ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A01 compound treatment 125.0 -70.2 -0.69 68.0 -84.7 -1.06 67.5 -70.053459119497 -0.997104520316568 -1.5837 -0.9851 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A02 mock treatment 177.0 -18.2 -0.18 104.0 -48.7 -0.61 116.0 -21.553459119497 -0.306780732695147 -0.6307 -0.8971 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A03 mock treatment 155.0 -40.2 -0.4 121.5 -31.2 -0.39 132.0 -5.55345911949701 -0.0790450501808638 -0.4984 -0.8898 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A04 mock treatment 195.0 -0.173 0.0 129.0 -23.7 -0.3 134.0 -3.55345911949701 -0.0505780898665784 -0.2008 -0.6698 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A05 mock treatment 133.5 -61.7 -0.61 85.0 -67.7 -0.84 136.5 -1.05345911949701 -0.0149943894737217 -0.8461 -0.8141 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A06 mock treatment 178.5 -16.7 -0.16 114.0 -38.7 -0.48 180.0 42.446540880503 0.604161997361986 -0.0244 -0.0308 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A07 mock treatment 201.5 6.33 0.06 164.0 11.3 0.14 131.0 -6.55345911949701 -0.0932785303380065 0.0632 0.3516 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A08 mock treatment 199.5 4.33 0.04 153.0 0.278 0.0 159.0 21.446540880503 0.305258914061989 0.2028 0.658 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A09 mock treatment 185.0 -10.2 -0.1 172.0 19.3 0.24 152.0 14.446540880503 0.20562455296199 0.1995 0.6017 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A10 mock treatment 196.0 0.827 0.01 153.0 0.278 0.0 166.0 28.446540880503 0.404893275161988 0.2405 0.5938 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A11 mock treatment 182.0 -13.2 -0.13 154.0 1.28 0.02 125.5 -12.053459119497 -0.171562671202291 -0.1647 -0.7639 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A12 mock treatment 173.0 -22.2 -0.22 170.0 17.3 0.22 148.5 10.946540880503 0.155807372411991 0.0882 0.2565 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A13 mock treatment 180.0 -15.2 -0.15 122.0 -30.7 -0.38 128.0 -9.55345911949701 -0.135978970809435 -0.3856 -0.8913 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A14 mock treatment 210.0 14.8 0.15 131.5 -21.2 -0.26 136.5 -1.05345911949701 -0.0149943894737217 -0.077 -0.2547 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A15 mock treatment 262.0 66.8 0.66 143.5 -9.22 -0.11 122.0 -15.553459119497 -0.221379851752291 0.1856 0.2639 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A16 mock treatment 204.0 8.83 0.09 153.0 0.278 0.0 155.5 17.946540880503 0.25544173351199 0.1996 0.7399 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A17 mock treatment 287.5 92.3 0.91 138.0 -14.7 -0.18 154.0 16.446540880503 0.234091513276276 0.554 0.5794 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A18 mock treatment 201.0 5.83 0.06 158.0 5.28 0.07 158.0 20.446540880503 0.291025433904846 0.2391 0.787 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A19 mock treatment 191.5 -3.67 -0.04 149.0 -3.72 -0.05 166.0 28.446540880503 0.404893275161988 0.1861 0.4549 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A20 mock treatment 199.0 3.83 0.04 144.0 -8.72 -0.11 172.0 34.446540880503 0.490294156104844 0.2421 0.4807 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A21 mock treatment 256.0 60.8 0.6 141.5 -11.2 -0.14 149.0 11.446540880503 0.162924112490562 0.359 0.5645 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A22 mock treatment 269.0 73.8 0.73 156.0 3.28 0.04 144.5 6.94654088050299 0.09887345178342 0.5002 0.681 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A23 compound treatment 122.0 -73.2 -0.72 98.0 -54.7 -0.68 153.0 15.446540880503 0.219858033119133 -0.6824 -0.6719 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 A24 mock treatment 191.0 -4.17 -0.04 172.0 19.3 0.24 233.0 95.446540880503 1.35853644569055 0.8993 0.6515 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B01 mock treatment 164.0 -31.2 -0.31 108.5 -44.2 -0.55 33.5 -104.053459119497 -1.48104284565942 -1.3502 -0.8388 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B02 compound treatment 145.0 -50.2 -0.49 65.5 -87.2 -1.09 109.0 -28.553459119497 -0.406415093795146 -1.147 -0.9098 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B03 compound treatment 148.0 -47.2 -0.46 121.5 -31.2 -0.39 97.0 -40.553459119497 -0.577216855680858 -0.8258 -0.9871 2277 HSCI1_000001 CCc1nc([nH]c1c2ccncc2)c3ccc(OC)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B04 compound treatment 169.0 -26.2 -0.26 112.0 -40.7 -0.51 144.5 6.94654088050299 0.09887345178342 -0.3845 -0.6659 656 HSCI1_000002 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B05 compound treatment 178.0 -17.2 -0.17 114.0 -38.7 -0.48 163.5 25.946540880503 0.369309574769131 -0.1628 -0.2582 2114187 HSCI1_000003 CCOC(=O)c1cccc(NC(=O)CBr)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B06 compound treatment 182.0 -13.2 -0.13 104.0 -48.7 -0.61 101.5 -36.053459119497 -0.513166194973716 -0.7215 -0.896 1362420 HSCI1_000004 Oc1c(I)cc(Cl)cc1C(=O)Nc2cc(ccc2Cl)S(=O)(=O)c3ccc(Cl)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B07 compound treatment 147.5 -47.7 -0.47 156.5 3.78 0.05 136.0 -1.55345911949701 -0.022111129552293 -0.2565 -0.5433 3175973 HSCI1_000005 COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B08 compound treatment 207.5 12.3 0.12 146.0 -6.72 -0.08 169.0 31.446540880503 0.447593715633416 0.2801 0.5945 3175974 HSCI1_000006 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1CCC(O)C(O)C1O)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B09 compound treatment 321.0 126.0 1.24 124.0 -28.7 -0.36 139.0 1.44654088050299 0.0205893109191351 0.5204 0.4036 9 HSCI1_000007 [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B10 compound treatment 451.5 256.0 2.52 299.0 146.0 1.82 230.0 92.446540880503 1.31583600521912 3.2682 0.9673 571 HSCI1_000008 CCCCCCCCCCCCCCCCCCOC[C@H](COC(=O)OC1C(O)C(O)C(O)C(CO)C1O)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B11 mock treatment 114.0 -81.2 -0.8 97.5 -55.2 -0.69 79.0 -58.553459119497 -0.833419498509427 -1.3396 -0.9968 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B12 mock treatment 310.0 115.0 1.13 163.0 10.3 0.13 121.0 -16.553459119497 -0.235613331909434 0.5904 0.5083 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B13 mock treatment 90.0 -105.0 -1.04 74.0 -78.7 -0.98 78.0 -59.553459119497 -0.84765297866657 -1.6532 -0.9966 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B14 mock treatment 187.0 -8.17 -0.08 117.0 -35.7 -0.44 111.0 -26.553459119497 -0.377948133480861 -0.5215 -0.885 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B15 compound treatment 175.5 -19.7 -0.19 167.0 14.3 0.18 156.5 18.946540880503 0.269675213669132 0.1466 0.3892 3055039 HSCI1_000009 Cn1cnc2nc(NCCO)nc(NCc3ccccc3)c12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B16 compound treatment 212.0 16.8 0.17 134.0 -18.7 -0.23 128.0 -9.55345911949701 -0.135978970809435 -0.1175 -0.371 3175975 HSCI1_000010 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1C(O)C(O)C(O)CC1OC)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B17 compound treatment 205.0 9.83 0.1 155.0 2.28 0.03 278.0 140.446540880503 1.99904305276197 1.2264 0.6127 3055043 HSCI1_000011 CCCCCCCCCCCCCCC[C@@H](O)[C@H](N)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B18 compound treatment 341.0 146.0 1.44 157.0 4.28 0.05 235.0 97.446540880503 1.38700340600483 1.6603 0.8315 2326 HSCI1_000012 CCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B19 compound treatment 238.0 42.8 0.42 306.0 153.0 1.91 158.0 20.446540880503 0.291025433904846 1.5136 0.7658 2026 HSCI1_000013 CCCCCCCCCCNc1cc(CO)c2cc[nH]c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B20 compound treatment 150.5 -44.7 -0.44 59.5 -93.2 -1.16 80.0 -57.553459119497 -0.819186018352284 -1.3972 -0.9393 193 HSCI1_000014 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B21 compound treatment 226.5 31.3 0.31 254.0 101.0 1.26 205.0 67.446540880503 0.959999001290554 1.4606 0.9044 3055048 HSCI1_000015 Nc1nc(Cl)nc2n(cnc12)C3OC(CO)[C@H](O)[C@H]3F 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B22 compound treatment 287.5 92.3 0.91 247.5 94.8 1.18 566.0 428.446540880503 6.09828533801907 4.7271 0.753 3175977 HSCI1_000016 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@]41OC(=O)CCCCCCCCC)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B23 mock treatment 175.0 -20.2 -0.2 186.0 33.3 0.41 173.0 35.446540880503 0.504527636261987 0.4159 0.6095 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 B24 compound treatment 136.5 -58.7 -0.58 86.0 -66.7 -0.83 103.5 -34.053459119497 -0.484699234659431 -1.0931 -0.9741 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C01 compound treatment 178.5 -16.7 -0.16 72.0 -80.7 -1.01 84.0 -53.553459119497 -0.762252097723714 -1.1153 -0.8766 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C02 mock treatment 190.0 -5.17 -0.05 122.0 -30.7 -0.38 146.0 8.44654088050299 0.120223672019134 -0.1809 -0.4474 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C03 compound treatment 157.0 -38.2 -0.38 95.0 -57.7 -0.72 165.0 27.446540880503 0.390659795004845 -0.4065 -0.4514 2257 HSCI1_000017 COc1ccc(cc1)C(=O)CBr 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C04 compound treatment 193.5 -1.67 -0.02 101.0 -51.7 -0.64 94.0 -43.553459119497 -0.619917296152287 -0.7393 -0.8268 561 HSCI1_000018 C[C@@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C05 compound treatment 203.5 8.33 0.08 155.0 2.28 0.03 136.5 -1.05345911949701 -0.0149943894737217 0.055 0.6254 2256 HSCI1_000019 Oc1ccc(cc1)C(=O)CBr 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C06 compound treatment 164.5 -30.7 -0.3 76.0 -76.7 -0.96 159.0 21.446540880503 0.305258914061989 -0.5498 -0.5248 1000099 HSCI1_000020 C[C@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C07 compound treatment 192.0 -3.17 -0.03 178.0 25.3 0.31 147.0 9.44654088050299 0.134457152176277 0.2414 0.7021 2258 HSCI1_000021 OC(=O)COc1ccc(cc1)C(=O)CBr 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C08 compound treatment 281.0 85.8 0.84 212.0 59.3 0.74 160.0 22.446540880503 0.319492394219132 1.0985 0.9416 2227 HSCI1_000022 CCCCCCCCCCCCCCCC(=O)C(F)(F)F 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C09 compound treatment 219.0 23.8 0.23 114.5 -38.2 -0.48 165.5 27.946540880503 0.397776535083417 0.0902 0.136 2147 HSCI1_000023 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(=O)(F)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C10 compound treatment 167.5 -27.7 -0.27 97.5 -55.2 -0.69 162.5 24.946540880503 0.355076094611989 -0.3493 -0.4257 617 HSCI1_000024 COc1cc(OC)c(/C=C\2/C(=O)Nc3ccccc23)c(OC)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C11 mock treatment 206.0 10.8 0.11 201.0 48.3 0.6 139.0 1.44654088050299 0.0205893109191351 0.4206 0.6883 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C12 mock treatment 108.0 -87.2 -0.86 140.0 -12.7 -0.16 58.0 -79.553459119497 -1.13232258180942 -1.2406 -0.8679 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C13 mock treatment 177.0 -18.2 -0.18 182.0 29.3 0.36 127.0 -10.553459119497 -0.150212450966577 0.0205 0.0474 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C14 mock treatment 124.0 -71.2 -0.7 97.5 -55.2 -0.69 97.0 -40.553459119497 -0.577216855680858 -1.1348 -0.9964 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C15 mock treatment 199.0 3.83 0.04 135.5 -17.2 -0.21 122.0 -15.553459119497 -0.221379851752291 -0.2299 -0.7403 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C16 mock treatment 131.0 -64.2 -0.63 107.0 -45.7 -0.57 81.0 -56.553459119497 -0.804952538195142 -1.1582 -0.9891 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C17 compound treatment 168.5 -26.7 -0.26 164.0 11.3 0.14 157.0 19.446540880503 0.276791953747704 0.0893 0.2197 3055108 HSCI1_000025 CSCC1OC([C@@H](O)[C@H]1O)n2ccc3c(N)ncnc23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C18 compound treatment 259.0 63.8 0.63 252.5 99.8 1.24 289.0 151.446540880503 2.15561133449054 2.3247 0.9059 3055110 HSCI1_000026 ClCC(=O)c1cc(Br)c(Br)s1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C19 compound treatment 184.5 -10.7 -0.11 165.0 12.3 0.15 118.0 -19.553459119497 -0.278313772380862 -0.133 -0.3978 2121 HSCI1_000027 Oc1ccc(cc1)c2oc3cc(O)cc(O)c3c(=O)c2O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C20 compound treatment 199.0 3.83 0.04 166.0 13.3 0.17 113.5 -24.053459119497 -0.342364433088004 -0.0804 -0.2105 1916983 HSCI1_000028 CC(C)C(N1C(=O)/C(=C/c2ccccc2)/SC1=S)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C21 compound treatment 310.0 115.0 1.13 199.0 46.3 0.58 141.0 3.44654088050299 0.0490562712334205 1.0136 0.7983 2188 HSCI1_000029 Oc1ccc(O)c2C(=O)C(=C(Cl)C(=O)c12)Cl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C22 compound treatment 194.5 -0.673 -0.01 158.0 5.28 0.07 165.0 27.446540880503 0.390659795004845 0.2597 0.6554 563 HSCI1_000030 Oc1ccc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C23 compound treatment 192.0 -3.17 -0.03 132.5 -20.2 -0.25 182.0 44.446540880503 0.632628957676271 0.2018 0.2961 1031143 HSCI1_000031 CS(=O)(=O)SCCN 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 C24 mock treatment 198.0 2.83 0.03 173.0 20.3 0.25 197.0 59.446540880503 0.846131160033412 0.6504 0.7362 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D01 mock treatment 273.0 77.8 0.77 113.5 -39.2 -0.49 166.0 28.446540880503 0.404893275161988 0.394 0.3961 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D02 compound treatment 135.0 -60.2 -0.59 97.5 -55.2 -0.69 88.0 -49.553459119497 -0.705318177095143 -1.1463 -0.9972 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D03 compound treatment 151.5 -43.7 -0.43 129.0 -23.7 -0.3 117.0 -20.553459119497 -0.292547252538004 -0.5877 -0.9826 551 HSCI1_000032 CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D04 compound treatment 167.5 -27.7 -0.27 183.5 30.8 0.38 159.0 21.446540880503 0.305258914061989 0.2403 0.4286 3479696 HSCI1_000033 OC(=O)C(CCCCNC(=O)CNC(=O)c1cccc(c1)C(=O)NCC(=O)NCCCCC(NC(=O)OCc2ccc(cc2)C(F)(F)F)C(=O)O)NC(=O)OCc3ccc(cc3)C(F)(F)F 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D05 compound treatment 227.0 31.8 0.31 216.0 63.3 0.79 140.0 2.44654088050299 0.0348227910762778 0.656 0.7728 674 HSCI1_000034 CCOC(=O)c1c(C)[nH]c(/C=C/2\C(=O)Nc3ccccc23)c1C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D06 compound treatment 226.0 30.8 0.3 297.5 145.0 1.8 177.0 39.446540880503 0.561461556890558 1.5404 0.8053 146 HSCI1_000035 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D07 compound treatment 182.0 -13.2 -0.13 139.0 -13.7 -0.17 116.0 -21.553459119497 -0.306780732695147 -0.3507 -0.9367 3175981 HSCI1_000036 O=c1sn(Cc2ccccc2)c(=S)n1Cc3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D08 compound treatment 193.0 -2.17 -0.02 171.0 18.3 0.23 188.0 50.446540880503 0.718029838619128 0.5336 0.7082 1000097 HSCI1_000037 Cc1c(C)c2OC(C)(COc3ccc(CC4SC(=O)NC4=O)cc3)CCc2c(C)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D09 compound treatment 58.5 -137.0 -1.35 86.0 -66.7 -0.83 69.5 -68.053459119497 -0.968637560002283 -1.8157 -0.9792 628 HSCI1_000038 Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D10 compound treatment 179.0 -16.2 -0.16 61.0 -91.7 -1.14 112.0 -25.553459119497 -0.363714653323718 -0.9615 -0.795 3175982 HSCI1_000039 COc1ccc(Nc2nccc(NCCO)n2)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D11 mock treatment 207.0 11.8 0.12 195.5 42.8 0.53 176.0 38.446540880503 0.547228076733415 0.6908 0.8941 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D12 mock treatment 182.0 -13.2 -0.13 188.0 35.3 0.44 149.5 11.946540880503 0.170040852569133 0.277 0.5668 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D13 mock treatment 213.0 17.8 0.18 156.0 3.28 0.04 143.0 5.44654088050299 0.0775232315477059 0.1696 0.8649 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D14 mock treatment 246.0 50.8 0.5 189.0 36.3 0.45 158.0 20.446540880503 0.291025433904846 0.7177 0.9775 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D15 mock treatment 202.0 6.83 0.07 160.0 7.28 0.09 115.5 -22.053459119497 -0.313897472773718 -0.0901 -0.2701 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D16 mock treatment 189.5 -5.67 -0.06 173.0 20.3 0.25 145.5 7.94654088050299 0.113106931940563 0.1789 0.6336 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D17 compound treatment 178.0 -17.2 -0.17 165.0 12.3 0.15 123.5 -14.053459119497 -0.200029631516577 -0.1248 -0.4115 584 HSCI1_000040 Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D18 compound treatment 218.5 23.3 0.23 170.0 17.3 0.22 121.5 -16.053459119497 -0.228496591830862 0.1249 0.3211 2180 HSCI1_000041 COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C(C)C)c4n2)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D19 compound treatment 181.5 -13.7 -0.13 154.0 1.28 0.02 140.0 2.44654088050299 0.0348227910762778 -0.0484 -0.3459 3055161 HSCI1_000042 COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D20 compound treatment 165.0 -30.2 -0.3 145.0 -7.72 -0.1 131.0 -6.55345911949701 -0.0932785303380065 -0.2809 -0.862 2067 HSCI1_000043 CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D21 compound treatment 119.0 -76.2 -0.75 74.5 -78.2 -0.97 99.5 -38.053459119497 -0.541633155288002 -1.3081 -0.9737 3055164 HSCI1_000044 N/C(=C(/C#N)\c1ccccc1C(F)(F)F)/Sc2ccc(N)cc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D22 compound treatment 264.0 68.8 0.68 154.0 1.28 0.02 135.5 -2.05345911949701 -0.0292278696308644 0.3835 0.5653 2407 HSCI1_000045 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ncc(C)s3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D23 compound treatment 359.0 164.0 1.61 440.5 288.0 3.58 362.0 224.446540880503 3.19465538596196 4.8448 0.9566 550 HSCI1_000046 COC1=C(Br)[C@H](O)[C@](O)(CC#N)C=C1Br 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 D24 compound treatment 125.0 -70.2 -0.69 122.0 -30.7 -0.38 143.0 5.44654088050299 0.0775232315477059 -0.5749 -0.7246 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E01 compound treatment 96.0 -99.2 -0.98 96.5 -56.2 -0.7 125.0 -12.553459119497 -0.178679411280863 -1.071 -0.8818 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E02 mock treatment 176.0 -19.2 -0.19 143.5 -9.22 -0.11 115.0 -22.553459119497 -0.32101421285229 -0.3606 -0.9254 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E03 mock treatment 102.5 -92.7 -0.91 97.0 -55.7 -0.69 80.0 -57.553459119497 -0.819186018352284 -1.4003 -0.9939 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E04 mock treatment 201.5 6.33 0.06 176.5 23.8 0.3 126.0 -11.553459119497 -0.16444593112372 0.112 0.3252 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E05 compound treatment 163.5 -31.7 -0.31 139.0 -13.7 -0.17 124.0 -13.553459119497 -0.192912891438005 -0.39 -0.9643 2294 HSCI1_000047 CC(=O)NC(C(=O)O)C(C)(C)SN=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E06 compound treatment 171.5 -23.7 -0.23 155.5 2.78 0.03 189.0 51.446540880503 0.73226331877627 0.3082 0.4007 3175983 HSCI1_000048 CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCC/C=C/C/C=C/C\C=C\C\C=C\CCCCC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E07 compound treatment 161.0 -34.2 -0.34 155.5 2.78 0.03 117.0 -20.553459119497 -0.292547252538004 -0.3431 -0.7674 640 HSCI1_000049 O=C/1Nc2ccccc2\C1=C\c3ccc[nH]3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E08 compound treatment 108.0 -87.2 -0.86 126.5 -26.2 -0.33 84.0 -53.553459119497 -0.762252097723714 -1.124 -0.942 1907779 HSCI1_000050 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E09 mock treatment 168.0 -27.2 -0.27 218.0 65.3 0.81 206.0 68.446540880503 0.974232481447696 0.8775 0.6766 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E10 mock treatment 193.0 -2.17 -0.02 115.0 -37.7 -0.47 124.0 -13.553459119497 -0.192912891438005 -0.395 -0.777 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E11 compound treatment 240.0 44.8 0.44 214.0 61.3 0.76 193.5 55.946540880503 0.796313979483412 1.1551 0.9724 627 HSCI1_000051 C=CC(=O)c1ccc2ccccc2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E12 compound treatment 310.5 115.0 1.14 151.0 -1.72 -0.02 154.0 16.446540880503 0.234091513276276 0.7782 0.6713 536 HSCI1_000052 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E13 compound treatment 126.0 -69.2 -0.68 132.0 -20.7 -0.26 99.0 -38.553459119497 -0.548749895366573 -0.8589 -0.942 593 HSCI1_000053 Oc1ccc2ccc(=O)oc2c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E14 compound treatment 157.5 -37.7 -0.37 222.5 69.8 0.87 99.0 -38.553459119497 -0.548749895366573 -0.0292 -0.0267 3055208 HSCI1_000054 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)C(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E15 mock treatment 191.0 -4.17 -0.04 113.0 -39.7 -0.49 110.0 -27.553459119497 -0.392181613638003 -0.5358 -0.8469 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E16 mock treatment 145.0 -50.2 -0.49 163.0 10.3 0.13 138.0 0.446540880502994 0.00635583076199239 -0.2076 -0.4068 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E17 mock treatment 162.5 -32.7 -0.32 133.0 -19.7 -0.25 103.0 -34.553459119497 -0.491815974738002 -0.6114 -0.96 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E18 mock treatment 156.0 -39.2 -0.39 190.5 37.8 0.47 112.5 -25.053459119497 -0.356597913245147 -0.1568 -0.2224 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E19 compound treatment 155.0 -40.2 -0.4 166.5 13.8 0.17 180.0 42.446540880503 0.604161997361986 0.2196 0.2959 1912 HSCI1_000055 [O-][N+](=O)c1cccc2cn[nH]c12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E20 compound treatment 171.0 -24.2 -0.24 186.0 33.3 0.41 170.0 32.446540880503 0.461827195790559 0.3686 0.5546 3175984 HSCI1_000056 CCCC(=O)OCSC(=S)OC1CC2CC1C3CCCC23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E21 compound treatment 175.0 -20.2 -0.2 137.5 -15.2 -0.19 121.5 -16.053459119497 -0.228496591830862 -0.356 -0.9967 596 HSCI1_000057 CN(C)c1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E22 compound treatment 208.5 13.3 0.13 67.0 -85.7 -1.07 119.0 -18.553459119497 -0.264080292223719 -0.6931 -0.6258 564 HSCI1_000058 Oc1ccc(/C=C(\C#N)/C(=O)NCCCCc2ccccc2)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E23 compound treatment 399.0 204.0 2.01 163.5 10.8 0.13 277.5 139.946540880503 1.9919263126834 2.3859 0.843 2175 HSCI1_000059 CCCCCCCCN1C(=O)C(=C(C)C1(C)O)C(=O)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 E24 mock treatment 205.0 9.83 0.1 187.0 34.3 0.43 142.0 4.44654088050299 0.0632897513905632 0.3389 0.7662 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F01 mock treatment 281.0 85.8 0.84 84.0 -68.7 -0.86 142.0 4.44654088050299 0.0632897513905632 0.0301 0.025 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F02 compound treatment 92.0 -103.0 -1.02 93.0 -59.7 -0.74 71.0 -66.553459119497 -0.947287339766569 -1.5627 -0.9919 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F03 mock treatment 210.0 14.8 0.15 88.0 -64.7 -0.81 125.0 -12.553459119497 -0.178679411280863 -0.4843 -0.5776 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F04 mock treatment 126.0 -69.2 -0.68 100.5 -52.2 -0.65 110.0 -27.553459119497 -0.392181613638003 -0.995 -0.9755 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F05 compound treatment 217.5 22.3 0.22 179.0 26.3 0.33 131.0 -6.55345911949701 -0.0932785303380065 0.262 0.6467 2108 HSCI1_000060 COc1cc2C/C(=C\c3cc(C)c(O)c(C)c3)/C(=O)c2c(N)c1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F06 compound treatment 218.0 22.8 0.22 81.0 -71.7 -0.89 167.0 29.446540880503 0.419126755319131 -0.144 -0.1423 2303 HSCI1_000061 COc1cc2CCN3Cc4c(OC)c(O)ccc4CC3c2cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F07 compound treatment 232.0 36.8 0.36 57.5 -95.2 -1.19 134.0 -3.55345911949701 -0.0505780898665784 -0.5046 -0.4066 1967 HSCI1_000062 Brc1cccc(Nc2ncnc3cc4[nH]cnc4cc23)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F08 compound treatment 184.5 -10.7 -0.11 193.0 40.3 0.5 186.0 48.446540880503 0.689562878304842 0.6271 0.7299 1918768 HSCI1_000063 Clc1ccc(C(=O)n2nnc3ccccc23)c(Cl)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F09 mock treatment 205.0 9.83 0.1 150.5 -2.22 -0.03 124.0 -13.553459119497 -0.192912891438005 -0.0715 -0.3287 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F10 mock treatment 200.5 5.33 0.05 166.5 13.8 0.17 148.0 10.446540880503 0.148690632333419 0.2152 0.9234 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F11 compound treatment 135.0 -60.2 -0.59 96.0 -56.7 -0.71 80.5 -57.053459119497 -0.812069278273713 -1.2187 -0.992 583 HSCI1_000064 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCCO)nc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F12 compound treatment 174.0 -21.2 -0.21 128.5 -24.2 -0.3 108.5 -29.053459119497 -0.413531833873717 -0.5333 -0.9649 1085933 HSCI1_000065 COC(=O)c1ccccc1NC(=O)c2ccc(F)cc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F13 compound treatment 251.0 55.8 0.55 149.0 -3.72 -0.05 148.0 10.446540880503 0.148690632333419 0.3763 0.6589 675 HSCI1_000066 Brc1ccc2NC(=O)/C(=C\c3cc4CCCCc4[nH]3)/c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F14 compound treatment 238.5 43.3 0.43 127.0 -25.7 -0.32 109.0 -28.553459119497 -0.406415093795146 -0.1734 -0.2586 2144 HSCI1_000067 O=C(Nc1ccccc1)C2C(=O)NC(=S)NC2=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F15 mock treatment 170.0 -25.2 -0.25 128.0 -24.7 -0.31 122.5 -15.053459119497 -0.21426311167372 -0.4445 -0.9888 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F16 mock treatment 184.0 -11.2 -0.11 163.0 10.3 0.13 140.0 2.44654088050299 0.0348227910762778 0.0305 0.1771 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F17 mock treatment 185.0 -10.2 -0.1 150.0 -2.72 -0.03 117.5 -20.053459119497 -0.285430512459433 -0.2422 -0.7956 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F18 mock treatment 176.0 -19.2 -0.19 179.5 26.8 0.33 143.0 5.44654088050299 0.0775232315477059 0.1284 0.3283 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F19 compound treatment 165.0 -30.2 -0.3 111.0 -41.7 -0.52 111.5 -26.053459119497 -0.370831393402289 -0.6856 -0.9737 643 HSCI1_000068 CNc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F20 compound treatment 278.5 83.3 0.82 155.5 2.78 0.03 138.0 0.446540880502994 0.00635583076199239 0.4972 0.6056 122 HSCI1_000069 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F21 compound treatment 134.0 -61.2 -0.6 118.0 -34.7 -0.43 118.5 -19.053459119497 -0.27119703230229 -0.7539 -0.955 590 HSCI1_000070 CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F22 compound treatment 200.0 4.83 0.05 178.0 25.3 0.31 178.5 40.946540880503 0.582811777126272 0.5457 0.8217 2060831 HSCI1_000071 O=C1CCCC(=O)C1CC2C(=O)CCCC2=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F23 compound treatment 175.0 -20.2 -0.2 189.0 36.3 0.45 121.5 -16.053459119497 -0.228496591830862 0.0143 0.0263 3176054 HSCI1_000072 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1)\[N+]#[C-])/Sc2ccccc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 F24 compound treatment 166.0 -29.2 -0.29 100.5 -52.2 -0.65 95.0 -42.553459119497 -0.605683815995144 -0.891 -0.954 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G01 compound treatment 131.0 -64.2 -0.63 104.0 -48.7 -0.61 117.0 -20.553459119497 -0.292547252538004 -0.8839 -0.9572 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G02 compound treatment 144.0 -51.2 -0.5 162.0 9.28 0.12 136.5 -1.05345911949701 -0.0149943894737217 -0.2328 -0.4502 305 HSCI1_000073 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G03 mock treatment 92.0 -103.0 -1.02 104.5 -48.2 -0.6 74.5 -63.053459119497 -0.897470159216569 -1.4512 -0.979 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G04 mock treatment 140.0 -55.2 -0.54 183.0 30.3 0.38 135.0 -2.55345911949701 -0.0363446097094357 -0.1168 -0.1764 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G05 mock treatment 200.5 5.33 0.05 124.0 -28.7 -0.36 123.0 -14.553459119497 -0.207146371595148 -0.2959 -0.71 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G06 mock treatment 182.0 -13.2 -0.13 149.5 -3.22 -0.04 122.0 -15.553459119497 -0.221379851752291 -0.2258 -0.8697 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G07 compound treatment 233.0 37.8 0.37 83.0 -69.7 -0.87 116.0 -21.553459119497 -0.306780732695147 -0.4635 -0.4666 2073 HSCI1_000074 CC(=CCC/C(=C/CC/C(=C/CSc1nc[nH]n1)/C)/C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G08 compound treatment 198.0 2.83 0.03 184.0 31.3 0.39 127.0 -10.553459119497 -0.150212450966577 0.1543 0.3686 3176055 HSCI1_000075 CCOc1cc(/C=C(/C#N)\C(=O)N)cc(CSc2ccccc2)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G09 compound treatment 188.0 -7.17 -0.07 156.0 3.28 0.04 125.0 -12.553459119497 -0.178679411280863 -0.1204 -0.6127 2335 HSCI1_000076 COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G10 compound treatment 307.0 112.0 1.1 234.0 81.3 1.01 197.5 59.946540880503 0.853247900111983 1.7126 0.9947 3055275 HSCI1_000077 CC(C)(C)OC(=O)NC(CC(=O)CCl)C(=O)Cc1ccccc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G11 compound treatment 197.0 1.83 0.02 196.0 43.3 0.54 152.0 14.446540880503 0.20562455296199 0.4403 0.7628 2134 HSCI1_000078 COc1cc(O)c(cc1/C=C/C(=O)c2ccc(O)cc2)C(C)(C)C=C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G12 compound treatment 156.5 -38.7 -0.38 154.0 1.28 0.02 119.0 -18.553459119497 -0.264080292223719 -0.3631 -0.7832 3055277 HSCI1_000079 COc1cc(cc(CN(C)CCc2ccc(cc2)[N+](=O)[O-])c1O)N(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G13 compound treatment 177.5 -17.7 -0.17 165.5 12.8 0.16 126.0 -11.553459119497 -0.16444593112372 -0.1035 -0.36 1002387 HSCI1_000080 Oc1ccc(C=C(C#N)C#N)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G14 compound treatment 152.0 -43.2 -0.42 160.5 7.78 0.1 130.0 -7.55345911949701 -0.107512010495149 -0.2515 -0.5602 3176058 HSCI1_000081 C[C@@H]1[C@@H](O)[C@@]2(O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@]13O)C2(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G15 compound treatment 124.0 -71.2 -0.7 138.0 -14.7 -0.18 122.5 -15.053459119497 -0.21426311167372 -0.634 -0.8396 672 HSCI1_000082 Oc1ccc(CC(C#N)C#N)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G16 compound treatment 167.0 -28.2 -0.28 159.0 6.28 0.08 163.0 25.446540880503 0.36219283469056 0.0942 0.2034 3176059 HSCI1_000083 OCc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G17 mock treatment 181.0 -14.2 -0.14 141.0 -11.7 -0.15 86.0 -51.553459119497 -0.733785137409428 -0.5885 -0.7732 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G18 mock treatment 216.5 21.3 0.21 183.0 30.3 0.38 124.0 -13.553459119497 -0.192912891438005 0.2275 0.4813 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G19 mock treatment 203.0 7.83 0.08 157.5 4.78 0.06 129.0 -8.55345911949701 -0.121745490652292 0.0085 0.0548 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G20 mock treatment 170.0 -25.2 -0.25 154.0 1.28 0.02 163.0 25.446540880503 0.36219283469056 0.0752 0.1714 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G21 compound treatment 254.0 58.8 0.58 140.0 -12.7 -0.16 115.5 -22.053459119497 -0.313897472773718 0.0616 0.0909 3415700 HSCI1_000084 CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G22 compound treatment 252.0 56.8 0.56 228.0 75.3 0.94 245.0 107.446540880503 1.52933820757626 1.7472 0.9298 3176060 HSCI1_000085 CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]4CCCC[C@@H]4N)nc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G23 compound treatment 183.5 -11.7 -0.11 161.0 8.28 0.1 155.5 17.946540880503 0.25544173351199 0.1407 0.4713 3055326 HSCI1_000086 Cc1ccc(cc1)c2cn3c4CCCCc4sc3n2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 G24 mock treatment 297.0 102.0 1.0 186.0 33.3 0.41 139.0 1.44654088050299 0.0205893109191351 0.8299 0.765 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H01 mock treatment 204.0 8.83 0.09 147.0 -5.72 -0.07 157.0 19.446540880503 0.276791953747704 0.1688 0.5651 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H02 compound treatment 199.5 4.33 0.04 147.5 -5.22 -0.07 116.0 -21.553459119497 -0.306780732695147 -0.1901 -0.6006 1886 HSCI1_000087 NCCOB(c1ccccc1)c2ccccc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H03 mock treatment 182.0 -13.2 -0.13 160.5 7.78 0.1 141.0 3.44654088050299 0.0490562712334205 0.0094 0.0555 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H04 mock treatment 119.0 -76.2 -0.75 103.0 -49.7 -0.62 99.0 -38.553459119497 -0.548749895366573 -1.1072 -0.9916 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H05 mock treatment 177.5 -17.7 -0.17 146.0 -6.72 -0.08 147.0 9.44654088050299 0.134457152176277 -0.0711 -0.3024 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H06 mock treatment 174.0 -21.2 -0.21 154.0 1.28 0.02 146.0 8.44654088050299 0.120223672019134 -0.0417 -0.173 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H07 compound treatment 242.0 46.8 0.46 46.0 -107.0 -1.33 58.0 -79.553459119497 -1.13232258180942 -1.155 -0.6396 2278 HSCI1_000088 Oc1cc(ccc1NC(=O)Nc2ccccc2Br)[N+](=O)[O-] 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H08 compound treatment 309.0 114.0 1.12 85.0 -67.7 -0.84 209.0 71.446540880503 1.01693292191912 0.747 0.4312 1891 HSCI1_000089 Clc1oc(=O)c2ccccc2c1Cl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H09 compound treatment 335.0 140.0 1.38 150.5 -2.22 -0.03 132.0 -5.55345911949701 -0.0790450501808638 0.733 0.5316 1966 HSCI1_000090 Cn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H10 compound treatment 173.0 -22.2 -0.22 168.0 15.3 0.19 135.0 -2.55345911949701 -0.0363446097094357 -0.0371 -0.1272 3176061 HSCI1_000091 CC1(CCC2(C)O1)C(C2C(=O)O)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H11 compound treatment 100.0 -95.2 -0.94 77.0 -75.7 -0.94 102.0 -35.553459119497 -0.506049454895145 -1.3775 -0.9685 291 HSCI1_000092 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H12 compound treatment 131.0 -64.2 -0.63 145.0 -7.72 -0.1 102.5 -35.053459119497 -0.498932714816574 -0.7083 -0.8737 3055333 HSCI1_000093 O=C/1Nc2ccccc2\C1=C/c3c[nH]cn3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H13 compound treatment 115.0 -80.2 -0.79 122.0 -30.7 -0.38 123.0 -14.553459119497 -0.207146371595148 -0.7961 -0.8835 3176062 HSCI1_000094 CC[C@@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H14 compound treatment 183.5 -11.7 -0.11 137.5 -15.2 -0.19 159.0 21.446540880503 0.305258914061989 4.0E-4 0.0012 1040138 HSCI1_000095 COc1cc(C=O)c(cc1OC)[N+](=O)[O-] 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H15 compound treatment 146.5 -48.7 -0.48 104.0 -48.7 -0.61 112.5 -25.053459119497 -0.356597913245147 -0.8328 -0.9782 3176063 HSCI1_000096 CC(C)n1cnc2c(NCc3ccccc3O)nc(NCCCO)nc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H16 compound treatment 142.0 -53.2 -0.52 157.0 4.28 0.05 116.5 -21.053459119497 -0.299663992616576 -0.4444 -0.734 2109 HSCI1_000097 OCc1c[nH]c2ccccc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H17 mock treatment 194.0 -1.17 -0.01 172.5 19.8 0.25 116.0 -21.553459119497 -0.306780732695147 -0.0416 -0.1056 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H18 mock treatment 172.0 -23.2 -0.23 142.0 -10.7 -0.13 151.0 13.446540880503 0.191391072804848 -0.0983 -0.3012 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H19 mock treatment 185.0 -10.2 -0.1 142.0 -10.7 -0.13 120.0 -17.553459119497 -0.249846812066576 -0.2792 -0.9291 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H20 mock treatment 225.0 29.8 0.29 183.0 30.3 0.38 168.5 30.946540880503 0.440476975554845 0.6415 0.9871 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H21 compound treatment 241.0 45.8 0.45 158.0 5.28 0.07 130.5 -7.05345911949701 -0.100395270416578 0.2404 0.5151 3176064 HSCI1_000098 O/N=C\1/C(=C\2/C(=O)Nc3ccc(cc23)S(=O)(=O)O)/Nc4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H22 compound treatment 283.5 88.3 0.87 158.0 5.28 0.07 132.5 -5.05345911949701 -0.0719283101022925 0.4984 0.5697 2069332 HSCI1_000099 CC(=O)/C(=N/O)/C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H23 compound treatment 240.0 44.8 0.44 150.5 -2.22 -0.03 161.0 23.446540880503 0.333725874376275 0.4314 0.7789 642 HSCI1_000100 COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 H24 compound treatment 178.5 -16.7 -0.16 104.5 -48.2 -0.6 92.0 -45.553459119497 -0.648384256466572 -0.8158 -0.9076 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I01 compound treatment 158.0 -37.2 -0.37 100.5 -52.2 -0.65 89.0 -48.553459119497 -0.691084696938 -0.9858 -0.9692 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I02 compound treatment 139.0 -56.2 -0.55 104.0 -48.7 -0.61 85.0 -52.553459119497 -0.748018617566571 -1.1014 -0.9917 666 HSCI1_000101 CC(C)c1cc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc(C(C)C)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I03 compound treatment 333.0 138.0 1.36 196.0 43.3 0.54 194.0 56.446540880503 0.803430719561984 1.5583 0.9352 3176066 HSCI1_000102 CCCCC/C=C/C/C=C/C\C=C\C\C=C\CCCC(=O)C(F)(F)F 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I04 compound treatment 293.0 97.8 0.96 160.0 7.28 0.09 183.0 45.446540880503 0.646862437833414 0.9817 0.8437 2104844 HSCI1_000103 Oc1ccc(O)c(CNc2ccc(cc2)C(=O)OC3(CC4CC5CC(C4)C3)C5)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I05 mock treatment 276.0 80.8 0.8 176.0 23.3 0.29 136.0 -1.55345911949701 -0.022111129552293 0.614 0.7248 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I06 mock treatment 170.5 -24.7 -0.24 122.0 -30.7 -0.38 139.0 1.44654088050299 0.0205893109191351 -0.3492 -0.7698 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I07 mock treatment 203.0 7.83 0.08 164.0 11.3 0.14 155.5 17.946540880503 0.25544173351199 0.2731 0.9056 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I08 mock treatment 177.5 -17.7 -0.17 159.0 6.28 0.08 155.0 17.446540880503 0.248324993433418 0.0881 0.2813 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I09 compound treatment 285.5 90.3 0.89 186.0 33.3 0.41 158.5 20.946540880503 0.298142173983418 0.9247 0.902 626 HSCI1_000104 CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I10 compound treatment 202.5 7.33 0.07 175.5 22.8 0.28 130.0 -7.55345911949701 -0.107512010495149 0.1434 0.4597 3055340 HSCI1_000105 Cc1ccc(N/N=C/2\C(=O)Nc3ccc(Br)cc23)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I11 compound treatment 174.0 -21.2 -0.21 60.5 -92.2 -1.15 115.5 -22.053459119497 -0.313897472773718 -0.9647 -0.798 568 HSCI1_000106 COc1ccc(C=C(C#N)C#N)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I12 compound treatment 155.0 -40.2 -0.4 156.0 3.28 0.04 109.0 -28.553459119497 -0.406415093795146 -0.4394 -0.7728 3176067 HSCI1_000107 Ic1cccc(CSc2nnc(o2)c3ccncc3)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I13 compound treatment 178.5 -16.7 -0.16 127.0 -25.7 -0.32 96.0 -41.553459119497 -0.591450335838001 -0.6212 -0.8972 558 HSCI1_000108 Oc1ccc(C=C(C#N)C#N)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I14 compound treatment 402.5 207.0 2.04 337.0 184.0 2.3 326.5 188.946540880503 2.68936684038339 4.056 0.9936 3176068 HSCI1_000109 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I15 compound treatment 178.0 -17.2 -0.17 147.0 -5.72 -0.07 160.0 22.446540880503 0.319492394219132 0.0457 0.1241 1975 HSCI1_000110 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1c5ccc(=O)oc5 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I16 compound treatment 181.0 -14.2 -0.14 163.0 10.3 0.13 97.0 -40.553459119497 -0.577216855680858 -0.3399 -0.5595 1001980 HSCI1_000111 CCCCCCCC/C=C/CCCCCCCC(=O)OCC(CO)OC(=O)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I17 compound treatment 187.0 -8.17 -0.08 154.0 1.28 0.02 146.0 8.44654088050299 0.120223672019134 0.0322 0.221 130 HSCI1_000112 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I18 compound treatment 184.0 -11.2 -0.11 139.0 -13.7 -0.17 115.0 -22.553459119497 -0.32101421285229 -0.3475 -0.9146 1922639 HSCI1_000113 CC(C)C(N1C(=O)/C(=C/c2ccc(Br)cc2)/SC1=S)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I19 mock treatment 146.0 -49.2 -0.48 165.5 12.8 0.16 100.0 -37.553459119497 -0.53451641520943 -0.4962 -0.6719 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I20 mock treatment 183.0 -12.2 -0.12 172.0 19.3 0.24 171.0 33.446540880503 0.476060675947702 0.3443 0.63 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I21 mock treatment 173.0 -22.2 -0.22 163.0 10.3 0.13 126.0 -11.553459119497 -0.16444593112372 -0.147 -0.4873 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I22 mock treatment 173.0 -22.2 -0.22 140.0 -12.7 -0.16 141.5 3.94654088050299 0.0561730113119919 -0.1851 -0.6717 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I23 compound treatment 156.0 -39.2 -0.39 126.0 -26.7 -0.33 116.0 -21.553459119497 -0.306780732695147 -0.5919 -0.9954 565 HSCI1_000114 Oc1cc(C=C(C#N)C#N)cc(O)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 I24 mock treatment 274.0 78.8 0.78 211.5 58.8 0.73 164.0 26.446540880503 0.376426314847703 1.088 0.9618 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J01 mock treatment 268.5 73.3 0.72 159.0 6.28 0.08 142.0 4.44654088050299 0.0632897513905632 0.4984 0.6839 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J02 compound treatment 226.0 30.8 0.3 158.0 5.28 0.07 138.0 0.446540880502994 0.00635583076199239 0.2168 0.6982 3176070 HSCI1_000115 OC(=O)c1c(Br)c(Br)c(Br)c(Br)c1c2c3ccc(O)cc3oc4cc(=O)ccc24 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J03 compound treatment 224.5 29.3 0.29 143.0 -9.72 -0.12 138.0 0.446540880502994 0.00635583076199239 0.1004 0.3207 294 HSCI1_000116 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J04 compound treatment 235.0 39.8 0.39 130.0 -22.7 -0.28 121.0 -16.553459119497 -0.235613331909434 -0.0731 -0.1359 3055387 HSCI1_000117 C[C@@]12CCC3C(CCC4=C[C@H](O)CCC34)C2CC[C@@H]1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J05 mock treatment 214.0 18.8 0.19 156.5 3.78 0.05 175.0 37.446540880503 0.532994596576272 0.4419 0.7804 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J06 mock treatment 214.0 18.8 0.19 171.0 18.3 0.23 167.0 29.446540880503 0.419126755319131 0.4804 0.9389 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J07 mock treatment 230.5 35.3 0.35 158.0 5.28 0.07 105.0 -32.553459119497 -0.463349014423717 -0.0288 -0.0494 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J08 mock treatment 292.0 96.8 0.95 171.5 18.8 0.23 202.0 64.446540880503 0.917298560819125 1.2149 0.9044 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J09 compound treatment 209.0 13.8 0.14 160.5 7.78 0.1 130.0 -7.55345911949701 -0.107512010495149 0.0724 0.3646 633 HSCI1_000118 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3ccccc3O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J10 compound treatment 158.0 -37.2 -0.37 222.0 69.3 0.86 148.0 10.446540880503 0.148690632333419 0.3728 0.3928 2251 HSCI1_000119 O=C(NC1=CC(=O)c2ccccc2C1=O)c3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J11 compound treatment 334.0 139.0 1.37 218.0 65.3 0.81 165.5 27.946540880503 0.397776535083417 1.488 0.9078 645 HSCI1_000120 Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J12 compound treatment 319.0 124.0 1.22 215.0 62.3 0.78 153.0 15.446540880503 0.219858033119133 1.2785 0.8748 3176071 HSCI1_000121 Nc1nc(Cl)nc2n(cnc12)C3C[C@@H](O)C(CO)O3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J13 compound treatment 253.0 57.8 0.57 159.5 6.78 0.08 138.5 0.946540880502994 0.0134725708405637 0.3851 0.6691 646 HSCI1_000122 CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J14 compound treatment 181.5 -13.7 -0.13 148.0 -4.72 -0.06 129.0 -8.55345911949701 -0.121745490652292 -0.1819 -0.9537 854065 HSCI1_000123 CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J15 compound treatment 152.0 -43.2 -0.42 102.5 -50.2 -0.63 95.0 -42.553459119497 -0.605683815995144 -0.9562 -0.9869 670 HSCI1_000124 CN(C)S(=O)(=O)c1ccc2NC(=O)/C(=C\c3cc4CCCCc4[nH]3)/c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J16 compound treatment 215.0 19.8 0.2 163.0 10.3 0.13 164.5 26.946540880503 0.383543054926274 0.408 0.9088 3176072 HSCI1_000125 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)c4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J17 compound treatment 323.5 128.0 1.26 283.0 130.0 1.62 227.0 89.446540880503 1.27313556474769 2.4011 0.9928 1996 HSCI1_000126 CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J18 compound treatment 180.0 -15.2 -0.15 148.0 -4.72 -0.06 80.0 -57.553459119497 -0.819186018352284 -0.5931 -0.7105 2268 HSCI1_000127 CC(=CC1C(C(=O)OCc2coc(Cc3ccccc3)c2)C1(C)C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J19 mock treatment 182.5 -12.7 -0.12 184.5 31.8 0.4 166.0 28.446540880503 0.404893275161988 0.3903 0.6731 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J20 mock treatment 209.0 13.8 0.14 154.0 1.28 0.02 118.0 -19.553459119497 -0.278313772380862 -0.0729 -0.235 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J21 mock treatment 193.0 -2.17 -0.02 211.5 58.8 0.73 160.0 22.446540880503 0.319492394219132 0.5948 0.7444 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J22 mock treatment 153.0 -42.2 -0.42 109.0 -43.7 -0.54 80.0 -57.553459119497 -0.819186018352284 -1.027 -0.9619 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J23 compound treatment 260.0 64.8 0.64 138.0 -14.7 -0.18 116.0 -21.553459119497 -0.306780732695147 0.0854 0.1168 654 HSCI1_000128 CC(C)C(CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 J24 compound treatment 162.5 -32.7 -0.32 91.0 -61.7 -0.77 85.0 -52.553459119497 -0.748018617566571 -1.0614 -0.9478 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K01 compound treatment 130.0 -65.2 -0.64 91.5 -61.2 -0.76 92.0 -45.553459119497 -0.648384256466572 -1.1849 -0.9967 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K02 compound treatment 193.5 -1.67 -0.02 146.5 -6.22 -0.08 143.5 5.94654088050299 0.0846399716262773 -0.0054 -0.0464 3055432 HSCI1_000129 CCOC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cc(OC)c(OC)c(OC)c2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K03 compound treatment 218.0 22.8 0.22 148.0 -4.72 -0.06 114.0 -23.553459119497 -0.335247693009433 -0.0978 -0.2398 570 HSCI1_000130 NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K04 compound treatment 336.0 141.0 1.39 227.0 74.3 0.93 171.5 33.946540880503 0.483177416026273 1.6134 0.9298 1005921 HSCI1_000131 OCC1OC(Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)C(O)C(O)C1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K05 compound treatment 188.0 -7.17 -0.07 151.0 -1.72 -0.02 125.0 -12.553459119497 -0.178679411280863 -0.1563 -0.8085 559 HSCI1_000132 OC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K06 compound treatment 272.0 76.8 0.76 134.0 -18.7 -0.23 238.5 100.946540880503 1.43682058655483 1.1315 0.6898 620 HSCI1_000133 COc1cc(/C=C(\C#N)/C(=O)c2ccc(O)c(O)c2)cc(I)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K07 mock treatment 216.0 20.8 0.21 146.0 -6.72 -0.08 119.0 -18.553459119497 -0.264080292223719 -0.0824 -0.2392 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K08 mock treatment 197.0 1.83 0.02 155.5 2.78 0.03 203.0 65.446540880503 0.931532040976268 0.5682 0.6094 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K09 mock treatment 205.0 9.83 0.1 146.5 -6.22 -0.08 128.0 -9.55345911949701 -0.135978970809435 -0.0674 -0.3663 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K10 mock treatment 198.0 2.83 0.03 145.0 -7.72 -0.1 126.0 -11.553459119497 -0.16444593112372 -0.1344 -0.6981 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K11 compound treatment 164.0 -31.2 -0.31 136.0 -16.7 -0.21 122.0 -15.553459119497 -0.221379851752291 -0.4252 -0.9845 553 HSCI1_000134 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K12 compound treatment 140.0 -55.2 -0.54 124.5 -28.2 -0.35 93.0 -44.553459119497 -0.634150776309429 -0.8826 -0.9743 3176129 HSCI1_000135 Oc1cc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc(I)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K13 compound treatment 156.5 -38.7 -0.38 139.0 -13.7 -0.17 119.0 -18.553459119497 -0.264080292223719 -0.4709 -0.9536 1000035 HSCI1_000136 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K14 compound treatment 171.0 -24.2 -0.24 148.5 -4.22 -0.05 115.0 -22.553459119497 -0.32101421285229 -0.3531 -0.876 1 HSCI1_000137 Oc1ccc(/C=C(\C#N)/C(=O)NCCCNC(=O)\C(=C\c2ccc(O)c(O)c2)\C#N)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K15 mock treatment 154.0 -41.2 -0.41 152.5 -0.222 0.0 141.0 3.44654088050299 0.0490562712334205 -0.2073 -0.5077 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K16 mock treatment 194.0 -1.17 -0.01 169.0 16.3 0.2 154.0 16.446540880503 0.234091513276276 0.2455 0.7923 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K17 compound treatment 199.0 3.83 0.04 138.0 -14.7 -0.18 124.0 -13.553459119497 -0.192912891438005 -0.1955 -0.7273 554 HSCI1_000138 Oc1cc(C=C(C#N)C#N)cc([N+](=O)[O-])c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K18 compound treatment 171.0 -24.2 -0.24 161.0 8.28 0.1 120.5 -17.053459119497 -0.242730071988005 -0.218 -0.6137 3176130 HSCI1_000139 CN(C)c1ccc2c(c3ccccc3C(=O)O)c4ccc(=[N+](C)C)cc4oc2c1.CC(=O)NCCSS(=O)(=O)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K19 compound treatment 21.0 -174.0 -1.71 15.0 -138.0 -1.72 79.0 -58.553459119497 -0.833419498509427 -2.4613 -0.9598 555 HSCI1_000140 Cc1cc2ncc(nc2cc1C)c3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K20 compound treatment 173.0 -22.2 -0.22 150.0 -2.72 -0.03 122.0 -15.553459119497 -0.221379851752291 -0.2734 -0.8743 2311 HSCI1_000141 COC(=O)c1c(c2cc(OC)c(OC)c(OC)c2)c3ccnc(OCc4ncccn4)c3c(=O)n1Cc5ccnc(C)c5 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K21 mock treatment 257.5 62.3 0.61 179.0 26.3 0.33 125.5 -12.053459119497 -0.171562671202291 0.4441 0.6201 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K22 mock treatment 261.0 65.8 0.65 165.0 12.3 0.15 127.0 -10.553459119497 -0.150212450966577 0.3757 0.5504 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K23 compound treatment 141.0 -54.2 -0.53 92.0 -60.7 -0.76 67.0 -70.553459119497 -1.00422126039514 -1.3243 -0.9698 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 K24 mock treatment 264.5 69.3 0.68 183.0 30.3 0.38 165.5 27.946540880503 0.397776535083417 0.8414 0.9613 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L01 mock treatment 251.5 56.3 0.55 197.0 44.3 0.55 152.0 14.446540880503 0.20562455296199 0.7572 0.9365 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L02 compound treatment 216.0 20.8 0.21 157.0 4.28 0.05 132.0 -5.55345911949701 -0.0790450501808638 0.1035 0.4577 1995 HSCI1_000142 CN(C1CCCCC1)C(=O)CCCOc2ccc3[nH]c(=O)ccc3c2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L03 compound treatment 152.0 -43.2 -0.42 200.0 47.3 0.59 96.5 -41.053459119497 -0.58433359575943 -0.2427 -0.2604 3176131 HSCI1_000143 Nc1ncnc2n(cc(I)c12)C3OC(CO)[C@H](O)[C@@H]3O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L04 compound treatment 194.0 -1.17 -0.01 161.0 8.28 0.1 153.0 15.446540880503 0.219858033119133 0.1798 0.7396 3055484 HSCI1_000144 COc1cc(SC)ccc1c2nc3ccncc3[nH]2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L05 compound treatment 278.0 82.8 0.82 176.0 23.3 0.29 201.0 63.446540880503 0.903065080661983 1.1595 0.9271 1907775 HSCI1_000145 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L06 compound treatment 171.0 -24.2 -0.24 165.0 12.3 0.15 139.0 1.44654088050299 0.0205893109191351 -0.0372 -0.1312 3176132 HSCI1_000146 COc1ccc(cc1)C(=C2C(=O)Nc3ccccc23)c4ccc(OC)cc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L07 mock treatment 240.0 44.8 0.44 166.0 13.3 0.17 152.0 14.446540880503 0.20562455296199 0.4689 0.9121 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L08 mock treatment 210.5 15.3 0.15 197.0 44.3 0.55 181.5 43.946540880503 0.6255122175977 0.7666 0.9047 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L09 mock treatment 234.0 38.8 0.38 172.0 19.3 0.24 133.0 -4.55345911949701 -0.0648115700237211 0.3219 0.7059 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L10 mock treatment 239.0 43.8 0.43 164.0 11.3 0.14 142.0 4.44654088050299 0.0632897513905632 0.3667 0.8005 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L11 compound treatment 175.0 -20.2 -0.2 135.0 -17.7 -0.22 111.0 -26.553459119497 -0.377948133480861 -0.4603 -0.9577 3055486 HSCI1_000147 O=C1NC(=O)c2c1c3c4ccccc4n5C6CCC(O6)n7c8ccccc8c2c7c53 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L12 compound treatment 235.0 39.8 0.39 123.5 -29.2 -0.36 128.0 -9.55345911949701 -0.135978970809435 -0.0623 -0.1129 3176133 HSCI1_000148 OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L13 compound treatment 127.5 -67.7 -0.67 164.0 11.3 0.14 170.0 32.446540880503 0.461827195790559 -0.0368 -0.0448 3176134 HSCI1_000149 O/N=C\1/C(=C\2/C(=O)Nc3ccc(I)cc23)/Nc4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L14 compound treatment 183.0 -12.2 -0.12 152.0 -0.722 -0.01 135.5 -2.05345911949701 -0.0292278696308644 -0.0912 -0.7379 3055490 HSCI1_000150 COc1cc(ccc1c2nc3ccncc3[nH]2)S(=O)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L15 mock treatment 198.0 2.83 0.03 187.0 34.3 0.43 134.5 -3.05345911949701 -0.0434613497880071 0.2375 0.5522 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L16 mock treatment 198.0 2.83 0.03 177.0 24.3 0.3 160.0 22.446540880503 0.319492394219132 0.3751 0.851 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L17 compound treatment 248.5 53.3 0.52 153.5 0.778 0.01 106.0 -31.553459119497 -0.449115534266574 0.0494 0.0714 3176135 HSCI1_000151 C[S+](O)c1ccc(CSc2nc(c([nH]2)c3ccc(F)cc3)c4ccncc4)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L18 compound treatment 162.0 -33.2 -0.33 102.0 -50.7 -0.63 142.5 4.94654088050299 0.0704064914691346 -0.5126 -0.7173 2109556 HSCI1_000152 Nc1n[nH]c2nc3ccccc3nc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L19 compound treatment 247.5 52.3 0.52 151.0 -1.72 -0.02 145.0 7.44654088050299 0.105990191861991 0.3462 0.6578 3176136 HSCI1_000153 C[C@@H]1C2NCC(C)C[C@H]2O[C@@]31CCC4C5CC=C6CC(O)CCC6(C)C5C(=O)C4=C3C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L20 compound treatment 220.0 24.8 0.24 131.0 -21.7 -0.27 112.0 -25.553459119497 -0.363714653323718 -0.2251 -0.4371 3055494 HSCI1_000154 OB(O)c1ccc(cc1)C(=O)/C=C/c2ccc(I)cc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L21 mock treatment 234.0 38.8 0.38 148.0 -4.72 -0.06 115.5 -22.053459119497 -0.313897472773718 0.0055 0.011 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L22 mock treatment 178.0 -17.2 -0.17 110.5 -42.2 -0.53 98.0 -39.553459119497 -0.562983375523716 -0.7262 -0.9208 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L23 mock treatment 311.0 116.0 1.14 185.5 32.8 0.41 135.0 -2.55345911949701 -0.0363446097094357 0.873 0.7205 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 L24 compound treatment 219.5 24.3 0.24 112.0 -40.7 -0.51 158.0 20.446540880503 0.291025433904846 0.0134 0.0213 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M01 compound treatment 120.0 -75.2 -0.74 103.0 -49.7 -0.62 115.0 -22.553459119497 -0.32101421285229 -0.9701 -0.954 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M02 compound treatment 282.0 86.8 0.85 196.0 43.3 0.54 142.0 4.44654088050299 0.0632897513905632 0.8412 0.8309 2095175 HSCI1_000155 Oc1ccc(/C=C(\C#N)/C(=O)NC2CCC(CC3CCC(CC3)NC(=O)\C(=C\c4ccc(O)c(O)c4)\C#N)CC2)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M03 compound treatment 273.0 77.8 0.77 126.0 -26.7 -0.33 130.0 -7.55345911949701 -0.107512010495149 0.1881 0.2233 552 HSCI1_000156 NC(=C(C#N)C#N)/C(=C/c1ccc(O)cc1)/C#N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M04 compound treatment 183.0 -12.2 -0.12 165.5 12.8 0.16 114.0 -23.553459119497 -0.335247693009433 -0.1708 -0.4381 613 HSCI1_000157 Oc1cc(/C=C/c2ccc(O)c(O)c2)oc(=O)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M05 compound treatment 146.0 -49.2 -0.48 145.0 -7.72 -0.1 112.0 -25.553459119497 -0.363714653323718 -0.545 -0.889 657 HSCI1_000158 COc1ccc(/C=C(\C#N)/c2cccnc2)cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M06 compound treatment 265.0 69.8 0.69 233.0 80.3 1.0 232.0 94.446540880503 1.34430296553341 1.7502 0.9665 3176139 HSCI1_000159 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCCC)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M07 compound treatment 220.0 24.8 0.24 172.0 19.3 0.24 139.5 1.94654088050299 0.0277060509977064 0.2957 0.8603 671 HSCI1_000160 NC(=C(C#N)C#N)/C(=C/c1cc(O)c(O)c(O)c1)/C#N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M08 compound treatment 225.0 29.8 0.29 174.5 21.8 0.27 127.0 -10.553459119497 -0.150212450966577 0.2394 0.5606 3176140 HSCI1_000161 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)[C@@H]3S 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M09 mock treatment 154.5 -40.7 -0.4 131.0 -21.7 -0.27 107.0 -30.553459119497 -0.434882054109431 -0.6384 -0.9821 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M10 mock treatment 167.0 -28.2 -0.28 185.0 32.3 0.4 177.0 39.446540880503 0.561461556890558 0.3962 0.5324 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M11 mock treatment 145.0 -50.2 -0.49 170.0 17.3 0.22 153.0 15.446540880503 0.219858033119133 -0.0339 -0.0583 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M12 mock treatment 194.0 -1.17 -0.01 162.0 9.28 0.12 116.0 -21.553459119497 -0.306780732695147 -0.1171 -0.3569 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M13 mock treatment 168.5 -26.7 -0.26 132.5 -20.2 -0.25 114.0 -23.553459119497 -0.335247693009433 -0.4905 -0.9916 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M14 mock treatment 184.0 -11.2 -0.11 143.0 -9.72 -0.12 116.5 -21.053459119497 -0.299663992616576 -0.3064 -0.8975 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M15 compound treatment 150.0 -45.2 -0.44 115.5 -37.2 -0.46 98.0 -39.553459119497 -0.562983375523716 -0.8494 -0.9944 585 HSCI1_000162 Oc1ccc(C(=O)/C=C/c2ccc(O)c(O)c2)c(O)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M16 compound treatment 271.5 76.3 0.75 391.0 238.0 2.97 142.0 4.44654088050299 0.0632897513905632 2.1837 0.7132 2024 HSCI1_000163 CN(N=O)c1cc(O)ccc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M17 compound treatment 313.0 118.0 1.16 224.5 71.8 0.89 167.0 29.446540880503 0.419126755319131 1.4277 0.9374 569 HSCI1_000164 COC(=O)c1ccc(NCc2cc(O)ccc2O)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M18 compound treatment 144.0 -51.2 -0.5 150.0 -2.72 -0.03 98.0 -39.553459119497 -0.562983375523716 -0.6354 -0.8403 1890 HSCI1_000165 CN(N=O)c1ccc(O)c(O)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M19 compound treatment 143.0 -52.2 -0.51 162.0 9.28 0.12 118.0 -19.553459119497 -0.278313772380862 -0.3905 -0.6558 1008455 HSCI1_000166 BrCC(=O)c1ccc(Br)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M20 compound treatment 146.0 -49.2 -0.48 187.0 34.3 0.43 161.0 23.446540880503 0.333725874376275 0.1597 0.2198 3176141 HSCI1_000167 CCN(N=O)c1ccc(O)c(O)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M21 compound treatment 233.5 38.3 0.38 136.5 -16.2 -0.2 126.0 -11.553459119497 -0.16444593112372 0.0062 0.0136 560 HSCI1_000168 Oc1ccc(/C=C(\C#N)/C(=O)Nc2ccccc2)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M22 compound treatment 182.5 -12.7 -0.12 186.0 33.3 0.41 154.0 16.446540880503 0.234091513276276 0.3024 0.6146 566 HSCI1_000169 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M23 compound treatment 111.5 -83.7 -0.82 99.5 -53.2 -0.66 79.0 -58.553459119497 -0.833419498509427 -1.3394 -0.9949 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 M24 mock treatment 173.0 -22.2 -0.22 179.0 26.3 0.33 136.5 -1.05345911949701 -0.0149943894737217 0.0543 0.1379 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N01 mock treatment 229.5 34.3 0.34 119.0 -33.7 -0.42 109.0 -28.553459119497 -0.406415093795146 -0.2821 -0.4178 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N02 compound treatment 239.0 43.8 0.43 75.0 -77.7 -0.97 134.0 -3.55345911949701 -0.0505780898665784 -0.339 -0.3195 837968 HSCI1_000170 Nc1ncnc2n(cnc12)C3CCCO3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N03 compound treatment 176.0 -19.2 -0.19 100.0 -52.7 -0.66 148.0 10.446540880503 0.148690632333419 -0.4022 -0.5752 3176143 HSCI1_000171 CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)CCC(=O)O)[C@@]3(C)O[C@](C)(CC(=O)[C@@]32O)C=C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N04 compound treatment 213.0 17.8 0.18 167.0 14.3 0.18 142.0 4.44654088050299 0.0632897513905632 0.2405 0.9333 831810 HSCI1_000172 Brc1c(Br)c(Br)c2[nH]nnc2c1Br 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N05 compound treatment 190.0 -5.17 -0.05 122.5 -30.2 -0.38 165.0 27.446540880503 0.390659795004845 -0.0212 -0.0389 3054768 HSCI1_000173 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C\[C@H](O)CCC[C@@H](C)C/C=C\[C@H]4C(=O)C1=C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N06 compound treatment 363.5 168.0 1.66 253.0 100.0 1.25 218.0 80.446540880503 1.14503424333341 2.3387 0.9869 3054769 HSCI1_000174 Cn1sc(=O)n(Cc2ccccc2)c1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N07 compound treatment 219.0 23.8 0.23 187.0 34.3 0.43 162.5 24.946540880503 0.355076094611989 0.5869 0.9736 621 HSCI1_000175 CS(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4cccc(I)c4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N08 compound treatment 196.0 0.827 0.01 145.0 -7.72 -0.1 137.0 -0.553459119497006 -0.00787764939515031 -0.0554 -0.5718 3054770 HSCI1_000176 c1ccc(cc1)c2n[nH]c3c2oc4ccccc34 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N09 mock treatment 171.0 -24.2 -0.24 206.5 53.8 0.67 160.0 22.446540880503 0.319492394219132 0.4338 0.5566 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N10 mock treatment 108.0 -87.2 -0.86 97.0 -55.7 -0.69 98.0 -39.553459119497 -0.562983375523716 -1.2211 -0.9857 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N11 mock treatment 164.5 -30.7 -0.3 123.0 -29.7 -0.37 117.5 -20.053459119497 -0.285430512459433 -0.5528 -0.9935 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N12 mock treatment 80.5 -115.0 -1.13 95.0 -57.7 -0.72 95.0 -42.553459119497 -0.605683815995144 -1.4164 -0.9643 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N13 mock treatment 181.0 -14.2 -0.14 169.0 16.3 0.2 102.0 -35.553459119497 -0.506049454895145 -0.2557 -0.4543 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N14 mock treatment 118.5 -76.7 -0.75 89.0 -63.7 -0.79 94.0 -43.553459119497 -0.619917296152287 -1.2518 -0.9947 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N15 compound treatment 152.0 -43.2 -0.42 154.5 1.78 0.02 101.0 -36.553459119497 -0.520282935052288 -0.5329 -0.7929 3176144 HSCI1_000177 CC1C2C(Cc3ccccc3)NC(=O)C42OC(=O)O/C=C\C(C)(O)C(=O)C(C)C/C=C\C4C5OC51C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N16 compound treatment 170.0 -25.2 -0.25 158.5 5.78 0.07 147.0 9.44654088050299 0.134457152176277 -0.0239 -0.0821 1056418 HSCI1_000178 Nc1ncnc2n(cnc12)C3CCC(CO)O3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N17 compound treatment 181.0 -14.2 -0.14 166.0 13.3 0.17 120.0 -17.553459119497 -0.249846812066576 -0.1293 -0.3913 2177 HSCI1_000179 CC(C)CC[C@@H](O)[C@](C)(O)C1CC[C@@]2(O)C3=CC(=O)[C@]4(O)C[C@@H](O)[C@@H](O)C[C@]4(C)C3[C@H](O)C[C@]12C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N18 compound treatment 224.0 28.8 0.28 205.0 52.3 0.65 125.0 -12.553459119497 -0.178679411280863 0.4366 0.5961 3054771 HSCI1_000180 COc1ccc2NC(=O)/C(=C\c3c[nH]cn3)/c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N19 compound treatment 276.0 80.8 0.8 215.0 62.3 0.78 169.0 31.446540880503 0.447593715633416 1.1656 0.973 3176146 HSCI1_000181 CCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCC)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N20 compound treatment 340.0 145.0 1.43 455.5 303.0 3.77 242.0 104.446540880503 1.48663776710483 3.8586 0.898 2127 HSCI1_000182 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N21 compound treatment 342.0 147.0 1.45 222.0 69.3 0.86 162.0 24.446540880503 0.347959354533417 1.5335 0.8922 3054772 HSCI1_000183 CC(C)(O)/C=C/C(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4C(C=C(O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@@]12C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N22 compound treatment 174.0 -21.2 -0.21 144.5 -8.22 -0.1 122.0 -15.553459119497 -0.221379851752291 -0.3073 -0.9577 1937872 HSCI1_000184 [O-][N+](=O)c1ccccc1c2ccc(C=C3C(=O)N(C(=S)N(C3=O)c4ccccc4)c5ccccc5)o2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N23 mock treatment 174.0 -21.2 -0.21 253.5 101.0 1.26 163.5 25.946540880503 0.369309574769131 0.8176 0.6171 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 N24 compound treatment 110.5 -84.7 -0.83 91.0 -61.7 -0.77 81.5 -56.053459119497 -0.79783579811657 -1.3856 -0.9995 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O01 compound treatment 211.0 15.8 0.16 105.0 -47.7 -0.59 89.0 -48.553459119497 -0.691084696938 -0.6522 -0.7053 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O02 mock treatment 207.0 11.8 0.12 186.0 33.3 0.41 149.0 11.446540880503 0.162924112490562 0.4006 0.8702 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O03 compound treatment 139.0 -56.2 -0.55 118.0 -34.7 -0.43 101.0 -36.553459119497 -0.520282935052288 -0.8693 -0.9949 5 HSCI1_000185 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O04 compound treatment 426.0 231.0 2.27 299.0 146.0 1.82 208.0 70.446540880503 1.00269944176198 2.9425 0.9553 2090 HSCI1_000186 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O05 compound treatment 207.0 11.8 0.12 139.0 -13.7 -0.17 174.0 36.446540880503 0.51876111641913 0.268 0.48 2107241 HSCI1_000187 ClC1=C(N2C(=O)CCC2=O)C(=O)c3ccccc3C1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O06 compound treatment 238.0 42.8 0.42 160.0 7.28 0.09 129.0 -8.55345911949701 -0.121745490652292 0.2254 0.5031 651 HSCI1_000188 Nc1ncnc2n(ncc12)c3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O07 compound treatment 159.0 -36.2 -0.36 155.0 2.28 0.03 128.0 -9.55345911949701 -0.135978970809435 -0.2677 -0.7004 562 HSCI1_000189 Oc1ccc(/C=C(\C#N)/C(=O)c2ccc(O)c(O)c2)cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O08 compound treatment 205.0 9.83 0.1 99.0 -53.7 -0.67 170.0 32.446540880503 0.461827195790559 -0.0638 -0.0779 3176147 HSCI1_000190 CS/C(=C(\C#N)/C(=C(\N)/SC)/[N+]#[C-])/N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O09 compound treatment 248.0 52.8 0.52 184.0 31.3 0.39 163.0 25.446540880503 0.36219283469056 0.7342 0.9871 3176148 HSCI1_000191 OCc1cc2ncnc(Nc3ccc(O)cc3)c2cc1CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O10 compound treatment 239.0 43.8 0.43 192.0 39.3 0.49 177.0 39.446540880503 0.561461556890558 0.8557 0.9942 3054774 HSCI1_000192 Nc1ccc(cc1)c2cc(=O)c3cc(O)ccc3o2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O11 mock treatment 143.0 -52.2 -0.51 88.0 -64.7 -0.81 86.0 -51.553459119497 -0.733785137409428 -1.1855 -0.9839 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O12 mock treatment 229.5 34.3 0.34 250.0 97.3 1.21 114.0 -23.553459119497 -0.335247693009433 0.701 0.5385 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O13 mock treatment 206.0 10.8 0.11 100.5 -52.2 -0.65 121.0 -16.553459119497 -0.235613331909434 -0.45 -0.6429 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O14 mock treatment 150.5 -44.7 -0.44 172.0 19.3 0.24 97.0 -40.553459119497 -0.577216855680858 -0.4485 -0.5868 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O15 compound treatment 308.5 113.0 1.12 130.0 -22.7 -0.28 246.0 108.446540880503 1.5435716877334 1.3718 0.7125 3176208 HSCI1_000193 COc1ccc(N=O)c(CCc2cc(OC)ccc2N=O)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O16 compound treatment 184.0 -11.2 -0.11 139.0 -13.7 -0.17 147.0 9.44654088050299 0.134457152176277 -0.0845 -0.3469 3054775 HSCI1_000194 CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)OCCF 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O17 compound treatment 303.5 108.0 1.07 286.0 133.0 1.66 231.5 93.946540880503 1.33718622545484 2.346 0.9843 1860 HSCI1_000195 CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O18 compound treatment 226.5 31.3 0.31 195.0 42.3 0.53 193.0 55.446540880503 0.789197239404841 0.9377 0.9399 634 HSCI1_000196 OC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O19 compound treatment 202.0 6.83 0.07 134.0 -18.7 -0.23 130.0 -7.55345911949701 -0.107512010495149 -0.1579 -0.5949 589 HSCI1_000197 Nc1cc(Nc2ccc(cc2)S(=O)(=O)N)ncn1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O20 compound treatment 212.0 16.8 0.17 117.0 -35.7 -0.44 116.5 -21.053459119497 -0.299663992616576 -0.3343 -0.5954 3054776 HSCI1_000198 Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O21 compound treatment 235.0 39.8 0.39 187.0 34.3 0.43 108.5 -29.053459119497 -0.413531833873717 0.2341 0.3287 557 HSCI1_000199 Cc1cc2ncc(nc2cc1C)c3ccc(O)c(O)c3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O22 compound treatment 94.5 -101.0 -0.99 72.0 -80.7 -1.01 58.0 -79.553459119497 -1.13232258180942 -1.8063 -0.9982 1000586 HSCI1_000200 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O23 compound treatment 154.0 -41.2 -0.41 130.0 -22.7 -0.28 111.0 -26.553459119497 -0.377948133480861 -0.6156 -0.9893 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 O24 mock treatment 162.0 -33.2 -0.33 154.5 1.78 0.02 163.0 25.446540880503 0.36219283469056 0.0334 0.0684 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P01 mock treatment 213.0 17.8 0.18 148.0 -4.72 -0.06 146.0 8.44654088050299 0.120223672019134 0.1368 0.6197 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P02 compound treatment 122.0 -73.2 -0.72 87.5 -65.2 -0.81 84.0 -53.553459119497 -0.762252097723714 -1.3249 -0.9988 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P03 mock treatment 210.0 14.8 0.15 128.0 -24.7 -0.31 123.5 -14.053459119497 -0.200029631516577 -0.209 -0.5289 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P04 mock treatment 244.0 48.8 0.48 138.5 -14.2 -0.18 119.0 -18.553459119497 -0.264080292223719 0.0227 0.0395 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P05 mock treatment 224.5 29.3 0.29 146.0 -6.72 -0.08 112.0 -25.553459119497 -0.363714653323718 -0.0917 -0.1943 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P06 mock treatment 208.5 13.3 0.13 150.0 -2.72 -0.03 126.0 -11.553459119497 -0.16444593112372 -0.0388 -0.182 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P07 mock treatment 205.0 9.83 0.1 197.0 44.3 0.55 198.0 60.446540880503 0.860364640190555 0.871 0.8485 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P08 mock treatment 182.0 -13.2 -0.13 208.0 55.3 0.69 191.0 53.446540880503 0.760730279090556 0.7618 0.7367 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P09 mock treatment 289.0 93.8 0.92 149.5 -3.22 -0.04 147.0 9.44654088050299 0.134457152176277 0.5877 0.6291 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P10 mock treatment 189.0 -6.17 -0.06 149.0 -3.72 -0.05 153.5 15.946540880503 0.226974773197704 0.0692 0.2889 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P11 mock treatment 425.0 230.0 2.26 133.5 -19.2 -0.24 154.0 16.446540880503 0.234091513276276 1.303 0.5698 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P12 mock treatment 213.0 17.8 0.18 141.0 -11.7 -0.15 165.0 27.446540880503 0.390659795004845 0.2426 0.5361 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P13 mock treatment 222.0 26.8 0.26 170.0 17.3 0.22 196.0 58.446540880503 0.831897679876269 0.757 0.8421 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P14 mock treatment 240.0 44.8 0.44 155.0 2.28 0.03 165.0 27.446540880503 0.390659795004845 0.4967 0.8418 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P15 mock treatment 236.0 40.8 0.4 185.5 32.8 0.41 180.0 42.446540880503 0.604161997361986 0.8165 0.9807 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P16 mock treatment 209.0 13.8 0.14 146.5 -6.22 -0.08 161.0 23.446540880503 0.333725874376275 0.2265 0.6144 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P17 mock treatment 275.0 79.8 0.79 175.0 22.3 0.28 174.0 36.446540880503 0.51876111641913 0.9134 0.9305 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P18 mock treatment 117.0 -78.2 -0.77 152.0 -0.722 -0.01 174.0 36.446540880503 0.51876111641913 -0.1499 -0.1616 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P19 mock treatment 194.0 -1.17 -0.01 156.5 3.78 0.05 154.5 16.946540880503 0.241208253354847 0.1598 0.6494 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P20 mock treatment 213.0 17.8 0.18 143.0 -9.72 -0.12 124.5 -13.053459119497 -0.185796151359434 -0.0759 -0.2683 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P21 mock treatment 216.0 20.8 0.21 156.0 3.28 0.04 109.0 -28.553459119497 -0.406415093795146 -0.0927 -0.2029 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P22 mock treatment 172.0 -23.2 -0.23 127.0 -25.7 -0.32 108.0 -29.553459119497 -0.420648573952289 -0.5595 -0.9716 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P23 mock treatment 211.0 15.8 0.16 195.5 42.8 0.53 154.5 16.946540880503 0.241208253354847 0.5368 0.8869 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2104 P24 compound treatment 138.0 -57.2 -0.56 163.0 10.3 0.13 100.0 -37.553459119497 -0.53451641520943 -0.5596 -0.7114 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A01 compound treatment 115.0 -103.0 -1.01 136.0 -68.5 -0.85 158.5 -55.383647798742 -0.788302051973575 -1.5326 -0.9944 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A02 mock treatment 215.0 -2.91 -0.03 313.0 108.0 1.35 208.0 -5.883647798742 -0.0837447841950107 0.7152 0.5282 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A03 mock treatment 179.0 -38.9 -0.38 206.0 1.49 0.02 247.0 33.116352201258 0.471360941933555 0.0617 0.1016 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A04 mock treatment 200.5 -17.4 -0.17 245.0 40.5 0.5 239.0 25.116352201258 0.357493100676413 0.3986 0.6214 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A05 mock treatment 220.0 2.09 0.02 153.0 -51.5 -0.64 207.0 -6.883647798742 -0.0979782643521534 -0.4151 -0.6393 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A06 mock treatment 248.0 30.1 0.3 212.0 7.49 0.09 208.5 -5.383647798742 -0.0766280441164393 0.1806 0.5648 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A07 mock treatment 210.5 -7.41 -0.07 202.0 -2.51 -0.03 211.0 -2.883647798742 -0.0410443437235826 -0.0839 -0.9384 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A08 mock treatment 271.0 53.1 0.52 203.0 -1.51 -0.02 146.0 -67.883647798742 -0.966220553937858 -0.267 -0.243 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A09 mock treatment 265.0 47.1 0.46 199.0 -5.51 -0.07 203.0 -10.883647798742 -0.154912184980724 0.1385 0.2808 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A10 mock treatment 143.5 -74.4 -0.73 141.0 -63.5 -0.79 235.0 21.116352201258 0.300559180047842 -0.706 -0.6309 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A11 mock treatment 232.0 14.1 0.14 200.0 -4.51 -0.06 202.0 -11.883647798742 -0.169145665137867 -0.05 -0.2215 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A12 mock treatment 258.0 40.1 0.39 146.5 -58.0 -0.72 175.0 -38.883647798742 -0.55344962938072 -0.5088 -0.513 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A13 mock treatment 210.0 -7.91 -0.08 215.5 11.0 0.14 143.0 -70.883647798742 -1.00892099440929 -0.5484 -0.5371 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A14 mock treatment 260.0 42.1 0.41 136.0 -68.5 -0.85 155.5 -58.383647798742 -0.831002492445003 -0.7332 -0.5815 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A15 mock treatment 223.0 5.09 0.05 360.0 155.0 1.94 173.0 -40.883647798742 -0.581916589695005 0.8111 0.401 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A16 mock treatment 243.0 25.1 0.25 163.0 -41.5 -0.52 207.0 -6.883647798742 -0.0979782643521534 -0.2125 -0.3656 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A17 mock treatment 227.0 9.09 0.09 140.5 -64.0 -0.8 191.0 -22.883647798742 -0.325713946866437 -0.5967 -0.6892 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A18 mock treatment 223.0 5.09 0.05 130.5 -74.0 -0.92 187.0 -26.883647798742 -0.382647867495007 -0.7242 -0.7247 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A19 mock treatment 129.0 -88.9 -0.88 126.0 -78.5 -0.98 218.5 4.616352201258 0.0657067574549877 -1.0319 -0.7854 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A20 mock treatment 160.5 -57.4 -0.57 133.5 -71.0 -0.88 249.0 35.116352201258 0.49982790224784 -0.5483 -0.4717 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A21 mock treatment 206.5 -11.4 -0.11 156.0 -48.5 -0.6 143.0 -70.883647798742 -1.00892099440929 -0.9962 -0.8433 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A22 mock treatment 144.5 -73.4 -0.72 145.5 -59.0 -0.73 257.0 43.116352201258 0.613695743504982 -0.4872 -0.4061 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A23 compound treatment 139.5 -78.4 -0.77 112.0 -92.5 -1.15 179.5 -34.383647798742 -0.489398968673578 -1.3934 -0.9475 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 A24 mock treatment 163.0 -54.9 -0.54 178.0 -26.5 -0.33 171.0 -42.883647798742 -0.610383550009291 -0.8551 -0.9721 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B01 mock treatment 164.0 -53.9 -0.53 131.0 -73.5 -0.92 193.5 -20.383647798742 -0.29013024647358 -1.0025 -0.9136 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B02 compound treatment 64.0 -154.0 -1.51 155.5 -49.0 -0.61 147.5 -66.383647798742 -0.944870333702144 -1.7726 -0.9394 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B03 compound treatment 117.0 -101.0 -0.99 126.5 -78.0 -0.97 178.5 -35.383647798742 -0.50363244883072 -1.4252 -0.9643 577 HSCI1_000201 CN1C(=O)C(=C(C1=O)c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B04 compound treatment 240.0 22.1 0.22 216.0 11.5 0.14 196.5 -17.383647798742 -0.247429806002152 0.0653 0.1818 614 HSCI1_000202 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c65 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B05 compound treatment 244.0 26.1 0.26 188.0 -16.5 -0.21 227.0 13.116352201258 0.186691338790701 0.1373 0.3631 907102 HSCI1_000203 NCCCCCCNS(=O)(=O)c1cccc2ccccc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B06 compound treatment 252.0 34.1 0.34 223.5 19.0 0.24 227.0 13.116352201258 0.186691338790701 0.4381 0.9714 1012954 HSCI1_000204 OC(Cc1ccncc1)C(Cl)(Cl)Cl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B07 compound treatment 192.0 -25.9 -0.26 215.0 10.5 0.13 246.0 32.116352201258 0.457127461776412 0.1921 0.3561 3176210 HSCI1_000205 CCCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B08 compound treatment 345.0 127.0 1.25 364.5 160.0 1.99 351.0 137.116352201258 1.9516428782764 2.9995 0.9812 321 HSCI1_000206 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B09 compound treatment 211.5 -6.41 -0.06 108.0 -96.5 -1.2 514.0 300.116352201258 4.27170014389066 1.7359 0.3911 3176211 HSCI1_000207 C[C@@H](O)[C@]1(C)CC[C@@H](O1)[C@]2(C)CC[C@@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C/C[C@@H](C)C[C@@H](C)/C(=C/C(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(=O)O)/O)O2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B10 compound treatment 354.5 137.0 1.34 325.0 120.0 1.5 209.5 -4.383647798742 -0.0623945639592966 1.6066 0.797 3103895 HSCI1_000208 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B11 mock treatment 120.5 -97.4 -0.96 113.0 -91.5 -1.14 127.5 -86.383647798742 -1.229539936845 -1.9215 -0.9949 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B12 mock treatment 202.0 -15.9 -0.16 244.5 40.0 0.5 210.5 -3.383647798742 -0.0481610838021539 0.1693 0.3229 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B13 mock treatment 108.5 -109.0 -1.08 140.0 -64.5 -0.8 18.5 -195.383647798742 -2.78098927397355 -2.6912 -0.8714 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B14 mock treatment 221.0 3.09 0.03 151.0 -53.5 -0.67 244.0 30.116352201258 0.428660501462127 -0.1197 -0.151 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B15 compound treatment 282.0 64.1 0.63 190.5 -14.0 -0.17 346.0 132.116352201258 1.88047547749068 1.3492 0.6776 1940 HSCI1_000209 NSC(=S)N1CCCC1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B16 compound treatment 238.0 20.1 0.2 169.0 -35.5 -0.44 214.5 0.616352201257996 0.00877283682641691 -0.1361 -0.2809 1000071 HSCI1_000210 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B17 compound treatment 237.0 19.1 0.19 142.0 -62.5 -0.78 182.0 -31.883647798742 -0.453815268280721 -0.603 -0.6551 3176212 HSCI1_000211 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)[C@@H]3O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B18 compound treatment 144.0 -73.9 -0.73 150.0 -54.5 -0.68 171.5 -42.383647798742 -0.603266809930719 -1.1603 -0.9971 831767 HSCI1_000212 NCCCNCCCCNCCCN 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B19 compound treatment 213.0 -4.91 -0.05 137.5 -67.0 -0.83 221.0 7.116352201258 0.101290457847844 -0.4513 -0.5359 3054778 HSCI1_000213 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B20 compound treatment 137.5 -80.4 -0.79 118.0 -86.5 -1.08 220.5 6.616352201258 0.0941737177692731 -1.0247 -0.7645 2293 HSCI1_000214 CSC(=N)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B21 compound treatment 212.0 -5.91 -0.06 106.5 -98.0 -1.22 229.0 15.116352201258 0.215158299104986 -0.6141 -0.4949 1001920 HSCI1_000215 CNC[C@H](O)c1ccc(O)c(O)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B22 compound treatment 351.0 133.0 1.31 195.5 -9.01 -0.11 298.0 84.116352201258 1.19726842994783 1.3828 0.7776 3054779 HSCI1_000216 CN/C(=N\C)/NCCC[C@H](N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B23 mock treatment 150.0 -67.9 -0.67 148.0 -56.5 -0.7 159.0 -54.883647798742 -0.781185311895003 -1.2433 -0.9979 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 B24 compound treatment 85.0 -133.0 -1.31 126.0 -78.5 -0.98 112.0 -101.883647798742 -1.45015887928071 -2.1571 -0.9876 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C01 compound treatment 86.0 -132.0 -1.3 156.0 -48.5 -0.6 155.0 -58.883647798742 -0.838119232523574 -1.5823 -0.9536 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C02 mock treatment 260.0 42.1 0.41 265.0 60.5 0.75 248.5 34.616352201258 0.492711162169269 0.9586 0.9674 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C03 compound treatment 118.0 -99.9 -0.98 150.0 -54.5 -0.68 240.0 26.116352201258 0.371726580833556 -0.7451 -0.5954 2022 HSCI1_000217 CC1(C)C(C=C(Br)Br)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C04 compound treatment 274.0 56.1 0.55 249.0 44.5 0.55 251.0 37.116352201258 0.528294862562126 0.9437 0.9998 3176214 HSCI1_000218 COc1ccc2c(cc(C)c3nnc(SCC(=O)Nc4cccc(c4)C(=O)C)n32)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C05 compound treatment 152.5 -65.4 -0.64 122.0 -82.5 -1.03 137.0 -76.883647798742 -1.09432187535214 -1.5968 -0.9776 3054780 HSCI1_000219 CCCCc1c([nH]c2nccnc12)c3ccc(O)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C06 compound treatment 236.0 18.1 0.18 245.0 40.5 0.5 246.0 32.116352201258 0.457127461776412 0.6579 0.9351 3054781 HSCI1_000220 NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+](=O)[O-])cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C07 compound treatment 153.5 -64.4 -0.63 147.0 -57.5 -0.72 168.0 -45.883647798742 -0.653083990480719 -1.1566 -0.9986 360 HSCI1_000221 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C08 compound treatment 303.0 85.1 0.84 143.5 -61.0 -0.76 255.0 41.116352201258 0.585228783190696 0.3827 0.3006 2260 HSCI1_000222 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(CO)c8c1c2c(c34)c(c65)c78 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C09 compound treatment 236.0 18.1 0.18 235.0 30.5 0.38 252.0 38.116352201258 0.542528342719268 0.6353 0.9264 3054782 HSCI1_000223 O=c1cc(oc2c1ccc3ccccc32)N4CCOCC4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C10 compound treatment 240.0 22.1 0.22 193.5 -11.0 -0.14 201.0 -12.883647798742 -0.18337914529501 -0.0595 -0.1885 3176215 HSCI1_000224 C1CCC(CC1)n2cnc3c(Nc4ccc(cc4)N5CCOCC5)nc(Oc6cccc7ccccc67)nc23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C11 mock treatment 292.0 74.1 0.73 249.0 44.5 0.55 265.0 51.116352201258 0.727563584762123 1.161 0.9926 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C12 mock treatment 81.5 -136.0 -1.34 126.0 -78.5 -0.98 129.0 -84.883647798742 -1.20818971660928 -2.0373 -0.9919 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C13 mock treatment 260.0 42.1 0.41 174.0 -30.5 -0.38 174.0 -39.883647798742 -0.567683109537863 -0.3079 -0.3855 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C14 mock treatment 185.0 -32.9 -0.32 154.0 -50.5 -0.63 138.5 -75.383647798742 -1.07297165511643 -1.1697 -0.9101 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C15 mock treatment 225.0 7.09 0.07 229.5 25.0 0.31 212.0 -1.883647798742 -0.0268108635664398 0.2045 0.6388 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C16 mock treatment 153.0 -64.9 -0.64 99.0 -106.0 -1.31 185.0 -28.883647798742 -0.411114827809293 -1.3649 -0.8992 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C17 compound treatment 267.0 49.1 0.48 257.0 52.5 0.65 216.0 2.116352201258 0.030123057062131 0.6738 0.8283 3176216 HSCI1_000225 CCCCCCCCCCCCCCCCC(=C)OOCC(COP(=O)(ON)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(=O)(O)ON)[C@H](OP(=O)(O)ON)[C@H]1O)OOC(=C)CC/C=C/C/C=C/C\C=C\C\C=C\CCCCC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C18 compound treatment 271.0 53.1 0.52 173.5 -31.0 -0.39 277.5 63.616352201258 0.905482086726407 0.6015 0.5397 907140 HSCI1_000226 NCCCCNS(=O)(=O)c1ccc2ccccc2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C19 compound treatment 231.5 13.6 0.13 225.0 20.5 0.26 214.5 0.616352201257996 0.00877283682641691 0.2296 0.7966 3054783 HSCI1_000227 Nc1nc2n(cnc2c(=O)[nH]1)C3OC(COP(=O)(O)OP(=S)(O)O)[C@H](O)[C@@H]3O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C20 compound treatment 246.0 28.1 0.28 428.0 223.0 2.78 377.5 163.616352201258 2.32883010244068 3.1113 0.8548 2081802 HSCI1_000228 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C21 compound treatment 128.5 -89.4 -0.88 178.0 -26.5 -0.33 237.5 23.616352201258 0.336142880440699 -0.5047 -0.5055 3176218 HSCI1_000229 Nc1nc2n(C3OC4COP(O)(O)OC4C3O)c(Br)nc2c(=O)[nH]1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C22 compound treatment 352.0 134.0 1.32 167.0 -37.5 -0.47 303.5 89.616352201258 1.27555257081212 1.2287 0.6488 3054784 HSCI1_000230 Nc1nc(Cl)nc2n(cnc12)C3C[C@@H](O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C23 compound treatment 214.0 -3.91 -0.04 140.0 -64.5 -0.8 249.5 35.616352201258 0.506944642326412 -0.1934 -0.2034 1338 HSCI1_000231 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 C24 mock treatment 185.0 -32.9 -0.32 118.0 -86.5 -1.08 212.5 -1.383647798742 -0.0196941234878685 -0.8205 -0.7291 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D01 mock treatment 118.0 -99.9 -0.98 252.0 47.5 0.59 246.0 32.116352201258 0.457127461776412 0.0376 0.0305 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D02 compound treatment 167.5 -50.4 -0.5 106.0 -98.5 -1.23 118.5 -95.383647798742 -1.35764125825928 -1.7787 -0.9381 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D03 compound treatment 470.0 252.0 2.48 553.0 348.0 4.34 329.0 115.116352201258 1.63850631481926 4.8845 0.9284 3176219 HSCI1_000232 O/N=C/1\C(=C/2\C(=O)Nc3cc(Br)ccc23)\Nc4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D04 compound treatment 308.0 90.1 0.89 277.0 72.5 0.9 258.0 44.116352201258 0.627929223662125 1.3958 0.988 3054785 HSCI1_000233 O=C1NC(=O)c2c1ccc(Nc3ccccc3)c2Nc4ccccc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D05 compound treatment 225.5 7.59 0.07 236.5 32.0 0.4 209.5 -4.383647798742 -0.0623945639592966 0.2371 0.5781 1277018 HSCI1_000234 COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D06 compound treatment 255.5 37.6 0.37 272.0 67.5 0.84 234.0 20.116352201258 0.2863256998907 0.8642 0.8984 1919 HSCI1_000235 CCCCCc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D07 compound treatment 216.0 -1.91 -0.02 159.5 -45.0 -0.56 209.0 -4.883647798742 -0.069511304037868 -0.3746 -0.6629 3176221 HSCI1_000236 C1C[C@H](N/C/2=N/CCCCCCCCCCC2)[C@@H](C1)c3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D08 compound treatment 147.5 -70.4 -0.69 140.0 -64.5 -0.8 146.0 -67.883647798742 -0.966220553937858 -1.4219 -0.9908 3054786 HSCI1_000237 OCC1OC([C@@H](O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D09 compound treatment 263.5 45.6 0.45 255.0 50.5 0.63 203.0 -10.883647798742 -0.154912184980724 0.5327 0.6761 3176222 HSCI1_000238 COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D10 compound treatment 263.0 45.1 0.44 178.0 -26.5 -0.33 185.0 -28.883647798742 -0.411114827809293 -0.1717 -0.2492 407 HSCI1_000239 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D11 mock treatment 243.0 25.1 0.25 207.0 2.49 0.03 189.0 -24.883647798742 -0.354180907180722 -0.044 -0.1016 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D12 mock treatment 261.5 43.6 0.43 239.5 35.0 0.44 274.0 60.116352201258 0.855664906176408 0.9933 0.9445 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D13 mock treatment 258.0 40.1 0.39 242.0 37.5 0.47 256.0 42.116352201258 0.599462263347839 0.8435 0.9852 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D14 mock treatment 291.0 73.1 0.72 257.0 52.5 0.65 284.0 70.116352201258 0.997999707747835 1.369 0.9826 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D15 mock treatment 257.0 39.1 0.38 160.0 -44.5 -0.55 237.0 23.116352201258 0.329026140362128 0.092 0.1226 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D16 mock treatment 295.0 77.1 0.76 271.0 66.5 0.83 260.0 46.116352201258 0.65639618397641 1.2952 0.9956 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D17 compound treatment 264.0 46.1 0.45 232.0 27.5 0.34 212.0 -1.883647798742 -0.0268108635664398 0.4441 0.7805 3054787 HSCI1_000240 N/N=C(/N)\NO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D18 compound treatment 271.0 53.1 0.52 157.0 -47.5 -0.59 204.0 -9.883647798742 -0.140678704823581 -0.1211 -0.1511 907294 HSCI1_000241 CN(C)C(=N)NCCC[C@H](N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D19 compound treatment 268.0 50.1 0.49 170.0 -34.5 -0.43 199.0 -14.883647798742 -0.211846105609295 -0.0858 -0.1248 3176223 HSCI1_000242 CSC(=N)NCCC[C@H](N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D20 compound treatment 302.0 84.1 0.83 138.0 -66.5 -0.83 246.0 32.116352201258 0.457127461776412 0.2635 0.2097 3054789 HSCI1_000243 CNC(=N)NCCC[C@@H](N)C=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D21 compound treatment 295.0 77.1 0.76 182.0 -22.5 -0.28 323.5 109.616352201258 1.56022217395497 1.177 0.6697 3176224 HSCI1_000244 OP(=O)(O)C(Cl)(Cl)P(=O)(O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D22 compound treatment 270.0 52.1 0.51 160.0 -44.5 -0.55 258.0 44.116352201258 0.627929223662125 0.3385 0.3447 3176225 HSCI1_000245 CNC(=N)NCCC[C@H](N)C=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D23 compound treatment 194.0 -23.9 -0.24 149.0 -55.5 -0.69 263.0 49.116352201258 0.699096624447838 -0.1314 -0.13 2215 HSCI1_000246 CCCNC(=N)NCCCC(N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 D24 compound treatment 111.0 -107.0 -1.05 111.0 -93.5 -1.16 125.5 -88.383647798742 -1.25800689715928 -2.0063 -0.9974 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E01 compound treatment 158.0 -59.9 -0.59 77.5 -127.0 -1.58 117.0 -96.883647798742 -1.378991478495 -2.0499 -0.9404 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E02 mock treatment 231.0 13.1 0.13 225.0 20.5 0.26 188.0 -25.883647798742 -0.368414387337865 0.009 0.0194 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E03 mock treatment 107.0 -111.0 -1.09 129.0 -75.5 -0.94 125.5 -88.383647798742 -1.25800689715928 -1.8996 -0.9931 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E04 mock treatment 173.0 -44.9 -0.44 141.5 -63.0 -0.78 234.0 20.116352201258 0.2863256998907 -0.543 -0.5745 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E05 compound treatment 120.5 -97.4 -0.96 110.0 -94.5 -1.18 158.0 -55.883647798742 -0.795418792052146 -1.6924 -0.9874 3176226 HSCI1_000247 CCCCc1c([nH]c2nccnc12)c3ccc(OC)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E06 compound treatment 163.0 -54.9 -0.54 171.0 -33.5 -0.42 293.0 79.116352201258 1.12610102916212 0.0971 0.0738 2371 HSCI1_000248 CCCCCCCCNC(=O)C(Cc1ccc(OCc2ccncc2)cc1)NC(=O)C3CCC(CN)CC3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E07 compound treatment 349.0 131.0 1.29 264.0 59.5 0.74 250.5 36.616352201258 0.521178122483554 1.4737 0.9347 1989 HSCI1_000249 Clc1[nH]c2ccccc2c1/C=C\3/C(=O)Nc4ccccc34 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E08 compound treatment 413.0 195.0 1.92 284.0 79.5 0.99 447.0 233.116352201258 3.3180569733621 3.596 0.9082 1416171 HSCI1_000250 OC(CN1CCNCC1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E09 mock treatment 228.0 10.1 0.1 251.0 46.5 0.58 196.0 -17.883647798742 -0.254546546080723 0.2447 0.3821 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E10 mock treatment 203.0 -14.9 -0.15 288.0 83.5 1.04 227.0 13.116352201258 0.186691338790701 0.6234 0.5844 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E11 compound treatment 143.0 -74.9 -0.74 155.5 -49.0 -0.61 170.5 -43.383647798742 -0.617500290087862 -1.1346 -0.9961 663 HSCI1_000251 Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E12 compound treatment 162.0 -55.9 -0.55 428.5 224.0 2.79 354.5 140.616352201258 2.0014600588264 2.4485 0.7041 1000089 HSCI1_000252 COC1C(C)OC(OC2CC(C)(O)C(C(=O)OC)c3cc4C(=O)c5c6OC7OC(C)(C(O)C(C7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)C(OC)C1(C)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E13 compound treatment 210.5 -7.41 -0.07 158.0 -46.5 -0.58 169.0 -44.883647798742 -0.638850510323576 -0.7454 -0.8613 3054791 HSCI1_000253 Nc1nc2n(cnc2c(=O)[nH]1)C3OC4COP(O)(O)OC4C3O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E14 compound treatment 212.0 -5.91 -0.06 184.0 -20.5 -0.26 207.5 -6.383647798742 -0.090861524273582 -0.2335 -0.8423 3176276 HSCI1_000254 NCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-])C(=O)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E15 mock treatment 184.0 -33.9 -0.33 150.5 -54.0 -0.67 160.0 -53.883647798742 -0.76695183173786 -1.0239 -0.9539 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E16 mock treatment 198.0 -19.9 -0.2 175.0 -29.5 -0.37 224.5 10.616352201258 0.151107638397844 -0.2381 -0.5374 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E17 mock treatment 225.0 7.09 0.07 152.0 -52.5 -0.65 240.0 26.116352201258 0.371726580833556 -0.1227 -0.1624 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E18 mock treatment 247.0 29.1 0.29 189.0 -15.5 -0.19 217.5 3.616352201258 0.051473277297845 0.0835 0.2392 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E19 compound treatment 215.0 -2.91 -0.03 182.0 -22.5 -0.28 256.0 42.116352201258 0.599462263347839 0.1677 0.2532 1000095 HSCI1_000255 CC(O)C(O)[C@H]1CNc2nc(N)[nH]c(=O)c2N1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E20 compound treatment 175.0 -42.9 -0.42 205.5 0.994 0.01 267.0 53.116352201258 0.756030545076409 0.1998 0.2306 3054834 HSCI1_000256 NCCNC[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E21 compound treatment 165.5 -52.4 -0.52 140.0 -64.5 -0.8 204.0 -9.883647798742 -0.140678704823581 -0.8429 -0.8734 423 HSCI1_000257 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E22 compound treatment 230.0 12.1 0.12 130.0 -74.5 -0.93 274.5 60.616352201258 0.862781646254979 0.031 0.0244 2114444 HSCI1_000258 O=c1n(CCN2CCCCC2)c(=O)c3ccc4c5ccc6c(=O)n(CCN7CCCCC7)c(=O)c8ccc(c9ccc1c3c94)c5c86 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E23 compound treatment 121.0 -96.9 -0.95 123.0 -81.5 -1.02 249.0 35.116352201258 0.49982790224784 -0.8483 -0.5732 832002 HSCI1_000259 CC(=N)NCCC[C@H](N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 E24 mock treatment 330.0 112.0 1.1 151.0 -53.5 -0.67 195.5 -18.383647798742 -0.261663286159294 0.1011 0.0769 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F01 mock treatment 169.0 -48.9 -0.48 217.5 13.0 0.16 222.0 8.116352201258 0.115523938004987 -0.1178 -0.2262 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F02 compound treatment 161.0 -56.9 -0.56 151.0 -53.5 -0.67 133.5 -80.383647798742 -1.14413905590214 -1.3688 -0.952 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F03 mock treatment 184.0 -33.9 -0.33 209.0 4.49 0.06 231.0 17.116352201258 0.243625259419272 -0.0198 -0.0474 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F04 mock treatment 164.0 -53.9 -0.53 159.0 -45.5 -0.57 130.0 -83.883647798742 -1.19395623645214 -1.3229 -0.9289 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F05 compound treatment 198.0 -19.9 -0.2 211.0 6.49 0.08 410.5 196.616352201258 2.79853494762639 1.5493 0.552 3176278 HSCI1_000260 CC(=O)O/N=C/1\C(=C/2\C(=O)Nc3cc(Br)ccc23)\Nc4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F06 compound treatment 256.0 38.1 0.37 258.5 54.0 0.67 239.0 25.116352201258 0.357493100676413 0.8111 0.9555 1505 HSCI1_000261 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F07 compound treatment 437.5 220.0 2.16 489.0 284.0 3.54 284.5 70.616352201258 1.00511644782641 3.8739 0.9071 3054836 HSCI1_000262 COc1ccc(CNc2nc(nc3n(cnc23)C(C)C)N(CCO)CCO)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F08 compound treatment 166.5 -51.4 -0.51 221.0 16.5 0.21 165.5 -48.383647798742 -0.688667690873576 -0.5712 -0.6498 1980 HSCI1_000263 CC1(C2CCC(O2)C1(C)C(=O)O)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F09 mock treatment 250.0 32.1 0.32 190.5 -14.0 -0.17 199.5 -14.383647798742 -0.204729365530724 -0.0366 -0.0882 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F10 mock treatment 295.0 77.1 0.76 274.5 70.0 0.87 255.0 41.116352201258 0.585228783190696 1.2793 0.9875 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F11 compound treatment 217.5 -0.415 0.0 214.5 9.99 0.12 200.0 -13.883647798742 -0.197612625452152 -0.0446 -0.1909 832084 HSCI1_000264 NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c4nc[nH]c4n2)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F12 compound treatment 165.5 -52.4 -0.52 232.5 28.0 0.35 150.0 -63.883647798742 -0.909286633309288 -0.6215 -0.564 445 HSCI1_000265 NC(=O)c1cccc(N)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F13 compound treatment 246.5 28.6 0.28 217.0 12.5 0.16 226.0 12.116352201258 0.172457858633558 0.3519 0.9644 2194 HSCI1_000266 OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(c3)[N+](=O)[O-])ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F14 compound treatment 223.0 5.09 0.05 180.5 -24.0 -0.3 231.0 17.116352201258 0.243625259419272 -0.0031 -0.0079 2025 HSCI1_000267 NCCCC(N)(C(F)F)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F15 mock treatment 187.0 -30.9 -0.3 161.0 -43.5 -0.54 187.5 -26.383647798742 -0.375531127416436 -0.7053 -0.9714 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F16 mock treatment 183.0 -34.9 -0.34 228.0 23.5 0.29 246.5 32.616352201258 0.464244201854983 0.2386 0.3684 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F17 mock treatment 254.0 36.1 0.36 202.0 -2.51 -0.03 222.0 8.116352201258 0.115523938004987 0.2537 0.677 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F18 mock treatment 233.5 15.6 0.15 187.0 -17.5 -0.22 237.0 23.116352201258 0.329026140362128 0.1526 0.3605 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F19 compound treatment 254.0 36.1 0.36 180.0 -24.5 -0.31 240.0 26.116352201258 0.371726580833556 0.2435 0.4072 2259 HSCI1_000268 CN1CCc2cc3OCOc3cc2C(=O)Cc4ccc5OCOc5c4C1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F20 compound treatment 265.0 47.1 0.46 117.0 -87.5 -1.09 206.0 -7.883647798742 -0.112211744509296 -0.4264 -0.3585 2674 HSCI1_000269 N[C@@H](CCC(=O)O)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F21 compound treatment 289.0 71.1 0.7 176.0 -28.5 -0.36 131.0 -82.883647798742 -1.179722756295 -0.4821 -0.3403 3176279 HSCI1_000270 CC[C@]1(O)C[C@H]2CN(C1)CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)[C@@H]7[C@@]86CCN9CC=C[C@@](CC)([C@H]98)[C@@H](OC(=O)C)[C@]7(O)C(=O)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F22 compound treatment 129.5 -88.4 -0.87 117.0 -87.5 -1.09 199.0 -14.883647798742 -0.211846105609295 -1.254 -0.8889 2129 HSCI1_000271 OCC(O)C1OC(=O)C(=C1O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F23 compound treatment 258.0 40.1 0.39 292.5 88.0 1.1 465.0 251.116352201258 3.57425961619066 2.9241 0.7778 1000078 HSCI1_000272 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 F24 compound treatment 108.0 -110.0 -1.08 85.0 -120.0 -1.49 171.0 -42.883647798742 -0.610383550009291 -1.8364 -0.9472 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G01 compound treatment 69.0 -149.0 -1.47 103.5 -101.0 -1.26 154.0 -59.883647798742 -0.852352712680717 -2.0647 -0.9779 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G02 compound treatment 238.0 20.1 0.2 257.0 52.5 0.65 271.5 57.616352201258 0.820081205783551 0.9651 0.9043 25 HSCI1_000273 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G03 mock treatment 152.5 -65.4 -0.64 164.0 -40.5 -0.5 129.5 -84.383647798742 -1.20107297653071 -1.3565 -0.9335 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G04 mock treatment 287.0 69.1 0.68 223.0 18.5 0.23 251.0 37.116352201258 0.528294862562126 0.8306 0.9318 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G05 mock treatment 233.0 15.1 0.15 156.5 -48.0 -0.6 287.0 73.116352201258 1.04070014821926 0.3414 0.2823 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G06 mock treatment 249.0 31.1 0.31 219.0 14.5 0.18 251.0 37.116352201258 0.528294862562126 0.5859 0.9203 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G07 compound treatment 220.0 2.09 0.02 239.0 34.5 0.43 243.0 29.116352201258 0.414427021304984 0.4992 0.8357 3054838 HSCI1_000274 CC(C)(c1ccc(NS(=O)(=O)C(F)(F)F)cc1)c2ccc(cc2)C(C)(C)c3cccc(NS(=O)(=O)C(F)(F)F)c3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G08 compound treatment 274.0 56.1 0.55 227.5 23.0 0.29 199.0 -14.883647798742 -0.211846105609295 0.3618 0.5506 546 HSCI1_000275 Cc1ncc2ccccc2c1C#N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G09 compound treatment 226.5 8.59 0.08 241.0 36.5 0.45 205.0 -8.883647798742 -0.126445224666439 0.2382 0.497 1947905 HSCI1_000276 Clc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1Cl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G10 compound treatment 227.0 9.09 0.09 223.5 19.0 0.24 170.5 -43.383647798742 -0.617500290087862 -0.1683 -0.2522 636 HSCI1_000277 C/C(=C(\C#N)/C(=O)Nc1cccc(F)c1)/O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G11 compound treatment 215.0 -2.91 -0.03 280.0 75.5 0.94 177.0 -36.883647798742 -0.524982669066434 0.2232 0.2072 3176281 HSCI1_000278 COc1ccc(CNC(=O)Nc2ncc(s2)[N+](=O)[O-])cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G12 compound treatment 229.5 11.6 0.11 214.5 9.99 0.12 191.0 -22.883647798742 -0.325713946866437 -0.0504 -0.1372 3054840 HSCI1_000279 CC1OC(C[C@H]1O)n2cnc3c(N)ncnc23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G13 compound treatment 324.5 107.0 1.05 249.0 44.5 0.55 255.0 41.116352201258 0.585228783190696 1.2635 0.9551 2319 HSCI1_000280 CN(C)CC1Cc2ccccc2C1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G14 compound treatment 327.0 109.0 1.07 253.0 48.5 0.6 253.0 39.116352201258 0.556761822876411 1.2901 0.9543 3176282 HSCI1_000281 N[C@@H](CCN/C(=N/O)/N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G15 compound treatment 154.0 -63.9 -0.63 128.0 -76.5 -0.95 120.0 -93.883647798742 -1.33629103802357 -1.6849 -0.9586 2145 HSCI1_000282 NC(=N)NCCS 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G16 compound treatment 201.0 -16.9 -0.17 223.0 18.5 0.23 209.0 -4.883647798742 -0.069511304037868 -0.0033 -0.0112 3583 HSCI1_000283 Cn1cc(NC(=O)c2cc(NC(=O)CNC(=N)N)cn2C)cc1C(=O)NCCC(=N)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G17 mock treatment 352.0 134.0 1.32 198.0 -6.51 -0.08 309.0 95.116352201258 1.3538367116764 1.4968 0.791 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G18 mock treatment 253.0 35.1 0.35 212.0 7.49 0.09 257.0 43.116352201258 0.613695743504982 0.6076 0.8553 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G19 mock treatment 229.0 11.1 0.11 256.0 51.5 0.64 263.5 49.616352201258 0.706213364526409 0.841 0.8759 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G20 mock treatment 258.5 40.6 0.4 221.0 16.5 0.21 267.0 53.116352201258 0.756030545076409 0.7857 0.8935 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G21 compound treatment 231.5 13.6 0.13 153.0 -51.5 -0.64 228.0 14.116352201258 0.200924818947843 -0.1772 -0.2585 1030173 HSCI1_000284 NC(=N)NO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G22 compound treatment 168.5 -49.4 -0.49 313.5 109.0 1.36 228.5 14.616352201258 0.208041559026415 0.623 0.4276 3176283 HSCI1_000285 COc1cc(ccc1[n+]2nc(nn2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)c5ccc(c(OC)c5)[n+]6nc(nn6c7ccc(cc7)[N+](=O)[O-])c8ccccc8 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G23 compound treatment 194.0 -23.9 -0.24 130.5 -74.0 -0.92 229.0 15.116352201258 0.215158299104986 -0.5438 -0.5576 469 HSCI1_000286 CCCC(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 G24 mock treatment 172.5 -45.4 -0.45 158.0 -46.5 -0.58 237.0 23.116352201258 0.329026140362128 -0.4025 -0.5018 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H01 mock treatment 243.5 25.6 0.25 151.0 -53.5 -0.67 235.5 21.616352201258 0.307675920126414 -0.0617 -0.0795 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H02 compound treatment 125.0 -92.9 -0.91 138.0 -66.5 -0.83 234.0 20.116352201258 0.2863256998907 -0.8409 -0.6639 1594 HSCI1_000287 N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H03 mock treatment 228.5 10.6 0.1 241.0 36.5 0.45 222.0 8.116352201258 0.115523938004987 0.3893 0.8103 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H04 mock treatment 105.0 -113.0 -1.11 158.0 -46.5 -0.58 140.0 -73.883647798742 -1.05162143488071 -1.5833 -0.9677 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H05 mock treatment 158.0 -59.9 -0.59 254.0 49.5 0.62 207.0 -6.883647798742 -0.0979782643521534 -0.0412 -0.0479 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H06 mock treatment 240.0 22.1 0.22 247.0 42.5 0.53 222.5 8.616352201258 0.122640678083559 0.5019 0.8577 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H07 compound treatment 170.0 -47.9 -0.47 171.0 -33.5 -0.42 164.5 -49.383647798742 -0.702901171030718 -0.9191 -0.9738 3054842 HSCI1_000288 CSc1nc(c([nH]1)c2ccnc(NC(C)c3ccccc3)c2)c4ccc(F)cc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H08 compound treatment 219.0 1.09 0.01 192.0 -12.5 -0.16 125.0 -88.883647798742 -1.26512363723786 -0.8142 -0.6387 1961 HSCI1_000289 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H09 compound treatment 121.0 -96.9 -0.95 145.0 -59.5 -0.74 87.0 -126.883647798742 -1.80599588320928 -2.0213 -0.9303 572 HSCI1_000290 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H10 compound treatment 270.0 52.1 0.51 261.5 57.0 0.71 165.5 -48.383647798742 -0.688667690873576 0.3082 0.2767 1907755 HSCI1_000291 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H11 compound treatment 178.0 -39.9 -0.39 136.0 -68.5 -0.85 137.0 -76.883647798742 -1.09432187535214 -1.3513 -0.9369 574 HSCI1_000292 NCCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H12 compound treatment 224.0 6.09 0.06 220.0 15.5 0.19 176.0 -37.883647798742 -0.539216149223577 -0.1653 -0.2871 3176284 HSCI1_000293 COc1cc2C3CC[C@]4(C)[C@@H](O)CCC4C3CCc2cc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H13 compound treatment 231.5 13.6 0.13 241.5 37.0 0.46 213.0 -0.883647798742004 -0.0125773834092971 0.336 0.7 2195 HSCI1_000294 OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c3)ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H14 compound treatment 219.0 1.09 0.01 193.5 -11.0 -0.14 194.0 -19.883647798742 -0.283013506395009 -0.2364 -0.7512 1714 HSCI1_000295 CN(C)C(=N)NC(=N)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H15 compound treatment 237.0 19.1 0.19 207.0 2.49 0.03 171.0 -42.883647798742 -0.610383550009291 -0.226 -0.3535 2197 HSCI1_000296 OS(=O)(=O)c1ccc(NC(=O)c2cc(NC(=O)Nc3cc(cc(c3)C(=O)Nc4ccc(cc4S(=O)(=O)O)S(=O)(=O)O)C(=O)Nc5ccc(cc5S(=O)(=O)O)S(=O)(=O)O)cc(c2)C(=O)Nc6ccc(cc6S(=O)(=O)O)S(=O)(=O)O)c(c1)S(=O)(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H16 compound treatment 267.5 49.6 0.49 215.0 10.5 0.13 200.0 -13.883647798742 -0.197612625452152 0.2432 0.4482 3054849 HSCI1_000297 CCNC(=N)NCCC[C@H](N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H17 mock treatment 226.0 8.09 0.08 192.0 -12.5 -0.16 206.0 -7.883647798742 -0.112211744509296 -0.1088 -0.5234 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H18 mock treatment 260.0 42.1 0.41 202.0 -2.51 -0.03 182.0 -31.883647798742 -0.453815268280721 -0.0409 -0.0664 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H19 mock treatment 257.0 39.1 0.38 216.5 12.0 0.15 222.5 8.616352201258 0.122640678083559 0.3792 0.8807 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H20 mock treatment 269.0 51.1 0.5 236.0 31.5 0.39 194.5 -19.383647798742 -0.275896766316437 0.3575 0.5145 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H21 compound treatment 230.0 12.1 0.12 224.0 19.5 0.24 120.0 -93.883647798742 -1.33629103802357 -0.5627 -0.4127 3054896 HSCI1_000298 NC(=O)c1cn(C2OC(CO)[C@H](O)[C@@H]2O)c3ncnc(N)c13 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H22 compound treatment 245.0 27.1 0.27 121.0 -83.5 -1.04 186.0 -27.883647798742 -0.39688134765215 -0.6757 -0.5903 2063 HSCI1_000299 CCOC(=O)c1cnc2n(CC)ncc2c1NN=C(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H23 compound treatment 162.0 -55.9 -0.55 204.0 -0.506 -0.01 272.0 58.116352201258 0.827197945862122 0.1562 0.1572 606 HSCI1_000300 CNCCNS(=O)(=O)c1cccc2cnccc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 H24 compound treatment 144.0 -73.9 -0.73 150.0 -54.5 -0.68 190.5 -23.383647798742 -0.332830686945008 -1.0042 -0.957 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I01 compound treatment 62.0 -156.0 -1.53 116.0 -88.5 -1.1 114.0 -99.883647798742 -1.42169191896642 -2.3433 -0.991 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I02 compound treatment 300.0 82.1 0.81 222.0 17.5 0.22 181.0 -32.883647798742 -0.468048748437864 0.322 0.3359 662 HSCI1_000301 Cc1nc(c(o1)c2ccncc2)c3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I03 compound treatment 220.5 2.59 0.03 217.5 13.0 0.16 250.5 36.616352201258 0.521178122483554 0.409 0.7487 3054901 HSCI1_000302 Clc1cc(Cl)c(NC(=O)Nc2ccncc2)c(Cl)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I04 compound treatment 270.0 52.1 0.51 266.0 61.5 0.77 221.0 7.116352201258 0.101290457847844 0.7967 0.8592 2110413 HSCI1_000303 Cc1cc(C)c(/C=C/2\C(=O)Nc3ccccc23)[nH]1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I05 mock treatment 192.0 -25.9 -0.26 224.0 19.5 0.24 237.0 23.116352201258 0.329026140362128 0.1829 0.3794 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I06 mock treatment 137.0 -80.9 -0.8 166.0 -38.5 -0.48 238.0 24.116352201258 0.34325962051927 -0.5385 -0.5434 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I07 mock treatment 145.0 -72.9 -0.72 221.0 16.5 0.21 162.0 -51.883647798742 -0.738484871423575 -0.7221 -0.6877 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I08 mock treatment 147.5 -70.4 -0.69 133.0 -71.5 -0.89 200.5 -13.383647798742 -0.190495885373581 -1.0243 -0.895 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I09 compound treatment 197.0 -20.9 -0.21 168.0 -36.5 -0.45 142.5 -71.383647798742 -1.01603773448786 -0.968 -0.8551 2023 HSCI1_000304 CCCCn1c(=O)n(CCCC)c2ncn(CC(=O)C)c2c1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I10 compound treatment 260.0 42.1 0.41 235.0 30.5 0.38 156.0 -57.883647798742 -0.823885752366431 -0.0172 -0.0173 2196 HSCI1_000305 OS(=O)(=O)c1cc(c2c(NC(=O)c3ccc(NC(=O)c4ccc(NC(=O)Nc5ccc(cc5)C(=O)Nc6ccc(cc6)C(=O)Nc7ccc(c8cc(cc(c78)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)cc4)cc3)ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I11 compound treatment 216.5 -1.41 -0.01 257.0 52.5 0.65 169.0 -44.883647798742 -0.638850510323576 6.0E-4 6.0E-4 3054905 HSCI1_000306 Oc1ccc(cc1O)C(=O)/C(=C/c2ccc3oc(=O)[nH]c3c2)/C#N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I12 compound treatment 255.5 37.6 0.37 229.0 24.5 0.31 152.0 -61.883647798742 -0.880819672995002 -0.1188 -0.1185 3054907 HSCI1_000307 Cc1nc2cc3nc(cnc3cc2n1C)c4cccs4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I13 compound treatment 172.5 -45.4 -0.45 237.0 32.5 0.4 209.0 -4.883647798742 -0.069511304037868 -0.0646 -0.1064 3479224 HSCI1_000308 CC(=N)NCCCCC(N)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I14 compound treatment 258.0 40.1 0.39 279.5 75.0 0.93 259.0 45.116352201258 0.642162703819267 1.1378 0.948 2061 HSCI1_000309 Oc1cc(c2cc(ccc2c1N=Nc3ccc4ccccc4c3O)[N+](=O)[O-])S(=O)(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I15 compound treatment 158.0 -59.9 -0.59 162.0 -42.5 -0.53 173.0 -40.883647798742 -0.581916589695005 -0.9821 -0.9989 2087 HSCI1_000310 NC(CCC(=O)NC(CSN=O)C(=O)NCC(=O)O)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I16 compound treatment 169.0 -48.9 -0.48 204.0 -0.506 -0.01 167.5 -46.383647798742 -0.66020073055929 -0.6628 -0.8111 1870 HSCI1_000311 NC(=N)SCCc1cccc(CCSC(=N)N)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I17 compound treatment 229.0 11.1 0.11 188.0 -16.5 -0.21 193.5 -20.383647798742 -0.29013024647358 -0.2232 -0.6001 2408 HSCI1_000312 NCCC(O)(P(=O)(O)O)P(=O)(O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I18 compound treatment 190.0 -27.9 -0.27 175.0 -29.5 -0.37 192.0 -21.883647798742 -0.311480466709294 -0.5506 -0.9929 3054955 HSCI1_000313 Cc1ccc(cc1)S(=O)(=O)N[C@H](CCCCN)C(=O)CCl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I19 mock treatment 198.5 -19.4 -0.19 246.0 41.5 0.52 220.0 6.116352201258 0.0870569776907018 0.2383 0.4272 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I20 mock treatment 226.0 8.09 0.08 249.0 44.5 0.55 179.5 -34.383647798742 -0.489398968673578 0.0833 0.1121 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I21 mock treatment 173.5 -44.4 -0.44 254.0 49.5 0.62 161.0 -52.883647798742 -0.752718351580718 -0.3311 -0.3104 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I22 mock treatment 293.5 75.6 0.74 221.5 17.0 0.21 173.0 -40.883647798742 -0.581916589695005 0.2158 0.2229 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I23 compound treatment 247.0 29.1 0.29 199.0 -5.51 -0.07 157.5 -56.383647798742 -0.802535532130717 -0.3376 -0.395 1956 HSCI1_000314 N[C@H](CSCCB(O)O)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 I24 mock treatment 226.0 8.09 0.08 162.0 -42.5 -0.53 247.0 33.116352201258 0.471360941933555 0.0124 0.0174 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J01 mock treatment 208.5 -9.41 -0.09 220.5 16.0 0.2 234.0 20.116352201258 0.2863256998907 0.2268 0.6285 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J02 compound treatment 259.0 41.1 0.4 300.0 95.5 1.19 240.5 26.616352201258 0.378843320912127 1.1389 0.868 1005830 HSCI1_000315 Cc1cc(ccc1N=Nc2cc(c3ccccc3c2N)S(=O)(=O)O)c4ccc(N=Nc5cc(c6ccccc6c5N)S(=O)(=O)O)c(C)c4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J03 compound treatment 120.0 -97.9 -0.96 162.0 -42.5 -0.53 127.0 -86.883647798742 -1.23665667692357 -1.5761 -0.9524 573 HSCI1_000316 CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J04 compound treatment 383.5 166.0 1.63 697.0 492.0 6.13 343.0 129.116352201258 1.83777503701925 5.5435 0.839 1038990 HSCI1_000317 FC(F)(F)c1ccc2Sc3ccccc3N(CCCN4CCN(CCCl)CC4)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J05 mock treatment 202.0 -15.9 -0.16 206.0 1.49 0.02 210.0 -3.883647798742 -0.0552778238807253 -0.1116 -0.6677 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J06 mock treatment 253.0 35.1 0.35 208.0 3.49 0.04 223.5 9.616352201258 0.136874158240701 0.3035 0.8115 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J07 mock treatment 163.0 -54.9 -0.54 160.0 -44.5 -0.55 170.0 -43.883647798742 -0.624617030166433 -0.9927 -0.9979 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J08 mock treatment 236.0 18.1 0.18 238.5 34.0 0.42 257.0 43.116352201258 0.613695743504982 0.7015 0.9152 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J09 compound treatment 222.0 4.09 0.04 208.0 3.49 0.04 144.5 -69.383647798742 -0.987570774173572 -0.5218 -0.5275 3054961 HSCI1_000318 OCc1cc2ncnc(Nc3cc(Br)c(O)c(Br)c3)c2cc1CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J10 compound treatment 384.0 166.0 1.63 526.0 321.0 4.0 252.0 38.116352201258 0.542528342719268 3.5689 0.8188 1979 HSCI1_000319 Clc1ccc(cc1)C(c2ccc(Cl)cc2)[n+]3ccn(CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J11 compound treatment 267.0 49.1 0.48 451.0 246.0 3.07 326.0 112.116352201258 1.59580587434783 2.9728 0.8509 580 HSCI1_000320 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCN)c4ccccc34)c5ccccc15 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J12 compound treatment 198.0 -19.9 -0.2 251.5 47.0 0.59 185.0 -28.883647798742 -0.411114827809293 -0.0126 -0.017 3054964 HSCI1_000321 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CCC[C@]2(C)C3C(=O)C[C@@](C)(O[C@]13C)C=C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J13 compound treatment 186.0 -31.9 -0.31 209.0 4.49 0.06 150.0 -63.883647798742 -0.909286633309288 -0.674 -0.6995 907101 HSCI1_000322 NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J14 compound treatment 244.5 26.6 0.26 224.0 19.5 0.24 216.0 2.116352201258 0.030123057062131 0.3086 0.8616 3176334 HSCI1_000323 CC(C)[C@@]1(C)[C@@H]([C@H](OO)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@@]1(C)[C@@]5(O)C[C@@]3(C)[C@@]6(O)CCC(=C)[C@@H](O)[C@]46O5 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J15 compound treatment 202.5 -15.4 -0.15 261.0 56.5 0.7 189.0 -24.883647798742 -0.354180907180722 0.1141 0.1423 3054966 HSCI1_000324 C[C@@H]1CNCCCN1S(=O)(=O)c2cccc3cncc(C)c23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J16 compound treatment 303.0 85.1 0.84 194.5 -10.0 -0.12 226.0 12.116352201258 0.172457858633558 0.5111 0.5915 3176335 HSCI1_000325 CN1CCN(CCCC(=O)O[C@H]2[C@@H](O)[C@H]3C(C)(C)CC[C@H](O)[C@]3(C)[C@@]4(O)C(=O)C[C@@](C)(O[C@]24C)C=C)CC1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J17 compound treatment 209.0 -8.91 -0.09 298.0 93.5 1.16 138.0 -75.883647798742 -1.080088395195 -0.002 -0.0012 1049343 HSCI1_000326 CCC(C)C1NC(=O)C(NC(=O)c2c(N)c(=O)c(C)c3oc4c(C)ccc(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J18 compound treatment 464.0 246.0 2.42 350.5 146.0 1.82 323.0 109.116352201258 1.5531054338764 3.345 0.9827 3054969 HSCI1_000327 C[C@@]12CCC(=O)C=C2CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@@]4(O)C[C@H](O)[C@@H]31 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J19 mock treatment 244.0 26.1 0.26 258.0 53.5 0.67 213.0 -0.883647798742004 -0.0125773834092971 0.5256 0.7361 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J20 mock treatment 177.5 -40.4 -0.4 181.0 -23.5 -0.29 227.0 13.116352201258 0.186691338790701 -0.2909 -0.5509 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J21 mock treatment 231.0 13.1 0.13 199.5 -5.01 -0.06 154.5 -59.383647798742 -0.845235972602145 -0.4496 -0.5245 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J22 mock treatment 156.0 -61.9 -0.61 184.0 -20.5 -0.26 134.0 -79.883647798742 -1.13702231582357 -1.1558 -0.8789 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J23 compound treatment 145.5 -72.4 -0.71 205.0 0.494 0.01 131.0 -82.883647798742 -1.179722756295 -1.0891 -0.7901 3054970 HSCI1_000328 NC(=NCCSSCCN=C(N)N)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 J24 compound treatment 189.0 -28.9 -0.28 94.0 -111.0 -1.38 185.0 -28.883647798742 -0.411114827809293 -1.1963 -0.817 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K01 compound treatment 155.0 -62.9 -0.62 127.0 -77.5 -0.97 175.0 -38.883647798742 -0.55344962938072 -1.2344 -0.9693 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K02 compound treatment 138.0 -79.9 -0.79 232.0 27.5 0.34 229.0 15.116352201258 0.215158299104986 -0.1322 -0.1495 637 HSCI1_000329 C/C(=C(\C#N)/C(=O)Nc1ccc(OC(F)(F)F)cc1)/O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K03 compound treatment 221.0 3.09 0.03 232.0 27.5 0.34 227.0 13.116352201258 0.186691338790701 0.323 0.8257 391 HSCI1_000330 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K04 compound treatment 321.0 103.0 1.01 296.0 91.5 1.14 526.0 312.116352201258 4.44250190577637 3.8086 0.8108 3055003 HSCI1_000331 O=C1c2ccccc2-[n+]3ccc4c5ccccc5[nH]c4c13 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K05 compound treatment 175.5 -42.4 -0.42 399.0 194.0 2.42 409.0 195.116352201258 2.77718472739067 2.7609 0.7444 3055004 HSCI1_000332 Fc1ccc(cc1)C(=O)/C=C/2\C(=O)Nc3ccc(Br)cc23 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K06 compound treatment 229.0 11.1 0.11 335.0 130.0 1.63 292.5 78.616352201258 1.11898428908355 1.6474 0.8336 3176336 HSCI1_000333 CC(C)(C)C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c3ccccc32 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K07 mock treatment 139.0 -78.9 -0.78 219.5 15.0 0.19 189.0 -24.883647798742 -0.354180907180722 -0.5451 -0.6238 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K08 mock treatment 238.0 20.1 0.2 261.0 56.5 0.7 235.0 21.116352201258 0.300559180047842 0.6939 0.8781 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K09 mock treatment 226.5 8.59 0.08 237.0 32.5 0.4 215.0 1.116352201258 0.0158895769049883 0.2916 0.7048 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K10 mock treatment 254.0 36.1 0.36 225.0 20.5 0.26 243.0 29.116352201258 0.414427021304984 0.5917 0.982 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K11 compound treatment 233.5 15.6 0.15 257.0 52.5 0.65 189.0 -24.883647798742 -0.354180907180722 0.2616 0.3445 3055006 HSCI1_000334 COc1cccc(c1)c2cc(NCc3ccc4OCOc4c3)nc(N)n2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K12 compound treatment 216.0 -1.91 -0.02 263.0 58.5 0.73 230.0 16.116352201258 0.229391779262129 0.5422 0.7096 3176337 HSCI1_000335 COc1ccc(cc1)c2cnc3c(cnn3c2)c4ccsc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K13 compound treatment 223.0 5.09 0.05 177.0 -27.5 -0.34 136.5 -77.383647798742 -1.10143861543071 -0.8048 -0.6971 3055009 HSCI1_000336 CC1=C(O)C(=O)[C@H]2O[C@H]2C1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K14 compound treatment 240.0 22.1 0.22 268.0 63.5 0.79 176.0 -37.883647798742 -0.539216149223577 0.2708 0.2759 1709 HSCI1_000337 NCCCC(O)(P(=O)(O)O)P(=O)(O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K15 mock treatment 259.5 41.6 0.41 236.0 31.5 0.39 206.5 -7.383647798742 -0.105095004430725 0.4021 0.6974 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K16 mock treatment 285.0 67.1 0.66 241.0 36.5 0.45 236.0 22.116352201258 0.314792660204985 0.8254 0.9584 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K17 compound treatment 293.0 75.1 0.74 163.0 -41.5 -0.52 254.0 40.116352201258 0.570995303033554 0.4579 0.429 3176338 HSCI1_000338 CCCCCCCCCCCCCCCCOCC(COCC(F)(F)F)OP(=O)(O)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K18 compound treatment 171.0 -46.9 -0.46 298.5 94.0 1.17 271.5 57.616352201258 0.820081205783551 0.8828 0.5877 1932 HSCI1_000339 OP(=O)(O)Oc1cccc2ccccc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K19 compound treatment 253.0 35.1 0.35 226.5 22.0 0.27 245.5 31.616352201258 0.450010721697841 0.6174 0.98 95 HSCI1_000340 CCCCCC(O)/C=C/C=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K20 compound treatment 256.0 38.1 0.37 267.0 62.5 0.78 178.0 -35.883647798742 -0.510749188909292 0.3709 0.3696 3176339 HSCI1_000341 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)C[C@H](O)C3=C)\CCC[C@]12C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K21 mock treatment 271.0 53.1 0.52 177.0 -27.5 -0.34 180.0 -33.883647798742 -0.482282228595006 -0.1746 -0.2212 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K22 mock treatment 255.5 37.6 0.37 265.0 60.5 0.75 264.5 50.616352201258 0.720446844683552 1.0645 0.9624 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K23 compound treatment 120.0 -97.9 -0.96 155.5 -49.0 -0.61 151.0 -62.883647798742 -0.895053153152145 -1.4256 -0.9832 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 K24 mock treatment 229.0 11.1 0.11 270.0 65.5 0.82 231.0 17.116352201258 0.243625259419272 0.6746 0.786 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L01 mock treatment 153.5 -64.4 -0.63 149.5 -55.0 -0.69 257.0 43.116352201258 0.613695743504982 -0.4073 -0.3646 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L02 compound treatment 257.5 39.6 0.39 234.0 29.5 0.37 214.0 0.116352201257996 0.00165609674784556 0.438 0.8179 594 HSCI1_000342 Cc1nc2sccn2c(=O)c1CCN3CCC(=C(c4ccccc4)c5ccc(F)cc5)CC3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L03 compound treatment 266.0 48.1 0.47 687.0 482.0 6.01 288.0 74.116352201258 1.05493362837641 4.3518 0.7111 581 HSCI1_000343 Cn1cc(C2=C(C(=O)NC2=O)c3c4CC(CN)CCn4c5ccccc35)c6ccccc16 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L04 compound treatment 239.5 21.6 0.21 299.0 94.5 1.18 415.0 201.116352201258 2.86258560833353 2.4549 0.7913 1002019 HSCI1_000344 COc1ccc2C3CC[C@]4(C)[C@H](CCC4C3CCc2c1)NCCCCCCN5C(=O)C=CC5=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L05 compound treatment 222.5 4.59 0.05 202.5 -2.01 -0.02 156.0 -57.883647798742 -0.823885752366431 -0.464 -0.5621 3055016 HSCI1_000345 COc1cc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(Oc5ccccc5)cc4)c2cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L06 compound treatment 156.0 -61.9 -0.61 199.0 -5.51 -0.07 147.0 -66.883647798742 -0.951987073780716 -0.9411 -0.831 2348 HSCI1_000346 COc1ccc2C3CC[C@]4(C)[C@H](CCC4C3CCc2c1)NCCCCCCN5C(=O)CCC5=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L07 mock treatment 235.0 17.1 0.17 237.0 32.5 0.4 242.0 28.116352201258 0.400193541147841 0.5618 0.9466 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L08 mock treatment 252.5 34.6 0.34 169.0 -35.5 -0.44 219.0 5.116352201258 0.0728234975335591 -0.0167 -0.0297 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L09 mock treatment 255.0 37.1 0.37 257.0 52.5 0.65 204.0 -9.883647798742 -0.140678704823581 0.507 0.6654 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L10 mock treatment 254.0 36.1 0.36 264.0 59.5 0.74 202.0 -11.883647798742 -0.169145665137867 0.5352 0.638 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L11 compound treatment 124.0 -93.9 -0.92 191.0 -13.5 -0.17 140.5 -73.383647798742 -1.04450469480214 -1.2339 -0.8782 582 HSCI1_000347 CN(C)CC1CCn2c(C1)c(C3=C(C(=O)NC3=O)c4cn(C)c5ccccc45)c6ccccc26 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L12 compound treatment 254.5 36.6 0.36 231.0 26.5 0.33 226.0 12.116352201258 0.172457858633558 0.498 0.9614 595 HSCI1_000348 Fc1ccc(cc1)C(=C2CCN(CCn3c(=O)c4ccccc4[nH]c3=S)CC2)c5ccc(F)cc5 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L13 compound treatment 269.0 51.1 0.5 253.0 48.5 0.6 194.0 -19.883647798742 -0.283013506395009 0.4756 0.5694 3176385 HSCI1_000349 NCC1OC(OC2C(N)CC(N)C(O)C2O[C@@H]3OC[C@H](COCC4OCC(O)C(O)C4N)[C@@H]3O)C(N)C(O)C1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L14 compound treatment 341.0 123.0 1.21 305.5 101.0 1.26 301.0 87.116352201258 1.23996887041926 2.1416 0.9999 3055065 HSCI1_000350 Nc1ncn([C@@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L15 mock treatment 228.5 10.6 0.1 221.0 16.5 0.21 197.0 -16.883647798742 -0.24031306592358 0.04 0.1202 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L16 mock treatment 270.0 52.1 0.51 240.0 35.5 0.44 277.0 63.116352201258 0.898365346647836 1.0699 0.9511 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L17 compound treatment 328.0 110.0 1.08 291.0 86.5 1.08 305.5 91.616352201258 1.3040195311264 2.0004 0.9959 372 HSCI1_000351 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L18 compound treatment 258.5 40.6 0.4 222.5 18.0 0.22 257.0 43.116352201258 0.613695743504982 0.7143 0.9328 1367 HSCI1_000352 Cc1cc(O)ccc1Cl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L19 compound treatment 199.5 -18.4 -0.18 397.0 192.0 2.4 301.0 87.116352201258 1.23996887041926 1.9954 0.7376 3055069 HSCI1_000353 CC/C(=C(\c1ccc(O)cc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L20 compound treatment 251.0 33.1 0.33 228.0 23.5 0.29 226.0 12.116352201258 0.172457858633558 0.4565 0.9702 2237 HSCI1_000354 FS(=O)(=O)Cc1ccccc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L21 mock treatment 282.5 64.6 0.64 262.0 57.5 0.72 240.0 26.116352201258 0.371726580833556 0.9951 0.9688 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L22 mock treatment 153.0 -64.9 -0.64 143.5 -61.0 -0.76 224.0 10.116352201258 0.143990898319273 -0.7245 -0.7222 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L23 mock treatment 263.0 45.1 0.44 206.0 1.49 0.02 208.0 -5.883647798742 -0.0837447841950107 0.2186 0.4836 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 L24 compound treatment 193.0 -24.9 -0.25 232.0 27.5 0.34 155.0 -58.883647798742 -0.838119232523574 -0.4278 -0.4561 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M01 compound treatment 80.0 -138.0 -1.36 134.0 -70.5 -0.88 141.0 -72.883647798742 -1.03738795472357 -1.8897 -0.9837 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M02 compound treatment 176.0 -41.9 -0.41 146.0 -58.5 -0.73 254.0 40.116352201258 0.570995303033554 -0.3292 -0.3248 1900 HSCI1_000355 COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M03 compound treatment 142.0 -75.9 -0.75 247.5 43.0 0.54 232.5 18.616352201258 0.264975479654986 0.0307 0.0321 3055072 HSCI1_000356 Cn1cc(/C=C/2\C(=O)Nc3ccc(cc23)S(=O)(=O)N)c4ccccc14 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M04 compound treatment 316.0 98.1 0.97 287.0 82.5 1.03 194.5 -19.383647798742 -0.275896766316437 0.9913 0.69 292 HSCI1_000357 O=C1NCc2c1c3c4ccccc4[nH]c3c5[nH]c6ccccc6c25 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M05 compound treatment 242.0 24.1 0.24 299.5 95.0 1.18 193.5 -20.383647798742 -0.29013024647358 0.6524 0.5257 907290 HSCI1_000358 CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](O)[C@@]3(C)O[C@](C)(CC(=O)[C@@]32O)C=C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M06 compound treatment 135.0 -82.9 -0.82 191.0 -13.5 -0.17 134.0 -79.883647798742 -1.13702231582357 -1.2248 -0.8688 3055076 HSCI1_000359 NS(=O)(=O)c1ccc(N/C=C/2\C(=O)Nc3ccccc23)cc1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M07 compound treatment 134.0 -83.9 -0.83 283.5 79.0 0.98 169.0 -44.883647798742 -0.638850510323576 -0.2777 -0.1936 3055122 HSCI1_000360 OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c5cccc1c52 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M08 compound treatment 149.5 -68.4 -0.67 133.0 -71.5 -0.89 139.5 -74.383647798742 -1.05873817495929 -1.5142 -0.9841 3176387 HSCI1_000361 Nc1cccc(c1)c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M09 mock treatment 169.0 -48.9 -0.48 250.0 45.5 0.57 164.0 -49.883647798742 -0.71001791110929 -0.3608 -0.3509 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M10 mock treatment 159.0 -58.9 -0.58 144.5 -60.0 -0.75 229.0 15.116352201258 0.215158299104986 -0.6421 -0.6619 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M11 mock treatment 244.5 26.6 0.26 225.5 21.0 0.26 265.0 51.116352201258 0.727563584762123 0.7221 0.8847 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M12 mock treatment 201.0 -16.9 -0.17 239.0 34.5 0.43 201.5 -12.383647798742 -0.176262405216438 0.0501 0.1017 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M13 mock treatment 242.0 24.1 0.24 252.0 47.5 0.59 231.0 17.116352201258 0.243625259419272 0.619 0.9074 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M14 mock treatment 258.0 40.1 0.39 272.0 67.5 0.84 199.0 -14.883647798742 -0.211846105609295 0.5908 0.6203 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M15 compound treatment 215.0 -2.91 -0.03 216.0 11.5 0.14 215.0 1.116352201258 0.0158895769049883 0.0753 0.5125 2796 HSCI1_000362 CCCCCCCC/C=C\CCCCCCCC(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M16 compound treatment 296.5 78.6 0.77 301.0 96.5 1.2 253.0 39.116352201258 0.556761822876411 1.4619 0.9531 3176388 HSCI1_000363 COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@@H]2c3cc4OCOc4cc3CCN5CCC[C@]25C=C1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M17 compound treatment 231.0 13.1 0.13 261.0 56.5 0.7 223.0 9.116352201258 0.12975741816213 0.5555 0.7641 1000076 HSCI1_000364 CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M18 compound treatment 196.0 -21.9 -0.22 193.0 -11.5 -0.14 151.0 -62.883647798742 -0.895053153152145 -0.724 -0.7771 2058 HSCI1_000365 OC(=O)C1C(C2CCC1O2)C(=O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M19 compound treatment 217.5 -0.415 0.0 264.0 59.5 0.74 236.0 22.116352201258 0.314792660204985 0.6072 0.7542 1000072 HSCI1_000366 CC(C)OP(=O)(F)OC(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M20 compound treatment 367.0 149.0 1.47 574.0 369.0 4.6 277.0 63.116352201258 0.898365346647836 4.0229 0.8188 3176389 HSCI1_000367 CC(=O)O[C@@H]1CC2[C@@]3(C)CCCC(C)(C)C3CC[C@@]2(C)C4CC=C(C=O)[C@H](C=O)[C@@]14C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M21 compound treatment 281.0 63.1 0.62 443.0 238.0 2.97 297.0 83.116352201258 1.18303494979069 2.7565 0.8463 3176390 HSCI1_000368 CCCC(=O)OC1C(OC2COP(O)(O)OC12)n3cnc4c(=O)[nH]c(NOC(=C)CC)nc34 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M22 compound treatment 137.5 -80.4 -0.79 191.5 -13.0 -0.16 180.0 -33.883647798742 -0.482282228595006 -0.829 -0.881 3055129 HSCI1_000369 CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@@]21C)c5ccc(cc5)N(C)C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M23 compound treatment 168.5 -49.4 -0.49 201.0 -3.51 -0.04 130.0 -83.883647798742 -1.19395623645214 -0.9954 -0.7716 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 M24 mock treatment 221.0 3.09 0.03 208.0 3.49 0.04 219.0 5.116352201258 0.0728234975335591 0.0847 0.94 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N01 mock treatment 160.0 -57.9 -0.57 266.0 61.5 0.77 227.0 13.116352201258 0.186691338790701 0.2209 0.227 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N02 compound treatment 182.0 -35.9 -0.35 154.5 -50.0 -0.62 254.5 40.616352201258 0.578112043112125 -0.2299 -0.2498 600 HSCI1_000370 COC(=O)/C=C/c1cc(O)ccc1O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N03 compound treatment 161.0 -56.9 -0.56 132.0 -72.5 -0.9 102.0 -111.883647798742 -1.59249368085214 -1.7642 -0.9215 630 HSCI1_000371 COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C/C=C/c3ccc(Cl)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N04 compound treatment 282.0 64.1 0.63 244.5 40.0 0.5 177.5 -36.383647798742 -0.517865928987863 0.3528 0.369 2283 HSCI1_000372 CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N05 compound treatment 215.0 -2.91 -0.03 197.5 -7.01 -0.09 174.0 -39.883647798742 -0.567683109537863 -0.3947 -0.6863 629 HSCI1_000373 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2CN(C)C/C=C/c3ccc(Cl)cc3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N06 compound treatment 165.0 -52.9 -0.52 257.0 52.5 0.65 239.0 25.116352201258 0.357493100676413 0.2832 0.3115 1884 HSCI1_000374 Cc1ccnc(N)c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N07 compound treatment 414.0 196.0 1.93 378.0 173.0 2.16 252.0 38.116352201258 0.542528342719268 2.6751 0.9075 1918023 HSCI1_000375 CC[n+]1c(/C=C/N(C)c2ccccc2)n(c3ccccc3)c4ccc(cc14)c5nc6ccccc6s5 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N08 compound treatment 232.0 14.1 0.14 197.0 -7.51 -0.09 163.0 -50.883647798742 -0.724251391266432 -0.3921 -0.5275 2344 HSCI1_000376 FC(F)(F)C(=O)CC(=O)c1cccs1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N09 mock treatment 240.0 22.1 0.22 237.0 32.5 0.4 213.0 -0.883647798742004 -0.0125773834092971 0.3519 0.7657 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N10 mock treatment 183.0 -34.9 -0.34 135.0 -69.5 -0.87 130.0 -83.883647798742 -1.19395623645214 -1.3876 -0.9163 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N11 mock treatment 241.5 23.6 0.23 262.0 57.5 0.72 235.0 21.116352201258 0.300559180047842 0.721 0.8895 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N12 mock treatment 125.0 -92.9 -0.91 114.0 -90.5 -1.13 162.0 -51.883647798742 -0.738484871423575 -1.6052 -0.9856 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N13 mock treatment 180.5 -37.4 -0.37 189.0 -15.5 -0.19 206.0 -7.883647798742 -0.112211744509296 -0.3889 -0.9029 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N14 mock treatment 118.5 -99.4 -0.98 141.0 -63.5 -0.79 140.0 -73.883647798742 -1.05162143488071 -1.6288 -0.9933 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N15 compound treatment 140.5 -77.4 -0.76 160.5 -44.0 -0.55 129.0 -84.883647798742 -1.20818971660928 -1.4539 -0.9503 1000048 HSCI1_000377 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N16 compound treatment 222.5 4.59 0.05 212.0 7.49 0.09 185.0 -28.883647798742 -0.411114827809293 -0.1574 -0.3713 2187 HSCI1_000378 O=C(NC1CCCCC1)NC2CCCCC2 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N17 compound treatment 246.0 28.1 0.28 231.0 26.5 0.33 198.0 -15.883647798742 -0.226079585766438 0.2196 0.4516 2083 HSCI1_000379 CC(CCC(=O)NCC(=O)O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N18 compound treatment 111.0 -107.0 -1.05 151.0 -53.5 -0.67 135.0 -78.883647798742 -1.12278883566643 -1.6406 -0.9783 1934 HSCI1_000380 NNC(=N)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N19 compound treatment 127.0 -90.9 -0.89 243.0 38.5 0.48 348.5 134.616352201258 1.91605917788354 0.8664 0.3995 30 HSCI1_000381 COC(=O)C1=C(C)NC(=C(C1c2ccccc2C(F)(F)F)[N+](=O)[O-])C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N20 compound treatment 420.5 203.0 1.99 460.0 255.0 3.18 349.0 135.116352201258 1.92317591796211 4.0988 0.9715 420 HSCI1_000382 CCN1C(=O)C=CC1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N21 compound treatment 404.0 186.0 1.83 322.0 117.0 1.46 301.0 87.116352201258 1.23996887041926 2.6183 0.9872 3054850 HSCI1_000383 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N22 compound treatment 212.0 -5.91 -0.06 225.0 20.5 0.26 252.0 38.116352201258 0.542528342719268 0.427 0.7088 2003 HSCI1_000384 CNC1CCc2cc(OC)c(OC)c(OC)c2-c3ccc(OC)c(=O)cc13 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N23 mock treatment 259.0 41.1 0.4 247.5 43.0 0.54 186.0 -27.883647798742 -0.39688134765215 0.3135 0.4021 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 N24 compound treatment 145.0 -72.9 -0.72 89.0 -116.0 -1.44 197.0 -16.883647798742 -0.24031306592358 -1.3837 -0.8512 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O01 compound treatment 131.5 -86.4 -0.85 152.0 -52.5 -0.65 143.0 -70.883647798742 -1.00892099440929 -1.4511 -0.9853 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O02 mock treatment 146.0 -71.9 -0.71 256.0 51.5 0.64 232.0 18.116352201258 0.257858739576414 0.1105 0.1117 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O03 compound treatment 190.0 -27.9 -0.27 501.0 296.0 3.69 576.0 362.116352201258 5.1541759136335 4.9492 0.7798 3054852 HSCI1_000385 O=C/1Nc2ccc(cc2\C1=C\c3ccc[nH]3)c4cccnc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O04 compound treatment 281.0 63.1 0.62 379.0 174.0 2.17 436.5 222.616352201258 3.1686054317121 3.4426 0.8845 3176393 HSCI1_000386 Cn1nc(N)c2cn(C3OC(CO)C(O)C3O)c4ncnc1c24 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O05 compound treatment 174.0 -43.9 -0.43 257.0 52.5 0.65 361.0 147.116352201258 2.09397767984782 1.3369 0.5979 3176394 HSCI1_000387 C1CCC(CC1)Nc2nc(Nc3ccc(cc3)N4CCOCC4)nc5[nH]cnc25 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O06 compound treatment 194.0 -23.9 -0.24 163.0 -41.5 -0.52 294.0 80.116352201258 1.14033450931926 0.224 0.1758 575 HSCI1_000388 O=C1NC(=O)C(=C1c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O07 compound treatment 166.0 -51.9 -0.51 241.5 37.0 0.46 380.0 166.116352201258 2.36441380283353 1.3361 0.5426 3176395 HSCI1_000389 CCCCN1C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@@H](N2C1=O)c5ccc(OC)cc5 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O08 compound treatment 190.5 -27.4 -0.27 230.0 25.5 0.32 203.0 -10.883647798742 -0.154912184980724 -0.0619 -0.1393 2116778 HSCI1_000390 CCOC(=O)c1cnc2oc3ccc(O)cc3c2c1c4ccccc4 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O09 compound treatment 233.0 15.1 0.15 382.0 177.0 2.21 275.5 61.616352201258 0.877015126412122 1.8684 0.7841 3176396 HSCI1_000391 CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c3ncn(C(C)C)c3n1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O10 compound treatment 286.5 68.6 0.68 298.0 93.5 1.16 259.0 45.116352201258 0.642162703819267 1.4328 0.9608 676 HSCI1_000392 COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O11 mock treatment 162.0 -55.9 -0.55 158.0 -46.5 -0.58 130.0 -83.883647798742 -1.19395623645214 -1.3415 -0.9338 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O12 mock treatment 150.5 -67.4 -0.66 252.0 47.5 0.59 243.5 29.616352201258 0.421543761383555 0.2018 0.2051 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O13 mock treatment 215.0 -2.91 -0.03 162.0 -42.5 -0.53 246.5 32.616352201258 0.464244201854983 -0.0542 -0.0769 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O14 mock treatment 180.5 -37.4 -0.37 158.0 -46.5 -0.58 157.0 -56.883647798742 -0.809652272209289 -1.0145 -0.9558 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O15 compound treatment 231.5 13.6 0.13 255.0 50.5 0.63 238.0 24.116352201258 0.34325962051927 0.6385 0.876 1398 HSCI1_000393 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O16 compound treatment 267.0 49.1 0.48 186.5 -18.0 -0.22 168.0 -45.883647798742 -0.653083990480719 -0.2276 -0.2701 2060355 HSCI1_000394 CC1=C(C=C)/C(=C/c2[nH]c(Cc3[nH]c(\C=C\4/NC(=O)C(=C4C)C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)/NC1=O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O17 compound treatment 245.0 27.1 0.27 161.0 -43.5 -0.54 254.0 40.116352201258 0.570995303033554 0.1707 0.2054 1929 HSCI1_000395 Nc1cccc2c(=O)[nH]ccc12 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O18 compound treatment 309.0 91.1 0.9 313.0 108.0 1.35 290.0 76.116352201258 1.08340058869069 1.9233 0.9862 2286 HSCI1_000396 CCSC(=N)N 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O19 compound treatment 236.0 18.1 0.18 241.0 36.5 0.45 225.0 11.116352201258 0.158224378476415 0.4565 0.8897 23 HSCI1_000397 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O20 compound treatment 258.0 40.1 0.39 315.0 110.0 1.38 185.0 -28.883647798742 -0.411114827809293 0.785 0.527 3054913 HSCI1_000398 Cc1ccc(cc1)S(=O)(=O)N[C@H](Cc2ccccc2)C(=O)CCl 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O21 compound treatment 436.5 219.0 2.15 304.0 99.5 1.24 764.0 550.116352201258 7.83007018317633 6.4783 0.7887 3176397 HSCI1_000399 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C/3\C[C@@H](O)C[C@H](O)C3=C)/CCC[C@@]12C 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O22 compound treatment 246.0 28.1 0.28 261.0 56.5 0.7 241.0 27.116352201258 0.385960060990699 0.7887 0.9292 988 HSCI1_000400 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O23 compound treatment 137.0 -80.9 -0.8 148.0 -56.5 -0.7 162.0 -51.883647798742 -0.738484871423575 -1.2925 -0.9987 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 O24 mock treatment 257.5 39.6 0.39 225.0 20.5 0.26 280.0 66.116352201258 0.941065787119264 0.9156 0.872 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P01 mock treatment 160.0 -57.9 -0.57 219.0 14.5 0.18 166.0 -47.883647798742 -0.681550950795004 -0.6184 -0.682 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P02 compound treatment 125.0 -92.9 -0.91 180.0 -24.5 -0.31 169.5 -44.383647798742 -0.631733770245005 -1.069 -0.9274 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P03 mock treatment 172.0 -45.9 -0.45 243.0 38.5 0.48 255.0 41.116352201258 0.585228783190696 0.3538 0.4014 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P04 mock treatment 139.5 -78.4 -0.77 243.5 39.0 0.49 255.0 41.116352201258 0.585228783190696 0.1727 0.1593 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P05 mock treatment 145.0 -72.9 -0.72 143.5 -61.0 -0.76 261.0 47.116352201258 0.670629664133553 -0.4659 -0.3751 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P06 mock treatment 277.0 59.1 0.58 234.0 29.5 0.37 131.0 -82.883647798742 -1.179722756295 -0.1333 -0.0976 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P07 mock treatment 284.0 66.1 0.65 261.0 56.5 0.7 272.0 58.116352201258 0.827197945862122 1.2594 0.9949 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P08 mock treatment 356.0 138.0 1.36 143.5 -61.0 -0.76 253.0 39.116352201258 0.556761822876411 0.6675 0.4036 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P09 mock treatment 167.5 -50.4 -0.5 230.0 25.5 0.32 236.5 22.616352201258 0.321909400283556 0.0827 0.1231 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P10 mock treatment 253.0 35.1 0.35 260.5 56.0 0.7 227.5 13.616352201258 0.193808078869272 0.7139 0.8902 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P11 mock treatment 291.5 73.6 0.72 151.0 -53.5 -0.67 255.0 41.116352201258 0.585228783190696 0.3713 0.3243 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P12 mock treatment 249.0 31.1 0.31 241.0 36.5 0.45 222.5 8.616352201258 0.122640678083559 0.5099 0.9081 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P13 mock treatment 318.0 100.0 0.99 282.0 77.5 0.97 227.5 13.616352201258 0.193808078869272 1.2379 0.8889 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P14 mock treatment 269.5 51.6 0.51 314.5 110.0 1.37 241.0 27.116352201258 0.385960060990699 1.3069 0.8649 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P15 mock treatment 331.0 113.0 1.11 363.0 158.0 1.97 268.0 54.116352201258 0.770264025233552 2.2271 0.9304 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P16 mock treatment 271.0 53.1 0.52 225.0 20.5 0.26 245.5 31.616352201258 0.450010721697841 0.7089 0.964 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P17 mock treatment 262.0 44.1 0.43 291.0 86.5 1.08 255.0 41.116352201258 0.585228783190696 1.2104 0.9307 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P18 mock treatment 30.5 -187.0 -1.84 216.5 12.0 0.15 199.0 -14.883647798742 -0.211846105609295 -1.1011 -0.5911 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P19 mock treatment 184.0 -33.9 -0.33 164.0 -40.5 -0.5 253.0 39.116352201258 0.556761822876411 -0.1626 -0.1977 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P20 mock treatment 239.5 21.6 0.21 215.0 10.5 0.13 242.5 28.616352201258 0.407310281226413 0.4333 0.9072 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P21 mock treatment 280.0 62.1 0.61 251.5 47.0 0.59 278.5 64.616352201258 0.91971556688355 1.2217 0.9776 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P22 mock treatment 262.0 44.1 0.43 161.0 -43.5 -0.54 211.5 -2.383647798742 -0.0339276036450112 -0.0819 -0.1178 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P23 mock treatment 190.5 -27.4 -0.27 209.0 4.49 0.06 200.0 -13.883647798742 -0.197612625452152 -0.2376 -0.7006 1131.0077 GeneExprHTS(1131.0077) GE-HTSNotch1Inhibition 1131.0077.2105 P24 compound treatment 187.0 -30.9 -0.3 136.0 -68.5 -0.85 178.0 -35.883647798742 -0.510749188909292 -0.9632 -0.9262