676 1.0 1975448 ChemDiv1_011110 COc1ccc(cc1)N(CC(=O)NCCSc2ccc(Cl)cc2)S(=O)(=O)c3ccc(C)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I23 mock treatment 277.6 92.2 0.48 276.5 90.3 0.47 0.6721 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 I24 mock treatment 78.1 -107.0 -0.56 75.0 -111.0 -0.58 -0.8045 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J01 compound treatment 282.8 97.4 0.51 285.8 99.6 0.52 0.7254 1.0 1975449 ChemDiv1_011111 [O-][N+](=O)c1ccc(cc1)N2C(=O)C3C4OC(CNC(=O)COc5ccccc5)(C=C4)C3C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J02 compound treatment 282.1 96.7 0.5 287.0 101.0 0.52 0.7273 0.9998 1630350 ChemDiv1_011112 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccc(Cl)cc5)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J03 compound treatment 279.2 93.8 0.49 283.3 97.1 0.5 0.703 0.9999 1975450 ChemDiv1_011113 CCOC(=O)CC(=O)CSc1nc(cc(C)c1C#N)c2cccnc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J04 compound treatment 280.0 94.6 0.49 283.6 97.4 0.51 0.707 0.9999 1975451 ChemDiv1_011114 OCCCNc1ccc([N+](=O)[O-])c(Sc2nc3ccccc3[nH]2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J05 compound treatment 277.7 92.3 0.48 288.3 102.0 0.53 0.7158 0.9988 1975452 ChemDiv1_011115 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccccc4C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J06 compound treatment 282.8 97.4 0.51 287.0 101.0 0.52 0.7298 0.9999 1975453 ChemDiv1_011116 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc([N+](=O)[O-])c(OC)cc3OC)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J07 compound treatment 274.2 88.8 0.46 285.3 99.1 0.52 0.6919 0.9986 1975454 ChemDiv1_011117 CCOc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J08 compound treatment 292.6 107.0 0.56 296.6 110.0 0.57 0.8013 0.9999 1975455 ChemDiv1_011118 CCOc1cc(/C=C\2/SC(=S)N(C)C2=O)ccc1OC(=O)c3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J09 compound treatment 279.7 94.3 0.49 284.0 97.8 0.51 0.7074 0.9999 1975456 ChemDiv1_011119 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J10 compound treatment 277.8 92.4 0.48 283.3 97.1 0.5 0.6978 0.9997 1671883 ChemDiv1_011120 Cc1ccc(cc1Cl)N2C(Nc3ccccc3C2=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J11 compound treatment 279.1 93.7 0.49 285.7 99.5 0.52 0.7114 0.9996 1975457 ChemDiv1_011121 Cc1c(NS(=O)(=O)c2ccc3C(=O)c4ccccc4C(=O)c3c2)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J12 compound treatment 280.2 94.8 0.49 291.8 106.0 0.55 0.7379 0.9986 1975458 ChemDiv1_011122 Nc1nc(SCC(=O)c2ccc(cc2)c3ccccc3)c(C#N)cc1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J13 compound treatment 278.3 92.9 0.48 287.9 102.0 0.53 0.7165 0.9991 1975459 ChemDiv1_011123 [O-][N+](=O)c1ccc(cc1)N2N=C(/C(=C/Nc3ccc(Cl)c(Cl)c3)/C2=O)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J14 compound treatment 276.8 91.4 0.48 285.8 99.6 0.52 0.7033 0.9992 1572921 ChemDiv1_011124 CCN(CC)c1ccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(OCc5ccc(Cl)cc5)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J15 compound treatment 276.0 90.6 0.47 281.7 95.5 0.5 0.6853 0.9997 1975460 ChemDiv1_011125 [O-][N+](=O)c1ccc2nc(NC(=O)CSc3nc4ccccc4[nH]3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J16 compound treatment 276.5 91.1 0.48 283.4 97.2 0.51 0.6934 0.9995 1211342 ChemDiv1_011126 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccc(Cl)cc5Cl)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J17 compound treatment 277.5 92.1 0.48 285.2 99.0 0.51 0.7037 0.9994 1363309 ChemDiv1_011127 O=C(CSCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccccc3)sc2c1)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J18 compound treatment 280.9 95.5 0.5 283.0 96.8 0.5 0.7081 1.0 1975461 ChemDiv1_011128 [O-][N+](=O)c1ccc(Nc2nc(NCc3ccco3)nc(Nc4ccc(Cl)cc4)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J19 compound treatment 275.9 90.5 0.47 280.4 94.2 0.49 0.6801 0.9998 1975462 ChemDiv1_011129 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4C(F)(F)F)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J20 compound treatment 277.8 92.4 0.48 279.9 93.7 0.49 0.6853 1.0 1975463 ChemDiv1_011130 Nc1nc(SCC(=O)N(c2ccccc2)c3ccccc3)c(C#N)cc1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J21 compound treatment 278.4 93.0 0.49 276.3 90.1 0.47 0.6743 0.9998 1975464 ChemDiv1_011131 [O-][N+](=O)c1cc2OCOc2cc1C=C3C(=O)N(C(=S)N(C3=O)c4ccccc4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J22 compound treatment 273.8 88.4 0.46 278.7 92.5 0.48 0.6661 0.9998 1975465 ChemDiv1_011132 COC(=O)C1=C(N)N(C2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J23 mock treatment 280.7 95.3 0.5 277.5 91.3 0.47 0.6872 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 J24 mock treatment 78.8 -107.0 -0.56 81.2 -105.0 -0.55 -0.7791 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K01 compound treatment 285.4 100.0 0.52 282.1 95.9 0.5 0.7214 0.9997 1975466 ChemDiv1_011133 CC/1=NN(C(=O)\C1=C/Nc2c(Cl)cc(Cl)cc2Cl)c3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K02 compound treatment 282.0 96.6 0.5 287.0 101.0 0.52 0.7269 0.9998 1975467 ChemDiv1_011134 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K03 compound treatment 281.5 96.1 0.5 287.1 101.0 0.52 0.7254 0.9997 1975468 ChemDiv1_011135 Cc1cc(c(C#N)c(SCC(=O)Nc2ccccc2[N+](=O)[O-])n1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K04 compound treatment 277.2 91.8 0.48 288.5 102.0 0.53 0.7147 0.9986 1975469 ChemDiv1_011136 COc1ccc(OC)c(c1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K05 compound treatment 277.9 92.5 0.48 281.8 95.6 0.5 0.6926 0.9999 1975470 ChemDiv1_011137 CCCCCOc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K06 compound treatment 278.5 93.1 0.49 283.7 97.5 0.51 0.7018 0.9998 1163654 ChemDiv1_011138 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K07 compound treatment 279.9 94.5 0.49 281.7 95.5 0.5 0.6997 1.0 1491109 ChemDiv1_011139 CCOC(=O)c1c(CN2CCOCC2)n(CC(=O)OC)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K08 compound treatment 283.4 98.0 0.51 290.3 104.0 0.54 0.7442 0.9996 1482314 ChemDiv1_011140 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K09 compound treatment 277.5 92.1 0.48 285.2 99.0 0.51 0.7037 0.9994 1578834 ChemDiv1_011141 OC(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K10 compound treatment 278.7 93.3 0.49 284.0 97.8 0.51 0.7037 0.9998 1306844 ChemDiv1_011142 COc1cccc(c1)C(=O)N(C2CC(C)N(C(=O)C)c3ccccc23)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K11 compound treatment 261.4 76.0 0.4 258.5 72.3 0.38 0.5461 0.9996 1975471 ChemDiv1_011143 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)Nc4ccccn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K12 compound treatment 275.7 90.3 0.47 285.1 98.9 0.51 0.6967 0.999 1975472 ChemDiv1_011144 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CCCC3=O)c4ccc(Br)cc4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K13 compound treatment 275.2 89.8 0.47 282.3 96.1 0.5 0.6845 0.9995 1248627 ChemDiv1_011145 COc1cc(ccc1OCc2ccc(Cl)cc2Cl)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K14 compound treatment 273.1 87.7 0.46 285.7 99.5 0.52 0.6893 0.9981 1975473 ChemDiv1_011146 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(NC(=O)c3ccc(NC(=O)C(F)(F)F)cc3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K15 compound treatment 272.8 87.4 0.46 279.6 93.4 0.49 0.6657 0.9995 1267513 ChemDiv1_011147 CCOC(=O)c1oc2ccc(Cl)cc2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K16 compound treatment 278.1 92.7 0.48 285.8 99.6 0.52 0.7081 0.9994 1975474 ChemDiv1_011148 COCC1=C(C(C(=C(N)O1)C#N)c2cccc(Cl)c2)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K17 compound treatment 271.8 86.4 0.45 283.0 96.8 0.5 0.6746 0.9985 1975475 ChemDiv1_011149 CC1=C(C(C(=C(N)O1)C#N)c2cccnc2)n3cnc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K18 compound treatment 276.2 90.8 0.47 282.9 96.7 0.5 0.6904 0.9996 1975476 ChemDiv1_011150 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccccc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K19 compound treatment 276.3 90.9 0.47 285.2 99.0 0.51 0.6992 0.9992 1975477 ChemDiv1_011151 Fc1ccc(cc1)c2cc(nc(SCC(=O)NC3CC3)c2C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K20 compound treatment 277.7 92.3 0.48 280.2 94.0 0.49 0.686 1.0 1937538 ChemDiv1_011152 COc1ccc2nc(NC(=O)COC(=O)C(CCSC)NC(=O)c3ccccc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K21 compound treatment 307.3 122.0 0.64 308.4 122.0 0.64 0.8989 1.0 1975478 ChemDiv1_011153 COc1ccc(cc1OC)C(=O)CSc2nc(ccc2C#N)c3cccs3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K22 compound treatment 276.3 90.9 0.47 279.7 93.5 0.49 0.679 0.9999 1418024 ChemDiv1_011154 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OCC)cc3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K23 mock treatment 273.4 88.0 0.46 280.1 93.9 0.49 0.6698 0.9995 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 K24 mock treatment 80.2 -105.0 -0.55 80.8 -105.0 -0.55 -0.7754 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L01 compound treatment 284.9 99.5 0.52 283.2 97.0 0.5 0.7236 0.9999 1555602 ChemDiv1_011155 C(CN1CCOCC1)Nc2nc(Oc3ccccc3)nc(Oc4ccccc4)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L02 compound treatment 287.7 102.0 0.53 291.1 105.0 0.55 0.763 0.9999 1975479 ChemDiv1_011156 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4cccc(C)c4)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L03 compound treatment 285.1 99.7 0.52 289.8 104.0 0.54 0.7486 0.9998 1975480 ChemDiv1_011157 COc1ccc(cc1)C(=O)CSc2nc(cc(C)c2C#N)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L04 compound treatment 279.9 94.5 0.49 283.9 97.7 0.51 0.7077 0.9999 1975481 ChemDiv1_011158 CC(=O)OCCn1c(=O)c2ccc3c(=O)n(CCOC(=O)C)c(=O)c4ccc(c1=O)c2c34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L05 compound treatment 275.0 89.6 0.47 283.8 97.6 0.51 0.6893 0.9992 1164182 ChemDiv1_011159 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(C)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L06 compound treatment 287.1 102.0 0.53 292.0 106.0 0.55 0.7641 0.9998 1975482 ChemDiv1_011160 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4cccc(c4)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L07 compound treatment 279.4 94.0 0.49 283.4 97.2 0.51 0.7041 0.9999 1975483 ChemDiv1_011161 CCOc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L08 compound treatment 276.4 91.0 0.47 286.4 100.0 0.52 0.704 0.9989 1975484 ChemDiv1_011162 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(Br)cn4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L09 compound treatment 283.1 97.7 0.51 285.7 99.5 0.52 0.7262 1.0 1975485 ChemDiv1_011163 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3cc(ccc3Cl)C(F)(F)F)c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L10 compound treatment 278.7 93.3 0.49 282.2 96.0 0.5 0.6971 0.9999 1640332 ChemDiv1_011164 Clc1ccc(cc1Cl)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L11 compound treatment 271.5 86.1 0.45 283.9 97.7 0.51 0.6768 0.9981 1617717 ChemDiv1_011165 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Cl)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L12 compound treatment 275.0 89.6 0.47 286.1 99.9 0.52 0.6978 0.9986 1567359 ChemDiv1_011166 CCN1C(=C(C(NC1=O)c2cc(Br)c(O)c(OC)c2)C(=O)OC(C)C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L13 compound treatment 276.2 90.8 0.47 282.8 96.6 0.5 0.69 0.9996 1354388 ChemDiv1_011167 Clc1ccc(cc1)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc4ccccc4c3)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L14 compound treatment 274.2 88.8 0.46 282.1 95.9 0.5 0.6801 0.9993 1975486 ChemDiv1_011168 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccc(C)cc4)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L15 compound treatment 275.6 90.2 0.47 279.9 93.7 0.49 0.6772 0.9999 1975487 ChemDiv1_011169 CC(C)(C)Nc1nc(Cl)nc(Nc2cccc(c2)[N+](=O)[O-])n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L16 compound treatment 274.6 89.2 0.47 285.3 99.1 0.52 0.6933 0.9987 1975488 ChemDiv1_011170 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4C(F)(F)F)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L17 compound treatment 274.7 89.3 0.47 279.1 92.9 0.48 0.6709 0.9998 1975489 ChemDiv1_011171 CCOC(=O)c1c(CN2CCOCC2)n(C)c3ccc(OS(=O)(=O)c4ccc(C)cc4)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L18 compound treatment 278.3 92.9 0.48 284.6 98.4 0.51 0.7044 0.9996 1361982 ChemDiv1_011172 Fc1cccc(C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5)c1F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L19 compound treatment 279.6 94.2 0.49 286.8 101.0 0.52 0.7173 0.9995 1975490 ChemDiv1_011173 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(Br)s3)C(=O)CCC2)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L20 compound treatment 277.4 92.0 0.48 278.5 92.3 0.48 0.6787 1.0 1975491 ChemDiv1_011174 OC1(CC(=NN1C(=O)c2ccccc2[N+](=O)[O-])C(F)(F)F)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L21 compound treatment 275.3 89.9 0.47 278.6 92.4 0.48 0.6713 0.9999 1169857 ChemDiv1_011175 CC1CCN(CC1)c2nc3nonc3nc2Nc4cccc(C)c4C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L22 compound treatment 273.1 87.7 0.46 274.7 88.5 0.46 0.6488 1.0 1608957 ChemDiv1_011176 Brc1ccccc1C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L23 mock treatment 277.6 92.2 0.48 277.0 90.8 0.47 0.6739 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 L24 mock treatment 78.5 -107.0 -0.56 78.3 -108.0 -0.56 -0.7909 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M01 compound treatment 282.1 96.7 0.5 294.5 108.0 0.56 0.7548 0.9985 1975492 ChemDiv1_011177 CCOc1ccc(N/C=C\2/C(=NN(C2=O)c3cccc(Cl)c3)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M02 compound treatment 286.1 101.0 0.53 289.2 103.0 0.54 0.7501 1.0 1975493 ChemDiv1_011178 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc(Br)s3)N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M03 compound treatment 276.6 91.2 0.48 281.7 95.5 0.5 0.6875 0.9998 1975494 ChemDiv1_011179 COc1ccc(N(CC(=O)NCCSc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M04 compound treatment 281.2 95.8 0.5 285.7 99.5 0.52 0.7192 0.9999 1264363 ChemDiv1_011180 COc1ccc(N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M05 compound treatment 275.7 90.3 0.47 284.1 97.9 0.51 0.693 0.9993 1975495 ChemDiv1_011181 COC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M06 compound treatment 274.8 89.4 0.47 280.4 94.2 0.49 0.6761 0.9997 1975496 ChemDiv1_011182 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(cc4)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M07 compound treatment 280.0 94.6 0.49 293.7 108.0 0.56 0.7441 0.9981 1501366 ChemDiv1_011183 CCOC(=O)c1c2CN(CCn2c3cc(Br)c(OC)cc13)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M08 compound treatment 278.9 93.5 0.49 284.7 98.5 0.51 0.707 0.9997 1975497 ChemDiv1_011184 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)C(F)(F)F)c3cccnc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M09 compound treatment 278.3 92.9 0.48 285.6 99.4 0.52 0.7081 0.9995 1490070 ChemDiv1_011185 O=C1N(CCCN2C(=O)C3(OCCO3)c4ccccc24)c5ccccc5C61OCCO6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M10 compound treatment 277.1 91.7 0.48 282.8 96.6 0.5 0.6934 0.9997 1975498 ChemDiv1_011186 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4cccc(c4)[N+](=O)[O-])N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M11 compound treatment 278.7 93.3 0.49 290.9 105.0 0.54 0.729 0.9984 1975499 ChemDiv1_011187 Cc1cccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M12 compound treatment 276.3 90.9 0.47 280.3 94.1 0.49 0.6812 0.9999 1975500 ChemDiv1_011188 CC1=NN(C(=O)c2ccccc2Br)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M13 compound treatment 277.9 92.5 0.48 284.7 98.5 0.51 0.7033 0.9996 1975501 ChemDiv1_011189 COC(=O)c1ccc2nc(NC(=O)CSCC(=O)OCC(=O)c3ccc(Br)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M14 compound treatment 275.0 89.6 0.47 280.5 94.3 0.49 0.6772 0.9997 1975502 ChemDiv1_011190 COCCOC(=O)C1=C(C)OC(=C(C(=O)OCC=C)C21C(=O)Nc3ccccc32)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M15 compound treatment 275.9 90.5 0.47 283.9 97.7 0.51 0.693 0.9993 1975503 ChemDiv1_011191 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(cc3)[N+](=O)[O-])c4ccc(Br)s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M16 compound treatment 279.4 94.0 0.49 292.0 106.0 0.55 0.7357 0.9984 1975504 ChemDiv1_011192 CC(C)OC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(Cl)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M17 compound treatment 269.6 84.2 0.44 271.1 84.9 0.44 0.6227 1.0 1593923 ChemDiv1_011193 Cc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M18 compound treatment 278.7 93.3 0.49 284.2 98.0 0.51 0.7044 0.9997 1975505 ChemDiv1_011194 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M19 compound treatment 273.1 87.7 0.46 281.5 95.3 0.5 0.6738 0.9992 1681847 ChemDiv1_011195 COc1ccc(cc1)c2cc(nc3sc(C(=O)NC4CC4)c(N)c23)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M20 compound treatment 274.2 88.8 0.46 277.1 90.9 0.47 0.6617 1.0 1975506 ChemDiv1_011196 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(NC(=O)CCCOc3ccc(Cl)cc3Cl)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M21 compound treatment 279.8 94.4 0.49 282.1 95.9 0.5 0.7008 1.0 1975507 ChemDiv1_011197 Nc1nc(SCC(=O)NCc2ccccc2)c(C#N)c(c1C#N)c3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M22 compound treatment 274.5 89.1 0.46 277.0 90.8 0.47 0.6625 1.0 1359155 ChemDiv1_011198 O=S(=O)(N1CCC(Cc2ccccc2)CC1)c3cccc4nsnc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M23 mock treatment 275.4 90.0 0.47 278.0 91.8 0.48 0.6695 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 M24 mock treatment 177.1 -8.3 -0.04 187.8 1.61 0.01 -0.0247 -0.5598 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N01 compound treatment 282.8 97.4 0.51 288.3 102.0 0.53 0.7346 0.9998 1272054 ChemDiv1_011199 CN(C)c1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N02 compound treatment 281.0 95.6 0.5 285.6 99.4 0.52 0.718 0.9998 1527611 ChemDiv1_011200 CCOc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(OC)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N03 compound treatment 294.1 109.0 0.57 295.6 109.0 0.57 0.8031 1.0 1463414 ChemDiv1_011201 CN1CCc2nc(SCC(=O)Oc3ccc(C)cc3)c(C#N)c(c4ccco4)c2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N04 compound treatment 282.8 97.4 0.51 280.0 93.8 0.49 0.7041 0.9998 1975508 ChemDiv1_011202 OC1(CC(=NN1C(=O)c2cccc(c2)[N+](=O)[O-])C(F)(F)F)c3ccncc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N05 compound treatment 279.5 94.1 0.49 286.2 100.0 0.52 0.7147 0.9996 1780119 ChemDiv1_011203 [O-][N+](=O)c1cccc(c1)c2csc(NC(=O)c3cc4cc(Br)ccc4oc3=O)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N06 compound treatment 282.2 96.8 0.5 282.7 96.5 0.5 0.7118 1.0 1674179 ChemDiv1_011204 Cc1ccccc1C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N07 compound treatment 275.5 90.1 0.47 283.6 97.4 0.51 0.6904 0.9993 1527151 ChemDiv1_011205 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CCCC3=O)c4cc(OC)c(OC)c(OC)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N08 compound treatment 282.6 97.2 0.51 290.1 104.0 0.54 0.7405 0.9995 1779828 ChemDiv1_011206 COc1ccc(cc1c2ccc(o2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N09 compound treatment 276.0 90.6 0.47 283.6 97.4 0.51 0.6923 0.9994 1523686 ChemDiv1_011207 Cc1c(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N10 compound treatment 279.8 94.4 0.49 283.8 97.6 0.51 0.707 0.9999 1975509 ChemDiv1_011208 COc1cc(Br)c(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N11 compound treatment 278.1 92.7 0.48 283.8 97.6 0.51 0.7007 0.9997 1561647 ChemDiv1_011209 CC(=O)n1c2ccc(F)cc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N12 compound treatment 272.8 87.4 0.46 285.5 99.3 0.52 0.6874 0.9981 1975510 ChemDiv1_011210 COc1cc(ccc1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N13 compound treatment 276.5 91.1 0.48 284.6 98.4 0.51 0.6978 0.9993 1975511 ChemDiv1_011211 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CCC2)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N14 compound treatment 273.7 88.3 0.46 283.8 97.6 0.51 0.6845 0.9988 1975512 ChemDiv1_011212 O=C/1N(/C(=N/c2ccccn2)/S\C1=C\c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N15 compound treatment 283.7 98.3 0.51 285.4 99.2 0.52 0.7273 1.0 1657006 ChemDiv1_011213 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N16 compound treatment 274.3 88.9 0.46 283.3 97.1 0.5 0.6849 0.9991 1975513 ChemDiv1_011214 COc1ccc(Nc2nc(Cl)nc(NC(C)C)n2)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N17 compound treatment 274.9 89.5 0.47 278.4 92.2 0.48 0.6691 0.9999 1202610 ChemDiv1_011215 Clc1cc(Cl)c(cc1C(=O)Oc2cccc3cccnc23)S(=O)(=O)N4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N18 compound treatment 277.1 91.7 0.48 284.9 98.7 0.51 0.7011 0.9994 1975514 ChemDiv1_011216 CCOC(=O)/C=C(\C)/N1N=C(CC1c2ccccc2)/C=C/c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N19 compound treatment 272.9 87.5 0.46 280.3 94.1 0.49 0.6687 0.9994 1975515 ChemDiv1_011217 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccccc3C(F)(F)F)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N20 compound treatment 280.3 94.9 0.5 278.5 92.3 0.48 0.6894 0.9999 1975516 ChemDiv1_011218 Cc1ccc(cc1)C2(O)CC(=NN2C(=O)c3cccc(Cl)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N21 compound treatment 274.6 89.2 0.47 279.1 92.9 0.48 0.6705 0.9998 1502768 ChemDiv1_011219 Brc1ccc(OCc2ccccc2)c(C=c3sc4nc5ccccc5n4c3=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N22 compound treatment 278.9 93.5 0.49 276.5 90.3 0.47 0.6769 0.9998 1975517 ChemDiv1_011220 COC(=O)C1=C(N)N(C2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N23 mock treatment 278.9 93.5 0.49 278.0 91.8 0.48 0.6824 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 N24 mock treatment 184.4 -0.997 -0.01 186.0 -0.188 0.0 -0.0044 -0.8253 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O01 compound treatment 285.4 100.0 0.52 283.0 96.8 0.5 0.7247 0.9998 1975518 ChemDiv1_011221 CC/1=NN(C(=O)\C1=C/Nc2ccc(I)cc2)c3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O02 compound treatment 276.4 91.0 0.47 282.5 96.3 0.5 0.6897 0.9996 1975519 ChemDiv1_011222 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O03 compound treatment 282.7 97.3 0.51 281.5 95.3 0.5 0.7092 0.9999 1975520 ChemDiv1_011223 COc1ccc(N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O04 compound treatment 279.7 94.3 0.49 284.9 98.7 0.51 0.7107 0.9998 1975521 ChemDiv1_011224 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O05 compound treatment 277.3 91.9 0.48 283.5 97.3 0.51 0.6967 0.9996 1294636 ChemDiv1_011225 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4OCc5ccc(Cl)cc5)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O06 compound treatment 277.0 91.6 0.48 284.0 97.8 0.51 0.6974 0.9995 1975522 ChemDiv1_011226 Oc1ccccc1C2(O)CC(=NN2C(=O)c3ccccc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O07 compound treatment 277.8 92.4 0.48 280.5 94.3 0.49 0.6875 1.0 1975523 ChemDiv1_011227 O=S1(=O)N=C(N(CCOc2ccccc2)CCOc3ccccc3)c4ccccc41 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O08 compound treatment 274.1 88.7 0.46 284.5 98.3 0.51 0.6886 0.9988 1975524 ChemDiv1_011228 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccc(c3)[N+](=O)[O-])N)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O09 compound treatment 275.5 90.1 0.47 284.4 98.2 0.51 0.6933 0.9991 1298980 ChemDiv1_011229 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(C)c4ccc(OC)c(c14)S(=O)(=O)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O10 compound treatment 277.1 91.7 0.48 280.9 94.7 0.49 0.6864 0.9999 1975525 ChemDiv1_011230 Cc1cc(ccc1[N+](=O)[O-])c2ccc(o2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O11 compound treatment 285.7 100.0 0.52 292.0 106.0 0.55 0.7589 0.9997 1975526 ChemDiv1_011231 Cc1cccc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4cccs4)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O12 compound treatment 386.8 201.0 1.05 383.4 197.0 1.03 1.4678 0.9999 1718948 ChemDiv1_011232 CC(=O)OCc1cc(C2C(=C(N)OC(=C2C#N)N)C#N)c(C)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O13 compound treatment 278.1 92.7 0.48 283.7 97.5 0.51 0.7004 0.9997 1268230 ChemDiv1_011233 CCOC(=O)C1=C(C)NC(=O)NC1c2c(OCC(=O)N3CCCCC3)ccc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O14 compound treatment 278.0 92.6 0.48 280.9 94.7 0.49 0.6897 1.0 1975527 ChemDiv1_011234 CC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O15 compound treatment 273.4 88.0 0.46 280.7 94.5 0.49 0.672 0.9994 1975528 ChemDiv1_011235 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O16 compound treatment 281.2 95.8 0.5 286.4 100.0 0.52 0.7217 0.9998 1975529 ChemDiv1_011236 CC1=C(C(C(=C(N)O1)C#N)c2cccc(Cl)c2)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O17 compound treatment 276.3 90.9 0.47 279.3 93.1 0.48 0.6776 0.9999 1125614 ChemDiv1_011237 CCOC(=O)C1=C(C)NC(=O)NC1c2c(OCC(=O)N3CCOCC3)ccc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O18 compound treatment 275.5 90.1 0.47 275.7 89.5 0.47 0.6614 1.0 1531706 ChemDiv1_011238 COCC1=C(C#N)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O19 compound treatment 281.2 95.8 0.5 280.3 94.1 0.49 0.6993 0.9999 1337800 ChemDiv1_011239 COc1ccc(cc1)c2cc(nc(SCC(=O)NC3CC3)c2C#N)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O20 compound treatment 280.0 94.6 0.49 276.2 90.0 0.47 0.6798 0.9996 1975530 ChemDiv1_011240 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3cccc(c3)C(F)(F)F)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O21 compound treatment 282.8 97.4 0.51 282.6 96.4 0.5 0.7137 1.0 1975531 ChemDiv1_011241 Clc1ccc(Nc2nc(Cl)nc(n2)N3CCOCC3)nc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O22 compound treatment 277.1 91.7 0.48 276.8 90.6 0.47 0.6713 1.0 1975532 ChemDiv1_011242 CCOC(=O)c1c(CSc2nc(C)c(C/C=C/C)c(C)c2C#N)n(C)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O23 mock treatment 277.2 91.8 0.48 277.2 91.0 0.47 0.6732 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 O24 mock treatment 101.5 -83.9 -0.44 93.4 -92.8 -0.48 -0.6505 -0.9988 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P01 compound treatment 288.4 103.0 0.54 293.0 107.0 0.56 0.7725 0.9999 1975533 ChemDiv1_011243 COCC1=C(C(C(=C(N)O1)C#N)c2ccc(F)c(Br)c2)C(=O)OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P02 compound treatment 280.7 95.3 0.5 281.0 94.8 0.49 0.7 1.0 1975534 ChemDiv1_011244 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(Br)cc3)C(=O)CCC2)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P03 compound treatment 284.1 98.7 0.51 285.7 99.5 0.52 0.7298 1.0 1975535 ChemDiv1_011245 CCOC(=O)C1=C(OC(=C(C#N)C1c2cccc(Br)c2)N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P04 compound treatment 285.6 100.0 0.52 287.6 101.0 0.53 0.7424 1.0 1975536 ChemDiv1_011246 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(Br)s4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P05 compound treatment 280.4 95.0 0.5 284.6 98.4 0.51 0.7122 0.9999 1285709 ChemDiv1_011247 CC(C)OC(=O)COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P06 compound treatment 278.6 93.2 0.49 283.0 96.8 0.5 0.6996 0.9999 1975537 ChemDiv1_011248 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3ccccn3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P07 compound treatment 313.9 129.0 0.67 314.7 129.0 0.67 0.9464 1.0 1975538 ChemDiv1_011249 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cn3)c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P08 compound treatment 281.6 96.2 0.5 286.5 100.0 0.52 0.7236 0.9998 1490369 ChemDiv1_011250 COc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P09 compound treatment 280.6 95.2 0.5 283.1 96.9 0.5 0.7074 1.0 1975539 ChemDiv1_011251 CCOC(=O)C1(O)CC(=NN1C(=O)c2cccc(Br)c2)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P10 compound treatment 279.4 94.0 0.49 283.5 97.3 0.51 0.7044 0.9999 1614784 ChemDiv1_011252 CSc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P11 compound treatment 276.3 90.9 0.47 283.9 97.7 0.51 0.6945 0.9994 1975540 ChemDiv1_011253 [O-][N+](=O)c1ccc(N/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccc(cc3)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P12 compound treatment 277.3 91.9 0.48 286.3 100.0 0.52 0.707 0.9992 1303258 ChemDiv1_011254 Cc1ccc(cc1Cl)c2ccc(o2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P13 compound treatment 278.1 92.7 0.48 281.4 95.2 0.49 0.6919 0.9999 1367677 ChemDiv1_011255 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P14 compound treatment 279.2 93.8 0.49 284.2 98.0 0.51 0.7063 0.9998 1975541 ChemDiv1_011256 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3ccc(cc3)C(C)(C)C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P15 compound treatment 277.6 92.2 0.48 283.7 97.5 0.51 0.6985 0.9997 1975542 ChemDiv1_011257 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P16 compound treatment 276.9 91.5 0.48 285.2 99.0 0.51 0.7015 0.9993 1975543 ChemDiv1_011258 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])C(F)(F)F)c3ccncc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P17 compound treatment 283.2 97.8 0.51 283.3 97.1 0.5 0.7177 1.0 1975544 ChemDiv1_011259 COc1ccc(cc1)C2=NN(C(C2)c3ccco3)c4nc(cs4)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P18 compound treatment 294.0 109.0 0.57 296.4 110.0 0.57 0.8057 1.0 1658665 ChemDiv1_011260 CCOC(=O)C1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P19 compound treatment 276.2 90.8 0.47 281.3 95.1 0.49 0.6845 0.9998 1210411 ChemDiv1_011261 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(F)cc4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P20 compound treatment 300.7 115.0 0.6 301.1 115.0 0.6 0.8477 1.0 1975545 ChemDiv1_011262 Cc1cccc(c1)C(=O)N2N=C(CC2(O)c3ccc(Br)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P21 compound treatment 291.8 106.0 0.56 291.5 105.0 0.55 0.7796 1.0 1975546 ChemDiv1_011263 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(F)cc3)c4ccc(Br)s4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P22 compound treatment 280.1 94.7 0.49 279.1 92.9 0.48 0.6908 0.9999 1975547 ChemDiv1_011264 Brc1ccccc1C(=O)OCCOCCNC2=NS(=O)(=O)c3ccccc23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P23 mock treatment 277.9 92.5 0.48 277.2 91.0 0.47 0.6757 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.618 P24 mock treatment 106.3 -79.1 -0.41 90.8 -95.4 -0.5 -0.6424 -0.9958 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A01 compound treatment 284.1 99.2 0.52 288.3 103.0 0.53 0.7438 0.9999 1220224 ChemDiv1_011265 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)c(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A02 compound treatment 283.3 98.4 0.51 283.5 98.0 0.51 0.7232 1.0 1975548 ChemDiv1_011266 CCN(CC)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A03 compound treatment 284.7 99.8 0.52 285.9 100.0 0.52 0.7372 1.0 1680030 ChemDiv1_011267 Fc1ccc2[nH]c3nc4ncc(Br)cc4nc3c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A04 compound treatment 278.9 94.0 0.49 280.4 94.9 0.49 0.6956 1.0 1975549 ChemDiv1_011268 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)N4CCN(C/C=C/c5ccccc5)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A05 compound treatment 278.8 93.9 0.49 282.8 97.3 0.51 0.7041 0.9999 1975550 ChemDiv1_011269 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCCOC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A06 compound treatment 279.0 94.1 0.49 279.2 93.7 0.49 0.6916 1.0 1693509 ChemDiv1_011270 COc1ccc(Nc2nc(NCc3ccco3)nc(OC)n2)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A07 compound treatment 283.2 98.3 0.51 283.1 97.6 0.51 0.7214 1.0 1975551 ChemDiv1_011271 CC(=O)c1sc(nc1C)N2N=C(CC2c3ccco3)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A08 compound treatment 282.3 97.4 0.51 288.8 103.0 0.54 0.739 0.9996 1194748 ChemDiv1_011272 O=C(CSc1nc2ccccc2[nH]1)OCC(=O)N3c4ccccc4Sc5ccccc35 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A09 compound treatment 278.9 94.0 0.49 285.1 99.6 0.52 0.7129 0.9996 1975552 ChemDiv1_011273 COC(=O)C1=C(N)N(C2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A10 compound treatment 284.2 99.3 0.52 282.4 96.9 0.5 0.7225 0.9999 1388274 ChemDiv1_011274 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A11 compound treatment 277.4 92.5 0.48 284.2 98.7 0.51 0.704 0.9995 1975553 ChemDiv1_011275 CCSc1nc2ccccc2n1CC(=O)Nc3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A12 compound treatment 278.8 93.9 0.49 282.6 97.1 0.5 0.7033 0.9999 1975554 ChemDiv1_011276 CCCCOc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(C)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A13 compound treatment 278.0 93.1 0.49 279.5 94.0 0.49 0.689 1.0 1715729 ChemDiv1_011277 CCN(CC)S(=O)(=O)c1cc(ccc1C)C(=O)N2CCN(CC2)C(=O)c3ccc(C)c(c3)S(=O)(=O)N(CC)CC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A14 compound treatment 311.2 126.0 0.66 315.6 130.0 0.68 0.9441 0.9999 1394110 ChemDiv1_011278 CCOC(=O)c1c(sc2CCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5cccnc5)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A15 compound treatment 277.0 92.1 0.48 277.5 92.0 0.48 0.6779 1.0 1975555 ChemDiv1_011279 Nc1cnn2C(SCC(=O)Nc3nnc(SCC(=O)Nc4ccccc4)s3)N=Nc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A16 compound treatment 306.7 122.0 0.64 309.0 124.0 0.64 0.9033 1.0 1975556 ChemDiv1_011280 COc1ccc2ccccc2c1/C=C/3\S/C(=N\c4ccccc4)/N(N(C)C)C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A17 compound treatment 318.2 133.0 0.7 315.2 130.0 0.67 0.9685 0.9999 1193154 ChemDiv1_011281 Nc1nc(SCC(=O)N2c3ccccc3Sc4ccccc24)c(C#N)cc1C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A18 compound treatment 280.6 95.7 0.5 274.1 88.6 0.46 0.6787 0.9992 1400320 ChemDiv1_011282 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccc6C(=O)OCc6c5)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A19 compound treatment 278.9 94.0 0.49 279.1 93.6 0.49 0.6908 1.0 1397443 ChemDiv1_011283 CCC(CC)C(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A20 compound treatment 282.9 98.0 0.51 283.7 98.2 0.51 0.7225 1.0 1975557 ChemDiv1_011284 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)cc(Br)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A21 compound treatment 277.2 92.3 0.48 278.5 93.0 0.48 0.6824 1.0 1355599 ChemDiv1_011285 CCOC(=O)c1c(c2ccccc2)n(Cc3ccccc3)c4ccc(OC(=O)C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A22 compound treatment 278.6 93.7 0.49 274.6 89.1 0.46 0.6732 0.9996 1975558 ChemDiv1_011286 Cc1cccc(/N=C\2/NC(=O)/C(=C/c3c(O)ccc4ccccc34)/S2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A23 mock treatment 278.0 93.1 0.49 276.4 90.9 0.47 0.6776 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 A24 mock treatment 79.9 -105.0 -0.55 77.0 -108.0 -0.56 -0.7861 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B01 compound treatment 283.1 98.2 0.51 282.9 97.4 0.51 0.7203 1.0 1975559 ChemDiv1_011287 NC1=C(C#N)C(C(=C(O1)c2ccccc2)Sc3ccc(cc3)[N+](=O)[O-])c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B02 compound treatment 281.9 97.0 0.51 283.7 98.2 0.51 0.7188 1.0 1172090 ChemDiv1_011288 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccccc5C(=O)O)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B03 compound treatment 276.7 91.8 0.48 279.4 93.9 0.49 0.6838 1.0 1536187 ChemDiv1_011289 CCOC(=O)c1c(CN2CCN(Cc3ccccc3)CC2)n(c4ccccc4)c5cc(Br)c(O)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B04 compound treatment 281.7 96.8 0.5 284.9 99.4 0.52 0.7225 0.9999 1975560 ChemDiv1_011290 Cc1ccc(/C=C/2\SC(=S)N(CN3CCCC3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B05 compound treatment 274.5 89.6 0.47 281.4 95.9 0.5 0.6831 0.9995 1975561 ChemDiv1_011291 COc1ccc(cc1OC)S(=O)(=O)NCCSc2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B06 compound treatment 279.5 94.6 0.49 285.4 99.9 0.52 0.7162 0.9997 1305593 ChemDiv1_011292 CCOc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B07 compound treatment 276.4 91.5 0.48 281.1 95.6 0.5 0.689 0.9998 1543160 ChemDiv1_011293 Clc1ccc(NC(=O)c2ccccc2NS(=O)(=O)c3cccc4nsnc34)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B08 compound treatment 279.8 94.9 0.5 286.5 101.0 0.53 0.7213 0.9996 1390051 ChemDiv1_011294 Nc1nnc(SCC(=O)Nc2nnc(SCC(=O)Nc3ccc(Br)cc3)s2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B09 compound treatment 276.4 91.5 0.48 280.0 94.5 0.49 0.6849 0.9999 1975562 ChemDiv1_011295 CC1=C(C(C(=C(N)O1)C#N)c2ccc(F)cc2)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B10 compound treatment 275.5 90.6 0.47 282.1 96.6 0.5 0.6893 0.9995 1975563 ChemDiv1_011296 CCN/1C(=O)/C(=C\2/C=Cc3ccccc3N2CC)/S\C1=N/c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B11 compound treatment 280.9 96.0 0.5 282.7 97.2 0.51 0.7114 1.0 1399348 ChemDiv1_011297 Clc1nc(NCCN2CCOCC2)nc(NCc3ccccc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B12 compound treatment 277.6 92.7 0.48 284.4 98.9 0.51 0.7055 0.9995 1975564 ChemDiv1_011298 O=C/1N(C2CCCCC2)/C(=N\c3ccccc3)/S\C1=C/c4cccnc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B13 compound treatment 293.3 108.0 0.57 294.6 109.0 0.57 0.8009 1.0 1975565 ChemDiv1_011299 O=C(NN1C(=O)C2C(C3C=CC2C4CC43)C1=O)C5CC5(c6ccccc6)c7ccccc7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B14 compound treatment 357.5 173.0 0.9 357.9 172.0 0.9 1.2704 1.0 1282326 ChemDiv1_011300 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)cc3)c(=O)n2C1c4cc(OC)c(OC)cc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B15 compound treatment 295.2 110.0 0.58 296.0 111.0 0.57 0.8131 1.0 1327714 ChemDiv1_011301 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4cccc(c4)C(=O)O)c(=O)n2C1c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B16 compound treatment 278.1 93.2 0.49 278.8 93.3 0.49 0.6868 1.0 1562546 ChemDiv1_011302 CCOC(=O)c1c(CSc2ccccc2)n(C)c3cc(Br)c(O)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B17 compound treatment 289.2 104.0 0.54 285.6 100.0 0.52 0.7527 0.9998 1368198 ChemDiv1_011303 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Cl)ccc3O)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B18 compound treatment 275.8 90.9 0.47 284.3 98.8 0.51 0.6985 0.9992 1975566 ChemDiv1_011304 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4ccc(o4)c5ccc(cc5)[N+](=O)[O-])c(=O)n23)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B19 compound treatment 278.3 93.4 0.49 277.8 92.3 0.48 0.6838 1.0 1445361 ChemDiv1_011305 CCOC(=O)c1c(CSc2nc3ccccc3s2)[nH]c4cc(Br)c(OC(=O)C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B20 compound treatment 276.4 91.5 0.48 276.0 90.5 0.47 0.6702 1.0 1975567 ChemDiv1_011306 COCC(CN1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B21 compound treatment 276.9 92.0 0.48 277.3 91.8 0.48 0.6768 1.0 1664761 ChemDiv1_011307 Fc1ccc(cc1Cl)N2C(Nc3ccccc3C2=O)c4ccc(Cl)cc4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B22 compound treatment 275.1 90.2 0.47 279.6 94.1 0.49 0.6786 0.9998 1485979 ChemDiv1_011308 CCCC(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B23 mock treatment 279.6 94.7 0.49 279.4 93.9 0.49 0.6945 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 B24 mock treatment 65.4 -120.0 -0.62 74.9 -111.0 -0.57 -0.8473 -0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C01 compound treatment 286.7 102.0 0.53 283.9 98.4 0.51 0.7372 0.9998 1263377 ChemDiv1_011309 CSc1nc2ccc(NC(=O)CSCC(=O)Nc3ccc4ccccc4c3)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C02 compound treatment 347.1 162.0 0.85 348.3 163.0 0.85 1.1967 1.0 1322568 ChemDiv1_011310 COC(=O)c1c(sc2CCCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5cccnc5)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C03 compound treatment 281.6 96.7 0.5 283.4 97.9 0.51 0.7166 1.0 1253038 ChemDiv1_011311 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C04 compound treatment 339.7 155.0 0.81 335.1 150.0 0.78 1.1209 0.9998 1451992 ChemDiv1_011312 COC(=O)c1c(sc2CCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5cccnc5)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C05 compound treatment 274.7 89.8 0.47 282.6 97.1 0.5 0.6882 0.9993 1975568 ChemDiv1_011313 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C06 compound treatment 281.8 96.9 0.51 287.2 102.0 0.53 0.7313 0.9997 1499493 ChemDiv1_011314 COc1nc(NCc2cccnc2)nc(n1)N3CCC(C)CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C07 compound treatment 275.5 90.6 0.47 283.9 98.4 0.51 0.6959 0.9992 1975569 ChemDiv1_011315 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)Nc4nc(cs4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C08 compound treatment 277.8 92.9 0.48 284.4 98.9 0.51 0.7062 0.9996 1975570 ChemDiv1_011316 [O-][N+](=O)c1ccc(Nc2nc(NCc3ccco3)nc(NCc4ccco4)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C09 compound treatment 306.4 122.0 0.63 307.7 122.0 0.64 0.8974 1.0 1633386 ChemDiv1_011317 CCOC(=O)COc1ccc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C10 compound treatment 269.7 84.8 0.44 284.9 99.4 0.52 0.6782 0.997 1491955 ChemDiv1_011318 Clc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C11 compound treatment 278.6 93.7 0.49 281.0 95.5 0.5 0.6967 1.0 1280895 ChemDiv1_011319 CCOc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C12 compound treatment 279.2 94.3 0.49 280.1 94.6 0.49 0.6956 1.0 1466729 ChemDiv1_011320 CC(C)COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C13 compound treatment 303.6 119.0 0.62 305.2 120.0 0.62 0.8779 1.0 1975571 ChemDiv1_011321 CN(C)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C14 compound treatment 299.5 115.0 0.6 300.6 115.0 0.6 0.8458 1.0 1299416 ChemDiv1_011322 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C15 compound treatment 292.3 107.0 0.56 295.2 110.0 0.57 0.7994 1.0 1975572 ChemDiv1_011323 CCOC(=O)C1=C(N)OC2=C(C1c3cc(Br)c(C)s3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C16 compound treatment 275.8 90.9 0.47 284.4 98.9 0.51 0.6989 0.9992 1975573 ChemDiv1_011324 COc1cccc(/C=C/2\SC(=N)NC2=O)c1OCc3ccc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C17 compound treatment 279.3 94.4 0.49 282.2 96.7 0.5 0.7037 0.9999 1975574 ChemDiv1_011325 CC(C)(C)C1(O)CC(=NN1C(=O)c2cccc(Cl)c2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C18 compound treatment 276.3 91.4 0.48 280.4 94.9 0.49 0.686 0.9999 1975575 ChemDiv1_011326 CC/1=NN(C(=O)\C1=C\c2cn(Cc3ccccc3)c4ccccc24)c5ccc(Cl)c(c5)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C19 compound treatment 274.7 89.8 0.47 280.0 94.5 0.49 0.6786 0.9997 1206196 ChemDiv1_011327 COc1nc(NCCN2CCOCC2)nc(Nc3ccccc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C20 compound treatment 275.1 90.2 0.47 274.7 89.2 0.46 0.6606 1.0 1333946 ChemDiv1_011328 Cc1cc(C)c(C#N)c(SCC(O)COc2ccc(cc2)C(C)(C)C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C21 compound treatment 274.3 89.4 0.47 281.0 95.5 0.5 0.6808 0.9995 1632518 ChemDiv1_011329 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCN(CC4)c5ccccc5)c6ccccc63 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C22 compound treatment 286.4 102.0 0.53 286.2 101.0 0.52 0.7446 1.0 1975576 ChemDiv1_011330 CN(C)c1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cc5OCOc5cc4Br)c(=O)n23)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C23 mock treatment 278.9 94.0 0.49 275.5 90.0 0.47 0.6776 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 C24 mock treatment 76.5 -108.0 -0.57 75.5 -110.0 -0.57 -0.8041 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D01 compound treatment 283.9 99.0 0.52 282.3 96.8 0.5 0.721 0.9999 1736956 ChemDiv1_011331 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C#N)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D02 compound treatment 265.3 80.4 0.42 266.0 80.5 0.42 0.5925 1.0 1975577 ChemDiv1_011332 CN(C)CCCNc1cc2oc3cccc(C)c3[nH]c2c4c(=O)c5ccccc5c(=O)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D03 compound treatment 281.5 96.6 0.5 284.7 99.2 0.52 0.721 0.9999 1945518 ChemDiv1_011333 Brc1cccc(c1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D04 compound treatment 279.0 94.1 0.49 281.8 96.3 0.5 0.7011 1.0 1975578 ChemDiv1_011334 Cn1c(SCC(=O)Nc2ccc3nc(SCC(=O)NC4CC4)sc3c2)nnc1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D05 compound treatment 281.8 96.9 0.51 288.7 103.0 0.54 0.7368 0.9996 1975579 ChemDiv1_011335 CCOc1cc(Br)c(C=C2C(=O)N(C)C(=S)N(C)C2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D06 compound treatment 280.8 95.9 0.5 289.6 104.0 0.54 0.7364 0.9992 1975580 ChemDiv1_011336 COc1ccc(OC)c(/C=C\2/S\C(=N\c3ccccc3)\N(CC=C)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D07 compound treatment 296.2 111.0 0.58 298.0 113.0 0.58 0.8241 1.0 1975581 ChemDiv1_011337 CCOc1ccc2nc(Sc3ccc(C=C4C(=O)NC(=S)NC4=O)o3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D08 compound treatment 283.1 98.2 0.51 286.6 101.0 0.53 0.7339 0.9999 1975582 ChemDiv1_011338 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCCCCC3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D09 compound treatment 276.7 91.8 0.48 280.3 94.8 0.49 0.6871 0.9999 1975583 ChemDiv1_011339 CCCC1=C(C(C(=C(N)O1)C#N)c2ccc(F)cc2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D10 compound treatment 282.5 97.6 0.51 284.4 98.9 0.51 0.7236 1.0 1315404 ChemDiv1_011340 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2Cl)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D11 compound treatment 279.8 94.9 0.5 280.3 94.8 0.49 0.6986 1.0 1975584 ChemDiv1_011341 COc1ccc(Nc2nc(Cl)nc(NCC=C)n2)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D12 compound treatment 283.9 99.0 0.52 291.4 106.0 0.55 0.7545 0.9995 1924594 ChemDiv1_011342 OC(=O)c1cccc(c1)N2C(=O)C3C4C=CC(C3C2=O)C4=C(c5ccccc5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D13 compound treatment 302.2 117.0 0.61 302.9 117.0 0.61 0.8643 1.0 1371037 ChemDiv1_011343 CCOC(=O)CC1=C(C(C(=C(N)O1)C#N)c2ccc(C)cc2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D14 compound treatment 328.6 144.0 0.75 320.7 135.0 0.7 1.0271 0.9995 1199808 ChemDiv1_011344 CCOC(=O)c1c(CN2CCCCC2)n(C3CCCCC3)c4cc(Br)c(O)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D15 compound treatment 288.0 103.0 0.54 288.2 103.0 0.53 0.7578 1.0 1850655 ChemDiv1_011345 CCOc1ccc(/C=C/2\CN(C)CC3=C2OC(=C(C#N)C3c4ccc(OCC)cc4)N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D16 compound treatment 282.8 97.9 0.51 286.3 101.0 0.52 0.7317 0.9999 1133667 ChemDiv1_011346 CCOC(=O)c1c(CS(=O)(=O)c2ccccc2)n(C)c3cc(Br)c(O)c(CN(C)C)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D17 compound treatment 382.8 198.0 1.03 374.8 189.0 0.98 1.4258 0.9997 1339490 ChemDiv1_011347 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(O)cc3Br)c(=O)n2C1c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D18 compound treatment 277.0 92.1 0.48 276.4 90.9 0.47 0.6739 1.0 1975585 ChemDiv1_011348 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cc5OCOc5cc4Br)c(=O)n23)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D19 compound treatment 274.7 89.8 0.47 274.7 89.2 0.46 0.6592 1.0 1975586 ChemDiv1_011349 FC(F)(F)c1cccc(c1)n2c(CSCC(=O)Nc3ccccc3)nc4ccccc4c2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D20 compound treatment 275.6 90.7 0.47 277.4 91.9 0.48 0.6724 1.0 1975587 ChemDiv1_011350 Cn1c(SCc2c[nH]c3cc(ccc23)[N+](=O)[O-])nc4sc5CCCCc5c4c1=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D21 compound treatment 275.1 90.2 0.47 277.4 91.9 0.48 0.6706 1.0 1975588 ChemDiv1_011351 [O-][N+](=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4F)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D22 compound treatment 273.5 88.6 0.46 274.7 89.2 0.46 0.6547 1.0 1298641 ChemDiv1_011352 CC1CCN(CC1)c2nc(Cl)nc(Nc3ccc4OCOc4c3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D23 mock treatment 275.5 90.6 0.47 275.8 90.3 0.47 0.6662 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 D24 mock treatment 76.4 -109.0 -0.57 77.8 -108.0 -0.56 -0.796 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E01 compound treatment 289.1 104.0 0.54 286.4 101.0 0.52 0.7553 0.9998 1780809 ChemDiv1_011353 [O-][N+](=O)c1ccc(Oc2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E02 compound treatment 283.2 98.3 0.51 284.2 98.7 0.51 0.7254 1.0 1449430 ChemDiv1_011354 CC1=C(C(NC(=O)N1)c2cccc(Br)c2)C(=O)OC3CCCCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E03 compound treatment 279.6 94.7 0.49 286.9 101.0 0.53 0.7221 0.9995 1564780 ChemDiv1_011355 C1CCC(CC1)Nc2nc3nonc3nc2NC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E04 compound treatment 278.6 93.7 0.49 279.7 94.2 0.49 0.6919 1.0 1975589 ChemDiv1_011356 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E05 compound treatment 279.2 94.3 0.49 284.0 98.5 0.51 0.7099 0.9998 1393454 ChemDiv1_011357 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E06 compound treatment 281.0 96.1 0.5 282.7 97.2 0.51 0.7118 1.0 1975590 ChemDiv1_011358 Clc1nc(NCc2cccnc2)nc(Nc3ccccc3)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E07 compound treatment 280.6 95.7 0.5 276.6 91.1 0.47 0.6879 0.9997 1393662 ChemDiv1_011359 Clc1cccc(Nc2nc3nonc3nc2N4CCCCC4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E08 compound treatment 278.0 93.1 0.49 283.1 97.6 0.51 0.7022 0.9998 1938298 ChemDiv1_011360 CCSCCOC(=O)C1=C(C)NC(=O)NC1c2cc(OC)c(OC)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E09 compound treatment 282.4 97.5 0.51 282.8 97.3 0.51 0.7173 1.0 1276030 ChemDiv1_011361 CC1CCN(CC1)c2nc3nonc3nc2Nc4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E10 compound treatment 280.4 95.5 0.5 285.3 99.8 0.52 0.7191 0.9998 1434598 ChemDiv1_011362 Oc1ccc(Nc2nc(Nc3ccc(O)cc3)nc(n2)N4CCOCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E11 compound treatment 294.2 109.0 0.57 295.1 110.0 0.57 0.8061 1.0 1197853 ChemDiv1_011363 CC(C)(C)c1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E12 compound treatment 273.3 88.4 0.46 278.2 92.7 0.48 0.6669 0.9998 1975591 ChemDiv1_011364 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(O)c(c3)[N+](=O)[O-])c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E13 compound treatment 304.6 120.0 0.62 308.7 123.0 0.64 0.8944 0.9999 1975592 ChemDiv1_011365 CN(C)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E14 compound treatment 307.1 122.0 0.64 309.6 124.0 0.65 0.907 1.0 1975593 ChemDiv1_011366 COc1ccc(OC)c(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E15 compound treatment 284.5 99.6 0.52 289.5 104.0 0.54 0.7497 0.9998 1209581 ChemDiv1_011367 CCC1=NN(C(=O)c2ccccc2C)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E16 compound treatment 295.1 110.0 0.57 299.0 114.0 0.59 0.8237 0.9999 1975594 ChemDiv1_011368 COc1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)cc1Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E17 compound treatment 278.8 93.9 0.49 280.6 95.1 0.49 0.696 1.0 1625882 ChemDiv1_011369 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E18 compound treatment 277.7 92.8 0.48 282.5 97.0 0.5 0.6989 0.9998 1975595 ChemDiv1_011370 CC/1=NN(C(=O)\C1=C/c2cc([N+](=O)[O-])c(cc2N3CCOCC3)N4CCOCC4)c5ccc(Cl)c(c5)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E19 compound treatment 277.3 92.4 0.48 279.4 93.9 0.49 0.686 1.0 1975596 ChemDiv1_011371 COC(=O)c1nnn(c1CSc2nc3ccccc3s2)c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E20 compound treatment 277.3 92.4 0.48 276.9 91.4 0.48 0.6768 1.0 1975597 ChemDiv1_011372 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccccc2/C=C/3\N=C(OC3=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E21 compound treatment 275.3 90.4 0.47 276.2 90.7 0.47 0.6669 1.0 1388051 ChemDiv1_011373 Cc1ccc(Nc2nc(Cl)nc(n2)N3CCOCC3)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E22 compound treatment 281.4 96.5 0.5 283.7 98.2 0.51 0.717 1.0 1975598 ChemDiv1_011374 Cc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(o3)c4ccc(cc4)C(=O)O)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E23 mock treatment 276.2 91.3 0.48 279.0 93.5 0.49 0.6805 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 E24 mock treatment 77.0 -108.0 -0.56 76.8 -109.0 -0.56 -0.7975 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F01 compound treatment 285.3 100.0 0.52 287.5 102.0 0.53 0.7453 1.0 1975599 ChemDiv1_011375 Nc1nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])c(C#N)c(c1C#N)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F02 compound treatment 276.1 91.2 0.48 273.9 88.4 0.46 0.6614 0.9999 1975600 ChemDiv1_011376 CC(C)(C)c1ccc2[nH]c3c(cc(NCCO)c4c(=O)c5ccccc5c(=O)c34)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F03 compound treatment 278.4 93.5 0.49 285.6 100.0 0.52 0.7129 0.9995 1632129 ChemDiv1_011377 CCCOc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F04 compound treatment 279.6 94.7 0.49 278.6 93.1 0.48 0.6916 0.9999 1975601 ChemDiv1_011378 CCOC(=O)C1=C(N(C)C(=O)NC1c2ccc(OC(F)F)c(OC)c2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F05 compound treatment 277.6 92.7 0.48 284.8 99.3 0.52 0.707 0.9995 1649620 ChemDiv1_011379 Brc1ccc2n(CCc3ccccc3)c4nc5ccccc5nc4c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F06 compound treatment 280.0 95.1 0.5 281.3 95.8 0.5 0.703 1.0 1975602 ChemDiv1_011380 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc3cccnc3)OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F07 compound treatment 283.7 98.8 0.52 286.5 101.0 0.53 0.7357 1.0 1975603 ChemDiv1_011381 CCSCCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(O)c(OC)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F08 compound treatment 279.9 95.0 0.5 288.8 103.0 0.54 0.7302 0.9992 1975604 ChemDiv1_011382 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F09 compound treatment 281.3 96.4 0.5 285.5 100.0 0.52 0.7232 0.9999 1258308 ChemDiv1_011383 CCCC1=C(C(C(=C(N)O1)C#N)c2cccc(F)c2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F10 compound treatment 269.1 84.2 0.44 276.3 90.8 0.47 0.6444 0.9994 1975605 ChemDiv1_011384 CC1=C(C(C(=C(N)O1)C#N)c2cccs2)C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F11 compound treatment 281.5 96.6 0.5 282.9 97.4 0.51 0.7144 1.0 1564790 ChemDiv1_011385 Cc1ccc(NC(=O)CSc2nnc(NC(=O)CSc3nnc4n(N)cnn34)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F12 compound treatment 290.3 105.0 0.55 295.4 110.0 0.57 0.7928 0.9998 1174585 ChemDiv1_011386 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5ccc(OC)cc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F13 compound treatment 336.6 152.0 0.79 330.2 145.0 0.75 1.0915 0.9997 1975606 ChemDiv1_011387 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3ccccc3C(=O)O)\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F14 compound treatment 287.1 102.0 0.53 296.6 111.0 0.58 0.7854 0.9992 1709162 ChemDiv1_011388 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(C#Cc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F15 compound treatment 288.0 103.0 0.54 293.6 108.0 0.56 0.7777 0.9998 1975607 ChemDiv1_011389 Cc1ccc(C#N)c(SCC(=O)c2ccc(cc2)C(=O)CSc3nc(C)ccc3C#N)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F16 compound treatment 279.9 95.0 0.5 282.8 97.3 0.51 0.7081 0.9999 1975608 ChemDiv1_011390 CCOC(=O)c1c(CNC(=O)C)n(CCBr)c2cc(Br)c(OC)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F17 compound treatment 353.3 168.0 0.88 355.4 170.0 0.88 1.2457 1.0 1975609 ChemDiv1_011391 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(OC)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F18 compound treatment 292.4 108.0 0.56 296.1 111.0 0.57 0.8031 0.9999 1975610 ChemDiv1_011392 CCOc1ccccc1NC(=O)CSc2nc(N)c(C#N)cc2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F19 compound treatment 277.4 92.5 0.48 282.1 96.6 0.5 0.6963 0.9998 1149538 ChemDiv1_011393 COc1ccc(OC)c(Nc2nc3nonc3nc2Nc4cccc(C)c4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F20 compound treatment 277.7 92.8 0.48 280.2 94.7 0.49 0.6904 1.0 1358934 ChemDiv1_011394 Clc1ccc(C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F21 compound treatment 276.3 91.4 0.48 279.3 93.8 0.49 0.682 0.9999 1975611 ChemDiv1_011395 CCCCOc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(F)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F22 compound treatment 280.4 95.5 0.5 279.8 94.3 0.49 0.6989 1.0 1372308 ChemDiv1_011396 COc1ccc2C3CC(=NN3C(=O)c2c1OC)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F23 mock treatment 275.8 90.9 0.47 274.0 88.5 0.46 0.6606 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 F24 mock treatment 81.6 -103.0 -0.54 77.7 -108.0 -0.56 -0.7772 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G01 compound treatment 282.7 97.8 0.51 286.5 101.0 0.53 0.732 0.9999 1780808 ChemDiv1_011397 [O-][N+](=O)c1cc(Cl)ccc1c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G02 compound treatment 279.8 94.9 0.5 282.1 96.6 0.5 0.7052 1.0 1323386 ChemDiv1_011398 CCC1=NN(C(=O)c2ccccc2OC)C(O)(C1)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G03 compound treatment 280.1 95.2 0.5 284.0 98.5 0.51 0.7133 0.9999 1442382 ChemDiv1_011399 Cc1ccc2NC(=O)C3(C(=C(N)OC4=C3C(=O)CCC4)C#N)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G04 compound treatment 279.1 94.2 0.49 282.6 97.1 0.5 0.7044 0.9999 1637247 ChemDiv1_011400 CCOC(=O)C1(O)CC(=NN1C(=O)c2ccc(cc2)c3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G05 compound treatment 277.8 92.9 0.48 283.6 98.1 0.51 0.7033 0.9997 1646662 ChemDiv1_011401 COc1ccc(OC)c(c1)N(CC(=O)Nc2cccc(Cl)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G06 compound treatment 280.3 95.4 0.5 283.3 97.8 0.51 0.7114 0.9999 1975612 ChemDiv1_011402 COC(=O)c1ccc(/C=C/2\C(=O)N(N=C2c3ccccc3)c4ccc(cc4)[N+](=O)[O-])cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G07 compound treatment 277.1 92.2 0.48 284.5 99.0 0.51 0.704 0.9994 1975613 ChemDiv1_011403 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(C)s3)C(=O)CCC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G08 compound treatment 279.7 94.8 0.49 288.9 103.0 0.54 0.7298 0.9991 1975614 ChemDiv1_011404 CC(=O)Oc1ccc(cc1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G09 compound treatment 282.2 97.3 0.51 284.1 98.6 0.51 0.7214 1.0 1975615 ChemDiv1_011405 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(Br)cs3)C(=O)CC(C)(C)C2)c4cccc(c4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G10 compound treatment 287.1 102.0 0.53 288.6 103.0 0.54 0.756 1.0 1645983 ChemDiv1_011406 CCOC(=O)c1c(CNC(=O)C)n(CC(=O)OC)c2cc(Br)c(OC)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G11 compound treatment 282.1 97.2 0.51 287.3 102.0 0.53 0.7328 0.9998 1975616 ChemDiv1_011407 [O-][N+](=O)c1ccccc1C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G12 compound treatment 284.7 99.8 0.52 289.2 104.0 0.54 0.7493 0.9998 1545587 ChemDiv1_011408 COc1ccccc1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Oc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G13 compound treatment 290.9 106.0 0.55 294.1 109.0 0.56 0.7902 0.9999 1975617 ChemDiv1_011409 O=C(CN1CCOCC1)Nc2nnc(SCC(=O)N(c3ccccc3)c4ccccc4)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G14 compound treatment 286.9 102.0 0.53 293.3 108.0 0.56 0.7725 0.9997 1975618 ChemDiv1_011410 COc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(OCC(C)C)cc3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G15 compound treatment 290.4 106.0 0.55 290.8 105.0 0.55 0.7763 1.0 1638738 ChemDiv1_011411 Nc1nnc(SCC(=O)Nc2ccc(NC(=O)CSc3nnc(N)s3)c(Cl)c2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G16 compound treatment 288.7 104.0 0.54 295.9 110.0 0.57 0.7887 0.9996 1975619 ChemDiv1_011412 COc1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G17 compound treatment 285.4 101.0 0.52 284.1 98.6 0.51 0.7332 0.9999 1182670 ChemDiv1_011413 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CCC2)c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G18 compound treatment 273.1 88.2 0.46 280.5 95.0 0.49 0.6746 0.9994 1938391 ChemDiv1_011414 COc1cc(cc(OC)c1OC)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G19 compound treatment 279.5 94.6 0.49 281.4 95.9 0.5 0.7015 1.0 1362381 ChemDiv1_011415 COc1nccnc1NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3cc4ccccc4oc3=O)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G20 compound treatment 285.8 101.0 0.53 286.1 101.0 0.52 0.742 1.0 1569847 ChemDiv1_011416 CCOC(=O)c1c(CSc2nc(CC(C)C)ccc2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G21 compound treatment 279.6 94.7 0.49 272.9 87.4 0.45 0.6706 0.9991 1975620 ChemDiv1_011417 COC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G22 compound treatment 275.5 90.6 0.47 277.0 91.5 0.48 0.6706 1.0 1938286 ChemDiv1_011418 Cc1cc2nc3sc(=Cc4ccc(o4)c5cc(ccc5Cl)[N+](=O)[O-])c(=O)n3c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G23 mock treatment 276.1 91.2 0.48 278.1 92.6 0.48 0.6768 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 G24 mock treatment 81.5 -103.0 -0.54 80.8 -105.0 -0.54 -0.7662 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H01 compound treatment 282.7 97.8 0.51 284.9 99.4 0.52 0.7262 1.0 1975621 ChemDiv1_011419 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc(SCC(=O)N)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H02 compound treatment 306.4 122.0 0.63 308.1 123.0 0.64 0.8989 1.0 1975622 ChemDiv1_011420 CCOc1cc(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)ccc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H03 compound treatment 281.5 96.6 0.5 279.8 94.3 0.49 0.703 0.9999 1470787 ChemDiv1_011421 CCOC(=O)c1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCC(C)C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H04 compound treatment 280.2 95.3 0.5 283.1 97.6 0.51 0.7103 0.9999 1683538 ChemDiv1_011422 CCSc1nc2ccc(NC(=O)CSc3nc4ccccc4[nH]3)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H05 compound treatment 278.4 93.5 0.49 282.5 97.0 0.5 0.7015 0.9999 1453219 ChemDiv1_011423 Fc1ccc(Cn2c3ccc(Br)cc3c4nc5ccccc5nc24)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H06 compound treatment 281.6 96.7 0.5 287.7 102.0 0.53 0.7324 0.9997 1975623 ChemDiv1_011424 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H07 compound treatment 279.5 94.6 0.49 282.8 97.3 0.51 0.7066 0.9999 1269081 ChemDiv1_011425 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCOCC4)c5ccccc53 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H08 compound treatment 276.1 91.2 0.48 277.4 91.9 0.48 0.6742 1.0 1137492 ChemDiv1_011426 COc1ccc(cc1)C(=O)c2sc3nc(C)c(C(=O)Nc4ccccc4)c(C)c3c2N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H09 compound treatment 273.0 88.1 0.46 279.7 94.2 0.49 0.6713 0.9995 1657857 ChemDiv1_011427 CCCC1=C(C(C(=C(N)O1)C#N)c2ccc(OC)c(OC)c2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H10 compound treatment 280.4 95.5 0.5 279.9 94.4 0.49 0.6993 1.0 1975624 ChemDiv1_011428 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2[N+](=O)[O-])C(=O)OCC=C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H11 compound treatment 280.1 95.2 0.5 283.6 98.1 0.51 0.7118 0.9999 1394913 ChemDiv1_011429 CCOC(=O)c1nnn(c1CSc2nc3ccc(OCC)cc3s2)c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H12 compound treatment 293.0 108.0 0.56 298.7 113.0 0.59 0.8149 0.9998 1944061 ChemDiv1_011430 CCOc1cc(/C=C\2/SC(=N)NC2=O)ccc1OCc3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H13 compound treatment 285.1 100.0 0.52 289.7 104.0 0.54 0.7527 0.9998 1975625 ChemDiv1_011431 CCOC(=O)CSc1nc2ccccc2n1C(=O)OCCCl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H14 compound treatment 285.7 101.0 0.53 292.1 107.0 0.55 0.7637 0.9997 1975626 ChemDiv1_011432 Nc1c(sc2nc(N)c(C#N)c(c3cccs3)c12)C(=O)Nc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H15 compound treatment 289.8 105.0 0.55 294.2 109.0 0.57 0.7865 0.9999 1310454 ChemDiv1_011433 CCOC(=O)c1c(CSc2nc(C)c(C)c(C)c2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H16 compound treatment 278.8 93.9 0.49 290.3 105.0 0.54 0.7316 0.9986 1975627 ChemDiv1_011434 CCOC(=O)CNCc1c(C(=O)OCC)c2cc(OC)c(Br)cc2n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H17 compound treatment 318.9 134.0 0.7 320.1 135.0 0.7 0.9891 1.0 1975628 ChemDiv1_011435 CC1CCN(CN2C(=O)/C(=C\c3ccc(cc3)C(C)(C)C)/SC2=S)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H18 compound treatment 289.6 105.0 0.55 296.5 111.0 0.58 0.7943 0.9996 1975629 ChemDiv1_011436 CCOc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H19 compound treatment 302.9 118.0 0.62 305.4 120.0 0.62 0.876 1.0 1975630 ChemDiv1_011437 FC(F)(F)c1cccc(Nc2nc3nonc3nc2Nc4cccc(c4)C(F)(F)F)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H20 compound treatment 281.0 96.1 0.5 288.5 103.0 0.54 0.7331 0.9995 1545650 ChemDiv1_011438 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc5ccccc5[nH]c4=O)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H21 compound treatment 277.3 92.4 0.48 277.2 91.7 0.48 0.6779 1.0 1975631 ChemDiv1_011439 CCCCCCCCCCn1c(CBr)c(C(=O)OCC)c2cc(OC(=O)C)ccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H22 compound treatment 274.6 89.7 0.47 277.6 92.1 0.48 0.6695 0.9999 1975632 ChemDiv1_011440 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc(Br)ccc4O)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H23 mock treatment 277.7 92.8 0.48 283.2 97.7 0.51 0.7015 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 H24 mock treatment 77.8 -107.0 -0.56 74.9 -111.0 -0.57 -0.8015 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I01 compound treatment 286.4 102.0 0.53 288.4 103.0 0.53 0.7527 1.0 1975633 ChemDiv1_011441 CCOC(=O)CSc1nc2ccc(cc2s1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I02 compound treatment 281.1 96.2 0.5 282.0 96.5 0.5 0.7096 1.0 1975634 ChemDiv1_011442 CCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I03 compound treatment 282.9 98.0 0.51 282.0 96.5 0.5 0.7162 1.0 1726267 ChemDiv1_011443 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccc(C)cc32)C(=C(N)O1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I04 compound treatment 278.4 93.5 0.49 283.6 98.1 0.51 0.7055 0.9998 1975635 ChemDiv1_011444 [O-][N+](=O)c1cccc(c1)C2SCCN2C(=O)c3cc4ccc(Br)cc4oc3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I05 compound treatment 290.6 106.0 0.55 288.4 103.0 0.53 0.7682 0.9999 1502137 ChemDiv1_011445 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)N(c3ccccc3)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I06 compound treatment 280.3 95.4 0.5 284.2 98.7 0.51 0.7147 0.9999 1155132 ChemDiv1_011446 CC(=O)Nc1ccc2nc(SCC(=O)c3ccc(Br)cc3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I07 compound treatment 282.4 97.5 0.51 282.7 97.2 0.51 0.717 1.0 1286476 ChemDiv1_011447 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(c4ccccc4)c5ccc(O)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I08 compound treatment 278.0 93.1 0.49 284.6 99.1 0.52 0.7077 0.9996 1391952 ChemDiv1_011448 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc(Br)cc3)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I09 compound treatment 276.5 91.6 0.48 286.6 101.0 0.53 0.7095 0.9989 1975636 ChemDiv1_011449 [O-][N+](=O)c1cc([N+](=O)[O-])c(Sc2nc3ccccc3s2)c(c1)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I10 compound treatment 280.8 95.9 0.5 287.9 102.0 0.53 0.7302 0.9995 1635599 ChemDiv1_011450 CC1=C(C(NC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OCc3ccc4OCOc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I11 compound treatment 280.0 95.1 0.5 276.9 91.4 0.48 0.6868 0.9998 1975637 ChemDiv1_011451 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)C4CC4(c5ccccc5)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I12 compound treatment 282.3 97.4 0.51 282.5 97.0 0.5 0.7159 1.0 1266105 ChemDiv1_011452 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CCC2)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I13 compound treatment 280.5 95.6 0.5 287.0 102.0 0.53 0.7258 0.9996 1975638 ChemDiv1_011453 Brc1ccc(cc1)C(=O)Oc2cccc(NC3=NS(=O)(=O)c4ccccc34)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I14 compound treatment 283.4 98.5 0.51 286.4 101.0 0.52 0.7343 0.9999 1975639 ChemDiv1_011454 COc1ccc(/C=C\2/S/C(=N\c3ccc(C)cc3)/NC2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I15 compound treatment 283.2 98.3 0.51 286.9 101.0 0.53 0.7354 0.9999 1927054 ChemDiv1_011455 COc1ccc(cc1)N(CC(=O)Nc2ccc(Cl)cc2C)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I16 compound treatment 280.6 95.7 0.5 286.3 101.0 0.52 0.7236 0.9997 1975640 ChemDiv1_011456 COc1ccc2nc(NC(=O)COC(=O)CC(NC(=O)c3ccccc3)c4ccccc4)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I17 compound treatment 282.4 97.5 0.51 286.8 101.0 0.53 0.732 0.9998 1286358 ChemDiv1_011457 COC(=O)C1=C(N)N(C2=C(C1c3ccc(Cl)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I18 compound treatment 277.8 92.9 0.48 281.4 95.9 0.5 0.6952 0.9999 1293122 ChemDiv1_011458 Clc1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I19 compound treatment 282.6 97.7 0.51 283.9 98.4 0.51 0.7221 1.0 1395650 ChemDiv1_011459 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccccc4F)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I20 compound treatment 277.7 92.8 0.48 283.7 98.2 0.51 0.7033 0.9996 1975641 ChemDiv1_011460 Cc1cc(c2c(N)c(sc2n1)C(=O)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I21 compound treatment 282.8 97.9 0.51 281.5 96.0 0.5 0.714 0.9999 1975642 ChemDiv1_011461 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2ccc3OCOc3c2)c4cc(Cl)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I22 compound treatment 282.6 97.7 0.51 279.0 93.5 0.49 0.7041 0.9997 1951531 ChemDiv1_011462 CN1CCN(CC1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I23 mock treatment 278.1 93.2 0.49 282.0 96.5 0.5 0.6985 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 I24 mock treatment 83.0 -102.0 -0.53 80.7 -105.0 -0.54 -0.761 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J01 compound treatment 295.5 111.0 0.58 295.5 110.0 0.57 0.8123 1.0 1975643 ChemDiv1_011463 CC(C)c1c(C#N)c(N)nc2sc(C(=O)c3ccc(cc3)[N+](=O)[O-])c(N)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J02 compound treatment 282.1 97.2 0.51 284.4 98.9 0.51 0.7221 1.0 1781824 ChemDiv1_011464 COc1cc([N+](=O)[O-])c(Cl)cc1c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J03 compound treatment 277.9 93.0 0.49 282.9 97.4 0.51 0.7011 0.9998 1975644 ChemDiv1_011465 Cc1cccc(C)c1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J04 compound treatment 279.8 94.9 0.5 283.1 97.6 0.51 0.7088 0.9999 1567238 ChemDiv1_011466 Nc1ccc2nc(SCC(=O)Nc3ccc4nc(SCC(=O)NC5CC5)sc4c3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J05 compound treatment 293.4 109.0 0.57 295.0 110.0 0.57 0.8028 1.0 1975645 ChemDiv1_011467 COc1cc(/C=C\2/SC(=N)NC2=O)ccc1OCc3ccccc3F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J06 compound treatment 281.8 96.9 0.51 280.6 95.1 0.49 0.707 0.9999 1728083 ChemDiv1_011468 O=C(CCc1ccccc1)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J07 compound treatment 278.1 93.2 0.49 286.3 101.0 0.52 0.7143 0.9993 1975646 ChemDiv1_011469 Cc1nn2c(c1[N+](=O)[O-])n3nc(C)c([N+](=O)[O-])c3n4nc(C)c([N+](=O)[O-])c24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J08 compound treatment 297.0 112.0 0.58 302.5 117.0 0.61 0.8436 0.9998 1975647 ChemDiv1_011470 CCCCOc1ccc(NC(=O)c2sc3nc(N)c(C#N)cc3c2N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J09 compound treatment 275.4 90.5 0.47 278.7 93.2 0.48 0.6764 0.9999 1975648 ChemDiv1_011471 CCCC1=C(C(C(=C(N)O1)C#N)c2cccc(c2)[N+](=O)[O-])C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J10 compound treatment 284.0 99.1 0.52 287.8 102.0 0.53 0.7416 0.9999 1382897 ChemDiv1_011472 CCOC(=O)c1c2CN(CCn2c3cc(Br)c(OC)cc13)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J11 compound treatment 275.3 90.4 0.47 283.4 97.9 0.51 0.6934 0.9993 1975649 ChemDiv1_011473 CCN/1C(=O)/C(=C\2/C=Cc3ccccc3N2CC)/S\C1=N/c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J12 compound treatment 278.8 93.9 0.49 281.0 95.5 0.5 0.6974 1.0 1165690 ChemDiv1_011474 Cc1cccc(c1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J13 compound treatment 281.6 96.7 0.5 284.3 98.8 0.51 0.7199 1.0 1139419 ChemDiv1_011475 CCOC(=O)CSc1nc2ccccc2n1C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J14 compound treatment 285.5 101.0 0.52 288.6 103.0 0.54 0.7501 0.9999 1975650 ChemDiv1_011476 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc3cc(OC)ccc3oc2=O)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J15 compound treatment 279.5 94.6 0.49 285.4 99.9 0.52 0.7162 0.9997 1533064 ChemDiv1_011477 CCOC(=O)c1c(CSc2nc(C)cc(C)c2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J16 compound treatment 284.7 99.8 0.52 288.2 103.0 0.53 0.7457 0.9999 1261676 ChemDiv1_011478 CCOC(=O)c1c(CSc2nc3ccccc3s2)n(c4ccccc4)c5cc(Br)c(OC(=O)C)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J17 compound treatment 280.2 95.3 0.5 278.0 92.5 0.48 0.6916 0.9999 1975651 ChemDiv1_011479 Fc1ccc(N/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccccc3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J18 compound treatment 285.7 101.0 0.53 287.1 102.0 0.53 0.7453 1.0 1618230 ChemDiv1_011480 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2)n3nnc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J19 compound treatment 285.6 101.0 0.53 287.3 102.0 0.53 0.7457 1.0 1975652 ChemDiv1_011481 Cc1ccc(Sc2c(F)c3C(=O)c4ccccc4C(=O)c3c(F)c2Sc5ccc(C)cc5)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J20 compound treatment 284.1 99.2 0.52 285.2 99.7 0.52 0.7324 1.0 1579664 ChemDiv1_011482 CCOc1cc(cc(Cl)c1O)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J21 compound treatment 283.5 98.6 0.51 284.7 99.2 0.52 0.7284 1.0 1631566 ChemDiv1_011483 CCOC(=O)c1c(CN2CCCCC2)n(C)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J22 compound treatment 280.8 95.9 0.5 275.6 90.1 0.47 0.685 0.9995 1975653 ChemDiv1_011484 COc1ccccc1C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J23 mock treatment 278.3 93.4 0.49 276.8 91.3 0.47 0.6802 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 J24 mock treatment 75.3 -110.0 -0.57 78.7 -107.0 -0.56 -0.7968 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K01 compound treatment 285.9 101.0 0.53 285.8 100.0 0.52 0.7413 1.0 1723745 ChemDiv1_011485 CSc1nc2ccc(NC(=O)CSc3nc4ccccc4[nH]3)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K02 compound treatment 280.1 95.2 0.5 277.2 91.7 0.48 0.6883 0.9998 1168551 ChemDiv1_011486 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(cc4)N(C)C)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K03 compound treatment 280.6 95.7 0.5 287.0 102.0 0.53 0.7261 0.9996 1975654 ChemDiv1_011487 Cc1cc(C)c(C#N)c(SCc2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4)N)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K04 compound treatment 277.8 92.9 0.48 276.4 90.9 0.47 0.6768 0.9999 1975655 ChemDiv1_011488 CCOC(=O)c1c(CNCCN(CC)CC)n(c2ccccc2)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K05 compound treatment 288.6 104.0 0.54 286.3 101.0 0.52 0.7531 0.9999 1728996 ChemDiv1_011489 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3sc4CCCCCc4c3C#N)c5cccnc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K06 compound treatment 287.0 102.0 0.53 290.6 105.0 0.55 0.763 0.9999 1502978 ChemDiv1_011490 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K07 compound treatment 286.7 102.0 0.53 290.5 105.0 0.55 0.7615 0.9999 1975656 ChemDiv1_011491 COc1ccc(Nc2nc(Cl)nc(NCc3cccnc3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K08 compound treatment 397.9 213.0 1.11 400.0 215.0 1.12 1.5742 1.0 1975657 ChemDiv1_011492 COc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(cc3)N(C)C)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K09 compound treatment 281.1 96.2 0.5 287.4 102.0 0.53 0.7294 0.9996 1181229 ChemDiv1_011493 COc1ccc(Cl)cc1NC(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K10 compound treatment 285.9 101.0 0.53 292.5 107.0 0.56 0.7659 0.9996 1585280 ChemDiv1_011494 Brc1ccc(cc1)C(=O)Nc2ccc3nc(SCC(=O)NC4CC4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K11 compound treatment 277.3 92.4 0.48 279.7 94.2 0.49 0.6871 1.0 1923662 ChemDiv1_011495 COc1ccc(OC)c(c1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K12 compound treatment 279.5 94.6 0.49 279.1 93.6 0.49 0.693 1.0 1273297 ChemDiv1_011496 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K13 compound treatment 284.0 99.1 0.52 282.4 96.9 0.5 0.7218 0.9999 1975658 ChemDiv1_011497 CCSc1nnc(NC(=O)COC(=O)CC(NC(=O)c2ccccc2)c3cccc(OC)c3)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K14 compound treatment 285.2 100.0 0.52 288.3 103.0 0.53 0.7479 0.9999 1975659 ChemDiv1_011498 COc1ccc(/N=C\2/NC(=O)/C(=C/c3c(OC)ccc4ccccc34)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K15 compound treatment 289.5 105.0 0.55 290.6 105.0 0.55 0.7722 1.0 1576345 ChemDiv1_011499 CCC1=NN(C(=O)c2ccccc2O)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K16 compound treatment 285.4 101.0 0.52 285.6 100.0 0.52 0.7387 1.0 1466228 ChemDiv1_011500 Nc1nnc(SCC(=O)Nc2nnc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)s2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K17 compound treatment 295.7 111.0 0.58 297.5 112.0 0.58 0.8204 1.0 1734890 ChemDiv1_011501 CCC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(OC)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K18 compound treatment 297.5 113.0 0.59 301.5 116.0 0.6 0.8418 0.9999 1154133 ChemDiv1_011502 COc1ccc(cc1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K19 compound treatment 279.0 94.1 0.49 280.0 94.5 0.49 0.6945 1.0 1975660 ChemDiv1_011503 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccccc5C4=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K20 compound treatment 306.8 122.0 0.64 310.0 125.0 0.65 0.9073 1.0 1930145 ChemDiv1_011504 COc1ccc(N(CC(=O)NCCSc2nc3ccccc3s2)S(=O)(=O)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K21 compound treatment 279.5 94.6 0.49 277.4 91.9 0.48 0.6868 0.9999 1975661 ChemDiv1_011505 Cc1ccc(cc1C)N2C(=O)/C(=C/c3cc(Br)ccc3O)/C(=O)NC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K22 compound treatment 280.2 95.3 0.5 279.4 93.9 0.49 0.6967 1.0 1975662 ChemDiv1_011506 CN(C)c1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4ccc(o4)c5ccc(cc5)[N+](=O)[O-])c(=O)n23)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K23 mock treatment 276.0 91.1 0.48 276.6 91.1 0.47 0.6709 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 K24 mock treatment 82.1 -103.0 -0.54 73.2 -112.0 -0.58 -0.7919 -0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L01 compound treatment 285.1 100.0 0.52 282.8 97.3 0.51 0.7273 0.9999 1785091 ChemDiv1_011507 Cc1ccc(cc1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Oc4ccccc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L02 compound treatment 287.1 102.0 0.53 285.5 100.0 0.52 0.7446 0.9999 1975663 ChemDiv1_011508 CCOC(=O)c1c(CSc2nc(C)cc(c2C#N)C(F)(F)F)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L03 compound treatment 281.4 96.5 0.5 281.5 96.0 0.5 0.7089 1.0 1975664 ChemDiv1_011509 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OS(=O)(=O)c3ccc(C)cc3)cc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L04 compound treatment 281.2 96.3 0.5 282.9 97.4 0.51 0.7133 1.0 1975665 ChemDiv1_011510 CCCCNC(=O)CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L05 compound treatment 277.3 92.4 0.48 284.1 98.6 0.51 0.7033 0.9995 1975666 ChemDiv1_011511 CCOc1cc(/C=C/2\C(=O)N(N=C2c3ccccc3)c4ccc(cc4)[N+](=O)[O-])ccc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L06 compound treatment 282.9 98.0 0.51 283.6 98.1 0.51 0.7221 1.0 1975667 ChemDiv1_011512 CCOC(=O)c1nnn(c1CSc2nc3cc(OC)ccc3[nH]2)c4nonc4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L07 compound treatment 286.0 101.0 0.53 284.8 99.3 0.52 0.738 0.9999 1853272 ChemDiv1_011513 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L08 compound treatment 286.0 101.0 0.53 288.6 103.0 0.54 0.7519 1.0 1781697 ChemDiv1_011514 COC(=O)C1C(C(=C(NC1=O)SCC(=O)OCc2ccccc2)C#N)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L09 compound treatment 277.4 92.5 0.48 279.6 94.1 0.49 0.6871 1.0 1138674 ChemDiv1_011515 CCCC1=C(C(C(=C(N)O1)C#N)c2cc(OC)c(OC)c(OC)c2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L10 compound treatment 281.2 96.3 0.5 285.1 99.6 0.52 0.7214 0.9999 1975668 ChemDiv1_011516 CSc1nnc(NC(=O)CSc2nn3c(SCC(=O)Nc4nnc(SC)s4)nnc3s2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L11 compound treatment 278.7 93.8 0.49 279.7 94.2 0.49 0.6923 1.0 1975669 ChemDiv1_011517 FC(F)(F)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)cc(c1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L12 compound treatment 275.6 90.7 0.47 280.6 95.1 0.49 0.6842 0.9998 1578453 ChemDiv1_011518 COc1ccc(cc1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L13 compound treatment 279.2 94.3 0.49 283.9 98.4 0.51 0.7096 0.9998 1975670 ChemDiv1_011519 CCCCOC(=O)n1c(SCC(=O)OCC)nc2ccccc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L14 compound treatment 287.5 103.0 0.54 288.8 103.0 0.54 0.7582 1.0 1925322 ChemDiv1_011520 FC(F)(F)COc1nc(nc(n1)N2CCN(Cc3ccccc3)CC2)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L15 compound treatment 286.3 101.0 0.53 290.1 105.0 0.54 0.7586 0.9999 1975671 ChemDiv1_011521 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCSc2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L16 compound treatment 290.6 106.0 0.55 291.3 106.0 0.55 0.7788 1.0 1975672 ChemDiv1_011522 Clc1cccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L17 compound treatment 283.0 98.1 0.51 281.9 96.4 0.5 0.7162 0.9999 1975673 ChemDiv1_011523 COc1ccc(OCC(CN(C)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(C)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L18 compound treatment 295.0 110.0 0.57 289.5 104.0 0.54 0.7884 0.9995 1975674 ChemDiv1_011524 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)Nc3cccnc3)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L19 compound treatment 357.9 173.0 0.9 356.0 171.0 0.89 1.2649 1.0 1360009 ChemDiv1_011525 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Br)c(=O)n2C1c5cc(OC)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L20 compound treatment 359.4 175.0 0.91 355.1 170.0 0.88 1.2671 0.9999 1250244 ChemDiv1_011526 CCOc1cc(ccc1OCc2ccccc2F)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L21 compound treatment 277.0 92.1 0.48 284.7 99.2 0.52 0.7044 0.9994 1591096 ChemDiv1_011527 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4ccc(OC(=O)C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L22 compound treatment 299.2 114.0 0.6 298.1 113.0 0.59 0.8355 1.0 1931161 ChemDiv1_011528 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4c(O)ccc5ccccc45)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L23 mock treatment 276.3 91.4 0.48 277.7 92.2 0.48 0.6761 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 L24 mock treatment 78.4 -107.0 -0.56 77.3 -108.0 -0.56 -0.7905 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M01 compound treatment 285.5 101.0 0.52 286.8 101.0 0.53 0.7435 1.0 1540637 ChemDiv1_011529 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3OC)c(=O)n2C1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M02 compound treatment 281.1 96.2 0.5 280.4 94.9 0.49 0.7037 1.0 1975675 ChemDiv1_011530 CC(C)Oc1ccccc1NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M03 compound treatment 297.4 113.0 0.59 299.0 114.0 0.59 0.8322 1.0 1975676 ChemDiv1_011531 Cc1cc(C)c(C#N)c(SCc2n[nH]c3OC(=C(C#N)[C@@H](c23)c4ccccc4[N+](=O)[O-])N)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M04 compound treatment 282.7 97.8 0.51 279.7 94.2 0.49 0.707 0.9998 1975677 ChemDiv1_011532 Cc1cccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M05 compound treatment 279.0 94.1 0.49 286.1 101.0 0.52 0.7169 0.9995 1210220 ChemDiv1_011533 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OCc5ccc(Cl)cc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M06 compound treatment 284.1 99.2 0.52 299.1 114.0 0.59 0.7835 0.9978 1509043 ChemDiv1_011534 CCOc1cc(ccc1OC)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M07 compound treatment 281.3 96.4 0.5 285.6 100.0 0.52 0.7236 0.9999 1975678 ChemDiv1_011535 Cc1ccc(cc1)C2=N/C(=C\c3ccccc3OS(=O)(=O)c4ccccc4)/C(=O)O2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M08 compound treatment 288.0 103.0 0.54 290.6 105.0 0.55 0.7667 1.0 1975679 ChemDiv1_011536 COc1ccc(OC)c(/C=C\2/S/C(=N\c3ccc(C)cc3)/NC2=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M09 compound treatment 282.2 97.3 0.51 280.2 94.7 0.49 0.707 0.9999 1616404 ChemDiv1_011537 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M10 compound treatment 279.5 94.6 0.49 283.2 97.7 0.51 0.7081 0.9999 1396344 ChemDiv1_011538 CC(C)COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc5ccccc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M11 compound treatment 287.0 102.0 0.53 286.4 101.0 0.52 0.7475 1.0 1975680 ChemDiv1_011539 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3cccc(C)c3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M12 compound treatment 271.0 86.1 0.45 280.4 94.9 0.49 0.6665 0.9989 1975681 ChemDiv1_011540 CCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M13 compound treatment 285.2 100.0 0.52 285.5 100.0 0.52 0.7376 1.0 1975682 ChemDiv1_011541 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccc(OC)c(Br)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M14 compound treatment 281.8 96.9 0.51 287.9 102.0 0.53 0.7339 0.9997 1975683 ChemDiv1_011542 COc1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M15 compound treatment 287.5 103.0 0.54 287.9 102.0 0.53 0.7549 1.0 1222027 ChemDiv1_011543 CCC1=NN(C(=O)c2ccc(C)cc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M16 compound treatment 280.7 95.8 0.5 281.5 96.0 0.5 0.7063 1.0 1975684 ChemDiv1_011544 CC(=O)c1ccc(NC(=O)CSc2nn3c(SCC(=O)Nc4ccc(cc4)C(=O)C)nnc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M17 compound treatment 297.4 113.0 0.59 297.5 112.0 0.58 0.8267 1.0 1975685 ChemDiv1_011545 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M18 compound treatment 286.2 101.0 0.53 292.8 107.0 0.56 0.7681 0.9996 1708889 ChemDiv1_011546 Cc1ccc(cc1)S(=O)CC(O)CSc2nc(C)c3CCCCc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M19 compound treatment 275.7 90.8 0.47 279.8 94.3 0.49 0.6816 0.9999 1462285 ChemDiv1_011547 CCOC(=O)c1c(CN2CCCCC2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M20 compound treatment 393.6 209.0 1.09 385.9 200.0 1.04 1.5065 0.9998 1572523 ChemDiv1_011548 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M21 compound treatment 334.6 150.0 0.78 330.0 145.0 0.75 1.0834 0.9998 1975686 ChemDiv1_011549 COC(=O)c1c(sc2CCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5ccsc5)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M22 compound treatment 375.0 190.0 0.99 373.8 188.0 0.98 1.3934 1.0 1483860 ChemDiv1_011550 CCOC(=O)c1c(CN2CCN(Cc3ccccc3)CC2)n(c4ccccc4)c5cc(Br)c(OC)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M23 mock treatment 278.9 94.0 0.49 280.0 94.5 0.49 0.6941 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 M24 mock treatment 183.0 -1.9 -0.01 186.7 1.22 0.01 -0.0025 -0.2161 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N01 compound treatment 280.7 95.8 0.5 285.3 99.8 0.52 0.7203 0.9998 1975687 ChemDiv1_011551 O=C(CSC1=C(C#N)C2(CCCCC2)C(C#N)C(=O)N1)Nc3nc4ccccc4s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N02 compound treatment 282.4 97.5 0.51 284.3 98.8 0.51 0.7229 1.0 1608225 ChemDiv1_011552 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)cc3C)c(=O)n2C1c4cc(OC)ccc4OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N03 compound treatment 279.7 94.8 0.49 282.0 96.5 0.5 0.7044 1.0 1614470 ChemDiv1_011553 COc1ccc(N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccccc4)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N04 compound treatment 283.7 98.8 0.52 278.0 92.5 0.48 0.7045 0.9994 1559628 ChemDiv1_011554 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N05 compound treatment 277.7 92.8 0.48 279.5 94.0 0.49 0.6879 1.0 1975688 ChemDiv1_011555 Cc1c(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4)cc3s2)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N06 compound treatment 276.0 91.1 0.48 282.1 96.6 0.5 0.6912 0.9996 1975689 ChemDiv1_011556 CCC(SCCSC(CC)C(=O)Nc1nnc(C)s1)C(=O)Nc2nnc(C)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N07 compound treatment 277.8 92.9 0.48 281.0 95.5 0.5 0.6938 0.9999 1975690 ChemDiv1_011557 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccs4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N08 compound treatment 283.2 98.3 0.51 286.2 101.0 0.52 0.7328 0.9999 1781699 ChemDiv1_011558 CCOC(=O)C1C(C(=C(NC1=O)SCc2ccccc2)C#N)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N09 compound treatment 278.7 93.8 0.49 282.7 97.2 0.51 0.7033 0.9999 1975691 ChemDiv1_011559 CCOc1ccc2nc(NC(=O)C3CC=CCC3C(=O)OCC(F)(F)C(F)F)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N10 compound treatment 276.6 91.7 0.48 281.3 95.8 0.5 0.6904 0.9998 1975692 ChemDiv1_011560 Cc1cccc(c1)C(=O)N2N=C(CC2(O)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N11 compound treatment 281.6 96.7 0.5 282.9 97.4 0.51 0.7148 1.0 1975693 ChemDiv1_011561 COC(=O)c1ccc(Nc2nc(C)c([N+](=O)[O-])c(Nc3ccc(cc3)C(=O)OC)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N12 compound treatment 278.8 93.9 0.49 282.3 96.8 0.5 0.7022 0.9999 1975694 ChemDiv1_011562 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N13 compound treatment 281.2 96.3 0.5 287.3 102.0 0.53 0.7295 0.9997 1975695 ChemDiv1_011563 CCOc1ccc2nc(Sc3ccc(C=C4C(=O)NC(=O)NC4=O)o3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N14 compound treatment 276.0 91.1 0.48 280.2 94.7 0.49 0.6842 0.9998 1975696 ChemDiv1_011564 Nc1ccc(cc1)C(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N15 compound treatment 283.1 98.2 0.51 286.9 101.0 0.53 0.735 0.9999 1975697 ChemDiv1_011565 [O-][N+](=O)c1ccccc1S(=O)(=O)NCCSc2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N16 compound treatment 279.7 94.8 0.49 281.6 96.1 0.5 0.703 1.0 1975698 ChemDiv1_011566 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)Nc3cccc4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N17 compound treatment 311.3 126.0 0.66 312.9 127.0 0.66 0.9346 1.0 1255865 ChemDiv1_011567 CC1SC2(N(C1=O)c3cccc(Cl)c3)C(=O)N(CN4CCCCC4)c5ccccc52 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N18 compound treatment 306.7 122.0 0.64 307.4 122.0 0.63 0.8974 1.0 1975699 ChemDiv1_011568 Clc1ccccc1NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N19 compound treatment 390.0 205.0 1.07 399.3 214.0 1.11 1.5424 0.9998 1148673 ChemDiv1_011569 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(O)cc3Br)c(=O)n2C1c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N20 compound treatment 292.4 108.0 0.56 289.9 104.0 0.54 0.7803 0.9999 1310494 ChemDiv1_011570 COc1cc(cc2sc(=O)oc12)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N21 compound treatment 345.8 161.0 0.84 345.4 160.0 0.83 1.1813 1.0 1496720 ChemDiv1_011571 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3O)c(=O)n2C1c4cc(OC)c(OC)cc4Br 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N22 compound treatment 278.8 93.9 0.49 277.8 92.3 0.48 0.6857 0.9999 1975700 ChemDiv1_011572 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)NCCOc4ccccc4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N23 mock treatment 275.1 90.2 0.47 277.9 92.4 0.48 0.6724 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 N24 mock treatment 186.3 1.4 0.01 188.9 3.42 0.02 0.0177 0.9229 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O01 compound treatment 282.2 97.3 0.51 283.8 98.3 0.51 0.7203 1.0 1975701 ChemDiv1_011573 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3ccccc3C)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O02 compound treatment 279.7 94.8 0.49 278.1 92.6 0.48 0.6901 0.9999 1975702 ChemDiv1_011574 CCCOc1ccccc1C2NC(=O)NC(=C2C(=O)OCCOc3ccccc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O03 compound treatment 280.8 95.9 0.5 282.3 96.8 0.5 0.7096 1.0 1171178 ChemDiv1_011575 CC1=C(C(=O)OCC=C)C2(C(=O)Nc3ccc(C)cc32)C(=C(N)O1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O04 compound treatment 282.0 97.1 0.51 279.7 94.2 0.49 0.7045 0.9999 1589790 ChemDiv1_011576 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O05 compound treatment 278.9 94.0 0.49 281.5 96.0 0.5 0.6996 1.0 1975703 ChemDiv1_011577 [O-][N+](=O)c1cc(Cl)ccc1NC(=O)CSc2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O06 compound treatment 280.5 95.6 0.5 280.4 94.9 0.49 0.7015 1.0 1975704 ChemDiv1_011578 NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)CN3CCCCC3)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O07 compound treatment 282.0 97.1 0.51 277.4 91.9 0.48 0.696 0.9996 1467397 ChemDiv1_011579 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccccc4F)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O08 compound treatment 278.2 93.3 0.49 283.2 97.7 0.51 0.7033 0.9998 1614923 ChemDiv1_011580 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5cc(OC)ccc5OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O09 compound treatment 283.4 98.5 0.51 279.8 94.3 0.49 0.71 0.9997 1220001 ChemDiv1_011581 CC1SC2(N(C1=O)c3cccc(F)c3)C(=O)Nc4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O10 compound treatment 284.0 99.1 0.52 280.1 94.6 0.49 0.7133 0.9997 1261609 ChemDiv1_011582 CC(C)COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O11 compound treatment 294.2 109.0 0.57 293.2 108.0 0.56 0.7991 1.0 1975705 ChemDiv1_011583 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)C(F)(F)F)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O12 compound treatment 281.3 96.4 0.5 281.7 96.2 0.5 0.7092 1.0 1975706 ChemDiv1_011584 CCSc1nc2ccccc2n1CC(=O)Nc3ccc(cc3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O13 compound treatment 279.8 94.9 0.5 282.2 96.7 0.5 0.7055 1.0 1555543 ChemDiv1_011585 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccc(Cl)cc32)C(=C(N)O1)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O14 compound treatment 283.3 98.4 0.51 282.4 96.9 0.5 0.7192 1.0 1975707 ChemDiv1_011586 COc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(OC)c(OC)c3)/S2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O15 compound treatment 284.5 99.6 0.52 286.2 101.0 0.52 0.7376 1.0 1927567 ChemDiv1_011587 CCC1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O16 compound treatment 302.9 118.0 0.62 295.5 110.0 0.57 0.8396 0.9993 1410430 ChemDiv1_011588 COc1cc(ccc1OCC#N)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O17 compound treatment 302.4 118.0 0.61 303.5 118.0 0.61 0.8672 1.0 1535801 ChemDiv1_011589 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OC)c(OC)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O18 compound treatment 278.0 93.1 0.49 275.8 90.3 0.47 0.6754 0.9999 1975708 ChemDiv1_011590 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3C)cc([N+](=O)[O-])c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O19 compound treatment 269.9 85.0 0.44 277.5 92.0 0.48 0.6517 0.9993 1975709 ChemDiv1_011591 O=C1c2ccccc2C(=O)c3cc(NS(=O)(=O)c4ccc5C(=O)c6ccccc6C(=O)c5c4)ccc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O20 compound treatment 280.3 95.4 0.5 277.9 92.4 0.48 0.6916 0.9998 1729713 ChemDiv1_011592 CCOc1cc(Br)c(C=c2sc3nc4ccccc4n3c2=O)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O21 compound treatment 285.0 100.0 0.52 287.5 102.0 0.53 0.7442 1.0 1425769 ChemDiv1_011593 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccnc3)N)c4sc5CCCCc5c4C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O22 compound treatment 277.5 92.6 0.48 275.7 90.2 0.47 0.6732 0.9999 1975710 ChemDiv1_011594 Cc1cc(C)c(C#N)c(SCc2n[nH]c3OC(=C(C#N)C(c23)c4ccc(F)cc4)N)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O23 mock treatment 281.8 96.9 0.51 275.3 89.8 0.47 0.6876 0.9992 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 O24 mock treatment 94.6 -90.3 -0.47 90.2 -95.3 -0.5 -0.6833 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P01 compound treatment 287.5 103.0 0.54 287.3 102.0 0.53 0.7527 1.0 1975711 ChemDiv1_011595 CCCCOc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P02 compound treatment 284.9 100.0 0.52 284.7 99.2 0.52 0.7335 1.0 1975712 ChemDiv1_011596 COc1ccc(cc1)C(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P03 compound treatment 283.2 98.3 0.51 283.5 98.0 0.51 0.7229 1.0 1975713 ChemDiv1_011597 CC(C)COC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc3cc(C)cc(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P04 compound treatment 280.5 95.6 0.5 284.8 99.3 0.52 0.7177 0.9999 1781700 ChemDiv1_011598 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P05 compound treatment 281.0 96.1 0.5 284.4 98.9 0.51 0.7181 0.9999 1975714 ChemDiv1_011599 Cc1c(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4Cl)cc3s2)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P06 compound treatment 283.9 99.0 0.52 279.2 93.7 0.49 0.7096 0.9996 1365022 ChemDiv1_011600 CCOc1ccc(Nc2nc(nc(n2)N3CCOCC3)N4CCOCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P07 compound treatment 284.5 99.6 0.52 275.9 90.4 0.47 0.6997 0.9987 1197385 ChemDiv1_011601 COc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)OCC=C)C)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P08 compound treatment 284.8 99.9 0.52 283.3 97.8 0.51 0.728 0.9999 1340607 ChemDiv1_011602 Cc1nc(SCC(=O)c2cc3ccccc3oc2=O)c(C#N)c(C)c1C(=O)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P09 compound treatment 291.8 107.0 0.56 292.8 107.0 0.56 0.7888 1.0 1975715 ChemDiv1_011603 COc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P10 compound treatment 335.6 151.0 0.79 333.7 148.0 0.77 1.1007 0.9999 1975716 ChemDiv1_011604 CCSc1nc2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P11 compound treatment 352.5 168.0 0.87 347.9 162.0 0.84 1.2152 0.9998 1975717 ChemDiv1_011605 CN(C)c1ccc(/C=C\2/S/C(=N/c3ccc4ccccc4c3)/NC2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P12 compound treatment 289.6 105.0 0.55 291.4 106.0 0.55 0.7755 1.0 1975718 ChemDiv1_011606 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)Nc4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P13 compound treatment 296.9 112.0 0.58 295.2 110.0 0.57 0.8164 0.9999 1734607 ChemDiv1_011607 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Cl)ccc3O)c(=O)n2C1c4ccc5OCOc5c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P14 compound treatment 284.1 99.2 0.52 283.0 97.5 0.51 0.7243 0.9999 1975719 ChemDiv1_011608 C1C(N(N=C1c2cccs2)c3nc(cs3)c4ccc5ccccc5c4)c6ccoc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P15 compound treatment 277.9 93.0 0.49 283.3 97.8 0.51 0.7026 0.9997 1645829 ChemDiv1_011609 COc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P16 compound treatment 286.6 102.0 0.53 283.7 98.2 0.51 0.7361 0.9998 1695372 ChemDiv1_011610 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NC3CCCCCC3)OCc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P17 compound treatment 277.9 93.0 0.49 279.7 94.2 0.49 0.6893 1.0 1557456 ChemDiv1_011611 COc1ccccc1Nc2nc3nonc3nc2N4CCC(C)CC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P18 compound treatment 280.1 95.2 0.5 285.8 100.0 0.52 0.7199 0.9997 1975720 ChemDiv1_011612 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccccc3Cl)c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P19 compound treatment 294.5 110.0 0.57 292.3 107.0 0.56 0.7969 0.9999 1975721 ChemDiv1_011613 O=C(Oc1ccc(NC2=NS(=O)(=O)c3ccccc23)cc1CN4CCCCC4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P20 compound treatment 277.0 92.1 0.48 282.1 96.6 0.5 0.6948 0.9998 1177064 ChemDiv1_011614 COc1cc(cc(OC)c1OCc2ccc(Cl)c(Cl)c2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P21 compound treatment 278.8 93.9 0.49 281.1 95.6 0.5 0.6978 1.0 1975722 ChemDiv1_011615 CC1SC2(N(C1=O)c3ccc(Cl)c(Cl)c3)C(=O)Nc4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P22 compound treatment 294.1 109.0 0.57 289.8 104.0 0.54 0.7862 0.9997 1975723 ChemDiv1_011616 CCOC(=O)c1cnn(c1NC(=O)CSc2nc3ccccc3[nH]2)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P23 mock treatment 276.8 91.9 0.48 281.4 95.9 0.5 0.6915 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.619 P24 mock treatment 78.9 -106.0 -0.55 95.3 -90.2 -0.47 -0.7225 -0.9966 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A01 compound treatment 287.2 99.8 0.52 280.7 97.4 0.51 0.7262 0.9999 1496956 ChemDiv1_011617 Clc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cc6cc(Br)ccc6o5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A02 compound treatment 284.3 96.9 0.51 277.2 93.9 0.49 0.7026 0.9999 1945441 ChemDiv1_011618 CCCC1=NN(C(=O)Cc2ccc(OC)c(OC)c2)C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A03 compound treatment 283.9 96.5 0.5 277.8 94.5 0.49 0.7033 0.9999 1975724 ChemDiv1_011619 COc1ccc(cc1)C(=O)OCCN(C2=NS(=O)(=O)c3ccccc23)c4cccc(C)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A04 compound treatment 288.5 101.0 0.53 279.8 96.5 0.5 0.7277 0.9997 1975725 ChemDiv1_011620 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccc5OCOc5c4)c6cccs6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A05 compound treatment 282.6 95.2 0.5 276.0 92.7 0.48 0.6919 0.9999 1932920 ChemDiv1_011621 COc1cc(ccc1OCc2cc3OCOc3cc2Cl)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A06 compound treatment 282.0 94.6 0.49 276.1 92.8 0.48 0.6901 0.9999 1975726 ChemDiv1_011622 [O-][N+](=O)c1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(F)c(F)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A07 compound treatment 281.0 93.6 0.49 278.3 95.0 0.49 0.6945 1.0 1975727 ChemDiv1_011623 CC(=O)/N=C\1/NC(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3Cl)/S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A08 compound treatment 280.8 93.4 0.49 275.3 92.0 0.48 0.6827 1.0 1975728 ChemDiv1_011624 CCCCCOc1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A09 compound treatment 279.6 92.2 0.48 272.9 89.6 0.47 0.6695 0.9999 1975729 ChemDiv1_011625 CC(C)OC(=O)C1=C(C)OC(=C(C#N)C1c2cccnc2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A10 compound treatment 278.3 90.9 0.47 272.4 89.1 0.46 0.6628 0.9999 1975730 ChemDiv1_011626 COc1ccc(OCC(CN(C)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(OC)cc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A11 compound treatment 284.4 97.0 0.51 275.5 92.2 0.48 0.6967 0.9996 1574144 ChemDiv1_011627 CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(Cc3ccccc3)c4cc(Br)c(O)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A12 compound treatment 283.0 95.6 0.5 271.1 87.8 0.46 0.6754 0.999 1610779 ChemDiv1_011628 Clc1ccc(cc1Cl)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A13 compound treatment 283.0 95.6 0.5 276.2 92.9 0.48 0.6941 0.9999 1169058 ChemDiv1_011629 Cc1nnc(SCC(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A14 compound treatment 284.4 97.0 0.51 273.1 89.8 0.47 0.6879 0.9992 1975731 ChemDiv1_011630 COc1cc(cc(OC)c1OC)C(=O)N2CCN(CC2)C3=NS(=O)(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A15 compound treatment 278.8 91.4 0.48 275.5 92.2 0.48 0.6761 1.0 1975732 ChemDiv1_011631 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccccc3[N+](=O)[O-])c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A16 compound treatment 283.3 95.9 0.5 276.1 92.8 0.48 0.6949 0.9998 1250464 ChemDiv1_011632 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)c4cccc(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A17 compound treatment 285.1 97.7 0.51 274.6 91.3 0.47 0.696 0.9994 1717010 ChemDiv1_011633 OC(CSc1nc(cc(c1C#N)c2ccccc2)c3ccccc3)CN4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A18 compound treatment 281.4 94.0 0.49 275.3 92.0 0.48 0.6849 0.9999 1975733 ChemDiv1_011634 Cc1ccnc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C4CCCCC4C3=O)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A19 compound treatment 281.6 94.2 0.49 271.5 88.2 0.46 0.6717 0.9994 1429163 ChemDiv1_011635 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccc(Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A20 compound treatment 275.9 88.5 0.46 273.3 90.0 0.47 0.6573 1.0 1975734 ChemDiv1_011636 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)/C=C/c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A21 compound treatment 279.4 92.0 0.48 272.8 89.5 0.47 0.6684 0.9999 1169790 ChemDiv1_011637 Fc1ccc(cc1F)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A22 compound treatment 280.3 92.9 0.48 274.0 90.7 0.47 0.6761 0.9999 1265866 ChemDiv1_011638 CC1SC2(N(C1=O)c3ccc(C)c(Cl)c3)C(=O)Nc4ccccc42 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A23 mock treatment 280.6 93.2 0.49 272.4 89.1 0.46 0.6713 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 A24 mock treatment 76.6 -111.0 -0.58 77.3 -106.0 -0.55 -0.7983 -0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B01 compound treatment 285.8 98.4 0.51 280.4 97.1 0.5 0.7199 1.0 1125898 ChemDiv1_011639 CC1(C)CC(=O)c2sc(NC(=O)CSc3nc4ccccc4[nH]3)nc2C1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B02 compound treatment 285.7 98.3 0.51 282.9 99.6 0.52 0.7287 1.0 1975735 ChemDiv1_011640 Fc1ccccc1Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B03 compound treatment 292.1 105.0 0.55 288.5 105.0 0.55 0.7729 1.0 1975736 ChemDiv1_011641 Nc1nc(SCC(=O)c2ccc(O)c(O)c2)c(C#N)c(c1C#N)c3cccc(Cl)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B04 compound treatment 284.0 96.6 0.5 274.6 91.3 0.47 0.692 0.9996 1300987 ChemDiv1_011642 Brc1ccc(cc1)N2C(=O)CSC23C(=O)N(CN4CCN(Cc5ccccc5)CC4)c6ccccc63 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B05 compound treatment 282.2 94.8 0.49 277.7 94.4 0.49 0.6967 1.0 1975737 ChemDiv1_011643 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(Br)cc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B06 compound treatment 283.4 96.0 0.5 280.7 97.4 0.51 0.7122 1.0 1415944 ChemDiv1_011644 CCOC(=O)c1c(CN2CCC(CC2)(C(=O)OCC)c3ccccc3)n(Cc4ccccc4)c5cc(Br)c(O)cc15 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B07 compound treatment 278.4 91.0 0.47 279.2 95.9 0.5 0.6882 0.9997 1731250 ChemDiv1_011645 Cn1cnnc1SCC(=O)Nc2ccc3nc(SCC(=O)NC4CCCCC4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B08 compound treatment 280.7 93.3 0.49 279.6 96.3 0.5 0.6982 0.9999 1975738 ChemDiv1_011646 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NC(C)C)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B09 compound treatment 285.5 98.1 0.51 281.4 98.1 0.51 0.7225 1.0 1975739 ChemDiv1_011647 Cc1ccc(NC(=O)c2c(C)nc(S)c(C#N)c2c3cccs3)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B10 compound treatment 279.6 92.2 0.48 277.0 93.7 0.49 0.6845 1.0 1975740 ChemDiv1_011648 Cc1sc2nc(oc(=O)c2c1C)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B11 compound treatment 280.4 93.0 0.48 278.9 95.6 0.5 0.6945 0.9999 1617551 ChemDiv1_011649 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(SC)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B12 compound treatment 283.6 96.2 0.5 275.4 92.1 0.48 0.6934 0.9997 1975741 ChemDiv1_011650 NNc1nc(Nc2ccccc2[N+](=O)[O-])nc(OC(C(F)(F)F)C(F)(F)F)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B13 compound treatment 275.2 87.8 0.46 279.2 95.9 0.5 0.6764 0.9991 1415881 ChemDiv1_011651 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2Cl)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B14 compound treatment 280.7 93.3 0.49 276.2 92.9 0.48 0.6857 1.0 1975742 ChemDiv1_011652 CCC(=O)Nc1ccc2nc(SCc3cc(ccc3OC)[N+](=O)[O-])sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B15 compound treatment 281.8 94.4 0.49 277.1 93.8 0.49 0.693 1.0 1640880 ChemDiv1_011653 CCOC(=O)c1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B16 compound treatment 280.4 93.0 0.48 277.2 93.9 0.49 0.6882 1.0 1781290 ChemDiv1_011654 CC1CC(N(C(=O)c2ccc(Cl)cc2Cl)c3ccccc3)c4ccccc4N1C(=O)c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B17 compound treatment 278.4 91.0 0.47 276.2 92.9 0.48 0.6772 1.0 1204897 ChemDiv1_011655 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5cccc(F)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B18 compound treatment 278.5 91.1 0.48 277.3 94.0 0.49 0.6816 0.9999 1204933 ChemDiv1_011656 CC1(COC2(OC1)C(=O)N(CN3CCOCC3)c4ccccc42)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B19 compound treatment 280.6 93.2 0.49 272.6 89.3 0.46 0.6721 0.9997 1615271 ChemDiv1_011657 COc1ccccc1N2C(=O)c3ccccc3NC24C(=O)N(Cc5c(Cl)cccc5Cl)c6ccccc64 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B20 compound treatment 280.5 93.1 0.49 274.3 91.0 0.47 0.6779 0.9999 1975743 ChemDiv1_011658 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC)cc3CSc4ccccn4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B21 compound treatment 276.5 89.1 0.46 274.9 91.6 0.48 0.6654 0.9999 1975744 ChemDiv1_011659 Clc1cccc(Cl)c1CN2C(=O)C3(Nc4sc5CCCCc5c4C(=O)N3CCc6ccccc6)c7ccccc27 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B22 compound treatment 277.1 89.7 0.47 271.4 88.1 0.46 0.6547 0.9999 1732080 ChemDiv1_011660 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5ccccc5)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B23 mock treatment 280.4 93.0 0.48 275.6 92.3 0.48 0.6823 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 B24 mock treatment 76.9 -111.0 -0.58 75.7 -108.0 -0.56 -0.803 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C01 compound treatment 288.1 101.0 0.53 281.0 97.7 0.51 0.7306 0.9999 1975745 ChemDiv1_011661 CCC(=O)Oc1ccc(/C=C\2/C(=NN(C2=O)c3cccc(Br)c3)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C02 compound treatment 282.2 94.8 0.49 276.7 93.4 0.49 0.693 1.0 1975746 ChemDiv1_011662 COc1ccc(CC(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C03 compound treatment 290.2 103.0 0.54 277.7 94.4 0.49 0.7262 0.999 1531497 ChemDiv1_011663 CC(C)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)CSc4nnnn4C)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C04 compound treatment 283.4 96.0 0.5 279.2 95.9 0.5 0.7066 1.0 1455557 ChemDiv1_011664 COc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)c(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C05 compound treatment 284.5 97.1 0.51 277.0 93.7 0.49 0.7026 0.9998 1975747 ChemDiv1_011665 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cn(Cc5ccc(Cl)c(Cl)c5)nc4c6ccccc6)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C06 compound treatment 284.6 97.2 0.51 276.5 93.2 0.48 0.7011 0.9997 1147089 ChemDiv1_011666 Brc1ccc2oc(cc2c1)C(=O)N3CCc4c(C3)[nH]c5ccccc45 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C07 compound treatment 286.5 99.1 0.52 277.6 94.3 0.49 0.7122 0.9997 1220515 ChemDiv1_011667 COc1cc(cc(OC)c1OC(=O)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C08 compound treatment 283.2 95.8 0.5 277.1 93.8 0.49 0.6982 0.9999 1975748 ChemDiv1_011668 Cc1cc2nc3sc(=Cc4cn(Cc5ccccc5F)c6ccccc46)c(=O)n3c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C09 compound treatment 330.3 143.0 0.75 319.6 136.0 0.71 1.0281 0.9997 1975749 ChemDiv1_011669 Clc1ccc(Cn2cc(/C=C/3\SC(=N)NC3=O)c4ccccc24)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C10 compound treatment 296.3 109.0 0.57 284.7 101.0 0.53 0.7744 0.9993 1975750 ChemDiv1_011670 COc1ccc(/C=C/2\S\C(=N\c3cccc4ccccc34)\NC2=O)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C11 compound treatment 287.0 99.6 0.52 285.7 102.0 0.53 0.7438 0.9999 1646097 ChemDiv1_011671 O=C(CSc1nc2ccccc2s1)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C12 compound treatment 279.6 92.2 0.48 277.9 94.6 0.49 0.6879 0.9999 1146046 ChemDiv1_011672 Clc1ccc(cc1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C13 compound treatment 278.4 91.0 0.47 278.7 95.4 0.5 0.6864 0.9998 1688121 ChemDiv1_011673 COc1ccccc1NC(=O)CSc2nc3ccc(NC(=O)CSc4nncn4C)cc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C14 compound treatment 280.3 92.9 0.48 273.2 89.9 0.47 0.6732 0.9998 1149509 ChemDiv1_011674 CCOC(=O)c1c(CN2CCN(CCO)CC2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C15 compound treatment 291.6 104.0 0.54 291.2 108.0 0.56 0.781 0.9999 1975751 ChemDiv1_011675 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc(C)c(C)c3)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C16 compound treatment 276.3 88.9 0.46 273.2 89.9 0.47 0.6584 1.0 1263179 ChemDiv1_011676 COc1ccc2oc(C)c(C(=O)c3oc4ccccc4c3N)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C17 compound treatment 280.5 93.1 0.49 273.9 90.6 0.47 0.6765 0.9999 1238089 ChemDiv1_011677 Cc1nc2sc(C#N)c(N)c2c(C)c1CC(=O)c3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C18 compound treatment 278.7 91.3 0.48 271.3 88.0 0.46 0.6603 0.9998 1559227 ChemDiv1_011678 O=C(CSc1ccccn1)N2CCN(CC2)C(=O)CSc3ccccn3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C19 compound treatment 281.1 93.7 0.49 275.6 92.3 0.48 0.6849 1.0 1496776 ChemDiv1_011679 Cc1ccc2c(N)c(sc2n1)C(=O)c3ccc(cc3)C(=O)c4sc5nc(C)ccc5c4N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C20 compound treatment 268.5 81.1 0.42 261.9 78.6 0.41 0.5881 0.9999 1975752 ChemDiv1_011680 CCc1ccc2NC(=O)C3(NN=C(S3)c4ccc(C)cc4)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C21 compound treatment 280.9 93.5 0.49 272.7 89.4 0.46 0.6735 0.9997 1227832 ChemDiv1_011681 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C22 compound treatment 278.9 91.5 0.48 274.7 91.4 0.48 0.6735 1.0 1342902 ChemDiv1_011682 CCOc1ccc(NC(=O)Cn2c(SCC)nc3ccccc23)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C23 mock treatment 279.4 92.0 0.48 276.1 92.8 0.48 0.6805 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 C24 mock treatment 82.3 -105.0 -0.55 78.0 -105.0 -0.55 -0.7747 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D01 compound treatment 282.4 95.0 0.5 278.7 95.4 0.5 0.7011 1.0 1220149 ChemDiv1_011683 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D02 compound treatment 286.1 98.7 0.51 278.4 95.1 0.49 0.7137 0.9998 1609886 ChemDiv1_011684 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D03 compound treatment 285.3 97.9 0.51 278.5 95.2 0.5 0.7111 0.9999 1405796 ChemDiv1_011685 CC(C)Cc1c(C#N)c(SCC(=O)c2ccc(O)c(O)c2)nc(C)c1C(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D04 compound treatment 284.9 97.5 0.51 273.1 89.8 0.47 0.6898 0.9991 1353902 ChemDiv1_011686 CC(=O)Nc1ccc2nc(SCC(=O)N3CCc4ccccc34)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D05 compound treatment 284.7 97.3 0.51 283.5 100.0 0.52 0.7272 0.9999 1975753 ChemDiv1_011687 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4ccc(Br)cc4F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D06 compound treatment 281.8 94.4 0.49 282.3 99.0 0.51 0.7121 0.9997 1166738 ChemDiv1_011688 CCOC(=O)c1c(CN2CCCCC2)n(c3ccccc3)c4cc(Br)c(O)c(CN5CCOCC5)c14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D07 compound treatment 285.6 98.2 0.51 281.3 98.0 0.51 0.7225 1.0 1509110 ChemDiv1_011689 O=C(CSc1nc2ccc(NC(=O)CSc3nnnn3Cc4ccccc4)cc2s1)Nc5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D08 compound treatment 282.6 95.2 0.5 280.6 97.3 0.51 0.7088 1.0 1943170 ChemDiv1_011690 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCc4ccco4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D09 compound treatment 283.4 96.0 0.5 280.4 97.1 0.5 0.7111 1.0 1975754 ChemDiv1_011691 CCCC1=C(C(C(=C(N)O1)C#N)c2ccc(OC)c(CSc3ccccn3)c2)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D10 compound treatment 286.5 99.1 0.52 279.5 96.2 0.5 0.7192 0.9999 1975755 ChemDiv1_011692 Cc1sc2nc(oc(=O)c2c1C)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D11 compound treatment 283.9 96.5 0.5 272.4 89.1 0.46 0.6835 0.9991 1975756 ChemDiv1_011693 Cc1ccsc1C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)S(=O)(=O)N)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D12 compound treatment 281.9 94.5 0.49 276.6 93.3 0.49 0.6916 1.0 1975757 ChemDiv1_011694 COc1cc([N+](=O)[O-])c(Cl)cc1N/C=C\2/C(=NN(C2=O)c3cccc(Cl)c3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D13 compound treatment 286.5 99.1 0.52 282.3 99.0 0.51 0.7295 1.0 1975758 ChemDiv1_011695 CC(C)OC(=O)CC(=O)CSc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D14 compound treatment 281.6 94.2 0.49 276.9 93.6 0.49 0.6916 1.0 1975759 ChemDiv1_011696 CCCCCOc1ccc(cc1)N2C(=O)CSC23C(=O)N(CN4CCC(Cc5ccccc5)CC4)c6ccccc63 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D15 compound treatment 282.3 94.9 0.49 276.8 93.5 0.49 0.6938 1.0 1975760 ChemDiv1_011697 Fc1ccccc1CN2C(=O)C3(Nc4ccccc4C(=O)N3c5cccc(c5)C(F)(F)F)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D16 compound treatment 279.6 92.2 0.48 273.7 90.4 0.47 0.6724 0.9999 1391729 ChemDiv1_011698 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCN(CC4)c5ccc(F)cc5)c6ccccc63 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D17 compound treatment 276.1 88.7 0.46 274.8 91.5 0.48 0.6635 0.9999 1942832 ChemDiv1_011699 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)/C=C/c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D18 compound treatment 279.9 92.5 0.48 277.0 93.7 0.49 0.6856 1.0 1438364 ChemDiv1_011700 Cc1cc2nc3sc(=Cc4cccc(OCc5c(F)cccc5Cl)c4)c(=O)n3c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D19 compound treatment 282.7 95.3 0.5 276.4 93.1 0.48 0.6938 0.9999 1975761 ChemDiv1_011701 Cc1n[nH]c2OC(=C(C#N)C(c12)c3ccccc3OCc4cccc(Br)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D20 compound treatment 280.7 93.3 0.49 275.2 91.9 0.48 0.682 1.0 1975762 ChemDiv1_011702 CCCc1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccccc43)c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D21 compound treatment 282.4 95.0 0.5 276.3 93.0 0.48 0.6923 0.9999 1288456 ChemDiv1_011703 CCOC(=O)C1=C(N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc5OCOc5c4)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D22 compound treatment 273.6 86.2 0.45 275.1 91.8 0.48 0.6554 0.9995 1650569 ChemDiv1_011704 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4ccc(OC(=O)N5CCOCC5)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D23 mock treatment 281.8 94.4 0.49 274.5 91.2 0.47 0.6835 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 D24 mock treatment 79.0 -108.0 -0.57 75.2 -108.0 -0.56 -0.7971 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E01 compound treatment 288.7 101.0 0.53 282.5 99.2 0.52 0.7383 0.9999 1975763 ChemDiv1_011705 CCC(=O)Oc1ccc(/C=C\2/C(=NN(C2=O)c3cccc(c3)C(F)(F)F)C)cc1OC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E02 compound treatment 286.3 98.9 0.52 282.1 98.8 0.51 0.728 1.0 1975764 ChemDiv1_011706 OC1(CC(=NN1C(=O)c2cccc(Br)c2)C(F)(F)F)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E03 compound treatment 304.5 117.0 0.61 296.5 113.0 0.59 0.8481 0.9998 1478562 ChemDiv1_011707 COc1cc(C=c2sc3nc4c(C)c(C)ccc4n3c2=O)cc(OC)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E04 compound treatment 286.9 99.5 0.52 282.9 99.6 0.52 0.7332 1.0 1253426 ChemDiv1_011708 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccccc4)c5cccs5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E05 compound treatment 282.9 95.5 0.5 281.9 98.6 0.51 0.7147 0.9999 1975765 ChemDiv1_011709 O=C(CSc1nc2ccc(NC(=O)/C=C/c3ccccc3)cc2s1)NCC4CCCO4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E06 compound treatment 283.4 96.0 0.5 276.8 93.5 0.49 0.6978 0.9999 1117911 ChemDiv1_011710 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3sc4CCCCc4c3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E07 compound treatment 347.5 160.0 0.84 334.9 152.0 0.79 1.1478 0.9996 1975766 ChemDiv1_011711 CCOc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(Cl)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E08 compound treatment 282.9 95.5 0.5 277.0 93.7 0.49 0.6967 0.9999 1975767 ChemDiv1_011712 [O-][N+](=O)c1ccc(cc1)C2C(=C3NC(=O)c4c5CCCCc5sc4N3C6=C2C(=O)CCC6)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E09 compound treatment 287.0 99.6 0.52 277.5 94.2 0.49 0.7137 0.9996 1151059 ChemDiv1_011713 Cc1nc(cs1)c2cccc(NC(=O)c3cc4cc(Br)ccc4oc3=O)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E10 compound treatment 283.1 95.7 0.5 274.1 90.8 0.47 0.6868 0.9996 1491087 ChemDiv1_011714 CCSc1nc(N)c2c3CCN(Cc4ccccc4)Cc3sc2n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E11 compound treatment 286.8 99.4 0.52 277.3 94.0 0.49 0.7122 0.9996 1700724 ChemDiv1_011715 O=C(CSCC(=O)Nc1ccc2nc(SCC(=O)N3CCOCC3)sc2c1)Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E12 compound treatment 284.0 96.6 0.5 279.6 96.3 0.5 0.7103 1.0 1736969 ChemDiv1_011716 COc1ccccc1N2CCN(Cc3cc(Br)c(O)c4ncccc34)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E13 compound treatment 280.6 93.2 0.49 277.8 94.5 0.49 0.6912 1.0 1257341 ChemDiv1_011717 Cc1cc2nc3sc(=Cc4cc(Cl)ccc4OCc5c(F)cccc5Cl)c(=O)n3c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E14 compound treatment 285.8 98.4 0.51 277.6 94.3 0.49 0.7096 0.9997 1509756 ChemDiv1_011718 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4cc(Br)c(OC(=O)C)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E15 compound treatment 280.0 92.6 0.48 273.9 90.6 0.47 0.6746 0.9999 1593480 ChemDiv1_011719 CCOc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)ccc1OCc5ccccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E16 compound treatment 280.4 93.0 0.48 273.3 90.0 0.47 0.6739 0.9998 1365393 ChemDiv1_011720 COC(=O)COc1cccc(c1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E17 compound treatment 283.6 96.2 0.5 276.8 93.5 0.49 0.6986 0.9999 1356645 ChemDiv1_011721 CCOC(=O)c1c(CSc2ccccc2)n(C)c3ccc(O)c(CN4CCOCC4)c13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E18 compound treatment 274.9 87.5 0.46 276.7 93.4 0.49 0.6661 0.9995 1360647 ChemDiv1_011722 COC(=O)CC(=O)Nc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E19 compound treatment 284.5 97.1 0.51 280.6 97.3 0.51 0.7158 1.0 1226850 ChemDiv1_011723 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccc(Br)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E20 compound treatment 276.7 89.3 0.47 271.8 88.5 0.46 0.6547 1.0 1488239 ChemDiv1_011724 CCC(=O)Nc1ccc2nc(SCC(=O)NCC3CCCO3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E21 compound treatment 279.7 92.3 0.48 273.4 90.1 0.47 0.6717 0.9999 1975768 ChemDiv1_011725 O=C(Oc1cc2oc3ccccc3[nH]c2c4c(=O)c5ccccc5c(=O)c14)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E22 compound treatment 273.8 86.4 0.45 274.4 91.1 0.47 0.6536 0.9997 1975769 ChemDiv1_011726 [O-][N+](=O)c1ccc(cc1)N2CCN(CN3C(=O)C4(SCC(=O)N4c5cccc(Cl)c5)c6ccccc36)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E23 mock treatment 280.7 93.3 0.49 273.7 90.4 0.47 0.6765 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 E24 mock treatment 79.1 -108.0 -0.57 73.0 -110.0 -0.57 -0.8049 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F01 compound treatment 287.9 100.0 0.52 277.8 94.5 0.49 0.7181 0.9995 1132732 ChemDiv1_011727 COc1ccc2oc(C(=O)c3ccc(Cl)cc3)c(N)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F02 compound treatment 290.3 103.0 0.54 282.8 99.5 0.52 0.7453 0.9998 1975770 ChemDiv1_011728 Cc1ccc2c(nc3sc(=Cc4cn(Cc5ccccc5)c6ccccc46)c(=O)n32)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F03 compound treatment 288.9 101.0 0.53 281.8 98.5 0.51 0.7365 0.9999 1975771 ChemDiv1_011729 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F04 compound treatment 286.4 99.0 0.52 275.8 92.5 0.48 0.7052 0.9994 1449252 ChemDiv1_011730 CCOC(=O)C1CCN(CN2C(=O)C3(SCC(=O)N3c4ccc(C)c(Cl)c4)c5ccccc25)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F05 compound treatment 283.1 95.7 0.5 279.6 96.3 0.5 0.707 1.0 1708230 ChemDiv1_011731 CCN(CC)C(=O)CSc1nc2ccccc2n1C(=O)NC3CCCCC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F06 compound treatment 285.7 98.3 0.51 280.3 97.0 0.5 0.7192 1.0 1613231 ChemDiv1_011732 COC(=O)c1sc2nc(N)c(C#N)c(c3ccc(OC)c(OC)c3)c2c1N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F07 compound treatment 281.1 93.7 0.49 278.3 95.0 0.49 0.6949 1.0 1138679 ChemDiv1_011733 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCC(=O)NC4CCCCC4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F08 compound treatment 283.1 95.7 0.5 279.8 96.5 0.5 0.7077 1.0 1944683 ChemDiv1_011734 Brc1ccc2nc(nc(c3ccccc3)c2c1)N4CCNCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F09 compound treatment 282.5 95.1 0.5 277.5 94.2 0.49 0.6971 1.0 1575700 ChemDiv1_011735 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)CCC4CCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F10 compound treatment 280.8 93.4 0.49 279.1 95.8 0.5 0.6967 0.9999 1975772 ChemDiv1_011736 CCOC(=O)c1c(CBr)n(C)c2cc(Br)c(OC(=O)C)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F11 compound treatment 282.1 94.7 0.49 280.6 97.3 0.51 0.707 0.9999 1975773 ChemDiv1_011737 CC1CCN(CN2C(=O)/C(=C\c3ccccc3Cl)/SC2=S)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F12 compound treatment 290.0 103.0 0.54 278.4 95.1 0.49 0.7281 0.9992 1975774 ChemDiv1_011738 COc1cc(SC#N)ccc1N/C=C\2/C(=NN(C2=O)c3ccc(Br)cc3)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F13 compound treatment 283.0 95.6 0.5 278.1 94.8 0.49 0.7011 1.0 1588761 ChemDiv1_011739 O=C(CSC1=C(C#N)C2(CCCCC2)C(C#N)C(=O)N1)C3(CC4CC5CC(C4)C3)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F14 compound treatment 284.5 97.1 0.51 273.8 90.5 0.47 0.6909 0.9993 1553268 ChemDiv1_011740 Cc1ccc(cc1Br)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F15 compound treatment 281.7 94.3 0.49 279.5 96.2 0.5 0.7015 1.0 1975775 ChemDiv1_011741 CCCC1=C(C(C(=C(N)O1)C#N)c2c(C)nn(c2Cl)c3ccccc3)C(=O)OCC 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F16 compound treatment 280.8 93.4 0.49 276.8 93.5 0.49 0.6882 1.0 1975776 ChemDiv1_011742 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCc5ccccc5C4)c6ccccc63 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F17 compound treatment 281.4 94.0 0.49 275.4 92.1 0.48 0.6853 0.9999 1426707 ChemDiv1_011743 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccc(Cl)c(Cl)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F18 compound treatment 285.0 97.6 0.51 281.7 98.4 0.51 0.7217 1.0 1655342 ChemDiv1_011744 CCOc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)ccc1OCc5ccc(F)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F19 compound treatment 279.5 92.1 0.48 276.2 92.9 0.48 0.6812 1.0 1403965 ChemDiv1_011745 CCOC(=O)C1=C(N)Oc2c(C1c3ccc(Cl)c(Cl)c3)c(=O)oc4ccccc24 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F20 compound treatment 282.4 95.0 0.5 275.0 91.7 0.48 0.6875 0.9998 1975777 ChemDiv1_011746 CC(C)(C)c1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccc(Br)cc43)c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F21 compound treatment 281.0 93.6 0.49 273.7 90.4 0.47 0.6776 0.9998 1196561 ChemDiv1_011747 CCOC(=O)C1=C(N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc(OC)c(OC)c4)c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F22 compound treatment 281.4 94.0 0.49 272.7 89.4 0.46 0.6754 0.9996 1431776 ChemDiv1_011748 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)c(OCC)c3)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F23 mock treatment 279.5 92.1 0.48 276.3 93.0 0.48 0.6816 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 F24 mock treatment 80.1 -107.0 -0.56 72.4 -111.0 -0.58 -0.8034 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G01 compound treatment 289.7 102.0 0.53 284.8 102.0 0.53 0.7505 1.0 1198349 ChemDiv1_011749 Clc1ccc(cc1Cl)C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G02 compound treatment 288.3 101.0 0.53 282.3 99.0 0.51 0.7361 0.9999 1975778 ChemDiv1_011750 Clc1ccc(OCC(=O)NN2C(=O)C3C4C=CC(C3C2=O)C54CC5)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G03 compound treatment 283.4 96.0 0.5 279.3 96.0 0.5 0.707 1.0 1469692 ChemDiv1_011751 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G04 compound treatment 282.8 95.4 0.5 277.2 93.9 0.49 0.6971 1.0 1975779 ChemDiv1_011752 [O-][N+](=O)c1ccc(cc1)C2NCCc3c2[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G05 compound treatment 285.9 98.5 0.51 281.4 98.1 0.51 0.724 1.0 1565551 ChemDiv1_011753 Nc1ccc2nc(SCC(=O)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G06 compound treatment 284.2 96.8 0.5 281.9 98.6 0.51 0.7195 1.0 1975780 ChemDiv1_011754 COc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G07 compound treatment 285.5 98.1 0.51 282.5 99.2 0.52 0.7265 1.0 1942681 ChemDiv1_011755 Cc1ccc2c(nc3sc(=Cc4ccc(o4)c5cccc(c5)C(F)(F)F)c(=O)n32)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G08 compound treatment 289.2 102.0 0.53 275.9 92.6 0.48 0.7159 0.9988 1299334 ChemDiv1_011756 CCCCc1ccc(C#N)c(SCc2c(C(=O)OCC)c3cc(OC(=O)C)c(Br)cc3n2C)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G09 compound treatment 285.2 97.8 0.51 278.7 95.4 0.5 0.7114 0.9999 1595176 ChemDiv1_011757 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCC(=O)Nc5cc(C)ccc5C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G10 compound treatment 288.4 101.0 0.53 279.9 96.6 0.5 0.7277 0.9997 1879066 ChemDiv1_011758 Clc1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G11 compound treatment 280.7 93.3 0.49 277.9 94.6 0.49 0.6919 1.0 1975781 ChemDiv1_011759 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3ccccn3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G12 compound treatment 283.1 95.7 0.5 278.5 95.2 0.5 0.703 1.0 1853273 ChemDiv1_011760 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(cc4)[N+](=O)[O-])c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G13 compound treatment 316.7 129.0 0.67 316.1 133.0 0.69 0.9651 0.9999 1629609 ChemDiv1_011761 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc(OC)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G14 compound treatment 282.0 94.6 0.49 276.9 93.6 0.49 0.693 1.0 1674300 ChemDiv1_011762 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4cc(Br)c(O)cc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G15 compound treatment 284.9 97.5 0.51 276.9 93.6 0.49 0.7037 0.9998 1950280 ChemDiv1_011763 COc1ccccc1NC(=O)CSc2nnc(NC(=O)CSc3nnc4n(N)cnn34)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G16 compound treatment 285.9 98.5 0.51 277.2 93.9 0.49 0.7085 0.9997 1224819 ChemDiv1_011764 CC(C)(C)NC(=O)CSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G17 compound treatment 281.3 93.9 0.49 276.9 93.6 0.49 0.6904 1.0 1975782 ChemDiv1_011765 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CN3CC(=O)NC(=O)C3)cc2)n1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G18 compound treatment 284.1 96.7 0.5 277.9 94.6 0.49 0.7044 0.9999 1975783 ChemDiv1_011766 [O-][N+](=O)c1cccc(NC(=O)CSc2nn3c(SCC(=O)Nc4cccc(c4)[N+](=O)[O-])nnc3s2)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G19 compound treatment 282.2 94.8 0.49 279.0 95.7 0.5 0.7015 1.0 1975784 ChemDiv1_011767 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(Br)s2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G20 compound treatment 281.1 93.7 0.49 278.3 95.0 0.49 0.6949 1.0 1975785 ChemDiv1_011768 Clc1ccc(cc1)c2nn(cc2C=c3sc4nc5ccccc5n4c3=O)c6ccccc6 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G21 compound treatment 280.2 92.8 0.48 276.0 92.7 0.48 0.6831 1.0 1975786 ChemDiv1_011769 Clc1ccc2[nH]c3c(cc(Nc4ccccc4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G22 compound treatment 277.5 90.1 0.47 271.7 88.4 0.46 0.6573 0.9999 1975787 ChemDiv1_011770 Brc1ccc(NC(=O)CSc2nnc(NC(=O)CN3CCCCC3)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G23 mock treatment 282.0 94.6 0.49 278.7 95.4 0.5 0.6996 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 G24 mock treatment 77.2 -110.0 -0.58 77.0 -106.0 -0.55 -0.7972 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H01 compound treatment 285.0 97.6 0.51 276.7 93.4 0.49 0.7034 0.9997 1546956 ChemDiv1_011771 COc1cc(ccc1OC(=O)Nc2cccc(Cl)c2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H02 compound treatment 288.7 101.0 0.53 285.0 102.0 0.53 0.7475 1.0 1975788 ChemDiv1_011772 CC(=O)/N=C/1\S/C(=C\c2cccc(F)c2)/C(=O)N1c3ccc(C)c(C)c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H03 compound treatment 281.0 93.6 0.49 276.7 93.4 0.49 0.6886 1.0 1975789 ChemDiv1_011773 Clc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H04 compound treatment 284.7 97.3 0.51 281.0 97.7 0.51 0.7181 1.0 1975790 ChemDiv1_011774 Clc1cccc(Cl)c1CN2C(=O)C3(Nc4ccccc4C(=O)N3c5ccccc5)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H05 compound treatment 280.5 93.1 0.49 277.8 94.5 0.49 0.6908 1.0 1975791 ChemDiv1_011775 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cc(ccc4C)[N+](=O)[O-])C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H06 compound treatment 287.1 99.7 0.52 281.1 97.8 0.51 0.7273 0.9999 1327630 ChemDiv1_011776 CC1CCc2c(C1)sc3nc(C)oc(=O)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H07 compound treatment 290.5 103.0 0.54 280.0 96.7 0.5 0.7358 0.9994 1403060 ChemDiv1_011777 CCSc1nnc(NC(=O)CSc2nnc3c4cc(Br)ccc4n(C)c3n2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H08 compound treatment 285.6 98.2 0.51 276.8 93.5 0.49 0.7059 0.9997 1975792 ChemDiv1_011778 CC(=O)c1ccc(NC(=O)CSc2nnc(SCC(=O)Nc3ccc(cc3)C(=O)C)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H09 compound treatment 281.9 94.5 0.49 280.4 97.1 0.5 0.7055 0.9999 1975793 ChemDiv1_011779 COc1ccc(/C=C\2/S/C(=N/c3ccc(Cl)c(c3)C(=O)O)/NC2=O)cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H10 compound treatment 283.5 96.1 0.5 278.2 94.9 0.49 0.7033 1.0 1782659 ChemDiv1_011780 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccccc4[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H11 compound treatment 279.7 92.3 0.48 278.9 95.6 0.5 0.6919 0.9999 1947516 ChemDiv1_011781 COc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H12 compound treatment 280.8 93.4 0.49 274.8 91.5 0.48 0.6809 0.9999 1975794 ChemDiv1_011782 CC/1=NN(C(=O)\C1=C/Nc2ccc3nc(C)[nH]c3c2)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H13 compound treatment 284.5 97.1 0.51 281.9 98.6 0.51 0.7206 1.0 1975795 ChemDiv1_011783 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OC)c(CSc3ccccn3)c2)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H14 compound treatment 284.8 97.4 0.51 277.2 93.9 0.49 0.7045 0.9998 1175806 ChemDiv1_011784 Clc1ccc(Nc2nc3nonc3nc2N4CCCCC4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H15 compound treatment 291.4 104.0 0.54 282.2 98.9 0.51 0.7472 0.9996 1975796 ChemDiv1_011785 CC(NC(=O)CSc1nc(C)cc(c1C#N)C(F)(F)F)C2(CC3CC4CC(C3)C2)C4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H16 compound treatment 282.8 95.4 0.5 279.0 95.7 0.5 0.7037 1.0 1315263 ChemDiv1_011786 Cn1cnnc1SCC(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc45)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H17 compound treatment 280.8 93.4 0.49 282.3 99.0 0.51 0.7084 0.9996 1234681 ChemDiv1_011787 O=C(CSc1nc2ccccc2[nH]1)Nc3nc4c(ccc5ccccc45)s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H18 compound treatment 284.2 96.8 0.5 276.5 93.2 0.48 0.6997 0.9998 1247852 ChemDiv1_011788 Cc1cc(C)c2nc3sc(=Cc4cccc(OCc5ccc(Cl)cc5)c4)c(=O)n3c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H19 compound treatment 280.4 93.0 0.48 275.6 92.3 0.48 0.6823 1.0 1975797 ChemDiv1_011789 Brc1ccccc1CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H20 compound treatment 280.0 92.6 0.48 277.7 94.4 0.49 0.6886 1.0 1364996 ChemDiv1_011790 CCCc1n[nH]c2OC(=C(C(=O)OCC)C3(C(=O)Nc4ccc(Br)cc43)c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H21 compound treatment 286.9 99.5 0.52 283.6 100.0 0.52 0.7357 1.0 1402170 ChemDiv1_011791 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5cccc(OC)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H22 compound treatment 276.7 89.3 0.47 277.6 94.3 0.49 0.6761 0.9997 1584788 ChemDiv1_011792 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H23 mock treatment 280.4 93.0 0.48 273.3 90.0 0.47 0.6739 0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 H24 mock treatment 77.2 -110.0 -0.58 76.6 -107.0 -0.55 -0.7986 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I01 compound treatment 285.1 97.7 0.51 277.1 93.8 0.49 0.7052 0.9998 1975798 ChemDiv1_011793 Brc1ccccc1C(=O)N2CCN(CC2)C3=NS(=O)(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I02 compound treatment 283.7 96.3 0.5 278.7 95.4 0.5 0.7059 1.0 1975799 ChemDiv1_011794 OC1(CC(=NN1C(=O)c2ccccn2)C(F)(F)F)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I03 compound treatment 285.5 98.1 0.51 281.2 97.9 0.51 0.7217 1.0 1222523 ChemDiv1_011795 Fc1cccc(Cl)c1COc2ccc(Cl)cc2C=c3sc4nc5ccccc5n4c3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I04 compound treatment 284.9 97.5 0.51 282.3 99.0 0.51 0.7236 1.0 1192349 ChemDiv1_011796 Fc1ccc(cc1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I05 compound treatment 285.6 98.2 0.51 277.7 94.4 0.49 0.7092 0.9998 1975800 ChemDiv1_011797 Cc1ccc(cc1C)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5Cl)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I06 compound treatment 284.7 97.3 0.51 280.9 97.6 0.51 0.7177 1.0 1975801 ChemDiv1_011798 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I07 compound treatment 395.9 208.0 1.09 384.6 201.0 1.05 1.509 0.9998 1666423 ChemDiv1_011799 Cc1ccc2c(nc3sc(=Cc4ccc(o4)c5ccccc5C(=O)O)c(=O)n32)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I08 compound treatment 281.3 93.9 0.49 280.5 97.2 0.51 0.7037 0.9999 1612514 ChemDiv1_011800 CCOC(=O)c1c(CSc2nc(C)c(CC)c(C)c2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I09 compound treatment 286.3 98.9 0.52 284.1 101.0 0.52 0.7354 1.0 1728120 ChemDiv1_011801 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cc6cc(Br)ccc6o5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I10 compound treatment 282.8 95.4 0.5 276.5 93.2 0.48 0.6945 0.9999 1880183 ChemDiv1_011802 [O-][N+](=O)c1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)c(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I11 compound treatment 285.7 98.3 0.51 280.6 97.3 0.51 0.7203 1.0 1259510 ChemDiv1_011803 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(Cl)c4Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I12 compound treatment 285.4 98.0 0.51 278.2 94.9 0.49 0.7103 0.9998 1975802 ChemDiv1_011804 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5cccc(Cl)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I13 compound treatment 283.5 96.1 0.5 278.0 94.7 0.49 0.7026 1.0 1183924 ChemDiv1_011805 CC(C)OC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I14 compound treatment 281.4 94.0 0.49 276.3 93.0 0.48 0.6886 1.0 1975803 ChemDiv1_011806 CCOC(=O)/C=C(\C)/N1N=C(CC1c2ccc(OC)cc2)c3cccc(c3)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I15 compound treatment 282.8 95.4 0.5 280.3 97.0 0.5 0.7085 1.0 1975804 ChemDiv1_011807 Nn1cnn2c(SCC(=O)Nc3nnc(SCC(=O)Nc4ccc(Cl)c(Cl)c4)s3)nnc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I16 compound treatment 284.8 97.4 0.51 276.7 93.4 0.49 0.7026 0.9997 1621849 ChemDiv1_011808 CC(C)c1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I17 compound treatment 285.6 98.2 0.51 275.8 92.5 0.48 0.7023 0.9995 1730354 ChemDiv1_011809 CCOC(=O)c1c(CSc2nc(C)ccc2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I18 compound treatment 280.1 92.7 0.48 276.3 93.0 0.48 0.6838 1.0 1975805 ChemDiv1_011810 FC(F)(F)c1cccc(c1)N2C(=O)CSC23C(=O)N(CN4CCCCC4)c5ccccc53 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I19 compound treatment 280.7 93.3 0.49 281.6 98.3 0.51 0.7055 0.9997 1975806 ChemDiv1_011811 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc3ccccc3[nH]2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I20 compound treatment 278.7 91.3 0.48 276.2 92.9 0.48 0.6783 1.0 1928354 ChemDiv1_011812 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3cccc(c3)[N+](=O)[O-])c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I21 compound treatment 277.9 90.5 0.47 278.9 95.6 0.5 0.6853 0.9997 1201916 ChemDiv1_011813 CCOC(=O)c1sc(NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCCCC3)c(C(=O)OCC)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I22 compound treatment 278.2 90.8 0.47 274.5 91.2 0.47 0.6702 1.0 1273619 ChemDiv1_011814 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I23 mock treatment 279.3 91.9 0.48 276.6 93.3 0.49 0.682 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 I24 mock treatment 77.8 -110.0 -0.57 72.3 -111.0 -0.58 -0.8122 -1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J01 compound treatment 285.8 98.4 0.51 278.3 95.0 0.49 0.7122 0.9998 1245252 ChemDiv1_011815 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC(=O)N)cc4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J02 compound treatment 395.3 208.0 1.08 384.6 201.0 1.05 1.5068 0.9998 1440239 ChemDiv1_011816 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc(Br)c1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J03 compound treatment 295.2 108.0 0.56 287.3 104.0 0.54 0.7799 0.9998 1321872 ChemDiv1_011817 CCN(CC)C(=O)CSc1nc2ccccc2n1C(=O)OCC(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J04 compound treatment 282.5 95.1 0.5 283.1 99.8 0.52 0.7177 0.9997 1975807 ChemDiv1_011818 CC(C)c1ccc(cc1)N2C(=O)CSC23C(=O)N(CN4CCOCC4)c5ccccc53 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J05 compound treatment 285.8 98.4 0.51 279.0 95.7 0.5 0.7148 0.9999 1633909 ChemDiv1_011819 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(OC)cc4OC)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J06 compound treatment 287.2 99.8 0.52 282.4 99.1 0.52 0.7324 1.0 1975808 ChemDiv1_011820 COc1ccc(cc1)c2cc(n3nc(C(=O)NCc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J07 compound treatment 283.2 95.8 0.5 278.2 94.9 0.49 0.7022 1.0 1975809 ChemDiv1_011821 COc1ccc(N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)N)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J08 compound treatment 285.2 97.8 0.51 277.3 94.0 0.49 0.7063 0.9998 1420846 ChemDiv1_011822 Cc1ccc(N2C(=O)CSC23C(=O)Nc4ccccc43)c(C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J09 compound treatment 283.8 96.4 0.5 278.5 95.2 0.5 0.7055 1.0 1493101 ChemDiv1_011823 Cc1ccc(NC(=O)CSc2nc3ccc(NC(=O)CSc4nncn4C)cc3s2)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J10 compound treatment 285.9 98.5 0.51 280.9 97.6 0.51 0.7221 1.0 1975810 ChemDiv1_011824 CCCCC1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J11 compound treatment 287.4 100.0 0.52 280.0 96.7 0.5 0.7243 0.9998 1975811 ChemDiv1_011825 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3F)c4cccs4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J12 compound treatment 285.9 98.5 0.51 275.4 92.1 0.48 0.7019 0.9994 1431326 ChemDiv1_011826 COc1ccc(OC)c(Nc2nc3nonc3nc2Nc4cccc(Cl)c4)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J13 compound treatment 283.1 95.7 0.5 278.8 95.5 0.5 0.7041 1.0 1975812 ChemDiv1_011827 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(F)cc2F)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J14 compound treatment 280.9 93.5 0.49 275.8 92.5 0.48 0.6849 1.0 1716194 ChemDiv1_011828 Cc1ccc(Nc2nc3nonc3nc2Nc4ccccc4F)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J15 compound treatment 284.9 97.5 0.51 282.0 98.7 0.51 0.7225 1.0 1975813 ChemDiv1_011829 COC(=O)c1ccccc1NC(=O)CSc2nnc(SCC(=O)Nc3ccccc3C(=O)OC)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J16 compound treatment 282.2 94.8 0.49 276.1 92.8 0.48 0.6908 0.9999 1275700 ChemDiv1_011830 CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(C)c3cc(Br)c(OC)cc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J17 compound treatment 282.8 95.4 0.5 274.1 90.8 0.47 0.6857 0.9997 1510750 ChemDiv1_011831 Fc1ccccc1Nc2nc3nonc3nc2N4CCCCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J18 compound treatment 283.4 96.0 0.5 273.3 90.0 0.47 0.685 0.9994 1409948 ChemDiv1_011832 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCC(=O)Nc5ccc(C)c(C)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J19 compound treatment 288.7 101.0 0.53 282.7 99.4 0.52 0.7391 0.9999 1575848 ChemDiv1_011833 CC(CCc1ccccc1)Nc2nc(Cl)nc(NCCN3CCOCC3)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J20 compound treatment 280.6 93.2 0.49 276.4 93.1 0.48 0.686 1.0 1975814 ChemDiv1_011834 Cc1c(NC(=O)CSc2nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3s2)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J21 compound treatment 278.7 91.3 0.48 272.6 89.3 0.46 0.6651 0.9999 1975815 ChemDiv1_011835 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccc(cc43)[N+](=O)[O-])c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J22 compound treatment 280.5 93.1 0.49 277.1 93.8 0.49 0.6882 1.0 1210871 ChemDiv1_011836 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)N(CCc4ccccc4)c5ccccc53)c12)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J23 mock treatment 277.6 90.2 0.47 276.5 93.2 0.48 0.6753 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 J24 mock treatment 81.7 -106.0 -0.55 83.3 -100.0 -0.52 -0.7574 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K01 compound treatment 289.5 102.0 0.53 279.5 96.2 0.5 0.7302 0.9995 1975816 ChemDiv1_011837 CCCCOc1ccc(cc1)C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K02 compound treatment 284.0 96.6 0.5 278.9 95.6 0.5 0.7078 1.0 1975817 ChemDiv1_011838 Cc1nnc(NC(=O)COC(=O)CSc2nc(cc(n2)c3ccccc3)c4ccccc4)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K03 compound treatment 286.8 99.4 0.52 279.2 95.9 0.5 0.7192 0.9998 1942760 ChemDiv1_011839 C/N=C\1/S/C(=C\c2cc3OCOc3cc2Br)/C(=O)N1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K04 compound treatment 284.6 97.2 0.51 282.1 98.8 0.51 0.7217 1.0 1143177 ChemDiv1_011840 Clc1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K05 compound treatment 283.9 96.5 0.5 280.5 97.2 0.51 0.7133 1.0 1336178 ChemDiv1_011841 O=C1N(CN2CCN(CC2)c3ccccc3)c4ccccc4C51OCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K06 compound treatment 286.5 99.1 0.52 282.4 99.1 0.52 0.7298 1.0 1975818 ChemDiv1_011842 OC1(CC(=NN1C(=O)c2ccccc2[N+](=O)[O-])C(F)(F)F)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K07 compound treatment 282.1 94.7 0.49 279.8 96.5 0.5 0.7041 1.0 1473372 ChemDiv1_011843 COc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K08 compound treatment 281.5 94.1 0.49 278.3 95.0 0.49 0.6963 1.0 1975819 ChemDiv1_011844 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc(SCC(=O)O)c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K09 compound treatment 286.7 99.3 0.52 275.7 92.4 0.48 0.706 0.9993 1442381 ChemDiv1_011845 Cc1nnc(SCC(=O)Nc2ccc3nc(SCC(=O)NC4CCCCC4)sc3c2)s1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K10 compound treatment 283.3 95.9 0.5 279.0 95.7 0.5 0.7055 1.0 1975820 ChemDiv1_011846 [O-][N+](=O)c1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccc(Br)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K11 compound treatment 284.9 97.5 0.51 277.5 94.2 0.49 0.7059 0.9998 1211362 ChemDiv1_011847 CCOc1ccc2nc(SCC(=O)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K12 compound treatment 287.2 99.8 0.52 279.5 96.2 0.5 0.7218 0.9998 1975821 ChemDiv1_011848 Cc1ccc(/C=C/2\SC(=S)N(CN3CCCCCC3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K13 compound treatment 286.3 98.9 0.52 276.2 92.9 0.48 0.7063 0.9995 1736383 ChemDiv1_011849 CCOc1cc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(Br)cc1O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K14 compound treatment 283.3 95.9 0.5 282.0 98.7 0.51 0.7166 0.9999 1566463 ChemDiv1_011850 O=C(Cc1cccc2ccccc12)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K15 compound treatment 281.4 94.0 0.49 282.5 99.2 0.52 0.7114 0.9997 1432216 ChemDiv1_011851 Clc1ccc(OCc2nnc(NC(=O)c3cc(ccc3Cl)S(=O)(=O)N4CCOCC4)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K16 compound treatment 283.1 95.7 0.5 278.5 95.2 0.5 0.703 1.0 1302573 ChemDiv1_011852 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)OCc4ccccc4)c(N)c23 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K17 compound treatment 285.2 97.8 0.51 279.1 95.8 0.5 0.7129 0.9999 1289812 ChemDiv1_011853 Cc1ccc(SCC(=O)Nc2nnc(CCS(=O)(=O)c3ccc(C)cc3)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K18 compound treatment 282.5 95.1 0.5 276.2 92.9 0.48 0.6923 0.9999 1664153 ChemDiv1_011854 CC1(C)CC(=O)C2=C(C1)OC3=C(C(=O)CC(C)(C)C3)C42C(=O)Nc5ccccc54 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K19 compound treatment 282.0 94.6 0.49 274.0 90.7 0.47 0.6824 0.9997 1568883 ChemDiv1_011855 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K20 compound treatment 280.3 92.9 0.48 274.9 91.6 0.48 0.6794 1.0 1385329 ChemDiv1_011856 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K21 compound treatment 281.7 94.3 0.49 275.6 92.3 0.48 0.6871 0.9999 1975822 ChemDiv1_011857 Cc1ccc(cc1NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)Nc3cccc(c3)C(=O)O)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K22 compound treatment 282.8 95.4 0.5 274.8 91.5 0.48 0.6883 0.9998 1603282 ChemDiv1_011858 COc1ccc(OC)c(c1)N2C(=C(C#N)C(C3=C2CCCC3=O)c4ccc(OC)c(O)c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K23 mock treatment 283.3 95.9 0.5 275.0 91.7 0.48 0.6908 0.9997 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 K24 mock treatment 78.2 -109.0 -0.57 76.7 -107.0 -0.55 -0.7946 -0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L01 compound treatment 286.3 98.9 0.52 282.5 99.2 0.52 0.7295 1.0 1566192 ChemDiv1_011859 COc1ccc(N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(F)cc4)N)c(OC)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L02 compound treatment 287.3 99.9 0.52 281.5 98.2 0.51 0.7295 0.9999 1975823 ChemDiv1_011860 CN1C(=O)C(=c2sc3=NC4(N(C)C(=O)N(C)C4(Nn3c2=O)c5ccccc5)c6ccccc6)c7ccccc17 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L03 compound treatment 283.4 96.0 0.5 277.5 94.2 0.49 0.7004 0.9999 1140976 ChemDiv1_011861 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cc(OC)ccc2OC)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L04 compound treatment 284.9 97.5 0.51 276.8 93.5 0.49 0.7034 0.9998 1975824 ChemDiv1_011862 FC(F)(F)c1cccc(c1)N2C(=O)c3ccccc3NC24C(=O)N(Cc5c(Cl)cccc5Cl)c6ccccc64 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L05 compound treatment 284.0 96.6 0.5 280.7 97.4 0.51 0.7144 1.0 1462456 ChemDiv1_011863 COC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)CSc4nnc(C)s4)cc3s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L06 compound treatment 288.8 101.0 0.53 282.8 99.5 0.52 0.7398 0.9999 1975825 ChemDiv1_011864 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C/Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)/C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L07 compound treatment 281.5 94.1 0.49 276.1 92.8 0.48 0.6882 1.0 1455897 ChemDiv1_011865 CC1CC(N(C(=O)c2cccc(F)c2)c3ccccc3)c4ccccc4N1C(=O)c5cccc(F)c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L08 compound treatment 282.0 94.6 0.49 274.8 91.5 0.48 0.6853 0.9998 1782210 ChemDiv1_011866 CC1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)c3ccc(Cl)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L09 compound treatment 282.2 94.8 0.49 278.3 95.0 0.49 0.6989 1.0 1975826 ChemDiv1_011867 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L10 compound treatment 301.9 114.0 0.6 294.3 111.0 0.58 0.8304 0.9999 1270349 ChemDiv1_011868 COC(=O)c1ccc(cc1)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L11 compound treatment 281.0 93.6 0.49 279.4 96.1 0.5 0.6985 0.9999 1975827 ChemDiv1_011869 CN(C)N/1C(=O)/C(=C\c2cc3OCOc3cc2[N+](=O)[O-])/S\C1=N/c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L12 compound treatment 283.9 96.5 0.5 280.6 97.3 0.51 0.7136 1.0 1365100 ChemDiv1_011870 Cn1ccnc1SCC(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(F)cc4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L13 compound treatment 280.2 92.8 0.48 275.2 91.9 0.48 0.6801 1.0 1694028 ChemDiv1_011871 COc1ccc(cc1OCc2ccccc2)C3C(=C(N)Oc4cc(C)oc(=O)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L14 compound treatment 282.7 95.3 0.5 274.7 91.4 0.48 0.6875 0.9998 1432148 ChemDiv1_011872 S=c1sc2c(ncnc2n1c3ccccc3)N4CCCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L15 compound treatment 281.6 94.2 0.49 278.6 95.3 0.5 0.6978 1.0 1975828 ChemDiv1_011873 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2nc3ccccc3s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L16 compound treatment 282.0 94.6 0.49 280.8 97.5 0.51 0.7074 0.9999 1975829 ChemDiv1_011874 Nc1ccc2[nH]c(SCc3nc4ccccc4c(=O)n3c5cccc(c5)C(F)(F)F)nc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L17 compound treatment 285.9 98.5 0.51 277.8 94.5 0.49 0.7107 0.9998 1261618 ChemDiv1_011875 Cc1cc2nc3sc(=Cc4cc(Cl)ccc4OCc5ccccc5)c(=O)n3c2cc1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L18 compound treatment 284.9 97.5 0.51 276.0 92.7 0.48 0.7004 0.9996 1975830 ChemDiv1_011876 FC(F)(F)c1cccc(c1)N2C(=O)CSC23C(=O)N(CN4CCN(CC4)c5ccccc5)c6ccccc63 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L19 compound treatment 280.4 93.0 0.48 277.0 93.7 0.49 0.6875 1.0 1611824 ChemDiv1_011877 Fc1ccccc1CN2C(=O)C3(Nc4ccccc4C(=O)N3c5ccccc5)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L20 compound treatment 283.1 95.7 0.5 277.4 94.1 0.49 0.6989 1.0 1723595 ChemDiv1_011878 COc1ccc(cc1)c2csc(NC(=O)c3cc4cc(Br)ccc4oc3=O)n2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L21 compound treatment 281.2 93.8 0.49 272.8 89.5 0.47 0.675 0.9997 1929226 ChemDiv1_011879 C=CCc1cccc2cc(C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34)c(=O)oc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L22 compound treatment 286.1 98.7 0.51 277.7 94.4 0.49 0.7111 0.9997 1652351 ChemDiv1_011880 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3cc(Cl)cc(Cl)c3OC(=O)N4CCOCC4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L23 mock treatment 279.7 92.3 0.48 273.6 90.3 0.47 0.6724 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 L24 mock treatment 77.2 -110.0 -0.58 78.4 -105.0 -0.55 -0.792 -0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M01 compound treatment 300.7 113.0 0.59 301.1 118.0 0.61 0.851 0.9998 1975831 ChemDiv1_011881 COc1ccc(/C=C\2/SC(=S)N(CN3CCCCC3C)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M02 compound treatment 285.4 98.0 0.51 279.3 96.0 0.5 0.7144 0.9999 1467697 ChemDiv1_011882 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M03 compound treatment 287.2 99.8 0.52 278.6 95.3 0.5 0.7185 0.9997 1477109 ChemDiv1_011883 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OCc5ccc(Cl)c(Cl)c5)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M04 compound treatment 284.1 96.7 0.5 274.8 91.5 0.48 0.6931 0.9996 1975832 ChemDiv1_011884 COc1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(cc5)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M05 compound treatment 286.9 99.5 0.52 283.0 99.7 0.52 0.7335 1.0 1975833 ChemDiv1_011885 Clc1ccc(Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26)cc1Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M06 compound treatment 285.4 98.0 0.51 282.9 99.6 0.52 0.7276 1.0 1135740 ChemDiv1_011886 COc1ccc(OC)c(c1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M07 compound treatment 282.7 95.3 0.5 280.2 96.9 0.5 0.7077 1.0 1975834 ChemDiv1_011887 Cc1c(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(=O)n(C)n1c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M08 compound treatment 418.3 231.0 1.2 418.2 235.0 1.22 1.7152 1.0 1975835 ChemDiv1_011888 CN(C)c1ccc(/C=C\2/SC(=S)N(CN3CCCC3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M09 compound treatment 279.9 92.5 0.48 277.9 94.6 0.49 0.689 1.0 1975836 ChemDiv1_011889 O=C(CSc1nc2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2s1)NC5CC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M10 compound treatment 285.4 98.0 0.51 275.9 92.6 0.48 0.7019 0.9996 1975837 ChemDiv1_011890 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccccc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M11 compound treatment 283.0 95.6 0.5 279.2 95.9 0.5 0.7052 1.0 1452689 ChemDiv1_011891 O=C1N(CN2CCC(Cc3ccccc3)CC2)c4ccccc4C51OCCO5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M12 compound treatment 285.2 97.8 0.51 279.3 96.0 0.5 0.7137 0.9999 1975838 ChemDiv1_011892 CC(C)c1ccc(/C=C\2/SC(=S)N(CN3CCCC3)C2=O)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M13 compound treatment 284.2 96.8 0.5 278.3 95.0 0.49 0.7063 0.9999 1975839 ChemDiv1_011893 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4cccc(Br)c4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M14 compound treatment 279.9 92.5 0.48 273.2 89.9 0.47 0.6717 0.9999 1975840 ChemDiv1_011894 COc1ccc(cc1CSc2nc3ccc(NC(=O)C)cc3s2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M15 compound treatment 278.1 90.7 0.47 280.1 96.8 0.5 0.6904 0.9995 1975841 ChemDiv1_011895 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(O)cc4)C(=O)OCCOc5ccccc5)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M16 compound treatment 278.9 91.5 0.48 280.6 97.3 0.51 0.6952 0.9996 1975842 ChemDiv1_011896 ClC1=CCC2C(C1)C(=O)N(CN(CN3C(=O)C4CC=C(Cl)CC4C3=O)C5CCCCC5)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M17 compound treatment 282.8 95.4 0.5 277.2 93.9 0.49 0.6971 1.0 1163691 ChemDiv1_011897 Clc1ccc(C2Nc3ccccc3C(=O)N2c4ccc(I)cc4)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M18 compound treatment 280.1 92.7 0.48 277.4 94.1 0.49 0.6879 1.0 1975843 ChemDiv1_011898 CCOCCn1c2ccccc2c3nc4ccccc4nc13 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M19 compound treatment 277.0 89.6 0.47 278.4 95.1 0.49 0.6801 0.9996 1975844 ChemDiv1_011899 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M20 compound treatment 278.9 91.5 0.48 273.7 90.4 0.47 0.6698 1.0 1975845 ChemDiv1_011900 Cc1ccc(SCC(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Br)cc3)s2)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M21 compound treatment 277.7 90.3 0.47 274.4 91.1 0.47 0.668 1.0 1975846 ChemDiv1_011901 Cc1cccc2oc3cc(NC4CCCCC4)c5c(=O)c6ccccc6c(=O)c5c3[nH]c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M22 compound treatment 279.4 92.0 0.48 271.6 88.3 0.46 0.664 0.9998 1494647 ChemDiv1_011902 Cc1c(N2C(=O)CSC23C(=O)Nc4ccccc43)c(=O)n(c5ccccc5)n1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M23 mock treatment 284.3 96.9 0.51 272.6 89.3 0.46 0.6857 0.9991 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 M24 mock treatment 183.2 -4.23 -0.02 182.4 -0.859 0.0 -0.0188 -0.8334 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N01 compound treatment 288.3 101.0 0.53 279.4 96.1 0.5 0.7255 0.9997 1522013 ChemDiv1_011903 COc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N02 compound treatment 282.6 95.2 0.5 281.9 98.6 0.51 0.7136 0.9999 1697773 ChemDiv1_011904 COc1nc(NCC=C)nc(n1)N2CCC(Cc3ccccc3)CC2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N03 compound treatment 284.3 96.9 0.51 278.4 95.1 0.49 0.707 0.9999 1975847 ChemDiv1_011905 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3F)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N04 compound treatment 286.1 98.7 0.51 280.1 96.8 0.5 0.7199 0.9999 1975848 ChemDiv1_011906 CCOC(=O)c1ccc2nc(NC(=O)COC(=O)CCC(=O)Nc3ccccc3C(=O)OC)sc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N05 compound treatment 284.3 96.9 0.51 275.1 91.8 0.48 0.6949 0.9996 1197210 ChemDiv1_011907 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCC(=O)Nc4ccccc4)sc3c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N06 compound treatment 285.2 97.8 0.51 277.3 94.0 0.49 0.7063 0.9998 1975849 ChemDiv1_011908 CN(C)C(=O)c1ccc(N/C=C\2/C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N07 compound treatment 278.8 91.4 0.48 276.6 93.3 0.49 0.6801 1.0 1975850 ChemDiv1_011909 CC1=CC(C)(C)Nc2ccc(OC(=O)CN3C(=O)C4CCCCC4C3=O)cc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N08 compound treatment 284.5 97.1 0.51 280.8 97.5 0.51 0.7166 1.0 1975851 ChemDiv1_011910 OC(=O)c1ccc(cc1)N2C(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/SC2=S 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N09 compound treatment 281.9 94.5 0.49 275.9 92.6 0.48 0.689 0.9999 1975852 ChemDiv1_011911 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(cc3)S(=O)(=O)N)c4ccc(cc4)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N10 compound treatment 283.2 95.8 0.5 277.9 94.6 0.49 0.7011 1.0 1975853 ChemDiv1_011912 CCCCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccncc3)C2=O)/c4ccccc14 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N11 compound treatment 280.7 93.3 0.49 277.1 93.8 0.49 0.689 1.0 1975854 ChemDiv1_011913 O=C(CN1CCCCC1)Nc2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)s2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N12 compound treatment 346.1 159.0 0.83 352.8 170.0 0.88 1.2084 0.9995 1975855 ChemDiv1_011914 COc1cc(/C=C\2/S/C(=N/C)/N(C)C2=O)cc(Br)c1OC(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N13 compound treatment 292.4 105.0 0.55 288.3 105.0 0.55 0.7733 1.0 1136864 ChemDiv1_011915 Cc1ccc2c(nc3sc(=Cc4cc(c(O)c(c4)C(C)(C)C)C(C)(C)C)c(=O)n32)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N14 compound treatment 282.6 95.2 0.5 275.5 92.2 0.48 0.6901 0.9998 1975856 ChemDiv1_011916 O=C1C2C(C3C2C4C=CC3C5C4C(=O)N(Cc6ccco6)C5=O)C(=O)N1Cc7ccco7 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N15 compound treatment 279.9 92.5 0.48 273.4 90.1 0.47 0.6724 0.9999 1975857 ChemDiv1_011917 Cc1nc(SC2CC(=O)N(C2=O)c3ccccc3)c(C#N)c(C)c1C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N16 compound treatment 282.9 95.5 0.5 276.8 93.5 0.49 0.696 0.9999 1168851 ChemDiv1_011918 Fc1ccccc1Nc2nc3nonc3nc2Nc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N17 compound treatment 282.6 95.2 0.5 278.0 94.7 0.49 0.6993 1.0 1452497 ChemDiv1_011919 Clc1ccc(OCc2ccccc2Cl)c(C=c3sc4nc5ccccc5n4c3=O)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N18 compound treatment 281.1 93.7 0.49 277.8 94.5 0.49 0.693 1.0 1975858 ChemDiv1_011920 Cc1ccc(cc1)C(=O)OCCN(Cc2ccccc2)C3=NS(=O)(=O)c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N19 compound treatment 279.3 91.9 0.48 273.3 90.0 0.47 0.6698 0.9999 1716768 ChemDiv1_011921 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCc4cccnc4)c2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N20 compound treatment 282.7 95.3 0.5 275.9 92.6 0.48 0.6919 0.9999 1975859 ChemDiv1_011922 NN1C=NN2C1NN=C2SCC(=O)Nc3nnc(SCC(=O)Nc4ccc(Cl)c(Cl)c4)s3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N21 compound treatment 277.3 89.9 0.47 270.9 87.6 0.46 0.6536 0.9999 1975860 ChemDiv1_011923 COc1cccc2cc(C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34)c(=O)oc12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N22 compound treatment 278.8 91.4 0.48 273.1 89.8 0.47 0.6673 0.9999 1975861 ChemDiv1_011924 COc1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccccn4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N23 mock treatment 278.2 90.8 0.47 276.4 93.1 0.48 0.6772 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 N24 mock treatment 189.0 1.57 0.01 184.8 1.54 0.01 0.0115 0.9999 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O01 compound treatment 285.0 97.6 0.51 279.3 96.0 0.5 0.7129 1.0 1975862 ChemDiv1_011925 CCN(CC)Cc1cc(NC2=NS(=O)(=O)c3ccccc23)ccc1OC(=O)c4ccc(OC)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O02 compound treatment 285.5 98.1 0.51 278.3 95.0 0.49 0.7111 0.9998 1171366 ChemDiv1_011926 COc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(OC)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O03 compound treatment 286.7 99.3 0.52 278.5 95.2 0.5 0.7162 0.9997 1975863 ChemDiv1_011927 CC/1=NN(C(=O)\C1=C\c2cc3OCOc3cc2Br)c4ccc(Cl)c(c4)C(=O)O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O04 compound treatment 281.9 94.5 0.49 281.2 97.9 0.51 0.7085 0.9999 1522977 ChemDiv1_011928 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccco5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O05 compound treatment 282.0 94.6 0.49 275.9 92.6 0.48 0.6894 0.9999 1579129 ChemDiv1_011929 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OCc5c(F)cccc5Cl)c4)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O06 compound treatment 285.0 97.6 0.51 279.1 95.8 0.5 0.7122 0.9999 1152911 ChemDiv1_011930 CCOC(=O)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)C(C)C2=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O07 compound treatment 286.1 98.7 0.51 277.6 94.3 0.49 0.7107 0.9997 1490071 ChemDiv1_011931 CC1=C(C(C(=C(N)O1)C#N)c2cccc(F)c2)C(=O)OC(C)(C)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O08 compound treatment 286.5 99.1 0.52 275.8 92.5 0.48 0.7056 0.9994 1975864 ChemDiv1_011932 CC1CCN(CN2C(=O)/C(=C\c3ccc(C)cc3)/SC2=S)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O09 compound treatment 281.2 93.8 0.49 278.2 94.9 0.49 0.6949 1.0 1686424 ChemDiv1_011933 Nc1c(oc2ccc(Cl)cc12)C(=O)c3ccc(F)cc3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O10 compound treatment 284.7 97.3 0.51 276.4 93.1 0.48 0.7011 0.9997 1975865 ChemDiv1_011934 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(Cl)cc5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O11 compound treatment 282.2 94.8 0.49 278.4 95.1 0.49 0.6993 1.0 1404914 ChemDiv1_011935 O=C(CSCC(=O)Nc1ccc2ccccc2c1)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O12 compound treatment 281.9 94.5 0.49 277.7 94.4 0.49 0.6956 1.0 1584114 ChemDiv1_011936 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Br)c1OCC#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O13 compound treatment 276.7 89.3 0.47 277.5 94.2 0.49 0.6757 0.9997 1975866 ChemDiv1_011937 CC1CCN(CC1)c2ccc(cc2[N+](=O)[O-])c3c(C#N)c(N)n4c5ccccc5nc4c3C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O14 compound treatment 311.9 124.0 0.65 286.9 104.0 0.54 0.8401 0.9957 1975867 ChemDiv1_011938 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3cccc(Cl)c3C)\S1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O15 compound treatment 278.1 90.7 0.47 278.7 95.4 0.5 0.6853 0.9997 1975868 ChemDiv1_011939 NC1=C(C#N)C(C(=C(O1)C2CC2)n3cnc(n3)[N+](=O)[O-])c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O16 compound treatment 280.9 93.5 0.49 275.0 91.7 0.48 0.682 0.9999 1178324 ChemDiv1_011940 Clc1ccc(cc1Cl)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O17 compound treatment 278.2 90.8 0.47 276.5 93.2 0.48 0.6775 0.9999 1975869 ChemDiv1_011941 O=C(Nc1nnc(CCCCc2nnc(NC(=O)c3ccco3)s2)s1)c4ccco4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O18 compound treatment 277.9 90.5 0.47 278.7 95.4 0.5 0.6845 0.9997 1780811 ChemDiv1_011942 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cc(cc(c4)[N+](=O)[O-])[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O19 compound treatment 274.5 87.1 0.45 272.2 88.9 0.46 0.6481 1.0 1975870 ChemDiv1_011943 Nc1cccc(c1)C(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O20 compound treatment 283.8 96.4 0.5 280.3 97.0 0.5 0.7122 1.0 1943353 ChemDiv1_011944 COc1ccc(cc1N2C(=O)C3C4C=CC(C3C2=O)C4=C(c5ccccc5)c6ccccc6)C(=O)C 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O21 compound treatment 280.4 93.0 0.48 276.4 93.1 0.48 0.6853 1.0 1975871 ChemDiv1_011945 Clc1ccc2[nH]c3c(cc(N4CCOCC4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O22 compound treatment 274.7 87.3 0.46 268.4 85.1 0.44 0.6349 0.9999 1624510 ChemDiv1_011946 Nc1c(oc2ccc(Cl)cc12)C(=O)C3CC3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O23 mock treatment 279.7 92.3 0.48 274.4 91.1 0.47 0.6754 1.0 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 O24 mock treatment 94.8 -92.6 -0.48 94.0 -89.3 -0.46 -0.6698 -0.9998 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P01 compound treatment 289.5 102.0 0.53 279.4 96.1 0.5 0.7299 0.9995 1975872 ChemDiv1_011947 COc1ccc(cc1c2ccc(C=c3sc4nc5c(C)cc(C)cc5n4c3=O)o2)[N+](=O)[O-] 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P02 compound treatment 286.5 99.1 0.52 276.1 92.8 0.48 0.7067 0.9994 1725336 ChemDiv1_011948 CCOC(=O)C1CCN(CN2C(=O)C3(SCC(=O)N3c4ccc(C)cc4)c5ccccc25)CC1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P03 compound treatment 289.0 102.0 0.53 277.9 94.6 0.49 0.7225 0.9993 1975873 ChemDiv1_011949 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3F)c4ccsc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P04 compound treatment 285.2 97.8 0.51 279.9 96.6 0.5 0.7159 1.0 1975874 ChemDiv1_011950 Clc1ccc(OCCCC(=O)NC2=NN(C(=O)C2)c3ccccc3)c(Cl)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P05 compound treatment 273.2 85.8 0.45 273.3 90.0 0.47 0.6473 0.9997 1975875 ChemDiv1_011951 Cc1ccc(cc1)C2=NNC3(S2)C(=O)Nc4ccc(C)cc43 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P06 compound treatment 286.2 98.8 0.52 278.8 95.5 0.5 0.7155 0.9998 1975876 ChemDiv1_011952 CC(=O)Nc1cccc(N/C=C\2/C(=NN(C2=O)c3ccc(F)cc3)C)c1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P07 compound treatment 285.8 98.4 0.51 277.7 94.4 0.49 0.71 0.9998 1975877 ChemDiv1_011953 CCN(CC)C(=O)Oc1cccc2C(=O)c3c(OC(=O)N(CC)CC)cccc3C(=O)c12 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P08 compound treatment 279.8 92.4 0.48 276.7 93.4 0.49 0.6842 1.0 1639779 ChemDiv1_011954 CC(C)Cc1cc(c(C#N)c(NC(=O)C)n1)c2cccc(Br)c2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P09 compound treatment 281.4 94.0 0.49 274.3 91.0 0.47 0.6813 0.9998 1713834 ChemDiv1_011955 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(F)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P10 compound treatment 283.5 96.1 0.5 275.7 92.4 0.48 0.6942 0.9998 1975878 ChemDiv1_011956 CC/1=NN(C(=O)\C1=C/Nc2cccc(Cl)c2Cl)c3c(Cl)cc(Cl)cc3Cl 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P11 compound treatment 283.5 96.1 0.5 278.1 94.8 0.49 0.703 1.0 1975879 ChemDiv1_011957 [O-][N+](=O)c1cc(C#N)ccc1Oc2ccc(cc2)N3C(=O)C4CCCCC4C3=O 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P12 compound treatment 284.2 96.8 0.5 281.3 98.0 0.51 0.7173 1.0 1975880 ChemDiv1_011958 Cc1ccc(cc1)C(=O)OC(CNC2=NS(=O)(=O)c3ccccc23)COc4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P13 compound treatment 283.4 96.0 0.5 274.1 90.8 0.47 0.6879 0.9996 1975881 ChemDiv1_011959 Cc1cc(cc([N+](=O)[O-])c1C)c2ccc(C=c3sc4nc5cc(C)c(C)cc5n4c3=O)o2 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P14 compound treatment 280.8 93.4 0.49 276.6 93.3 0.49 0.6875 1.0 1975882 ChemDiv1_011960 CC(CN1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(C)cc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P15 compound treatment 280.0 92.6 0.48 275.8 92.5 0.48 0.6816 1.0 1567665 ChemDiv1_011961 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4cc(OC)c(OC)cc4OC)C(=O)CCC3)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P16 compound treatment 283.6 96.2 0.5 277.9 94.6 0.49 0.7026 1.0 1729978 ChemDiv1_011962 Clc1ccc(Nc2nc3nonc3nc2NCCc4ccccc4)cc1 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P17 compound treatment 282.7 95.3 0.5 280.4 97.1 0.5 0.7085 1.0 1314485 ChemDiv1_011963 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccccc5F)C(=O)CC(C)(C)C3 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P18 compound treatment 282.6 95.2 0.5 276.1 92.8 0.48 0.6923 0.9999 1975883 ChemDiv1_011964 CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCOc3ccccc3c4ccccc4 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P19 compound treatment 284.7 97.3 0.51 275.9 92.6 0.48 0.6993 0.9997 1975884 ChemDiv1_011965 Fc1ccccc1CN2C(=O)C3(Nc4sc5CCCCc5c4C(=O)N3CCc6ccccc6)c7ccccc27 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P20 compound treatment 280.3 92.9 0.48 277.0 93.7 0.49 0.6871 1.0 1975885 ChemDiv1_011966 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P21 compound treatment 281.6 94.2 0.49 274.9 91.6 0.48 0.6842 0.9999 1975886 ChemDiv1_011967 Fc1cccc(Cl)c1Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P22 compound treatment 281.4 94.0 0.49 276.0 92.7 0.48 0.6875 1.0 1395601 ChemDiv1_011968 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4ccccc4OC(=O)N5CCOCC5 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P23 mock treatment 285.4 98.0 0.51 276.2 92.9 0.48 0.703 0.9996 299.0521 raw{Pol(mP)}(299.0521) CMVPolymeraseBindingAssay 299.0521.620 P24 mock treatment 95.1 -92.3 -0.48 85.3 -98.0 -0.51 -0.7006 -0.9996