ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A01 compound treatment 1.0087 0.148 1.74 1.0989 0.205 3.08 3.4075 0.9634 3118959 ChemDiv3_003873 COC(=O)C(CC(C)C)N1C=C(C(C(=C1)C(=O)OC)c2ccc(Br)cc2)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A02 compound treatment 1.0041 0.143 1.68 1.06 0.166 2.49 2.9544 0.9817 3023755 ChemDiv3_003874 CN(C)c1ccc(cc1)n2cccc2C=C3C(=O)N(C)C(=S)N(C)C3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A03 compound treatment 1.0357 0.175 2.06 1.0909 0.197 2.96 3.5458 0.9842 1344150 ChemDiv3_003875 CSc1nnc-2c(OC(C)Nc3ccccc32)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A04 compound treatment 1.0117 0.151 1.77 1.0486 0.154 2.32 2.8966 0.9911 3118960 ChemDiv3_003876 O=C(CSc1nnc(COc2ccccc2)o1)Nc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A05 compound treatment 1.0242 0.164 1.92 1.0444 0.15 2.26 2.9558 0.9967 3023867 ChemDiv3_003877 CCc1ccc2NC(=O)/C(=C/3\SC(=N)NC3=O)/c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A06 compound treatment 0.9882 0.128 1.5 1.0464 0.152 2.29 2.6784 0.9788 1867181 ChemDiv3_003878 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CNC(C)(C)C)cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A07 compound treatment 1.0796 0.219 2.57 1.0503 0.156 2.35 3.4781 0.999 3118961 ChemDiv3_003879 CCc1ccc(/C=N/n2c(C)nnc2n3nc(C)cc3C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A08 compound treatment 1.0133 0.153 1.79 1.052 0.158 2.37 2.9456 0.9904 1292139 ChemDiv3_003880 O=C(N1c2ccccc2Sc3ccccc13)c4cccs4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A09 compound treatment 1.0035 0.143 1.68 1.0476 0.153 2.31 2.8181 0.9878 3119097 ChemDiv3_003881 CN1C(=O)/C(=C/2\S\C(=N/c3ccc(F)cc3)\NC2=O)/c4cc(Br)cc(C)c14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A10 compound treatment 1.0159 0.155 1.82 1.0435 0.149 2.25 2.8774 0.9946 3023868 ChemDiv3_003882 CCCn1c(C)cc(C)c(C#N)c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A11 compound treatment 1.0592 0.199 2.33 1.0345 0.14 2.11 3.1413 0.9988 3023869 ChemDiv3_003883 CC(Cc1ccccc1)[n+]2[cH-]/c(=N\C(=O)N)/on2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A12 compound treatment 0.9933 0.133 1.56 1.0377 0.143 2.16 2.6273 0.9872 1249817 ChemDiv3_003884 COc1cccc(CN2CCN(CC2)C(=O)c3cccs3)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A13 compound treatment 1.0257 0.165 1.94 1.0924 0.198 2.98 3.479 0.9782 3119098 ChemDiv3_003885 Cc1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)NCC4CCCO4)c5ccccc25)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A14 compound treatment 1.0186 0.158 1.86 1.0189 0.125 1.88 2.6383 1.0 3023870 ChemDiv3_003886 C(Cc1c[nH]c2ccccc12)NCc3cccc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A15 compound treatment 1.0181 0.158 1.85 1.0469 0.153 2.3 2.9314 0.9942 1549146 ChemDiv3_003887 Clc1ccc(SCC(=O)Nc2ccc(cc2)c3nc4ncccc4o3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A16 compound treatment 0.9946 0.134 1.57 1.0473 0.153 2.3 2.7409 0.9827 3023871 ChemDiv3_003888 CCCN(CCC)C1=C(N(CC(=O)N)S(=O)(=O)c2ccccc12)C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A17 compound treatment 0.9931 0.133 1.56 1.0063 0.112 1.69 2.2921 0.9992 1118860 ChemDiv3_003889 CCN(CC)CCC(=O)N1N=C(CC1c2ccc(OC)cc2)c3ccc(C)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A18 compound treatment 1.0235 0.163 1.91 1.0653 0.171 2.57 3.172 0.9893 1173412 ChemDiv3_003890 Cc1cc(C)cc(Oc2coc3cc(OCC(=O)NCc4ccccc4)ccc3c2=O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A19 compound treatment 0.9905 0.13 1.52 1.0223 0.128 1.93 2.4408 0.9933 1387978 ChemDiv3_003891 CN(C)C1CS(=O)(=O)CC1N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A20 compound treatment 0.9797 0.119 1.4 0.9894 0.0953 1.43 2.002 0.9999 1867723 ChemDiv3_003892 COc1ccccc1COc2ccc3c4CCCCCc4c(=O)oc3c2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A21 compound treatment 0.9467 0.0862 1.01 0.986 0.0918 1.38 1.6915 0.9883 1361724 ChemDiv3_003893 O=C(NCc1ccccc1)NC2CCS(=O)(=O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A22 compound treatment 0.9484 0.0878 1.03 0.9654 0.0712 1.07 1.486 0.9998 1233165 ChemDiv3_003894 Cc1oc(cc1COc2ccc3c(C)c(Cc4ccccc4)c(=O)oc3c2C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A23 mock treatment 0.9522 0.0916 1.08 0.9842 0.0901 1.35 1.7179 0.9935 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 A24 mock treatment 0.9373 0.0768 0.9 0.9942 0.1 1.5 1.7012 0.9699 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B01 compound treatment 1.0068 0.146 1.72 1.062 0.168 2.52 2.9979 0.9824 3119099 ChemDiv3_003895 CN(/N=C/c1ccccc1)C2=NS(=O)(=O)c3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B02 compound treatment 0.9917 0.131 1.54 1.0602 0.166 2.5 2.8543 0.973 3119100 ChemDiv3_003896 COC(=O)C1=C(C)N/C(=C/c2cc(C)n(c2C)c3ccc(OC)c(Cl)c3)/C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B03 compound treatment 0.9433 0.0828 0.97 1.0485 0.154 2.32 2.3281 0.9253 3023872 ChemDiv3_003897 COc1cccc(C=C2C(=O)c3ccccc3C2=O)c1OC(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B04 compound treatment 1.0012 0.141 1.65 1.057 0.163 2.45 2.8993 0.9816 3023873 ChemDiv3_003898 Cc1ccc(cc1)c2c[n+]([O-])c3CCCc3[n+]2[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B05 compound treatment 1.0276 0.167 1.96 1.039 0.145 2.18 2.9268 0.9986 3119101 ChemDiv3_003899 O=c1[nH]c2ccccc2n1CCCSc3nc4ccccc4[nH]3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B06 compound treatment 1.0247 0.164 1.93 1.0598 0.166 2.49 3.1238 0.9919 1401658 ChemDiv3_003900 CCOC(=O)c1c(oc2ccc(OCC(=O)OC)cc12)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B07 compound treatment 1.0478 0.187 2.2 1.0766 0.182 2.74 3.494 0.994 1210771 ChemDiv3_003901 CC(C)Cn1c(=O)c2cc3c(=O)n(CC(C)C)c(=O)c3c(C(=O)c4ccc(Cl)cc4)c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B08 compound treatment 1.0801 0.22 2.58 1.1396 0.245 3.69 4.4316 0.9846 1511593 ChemDiv3_003902 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B09 compound treatment 1.0401 0.18 2.11 1.0672 0.173 2.6 3.3306 0.9945 1487762 ChemDiv3_003903 O=S(=O)(NCCC1(CC2CC3CC(C2)C1)C3)c4cccc5nsnc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B10 compound treatment 1.0402 0.18 2.11 1.0736 0.179 2.7 3.3992 0.9925 3023874 ChemDiv3_003904 COc1cc(/C=C\2/C(=N)N3C=CSC3=NC2=O)cc(OC)c1OCCOc4ccc(C)c(C)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B11 compound treatment 1.0214 0.161 1.89 1.0135 0.119 1.79 2.6037 0.9997 3119102 ChemDiv3_003905 CN(C)/C=N/c1c(C#N)cnn1c2ncnc3sc4CCCc4c23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B12 compound treatment 0.9827 0.122 1.43 1.0426 0.148 2.23 2.5923 0.9771 3023875 ChemDiv3_003906 COc1ccc2N3C(=NC(=O)C(Cc4ccccc4)C3=O)Sc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B13 compound treatment 0.9981 0.138 1.61 1.0689 0.175 2.63 2.9994 0.9726 1072961 ChemDiv3_003907 O=c1n(Cc2ccccc2)nc(c3ccccc3)c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B14 compound treatment 0.9731 0.113 1.32 1.0212 0.127 1.91 2.2849 0.9837 1739914 ChemDiv3_003908 Clc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2NCCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B15 compound treatment 0.9988 0.138 1.62 1.0041 0.11 1.65 2.3162 1.0 3023876 ChemDiv3_003909 C(Sc1nc2ccccc2[nH]1)/C=C/c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B16 compound treatment 1.0724 0.212 2.49 1.1507 0.257 3.86 4.4863 0.9774 1325550 ChemDiv3_003910 NC1=C(C#N)C(c2sc3ccccc3c2O1)c4ccccc4OC(=O)c5ccccc5Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B17 compound treatment 0.9567 0.0961 1.13 1.0029 0.109 1.64 1.9548 0.9835 3023877 ChemDiv3_003911 CC(C)OC(=O)C1=c2s/c(=C\c3cccnc3)/c(=O)n2C(=C(C#N)C1c4cccnc4)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B18 compound treatment 0.9699 0.109 1.28 1.0009 0.107 1.61 2.0427 0.9938 3119103 ChemDiv3_003912 COc1ccc(CN2C(=O)CC(Cc3ccc(C)cc3)C2=O)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B19 compound treatment 1.0138 0.153 1.8 1.0202 0.126 1.9 2.6118 0.9997 1408601 ChemDiv3_003913 COc1ccc(CCNc2ncnc3sc4CCCCc4c23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B20 compound treatment 0.9611 0.101 1.18 0.9665 0.0723 1.09 1.6038 0.9992 3023878 ChemDiv3_003914 N=C1NC(=O)/C(=C\c2cc3ccccc3nc2N4CCCCC4)/S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B21 compound treatment 0.9385 0.0779 0.91 0.9828 0.0887 1.33 1.5894 0.983 1543973 ChemDiv3_003915 COc1ccc2CNCCc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B22 compound treatment 0.9391 0.0786 0.92 0.9297 0.0355 0.53 1.0298 0.9663 3119104 ChemDiv3_003916 CC1CCN(CN2CC(COc3ccccc3C)OC2=O)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B23 mock treatment 0.909 0.0484 0.57 0.9 0.00589 0.09 0.4645 0.8076 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 B24 mock treatment 0.9166 0.056 0.66 0.9439 0.0498 0.75 0.9939 0.9979 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C01 compound treatment 0.9909 0.13 1.53 1.0594 0.165 2.49 2.8392 0.9728 3119105 ChemDiv3_003917 COC(=O)C1=CN(C=C(C1c2ccsc2)C(=O)OC)c3cccc(c3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C02 compound treatment 1.0237 0.163 1.91 1.0468 0.153 2.3 2.9772 0.9959 3023910 ChemDiv3_003918 Cn1c(=O)n(C)c2cc(/C=C/3\C(=O)NC(=S)N(CC=C)C3=O)ccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C03 compound treatment 0.9929 0.132 1.55 1.0597 0.166 2.49 2.858 0.9742 3119106 ChemDiv3_003919 CSC1=N/C(=C\c2ccccc2C)/C(=O)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C04 compound treatment 1.0136 0.153 1.8 1.0397 0.146 2.19 2.8176 0.9952 3119107 ChemDiv3_003920 COc1ccc(CCCc2nnc(SCC(=O)Nc3cc(F)ccc3C)o2)cc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C05 compound treatment 1.0177 0.157 1.84 1.0381 0.144 2.16 2.8351 0.9968 3023911 ChemDiv3_003921 C=CCN1C(=O)/C(=C/2\S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)/c5ccccc15 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C06 compound treatment 1.0706 0.21 2.47 1.0932 0.199 2.99 3.8601 0.9954 1871099 ChemDiv3_003922 Cc1cccc(c1)N2C(=O)CC(Sc3nccc(C)n3)C2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C07 compound treatment 1.0687 0.208 2.44 1.0432 0.149 2.24 3.312 0.9991 3023912 ChemDiv3_003923 CSC1=N/C(=C\C=C\c2cccs2)/C(=O)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C08 compound treatment 1.036 0.175 2.06 1.0494 0.155 2.34 3.1075 0.998 1871152 ChemDiv3_003924 O=C(Cc1cccs1)N2c3ccccc3Sc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C09 compound treatment 1.0585 0.198 2.32 1.0678 0.174 2.61 3.4898 0.9983 3023913 ChemDiv3_003925 CCSC1=N/C(=C\c2ccc(C)s2)/C(=O)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C10 compound treatment 1.1898 0.329 3.86 1.0936 0.199 3.0 4.854 0.9922 3119108 ChemDiv3_003926 CCCN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C(=C(C#N)C1=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C11 compound treatment 1.0992 0.239 2.8 1.0955 0.201 3.03 4.1215 0.9992 3023914 ChemDiv3_003927 N=c1[cH-][n+](CCc2ccccc2)no1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C12 compound treatment 1.0335 0.173 2.03 1.056 0.162 2.43 3.1567 0.9959 1216628 ChemDiv3_003928 CCOc1cc(CN2CCN(CC2)C(=O)COc3ccc(C)cc3)ccc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C13 compound treatment 1.1241 0.264 3.09 1.1458 0.252 3.79 4.8636 0.995 3023915 ChemDiv3_003929 COc1ccc(cc1)c2nnc(Nc3cccc(c3)C(F)(F)F)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C14 compound treatment 0.9792 0.119 1.39 1.0503 0.156 2.35 2.6447 0.9688 3119109 ChemDiv3_003930 COc1cccc(CNCCc2c[nH]c3ccccc23)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C15 compound treatment 1.0563 0.196 2.3 1.0523 0.158 2.38 3.3063 0.9998 1485768 ChemDiv3_003931 CCC(=O)NC(c1ccco1)c2cc(Cl)c3cccnc3c2O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C16 compound treatment 1.0075 0.147 1.73 0.994 0.0999 1.5 2.2819 0.9976 1522564 ChemDiv3_003932 Cc1nc(NCCN2CCOCC2)c3sc4nc5CC(C)(C)OCc5cc4c3n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C17 compound treatment 0.9265 0.0659 0.77 1.0118 0.118 1.77 1.7983 0.9311 3119239 ChemDiv3_003933 COc1ccc(cc1)C2CC(=NN2C(=O)CCN3CCOCC3)c4ccc(Br)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C18 compound treatment 0.9281 0.0676 0.79 0.9689 0.0748 1.12 1.3558 0.9854 1139781 ChemDiv3_003934 CC(C)COC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(Cl)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C19 compound treatment 0.9312 0.0706 0.83 0.9695 0.0754 1.13 1.3875 0.9882 1505314 ChemDiv3_003935 O=S1(=O)CCC(C1)N2C(=S)SC3CS(=O)(=O)C=C32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C20 compound treatment 0.941 0.0804 0.94 0.9679 0.0737 1.11 1.4513 0.9968 1867708 ChemDiv3_003936 COc1cc(COc2ccc3c4CCCc4c(=O)oc3c2)cc(OC)c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C21 compound treatment 0.8907 0.0301 0.35 0.9574 0.0633 0.95 0.9228 0.9092 1172275 ChemDiv3_003937 CC1(CCS(=O)(=O)C1)NC(=S)Nc2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C22 compound treatment 0.9049 0.0443 0.52 0.9329 0.0388 0.58 0.7799 0.9984 1132860 ChemDiv3_003938 CN(C)C(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C23 mock treatment 0.9101 0.0495 0.58 0.941 0.0469 0.7 0.9094 0.9954 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 C24 mock treatment 0.9165 0.0559 0.66 0.9325 0.0383 0.58 0.8714 0.9979 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D01 compound treatment 0.9615 0.101 1.18 1.0213 0.127 1.91 2.1894 0.9735 3023916 ChemDiv3_003939 O=S1(=O)N=C(N(CCC#N)/N=C/c2ccccc2)c3ccccc31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D02 compound treatment 1.0074 0.147 1.72 1.0589 0.165 2.48 2.9703 0.9843 3119240 ChemDiv3_003940 COC(=O)C/1=C(C)NC(=O)\C1=C\c2ccc(CNS(=O)(=O)c3ccc(Cl)cc3)o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D03 compound treatment 0.9998 0.139 1.63 1.0699 0.176 2.64 3.0246 0.9733 3023917 ChemDiv3_003941 CCC(C)N1C(=O)S/C(=C/c2ccc3n(C)c(=O)n(C)c3c2)/C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D04 compound treatment 0.9852 0.125 1.46 1.0288 0.135 2.02 2.4657 0.9872 3119241 ChemDiv3_003942 [O-][n+]1cc(c2ccc(F)cc2)[n+]([O-])c3CCCc31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D05 compound treatment 1.0104 0.15 1.76 1.0369 0.143 2.15 2.7612 0.9951 3119242 ChemDiv3_003943 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3sc4CCCCc4c3C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D06 compound treatment 1.0174 0.157 1.84 1.0561 0.162 2.43 3.0229 0.9905 3023918 ChemDiv3_003944 CCCCc1c(O)nc(SCC(=O)N2CCCCC2)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D07 compound treatment 1.2257 0.365 4.29 1.1228 0.229 3.44 5.4617 0.994 3119243 ChemDiv3_003945 COc1ccccc1CC(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D08 compound treatment 1.1061 0.246 2.88 1.1061 0.212 3.19 4.2914 0.9987 3023919 ChemDiv3_003946 OC(Cn1c2ccccc2c3ccccc13)C[n+]4cccc5cccc(O)c45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D09 compound treatment 1.0772 0.217 2.54 1.0842 0.19 2.86 3.8187 0.9983 3119244 ChemDiv3_003947 Nc1nc(SCC(=O)NCc2ccco2)c(C#N)cc1C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D10 compound treatment 1.0589 0.198 2.33 1.0881 0.194 2.92 3.7086 0.9938 3119245 ChemDiv3_003948 COc1ccccc1N(C(=O)NCc2ccccc2)C3=NCC(C)S3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D11 compound treatment 1.0672 0.207 2.43 1.1031 0.209 3.14 3.9375 0.9918 1494926 ChemDiv3_003949 Cc1ccc(cc1)c2nnc(n3cnc4cc(C)c(C)cc34)c5ccccc25 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D12 compound treatment 1.0413 0.181 2.12 1.1156 0.221 3.33 3.8543 0.9763 1647264 ChemDiv3_003950 CCc1nc2oc(C(=O)c3ccccc3)c(N)c2c4CC(C)(C)OCc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D13 compound treatment 0.9892 0.129 1.51 1.0181 0.124 1.86 2.3852 0.9945 1516394 ChemDiv3_003951 Cc1nc(Oc2ccc(NC(=O)c3ccccc3)cc2)c4c5CCCc5sc4n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D14 compound treatment 1.0036 0.143 1.68 1.0367 0.143 2.14 2.7025 0.9927 1736266 ChemDiv3_003952 CCc1ccc(Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(C)cc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D15 compound treatment 0.9614 0.101 1.18 1.0305 0.136 2.05 2.2874 0.9659 1623664 ChemDiv3_003953 C(N1CCc2ccccc2C1)n3cnc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D16 compound treatment 0.9739 0.113 1.33 0.9901 0.0959 1.44 1.9607 0.9992 1684726 ChemDiv3_003954 COc1ccccc1NC(=O)COc2ccc3oc4CCCCc4c3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D17 compound treatment 0.9857 0.125 1.47 0.9994 0.105 1.58 2.1575 0.9993 1574911 ChemDiv3_003955 NC1=C(C#N)C2(C(=O)N(CC=C)c3ccccc32)c4c(O1)c5ccccc5oc4=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D18 compound treatment 0.9287 0.0682 0.8 0.9779 0.0837 1.26 1.4559 0.9761 1249386 ChemDiv3_003956 O=C1CC(Cc2ccccc2)C(=O)N1c3nccs3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D19 compound treatment 0.9328 0.0722 0.85 0.9446 0.0504 0.76 1.1355 0.9985 1153670 ChemDiv3_003957 Cc1sc2nc3c4ccccc4c(NCC5CCCO5)nn3c(=O)c2c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D20 compound treatment 0.9076 0.0471 0.55 0.9676 0.0734 1.1 1.1714 0.9489 3119246 ChemDiv3_003958 CC(=O)N1C(=N)S/C(=C/c2cc3ccccc3nc2Sc4ccccc4)/C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D21 compound treatment 0.9242 0.0637 0.75 0.9628 0.0687 1.03 1.2587 0.9874 1736305 ChemDiv3_003959 CC(C)COc1ccc2c3CCCCc3c(=O)oc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D22 compound treatment 0.881 0.0205 0.24 0.923 0.0289 0.43 0.477 0.9612 3023957 ChemDiv3_003960 CC1CCN(CN2CC(Cn3c4ccccc4c5ccccc35)OC2=O)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D23 mock treatment 0.8621 0.0015 0.02 0.9026 0.00847 0.13 0.1025 0.7973 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 D24 mock treatment 0.8903 0.0298 0.35 0.95 0.0558 0.84 0.841 0.9245 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E01 compound treatment 0.9663 0.106 1.24 1.0412 0.147 2.21 2.4415 0.9627 3119247 ChemDiv3_003961 COC(=O)CN1C=C(C(C(=C1)C(=O)OC)c2ccc(O)cc2)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E02 compound treatment 0.9623 0.102 1.19 1.031 0.137 2.06 2.3003 0.9665 3119248 ChemDiv3_003962 CCC(C)n1cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E03 compound treatment 1.004 0.143 1.68 1.0244 0.13 1.96 2.5751 0.9972 3023958 ChemDiv3_003963 O=C/1N=C(S\C1=C/c2cccs2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E04 compound treatment 0.9719 0.111 1.31 1.0406 0.146 2.2 2.482 0.969 3023959 ChemDiv3_003964 O=C(CSc1nnc(COc2ccccc2)o1)NCc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E05 compound treatment 1.0208 0.16 1.88 1.057 0.163 2.45 3.0619 0.9915 3119249 ChemDiv3_003965 CN/1C(=N)NC(=O)\C1=C\c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E06 compound treatment 1.0294 0.169 1.98 1.0678 0.174 2.61 3.2486 0.9907 1871115 ChemDiv3_003966 CC(C)(CO)NC(=O)c1sc2ccccc2c1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E07 compound treatment 1.0547 0.194 2.28 1.094 0.2 3.01 3.7369 0.9907 3023960 ChemDiv3_003967 C(Sc1nnc-2c(OC(Nc3ccccc32)/C=C/c4ccco4)n1)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E08 compound treatment 1.1254 0.265 3.11 1.0891 0.195 2.93 4.2705 0.9996 3119250 ChemDiv3_003968 Cc1ccc(SCc2cc(O)nc(SCC(=O)n3c4ccccc4c5ccccc35)n2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E09 compound treatment 1.0639 0.203 2.39 1.0802 0.186 2.8 3.6662 0.9969 3023961 ChemDiv3_003969 CCSC1=N/C(=C\c2cccc(F)c2)/C(=O)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E10 compound treatment 1.0576 0.197 2.31 1.0864 0.192 2.89 3.6795 0.9939 1156555 ChemDiv3_003970 CC1CCN(CC1)C(=O)CNS(=O)(=O)c2ccc(C)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E11 compound treatment 1.0622 0.202 2.37 1.0638 0.17 2.55 3.4777 0.9993 1664682 ChemDiv3_003971 Cc1n[nH]c(C)c1N2C(=O)c3cccc4c(N)ccc(C2=O)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E12 compound treatment 1.0523 0.192 2.25 1.0885 0.194 2.92 3.6573 0.9917 1473240 ChemDiv3_003972 O=C(N1CCN(Cc2cccnc2)CC1)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E13 compound treatment 1.0388 0.178 2.09 1.0917 0.198 2.97 3.5809 0.9853 3119251 ChemDiv3_003973 CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc4OCOc4c3)c5ccccc25 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E14 compound treatment 1.0027 0.142 1.67 1.0336 0.139 2.1 2.662 0.9936 1668191 ChemDiv3_003974 CCOc1ccc(CN(CCc2ccc3OCOc3c2)Cc4ccccc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E15 compound treatment 0.9864 0.126 1.48 1.0304 0.136 2.05 2.4933 0.9871 1243341 ChemDiv3_003975 COc1ccc2cc(C3CC(=NN3C(=O)c4ccco4)c5ccc(OC)c(OC)c5)c(Cl)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E16 compound treatment 1.052 0.191 2.25 1.0426 0.148 2.23 3.1669 1.0 3023962 ChemDiv3_003976 Fc1ccc(Nc2nc3ccccc3nc2Nc4ccc(F)cc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E17 compound treatment 0.9482 0.0876 1.03 0.9788 0.0846 1.27 1.6271 0.9944 1173393 ChemDiv3_003977 CC(C)N(C(=O)Cn1c2ccccc2c3nc4ccccc4nc13)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E18 compound treatment 0.9332 0.0727 0.85 1.0258 0.132 1.98 2.0031 0.9292 3023963 ChemDiv3_003978 OC(C#CCN1CCOCC1)c2cccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E19 compound treatment 0.9112 0.0506 0.59 0.9777 0.0836 1.26 1.3085 0.9414 3119252 ChemDiv3_003979 CCN(CC)C(=S)SC1=CCS(=O)(=O)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E20 compound treatment 0.8884 0.0278 0.33 0.9778 0.0836 1.26 1.1202 0.862 1158512 ChemDiv3_003980 COc1ccc2c(c1)c(=O)oc3cc(OC(C)C)ccc32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E21 compound treatment 0.8904 0.0298 0.35 0.9381 0.0439 0.66 0.7143 0.9559 3119253 ChemDiv3_003981 CC12CS(=O)(=O)CC2SC(=S)N1Cc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E22 compound treatment 0.8576 -0.00293 -0.03 0.9136 0.0195 0.29 0.1826 0.6197 1357925 ChemDiv3_003982 CN(C)C(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E23 mock treatment 0.8506 -0.00994 -0.12 0.9496 0.0554 0.83 0.5068 0.6023 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 E24 mock treatment 0.8651 0.00459 0.05 0.9237 0.0296 0.44 0.3527 0.787 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F01 compound treatment 0.9418 0.0812 0.95 1.0343 0.14 2.11 2.1648 0.9356 3023964 ChemDiv3_003983 CN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C(=C(C#N)C1=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F02 compound treatment 0.9584 0.0978 1.15 1.0228 0.129 1.93 2.1798 0.969 3119382 ChemDiv3_003984 O=C(NC1=NCCS1)c2cc3ccccc3o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F03 compound treatment 0.9296 0.069 0.81 1.0248 0.131 1.96 1.9619 0.9233 1627858 ChemDiv3_003985 CN(C)c1ccc2nc3C(=O)c4ccccc4C(=O)c3nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F04 compound treatment 0.9589 0.0983 1.15 1.0223 0.128 1.93 2.1791 0.9699 3119383 ChemDiv3_003986 CC1=[N+]([O-])C(C)(C)[N+](=C1c2ccc(C)cc2)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F05 compound treatment 1.0021 0.141 1.66 1.0278 0.134 2.01 2.5957 0.9955 3119384 ChemDiv3_003987 COC(=O)c1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F06 compound treatment 1.009 0.148 1.74 1.0229 0.129 1.94 2.6007 0.9986 3023965 ChemDiv3_003988 CC(C)Cc1c(O)nc(SCC(=O)NC(C)(C)C)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F07 compound treatment 1.0463 0.186 2.18 1.0572 0.163 2.45 3.2762 0.9983 3119385 ChemDiv3_003989 Cc1ccccc1OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F08 compound treatment 1.0303 0.17 1.99 1.0608 0.167 2.51 3.1814 0.9935 3023966 ChemDiv3_003990 COC(=O)c1c(C)c(=O)[nH]c2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F09 compound treatment 1.1659 0.305 3.58 1.2163 0.322 4.84 5.9598 0.989 1509397 ChemDiv3_003991 Fc1ccc(cc1)C(=O)Nc2ncnc3sc4CCCCCc4c23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F10 compound treatment 1.0468 0.186 2.19 1.1035 0.209 3.15 3.7716 0.9841 3023967 ChemDiv3_003992 FC(F)(F)C1(N=C(OC(=N1)c2ccccc2)N3CCCCC3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F11 compound treatment 1.0463 0.186 2.18 1.0801 0.186 2.8 3.5185 0.9924 1229183 ChemDiv3_003993 Cc1sc2nc3c4ccccc4c(NCCO)nn3c(=O)c2c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F12 compound treatment 1.0265 0.166 1.95 1.0599 0.166 2.49 3.139 0.9926 1299234 ChemDiv3_003994 COC(=O)c1c(N)n(CCc2ccccc2)c3nc4ccccc4nc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F13 compound treatment 1.0257 0.165 1.94 1.069 0.175 2.63 3.23 0.9887 1319064 ChemDiv3_003995 Cc1ccc(Oc2nnc(c3cccs3)c4ccccc24)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F14 compound treatment 1.0095 0.149 1.75 1.0421 0.148 2.23 2.8098 0.9929 3119386 ChemDiv3_003996 Cc1cccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F15 compound treatment 0.9914 0.131 1.54 1.0294 0.135 2.03 2.5237 0.9904 3023968 ChemDiv3_003997 Cn1nc(CC(=O)Nc2nc(cs2)c3ccccc3)c4ccccc4c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F16 compound treatment 0.9462 0.0857 1.01 1.031 0.137 2.06 2.1657 0.9458 3119387 ChemDiv3_003998 COc1ccc(/N=C/c2c(O)ccc3oc4CCCCc4c23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F17 compound treatment 0.9301 0.0696 0.82 0.9752 0.0811 1.22 1.4394 0.981 1229320 ChemDiv3_003999 CCOC(=O)CN1C(=O)C2(C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OCC)c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F18 compound treatment 0.8997 0.0392 0.46 0.956 0.0618 0.93 0.9826 0.9473 1796400 ChemDiv3_004000 COc1ccc(CCn2cnc3sc4CCCCc4c3c2=N)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F19 compound treatment 0.8641 0.00355 0.04 0.9399 0.0457 0.69 0.5156 0.7486 1598055 ChemDiv3_004001 Cc1cc(C(=O)CSc2nnc3cc(C)c4ccccc4n23)c(C)n1Cc5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F20 compound treatment 0.882 0.0215 0.25 0.9291 0.0349 0.52 0.5495 0.9436 3024019 ChemDiv3_004002 CC(=O)N1C(=N)S/C(=C/c2cc3ccc(C)cc3nc2O)/C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F21 compound treatment 0.8774 0.0168 0.2 0.9508 0.0566 0.85 0.742 0.8487 1409929 ChemDiv3_004003 Cn1nc(C(=O)O)c2ccccc2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F22 compound treatment 0.8565 -0.00409 -0.05 0.9233 0.0291 0.44 0.2756 0.6258 1387840 ChemDiv3_004004 CCOC(=O)Cc1c(C)nc(Cc2ccc(OC(C)C)cc2)nc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F23 mock treatment 0.859 -0.00158 -0.02 0.92 0.0259 0.39 0.2617 0.6725 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 F24 mock treatment 0.8509 -0.00969 -0.11 0.8881 -0.00602 -0.09 -0.1444 -0.9936 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G01 compound treatment 0.8983 0.0378 0.44 0.9833 0.0892 1.34 1.2617 0.8933 3119388 ChemDiv3_004005 COC(=O)C1=CN(C=C(C1c2ccccc2)C(=O)OC)C3CC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G02 compound treatment 0.9666 0.106 1.24 1.0651 0.171 2.57 2.6979 0.9445 3024021 ChemDiv3_004006 Cc1cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c(C)n1c3ccccn3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G03 compound treatment 0.9644 0.104 1.22 1.0099 0.116 1.74 2.0925 0.9848 3119389 ChemDiv3_004007 c1ccc2sc(nc2c1)c3cccc(n3)c4nc5ccccc5s4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G04 compound treatment 0.983 0.122 1.44 1.0235 0.129 1.95 2.3915 0.9889 3119390 ChemDiv3_004008 COc1ccc(Cc2nnc(SCC(=O)Nc3ccc(OC)cc3)o2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G05 compound treatment 0.974 0.113 1.33 1.0093 0.115 1.73 2.166 0.9915 3024022 ChemDiv3_004009 COc1ccc(/C=C/C=N/n2c(SC)nnc2c3ccccc3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G06 compound treatment 1.0092 0.149 1.74 1.0175 0.123 1.86 2.5456 0.9995 1871125 ChemDiv3_004010 Cc1c(C)c2ccccc2n1C(=O)CSc3nc4ccccc4s3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G07 compound treatment 1.0206 0.16 1.88 1.002 0.108 1.62 2.475 0.9973 1673764 ChemDiv3_004011 CC(=O)N1C(Oc2nc(SCC=C)nnc2-c3ccccc13)c4ccc(o4)c5ccc(F)cc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G08 compound treatment 1.0437 0.183 2.15 1.0367 0.143 2.14 3.0356 1.0 3119391 ChemDiv3_004012 COc1ccc(NC(=O)C2CC(=O)N=C(Nc3ccccc3)S2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G09 compound treatment 1.0436 0.183 2.15 1.0546 0.16 2.41 3.2255 0.9983 1613829 ChemDiv3_004013 CCSc1nnc(c(O)n1)c2ccccc2NC(=O)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G10 compound treatment 1.0618 0.201 2.36 1.0422 0.148 2.23 3.2437 0.9996 1558726 ChemDiv3_004014 CC(C)(C)NC(=O)N1c2ccccc2Sc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G11 compound treatment 1.0405 0.18 2.11 1.0761 0.182 2.74 3.4286 0.9918 3119392 ChemDiv3_004015 Cc1nn(C)c(C)c1NC(=O)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G12 compound treatment 1.0283 0.168 1.97 1.0686 0.174 2.62 3.2474 0.99 1465103 ChemDiv3_004016 CCc1ccc(CN2CCN(Cc3cccc(OC)c3)CC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G13 compound treatment 1.0348 0.174 2.05 1.1087 0.214 3.23 3.7273 0.9758 3119393 ChemDiv3_004017 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(F)cc3)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G14 compound treatment 1.0498 0.189 2.22 1.1064 0.212 3.19 3.8274 0.9843 1303056 ChemDiv3_004018 CC(C)(C)NC1=C(N(CC(=O)c2ccccc2)S(=O)(=O)c3ccccc13)C(=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G15 compound treatment 0.9687 0.108 1.27 1.0338 0.14 2.1 2.3823 0.971 1692964 ChemDiv3_004019 CCC(=O)N1N=C(CC1c2cc3cc(OC)ccc3nc2Cl)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G16 compound treatment 0.9684 0.108 1.27 0.9918 0.0976 1.47 1.933 0.9973 1699942 ChemDiv3_004020 Brc1ccc(cc1)C2NC(=O)c3ccccc3O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G17 compound treatment 0.9207 0.0601 0.71 0.9705 0.0764 1.15 1.3111 0.9727 3024023 ChemDiv3_004021 CC(=O)OC1CCS(=O)(=O)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G18 compound treatment 0.9141 0.0536 0.63 0.9666 0.0724 1.09 1.2147 0.9659 3119394 ChemDiv3_004022 CCCc1n[nH]c2OC(=C(C#N)C(CCc3ccccc3)c12)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G19 compound treatment 0.8671 0.00655 0.08 0.9516 0.0574 0.86 0.665 0.7671 3024024 ChemDiv3_004023 CC1(CCS(=O)(=O)C1)NC(=S)NCC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G20 compound treatment 0.8941 0.0335 0.39 0.9488 0.0547 0.82 0.8596 0.9432 1713974 ChemDiv3_004024 Oc1cc(OCC(=O)c2ccccc2)cc3oc(cc(=O)c13)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G21 compound treatment 0.859 -0.00155 -0.02 0.9346 0.0404 0.61 0.417 0.6856 1338699 ChemDiv3_004025 CCCCN(C1CCS(=O)(=O)C1)C(=O)Nc2cccc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G22 compound treatment 0.8344 -0.0261 -0.31 0.9153 0.0212 0.32 0.0082 0.0185 1306939 ChemDiv3_004026 Cc1c(OC(=O)c2ccco2)ccc3c4CCCc4c(=O)oc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G23 mock treatment 0.8289 -0.0317 -0.37 0.9346 0.0404 0.61 0.1671 0.2345 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 G24 mock treatment 0.865 0.00448 0.05 0.8974 0.00329 0.05 0.0722 0.9995 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H01 compound treatment 0.9184 0.0579 0.68 1.0239 0.13 1.95 1.8605 0.9003 3119395 ChemDiv3_004027 CC(C)N1C(=O)S/C(=C/c2ccc(Sc3nc4ccccc4[nH]3)o2)/C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H02 compound treatment 0.9491 0.0886 1.04 1.0085 0.114 1.72 1.9506 0.9709 3024025 ChemDiv3_004028 Cc1c(c2ccco2)[n+]([O-])c(c(C)[n+]1[O-])c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H03 compound treatment 0.9154 0.0548 0.64 0.9884 0.0943 1.42 1.4575 0.9362 3119396 ChemDiv3_004029 C/C(=N\O)/CCc1oc2ccccc2c1c3ccc(C)o3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H04 compound treatment 0.9388 0.0783 0.92 0.9918 0.0977 1.47 1.6881 0.9745 3024026 ChemDiv3_004030 CC1N(O)C(C)(C)[N+](=C1c2ccccc2)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H05 compound treatment 0.951 0.0905 1.06 0.9986 0.104 1.57 1.8616 0.9818 3024027 ChemDiv3_004031 CC(=O)N/C(=C\c1cccs1)/C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H06 compound treatment 1.0017 0.141 1.66 0.9968 0.103 1.54 2.263 0.9994 3119397 ChemDiv3_004032 CCSc1nc(O)c(C(C)CC)c(=O)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H07 compound treatment 1.035 0.174 2.05 1.0184 0.124 1.87 2.7692 0.999 1130593 ChemDiv3_004033 O=C(Cc1ccccc1)Nc2cccc(c2)S(=O)(=O)c3cccc(NC(=O)Cc4ccccc4)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H08 compound treatment 1.0548 0.194 2.28 1.0346 0.14 2.11 3.1053 0.9993 3024028 ChemDiv3_004034 CCOC(=O)c1nn(c(C#N)c1NC(=O)c2nn(CC)cc2Br)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H09 compound treatment 1.0211 0.16 1.88 1.0615 0.167 2.52 3.1118 0.9898 1423488 ChemDiv3_004035 COc1cc2c(cc1NP(=O)(C)Oc3ccccc3)oc4ccccc42 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H10 compound treatment 1.0041 0.143 1.68 1.0654 0.171 2.58 3.0118 0.9788 3024029 ChemDiv3_004036 COc1ccc(Cl)cc1NC2=NCC(C)S2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H11 compound treatment 1.0423 0.182 2.13 1.0857 0.192 2.88 3.5449 0.9891 1247540 ChemDiv3_004037 CC1CCN(CC1)c2nn3c(=O)c4c(C)c(C)sc4nc3c5ccccc25 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H12 compound treatment 1.0425 0.182 2.14 1.0784 0.184 2.77 3.47 0.9917 1685422 ChemDiv3_004038 CCOC(=O)c1c(N)n(C2CCCCC2)c3nc4ccccc4nc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H13 compound treatment 0.987 0.126 1.48 1.0407 0.147 2.2 2.6079 0.9815 1241398 ChemDiv3_004039 C1CCCN(CC1)c2nnc(c3cccs3)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H14 compound treatment 1.0022 0.142 1.66 1.0508 0.157 2.36 2.8416 0.9854 3119548 ChemDiv3_004040 CCc1ccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H15 compound treatment 0.957 0.0965 1.13 1.005 0.111 1.67 1.9799 0.9822 3024030 ChemDiv3_004041 O=C(Oc1ccc(cc1)N(Cc2cccs2)C3=NS(=O)(=O)c4ccccc34)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H16 compound treatment 0.9625 0.102 1.2 0.9749 0.0807 1.21 1.7045 1.0 3119549 ChemDiv3_004042 Oc1ccc2oc3CCCCc3c2c1/C=N/N4CCCCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H17 compound treatment 0.9377 0.0771 0.91 0.9761 0.0819 1.23 1.511 0.9885 1705908 ChemDiv3_004043 CCOC(=O)CN1C(=O)C2(C(=C(N)Oc3[nH]nc(C)c32)C#N)c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H18 compound treatment 0.9002 0.0396 0.46 0.9408 0.0466 0.7 0.8245 0.9801 3024031 ChemDiv3_004044 COc1ccc(CCn2cnc3oc(c(c4ccccc4)c3c2=N)c5ccccc5)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H19 compound treatment 0.8678 0.00728 0.09 0.922 0.0278 0.42 0.3561 0.8344 3119550 ChemDiv3_004045 Cc1nc(SC2CCCCN(C(=O)c3ccc(Cl)cc3)C2=O)c4c5CCCCc5sc4n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H20 compound treatment 0.8559 -0.00461 -0.05 0.9457 0.0516 0.78 0.5103 0.6562 3442340 ChemDiv3_004046 CC(C)CC(Nc1ncnc2sc3CCCc3c12)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H21 compound treatment 0.8419 -0.0187 -0.22 0.9101 0.016 0.24 0.0147 0.0453 3024084 ChemDiv3_004047 COC(=O)/C=c/1\sc2ncnn2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H22 compound treatment 0.8397 -0.0208 -0.24 0.8754 -0.0188 -0.28 -0.3729 -0.9974 1470170 ChemDiv3_004048 Nc1cc(=O)nc(SCC(=O)NCc2ccccc2)n1c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H23 mock treatment 0.8354 -0.0251 -0.3 0.9136 0.0194 0.29 -0.0019 -0.0046 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 H24 mock treatment 0.8612 6.04E-4 0.01 0.8883 -0.00582 -0.09 -0.0569 -0.6477 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I01 compound treatment 0.9478 0.0872 1.02 1.0258 0.132 1.98 2.1239 0.9528 3024085 ChemDiv3_004049 Cc1[n+](CC=C)n(C)c2cc(Cl)c(Cl)cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I02 compound treatment 0.9135 0.053 0.62 0.9917 0.0975 1.47 1.4766 0.9271 3119551 ChemDiv3_004050 COCCn1c(C)cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I03 compound treatment 0.9547 0.0942 1.11 1.015 0.121 1.82 2.0667 0.9716 1185967 ChemDiv3_004051 CCSc1nnc-2c(OC(Nc3ccccc32)c4cc5OCOc5cc4Cl)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I04 compound treatment 0.9124 0.0518 0.61 0.9787 0.0845 1.27 1.3292 0.9431 3119552 ChemDiv3_004052 COc1ccc(Cl)c(NC2=NC(=O)/C(=C\c3cccnc3)/S2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I05 compound treatment 0.9169 0.0564 0.66 0.9809 0.0868 1.3 1.3905 0.9504 1528287 ChemDiv3_004053 CSc1nnc-2c(OC(C)N(C(=O)C)c3ccccc32)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I06 compound treatment 0.9383 0.0777 0.91 0.953 0.0588 0.88 1.2702 0.9999 1788578 ChemDiv3_004054 O=C(CSc1nnc(o1)c2ccccc2)N3c4ccccc4CCc5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I07 compound treatment 0.9587 0.0981 1.15 0.9879 0.0937 1.41 1.8114 0.995 3024086 ChemDiv3_004055 COC(=O)C1=C(C)NC(=S)NC1c2cc3OCOc3cc2Br 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I08 compound treatment 1.0593 0.199 2.33 1.032 0.138 2.07 3.1148 0.9983 3119553 ChemDiv3_004056 FC(F)(F)c1cccc(c1)n2c(=O)oc3ccc(Cl)cc3c2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I09 compound treatment 1.0339 0.173 2.03 1.0404 0.146 2.2 2.9937 0.9992 3119554 ChemDiv3_004057 CCc1ccc2NC(=O)/C(=C/3\S\C(=N/c4cccc(Cl)c4C)\NC3=O)/c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I10 compound treatment 1.0292 0.169 1.98 1.0441 0.15 2.25 2.9937 0.9979 1437793 ChemDiv3_004058 O=C(NCCc1ccccc1)N2c3ccccc3Sc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I11 compound treatment 1.0107 0.15 1.76 1.0705 0.176 2.65 3.1211 0.9803 3119555 ChemDiv3_004059 COC(=O)c1cc2c(C)nn(c3ccccc3)c2s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I12 compound treatment 0.9935 0.133 1.56 1.019 0.125 1.88 2.4311 0.9957 1679546 ChemDiv3_004060 CCc1ccc(CN2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I13 compound treatment 0.9848 0.124 1.46 1.045 0.151 2.27 2.6349 0.9772 3119556 ChemDiv3_004061 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(OC)c3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I14 compound treatment 1.0139 0.153 1.8 1.1186 0.224 3.38 3.6599 0.9567 3024087 ChemDiv3_004062 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I15 compound treatment 0.9595 0.099 1.16 0.9843 0.0902 1.36 1.7799 0.997 1737307 ChemDiv3_004063 O=C(N1N=C(CC1c2ccc3nccnc3c2)c4ccccc4)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I16 compound treatment 0.9361 0.0755 0.89 0.9642 0.07 1.05 1.3712 0.9963 3024088 ChemDiv3_004064 NC(=N)SCC1CN=C(S1)N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I17 compound treatment 0.9214 0.0609 0.71 0.9308 0.0367 0.55 0.8953 0.9918 1449842 ChemDiv3_004065 CNC(=S)NC1CCS(=O)(=O)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I18 compound treatment 0.8766 0.016 0.19 0.9387 0.0445 0.67 0.6064 0.8719 3119557 ChemDiv3_004066 CCCOc1ccc(cc1OCC)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I19 compound treatment 0.8769 0.0163 0.19 0.9194 0.0253 0.38 0.4042 0.9499 3024089 ChemDiv3_004067 CCCC(NC1CCS(=O)(=O)C1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I20 compound treatment 0.8364 -0.0241 -0.28 0.887 -0.00719 -0.11 -0.2766 -0.9129 1874878 ChemDiv3_004068 COc1ccc2c(c1)c(=O)oc3c(C)c(OC(C(=O)O)c4ccccc4)ccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I21 compound treatment 0.8368 -0.0237 -0.28 0.8675 -0.0266 -0.4 -0.4798 -0.9843 1557945 ChemDiv3_004069 CCc1ccccc1NC(=O)CC2CS(=O)(=O)CC2CC(=O)Nc3ccccc3CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I22 compound treatment 0.8149 -0.0457 -0.54 0.8743 -0.0199 -0.3 -0.5904 -0.9617 3024090 ChemDiv3_004070 Cc1cc(OC(=O)c2cccs2)c3c4CCCc4c(=O)oc3c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I23 mock treatment 0.8353 -0.0252 -0.3 0.9029 0.00876 0.13 -0.1163 -0.3587 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 I24 mock treatment 0.8274 -0.0331 -0.39 0.8796 -0.0145 -0.22 -0.4291 -0.9628 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J01 compound treatment 0.8932 0.0327 0.38 1.0089 0.115 1.73 1.4917 0.8436 3024091 ChemDiv3_004071 CC(C)N1C(=O)S/C(=C/c2cc(C)n(c2C)c3ccncc3)/C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J02 compound treatment 0.911 0.0504 0.59 0.996 0.102 1.53 1.5014 0.9144 3119558 ChemDiv3_004072 CC(=O)OC1CCC(OC(=O)C)c2c1[n+]([O-])c(C)c(C)[n+]2[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J03 compound treatment 0.9015 0.041 0.48 1.0201 0.126 1.89 1.6795 0.8594 3024092 ChemDiv3_004073 S=c1cc(oc(c1)c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J04 compound treatment 0.9162 0.0557 0.65 0.9869 0.0928 1.4 1.4488 0.9403 3119559 ChemDiv3_004074 Cc1c(c2ccccc2)[n+]([O-])c(c(C)[n+]1[O-])c3ccc(Br)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J05 compound treatment 0.9525 0.0919 1.08 1.013 0.119 1.79 2.0264 0.9708 1128591 ChemDiv3_004075 COc1ccc(CC(=O)Nc2cccc(c2)c3nc4cc5ccccc5cc4[nH]3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J06 compound treatment 0.9325 0.072 0.84 0.9493 0.0552 0.83 1.184 1.0 1255030 ChemDiv3_004076 COc1ccc(cc1OC)C2C(c3cc(OC)c(OC)cc3C2=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J07 compound treatment 0.9857 0.125 1.47 1.0174 0.123 1.85 2.3494 0.9934 3119560 ChemDiv3_004077 O=C(Nc1cccc(c1)c2nc3ccccc3c(=O)o2)C4CCCCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J08 compound treatment 0.9897 0.129 1.52 1.0415 0.147 2.22 2.6384 0.9829 3024093 ChemDiv3_004078 CCOC(=O)c1nn(c(C(=O)OCC)c1NC(=O)C2CCCCC2)c3ccc(OC)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J09 compound treatment 1.0131 0.153 1.79 1.059 0.165 2.48 3.019 0.9872 1215988 ChemDiv3_004079 OC(=O)c1c2CC(CCc2nc3ccccc13)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J10 compound treatment 0.9886 0.128 1.5 1.0453 0.151 2.27 2.6698 0.9798 3119561 ChemDiv3_004080 CC1CN=C(S1)N(C(=O)Nc2ccccc2)c3cccc(c3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J11 compound treatment 0.9687 0.108 1.27 1.0544 0.16 2.41 2.6021 0.9552 1549011 ChemDiv3_004081 Cc1ccc(cc1)c2nn3c(=O)c4ccccc4nc3c5ccccc25 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J12 compound treatment 0.9689 0.108 1.27 1.0463 0.152 2.29 2.5171 0.9616 1317257 ChemDiv3_004082 CCc1ccc(cc1)n2c(N)c(C(=O)OC)c3nc4ccccc4nc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J13 compound treatment 0.9478 0.0872 1.02 1.0188 0.125 1.87 2.0492 0.9595 3024094 ChemDiv3_004083 O=C(CSc1ncnc2sc(cc12)c3ccccc3)c4ccc5OCCOc5c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J14 compound treatment 0.9383 0.0777 0.91 1.0499 0.156 2.34 2.3014 0.9155 3119562 ChemDiv3_004084 FC(F)(F)c1cccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J15 compound treatment 0.9247 0.0642 0.75 1.0029 0.109 1.64 1.6889 0.938 1305983 ChemDiv3_004085 CCCN1CC=C2C(C1)C3(C(=O)Nc4ccccc43)C(C#N)(C#N)C(=C2C#N)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J16 compound treatment 0.9157 0.0552 0.65 0.9461 0.052 0.78 1.0105 0.9956 1458619 ChemDiv3_004086 CC(C)(C)c1nc2scc(c3ccccc3)c2c(=O)o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J17 compound treatment 0.8799 0.0193 0.23 0.9319 0.0377 0.57 0.5619 0.9191 1274153 ChemDiv3_004087 CCOC(=O)C1=C(N)Oc2c(c(=O)oc3ccccc23)C41C(=O)N(CC(=O)OC)c5ccccc54 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J18 compound treatment 0.8156 -0.045 -0.53 0.9132 0.0191 0.29 -0.1701 -0.2832 1393431 ChemDiv3_004088 CCn1c(=O)c2c(-c3ccccc3CC42CCCCC4)n5c(SCC(=O)N)nnc15 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J19 compound treatment 0.8494 -0.0112 -0.13 0.9384 0.0442 0.67 0.3775 0.5568 3119696 ChemDiv3_004089 CCN(CC)C(=O)O[n+]1cccc(CC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J20 compound treatment 0.896 0.0355 0.42 0.9773 0.0831 1.25 1.1784 0.8944 3119697 ChemDiv3_004090 C=CCN1C(=C(OC(=O)c2ccccc2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J21 compound treatment 0.8573 -0.00321 -0.04 0.884 -0.0102 -0.15 -0.1346 -0.8559 1423420 ChemDiv3_004091 Cc1cc(C)n(n1)c2nnc(C)n2NC(=S)NCC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J22 compound treatment 0.83 -0.0305 -0.36 0.8884 -0.00578 -0.09 -0.3149 -0.8539 3119698 ChemDiv3_004092 COC(=O)/C=C/1\N(C(=NC1=O)Nc2nc(C)cc(C)n2)c3cccc(C)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J23 mock treatment 0.8204 -0.0401 -0.47 0.8798 -0.0144 -0.22 -0.4858 -0.9376 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 J24 mock treatment 0.8541 -0.00647 -0.08 0.8879 -0.00629 -0.09 -0.1206 -0.9941 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K01 compound treatment 0.9064 0.0459 0.54 0.9934 0.0993 1.49 1.4364 0.905 3023297 ChemDiv3_004093 Oc1cc(C2C(=O)c3ccccc3C2=O)c4ccc5ccccc5c4n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K02 compound treatment 0.9035 0.043 0.5 0.9742 0.08 1.2 1.2075 0.9254 3119699 ChemDiv3_004094 COCCn1c(C)cc(C=C2C(=O)N(C)C(=S)N(C)C2=O)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K03 compound treatment 0.8873 0.0267 0.31 0.9593 0.0652 0.98 0.9149 0.8891 1169810 ChemDiv3_004095 CSc1nnc-2c(OC(Nc3ccccc32)c4ccccc4)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K04 compound treatment 1.7536 0.893 10.48 1.1165 0.222 3.34 9.7756 0.8885 3119700 ChemDiv3_004096 OC(=O)c1ccc(cc1)c2ccc(/C=C\3/SC(=NC3=O)Nc4cccc(c4)C(=O)O)o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K05 compound treatment 0.9353 0.0748 0.88 0.9569 0.0627 0.94 1.2876 0.9994 3119701 ChemDiv3_004097 CC/1=NN(C(=O)\C1=C/Nc2cc(C)ccn2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K06 compound treatment 0.9305 0.0699 0.82 0.9789 0.0847 1.27 1.4812 0.9774 1871177 ChemDiv3_004098 COc1ccc(Nc2nc(N)nc(CN3CCCCC3)n2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K07 compound treatment 0.9297 0.0691 0.81 0.9848 0.0906 1.36 1.5374 0.9693 3119702 ChemDiv3_004099 CN/1C(=N)NC(=O)\C1=C\c2ccc(C)s2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K08 compound treatment 0.9488 0.0883 1.04 1.0306 0.136 2.05 2.1835 0.9499 3023298 ChemDiv3_004100 COc1ccc(C=C2C(=O)OC3(CCCCC3)OC2=O)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K09 compound treatment 0.9733 0.113 1.32 1.0219 0.128 1.92 2.2941 0.9835 3119703 ChemDiv3_004101 CCOc1cc(/C=C/2\C(=O)Nc3ccc(Br)cc23)ccc1OCC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K10 compound treatment 0.9625 0.102 1.2 0.9949 0.101 1.51 1.9174 0.9932 1400389 ChemDiv3_004102 CCOC(=O)C1CCN(CC1)C(=O)N2c3ccccc3Sc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K11 compound treatment 0.9642 0.104 1.22 1.0268 0.133 1.99 2.2702 0.9718 1679244 ChemDiv3_004103 Cc1ccc(Nc2nc(C)cc(C)c2C(=O)N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K12 compound treatment 0.9451 0.0846 0.99 1.0107 0.117 1.75 1.9413 0.9637 1721188 ChemDiv3_004104 CCCS(=O)(=O)N1CCN(CC1)C2CCN(CC2)C(=O)OCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K13 compound treatment 0.9973 0.137 1.61 1.1488 0.255 3.83 3.8428 0.9255 1612458 ChemDiv3_004105 CCn1c2ccccc2c3cc(NS(=O)(=O)c4ccccc4)ccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K14 compound treatment 0.9434 0.0829 0.97 1.0613 0.167 2.51 2.4646 0.9146 1300482 ChemDiv3_004106 CN1C(=C(N2CCOCC2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K15 compound treatment 0.8778 0.0172 0.2 0.9902 0.0961 1.44 1.1644 0.7982 3023329 ChemDiv3_004107 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K16 compound treatment 0.9023 0.0418 0.49 0.9414 0.0472 0.71 0.8489 0.9837 3119704 ChemDiv3_004108 NC1(N)OC(CN2C(=O)c3ccccc3C2=O)CS1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K17 compound treatment 0.8716 0.0111 0.13 0.937 0.0428 0.64 0.5475 0.833 1697884 ChemDiv3_004109 CCOC(=O)NC1CS(=O)(=O)C=C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K18 compound treatment 0.8308 -0.0298 -0.35 0.9357 0.0416 0.63 0.1952 0.2724 3119705 ChemDiv3_004110 CCN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4ccc(OC)cc4)C(=O)CC(C)(C)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K19 compound treatment 0.8567 -0.00387 -0.05 0.9121 0.0179 0.27 0.1584 0.5798 1179086 ChemDiv3_004111 O=S1(=O)CCC(C1)NC(=S)N2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K20 compound treatment 0.8318 -0.0288 -0.34 0.8942 2.14E-6 0.0 -0.239 -0.707 3119706 ChemDiv3_004112 CCCN1Cc2cccc(C(=O)N)c2C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K21 compound treatment 0.8515 -0.00902 -0.11 0.8928 -0.00134 -0.02 -0.0891 -0.8273 1541504 ChemDiv3_004113 CC(C)NC(=S)SC1CS(=O)(=O)C=C1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K22 compound treatment 0.8459 -0.0146 -0.17 0.8552 -0.039 -0.59 -0.5355 -0.8773 1280043 ChemDiv3_004114 Cc1cc(=O)oc2cc(OCc3cccc(F)c3)ccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K23 mock treatment 0.8371 -0.0235 -0.28 0.8721 -0.022 -0.33 -0.4288 -0.9958 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 K24 mock treatment 0.8825 0.0219 0.26 0.8743 -0.0198 -0.3 -0.0288 -0.0732 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L01 compound treatment 0.9147 0.0541 0.64 1.024 0.13 1.95 1.8295 0.8912 3119707 ChemDiv3_004115 COCCN1C(=O)N(C(=O)/C(=C\c2cn(CC(=O)OC)c3ccccc23)/C1=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L02 compound treatment 0.9119 0.0514 0.6 0.9997 0.106 1.59 1.5487 0.9121 3023337 ChemDiv3_004116 CC1=[N+]([O-])C(C)(C)C(=[N+]1[O-])c2ccc(C)o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L03 compound treatment 0.9288 0.0683 0.8 1.0457 0.152 2.28 2.1784 0.9016 3119708 ChemDiv3_004117 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)NCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L04 compound treatment 0.9133 0.0528 0.62 0.9857 0.0915 1.38 1.411 0.935 3023341 ChemDiv3_004118 [O-][n+]1cc(c2ccccc2)[n+]([O-])c3CCCCc31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L05 compound treatment 0.9045 0.0439 0.52 0.9908 0.0966 1.45 1.3922 0.9028 3023342 ChemDiv3_004119 CC(C)C(=O)Nc1cccc(c1)c2nc3ccccc3c(=O)o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L06 compound treatment 0.9632 0.103 1.21 1.1044 0.21 3.16 3.0879 0.9126 3119709 ChemDiv3_004120 CCc1ccc(OCCCn2cc(/C=C\3/C(=N)N4C=CSC4=NC3=O)c5ccccc25)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L07 compound treatment 0.9086 0.0481 0.56 1.0008 0.107 1.6 1.5331 0.9017 3023344 ChemDiv3_004121 CCSc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L08 compound treatment 0.9178 0.0572 0.67 1.0043 0.11 1.66 1.6463 0.9211 1713113 ChemDiv3_004122 O=S1(=O)C=C(SCCN2CCOCC2)c3ccccc31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L09 compound treatment 0.9461 0.0856 1.0 0.9897 0.0956 1.44 1.7265 0.9847 3023346 ChemDiv3_004123 CN(C)c1oc(nc1C#N)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L10 compound treatment 0.9111 0.0505 0.59 0.9723 0.0782 1.18 1.2507 0.9498 3119710 ChemDiv3_004124 CCC1(COC(NC(=O)c2ccc(Cl)cc2Cl)(C(F)(F)F)C(F)(F)F)COC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L11 compound treatment 0.9414 0.0808 0.95 1.0225 0.128 1.93 2.0352 0.9465 1380020 ChemDiv3_004125 CCC1CCc2c(C1)sc3ncnc(N4CCOCC4)c23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L12 compound treatment 0.9056 0.0451 0.53 1.0021 0.108 1.62 1.5219 0.8914 1709855 ChemDiv3_004126 CCOc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2Nc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L13 compound treatment 0.9042 0.0436 0.51 1.0019 0.108 1.62 1.5084 0.8873 1688543 ChemDiv3_004127 Cc1cc(C)c(C)c(c1C)S(=O)(=O)N2CCN(CC2)c3ncnc4sc5CCCCc5c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L14 compound treatment 0.8885 0.028 0.33 0.9578 0.0636 0.96 0.9086 0.8984 1554741 ChemDiv3_004128 COc1ccc2n(CCc3ccc(OC)c(OC)c3)c(C)c(C(=O)O)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L15 compound treatment 0.882 0.0215 0.25 0.954 0.0599 0.9 0.815 0.8716 1579821 ChemDiv3_004129 COC(=O)CC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L16 compound treatment 0.8848 0.0242 0.28 0.9837 0.0896 1.35 1.1534 0.838 3119711 ChemDiv3_004130 O/N=C/c1c(O)c(Br)cc2oc3CCCCc3c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L17 compound treatment 0.8639 0.00332 0.04 0.9212 0.027 0.41 0.315 0.7714 1421908 ChemDiv3_004131 O=c1n(CN2CCCCC2)nnc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L18 compound treatment 0.8645 0.00393 0.05 0.9511 0.0569 0.86 0.6381 0.7441 1535030 ChemDiv3_004132 COc1ccc(cc1)C(=O)n2nc3CC(C)(C)OCc3c2c4ccc(OC)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L19 compound treatment 0.8175 -0.043 -0.51 0.9018 0.00769 0.12 -0.2754 -0.5315 3119712 ChemDiv3_004133 Cc1ccc(cc1)S(=O)(=O)N/2C(=O)C(C)(C)S\C2=N/CC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L20 compound treatment 0.8484 -0.0121 -0.14 0.8901 -0.004 -0.06 -0.1433 -0.9266 1346941 ChemDiv3_004134 CN1CCN(Cc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L21 compound treatment 0.8231 -0.0375 -0.44 0.8857 -0.0084 -0.13 -0.4003 -0.8749 3119713 ChemDiv3_004135 Cc1nnc(SCc2cccc(c2)C(=O)c3ccccc3)nc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L22 compound treatment 0.8366 -0.024 -0.28 0.8247 -0.0694 -1.04 -0.9371 -0.8667 3119714 ChemDiv3_004136 CC1CCN(CC1)/C(=N\S(=O)(=O)c2ccc(Br)cc2)/Nc3nc(C)cc(C)n3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L23 mock treatment 0.8228 -0.0378 -0.44 0.8669 -0.0272 -0.41 -0.6028 -0.9992 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 L24 mock treatment 0.8571 -0.00346 -0.04 0.8706 -0.0236 -0.35 -0.2795 -0.7828 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M01 compound treatment 0.9684 0.108 1.27 1.0028 0.109 1.63 2.0509 0.992 3119869 ChemDiv3_004137 CCc1cc(C)cc(OCCn2cc(C=C3C(=O)NC(=O)NC3=O)c4ccccc24)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M02 compound treatment 0.9299 0.0694 0.81 0.9552 0.0611 0.92 1.2253 0.9982 3023448 ChemDiv3_004138 CN1C(=O)C(=Cc2cn(CC=C)c3ccccc23)C(=O)N(C)C1=S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M03 compound treatment 0.9057 0.0451 0.53 0.9668 0.0726 1.09 1.1465 0.9448 3023450 ChemDiv3_004139 CCc1cccc2c1NC(=O)C32OCCO3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M04 compound treatment 0.9538 0.0932 1.09 1.0119 0.118 1.77 2.0264 0.9732 1912757 ChemDiv3_004140 Cc1cc2/C(=C/c3ccco3)/OC(=O)c2c(=O)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M05 compound treatment 0.9108 0.0502 0.59 0.9794 0.0852 1.28 1.323 0.9378 3119870 ChemDiv3_004141 CCSC1=N/C(=C\c2ccc(cc2)C(=O)O)/C(=O)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M06 compound treatment 0.8837 0.0232 0.27 0.9951 0.101 1.52 1.2663 0.8207 3023453 ChemDiv3_004142 O=C(COc1ccccc1)N2CCN=C2c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M07 compound treatment 0.9262 0.0656 0.77 1.0103 0.116 1.75 1.7794 0.9323 1181595 ChemDiv3_004143 CCC(=O)N1C(Oc2nc(SC)nnc2-c3ccccc13)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M08 compound treatment 0.8981 0.0376 0.44 1.02 0.126 1.89 1.6506 0.8491 1618375 ChemDiv3_004144 S=C1NC(C2=C(N1)c3ccccc3CC2)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M09 compound treatment 0.9148 0.0542 0.64 1.0384 0.144 2.17 1.9836 0.8776 3023457 ChemDiv3_004145 CCCCN1C(=O)/C(=C/2\S/C(=N\c3ccc(Cl)cc3)/N(C)C2=O)/c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M10 compound treatment 0.8963 0.0357 0.42 0.9991 0.105 1.58 1.4125 0.865 3119871 ChemDiv3_004146 O=C(NCCCc1ccccc1)N2c3ccccc3Sc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M11 compound treatment 0.9527 0.0922 1.08 1.0348 0.141 2.12 2.2609 0.9515 1406185 ChemDiv3_004147 Cc1cc(C)c2c(N=NN3CCCCCC3)n[nH]c2n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M12 compound treatment 0.858 -0.00252 -0.03 0.9775 0.0833 1.25 0.8653 0.6902 3119872 ChemDiv3_004148 Cc1cc(Br)ccc1NCc2ccc3OCOc3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M13 compound treatment 0.8322 -0.0284 -0.33 0.9653 0.0711 1.07 0.521 0.4651 1438334 ChemDiv3_004149 Brc1ccc2oc(=O)c(cc2c1)C(=O)N3CCCc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M14 compound treatment 0.8462 -0.0144 -0.17 0.9768 0.0826 1.24 0.7591 0.6054 3023462 ChemDiv3_004150 CN1C(=C(Nc2ccccc2C)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M15 compound treatment 0.8184 -0.0422 -0.5 0.9505 0.0563 0.85 0.2489 0.2537 1567678 ChemDiv3_004151 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)S(=O)(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M16 compound treatment 0.8229 -0.0376 -0.44 0.9486 0.0545 0.82 0.2668 0.2866 3023506 ChemDiv3_004152 OC(=O)CP(=S)(c1ccccc1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M17 compound treatment 0.8425 -0.0181 -0.21 0.9575 0.0634 0.95 0.5242 0.5368 1339249 ChemDiv3_004153 CCSC(=S)NC1CCS(=O)(=O)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M18 compound treatment 0.8032 -0.0573 -0.67 0.9274 0.0333 0.5 -0.122 -0.1454 3119873 ChemDiv3_004154 CCN1C2=C(C(C3=C1CCCC3=O)c4cccc(O)c4)C(=O)CCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M19 compound treatment 0.8204 -0.0402 -0.47 0.8858 -0.00833 -0.13 -0.4219 -0.8651 1468946 ChemDiv3_004155 CN(C1CCS(=O)(=O)C1)C(=S)SC2CS(=O)(=O)C=C2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M20 compound treatment 0.8303 -0.0303 -0.36 0.869 -0.0252 -0.38 -0.5187 -0.9995 1541732 ChemDiv3_004156 COC(=O)c1ccc(COc2ccc3c(cc(=O)oc3c2C)c4ccccc4)o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M21 compound treatment 0.817 -0.0436 -0.51 0.8433 -0.0509 -0.77 -0.9028 -0.9808 1306134 ChemDiv3_004157 CN(C1CCCCC1)S(=O)(=O)C2CCS(=O)(=O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M22 compound treatment 0.816 -0.0445 -0.52 0.8467 -0.0475 -0.71 -0.8743 -0.9882 3119874 ChemDiv3_004158 CC1CN(CC(C)O1)C2=NC(=O)/C(=C/c3ccccc3)/S2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M23 mock treatment 0.8312 -0.0294 -0.34 0.8374 -0.0568 -0.85 -0.8473 -0.9204 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 M24 mock treatment 0.8532 -0.00737 -0.09 0.8677 -0.0265 -0.4 -0.3426 -0.8411 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N01 compound treatment 0.9313 0.0707 0.83 1.0115 0.117 1.76 1.8346 0.9408 3023511 ChemDiv3_004159 O=C1S/C(=C\c2ccc(o2)N3CCOCC3)/C(=O)N1c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N02 compound treatment 0.9124 0.0518 0.61 0.9554 0.0612 0.92 1.0812 0.9798 3119875 ChemDiv3_004160 CC1=[N+]([O-])C(C)(C)C(=[N+]1[O-])c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N03 compound treatment 0.8937 0.0331 0.39 0.9742 0.08 1.2 1.1258 0.8903 3023512 ChemDiv3_004161 C1CCC2=C(C1)SC3=C(CCCC3)C2c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N04 compound treatment 0.9093 0.0487 0.57 0.9925 0.0983 1.48 1.4499 0.9146 1863423 ChemDiv3_004162 CSc1cccc(NC(=O)c2cc3c(ccc4ccccc34)o2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N05 compound treatment 0.8569 -0.00365 -0.04 0.9706 0.0764 1.15 0.7825 0.6803 3023514 ChemDiv3_004163 O=C(ON1C(=O)c2ccccc2C1=O)C3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N06 compound treatment 0.8861 0.0255 0.3 0.9904 0.0963 1.45 1.2355 0.8357 1713635 ChemDiv3_004164 COC(=O)C1=C(C)Nc2c(C1c3cccc(OCc4ccccc4)c3)c(=O)n(C)c(=O)n2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N07 compound treatment 0.8791 0.0185 0.22 1.0038 0.11 1.65 1.3202 0.7935 3023519 ChemDiv3_004165 CCCCS(=O)(=O)N=C1NCN(CCO)CN1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N08 compound treatment 0.8839 0.0234 0.27 0.9796 0.0855 1.29 1.1026 0.8391 3119876 ChemDiv3_004166 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4cccs4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N09 compound treatment 0.8847 0.0242 0.28 1.0278 0.134 2.01 1.6221 0.799 3119877 ChemDiv3_004167 CCOC(=O)c1c(NC(=O)CC2S/C(=N\CC)/N(CC)C2=O)sc3CCCCc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N10 compound treatment 0.843 -0.0176 -0.21 0.9815 0.0874 1.31 0.7833 0.5888 3023583 ChemDiv3_004168 COc1ccc(CNC(=N)N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N11 compound treatment 0.8863 0.0257 0.3 0.9737 0.0796 1.2 1.0598 0.8587 1550858 ChemDiv3_004169 CC1CCN(CC1)c2nnc(c3cccs3)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N12 compound treatment 0.851 -0.00959 -0.11 0.9782 0.0841 1.26 0.8144 0.6416 1484112 ChemDiv3_004170 O=S(=O)(Nc1nc2ccccc2nc1NCCC3=CCCCC3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N13 compound treatment 0.837 -0.0235 -0.28 0.922 0.0279 0.42 0.101 0.2013 1570344 ChemDiv3_004171 CCc1nc(n2nnc3cc(C)c(C)cc23)c4c5CCCCc5sc4n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N14 compound treatment 0.8184 -0.0422 -0.5 1.0 0.106 1.59 0.7751 0.4651 1352096 ChemDiv3_004172 CCOC(=O)c1c(C)n(C(C)C)c2ccc(OC(=O)c3ccccc3)cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N15 compound treatment 0.7894 -0.0711 -0.83 0.9467 0.0526 0.79 -0.0312 -0.0271 1652261 ChemDiv3_004173 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C32C(=O)N(CO)c4ccccc43)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N16 compound treatment 0.8169 -0.0437 -0.51 0.9418 0.0477 0.72 0.1446 0.1641 3023589 ChemDiv3_004174 CC(C)(C)c1cc2oc3CCCCc3c2c(/C=N/Cc4ccncc4)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N17 compound treatment 0.7757 -0.0849 -1.0 0.911 0.0169 0.25 -0.525 -0.5108 1176412 ChemDiv3_004175 Cc1onc(c1C(=O)NC(=S)NCc2ccco2)c3ccccc3Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N18 compound treatment 0.8218 -0.0388 -0.46 0.9111 0.0169 0.25 -0.1419 -0.2722 1286690 ChemDiv3_004176 CC1(C)CC(CC(=O)N2CCOCC2)(CCO1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N19 compound treatment 0.8637 0.00319 0.04 0.9492 0.055 0.83 0.6117 0.7383 1350975 ChemDiv3_004177 Cc1nn(C(=O)c2cccnc2)c(c1Sc3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N20 compound treatment 0.8122 -0.0483 -0.57 0.857 -0.0371 -0.56 -0.7961 -1.0 3119878 ChemDiv3_004178 CCCN(CCC)CN1CC(Cn2c3ccccc3c4ccccc24)OC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N21 compound treatment 0.8143 -0.0463 -0.54 0.8329 -0.0612 -0.92 -1.0353 -0.9682 1867988 ChemDiv3_004179 CC1CC(c2ccccc2)c3cc(C)ccc3N1S(=O)(=O)c4cccc(Cl)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N22 compound treatment 0.8137 -0.0469 -0.55 0.836 -0.0582 -0.87 -1.0077 -0.975 3119879 ChemDiv3_004180 Clc1ccc(cc1)C(=O)NC(=N)NCc2ccco2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N23 mock treatment 0.8228 -0.0378 -0.44 0.8204 -0.0738 -1.11 -1.098 -0.9189 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 N24 mock treatment 0.8304 -0.0301 -0.35 0.8534 -0.0408 -0.61 -0.6835 -0.9659 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O01 compound treatment 0.9332 0.0726 0.85 1.0 0.106 1.59 1.7281 0.9572 3023594 ChemDiv3_004181 CSc1nnc(c(O)n1)c2ccccc2N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O02 compound treatment 0.9836 0.123 1.44 1.0097 0.116 1.74 2.2499 0.9957 3119880 ChemDiv3_004182 NC(=O)COc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O03 compound treatment 0.9078 0.0472 0.55 0.9823 0.0881 1.33 1.3294 0.9252 3023659 ChemDiv3_004183 CCc1ccc2NC(=O)/C(=C/3\NC(=S)NC3=O)/c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O04 compound treatment 0.9112 0.0506 0.59 0.9983 0.104 1.57 1.5281 0.9119 1537162 ChemDiv3_004184 COCc1cc(C)nc2sc(C(=O)N)c(N)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O05 compound treatment 0.8816 0.021 0.25 0.9397 0.0455 0.69 0.6589 0.905 3023662 ChemDiv3_004185 COc1cccc(/C=C/2\N=C(SC)SC2=O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O06 compound treatment 0.9224 0.0619 0.73 1.0106 0.116 1.75 1.7521 0.924 3119881 ChemDiv3_004186 COc1cc(OC)cc(c1)C(=O)N2CCN=C2c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O07 compound treatment 0.8977 0.0371 0.44 0.9954 0.101 1.52 1.3847 0.8743 3023663 ChemDiv3_004187 CCN(CC)c1ccc(/C=C/2\N(C)C(=N)NC2=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O08 compound treatment 0.9081 0.0475 0.56 1.0387 0.145 2.17 1.9315 0.8606 3119882 ChemDiv3_004188 CC(O)CN1C(=O)/C(=C/c2ccc(o2)c3ccc(Br)cc3)/C(=C(C#N)C1=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O09 compound treatment 0.898 0.0375 0.44 0.975 0.0808 1.22 1.1704 0.9055 3023665 ChemDiv3_004189 CSC1=N/C(=C\c2ccc(Br)cc2)/C(=O)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O10 compound treatment 0.8428 -0.0178 -0.21 0.9568 0.0627 0.94 0.5187 0.5373 1520777 ChemDiv3_004190 CN1C(=O)C(C2CC1(C)Oc3ccccc23)C(=O)NC(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O11 compound treatment 0.8825 0.022 0.26 0.9654 0.0712 1.07 0.9398 0.8528 1527053 ChemDiv3_004191 O=C(CN1CC(=O)Oc2ccccc12)OCC(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O12 compound treatment 0.8422 -0.0183 -0.21 0.9679 0.0737 1.11 0.6323 0.5597 3120033 ChemDiv3_004192 CCn1c2ccccc2c3cc(CNCCc4ccc(Cl)cc4)ccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O13 compound treatment 0.8114 -0.0491 -0.58 0.9538 0.0597 0.9 0.2272 0.2129 1472912 ChemDiv3_004193 O=C(NC1(CCCCC1)C#N)c2cc3ccccc3oc2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O14 compound treatment 0.8579 -0.00269 -0.03 1.0335 0.139 2.1 1.4597 0.6964 3120034 ChemDiv3_004194 CCCN(CCC)C1=C(N(C)S(=O)(=O)c2ccccc12)C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O15 compound treatment 0.7946 -0.0659 -0.77 0.9897 0.0955 1.44 0.4687 0.2873 3120035 ChemDiv3_004195 CS(=O)(=O)N1N=C(CC1c2cc3ccccc3nc2Cl)c4ccc(Br)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O16 compound treatment 0.7767 -0.0839 -0.98 0.9452 0.051 0.77 -0.1535 -0.1229 1484690 ChemDiv3_004196 OC(=O)CCNc1ncnc2sc3CCCCc3c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O17 compound treatment 0.8185 -0.0421 -0.49 0.9399 0.0457 0.69 0.1368 0.1617 3120036 ChemDiv3_004197 C=CCN1[C@H]2CS(=O)(=O)C[C@H]2NC1=S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O18 compound treatment 0.7786 -0.0819 -0.96 0.914 0.0199 0.3 -0.4684 -0.4651 1564957 ChemDiv3_004198 CCOc1ccc(cc1)C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O19 compound treatment 0.7764 -0.0841 -0.99 0.8737 -0.0205 -0.31 -0.9159 -0.8856 3023723 ChemDiv3_004199 CC1=CS(=O)(=O)CC1Sc2nc3ccccc3[nH]2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O20 compound treatment 0.7973 -0.0633 -0.74 0.8804 -0.0137 -0.21 -0.6708 -0.8706 1479636 ChemDiv3_004200 Cc1oc(cc1COc2ccc3c4CCCCc4c(=O)oc3c2)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O21 compound treatment 0.8341 -0.0264 -0.31 0.8712 -0.023 -0.35 -0.4638 -0.9985 3023725 ChemDiv3_004201 Cc1nc2sc3CCCCc3c2c4nnc(SCC(=O)c5ccccc5)n14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O22 compound treatment 0.8285 -0.032 -0.38 0.8647 -0.0294 -0.44 -0.5787 -0.9968 3120037 ChemDiv3_004202 CC1CCC2(CC1)NN(C(=S)N2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O23 mock treatment 0.829 -0.0315 -0.37 0.8274 -0.0667 -1.0 -0.9712 -0.908 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 O24 mock treatment 0.8388 -0.0217 -0.25 0.8787 -0.0154 -0.23 -0.3441 -0.9989 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P01 compound treatment 0.9213 0.0608 0.71 0.9715 0.0773 1.16 1.3268 0.9724 3120038 ChemDiv3_004203 COCCN1C(=O)N(C(=O)/C(=C\c2cc(C)n(c2C)c3ccncc3)/C1=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P02 compound treatment 0.9021 0.0415 0.49 0.9943 0.1 1.51 1.4091 0.8905 3023728 ChemDiv3_004204 CCc1c(C)[n+]([O-])c2CCCCCc2[n+]1[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P03 compound treatment 0.9017 0.0411 0.48 0.9685 0.0743 1.12 1.1313 0.9295 3023729 ChemDiv3_004205 COC(=O)c1ccc(OCC(O)Cn2c(C)[n+](C)c3ccccc23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P04 compound treatment 0.928 0.0674 0.79 0.957 0.0629 0.95 1.2282 0.9961 3120039 ChemDiv3_004206 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCN(CC3)C(=O)c4ccc(F)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P05 compound treatment 0.8905 0.0299 0.35 0.9921 0.098 1.47 1.2901 0.8517 3023733 ChemDiv3_004207 O=C(ON1C(=O)c2ccccc2C1=O)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P06 compound treatment 0.9022 0.0416 0.49 0.9864 0.0922 1.39 1.3261 0.9019 1192417 ChemDiv3_004208 COc1cc(cc(OC)c1OC)C2C3=C(CCCC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P07 compound treatment 0.8952 0.0347 0.41 0.9721 0.078 1.17 1.1169 0.8998 3120040 ChemDiv3_004209 CC(=O)Nc1ccc(cc1)S(=O)(=O)N=C2NCN(CCOC(=O)c3ccccc3)CN2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P08 compound treatment 0.8773 0.0167 0.2 0.9691 0.075 1.13 0.9361 0.818 3023735 ChemDiv3_004210 COC(=O)c1c(C)nn(c1NC(=O)C(C)Oc2ccc(Cl)cc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P09 compound treatment 0.8796 0.0191 0.22 0.98 0.0859 1.29 1.0715 0.8176 1521251 ChemDiv3_004211 Cc1cc2nnn(c3nc(C)nc4sc5CCCCc5c34)c2cc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P10 compound treatment 0.8817 0.0211 0.25 0.9707 0.0766 1.15 0.9899 0.8402 3023737 ChemDiv3_004212 CSc1nc(C)cc(NC(=O)N)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P11 compound treatment 0.8831 0.0226 0.26 0.9905 0.0964 1.45 1.2121 0.8228 1165643 ChemDiv3_004213 CC(C)(C)c1ccc(cc1)c2cc3ccccn3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P12 compound treatment 0.8756 0.015 0.18 0.9803 0.0861 1.3 1.0405 0.796 1379043 ChemDiv3_004214 Fc1ccccc1Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(Cl)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P13 compound treatment 0.8531 -0.00749 -0.09 0.9359 0.0418 0.63 0.3818 0.6022 3120041 ChemDiv3_004215 Cc1cc(C(=O)CSc2ncnc3sc4CCCCc4c23)c(C)n1Cc5ccco5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P14 compound treatment 0.8671 0.00656 0.08 0.9651 0.0709 1.07 0.8085 0.7562 3024070 ChemDiv3_004216 CN1C(=O)/C(=C/Nc2cccc(Cl)c2)/c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P15 compound treatment 0.8644 0.0038 0.04 0.983 0.0889 1.34 0.9766 0.7303 1257595 ChemDiv3_004217 OC(=O)CSc1nnc-2c(OC3(CCCC3)Nc4ccccc42)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P16 compound treatment 0.8654 0.0048 0.06 0.9734 0.0793 1.19 0.8826 0.7397 3024074 ChemDiv3_004218 CN1C(=O)/C(=C\Nc2cccc(CO)c2)/c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P17 compound treatment 0.8438 -0.0168 -0.2 0.9275 0.0333 0.5 0.2152 0.3999 3120042 ChemDiv3_004219 Cc1ccc(Oc2ncnc3sccc23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P18 compound treatment 0.8464 -0.0142 -0.17 0.919 0.0248 0.37 0.1461 0.3578 3024079 ChemDiv3_004220 CC1=N/C(=C/c2cc3ccccc3nc2Sc4ccc(C)cc4)/C(=O)O1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P19 compound treatment 0.8516 -0.009 -0.11 0.9355 0.0413 0.62 0.3645 0.5785 1244804 ChemDiv3_004221 COc1ccc(cc1OC)C(=O)Nn2c(C)nnc2n3nc(C)cc3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P20 compound treatment 0.7878 -0.0727 -0.85 0.8484 -0.0458 -0.69 -1.0905 -0.9943 3120043 ChemDiv3_004222 CC(C)CN(CC(C)C)CN1CC(COc2ccccc2C)OC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P21 compound treatment 0.8404 -0.0202 -0.24 0.8814 -0.0127 -0.19 -0.3029 -0.9945 3023284 ChemDiv3_004223 COC(=O)C1=CN(C=C(C1c2cccc(OC)c2)C(=O)OC)C3(CC4CC5CC(C4)C3)C5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P22 compound treatment 0.8164 -0.0442 -0.52 0.8759 -0.0182 -0.27 -0.5605 -0.9554 1820755 ChemDiv3_004224 O=C(CSc1nnnn1c2ccccc2)N3c4ccccc4CCc5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P23 mock treatment 0.8506 -0.00991 -0.12 0.8792 -0.015 -0.23 -0.2418 -0.9526 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2012 P24 mock treatment 0.8349 -0.0257 -0.3 0.8507 -0.0434 -0.65 -0.6749 -0.9382 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A01 compound treatment 0.9031 0.0166 0.19 0.9498 0.0391 0.59 0.5534 0.8934 3027680 ChemDiv3_007041 FC(F)(F)c1cc(nc(SCCCC(=O)NC2CCCC2)n1)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A02 compound treatment 0.9932 0.107 1.25 0.9565 0.0458 0.69 1.372 0.9604 3118293 ChemDiv3_007042 CC(C)CCNC(=O)c1c(C)oc2C(=O)c3ccccc3C(=O)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A03 compound treatment 0.9094 0.0228 0.27 0.9251 0.0144 0.22 0.3422 0.9942 1788862 ChemDiv3_007043 O=C(Nc1cccnc1)c2nc3ncccn3n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A04 compound treatment 0.9388 0.0522 0.61 1.0011 0.0904 1.36 1.3946 0.9353 1875739 ChemDiv3_007044 OC(=O)c1ccc(NS(=O)(=O)c2cc3C(=O)NC(=O)c4cccc(c2)c43)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A05 compound treatment 1.0219 0.135 1.59 1.0122 0.101 1.53 2.202 0.9998 3027681 ChemDiv3_007045 COC(=O)CSC1=C(C#N)C(=O)NC(S1)/C=C/c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A06 compound treatment 0.8285 -0.0581 -0.68 0.864 -0.0468 -0.7 -0.9792 -0.9999 3118294 ChemDiv3_007046 COc1ccc2[nH]c(SCc3cnc(C)nc3N)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A07 compound treatment 0.8333 -0.0533 -0.63 0.8363 -0.0744 -1.12 -1.2334 -0.9623 3027682 ChemDiv3_007047 CCSC1=C(C#N)C(=O)NC(CO)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A08 compound treatment 0.8196 -0.067 -0.79 0.8221 -0.0887 -1.33 -1.499 -0.9683 3118295 ChemDiv3_007048 Clc1ccc(cc1)C2C3=C(Nc4ccccc4S2(=O)=O)c5ccccc5C3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A09 compound treatment 0.8118 -0.0748 -0.88 0.7797 -0.131 -1.97 -2.0142 -0.9336 3118296 ChemDiv3_007049 CC1(C)OC[C@H](O1)[C@H](O)P(=O)(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A10 compound treatment 0.7761 -0.11 -1.3 0.76 -0.151 -2.27 -2.5193 -0.9649 3027683 ChemDiv3_007050 CC(C)N1CNC(=NC1)Nc2nc3ccccc3o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A11 compound treatment 0.7553 -0.131 -1.54 0.7788 -0.132 -1.98 -2.4926 -0.9922 3118297 ChemDiv3_007051 CCOc1ccc(cc1)C2Nn3c(nnc3SC2C(=O)N4C(C)CCCC4C)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A12 compound treatment 0.7382 -0.148 -1.74 0.8036 -0.107 -1.61 -2.3701 -0.9993 3027684 ChemDiv3_007052 CC(C)CCN1C(=O)c2ccc(cc2C1=O)C3(CC4CC5CC(C4)C3)C5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A13 compound treatment 0.7473 -0.139 -1.63 0.8208 -0.09 -1.35 -2.1123 -0.9956 3118298 ChemDiv3_007053 CCCn1cc(C(CC(=O)O)C(=O)O)c2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A14 compound treatment 0.7581 -0.128 -1.51 0.8241 -0.0866 -1.3 -1.9877 -0.9974 1748461 ChemDiv3_007054 CCOC(=O)c1cnc(SCC(=O)N2CCc3ccccc23)nc1N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A15 compound treatment 0.797 -0.0895 -1.05 0.9934 0.0826 1.24 0.1357 0.0834 3027685 ChemDiv3_007055 COc1ccc(cc1)N2CCc3c2n4c5ccccc5nc4c(C#N)c3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A16 compound treatment 0.8216 -0.065 -0.76 0.8368 -0.0739 -1.11 -1.3249 -0.9831 3118299 ChemDiv3_007056 O=C(CSc1nc2ccccc2nc1N3CCOCC3)NCc4ccc5OCOc5c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A17 compound treatment 0.8196 -0.067 -0.79 0.8571 -0.0536 -0.81 -1.1261 -0.9999 3027686 ChemDiv3_007057 Cn1c(=O)[nH]c(=O)c2n(CC=C)cnc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A18 compound treatment 0.8033 -0.0833 -0.98 0.8587 -0.052 -0.78 -1.2443 -0.9939 3118300 ChemDiv3_007058 Oc1ccc2c(CSc3cccc4cccnc34)cc(=O)oc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A19 compound treatment 0.8645 -0.022 -0.26 0.8678 -0.0429 -0.65 -0.6391 -0.9195 1612422 ChemDiv3_007059 Cc1cc(O)nc(SCc2cn3c(C)cc(C)nc3n2)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A20 compound treatment 0.8308 -0.0557 -0.65 0.8578 -0.053 -0.8 -1.0254 -0.9952 3027740 ChemDiv3_007060 CN(C)C1=NC(N=C(O1)c2ccccc2)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A21 compound treatment 0.8542 -0.0323 -0.38 0.8747 -0.0361 -0.54 -0.6517 -0.9847 3118301 ChemDiv3_007061 S1C(C(=Nc2ccccc12)c3ccccc3)c4nc5ccccc5[nH]4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A22 compound treatment 0.8509 -0.0357 -0.42 0.9024 -0.0083 -0.12 -0.3842 -0.8798 3027741 ChemDiv3_007062 CN(C)C1=NC(c2c(C)nn(c2O1)c3ccccc3)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A23 mock treatment 0.8647 -0.0218 -0.26 0.908 -0.00273 -0.04 -0.2101 -0.8103 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 A24 mock treatment 0.8828 -0.00372 -0.04 0.9254 0.0147 0.22 0.1249 0.556 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B01 compound treatment 1.0369 0.15 1.76 1.003 0.0923 1.39 2.2286 0.9929 1198210 ChemDiv3_007063 Oc1c(ccc2cccnc12)C(N3CCCC3)c4ccncc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B02 compound treatment 0.8966 0.01 0.12 0.9282 0.0175 0.26 0.2692 0.934 1284982 ChemDiv3_007064 OCCNC(=O)c1ccc(cc1)N2C(=O)c3ccccc3C2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B03 compound treatment 0.8805 -0.00607 -0.07 0.8952 -0.0155 -0.23 -0.2154 -0.8827 1247906 ChemDiv3_007065 CC(C)C(c1c(C)[nH]c2ccccc12)c3c(C)[nH]c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B04 compound treatment 0.8607 -0.0259 -0.3 0.883 -0.0277 -0.42 -0.5099 -0.9879 3027742 ChemDiv3_007066 Cc1ccc(NC(=O)CSC(=N)N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B05 compound treatment 0.9605 0.0739 0.87 0.8299 -0.0809 -1.22 -0.2467 -0.1651 3118302 ChemDiv3_007067 COc1ccc2cc(sc(=O)c2c1OC)C(=O)Nc3ccc(O)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B06 compound treatment 0.8141 -0.0724 -0.85 0.8678 -0.043 -0.65 -1.0577 -0.9909 1627380 ChemDiv3_007068 CCN(CC)Cn1cnc2c(SC)ncnc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B07 compound treatment 0.8183 -0.0683 -0.8 0.842 -0.0688 -1.03 -1.2978 -0.992 3118303 ChemDiv3_007069 CC1(C)C2(C)CCC1(C(=O)O)c3nc4ccc5ncccc5c4nc32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B08 compound treatment 0.7993 -0.0872 -1.02 0.8322 -0.0785 -1.18 -1.5591 -0.9975 3027743 ChemDiv3_007070 Clc1ccc(CC2(C(=O)c3ccccc3C2=O)c4ccc(Cl)cc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B09 compound treatment 0.8153 -0.0712 -0.84 0.784 -0.127 -1.91 -1.9388 -0.9315 3118304 ChemDiv3_007071 Cc1c(oc2CC(C)(C)CC(=O)c12)C(=O)N3CCc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B10 compound treatment 0.8047 -0.0819 -0.96 0.7803 -0.13 -1.96 -2.0664 -0.9461 1618272 ChemDiv3_007072 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc3OC(C)(C)Oc3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B11 compound treatment 0.7347 -0.152 -1.78 0.7782 -0.132 -1.99 -2.6687 -0.9984 3027744 ChemDiv3_007073 Cc1ccc(cc1)S(=O)(=O)c2nc(c(NCc3ccco3)s2)S(=O)(=O)c4ccc(C)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B12 compound treatment 0.7694 -0.117 -1.38 0.8366 -0.0742 -1.12 -1.7612 -0.9946 3118305 ChemDiv3_007074 COc1ccc(cc1)C(=O)Nc2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B13 compound treatment 0.7205 -0.166 -1.95 0.8222 -0.0886 -1.33 -2.3201 -0.9828 3118306 ChemDiv3_007075 COc1ccc(cc1)C2C(=C(N)Oc3cc(C)n(CCc4ccc(OC)c(OC)c4)c(=O)c23)C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B14 compound treatment 0.7494 -0.137 -1.61 0.8047 -0.106 -1.6 -2.2659 -1.0 1516177 ChemDiv3_007076 O=C(NCc1ccc2OCOc2c1)c3ccc4c(=O)n(Cc5ccccc5)c(=S)[nH]c4c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B15 compound treatment 0.7745 -0.112 -1.32 0.8485 -0.0622 -0.94 -1.5912 -0.986 3118307 ChemDiv3_007077 CN(C)CCn1c(C)cc2OC(=C(C#N)C(c3ccncc3)c2c1=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B16 compound treatment 0.8188 -0.0677 -0.79 0.8338 -0.0769 -1.16 -1.38 -0.9832 3027745 ChemDiv3_007078 CCOc1ccc(NC(=O)CCNC(=O)c2cn(c3cccc(OC)c3)c(=O)c4ccccc24)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B17 compound treatment 0.7955 -0.0911 -1.07 0.8686 -0.0421 -0.63 -1.2033 -0.9687 3118308 ChemDiv3_007079 Fc1ccc(NP2(=O)COc3ccccc3OC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B18 compound treatment 0.8287 -0.0579 -0.68 0.8549 -0.0558 -0.84 -1.0738 -0.9945 3118309 ChemDiv3_007080 CC1(C)CC(=O)C2=C(C1)N(CCN3CCOCC3)C4=C(C2c5cccc(Cl)c5)C(=O)CC(C)(C)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B19 compound treatment 1.042 0.155 1.82 0.9612 0.0505 0.76 1.8268 0.9245 3027746 ChemDiv3_007081 CC[n+]1c(/C=C/2\SC=CN2C)cc(C)c3cc(OC)c4ccccc4c13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B20 compound treatment 0.8361 -0.0505 -0.59 0.8779 -0.0329 -0.49 -0.7686 -0.9959 3118310 ChemDiv3_007082 CCOC(=O)c1cnc2c(OC)cccc2c1N3CC(C)CC(C)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B21 compound treatment 0.8899 0.00334 0.04 0.9631 0.0524 0.79 0.5845 0.7414 3027747 ChemDiv3_007083 S(c1ccc(/C=N/c2cccc3ccccc23)o1)c4nnnn4c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B22 compound treatment 0.8147 -0.0718 -0.84 0.8661 -0.0446 -0.67 -1.0703 -0.9936 3118432 ChemDiv3_007084 CCOc1ccc2n(CC)/c(=N/C(=O)c3ccc(cc3)S(=O)(=O)N4CCCCC4C)/sc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B23 mock treatment 0.8479 -0.0387 -0.45 0.8491 -0.0616 -0.93 -0.9763 -0.946 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 B24 mock treatment 0.859 -0.0275 -0.32 0.8966 -0.0141 -0.21 -0.3783 -0.9793 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C01 compound treatment 0.9304 0.0438 0.51 0.8957 -0.015 -0.23 0.2045 0.364 3027748 ChemDiv3_007085 FC(F)(F)c1cc(nc(OCC(=O)NCC=C)n1)c2cccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C02 compound treatment 0.9468 0.0602 0.71 0.975 0.0643 0.97 1.1839 0.9881 3118433 ChemDiv3_007086 Cc1oc2C(=O)c3ccccc3C(=O)c2c1C(=O)NCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C03 compound treatment 0.8734 -0.0131 -0.15 0.9168 0.00611 0.09 -0.0439 -0.2446 1788886 ChemDiv3_007087 CCOC(=O)c1c(NC(=O)c2nc3ncccn3n2)sc4CC(CC)CCc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C04 compound treatment 0.8631 -0.0235 -0.28 0.8676 -0.0431 -0.65 -0.6534 -0.9273 3027749 ChemDiv3_007088 OC(=O)CCC(=O)N(Cc1cn(nc1c2cccnc2)c3ccccc3)Cc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C05 compound treatment 0.8385 -0.0481 -0.56 0.8302 -0.0806 -1.21 -1.2558 -0.9395 3118434 ChemDiv3_007089 COC(=O)CSC1=C(C#N)C(=O)NC(S1)c2ccccc2O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C06 compound treatment 0.926 0.0395 0.46 0.8773 -0.0334 -0.5 -0.0281 -0.0411 3027750 ChemDiv3_007090 Cc1ccc(cc1)n2sc3ccccc3c2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C07 compound treatment 0.8801 -0.00647 -0.08 0.8445 -0.0663 -1.0 -0.7582 -0.7588 3118435 ChemDiv3_007091 Oc1ccccc1C2NC(=O)C(=C(SCc3ccccc3)S2)C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C08 compound treatment 0.8104 -0.0761 -0.89 0.8073 -0.103 -1.56 -1.732 -0.9653 3027751 ChemDiv3_007092 Cn1c2NCN(Cc2c(=O)n(C)c1=O)C3CCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C09 compound treatment 0.8084 -0.0782 -0.92 0.8187 -0.092 -1.38 -1.6274 -0.98 1528851 ChemDiv3_007093 CCOc1cccc2cc(c3nc4ccccc4s3)c(=O)oc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C10 compound treatment 0.7539 -0.133 -1.56 0.7987 -0.112 -1.68 -2.2923 -0.9992 3118436 ChemDiv3_007094 C1NC(=NCN1C2CCCCCC2)Nc3nc4ccccc4s3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C11 compound treatment 0.7684 -0.118 -1.39 0.789 -0.122 -1.83 -2.2755 -0.9906 3027752 ChemDiv3_007095 CCN(CC)C(=O)C1Sc2nnc(c3ccccc3)n2NC1c4ccc(C)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C12 compound treatment 0.7499 -0.137 -1.6 0.8148 -0.0959 -1.44 -2.1546 -0.9986 3118437 ChemDiv3_007096 CCC(=O)c1cn(CC(=O)NCCOc2ccc(Cl)cc2)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C13 compound treatment 0.7151 -0.171 -2.01 0.823 -0.0877 -1.32 -2.3556 -0.9791 3118438 ChemDiv3_007097 COc1ccc(cc1)N2C(=O)CC(C2=O)c3cn(Cc4ccccc4)c5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C14 compound treatment 0.8033 -0.0832 -0.98 0.8331 -0.0777 -1.17 -1.5168 -0.9961 3027753 ChemDiv3_007098 Nc1c(C#N)cnc2c(c(COc3ccccc3)nn12)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C15 compound treatment 0.8106 -0.076 -0.89 0.8658 -0.0449 -0.68 -1.1082 -0.9906 3027754 ChemDiv3_007099 CC1=NNC(=O)C1CCc2ccncc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C16 compound treatment 0.8146 -0.072 -0.84 0.8475 -0.0632 -0.95 -1.2691 -0.9983 3118439 ChemDiv3_007100 O=C(CSc1nc2ccccc2nc1N3CCOCC3)N4CCC5(CC4)OCCO5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C17 compound treatment 0.8102 -0.0764 -0.9 0.8789 -0.0318 -0.48 -0.9721 -0.9566 3027755 ChemDiv3_007101 CSc1ccn(Cc2ccc(Cl)cc2)c(=O)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C18 compound treatment 0.7555 -0.131 -1.54 0.8206 -0.0901 -1.36 -2.0464 -0.998 3118440 ChemDiv3_007102 CCCOc1ccc(cc1)/C(=N\O)/C(C)(C)NO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C19 compound treatment 0.8102 -0.0764 -0.9 0.8656 -0.0451 -0.68 -1.1134 -0.9905 3118441 ChemDiv3_007103 CCS(=O)(=O)Nc1cccc(c1)C(=O)CC2(O)C(=O)Nc3ccccc32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C20 compound treatment 0.8139 -0.0727 -0.85 0.8489 -0.0618 -0.93 -1.2609 -0.9991 3026802 ChemDiv3_007104 CC1=CC2=NC(NC(=O)N2C=C1)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C21 compound treatment 0.8124 -0.0742 -0.87 0.8622 -0.0485 -0.73 -1.1314 -0.9961 3026803 ChemDiv3_007105 CCOc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ncnn24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C22 compound treatment 0.81 -0.0766 -0.9 0.8503 -0.0604 -0.91 -1.278 -1.0 3118442 ChemDiv3_007106 CCC1=NC(C2=C(CC(C)(C)CC2=O)N1Cc3ccccc3)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C23 mock treatment 0.861 -0.0255 -0.3 0.8552 -0.0555 -0.83 -0.8018 -0.9043 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 C24 mock treatment 0.8864 -1.27E-4 0.0 0.9011 -0.00962 -0.14 -0.1033 -0.7143 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D01 compound treatment 1.2381 0.352 4.13 0.9474 0.0366 0.55 3.3069 0.7945 1621903 ChemDiv3_007107 CN1CCN(CC1)C(c2c(C)[nH]c3ccccc23)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D02 compound treatment 0.8887 0.00216 0.03 0.8775 -0.0332 -0.5 -0.3351 -0.6703 3026804 ChemDiv3_007108 Cc1ccsc1/C=N/c2ccc(Cl)cc2C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D03 compound treatment 0.8762 -0.0104 -0.12 0.8983 -0.0125 -0.19 -0.2188 -0.9782 1681432 ChemDiv3_007109 Cc1ccc(cc1)C(=O)OC(c2ccccc2)c3nccc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D04 compound treatment 0.8425 -0.044 -0.52 0.8632 -0.0476 -0.72 -0.8714 -0.9872 1346036 ChemDiv3_007110 CCOc1nc(NC2CCCC2)nc(n1)N3CCC(C)CC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D05 compound treatment 0.8704 -0.0161 -0.19 0.8643 -0.0464 -0.7 -0.6271 -0.8675 3118443 ChemDiv3_007111 Cc1sc2N(CN(Cc2c1C)C(C)(C)C)C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D06 compound treatment 0.8039 -0.0827 -0.97 0.8411 -0.0697 -1.05 -1.4267 -0.9993 1643537 ChemDiv3_007112 CCOC(=O)N1N=C(C)CC1(O)c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D07 compound treatment 0.8398 -0.0467 -0.55 0.828 -0.0828 -1.24 -1.2679 -0.9323 3118444 ChemDiv3_007113 O(c1ccc2nccnc2c1)c3ccc4nccnc4c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D08 compound treatment 0.8596 -0.0269 -0.32 0.8507 -0.0601 -0.9 -0.8622 -0.901 3026805 ChemDiv3_007114 CN(C)c1ccc(cc1)c2nc(S)[nH]c(=O)c2C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D09 compound treatment 0.7887 -0.0979 -1.15 0.7997 -0.111 -1.67 -1.9925 -0.9833 3118445 ChemDiv3_007115 CN1CCN(CC1)C(=O)c2oc3CC(C)(C)CC(=O)c3c2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D10 compound treatment 0.76 -0.127 -1.48 0.8171 -0.0936 -1.41 -2.0455 -0.9996 1345726 ChemDiv3_007116 CC(C)(C)N1NC2(CCCCC2)NC1=S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D11 compound treatment 0.9849 0.0984 1.15 0.9965 0.0858 1.29 1.7287 0.9985 1384630 ChemDiv3_007117 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(N2CCOCC2)c3ccc(O)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D12 compound treatment 0.7486 -0.138 -1.62 0.8138 -0.0969 -1.46 -2.1754 -0.9986 3118446 ChemDiv3_007118 Cc1ccccc1NC(=O)c2cnn3c(cc(nc23)c4ccco4)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D13 compound treatment 0.7742 -0.112 -1.32 0.8693 -0.0414 -0.62 -1.3728 -0.9414 1444379 ChemDiv3_007119 COC(=O)C1=C(N)Oc2cc(C)oc(=O)c2C1c3cccnc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D14 compound treatment 0.7815 -0.105 -1.23 0.8275 -0.0832 -1.25 -1.7565 -1.0 1441733 ChemDiv3_007120 COc1ccc(NC(=O)c2ccc3c(=O)n(CCc4ccccc4)c(=S)[nH]c3c2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D15 compound treatment 0.8056 -0.081 -0.95 0.8217 -0.089 -1.34 -1.619 -0.9859 3026806 ChemDiv3_007121 COC(=O)C1=C(N)Oc2cc(C)n(Cc3ccccc3)c(=O)c2C1c4ccncc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D16 compound treatment 0.8598 -0.0267 -0.31 0.8639 -0.0469 -0.7 -0.72 -0.9335 3118447 ChemDiv3_007122 COc1ccccc1n2cc(C(=O)NCC(=O)NCC3COc4ccccc4O3)c5ccccc5c2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D17 compound treatment 0.8128 -0.0737 -0.87 0.8827 -0.0281 -0.42 -0.9103 -0.9456 3026807 ChemDiv3_007123 Clc1ccc(cc1)N2CCN(CC2)P3(=O)COc4ccccc4OC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D18 compound treatment 0.8014 -0.0852 -1.0 0.8488 -0.0619 -0.93 -1.3652 -0.9994 3118448 ChemDiv3_007124 Nc1cc(OC(=O)c2ccccc2)nn1S(=O)(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D19 compound treatment 0.969 0.0824 0.97 1.0059 0.0952 1.43 1.6963 0.9818 3026808 ChemDiv3_007125 COc1ccc2N(C)/C(=C/c3sc4ccccc4[n+]3C)/C=Cc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D20 compound treatment 0.8556 -0.0309 -0.36 0.8886 -0.0221 -0.33 -0.4921 -0.9991 3118449 ChemDiv3_007126 CCOC(=O)c1cnc2ccc(OCC)cc2c1NC(C)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D21 compound treatment 0.8194 -0.0671 -0.79 0.8703 -0.0404 -0.61 -0.9871 -0.9918 1344877 ChemDiv3_007127 O=C(C1CN(C(=O)C1)c2ccccc2)N(Cc3ccccc3)Cc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D22 compound treatment 0.898 0.0115 0.13 0.9454 0.0346 0.52 0.4632 0.8614 3026809 ChemDiv3_007128 CCn1/c(=N/C(=O)c2ccc(cc2)S(=O)(=O)N(C)C)/sc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D23 mock treatment 0.8479 -0.0386 -0.45 0.8856 -0.0251 -0.38 -0.5876 -0.9958 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 D24 mock treatment 0.8631 -0.0235 -0.28 0.874 -0.0367 -0.55 -0.585 -0.9486 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E01 compound treatment 0.943 0.0564 0.66 0.9012 -0.00951 -0.14 0.3673 0.542 3118450 ChemDiv3_007129 CC1CCN(C(C)C1)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccco4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E02 compound treatment 0.9699 0.0833 0.98 1.0063 0.0956 1.44 1.7078 0.9824 3026810 ChemDiv3_007130 Cc1oc2C(=O)c3ccccc3C(=O)c2c1C(=O)NC4CCCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E03 compound treatment 0.9428 0.0562 0.66 0.9079 -0.00284 -0.04 0.4364 0.66 3118451 ChemDiv3_007131 CN(C1CCCCC1)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccco4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E04 compound treatment 0.8341 -0.0524 -0.62 0.8769 -0.0339 -0.51 -0.795 -0.9956 3118452 ChemDiv3_007132 CCc1nc(SCS(=O)(=O)c2ccc(C)cc2)c(C#N)c3CCCCc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E05 compound treatment 0.8681 -0.0184 -0.22 0.8584 -0.0524 -0.79 -0.7098 -0.8691 3026811 ChemDiv3_007133 CCSC1=C(C#N)C(=O)NC(S1)/C=C/c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E06 compound treatment 0.8197 -0.0668 -0.78 0.8771 -0.0336 -0.51 -0.912 -0.9775 3118573 ChemDiv3_007134 OC(=O)c1ccn(Cn2cnc3ccccc23)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E07 compound treatment 0.8283 -0.0583 -0.68 0.8081 -0.103 -1.54 -1.5747 -0.9329 3026812 ChemDiv3_007135 CC1NC(=O)C(=C(SCc2ccccc2)S1)C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E08 compound treatment 0.8392 -0.0473 -0.56 0.8474 -0.0634 -0.95 -1.0666 -0.967 3118574 ChemDiv3_007136 Clc1cccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccccc3)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E09 compound treatment 0.7952 -0.0913 -1.07 0.8241 -0.0866 -1.3 -1.6791 -0.9953 3118575 ChemDiv3_007137 COc1ccc(cc1Cl)C2Nn3c(C)nnc3SC2C(=O)NCc4ccco4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E10 compound treatment 0.7849 -0.102 -1.19 0.8171 -0.0936 -1.41 -1.8388 -0.9966 3026813 ChemDiv3_007138 Clc1ccc(SCc2cc(=O)[nH]c(n2)N3CCN(Cc4ccc5OCOc5c4)CC3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E11 compound treatment 0.7609 -0.126 -1.47 0.8113 -0.0994 -1.49 -2.0995 -1.0 3118576 ChemDiv3_007139 Cc1ccc(cc1)C2Nn3c(nnc3SC2C(=O)NCC4CCCO4)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E12 compound treatment 0.7774 -0.109 -1.28 0.8615 -0.0492 -0.74 -1.4292 -0.9661 3026814 ChemDiv3_007140 CCOC(=O)C(C)N1c2cccc3cccc(c23)S1(=O)=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E13 compound treatment 0.7624 -0.124 -1.46 0.8563 -0.0544 -0.82 -1.6091 -0.9627 3118577 ChemDiv3_007141 CC(C)CN1CC(CC1=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E14 compound treatment 0.8287 -0.0578 -0.68 0.8523 -0.0584 -0.88 -1.1011 -0.9918 3026815 ChemDiv3_007142 Clc1ccc2OCC(=O)N(CC(=O)N3CCCC3)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E15 compound treatment 0.8432 -0.0434 -0.51 0.8625 -0.0483 -0.73 -0.873 -0.9849 1116771 ChemDiv3_007143 OC(=O)Cc1nc2ccccc2[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E16 compound treatment 0.84 -0.0466 -0.55 0.8733 -0.0374 -0.56 -0.7844 -0.9999 3118578 ChemDiv3_007144 Clc1ccc(CCNC(=O)CSc2nc3ccccc3nc2N4CCCC4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E17 compound treatment 0.8375 -0.049 -0.58 0.898 -0.0127 -0.19 -0.5421 -0.8939 1549546 ChemDiv3_007145 Cn1c(NCc2ccco2)nc3n(C)c(=O)n(C)c(=O)c13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E18 compound treatment 0.8193 -0.0672 -0.79 0.8832 -0.0275 -0.41 -0.8504 -0.9545 3118579 ChemDiv3_007146 Cc1ccc2c(C)nc(NC(=N)NS(=O)(=O)c3ccccc3)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E19 compound treatment 0.9579 0.0713 0.84 0.8607 -0.0501 -0.75 0.0594 0.0528 3026816 ChemDiv3_007147 COc1ccc(NC(=O)C(C)C2SC(=O)NC2=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E20 compound treatment 0.7884 -0.0982 -1.15 0.8565 -0.0542 -0.82 -1.3913 -0.9856 3118580 ChemDiv3_007148 Cc1cccc(c1)C2=NC(c3c(N2)n(C)c(=O)n(C)c3=O)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E21 compound treatment 0.8556 -0.031 -0.36 0.9105 -1.83E-4 0.0 -0.2589 -0.7124 3026817 ChemDiv3_007149 CCC1=C(C(c2ccc(Br)cc2)n3ncnc3N1)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E22 compound treatment 0.8402 -0.0463 -0.54 0.8694 -0.0413 -0.62 -0.8242 -0.9978 3118581 ChemDiv3_007150 CC1(C)CC(=O)C2=C(C1)N(Cc3ccco3)C(=O)NC2(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E23 mock treatment 0.8454 -0.0411 -0.48 0.9008 -0.00994 -0.15 -0.4471 -0.8846 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 E24 mock treatment 0.8895 0.0029 0.03 0.9525 0.0418 0.63 0.4687 0.7443 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F01 compound treatment 1.2854 0.399 4.68 1.0517 0.141 2.12 4.8091 0.9358 1293985 ChemDiv3_007151 Oc1c(ccc2cccnc12)C(Nc3cccc(Cl)c3)c4cccnc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F02 compound treatment 0.95 0.0635 0.74 0.8956 -0.0152 -0.23 0.3652 0.4689 3118582 ChemDiv3_007152 CC(NC(=O)CSc1nc2ccc(/N=C/c3ccccc3O)cc2s1)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F03 compound treatment 0.9689 0.0823 0.97 0.8655 -0.0452 -0.68 0.2019 0.1709 1225945 ChemDiv3_007153 OC1(CCN(CC1C(=O)c2ccccc2)C3CCS(=O)(=O)C3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F04 compound treatment 0.8878 0.00124 0.01 0.8745 -0.0362 -0.54 -0.3747 -0.6879 3118583 ChemDiv3_007154 O=C(CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F05 compound treatment 0.8309 -0.0557 -0.65 0.8699 -0.0408 -0.61 -0.8963 -0.9995 3026871 ChemDiv3_007155 CCN(CC)CCN1CN(C(=O)c2ccccc2)c3sc(C)c(C)c3C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F06 compound treatment 0.9603 0.0738 0.87 0.9396 0.0288 0.43 0.919 0.949 3118584 ChemDiv3_007156 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cccs3)/C(=O)N(C2=S)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F07 compound treatment 0.8485 -0.0381 -0.45 0.844 -0.0668 -1.0 -1.0257 -0.9335 1868012 ChemDiv3_007157 CNC(=O)Cc1coc2ccc3ccccc3c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F08 compound treatment 0.8218 -0.0647 -0.76 0.8362 -0.0745 -1.12 -1.3296 -0.982 3118585 ChemDiv3_007158 O=C(CSc1ncccn1)Nc2nccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F09 compound treatment 0.8129 -0.0736 -0.86 0.8438 -0.067 -1.01 -1.323 -0.9971 3026872 ChemDiv3_007159 Cc1ccc2cc3CCN(Cc4ccco4)c3nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F10 compound treatment 0.7936 -0.093 -1.09 0.8127 -0.098 -1.47 -1.8134 -0.989 3118586 ChemDiv3_007160 CCOc1cccc(NC(=O)C2CC(=O)N(/N=C(\C)/c3ccc(Br)s3)C(=N)S2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F11 compound treatment 0.7776 -0.109 -1.28 0.82 -0.0907 -1.36 -1.8682 -0.9995 3118587 ChemDiv3_007161 CCOC(=O)c1ccc2nc(nc(NCCCc3ccccc3)c2c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F12 compound treatment 0.8917 0.00514 0.06 0.8644 -0.0463 -0.7 -0.4495 -0.6434 1635368 ChemDiv3_007162 O=C(NCc1ccccc1)c2ccc3c(=O)n(CCc4ccccc4)c(SCC#N)nc3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F13 compound treatment 0.807 -0.0796 -0.93 0.8653 -0.0454 -0.68 -1.1437 -0.9882 3118588 ChemDiv3_007163 Cc1cc2OC(=C(C#N)C(c3cccc(F)c3)c2c(=O)n1CCN4CCOCC4)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F14 compound treatment 0.8423 -0.0442 -0.52 0.8785 -0.0322 -0.48 -0.7096 -0.9994 1650732 ChemDiv3_007164 COc1ccc(OC)c(c1)n2c(=O)c3ccc(cc3[nH]c2=S)C(=O)NCc4ccc(F)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F15 compound treatment 0.8648 -0.0218 -0.26 0.8646 -0.0461 -0.69 -0.6714 -0.9079 3026873 ChemDiv3_007165 CC(C)c1ccc(cc1)C2C(=C(N)Oc3cc(C)[nH]c(=O)c23)C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F16 compound treatment 0.8466 -0.0399 -0.47 0.8906 -0.0201 -0.3 -0.545 -0.9774 1236286 ChemDiv3_007166 O=C(CCN1C(=O)C2CC=CCC2C1=O)N3CCN(CC3)c4ccccn4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F17 compound treatment 0.8139 -0.0727 -0.85 0.9494 0.0386 0.58 -0.1921 -0.1862 3026874 ChemDiv3_007167 O=P1(COc2ccccc2OC1)Nc3ccccn3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F18 compound treatment 0.8621 -0.0245 -0.29 0.9275 0.0168 0.25 -0.0247 -0.0647 3026875 ChemDiv3_007168 COc1ccc(cc1)S(=O)(=O)n2nc(OC(=O)C(C)(C)C)cc2N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F19 compound treatment 0.8139 -0.0727 -0.85 0.8795 -0.0313 -0.47 -0.9356 -0.9606 3118589 ChemDiv3_007169 COc1cccc(c1)C(=O)NC(NCC2CCCO2)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F20 compound treatment 0.8457 -0.0409 -0.48 0.9238 0.0131 0.2 -0.2003 -0.3864 1723594 ChemDiv3_007170 CCOC(=O)c1cnc2ccc(OCC)cc2c1N(C)Cc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F21 compound treatment 0.8387 -0.0478 -0.56 0.8835 -0.0273 -0.41 -0.687 -0.9881 1579177 ChemDiv3_007171 OP(=O)(CN1CCCCC1)CN2CCCCCC2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F22 compound treatment 0.8675 -0.019 -0.22 0.8963 -0.0145 -0.22 -0.3115 -0.9999 3118590 ChemDiv3_007172 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)/N=c\3/sc4cccc(Cl)c4n3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F23 mock treatment 0.8723 -0.0143 -0.17 0.8889 -0.0218 -0.33 -0.3504 -0.9515 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 F24 mock treatment 0.8834 -0.00318 -0.04 0.9135 0.00281 0.04 0.0035 0.0613 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G01 compound treatment 0.93 0.0435 0.51 0.9156 0.0049 0.07 0.4127 0.8009 3026876 ChemDiv3_007173 COc1ccc(cc1OC)c2cc(nc(SCC(=O)N3CCCCCC3)n2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G02 compound treatment 0.9172 0.0307 0.36 0.8976 -0.0131 -0.2 0.1152 0.2805 3118591 ChemDiv3_007174 Cc1oc2C(=O)c3ccccc3C(=O)c2c1C(=O)NCCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G03 compound treatment 0.9253 0.0387 0.45 0.8887 -0.022 -0.33 0.0874 0.1556 3026877 ChemDiv3_007175 CSc1ccccc1NC(=O)c2cnn3c(cc(nc23)c4ccco4)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G04 compound treatment 0.8754 -0.0111 -0.13 0.8664 -0.0444 -0.67 -0.5642 -0.83 3118592 ChemDiv3_007176 CC1(C)CC(CCO1)N(Cc2cccs2)C(=O)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G05 compound treatment 0.8736 -0.013 -0.15 0.9051 -0.00559 -0.08 -0.1673 -0.9607 3118593 ChemDiv3_007177 CCSC1=C(C#N)C(=O)NC(S1)c2ccco2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G06 compound treatment 0.8167 -0.0698 -0.82 0.8781 -0.0326 -0.49 -0.9261 -0.9699 3026878 ChemDiv3_007178 OC(=O)/C=C/c1ccc2c(onc2c1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G07 compound treatment 0.8211 -0.0655 -0.77 0.8338 -0.0769 -1.16 -1.3615 -0.9803 3118594 ChemDiv3_007179 Cc1csc2nc(=O)c(nn12)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G08 compound treatment 0.7818 -0.105 -1.23 0.8458 -0.065 -0.98 -1.5601 -0.9935 3026879 ChemDiv3_007180 CC(=O)NC1C(=O)Nc2c1cccc2C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G09 compound treatment 0.8003 -0.0863 -1.01 0.8434 -0.0673 -1.01 -1.4318 -1.0 3118595 ChemDiv3_007181 Cc1cccc(NC(=O)C2Sc3nnc(c4ccccc4)n3NC2c5ccccc5)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G10 compound treatment 0.7911 -0.0955 -1.12 0.8168 -0.094 -1.41 -1.7913 -0.9934 3118596 ChemDiv3_007182 CCC(=O)N1CCNC(=O)C1CC(=O)Nc2ccc(C)c(Cl)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G11 compound treatment 0.7822 -0.104 -1.23 0.8202 -0.0905 -1.36 -1.8292 -0.9986 1170868 ChemDiv3_007183 Cn1c(=O)c(Nc2ccccc2)c3-c4ccccc4C(=O)c5cccc1c53 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G12 compound treatment 0.7739 -0.113 -1.32 0.8532 -0.0575 -0.87 -1.5464 -0.9789 3026880 ChemDiv3_007184 CCc1nnc2sc(nn12)c3ccc(N)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G13 compound treatment 0.7953 -0.0912 -1.07 0.8736 -0.0371 -0.56 -1.1519 -0.954 3118721 ChemDiv3_007185 CC(C)(CO)C1(CC2CC3CC(C2)C1)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G14 compound treatment 0.8485 -0.0381 -0.45 0.8836 -0.0271 -0.41 -0.6043 -0.999 3118722 ChemDiv3_007186 Cn1cccc1CNCCc2ccc(F)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G15 compound treatment 0.9573 0.0707 0.83 0.8659 -0.0449 -0.67 0.11 0.1028 3026881 ChemDiv3_007187 Oc1cccnc1NC(=O)CCC2COc3ccccc3O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G16 compound treatment 0.843 -0.0436 -0.51 0.9378 0.027 0.41 -0.0743 -0.1137 3118723 ChemDiv3_007188 CC1CN(CC(C)O1)c2nc3ccccc3nc2SCC(=O)NCc4ccccc4Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G17 compound treatment 0.8467 -0.0398 -0.47 0.9736 0.0628 0.94 0.3377 0.3204 3118724 ChemDiv3_007189 Cc1ccc(NC(=O)c2ccc(CSc3ncnc4[nH]cnc34)cc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G18 compound treatment 0.8208 -0.0657 -0.77 0.9472 0.0365 0.55 -0.1575 -0.1664 3026882 ChemDiv3_007190 CCOC(=O)c1cnc(Nc2nc3ccccc3s2)nc1CSc4ncccn4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G19 compound treatment 0.8205 -0.0661 -0.78 0.8959 -0.0148 -0.22 -0.7056 -0.8748 3118725 ChemDiv3_007191 CC(C1SC(=O)NC1=O)C(=O)Nc2nccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G20 compound treatment 0.8465 -0.04 -0.47 0.9052 -0.00549 -0.08 -0.3905 -0.8189 3026883 ChemDiv3_007192 FC(F)(F)C1(N=C(NC(=N1)c2ccccc2)c3ccccc3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G21 compound treatment 0.8533 -0.0333 -0.39 0.8979 -0.0128 -0.19 -0.4124 -0.9472 3026933 ChemDiv3_007193 NC(=O)c1cc(C(=O)Nc2ccccc2)c(N)nc1SCC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G22 compound treatment 0.8533 -0.0333 -0.39 0.8851 -0.0256 -0.39 -0.5489 -1.0 3118726 ChemDiv3_007194 CC1=C(C#N)C(N=C(N1)C2CCCCC2)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G23 mock treatment 0.879 -0.00755 -0.09 0.9059 -0.00483 -0.07 -0.114 -0.9951 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 G24 mock treatment 0.9127 0.0261 0.31 0.9 -0.0107 -0.16 0.1027 0.2964 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H01 compound treatment 0.9393 0.0527 0.62 0.8866 -0.0241 -0.36 0.1815 0.253 1322971 ChemDiv3_007195 CC(C)c1ccc(cc1)C(Nc2nccs2)c3c(C)[nH]c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H02 compound treatment 0.9076 0.0211 0.25 0.9076 -0.00318 -0.05 0.1411 0.5601 3118727 ChemDiv3_007196 Cc1ccc(cc1)N(CC(=O)NCc2ccco2)S(=O)(=O)c3ccc(C)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H03 compound treatment 0.9363 0.0497 0.58 0.8993 -0.0114 -0.17 0.291 0.4786 1679882 ChemDiv3_007197 Cc1[nH]c2ccccc2c1C(O)c3cccnc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H04 compound treatment 0.8788 -0.0078 -0.09 0.8873 -0.0234 -0.35 -0.3135 -0.8624 3118728 ChemDiv3_007198 COc1ccc(CN/C(=N\c2ccccc2)/SC3CC(=O)NC3=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H05 compound treatment 0.8526 -0.0339 -0.4 0.8758 -0.0349 -0.53 -0.6533 -0.9906 3118729 ChemDiv3_007199 Cc1sc2N(CN(Cc3ccco3)Cc2c1C)C(=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H06 compound treatment 0.8343 -0.0523 -0.61 0.8857 -0.0251 -0.38 -0.7001 -0.9726 3026934 ChemDiv3_007200 CCN1C(=O)/C(=C\C=C\2/Sc3ccc(Cl)cc3N2C)/SC1=S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H07 compound treatment 0.85 -0.0365 -0.43 0.8389 -0.0718 -1.08 -1.0665 -0.9181 3118730 ChemDiv3_007201 Cc1ccc2cc3CCN(c3nc2c1)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H08 compound treatment 0.8223 -0.0642 -0.75 0.8536 -0.0572 -0.86 -1.1408 -0.9979 1574479 ChemDiv3_007202 O=C(CCSc1ccccc1)NC2(CC3CC4CC(C3)C2)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H09 compound treatment 0.8157 -0.0709 -0.83 0.8421 -0.0686 -1.03 -1.3182 -0.9943 3118731 ChemDiv3_007203 Cc1ccc2cc3CCN(c3nc2c1)c4ccc(cc4)C(=O)NCc5ccco5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H10 compound treatment 0.7868 -0.0998 -1.17 0.8477 -0.063 -0.95 -1.4983 -0.9945 1738369 ChemDiv3_007204 CCC(NC(=O)c1cc(OC)c(OC)c(OC)c1)C2(CC3CC4CC(C3)C2)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H11 compound treatment 0.7857 -0.101 -1.18 0.8353 -0.0754 -1.13 -1.6384 -0.9998 3026935 ChemDiv3_007205 CCOC(=O)c1ccc2nc(nc(N3CC(C)OC(C)C3)c2c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H12 compound treatment 0.7964 -0.0902 -1.06 0.8657 -0.045 -0.68 -1.227 -0.9766 1558178 ChemDiv3_007206 CCCCn1c(SCC(=O)OCC)nc2n(CCc3ccccc3)c(=S)sc2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H13 compound treatment 0.809 -0.0776 -0.91 0.8442 -0.0665 -1.0 -1.3514 -0.9989 3118732 ChemDiv3_007207 Cc1cc2OC(=C(C#N)C(c3ccccc3)c2c(=O)n1CCCn4ccnc4)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H14 compound treatment 0.8412 -0.0454 -0.53 0.8843 -0.0264 -0.4 -0.6572 -0.9896 1230528 ChemDiv3_007208 COc1ccc(OC)c(c1)n2c(=O)c3ccc(cc3[nH]c2=S)C(=O)Nc4ccc(C)c(Cl)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H15 compound treatment 0.8535 -0.033 -0.39 0.8819 -0.0288 -0.43 -0.5805 -0.9985 3118733 ChemDiv3_007209 N(c1ccccc1)c2ccc(nn2)n3ccnc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H16 compound treatment 0.8699 -0.0167 -0.2 0.9249 0.0142 0.21 0.0122 0.0424 3026936 ChemDiv3_007210 CC(C)c1ccc(NC(=O)c2coc(=O)c3ccccc23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H17 compound treatment 0.8351 -0.0514 -0.6 0.9654 0.0546 0.82 0.1543 0.1513 3118734 ChemDiv3_007211 CC(C)c1ccc(C)c(OP2(=O)COc3ccccc3OC2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H18 compound treatment 0.8211 -0.0655 -0.77 0.9357 0.025 0.38 -0.2774 -0.3242 3026937 ChemDiv3_007212 CCOC(=O)c1cnc2cc(ccc2c1N(C)Cc3ccccc3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H19 compound treatment 0.8475 -0.0391 -0.46 0.936 0.0252 0.38 -0.0561 -0.0942 3118735 ChemDiv3_007213 Cc1ccc(NC(=O)c2cccc(OC(=S)NCc3ccccc3)c2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H20 compound treatment 0.8698 -0.0168 -0.2 0.931 0.0202 0.3 0.076 0.2097 3118736 ChemDiv3_007214 CCOC(=O)c1cnc2ccc(OCC)cc2c1N3CCN(CC3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H21 compound treatment 0.8728 -0.0137 -0.16 0.9327 0.0219 0.33 0.1191 0.3244 3026938 ChemDiv3_007215 Cc1ccccc1/N=C/c2ccco2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H22 compound treatment 0.8877 0.00119 0.01 0.9507 0.04 0.6 0.435 0.7234 3118737 ChemDiv3_007216 CCn1/c(=N\C(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)/sc4c1ccc5ccccc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H23 mock treatment 0.862 -0.0245 -0.29 0.9019 -0.00888 -0.13 -0.2978 -0.9391 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 H24 mock treatment 0.9009 0.0143 0.17 0.897 -0.0137 -0.21 -0.027 -0.1015 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I01 compound treatment 0.9718 0.0853 1.0 0.944 0.0332 0.5 1.061 0.9485 3026939 ChemDiv3_007217 COc1ccc(cc1OC)c2cc(nc(SCC(=O)N3CCc4ccccc34)n2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I02 compound treatment 0.9439 0.0574 0.67 0.9998 0.0891 1.34 1.4231 0.9494 3118738 ChemDiv3_007218 Cc1oc2C(=O)c3ccccc3C(=O)c2c1C(=O)NCCCn4ccnc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I03 compound treatment 0.9251 0.0385 0.45 0.9166 0.00586 0.09 0.3821 0.8292 3026940 ChemDiv3_007219 Cc1cc(nc(SCc2ccc(o2)C(=O)O)n1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I04 compound treatment 0.8901 0.00359 0.04 0.8895 -0.0212 -0.32 -0.1955 -0.6083 3118739 ChemDiv3_007220 COc1ccc(Br)cc1C(=O)N2Cc3cc(OC)c(OC)cc3C4(CCCC4)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I05 compound treatment 0.8929 0.00638 0.07 0.8905 -0.0203 -0.3 -0.1626 -0.518 3026941 ChemDiv3_007221 CCSC1=C(C#N)C(=O)NC(S1)c2ccc(OC)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I06 compound treatment 0.8479 -0.0386 -0.45 0.8974 -0.0133 -0.2 -0.4622 -0.9325 3118740 ChemDiv3_007222 Clc1ccc(cc1)c2onc3cc(ccc23)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I07 compound treatment 0.7796 -0.107 -1.25 0.8834 -0.0274 -0.41 -1.1785 -0.8923 3026942 ChemDiv3_007223 O=C/1Nc2ccccc2\C1=C\C=C\c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I08 compound treatment 0.8076 -0.079 -0.93 0.853 -0.0577 -0.87 -1.2692 -0.9995 3118741 ChemDiv3_007224 CCCn1c2ccc(C)cc2c3nnc(SCCN4CCOCC4)nc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I09 compound treatment 0.7999 -0.0866 -1.02 0.8722 -0.0385 -0.58 -1.1283 -0.9644 3118742 ChemDiv3_007225 O=C(C1Sc2nnc(c3ccccc3)n2NC1c4ccccc4)N5CCCC5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I10 compound treatment 0.795 -0.0915 -1.07 0.8362 -0.0745 -1.12 -1.5519 -0.9998 3026943 ChemDiv3_007226 CCC(=O)N1C(CC(=O)Nc2ccc(F)cc2)C(=O)NC3CCCCC31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I11 compound treatment 0.878 -0.00857 -0.1 0.912 0.00129 0.02 -0.0574 -0.5599 1866671 ChemDiv3_007227 O=C1c2ccccc2-c3c(NCCc4ccccc4)c(=O)[nH]c5cccc1c35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I12 compound treatment 0.8245 -0.0621 -0.73 0.8537 -0.057 -0.86 -1.1215 -0.9967 3118743 ChemDiv3_007228 COC(=O)C1=C(C)OC(=C(C#N)C1c2cc(C)cc(Cn3ccc(n3)C(F)(F)F)c2C)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I13 compound treatment 0.8228 -0.0637 -0.75 0.8694 -0.0413 -0.62 -0.9685 -0.9957 3026944 ChemDiv3_007229 Nc1cccc(c1)c2ccc(CO)o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I14 compound treatment 0.8278 -0.0587 -0.69 0.8742 -0.0365 -0.55 -0.8755 -0.9937 3118744 ChemDiv3_007230 COc1ccc(CCNC(=O)CSc2nc3ccccc3nc2N4CCCC4)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I15 compound treatment 0.8644 -0.0222 -0.26 0.9087 -0.00201 -0.03 -0.2053 -0.784 3026945 ChemDiv3_007231 NS(=O)(=O)c1ccc(NC(=O)CCC2COc3ccccc3O2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I16 compound treatment 0.8658 -0.0208 -0.24 0.9513 0.0406 0.61 0.259 0.3943 1398603 ChemDiv3_007232 Nc1nonc1N2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I17 compound treatment 0.8359 -0.0507 -0.59 0.9205 0.00979 0.15 -0.3166 -0.5166 3118745 ChemDiv3_007233 COc1ccc(OC)c(NC(=O)c2ccc(CSc3ncnc4[nH]cnc34)cc2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I18 compound treatment 0.8386 -0.048 -0.56 0.9401 0.0294 0.44 -0.0854 -0.1194 3026838 ChemDiv3_007234 CC1CC(=O)c2cnc(nc2C1)N3CCc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I19 compound treatment 0.8311 -0.0555 -0.65 0.9376 0.0269 0.4 -0.1742 -0.2273 3118881 ChemDiv3_007235 COC(=O)c1ccc(CSc2nc(cc(n2)C(F)(F)F)c3cccs3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I20 compound treatment 0.8518 -0.0348 -0.41 0.9049 -0.00583 -0.09 -0.3505 -0.8399 3026840 ChemDiv3_007236 NC1=C(C#N)C(N=C2SCCN21)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I21 compound treatment 0.8758 -0.0107 -0.13 0.9244 0.0137 0.21 0.0563 0.2334 3118882 ChemDiv3_007237 CCc1cc(C(N2CCN(CCO)CC2)c3ccc(Cl)cc3)c(NC(=O)c4ccccc4)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I22 compound treatment 0.9102 0.0237 0.28 0.9134 0.00264 0.04 0.2244 0.8001 3026842 ChemDiv3_007238 CCCCN1C(=NC(C2=C1CC(C)(C)CC2=O)(C(F)(F)F)C(F)(F)F)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I23 mock treatment 0.9053 0.0188 0.22 0.9222 0.0115 0.17 0.2776 0.9926 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 I24 mock treatment 0.9051 0.0185 0.22 0.9272 0.0165 0.25 0.3293 0.9978 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J01 compound treatment 0.9156 0.029 0.34 0.9616 0.0509 0.76 0.7816 0.9335 3026843 ChemDiv3_007239 Oc1ccc(CNc2cccc(c2)C(F)(F)F)c3cccnc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J02 compound treatment 0.9419 0.0553 0.65 0.9384 0.0277 0.42 0.7535 0.9769 3118883 ChemDiv3_007240 Oc1ccc(Cl)cc1/C=N/c2ccc3nc(SCC=C)sc3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J03 compound treatment 1.0223 0.136 1.59 1.0656 0.155 2.33 2.7732 0.9828 1273454 ChemDiv3_007241 COc1ccc(cc1)C(N2CCOCC2)c3ccc4cccnc4c3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J04 compound treatment 0.9091 0.0225 0.26 0.9173 0.00659 0.1 0.2572 0.9103 3026846 ChemDiv3_007242 O=C1CCCC(=O)C1=CNc2cccc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J05 compound treatment 0.8596 -0.0269 -0.32 0.8817 -0.0291 -0.44 -0.5326 -0.9873 3118884 ChemDiv3_007243 Cc1cccc(C)c1OCc2nnc(CCc3ccccc3)o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J06 compound treatment 0.8408 -0.0458 -0.54 0.9116 8.61E-4 0.01 -0.3706 -0.6899 1651075 ChemDiv3_007244 O=C1N(N=C2CCCCCC2)C(Nc3ccccc13)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J07 compound treatment 0.8161 -0.0704 -0.83 0.8808 -0.0299 -0.45 -0.9027 -0.9592 3118885 ChemDiv3_007245 FC(F)(F)c1c(C#N)c(SCc2ccccc2Cl)nc3-c4ccoc4CCc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J08 compound treatment 0.8213 -0.0653 -0.77 0.8474 -0.0634 -0.95 -1.2157 -0.9942 1275637 ChemDiv3_007246 Fc1ccccc1C(=O)NCC(=O)NCc2ccco2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J09 compound treatment 0.8219 -0.0646 -0.76 0.8648 -0.046 -0.69 -1.0252 -0.9989 3026850 ChemDiv3_007247 CC12CNC3(CO)CC2CCC13C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J10 compound treatment 0.8039 -0.0826 -0.97 0.8229 -0.0878 -1.32 -1.6191 -0.9885 3118886 ChemDiv3_007248 O=C(CSc1nnc(c2cccnc2)n1c3ccccc3)NCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J11 compound treatment 0.8069 -0.0797 -0.94 0.8045 -0.106 -1.6 -1.7909 -0.9674 3026852 ChemDiv3_007249 CCOC(=O)c1ccc2nc(nc(N3CCCCC3)c2c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J12 compound treatment 0.8076 -0.0789 -0.93 0.8481 -0.0626 -0.94 -1.3211 -1.0 1632505 ChemDiv3_007250 COc1ccc(NC(=O)c2ccc3c(=O)n(Cc4ccco4)c(=S)[nH]c3c2)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J13 compound treatment 0.8289 -0.0577 -0.68 0.8349 -0.0758 -1.14 -1.2849 -0.9691 3118887 ChemDiv3_007251 Cc1cc2OC(=C(C#N)C(c3cccs3)c2c(=O)n1CC4CCCO4)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J14 compound treatment 0.8223 -0.0642 -0.75 0.8537 -0.057 -0.86 -1.139 -0.9979 1147245 ChemDiv3_007252 COc1ccc(OC)c(c1)n2c(=O)c3ccc(cc3[nH]c2=S)C(=O)N4CCC(CC4)C(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J15 compound treatment 0.8407 -0.0459 -0.54 0.8798 -0.0309 -0.47 -0.7095 -0.9974 3026904 ChemDiv3_007253 Oc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J16 compound treatment 0.8338 -0.0528 -0.62 0.9186 0.00782 0.12 -0.355 -0.5628 3118888 ChemDiv3_007254 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCNC(=O)Cn3cnc4sc5CCCCc5c4c3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J17 compound treatment 0.8287 -0.0578 -0.68 0.922 0.0113 0.17 -0.3599 -0.5144 3026906 ChemDiv3_007255 COC(=O)c1ccc(OP2(=O)COc3ccccc3OC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J18 compound treatment 0.8032 -0.0833 -0.98 0.911 2.86E-4 0.0 -0.6885 -0.704 3026908 ChemDiv3_007256 CCOC(=O)c1cnc2cc(ccc2c1N3CCCCCC3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J19 compound treatment 0.8439 -0.0426 -0.5 0.9282 0.0175 0.26 -0.1676 -0.2967 3118889 ChemDiv3_007257 Oc1cccc(NC=C2C(=O)NC(=S)NC2=O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J20 compound treatment 0.8608 -0.0258 -0.3 0.9189 0.00821 0.12 -0.1266 -0.3874 1384020 ChemDiv3_007258 O=C(N(C1CCCCC1)c2ccccc2)c3cnc4SCCn4c3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J21 compound treatment 0.8769 -0.00968 -0.11 0.9201 0.00936 0.14 0.0192 0.1059 3026911 ChemDiv3_007259 CSc1nc(=O)c(Cc2ccccc2)n[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J22 compound treatment 0.8766 -0.00996 -0.12 0.9179 0.00714 0.11 -0.0068 -0.0427 1518725 ChemDiv3_007260 COc1ccc(cc1)C(=O)NCCn2cc(SC(C)c3ccccc3)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J23 mock treatment 0.927 0.0404 0.47 0.9031 -0.00763 -0.11 0.2542 0.521 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 J24 mock treatment 0.9053 0.0187 0.22 0.9102 -5.59E-4 -0.01 0.1492 0.6795 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K01 compound treatment 0.8999 0.0134 0.16 0.9607 0.05 0.75 0.6422 0.8368 1788828 ChemDiv3_007261 O=C(N1CCc2ccccc2C1)c3nc4ncccn4n3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K02 compound treatment 0.908 0.0214 0.25 0.9327 0.0219 0.33 0.4111 0.9909 3118890 ChemDiv3_007262 CC(=O)Oc1cc2c(C(=O)N3CCCC3)c(C)oc2c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K03 compound treatment 0.9159 0.0293 0.34 0.9465 0.0357 0.54 0.6234 0.9767 3026914 ChemDiv3_007263 CCOC(=O)c1cnn2c(cc(C)nc12)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K04 compound treatment 0.9061 0.0196 0.23 0.9045 -0.00621 -0.09 0.0966 0.3892 3118891 ChemDiv3_007264 Nc1ccc2[nH]c(CCC(=O)O)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K05 compound treatment 0.8162 -0.0703 -0.83 0.8953 -0.0154 -0.23 -0.7476 -0.8718 1026774 ChemDiv3_007265 COc1ccc(cc1)[n+]2cc(O)on2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K06 compound treatment 0.8481 -0.0385 -0.45 0.8628 -0.048 -0.72 -0.8295 -0.9746 3118892 ChemDiv3_007266 Cc1cc2C(=O)C(=C(C(=O)c2cc1C)c3ccccc3)NCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K07 compound treatment 0.8345 -0.052 -0.61 0.8804 -0.0303 -0.46 -0.7544 -0.9897 3026917 ChemDiv3_007267 CCc1cccc2c(c[nH]c12)C(C(=O)c3ccccc3)c4c[nH]c5c(CC)cccc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K08 compound treatment 0.8082 -0.0784 -0.92 0.8895 -0.0212 -0.32 -0.8762 -0.9 3118893 ChemDiv3_007268 OCC1CCCN1CC2CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K09 compound treatment 0.8038 -0.0828 -0.97 0.8681 -0.0427 -0.64 -1.1407 -0.9798 3118894 ChemDiv3_007269 CC(C)CNC(=O)C1Sc2nnc(c3ccccc3)n2NC1c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K10 compound treatment 0.8027 -0.0838 -0.98 0.8522 -0.0585 -0.88 -1.318 -0.9984 3026967 ChemDiv3_007270 Cn1c(=O)n(C)c2nc(ncc2c1=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K11 compound treatment 0.8513 -0.0353 -0.41 0.9202 0.00944 0.14 -0.1924 -0.4395 1131768 ChemDiv3_007271 CC(=O)Nc1ccc(Nc2c3-c4ccccc4C(=O)c5cccc([nH]c2=O)c53)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K12 compound treatment 0.7811 -0.105 -1.24 0.8596 -0.0511 -0.77 -1.418 -0.9737 3026969 ChemDiv3_007272 CCOC(=O)C1=C(CSc2ccc(Cl)cc2)NC(=O)NC1c3cc(C)ccc3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K13 compound treatment 0.8192 -0.0674 -0.79 0.8725 -0.0382 -0.57 -0.9655 -0.9877 3118895 ChemDiv3_007273 O=C1/C(=C/Nc2ccccc2c3nc4ccccc4c(=O)o3)/Sc5ccccc15 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K14 compound treatment 0.8134 -0.0732 -0.86 0.8811 -0.0296 -0.45 -0.9224 -0.9534 3026972 ChemDiv3_007274 O=C(CSc1nc2ccccc2nc1N3CCCC3)Nc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K15 compound treatment 0.8265 -0.0601 -0.7 0.8566 -0.0542 -0.81 -1.0746 -0.9974 3118896 ChemDiv3_007275 NS(=O)(=O)c1ccc(CCNC(=O)CCC2COc3ccccc3O2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K16 compound treatment 0.7978 -0.0887 -1.04 0.9082 -0.00254 -0.04 -0.7633 -0.7325 3118897 ChemDiv3_007276 CCN(CC)CCn1c(=N)n(Cc2ccc(cc2)C(C)(C)C)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K17 compound treatment 0.8116 -0.075 -0.88 0.891 -0.0198 -0.3 -0.8322 -0.8962 1582818 ChemDiv3_007277 CCC(=O)Nc1nonc1c2nc3ccccc3n2CC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K18 compound treatment 0.8365 -0.0501 -0.59 0.9163 0.00556 0.08 -0.3564 -0.6005 3118898 ChemDiv3_007278 Cc1ccc(cc1)S(=O)(=O)NC2=NCN(CCN3CCOCC3)CN2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K19 compound treatment 0.8512 -0.0354 -0.42 0.9227 0.0119 0.18 -0.1667 -0.3687 3026975 ChemDiv3_007279 Cc1ccc(o1)C(O)C(=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K20 compound treatment 0.8401 -0.0465 -0.55 0.9046 -0.0061 -0.09 -0.4506 -0.8145 3118899 ChemDiv3_007280 Cc1ccc(cc1)C2=NC(N=C3SCCN32)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K21 compound treatment 0.864 -0.0225 -0.26 0.9127 0.00194 0.03 -0.1664 -0.6252 3026978 ChemDiv3_007281 CCOC(=O)C1CCN(CC1)C(c2c(NC(=O)C)sc3CCCCc23)c4cccc(Cl)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K22 compound treatment 0.8571 -0.0295 -0.35 0.9143 0.0036 0.05 -0.2064 -0.5894 3118900 ChemDiv3_007282 CCCCN1C(=O)NC(C2=C1CC(C)(C)CC2=O)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K23 mock treatment 0.9204 0.0339 0.4 0.9277 0.0169 0.25 0.4611 0.9768 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 K24 mock treatment 0.9074 0.0209 0.25 0.937 0.0263 0.39 0.4525 0.9737 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L01 compound treatment 1.0924 0.206 2.42 1.0684 0.158 2.37 3.3856 1.0 1446827 ChemDiv3_007283 COc1ccc(cc1)C(N2CCOCC2)c3c(C)[nH]c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L02 compound treatment 0.9358 0.0493 0.58 0.9505 0.0398 0.6 0.8319 0.9999 3026980 ChemDiv3_007284 COc1ccc(/C=N/N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45)cc1Br 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L03 compound treatment 0.9824 0.0959 1.12 0.965 0.0543 0.82 1.3727 0.9876 3119027 ChemDiv3_007285 CC(=O)Nc1cccc(c1)C2=Nc3ccccc3SC(C2)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L04 compound treatment 0.8731 -0.0135 -0.16 0.9166 0.00583 0.09 -0.05 -0.2762 1408100 ChemDiv3_007286 Clc1ccc(cc1)C(=O)c2ccc(cc2)S(=O)(=O)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L05 compound treatment 0.8715 -0.015 -0.18 0.9133 0.00256 0.04 -0.0977 -0.5405 3027023 ChemDiv3_007287 COC(=O)CC1N(CCNC1=O)C(=O)OC(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L06 compound treatment 0.8925 0.00599 0.07 0.9193 0.00858 0.13 0.1409 0.9591 3119028 ChemDiv3_007288 COc1ccc(cc1)/C(=N/N2C(Nc3ccccc3C2=O)c4ccccc4O)/C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L07 compound treatment 0.8339 -0.0527 -0.62 0.9124 0.00162 0.02 -0.4199 -0.6787 3119029 ChemDiv3_007289 COC(=O)c1ccccc1NC(=O)c2ccc(cc2)n3nc(c4CCc5occc5-c43)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L08 compound treatment 0.8383 -0.0482 -0.57 0.8741 -0.0366 -0.55 -0.7899 -0.9999 3027025 ChemDiv3_007290 Cc1cc2nc3s/c(=C/4\C(=O)N(CC(=O)O)c5ccccc45)/c(=O)n3c2cc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L09 compound treatment 0.8124 -0.0742 -0.87 0.924 0.0133 0.2 -0.4742 -0.5307 3119030 ChemDiv3_007291 Cc1ccc(NC(=O)c2ccc(cc2)n3nc(c4CCc5occc5-c43)C(F)(F)F)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L10 compound treatment 0.825 -0.0615 -0.72 0.8589 -0.0519 -0.78 -1.0621 -0.9993 3027027 ChemDiv3_007292 COC(=O)Nc1ccc(cc1)C(=O)NCC2CCCO2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L11 compound treatment 0.8087 -0.0778 -0.91 0.8223 -0.0884 -1.33 -1.5862 -0.9832 3119031 ChemDiv3_007293 CCOC(=O)c1ccc2nc(nc(NCc3ccc(Cl)cc3)c2c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L12 compound treatment 0.8183 -0.0682 -0.8 0.8452 -0.0655 -0.98 -1.2627 -0.9947 1631642 ChemDiv3_007294 CCOC(=O)N1CCN(CC1)C(=O)c2ccc3c(=O)n(CC4CCCO4)c(=S)[nH]c3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L13 compound treatment 0.8173 -0.0692 -0.81 0.8683 -0.0424 -0.64 -1.0255 -0.9928 3119032 ChemDiv3_007295 Cc1cc(O)cc(=O)n1Cc2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L14 compound treatment 0.8763 -0.0102 -0.12 0.9149 0.00419 0.06 -0.0404 -0.2979 1665168 ChemDiv3_007296 COc1ccc(c(OC)c1)n2c(=O)c3ccc(cc3[nH]c2=S)C(=O)NC4CCCC(C)C4C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L15 compound treatment 0.7783 -0.108 -1.27 0.8962 -0.0145 -0.22 -1.0524 -0.8167 3027031 ChemDiv3_007297 C1CCN(CC1)c2ncnc3c4ccccc4oc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L16 compound treatment 0.7969 -0.0896 -1.05 0.8727 -0.038 -0.57 -1.1484 -0.959 1122672 ChemDiv3_007298 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)N(C)C4=C2C(=O)CC(C)(C)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L17 compound treatment 0.7817 -0.105 -1.23 0.9063 -0.00442 -0.07 -0.9169 -0.7442 3027033 ChemDiv3_007299 Clc1ccc2nc(NP3(=O)COc4ccccc4O3)sc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L18 compound treatment 0.817 -0.0695 -0.82 0.9043 -0.00644 -0.1 -0.6454 -0.7856 3119033 ChemDiv3_007300 CCOC(=O)c1cnc2cc(ccc2c1N3CC(C)CC(C)C3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L19 compound treatment 0.8242 -0.0624 -0.73 0.8927 -0.018 -0.27 -0.7089 -0.9084 3027035 ChemDiv3_007301 CCC1(CC)C(=O)N(CC(=O)OC)C(=O)N(C)C1=S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L20 compound treatment 0.8715 -0.015 -0.18 0.9592 0.0485 0.73 0.391 0.521 1630796 ChemDiv3_007302 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N(C)C)nc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L21 compound treatment 0.8562 -0.0303 -0.36 0.8946 -0.0162 -0.24 -0.4236 -0.9829 3119034 ChemDiv3_007303 COC(=O)c1ccc(/C=N/c2ccc3oc(nc3c2)c4ccc(C)cc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L22 compound treatment 0.8423 -0.0442 -0.52 0.9206 0.00991 0.15 -0.2616 -0.4844 1710843 ChemDiv3_007304 COc1ccc(cc1)C(=O)NCCn2cc(SCC(=O)Nc3ccccc3)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L23 mock treatment 0.9078 0.0213 0.25 0.9395 0.0288 0.43 0.4824 0.9659 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 L24 mock treatment 0.8969 0.0104 0.12 0.9231 0.0123 0.19 0.217 0.979 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M01 compound treatment 0.9349 0.0483 0.57 0.9563 0.0455 0.68 0.8851 0.9956 1183622 ChemDiv3_007305 O=C(NCc1ccccc1)c2nc3ncccn3n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M02 compound treatment 0.9096 0.0231 0.27 0.931 0.0202 0.3 0.4065 0.9983 3119035 ChemDiv3_007306 COc1ccc(CNC(=O)c2c(C)oc3c2cc(OC(=O)C)c4ccccc34)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M03 compound treatment 0.9199 0.0333 0.39 0.9155 0.00475 0.07 0.3272 0.8226 3027121 ChemDiv3_007307 COc1cccc(c1)C2CC(n3ncc(C(=O)O)c3N2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M04 compound treatment 0.8971 0.0105 0.12 0.9185 0.00774 0.12 0.1697 0.9996 3119036 ChemDiv3_007308 Cc1ccc2[nH]c(CCCC(=O)O)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M05 compound treatment 0.8616 -0.025 -0.29 0.8991 -0.0116 -0.18 -0.331 -0.9696 3027123 ChemDiv3_007309 CCSC1=C(C#N)C(=O)NC(S1)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M06 compound treatment 0.8461 -0.0405 -0.48 0.8967 -0.014 -0.21 -0.4855 -0.9333 3119037 ChemDiv3_007310 O=C(Nc1ccccc1)C2CC(=O)n3ncnc3N2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M07 compound treatment 0.8472 -0.0393 -0.46 0.8839 -0.0269 -0.4 -0.6118 -0.9978 1057220 ChemDiv3_007311 OC(COc1ccccc1)Cn2ccccc2=N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M08 compound treatment 0.8324 -0.0541 -0.64 0.9014 -0.00934 -0.14 -0.5484 -0.8431 3027125 ChemDiv3_007312 CC(=O)Nc1cccc(c1)c2nn3c(C)nnc3s2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M09 compound treatment 0.7672 -0.119 -1.4 0.8879 -0.0228 -0.34 -1.2329 -0.8549 3119038 ChemDiv3_007313 Fc1ccc(cc1)C2Nn3c(nnc3SC2C(=O)NCc4ccccc4)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M10 compound treatment 0.8293 -0.0572 -0.67 0.8465 -0.0642 -0.97 -1.1577 -0.9842 3027127 ChemDiv3_007314 COC(=O)c1c(C)ncc2COC(C)OCc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M11 compound treatment 0.9383 0.0517 0.61 0.9908 0.0801 1.2 1.281 0.9497 3119039 ChemDiv3_007315 Oc1c(Sc2cccc3cccnc23)cc(NS(=O)(=O)c4ccc(Cl)cc4)c5ccccc15 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M12 compound treatment 0.8154 -0.0712 -0.84 0.8695 -0.0412 -0.62 -1.0289 -0.9892 3027129 ChemDiv3_007316 O=C(CSc1ccccn1)N2CCN(C2)S(=O)(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M13 compound treatment 0.7974 -0.0891 -1.05 0.8616 -0.0492 -0.74 -1.2623 -0.9856 3119040 ChemDiv3_007317 CN(C)CCNC(=O)c1cc2ccccc2oc1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M14 compound treatment 0.8009 -0.0857 -1.01 0.8601 -0.0506 -0.76 -1.2492 -0.9906 3119041 ChemDiv3_007318 CC1CN(CC(C)O1)c2nc3ccccc3nc2SCC(=O)NCCc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M15 compound treatment 0.8135 -0.073 -0.86 0.9037 -0.00699 -0.11 -0.6802 -0.7879 3027131 ChemDiv3_007319 COCCn1c(nc(=S)c2COC(C)(C)Cc21)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M16 compound treatment 0.8014 -0.0851 -1.0 0.857 -0.0537 -0.81 -1.2775 -0.9944 3027133 ChemDiv3_007320 Cn1c(=N)n(CCCOc2ccc(F)cc2)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M17 compound treatment 0.776 -0.111 -1.3 0.851 -0.0597 -0.9 -1.5523 -0.9838 3119042 ChemDiv3_007321 Cc1ccn2cc(cc2c1)c3cccs3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M18 compound treatment 0.8333 -0.0532 -0.62 0.8862 -0.0245 -0.37 -0.7026 -0.9685 3119043 ChemDiv3_007322 Cc1ccc2C(=O)NC(Nc2c1)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M19 compound treatment 0.8126 -0.0739 -0.87 0.8914 -0.0193 -0.29 -0.8187 -0.8949 3027207 ChemDiv3_007323 CCOC(=O)c1ccc(Nc2nnc3n(CC=C)c(=O)c4c(C)c(C)sc4n23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M20 compound treatment 0.8629 -0.0237 -0.28 0.925 0.0143 0.21 -0.0448 -0.1275 3119044 ChemDiv3_007324 CC1=C(C#N)C(N=C(N1)c2ccncc2)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M21 compound treatment 0.8873 7.5E-4 0.01 0.9701 0.0593 0.89 0.6371 0.7141 3027209 ChemDiv3_007325 CC1CCN(CC1)C(=O)c2c(C)oc3C(=O)c4ccccc4C(=O)c23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M22 compound treatment 0.862 -0.0246 -0.29 0.9196 0.00889 0.13 -0.1094 -0.3442 3119045 ChemDiv3_007326 CC1=C(C#N)C(N=C(Cc2ccccc2)N1)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M23 mock treatment 0.8921 0.00554 0.07 0.9359 0.0252 0.38 0.3136 0.8167 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 M24 mock treatment 0.88 -0.00658 -0.08 0.9356 0.0248 0.37 0.2095 0.5494 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N01 compound treatment 0.9815 0.095 1.11 1.0006 0.0899 1.35 1.7442 0.9954 1651520 ChemDiv3_007327 COc1ccc(cc1)C(OC(=O)c2ccccc2)c3nccc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N02 compound treatment 0.9064 0.0199 0.23 0.9356 0.0248 0.37 0.4289 0.9743 1505116 ChemDiv3_007328 Cc1ccc(NC(=O)c2cc(=O)[nH]c(=O)[nH]2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N03 compound treatment 0.9046 0.0181 0.21 0.945 0.0343 0.52 0.5149 0.9229 3119046 ChemDiv3_007329 CC(=O)N1CN(Cc2c3CCCCc3sc12)C4CCS(=O)(=O)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N04 compound treatment 0.8853 -0.00126 -0.01 0.9353 0.0246 0.37 0.2513 0.6784 1135097 ChemDiv3_007330 CCN(CC)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)Oc2ccc(C)c(C)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N05 compound treatment 0.9257 0.0392 0.46 0.9884 0.0777 1.17 1.1513 0.9168 3119047 ChemDiv3_007331 Oc1ccc(NC(=O)CN2CC(=O)Oc3ccccc23)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N06 compound treatment 0.8779 -0.00868 -0.1 0.8834 -0.0274 -0.41 -0.3631 -0.8564 3027214 ChemDiv3_007332 CCOC(=O)C1=C(NC(=S)NC1CC)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N07 compound treatment 0.8726 -0.0139 -0.16 0.8986 -0.0121 -0.18 -0.2441 -0.9985 3119048 ChemDiv3_007333 CC(C)(C)NC(=O)c1ccc(cc1)n2nc(c3CCc4occc4-c32)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N08 compound treatment 0.8261 -0.0604 -0.71 0.9205 0.00974 0.15 -0.398 -0.5494 3119179 ChemDiv3_007334 CCc1nnc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N09 compound treatment 0.8569 -0.0296 -0.35 0.9182 0.00749 0.11 -0.1664 -0.455 3027218 ChemDiv3_007335 OC(=O)c1nn(c-2c1CCc3occc32)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N10 compound treatment 0.823 -0.0635 -0.75 0.8781 -0.0327 -0.49 -0.8747 -0.9795 3119180 ChemDiv3_007336 COc1ccc(NC(=C2C(=O)CC(C)(C)CC2=O)CCCN3C(=O)c4ccccc4C3=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N11 compound treatment 0.8581 -0.0285 -0.33 0.8712 -0.0395 -0.59 -0.6563 -0.9628 3027294 ChemDiv3_007337 CCOC(=O)c1ccc2nc(nc(NCCc3ccc(OC)cc3)c2c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N12 compound treatment 0.8343 -0.0522 -0.61 0.8662 -0.0445 -0.67 -0.9067 -0.999 1740813 ChemDiv3_007338 COc1ccc(cc1)n2c(=O)c3ccc(cc3[nH]c2=S)C(=O)N4CCN(CC4)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N13 compound treatment 0.8388 -0.0478 -0.56 0.87 -0.0407 -0.61 -0.8292 -0.999 3027297 ChemDiv3_007339 COc1ccc(Cn2c(C)cc(O)cc2=O)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N14 compound treatment 0.7766 -0.11 -1.29 0.8627 -0.0481 -0.72 -1.4238 -0.9625 1296230 ChemDiv3_007340 Cc1ccc(NC(=O)c2ccc3c(=O)n(Cc4ccco4)c(=S)[nH]c3c2)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N15 compound treatment 0.8035 -0.0831 -0.97 0.8766 -0.0342 -0.51 -1.0526 -0.9552 3027299 ChemDiv3_007341 OCn1c2CCCCc2c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N16 compound treatment 0.8051 -0.0814 -0.96 0.9177 0.00694 0.1 -0.6018 -0.6261 3119181 ChemDiv3_007342 Cc1ccc(cc1C)N2C3=C(C(C4=C2CC(C)(C)CC4=O)c5cccs5)C(=O)CC(C)(C)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N17 compound treatment 0.785 -0.102 -1.19 0.8657 -0.0451 -0.68 -1.3218 -0.9642 3027303 ChemDiv3_007343 Brc1ccc(cc1)C(=O)C(C(=O)N2CCCCC2)n3ccccc3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N18 compound treatment 0.8575 -0.029 -0.34 0.954 0.0433 0.65 0.2194 0.2986 3119182 ChemDiv3_007344 CCOC(=O)c1cnc2c(OC)cccc2c1NC3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N19 compound treatment 0.8299 -0.0566 -0.66 0.9326 0.0219 0.33 -0.2375 -0.3204 3027305 ChemDiv3_007345 CCOc1ccc(/C=N/n2c(C)nc3ccccc3c2=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N20 compound treatment 0.8417 -0.0448 -0.53 0.8968 -0.0139 -0.21 -0.5199 -0.9184 1741518 ChemDiv3_007346 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCC(C)C4)nc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N21 compound treatment 0.8586 -0.028 -0.33 0.9248 0.014 0.21 -0.0828 -0.2122 3027307 ChemDiv3_007347 COc1cc(/C=N/c2ccc(C)cc2)ccc1OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N22 compound treatment 0.8496 -0.037 -0.43 0.9096 -0.00117 -0.02 -0.3191 -0.7351 1286138 ChemDiv3_007348 COc1ccc(cc1)C(=O)NCCn2cc(SCC(=O)N3CCCCC3)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N23 mock treatment 0.8566 -0.03 -0.35 0.9219 0.0112 0.17 -0.1299 -0.3334 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 N24 mock treatment 0.8927 0.00616 0.07 0.9191 0.00832 0.13 0.1396 0.9661 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O01 compound treatment 0.9128 0.0262 0.31 0.95 0.0393 0.59 0.6356 0.9539 1788832 ChemDiv3_007349 O=C(N(Cc1ccccc1)Cc2ccccc2)c3nc4ncccn4n3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O02 compound treatment 0.895 0.00843 0.1 0.9266 0.0159 0.24 0.2392 0.9235 3119183 ChemDiv3_007350 COc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cccc4cccnc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O03 compound treatment 0.8899 0.00331 0.04 0.9357 0.0249 0.37 0.2926 0.7761 3027446 ChemDiv3_007351 COc1ccc2nc3C(=O)c4ccccc4C(=O)c3nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O04 compound treatment 0.8738 -0.0128 -0.15 0.9321 0.0213 0.32 0.1207 0.3408 3119184 ChemDiv3_007352 OC(=O)c1ccc2[nH]c(CCc3nc4cc(ccc4[nH]3)C(=O)O)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O05 compound treatment 0.8541 -0.0324 -0.38 0.9115 7.57E-4 0.01 -0.2612 -0.6857 3027447 ChemDiv3_007353 CCSC1=C(C#N)C(=O)NCS1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O06 compound treatment 0.8756 -0.011 -0.13 0.9529 0.0422 0.63 0.3577 0.5522 3119185 ChemDiv3_007354 Clc1ccccc1C2N=C(Nc3nc4ccccc4s3)NC5=C2C(=O)CCC5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O07 compound treatment 0.8818 -0.0048 -0.06 0.8951 -0.0156 -0.24 -0.2062 -0.8522 3027478 ChemDiv3_007355 COc1ccc(cc1)C2=Cc3ccccc3C(C)(C)O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O08 compound treatment 0.8414 -0.0452 -0.53 0.9046 -0.0061 -0.09 -0.4399 -0.8173 3119186 ChemDiv3_007356 CC1(C)CC(=O)C2=C(C1)NCN(Cc3ccc4OCOc4c3)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O09 compound treatment 0.86 -0.0265 -0.31 0.8899 -0.0208 -0.31 -0.4417 -1.0 3119187 ChemDiv3_007357 Fc1ccc(cc1)C2Nn3c(nnc3SC2C(=O)Nc4ccccc4C(F)(F)F)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O10 compound treatment 0.8605 -0.0261 -0.31 0.8836 -0.0271 -0.41 -0.5045 -0.99 3027482 ChemDiv3_007358 CCCC[N+]1(C)C2CCC1CC(O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O11 compound treatment 0.8507 -0.0358 -0.42 0.8639 -0.0469 -0.7 -0.7957 -0.9695 3027483 ChemDiv3_007359 OCCNS(=O)(=O)c1cccc2cccnc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O12 compound treatment 0.848 -0.0385 -0.45 0.8604 -0.0504 -0.76 -0.8552 -0.9696 3119188 ChemDiv3_007360 Cc1ccc2oc(c(CN3CCOCC3)c(=O)c2c1)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O13 compound treatment 0.8706 -0.0159 -0.19 0.9138 0.00302 0.05 -0.0999 -0.5198 3027487 ChemDiv3_007361 CCCN1CC2CCCC3(C1)C(=O)NC4(CCCCC4)N=C23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O14 compound treatment 0.8588 -0.0278 -0.33 0.8959 -0.0148 -0.22 -0.3883 -0.983 3119189 ChemDiv3_007362 CC1CN(CC(C)O1)c2nc3ccccc3nc2SCC(=O)Nc4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O15 compound treatment 0.8572 -0.0294 -0.34 0.9169 0.00618 0.09 -0.1782 -0.4989 3119190 ChemDiv3_007363 Sc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O16 compound treatment 0.7548 -0.132 -1.55 0.8699 -0.0408 -0.61 -1.5279 -0.9181 3027489 ChemDiv3_007364 CCn1c(=N)n(CCCOc2ccc(Br)cc2)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O17 compound treatment 0.8406 -0.0459 -0.54 0.9082 -0.00251 -0.04 -0.408 -0.7547 3119191 ChemDiv3_007365 COc1cccc(CN2c3cccc4cccc(c34)S2(=O)=O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O18 compound treatment 0.8525 -0.0341 -0.4 0.8926 -0.0181 -0.27 -0.4758 -0.9825 3027491 ChemDiv3_007366 CN(C)C1=NC(N=C(C)O1)(C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O19 compound treatment 0.8215 -0.0651 -0.76 0.9056 -0.00511 -0.08 -0.5945 -0.7743 3119192 ChemDiv3_007367 CN(CCO)C(=O)c1ccc-2c(c1)C(=O)c3ccccc32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O20 compound treatment 0.8592 -0.0274 -0.32 0.9015 -0.00922 -0.14 -0.3254 -0.9294 3027493 ChemDiv3_007368 FC(F)(F)C1(C2CC(C=C2)N1C(=O)c3ccncc3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O21 compound treatment 0.841 -0.0455 -0.53 0.8793 -0.0314 -0.47 -0.7118 -0.9981 3119193 ChemDiv3_007369 Cc1oc2C(=O)c3ccccc3C(=O)c2c1C(=O)N4CCc5ccccc5C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O22 compound treatment 0.9706 0.0841 0.99 0.999 0.0882 1.33 1.6361 0.9893 1582951 ChemDiv3_007370 CCN1CCN(CC1)C(c2cccnc2)c3ccc4cccnc4c3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O23 mock treatment 0.8488 -0.0378 -0.44 0.9026 -0.00809 -0.12 -0.3994 -0.8692 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 O24 mock treatment 0.9092 0.0227 0.27 0.9258 0.0151 0.23 0.3489 0.9968 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P01 compound treatment 1.0681 0.182 2.13 0.9708 0.06 0.9 2.1449 0.9269 1619302 ChemDiv3_007371 Cc1[nH]c2ccccc2c1C(Nc3cc(C)ccn3)c4ccc(Cl)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P02 compound treatment 1.0143 0.128 1.5 0.9745 0.0638 0.96 1.7383 0.9767 3119194 ChemDiv3_007372 Cc1ccc2NC(C3CC=CC3c2c1)c4ccc(/N=C/c5ccccc5)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P03 compound treatment 0.9123 0.0257 0.3 0.9149 0.00412 0.06 0.2574 0.8349 3027529 ChemDiv3_007373 CC(=O)N1CN(CCCn2ccnc2)Cc3c4CCCCc4sc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P04 compound treatment 0.9021 0.0156 0.18 0.9207 0.01 0.15 0.2358 0.9953 3027531 ChemDiv3_007374 O=S(=O)(Nc1ccccc1)/C=C/c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P05 compound treatment 0.9225 0.036 0.42 0.9347 0.024 0.36 0.5537 0.9969 3119195 ChemDiv3_007375 Fc1ccc(cc1)N2CCN(CC2)C(=O)CN3CC(=O)Oc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P06 compound treatment 0.9168 0.0302 0.35 1.0119 0.101 1.52 1.3264 0.8493 1922912 ChemDiv3_007376 OC(CC(=O)/C=C/c1ccccc1)(c2ccccc2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P07 compound treatment 0.9242 0.0377 0.44 0.8965 -0.0142 -0.21 0.1616 0.3293 3027533 ChemDiv3_007377 COC(=O)c1oc2CC(C)(C)c3nc4ccccc4nc3-c2c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P08 compound treatment 0.9044 0.0179 0.21 0.9137 0.00298 0.04 0.18 0.8394 1600357 ChemDiv3_007378 CCc1ccc(cc1)N2NC(=O)C(=C(C)C)C2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P09 compound treatment 0.8795 -0.00704 -0.08 0.9225 0.0118 0.18 0.0671 0.3428 3119196 ChemDiv3_007379 Cc1ccc(Sc2sc(=O)n(C)c2S(=O)(=O)c3ccc(C)cc3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P10 compound treatment 0.891 0.00446 0.05 0.9208 0.0101 0.15 0.144 0.8994 1389317 ChemDiv3_007380 S=C(NCCc1ccccc1)N2CCc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P11 compound treatment 0.8849 -0.00169 -0.02 0.9041 -0.00659 -0.1 -0.0841 -0.8322 3119197 ChemDiv3_007381 Cc1cc2OC(=C(C#N)C(c3ccccc3)c2c(=O)n1Cc4ccccn4)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P12 compound treatment 0.884 -0.0026 -0.03 0.9181 0.00742 0.11 0.0573 0.4954 1520017 ChemDiv3_007382 O=C(NCC1CCCO1)c2ccc3c(=O)n(c4ccccc4)c(=S)[nH]c3c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P13 compound treatment 0.8689 -0.0176 -0.21 0.9257 0.015 0.23 0.0129 0.0422 3027536 ChemDiv3_007383 COc1ccc(CCn2c(C)cc(O)cc2=O)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P14 compound treatment 0.8782 -0.0084 -0.1 0.9205 0.00978 0.15 0.0342 0.1934 1672880 ChemDiv3_007384 COc1ccc(CCNC(=O)c2ccc3c(=O)n(CC4CCCO4)c(=S)[nH]c3c2)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P15 compound treatment 0.8704 -0.0161 -0.19 0.9352 0.0245 0.37 0.1264 0.3055 3027538 ChemDiv3_007385 O=C1CCC(=O)N1CCOP2(=O)COc3ccccc3OC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P16 compound treatment 0.8445 -0.042 -0.49 0.9066 -0.00417 -0.06 -0.3929 -0.7906 3119321 ChemDiv3_007386 CCN(CC)CCN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4cccc(F)c4)C(=O)CC(C)(C)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P17 compound treatment 0.9741 0.0875 1.03 1.0349 0.124 1.87 2.0471 0.9603 3027592 ChemDiv3_007387 Oc1ccccc1CNCc2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P18 compound treatment 0.8565 -0.0301 -0.35 0.9135 0.00281 0.04 -0.2197 -0.6179 3119322 ChemDiv3_007388 CCOC(=O)c1cnc2c(OC)cccc2c1N3CCC4(CC3)OCCO4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P19 compound treatment 0.856 -0.0306 -0.36 0.9234 0.0127 0.19 -0.1189 -0.2923 1582507 ChemDiv3_007389 CC(C)c1ccc(CNC(=O)CCc2ccccc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P20 compound treatment 0.8514 -0.0352 -0.41 0.8851 -0.0256 -0.38 -0.5641 -0.9994 3119323 ChemDiv3_007390 COC(=O)c1ccc2n(C)/c(=N\C(=O)c3ccc(cc3)S(=O)(=O)N4CCCCC4C)/sc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P21 compound treatment 0.865 -0.0215 -0.25 0.9114 6.42E-4 0.01 -0.1719 -0.6796 1257313 ChemDiv3_007391 O=C1N(CCSC(=S)N2CCSCC2)Cc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P22 compound treatment 0.8674 -0.0192 -0.22 0.8999 -0.0108 -0.16 -0.274 -0.9874 1190401 ChemDiv3_007392 Cc1cccc(NC(=O)CSc2cn(CCNC(=O)c3ccc(F)cc3)c4ccccc24)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P23 mock treatment 0.9151 0.0285 0.33 0.9183 0.0076 0.11 0.3177 0.8976 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2021 P24 mock treatment 0.9419 0.0553 0.65 0.9386 0.0278 0.42 0.7552 0.9774 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A01 compound treatment 0.8933 0.00393 0.05 0.8688 0.0276 0.42 0.3262 0.7808 3063199 Maybridge4_000353 O=C1CCc2cc(ccc2N1)C3=CSC4=NCCN34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A02 compound treatment 0.8762 -0.0131 -0.15 0.8458 0.00462 0.07 -0.0599 -0.354 3178435 Maybridge4_000354 CC1(C)OC(=O)C(C2C3CC4CC(C3)CC2C4)C(=O)O1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A03 compound treatment 0.8926 0.00331 0.04 0.8161 -0.0251 -0.38 -0.24 -0.6311 3178436 Maybridge4_000355 Cc1nc(cs1)c2cc(C#N)c(SCCNC(=O)c3ccc(Cl)cc3Cl)nc2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A04 compound treatment 0.9186 0.0292 0.34 0.8469 0.00565 0.08 0.3028 0.8563 1602887 Maybridge4_000356 CC1(C)Oc2c(C=C1)c3c(=O)cc(oc3c4ccoc24)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A05 compound treatment 0.893 0.0037 0.04 0.7861 -0.0551 -0.83 -0.5552 -0.6691 3063200 Maybridge4_000357 COc1cc(OC)nc(/N=C/N(C)C)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A06 compound treatment 0.8671 -0.0223 -0.26 0.7915 -0.0497 -0.75 -0.7133 -0.901 3178437 Maybridge4_000358 CC1(C)CN=C(NC2CCCCC2)S1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A07 compound treatment 0.8558 -0.0336 -0.39 0.7872 -0.054 -0.81 -0.8523 -0.9449 3178438 Maybridge4_000359 COc1ccc(CCC(=O)CCc2ccc(OC)cc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A08 compound treatment 0.8683 -0.021 -0.25 0.7796 -0.0616 -0.93 -0.8294 -0.8651 3063201 Maybridge4_000360 COc1ccccc1OC(=O)NC(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A09 compound treatment 0.8256 -0.0638 -0.75 0.7577 -0.0835 -1.26 -1.4173 -0.9694 3178439 Maybridge4_000361 CCOC(=O)c1ccc(cc1)C(=S)N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A10 compound treatment 0.7952 -0.0941 -1.1 0.761 -0.0802 -1.21 -1.6341 -0.999 1174208 Maybridge4_000362 CCC1(CCCCN(C)C1=O)c2cccc(OC(=O)C3CCCCC3)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A11 compound treatment 0.7738 -0.115 -1.36 0.7428 -0.0984 -1.48 -2.0045 -0.999 3063202 Maybridge4_000363 CN(C)Cc1c(C)cc(C)cc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A12 compound treatment 0.8154 -0.0739 -0.87 0.7482 -0.093 -1.4 -1.6028 -0.9736 1469863 Maybridge4_000364 O=C(Nc1nc(cs1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A13 compound treatment 0.8203 -0.069 -0.81 0.7605 -0.0807 -1.21 -1.4303 -0.9807 1002608 Maybridge4_000365 CCOC(=O)c1cnc(S)nc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A14 compound treatment 0.8266 -0.0628 -0.74 0.7509 -0.0903 -1.36 -1.4811 -0.9587 1583969 Maybridge4_000366 Clc1cccc(c1)C(=O)NC2CN3CCC2CC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A15 compound treatment 0.8509 -0.0385 -0.45 0.775 -0.0662 -1.0 -1.0228 -0.9361 3063203 Maybridge4_000367 COc1cc(C#N)c2ccc3ccccc3c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A16 compound treatment 0.8678 -0.0215 -0.25 0.7785 -0.0627 -0.94 -0.8457 -0.8659 3178440 Maybridge4_000368 CCNC(=Nc1ccc(Cl)cc1)NCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A17 compound treatment 0.8545 -0.0348 -0.41 0.7692 -0.072 -1.08 -1.0545 -0.9114 1368926 Maybridge4_000369 CC(=O)OCc1ccccc1Sc2ccccc2C(=O)Nc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A18 compound treatment 0.8749 -0.0144 -0.17 0.7955 -0.0457 -0.69 -0.6053 -0.8556 1219932 Maybridge4_000370 C1C=C(Nc2nnnn12)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A19 compound treatment 0.9103 0.0209 0.25 0.7984 -0.0428 -0.64 -0.2817 -0.4088 1528436 Maybridge4_000371 Cn1c(nc2ccccc12)N3C(=O)c4cccc5cccc(C3=O)c45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A20 compound treatment 0.856 -0.0333 -0.39 0.8344 -0.00676 -0.1 -0.3483 -0.8623 1375750 Maybridge4_000372 CC1(CC2CC3(C)C1)CC(C2)(C3)C(=O)NN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A21 compound treatment 0.8684 -0.021 -0.25 0.8325 -0.00872 -0.13 -0.2669 -0.9565 1405005 Maybridge4_000373 O=c1nc2sc3ccccc3n2c(=O)n1c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A22 compound treatment 0.8543 -0.035 -0.41 0.8348 -0.00636 -0.1 -0.358 -0.849 3063251 Maybridge4_000374 C/S(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A23 mock treatment 0.8632 -0.0262 -0.31 0.861 0.0198 0.3 -0.0063 -0.0147 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 A24 mock treatment 0.8556 -0.0337 -0.4 0.8677 0.0265 0.4 0.0022 0.0039 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B01 compound treatment 0.9237 0.0344 0.4 0.8776 0.0364 0.55 0.6722 0.9889 3063252 Maybridge4_000375 C1CN(C1)C(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B02 compound treatment 0.907 0.0177 0.21 0.8346 -0.00661 -0.1 0.0764 0.3321 3063253 Maybridge4_000376 CC1CCC(C)N1c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B03 compound treatment 0.9217 0.0324 0.38 0.829 -0.0122 -0.18 0.1388 0.3287 3063254 Maybridge4_000377 Cc1ccc(cc1)S(=O)(=O)C[C@H]2O[C@H](C[C@@H]2O)n3cc(I)c(=O)[nH]c3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B04 compound treatment 0.9146 0.0253 0.3 0.8087 -0.0325 -0.49 -0.1358 -0.2373 3063255 Maybridge4_000378 C/C(=N\O)/c1cc(Cl)cc(Cl)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B05 compound treatment 0.8564 -0.0329 -0.39 0.7904 -0.0508 -0.76 -0.813 -0.9502 3063256 Maybridge4_000379 CCN(CC)Cc1c(C)c(C)c(C)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B06 compound treatment 0.8581 -0.0312 -0.37 0.8271 -0.0141 -0.21 -0.409 -0.9663 3178441 Maybridge4_000380 Oc1c(Cl)cc(Cl)cc1C2Nc3cc(ccc3-n4cccc24)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B07 compound treatment 0.8427 -0.0467 -0.55 0.7883 -0.0529 -0.8 -0.9495 -0.9835 1227211 Maybridge4_000381 CCC(C)(C)NC(=S)Nc1cccc(OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B08 compound treatment 0.8583 -0.031 -0.36 0.801 -0.0402 -0.6 -0.6853 -0.9706 3178442 Maybridge4_000382 Cc1c(C)c(C)c2[nH]c(SCc3nc(no3)c4ccc(Cl)cc4)nc2c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B09 compound treatment 0.8835 -0.00589 -0.07 0.7916 -0.0496 -0.75 -0.5764 -0.7693 3063257 Maybridge4_000383 CSC1=C(C#N)C(=O)NC(S1)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B10 compound treatment 0.8129 -0.0764 -0.9 0.7828 -0.0584 -0.88 -1.2547 -0.9999 3178443 Maybridge4_000384 C/C(=N\Cc1ccccc1)/c2c(C)cc(C)cc2O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B11 compound treatment 0.7724 -0.117 -1.37 0.7877 -0.0535 -0.8 -1.5397 -0.9676 1417340 Maybridge4_000385 COc1cc(cc(OC)c1OC)C2Nc3ccccc3S2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B12 compound treatment 0.8848 -0.00456 -0.05 0.8507 0.00945 0.14 0.0626 0.4126 1464378 Maybridge4_000386 N#CC1CN(CCc2ccccc2)CN(CCc3ccccc3)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B13 compound treatment 0.7948 -0.0945 -1.11 0.7986 -0.0426 -0.64 -1.2381 -0.9661 1213608 Maybridge4_000387 COc1cc(CO)c(CC(=O)NN)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B14 compound treatment 0.8395 -0.0498 -0.58 0.7789 -0.0623 -0.94 -1.0763 -0.9743 1103050 Maybridge4_000388 CC1(C)OC(=O)C(=Cc2ccc[nH]2)C(=O)O1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B15 compound treatment 0.8619 -0.0274 -0.32 0.848 0.00678 0.1 -0.1554 -0.4604 1559616 Maybridge4_000389 COc1cc(OC)cc(c1)c2nc(N)c3c(C)c(sc3n2)c4ccc(OC)c(OC)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B16 compound treatment 0.8673 -0.022 -0.26 0.7543 -0.0869 -1.31 -1.1066 -0.831 1513039 Maybridge4_000390 Cc1onc(c1NC(=O)N2CCCC2=O)c3c(Cl)cccc3Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B17 compound treatment 0.8768 -0.0125 -0.15 0.7807 -0.0605 -0.91 -0.7472 -0.8106 1918178 Maybridge4_000391 Cc1ccc(NC(=O)C2C(C3CC2C=C3)C(=O)O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B18 compound treatment 0.9004 0.0111 0.13 0.7976 -0.0436 -0.66 -0.3711 -0.5555 3178444 Maybridge4_000392 CS/C(=N\c1ccccc1C(F)(F)F)/N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B19 compound treatment 0.8614 -0.028 -0.33 0.7998 -0.0414 -0.62 -0.6724 -0.9553 3178445 Maybridge4_000393 CCOC(=O)c1nc2ccccc2c(=O)n1/N=C/c3cc(Cl)cc(Cl)c3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B20 compound treatment 0.8762 -0.0131 -0.15 0.821 -0.0202 -0.3 -0.3239 -0.9505 3063259 Maybridge4_000394 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B21 compound treatment 0.877 -0.0123 -0.14 0.8161 -0.0251 -0.38 -0.369 -0.9131 3063260 Maybridge4_000395 CSC(=NS(=O)(=O)c1ccccc1)SC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B22 compound treatment 0.87 -0.0193 -0.23 0.799 -0.0423 -0.64 -0.6094 -0.9034 1232359 Maybridge4_000396 Cc1onc(c1C(=O)ON2C(=O)CCC2=O)c3c(Cl)cccc3Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B23 mock treatment 0.8479 -0.0414 -0.49 0.7941 -0.0471 -0.71 -0.845 -0.983 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 B24 mock treatment 0.869 -0.0204 -0.24 0.8686 0.0273 0.41 0.1219 0.2564 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C01 compound treatment 0.931 0.0417 0.49 0.8531 0.0119 0.18 0.472 0.9067 3063261 Maybridge4_000397 CN(C(=O)COc1cc(n(C)n1)C(F)(F)F)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C02 compound treatment 0.9043 0.015 0.18 0.8657 0.0245 0.37 0.3848 0.943 1015362 Maybridge4_000398 CCOC(=O)c1cccc2C(=O)c3ccccc3-c21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C03 compound treatment 0.8766 -0.0127 -0.15 0.8279 -0.0133 -0.2 -0.2467 -0.9898 1410184 Maybridge4_000399 Cc1ccc(Oc2ncccc2NC(=O)c3ccc(Cl)cc3Cl)c4CCCc41 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C04 compound treatment 0.8901 8.11E-4 0.01 0.8084 -0.0328 -0.49 -0.3423 -0.6933 1430911 Maybridge4_000400 OC(=O)CCC(=O)c1ccc2OCCCOc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C05 compound treatment 0.875 -0.0143 -0.17 0.8142 -0.027 -0.41 -0.4059 -0.9238 3063262 Maybridge4_000401 COc1cc(OC)nc(N/C=N/O)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C06 compound treatment 0.8958 0.00644 0.08 0.8134 -0.0278 -0.42 -0.2422 -0.5701 1594886 Maybridge4_000402 Cn1c(=O)cc(Nc2ccccc2)c3c(=O)n(c4ccccc4)c(=O)n(c5ccccc5)c13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C07 compound treatment 0.8922 0.00291 0.03 0.7849 -0.0563 -0.85 -0.5747 -0.678 3063263 Maybridge4_000403 OC(=O)c1cc(=O)c2c(O)cccc2o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C08 compound treatment 0.8459 -0.0434 -0.51 0.7814 -0.0598 -0.9 -0.9961 -0.9638 3063264 Maybridge4_000404 CC(C)NC(=O)Oc1cccc(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C09 compound treatment 0.8452 -0.0441 -0.52 0.7924 -0.0488 -0.73 -0.8851 -0.9854 3178446 Maybridge4_000405 COC(=O)c1ccc(cc1)C(=O)NN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C10 compound treatment 0.8185 -0.0708 -0.83 0.801 -0.0402 -0.6 -1.0153 -0.9877 1676301 Maybridge4_000406 COC(=O)C1C(NC(C(C(=O)OC)S1(=O)=O)c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C11 compound treatment 0.801 -0.0883 -1.04 0.7948 -0.0465 -0.7 -1.227 -0.9815 3063265 Maybridge4_000407 O=C1CC(=NN1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C12 compound treatment 0.7925 -0.0969 -1.14 0.7908 -0.0504 -0.76 -1.3395 -0.9805 1343081 Maybridge4_000408 CC(C1CC1)N(C(=O)c2cc(C)c(Cl)cc2Cl)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C13 compound treatment 0.8301 -0.0592 -0.69 0.8337 -0.00752 -0.11 -0.5714 -0.8116 1138226 Maybridge4_000409 COc1ccc2c(c1)nnc3n[nH]c(=O)n32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C14 compound treatment 0.8461 -0.0433 -0.51 0.7858 -0.0554 -0.83 -0.948 -0.9719 1419670 Maybridge4_000410 OC(=O)CNC(=O)CSc1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C15 compound treatment 0.8762 -0.0131 -0.15 0.7796 -0.0616 -0.93 -0.7645 -0.8136 3063266 Maybridge4_000411 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C16 compound treatment 0.8888 -5.79E-4 -0.01 0.7903 -0.0509 -0.77 -0.546 -0.7134 3178530 Maybridge4_000412 CCC1(CCCCN(C)C1=O)c2cccc(OC(=O)Nc3ccc(OC(F)(F)F)cc3)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C17 compound treatment 0.8935 0.0042 0.05 0.7645 -0.0767 -1.15 -0.7806 -0.6763 1346230 Maybridge4_000413 N#Cc1cccc2cccc(Sc3ccccc3)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C18 compound treatment 0.8613 -0.0281 -0.33 0.7722 -0.069 -1.04 -0.967 -0.888 1555561 Maybridge4_000414 COc1ccc(OC)c(CCCc2cc(OC)ccc2OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C19 compound treatment 0.8852 -0.00413 -0.05 0.7918 -0.0495 -0.74 -0.5602 -0.7516 3063267 Maybridge4_000415 CCN(CC)C(=O)Nc1ccc(OC)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C20 compound treatment 0.8822 -0.00716 -0.08 0.7752 -0.066 -0.99 -0.7612 -0.7642 1920088 Maybridge4_000416 S=c1nc(c2ccco2)n(Cc3ccccc3)c(=S)n1/C(=N/Cc4ccccc4)/c5ccco5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C21 compound treatment 0.8727 -0.0166 -0.2 0.7994 -0.0418 -0.63 -0.5822 -0.885 3178531 Maybridge4_000417 FC(F)(F)c1cccc(c1)c2nc3ccccn3n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C22 compound treatment 0.8751 -0.0142 -0.17 0.8046 -0.0366 -0.55 -0.5075 -0.8821 3178532 Maybridge4_000418 O=C(/C=C\1/NN=C(NC1=O)c2ccccc2)c3cccs3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C23 mock treatment 0.9011 0.0118 0.14 0.8189 -0.0224 -0.34 -0.1402 -0.3858 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 C24 mock treatment 0.8742 -0.0151 -0.18 0.8334 -0.00777 -0.12 -0.2083 -0.9793 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D01 compound treatment 0.9959 0.107 1.25 0.9685 0.127 1.91 2.2384 0.9787 3178533 Maybridge4_000419 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3NC(=O)[C@H]([C@@H]3c4ccccc4)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D02 compound treatment 0.9159 0.0266 0.31 0.8308 -0.0104 -0.16 0.1098 0.3146 3063268 Maybridge4_000420 FC(F)(F)c1cc(c(Br)c(c1Br)n2cccc2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D03 compound treatment 0.8743 -0.015 -0.18 0.8122 -0.0291 -0.44 -0.4333 -0.92 1316662 Maybridge4_000421 Clc1ccc(NC(=S)NC(Cn2ccnc2)c3ccccc3)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D04 compound treatment 0.8863 -0.00309 -0.04 0.8044 -0.0368 -0.55 -0.4168 -0.7518 1725083 Maybridge4_000422 Cc1c(N)c2c(cc1N3CCCC3)C(C)(C)CC2(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D05 compound treatment 0.8638 -0.0255 -0.3 0.802 -0.0392 -0.59 -0.6293 -0.9506 1718122 Maybridge4_000423 C1c2sc(Nc3ccccc3)nc2-c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D06 compound treatment 0.8577 -0.0316 -0.37 0.812 -0.0292 -0.44 -0.5729 -0.9965 3178534 Maybridge4_000424 FC(F)(F)c1cc(cc(c1)S(=O)(=O)N=C2NCCCN2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D07 compound treatment 0.8623 -0.027 -0.32 0.7812 -0.06 -0.9 -0.8622 -0.9017 1138900 Maybridge4_000425 CC(C)(C)NC(=O)NCc1ccncc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D08 compound treatment 0.8802 -0.00914 -0.11 0.789 -0.0522 -0.79 -0.6311 -0.7963 3178535 Maybridge4_000426 FC(F)(F)c1cc(NCN2C(=O)CCC2=O)cc(c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D09 compound treatment 0.8243 -0.065 -0.76 0.795 -0.0462 -0.7 -1.0311 -0.9989 3178536 Maybridge4_000427 COc1cccc(NC2=C(C#N)C(=O)NC(S2)c3cccc(OC)c3O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D10 compound treatment 0.8091 -0.0803 -0.94 0.7945 -0.0467 -0.7 -1.1623 -0.9895 3063269 Maybridge4_000428 Clc1ccc(cc1)S(=O)(=O)CS(=O)(=O)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D11 compound treatment 0.8374 -0.0519 -0.61 0.8674 0.0262 0.39 -0.1527 -0.2106 1023491 Maybridge4_000429 Oc1ccc(Br)cc1C2Nc3ccccc3S2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D12 compound treatment 0.7783 -0.111 -1.3 0.7541 -0.0871 -1.31 -1.8474 -1.0 3178537 Maybridge4_000430 C/C(=N\O)/c1nnn(c1C)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D13 compound treatment 0.7773 -0.112 -1.32 0.7853 -0.0559 -0.84 -1.525 -0.9767 1381610 Maybridge4_000431 CC1(C)C2CCC(C2)C1(C)NC(=S)NCC3CCCO3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D14 compound treatment 0.817 -0.0723 -0.85 0.7879 -0.0533 -0.8 -1.1673 -0.9996 3178538 Maybridge4_000432 FC(F)(F)c1cccc(CS(=O)(=O)Cc2cccc(c2)C(F)(F)F)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D15 compound treatment 0.8306 -0.0587 -0.69 0.7748 -0.0664 -1.0 -1.1935 -0.9836 1650135 Maybridge4_000433 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)NCc3cccnc3)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D16 compound treatment 0.9045 0.0151 0.18 0.7931 -0.0481 -0.72 -0.3857 -0.518 1002759 Maybridge4_000434 OC(C(O)C(O)c1nc2ccccc2[nH]1)C(O)c3nc4ccccc4[nH]3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D17 compound treatment 0.9258 0.0365 0.43 0.8059 -0.0353 -0.53 -0.0726 -0.1065 1658002 Maybridge4_000435 Cc1c(C)c(C)c(CSC2CC(=O)N(C2=O)c3ccccc3)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D18 compound treatment 0.9524 0.0631 0.74 0.7771 -0.0641 -0.96 -0.1584 -0.1303 3062531 Maybridge4_000436 Clc1ccc(cc1Cl)S(=O)(=O)NC(=N)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D19 compound treatment 0.9052 0.0159 0.19 0.809 -0.0322 -0.48 -0.2106 -0.4061 2117992 Maybridge4_000437 COc1cccc(/C=N/O)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D20 compound treatment 0.9073 0.018 0.21 0.7781 -0.0631 -0.95 -0.5211 -0.5363 1204180 Maybridge4_000438 Clc1ccc(cc1Cl)S(=O)(=O)NCCc2c[nH]c3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D21 compound treatment 0.8913 0.00195 0.02 0.8246 -0.0166 -0.25 -0.1598 -0.6392 3062533 Maybridge4_000439 CS/C(=N\S(=O)(=O)c1ccccc1)/N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D22 compound treatment 0.8926 0.00331 0.04 0.8144 -0.0268 -0.4 -0.2571 -0.636 1417838 Maybridge4_000440 COC(=O)CC1(Oc2ccc(Br)cc2C(=O)N1c3ccc(F)cc3F)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D23 mock treatment 0.8886 -7.51E-4 -0.01 0.8215 -0.0197 -0.3 -0.2157 -0.7278 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 D24 mock treatment 0.8721 -0.0173 -0.2 0.8323 -0.0089 -0.13 -0.2379 -0.9797 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E01 compound treatment 0.9421 0.0527 0.62 0.8419 7.23E-4 0.01 0.4453 0.7194 3062534 Maybridge4_000441 Cn1nc(OC(C)(C)C(=O)Oc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E02 compound treatment 0.9007 0.0114 0.13 0.8249 -0.0163 -0.25 -0.0794 -0.2839 1024184 Maybridge4_000442 CCC(=O)c1ccc(OC)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E03 compound treatment 0.8905 0.00114 0.01 0.8371 -0.00411 -0.06 -0.0343 -0.5418 1519339 Maybridge4_000443 Cc1ccc(Oc2ncccc2NC(=O)CSc3ccccn3)c4CCCc41 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E04 compound treatment 0.8847 -0.00463 -0.05 0.8033 -0.0379 -0.57 -0.4417 -0.771 3062535 Maybridge4_000444 Cc1cc(=O)n(CCO)c(=O)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E05 compound treatment 0.8933 0.00397 0.05 0.7945 -0.0467 -0.7 -0.4638 -0.6588 3178539 Maybridge4_000445 OC(=O)CC(C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C2=CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E06 compound treatment 0.8557 -0.0337 -0.39 0.8091 -0.0321 -0.48 -0.6208 -0.995 1643916 Maybridge4_000446 O=C(N1CCCCC1)c2cccc3Cc4ccccc4-c32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E07 compound treatment 0.8565 -0.0329 -0.39 0.7786 -0.0626 -0.94 -0.9384 -0.9223 3178540 Maybridge4_000447 OC(=O)c1oc(C(=O)O)c(OCc2ccccc2)c1OCc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E08 compound treatment 0.8677 -0.0217 -0.25 0.8253 -0.0159 -0.24 -0.3492 -0.9996 3062536 Maybridge4_000448 O=C(Oc1ccccc1)N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E09 compound treatment 0.8351 -0.0542 -0.64 0.8095 -0.0317 -0.48 -0.7867 -0.9898 1039079 Maybridge4_000449 OC(=O)c1cccc(Cl)c1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E10 compound treatment 0.8129 -0.0765 -0.9 0.8134 -0.0278 -0.42 -0.9298 -0.9395 1423015 Maybridge4_000450 CC(=O)N[C@@H](Cc1ccccc1)C(=O)NN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E11 compound treatment 0.8188 -0.0705 -0.83 0.8231 -0.0181 -0.27 -0.7773 -0.8924 3178542 Maybridge4_000451 OC(Cn1ccccc1=N)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E12 compound treatment 0.8515 -0.0379 -0.44 0.833 -0.00818 -0.12 -0.4012 -0.8702 3062537 Maybridge4_000452 CC(C1CC1)N(C(=O)C)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E13 compound treatment 0.8174 -0.072 -0.84 0.8016 -0.0396 -0.6 -1.0187 -0.9855 1704451 Maybridge4_000453 CN(C)C(=O)c1cccc2C(=O)c3ccccc3-c21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E14 compound treatment 0.872 -0.0173 -0.2 0.8132 -0.028 -0.42 -0.4421 -0.9441 3178543 Maybridge4_000454 CC(C)(C)C(=O)Nc1ccn([C@H]2C[C@H](O)[C@@H](COC(=O)C(C)(C)C)O2)c(=O)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E15 compound treatment 0.8577 -0.0316 -0.37 0.8063 -0.0349 -0.52 -0.6334 -0.9857 3062540 Maybridge4_000455 COc1ccc2c(OC)ccc3C(=O)C=Cc1c32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E16 compound treatment 0.902 0.0126 0.15 0.7995 -0.0417 -0.63 -0.3381 -0.5251 1289531 Maybridge4_000456 Clc1ccc(cc1)C(=O)OC2CN3CCC2CC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E17 compound treatment 0.9367 0.0474 0.56 0.7899 -0.0513 -0.77 -0.1527 -0.1604 1672892 Maybridge4_000457 CNC(=O)c1ccccc1S(=O)c2cccc3cccc(C(=O)O)c23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E18 compound treatment 0.9367 0.0474 0.56 0.7942 -0.047 -0.71 -0.1065 -0.1184 3062541 Maybridge4_000458 COc1ccc(OC)c(CCCCc2cc(OC)ccc2OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E19 compound treatment 1.1268 0.237 2.79 1.0396 0.198 2.98 4.0808 0.9994 3178544 Maybridge4_000459 Clc1ccc(S/C=C/C(=O)c2ccccc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E20 compound treatment 0.913 0.0236 0.28 0.8046 -0.0366 -0.55 -0.1926 -0.3129 3062542 Maybridge4_000460 C/C(=N\O)/C1(CC2(C)CC3(C)CC(C)(C2)C1)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E21 compound treatment 0.9001 0.0108 0.13 0.8298 -0.0114 -0.17 -0.0312 -0.1465 3178545 Maybridge4_000461 CC(=O)OC[C@H]1O[C@@H](Nc2ccc(C)cc2)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E22 compound treatment 0.8724 -0.017 -0.2 0.801 -0.0402 -0.61 -0.5688 -0.8927 3062543 Maybridge4_000462 CC1(C)N(O)C(NC1=S)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E23 mock treatment 0.9297 0.0403 0.47 0.8161 -0.0251 -0.38 0.0681 0.1125 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 E24 mock treatment 0.901 0.0117 0.14 0.8598 0.0186 0.28 0.2952 0.9458 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F01 compound treatment 0.9172 0.0279 0.33 0.811 -0.0302 -0.45 -0.0895 -0.1601 3178546 Maybridge4_000463 Fc1ccc2CC(=O)C(Cc2c1)C3=Cc4ccc(F)cc4CC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F02 compound treatment 0.9191 0.0297 0.35 0.8273 -0.0139 -0.21 0.0984 0.2418 1526672 Maybridge4_000464 COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)n2n4cccc4)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F03 compound treatment 0.8994 0.01 0.12 0.8082 -0.033 -0.5 -0.2671 -0.5243 3062544 Maybridge4_000465 CC(OC(=O)c1cccc(Cl)c1)c2ccc[n+](C)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F04 compound treatment 0.875 -0.0144 -0.17 0.7838 -0.0574 -0.86 -0.7295 -0.8297 1352177 Maybridge4_000466 CSc1cccc(NC(=S)Nc2cc3c(c(N)c2C)C(C)(C)CC3(C)C)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F05 compound treatment 0.8583 -0.031 -0.36 0.7822 -0.059 -0.89 -0.885 -0.9225 3062545 Maybridge4_000467 CC(C=C1C(=O)NC(=O)NC1=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F06 compound treatment 0.8575 -0.0318 -0.37 0.8227 -0.0185 -0.28 -0.4607 -0.9893 3062546 Maybridge4_000468 SC1=NC2(CCCC2)NN1c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F07 compound treatment 0.8586 -0.0308 -0.36 0.786 -0.0552 -0.83 -0.8418 -0.9305 3178547 Maybridge4_000469 C(c1ccc(/N=C/c2ccccn2)cc1)c3ccc(/N=C/c4ccccn4)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F08 compound treatment 0.8369 -0.0524 -0.61 0.787 -0.0542 -0.81 -1.0107 -0.9904 1528873 Maybridge4_000470 O=C1CCC(=O)N1CNc2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F09 compound treatment 0.8559 -0.0334 -0.39 0.816 -0.0252 -0.38 -0.5454 -0.9998 1318293 Maybridge4_000471 CC(C)(C)C(=O)Nc1ccccc1C(=O)NCc2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F10 compound treatment 0.8308 -0.0586 -0.69 0.789 -0.0522 -0.78 -1.0409 -0.9978 3178548 Maybridge4_000472 Clc1ccc(SCc2ccc(NC(=O)Nc3cccc(Cl)c3)o2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F11 compound treatment 0.8642 -0.0251 -0.29 0.8242 -0.017 -0.26 -0.3894 -0.9975 3062547 Maybridge4_000473 NC(=N)Nc1nc(cs1)c2ccc(cc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F12 compound treatment 0.8524 -0.0369 -0.43 0.803 -0.0382 -0.58 -0.7128 -0.9902 3178625 Maybridge4_000474 CS/C(=C(/C#N)\C(=O)c1cccs1)/Nc2cccc(Cl)c2Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F13 compound treatment 0.8844 -0.00494 -0.06 0.85 0.00883 0.13 0.0528 0.3646 3178626 Maybridge4_000475 OC(Cc1ccccc1)(c2ccccc2)c3ccccc3NC(=S)NC4CC5CC4C=C5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F14 compound treatment 0.8702 -0.0191 -0.22 0.8214 -0.0198 -0.3 -0.3698 -0.9902 3062548 Maybridge4_000476 Cc1nnsc1C(=O)Nc2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F15 compound treatment 0.8932 0.00386 0.05 0.7945 -0.0467 -0.7 -0.465 -0.6601 1004988 Maybridge4_000477 ON=C(Cc1ccccc1)Cc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F16 compound treatment 0.8999 0.0106 0.12 0.8051 -0.0361 -0.54 -0.2961 -0.5315 3178627 Maybridge4_000478 Cc1onc(c1C(=O)NC(=S)N2CCOCC2)c3c(Cl)cccc3Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F17 compound treatment 0.9087 0.0194 0.23 0.8114 -0.0298 -0.45 -0.1554 -0.3095 3062549 Maybridge4_000479 NC(=O)Nc1ccc(cc1)/C(=C/c2ccncc2)/C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F18 compound treatment 0.9403 0.0509 0.6 0.7674 -0.0738 -1.11 -0.3622 -0.2873 3062550 Maybridge4_000480 CN(C)C(=S)SCc1c(C)c(C)c(C)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F19 compound treatment 0.903 0.0136 0.16 0.8242 -0.0171 -0.26 -0.0683 -0.2259 3178628 Maybridge4_000481 COc1ccc(cc1)n2c(CC#N)nnc2SCc3c(C)c(C)c(C)c(C)c3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F20 compound treatment 0.9355 0.0462 0.54 0.8397 -0.00146 -0.02 0.3678 0.678 3178629 Maybridge4_000482 CC1(C)ON(C(=N1)NC(=O)NC(=O)c2ccccc2Cl)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F21 compound treatment 0.9027 0.0134 0.16 0.8214 -0.0198 -0.3 -0.0998 -0.2965 3062551 Maybridge4_000483 O=S(=O)(/N=C/1\NCC2CCCC2N1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F22 compound treatment 0.895 0.00562 0.07 0.8114 -0.0298 -0.45 -0.2703 -0.5965 3178630 Maybridge4_000484 CC(CO)(CO)NC(=S)Nc1ccc(F)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F23 mock treatment 0.8978 0.0085 0.1 0.8381 -0.00313 -0.05 0.0373 0.3383 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 F24 mock treatment 0.8785 -0.0108 -0.13 0.8724 0.0312 0.47 0.2424 0.4981 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G01 compound treatment 0.9094 0.02 0.24 0.8429 0.0017 0.03 0.1842 0.7793 1441207 Maybridge4_000485 CC(C)(C)c1cc2[nH]c(=N)[nH]c(=N)n2n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G02 compound treatment 0.8969 0.00754 0.09 0.8365 -0.00471 -0.07 0.0124 0.1095 1390371 Maybridge4_000486 O=c1c(Cc2ccccc2OCc3ccccc3)coc4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G03 compound treatment 0.9098 0.0205 0.24 0.7945 -0.0468 -0.7 -0.3271 -0.4402 3062552 Maybridge4_000487 COc1ccccc1C2OC(=O)C[C@H]2C(=O)NN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G04 compound treatment 0.896 0.00662 0.08 0.7907 -0.0505 -0.76 -0.4822 -0.6315 1630105 Maybridge4_000488 Brc1ccc(cc1)C(=O)c2cc3OCCCOc3cc2Br 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G05 compound treatment 0.8606 -0.0287 -0.34 0.8298 -0.0114 -0.17 -0.3592 -0.9505 1255736 Maybridge4_000489 COc1cc(OC)nc(NCC(NC(=O)c2ccccc2)C(=O)N)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G06 compound treatment 0.8585 -0.0309 -0.36 0.801 -0.0402 -0.6 -0.6838 -0.97 1191076 Maybridge4_000490 CNc1cc(=O)n(c2ccccc2)c(=O)n1c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G07 compound treatment 0.8373 -0.0521 -0.61 0.7922 -0.049 -0.74 -0.953 -0.9957 1024944 Maybridge4_000491 CCOC(=O)c1oc(C(=O)OCC)c(O)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G08 compound treatment 0.8918 0.00245 0.03 0.8905 0.0493 0.74 0.5446 0.734 3062592 Maybridge4_000492 CC(C)(C)c1ccc2cc(C#N)c(C#N)cc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G09 compound treatment 0.8325 -0.0569 -0.67 0.8109 -0.0303 -0.46 -0.7946 -0.9828 3062593 Maybridge4_000493 O=C1N(CCCCN2C(=O)c3ccccc3S2(=O)=O)S(=O)(=O)c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G10 compound treatment 0.8329 -0.0564 -0.66 0.8286 -0.0126 -0.19 -0.6018 -0.8739 3062594 Maybridge4_000494 Cc1ccc(NC(=O)N(C2=NCC(C)(C)S2)c3ccc(F)c(Cl)c3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G11 compound treatment 0.8419 -0.0474 -0.56 0.8272 -0.0141 -0.21 -0.543 -0.9121 1051499 Maybridge4_000495 CC(O)c1ccc2ccccc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G12 compound treatment 0.8513 -0.038 -0.45 0.8267 -0.0145 -0.22 -0.4695 -0.9455 1332464 Maybridge4_000496 OCCOC(=O)c1cccc2C(=O)c3ccccc3-c21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G13 compound treatment 0.861 -0.0284 -0.33 0.8338 -0.00736 -0.11 -0.3137 -0.8939 1397918 Maybridge4_000497 CCCN(CCC)C(=O)c1cccc2C(=O)c3ccccc3-c21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G14 compound treatment 0.8733 -0.0161 -0.19 0.8323 -0.00888 -0.13 -0.2277 -0.9857 3178631 Maybridge4_000498 CC(C)(C)C(=O)OC[C@H]1O[C@H](C[C@@H]1OC(=O)C(C)(C)C)n2cnc3c(N)ncnc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G15 compound treatment 0.8757 -0.0136 -0.16 0.8056 -0.0356 -0.54 -0.4916 -0.8797 3062595 Maybridge4_000499 O=C(OC1=CC(=O)c2cccc3cccc1c23)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G16 compound treatment 0.8964 0.0071 0.08 0.8194 -0.0218 -0.33 -0.1724 -0.5108 1645132 Maybridge4_000500 O=C(NC1CCN(Cc2cccc3ccccc23)CC1)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G17 compound treatment 0.9273 0.038 0.45 0.8183 -0.0229 -0.34 0.0716 0.1271 1430296 Maybridge4_000501 OCc1cccc2cccc(S(=O)c3cccc4cccc(C(=O)O)c34)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G18 compound treatment 0.9321 0.0427 0.5 0.8187 -0.0226 -0.34 0.1148 0.1897 1284168 Maybridge4_000502 Brc1ccc(Cc2csc3ccccc3c2=O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G19 compound treatment 0.9319 0.0425 0.5 0.832 -0.00916 -0.14 0.2556 0.4936 3178632 Maybridge4_000503 FC(F)(F)Oc1ccccc1NC(=O)CC(=O)Nc2ccccc2OC(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G20 compound treatment 0.8918 0.00242 0.03 0.8262 -0.015 -0.23 -0.1399 -0.6134 1186920 Maybridge4_000504 NNC(=O)C1(CCCC2CCC1)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G21 compound treatment 0.8961 0.00681 0.08 0.7945 -0.0467 -0.7 -0.44 -0.6226 3062596 Maybridge4_000505 FC1(C(=O)Nc2c(Cl)c(Cl)ccc2C1=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G22 compound treatment 0.9051 0.0158 0.19 0.8149 -0.0263 -0.4 -0.1484 -0.3399 3178633 Maybridge4_000506 CC(C)(C)OC(=O)Cn1ccc(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G23 mock treatment 0.9056 0.0163 0.19 0.8325 -0.00874 -0.13 0.0422 0.1821 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 G24 mock treatment 0.8965 0.00715 0.08 0.8534 0.0122 0.18 0.1895 0.9367 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H01 compound treatment 0.8806 -0.00877 -0.1 0.8422 0.001 0.02 -0.0622 -0.5975 3178634 Maybridge4_000507 O/N=C(/C1CC2CCC1CC2)\c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H02 compound treatment 0.9077 0.0184 0.22 0.8848 0.0436 0.66 0.6165 0.8925 1138209 Maybridge4_000508 N1C(c2cccn2-c3ccccc13)c4cccnc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H03 compound treatment 0.8701 -0.0193 -0.23 0.8063 -0.0349 -0.52 -0.5306 -0.9293 1326325 Maybridge4_000509 Cc1c(C)c(C)c(CN2C(=O)c3ccccc3C2=O)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H04 compound treatment 0.8986 0.0093 0.11 0.7959 -0.0453 -0.68 -0.4041 -0.5862 3062597 Maybridge4_000510 Cc1c(cc2c(c1n3cccc3)C(C)(C)CC2(C)C)N4CCCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H05 compound treatment 0.8665 -0.0228 -0.27 0.7963 -0.0449 -0.68 -0.6674 -0.918 3178635 Maybridge4_000511 Fc1ccc(cc1)C(=O)CSc2nsc(SCC(=O)c3ccc(F)cc3)c2C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H06 compound treatment 0.8577 -0.0316 -0.37 0.8206 -0.0206 -0.31 -0.4814 -0.996 3178636 Maybridge4_000512 CC(C)C1CCC(C)CC1NC(=S)Nc2cccc(F)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H07 compound treatment 0.8726 -0.0167 -0.2 0.8025 -0.0387 -0.58 -0.5506 -0.8957 1248377 Maybridge4_000513 CC1CCCCN1C(=S)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H08 compound treatment 0.8506 -0.0387 -0.45 0.7957 -0.0455 -0.68 -0.805 -0.9802 3178637 Maybridge4_000514 COc1cccc(OC)c1C(=O)Nc2cc(c(Cl)cc2OC)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H09 compound treatment 0.8499 -0.0395 -0.46 0.8121 -0.0291 -0.44 -0.6368 -0.9996 1054040 Maybridge4_000515 CC(C)C1=NNC(=O)C1(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H10 compound treatment 0.8563 -0.0331 -0.39 0.7994 -0.0418 -0.63 -0.7194 -0.9731 1253333 Maybridge4_000516 Nc1nc2c(nnn2c3ccccc13)C(=O)N4CCOCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H11 compound treatment 0.8622 -0.0271 -0.32 0.8194 -0.0218 -0.33 -0.4568 -0.9999 1700266 Maybridge4_000517 COc1ccc(CCNC(=S)NCCc2ccccc2)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H12 compound treatment 0.8499 -0.0394 -0.46 0.8028 -0.0384 -0.58 -0.7354 -0.994 3178638 Maybridge4_000518 O/N=C(\C#N)/C(=O)c1ccco1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H13 compound treatment 0.8441 -0.0453 -0.53 0.7994 -0.0418 -0.63 -0.8206 -0.9965 1672819 Maybridge4_000519 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H14 compound treatment 0.8441 -0.0452 -0.53 0.8096 -0.0316 -0.48 -0.7117 -0.9985 3178639 Maybridge4_000520 Fc1cc(F)c(NC(=S)N2CCOCC2)c(F)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H15 compound treatment 0.8437 -0.0457 -0.54 0.7869 -0.0543 -0.82 -0.9565 -0.9791 1546700 Maybridge4_000521 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)NN)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H16 compound treatment 0.9064 0.017 0.2 0.82 -0.0212 -0.32 -0.0845 -0.2242 3062598 Maybridge4_000522 Fc1cccc(NCc2cccs2)c1C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H17 compound treatment 0.921 0.0317 0.37 0.8026 -0.0386 -0.58 -0.1475 -0.214 3178640 Maybridge4_000523 NC(=O)Nc1ccc(cc1)/C(=C/c2ccc(Cl)c(Cl)c2)/C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H18 compound treatment 0.9263 0.037 0.43 0.8025 -0.0387 -0.58 -0.1046 -0.144 3062599 Maybridge4_000524 CN(C)C(=S)SCC(=O)c1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H19 compound treatment 0.9314 0.042 0.49 0.8218 -0.0194 -0.29 0.1427 0.249 1221296 Maybridge4_000525 Cc1cc(C)c2-c3[nH]c(nc3C(C)(C)Cc2c1)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H20 compound treatment 0.8854 -0.00398 -0.05 0.8376 -0.00358 -0.05 -0.071 -0.9975 1556252 Maybridge4_000526 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NC(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H21 compound treatment 0.9223 0.033 0.39 0.8052 -0.036 -0.54 -0.1087 -0.1634 3062600 Maybridge4_000527 CC1CN/C(=N/S(=O)(=O)c2ccccc2)/N1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H22 compound treatment 0.8915 0.00215 0.03 0.8141 -0.0271 -0.41 -0.2704 -0.6621 1621149 Maybridge4_000528 CC1CC(C)CN(C1)c2ccc(NS(=O)(=O)c3ccccc3)cc2C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H23 mock treatment 0.9078 0.0184 0.22 0.8362 -0.00498 -0.07 0.1 0.4368 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 H24 mock treatment 0.8852 -0.00413 -0.05 0.8237 -0.0175 -0.26 -0.22 -0.8237 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I01 compound treatment 0.8956 0.00629 0.07 0.8464 0.00517 0.08 0.1072 0.9997 3062601 Maybridge4_000529 Cc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)c3CCCc31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I02 compound treatment 0.8944 0.00501 0.06 0.8388 -0.00243 -0.04 0.0157 0.2274 3178641 Maybridge4_000530 CCOC(=O)CSc1nnc(S)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I03 compound treatment 0.9011 0.0118 0.14 0.846 0.00484 0.07 0.1489 0.9553 3178642 Maybridge4_000531 Cc1nc(cs1)c2cc(C#N)c(SCCNS(=O)(=O)c3ccc(cc3)C(C)(C)C)nc2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I04 compound treatment 0.8612 -0.0282 -0.33 0.8089 -0.0323 -0.49 -0.5771 -0.9824 1202864 Maybridge4_000532 Cc1ccc(cc1)C(=O)C2C(=O)N(C(=O)N(C2=O)c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I05 compound treatment 0.8746 -0.0148 -0.17 0.7981 -0.0431 -0.65 -0.5811 -0.8659 1219965 Maybridge4_000533 Cc1nn(nc1C(=O)ON2C(=O)C3C4OC(C=C4)C3C2=O)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I06 compound treatment 0.9788 0.0895 1.05 0.9295 0.0883 1.33 1.682 0.9933 3062602 Maybridge4_000534 COc1ccc(/C=C\2/C(Oc3ccccc3C2=O)c4ccccc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I07 compound treatment 0.861 -0.0283 -0.33 0.7915 -0.0497 -0.75 -0.7635 -0.9332 1277364 Maybridge4_000535 CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1c2ccc(OC)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I08 compound treatment 0.8438 -0.0455 -0.53 0.8128 -0.0284 -0.43 -0.6796 -0.9938 1178381 Maybridge4_000536 Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)NCC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I09 compound treatment 0.8152 -0.0741 -0.87 0.8246 -0.0166 -0.25 -0.7913 -0.8745 1497959 Maybridge4_000537 CC(C)C1CCC(C)CC1NC(=O)c2cccc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I10 compound treatment 0.8275 -0.0619 -0.73 0.8047 -0.0365 -0.55 -0.9017 -0.9905 1039563 Maybridge4_000538 Clc1ccc2oc(cc(=O)c2c1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I11 compound treatment 0.8753 -0.0141 -0.17 0.8457 0.00452 0.07 -0.0688 -0.385 1035419 Maybridge4_000539 O=C(c1ccccc1)c2ccc(cc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I12 compound treatment 0.86 -0.0293 -0.34 0.8122 -0.029 -0.44 -0.5513 -0.9931 3178724 Maybridge4_000540 Sc1nn(c2ccc(Cl)cc2)c(=S)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I13 compound treatment 0.8684 -0.021 -0.25 0.8131 -0.0281 -0.42 -0.4735 -0.9668 1060199 Maybridge4_000541 CNC(=O)c1cccc2C(=O)c3ccccc3-c21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I14 compound treatment 0.8525 -0.0368 -0.43 0.7957 -0.0455 -0.68 -0.7889 -0.9755 3178725 Maybridge4_000542 NNC(=O)c1cc(n[nH]1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I15 compound treatment 0.8755 -0.0138 -0.16 0.8151 -0.0261 -0.39 -0.3924 -0.9238 1005720 Maybridge4_000543 CN(C)c1ccc(Cc2ccc(cc2)N(C)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I16 compound treatment 0.8802 -0.00916 -0.11 0.8337 -0.00748 -0.11 -0.1556 -0.9997 1587057 Maybridge4_000544 COc1ccccc1C2CCN(Cc3cccc4ccccc34)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I17 compound treatment 0.8677 -0.0216 -0.25 0.8275 -0.0137 -0.21 -0.3255 -0.9948 2075442 Maybridge4_000545 CN1[S+](c2ccccc2C(=O)O)c3cccc4cccc(C1=O)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I18 compound treatment 0.8917 0.0024 0.03 0.7875 -0.0537 -0.81 -0.5509 -0.682 3178726 Maybridge4_000546 Nc1ccccc1SC(CC(=O)c2ccc(Br)cc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I19 compound treatment 0.9126 0.0233 0.27 0.8359 -0.00528 -0.08 0.1371 0.4816 1287387 Maybridge4_000547 OCC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I20 compound treatment 0.915 0.0256 0.3 0.8215 -0.0197 -0.3 0.0031 0.0074 1441014 Maybridge4_000548 OC(=O)C1(CCCC2(CCC1)C(=O)O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I21 compound treatment 0.9015 0.0122 0.14 0.8141 -0.0271 -0.41 -0.1871 -0.4334 1343250 Maybridge4_000549 O=C1C(C2c3ccccc3Oc4ccccc24)C(=O)c5ccccc15 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I22 compound treatment 0.8905 0.00121 0.01 0.8227 -0.0185 -0.28 -0.1868 -0.6701 3062641 Maybridge4_000550 OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I23 mock treatment 0.9209 0.0315 0.37 0.8295 -0.0118 -0.18 0.1369 0.3336 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 I24 mock treatment 0.8706 -0.0188 -0.22 0.8424 0.00122 0.02 -0.1427 -0.6458 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J01 compound treatment 0.8749 -0.0144 -0.17 0.8588 0.0176 0.27 0.0678 0.2154 3062642 Maybridge4_000551 COC(=O)C1CCC(=O)C(C1)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J02 compound treatment 0.9255 0.0362 0.42 0.8911 0.0499 0.75 0.8309 0.9635 1601179 Maybridge4_000552 Oc1ccc2ccccc2c1C3Nc4ccccc4-n5cccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J03 compound treatment 0.8788 -0.0105 -0.12 0.8331 -0.0081 -0.12 -0.1732 -1.0 3062643 Maybridge4_000553 Cc1c(C)c(C)c(CN2CCCCC2)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J04 compound treatment 0.8932 0.00386 0.05 0.8143 -0.0269 -0.4 -0.2537 -0.6239 3062644 Maybridge4_000554 CC(=O)Nc1s/c(=N\c2ccc(C)c(C)c2)/n(C(=O)C)c1c3ccc4OCOc4c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J05 compound treatment 0.8783 -0.0111 -0.13 0.8159 -0.0253 -0.38 -0.361 -0.8976 1342204 Maybridge4_000555 O=S(=O)(N1CCCCC1)c2ccc(NC(=S)Nc3ccc4OCOc4c3)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J06 compound treatment 0.8595 -0.0299 -0.35 0.8147 -0.0265 -0.4 -0.5299 -0.9979 3062645 Maybridge4_000556 Clc1ccc(Cl)c(NC(=S)NC(=N)c2ccccc2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J07 compound treatment 0.8527 -0.0366 -0.43 0.7961 -0.0451 -0.68 -0.7838 -0.9757 3178727 Maybridge4_000557 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(CC3C(=O)Nc4ccccc34)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J08 compound treatment 0.8659 -0.0234 -0.27 0.8013 -0.0399 -0.6 -0.6186 -0.9374 3178728 Maybridge4_000558 CN1CCC2(C(C1)N=NN2c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N4CCOCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J09 compound treatment 0.853 -0.0364 -0.43 0.8432 0.00198 0.03 -0.2808 -0.6561 3062646 Maybridge4_000559 Cc1cc(C)c(C(=O)Nc2cccc(c2)C(F)(F)F)c3CC(C)(C)C(=O)c31 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J10 compound treatment 0.8441 -0.0452 -0.53 0.8165 -0.0247 -0.37 -0.6379 -0.9848 1734956 Maybridge4_000560 Nc1nc2c(nnn2c3ccccc13)c4ccc(Br)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J11 compound treatment 0.8488 -0.0405 -0.48 0.8225 -0.0187 -0.28 -0.5348 -0.9684 3178729 Maybridge4_000561 Cc1c(C)c(C)c(C(O)c2ccccc2)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J12 compound treatment 0.8339 -0.0554 -0.65 0.8245 -0.0167 -0.25 -0.6375 -0.9145 3178730 Maybridge4_000562 COc1ccc(cc1)c2c(C#N)nnn2c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J13 compound treatment 0.8427 -0.0467 -0.55 0.8153 -0.0259 -0.39 -0.6624 -0.986 1646858 Maybridge4_000563 CCN1C(C(CCC1=O)C(=O)O)c2ccc(OC)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J14 compound treatment 0.8376 -0.0517 -0.61 0.7971 -0.0441 -0.66 -0.898 -0.999 1299644 Maybridge4_000564 Fc1cccc(NCCc2ccccn2)c1C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J15 compound treatment 0.8586 -0.0307 -0.36 0.8078 -0.0334 -0.5 -0.6101 -0.9867 3062647 Maybridge4_000565 CCOC(=S)SCc1c(C)c(C)c(C)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J16 compound treatment 0.8574 -0.032 -0.38 0.8169 -0.0243 -0.37 -0.5241 -0.9999 1536926 Maybridge4_000566 O=C(CC#N)NCc1cccs1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J17 compound treatment 0.8446 -0.0447 -0.52 0.8137 -0.0275 -0.41 -0.6635 -0.9931 3178731 Maybridge4_000567 Cc1onc(c1NC(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J18 compound treatment 0.8543 -0.035 -0.41 0.8201 -0.0211 -0.32 -0.5146 -0.9918 1727398 Maybridge4_000568 CCc1cccc(C(C)C)c1NS(=O)(=O)c2ccc(C)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J19 compound treatment 0.8952 0.00589 0.07 0.8331 -0.00809 -0.12 -0.0372 -0.2654 3062649 Maybridge4_000569 Nn1c(nc2ccccc2c1=O)C(=O)NCc3cccnc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J20 compound treatment 0.8864 -0.00297 -0.03 0.8331 -0.00811 -0.12 -0.1109 -0.8744 3178732 Maybridge4_000570 CC1CCCCN1CCCNC(=O)Nc2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J21 compound treatment 0.9153 0.0259 0.3 0.8127 -0.0285 -0.43 -0.0875 -0.1665 3062650 Maybridge4_000571 Clc1ccc(SCc2ccc(C#N)cc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J22 compound treatment 0.8827 -0.00662 -0.08 0.8233 -0.0179 -0.27 -0.2454 -0.8753 3178733 Maybridge4_000572 CC1CN(CC(C)O1)c2ccc(NC(=O)c3ccco3)cc2C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J23 mock treatment 0.9152 0.0258 0.3 0.8332 -0.00797 -0.12 0.1297 0.3976 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 J24 mock treatment 0.9254 0.0361 0.42 0.8603 0.0191 0.29 0.5028 0.9822 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K01 compound treatment 0.8769 -0.0124 -0.15 0.8748 0.0336 0.5 0.2539 0.4834 1258100 Maybridge4_000573 OC(=O)C1CC1C(=O)Nc2ccc(Oc3ccc(Cl)cc3C4CCCCC4)nc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K02 compound treatment 0.8737 -0.0156 -0.18 0.8705 0.0293 0.44 0.1821 0.3811 3062651 Maybridge4_000574 CCOC(=O)CCSc1nnc(S)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K03 compound treatment 0.8606 -0.0287 -0.34 0.8499 0.00868 0.13 -0.1462 -0.4042 1465836 Maybridge4_000575 Fc1ccc(COc2ccc(cc2)C(=O)CSc3ccccn3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K04 compound treatment 0.886 -0.00339 -0.04 0.8207 -0.0205 -0.31 -0.246 -0.7917 1182542 Maybridge4_000576 CC1(CC2(C)CC3(C)C1)CC(C2)(C3)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K05 compound treatment 0.8448 -0.0445 -0.52 0.788 -0.0532 -0.8 -0.9353 -0.9786 3178734 Maybridge4_000577 OC1CCCCCCCCCCC1CCC#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K06 compound treatment 0.8803 -0.00909 -0.11 0.8187 -0.0225 -0.34 -0.3148 -0.8869 3062652 Maybridge4_000578 CC(C)CCNC(=O)Oc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K07 compound treatment 0.8541 -0.0353 -0.41 0.7849 -0.0563 -0.85 -0.8919 -0.9458 3178735 Maybridge4_000579 COc1ccc(OC)c2c(=O)cc(oc12)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K08 compound treatment 0.8511 -0.0382 -0.45 0.823 -0.0182 -0.27 -0.5112 -0.972 1674875 Maybridge4_000580 COc1ccccc1C2CCN(CC2)C(=O)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K09 compound treatment 0.8687 -0.0206 -0.24 0.7992 -0.042 -0.63 -0.6174 -0.9132 3178736 Maybridge4_000581 CC1(C)C2CCC1(C)C(C2)NC(=O)c3cccc(c3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K10 compound treatment 0.8641 -0.0252 -0.3 0.8277 -0.0135 -0.2 -0.3532 -0.9831 1672849 Maybridge4_000582 Cc1onc(c1C(=O)N2CC(C2)Oc3ccc(Cl)cc3)c4c(F)cccc4Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K11 compound treatment 0.941 0.0516 0.61 0.7987 -0.0425 -0.64 -0.023 -0.0262 3062653 Maybridge4_000583 Cc1cc(n[nH]c1=O)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K12 compound treatment 0.8408 -0.0485 -0.57 0.793 -0.0482 -0.73 -0.9156 -0.9929 3062654 Maybridge4_000584 Sc1nc(c2ccccc2)n(n1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K13 compound treatment 0.836 -0.0533 -0.63 0.7995 -0.0417 -0.63 -0.8857 -1.0 1267527 Maybridge4_000585 CC(C)CCNC(=O)c1cccc2C(=O)c3ccccc3-c21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K14 compound treatment 0.857 -0.0324 -0.38 0.8092 -0.0321 -0.48 -0.6094 -0.993 3062655 Maybridge4_000586 O=C1C(CCCC1c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K15 compound treatment 0.8578 -0.0316 -0.37 0.8009 -0.0403 -0.61 -0.6909 -0.972 3178737 Maybridge4_000587 Cc1c(cnc2ccccc12)c3nnnn3c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K16 compound treatment 0.8526 -0.0367 -0.43 0.8247 -0.0165 -0.25 -0.48 -0.9654 1175626 Maybridge4_000588 Cc1ccc(cc1)C(=O)OC2CN3CCC2CC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K17 compound treatment 0.8917 0.00232 0.03 0.8217 -0.0195 -0.29 -0.1881 -0.6387 3178738 Maybridge4_000589 CN1[S+](c2ccccc2C1=O)c3cccc4cccc(C(=O)O)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K18 compound treatment 0.9043 0.015 0.18 0.8113 -0.0299 -0.45 -0.1937 -0.4013 3178739 Maybridge4_000590 CC1(C)C2CCC1(C)c3nn(c(c23)C(F)(F)F)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K19 compound treatment 0.8937 0.00437 0.05 0.8199 -0.0213 -0.32 -0.1898 -0.5862 1361703 Maybridge4_000591 CCOC(Cn1c2ccccc2c3ccccc13)OCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K20 compound treatment 0.8953 0.00599 0.07 0.8253 -0.0159 -0.24 -0.1194 -0.479 1031191 Maybridge4_000592 OC(=O)C1C(C2CCC1C2)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K21 compound treatment 0.9385 0.0491 0.58 0.8499 0.00868 0.13 0.5001 0.8459 1224135 Maybridge4_000593 Cn1c(nc2ccccc12)C(C#N)C(=O)c3ccccc3I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K22 compound treatment 0.8768 -0.0125 -0.15 0.8374 -0.00385 -0.06 -0.1449 -0.917 1062658 Maybridge4_000594 CCOC(=O)C1C(C2c3ccccc3C1c4ccccc24)C(=O)OCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K23 mock treatment 0.9077 0.0184 0.22 0.8451 0.00391 0.06 0.1942 0.868 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 K24 mock treatment 0.8759 -0.0134 -0.16 0.8482 0.00702 0.11 -0.0366 -0.1933 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L01 compound treatment 0.8784 -0.0109 -0.13 0.8787 0.0375 0.56 0.3076 0.5324 3062656 Maybridge4_000595 CCCCN(C(C)C)S(=O)(=O)c1ccc(C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L02 compound treatment 0.8937 0.00441 0.05 0.8692 0.028 0.42 0.3343 0.7881 3178740 Maybridge4_000596 FC(F)(F)c1cccc(c1)/C(=C/C=C/c2ccccc2)/C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L03 compound treatment 0.8628 -0.0265 -0.31 0.8341 -0.00715 -0.11 -0.2959 -0.8993 3062657 Maybridge4_000597 O=C1NC(=O)C(=CC2CCC=CC2)C(=O)N1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L04 compound treatment 0.8952 0.00585 0.07 0.8395 -0.00168 -0.03 0.0307 0.4195 1174872 Maybridge4_000598 Fc1cccc(F)c1C(=O)Nc2cccc(NC(=O)c3c(F)cccc3F)n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L05 compound treatment 0.8863 -0.00306 -0.04 0.81 -0.0312 -0.47 -0.3569 -0.7591 3178741 Maybridge4_000599 COc1ccc(CC/N=C/c2ccc3OCOc3c2)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L06 compound treatment 0.8876 -0.00169 -0.02 0.803 -0.0382 -0.57 -0.42 -0.7311 3062658 Maybridge4_000600 FC(F)(F)c1cc(C#CCN2CCCCC2)cc(c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L07 compound treatment 0.8744 -0.0149 -0.18 0.811 -0.0302 -0.45 -0.4448 -0.9144 3178820 Maybridge4_000601 CC(C)NC(=S)N1CCCN2C1c3ccccc3C2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L08 compound treatment 0.8731 -0.0162 -0.19 0.8174 -0.0238 -0.36 -0.388 -0.9565 3062659 Maybridge4_000602 FC(F)(F)c1cccc(c1C(=O)OCC(=O)c2ccc(Cl)cc2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L09 compound treatment 0.8409 -0.0485 -0.57 0.8441 0.00294 0.04 -0.3708 -0.6502 1236762 Maybridge4_000603 S=C(Nc1ccccc1)Nc2ccccc2n3cccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L10 compound treatment 0.8614 -0.0279 -0.33 0.8186 -0.0226 -0.34 -0.4724 -0.9998 3062660 Maybridge4_000604 COc1ccc(OC)c(c1)S(=O)(=O)c2ccc(Br)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L11 compound treatment 0.8471 -0.0423 -0.5 0.8064 -0.0348 -0.52 -0.7211 -0.9996 1138158 Maybridge4_000605 COc1ccc(OCCC(=O)NN)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L12 compound treatment 0.863 -0.0263 -0.31 0.7912 -0.05 -0.75 -0.7501 -0.9228 3062661 Maybridge4_000606 CN(C)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L13 compound treatment 0.856 -0.0334 -0.39 0.808 -0.0332 -0.5 -0.6297 -0.9928 3178821 Maybridge4_000607 OC(Cc1ccccc1)(c2ccccc2)c3ccccc3/N=C/c4ccc5OCOc5c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L14 compound treatment 0.8525 -0.0368 -0.43 0.8171 -0.0241 -0.36 -0.5618 -0.9961 3178822 Maybridge4_000608 Fc1cccc(N(Cc2cccnc2)C(=S)Nc3ccc(Cl)c(Cl)c3)c1C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L15 compound treatment 0.8646 -0.0248 -0.29 0.8322 -0.00902 -0.14 -0.3015 -0.9397 3062708 Maybridge4_000609 Cc1c(C)c(C)c(CSc2ccccn2)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L16 compound treatment 0.852 -0.0374 -0.44 0.8143 -0.0269 -0.4 -0.5958 -0.9992 3062709 Maybridge4_000610 CC(C)NC(=O)NCc1c(F)cccc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L17 compound treatment 0.8427 -0.0466 -0.55 0.8094 -0.0318 -0.48 -0.7253 -0.9978 3062710 Maybridge4_000611 Cc1c(C)c(C)c(C(=O)/C=N/N)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L18 compound treatment 0.8716 -0.0178 -0.21 0.8471 0.0059 0.09 -0.0847 -0.3739 3062711 Maybridge4_000612 CCc1cccc(C(C)C)c1NC(=O)Nc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L19 compound treatment 0.8442 -0.0452 -0.53 0.827 -0.0142 -0.21 -0.5263 -0.9206 3062712 Maybridge4_000613 COc1ccc(NC(=S)NCCCC2C=NN=C2O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L20 compound treatment 0.8993 0.00998 0.12 0.8382 -0.00299 -0.04 0.051 0.4068 3062713 Maybridge4_000614 CC(C)(C)C1=C(C#N)C(C(=C(NC(=O)NC(=O)c2c(F)cccc2Cl)O1)C#N)c3cccs3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L21 compound treatment 0.8784 -0.0109 -0.13 0.8275 -0.0137 -0.21 -0.2362 -0.9738 1309274 Maybridge4_000615 Cc1cc(C)c(C(=O)Nc2ccc(C)c(C)c2)c(CC(C)(C)C(=O)O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L22 compound treatment 0.8675 -0.0218 -0.26 0.8225 -0.0187 -0.28 -0.3803 -0.9988 3178823 Maybridge4_000616 OCC(CO)(CO)NC(=S)Nc1cc(Cl)cc(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L23 mock treatment 0.8635 -0.0258 -0.3 0.8416 4.4E-4 0.01 -0.2096 -0.6915 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 L24 mock treatment 0.8828 -0.00657 -0.08 0.8508 0.00955 0.14 0.0471 0.2887 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M01 compound treatment 0.9031 0.0138 0.16 0.8711 0.0299 0.45 0.432 0.9051 1443995 Maybridge4_000617 CCCc1ccc(Oc2ccc(NC(=O)C3CC3C(=O)O)cn2)c(OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M02 compound treatment 0.8998 0.0104 0.12 0.8288 -0.0124 -0.19 -0.0456 -0.204 2105374 Maybridge4_000618 Oc1ccc(cc1)C(C#N)N2CCN(CC2)C(C#N)c3ccc(O)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M03 compound treatment 0.9176 0.0283 0.33 0.8339 -0.00735 -0.11 0.1564 0.4474 1235908 Maybridge4_000619 Cc1nc(cs1)c2cc(C#N)c(SCCC(=O)OC(C)(C)C)nc2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M04 compound treatment 0.8837 -0.00567 -0.07 0.8304 -0.0108 -0.16 -0.1616 -0.9228 1332220 Maybridge4_000620 COc1ccc(cc1)C(=O)NC2(CC3CC4CC(C3)C2)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M05 compound treatment 0.8863 -0.00309 -0.04 0.8243 -0.0169 -0.25 -0.2058 -0.7996 3178824 Maybridge4_000621 CN1C2CCC1CC(C2)NC(=O)Cc3ccccc3F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M06 compound treatment 0.8885 -7.93E-4 -0.01 0.8194 -0.0218 -0.33 -0.2389 -0.7268 3062715 Maybridge4_000622 CCNC(=O)Oc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M07 compound treatment 0.8737 -0.0156 -0.18 0.8127 -0.0285 -0.43 -0.4328 -0.9278 3062716 Maybridge4_000623 CN(C)/C=C/C(=O)c1c(O)cc(C)oc1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M08 compound treatment 0.8372 -0.0522 -0.61 0.825 -0.0162 -0.24 -0.605 -0.9182 1250275 Maybridge4_000624 COc1ccccc1C2CCN(CC2)C(=O)C3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M09 compound treatment 0.8684 -0.0209 -0.25 0.8341 -0.00709 -0.11 -0.2489 -0.9303 1731106 Maybridge4_000625 COc1ccc(Br)cc1COC(=O)C2c3ccccc3Oc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M10 compound treatment 0.8575 -0.0318 -0.37 0.8287 -0.0125 -0.19 -0.3975 -0.9497 1917572 Maybridge4_000626 CCOc1ccc2[nH]c(SCc3c(F)c(F)c(F)c(F)c3F)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M11 compound treatment 0.8676 -0.0218 -0.26 0.8091 -0.0321 -0.48 -0.5221 -0.9558 1003070 Maybridge4_000627 Cc1ccc(cc1)S(=O)(=O)c2ccc(C)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M12 compound treatment 0.8853 -0.00407 -0.05 0.8229 -0.0183 -0.28 -0.2288 -0.8175 3062717 Maybridge4_000628 CSc1nc2c(=S)[nH]c(=S)[nH]c2s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M13 compound treatment 0.8693 -0.0201 -0.24 0.7876 -0.0536 -0.81 -0.7364 -0.877 3062718 Maybridge4_000629 O/N=C(/C(=N/O)/c1ccccc1)\c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M14 compound treatment 0.8409 -0.0484 -0.57 0.8222 -0.019 -0.29 -0.6034 -0.9492 1781230 Maybridge4_000630 CCOC(=O)CNc1n[nH]c(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M15 compound treatment 0.8487 -0.0406 -0.48 0.8133 -0.0279 -0.42 -0.6333 -0.998 3062719 Maybridge4_000631 Cc1cc(C)nc(S/C=C/C(=O)c2ccc(Cl)cc2)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M16 compound treatment 0.8552 -0.0341 -0.4 0.8503 0.0091 0.14 -0.1864 -0.4405 1718236 Maybridge4_000632 Cn1c(=O)cc(N2CCOCC2)c3c(=O)n(c4ccccc4)c(=O)n(c5ccccc5)c13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M17 compound treatment 0.8435 -0.0458 -0.54 0.817 -0.0242 -0.36 -0.6376 -0.9819 3178825 Maybridge4_000633 CC(=O)NC1=NN(C(N1C(=O)C)c2cccc3ccccc23)C(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M18 compound treatment 0.8565 -0.0329 -0.39 0.8329 -0.00834 -0.13 -0.3614 -0.8911 1286292 Maybridge4_000634 O=C(NC(C(=O)c1ccccc1)n2cnccc2=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M19 compound treatment 0.8563 -0.033 -0.39 0.8551 0.0138 0.21 -0.1267 -0.2881 1171458 Maybridge4_000635 OC(COCc1ccccc1)Cn2c3ccccc3c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M20 compound treatment 0.8618 -0.0276 -0.32 0.824 -0.0172 -0.26 -0.4115 -0.9938 3062720 Maybridge4_000636 C/S(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M21 compound treatment 0.869 -0.0204 -0.24 0.8132 -0.028 -0.42 -0.4668 -0.9642 1311339 Maybridge4_000637 O=C(C(C#N)c1nc2ccccc2[nH]1)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M22 compound treatment 0.8806 -0.0087 -0.1 0.8189 -0.0223 -0.33 -0.309 -0.8827 1645478 Maybridge4_000638 COC(=O)C1C([C@H]2c3ccccc3[C@@H]1c4ccccc24)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M23 mock treatment 0.8935 0.00419 0.05 0.8362 -0.00498 -0.07 -0.0182 -0.2028 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 M24 mock treatment 0.8929 0.00354 0.04 0.8574 0.0162 0.24 0.2013 0.816 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N01 compound treatment 0.9005 0.0111 0.13 0.8915 0.0503 0.76 0.6269 0.8171 1273203 Maybridge4_000639 CN(C)CC1(CC(=O)O)CCCCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N02 compound treatment 0.8796 -0.00969 -0.11 0.8538 0.0126 0.19 0.0536 0.2425 3178826 Maybridge4_000640 NN/C(=N/S(=O)(=O)c1ccccc1)/N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N03 compound treatment 1.0122 0.123 1.44 0.9685 0.127 1.91 2.3731 0.9902 3062722 Maybridge4_000641 O=C1NC(=O)C(=C/C=C/c2ccccc2)C(=O)N1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N04 compound treatment 0.8799 -0.00946 -0.11 0.833 -0.00817 -0.12 -0.1654 -0.9987 1678177 Maybridge4_000642 COc1cccc(OC)c1C(=O)Nc2ccccc2NC(=O)c3c(OC)cccc3OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N05 compound treatment 0.8493 -0.0401 -0.47 0.7934 -0.0478 -0.72 -0.8405 -0.9789 1073885 Maybridge4_000643 CCOc1ccc(CCC(=O)O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N06 compound treatment 0.8979 0.00854 0.1 0.8291 -0.0121 -0.18 -0.0578 -0.278 3178827 Maybridge4_000644 CS/C(=N\S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/N2CCOCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N07 compound treatment 0.8955 0.00615 0.07 0.817 -0.0242 -0.36 -0.2059 -0.5558 3062723 Maybridge4_000645 Oc1noc(O)c1c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N08 compound treatment 0.8679 -0.0215 -0.25 0.8528 0.0116 0.17 -0.0553 -0.1806 3062724 Maybridge4_000646 NC(=S)NC1CC2CC1C=C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N09 compound treatment 0.8651 -0.0243 -0.28 0.8351 -0.00613 -0.09 -0.2665 -0.8905 3178828 Maybridge4_000647 CCNc1cc(N)[n+](CC)c2[nH]nc(N)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N10 compound treatment 0.8682 -0.0211 -0.25 0.8269 -0.0143 -0.22 -0.3278 -0.9975 1512370 Maybridge4_000648 COc1ccc(cc1CN2CCOCC2)c3cc(c4ccccc4)c(nn3)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N11 compound treatment 0.8697 -0.0196 -0.23 0.8324 -0.00883 -0.13 -0.2566 -0.9658 1288584 Maybridge4_000649 S=C(NC1CC2CC1C=C2)N(CCC#N)Cc3cccnc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N12 compound treatment 0.8992 0.00988 0.12 0.8032 -0.038 -0.57 -0.3225 -0.5525 3178829 Maybridge4_000650 CC(=O)NCc1c(F)cccc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N13 compound treatment 0.8735 -0.0159 -0.19 0.8312 -0.01 -0.15 -0.2382 -0.9946 1566685 Maybridge4_000651 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2cccc(SC)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N14 compound treatment 0.8371 -0.0523 -0.61 0.7947 -0.0465 -0.7 -0.928 -0.9979 3062725 Maybridge4_000652 Fc1cccc(Cl)c1CSc2ccccc2C3=NCCCN3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N15 compound treatment 0.8372 -0.0521 -0.61 0.8009 -0.0403 -0.61 -0.8614 -1.0 3178830 Maybridge4_000653 Cc1c(C)c(C)c(CSC2=NCCS2)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N16 compound treatment 0.8405 -0.0489 -0.57 0.8557 0.0145 0.22 -0.2514 -0.4098 3062726 Maybridge4_000654 Clc1cc(C[n+]2ccccc2)c3OCOCc3c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N17 compound treatment 0.8452 -0.0441 -0.52 0.8102 -0.031 -0.47 -0.696 -0.9986 3062727 Maybridge4_000655 Cn1c(S)nnc1CC#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N18 compound treatment 0.8729 -0.0165 -0.19 0.831 -0.0102 -0.15 -0.2447 -0.9932 3178831 Maybridge4_000656 CC1CC(C)CN(C1)S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N19 compound treatment 0.8624 -0.0269 -0.32 0.8421 9.08E-4 0.01 -0.2137 -0.6759 3178832 Maybridge4_000657 N#Cc1cccc(CSc2nnc(SCc3cccc(C#N)c3)s2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N20 compound treatment 0.8423 -0.0471 -0.55 0.8124 -0.0288 -0.43 -0.6968 -0.9927 3062728 Maybridge4_000658 CC1(C)ON(C(=N1)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N21 compound treatment 0.8908 0.00149 0.02 0.8657 0.0245 0.37 0.2732 0.7398 3178833 Maybridge4_000659 CC1N=C(SCC#N)N2C(C)N=C(SCC#N)N12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N22 compound treatment 0.8573 -0.0321 -0.38 0.8413 1.08E-4 0.0 -0.2649 -0.7041 1490971 Maybridge4_000660 Nc1ccccc1C(=O)NCc2c(F)cccc2Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N23 mock treatment 0.8916 0.00223 0.03 0.819 -0.0222 -0.33 -0.2173 -0.6496 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 N24 mock treatment 0.8804 -0.00895 -0.1 0.8623 0.0211 0.32 0.1503 0.4494 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O01 compound treatment 0.9366 0.0472 0.55 0.8793 0.0381 0.57 0.7973 0.9999 3178834 Maybridge4_000661 COc1ccccc1C2OC(=O)C[C@H]2C(=O)Oc3cccc(c3)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O02 compound treatment 0.9187 0.0294 0.34 0.8611 0.0199 0.3 0.4551 0.9974 3178835 Maybridge4_000662 FC(F)(F)c1cc(NC(=S)NCCN2CCNC2=O)cc(c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O03 compound treatment 0.9028 0.0135 0.16 0.8465 0.00533 0.08 0.1687 0.9501 1251917 Maybridge4_000663 Cc1ccc(OC(C)(C)C(=O)Nc2ccc(Oc3ccc(F)cc3F)nc2)c4CCCc41 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O04 compound treatment 0.8757 -0.0137 -0.16 0.839 -0.0022 -0.03 -0.1368 -0.8351 3178836 Maybridge4_000664 Cc1ccccc1NC2=NCC(C)(C)S2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O05 compound treatment 0.8571 -0.0323 -0.38 0.836 -0.00524 -0.08 -0.3235 -0.8364 1342095 Maybridge4_000665 NC(=O)C1c2ccccc2Oc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O06 compound treatment 0.9094 0.0201 0.24 0.836 -0.00525 -0.08 0.1107 0.4456 3178916 Maybridge4_000666 CC(C)(C)NC(=O)Oc1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O07 compound treatment 0.9025 0.0131 0.15 0.8186 -0.0226 -0.34 -0.1319 -0.3531 1101019 Maybridge4_000667 CC(C)(C)c1cc(c2oc(cc(=O)c2c1)C(=O)O)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O08 compound treatment 0.8927 0.00337 0.04 0.8324 -0.00876 -0.13 -0.0652 -0.4741 1485865 Maybridge4_000668 Clc1ccc(OC2CN(C2)C(=O)NCC=C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O09 compound treatment 0.8975 0.00818 0.1 0.8461 0.00491 0.07 0.1201 0.9916 3178917 Maybridge4_000669 O=C(Oc1ccc2ccccc2c1)C3c4ccccc4Oc5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O10 compound treatment 0.884 -0.00531 -0.06 0.8286 -0.0126 -0.19 -0.1783 -0.8924 1074403 Maybridge4_000670 C1CCC(CC1)Nc2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O11 compound treatment 0.8865 -0.00286 -0.03 0.8305 -0.0107 -0.16 -0.1373 -0.837 1171317 Maybridge4_000671 COc1cc(OC)cc(c1)C(C)(C)OC(=O)NN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O12 compound treatment 0.9156 0.0263 0.31 0.7999 -0.0413 -0.62 -0.2214 -0.3193 1302360 Maybridge4_000672 OC(=O)Cc1cncc(Br)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O13 compound treatment 0.8858 -0.00354 -0.04 0.8358 -0.00541 -0.08 -0.0869 -0.9514 3063089 Maybridge4_000673 C/C(=N\O)/c1c(O)c2ccccc2n(C)c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O14 compound treatment 0.8527 -0.0366 -0.43 0.8268 -0.0144 -0.22 -0.4569 -0.9494 1915396 Maybridge4_000674 CC1(C)OC2C(CO)OC(C2O1)n3cnc4c(=O)[nH]cnc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O15 compound treatment 0.8695 -0.0199 -0.23 0.8319 -0.00926 -0.14 -0.2633 -0.9697 1665055 Maybridge4_000675 CC(=O)OCc1ccccc1Sc2ccccc2C(=O)NCc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O16 compound treatment 0.8628 -0.0265 -0.31 0.8352 -0.00605 -0.09 -0.2846 -0.8771 3063091 Maybridge4_000676 CN1C(=O)/C(=C\NCc2ccccc2)/C(=O)c3c1n(C)c(=O)n(C)c3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O17 compound treatment 0.8737 -0.0156 -0.18 0.838 -0.00324 -0.05 -0.1642 -0.8648 3178918 Maybridge4_000677 COC(=O)c1cc(=O)nc2O[C@@H]3C(O)[C@@H](CO)OC3n21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O18 compound treatment 0.8691 -0.0203 -0.24 0.8495 0.00832 0.13 -0.0798 -0.2968 1458724 Maybridge4_000678 OC(=O)CCC1(CC2CC3CC(O)(C2)C1)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O19 compound treatment 0.8749 -0.0144 -0.17 0.841 -1.8E-4 0.0 -0.1215 -0.7183 3178919 Maybridge4_000679 CCn1c2ccc(Cl)cc2c3cc(Cl)ccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O20 compound treatment 0.8618 -0.0275 -0.32 0.8385 -0.00268 -0.04 -0.2567 -0.7893 1547077 Maybridge4_000680 Cc1ccc(cc1)S(=O)(=O)N=S(Cc2ccccc2)Cc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O21 compound treatment 0.8731 -0.0162 -0.19 0.8372 -0.00396 -0.06 -0.1765 -0.8861 3063093 Maybridge4_000681 CC(C)(C)c1ccc(=O)[nH]n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O22 compound treatment 0.8833 -0.00605 -0.07 0.8451 0.00394 0.06 -0.0083 -0.09 3178920 Maybridge4_000682 Brc1ccc(NC(=O)N2NC(=O)[C@H]([C@@H]2c3ccccc3)c4ccccc4)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O23 mock treatment 0.8683 -0.021 -0.25 0.8264 -0.0148 -0.22 -0.3315 -0.9986 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 O24 mock treatment 0.8931 0.00372 0.04 0.8575 0.0163 0.24 0.2038 0.8203 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P01 compound treatment 0.9559 0.0665 0.78 0.8649 0.0237 0.36 0.8041 0.9367 3063094 Maybridge4_000683 COC(=O)/C=C/c1cn(C2OCC(CO)C2O)c(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P02 compound treatment 0.9222 0.0328 0.39 0.8451 0.00395 0.06 0.3145 0.8064 3178921 Maybridge4_000684 NNC(=O)CS(=O)Cc1cccc(c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P03 compound treatment 0.9229 0.0335 0.39 0.873 0.0318 0.48 0.6164 0.9953 3063095 Maybridge4_000685 O=C1NC(=O)C(=Cc2cccc3ccccc23)C(=O)N1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P04 compound treatment 0.9463 0.0569 0.67 0.886 0.0448 0.67 0.9485 1.0 3178922 Maybridge4_000686 O/N=C/c1ccc(o1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P05 compound treatment 0.8533 -0.036 -0.42 0.9074 0.0662 1.0 0.405 0.3745 1352669 Maybridge4_000687 COc1cccc(NC(=S)NC(Cc2ccccc2)c3ccccc3)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P06 compound treatment 0.8844 -0.00495 -0.06 0.8443 0.0031 0.05 -0.008 -0.1078 1145524 Maybridge4_000688 Clc1ccc(Cl)c(NC(=S)Nc2ccc(nc2)N3CCOCC3)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P07 compound treatment 0.9332 0.0438 0.51 0.8414 2.23E-4 0.0 0.3661 0.7117 1152510 Maybridge4_000689 COc1ccc(CSC2=C(C#N)C(=O)NC3(CCCCC3)S2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P08 compound treatment 0.8816 -0.0077 -0.09 0.8385 -0.00267 -0.04 -0.0923 -0.9332 3063149 Maybridge4_000690 Clc1ccccc1NC(=O)CC2SC(=NC2=O)NC3CC4CC3C=C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P09 compound treatment 0.8645 -0.0249 -0.29 0.8305 -0.0107 -0.16 -0.3206 -0.9609 3178923 Maybridge4_000691 CCNc1cc(N)[n+](CC)c2[nH]nc(/N=C/c3cc(Cl)cc(Cl)c3O)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P10 compound treatment 0.8878 -0.00158 -0.02 0.8362 -0.00496 -0.07 -0.0659 -0.8572 3063150 Maybridge4_000692 N/C(=N\O)/CN1CCCCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P11 compound treatment 0.8817 -0.00765 -0.09 0.8328 -0.00845 -0.13 -0.1534 -0.9855 1138088 Maybridge4_000693 S=C(NC1CC2CC1C=C2)N(CCC#N)CC3CCCO3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P12 compound treatment 0.9223 0.0329 0.39 0.8629 0.0217 0.33 0.5041 0.9964 3063152 Maybridge4_000694 Fc1cccc(Cl)c1CSC2=NCCN2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P13 compound treatment 0.8593 -0.0301 -0.35 0.839 -0.00223 -0.03 -0.2733 -0.7709 1637772 Maybridge4_000695 Cc1onc(c1C(=O)N2CCCN3C2c4ccccc4C3=O)c5ccccc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P14 compound treatment 0.8714 -0.018 -0.21 0.8714 0.0302 0.45 0.1722 0.3438 3063153 Maybridge4_000696 Nn1c(nc2ccccc2c1=O)C(=O)N3CCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P15 compound treatment 0.8618 -0.0276 -0.32 0.8797 0.0385 0.58 0.1805 0.2721 1322891 Maybridge4_000697 CCOC(=O)CCc1ccc(OCc2c(C)c(C)c(C)c(C)c2C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P16 compound treatment 0.8503 -0.039 -0.46 0.8428 0.00162 0.02 -0.3068 -0.6685 3063154 Maybridge4_000698 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NCCCN2CCOCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P17 compound treatment 0.8737 -0.0156 -0.18 0.8665 0.0253 0.38 0.1396 0.3304 1180785 Maybridge4_000699 Cc1c(C)c(C)c(C(=O)CCc2cccc(NC(=O)C3CCC3)c2)c(C)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P18 compound treatment 0.8686 -0.0207 -0.24 0.8584 0.0172 0.26 0.0109 0.0307 3063155 Maybridge4_000700 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NC(=N)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P19 compound treatment 0.8611 -0.0282 -0.33 0.8601 0.0189 0.28 -0.033 -0.0756 3178924 Maybridge4_000701 N/C(=N\O)/Cc1nc(cs1)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P20 compound treatment 0.8608 -0.0285 -0.33 0.8272 -0.014 -0.21 -0.3859 -0.9754 3063157 Maybridge4_000702 Cc1nnsc1C(=O)NC(=O)Nc2cc(Cl)cc(Cl)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P21 compound treatment 0.8722 -0.0172 -0.2 0.8558 0.0146 0.22 0.013 0.0434 3178925 Maybridge4_000703 CC1(C)NN(C(=N1)S)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P22 compound treatment 0.8926 0.00323 0.04 0.8498 0.00857 0.13 0.1179 0.8779 3063158 Maybridge4_000704 CSc1nc(nc(SC)c1Cl)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P23 mock treatment 0.9301 0.0408 0.48 0.857 0.0158 0.24 0.5059 0.9475 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2050 P24 mock treatment 0.8731 -0.0162 -0.19 0.8218 -0.0195 -0.29 -0.3414 -0.9783 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A01 compound treatment 0.9268 0.0558 0.66 0.973 0.0629 0.95 1.1328 0.9839 3561417 BPBio1_000001 CS(=O)(=O)Nc1ccc(Cc2noc(n2)c3ccc4[nH]cc(CCN)c4c3)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A02 compound treatment 0.8966 0.0256 0.3 1.0112 0.101 1.52 1.2877 0.8307 3614564 BPBio1_000002 CN(C)CCCc1cc(ccc1O)C(=O)Nc2ccc(cc2)c3ccncc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A03 compound treatment 0.9194 0.0484 0.57 0.9975 0.0874 1.31 1.3311 0.9294 1164875 BPBio1_000003 Nc1nc2[nH]nnc2c(=O)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A04 compound treatment 0.8708 -2.4E-4 0.0 1.0014 0.0914 1.37 0.9696 0.7057 683 BPBio1_000004 Cc1ncc([N+](=O)[O-])n1CCO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A05 compound treatment 0.8458 -0.0252 -0.3 1.0105 0.1 1.51 0.8585 0.5581 923 BPBio1_000005 NC(=O)NC1NC(=O)NC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A06 compound treatment 0.8592 -0.0118 -0.14 0.9927 0.0826 1.24 0.7806 0.6246 1449 BPBio1_000006 CN1[C@@H](CCC1=O)c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A07 compound treatment 0.8259 -0.0451 -0.53 1.0067 0.0967 1.45 0.6533 0.4223 692 BPBio1_000007 CC(=O)Nc1nnc(s1)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A08 compound treatment 0.8251 -0.0459 -0.54 0.9672 0.0571 0.86 0.2262 0.223 1402 BPBio1_000008 CC[N+](C)(C)c1cccc(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A09 compound treatment 0.8213 -0.0497 -0.58 1.001 0.091 1.37 0.5548 0.3732 1714 BPBio1_000009 CN(C)C(=N)NC(=N)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A10 compound treatment 0.8256 -0.0454 -0.53 0.9965 0.0864 1.3 0.5423 0.3859 1029858 BPBio1_000010 NC(=N)NC(=N)N1CCOCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A11 compound treatment 0.8254 -0.0456 -0.54 0.9649 0.0548 0.82 0.2047 0.2083 3221455 BPBio1_000011 COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCc5cc(OC)c(OC)cc5C4Cc6ccc(OC)c(OC)c6)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A12 compound treatment 0.8305 -0.0405 -0.48 0.947 0.0369 0.56 0.0566 0.0775 678 BPBio1_000012 NCC(CC(=O)O)c1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A13 compound treatment 0.8544 -0.0166 -0.19 0.842 -0.068 -1.02 -0.8611 -0.8268 3064163 BPBio1_000013 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A14 compound treatment 0.8154 -0.0556 -0.65 0.9489 0.0388 0.58 -0.0488 -0.0557 839 BPBio1_000014 Nc1nc2n(COCCO)cnc2c(=O)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A15 compound treatment 0.7949 -0.0761 -0.89 0.9603 0.0502 0.76 -0.0969 -0.0828 1000042 BPBio1_000015 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A16 compound treatment 0.8152 -0.0558 -0.66 0.9659 0.0558 0.84 0.1302 0.1222 35 BPBio1_000016 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A17 compound treatment 0.8086 -0.0624 -0.73 0.9621 0.052 0.78 0.0359 0.0335 807 BPBio1_000017 CCCc1ncc(C[n+]2ccccc2C)c(N)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A18 compound treatment 0.8217 -0.0493 -0.58 0.9628 0.0527 0.79 0.1514 0.1541 1090166 BPBio1_000018 CN(C)c1c(C)n(C)n(c2ccccc2)c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A19 compound treatment 0.8212 -0.0498 -0.58 0.9571 0.047 0.71 0.0865 0.0943 931 BPBio1_000019 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A20 compound treatment 0.8282 -0.0428 -0.5 0.9181 0.00798 0.12 -0.2701 -0.5233 3616486 BPBio1_000020 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A21 compound treatment 0.839 -0.0319 -0.37 0.9068 -0.00329 -0.05 -0.3002 -0.7936 1241 BPBio1_000021 NC(=N)NS(=O)(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A22 compound treatment 0.8381 -0.0329 -0.39 0.8651 -0.045 -0.68 -0.7513 -0.9644 1428 BPBio1_000022 CC(C)NCC(O)COc1cccc2[nH]ccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A23 mock treatment 0.8761 0.0051 0.06 0.8654 -0.0447 -0.67 -0.4331 -0.6416 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 A24 mock treatment 0.8496 -0.0214 -0.25 0.8801 -0.03 -0.45 -0.4965 -0.9616 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B01 compound treatment 0.8784 0.00744 0.09 0.989 0.0789 1.19 0.9009 0.7571 3176924 BPBio1_000023 CC(N)Cc1c[nH]c2ccc(OCc3cccs3)cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B02 compound treatment 0.8827 0.0117 0.14 0.9996 0.0895 1.35 1.0486 0.7752 3614583 BPBio1_000024 CN1CC[C@@H]2CN3CCc4cccc([C@@H]2C1)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B03 compound treatment 0.8862 0.0152 0.18 1.0135 0.103 1.56 1.226 0.783 735 BPBio1_000025 NNC(=O)c1ccncc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B04 compound treatment 0.8565 -0.0145 -0.17 0.9811 0.071 1.07 0.6344 0.5867 1425 BPBio1_000026 CC(N)COc1c(C)cccc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B05 compound treatment 0.8667 -0.00431 -0.05 0.9963 0.0862 1.3 0.8807 0.679 1008060 BPBio1_000027 C1CCc2nnnn2CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B06 compound treatment 0.8455 -0.0255 -0.3 0.9987 0.0886 1.33 0.7302 0.5349 3101 BPBio1_000028 Cc1c(oc2c(cccc2c1=O)C(=O)OCCN3CCCCC3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B07 compound treatment 0.8302 -0.0408 -0.48 1.0187 0.109 1.63 0.8159 0.4794 1480 BPBio1_000029 Clc1ccc2oc(=O)[nH]c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B08 compound treatment 0.8034 -0.0676 -0.79 1.0152 0.105 1.58 0.5568 0.3148 769 BPBio1_000030 CCCCOc1ccc(CC(=O)NO)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B09 compound treatment 0.7971 -0.0739 -0.87 1.0018 0.0918 1.38 0.3623 0.2223 1054660 BPBio1_000031 Cc1ncc([N+](=O)[O-])n1CC(O)CCl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B10 compound treatment 0.8057 -0.0653 -0.77 0.9846 0.0745 1.12 0.251 0.1849 1469 BPBio1_000032 CCC1(CCC(=O)NC1=O)c2ccc(N)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B11 compound treatment 0.7986 -0.0724 -0.85 0.9852 0.0752 1.13 0.1982 0.1401 869 BPBio1_000033 CCC1(C)CC(=O)NC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B12 compound treatment 0.8132 -0.0578 -0.68 0.9482 0.0381 0.57 -0.0744 -0.0838 858 BPBio1_000034 OCC(O)CN1CCN(CC1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B13 compound treatment 0.8135 -0.0575 -0.67 0.931 0.021 0.32 -0.2543 -0.3414 997 BPBio1_000035 NCc1ccc(cc1)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B14 compound treatment 0.8075 -0.0635 -0.75 0.953 0.0429 0.65 -0.0709 -0.0719 3173239 BPBio1_000036 CC(N/C(=N/C#N)/Nc1ccncc1)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B15 compound treatment 0.7735 -0.0975 -1.14 0.9513 0.0413 0.62 -0.37 -0.2843 399 BPBio1_000037 Nc1nc2ccc(OC(F)(F)F)cc2s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B16 compound treatment 0.8921 0.0211 0.25 0.9144 0.00428 0.06 0.2203 0.8624 1185085 BPBio1_000038 CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B17 compound treatment 0.7745 -0.0965 -1.13 0.9644 0.0543 0.82 -0.2238 -0.1603 3173466 BPBio1_000039 [O-][N+](=O)c1ccc(/C=N/N2CC(=O)NC2=O)o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B18 compound treatment 0.7698 -0.101 -1.19 0.9595 0.0494 0.74 -0.3143 -0.2244 3616606 BPBio1_000040 Clc1cccc(Cl)c1NC2=NCCN2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B19 compound treatment 0.8197 -0.0513 -0.6 0.9239 0.0138 0.21 -0.279 -0.4383 3616534 BPBio1_000041 N/N=C/1\N=NC=C2C=CC=CC12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B20 compound treatment 0.8173 -0.0537 -0.63 0.9106 5.31E-4 0.01 -0.4401 -0.6981 1101055 BPBio1_000042 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B21 compound treatment 0.8327 -0.0383 -0.45 0.9179 0.00778 0.12 -0.2351 -0.5063 3273 BPBio1_000043 NNCCc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B22 compound treatment 0.8243 -0.0467 -0.55 0.8871 -0.023 -0.35 -0.6318 -0.9751 690 BPBio1_000044 CC(C)NCC(O)COc1ccccc1CC=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B23 mock treatment 0.8049 -0.0661 -0.78 0.8622 -0.0479 -0.72 -1.0581 -0.9993 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 B24 mock treatment 0.837 -0.034 -0.4 0.8984 -0.0117 -0.18 -0.4057 -0.9319 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C01 compound treatment 0.8845 0.0135 0.16 1.0353 0.125 1.88 1.4437 0.7641 3560538 BPBio1_000045 O=C1CC2(CCCC2)CC(=O)N1CCNCC3COc4ccccc4O3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C02 compound treatment 0.9247 0.0537 0.63 1.0311 0.121 1.82 1.7333 0.8996 3559954 BPBio1_000046 CC(C)NCC(O)COc1ccccc1n2cccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C03 compound treatment 0.8879 0.0169 0.2 1.0227 0.113 1.69 1.3378 0.7845 2898 BPBio1_000047 Cc1cc2CCCS(=O)(=O)c2cc1S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C04 compound treatment 0.8717 7.28E-4 0.01 0.982 0.0719 1.08 0.771 0.7127 715 BPBio1_000048 COc1c2ccoc2c(OC)c3oc(C)cc(=O)c13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C05 compound treatment 0.852 -0.019 -0.22 1.0124 0.102 1.54 0.9301 0.5983 3188932 BPBio1_000049 CCCCNc1ccc(cc1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C06 compound treatment 0.8335 -0.0375 -0.44 1.0243 0.114 1.72 0.9034 0.5096 3616489 BPBio1_000050 CN(C)C/C=C(\c1ccc(Br)cc1)/c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C07 compound treatment 0.8253 -0.0457 -0.54 1.0533 0.143 2.15 1.143 0.5151 1131 BPBio1_000051 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C08 compound treatment 0.815 -0.056 -0.66 1.0141 0.104 1.56 0.6408 0.3778 1451360 BPBio1_000052 OC(C1CCNCC1)(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C09 compound treatment 0.8082 -0.0628 -0.74 1.0364 0.126 1.9 0.8217 0.4034 878 BPBio1_000053 CC(=O)NS(=O)(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C10 compound treatment 0.8424 -0.0286 -0.34 1.008 0.0979 1.47 0.8037 0.5322 1865021 BPBio1_000054 Cn1cnc([N+](=O)[O-])c1Sc2ncnc3[nH]cnc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C11 compound treatment 0.824 -0.047 -0.55 0.9995 0.0894 1.34 0.5606 0.3857 1507 BPBio1_000055 CC(N)CCCC(C)(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C12 compound treatment 0.8087 -0.0623 -0.73 0.95 0.0399 0.6 -0.0933 -0.0987 3069004 BPBio1_000056 C[C@@]12CC[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]2CC[C@@]1(O)C#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C13 compound treatment 0.8141 -0.0569 -0.67 0.9297 0.0197 0.3 -0.2628 -0.3601 1175 BPBio1_000057 Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C14 compound treatment 0.8132 -0.0578 -0.68 0.9479 0.0378 0.57 -0.0769 -0.0868 3060090 BPBio1_000058 NC(=N)N/N=C/c1c(Cl)cccc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C15 compound treatment 0.7859 -0.0851 -1.0 0.9962 0.0861 1.29 0.2093 0.128 1079 BPBio1_000059 N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C16 compound treatment 1.019 0.148 1.74 0.9793 0.0693 1.04 1.9651 0.9701 2038 BPBio1_000060 CCN(CC)C(=S)SSC(=S)N(CC)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C17 compound treatment 0.8151 -0.0559 -0.66 0.9943 0.0843 1.27 0.4318 0.3026 2651 BPBio1_000061 OC[C@H]1O[C@H](C[C@@H]1O)n2cc(I)c(=O)[nH]c2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C18 compound treatment 0.7791 -0.0919 -1.08 0.9597 0.0496 0.75 -0.235 -0.1792 2060486 BPBio1_000062 CC(=O)Oc1ccccc1C(=O)Oc2ccccc2C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C19 compound treatment 0.8162 -0.0548 -0.64 0.9445 0.0344 0.52 -0.0883 -0.1069 861 BPBio1_000063 C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C20 compound treatment 0.8098 -0.0612 -0.72 0.9127 0.00266 0.04 -0.4793 -0.6666 1434 BPBio1_000064 CN1CCN2C(C1)c3ccccc3Cc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C21 compound treatment 0.8252 -0.0458 -0.54 0.93 0.0199 0.3 -0.1686 -0.2742 3616456 BPBio1_000065 Nc1cc(nc(=N)n1O)N2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C22 compound treatment 0.8998 0.0288 0.34 0.937 0.0269 0.4 0.5256 0.9961 440 BPBio1_000066 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C23 mock treatment 0.8163 -0.0547 -0.64 0.8895 -0.0206 -0.31 -0.6732 -0.9442 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 C24 mock treatment 0.8751 0.00405 0.05 0.8993 -0.0108 -0.16 -0.0813 -0.4801 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D01 compound treatment 0.8949 0.0239 0.28 1.0253 0.115 1.73 1.4236 0.811 836181 BPBio1_000067 Clc1cccc(c1)N2CCNCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D02 compound treatment 0.8711 1.44E-4 0.0 1.0047 0.0947 1.42 1.0079 0.7079 3614588 BPBio1_000068 COc1ccc2[nH]cc(CCNCc3ccc(Br)cc3)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D03 compound treatment 0.8851 0.0141 0.17 0.9952 0.0852 1.28 1.0225 0.7919 1262 BPBio1_000069 NC[C@H]1CC[C@@H](CC1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D04 compound treatment 0.8854 0.0144 0.17 0.9998 0.0898 1.35 1.0741 0.7895 1282 BPBio1_000070 NS(=O)(=O)c1cc2c(N=CNS2(=O)=O)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D05 compound treatment 0.8662 -0.00482 -0.06 1.0198 0.11 1.65 1.1271 0.6825 718 BPBio1_000071 Cn1c(=O)n(C)c2ncn(CCO)c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D06 compound treatment 0.8526 -0.0184 -0.22 1.0206 0.11 1.66 1.0225 0.6103 3036 BPBio1_000072 OC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D07 compound treatment 0.8666 -0.00445 -0.05 1.0441 0.134 2.02 1.3882 0.6886 3616541 BPBio1_000073 N[C@H]1C[C@@H]1c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D08 compound treatment 0.8166 -0.0544 -0.64 1.0336 0.124 1.86 0.8622 0.439 1000286 BPBio1_000074 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]2CC[C@@]1(O)C#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D09 compound treatment 0.8511 -0.0199 -0.23 1.0547 0.145 2.18 1.3733 0.6276 3256 BPBio1_000075 CCN(CCCc1ccccc1)CCCc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D10 compound treatment 0.8166 -0.0544 -0.64 1.0162 0.106 1.6 0.6774 0.3941 809 BPBio1_000076 CNCCC=C1c2ccccc2CCc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D11 compound treatment 0.8312 -0.0398 -0.47 0.9876 0.0775 1.17 0.4935 0.393 3069075 BPBio1_000077 OC(=O)COC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D12 compound treatment 0.8249 -0.0461 -0.54 0.9515 0.0414 0.62 0.0579 0.0701 112 BPBio1_000078 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D13 compound treatment 0.8356 -0.0354 -0.41 0.9521 0.042 0.63 0.1536 0.2032 780 BPBio1_000079 CC(C)NNC(=O)c1ccncc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D14 compound treatment 0.791 -0.08 -0.94 1.0309 0.121 1.82 0.6206 0.3035 1000009 BPBio1_000080 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D15 compound treatment 0.7909 -0.0801 -0.94 0.9608 0.0507 0.76 -0.1249 -0.1032 1256 BPBio1_000081 Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D16 compound treatment 0.7808 -0.0902 -1.06 1.0477 0.138 2.07 0.715 0.3077 104 BPBio1_000082 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D17 compound treatment 0.7834 -0.0876 -1.03 1.0073 0.0973 1.46 0.3071 0.1718 741 BPBio1_000083 Cc1ccccc1OCC(O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D18 compound treatment 0.7589 -0.112 -1.32 0.9871 0.077 1.16 -0.1115 -0.0636 746 BPBio1_000084 C(N(Cc1ccccc1)c2ccccc2)C3=NCCN3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D19 compound treatment 0.7993 -0.0717 -0.84 0.9461 0.036 0.54 -0.2119 -0.2117 1018627 BPBio1_000085 NC(=N)NC(=N)NCCc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D20 compound treatment 0.7828 -0.0882 -1.04 0.8951 -0.015 -0.23 -0.8917 -0.8415 1485 BPBio1_000086 CCC(=C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D21 compound treatment 0.819 -0.052 -0.61 0.913 0.00291 0.04 -0.4008 -0.6548 1086 BPBio1_000087 CC(C)C(=O)Nc1ccc([N+](=O)[O-])c(c1)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D22 compound treatment 0.8428 -0.0282 -0.33 0.9174 0.00732 0.11 -0.1564 -0.448 1000106 BPBio1_000088 O=C(C1CCCCC1)N2CC3N(CCc4ccccc34)C(=O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D23 mock treatment 0.8132 -0.0578 -0.68 0.8851 -0.0249 -0.37 -0.7445 -0.961 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 D24 mock treatment 0.8673 -0.00374 -0.04 0.8809 -0.0292 -0.44 -0.3416 -0.7738 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E01 compound treatment 0.8737 0.0027 0.03 1.0316 0.121 1.83 1.3142 0.7193 3614557 BPBio1_000089 CN1C2CCC(Cn3ccnc3C)C(=O)C2c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E02 compound treatment 0.8907 0.0197 0.23 1.0213 0.111 1.67 1.3469 0.7974 3614567 BPBio1_000090 COc1ccccc1N2CCN(CCCCN3C(=O)CCC3=O)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E03 compound treatment 0.906 0.035 0.41 1.0713 0.161 2.42 2.005 0.8153 944 BPBio1_000091 Nc1ccc(cc1)S(=O)(=O)Nc2ccnn2c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E04 compound treatment 0.896 0.025 0.29 1.0214 0.111 1.67 1.3913 0.8187 899 BPBio1_000092 CN1CCc2cccc-3c2[C@H]1Cc4ccc(O)c(O)c43 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E05 compound treatment 0.918 0.0471 0.55 1.0565 0.146 2.2 1.9477 0.8579 3060 BPBio1_000093 CC(C)(CO)[C@@H](O)C(=O)NCCCO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E06 compound treatment 0.8843 0.0133 0.16 1.0623 0.152 2.29 1.7291 0.7534 885 BPBio1_000094 Clc1ccc2Oc3ccccc3N=C(N4CCNCC4)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E07 compound treatment 0.8457 -0.0253 -0.3 1.0296 0.119 1.8 1.0607 0.5825 1159 BPBio1_000095 Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E08 compound treatment 0.8845 0.0135 0.16 1.0647 0.155 2.32 1.7558 0.7535 3326 BPBio1_000096 CN1CCC(=C2c3ccccc3C=Cc4ccccc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E09 compound treatment 0.8525 -0.0185 -0.22 1.0388 0.129 1.94 1.2155 0.6239 3188934 BPBio1_000097 C[C@@]12CC[C@H]3[C@@H](CCC4=C3CCC(=O)C4)[C@@H]2CC[C@@]1(O)C#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E10 compound treatment 0.8199 -0.0511 -0.6 1.025 0.115 1.73 0.7982 0.4364 3616496 BPBio1_000098 NC(=Nc1nc(CSCCC(=N)NS(=O)(=O)N)cs1)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E11 compound treatment 0.8063 -0.0647 -0.76 0.9865 0.0764 1.15 0.2758 0.2002 1433 BPBio1_000099 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E12 compound treatment 0.8542 -0.0168 -0.2 1.0134 0.103 1.55 0.9595 0.6127 3189048 BPBio1_000100 C[C@@]12CC[C@H]3[C@@H](CCC4=Cc5oncc5C[C@]34C)[C@@H]2CC[C@@]1(O)C#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E13 compound treatment 0.8395 -0.0315 -0.37 0.9612 0.0512 0.77 0.2827 0.3313 3616459 BPBio1_000101 CN/C(=N/CCSCc1nc[nH]c1C)/NC#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E14 compound treatment 0.8069 -0.0641 -0.75 0.9808 0.0707 1.06 0.22 0.169 3169 BPBio1_000102 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E15 compound treatment 0.8093 -0.0617 -0.72 0.9719 0.0618 0.93 0.1453 0.1233 1432 BPBio1_000103 CN(C)CCOC(C)(c1ccccc1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E16 compound treatment 0.9296 0.0587 0.69 1.1847 0.275 4.13 3.4071 0.8137 3616497 BPBio1_000104 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)OC%101CC[C@H](C)CN%10 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E17 compound treatment 0.7865 -0.0845 -0.99 0.9763 0.0663 1.0 0.0033 0.0024 1000260 BPBio1_000105 CC[C@H](CO)NCCN[C@H](CC)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E18 compound treatment 0.7898 -0.0812 -0.95 0.9713 0.0612 0.92 -0.0231 -0.0175 1386 BPBio1_000106 CN1CC(c2ccccc2)c3cccc(N)c3C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E19 compound treatment 0.8064 -0.0646 -0.76 0.9517 0.0416 0.63 -0.0938 -0.0954 1108 BPBio1_000107 Cc1cc(=O)n(c2ccccc2)n1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E20 compound treatment 0.7741 -0.0969 -1.14 0.9185 0.0084 0.13 -0.7151 -0.6247 907387 BPBio1_000108 C[C@@]1(N[C@@H]2Cc3ccccc31)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E21 compound treatment 0.8587 -0.0123 -0.14 0.9386 0.0285 0.43 0.2009 0.4442 1079457 BPBio1_000109 Cc1c(O)c(=O)n(c2ccccc2)n1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E22 compound treatment 0.8325 -0.0385 -0.45 0.9137 0.00362 0.05 -0.2812 -0.6176 3069006 BPBio1_000110 CC(=O)CC(c1ccc(cc1)[N+](=O)[O-])c2c(O)c3ccccc3oc2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E23 mock treatment 0.8477 -0.0233 -0.27 0.8923 -0.0178 -0.27 -0.3823 -0.9999 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 E24 mock treatment 0.9232 0.0522 0.61 0.9023 -0.00781 -0.12 0.3504 0.5615 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F01 compound treatment 0.9139 0.0429 0.5 1.0601 0.15 2.26 1.951 0.8441 1101182 BPBio1_000111 Clc1cncc(n1)N2CCNCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F02 compound treatment 0.9037 0.0327 0.38 1.0269 0.117 1.76 1.5131 0.8418 885651 BPBio1_000112 NC(=N)NC(=N)Nc1cccc(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F03 compound treatment 0.8733 0.00234 0.03 1.0412 0.131 1.97 1.4143 0.7169 1081 BPBio1_000113 Cc1c(N)c(=O)n(c2ccccc2)n1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F04 compound treatment 0.917 0.046 0.54 1.0436 0.133 2.01 1.8008 0.8664 3616617 BPBio1_000114 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@]1(O)C#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F05 compound treatment 0.888 0.017 0.2 1.0344 0.124 1.87 1.463 0.7783 1000096 BPBio1_000115 C1CN2CC(N=C2S1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F06 compound treatment 0.8979 0.0269 0.32 1.0252 0.115 1.73 1.4476 0.8226 938 BPBio1_000116 Cc1ccc(cc1)/C(=C\CN2CCCC2)/c3ccccn3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F07 compound treatment 0.8993 0.0283 0.33 1.0624 0.152 2.29 1.8542 0.8012 719 BPBio1_000117 CN(CC#C)Cc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F08 compound treatment 0.8857 0.0147 0.17 1.0391 0.129 1.94 1.4937 0.767 3060494 BPBio1_000118 CN(C)CC/C=C/1\c2ccccc2COc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F09 compound treatment 0.8961 0.0251 0.29 1.0492 0.139 2.09 1.6879 0.7988 1062 BPBio1_000119 COc1ccccc1OCC(O)COC(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F10 compound treatment 0.8814 0.0104 0.12 1.0099 0.0998 1.5 1.1474 0.7622 1240 BPBio1_000120 CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F11 compound treatment 0.8812 0.0102 0.12 1.0047 0.0946 1.42 1.0911 0.7641 3189063 BPBio1_000121 C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)/c2csc(N)n2)C(=O)N1S(=O)(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F12 compound treatment 0.8627 -0.00835 -0.1 0.9999 0.0898 1.35 0.8861 0.6541 3173092 BPBio1_000122 CN(C)CCOC(c1ccccc1)c2ccccc2.Cn1c(=O)n(C)c2nc(Cl)[nH]c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F13 compound treatment 0.8661 -0.00491 -0.06 0.989 0.0789 1.19 0.7982 0.672 1337 BPBio1_000123 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F14 compound treatment 0.88 0.00896 0.11 1.0022 0.0921 1.39 1.0541 0.7586 1112 BPBio1_000124 CC(C)N(CCC(C(=O)N)(c1ccccc1)c2ccccn2)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F15 compound treatment 0.8136 -0.0574 -0.67 0.9715 0.0614 0.92 0.1771 0.155 724 BPBio1_000125 CCn1cc(C(=O)O)c(=O)c2ccc(C)nc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F16 compound treatment 0.8143 -0.0567 -0.67 0.9798 0.0697 1.05 0.2706 0.2179 1272 BPBio1_000126 Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F17 compound treatment 0.827 -0.044 -0.52 0.9914 0.0814 1.22 0.4999 0.3764 3061416 BPBio1_000127 C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.O[C@H]([C@@H](O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F18 compound treatment 0.7887 -0.0823 -0.97 0.969 0.0589 0.89 -0.0563 -0.043 2359 BPBio1_000128 CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@@H]32)n1c5ccccc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F19 compound treatment 0.8012 -0.0698 -0.82 0.9412 0.0312 0.47 -0.248 -0.2628 1300191 BPBio1_000129 C(Nc1ncnc2nc[nH]c12)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F20 compound treatment 0.8544 -0.0166 -0.19 0.9282 0.0181 0.27 0.0553 0.1652 1393 BPBio1_000130 CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F21 compound treatment 0.8386 -0.0324 -0.38 0.9135 0.00337 0.05 -0.2332 -0.6076 198 BPBio1_000131 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F22 compound treatment 0.816 -0.055 -0.65 0.916 0.00594 0.09 -0.393 -0.6034 1215 BPBio1_000132 CC(NCCC(c1ccccc1)c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F23 mock treatment 0.8582 -0.0128 -0.15 0.8753 -0.0348 -0.52 -0.4766 -0.8751 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 F24 mock treatment 0.9019 0.0309 0.36 0.9019 -0.00813 -0.12 0.1699 0.4441 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G01 compound treatment 0.8465 -0.0245 -0.29 1.9611 1.05 15.81 10.9738 0.6941 907439 BPBio1_000133 CCCCCCCCCOc1ccc2[nH]cc(CCN)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G02 compound treatment 0.9192 0.0482 0.57 1.0347 0.125 1.87 1.7253 0.8812 3560511 BPBio1_000134 COc1ccc(NC(=O)c2ccc(cc2)c3ccc(cc3C)c4noc(C)n4)cc1OCCN(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G03 compound treatment 0.9048 0.0338 0.4 1.0803 0.17 2.56 2.0913 0.8071 1160 BPBio1_000135 OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G04 compound treatment 0.9147 0.0437 0.51 1.0835 0.173 2.61 2.2061 0.8302 929 BPBio1_000136 Oc1ccc2C[C@H]3N(CC=C)CC[C@]4([C@H]5Oc1c24)[C@@]3(O)CCC5=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G05 compound treatment 0.9249 0.0539 0.63 1.0811 0.171 2.57 2.2662 0.8556 2702 BPBio1_000137 COc1cc(C)nn1c2nc(C)cc(OC)n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G06 compound treatment 0.9311 0.0601 0.71 1.0478 0.138 2.07 1.9636 0.8974 918 BPBio1_000138 CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G07 compound treatment 0.8843 0.0133 0.16 1.0618 0.152 2.28 1.7239 0.7537 697 BPBio1_000139 Cn1c(=O)n(C)c2ncn(CC(O)CO)c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G08 compound treatment 0.891 0.02 0.23 1.0463 0.136 2.05 1.6149 0.783 757 BPBio1_000140 OC(=O)c1cn(C2CC2)c3cc(N4CCNCC4)c(F)cc3c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G09 compound treatment 0.8879 0.0169 0.2 1.0193 0.109 1.64 1.302 0.7867 1061 BPBio1_000141 Nc1nc(N)c2nc(c(N)nc2n1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G10 compound treatment 0.9114 0.0404 0.47 1.0118 0.102 1.53 1.4171 0.8849 1092 BPBio1_000142 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G11 compound treatment 0.909 0.038 0.45 1.0033 0.0932 1.4 1.306 0.8882 1186 BPBio1_000143 Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G12 compound treatment 0.8551 -0.0159 -0.19 1.0322 0.122 1.84 1.1663 0.632 1261 BPBio1_000144 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G13 compound treatment 0.8783 0.00725 0.09 0.9991 0.0891 1.34 1.0072 0.7505 3616468 BPBio1_000145 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3OC(=O)C)N(C)C)[C@@H](C)C[C@@]4(CO4)C(=O)[C@H](C)[C@@H](OC(=O)C)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G14 compound treatment 0.8692 -0.00176 -0.02 1.0057 0.0957 1.44 1.0027 0.6969 3189051 BPBio1_000146 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@]5([C@H]6Oc1c25)[C@@]3(O)CCC6=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G15 compound treatment 0.8729 0.00185 0.02 0.9876 0.0775 1.17 0.8397 0.7202 1259 BPBio1_000147 CCc1nc(N)nc(N)c1c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G16 compound treatment 0.8518 -0.0192 -0.23 1.0075 0.0974 1.47 0.8767 0.5915 1207 BPBio1_000148 CN(C)CCC(c1ccc(Cl)cc1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G17 compound treatment 0.8149 -0.0561 -0.66 0.9793 0.0693 1.04 0.2708 0.2198 1270 BPBio1_000149 C[N+](C)(C)CCCCCC[N+](C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G18 compound treatment 0.8177 -0.0533 -0.63 0.9794 0.0693 1.04 0.2954 0.243 1027 BPBio1_000150 O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CCC6)c54 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G19 compound treatment 0.8058 -0.0652 -0.76 0.9408 0.0307 0.46 -0.2146 -0.2403 1518 BPBio1_000151 OC(=O)c1cc(ccc1O)c2ccc(F)cc2F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G20 compound treatment 0.8109 -0.0601 -0.71 0.9327 0.0226 0.34 -0.2583 -0.3299 2241 BPBio1_000152 COc1ccc(cc1C(=O)NCc2cccnc2)C(=O)NCc3cccnc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G21 compound treatment 0.9121 0.0411 0.48 0.9783 0.0682 1.03 1.0666 0.941 1313 BPBio1_000153 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G22 compound treatment 0.7836 -0.0874 -1.03 0.7945 -0.116 -1.74 -1.9552 -0.9684 1002008 BPBio1_000154 C[C@@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]2C[C@@H](O)[C@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G23 mock treatment 0.8495 -0.0215 -0.25 0.8938 -0.0163 -0.24 -0.3513 -0.9999 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 G24 mock treatment 0.8927 0.0217 0.25 0.8849 -0.0252 -0.38 -0.0874 -0.1917 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H01 compound treatment 0.9696 0.0986 1.16 1.0249 0.115 1.73 2.0394 0.981 3326 BPBio1_000155 CN1CCC(=C2c3ccccc3C=Cc4ccccc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H02 compound treatment 0.9268 0.0558 0.66 1.0603 0.15 2.26 2.0605 0.8761 924 BPBio1_000156 NC(=N)NC(=N)Nc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H03 compound treatment 0.9503 0.0793 0.93 1.0618 0.152 2.28 2.2719 0.9217 1535 BPBio1_000157 COc1ccc(OC)c(c1)C(O)CNC(=O)CN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H04 compound treatment 0.9486 0.0776 0.91 1.0716 0.162 2.43 2.362 0.9104 3069234 BPBio1_000158 CC[C@]1(CCCN2CCc3c4[C@@H]21)C[C@](O)(C(=O)OC)n4c5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H05 compound treatment 0.9364 0.0654 0.77 1.0984 0.188 2.83 2.5451 0.8675 370 BPBio1_000159 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H06 compound treatment 0.9459 0.0749 0.88 1.0829 0.173 2.6 2.4595 0.8964 2797 BPBio1_000160 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H07 compound treatment 0.9424 0.0714 0.84 1.0978 0.188 2.82 2.5885 0.879 1266 BPBio1_000161 CCn1cc(C(=O)O)c(=O)c2cc3OCOc3cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H08 compound treatment 0.9476 0.0766 0.9 1.0381 0.128 1.93 1.9978 0.9399 3176928 BPBio1_000162 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H09 compound treatment 0.9035 0.0325 0.38 1.0421 0.132 1.99 1.6738 0.8278 1298 BPBio1_000163 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H10 compound treatment 0.853 -0.018 -0.21 0.9275 0.0174 0.26 0.0356 0.1057 3189180 BPBio1_000164 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H11 compound treatment 0.9089 0.0379 0.45 1.0489 0.139 2.09 1.7911 0.839 3616559 BPBio1_000165 C[N+]1=Cc2cc3OCOc3cc2CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H12 compound treatment 0.8887 0.0177 0.21 0.9826 0.0725 1.09 0.9179 0.8272 1172 BPBio1_000166 CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H13 compound treatment 0.9093 0.0383 0.45 0.9929 0.0829 1.25 1.1992 0.9052 1331 BPBio1_000167 CC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H14 compound treatment 0.896 0.025 0.29 0.9955 0.0855 1.29 1.1163 0.8467 404 BPBio1_000168 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H15 compound treatment 0.8681 -0.00294 -0.03 0.98 0.0699 1.05 0.719 0.6836 3616563 BPBio1_000169 C[C@H](N)[C@H](O)c1cccc(O)c1.O[C@H]([C@@H](O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H16 compound treatment 0.8626 -0.00835 -0.1 1.0001 0.0901 1.35 0.8884 0.6542 1100 BPBio1_000170 CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H17 compound treatment 0.8484 -0.0226 -0.27 0.9911 0.0811 1.22 0.6744 0.5405 1523 BPBio1_000171 CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H18 compound treatment 0.8416 -0.0294 -0.34 0.9613 0.0512 0.77 0.3011 0.3567 3172 BPBio1_000172 C(/C=C/c1ccccc1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H19 compound treatment 0.8486 -0.0224 -0.26 0.9697 0.0596 0.9 0.4483 0.4798 1436 BPBio1_000173 CCCNC(C)C(=O)Nc1ccccc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H20 compound treatment 0.8435 -0.0275 -0.32 0.8489 -0.0612 -0.92 -0.8782 -0.9012 1001967 BPBio1_000174 C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)C=CC(=O)C=C14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H21 compound treatment 0.9919 0.121 1.42 1.0196 0.11 1.65 2.1684 0.9973 383 BPBio1_000175 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H22 compound treatment 0.811 -0.06 -0.7 0.8825 -0.0275 -0.41 -0.7905 -0.968 1000268 BPBio1_000176 COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H23 mock treatment 0.8384 -0.0326 -0.38 0.9008 -0.0093 -0.14 -0.3694 -0.9069 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 H24 mock treatment 0.8779 0.0069 0.08 0.9136 0.00353 0.05 0.0948 0.9791 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I01 compound treatment 0.9313 0.0603 0.71 1.0747 0.165 2.48 2.2509 0.8743 3561626 BPBio1_000177 COc1ccc2[nH]cc(C3=CCNCC3)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I02 compound treatment 0.9246 0.0536 0.63 1.0356 0.125 1.89 1.7789 0.8944 3614569 BPBio1_000178 CCCCN(CC)CCOc1cccc2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I03 compound treatment 0.94 0.069 0.81 1.0693 0.159 2.39 2.2659 0.8963 779 BPBio1_000179 CCN(CC)CCOC(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I04 compound treatment 0.9697 0.0987 1.16 1.0851 0.175 2.63 2.6805 0.932 3616505 BPBio1_000180 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)C4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I05 compound treatment 0.9708 0.0998 1.17 1.1264 0.216 3.25 3.1279 0.9048 2847 BPBio1_000181 CC(C)c1cc(OC(=O)C)c(C)cc1OCCN(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I06 compound treatment 0.9767 0.106 1.24 1.0818 0.172 2.58 2.7029 0.9436 3069040 BPBio1_000182 CNCC(O)c1ccc(O)c(OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I07 compound treatment 0.9552 0.0842 0.99 1.0734 0.163 2.46 2.4358 0.9199 3068964 BPBio1_000183 NCCc1cc[nH]n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I08 compound treatment 0.9497 0.0787 0.92 1.031 0.121 1.82 1.939 0.9508 2858 BPBio1_000184 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@H]3[C@H](CC(=O)[C@]12C)[C@@]4(C)CCC(=O)C[C@H]4CC3=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I09 compound treatment 0.9406 0.0696 0.82 1.0659 0.156 2.34 2.235 0.9004 1268 BPBio1_000185 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3cc(C)on3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I10 compound treatment 0.9238 0.0528 0.62 1.0544 0.144 2.17 1.9731 0.8742 1610 BPBio1_000186 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I11 compound treatment 0.9093 0.0383 0.45 1.0148 0.105 1.57 1.4313 0.8742 907391 BPBio1_000187 COc1ccc2cc(ccc2c1)C(C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I12 compound treatment 0.8672 -0.00383 -0.04 1.0131 0.103 1.55 1.0637 0.6863 1465 BPBio1_000188 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I13 compound treatment 0.9037 0.0327 0.38 1.0 0.0899 1.35 1.2273 0.8733 1083 BPBio1_000189 C(C1=NCCN1)c2cccc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I14 compound treatment 0.8555 -0.0155 -0.18 0.9819 0.0719 1.08 0.6355 0.5799 1387 BPBio1_000190 OC(C1CCCCN1)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I15 compound treatment 0.9011 0.0301 0.35 1.0219 0.112 1.68 1.4384 0.8373 1821 BPBio1_000191 Clc1ccccc1CN2CCc3sccc3C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I16 compound treatment 0.8801 0.00912 0.11 0.9866 0.0765 1.15 0.8889 0.7696 3487389 BPBio1_000192 Clc1ccc(C(Cn2ccnc2)OCc3c(Cl)cccc3Cl)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I17 compound treatment 0.8686 -0.00236 -0.03 0.9763 0.0662 1.0 0.6848 0.6872 819 BPBio1_000193 CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I18 compound treatment 0.8486 -0.0224 -0.26 0.9846 0.0745 1.12 0.6057 0.5264 3189054 BPBio1_000194 CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@]54CCC(=O)O5)[C@H]13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I19 compound treatment 0.8524 -0.0186 -0.22 0.9719 0.0618 0.93 0.5023 0.5263 3188937 BPBio1_000195 CCC(C)(CN(C)C)OC(=O)c1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I20 compound treatment 0.8495 -0.0215 -0.25 0.9376 0.0275 0.41 0.1141 0.2359 786 BPBio1_000196 CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc4cccnc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I21 compound treatment 0.8515 -0.0195 -0.23 0.9357 0.0256 0.38 0.1101 0.246 362 BPBio1_000197 CCN(CC)CC(=O)Nc1c(C)cccc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I22 compound treatment 0.8021 -0.0689 -0.81 0.8189 -0.0911 -1.37 -1.5409 -0.9683 1000246 BPBio1_000198 C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I23 mock treatment 0.8609 -0.0101 -0.12 0.9329 0.0228 0.34 0.1587 0.4372 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 I24 mock treatment 0.8704 -6.19E-4 -0.01 0.914 0.00389 0.06 0.0363 0.6147 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J01 compound treatment 0.9763 0.105 1.24 1.0494 0.139 2.09 2.3553 0.9683 907239 BPBio1_000199 Clc1ccc2Nc3ccccc3C(=Nc2c1)N4CCNCC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J02 compound treatment 0.9531 0.0821 0.96 1.0745 0.164 2.47 2.4301 0.9156 3614592 BPBio1_000200 Cn1cc(C(=O)C(=O)N[C@H]2CN3CCC2CC3)c4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J03 compound treatment 0.9458 0.0748 0.88 1.0918 0.182 2.73 2.5535 0.8895 3616567 BPBio1_000201 CN/C(=C/[N+](=O)[O-])/NCCSCc1ccc(CN(C)C)o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J04 compound treatment 0.8796 0.00859 0.1 0.9241 0.0141 0.21 0.2208 0.9426 3616626 BPBio1_000202 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3(F)C(=O)C[C@@]21C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J05 compound treatment 0.993 0.122 1.43 1.0734 0.163 2.46 2.7493 0.9669 3069077 BPBio1_000203 OC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J06 compound treatment 1.0016 0.131 1.53 1.0915 0.181 2.73 3.0137 0.9628 1033 BPBio1_000204 CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J07 compound treatment 1.0001 0.129 1.52 1.0686 0.159 2.38 2.7572 0.9761 41 BPBio1_000205 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J08 compound treatment 0.9934 0.122 1.44 1.0889 0.179 2.69 2.9177 0.9569 1019722 BPBio1_000206 CN1CCCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J09 compound treatment 0.9867 0.116 1.36 1.0756 0.166 2.49 2.7202 0.9594 752 BPBio1_000207 CC1CCc2cc(F)cc3c(=O)c(cn1c23)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J10 compound treatment 0.9591 0.0881 1.03 1.0717 0.162 2.43 2.4499 0.9276 1164 BPBio1_000208 CCN(CC)C(=O)N1CCN(C)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J11 compound treatment 0.9408 0.0698 0.82 1.0526 0.143 2.14 2.0946 0.913 1258696 BPBio1_000209 Cc1c(Cl)cccc1Nc2ccccc2C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J12 compound treatment 0.9145 0.0435 0.51 1.0281 0.118 1.77 1.6159 0.8751 1000071 BPBio1_000210 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J13 compound treatment 0.8906 0.0196 0.23 1.0258 0.116 1.74 1.3929 0.7938 1123 BPBio1_000211 Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J14 compound treatment 0.9067 0.0357 0.42 1.0264 0.116 1.75 1.5326 0.8524 1158 BPBio1_000212 C(C(C1CCCCC1)C2CCCCC2)C3CCCCN3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J15 compound treatment 0.9058 0.0348 0.41 0.9915 0.0814 1.22 1.1542 0.8944 3189175 BPBio1_000213 COC1=CC(=O)O[C@H](C1)/C=C/c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J16 compound treatment 0.8773 0.00634 0.07 1.0017 0.0916 1.38 1.0266 0.7442 3480597 BPBio1_000214 CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J17 compound treatment 0.8937 0.0227 0.27 0.9961 0.0861 1.29 1.104 0.8354 1201 BPBio1_000215 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J18 compound treatment 0.8353 -0.0357 -0.42 0.9778 0.0678 1.02 0.4243 0.3851 1180 BPBio1_000216 Fc1ccc(cc1)C(=O)CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J19 compound treatment 0.8735 0.00247 0.03 0.9596 0.0495 0.75 0.5474 0.7341 734 BPBio1_000217 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J20 compound treatment 0.8687 -0.00228 -0.03 0.9527 0.0427 0.64 0.4347 0.677 830 BPBio1_000218 COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J21 compound treatment 0.9446 0.0736 0.86 1.0078 0.0977 1.47 1.6491 0.9679 1281686 BPBio1_000219 COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J22 compound treatment 0.8293 -0.0417 -0.49 0.9233 0.0133 0.2 -0.2053 -0.3884 753 BPBio1_000220 O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J23 mock treatment 0.8478 -0.0232 -0.27 0.8995 -0.0106 -0.16 -0.3059 -0.9675 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 J24 mock treatment 0.8704 -5.7E-4 -0.01 0.9404 0.0303 0.46 0.3176 0.6967 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K01 compound treatment 0.9831 0.112 1.32 1.0402 0.13 1.96 2.3146 0.9813 1415 BPBio1_000221 FC(F)(F)c1cccc(c1)N2CCNCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K02 compound treatment 0.9646 0.0936 1.1 1.0627 0.153 2.29 2.4 0.9432 3560659 BPBio1_000222 O=C1CC2(CCCC2)CC(=O)N1CCCCNCC3COc4ccccc4O3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K03 compound treatment 0.9799 0.109 1.28 1.0457 0.136 2.04 2.3456 0.9746 1010605 BPBio1_000223 COP(=O)(OC)C(O)C(Cl)(Cl)Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K04 compound treatment 1.0089 0.138 1.62 1.1028 0.193 2.9 3.1935 0.9622 72 BPBio1_000224 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K05 compound treatment 1.0111 0.14 1.64 1.093 0.183 2.75 3.1081 0.9698 1019 BPBio1_000225 NC(=O)N1c2ccccc2C=Cc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K06 compound treatment 1.0184 0.147 1.73 1.1004 0.19 2.86 3.2473 0.9709 4362 BPBio1_000226 CN1CCN(CC1)C2=Nc3ccccc3Oc4ccc(Cl)cc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K07 compound treatment 0.9783 0.107 1.26 1.099 0.189 2.84 2.8994 0.933 1401 BPBio1_000227 CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K08 compound treatment 1.028 0.157 1.84 1.0879 0.178 2.67 3.1937 0.9834 3487390 BPBio1_000228 OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K09 compound treatment 0.9889 0.118 1.38 1.0764 0.166 2.5 2.7477 0.961 939 BPBio1_000229 Cc1cccc(Nc2ccccc2C(=O)O)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K10 compound treatment 0.9317 0.0607 0.71 1.0615 0.151 2.28 2.1133 0.8859 355 BPBio1_000230 COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K11 compound treatment 0.9559 0.0849 1.0 1.0767 0.167 2.51 2.4766 0.9183 3186 BPBio1_000231 CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K12 compound treatment 0.9659 0.0949 1.11 1.0501 0.14 2.11 2.2763 0.9556 1000064 BPBio1_000232 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K13 compound treatment 0.9099 0.0389 0.46 1.0423 0.132 1.99 1.7286 0.8473 920 BPBio1_000233 CCN1CCCC1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K14 compound treatment 0.9331 0.0621 0.73 1.0111 0.101 1.52 1.5891 0.9434 709 BPBio1_000234 COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K15 compound treatment 0.9147 0.0437 0.51 0.9998 0.0898 1.35 1.3169 0.9121 3127 BPBio1_000235 CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K16 compound treatment 0.9314 0.0604 0.71 0.9883 0.0782 1.18 1.3327 0.9706 3189055 BPBio1_000236 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K17 compound treatment 0.8995 0.0285 0.33 0.9665 0.0565 0.85 0.8368 0.9169 1318 BPBio1_000237 CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K18 compound treatment 0.8541 -0.0169 -0.2 0.9689 0.0588 0.88 0.4849 0.5354 1590 BPBio1_000238 CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K19 compound treatment 0.9073 0.0363 0.43 0.9878 0.0777 1.17 1.1283 0.9066 884 BPBio1_000239 CN(C)CCC(c1ccccc1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K20 compound treatment 0.8643 -0.00671 -0.08 0.9574 0.0473 0.71 0.4474 0.6251 3060388 BPBio1_000240 CO/N=C(\C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)C)/c3csc(N)n3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K21 compound treatment 0.8522 -0.0188 -0.22 0.9682 0.0581 0.87 0.4622 0.5128 965 BPBio1_000241 C(C1=NCCN1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K22 compound treatment 0.8262 -0.0448 -0.53 0.9218 0.0118 0.18 -0.2465 -0.4447 1418 BPBio1_000242 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K23 mock treatment 0.8645 -0.00649 -0.08 0.9114 0.00135 0.02 -0.0395 -0.5012 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 K24 mock treatment 0.8912 0.0202 0.24 0.9249 0.0149 0.22 0.326 0.9995 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L01 compound treatment 0.9906 0.12 1.4 1.0538 0.144 2.16 2.5209 0.9782 3561646 BPBio1_000243 COc1cc(OC)c(cc1NS(=O)(=O)c2ccc(cc2)C(F)(F)F)C(=O)CCCCN3CCC4(CC3)NC(=O)NC4=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L02 compound treatment 0.9915 0.12 1.41 1.0758 0.166 2.49 2.7621 0.9639 3177469 BPBio1_000244 NC1CCN(CC1)c2cccc(Cl)n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L03 compound treatment 0.9762 0.105 1.24 1.0797 0.17 2.55 2.6772 0.9446 347 BPBio1_000245 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L04 compound treatment 0.9971 0.126 1.48 1.0993 0.189 2.85 3.0589 0.9536 3068677 BPBio1_000246 OC1=NC(=O)CN1/N=C/c2ccc(o2)c3ccc(cc3)[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L05 compound treatment 1.04 0.169 1.98 1.1324 0.222 3.34 3.7664 0.9689 3616578 BPBio1_000247 CN1CCCN=C1/C=C/c2cccs2.O[C@H]([C@@H](O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L06 compound treatment 0.9934 0.122 1.44 1.1202 0.21 3.16 3.2503 0.9363 850 BPBio1_000248 Clc1cccc(c1)N2CCN(CCCn3nc4ccccn4c3=O)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L07 compound treatment 1.0421 0.171 2.01 1.142 0.232 3.49 3.8863 0.9656 1144 BPBio1_000249 O=C1NCC2(CCN(CCc3ccccc3)CC2)O1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L08 compound treatment 1.0439 0.173 2.03 1.1355 0.225 3.39 3.8315 0.9699 936 BPBio1_000250 OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L09 compound treatment 1.0182 0.147 1.73 1.0602 0.15 2.26 2.8181 0.9913 796 BPBio1_000251 Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L10 compound treatment 0.9974 0.126 1.48 1.0986 0.188 2.83 3.0533 0.9544 1060 BPBio1_000252 CN1CCC(=C2c3ccccc3Sc4ccccc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L11 compound treatment 0.974 0.103 1.21 1.0557 0.146 2.19 2.403 0.9608 1346 BPBio1_000253 CCN(CC)CCNC(=O)COc1ccc(OC)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L12 compound treatment 0.9501 0.0791 0.93 1.0601 0.15 2.26 2.2517 0.9229 1069 BPBio1_000254 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L13 compound treatment 0.9703 0.0993 1.17 1.0562 0.146 2.2 2.3774 0.956 1339 BPBio1_000255 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(=O)(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L14 compound treatment 0.9764 0.105 1.24 1.0235 0.113 1.71 2.0807 0.9876 1113 BPBio1_000256 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(=O)O)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L15 compound treatment 0.9488 0.0778 0.91 1.0715 0.161 2.43 2.362 0.9108 1350 BPBio1_000257 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L16 compound treatment 0.9351 0.0641 0.75 1.01 0.0999 1.5 1.5946 0.9488 3068682 BPBio1_000258 CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L17 compound treatment 0.9172 0.0462 0.54 0.9814 0.0713 1.07 1.1414 0.9501 699 BPBio1_000259 OC(=O)CCC(=O)c1ccc(cc1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L18 compound treatment 0.9017 0.0307 0.36 1.0014 0.0913 1.37 1.2257 0.8634 1348 BPBio1_000260 Clc1ccc(OCC(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L19 compound treatment 0.8698 -0.00119 -0.01 0.9553 0.0452 0.68 0.4711 0.6924 1209 BPBio1_000261 CC(C(=O)O)c1cccc(c1)C(=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L20 compound treatment 0.8676 -0.0034 -0.04 0.9654 0.0553 0.83 0.5601 0.6724 3055129 BPBio1_000262 CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@@]21C)c5ccc(cc5)N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L21 compound treatment 0.8649 -0.0061 -0.07 0.9617 0.0516 0.78 0.4986 0.6392 1127 BPBio1_000263 CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L22 compound treatment 0.8223 -0.0487 -0.57 0.9185 0.00838 0.13 -0.3154 -0.5383 1045066 BPBio1_000264 O=C(Nc1ccccc1)OCC(CN2CCCCC2)OC(=O)Nc3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L23 mock treatment 0.8554 -0.0156 -0.18 0.926 0.0159 0.24 0.0395 0.1312 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 L24 mock treatment 0.8843 0.0133 0.16 0.9417 0.0316 0.47 0.4461 0.8925 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M01 compound treatment 0.9737 0.103 1.21 1.0668 0.157 2.36 2.5188 0.9515 3060152 BPBio1_000265 OC(CN1CCN(CC1)c2cccc(Cl)c2)C(c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M02 compound treatment 0.9289 0.0579 0.68 1.0521 0.142 2.14 1.99 0.8882 3614572 BPBio1_000266 COc1ccccc1N2CCN(CCn3c(=O)n(C)c4c5ccccc5n(C)c4c3=O)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M03 compound treatment 0.9889 0.118 1.38 1.1189 0.209 3.14 3.1992 0.9322 3188938 BPBio1_000267 CN1CCCN=C1/C=C/c2sccc2C.OC(C(O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M04 compound treatment 1.0182 0.147 1.73 1.0925 0.182 2.74 3.1614 0.9752 1000056 BPBio1_000268 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M05 compound treatment 1.0548 0.184 2.16 1.146 0.236 3.55 4.0343 0.9716 3559747 BPBio1_000269 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M06 compound treatment 1.0836 0.213 2.49 1.1809 0.271 4.07 4.644 0.9723 1301 BPBio1_000270 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M07 compound treatment 1.0947 0.224 2.63 1.1614 0.251 3.78 4.5294 0.9841 110 BPBio1_000271 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M08 compound treatment 1.0841 0.213 2.5 1.0758 0.166 2.49 3.5303 1.0 1360 BPBio1_000272 Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M09 compound treatment 1.0315 0.161 1.88 1.0989 0.189 2.84 3.3399 0.9802 436 BPBio1_000273 CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M10 compound treatment 0.9825 0.111 1.31 1.0987 0.189 2.84 2.9305 0.9382 80 BPBio1_000274 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M11 compound treatment 0.9565 0.0855 1.0 1.0916 0.182 2.73 2.6403 0.9077 1002 BPBio1_000275 CN(C)CCOC(c1ccccc1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M12 compound treatment 0.9751 0.104 1.22 1.0867 0.177 2.66 2.7425 0.9379 3198950 BPBio1_000276 CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M13 compound treatment 0.9457 0.0747 0.88 1.0342 0.124 1.87 1.9392 0.9406 728 BPBio1_000277 Cc1cc(nnc1NCCN2CCOCC2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M14 compound treatment 0.984 0.113 1.33 1.0253 0.115 1.73 2.1631 0.9913 368 BPBio1_000278 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M15 compound treatment 0.9666 0.0956 1.12 1.0148 0.105 1.57 1.9072 0.9862 814 BPBio1_000279 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M16 compound treatment 0.9254 0.0544 0.64 0.9843 0.0742 1.12 1.2401 0.9649 783 BPBio1_000280 CO[C@@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]2Cc4cn(C)c5cccc1c45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M17 compound treatment 0.9378 0.0668 0.78 0.9988 0.0887 1.33 1.4977 0.9678 3471598 BPBio1_000281 CC(COc1ccccc1)NC(C)C(O)c2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M18 compound treatment 0.9112 0.0402 0.47 1.011 0.101 1.52 1.4062 0.885 2784 BPBio1_000282 C[C@@]12CC[C@H]3[C@@H](C=CC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@]1(O)CCC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M19 compound treatment 0.8927 0.0217 0.25 0.9439 0.0338 0.51 0.5395 0.9488 1223 BPBio1_000283 CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M20 compound treatment 0.8706 -3.92E-4 0.0 0.9741 0.0641 0.96 0.6779 0.7037 3189056 BPBio1_000284 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN4CCN(C)CC4)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M21 compound treatment 0.8777 0.00673 0.08 0.9474 0.0373 0.56 0.4529 0.7987 971 BPBio1_000285 CN(C(=S)Oc1ccc2ccccc2c1)c3cccc(C)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M22 compound treatment 0.8551 -0.0159 -0.19 0.9338 0.0237 0.36 0.1202 0.2988 3616513 BPBio1_000286 CN1C[C@@H](CC2[C@H]1Cc3c[nH]c4cccc2c34)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C5=O.OC(C(O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M23 mock treatment 0.8834 0.0124 0.15 0.9579 0.0478 0.72 0.6113 0.8336 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 M24 mock treatment 0.9105 0.0395 0.46 0.907 -0.00303 -0.05 0.2957 0.6345 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N01 compound treatment 1.0107 0.14 1.64 1.0917 0.182 2.73 3.0907 0.9702 3177235 BPBio1_000287 CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]3[C@H]1Cc4cn(C)c5cccc3c45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N02 compound treatment 0.9916 0.121 1.42 1.094 0.184 2.77 2.9566 0.9517 3614595 BPBio1_000288 CN(C)Cc1nc(no1)c2cn(C)c3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N03 compound treatment 1.0076 0.137 1.6 1.1066 0.197 2.96 3.2234 0.9587 747 BPBio1_000289 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCNCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N04 compound treatment 1.0526 0.182 2.13 1.1279 0.218 3.28 3.8227 0.9783 1608 BPBio1_000290 NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N2CCC[C@H]2C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N05 compound treatment 1.1412 0.27 3.17 1.1553 0.245 3.69 4.8498 0.9972 3189176 BPBio1_000291 CCCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N06 compound treatment 1.0676 0.197 2.31 1.1808 0.271 4.07 4.5108 0.9638 3068878 BPBio1_000292 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@@H]2O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N07 compound treatment 1.0885 0.217 2.55 1.2035 0.293 4.41 4.9249 0.9662 816 BPBio1_000293 Cc1cc(cc(C)c1CC2=NCCN2)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N08 compound treatment 1.134 0.263 3.09 1.1905 0.28 4.22 5.1645 0.9883 907526 BPBio1_000294 CN1CCN(CC(=O)N2c3c(C)scc3C(=O)Nc4ccccc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N09 compound treatment 1.091 0.22 2.58 1.1409 0.231 3.47 4.2806 0.9894 1181 BPBio1_000295 Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N10 compound treatment 1.0385 0.168 1.97 1.1005 0.19 2.86 3.4157 0.9832 773 BPBio1_000296 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N11 compound treatment 1.017 0.146 1.71 1.1254 0.215 3.24 3.5013 0.9558 1162 BPBio1_000297 Cc1c(NC(=O)c2cccnc2)c(=O)n(c3ccccc3)n1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N12 compound treatment 1.0103 0.139 1.64 1.1297 0.22 3.3 3.4917 0.9474 1357 BPBio1_000298 CCCCN1CCCCC1C(=O)Nc2c(C)cccc2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N13 compound treatment 1.0001 0.129 1.52 1.1107 0.201 3.02 3.2047 0.9493 812 BPBio1_000299 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N14 compound treatment 0.953 0.082 0.96 1.0028 0.0927 1.39 1.6665 0.9836 927 BPBio1_000300 CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N15 compound treatment 0.9515 0.0805 0.95 1.0228 0.113 1.69 1.8667 0.962 386963 BPBio1_000301 Clc1ccc(Cn2c(CN3CCCC3)nc4ccccc24)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N16 compound treatment 0.9883 0.117 1.38 1.026 0.116 1.74 2.2057 0.9932 876 BPBio1_000302 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N17 compound treatment 0.9069 0.0359 0.42 0.9649 0.0548 0.82 0.8805 0.9514 1075 BPBio1_000303 CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N18 compound treatment 0.9505 0.0795 0.93 1.0172 0.107 1.61 1.7989 0.9663 2117626 BPBio1_000304 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N19 compound treatment 0.9393 0.0683 0.8 0.9747 0.0646 0.97 1.2537 0.9955 1016 BPBio1_000305 CN1CCOC(c2ccccc2)c3ccccc3C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N20 compound treatment 0.9275 0.0565 0.66 0.9906 0.0805 1.21 1.3245 0.9598 467359 BPBio1_000306 CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N21 compound treatment 0.8767 0.00573 0.07 0.9347 0.0247 0.37 0.3099 0.8219 3046406 BPBio1_000307 Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N22 compound treatment 0.8803 0.00928 0.11 0.9566 0.0465 0.7 0.5714 0.8076 714 BPBio1_000308 CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc2ccc(OC)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N23 mock treatment 0.8899 0.0189 0.22 0.9321 0.022 0.33 0.3907 0.9811 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 N24 mock treatment 0.9041 0.0331 0.39 0.9443 0.0342 0.51 0.6387 0.9905 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O01 compound treatment 0.989 0.118 1.39 1.0995 0.189 2.85 2.9942 0.9451 3561713 BPBio1_000309 CC(C)(C)NC[C@H](O)COc1cccc2[nH]c(C#N)cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O02 compound treatment 0.994 0.123 1.44 1.0977 0.188 2.82 3.0165 0.9516 3614574 BPBio1_000310 COc1ccccc1N2CCN(CCn3c(=O)[nH]c4c5ccccc5[nH]c4c3=O)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O03 compound treatment 1.0413 0.17 2.0 1.1303 0.22 3.31 3.7549 0.9708 1125 BPBio1_000311 CCOC(=O)NNc1nncc2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O04 compound treatment 1.0546 0.184 2.16 1.1274 0.217 3.27 3.8354 0.9796 935 BPBio1_000312 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O05 compound treatment 1.0748 0.204 2.39 1.1196 0.21 3.15 3.9194 0.9907 1174 BPBio1_000313 CN(C)CCCN1c2ccccc2CCc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O06 compound treatment 1.1318 0.261 3.06 1.1766 0.267 4.01 4.9988 0.9912 3616516 BPBio1_000314 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@H](C)C[C@@]4(CO4)C(=O)[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O07 compound treatment 1.1177 0.247 2.9 1.2144 0.304 4.58 5.2834 0.9756 1212 BPBio1_000315 CC/1=C(CC(=O)O)c2cc(F)ccc2\C1=C/c3ccc(cc3)S(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O08 compound treatment 1.1538 0.283 3.32 1.1903 0.28 4.21 5.3273 0.993 3616519 BPBio1_000316 CCC(=O)O[C@H]1[C@H](C)O[C@H](C[C@@]1(C)O)O[C@@H]2[C@@H](C)O[C@@H](O[C@H]3[C@@H](CC=O)C[C@@H](C)[C@H](O)/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](OC(=O)CC)[C@@H]3OC)[C@H](O)[C@H]2N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O09 compound treatment 1.1204 0.249 2.93 1.1459 0.236 3.55 4.5778 0.9955 1365 BPBio1_000317 CN(C)CCC=C1c2ccccc2CCc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O10 compound treatment 1.0793 0.208 2.45 1.162 0.252 3.79 4.4077 0.9776 3616520 BPBio1_000318 CO[C@H]1[C@@H](CC(=O)O[C@H](C)C/C=C/C=C/[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(OC(=O)CC(C)C)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O11 compound treatment 1.0619 0.191 2.24 1.1204 0.21 3.16 3.8205 0.9858 872 BPBio1_000319 CCN(CC)CCOC(=O)C(c1ccccc1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O12 compound treatment 1.0832 0.212 2.49 1.1008 0.191 2.87 3.7898 0.9975 346 BPBio1_000320 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)[C@@H]4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O13 compound treatment 1.055 0.184 2.16 1.1157 0.206 3.09 3.7137 0.9846 969 BPBio1_000321 CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O14 compound treatment 1.0549 0.184 2.16 1.0826 0.173 2.59 3.3613 0.9958 3616524 BPBio1_000322 CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C/C=C(\C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O15 compound treatment 1.044 0.173 2.03 1.0825 0.172 2.59 3.2695 0.9927 2080073 BPBio1_000323 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O16 compound treatment 1.0181 0.147 1.73 1.0435 0.133 2.01 2.6402 0.9972 1257 BPBio1_000324 CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O17 compound treatment 1.001 0.13 1.53 1.0265 0.116 1.75 2.3171 0.9976 731 BPBio1_000325 CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O18 compound treatment 0.9276 0.0566 0.66 1.0558 0.146 2.19 2.0198 0.8819 1000317 BPBio1_000326 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O19 compound treatment 0.9337 0.0627 0.74 1.0081 0.098 1.47 1.5627 0.9484 1001312 BPBio1_000327 C[N+]1(C)CCC(=C(c2ccccc2)c3ccccc3)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O20 compound treatment 0.931 0.06 0.7 1.0156 0.106 1.59 1.6199 0.933 3069047 BPBio1_000328 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]3NC(=N)N)O[C@@H](C)[C@]2(O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O21 compound treatment 0.9149 0.0439 0.52 0.9955 0.0855 1.29 1.2731 0.9195 1053 BPBio1_000329 COc1cc(cc(OC)c1OC)C(=O)NCc2ccc(OCCN(C)C)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O22 compound treatment 0.9009 0.0299 0.35 1.0006 0.0905 1.36 1.2103 0.8613 3189062 BPBio1_000330 CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O)OC[C@]1(C)O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@@H](CC[C@H]3N)[C@@H](C)N)[C@@H]2O)OC[C@]1(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O23 mock treatment 0.8713 3.04E-4 0.0 0.9701 0.06 0.9 0.6402 0.7099 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 O24 mock treatment 0.9129 0.0419 0.49 0.9746 0.0645 0.97 1.0338 0.9504 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P01 compound treatment 1.0036 0.133 1.56 1.1583 0.248 3.73 3.74 0.9247 1434 BPBio1_000331 CN1CCN2C(C1)c3ccccc3Cc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P02 compound treatment 1.0209 0.15 1.76 1.1433 0.233 3.51 3.7237 0.9491 1315226 BPBio1_000332 CN1C2CCC1CC(C2)OC(=O)c3cc(C)cc(C)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P03 compound treatment 1.0142 0.143 1.68 1.1162 0.206 3.1 3.3805 0.9587 805 BPBio1_000333 CCc1cccc2c3CCOC(CC)(CC(=O)O)c3[nH]c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P04 compound treatment 0.9922 0.121 1.42 1.1233 0.213 3.21 3.2733 0.9332 3177204 BPBio1_000334 CC(C(O)c1ccc(O)cc1)N2CCC(Cc3ccccc3)CC2.OC(C(O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P05 compound treatment 1.0455 0.175 2.05 1.1128 0.203 3.05 3.6043 0.9813 3069144 BPBio1_000335 C[N+]1([O-])[C@H]2C[C@@H](C[C@@H]1[C@H]3O[C@H]32)OC(=O)[C@H](CO)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P06 compound treatment 1.1728 0.302 3.54 1.1563 0.246 3.7 5.1224 0.9998 43 BPBio1_000336 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P07 compound treatment 1.1593 0.288 3.38 1.2764 0.366 5.51 6.2876 0.9726 3616593 BPBio1_000337 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)[C@H](CO)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P08 compound treatment 1.226 0.355 4.17 1.2061 0.296 4.45 6.0939 0.9994 437 BPBio1_000338 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P09 compound treatment 1.1756 0.305 3.57 1.1881 0.278 4.18 5.4843 0.997 3487401 BPBio1_000339 NC(=O)OCC(O)COc1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P10 compound treatment 1.1784 0.307 3.61 1.1702 0.26 3.91 5.3177 0.9992 1036 BPBio1_000340 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P11 compound treatment 1.1243 0.253 2.97 1.1856 0.276 4.14 5.0322 0.9867 3189177 BPBio1_000341 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N=C)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P12 compound treatment 1.1215 0.251 2.94 1.1633 0.253 3.81 4.7715 0.9918 3616642 BPBio1_000342 CN(C)[C@@H]1C2CC3Cc4c(ccc(O)c4C(=O)C3=C(O)[C@@]2(O)C(=O)C(=C1O)C(=O)N)N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P13 compound treatment 1.1136 0.243 2.85 1.1222 0.212 3.19 4.2688 0.9984 2997 BPBio1_000343 COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P14 compound treatment 1.0812 0.21 2.47 1.1141 0.204 3.07 3.9143 0.9942 74 BPBio1_000344 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P15 compound treatment 1.0703 0.199 2.34 1.0628 0.153 2.3 3.278 1.0 1323 BPBio1_000345 CC1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P16 compound treatment 1.082 0.211 2.48 1.0151 0.105 1.58 2.8676 0.9764 3055 BPBio1_000346 NC(=N)NCCN1CCCCCCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P17 compound treatment 1.0444 0.173 2.03 1.055 0.145 2.18 2.9803 0.9994 999 BPBio1_000347 CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P18 compound treatment 1.0234 0.152 1.79 1.0824 0.172 2.59 3.0973 0.9836 763 BPBio1_000348 CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P19 compound treatment 0.9834 0.112 1.32 1.0 0.0899 1.35 1.8885 0.9999 1443 BPBio1_000349 CN(C)CCOC(c1ccccc1)c2ccccc2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P20 compound treatment 0.9905 0.119 1.4 0.9776 0.0676 1.02 1.7101 0.9875 907228 BPBio1_000350 CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P21 compound treatment 0.9562 0.0852 1.0 1.0124 0.102 1.54 1.7952 0.9782 1291 BPBio1_000351 CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)c1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P22 compound treatment 0.8983 0.0273 0.32 0.9863 0.0762 1.15 1.0375 0.8715 1130 BPBio1_000352 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P23 mock treatment 0.9252 0.0542 0.64 1.032 0.122 1.83 1.7461 0.8999 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2320 P24 mock treatment 0.9007 0.0297 0.35 1.0198 0.11 1.65 1.4136 0.838 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A01 compound treatment 1.116 0.198 2.32 0.9668 0.158 2.37 3.3163 0.9999 3614601 BPBio1_000353 CC(C)n1cnc2c(cc(Cl)cc12)C(=O)N[C@H]3CN4CCC3CC4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A02 compound treatment 1.0149 0.0966 1.13 0.9476 0.138 2.08 2.2736 0.9592 1095093 BPBio1_000354 CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A03 compound treatment 1.0375 0.119 1.4 0.9763 0.167 2.51 2.7659 0.9618 3189183 BPBio1_000355 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]3NC(=N)N)O[C@@H](C)[C@]2(O)C=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A04 compound treatment 1.0371 0.119 1.39 0.9652 0.156 2.35 2.645 0.9691 2717 BPBio1_000356 CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A05 compound treatment 1.0566 0.138 1.62 0.9473 0.138 2.08 2.6169 0.9926 3480229 BPBio1_000357 COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A06 compound treatment 0.9886 0.0703 0.83 0.9745 0.165 2.49 2.3411 0.8939 1403 BPBio1_000358 COC(=O)C1=CCCN(C)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A07 compound treatment 0.9899 0.0716 0.84 0.9932 0.184 2.77 2.5515 0.8821 1132 BPBio1_000359 CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A08 compound treatment 0.9923 0.074 0.87 0.9736 0.164 2.47 2.3621 0.9014 1000219 BPBio1_000360 N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A09 compound treatment 0.9743 0.056 0.66 0.955 0.146 2.19 2.0151 0.8803 1001994 BPBio1_000361 C[C@@H](N)[C@@H](O)c1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A10 compound treatment 0.9746 0.0563 0.66 0.9559 0.147 2.21 2.0274 0.8802 1000243 BPBio1_000362 CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A11 compound treatment 0.9482 0.0299 0.35 0.9026 0.0934 1.4 1.2409 0.8574 1000341 BPBio1_000363 OC[C@H](O)[C@H]1OC(=O)C(=C1O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A12 compound treatment 1.0013 0.0829 0.97 0.9089 0.0998 1.5 1.7492 0.9781 387 BPBio1_000364 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A13 compound treatment 1.0334 0.115 1.35 0.9155 0.106 1.6 2.0861 0.9965 800 BPBio1_000365 C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A14 compound treatment 0.9803 0.062 0.73 0.9331 0.124 1.86 1.8317 0.9158 3068973 BPBio1_000366 C(CN1CCOCC1)Nc2cc3CCCc4ccccc4-c3nn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A15 compound treatment 0.968 0.0497 0.58 0.9696 0.16 2.41 2.1181 0.8534 3063 BPBio1_000367 CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A16 compound treatment 0.9639 0.0456 0.54 1.0022 0.193 2.9 2.4313 0.8236 1000308 BPBio1_000368 N[C@]1(C[C@@H]2C[C@H]3C[C@@H](C2)C1)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A17 compound treatment 0.9602 0.0419 0.49 0.9331 0.124 1.86 1.6658 0.8642 3173242 BPBio1_000369 Nc1nc2cc(Cl)ccc2o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A18 compound treatment 0.9714 0.0531 0.62 0.9381 0.129 1.94 1.8122 0.8896 3068976 BPBio1_000370 Clc1ccc(CCC(Cn2ccnc2)Sc3c(Cl)cccc3Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A19 compound treatment 0.935 0.0167 0.2 0.9319 0.123 1.85 1.4433 0.7777 1516 BPBio1_000371 Nc1c2CCCCc2nc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A20 compound treatment 0.9562 0.0379 0.44 0.8891 0.08 1.2 1.1648 0.9085 26 BPBio1_000372 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A21 compound treatment 0.9656 0.0473 0.55 0.8611 0.0519 0.78 0.9446 0.986 3487402 BPBio1_000373 CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A22 compound treatment 0.9584 0.0401 0.47 0.8188 0.0096 0.14 0.4347 0.8834 3616687 BPBio1_000374 C[C@H]1O[C@@H](O[C@@H]/2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(=O)O)C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C2)[C@@H](O)[C@@H](N)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A23 mock treatment 0.9739 0.0556 0.65 0.817 0.00783 0.12 0.5447 0.8215 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 A24 mock treatment 0.9673 0.049 0.58 0.8121 0.0029 0.04 0.4376 0.7585 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B01 compound treatment 1.0578 0.139 1.64 0.9867 0.177 2.67 3.045 0.9725 1001998 BPBio1_000375 Nc1ccc(CCN2CCN(CC2)c3cccc(c3)C(F)(F)F)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B02 compound treatment 1.0701 0.152 1.78 0.9787 0.17 2.55 3.0627 0.9846 907126 BPBio1_000376 NC/C=C\C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B03 compound treatment 1.0259 0.108 1.26 0.9628 0.154 2.31 2.5268 0.9596 429 BPBio1_000377 NCCc1c[nH]c2ccc(O)cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B04 compound treatment 1.0271 0.109 1.28 0.9685 0.159 2.4 2.597 0.9567 3189566 BPBio1_000378 COc1cc2CC[N+](C)(C)[C@@H]3Cc4ccc(O)c(Oc5cc6[C@H](Cc7cccc(Oc(c1O)c32)c7)N(C)CCc6cc5OC)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B05 compound treatment 1.0007 0.0824 0.97 0.9566 0.147 2.22 2.2517 0.9308 1000242 BPBio1_000379 CN(C)CCn1nnnc1SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4csc(N)n4)C3=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B06 compound treatment 1.0057 0.0873 1.03 0.954 0.145 2.18 2.2646 0.9409 907285 BPBio1_000380 CC(C)[C@@]1(NC(=O)[C@@H]2C[C@H]3[C@@H](Cc4c[nH]c5cccc3c45)N(C)C2)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B07 compound treatment 0.9719 0.0536 0.63 0.9268 0.118 1.77 1.6951 0.9032 3189438 BPBio1_000381 Cc1n[nH]c(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B08 compound treatment 0.9817 0.0634 0.74 0.9751 0.166 2.5 2.2907 0.8796 961 BPBio1_000382 COc1ccc2[C@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5c(OC)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B09 compound treatment 0.9362 0.0179 0.21 0.973 0.164 2.46 1.8907 0.7646 1077918 BPBio1_000383 Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B10 compound treatment 0.9679 0.0496 0.58 0.9169 0.108 1.62 1.5571 0.9047 3616747 BPBio1_000384 CCOC(=O)Oc1c(OC)cc(cc1OC)C(=O)O[C@@H]2C[C@@H]3CN4CCc5c([nH]c6cc(OC)ccc56)[C@H]4C[C@@H]3[C@@H]([C@H]2OC)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B11 compound treatment 0.9777 0.0594 0.7 0.889 0.0798 1.2 1.3419 0.9665 3173761 BPBio1_000385 N[C@@H](C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B12 compound treatment 0.9917 0.0734 0.86 0.8775 0.0683 1.03 1.3352 0.9962 1000124 BPBio1_000386 CN1C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B13 compound treatment 1.0298 0.111 1.31 0.8827 0.0735 1.11 1.7074 0.9965 3189439 BPBio1_000387 CC(C)CCCCC(=O)N[C@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H](CCN)C(=O)N[C@@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@@H](CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)C(C)C)[C@@H](C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B14 compound treatment 0.955 0.0367 0.43 0.8896 0.0804 1.21 1.1598 0.9033 976 BPBio1_000388 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B15 compound treatment 1.0023 0.084 0.99 0.9419 0.133 2.0 2.1079 0.9471 3587 BPBio1_000389 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B16 compound treatment 0.9397 0.0214 0.25 0.9062 0.097 1.46 1.209 0.8168 3189567 BPBio1_000390 CCN1C[C@@]2(COC)C3[C@@H](OC)[C@H]4[C@@H]1[C@@]3(C5C[C@@]6(O)[C@H](OC(=O)c7ccccc7)C5[C@]4(OC(=O)C)[C@@H](O)[C@H]6OC)[C@H](C[C@H]2O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B17 compound treatment 0.9517 0.0334 0.39 0.8897 0.0805 1.21 1.1332 0.8903 3616733 BPBio1_000391 CN(C)CC/C=C/1\c2ccccc2CSc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B18 compound treatment 0.9416 0.0233 0.27 0.8869 0.0777 1.17 1.0195 0.8494 3141 BPBio1_000392 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)/C=C/c6cc(OC)c(OC)c(OC)c6 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B19 compound treatment 0.9123 -0.00603 -0.07 0.8646 0.0555 0.83 0.5397 0.6448 3616734 BPBio1_000393 CC(C)(O/N=C(\C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)C[n+]3ccccc3)/c4csc(N)n4)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B20 compound treatment 0.9396 0.0212 0.25 0.8529 0.0437 0.66 0.6414 0.9118 3068781 BPBio1_000394 CC(C)[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B21 compound treatment 0.9407 0.0224 0.26 0.8463 0.0371 0.56 0.5805 0.9408 3060173 BPBio1_000395 NC(=N)NCc1cccc(I)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B22 compound treatment 0.9971 0.0788 0.92 0.958 0.149 2.24 2.2367 0.9235 2081037 BPBio1_000396 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(OC)c(OC)cc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B23 mock treatment 0.9055 -0.0128 -0.15 0.8017 -0.00744 -0.11 -0.1856 -0.9893 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 B24 mock treatment 0.9341 0.0158 0.19 0.818 0.0088 0.13 0.2248 0.9862 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C01 compound treatment 1.0427 0.124 1.46 0.9995 0.19 2.86 3.0569 0.9512 1444554 BPBio1_000397 C(N1CCN(CC1)c2nc3ccccc3s2)c4ccc5OCOc5c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C02 compound treatment 1.0709 0.153 1.79 0.9695 0.16 2.41 2.9714 0.9893 417 BPBio1_000398 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C03 compound treatment 1.0659 0.148 1.73 0.9505 0.141 2.13 2.7279 0.9949 907527 BPBio1_000399 C(C#CCN1CCCC1)N2CCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C04 compound treatment 1.024 0.106 1.24 0.9252 0.116 1.74 2.1102 0.986 3189308 BPBio1_000400 C[C@@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C05 compound treatment 1.0188 0.101 1.18 0.976 0.167 2.51 2.6085 0.9408 1486 BPBio1_000401 CC(C)NCC(O)COc1ccc(NC(=O)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C06 compound treatment 0.9927 0.0744 0.87 0.9625 0.153 2.31 2.2482 0.9118 336 BPBio1_000402 COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(=O)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C07 compound treatment 0.9959 0.0776 0.91 0.944 0.135 2.03 2.0776 0.9347 1142 BPBio1_000403 Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C08 compound treatment 0.974 0.0557 0.65 0.9503 0.141 2.12 1.9629 0.884 1023517 BPBio1_000404 NC(=O)Nc1ccc(cc1)[As](=O)(O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C09 compound treatment 0.9685 0.0502 0.59 0.9543 0.145 2.18 1.96 0.8668 1192 BPBio1_000405 Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C10 compound treatment 0.9531 0.0348 0.41 0.9353 0.126 1.9 1.6303 0.8401 360 BPBio1_000406 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C11 compound treatment 1.0115 0.0932 1.09 0.9033 0.0941 1.42 1.7741 0.9919 3068881 BPBio1_000407 CCCOc1ccccc1c2nc(=O)c3[nH]nnc3[nH]2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C12 compound treatment 0.9999 0.0816 0.96 0.8955 0.0863 1.3 1.5945 0.9888 2060483 BPBio1_000408 CC(=O)N[C@@H](CC(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C13 compound treatment 0.9787 0.0604 0.71 0.9014 0.0923 1.39 1.4826 0.9515 1471 BPBio1_000409 CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C14 compound treatment 0.9569 0.0386 0.45 0.9087 0.0995 1.5 1.3786 0.8815 3189309 BPBio1_000410 CCOC(=O)OC(C)OC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](NC(=O)[C@H](N)c3ccccc3)C2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C15 compound treatment 0.9441 0.0258 0.3 0.933 0.124 1.86 1.5304 0.8114 2431 BPBio1_000411 CCN(CC)CCNC(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C16 compound treatment 0.8937 -0.0247 -0.29 0.9166 0.107 1.62 0.9382 0.5714 1960 BPBio1_000412 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C17 compound treatment 0.9217 0.00335 0.04 0.9464 0.137 2.06 1.4873 0.7205 3189186 BPBio1_000413 CNc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C18 compound treatment 0.89 -0.0283 -0.33 0.9097 0.101 1.51 0.8339 0.5388 951 BPBio1_000414 OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C19 compound treatment 0.9119 -0.00644 -0.08 0.8948 0.0856 1.29 0.8568 0.6645 3368 BPBio1_000415 NC(=N)NC(=O)Cc1c(Cl)cccc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C20 compound treatment 0.9237 0.00539 0.06 0.864 0.0548 0.82 0.6272 0.7592 982 BPBio1_000416 CC(=O)Oc1ccc(cc1)C(c2ccc(OC(=O)C)cc2)c3ccccn3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C21 compound treatment 0.9162 -0.00207 -0.02 0.8598 0.0507 0.76 0.5216 0.6842 1001939 BPBio1_000417 OCCN1CCN(CC/C=C\2/c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C22 compound treatment 0.8874 -0.0309 -0.36 0.8097 4.93E-4 0.01 -0.251 -0.6925 3557442 BPBio1_000418 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)CCC3=C)\CCC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C23 mock treatment 0.9092 -0.00909 -0.11 0.8016 -0.00761 -0.11 -0.1563 -0.9994 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 C24 mock treatment 0.9358 0.0174 0.2 0.784 -0.0252 -0.38 -0.1232 -0.286 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D01 compound treatment 1.0702 0.152 1.78 0.9607 0.152 2.28 2.8721 0.9926 1181 BPBio1_000419 Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D02 compound treatment 1.0402 0.122 1.43 0.9472 0.138 2.08 2.4799 0.9835 864 BPBio1_000420 Oc1noc2CNCCc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D03 compound treatment 1.0259 0.108 1.26 0.94 0.131 1.97 2.2845 0.977 2120971 BPBio1_000421 CN1CCCC(CC2c3ccccc3Sc4ccccc24)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D04 compound treatment 1.0463 0.128 1.5 0.947 0.138 2.07 2.5277 0.9875 1218 BPBio1_000422 CCCCNc1ccc(cc1)C(=O)OCCN(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D05 compound treatment 0.9954 0.0771 0.91 0.9489 0.14 2.1 2.1262 0.9291 3172716 BPBio1_000423 NC(=O)N/N=C/c1ccc(o1)[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D06 compound treatment 0.859 -0.0593 -0.7 0.7946 -0.0146 -0.22 -0.6471 -0.8872 1000293 BPBio1_000424 C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D07 compound treatment 0.9615 0.0432 0.51 0.9493 0.14 2.11 1.8484 0.853 1782 BPBio1_000425 COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D08 compound treatment 0.9764 0.0581 0.68 0.9801 0.171 2.57 2.299 0.8647 3198963 BPBio1_000426 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)O[C@]61CC[C@H](C)CN6 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D09 compound treatment 0.9569 0.0386 0.45 0.9358 0.127 1.9 1.6673 0.8516 912 BPBio1_000427 CCCc1cc(=O)[nH]c(=S)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D10 compound treatment 0.9827 0.0644 0.76 0.9214 0.112 1.69 1.7272 0.9343 964 BPBio1_000428 CN(C)N=Nc1[nH]cnc1C(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D11 compound treatment 1.0003 0.082 0.96 0.9058 0.0967 1.45 1.7084 0.9799 3616735 BPBio1_000429 CC(C)N1CCN(CC1)c2ccc(OC[C@H]3CO[C@@](Cn4cncn4)(O3)c5ccc(Cl)cc5Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D12 compound treatment 0.9995 0.0812 0.95 0.8642 0.055 0.83 1.2585 0.9975 3616748 BPBio1_000430 CC(C)[N+]1(C)[C@@H]2CC[C@@H]1CC(C2)OC(=O)C(CO)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D13 compound treatment 0.993 0.0747 0.88 0.851 0.0418 0.63 1.065 0.9867 3487464 BPBio1_000431 CC(C(=O)O)c1ccc(s1)C(=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D14 compound treatment 0.9347 0.0163 0.19 0.8772 0.068 1.02 0.8587 0.8254 1092107 BPBio1_000432 CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D15 compound treatment 0.9259 0.0076 0.09 0.8687 0.0595 0.89 0.6959 0.7737 3616736 BPBio1_000433 CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]6NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(=O)N)NC1=O)c7ccc(O)c(c7)-c8c(O)cc(O)cc8[C@H](NC6=O)C(=O)O)c3O[C@@H]9OC(CO)[C@@H](O)[C@H](O)[C@H]9O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)c(Cl)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D16 compound treatment 0.9521 0.0337 0.4 0.8845 0.0753 1.13 1.0806 0.901 1000115 BPBio1_000434 COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D17 compound treatment 0.935 0.0167 0.2 0.9652 0.156 2.35 1.7982 0.7636 1263 BPBio1_000435 C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D18 compound treatment 0.899 -0.0193 -0.23 0.8543 0.0451 0.68 0.319 0.4463 450 BPBio1_000436 COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D19 compound treatment 0.8779 -0.0404 -0.47 0.8398 0.0307 0.46 -0.0094 -0.0142 1489 BPBio1_000437 CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D20 compound treatment 0.8744 -0.044 -0.52 0.8259 0.0167 0.25 -0.187 -0.3258 1084508 BPBio1_000438 COc1ccc2cc3-c4cc(OC)c(OC)cc4CC[n+]3cc2c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D21 compound treatment 0.902 -0.0163 -0.19 0.842 0.0328 0.49 0.2132 0.4027 1113307 BPBio1_000439 CCN(CC)C(=O)c1ccc(O)c(OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D22 compound treatment 0.9449 0.0266 0.31 0.818 0.00884 0.13 0.3148 0.9276 3616749 BPBio1_000440 COc1cc2CC[C@H](N)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D23 mock treatment 0.8838 -0.0345 -0.41 0.8033 -0.00591 -0.09 -0.3495 -0.842 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 D24 mock treatment 0.9635 0.0452 0.53 0.7536 -0.0556 -0.84 -0.2163 -0.2184 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E01 compound treatment 1.0926 0.174 2.05 1.0299 0.221 3.32 3.7938 0.973 3561656 BPBio1_000441 CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E02 compound treatment 1.0957 0.177 2.08 0.9975 0.188 2.83 3.4752 0.9885 991 BPBio1_000442 CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E03 compound treatment 1.0933 0.175 2.05 1.015 0.206 3.1 3.6413 0.9801 1188 BPBio1_000443 NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E04 compound treatment 1.064 0.146 1.71 0.9794 0.17 2.56 3.0196 0.9808 3616694 BPBio1_000444 CCCCCCCCN[C@H](C)[C@@H](O)c1ccc(SC(C)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E05 compound treatment 1.0504 0.132 1.55 0.9909 0.182 2.73 3.0288 0.9639 1510 BPBio1_000445 CN(C)CCN(Cc1cccs1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E06 compound treatment 1.0361 0.118 1.38 0.9629 0.154 2.31 2.6115 0.9698 3069011 BPBio1_000446 NCCC(=O)NCCc1c[nH]cn1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E07 compound treatment 1.0051 0.0868 1.02 0.9338 0.125 1.87 2.0458 0.959 844 BPBio1_000447 CNCCCN1c2ccccc2CCc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E08 compound treatment 1.0384 0.12 1.41 0.9368 0.128 1.92 2.3544 0.9885 1409 BPBio1_000448 CCCC(C)(COC(=O)N)COC(=O)NC(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E09 compound treatment 1.0168 0.0985 1.16 0.9472 0.138 2.08 2.2844 0.9618 2203 BPBio1_000449 CN(CCCOc1ccc(Cl)cc1Cl)CC#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E10 compound treatment 0.9748 0.0565 0.66 0.9394 0.13 1.96 1.8534 0.8964 3189311 BPBio1_000450 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](N)C2=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E11 compound treatment 0.9697 0.0514 0.6 0.9335 0.124 1.87 1.749 0.8901 1390 BPBio1_000451 CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E12 compound treatment 0.9993 0.081 0.95 0.9134 0.104 1.57 1.7798 0.9713 2117409 BPBio1_000452 COc1cc(ccc1N=Nc2ccc3c(cc(c(N)c3c2O)S(=O)(=O)O)S(=O)(=O)O)c4ccc(N=Nc5ccc6c(cc(c(N)c6c5O)S(=O)(=O)O)S(=O)(=O)O)c(OC)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E13 compound treatment 0.9702 0.0519 0.61 0.8858 0.0766 1.15 1.2458 0.9555 1000329 BPBio1_000453 CNCCC[C@]1(CC[C@H]2c3ccccc31)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E14 compound treatment 0.9778 0.0595 0.7 0.9106 0.101 1.52 1.5717 0.9373 907205 BPBio1_000454 COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E15 compound treatment 0.9525 0.0342 0.4 0.9171 0.108 1.62 1.4315 0.8561 3189187 BPBio1_000455 Nc1nc(S)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E16 compound treatment 0.909 -0.00935 -0.11 0.9397 0.131 1.96 1.3104 0.6665 3173763 BPBio1_000456 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E17 compound treatment 0.9016 -0.0167 -0.2 0.9164 0.107 1.61 1.0018 0.6165 801 BPBio1_000457 CN(C)CC/C=C/1\c2ccccc2Sc3ccc(Cl)cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E18 compound treatment 0.8651 -0.0532 -0.62 1.0607 0.252 3.78 2.2334 0.5825 3180147 BPBio1_000458 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(O)c(OC)cc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E19 compound treatment 0.907 -0.0113 -0.13 0.9236 0.114 1.72 1.1224 0.6505 1000292 BPBio1_000459 C[C@H](NCCc1ccc(O)cc1)[C@H](O)c2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E20 compound treatment 0.8787 -0.0396 -0.46 0.8559 0.0467 0.7 0.1682 0.1996 2838 BPBio1_000460 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E21 compound treatment 0.9238 0.00548 0.06 0.8753 0.0661 0.99 0.7487 0.7513 417 BPBio1_000461 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E22 compound treatment 0.9107 -0.00762 -0.09 0.8227 0.0135 0.2 0.0807 0.3629 3616697 BPBio1_000462 CO[C@@H]1CN(CCCOc2ccc(F)cc2)CC[C@@H]1NC(=O)c3cc(Cl)c(N)cc3OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E23 mock treatment 0.8914 -0.0269 -0.32 0.8171 0.00794 0.12 -0.1388 -0.4112 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 E24 mock treatment 0.9789 0.0606 0.71 0.8173 0.00811 0.12 0.5889 0.8165 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F01 compound treatment 1.0801 0.162 1.9 0.9815 0.172 2.59 3.1749 0.9883 920 BPBio1_000463 CCN1CCCC1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F02 compound treatment 1.1065 0.188 2.21 0.9915 0.182 2.74 3.5004 0.9942 907532 BPBio1_000464 CP(=O)(O)C1=CCNCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F03 compound treatment 1.0421 0.124 1.45 0.9508 0.142 2.13 2.5334 0.9826 1002022 BPBio1_000465 NC(CCC(=O)O)C=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F04 compound treatment 1.0586 0.14 1.65 0.9512 0.142 2.14 2.675 0.9917 3180327 BPBio1_000466 COc1ccc2[C@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5cc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F05 compound treatment 1.0513 0.133 1.56 0.931 0.122 1.83 2.3995 0.9968 3616738 BPBio1_000467 OC(CCN1CCCCC1)(C2C[C@H]3C[C@@H]2C=C3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F06 compound treatment 1.052 0.134 1.57 0.9362 0.127 1.91 2.4602 0.9952 1054667 BPBio1_000468 CN1C(CC(O)c2ccccc2)CCCC1CC(O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F07 compound treatment 1.0074 0.0891 1.05 0.9706 0.161 2.43 2.4558 0.9292 3487465 BPBio1_000469 OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F08 compound treatment 1.009 0.0907 1.06 0.9298 0.121 1.81 2.0351 0.9677 959 BPBio1_000470 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F09 compound treatment 1.0247 0.106 1.25 0.9455 0.136 2.05 2.3331 0.9717 3189442 BPBio1_000471 CCc1cccc(CC)c1NC(=O)CN(CC(=O)O)CC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F10 compound treatment 0.9796 0.0613 0.72 0.9208 0.112 1.68 1.6949 0.9284 3000363 BPBio1_000472 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F11 compound treatment 1.0111 0.0928 1.09 0.9131 0.104 1.56 1.8753 0.9845 1252 BPBio1_000473 CC(C)NCC(O)c1cc(O)cc(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F12 compound treatment 0.9836 0.0653 0.77 0.8882 0.079 1.19 1.3823 0.9775 3061052 BPBio1_000474 CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F13 compound treatment 0.9963 0.078 0.91 0.882 0.0729 1.1 1.4218 0.996 3616739 BPBio1_000475 CN[C@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](OC3OC(=CCC3N)CN)[C@@H]2O)OC[C@@]1(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F14 compound treatment 0.97 0.0516 0.61 0.8867 0.0776 1.17 1.2534 0.9535 909 BPBio1_000476 COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F15 compound treatment 0.9369 0.0186 0.22 0.8667 0.0576 0.87 0.7664 0.8584 353 BPBio1_000477 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F16 compound treatment 1.012 0.0936 1.1 0.892 0.0829 1.25 1.6582 0.998 3189572 BPBio1_000478 CN1Cc2c3OCOc3ccc2[C@H]4[C@@H](O)Cc5cc6OCOc6cc5[C@H]41 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F17 compound treatment 0.9084 -0.00994 -0.12 0.8751 0.0659 0.99 0.618 0.6195 2269 BPBio1_000479 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F18 compound treatment 0.8872 -0.0311 -0.36 0.8665 0.0573 0.86 0.3517 0.3757 1202 BPBio1_000480 COc1ccc2CN(C)CC[C@]34C=C[C@H](O)C[C@@H]4Oc1c23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F19 compound treatment 0.9056 -0.0127 -0.15 0.8169 0.00769 0.12 -0.0238 -0.1261 2922 BPBio1_000481 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Br)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F20 compound treatment 0.9025 -0.0158 -0.19 0.7974 -0.0118 -0.18 -0.2566 -0.9998 1220 BPBio1_000482 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F21 compound treatment 0.9124 -0.00593 -0.07 0.7856 -0.0236 -0.35 -0.3001 -0.8299 1000807 BPBio1_000483 CN1CCN(CC1)C(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F22 compound treatment 0.8821 -0.0362 -0.43 0.8058 -0.00337 -0.05 -0.3365 -0.7857 3173993 BPBio1_000484 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F23 mock treatment 0.9061 -0.0122 -0.14 0.7758 -0.0333 -0.5 -0.4562 -0.8746 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 F24 mock treatment 0.9533 0.035 0.41 0.8108 0.00163 0.02 0.3076 0.7481 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G01 compound treatment 1.1148 0.196 2.31 1.0039 0.195 2.93 3.7013 0.993 3561657 BPBio1_000485 COc1cc(N)c(Cl)cc1C(=O)CCC2CCN(CCNS(=O)(=O)C)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G02 compound treatment 1.1006 0.182 2.14 1.0066 0.197 2.97 3.6119 0.9871 3314 BPBio1_000486 CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G03 compound treatment 1.0547 0.136 1.6 1.0123 0.203 3.05 3.2914 0.9545 1332 BPBio1_000487 NS(=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G04 compound treatment 1.0558 0.137 1.61 0.9754 0.166 2.5 2.9088 0.9775 1055132 BPBio1_000488 COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G05 compound treatment 1.1068 0.188 2.21 0.9836 0.174 2.62 3.4185 0.9964 3480458 BPBio1_000489 CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G06 compound treatment 1.0453 0.127 1.49 0.9396 0.13 1.96 2.4411 0.9908 3054850 BPBio1_000490 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G07 compound treatment 1.0359 0.118 1.38 0.9429 0.134 2.01 2.3975 0.9832 1048 BPBio1_000491 CCn1cc(C(=O)O)c(=O)c2cc(F)c(nc12)N3CCNCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G08 compound treatment 1.0183 0.1 1.17 0.9395 0.13 1.96 2.2151 0.97 3189313 BPBio1_000492 C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(=O)N)[C@H]2N=C1/C(=C/3\N=C(/C=C/4\N=C(/C(=C\5/[C@@H](CCC(=O)N)[C@](C)(CC(=O)N)[C@@]2(C)N5[Co+]C#N)/C)\[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)\C(C)(C)[C@@H]3CCC(=O)N)/C)OP(=O)(O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G09 compound treatment 1.0517 0.133 1.57 0.9459 0.137 2.06 2.5611 0.991 3616658 BPBio1_000493 C[C@H]1CCC[C@@H](C)N1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G10 compound treatment 1.0179 0.0996 1.17 0.9517 0.143 2.14 2.3418 0.9593 1037 BPBio1_000494 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G11 compound treatment 1.1241 0.206 2.42 1.0269 0.218 3.27 4.0229 0.9888 1105 BPBio1_000495 CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G12 compound treatment 0.9863 0.068 0.8 0.9511 0.142 2.13 2.0726 0.9099 3069049 BPBio1_000496 CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C/C=C/C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G13 compound treatment 0.9737 0.0554 0.65 0.8956 0.0864 1.3 1.3788 0.9487 3068883 BPBio1_000497 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G14 compound treatment 0.9979 0.0796 0.93 0.9695 0.16 2.41 2.3649 0.9148 3189314 BPBio1_000498 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1C5=CC(=O)OC5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G15 compound treatment 0.9097 -0.00864 -0.1 0.901 0.0919 1.38 0.9051 0.6534 3189189 BPBio1_000499 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G16 compound treatment 0.9813 0.063 0.74 0.9725 0.163 2.46 2.2592 0.8809 3189315 BPBio1_000500 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G17 compound treatment 0.892 -0.0263 -0.31 0.8943 0.0851 1.28 0.6866 0.5214 1000342 BPBio1_000501 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccccc3)C2=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G18 compound treatment 0.9738 0.0555 0.65 0.9503 0.141 2.12 1.9609 0.8835 1000279 BPBio1_000502 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G19 compound treatment 0.8787 -0.0397 -0.47 0.8764 0.0672 1.01 0.3859 0.3467 1000343 BPBio1_000503 COc1ccc2C[C@H]3[C@H]4CCCC[C@@]4(CCN3C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G20 compound treatment 0.8631 -0.0552 -0.65 0.8078 -0.00136 -0.02 -0.4724 -0.729 3069053 BPBio1_000504 CCOC(=O)n1ccn(C)c1=S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G21 compound treatment 0.8827 -0.0357 -0.42 0.8177 0.00854 0.13 -0.2051 -0.4686 764 BPBio1_000505 Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)n3c(=O)[nH]c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G22 compound treatment 0.8717 -0.0466 -0.55 0.7924 -0.0168 -0.25 -0.5653 -0.9384 1001924 BPBio1_000506 C[C@@]12CC[C@H]3[C@@H](CC[C@H]4C[C@@H](O)CC[C@@]43C)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G23 mock treatment 0.902 -0.0163 -0.19 0.7975 -0.0117 -0.18 -0.2602 -0.9991 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 G24 mock treatment 0.949 0.0307 0.36 0.8024 -0.00676 -0.1 0.1825 0.4881 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H01 compound treatment 1.1136 0.195 2.29 1.0093 0.2 3.01 3.7483 0.991 907371 BPBio1_000507 CN1C2CCC1CC(C2)NC(=O)c3nn(C)c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H02 compound treatment 1.1034 0.185 2.17 0.969 0.16 2.4 3.2352 0.9987 3560375 BPBio1_000508 CCOC(OCC)P(=O)(O)CCCN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H03 compound treatment 1.0812 0.163 1.91 0.9415 0.132 1.99 2.7594 0.9998 1095093 BPBio1_000509 CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H04 compound treatment 1.0874 0.169 1.98 0.9618 0.153 2.3 3.0268 0.9974 1000946 BPBio1_000510 COc1ccc(CC2N(C)CCc3cc(OC)c(OC)cc23)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H05 compound treatment 1.0482 0.13 1.52 0.9565 0.147 2.22 2.6439 0.9834 2141046 BPBio1_000511 CC(=O)N(CC(O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H06 compound treatment 1.0765 0.158 1.86 0.9323 0.123 1.85 2.6217 1.0 3054974 BPBio1_000512 COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H07 compound treatment 1.0823 0.164 1.92 0.9417 0.133 1.99 2.77 0.9998 3068692 BPBio1_000513 CNCCC=C1c2ccccc2C=Cc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H08 compound treatment 1.0651 0.147 1.72 0.9401 0.131 1.97 2.6108 0.9978 4895 BPBio1_000514 C[n+]1cccc(c1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H09 compound treatment 1.0425 0.124 1.46 0.9007 0.0916 1.38 2.0047 0.9996 889 BPBio1_000515 NC(=O)c1cnccn1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H10 compound treatment 1.0127 0.0944 1.11 0.9079 0.0987 1.48 1.8325 0.9896 915 BPBio1_000516 OC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H11 compound treatment 1.014 0.0957 1.12 0.8961 0.0869 1.31 1.7185 0.9972 2900 BPBio1_000517 CN1C(=O)OC(C)(C)C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H12 compound treatment 0.9791 0.0608 0.71 0.8829 0.0737 1.11 1.2887 0.9773 3616751 BPBio1_000518 CN1CC[C@]23[C@@H]4Nc5ccccc5[C@]3(CCN4C)[C@@H]1Nc6ccccc62 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H13 compound treatment 0.9809 0.0626 0.74 0.8635 0.0544 0.82 1.0979 0.9986 1607 BPBio1_000519 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H14 compound treatment 0.9687 0.0504 0.59 0.8556 0.0464 0.7 0.9121 0.9966 3616752 BPBio1_000520 COc1ccc(cc1OC)C(=O)OC2C[C@H]3CC[C@H](C2)N3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H15 compound treatment 0.9257 0.00742 0.09 0.8486 0.0394 0.59 0.481 0.8023 3616740 BPBio1_000521 C[C@H]1O[C@@H](OC/2CC(O)C(C(O)CC(=O)CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)OC(C)C(C)C(O)C(C)/C=C/C=C/CC\C=C\C=C\C=C\C=C2)C(=O)O)[C@@H](O)[C@@H](N)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H16 compound treatment 0.9148 -0.00352 -0.04 0.8368 0.0276 0.41 0.2642 0.6335 2060325 BPBio1_000522 COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(c34)-c2c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H17 compound treatment 0.8317 -0.0866 -1.02 0.7876 -0.0216 -0.32 -0.9481 -0.8888 3060147 BPBio1_000523 CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H18 compound treatment 0.8835 -0.0348 -0.41 0.8018 -0.00742 -0.11 -0.3678 -0.8685 1076 BPBio1_000524 Cc1cccc(C)c1NC2=NCCCS2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H19 compound treatment 0.877 -0.0413 -0.48 0.7841 -0.0251 -0.38 -0.6094 -0.9924 3068724 BPBio1_000525 C[C@@H](O)[C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCNC=N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H20 compound treatment 0.8596 -0.0587 -0.69 0.7903 -0.0189 -0.28 -0.6881 -0.9235 3179848 BPBio1_000526 C/C=C\1/CC(=C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H21 compound treatment 1.3076 0.389 4.57 0.7906 -0.0186 -0.28 3.0332 0.6627 1448 BPBio1_000527 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H22 compound treatment 0.8462 -0.0722 -0.85 0.8029 -0.0063 -0.09 -0.6658 -0.7814 1001889 BPBio1_000528 COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c2c34)cc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H23 mock treatment 0.8669 -0.0514 -0.6 0.7834 -0.0258 -0.39 -0.7012 -0.9771 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 H24 mock treatment 0.9135 -0.00484 -0.06 0.787 -0.0222 -0.33 -0.2761 -0.8158 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I01 compound treatment 1.1351 0.217 2.54 1.0047 0.195 2.94 3.8778 0.9974 3614608 BPBio1_000529 COc1cc(N)c(Cl)cc1C(=O)OCCCN2CCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I02 compound treatment 1.1087 0.19 2.23 1.0179 0.209 3.14 3.7994 0.9862 52159 BPBio1_000530 COc1ccc2[nH]cc(CCN)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I03 compound treatment 1.1055 0.187 2.2 0.9899 0.181 2.72 3.4755 0.9944 3189191 BPBio1_000531 CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I04 compound treatment 1.1037 0.185 2.18 0.9994 0.19 2.86 3.5611 0.9909 386 BPBio1_000532 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I05 compound treatment 0.8851 -0.0332 -0.39 0.8304 0.0213 0.32 -0.0494 -0.0981 3068885 BPBio1_000533 C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I06 compound treatment 1.0737 0.155 1.82 0.935 0.126 1.89 2.6275 0.9998 2078 BPBio1_000534 CCCCc1ccc(nc1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I07 compound treatment 1.0052 0.0869 1.02 0.9378 0.129 1.93 2.0883 0.9553 1352 BPBio1_000535 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I08 compound treatment 1.0439 0.126 1.47 0.9399 0.131 1.97 2.4317 0.9899 907497 BPBio1_000536 COc1ccc(cc1)c2ccc(N)[n+](CCCC(=O)O)n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I09 compound treatment 1.0271 0.109 1.28 0.9222 0.113 1.7 2.1045 0.9901 3177235 BPBio1_000537 CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]3[C@H]1Cc4cn(C)c5cccc3c45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I10 compound treatment 1.0073 0.089 1.04 0.9297 0.12 1.81 2.0197 0.9657 3616701 BPBio1_000538 C[C@@H]1C(=O)O[C@H]2CC34[C@H]5C[C@@H](C(C)(C)C)[C@@]46[C@@H](O)C(=O)O[C@H]6O[C@@]3(C(=O)O5)[C@@]12O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I11 compound treatment 1.0008 0.0825 0.97 0.9436 0.134 2.02 2.1138 0.9431 3189192 BPBio1_000539 CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I12 compound treatment 0.9695 0.0512 0.6 0.9303 0.121 1.82 1.713 0.8929 716 BPBio1_000540 CN(C)CCC=C1c2ccccc2C=Cc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I13 compound treatment 0.9496 0.0312 0.37 0.9047 0.0955 1.44 1.2746 0.8601 1000229 BPBio1_000541 Nc1c(Br)cc(Br)cc1CN[C@H]2CC[C@H](O)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I14 compound treatment 0.9495 0.0312 0.37 0.8922 0.083 1.25 1.142 0.8775 1300555 BPBio1_000542 CC(C)(C)NCC(O)COc1cccc2NC(=O)CCc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I15 compound treatment 0.9287 0.0104 0.12 0.9213 0.112 1.69 1.278 0.7562 705 BPBio1_000543 CC(Cc1cccc(c1)C(F)(F)F)NCCOC(=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I16 compound treatment 0.8254 -0.0929 -1.09 0.8065 -0.00264 -0.04 -0.7991 -0.7324 2080102 BPBio1_000544 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I17 compound treatment 0.9129 -0.00542 -0.06 0.8503 0.0411 0.62 0.3923 0.631 1000048 BPBio1_000545 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I18 compound treatment 0.8707 -0.0476 -0.56 0.8287 0.0196 0.29 -0.1868 -0.2959 1190 BPBio1_000546 Nc1c2C(O)CCCc2nc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I19 compound treatment 0.8731 -0.0452 -0.53 0.8246 0.0154 0.23 -0.211 -0.3642 1504 BPBio1_000547 O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I20 compound treatment 0.8511 -0.0672 -0.79 0.7966 -0.0126 -0.19 -0.6916 -0.8528 992 BPBio1_000548 CC[C@H]1[C@@H](Cc2cncn2C)COC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I21 compound treatment 0.8789 -0.0394 -0.46 0.8084 -7.94E-4 -0.01 -0.3357 -0.7251 2873 BPBio1_000549 CCc1oc2ccccc2c1C(=O)c3cc(Br)c(O)c(Br)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I22 compound treatment 0.8368 -0.0816 -0.96 0.8091 -1.04E-4 0.0 -0.6779 -0.7083 1265 BPBio1_000550 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4c(Cl)cccc4Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I23 mock treatment 0.8803 -0.0381 -0.45 0.8005 -0.00868 -0.13 -0.4081 -0.877 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 I24 mock treatment 0.8936 -0.0247 -0.29 0.8076 -0.00155 -0.02 -0.2215 -0.7617 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J01 compound treatment 1.1269 0.209 2.45 0.9632 0.154 2.32 3.3689 0.9996 3177404 BPBio1_000551 CNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J02 compound treatment 1.1185 0.2 2.35 0.9497 0.141 2.11 3.1556 0.9986 3560381 BPBio1_000552 NCCCP(=O)(O)CC1CCCCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J03 compound treatment 1.0979 0.18 2.11 0.9469 0.138 2.07 2.9557 1.0 821975 BPBio1_000553 C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J04 compound treatment 1.1828 0.264 3.1 1.0111 0.202 3.04 4.3417 0.9999 3616753 BPBio1_000554 COc1ccc2C[C@@H]3N(CCc4cc(OC)c(O)cc34)Cc2c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J05 compound treatment 1.0491 0.131 1.54 0.9231 0.114 1.71 2.2969 0.9985 3616742 BPBio1_000555 CCC(C)[C@@H]1N[C@@H]2C=Cc3c(cc(nc3[C@H]2O)C(=O)O[C@H](C)[C@@H]4NC(=O)c5csc(n5)[C@@H](NC(=O)[C@H]6CSC(=N6)/C(=C\C)/NC(=O)[C@@H](NC(=O)c7csc(n7)[C@]8(CCC(=N[C@H]8c9csc4n9)c%10nc(cs%10)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)NC(=O)[C@H](C)NC(=O)C(=C)NC(=O)[C@H](C)NC1=O)[C@@H](C)O)[C@@](C)(O)[C@@H](C)O)[C@H](C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J06 compound treatment 1.0937 0.175 2.06 0.9333 0.124 1.87 2.7752 0.9988 3616754 BPBio1_000556 CC[C@@H]1[C@@H](O)N2[C@@H]3CC45[C@H](O)C3C1C[C@H]2[C@@H]5N(C)c6ccccc64 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J07 compound treatment 1.1011 0.183 2.14 0.9351 0.126 1.89 2.8557 0.9981 3177255 BPBio1_000557 CS(=N)(=O)CC[C@H](N)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J08 compound treatment 1.0719 0.154 1.8 0.916 0.107 1.61 2.4102 0.9983 1539 BPBio1_000558 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J09 compound treatment 1.0718 0.153 1.8 0.9346 0.125 1.89 2.6077 0.9997 737 BPBio1_000559 c1nc(cs1)c2nc3ccccc3[nH]2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J10 compound treatment 1.1331 0.215 2.52 0.8873 0.0782 1.18 2.6136 0.9397 3069522 BPBio1_000560 COc1cc(/C=C/C(=O)N2CCC=CC2=O)cc(OC)c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J11 compound treatment 0.9844 0.0661 0.78 0.92 0.111 1.67 1.7271 0.9394 3189445 BPBio1_000561 CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c4c(O)c(/C=N/N5CCN(C)CC5)c(NC(=O)/C(=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(=O)C)[C@@H]1C)/C)c(O)c4c(O)c3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J12 compound treatment 1.008 0.0897 1.05 0.8911 0.0819 1.23 1.6154 0.9969 3100 BPBio1_000562 COc1c2OCOc2cc3CCN(C)Cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J13 compound treatment 0.9472 0.0288 0.34 0.8651 0.0559 0.84 0.8338 0.9201 803 BPBio1_000563 CCc1cc(ccn1)C(=S)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J14 compound treatment 0.9525 0.0342 0.4 0.8482 0.039 0.59 0.6992 0.9829 1000122 BPBio1_000564 O[C@@H]([C@@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J15 compound treatment 0.9639 0.0456 0.53 0.8637 0.0545 0.82 0.9578 0.9785 900 BPBio1_000565 CN1C(=C(O)c2sccc2S1(=O)=O)C(=O)Nc3ccccn3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J16 compound treatment 0.9567 0.0384 0.45 0.8214 0.0122 0.18 0.448 0.9216 1039 BPBio1_000566 CC[C@]1(CCCN2CCc3c4[C@@H]21)CC(=O)n4c5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J17 compound treatment 0.8787 -0.0396 -0.46 0.7988 -0.0104 -0.16 -0.4393 -0.896 3068731 BPBio1_000567 CC(=O)Oc1cc(ccc1C(=O)O)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J18 compound treatment 0.8521 -0.0662 -0.78 0.7746 -0.0345 -0.52 -0.917 -0.9808 2082296 BPBio1_000568 O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J19 compound treatment 0.855 -0.0633 -0.74 0.7629 -0.0463 -0.7 -1.0183 -0.9995 4379 BPBio1_000569 CN1CCCCC1CCN2c3ccccc3Sc4ccc(cc24)S(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J20 compound treatment 0.8453 -0.073 -0.86 0.7627 -0.0465 -0.7 -1.1005 -0.9949 994 BPBio1_000570 N[C@@H](CCONC(=N)N)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J21 compound treatment 0.8162 -0.102 -1.2 0.7537 -0.0555 -0.83 -1.4375 -0.9843 1470254 BPBio1_000571 Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J22 compound treatment 0.8233 -0.095 -1.12 0.7846 -0.0246 -0.37 -1.05 -0.8936 1530 BPBio1_000572 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J23 mock treatment 0.8666 -0.0517 -0.61 0.796 -0.0132 -0.2 -0.5694 -0.8915 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 J24 mock treatment 0.919 7.0E-4 0.01 0.819 0.00979 0.15 0.1099 0.7454 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K01 compound treatment 1.1953 0.277 3.25 0.9914 0.182 2.74 4.2363 0.9964 3561678 BPBio1_000573 COc1cc(COc2cc(N)c(Cl)cc2C(=O)CCC3CCN(CCNS(=O)(=O)C)CC3)cc(OC)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K02 compound treatment 1.1033 0.185 2.17 0.9872 0.178 2.68 3.4285 0.9946 907505 BPBio1_000574 CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K03 compound treatment 1.1421 0.224 2.63 1.0033 0.194 2.92 3.922 0.9986 771 BPBio1_000575 CN1CCC(=C2c3ccsc3C(=O)Cc4ccccc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K04 compound treatment 1.1094 0.191 2.24 0.9733 0.164 2.47 3.3306 0.9989 1055159 BPBio1_000576 NC(CC(=O)c1cccc(O)c1N)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K05 compound treatment 1.1127 0.194 2.28 0.9555 0.146 2.2 3.1693 0.9998 907283 BPBio1_000577 NC(=N)N1CCc2ccccc2C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K06 compound treatment 1.1384 0.22 2.58 0.972 0.163 2.45 3.5583 0.9996 3189433 BPBio1_000578 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K07 compound treatment 1.0231 0.105 1.23 0.9794 0.17 2.56 2.68 0.9436 1000064 BPBio1_000579 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K08 compound treatment 1.12 0.202 2.37 0.9403 0.131 1.97 3.0683 0.9959 3616708 BPBio1_000580 COC1=C[C@H]2[C@H](C3=C2c4c(OC)c(OC)c(OC)cc4CC[C@@H]3NC(=O)C)C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K09 compound treatment 1.0875 0.169 1.99 0.9495 0.14 2.11 2.8959 0.9995 991 BPBio1_000581 CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K10 compound treatment 1.0227 0.104 1.23 0.9485 0.139 2.1 2.3484 0.9674 1134 BPBio1_000582 CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K11 compound treatment 1.0403 0.122 1.43 0.9513 0.142 2.14 2.5245 0.981 1496 BPBio1_000583 CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K12 compound treatment 0.9933 0.075 0.88 0.9407 0.132 1.98 2.0212 0.9335 3174101 BPBio1_000584 CN1CCc2c(C1)c3ccccc3n2Cc4ccccc4.OS(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K13 compound treatment 0.9953 0.077 0.9 0.9753 0.166 2.5 2.4053 0.9055 3068886 BPBio1_000585 CC(C)/N=c/1\cc2n(c3ccc(Cl)cc3)c4ccccc4nc2cc1Nc5ccc(Cl)cc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K14 compound treatment 0.9722 0.0539 0.63 0.8975 0.0883 1.33 1.3867 0.9425 3616712 BPBio1_000586 CN(C)[C@H]1[C@@H]2[C@@H](O)C3C(=C)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N.OC(=O)c1cc(ccc1O)S(=O)(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K15 compound treatment 0.931 0.0127 0.15 0.8651 0.056 0.84 0.7006 0.8196 975 BPBio1_000587 CCN(CC)CCOC(=O)C(CC1CCCO1)Cc2cccc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K16 compound treatment 0.9472 0.0289 0.34 0.8717 0.0626 0.94 0.9048 0.9048 1035 BPBio1_000588 Cc1cccc(CN2CCN(CC2)C(c3ccccc3)c4ccc(Cl)cc4)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K17 compound treatment 0.9036 -0.0147 -0.17 0.8271 0.0179 0.27 0.0685 0.2144 1000105 BPBio1_000589 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K18 compound treatment 0.8297 -0.0886 -1.04 0.8157 0.00652 0.1 -0.6658 -0.6376 988 BPBio1_000590 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K19 compound treatment 0.868 -0.0503 -0.59 0.8053 -0.00385 -0.06 -0.4585 -0.7726 341 BPBio1_000591 N[C@@H](Cn1ccc(=O)c(O)c1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K20 compound treatment 1.0012 0.0829 0.97 0.9066 0.0974 1.47 1.7242 0.9803 449 BPBio1_000592 CC1=CC(=O)c2ccccc2C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K21 compound treatment 0.8329 -0.0854 -1.0 0.7582 -0.051 -0.77 -1.2512 -0.9912 2777 BPBio1_000593 COc1cc(N)c(Cl)cc1C(=O)NC2CCN(Cc3ccccc3)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K22 compound treatment 0.8199 -0.0984 -1.16 0.7728 -0.0364 -0.55 -1.2033 -0.9416 3069122 BPBio1_000594 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O.COC(N)(CO)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K23 mock treatment 0.8705 -0.0478 -0.56 0.8143 0.00511 0.08 -0.3427 -0.6047 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 K24 mock treatment 0.9124 -0.00591 -0.07 0.8278 0.0186 0.28 0.1486 0.516 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L01 compound treatment 1.1556 0.237 2.78 1.0087 0.199 3.0 4.0903 0.9993 907368 BPBio1_000595 CC(C)n1cc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)OC(C)C(C)O)c4cccc1c24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L02 compound treatment 1.1267 0.208 2.45 0.9734 0.164 2.47 3.4757 1.0 3614707 BPBio1_000596 CCOC(OCC)P(=O)(O)CCCNCc1ccc(Cl)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L03 compound treatment 1.136 0.218 2.55 0.9706 0.161 2.43 3.5224 0.9997 907463 BPBio1_000597 Cc1nc2ccccn2c(=O)c1CCN3CCC(CC3)C(=O)c4ccc(F)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L04 compound treatment 1.1276 0.209 2.46 0.9231 0.114 1.71 2.9484 0.9845 1578 BPBio1_000598 CC1=NCCc2c1[nH]c3cc(O)ccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L05 compound treatment 1.12 0.202 2.37 0.9618 0.153 2.29 3.2963 0.9999 1024517 BPBio1_000599 COc1cc2CCNC(C)c2cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L06 compound treatment 1.0811 0.163 1.91 0.9177 0.109 1.63 2.5056 0.9969 1043296 BPBio1_000600 Cc1nccc2c3ccc(O)cc3[nH]c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L07 compound treatment 1.0964 0.178 2.09 0.9299 0.121 1.82 2.7615 0.9975 1193 BPBio1_000601 CCOc1ccc(NC(=O)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L08 compound treatment 1.0806 0.162 1.9 0.9418 0.133 2.0 2.7573 0.9997 297849 BPBio1_000602 COc1ccc2c(c1)[nH]c3c(C)nccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L09 compound treatment 1.055 0.137 1.6 0.9219 0.113 1.7 2.3332 0.9996 3474094 BPBio1_000603 OC1=C(C2CCC(CC2)c3ccc(Cl)cc3)C(=O)c4ccccc4C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L10 compound treatment 0.9769 0.0586 0.69 0.9422 0.133 2.0 1.9003 0.8985 2057 BPBio1_000604 Cc1c2[nH]c3ccccc3c2c(C)c4cnccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L11 compound treatment 1.0219 0.104 1.22 0.9466 0.137 2.07 2.3216 0.968 3058468 BPBio1_000605 COc1ccc(OC)c(c1)C(O)C(C)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L12 compound treatment 0.8433 -0.075 -0.88 0.8498 0.0407 0.61 -0.1903 -0.1775 3069524 BPBio1_000606 O=C1C=CC(=O)c2c1ccc3c2ccc4ccccc43 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L13 compound treatment 0.9665 0.0482 0.57 0.9361 0.127 1.91 1.7502 0.879 1001857 BPBio1_000607 CC(C)NC[C@@H](O)COc1ccc(CC(=O)N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L14 compound treatment 0.9289 0.0105 0.12 0.8671 0.0579 0.87 0.7032 0.7996 3616759 BPBio1_000608 CN(CCCCCCCCCCN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C)C(=O)Oc2cccc(c2)[N+](C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L15 compound treatment 0.9413 0.023 0.27 0.8453 0.0361 0.54 0.5749 0.9478 904 BPBio1_000609 NC(=O)CN1CCCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L16 compound treatment 0.9096 -0.00867 -0.1 0.8247 0.0155 0.23 0.0927 0.3647 1494 BPBio1_000610 C1CN(CCN1)c2ccc3ccccc3n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L17 compound treatment 0.9048 -0.0135 -0.16 0.8061 -0.00304 -0.05 -0.1445 -0.8752 948 BPBio1_000611 O=C1C(C(=O)c2ccccc12)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L18 compound treatment 0.8922 -0.0261 -0.31 0.7728 -0.0364 -0.55 -0.6035 -0.9627 3616761 BPBio1_000612 C1CCN2C[C@@H]3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L19 compound treatment 0.8702 -0.0481 -0.56 0.7534 -0.0558 -0.84 -0.9927 -0.9814 3189446 BPBio1_000613 COc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc3CCC(NC(=O)C)c4cc(=O)c(SC)ccc4-c3c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L20 compound treatment 0.7769 -0.141 -1.66 0.7668 -0.0424 -0.64 -1.6246 -0.9137 3043 BPBio1_000614 C[C@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)C)C(=O)COC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L21 compound treatment 0.8271 -0.0912 -1.07 0.7493 -0.0599 -0.9 -1.3944 -0.9963 3068774 BPBio1_000615 Nc1cc(C(=C(Cl)Cl)Cl)c(cc1S(=O)(=O)N)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L22 compound treatment 0.8209 -0.0974 -1.14 0.7726 -0.0365 -0.55 -1.197 -0.9437 1035065 BPBio1_000616 Cc1nccc2c3ccccc3[nH]c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L23 mock treatment 0.8596 -0.0587 -0.69 0.7998 -0.00937 -0.14 -0.5871 -0.8343 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 L24 mock treatment 0.9319 0.0136 0.16 0.8185 0.00936 0.14 0.2127 0.9979 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M01 compound treatment 1.1529 0.235 2.75 1.0272 0.218 3.28 4.2656 0.9962 3060500 BPBio1_000617 O=C(OCCN1CCCCC1)c2c[nH]c3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M02 compound treatment 1.1014 0.183 2.15 1.0205 0.211 3.18 3.7665 0.9818 1761 BPBio1_000618 CN1C2CCC1CC(C2)OC(=O)c3c[nH]c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M03 compound treatment 1.1134 0.195 2.29 0.9791 0.17 2.56 3.4257 0.9985 907366 BPBio1_000619 Cc1cccc(C)c1NC(=O)CN2CCN(CCCC(c3ccc(F)cc3)c4ccc(F)cc4)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M04 compound treatment 1.0936 0.175 2.06 0.9709 0.162 2.43 3.1743 0.9965 2830 BPBio1_000620 Clc1ccc2n(C3CCN(CCCn4c(=O)[nH]c5ccccc45)CC3)c(=O)[nH]c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M05 compound treatment 1.1093 0.191 2.24 0.9601 0.151 2.27 3.1896 1.0 3480396 BPBio1_000621 CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M06 compound treatment 1.132 0.214 2.51 0.9601 0.151 2.27 3.3775 0.9988 3616717 BPBio1_000622 Nc1nc(cs1)/C(=N/OCC(=O)O)/C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M07 compound treatment 1.1209 0.203 2.38 0.9855 0.176 2.65 3.5567 0.9985 86 BPBio1_000623 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M08 compound treatment 1.1434 0.225 2.64 0.9299 0.121 1.82 3.1519 0.9833 3616719 BPBio1_000624 CN(C(=O)C)c1c(I)c(NC(=O)C)c(I)c(C(=O)N[C@H]2C(O)O[C@H](CO)[C@@H](O)[C@@H]2O)c1I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M09 compound treatment 1.0813 0.163 1.91 0.9411 0.132 1.98 2.7558 0.9998 1210 BPBio1_000625 CC(C)(C)c1cc(SC(C)(C)Sc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M10 compound treatment 1.0812 0.163 1.91 0.9415 0.132 1.99 2.7589 0.9998 3616721 BPBio1_000626 C[C@@H](O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O)[C@@H]1NC(=O)C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M11 compound treatment 0.9842 0.0659 0.77 0.9286 0.119 1.8 1.8168 0.9292 1135 BPBio1_000627 OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M12 compound treatment 1.0006 0.0823 0.97 0.9344 0.125 1.88 2.0144 0.9519 2181 BPBio1_000628 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3cc(O)c(O)c(O)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M13 compound treatment 0.9557 0.0374 0.44 0.912 0.103 1.55 1.4039 0.8734 907273 BPBio1_000629 Fc1ccc(cc1)C(OCCN2CCN(CCCc3ccccc3)CC2)c4ccc(F)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M14 compound treatment 0.9608 0.0425 0.5 0.9069 0.0977 1.47 1.3922 0.8969 1733214 BPBio1_000630 Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)cc3O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M15 compound treatment 0.9258 0.00748 0.09 0.888 0.0788 1.19 0.9001 0.7574 990 BPBio1_000631 CCN(CC)CCOCCOC(=O)C1(CCCC1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M16 compound treatment 0.9311 0.0128 0.15 0.8856 0.0764 1.15 0.9186 0.7926 895 BPBio1_000632 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M17 compound treatment 0.9944 0.0761 0.89 0.7559 -0.0533 -0.8 0.0647 0.0539 1351 BPBio1_000633 Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]3c(C)cc(N)c4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M18 compound treatment 0.8695 -0.0488 -0.57 0.8172 0.00807 0.12 -0.3193 -0.5453 822 BPBio1_000634 CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M19 compound treatment 0.851 -0.0673 -0.79 0.7589 -0.0503 -0.76 -1.0931 -0.9998 3060108 BPBio1_000635 CC(=O)N1CCN(CC1)c2ccc(OC[C@H]3CO[C@@](Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M20 compound treatment 0.8485 -0.0698 -0.82 0.7742 -0.035 -0.53 -0.9512 -0.977 1067495 BPBio1_000636 [O-][N+](=O)c1cnc(s1)N2CCNC2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M21 compound treatment 0.8446 -0.0737 -0.87 0.7892 -0.02 -0.3 -0.8245 -0.9002 3616670 BPBio1_000637 C[C@@H]1[C@H](O)CC[C@@]2(C)C1CC[C@@]3(C)[C@H]2[C@H](O)C[C@H]4/C(=C(\CCC=C(C)C)/C(=O)O)/[C@H](C[C@@]43C)OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M22 compound treatment 0.8244 -0.0939 -1.1 0.8029 -0.00629 -0.09 -0.8463 -0.765 3069161 BPBio1_000638 NCc1ccccc1CC(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4CC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M23 mock treatment 0.8789 -0.0394 -0.46 0.8305 0.0213 0.32 -0.1001 -0.1781 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 M24 mock treatment 0.9221 0.00374 0.04 0.8096 4.45E-4 0.01 0.0358 0.8056 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N01 compound treatment 1.1486 0.23 2.7 0.9929 0.184 2.76 3.865 0.9999 2079 BPBio1_000639 NC1CC(=CC=C1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N02 compound treatment 1.1432 0.225 2.64 1.0058 0.197 2.96 3.9569 0.9984 3614708 BPBio1_000640 C[C@H](NC[C@H](O)CP(=O)(O)CC1CCCCC1)c2ccc(Cl)c(Cl)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N03 compound treatment 1.118 0.2 2.34 1.0234 0.214 3.22 3.9358 0.9878 1309 BPBio1_000641 Cc1cc(C2CCCCC2)n(O)c(=O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N04 compound treatment 1.1194 0.201 2.36 0.9457 0.136 2.05 3.1201 0.9976 1048750 BPBio1_000642 COc1ccc2[nH]c3C(=NCCc3c2c1)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N05 compound treatment 1.1938 0.275 3.23 0.9246 0.115 1.74 3.5132 0.9574 722 BPBio1_000643 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N06 compound treatment 1.1159 0.198 2.32 0.9724 0.163 2.45 3.3747 0.9996 3069526 BPBio1_000644 C[N+]1(C)CCC[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N07 compound treatment 1.1115 0.193 2.27 0.9859 0.177 2.66 3.4823 0.9969 1213 BPBio1_000645 CNCCc1ccccn1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N08 compound treatment 1.1624 0.244 2.86 0.9438 0.135 2.02 3.4564 0.9855 2709 BPBio1_000646 Cc1ncc(CO)c(CO)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N09 compound treatment 1.1285 0.21 2.47 0.9477 0.139 2.08 3.218 0.9965 3177389 BPBio1_000647 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N10 compound treatment 1.1056 0.187 2.2 0.921 0.112 1.68 2.7432 0.9913 3560436 BPBio1_000648 O=c1cccc2[C@H]3CNC[C@H](C3)Cn21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N11 compound treatment 1.0307 0.112 1.32 0.9727 0.164 2.46 2.6716 0.9574 1000096 BPBio1_000649 C1CN2CC(N=C2S1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N12 compound treatment 1.0063 0.088 1.03 0.9729 0.164 2.46 2.4706 0.9256 1039072 BPBio1_000650 CN1C2CCCC1CC(=O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N13 compound treatment 1.0263 0.108 1.27 0.9586 0.149 2.25 2.4853 0.9633 3068775 BPBio1_000651 CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N14 compound treatment 0.9549 0.0366 0.43 0.8881 0.0789 1.19 1.1425 0.9056 3189579 BPBio1_000652 CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N15 compound treatment 0.9391 0.0208 0.24 0.8347 0.0255 0.38 0.4441 0.9761 3616743 BPBio1_000653 CCOC(=O)/N=c\1/c[n+]([n-]o1)N2CCOCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N16 compound treatment 0.9573 0.0389 0.46 0.8408 0.0317 0.48 0.6598 0.9998 1117 BPBio1_000654 Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cnc2[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N17 compound treatment 0.8931 -0.0252 -0.3 0.7654 -0.0438 -0.66 -0.6745 -0.9346 1000114 BPBio1_000655 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N18 compound treatment 0.8982 -0.0202 -0.24 0.7899 -0.0192 -0.29 -0.372 -0.995 3189580 BPBio1_000656 C[C@@H]1NCCc2cc(O)c(O)cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N19 compound treatment 0.8756 -0.0427 -0.5 0.7468 -0.0623 -0.94 -1.0171 -0.9569 1365793 BPBio1_000657 COc1ccc(CN2CCNCC2)c(OC)c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N20 compound treatment 0.8577 -0.0606 -0.71 0.7484 -0.0608 -0.91 -1.1492 -0.9923 1014994 BPBio1_000658 CN(C)Cc1c[nH]c2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N21 compound treatment 1.1998 0.281 3.3 0.8251 0.0159 0.24 2.5051 0.7564 3103826 BPBio1_000659 C/C/1=C\CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N22 compound treatment 0.8792 -0.0391 -0.46 0.8036 -0.0056 -0.08 -0.3843 -0.823 3189581 BPBio1_000660 CCCCc1cc2ccccc2c(OCCN(C)C)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N23 mock treatment 0.9115 -0.00682 -0.08 0.8069 -0.00228 -0.03 -0.0809 -0.9286 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 N24 mock treatment 0.9197 0.00143 0.02 0.8273 0.0181 0.27 0.2042 0.7492 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O01 compound treatment 1.1233 0.205 2.41 1.0366 0.227 3.42 4.1195 0.9852 1393 BPBio1_000661 CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O02 compound treatment 1.1128 0.194 2.28 0.9997 0.191 2.87 3.6396 0.9936 3177047 BPBio1_000662 CCCN(CCC)CCc1c[nH]c2ccc(cc12)C(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O03 compound treatment 1.1467 0.228 2.68 0.9863 0.177 2.66 3.7791 1.0 743 BPBio1_000663 CC(C)(C)NCC(O)c1cc(O)cc(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O04 compound treatment 1.0698 0.151 1.78 0.9176 0.108 1.63 2.4104 0.9991 1000325 BPBio1_000664 C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O05 compound treatment 1.1002 0.182 2.13 0.9621 0.153 2.3 3.1349 0.9993 3616672 BPBio1_000665 O[C@H]([C@@H](O)C(=O)O)C(=O)O.Fc1ccc(cc1)C(=O)C2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O06 compound treatment 1.1799 0.262 3.07 0.9497 0.141 2.11 3.6648 0.9834 3616726 BPBio1_000666 CC(C)(CO)C(O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)C(O)C(C)(C)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O07 compound treatment 1.1392 0.221 2.59 0.9674 0.158 2.38 3.5153 0.9991 907335 BPBio1_000667 C[N+]1(C)CCOC(O)(C1)c2ccc(cc2)c3ccc(cc3)C4(O)C[N+](C)(C)CCO4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O08 compound treatment 1.186 0.268 3.14 0.9733 0.164 2.47 3.9663 0.9929 3189436 BPBio1_000668 CO[C@]1(NC(=O)C2SC(=C(C(=O)N)C(=O)O)S2)[C@H]3SCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O09 compound treatment 1.1574 0.239 2.81 0.9512 0.142 2.14 3.4942 0.9909 698 BPBio1_000669 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O10 compound treatment 1.0904 0.172 2.02 0.9877 0.178 2.68 3.3258 0.9902 1534 BPBio1_000670 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O11 compound treatment 1.0661 0.148 1.73 0.9981 0.189 2.84 3.2355 0.972 3616675 BPBio1_000671 NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O12 compound treatment 1.0484 0.13 1.53 1.0139 0.205 3.08 3.2567 0.9477 1537011 BPBio1_000672 CN(C)CCC(c1ccc(Br)cc1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O13 compound treatment 0.9983 0.08 0.94 0.9692 0.16 2.41 2.3659 0.9157 3616678 BPBio1_000673 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O14 compound treatment 1.0846 0.166 1.95 0.9771 0.168 2.53 3.1654 0.9919 2551 BPBio1_000674 COc1cc(NC(C)CCCN)c2ncccc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O15 compound treatment 1.0364 0.118 1.39 0.9553 0.146 2.2 2.5337 0.9753 3068926 BPBio1_000675 CCN(CC)CCOc1ccc(cc1)/C(=C(/Cl)\c2ccccc2)/c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O16 compound treatment 0.9519 0.0336 0.39 0.8984 0.0892 1.34 1.2279 0.8778 1072 BPBio1_000676 CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O17 compound treatment 0.9425 0.0242 0.28 0.8677 0.0585 0.88 0.8227 0.8901 3616680 BPBio1_000677 CN1CCCN=C1/C=C/c2cccc(O)c2.OC(=O)c1c(O)cc2ccccc2c1Cc3c(C(=O)O)c(O)cc4ccccc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O18 compound treatment 0.8491 -0.0692 -0.81 0.8524 0.0432 0.65 -0.1152 -0.1107 3480329 BPBio1_000678 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(Cl)c2Cl)C(=O)OC)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O19 compound treatment 0.8723 -0.046 -0.54 0.8159 0.00675 0.1 -0.3104 -0.5645 1041 BPBio1_000679 CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O20 compound treatment 0.8542 -0.0641 -0.75 0.7992 -0.01 -0.15 -0.6385 -0.8321 1362 BPBio1_000680 COc1c2occc2cc3ccc(=O)oc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O21 compound treatment 0.9008 -0.0175 -0.21 0.8168 0.00764 0.11 -0.0641 -0.2721 3075213 BPBio1_000681 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O22 compound treatment 0.9899 0.0716 0.84 0.9513 0.142 2.14 2.1053 0.9167 3616730 BPBio1_000682 COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O23 mock treatment 0.9463 0.028 0.33 0.7959 -0.0133 -0.2 0.0915 0.2379 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 O24 mock treatment 0.9582 0.0399 0.47 0.8316 0.0224 0.34 0.5699 0.987 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P01 compound treatment 1.1076 0.189 2.22 1.0905 0.281 4.23 4.5628 0.9548 3061087 BPBio1_000683 NC/C=C/C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P02 compound treatment 1.1216 0.203 2.39 1.039 0.23 3.46 4.1305 0.9836 3614710 BPBio1_000684 C[C@H](NC[C@H](O)CP(=O)(O)Cc1ccccc1)c2ccc(Cl)c(Cl)c2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P03 compound treatment 1.0883 0.17 2.0 0.9989 0.19 2.85 3.428 0.9847 922 BPBio1_000685 CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P04 compound treatment 1.0997 0.181 2.13 1.0042 0.195 2.93 3.5787 0.9876 3382 BPBio1_000686 Cc1c(CCO)sc[n+]1Cc2cnc(C)nc2N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P05 compound treatment 1.14 0.222 2.6 1.0078 0.199 2.99 3.9518 0.9976 2284 BPBio1_000687 C[C@H](Cc1ccccc1)N(C)CC#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P06 compound treatment 1.2089 0.291 3.41 0.9713 0.162 2.44 4.1358 0.9864 3487152 BPBio1_000688 CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P07 compound treatment 1.1907 0.272 3.2 1.0134 0.204 3.07 4.4328 0.9998 1020 BPBio1_000689 NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(=N)N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P08 compound treatment 1.2182 0.3 3.52 0.9955 0.186 2.8 4.47 0.9936 2041 BPBio1_000690 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P09 compound treatment 1.1901 0.272 3.19 0.9881 0.179 2.69 4.158 0.9964 196 BPBio1_000691 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P10 compound treatment 1.1415 0.223 2.62 0.9853 0.176 2.65 3.7251 1.0 3211 BPBio1_000692 Cc1cc2nc3c(=O)[nH]c(=O)nc3n(C[C@H](O)[C@H](O)[C@H](O)CO)c2cc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P11 compound treatment 1.1289 0.211 2.47 0.9992 0.19 2.86 3.7688 0.9974 1931603 BPBio1_000693 Oc1ccc(cc1)C(=O)N/N=C/c2ccc(o2)[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P12 compound treatment 1.1024 0.184 2.16 1.0108 0.202 3.03 3.6718 0.9862 3189582 BPBio1_000694 CC[C@H]1CN2CCC1C[C@H]2[C@H](O)c3ccnc4ccc(OC)cc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P13 compound treatment 1.1808 0.262 3.08 1.1185 0.309 4.65 5.4678 0.98 804 BPBio1_000695 COc1c(C)c2COC(=O)c2c(O)c1C/C=C(\C)/CCC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P14 compound treatment 1.0963 0.178 2.09 0.9795 0.17 2.56 3.2879 0.9949 824 BPBio1_000696 CC[C@]1(CCCN2CCc3c4[C@@H]21)C[C@@](O)(C(=O)OC)n4c5ccccc35 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P15 compound treatment 1.0773 0.159 1.87 0.9494 0.14 2.11 2.8103 0.9982 1001314 BPBio1_000697 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)[C@@H]4N[C@@H](COCCOC)O[C@H]([C@H]4C)[C@]1(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P16 compound treatment 1.045 0.127 1.49 0.8996 0.0904 1.36 2.0132 0.999 3069528 BPBio1_000698 C/C=C\1/C[C@@H](C)[C@](O)(CO)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P17 compound treatment 1.0299 0.112 1.31 0.8855 0.0763 1.15 1.7377 0.9978 3474312 BPBio1_000699 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P18 compound treatment 1.009 0.0907 1.06 0.8914 0.0822 1.24 1.6271 0.9972 3187609 BPBio1_000700 C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23CN1C)N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P19 compound treatment 0.9838 0.0654 0.77 0.8502 0.041 0.62 0.9791 0.9941 3060137 BPBio1_000701 COc1ccccc1N2CCN(CCCCNC(=O)c3ccc4ccccc4c3)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P20 compound treatment 0.941 0.0227 0.27 0.8686 0.0594 0.89 0.8203 0.8797 3616767 BPBio1_000702 CC[C@@H](C)C(=O)O[C@H]1[C@H](O)[C@H]2[C@@H](CN3C[C@@H](C)CC[C@H]3[C@@]2(C)O)C4C[C@]5(O[C@]6(O)[C@H]7[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]5[C@@]41O)[C@@]7(C)CC[C@@H]6OC(=O)[C@](C)(O)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P21 compound treatment 0.9928 0.0745 0.87 0.8399 0.0307 0.46 0.9451 0.9557 3616746 BPBio1_000703 CC(O)C(=O)C.CC(Cc1ccccc1)NCCC(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P22 compound treatment 0.9573 0.039 0.46 0.8367 0.0275 0.41 0.6161 0.9987 3616768 BPBio1_000704 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)N9C[C@@H](C)CC[C@H]19 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P23 mock treatment 0.9425 0.0242 0.28 0.8567 0.0475 0.71 0.7059 0.918 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2321 P24 mock treatment 0.9389 0.0205 0.24 0.8692 0.06 0.9 0.8087 0.8656 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A01 compound treatment 0.9768 0.109 1.27 0.9643 0.0924 1.39 1.8839 0.9991 3614712 BPBio1_000705 NCC(CS(=O)(=O)O)c1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A02 compound treatment 0.9283 0.06 0.7 0.919 0.0471 0.71 0.9993 1.0 3198426 BPBio1_000706 NCC(CC(=O)O)c1ccc(Cl)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A03 compound treatment 0.9243 0.056 0.66 0.9217 0.0498 0.75 0.9946 0.9979 3187611 BPBio1_000707 COc1cc(ccc1c2nc3ncccc3[nH]2)S(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A04 compound treatment 0.8986 0.0304 0.36 0.8971 0.0252 0.38 0.5198 0.9995 1606 BPBio1_000708 NS(=O)(=O)c1cc2c(NC(CSCC=C)NS2(=O)=O)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A05 compound treatment 0.8926 0.0243 0.29 0.9043 0.0324 0.49 0.5466 0.9675 1254 BPBio1_000709 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A06 compound treatment 0.8779 0.00965 0.11 0.9176 0.0458 0.69 0.5667 0.8125 1524 BPBio1_000710 CC(C)Nc1c(C)n(C)n(c2ccccc2)c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A07 compound treatment 0.7769 -0.0914 -1.07 0.8442 -0.0277 -0.42 -1.0527 -0.9149 3187612 BPBio1_000711 CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A08 compound treatment 0.8839 0.0156 0.18 0.874 0.00213 0.03 0.1519 0.8185 883 BPBio1_000712 CC(Oc1ccccc1)C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A09 compound treatment 0.8576 -0.0107 -0.13 0.8976 0.0257 0.39 0.185 0.4544 3069530 BPBio1_000713 CC(=O)NC1CCSC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A10 compound treatment 0.8736 0.00537 0.06 0.855 -0.0168 -0.25 -0.1345 -0.5154 887 BPBio1_000714 COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A11 compound treatment 0.8007 -0.0676 -0.79 0.821 -0.0509 -0.77 -1.1025 -0.9998 1000240 BPBio1_000715 CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A12 compound treatment 1.1124 0.244 2.87 1.0791 0.207 3.12 4.2299 0.9991 745 BPBio1_000716 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A13 compound treatment 0.9327 0.0644 0.76 0.9745 0.103 1.54 1.6256 0.9461 3616769 BPBio1_000717 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)OC2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A14 compound treatment 0.8758 0.00755 0.09 0.895 0.0231 0.35 0.3087 0.8596 3263 BPBio1_000718 CNC(C)(C)Cc1ccccc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A15 compound treatment 0.875 0.00674 0.08 0.8914 0.0196 0.29 0.264 0.8664 2060360 BPBio1_000719 C1CN=C(C1)c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A16 compound treatment 0.8644 -0.00389 -0.05 0.9022 0.0303 0.46 0.2903 0.6331 3187750 BPBio1_000720 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A17 compound treatment 0.8498 -0.0185 -0.22 0.8838 0.0119 0.18 -0.0266 -0.0947 3069532 BPBio1_000721 C[N+]1(C)C[C@@H](O)C[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A18 compound treatment 0.8624 -0.00587 -0.07 0.8934 0.0215 0.32 0.18 0.5443 751 BPBio1_000722 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A19 compound treatment 0.855 -0.0133 -0.16 0.8743 0.00246 0.04 -0.084 -0.5246 946 BPBio1_000723 OCCNC(=O)Cn1ccnc1[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A20 compound treatment 0.8425 -0.0258 -0.3 0.9159 0.0441 0.66 0.2545 0.3492 1146 BPBio1_000724 Nc1ccc(cc1)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A21 compound treatment 0.8539 -0.0143 -0.17 0.9116 0.0397 0.6 0.3036 0.489 3616770 BPBio1_000725 NCCC(O)C(=O)N[C@@H]1C[C@H](N)[C@@H](OC2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2N)[C@H](OC3O[C@H](CO)C(O)[C@H]3O)[C@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A22 compound treatment 0.8965 0.0283 0.33 0.9115 0.0397 0.6 0.6565 0.9616 3616809 BPBio1_000726 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC(=O)[C@]23C)O[C@@]61CC[C@@H](C)CO6 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A23 mock treatment 0.8839 0.0156 0.18 0.9386 0.0667 1.0 0.8389 0.8224 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 A24 mock treatment 0.8751 0.00687 0.08 0.9079 0.036 0.54 0.4402 0.8034 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B01 compound treatment 0.9685 0.1 1.18 0.9469 0.0751 1.13 1.6304 0.9998 3614714 BPBio1_000727 NC(=N)S/C=C\C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B02 compound treatment 0.913 0.0448 0.53 0.9293 0.0575 0.86 0.9826 0.9715 3614718 BPBio1_000728 CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B03 compound treatment 0.9004 0.0321 0.38 0.9085 0.0367 0.55 0.6561 0.9827 1412 BPBio1_000729 CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B04 compound treatment 0.8885 0.0202 0.24 0.8859 0.014 0.21 0.3166 0.9983 1300 BPBio1_000730 OC(=O)c1cccnc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B05 compound treatment 0.8858 0.0175 0.21 0.893 0.0212 0.32 0.3704 0.9776 3069629 BPBio1_000731 CC(=O)/N=c/1\sc(nn1C)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B06 compound treatment 0.883 0.0148 0.17 0.8982 0.0263 0.4 0.4027 0.9312 2819 BPBio1_000732 CCC1(C)CC(=O)NC(=O)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B07 compound treatment 0.8676 -6.61E-4 -0.01 0.8793 0.0074 0.11 0.0732 0.6562 818 BPBio1_000733 CCC1(CC)C(=O)NC=CC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B08 compound treatment 0.8978 0.0296 0.35 1.0322 0.16 2.41 1.9504 0.8006 3187897 BPBio1_000734 C[C@]12[C@H](CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3C[C@H]1O)C5=CC(=O)OC5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B09 compound treatment 0.8563 -0.012 -0.14 0.8743 0.00248 0.04 -0.073 -0.5022 795 BPBio1_000735 CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B10 compound treatment 0.8405 -0.0277 -0.33 0.8822 0.0104 0.16 -0.1197 -0.3316 4370 BPBio1_000736 CNCC(O)C(O)C(O)C(O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B11 compound treatment 0.859 -0.00929 -0.11 0.8653 -0.00661 -0.1 -0.1474 -0.9989 1129 BPBio1_000737 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B12 compound treatment 0.9209 0.0526 0.62 0.9941 0.122 1.84 1.7362 0.8955 2117591 BPBio1_000738 C[C@]12[C@H]3CC[C@H](O3)[C@]2(C)C(=O)OC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B13 compound treatment 0.8802 0.0119 0.14 0.8786 0.00674 0.1 0.1706 0.9874 755 BPBio1_000739 CC(CN(C)C)CN1c2ccccc2CCc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B14 compound treatment 0.8939 0.0256 0.3 0.9165 0.0446 0.67 0.687 0.9346 1999 BPBio1_000740 Oc1c(I)cc(Cl)c2cccnc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B15 compound treatment 0.928 0.0597 0.7 0.8895 0.0176 0.26 0.6829 0.9114 1088922 BPBio1_000741 CN(C)CCN(Cc1ccc(Cl)cc1)c2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B16 compound treatment 0.8338 -0.0345 -0.4 0.8823 0.0105 0.16 -0.175 -0.403 838 BPBio1_000742 COc1ccc(C(=O)c2ccccc2)c(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B17 compound treatment 0.8188 -0.0495 -0.58 0.8371 -0.0348 -0.52 -0.7806 -0.9986 3043753 BPBio1_000743 [O-][N+](=O)c1ccc(/C=N/N2CCOC2=O)o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B18 compound treatment 0.849 -0.0193 -0.23 0.8565 -0.0154 -0.23 -0.3239 -0.9999 681 BPBio1_000744 CC(CN1c2ccccc2Sc3ccccc13)N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B19 compound treatment 0.8578 -0.0105 -0.12 0.8674 -0.00447 -0.07 -0.1347 -0.9593 2570 BPBio1_000745 NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B20 compound treatment 0.8515 -0.0168 -0.2 0.8667 -0.00514 -0.08 -0.1942 -0.9164 1225 BPBio1_000746 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B21 compound treatment 0.8697 0.00145 0.02 0.9253 0.0535 0.8 0.5805 0.7219 871 BPBio1_000747 Clc1ccc(CSC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B22 compound treatment 0.8296 -0.0387 -0.45 0.8598 -0.012 -0.18 -0.4492 -0.9188 3487233 BPBio1_000748 CC(O)Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B23 mock treatment 0.8473 -0.0209 -0.25 0.8508 -0.021 -0.32 -0.3976 -0.9922 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 B24 mock treatment 0.871 0.00271 0.03 0.8687 -0.00318 -0.05 -0.0114 -0.1984 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C01 compound treatment 0.9381 0.0698 0.82 0.9419 0.07 1.05 1.3242 0.9923 2069299 BPBio1_000749 CC1(C)CO[C@@H](CC(=O)O)CN1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C02 compound treatment 0.9286 0.0603 0.71 0.9421 0.0703 1.06 1.2477 0.9811 678 BPBio1_000750 NCC(CC(=O)O)c1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C03 compound treatment 0.9103 0.0421 0.49 0.9015 0.0297 0.45 0.6646 0.9987 1624 BPBio1_000751 CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C04 compound treatment 0.8869 0.0186 0.22 0.873 0.00114 0.02 0.1668 0.7602 706 BPBio1_000752 Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C05 compound treatment 0.8519 -0.0164 -0.19 0.8766 0.00474 0.07 -0.0854 -0.4168 3616771 BPBio1_000753 CC(=C)[C@H]1[C@H]2OC(=O)C1[C@]3(O)CC4O[C@]45C(=O)O[C@H]2[C@@]53C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C06 compound treatment 0.8874 0.0191 0.22 0.909 0.0372 0.56 0.5538 0.9197 1149 BPBio1_000754 CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C07 compound treatment 0.8377 -0.0306 -0.36 0.9066 0.0348 0.52 0.116 0.183 1244 BPBio1_000755 C[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C08 compound treatment 0.8427 -0.0256 -0.3 0.867 -0.00484 -0.07 -0.2638 -0.8537 3616810 BPBio1_000756 COCCc1ccc(OCC(O)CNC(C)C)cc1.O[C@H]([C@@H](O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C09 compound treatment 0.8354 -0.0329 -0.39 0.855 -0.0168 -0.25 -0.4522 -0.979 3187616 BPBio1_000757 C/C(=C(\CCOP(=O)(O)O)/SC(=O)c1ccccc1)/N(Cc2cnc(C)nc2N)C=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C10 compound treatment 0.8484 -0.0199 -0.23 0.8403 -0.0315 -0.47 -0.5006 -0.9467 3187752 BPBio1_000758 C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C11 compound treatment 0.8194 -0.0489 -0.57 0.8188 -0.053 -0.8 -0.9694 -0.987 3069534 BPBio1_000759 CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CCl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C12 compound treatment 0.8832 0.0149 0.18 0.8589 -0.013 -0.2 -0.0141 -0.0539 359 BPBio1_000760 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C13 compound treatment 0.9737 0.105 1.24 1.007 0.135 2.03 2.312 0.9717 3616772 BPBio1_000761 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](OC(=O)C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](C)O3)[C@@H](C)O2)O[C@H]5CC[C@@]6(C)[C@H](CC[C@@]7(C)[C@@]8(O)CC[C@H](C9=CC(=O)OC9)[C@@]8(C)[C@H](O)C[C@]67C)C5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C14 compound treatment 0.8882 0.0199 0.23 0.8763 0.00446 0.07 0.2125 0.8749 689 BPBio1_000762 Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C(=O)O)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C15 compound treatment 0.854 -0.0143 -0.17 0.8582 -0.0136 -0.21 -0.2636 -0.995 3103678 BPBio1_000763 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C16 compound treatment 0.84 -0.0283 -0.33 0.8829 0.0111 0.17 -0.1167 -0.3143 3616811 BPBio1_000764 CC(C)CC(=O)O[C@H]1[C@@H](O[C@@H]2C[C@H]([C@H]3CC[C@]4(C[C@H]5CC[C@H]4[C@]3(C)C2)[C@@H](O)C5=C)C(=O)O)O[C@H](CO)[C@@H](OS(=O)(=O)O)[C@@H]1OS(=O)(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C17 compound treatment 0.8543 -0.0139 -0.16 0.8751 0.0032 0.05 -0.0816 -0.4789 827 BPBio1_000765 CCCCC1(COC(=O)CCC(=O)O)C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C18 compound treatment 0.8395 -0.0288 -0.34 0.8457 -0.0262 -0.39 -0.5178 -0.9971 873 BPBio1_000766 Nc1nc(=O)c2N(C=O)C(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)CNc2[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C19 compound treatment 0.8571 -0.0112 -0.13 0.8839 0.012 0.18 0.0345 0.1544 3069535 BPBio1_000767 C(Nc1ncnc2nc[nH]c12)c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C20 compound treatment 0.8429 -0.0253 -0.3 0.8652 -0.00671 -0.1 -0.2816 -0.8968 953 BPBio1_000768 C[C@H](N)[C@H](O)c1ccc(O)c(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C21 compound treatment 0.8275 -0.0408 -0.48 0.8607 -0.0112 -0.17 -0.4579 -0.9016 3616773 BPBio1_000769 CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@H](C/C=C(\C)/C(O[C@H]4C[C@H](OC)C(O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2)C=C[C@@H]1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C22 compound treatment 0.8067 -0.0616 -0.72 0.8844 0.0126 0.19 -0.3776 -0.505 1531 BPBio1_000770 O=c1n([se]c2ccccc12)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C23 mock treatment 0.8733 0.00506 0.06 0.8993 0.0274 0.41 0.3337 0.8006 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 C24 mock treatment 0.9175 0.0492 0.58 0.8773 0.00544 0.08 0.4663 0.7992 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D01 compound treatment 0.968 0.0997 1.17 0.9257 0.0539 0.81 1.4001 0.9839 3189316 BPBio1_000771 COc1ccc(cc1)c2ccc(=N)n(CCCC(=O)O)n2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D02 compound treatment 0.8942 0.026 0.3 0.9104 0.0386 0.58 0.6255 0.9549 3614719 BPBio1_000772 C[C@@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]2CC[C@@H]1C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D03 compound treatment 0.9255 0.0572 0.67 0.8874 0.0155 0.23 0.6404 0.9002 3472295 BPBio1_000773 COc1c(O)cc2C(=O)OC3C(O)C(O)C(CO)OC3c2c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D04 compound treatment 0.9051 0.0368 0.43 0.862 -0.00988 -0.15 0.2005 0.4386 1022907 BPBio1_000774 CC(=O)c1cc2ccccc2oc1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D05 compound treatment 0.8863 0.0181 0.21 0.8725 6.41E-4 0.01 0.1567 0.7385 1446 BPBio1_000775 OC(COc1cccc2oc(cc(=O)c12)C(=O)O)COc3cccc4oc(cc(=O)c34)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D06 compound treatment 0.9117 0.0435 0.51 0.8628 -0.00904 -0.14 0.2646 0.5012 3616845 BPBio1_000776 OC[C@H]1OC(Oc2cc3ccc(=O)oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D07 compound treatment 0.874 0.00574 0.07 0.8449 -0.027 -0.41 -0.2394 -0.5819 3616827 BPBio1_000777 CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4OP(=O)(O)OC[C@H]4[C@H]3OC(=O)CCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D08 compound treatment 0.8642 -0.00411 -0.05 0.8684 -0.00349 -0.05 -0.0712 -0.9991 2776 BPBio1_000778 OC(=O)Cc1ccc(cc1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D09 compound treatment 0.8496 -0.0187 -0.22 0.8383 -0.0336 -0.51 -0.5121 -0.9302 3176931 BPBio1_000779 NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@@H](c4ccccc4)S(=O)(=O)O)C3=O)C(=O)O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D10 compound treatment 0.8859 0.0176 0.21 0.8715 -3.9E-4 -0.01 0.1422 0.6868 1012530 BPBio1_000780 CCCCOC(=O)c1ccc(O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D11 compound treatment 0.8563 -0.012 -0.14 0.8512 -0.0207 -0.31 -0.3196 -0.9358 717 BPBio1_000781 OC(=O)c1ccccc1OP(=O)(O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D12 compound treatment 0.866 -0.00228 -0.03 0.8457 -0.0262 -0.39 -0.2975 -0.7533 1299 BPBio1_000782 Nc1ccc(cc1)C(=O)NCC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D13 compound treatment 0.8808 0.0125 0.15 0.8662 -0.00565 -0.09 0.044 0.2587 1102 BPBio1_000783 CC(C(=O)O)c1ccc(cc1)C(=O)c2cccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D14 compound treatment 0.8482 -0.0201 -0.24 0.8558 -0.0161 -0.24 -0.338 -0.9999 1231 BPBio1_000784 CC(C)C[C@H](NC(=O)C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D15 compound treatment 0.8648 -0.00351 -0.04 0.8394 -0.0325 -0.49 -0.3745 -0.7641 1047041 BPBio1_000785 OC1Cc2c(O)cc(O)cc2OC1c3ccc(O)c(O)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D16 compound treatment 0.8409 -0.0274 -0.32 0.8374 -0.0345 -0.52 -0.594 -0.9737 1258 BPBio1_000786 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCNCC3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D17 compound treatment 0.8271 -0.0412 -0.48 0.8888 0.017 0.26 -0.1613 -0.2949 1555091 BPBio1_000787 CC(C)(C)NCC(O)COc1cccc2CC(O)C(O)Cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D18 compound treatment 0.8373 -0.031 -0.36 0.8583 -0.0135 -0.2 -0.4013 -0.9624 3059213 BPBio1_000788 COc1ccc(C(=O)c2ccccc2O)c(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D19 compound treatment 0.8533 -0.015 -0.18 0.842 -0.0298 -0.45 -0.4414 -0.9164 3066 BPBio1_000789 CO[C@]1(NC(=O)[C@H](C(=O)O)c2ccc(O)cc2)[C@H]3OCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D20 compound treatment 0.8215 -0.0468 -0.55 0.8404 -0.0315 -0.47 -0.7229 -0.9973 3187899 BPBio1_000790 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D21 compound treatment 0.8465 -0.0218 -0.26 0.8797 0.00787 0.12 -0.0974 -0.3453 856 BPBio1_000791 Cn1c(=O)n(C)c2nc[nH]c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D22 compound treatment 0.862 -0.0063 -0.07 0.864 -0.00786 -0.12 -0.1359 -0.9745 3616847 BPBio1_000792 C[N+]1(C)C2CC[C@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D23 mock treatment 0.8883 0.02 0.23 0.8495 -0.0224 -0.34 -0.072 -0.1754 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 D24 mock treatment 0.865 -0.00323 -0.04 0.876 0.00417 0.06 0.0176 0.2395 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E01 compound treatment 0.9213 0.053 0.62 0.9167 0.0448 0.67 0.9165 0.9992 2060389 BPBio1_000793 OC(=O)Cc1c[nH]cn1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E02 compound treatment 0.9336 0.0654 0.77 0.896 0.0241 0.36 0.799 0.9416 1220 BPBio1_000794 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E03 compound treatment 0.9313 0.0631 0.74 0.9085 0.0366 0.55 0.9126 0.9893 3069536 BPBio1_000795 OC[C@H]1OC([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3c(=O)cc(oc23)c4ccc(O)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E04 compound treatment 0.9135 0.0452 0.53 0.8746 0.00273 0.04 0.4042 0.7595 1000108 BPBio1_000796 NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E05 compound treatment 0.8798 0.0115 0.14 0.8917 0.0199 0.3 0.3071 0.9359 3616774 BPBio1_000797 CN1C[C@@]2(C=C)C3CC4OC[C@@H]3[C@@H]1[C@H]2[C@@]45C(=O)Nc6ccccc65 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E06 compound treatment 0.8917 0.0234 0.27 0.8691 -0.00271 -0.04 0.1656 0.5957 799 BPBio1_000798 Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E07 compound treatment 0.8956 0.0273 0.32 0.8384 -0.0334 -0.5 -0.1289 -0.216 3616775 BPBio1_000799 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@]61CC[C@@H](C)CN6 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E08 compound treatment 0.8641 -0.00418 -0.05 0.824 -0.0479 -0.72 -0.5438 -0.7535 3187753 BPBio1_000800 C[C@H]1C[C@H]2[C@@H]3CC[C@H](C(=O)C)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)CCC(=O)C=C14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E09 compound treatment 0.8551 -0.0132 -0.16 0.8538 -0.0181 -0.27 -0.3016 -0.9648 3616777 BPBio1_000801 CCN1C[C@]2(COC)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](OC)[C@@H]4[C@@]6(C[C@@H]5OC)OCO[C@]76[C@@H](O)[C@@H]32)C17 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E10 compound treatment 0.8688 4.97E-4 0.01 0.8487 -0.0231 -0.35 -0.2418 -0.6951 3187754 BPBio1_000802 CNCC(O)C(O)C(O)C(O)CO.Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E11 compound treatment 0.883 0.0147 0.17 0.8485 -0.0233 -0.35 -0.1259 -0.3216 3616778 BPBio1_000803 COc1c(OC[C@@H](O)C(C)(C)O)ccc2c(OC)c3ccoc3nc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E12 compound treatment 0.9032 0.0349 0.41 0.8656 -0.00625 -0.09 0.2235 0.5313 3187755 BPBio1_000804 CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C/C=C/C=C/[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E13 compound treatment 0.8942 0.0259 0.3 0.8523 -0.0196 -0.29 0.0066 0.0156 3187620 BPBio1_000805 C[C@H]1CCC[C@@H](C)N1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E14 compound treatment 0.8868 0.0185 0.22 0.8939 0.022 0.33 0.3877 0.9789 3069580 BPBio1_000806 C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E15 compound treatment 0.8824 0.0141 0.17 0.8564 -0.0154 -0.23 -0.047 -0.1649 1540789 BPBio1_000807 COc1cc(=O)n(C)c2c(OCC(O)C(C)(C)O)cccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E16 compound treatment 0.8768 0.00852 0.1 0.8477 -0.0242 -0.36 -0.1863 -0.4942 3069581 BPBio1_000808 Cn1nnnc1SCC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@H](O)c4ccccc4)C3=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E17 compound treatment 0.835 -0.0332 -0.39 0.8341 -0.0378 -0.57 -0.6773 -0.9832 1054505 BPBio1_000809 COc1ccc2c(OC)c3ccoc3nc2c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E18 compound treatment 0.889 0.0207 0.24 0.923 0.0511 0.77 0.7156 0.8874 3616814 BPBio1_000810 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)[C@@H](OC)[C@H](C)C(=O)O)O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)[C@H](C)C[C@@H]5C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E19 compound treatment 0.8675 -7.49E-4 -0.01 0.8867 0.0148 0.22 0.1512 0.6787 3616780 BPBio1_000811 C1CC[C@@H](NC1)c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E20 compound treatment 0.8492 -0.0191 -0.22 0.8427 -0.0292 -0.44 -0.4691 -0.9513 4338 BPBio1_000812 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E21 compound treatment 0.8427 -0.0256 -0.3 0.8987 0.0269 0.4 0.0732 0.1452 193 BPBio1_000813 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E22 compound treatment 0.8709 0.00262 0.03 0.8732 0.00134 0.02 0.036 0.9792 1050972 BPBio1_000814 CC1(O)CCOC(=O)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E23 mock treatment 0.8583 -0.00999 -0.12 0.871 -8.35E-4 -0.01 -0.0918 -0.7784 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 E24 mock treatment 0.9087 0.0404 0.47 0.9011 0.0292 0.44 0.6458 0.9993 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F01 compound treatment 0.9691 0.101 1.18 0.9459 0.074 1.11 1.6236 0.9995 3614716 BPBio1_000815 Cc1ncsc1CCCl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F02 compound treatment 0.9338 0.0656 0.77 0.9023 0.0305 0.46 0.8682 0.9694 3614720 BPBio1_000816 CC(C)(C)C1(COP2(=S)OC1)CO2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F03 compound treatment 0.9068 0.0385 0.45 0.8625 -0.00932 -0.14 0.2203 0.4658 3616829 BPBio1_000817 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c4ccccc4)C(=O)N2[C@H]1C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F04 compound treatment 0.8976 0.0293 0.34 0.8588 -0.0131 -0.2 0.1044 0.2634 2732 BPBio1_000818 Cc1cc(=O)oc2cc(O)ccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F05 compound treatment 0.9016 0.0334 0.39 0.8567 -0.0152 -0.23 0.1156 0.2551 1303 BPBio1_000819 C[N+]1(CCC2CC1)CC2OC(=O)C(O)(c3ccccc3)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F06 compound treatment 0.9127 0.0444 0.52 0.8653 -0.00653 -0.1 0.2991 0.5639 1978 BPBio1_000820 OC(=O)/C=C/c1ccc(O)c(O)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F07 compound treatment 0.8709 0.00267 0.03 0.853 -0.0188 -0.28 -0.1779 -0.625 1529 BPBio1_000821 COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F08 compound treatment 0.87 0.00172 0.02 0.8604 -0.0115 -0.17 -0.1078 -0.6203 3069737 BPBio1_000822 CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F09 compound treatment 0.8672 -0.00106 -0.01 0.8682 -0.00364 -0.05 -0.0475 -0.8465 1114 BPBio1_000823 NS(=O)(=O)c1cc2c(N=C(CSCc3ccccc3)NS2(=O)=O)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F10 compound treatment 0.8776 0.00934 0.11 0.8594 -0.0125 -0.19 -0.0554 -0.2544 2743 BPBio1_000824 CC(C)(C(=O)c1cccnc1)c2cccnc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F11 compound treatment 0.8809 0.0126 0.15 0.867 -0.0049 -0.07 0.0529 0.3191 1000 BPBio1_000825 NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F12 compound treatment 0.8932 0.025 0.29 0.8491 -0.0227 -0.34 -0.0347 -0.077 3202 BPBio1_000826 COc1ccccc1N2CCN(CCCNc3cc(=O)n(C)c(=O)n3C)CC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F13 compound treatment 0.8679 -3.95E-4 0.0 0.8586 -0.0133 -0.2 -0.1448 -0.7233 1052436 BPBio1_000827 CCN(CC)CCc1nc(no1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F14 compound treatment 0.8913 0.023 0.27 0.8586 -0.0133 -0.2 0.0493 0.1469 23081 BPBio1_000828 Fc1ccc(cc1)C(CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4)c5ccc(F)cc5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F15 compound treatment 0.8631 -0.00514 -0.06 0.8371 -0.0348 -0.52 -0.4126 -0.7835 1397 BPBio1_000829 CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F16 compound treatment 0.8474 -0.0209 -0.25 0.8552 -0.0167 -0.25 -0.351 -0.9999 1472 BPBio1_000830 CC(C)Cc1ccc(cc1)[C@H](C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F17 compound treatment 0.8431 -0.0251 -0.3 0.84 -0.0319 -0.48 -0.5475 -0.9729 3187885 BPBio1_000831 CC[C@H]([C@H]1O[C@@](CC)(C[C@@H]1C)[C@H]2CC[C@](O)(CC)[C@H](C)O2)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F18 compound treatment 0.867 -0.00131 -0.02 0.8588 -0.013 -0.2 -0.1496 -0.7602 3187900 BPBio1_000832 CC(=O)O[C@H]1CC[C@@H]2[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]4(OC(=O)C)C#C)[C@@H]3CCC2=C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F19 compound treatment 0.8743 0.00602 0.07 0.8589 -0.013 -0.2 -0.0882 -0.4246 1519 BPBio1_000833 CC1(C)OC(=O)NC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F20 compound treatment 0.8616 -0.00666 -0.08 0.8779 0.00599 0.09 0.0084 0.0707 1440 BPBio1_000834 COc1ccc2cc(CCC(=O)C)ccc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F21 compound treatment 0.8616 -0.00668 -0.08 0.8843 0.0125 0.19 0.0771 0.3794 852 BPBio1_000835 CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F22 compound treatment 0.8558 -0.0125 -0.15 0.8523 -0.0196 -0.29 -0.3118 -0.9477 907434 BPBio1_000836 CNCCC(Oc1ccccc1OC)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F23 mock treatment 0.8646 -0.00369 -0.04 0.854 -0.0179 -0.27 -0.2206 -0.8107 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 F24 mock treatment 0.894 0.0257 0.3 0.8518 -0.0201 -0.3 2.0E-4 5.0E-4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G01 compound treatment 0.9406 0.0723 0.85 0.909 0.0372 0.56 0.9956 0.9795 399 BPBio1_000837 Nc1nc2ccc(OC(F)(F)F)cc2s1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G02 compound treatment 0.9284 0.0602 0.71 0.8961 0.0243 0.36 0.7573 0.9529 3684 BPBio1_000838 OC(=O)C1=CCCNC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G03 compound treatment 0.9052 0.0369 0.43 0.9034 0.0315 0.47 0.6413 0.999 3129 BPBio1_000839 CC(=O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4(C)[C@@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G04 compound treatment 0.863 -0.00532 -0.06 0.874 0.00212 0.03 -0.0216 -0.3088 3480633 BPBio1_000840 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G05 compound treatment 0.9152 0.047 0.55 0.871 -8.24E-4 -0.01 0.381 0.691 1025381 BPBio1_000841 COc1ccc2CC3N(CCc4cc5OCOc5cc34)Cc2c1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G06 compound treatment 0.8959 0.0277 0.32 0.8555 -0.0163 -0.25 0.0559 0.1373 1404 BPBio1_000842 Nc1ccc(N=Nc2ccccc2)c(N)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G07 compound treatment 0.8798 0.0115 0.14 0.8353 -0.0366 -0.55 -0.2934 -0.5179 3616781 BPBio1_000843 CCN1C[C@]2(C)CC[C@H](OC)[C@@]34[C@@H]2[C@H](OC(=O)C)[C@@]5(OCO[C@]65C[C@H](OC)[C@H]7C[C@]4(O)[C@@H]6[C@H]7OC)C13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G08 compound treatment 0.8638 -0.00452 -0.05 0.8569 -0.0149 -0.22 -0.1962 -0.8508 1451 BPBio1_000844 CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G09 compound treatment 0.8731 0.00478 0.06 0.8716 -2.97E-4 0.0 0.0365 0.6487 1182082 BPBio1_000845 Cn1c(cc(=O)c2ccccc12)c3ccc4OCOc4c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G10 compound treatment 0.8833 0.015 0.18 0.8502 -0.0217 -0.33 -0.106 -0.2859 1438 BPBio1_000846 CC(C(=O)O)c1cccc(Oc2ccccc2)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G11 compound treatment 0.8955 0.0272 0.32 0.8604 -0.0115 -0.17 0.104 0.2862 3616783 BPBio1_000847 CN1CCC2=C[C@H](O)[C@H]3OC(=O)c4cc5OCOc5cc4[C@H]3[C@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G12 compound treatment 0.8724 0.00414 0.05 0.8288 -0.0431 -0.65 -0.424 -0.6522 963 BPBio1_000848 CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4)C(=O)C1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G13 compound treatment 0.8546 -0.0136 -0.16 0.8183 -0.0536 -0.81 -0.683 -0.8313 3187623 BPBio1_000849 CC=C(C)C(=O)OC1[C@H](OC(=O)C)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(OC6OC([C@H](O[C@H]7OC(CO)[C@H](O)[C@H](O)C7O)[C@H](O)C6O[C@H]8OC(CO)[C@H](O)[C@H](O)C8O)C(=O)O)[C@](C)(CO)C5CCC43C)C2CC1(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G14 compound treatment 0.8843 0.016 0.19 0.854 -0.0178 -0.27 -0.0568 -0.1735 1138 BPBio1_000850 CC/C(=C(/CC)\c1ccc(O)cc1)/c2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G15 compound treatment 0.8822 0.0139 0.16 0.8477 -0.0241 -0.36 -0.1416 -0.3558 829 BPBio1_000851 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G16 compound treatment 0.8704 0.00212 0.02 0.8483 -0.0235 -0.35 -0.2325 -0.6558 3057880 BPBio1_000852 COc1ccc(cc1)C(=C(c2ccc(OC)cc2)c3ccc(OC)cc3)Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G17 compound treatment 0.8774 0.00909 0.11 0.8432 -0.0287 -0.43 -0.2292 -0.5163 1115322 BPBio1_000853 COc1ccn(C)c(=O)c1C#N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G18 compound treatment 2.3193 1.45 17.03 1.4196 0.548 8.24 17.8665 0.9444 3616815 BPBio1_000854 NC[C@H]1O[C@H](OC2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G19 compound treatment 0.8586 -0.00964 -0.11 0.8239 -0.048 -0.72 -0.5902 -0.8081 3616785 BPBio1_000855 CCN1C[C@]2(COC)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](OC)[C@@H]4[C@](O)(C[C@@H]5OC)[C@@]6(O)[C@@H](OC)[C@@H]32)C16 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G20 compound treatment 0.8679 -3.5E-4 0.0 0.83 -0.0419 -0.63 -0.4479 -0.7117 1094620 BPBio1_000856 CC(C[N+](C)(C)C)OC(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G21 compound treatment 0.8708 0.00248 0.03 0.8556 -0.0162 -0.24 -0.1519 -0.6183 3616786 BPBio1_000857 C/C=C\1/C[N+]2(C)CCC34[C@@H]2C[C@@H]1C(=C4Nc5ccccc53)C=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G22 compound treatment 0.8658 -0.00244 -0.03 0.8394 -0.0325 -0.49 -0.3654 -0.7472 1246 BPBio1_000858 CC[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G23 mock treatment 0.85 -0.0183 -0.21 0.8784 0.00658 0.1 -0.0818 -0.3461 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 G24 mock treatment 0.8556 -0.0127 -0.15 0.8552 -0.0166 -0.25 -0.2822 -0.9695 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H01 compound treatment 0.9399 0.0716 0.84 0.9161 0.0442 0.67 1.0649 0.9933 962 BPBio1_000859 CCC1(C(=O)NCNC1=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H02 compound treatment 0.9284 0.0601 0.71 0.9025 0.0306 0.46 0.8244 0.9787 1008060 BPBio1_000860 C1CCc2nnnn2CC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H03 compound treatment 0.9263 0.058 0.68 0.866 -0.00584 -0.09 0.4191 0.6108 1452 BPBio1_000861 CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H04 compound treatment 0.9209 0.0526 0.62 0.8777 0.00588 0.09 0.4993 0.8002 3616848 BPBio1_000862 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1.O[C@H]([C@@H](O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H05 compound treatment 0.8756 0.00735 0.09 0.8443 -0.0275 -0.41 -0.2318 -0.548 1189 BPBio1_000863 CO[C@]1(NC(=O)Cc2cccs2)[C@H]3SCC(=C(N3C1=O)C(=O)O)COC(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H06 compound treatment 0.9848 0.117 1.37 0.9725 0.101 1.51 2.037 0.9987 1001471 BPBio1_000864 Oc1ccc(OCc2ccccc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H07 compound treatment 0.9019 0.0336 0.39 0.8634 -0.00844 -0.13 0.1891 0.4565 1000080 BPBio1_000865 ClCCNP1(=O)OCCCN1CCCl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H08 compound treatment 0.8882 0.0199 0.23 0.839 -0.0329 -0.49 -0.1844 -0.3375 1025776 BPBio1_000866 Nc1ccccc1S(=O)(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H09 compound treatment 0.8869 0.0186 0.22 0.8152 -0.0567 -0.85 -0.4484 -0.5095 3616830 BPBio1_000867 CO[C@@H]1[C@@H](OC(=O)N)[C@@H](O)C(Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H10 compound treatment 0.8986 0.0303 0.36 0.8559 -0.016 -0.24 0.0814 0.1895 3060043 BPBio1_000868 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H11 compound treatment 0.8912 0.0229 0.27 0.8387 -0.0331 -0.5 -0.1622 -0.2867 1232 BPBio1_000869 OC1=C(O)C(=O)C(=C(O)C1=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H12 compound treatment 0.8922 0.0239 0.28 0.8545 -0.0173 -0.26 0.0139 0.0364 907370 BPBio1_000870 CCCCCN(CCCCC)C(=O)C(CCC(=O)O)NC(=O)c1ccc(Cl)c(Cl)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H13 compound treatment 0.8736 0.00528 0.06 0.8364 -0.0355 -0.53 -0.3335 -0.6208 1029 BPBio1_000871 CC(C(=O)O)c1ccc(cc1)N2Cc3ccccc3C2=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H14 compound treatment 0.8654 -0.00293 -0.03 0.8444 -0.0275 -0.41 -0.3164 -0.7633 117 BPBio1_000872 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H15 compound treatment 0.8437 -0.0246 -0.29 0.8359 -0.036 -0.54 -0.5865 -0.9568 1276 BPBio1_000873 CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O)OC(=O)CCC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H16 compound treatment 0.8607 -0.00755 -0.09 0.8814 0.00954 0.14 0.0388 0.2303 1000135 BPBio1_000874 CC(C(=O)O)c1ccc(c(F)c1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H17 compound treatment 1.8665 0.998 11.72 1.2789 0.407 6.12 12.6128 0.9542 3187887 BPBio1_000875 CC(CN(C(=O)C)c1c(I)cc(I)c(N)c1I)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H18 compound treatment 0.8566 -0.0117 -0.14 0.8334 -0.0385 -0.58 -0.5061 -0.8509 115 BPBio1_000876 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H19 compound treatment 0.8525 -0.0157 -0.18 0.8581 -0.0138 -0.21 -0.2772 -0.9984 1670 BPBio1_000877 Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H20 compound treatment 0.8459 -0.0224 -0.26 0.8691 -0.00279 -0.04 -0.2158 -0.8097 3221506 BPBio1_000878 CCC(C)C(N)C1=NC(CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(=O)N)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H21 compound treatment 0.8636 -0.00472 -0.06 0.8561 -0.0157 -0.24 -0.2063 -0.8498 727 BPBio1_000879 CCN(CC)C(C)CN1c2ccccc2Sc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H22 compound treatment 0.8781 0.00978 0.11 0.872 1.58E-4 0.0 0.0828 0.7216 3616849 BPBio1_000880 O[C@@H]1CCCC[C@H]1N2CCC(CC2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H23 mock treatment 0.8695 0.00127 0.01 0.8734 0.00151 0.02 0.0266 0.979 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 H24 mock treatment 0.8474 -0.0209 -0.25 0.8654 -0.00642 -0.1 -0.2417 -0.9171 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I01 compound treatment 0.9585 0.0902 1.06 0.9288 0.0569 0.86 1.3539 0.9944 3061090 BPBio1_000881 OC(=O)C1CCCN(CCC=C(c2ccccc2)c3ccccc3)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I02 compound treatment 0.9446 0.0764 0.9 0.8957 0.0238 0.36 0.8874 0.9192 774 BPBio1_000882 OC(=O)C1=CCNCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I03 compound treatment 0.9362 0.0679 0.8 0.9113 0.0394 0.59 0.9825 0.9894 3069541 BPBio1_000883 C[C@H]1[C@H]2[C@H](OC1=O)[C@H]3C(=CC(=O)C3=C(C)C[C@@H]2O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I04 compound treatment 0.9161 0.0478 0.56 0.883 0.0111 0.17 0.5152 0.8799 1429 BPBio1_000884 CCCCOC(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I05 compound treatment 0.942 0.0737 0.86 0.8635 -0.0084 -0.13 0.5222 0.5975 3616789 BPBio1_000885 CC[N+]1(C)[C@H]2CC[C@@H]1CC(C2)OC(=O)[C@H]3CCC(C(=O)OC4C[C@@H]5CC[C@H](C4)[N+]5(C)CC)(c6ccccc6)c7ccccc37 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I06 compound treatment 0.8994 0.0311 0.36 0.8314 -0.0404 -0.61 -0.172 -0.2426 867 BPBio1_000886 Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I07 compound treatment 0.8839 0.0157 0.18 0.8508 -0.021 -0.32 -0.0935 -0.2556 3173628 BPBio1_000887 CN1C(C)(C)CCCC1(C)C.OC(C(O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I08 compound treatment 0.8786 0.0103 0.12 0.8389 -0.033 -0.5 -0.2652 -0.5194 1001 BPBio1_000888 CN(C)CCOC(=O)COc1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I09 compound treatment 0.8894 0.0212 0.25 0.8524 -0.0194 -0.29 -0.0311 -0.0809 3616793 BPBio1_000889 CO[C@H](C)C(O)(C(C)C)C(=O)OCC1=CCN2CC[C@H](O)[C@H]21 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I10 compound treatment 0.8619 -0.0064 -0.08 0.811 -0.0608 -0.92 -0.7002 -0.7626 3069584 BPBio1_000890 [O-][N+](=O)c1ccc(/C=N/N2CC(CN3CCOCC3)OC2=O)o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I11 compound treatment 0.8749 0.00662 0.08 0.8263 -0.0456 -0.69 -0.4298 -0.6229 3616795 BPBio1_000891 C1CN[C@H]2[C@@H](C1)C3CCC2[C@H]4N3CCc5c4[nH]c6ccccc56 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I12 compound treatment 0.8661 -0.00222 -0.03 0.8276 -0.0443 -0.67 -0.4891 -0.7342 837 BPBio1_000892 CCOc1ccc2NC(C)(C)C=C(C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I13 compound treatment 0.9587 0.0904 1.06 0.9479 0.076 1.14 1.5583 0.9993 3069543 BPBio1_000893 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H](C32)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I14 compound treatment 0.8676 -6.48E-4 -0.01 0.8222 -0.0496 -0.75 -0.5333 -0.7143 2575 BPBio1_000894 CCS(=O)(=O)CCn1c(C)ncc1[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I15 compound treatment 0.8575 -0.0108 -0.13 0.8344 -0.0375 -0.56 -0.488 -0.8452 3616797 BPBio1_000895 CCN1C[C@]2(C)CC[C@H](O)[C@]3([C@@H]4C[C@H]5C(O)[C@@H]4[C@](O)(C[C@@H]5OC)[C@H]6C[C@@H]32)C61 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I16 compound treatment 0.8761 0.00784 0.09 0.8249 -0.047 -0.71 -0.4343 -0.6099 3187758 BPBio1_000896 NC(=N)NCC1COC2(CCCCC2)O1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I17 compound treatment 0.8462 -0.0221 -0.26 0.8356 -0.0363 -0.55 -0.5692 -0.9422 3187745 BPBio1_000897 C[C@@]12CC[C@H]3[C@@H](CCc4cc(OS(=O)(=O)O)ccc34)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I18 compound treatment 0.858 -0.0103 -0.12 0.8271 -0.0447 -0.67 -0.5609 -0.8205 3616817 BPBio1_000898 Nc1ncnc2n(cnc12)C3O[C@H](CO)[C@@H](O)[C@@H]3O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I19 compound treatment 0.8317 -0.0365 -0.43 0.8394 -0.0325 -0.49 -0.6487 -0.9979 3616800 BPBio1_000899 CO[C@H]1C=C2CCN(C)[C@H]2C3[C@@H]1OC(=O)c4cc5OCOc5cc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I20 compound treatment 0.8485 -0.0198 -0.23 0.8349 -0.037 -0.56 -0.5575 -0.9253 1094 BPBio1_000900 COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I21 compound treatment 0.8576 -0.0107 -0.13 0.8556 -0.0162 -0.24 -0.2617 -0.9526 3616802 BPBio1_000901 CCN1C[C@]2(C)CC[C@H](O)[C@]3([C@@H]2C[C@H]4C13)[C@@H]5C[C@H](O)[C@H]6C[C@]45[C@H](O)C6=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I22 compound treatment 0.8408 -0.0275 -0.32 0.8481 -0.0237 -0.36 -0.4803 -0.9987 888 BPBio1_000902 CC(C)[N+](C)(CCC(C(=O)N)(c1ccccc1)c2ccccc2)C(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I23 mock treatment 0.8271 -0.0412 -0.48 0.8742 0.00233 0.03 -0.3169 -0.6542 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 I24 mock treatment 0.8577 -0.0106 -0.12 0.846 -0.0259 -0.39 -0.3635 -0.8886 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J01 compound treatment 0.9621 0.0938 1.1 0.9206 0.0488 0.73 1.2975 0.9805 3614717 BPBio1_000903 NCCn1oc(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J02 compound treatment 0.9391 0.0708 0.83 0.8918 0.0199 0.3 0.7995 0.905 3614721 BPBio1_000904 OC/C=C/C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J03 compound treatment 0.9571 0.0888 1.04 0.8923 0.0204 0.31 0.9539 0.878 3187888 BPBio1_000905 O=C1OC2(C[C@H]3C=CC2=C1)[C@H]4CCCCN34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J04 compound treatment 0.9203 0.052 0.61 0.8825 0.0107 0.16 0.5449 0.8635 1637 BPBio1_000906 CN/C(=C/[N+](=O)[O-])/NCCSCc1csc(CN(C)C)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J05 compound treatment 0.9103 0.042 0.49 0.8266 -0.0453 -0.68 -0.1329 -0.1579 3044756 BPBio1_000907 CC(CN(C)C)CN1c2ccccc2Sc3ccccc13.OC(C(O)C(=O)O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J06 compound treatment 0.9102 0.042 0.49 0.8279 -0.044 -0.66 -0.1197 -0.1451 3188017 BPBio1_000908 S=C(NC1CCCCC1)N2CCC(CC2)C3C=NC=N3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J07 compound treatment 0.8955 0.0272 0.32 0.8562 -0.0156 -0.23 0.0596 0.1504 3187889 BPBio1_000909 CCOc1ccc2ccccc2c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J08 compound treatment 0.8955 0.0272 0.32 0.8404 -0.0314 -0.47 -0.108 -0.1893 3061617 BPBio1_000910 OC(CNCCNC(=O)N1CCOCC1)COc2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J09 compound treatment 0.909 0.0407 0.48 0.8462 -0.0257 -0.39 0.0649 0.1056 1057 BPBio1_000911 OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J10 compound treatment 0.8732 0.0049 0.06 0.8446 -0.0272 -0.41 -0.2488 -0.6018 1000092 BPBio1_000912 COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J11 compound treatment 0.8413 -0.027 -0.32 0.7987 -0.0732 -1.1 -1.0022 -0.8749 3074401 BPBio1_000913 CN(C)CCCO[C@H]1[C@H](O[C@@H]2OC(C)(C)O[C@H]12)[C@H](O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J12 compound treatment 0.8493 -0.019 -0.22 0.8322 -0.0397 -0.6 -0.5796 -0.9097 1007994 BPBio1_000914 CCCCCCCCCCCCCCCC[N+](C)(C)CCN(Cc1ccc(OC)cc1)c2ncccn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J13 compound treatment 0.8673 -9.4E-4 -0.01 0.8098 -0.0621 -0.93 -0.6678 -0.7154 2710 BPBio1_000915 COc1ccc2[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]4(O)C#C)[C@@H]3CCc2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J14 compound treatment 0.878 0.00977 0.11 0.8438 -0.0281 -0.42 -0.2177 -0.4972 3060036 BPBio1_000916 C1CN=C(N1)C2COc3ccccc3O2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J15 compound treatment 0.8588 -0.00945 -0.11 0.836 -0.0359 -0.54 -0.4602 -0.835 3452 BPBio1_000917 CC(C)(C)NC[C@H](O)COc1cccc2C(=O)CCCc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J16 compound treatment 0.8422 -0.0261 -0.31 0.7955 -0.0763 -1.15 -1.0281 -0.8655 2844 BPBio1_000918 CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J17 compound treatment 0.8412 -0.0271 -0.32 0.8305 -0.0413 -0.62 -0.6643 -0.9515 3487254 BPBio1_000919 CC(=O)N(CC(O)CN(C(=O)C)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I)c2c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c2I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J18 compound treatment 0.8299 -0.0384 -0.45 0.8373 -0.0345 -0.52 -0.6858 -0.9975 1765 BPBio1_000920 CC1(C)NC(=O)N(C1=O)c2ccc([N+](=O)[O-])c(c2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J19 compound treatment 0.8427 -0.0256 -0.3 0.8461 -0.0258 -0.39 -0.4868 -0.9921 3069696 BPBio1_000921 CN(C)[C@H]1C2CC3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)NCN4CCCC4)C(=O)c5c(O)cccc5[C@@]3(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J20 compound treatment 0.8374 -0.0309 -0.36 0.862 -0.00985 -0.15 -0.3613 -0.9219 3172846 BPBio1_000922 NC(CO)(CO)CO.OC(=O)C1CCn2c(ccc12)C(=O)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J21 compound treatment 0.8385 -0.0298 -0.35 0.8563 -0.0156 -0.23 -0.4126 -0.981 1405 BPBio1_000923 C[C@@]12CC[C@H]3C(=CCc4cc(O)ccc34)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J22 compound treatment 0.8488 -0.0194 -0.23 0.8599 -0.0119 -0.18 -0.2881 -0.9929 4487 BPBio1_000924 CNCCCC1c2ccccc2C=Cc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J23 mock treatment 0.8366 -0.0316 -0.37 0.8591 -0.0128 -0.19 -0.3983 -0.9528 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 J24 mock treatment 0.8492 -0.0191 -0.22 0.8722 3.45E-4 0.01 -0.1547 -0.6905 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K01 compound treatment 0.9814 0.113 1.33 0.9373 0.0654 0.98 1.6348 0.9891 1002022 BPBio1_000925 NC(CCC(=O)O)C=C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K02 compound treatment 0.9508 0.0825 0.97 0.9068 0.0349 0.53 1.0561 0.9586 2178 BPBio1_000926 NCc1cc(O)no1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K03 compound treatment 0.9391 0.0709 0.83 0.8794 0.00753 0.11 0.6681 0.7961 3616804 BPBio1_000927 COc1cc(ccc1O)C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K04 compound treatment 0.8364 -0.0319 -0.37 0.841 -0.0308 -0.46 -0.5926 -0.9944 3187759 BPBio1_000928 CCC(=O)OCC(=O)C1(OC(=O)CC)[C@H](C)C[C@H]2[C@@H]3[C@H](Cl)CC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K05 compound treatment 0.9021 0.0338 0.4 0.8366 -0.0353 -0.53 -0.0944 -0.1426 3480066 BPBio1_000929 CN(C)CCCC1(OCc2cc(C#N)ccc21)c3ccc(F)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K06 compound treatment 0.8961 0.0279 0.33 0.8436 -0.0282 -0.42 -0.0692 -0.1291 1499 BPBio1_000930 Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K07 compound treatment 0.8804 0.0122 0.14 0.8472 -0.0247 -0.37 -0.1616 -0.4063 1047 BPBio1_000931 CN(C)CCCN1c2ccccc2Sc3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K08 compound treatment 0.921 0.0527 0.62 0.8379 -0.034 -0.51 0.0763 0.0951 3069624 BPBio1_000932 CC[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]2CC[C@@]1(O)C#C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K09 compound treatment 0.918 0.0497 0.58 0.843 -0.0289 -0.43 0.1052 0.1446 1177 BPBio1_000933 Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K10 compound treatment 0.7678 -0.1 -1.18 0.7795 -0.0924 -1.39 -1.8162 -0.9967 3187760 BPBio1_000934 CC(=O)OCC(=O)[C@]12OC(C)(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@@]31C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K11 compound treatment 0.8652 -0.00311 -0.04 0.8441 -0.0278 -0.42 -0.3215 -0.766 1463 BPBio1_000935 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K12 compound treatment 0.8596 -0.00872 -0.1 0.8169 -0.0549 -0.83 -0.6564 -0.7887 934 BPBio1_000936 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K13 compound treatment 0.8624 -0.00593 -0.07 0.8126 -0.0593 -0.89 -0.6796 -0.76 1424515 BPBio1_000937 CCN1C(=O)NC(C1=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K14 compound treatment 0.8587 -0.00962 -0.11 0.8069 -0.0649 -0.98 -0.7705 -0.7837 896 BPBio1_000938 COc1ccccc1OCC(O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K15 compound treatment 0.8471 -0.0212 -0.25 0.7935 -0.0784 -1.18 -1.0096 -0.838 3069570 BPBio1_000939 C[C@@]12CCC3[C@@H](CC[C@@H]4C[C@H](O)CC[C@@]43C)[C@@H]2CCC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K16 compound treatment 0.9815 0.113 1.33 0.9069 0.0351 0.53 1.3127 0.9181 1324 BPBio1_000940 CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K17 compound treatment 0.8433 -0.0249 -0.29 0.823 -0.0488 -0.73 -0.7263 -0.9186 1444 BPBio1_000941 C1CN=C(N1)C2CCCc3ccccc23 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K18 compound treatment 0.8268 -0.0415 -0.49 0.8429 -0.0289 -0.43 -0.6516 -0.9984 1338 BPBio1_000942 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K19 compound treatment 0.8357 -0.0326 -0.38 0.8593 -0.0126 -0.19 -0.4041 -0.9471 1070 BPBio1_000943 CCC(C(CC)c1ccc(O)cc1)c2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K20 compound treatment 0.819 -0.0492 -0.58 0.8597 -0.0122 -0.18 -0.5383 -0.8878 1533 BPBio1_000944 Cc1cc(CC(=O)O)n(C)c1C(=O)c2ccc(Cl)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K21 compound treatment 0.833 -0.0353 -0.41 0.8505 -0.0214 -0.32 -0.5203 -0.9922 1000312 BPBio1_000945 CO[C@]1(NC(=O)CSCC#N)[C@H]2SCC(=C(N2C1=O)C(=O)O)CSc3nnnn3C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K22 compound treatment 0.8634 -0.00485 -0.06 0.842 -0.0298 -0.45 -0.3574 -0.7906 956 BPBio1_000946 CCn1nc(C(=O)O)c(=O)c2cc3OCOc3cc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K23 mock treatment 0.8641 -0.00416 -0.05 0.8458 -0.0261 -0.39 -0.3117 -0.7891 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 K24 mock treatment 0.8768 0.00848 0.1 0.8684 -0.00347 -0.05 0.0334 0.2972 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L01 compound treatment 0.9904 0.122 1.43 0.9367 0.0648 0.97 1.7028 0.9823 2060391 BPBio1_000947 OC1/C(=C/C(=O)O)/CCCc2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L02 compound treatment 0.9789 0.111 1.3 0.9306 0.0587 0.88 1.5422 0.9824 907433 BPBio1_000948 OC(=O)C1=CCCN(CCON=C(c2ccccc2)c3ccccc3)C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L03 compound treatment 0.9589 0.0906 1.06 0.9054 0.0335 0.5 1.1085 0.9418 3197 BPBio1_000949 Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L04 compound treatment 0.9035 0.0352 0.41 0.8875 0.0157 0.24 0.4585 0.9647 1677 BPBio1_000950 CC(C)c1cccc(C(C)C)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L05 compound treatment 0.923 0.0547 0.64 0.876 0.00414 0.06 0.4982 0.772 3187892 BPBio1_000951 C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=C(C(=O)N)C(=O)C3(O)C(=C2C(=O)c4c(O)cccc14)O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L06 compound treatment 0.8722 0.0039 0.05 0.8163 -0.0555 -0.83 -0.5579 -0.6673 3560914 BPBio1_000952 CCN1CCC[C@H]1CNC(=O)c2c(O)c(CC)cc(Cl)c2OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L07 compound treatment 0.8918 0.0236 0.28 0.8549 -0.017 -0.26 0.0148 0.0394 1000323 BPBio1_000953 N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L08 compound treatment 0.9364 0.0681 0.8 0.863 -0.00889 -0.13 0.471 0.5808 962 BPBio1_000954 CCC1(C(=O)NCNC1=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L09 compound treatment 0.9204 0.0521 0.61 0.8364 -0.0354 -0.53 0.0561 0.0692 3616837 BPBio1_000955 CC[C@H]1OC(=O)[C@H](C)[C@@H](OC2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)/C(=N\OCOCCOC)/[C@H](C)[C@@H](O)[C@]1(C)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L10 compound treatment 0.8981 0.0298 0.35 0.8191 -0.0528 -0.79 -0.3143 -0.3623 1910 BPBio1_000956 Nc1nc(=O)[nH]cc1F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L11 compound treatment 0.7914 -0.0769 -0.9 0.7951 -0.0768 -1.15 -1.4546 -0.9925 1000270 BPBio1_000957 CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L12 compound treatment 0.8636 -0.00468 -0.05 0.7872 -0.0846 -1.27 -0.9386 -0.7369 3069740 BPBio1_000958 C[C@]1(N[C@H]2Cc3ccccc31)c4ccccc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L13 compound treatment 0.8727 0.00441 0.05 0.804 -0.0679 -1.02 -0.6851 -0.6704 865 BPBio1_000959 Cc1ccc(cc1)C(=O)c2ccc(CC(=O)O)n2C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L14 compound treatment 0.8594 -0.00885 -0.1 0.7974 -0.0745 -1.12 -0.8653 -0.7694 3616850 BPBio1_000960 C[N+](C)(CCOc1ccccc1)Cc2ccccc2.OC(=O)c1cc2ccccc2cc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L15 compound treatment 0.84 -0.0283 -0.33 0.8124 -0.0595 -0.89 -0.8672 -0.9089 3069698 BPBio1_000961 CC(C)(C)NC[C@@H](O)COc1cccc2C(=O)CCCc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L16 compound treatment 0.8662 -0.00211 -0.02 0.8146 -0.0573 -0.86 -0.6266 -0.7272 3069741 BPBio1_000962 CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CCC4=O)[C@@H]3CC=C2C1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L17 compound treatment 0.8263 -0.0419 -0.49 0.8123 -0.0596 -0.9 -0.9817 -0.9602 1215118 BPBio1_000963 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4COc5ccccc5O4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L18 compound treatment 0.8467 -0.0216 -0.25 0.8376 -0.0343 -0.52 -0.5437 -0.9463 1095 BPBio1_000964 NC(CO)C(=O)NNCc1ccc(O)c(O)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L19 compound treatment 0.829 -0.0393 -0.46 0.8622 -0.00967 -0.15 -0.4287 -0.8872 3616839 BPBio1_000965 CC(C)n1c(/C=C/[C@H](O)C[C@H](O)CC(=O)O)c(c2ccc(F)cc2)c3ccccc13 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L20 compound treatment 0.8638 -0.00447 -0.05 0.8569 -0.0149 -0.22 -0.1961 -0.8493 2685 BPBio1_000966 OC(=O)c1c(I)cc(I)c(NC(=O)CCCCC(=O)Nc2c(I)cc(I)c(C(=O)O)c2I)c1I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L21 compound treatment 0.8353 -0.033 -0.39 0.8415 -0.0304 -0.46 -0.5968 -0.9966 3069699 BPBio1_000967 C[C@@H]1NC(=O)NC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L22 compound treatment 0.9117 0.0434 0.51 0.9586 0.0868 1.3 1.2827 0.9158 1020463 BPBio1_000968 Oc1cc2ccc(=O)oc2cc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L23 mock treatment 0.8527 -0.0156 -0.18 0.872 1.88E-4 0.0 -0.1277 -0.6961 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 L24 mock treatment 0.8766 0.00828 0.1 0.8776 0.00576 0.09 0.13 0.9983 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M01 compound treatment 0.9984 0.13 1.53 0.9629 0.091 1.37 2.0475 0.9985 1677 BPBio1_000969 CC(C)c1cccc(C(C)C)c1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M02 compound treatment 0.9714 0.103 1.21 0.9085 0.0367 0.55 1.2453 0.9366 907141 BPBio1_000970 NCC(CP(=O)(O)O)c1ccc(Cl)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M03 compound treatment 0.9347 0.0664 0.78 0.9112 0.0393 0.59 0.9691 0.9908 1005 BPBio1_000971 OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M04 compound treatment 0.8079 -0.0604 -0.71 0.849 -0.0229 -0.34 -0.744 -0.9449 3069627 BPBio1_000972 CCC(=O)OC1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M05 compound treatment 0.9228 0.0545 0.64 0.8947 0.0229 0.34 0.6956 0.9577 1603 BPBio1_000973 OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M06 compound treatment 0.9371 0.0688 0.81 0.9325 0.0606 0.91 1.216 0.9982 1001531 BPBio1_000974 COc1cc(cc(OC)c1OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](O)c4cc5OCOc5cc24 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M07 compound treatment 0.9097 0.0414 0.49 0.8616 -0.0102 -0.15 0.2347 0.4607 907320 BPBio1_000975 CC(C)c1c(CN(C)C(C)Cc2ccccc2)n(C)n(c3ccccc3)c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M08 compound treatment 0.9205 0.0522 0.61 0.8666 -0.00527 -0.08 0.377 0.6106 877 BPBio1_000976 CC(C)(Oc1ccc(Cl)cc1)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M09 compound treatment 0.932 0.0637 0.75 0.8424 -0.0294 -0.44 0.2156 0.2481 955 BPBio1_000977 CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M10 compound treatment 0.8916 0.0234 0.27 0.8204 -0.0514 -0.77 -0.3529 -0.4301 917 BPBio1_000978 NS(=O)(=O)c1cc2c(NC(Cc3ccccc3)NS2(=O)=O)cc1C(F)(F)F 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M11 compound treatment 1.5519 0.684 8.02 0.8758 0.00397 0.06 5.7157 0.7123 1286 BPBio1_000979 Cc1cc(ccc1OCCOCC[N+](C)(C)Cc2ccccc2)C(C)(C)CC(C)(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M12 compound treatment 0.8893 0.0211 0.25 0.7964 -0.0754 -1.13 -0.6273 -0.5403 1481 BPBio1_000980 Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc4ccccc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M13 compound treatment 0.8486 -0.0197 -0.23 0.796 -0.0758 -1.14 -0.9702 -0.8336 863 BPBio1_000981 CN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M14 compound treatment 0.8954 0.0271 0.32 0.7888 -0.0831 -1.25 -0.6584 -0.5106 3092 BPBio1_000982 Cn1ccnc1S 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M15 compound treatment 0.8656 -0.00267 -0.03 0.7881 -0.0838 -1.26 -0.9133 -0.7245 1441 BPBio1_000983 CN1CCC(CC1)OC(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M16 compound treatment 0.9223 0.054 0.63 0.8198 -0.0521 -0.78 -0.105 -0.1042 3616821 BPBio1_000984 O[Hg]c1c(O)c(Br)cc2c1Oc3cc(O)c(Br)cc3C42OC(=O)c5ccccc54 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M17 compound treatment 0.9117 0.0434 0.51 0.8305 -0.0414 -0.62 -0.0802 -0.0998 1373 BPBio1_000985 CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M18 compound treatment 0.8328 -0.0355 -0.42 0.8376 -0.0343 -0.52 -0.6593 -0.9945 3187761 BPBio1_000986 CC(CNC1CCCCC1)OC(=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M19 compound treatment 0.7866 -0.0817 -0.96 0.8115 -0.0604 -0.91 -1.3201 -0.9996 1012 BPBio1_000987 Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M20 compound treatment 0.8512 -0.0171 -0.2 0.8524 -0.0195 -0.29 -0.3486 -0.9828 793 BPBio1_000988 CCN(CC)CCOC(=O)C(C1CCCCC1)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M21 compound treatment 0.9849 0.117 1.37 1.0174 0.145 2.19 2.5147 0.9744 2117332 BPBio1_000989 C[C@@]12CC[C@H]3[C@@H](CC[C@]4(O)C[C@@H](O)CC[C@]34C=O)[C@@]2(O)CC[C@@H]1C5=CC(=O)OC5 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M22 compound treatment 0.9751 0.107 1.25 1.0055 0.134 2.01 2.3078 0.9741 2080598 BPBio1_000990 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@H](O)CC2CC(=O)NC(=O)C2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M23 mock treatment 0.8581 -0.0102 -0.12 0.857 -0.0148 -0.22 -0.2425 -0.9576 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 M24 mock treatment 0.8869 0.0186 0.22 0.865 -0.00684 -0.1 0.0815 0.3378 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N01 compound treatment 0.9809 0.113 1.32 0.9405 0.0686 1.03 1.664 0.9925 1001950 BPBio1_000991 COc1ccc2[C@@H](OC(=O)c2c1OC)[C@H]3N(C)CCc4cc5OCOc5cc34 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N02 compound treatment 0.9802 0.112 1.31 0.946 0.0741 1.11 1.717 0.9967 3614723 BPBio1_000992 Nn1cc(Br)c(=O)[nH]c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N03 compound treatment 0.996 0.128 1.5 0.9261 0.0543 0.82 1.6368 0.9592 1764 BPBio1_000993 NCC1(CC(=O)O)CCCCC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N04 compound treatment 0.9501 0.0818 0.96 0.9036 0.0318 0.48 1.0168 0.9481 2030 BPBio1_000994 OC(=O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N05 compound treatment 0.8702 0.00192 0.02 0.8451 -0.0268 -0.4 -0.2687 -0.6665 1694 BPBio1_000995 Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N06 compound treatment 0.9318 0.0635 0.75 0.8735 0.00162 0.02 0.5444 0.7299 907192 BPBio1_000996 CC[N+](C)(C)Cc1ccccc1Br 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N07 compound treatment 0.903 0.0348 0.41 0.8982 0.0264 0.4 0.569 0.9999 2764 BPBio1_000997 CC(O)(P(=O)(O)O)P(=O)(O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N08 compound treatment 0.9383 0.07 0.82 0.8548 -0.0171 -0.26 0.399 0.4636 3172714 BPBio1_000998 C[n+]1ccccc1/C=N/O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N09 compound treatment 0.9343 0.066 0.77 0.8812 0.00931 0.14 0.6466 0.8216 3069699 BPBio1_000999 C[C@@H]1NC(=O)NC1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N10 compound treatment 0.9222 0.0539 0.63 0.8108 -0.061 -0.92 -0.2018 -0.1811 1395 BPBio1_001000 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N11 compound treatment 0.9193 0.0511 0.6 0.8267 -0.0451 -0.68 -0.0562 -0.0621 1000094 BPBio1_001001 CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N12 compound treatment 0.9187 0.0504 0.59 0.7986 -0.0732 -1.1 -0.3606 -0.2884 3480629 BPBio1_001002 OCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N13 compound treatment 0.961 0.0927 1.09 0.8384 -0.0335 -0.5 0.4131 0.3445 3616840 BPBio1_001003 Nc1ncn(C2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N14 compound treatment 0.8474 -0.0208 -0.24 0.7461 -0.126 -1.89 -1.5107 -0.7919 1371 BPBio1_001004 CN(C)c1nc(nc(n1)N(C)C)N(C)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N15 compound treatment 0.862 -0.00628 -0.07 0.77 -0.102 -1.53 -1.1351 -0.7403 3616841 BPBio1_001005 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N16 compound treatment 0.9064 0.0381 0.45 0.8031 -0.0687 -1.03 -0.4146 -0.3681 349 BPBio1_001006 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N17 compound treatment 0.8213 -0.047 -0.55 0.7883 -0.0835 -1.26 -1.2783 -0.9318 1267 BPBio1_001007 CC(=O)Nc1ccc(O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N18 compound treatment 0.8435 -0.0248 -0.29 0.8301 -0.0417 -0.63 -0.6499 -0.939 1428570 BPBio1_001008 CC(C)(C)NC[C@H](O)COc1nsnc1N2CCOCC2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N19 compound treatment 0.85 -0.0183 -0.21 0.8386 -0.0333 -0.5 -0.5059 -0.9286 1604 BPBio1_001009 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N20 compound treatment 0.8395 -0.0287 -0.34 0.8361 -0.0357 -0.54 -0.6186 -0.9748 893 BPBio1_001010 NCC(O)c1ccc(O)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N21 compound treatment 0.9249 0.0566 0.66 0.9336 0.0617 0.93 1.126 0.9866 2137 BPBio1_001011 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N22 compound treatment 0.8505 -0.0178 -0.21 0.8555 -0.0164 -0.25 -0.322 -0.9965 806 BPBio1_001012 OC(=O)C1CCCNC1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N23 mock treatment 0.8754 0.00707 0.08 0.8634 -0.00845 -0.13 -0.0311 -0.2053 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 N24 mock treatment 0.888 0.0198 0.23 0.8703 -0.00154 -0.02 0.1476 0.6333 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O01 compound treatment 1.0022 0.134 1.57 0.9452 0.0733 1.1 1.891 0.9849 3060125 BPBio1_001013 CCc1c(ncc2[nH]c3cc(OC)c(OC)cc3c12)C(=O)OC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O02 compound treatment 0.9808 0.113 1.32 0.9304 0.0585 0.88 1.5559 0.9805 2292 BPBio1_001014 CP(=O)(O)CCCN 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O03 compound treatment 0.9615 0.0933 1.09 0.905 0.0331 0.5 1.1261 0.9364 1155 BPBio1_001015 Nc1ccc(cc1)S(=O)(=O)NC(=O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O04 compound treatment 0.9859 0.118 1.38 0.8748 0.00294 0.04 1.0077 0.7294 1000165 BPBio1_001016 COc1ccc2cc(ccc2c1)[C@@H](C)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O05 compound treatment 0.936 0.0677 0.79 0.8678 -0.0041 -0.06 0.5183 0.6503 1513 BPBio1_001017 CCOC(=O)c1ccc(N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O06 compound treatment 0.9607 0.0924 1.08 0.8922 0.0203 0.31 0.9832 0.8726 244 BPBio1_001018 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O07 compound treatment 0.9162 0.0479 0.56 0.8769 0.00507 0.08 0.4515 0.7957 1242 BPBio1_001019 CN(CS(=O)(=O)O)c1c(C)n(C)n(c2ccccc2)c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O08 compound treatment 0.9704 0.102 1.2 0.8871 0.0153 0.23 1.0096 0.8275 1431 BPBio1_001020 Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O09 compound treatment 0.9464 0.0781 0.92 0.8747 0.00285 0.04 0.6788 0.7393 1064 BPBio1_001021 [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@H](CO[C@H]12)O[N+](=O)[O-] 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O10 compound treatment 0.9383 0.0701 0.82 0.8616 -0.0102 -0.15 0.4727 0.5651 3187762 BPBio1_001022 CC1CC(CC(C)(C)N1C)OC(=O)C(O)c2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O11 compound treatment 0.9205 0.0522 0.61 0.8583 -0.0136 -0.2 0.289 0.4474 1668673 BPBio1_001023 Nc1ccc(cc1)S(=O)(=O)Nc2ccc(Cl)nn2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O12 compound treatment 0.9268 0.0585 0.69 0.8281 -0.0437 -0.66 0.0201 0.0212 3383 BPBio1_001024 Cc1cc(no1)C(=O)NNCc2ccccc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O13 compound treatment 0.9598 0.0915 1.07 0.8041 -0.0678 -1.02 0.0384 0.026 1467 BPBio1_001025 CCCCOc1ccc(OCCCN2CCOCC2)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O14 compound treatment 0.9601 0.0918 1.08 0.8288 -0.0431 -0.65 0.3039 0.2417 2105063 BPBio1_001026 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O15 compound treatment 0.9604 0.0921 1.08 0.8109 -0.061 -0.92 0.1161 0.0819 3069574 BPBio1_001027 CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O16 compound treatment 0.9392 0.0709 0.83 0.8419 -0.0299 -0.45 0.2704 0.2856 2752 BPBio1_001028 COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O17 compound treatment 0.8024 -0.0659 -0.77 0.7989 -0.073 -1.1 -1.3228 -0.9853 2081008 BPBio1_001029 C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)C)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O18 compound treatment 0.8604 -0.00785 -0.09 0.8731 0.00123 0.02 -0.0521 -0.5545 1370 BPBio1_001030 C/C=C(/C(=C/C)/c1ccc(O)cc1)\c2ccc(O)cc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O19 compound treatment 0.8441 -0.0242 -0.28 0.825 -0.0469 -0.71 -0.6992 -0.9199 759 BPBio1_001031 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O20 compound treatment 0.8637 -0.0046 -0.05 0.8486 -0.0233 -0.35 -0.286 -0.8064 1328 BPBio1_001032 OC(CCN1CCCCC1)(c2ccccc2)c3ccccc3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O21 compound treatment 0.8715 0.00318 0.04 0.857 -0.0149 -0.22 -0.1316 -0.5809 3616807 BPBio1_001033 CO/N=C(\C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)N)/c3ccco3 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O22 compound treatment 0.8714 0.00317 0.04 0.8376 -0.0342 -0.51 -0.3376 -0.6543 794 BPBio1_001034 Nc1cc(c[nH]c1=O)c2ccncc2 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O23 mock treatment 0.8584 -0.00986 -0.12 0.8591 -0.0128 -0.19 -0.218 -0.9704 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 O24 mock treatment 0.8889 0.0206 0.24 0.8964 0.0246 0.37 0.4323 0.9791 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P01 compound treatment 0.9727 0.104 1.23 0.9606 0.0887 1.33 1.8105 0.9991 1206 BPBio1_001035 CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P02 compound treatment 0.9863 0.118 1.39 0.9416 0.0698 1.05 1.7217 0.9906 3060051 BPBio1_001036 COC(=O)c1cc2c(cn1)[nH]c3ccccc32 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P03 compound treatment 0.9622 0.094 1.1 0.932 0.0601 0.9 1.4188 0.9951 3069701 BPBio1_001037 C[C@H](O)C(=O)Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P04 compound treatment 0.9288 0.0605 0.71 0.9011 0.0293 0.44 0.8134 0.9736 2660 BPBio1_001038 CCN(C(=O)/C=C/C)c1ccccc1C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P05 compound treatment 0.9789 0.111 1.3 0.9263 0.0544 0.82 1.4973 0.9752 3487261 BPBio1_001039 COCC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P06 compound treatment 0.9689 0.101 1.18 0.8914 0.0195 0.29 1.0427 0.8566 351 BPBio1_001040 CC(C)NCC(O)COc1cccc2ccccc12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P07 compound treatment 0.9405 0.0722 0.85 0.9173 0.0454 0.68 1.0823 0.9943 856 BPBio1_001041 Cn1c(=O)n(C)c2nc[nH]c2c1=O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P08 compound treatment 0.9584 0.0902 1.06 0.902 0.0301 0.45 1.0684 0.9283 1001858 BPBio1_001042 CC(C)NC[C@H](O)COc1ccc(CC(=O)N)cc1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P09 compound treatment 0.9305 0.0623 0.73 0.8807 0.00885 0.13 0.6108 0.8223 1222 BPBio1_001043 Cn1cnc2n(C)c(=O)[nH]c(=O)c12 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P10 compound treatment 0.9617 0.0934 1.1 0.8777 0.00589 0.09 0.8376 0.7617 3188022 BPBio1_001044 CC(C)(C)CC(C)(C)c1ccc(OCOCCOCCO)c(Cc2cc(cc(Cc3cc(ccc3OCOCCOCCO)C(C)(C)CC(C)(C)C)c2OCOCCOCCO)C(C)(C)CC(C)(C)C)c1 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P11 compound treatment 0.9499 0.0816 0.96 0.9057 0.0338 0.51 1.0371 0.956 687 BPBio1_001045 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P12 compound treatment 0.9165 0.0482 0.57 0.8854 0.0135 0.2 0.544 0.9045 3069742 BPBio1_001046 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P13 compound treatment 0.9801 0.112 1.31 0.8641 -0.00776 -0.12 0.8456 0.6417 989 BPBio1_001047 NC(=N)NCCCCNC(=N)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P14 compound treatment 0.9825 0.114 1.34 0.8265 -0.0453 -0.68 0.4657 0.3097 4369 BPBio1_001048 CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C)C(=O)C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P15 compound treatment 1.0121 0.144 1.69 0.8961 0.0243 0.36 1.4515 0.8405 3075421 BPBio1_001049 CN1[C@H]2C[C@@H](C[C@@H]1[C@H]3O[C@H]32)OC(=O)[C@H](CO)c4ccccc4 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P16 compound treatment 0.9518 0.0835 0.98 0.8572 -0.0147 -0.22 0.5372 0.5345 3069771 BPBio1_001050 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P17 compound treatment 0.9313 0.063 0.74 0.8854 0.0136 0.2 0.6672 0.8697 3487262 BPBio1_001051 OCCN(C(=O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P18 compound treatment 0.8947 0.0265 0.31 0.8765 0.00463 0.07 0.2688 0.8447 1000212 BPBio1_001052 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P19 compound treatment 1.0485 0.18 2.11 0.9167 0.0448 0.67 1.9716 0.8884 446 BPBio1_001053 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P20 compound treatment 0.9238 0.0555 0.65 0.8342 -0.0376 -0.57 0.0606 0.0701 4481 BPBio1_001054 CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P21 compound treatment 0.9043 0.036 0.42 0.8613 -0.0106 -0.16 0.1862 0.4121 1327 BPBio1_001055 C[N+](C)(C)CCOC(=O)N 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P22 compound treatment 0.9089 0.0406 0.48 0.8385 -0.0334 -0.5 -0.0181 -0.0261 1167 BPBio1_001056 NCCCCCC(=O)O 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P23 mock treatment 0.8821 0.0138 0.16 0.8771 0.0052 0.08 0.1698 0.9442 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.2322 P24 mock treatment 0.8369 -0.0314 -0.37 0.8775 0.00564 0.08 -0.2003 -0.5302 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A01 mock treatment 1.079 0.113 1.33 0.9232 0.0406 0.61 1.3698 0.9382 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A02 mock treatment 1.041 0.0749 0.88 0.9776 0.095 1.43 1.6322 0.9728 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A03 mock treatment 1.0015 0.0354 0.42 0.9384 0.0558 0.84 0.8878 0.9476 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A04 mock treatment 1.0124 0.0464 0.54 0.9322 0.0497 0.75 0.9134 0.9879 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A05 mock treatment 0.9899 0.0238 0.28 0.951 0.0684 1.03 0.9251 0.8677 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A06 mock treatment 0.9968 0.0307 0.36 0.9221 0.0395 0.59 0.6751 0.9713 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A07 mock treatment 0.985 0.0189 0.22 0.9278 0.0453 0.68 0.6383 0.8914 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A08 mock treatment 0.965 -0.00107 -0.01 0.9149 0.0323 0.49 0.3349 0.6886 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A09 mock treatment 0.9543 -0.0118 -0.14 0.7343 -0.148 -2.23 -1.6745 -0.7494 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A10 mock treatment 1.0152 0.0491 0.58 0.9268 0.0443 0.67 0.8781 0.9974 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A11 mock treatment 0.9842 0.0182 0.21 0.8715 -0.0111 -0.17 0.0332 0.1229 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A12 mock treatment 1.0152 0.0491 0.58 0.8719 -0.0107 -0.16 0.2943 0.4917 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A13 mock treatment 1.0259 0.0599 0.7 0.8749 -0.00767 -0.12 0.4154 0.5832 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A14 mock treatment 0.9716 0.00555 0.07 0.8931 0.0106 0.16 0.1584 0.9225 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A15 mock treatment 0.934 -0.0321 -0.38 0.8837 0.00114 0.02 -0.2541 -0.6743 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A16 mock treatment 0.9381 -0.028 -0.33 0.874 -0.00855 -0.13 -0.323 -0.9163 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A17 mock treatment 0.9322 -0.0339 -0.4 0.8913 0.00876 0.13 -0.1879 -0.4488 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A18 mock treatment 0.9312 -0.0348 -0.41 0.9017 0.0191 0.29 -0.0856 -0.1711 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A19 mock treatment 0.9061 -0.06 -0.7 0.8751 -0.00749 -0.11 -0.5775 -0.8099 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A20 mock treatment 0.8759 -0.0902 -1.06 0.8635 -0.0191 -0.29 -0.9514 -0.8675 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A21 mock treatment 0.9139 -0.0521 -0.61 0.8372 -0.0453 -0.68 -0.9142 -0.9986 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A22 mock treatment 0.9323 -0.0338 -0.4 0.8554 -0.0272 -0.41 -0.5691 -0.9999 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A23 mock treatment 0.9611 -0.00497 -0.06 0.8422 -0.0403 -0.61 -0.47 -0.7716 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base A24 mock treatment 0.9561 -0.00995 -0.12 0.8698 -0.0127 -0.19 -0.2176 -0.9721 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B01 mock treatment 1.0468 0.0807 0.95 0.9662 0.0837 1.26 1.5596 0.9902 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B02 mock treatment 1.0165 0.0504 0.59 0.9648 0.0823 1.24 1.2935 0.9429 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B03 mock treatment 0.9845 0.0184 0.22 0.9692 0.0867 1.3 1.0742 0.8132 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B04 mock treatment 0.9853 0.0192 0.23 0.9352 0.0527 0.79 0.7197 0.8736 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B05 mock treatment 0.9704 0.0043 0.05 0.9302 0.0476 0.72 0.542 0.7551 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B06 mock treatment 0.9862 0.0202 0.24 0.9211 0.0386 0.58 0.5779 0.9218 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B07 mock treatment 0.9651 -9.97E-4 -0.01 0.9364 0.0539 0.81 0.5646 0.6968 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B08 mock treatment 0.9733 0.00722 0.08 0.905 0.0224 0.34 0.2983 0.858 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B09 mock treatment 0.9472 -0.0189 -0.22 0.9414 0.0589 0.89 0.4694 0.5141 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B10 mock treatment 0.9671 0.00109 0.01 0.913 0.0304 0.46 0.3327 0.7266 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B11 mock treatment 0.9468 -0.0193 -0.23 0.878 -0.00454 -0.07 -0.2082 -0.8812 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B12 mock treatment 0.9545 -0.0116 -0.14 0.8681 -0.0144 -0.22 -0.2493 -0.9746 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B13 mock treatment 0.9752 0.00912 0.11 0.8755 -0.00703 -0.11 0.001 0.0065 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B14 mock treatment 0.9433 -0.0227 -0.27 0.8498 -0.0327 -0.49 -0.537 -0.9586 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B15 mock treatment 0.9217 -0.0444 -0.52 0.8518 -0.0308 -0.46 -0.6956 -0.9983 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B16 mock treatment 0.9079 -0.0582 -0.68 0.8948 0.0122 0.18 -0.3525 -0.4986 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B17 mock treatment 0.8716 -0.0944 -1.11 0.8639 -0.0186 -0.28 -0.9817 -0.8589 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B18 mock treatment 0.9008 -0.0652 -0.77 0.8736 -0.00897 -0.13 -0.6368 -0.8191 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B19 mock treatment 0.8825 -0.0836 -0.98 0.8645 -0.018 -0.27 -0.8855 -0.8699 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B20 mock treatment 0.9027 -0.0633 -0.74 0.8651 -0.0174 -0.26 -0.7107 -0.9019 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B21 mock treatment 0.8882 -0.0778 -0.91 0.8683 -0.0142 -0.21 -0.7973 -0.8498 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B22 mock treatment 0.862 -0.104 -1.22 0.8714 -0.0111 -0.17 -0.982 -0.7964 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B23 mock treatment 0.9042 -0.0619 -0.73 0.8717 -0.0108 -0.16 -0.6284 -0.8444 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base B24 mock treatment 0.928 -0.0381 -0.45 0.8969 0.0143 0.22 -0.1634 -0.3295 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C01 mock treatment 1.0308 0.0647 0.76 0.9336 0.051 0.77 1.0801 1.0 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C02 mock treatment 1.0341 0.0681 0.8 0.948 0.0655 0.98 1.2614 0.9946 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C03 mock treatment 1.0279 0.0618 0.73 0.9159 0.0334 0.5 0.8678 0.9838 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C04 mock treatment 0.9904 0.0243 0.29 0.9178 0.0353 0.53 0.5772 0.9577 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C05 mock treatment 0.9841 0.018 0.21 0.8997 0.0172 0.26 0.3323 0.9951 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C06 mock treatment 0.9973 0.0312 0.37 0.9351 0.0526 0.79 0.818 0.9389 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C07 mock treatment 0.9496 -0.0165 -0.19 0.9288 0.0463 0.7 0.3557 0.4922 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C08 mock treatment 0.9459 -0.0202 -0.24 0.9013 0.0188 0.28 0.0321 0.0871 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C09 mock treatment 0.9154 -0.0506 -0.59 0.8751 -0.00749 -0.11 -0.4999 -0.8263 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C10 mock treatment 0.9615 -0.00454 -0.05 0.8744 -0.00818 -0.12 -0.1247 -0.9301 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C11 mock treatment 0.9441 -0.022 -0.26 0.8713 -0.0112 -0.17 -0.3017 -0.9787 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C12 mock treatment 0.9846 0.0186 0.22 0.8722 -0.0103 -0.16 0.0442 0.1649 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C13 mock treatment 0.9742 0.0081 0.1 0.8257 -0.0568 -0.85 -0.537 -0.6246 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C14 mock treatment 0.9391 -0.027 -0.32 0.8497 -0.0329 -0.49 -0.5734 -0.9769 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C15 mock treatment 0.9426 -0.0234 -0.27 0.9 0.0175 0.26 -0.0084 -0.022 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C16 mock treatment 0.9294 -0.0366 -0.43 0.8628 -0.0197 -0.3 -0.5137 -0.9836 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C17 mock treatment 0.9304 -0.0356 -0.42 0.8926 0.0101 0.15 -0.1888 -0.4246 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C18 mock treatment 0.8793 -0.0868 -1.02 0.8675 -0.015 -0.23 -0.8798 -0.8435 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C19 mock treatment 0.9107 -0.0554 -0.65 0.8554 -0.0272 -0.41 -0.7488 -0.975 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C20 mock treatment 0.879 -0.087 -1.02 0.811 -0.0715 -1.08 -1.4825 -0.9997 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C21 mock treatment 0.9098 -0.0562 -0.66 0.8802 -0.00232 -0.03 -0.4913 -0.7434 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C22 mock treatment 0.878 -0.0881 -1.03 0.8745 -0.00807 -0.12 -0.8168 -0.7847 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C23 mock treatment 0.8629 -0.103 -1.21 0.8745 -0.00807 -0.12 -0.9421 -0.7741 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base C24 mock treatment 0.9705 0.00443 0.05 0.8834 8.83E-4 0.01 0.0461 0.8602 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D01 mock treatment 1.0371 0.071 0.83 0.9502 0.0677 1.02 1.3088 0.9951 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D02 mock treatment 1.0148 0.0487 0.57 0.9164 0.0339 0.51 0.7646 0.9983 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D03 mock treatment 0.9903 0.0242 0.28 0.9218 0.0393 0.59 0.6189 0.9439 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D04 mock treatment 1.0133 0.0472 0.55 0.9084 0.0259 0.39 0.667 0.9851 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D05 mock treatment 0.9707 0.00462 0.05 0.8757 -0.00684 -0.1 -0.0343 -0.2954 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D06 mock treatment 0.9906 0.0246 0.29 0.8905 0.00792 0.12 0.288 0.9235 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D07 mock treatment 0.9722 0.00618 0.07 0.8981 0.0155 0.23 0.2163 0.8852 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D08 mock treatment 0.9455 -0.0205 -0.24 0.8999 0.0174 0.26 0.0144 0.0404 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D09 mock treatment 0.9787 0.0127 0.15 0.9056 0.023 0.35 0.3499 0.9289 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D10 mock treatment 0.9662 1.49E-4 0.0 0.8967 0.0141 0.21 0.1516 0.7129 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D11 mock treatment 0.9757 0.00961 0.11 0.8647 -0.0178 -0.27 -0.1096 -0.3772 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D12 mock treatment 0.9871 0.021 0.25 0.8225 -0.06 -0.9 -0.4636 -0.4954 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D13 mock treatment 0.992 0.0259 0.3 0.8423 -0.0403 -0.61 -0.2133 -0.3147 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D14 mock treatment 0.9487 -0.0174 -0.2 0.8487 -0.0338 -0.51 -0.5038 -0.9198 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D15 mock treatment 0.8901 -0.076 -0.89 0.878 -0.00456 -0.07 -0.6791 -0.7592 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D16 mock treatment 0.9176 -0.0484 -0.57 0.8591 -0.0234 -0.35 -0.6509 -0.9734 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D17 mock treatment 0.8627 -0.103 -1.21 0.8763 -0.00623 -0.09 -0.9238 -0.7595 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D18 mock treatment 0.8887 -0.0773 -0.91 0.8784 -0.00418 -0.06 -0.6864 -0.7543 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D19 mock treatment 0.9105 -0.0556 -0.65 0.829 -0.0536 -0.81 -1.0308 -0.9945 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D20 mock treatment 0.8978 -0.0683 -0.8 0.8605 -0.022 -0.33 -0.801 -0.9235 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D21 mock treatment 0.8983 -0.0678 -0.8 0.8513 -0.0313 -0.47 -0.8948 -0.9686 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D22 mock treatment 0.8897 -0.0763 -0.9 0.8796 -0.00293 -0.04 -0.6645 -0.741 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D23 mock treatment 0.8914 -0.0746 -0.88 0.8716 -0.0109 -0.16 -0.7355 -0.8255 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base D24 mock treatment 0.9808 0.0147 0.17 0.8488 -0.0337 -0.51 -0.2365 -0.4416 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E01 mock treatment 1.0068 0.0407 0.48 0.9557 0.0732 1.1 1.1159 0.9303 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E02 mock treatment 0.9892 0.0232 0.27 0.9136 0.031 0.47 0.5222 0.9669 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E03 mock treatment 0.9894 0.0234 0.27 0.9595 0.077 1.16 1.0128 0.8511 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E04 mock treatment 1.0241 0.0581 0.68 0.894 0.0115 0.17 0.6039 0.859 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E05 mock treatment 0.9939 0.0278 0.33 0.9389 0.0563 0.85 0.8298 0.9141 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E06 mock treatment 0.9382 -0.0279 -0.33 0.9012 0.0186 0.28 -0.0331 -0.0769 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E07 mock treatment 0.969 0.00299 0.04 0.8751 -0.00746 -0.11 -0.0545 -0.4638 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E08 mock treatment 0.9691 0.00305 0.04 0.923 0.0405 0.61 0.4559 0.7474 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E09 mock treatment 0.9538 -0.0122 -0.14 0.8933 0.0107 0.16 0.0126 0.0582 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E10 mock treatment 0.9447 -0.0214 -0.25 0.8726 -0.00998 -0.15 -0.2837 -0.9698 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E11 mock treatment 0.9516 -0.0145 -0.17 0.8491 -0.0334 -0.5 -0.4754 -0.8966 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E12 mock treatment 0.9943 0.0283 0.33 0.8917 0.00919 0.14 0.3324 0.9246 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E13 mock treatment 0.9644 -0.00167 -0.02 0.8437 -0.0389 -0.58 -0.4272 -0.7303 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E14 mock treatment 0.961 -0.00502 -0.06 0.8859 0.00338 0.05 -0.0057 -0.0733 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E15 mock treatment 0.9231 -0.0429 -0.5 0.8412 -0.0413 -0.62 -0.796 -0.9945 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E16 mock treatment 0.9063 -0.0597 -0.7 0.8569 -0.0256 -0.38 -0.768 -0.9602 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E17 mock treatment 0.9117 -0.0544 -0.64 0.861 -0.0215 -0.32 -0.6801 -0.9503 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E18 mock treatment 0.9141 -0.0519 -0.61 0.8459 -0.0367 -0.55 -0.8208 -0.9988 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E19 mock treatment 0.8928 -0.0733 -0.86 0.8713 -0.0112 -0.17 -0.7277 -0.8302 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E20 mock treatment 0.8833 -0.0827 -0.97 0.8441 -0.0384 -0.58 -1.0951 -0.9693 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E21 mock treatment 0.8947 -0.0714 -0.84 0.8909 0.00838 0.13 -0.5033 -0.5941 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E22 mock treatment 0.8838 -0.0823 -0.97 0.884 0.00142 0.02 -0.668 -0.6913 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E23 mock treatment 0.9192 -0.0469 -0.55 0.8948 0.0123 0.18 -0.2583 -0.4454 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base E24 mock treatment 0.9728 0.00678 0.08 0.8881 0.00551 0.08 0.1149 0.9998 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F01 mock treatment 1.0156 0.0496 0.58 0.9607 0.0781 1.18 1.2423 0.9474 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F02 mock treatment 1.0277 0.0616 0.72 0.9428 0.0602 0.91 1.1518 0.9938 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F03 mock treatment 0.9921 0.0261 0.31 0.8928 0.0103 0.15 0.3258 0.9502 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F04 mock treatment 1.0074 0.0413 0.48 0.8879 0.00533 0.08 0.3994 0.8129 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F05 mock treatment 1.0026 0.0365 0.43 0.9051 0.0226 0.34 0.5431 0.9933 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F06 mock treatment 0.9952 0.0291 0.34 0.845 -0.0375 -0.56 -0.1572 -0.2382 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F07 mock treatment 0.9784 0.0124 0.15 0.9212 0.0387 0.58 0.5139 0.8575 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F08 mock treatment 0.9968 0.0307 0.36 0.857 -0.0255 -0.38 -0.0168 -0.0319 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F09 mock treatment 0.9785 0.0125 0.15 0.9236 0.0411 0.62 0.5406 0.851 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F10 mock treatment 0.9567 -0.00936 -0.11 0.851 -0.0316 -0.47 -0.4132 -0.8483 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F11 mock treatment 0.9496 -0.0164 -0.19 0.8937 0.0112 0.17 -0.0172 -0.0672 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F12 mock treatment 0.9901 0.0241 0.28 0.869 -0.0135 -0.2 0.0562 0.1613 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F13 mock treatment 0.9756 0.00958 0.11 0.8648 -0.0178 -0.27 -0.1096 -0.3778 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F14 mock treatment 0.9876 0.0216 0.25 0.8719 -0.0107 -0.16 0.0653 0.2179 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F15 mock treatment 0.9252 -0.0409 -0.48 0.8384 -0.0442 -0.66 -0.8087 -0.9873 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F16 mock treatment 0.9348 -0.0312 -0.37 0.8254 -0.0572 -0.86 -0.8668 -0.9277 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F17 mock treatment 0.9081 -0.058 -0.68 0.8385 -0.0441 -0.66 -0.9497 -0.9999 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F18 mock treatment 0.8929 -0.0732 -0.86 0.8539 -0.0286 -0.43 -0.9115 -0.9489 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F19 mock treatment 0.9083 -0.0577 -0.68 0.8606 -0.022 -0.33 -0.713 -0.9456 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F20 mock treatment 0.9042 -0.0618 -0.73 0.8494 -0.0332 -0.5 -0.8659 -0.9832 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F21 mock treatment 0.9105 -0.0556 -0.65 0.8334 -0.0491 -0.74 -0.9836 -0.9981 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F22 mock treatment 0.8968 -0.0692 -0.81 0.8823 -2.68E-4 0.0 -0.5773 -0.7106 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F23 mock treatment 0.9366 -0.0295 -0.35 0.8801 -0.00248 -0.04 -0.2708 -0.779 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base F24 mock treatment 0.9622 -0.00391 -0.05 0.8904 0.00789 0.12 0.0515 0.4047 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G01 mock treatment 1.0402 0.0742 0.87 0.9444 0.0619 0.93 1.2733 0.9995 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G02 mock treatment 1.0407 0.0746 0.88 0.8953 0.0128 0.19 0.7553 0.8422 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G03 mock treatment 1.0007 0.0346 0.41 0.9001 0.0176 0.26 0.4743 0.9783 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G04 mock treatment 1.0102 0.0442 0.52 0.8757 -0.00684 -0.1 0.2939 0.556 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G05 mock treatment 1.0272 0.0612 0.72 0.8946 0.012 0.18 0.6357 0.8587 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G06 mock treatment 0.9932 0.0271 0.32 0.9096 0.027 0.41 0.5125 0.9927 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G07 mock treatment 0.9594 -0.00669 -0.08 0.8915 0.00894 0.13 0.0396 0.2542 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G08 mock treatment 0.964 -0.00209 -0.02 0.9016 0.019 0.29 0.185 0.6441 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G09 mock treatment 0.9691 0.00306 0.04 0.8909 0.00832 0.13 0.1139 0.8749 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G10 mock treatment 1.0105 0.0445 0.52 0.894 0.0114 0.17 0.4906 0.8926 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G11 mock treatment 0.9799 0.0139 0.16 0.891 0.00842 0.13 0.2045 0.9923 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G12 mock treatment 0.9787 0.0126 0.15 0.8495 -0.0331 -0.5 -0.2468 -0.4759 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G13 mock treatment 0.9624 -0.00366 -0.04 0.8417 -0.0409 -0.61 -0.465 -0.7546 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G14 mock treatment 0.9481 -0.0179 -0.21 0.8575 -0.0251 -0.38 -0.4154 -0.9619 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G15 mock treatment 0.9359 -0.0302 -0.35 0.8691 -0.0134 -0.2 -0.3931 -0.9645 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G16 mock treatment 0.9143 -0.0517 -0.61 0.8484 -0.0342 -0.51 -0.7926 -0.9966 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G17 mock treatment 0.891 -0.0751 -0.88 0.8378 -0.0448 -0.67 -1.0994 -0.9912 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G18 mock treatment 0.9107 -0.0553 -0.65 0.8562 -0.0263 -0.4 -0.7392 -0.9719 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G19 mock treatment 0.8979 -0.0681 -0.8 0.8324 -0.0501 -0.75 -1.0985 -0.9996 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G20 mock treatment 0.9268 -0.0392 -0.46 0.8409 -0.0416 -0.63 -0.7683 -0.9885 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G21 mock treatment 0.8935 -0.0726 -0.85 0.8325 -0.05 -0.75 -1.1343 -0.9981 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G22 mock treatment 0.9074 -0.0586 -0.69 0.8623 -0.0202 -0.3 -0.7018 -0.9327 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G23 mock treatment 0.9253 -0.0408 -0.48 0.871 -0.0115 -0.17 -0.4605 -0.9054 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base G24 mock treatment 0.9487 -0.0174 -0.2 0.8672 -0.0154 -0.23 -0.3076 -0.998 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H01 mock treatment 1.0616 0.0956 1.12 0.9287 0.0461 0.69 1.2837 0.9733 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H02 mock treatment 1.071 0.105 1.23 0.8907 0.00817 0.12 0.9579 0.7738 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H03 mock treatment 1.0146 0.0485 0.57 0.9045 0.0219 0.33 0.6359 0.9662 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H04 mock treatment 1.018 0.0519 0.61 0.8891 0.00651 0.1 0.5003 0.8103 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H05 mock treatment 1.0245 0.0584 0.69 0.9196 0.0371 0.56 0.879 0.9947 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H06 mock treatment 1.0259 0.0599 0.7 0.9179 0.0353 0.53 0.8725 0.9905 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H07 mock treatment 1.012 0.046 0.54 0.8947 0.0121 0.18 0.5106 0.8962 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H08 mock treatment 0.9952 0.0292 0.34 0.903 0.0204 0.31 0.4593 0.9986 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H09 mock treatment 0.9847 0.0187 0.22 0.8691 -0.0134 -0.2 0.0126 0.0424 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H10 mock treatment 0.9962 0.0301 0.35 0.8919 0.00937 0.14 0.3496 0.9187 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H11 mock treatment 0.9838 0.0178 0.21 0.9026 0.02 0.3 0.3606 0.9839 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H12 mock treatment 0.9906 0.0246 0.29 0.8408 -0.0417 -0.63 -0.2396 -0.347 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H13 mock treatment 0.9694 0.00332 0.04 0.8465 -0.0361 -0.54 -0.3558 -0.6545 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H14 mock treatment 0.9867 0.0206 0.24 0.8377 -0.0448 -0.67 -0.3057 -0.4265 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H15 mock treatment 0.9188 -0.0473 -0.55 0.8704 -0.0122 -0.18 -0.5215 -0.8929 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H16 mock treatment 0.9457 -0.0203 -0.24 0.8951 0.0125 0.19 -0.0354 -0.1163 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H17 mock treatment 0.9269 -0.0392 -0.46 0.8658 -0.0167 -0.25 -0.5032 -0.9597 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H18 mock treatment 0.9102 -0.0559 -0.66 0.8159 -0.0667 -1.0 -1.1724 -0.9788 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H19 mock treatment 0.9246 -0.0415 -0.49 0.8533 -0.0293 -0.44 -0.6558 -0.9987 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H20 mock treatment 0.9049 -0.0612 -0.72 0.8486 -0.034 -0.51 -0.8693 -0.9861 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H21 mock treatment 0.9071 -0.0589 -0.69 0.7887 -0.0939 -1.41 -1.4875 -0.9461 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H22 mock treatment 0.9122 -0.0538 -0.63 0.8734 -0.0091 -0.14 -0.5436 -0.8408 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H23 mock treatment 0.928 -0.0381 -0.45 0.8938 0.0112 0.17 -0.1964 -0.4111 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base H24 mock treatment 0.9517 -0.0144 -0.17 0.8978 0.0152 0.23 0.0426 0.1499 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I01 mock treatment 1.0109 0.0449 0.53 0.9378 0.0552 0.83 0.9599 0.9759 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I02 mock treatment 1.048 0.0819 0.96 0.8973 0.0148 0.22 0.837 0.8483 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I03 mock treatment 0.9957 0.0296 0.35 0.9049 0.0223 0.34 0.4834 0.9998 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I04 mock treatment 1.0058 0.0397 0.47 0.9186 0.036 0.54 0.7127 0.9972 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I05 mock treatment 1.0079 0.0419 0.49 0.9528 0.0703 1.06 1.0946 0.9394 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I06 mock treatment 1.0278 0.0618 0.73 0.8925 0.00995 0.15 0.6185 0.8354 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I07 mock treatment 1.0006 0.0345 0.41 0.882 -5.25E-4 -0.01 0.2811 0.6932 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I08 mock treatment 0.9814 0.0153 0.18 0.9067 0.0241 0.36 0.384 0.9478 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I09 mock treatment 0.9788 0.0127 0.15 0.889 0.00642 0.1 0.1739 0.9777 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I10 mock treatment 0.9622 -0.00383 -0.04 0.8839 0.00136 0.02 -0.0173 -0.3505 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I11 mock treatment 0.9597 -0.0064 -0.08 0.8822 -2.96E-4 0.0 -0.0563 -0.7477 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I12 mock treatment 0.977 0.0109 0.13 0.8536 -0.029 -0.44 -0.2174 -0.4785 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I13 mock treatment 0.9588 -0.00726 -0.09 0.8324 -0.0501 -0.75 -0.5931 -0.7821 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I14 mock treatment 0.9531 -0.0129 -0.15 0.8732 -0.00939 -0.14 -0.207 -0.9994 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I15 mock treatment 0.9571 -0.009 -0.11 0.8894 0.00682 0.1 -0.0022 -0.0146 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I16 mock treatment 0.915 -0.0511 -0.6 0.8551 -0.0275 -0.41 -0.7161 -0.9834 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I17 mock treatment 0.907 -0.0591 -0.69 0.8529 -0.0296 -0.45 -0.8053 -0.9772 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I18 mock treatment 0.9147 -0.0514 -0.6 0.8433 -0.0392 -0.59 -0.8435 -0.9999 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I19 mock treatment 0.915 -0.051 -0.6 0.8691 -0.0135 -0.2 -0.5667 -0.8963 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I20 mock treatment 0.9007 -0.0653 -0.77 0.8366 -0.046 -0.69 -1.031 -0.9987 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I21 mock treatment 0.9232 -0.0429 -0.5 0.837 -0.0455 -0.68 -0.8399 -0.9886 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I22 mock treatment 0.8903 -0.0757 -0.89 0.8853 0.00275 0.04 -0.5994 -0.6735 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I23 mock treatment 0.9099 -0.0562 -0.66 0.8667 -0.0159 -0.24 -0.6349 -0.9054 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base I24 mock treatment 0.9572 -0.00886 -0.1 0.8933 0.0108 0.16 0.0411 0.2136 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J01 mock treatment 1.0639 0.0978 1.15 0.9641 0.0816 1.23 1.6794 0.9995 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J02 mock treatment 1.0582 0.0921 1.08 0.9439 0.0613 0.92 1.4164 0.9969 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J03 mock treatment 1.035 0.069 0.81 0.9266 0.044 0.66 1.0405 0.995 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J04 mock treatment 1.0437 0.0776 0.91 0.9313 0.0487 0.73 1.1624 0.9942 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J05 mock treatment 1.0129 0.0469 0.55 0.8984 0.0159 0.24 0.5575 0.93 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J06 mock treatment 1.0242 0.0581 0.68 0.8757 -0.00687 -0.1 0.4094 0.5933 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J07 mock treatment 1.016 0.0499 0.59 0.886 0.00343 0.05 0.451 0.7663 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J08 mock treatment 1.0084 0.0423 0.5 0.876 -0.0065 -0.1 0.2821 0.5573 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J09 mock treatment 1.0077 0.0416 0.49 0.8934 0.0109 0.16 0.461 0.895 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J10 mock treatment 0.9571 -0.00897 -0.11 0.9014 0.0188 0.28 0.1259 0.4166 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J11 mock treatment 0.9611 -0.00494 -0.06 0.8731 -0.00949 -0.14 -0.1419 -0.9213 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J12 mock treatment 0.9363 -0.0298 -0.35 0.8871 0.00461 0.07 -0.1979 -0.556 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J13 mock treatment 0.9675 0.00149 0.02 0.8674 -0.0151 -0.23 -0.1483 -0.6509 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J14 mock treatment 0.9609 -0.0052 -0.06 0.8691 -0.0134 -0.2 -0.186 -0.8813 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J15 mock treatment 0.9498 -0.0162 -0.19 0.8645 -0.018 -0.27 -0.3265 -0.9852 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J16 mock treatment 0.95 -0.0161 -0.19 0.8313 -0.0513 -0.77 -0.6786 -0.8549 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J17 mock treatment 0.9459 -0.0201 -0.24 0.8189 -0.0637 -0.96 -0.844 -0.8559 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J18 mock treatment 0.9076 -0.0585 -0.69 0.8117 -0.0709 -1.07 -1.2389 -0.9773 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J19 mock treatment 0.9287 -0.0374 -0.44 0.8594 -0.0231 -0.35 -0.5561 -0.9934 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J20 mock treatment 0.9182 -0.0478 -0.56 0.8528 -0.0297 -0.45 -0.7129 -0.9936 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J21 mock treatment 0.9314 -0.0346 -0.41 0.8303 -0.0522 -0.79 -0.8429 -0.9529 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J22 mock treatment 0.9147 -0.0514 -0.6 0.886 0.00346 0.05 -0.3898 -0.6437 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J23 mock treatment 0.9114 -0.0547 -0.64 0.8926 0.01 0.15 -0.3474 -0.5268 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base J24 mock treatment 0.9295 -0.0366 -0.43 0.9141 0.0316 0.47 0.0321 0.0502 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K01 mock treatment 1.1165 0.15 1.77 0.9017 0.0191 0.29 1.4519 0.8115 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K02 mock treatment 1.0758 0.11 1.29 0.9441 0.0615 0.93 1.5654 0.9868 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K03 mock treatment 1.0406 0.0745 0.87 0.9057 0.0232 0.35 0.8652 0.9188 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K04 mock treatment 1.0308 0.0648 0.76 0.9492 0.0667 1.0 1.2469 0.9907 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K05 mock treatment 1.0241 0.058 0.68 0.8971 0.0146 0.22 0.6363 0.8896 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K06 mock treatment 1.0266 0.0605 0.71 0.9141 0.0316 0.47 0.8378 0.9809 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K07 mock treatment 1.0125 0.0465 0.55 0.9158 0.0333 0.5 0.7396 0.9991 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K08 mock treatment 1.0172 0.0512 0.6 0.9074 0.0248 0.37 0.6887 0.9738 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K09 mock treatment 0.9944 0.0284 0.33 0.8826 9.44E-5 0.0 0.2364 0.7101 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K10 mock treatment 0.9697 0.00359 0.04 0.8656 -0.0169 -0.25 -0.1503 -0.5822 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K11 mock treatment 0.973 0.00699 0.08 0.9146 0.032 0.48 0.3987 0.8158 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K12 mock treatment 0.9646 -0.00149 -0.02 0.8626 -0.0199 -0.3 -0.2239 -0.7471 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K13 mock treatment 0.9477 -0.0183 -0.22 0.8647 -0.0179 -0.27 -0.3422 -0.9939 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K14 mock treatment 0.9536 -0.0125 -0.15 0.8851 0.00251 0.04 -0.0768 -0.5082 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K15 mock treatment 0.9654 -6.29E-4 -0.01 0.8574 -0.0251 -0.38 -0.2721 -0.7208 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K16 mock treatment 0.939 -0.0271 -0.32 0.8521 -0.0305 -0.46 -0.5484 -0.984 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K17 mock treatment 0.942 -0.0241 -0.28 0.8245 -0.0581 -0.87 -0.8172 -0.8905 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K18 mock treatment 0.9051 -0.061 -0.72 0.8598 -0.0227 -0.34 -0.7479 -0.9428 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K19 mock treatment 0.925 -0.0411 -0.48 0.8266 -0.0559 -0.84 -0.9352 -0.9651 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K20 mock treatment 0.906 -0.0601 -0.71 0.823 -0.0595 -0.89 -1.1312 -0.993 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K21 mock treatment 0.9025 -0.0636 -0.75 0.8102 -0.0724 -1.09 -1.2968 -0.983 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K22 mock treatment 0.9027 -0.0633 -0.74 0.8496 -0.033 -0.5 -0.876 -0.9806 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K23 mock treatment 0.9455 -0.0206 -0.24 0.8969 0.0143 0.22 -0.0184 -0.0568 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base K24 mock treatment 0.9629 -0.00313 -0.04 0.9215 0.039 0.59 0.3883 0.6615 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L01 mock treatment 1.117 0.151 1.77 0.9593 0.0768 1.15 2.0697 0.9785 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L02 mock treatment 1.0624 0.0963 1.13 0.9481 0.0655 0.99 1.4958 0.9977 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L03 mock treatment 1.0436 0.0775 0.91 0.9508 0.0682 1.03 1.3685 0.9982 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L04 mock treatment 1.0411 0.075 0.88 0.8843 0.00178 0.03 0.6418 0.7283 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L05 mock treatment 1.0305 0.0644 0.76 0.9391 0.0566 0.85 1.1363 0.9983 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L06 mock treatment 0.9927 0.0267 0.31 0.895 0.0124 0.19 0.3533 0.9695 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L07 mock treatment 0.9717 0.00562 0.07 0.895 0.0124 0.19 0.1788 0.9023 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L08 mock treatment 1.0257 0.0597 0.7 0.8901 0.00757 0.11 0.5758 0.8113 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L09 mock treatment 0.9919 0.0258 0.3 0.8825 -4.5E-5 0.0 0.2137 0.7055 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L10 mock treatment 0.9736 0.0075 0.09 0.8864 0.00384 0.06 0.1031 0.9792 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L11 mock treatment 0.9638 -0.00223 -0.03 0.8779 -0.00462 -0.07 -0.0677 -0.9112 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L12 mock treatment 0.9528 -0.0133 -0.16 0.871 -0.0115 -0.17 -0.2331 -0.9986 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L13 mock treatment 0.9583 -0.00774 -0.09 0.8995 0.0169 0.25 0.1158 0.4284 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L14 mock treatment 0.9662 1.12E-4 0.0 0.8742 -0.00839 -0.13 -0.0882 -0.6997 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L15 mock treatment 0.9294 -0.0367 -0.43 0.8417 -0.0409 -0.61 -0.7387 -0.9848 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L16 mock treatment 0.9336 -0.0325 -0.38 0.8366 -0.046 -0.69 -0.7583 -0.9606 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L17 mock treatment 0.9654 -6.17E-4 -0.01 0.8255 -0.057 -0.86 -0.6116 -0.713 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L18 mock treatment 0.9224 -0.0436 -0.51 0.8876 0.00504 0.08 -0.3085 -0.5959 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L19 mock treatment 0.9263 -0.0398 -0.47 0.8122 -0.0703 -1.06 -1.0778 -0.9325 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L20 mock treatment 0.9434 -0.0227 -0.27 0.8444 -0.0381 -0.57 -0.5936 -0.9392 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L21 mock treatment 0.9058 -0.0603 -0.71 0.8594 -0.0231 -0.35 -0.7466 -0.9466 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L22 mock treatment 0.8928 -0.0733 -0.86 0.6251 -0.257 -3.87 -3.346 -0.8437 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L23 mock treatment 0.9096 -0.0565 -0.66 0.8761 -0.00642 -0.1 -0.5367 -0.8016 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base L24 mock treatment 0.9722 0.00612 0.07 0.9006 0.0181 0.27 0.2432 0.8642 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M01 mock treatment 1.097 0.131 1.54 0.9831 0.101 1.51 2.1557 1.0 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M02 mock treatment 1.0322 0.0662 0.78 0.9263 0.0438 0.66 1.0147 0.9966 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M03 mock treatment 1.045 0.079 0.93 0.9316 0.0491 0.74 1.1773 0.9936 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M04 mock treatment 1.0414 0.0754 0.88 0.897 0.0144 0.22 0.7789 0.8554 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M05 mock treatment 1.0478 0.0818 0.96 0.8946 0.0121 0.18 0.8071 0.8263 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M06 mock treatment 1.0183 0.0522 0.61 0.9145 0.0319 0.48 0.773 0.9927 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M07 mock treatment 1.0038 0.0378 0.44 0.8987 0.0161 0.24 0.4852 0.9598 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M08 mock treatment 1.038 0.072 0.84 0.8663 -0.0163 -0.24 0.4243 0.4825 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M09 mock treatment 1.0212 0.0551 0.65 0.8302 -0.0524 -0.79 -0.0995 -0.0977 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M10 mock treatment 0.9973 0.0312 0.37 0.875 -0.00753 -0.11 0.1791 0.4669 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M11 mock treatment 0.9697 0.00366 0.04 0.8724 -0.0102 -0.15 -0.078 -0.4899 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M12 mock treatment 0.9533 -0.0127 -0.15 0.8546 -0.0279 -0.42 -0.4027 -0.9029 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M13 mock treatment 0.9355 -0.0305 -0.36 0.8456 -0.037 -0.56 -0.6464 -0.9775 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M14 mock treatment 0.9686 0.00252 0.03 0.8558 -0.0267 -0.4 -0.2629 -0.6532 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M15 mock treatment 0.9592 -0.00688 -0.08 0.8188 -0.0637 -0.96 -0.7345 -0.764 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M16 mock treatment 0.9488 -0.0173 -0.2 0.8104 -0.0721 -1.08 -0.9103 -0.825 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M17 mock treatment 0.9378 -0.0282 -0.33 0.8172 -0.0653 -0.98 -0.9289 -0.8961 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M18 mock treatment 0.9189 -0.0472 -0.55 0.8251 -0.0574 -0.86 -1.0019 -0.977 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M19 mock treatment 0.9039 -0.0622 -0.73 0.8035 -0.079 -1.19 -1.3564 -0.9725 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M20 mock treatment 0.9107 -0.0553 -0.65 0.8495 -0.0331 -0.5 -0.8108 -0.9913 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M21 mock treatment 0.8591 -0.107 -1.26 0.8759 -0.00661 -0.1 -0.9579 -0.7607 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M22 mock treatment 0.9136 -0.0524 -0.62 0.8465 -0.0361 -0.54 -0.8187 -0.998 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M23 mock treatment 0.904 -0.0621 -0.73 0.8603 -0.0222 -0.33 -0.7518 -0.9377 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base M24 mock treatment 0.9668 7.29E-4 0.01 0.8995 0.017 0.26 0.1868 0.7304 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N01 mock treatment 1.0905 0.124 1.46 1.0086 0.126 1.9 2.3734 0.9917 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N02 mock treatment 1.0413 0.0753 0.88 0.9528 0.0703 1.06 1.3719 0.996 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N03 mock treatment 1.0384 0.0723 0.85 0.9475 0.0649 0.98 1.2902 0.9976 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N04 mock treatment 1.039 0.0729 0.86 0.9328 0.0503 0.76 1.1397 0.9981 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N05 mock treatment 1.0336 0.0675 0.79 0.9193 0.0368 0.55 0.9513 0.9846 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N06 mock treatment 1.0346 0.0685 0.8 0.8868 0.00428 0.06 0.6144 0.7612 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N07 mock treatment 1.02 0.054 0.63 0.8957 0.0132 0.2 0.5885 0.8862 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N08 mock treatment 1.0311 0.0651 0.76 0.8646 -0.018 -0.27 0.3486 0.4304 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N09 mock treatment 1.0227 0.0567 0.67 0.8789 -0.00369 -0.06 0.4311 0.6459 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N10 mock treatment 0.9894 0.0234 0.27 0.8628 -0.0198 -0.3 -0.0162 -0.0402 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N11 mock treatment 0.9838 0.0178 0.21 0.9162 0.0337 0.51 0.5055 0.9231 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N12 mock treatment 0.967 9.65E-4 0.01 0.8552 -0.0273 -0.41 -0.2825 -0.6873 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N13 mock treatment 0.9689 0.0028 0.03 0.8699 -0.0126 -0.19 -0.1107 -0.5758 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N14 mock treatment 0.9609 -0.00513 -0.06 0.7936 -0.089 -1.34 -0.9886 -0.7382 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N15 mock treatment 0.9587 -0.00739 -0.09 0.8248 -0.0578 -0.87 -0.6754 -0.7738 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N16 mock treatment 0.9906 0.0246 0.29 0.8364 -0.0462 -0.69 -0.2872 -0.3819 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N17 mock treatment 0.9437 -0.0224 -0.26 0.8148 -0.0678 -1.02 -0.9065 -0.8613 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N18 mock treatment 0.9482 -0.0178 -0.21 0.8373 -0.0453 -0.68 -0.6292 -0.8836 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N19 mock treatment 0.942 -0.0241 -0.28 0.7849 -0.0976 -1.47 -1.2375 -0.828 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N20 mock treatment 0.9102 -0.0559 -0.66 0.8447 -0.0379 -0.57 -0.8665 -0.9975 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N21 mock treatment 0.9048 -0.0612 -0.72 0.8494 -0.0331 -0.5 -0.8603 -0.984 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N22 mock treatment 0.9076 -0.0584 -0.69 0.8521 -0.0304 -0.46 -0.8081 -0.9806 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N23 mock treatment 0.9465 -0.0195 -0.23 0.8805 -0.00206 -0.03 -0.1841 -0.7954 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base N24 mock treatment 0.9394 -0.0267 -0.31 0.9143 0.0318 0.48 0.1164 0.2038 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O01 mock treatment 1.0733 0.107 1.26 0.9982 0.116 1.74 2.1201 0.9874 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O02 mock treatment 1.0515 0.0854 1.0 0.9521 0.0696 1.05 1.4486 0.9998 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O03 mock treatment 1.0302 0.0641 0.75 0.6992 -0.183 -2.76 -1.4178 -0.496 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O04 mock treatment 1.05 0.084 0.99 0.9331 0.0506 0.76 1.2345 0.9918 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O05 mock treatment 1.0557 0.0896 1.05 0.9064 0.0239 0.36 0.9976 0.8975 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O06 mock treatment 1.0499 0.0839 0.98 0.9169 0.0344 0.52 1.0616 0.9548 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O07 mock treatment 0.9907 0.0246 0.29 0.9082 0.0256 0.39 0.4768 0.99 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O08 mock treatment 0.9974 0.0313 0.37 0.9039 0.0213 0.32 0.4867 0.9977 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O09 mock treatment 1.0074 0.0414 0.49 0.8819 -6.4E-4 -0.01 0.3367 0.693 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O10 mock treatment 0.9694 0.00339 0.04 0.9037 0.0212 0.32 0.2533 0.7893 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O11 mock treatment 0.9541 -0.0119 -0.14 0.8498 -0.0327 -0.49 -0.4468 -0.8735 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O12 mock treatment 0.9543 -0.0118 -0.14 0.9255 0.0429 0.65 0.3586 0.5433 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O13 mock treatment 0.9878 0.0218 0.26 0.8909 0.00838 0.13 0.2697 0.947 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O14 mock treatment 0.9822 0.0161 0.19 0.8824 -1.83E-4 0.0 0.1319 0.6967 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O15 mock treatment 0.957 -0.00903 -0.11 0.8714 -0.0111 -0.17 -0.1932 -0.9757 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O16 mock treatment 0.9884 0.0223 0.26 0.8486 -0.0339 -0.51 -0.175 -0.3052 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O17 mock treatment 0.9635 -0.00256 -0.03 0.8643 -0.0182 -0.27 -0.2152 -0.7798 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O18 mock treatment 0.9401 -0.0259 -0.3 0.8376 -0.045 -0.68 -0.6936 -0.9349 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O19 mock treatment 0.9468 -0.0193 -0.23 0.848 -0.0346 -0.52 -0.5278 -0.9306 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O20 mock treatment 0.9395 -0.0265 -0.31 0.8929 0.0104 0.16 -0.1097 -0.315 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O21 mock treatment 0.8637 -0.102 -1.2 0.8805 -0.00208 -0.03 -0.8713 -0.7253 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O22 mock treatment 0.9081 -0.058 -0.68 0.9054 0.0228 0.34 -0.2385 -0.313 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O23 mock treatment 0.9164 -0.0497 -0.58 0.9251 0.0426 0.64 0.0406 0.0469 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base O24 mock treatment 0.9336 -0.0325 -0.38 0.9124 0.0299 0.45 0.0484 0.0821 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P01 mock treatment 1.0065 0.0404 0.47 0.9476 0.0651 0.98 1.0276 0.9448 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P02 mock treatment 1.0199 0.0539 0.63 1.0087 0.126 1.9 1.789 0.8944 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P03 mock treatment 1.0501 0.084 0.99 0.9632 0.0806 1.21 1.5546 0.9947 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P04 mock treatment 1.0412 0.0751 0.88 0.8931 0.0105 0.16 0.7353 0.8211 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P05 mock treatment 1.0616 0.0955 1.12 0.9321 0.0495 0.74 1.3195 0.9802 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P06 mock treatment 1.0682 0.102 1.2 0.9219 0.0393 0.59 1.2658 0.947 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P07 mock treatment 1.0153 0.0492 0.58 0.9363 0.0537 0.81 0.9796 0.9865 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P08 mock treatment 1.0114 0.0454 0.53 0.9233 0.0407 0.61 0.8094 0.9976 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P09 mock treatment 1.0142 0.0481 0.56 0.8903 0.0078 0.12 0.4824 0.8361 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P10 mock treatment 0.9971 0.031 0.36 0.826 -0.0565 -0.85 -0.3437 -0.3717 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P11 mock treatment 1.0057 0.0397 0.47 0.9307 0.0481 0.72 0.841 0.9772 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P12 mock treatment 0.9872 0.0211 0.25 0.8925 0.00998 0.15 0.2816 0.971 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P13 mock treatment 0.9927 0.0267 0.31 0.8895 0.00698 0.11 0.2957 0.8953 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P14 mock treatment 1.0181 0.052 0.61 0.878 -0.00455 -0.07 0.3834 0.6239 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P15 mock treatment 0.9925 0.0264 0.31 0.8326 -0.0499 -0.75 -0.3114 -0.3834 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P16 mock treatment 1.015 0.049 0.57 0.8886 0.00603 0.09 0.4704 0.8086 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P17 mock treatment 0.9998 0.0338 0.4 0.8303 -0.0522 -0.79 -0.275 -0.3125 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P18 mock treatment 0.9796 0.0135 0.16 0.8738 -0.00877 -0.13 0.0189 0.0917 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P19 mock treatment 1.0107 0.0447 0.52 0.8447 -0.0379 -0.57 -0.0321 -0.0415 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P20 mock treatment 0.9698 0.00372 0.04 0.8608 -0.0218 -0.33 -0.2006 -0.6074 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P21 mock treatment 0.9468 -0.0193 -0.23 0.8486 -0.0339 -0.51 -0.5209 -0.9329 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P22 mock treatment 0.9213 -0.0447 -0.52 0.9276 0.045 0.68 0.1079 0.1259 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P23 mock treatment 0.9459 -0.0202 -0.24 0.9292 0.0466 0.7 0.3287 0.4441 1111.0016 Calc(E1/E2)(1111.0016) GSISyntheticLethal 1111.0016.Base P24 mock treatment 0.9865 0.0204 0.24 0.9442 0.0617 0.93 0.8251 0.8616