ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A01 compound treatment 1.05045144E8 1.34E7 0.69 1.08704677E8 9170000.0 0.49 0.8345 0.9869 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A02 compound treatment 1.04384939E8 1.27E7 0.65 1.05531057E8 5990000.0 0.32 0.6897 0.9473 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A03 compound treatment 1.0121023E8 9560000.0 0.49 1.04587803E8 5050000.0 0.27 0.5387 0.9615 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A04 compound treatment 1.1010156E8 1.84E7 0.95 1.16960711E8 1.74E7 0.94 1.3321 1.0 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A05 compound treatment 9.3356943E7 1700000.0 0.09 9.7403106E7 -2130000.0 -0.11 -0.0195 -0.1348 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A06 compound treatment 9.3669667E7 2020000.0 0.1 1.01675228E8 2140000.0 0.12 0.1546 0.9985 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A07 compound treatment 9.3397023E7 1740000.0 0.09 1.01846775E8 2310000.0 0.12 0.1512 0.9869 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A08 compound treatment 8.040201E7 -1.13E7 -0.58 9.1571807E7 -7960000.0 -0.43 -0.711 -0.9894 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A09 compound treatment 8.4851893E7 -6800000.0 -0.35 9.4143499E7 -5390000.0 -0.29 -0.4518 -0.9959 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A10 compound treatment 8.4548652E7 -7100000.0 -0.36 1.01136092E8 1600000.0 0.09 -0.1965 -0.5253 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A11 compound treatment 7.8658167E7 -1.3E7 -0.67 8.9545651E7 -9990000.0 -0.54 -0.8513 -0.9944 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A12 compound treatment 8.7423994E7 -4230000.0 -0.22 9.5904711E7 -3630000.0 -0.2 -0.2915 -0.9987 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A13 mock treatment 9.1089204E7 -563000.0 -0.03 1.05689786E8 6150000.0 0.33 0.2139 0.6431 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A14 mock treatment 8.5453936E7 -6200000.0 -0.32 9.4968809E7 -4570000.0 -0.25 -0.3986 -0.992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A15 compound treatment 8.3267844E7 -8380000.0 -0.43 9.5427428E7 -4110000.0 -0.22 -0.4603 -0.9524 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A16 compound treatment 8.3407209E7 -8250000.0 -0.42 1.01353218E8 1820000.0 0.1 -0.2296 -0.5294 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A17 compound treatment 8.6890096E7 -4760000.0 -0.24 9.6593609E7 -2940000.0 -0.16 -0.2846 -0.9781 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A18 compound treatment 9.4104181E7 2450000.0 0.13 1.1154945E8 1.2E7 0.65 0.5463 0.829 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A19 compound treatment 8.7436773E7 -4220000.0 -0.22 9.9491099E7 -45000.0 0.0 -0.1545 -0.715 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A20 compound treatment 9.4859015E7 3210000.0 0.16 1.02272861E8 2740000.0 0.15 0.2204 0.9985 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A21 compound treatment 8.9315912E7 -2340000.0 -0.12 9.5914262E7 -3620000.0 -0.2 -0.2226 -0.9726 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A22 compound treatment 9.8819844E7 7170000.0 0.37 1.02350192E8 2810000.0 0.15 0.3669 0.9233 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A23 compound treatment 1.03011153E8 1.14E7 0.58 1.07945912E8 8410000.0 0.45 0.7319 0.9923 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 A24 compound treatment 1.15778254E8 2.41E7 1.24 1.16026354E8 1.65E7 0.89 1.5023 0.9868 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B01 compound treatment 9.7554102E7 5900000.0 0.3 1.00612888E8 1080000.0 0.06 0.2549 0.8276 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B02 compound treatment 9.6696797E7 5040000.0 0.26 1.01217192E8 1680000.0 0.09 0.2468 0.9011 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B03 compound treatment 9.2685398E7 1030000.0 0.05 9.7302787E7 -2230000.0 -0.12 -0.0476 -0.3623 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B04 compound treatment 8.6567441E7 -5090000.0 -0.26 9.0793312E7 -8740000.0 -0.47 -0.5172 -0.9611 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B05 compound treatment 8.6032932E7 -5620000.0 -0.29 9.198061E7 -7560000.0 -0.41 -0.4914 -0.9857 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B06 compound treatment 8.0911707E7 -1.07E7 -0.55 8.6683311E7 -1.29E7 -0.69 -0.8787 -0.9936 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B07 compound treatment 8.3749592E7 -7900000.0 -0.41 8.9271654E7 -1.03E7 -0.55 -0.6773 -0.9883 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B08 compound treatment 8.0285362E7 -1.14E7 -0.58 9.2829664E7 -6710000.0 -0.36 -0.6673 -0.9736 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B09 compound treatment 8.0994041E7 -1.07E7 -0.55 9.2452584E7 -7080000.0 -0.38 -0.656 -0.9846 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B10 compound treatment 6.8021223E7 -2.36E7 -1.21 7.9640542E7 -1.99E7 -1.07 -1.614 -0.9981 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B11 compound treatment 7.7646814E7 -1.4E7 -0.72 8.5190066E7 -1.43E7 -0.77 -1.0539 -0.9993 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B12 compound treatment 7.5919233E7 -1.57E7 -0.81 8.6853997E7 -1.27E7 -0.68 -1.0531 -0.9966 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B13 mock treatment 8.0092473E7 -1.16E7 -0.59 8.4451257E7 -1.51E7 -0.81 -0.9934 -0.988 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B14 mock treatment 7.671319E7 -1.49E7 -0.77 8.3783718E7 -1.58E7 -0.85 -1.1412 -0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B15 compound treatment 7.6360811E7 -1.53E7 -0.78 8.5869261E7 -1.37E7 -0.74 -1.0746 -0.9995 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B16 compound treatment 6.8254624E7 -2.34E7 -1.2 8.1491578E7 -1.8E7 -0.97 -1.5351 -0.9946 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B17 compound treatment 7.8618858E7 -1.3E7 -0.67 8.5610665E7 -1.39E7 -0.75 -1.0026 -0.9983 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B18 compound treatment 7.6189186E7 -1.55E7 -0.79 8.7872055E7 -1.17E7 -0.63 -1.0046 -0.9934 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B19 compound treatment 8.3789713E7 -7860000.0 -0.4 8.8488918E7 -1.1E7 -0.59 -0.7056 -0.982 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B20 compound treatment 9.6815011E7 5160000.0 0.26 1.04678926E8 5140000.0 0.28 0.3829 0.9997 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B21 compound treatment 8.9823166E7 -1830000.0 -0.09 9.2388689E7 -7150000.0 -0.38 -0.3385 -0.8544 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B22 compound treatment 8.924797E7 -2400000.0 -0.12 9.2468164E7 -7070000.0 -0.38 -0.3563 -0.8905 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B23 compound treatment 1.00080672E8 8430000.0 0.43 1.01427273E8 1890000.0 0.1 0.3775 0.8505 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 B24 compound treatment 1.06699229E8 1.5E7 0.77 1.1025215E8 1.07E7 0.58 0.9534 0.9898 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C01 compound treatment 9.5227032E7 3570000.0 0.18 9.5683384E7 -3850000.0 -0.21 -0.0172 -0.062 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C02 compound treatment 8.7900063E7 -3750000.0 -0.19 8.7786E7 -1.18E7 -0.63 -0.5834 -0.8822 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C03 compound treatment 9.506538E7 3410000.0 0.17 9.670162E7 -2830000.0 -0.15 0.0158 0.0679 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C04 compound treatment 9.315245E7 1500000.0 0.08 9.8103553E7 -1430000.0 -0.08 -2.0E-4 -0.0018 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C05 compound treatment 8.7854415E7 -3800000.0 -0.19 9.94558E7 -80300.0 0.0 -0.1407 -0.7226 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C06 compound treatment 8.7243036E7 -4410000.0 -0.23 1.02334335E8 2800000.0 0.15 -0.0533 -0.1961 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C07 compound treatment 7.8736332E7 -1.29E7 -0.66 9.0613148E7 -8920000.0 -0.48 -0.8079 -0.9876 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C08 compound treatment 8.003944E7 -1.16E7 -0.6 9.2701895E7 -6830000.0 -0.37 -0.6811 -0.9733 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C09 compound treatment 8.9813184E7 -1840000.0 -0.09 1.01636869E8 2100000.0 0.11 0.0133 0.0905 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C10 compound treatment 7.6799704E7 -1.49E7 -0.76 8.6632496E7 -1.29E7 -0.69 -1.0296 -0.999 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C11 mock treatment 8.3562024E7 -8090000.0 -0.41 1.01257598E8 1720000.0 0.09 -0.2277 -0.5358 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C12 mock treatment 7.801268E7 -1.36E7 -0.7 8.9179271E7 -1.04E7 -0.56 -0.8887 -0.9937 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C13 compound treatment 7.7351529E7 -1.43E7 -0.73 9.1469667E7 -8070000.0 -0.43 -0.8254 -0.9688 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C14 compound treatment 6.2950522E7 -2.87E7 -1.47 6.7789333E7 -3.17E7 -1.71 -2.2491 -0.9972 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C15 mock treatment 7.4966886E7 -1.67E7 -0.86 8.7201477E7 -1.23E7 -0.66 -1.0744 -0.9922 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C16 mock treatment 7.117331E7 -2.05E7 -1.05 8.3686966E7 -1.58E7 -0.85 -1.3457 -0.9947 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C17 compound treatment 8.076595E7 -1.09E7 -0.56 9.7305981E7 -2230000.0 -0.12 -0.4795 -0.8401 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C18 compound treatment 5.981173E7 -3.18E7 -1.63 6.8130733E7 -3.14E7 -1.69 -2.3498 -0.9998 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C19 compound treatment 7.863968E7 -1.3E7 -0.67 8.611181E7 -1.34E7 -0.72 -0.9828 -0.9992 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C20 compound treatment 8.6697602E7 -4950000.0 -0.25 8.9293912E7 -1.02E7 -0.55 -0.5696 -0.938 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C21 compound treatment 8.8826354E7 -2830000.0 -0.14 9.0322598E7 -9210000.0 -0.5 -0.4533 -0.8769 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C22 compound treatment 8.6632187E7 -5020000.0 -0.26 8.837599E7 -1.12E7 -0.6 -0.6069 -0.9283 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C23 compound treatment 9.4480178E7 2830000.0 0.14 9.5920706E7 -3620000.0 -0.19 -0.0352 -0.145 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 C24 compound treatment 1.10084341E8 1.84E7 0.94 1.11663322E8 1.21E7 0.65 1.1298 0.9837 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D01 compound treatment 1.05036172E8 1.34E7 0.69 1.07519499E8 7980000.0 0.43 0.789 0.9747 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D02 compound treatment 9.0481126E7 -1170000.0 -0.06 8.7862303E7 -1.17E7 -0.63 -0.487 -0.7711 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D03 compound treatment 9.7084597E7 5430000.0 0.28 9.5924328E7 -3610000.0 -0.19 0.0593 0.1747 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D04 compound treatment 8.6492356E7 -5160000.0 -0.26 9.0146797E7 -9390000.0 -0.51 -0.5445 -0.9543 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D05 compound treatment 8.7400112E7 -4250000.0 -0.22 9.8000901E7 -1540000.0 -0.08 -0.2126 -0.9119 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D06 compound treatment 7.9241678E7 -1.24E7 -0.64 9.0687167E7 -8850000.0 -0.48 -0.7867 -0.9899 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D07 compound treatment 8.6099796E7 -5550000.0 -0.28 9.9283484E7 -253000.0 -0.01 -0.2109 -0.7401 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D08 compound treatment 8.330483E7 -8350000.0 -0.43 9.6124325E7 -3410000.0 -0.18 -0.4324 -0.9287 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D09 compound treatment 8.2009573E7 -9640000.0 -0.49 9.5061703E7 -4470000.0 -0.24 -0.5198 -0.9455 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D10 compound treatment 7.6926668E7 -1.47E7 -0.75 9.3932762E7 -5600000.0 -0.3 -0.747 -0.9191 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D11 mock treatment 8.1125082E7 -1.05E7 -0.54 9.4128193E7 -5410000.0 -0.29 -0.5875 -0.9581 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D12 mock treatment 8.987902E7 -1770000.0 -0.09 9.9875665E7 340000.0 0.02 -0.0513 -0.5538 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D13 compound treatment 7.9944852E7 -1.17E7 -0.6 9.1646288E7 -7890000.0 -0.42 -0.7247 -0.9857 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D14 compound treatment 7.4855029E7 -1.68E7 -0.86 8.8584977E7 -1.1E7 -0.59 -1.0258 -0.983 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D15 mock treatment 7.3683806E7 -1.8E7 -0.92 9.074497E7 -8790000.0 -0.47 -0.986 -0.9522 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D16 mock treatment 8.2084856E7 -9570000.0 -0.49 9.8451198E7 -1080000.0 -0.06 -0.3881 -0.7858 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D17 compound treatment 7.4431242E7 -1.72E7 -0.88 9.305968E7 -6480000.0 -0.35 -0.8707 -0.9175 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D18 compound treatment 7.7469188E7 -1.42E7 -0.73 9.6559377E7 -2980000.0 -0.16 -0.6274 -0.8428 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D19 compound treatment 7.9076648E7 -1.26E7 -0.64 9.3379831E7 -6160000.0 -0.33 -0.6902 -0.9522 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D20 compound treatment 7.0963802E7 -2.07E7 -1.06 8.4822422E7 -1.47E7 -0.79 -1.3101 -0.9897 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D21 compound treatment 8.6560524E7 -5090000.0 -0.26 9.2313587E7 -7220000.0 -0.39 -0.4596 -0.9812 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D22 compound treatment 9.2785132E7 1130000.0 0.06 9.5541309E7 -3990000.0 -0.22 -0.1111 -0.4985 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D23 compound treatment 9.247004E7 818000.0 0.04 9.8846182E7 -690000.0 -0.04 0.0034 0.0599 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 D24 compound treatment 1.06552844E8 1.49E7 0.76 1.1183491E8 1.23E7 0.66 1.0083 0.9975 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E01 mock treatment 1.03935676E8 1.23E7 0.63 1.02741286E8 3210000.0 0.17 0.5672 0.8689 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E02 mock treatment 9.672711E7 5070000.0 0.26 9.3692374E7 -5840000.0 -0.31 -0.0386 -0.0946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E03 compound treatment 1.01726849E8 1.01E7 0.52 1.05902036E8 6370000.0 0.34 0.6075 0.9802 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E04 compound treatment 9.230138E7 649000.0 0.03 1.02804692E8 3270000.0 0.18 0.148 0.8261 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E05 compound treatment 8.7061961E7 -4590000.0 -0.24 1.02018378E8 2480000.0 0.13 -0.0718 -0.2655 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E06 compound treatment 9.6720219E7 5070000.0 0.26 1.06759184E8 7220000.0 0.39 0.4587 0.9807 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E07 compound treatment 8.4180571E7 -7470000.0 -0.38 9.4678707E7 -4860000.0 -0.26 -0.4558 -0.9827 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E08 compound treatment 9.0871733E7 -781000.0 -0.04 1.00690497E8 1150000.0 0.06 0.0157 0.2118 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E09 mock treatment 8.5145601E7 -6510000.0 -0.33 1.01471458E8 1940000.0 0.1 -0.1621 -0.464 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E10 mock treatment 8.9243924E7 -2410000.0 -0.12 9.5186448E7 -4350000.0 -0.23 -0.2529 -0.9552 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E11 compound treatment 8.1535628E7 -1.01E7 -0.52 9.4453505E7 -5080000.0 -0.27 -0.5602 -0.9554 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E12 compound treatment 9.1548834E7 -104000.0 -0.01 1.02306303E8 2770000.0 0.15 0.1017 0.6815 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E13 compound treatment 8.7388846E7 -4260000.0 -0.22 9.7217631E7 -2320000.0 -0.12 -0.2428 -0.9647 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E14 compound treatment 8.4995122E7 -6660000.0 -0.34 9.7509529E7 -2030000.0 -0.11 -0.3184 -0.8889 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E15 compound treatment 7.7849966E7 -1.38E7 -0.71 9.7457387E7 -2080000.0 -0.11 -0.5794 -0.8089 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E16 compound treatment 4.9162363E7 -4.25E7 -2.18 5.4910202E7 -4.46E7 -2.4 -3.2392 -0.9988 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E17 mock treatment 8.2797091E7 -8860000.0 -0.45 9.7660888E7 -1880000.0 -0.1 -0.3923 -0.8438 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E18 mock treatment 8.4568172E7 -7080000.0 -0.36 9.7660831E7 -1880000.0 -0.1 -0.3282 -0.8707 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E19 compound treatment 9.0574205E7 -1080000.0 -0.06 1.01508481E8 1970000.0 0.11 0.036 0.3009 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E20 compound treatment 9.357263E7 1920000.0 0.1 9.9292961E7 -243000.0 -0.01 0.0603 0.6077 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E21 compound treatment 8.3227892E7 -8420000.0 -0.43 9.5309569E7 -4230000.0 -0.23 -0.4663 -0.9553 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E22 compound treatment 9.8884936E7 7230000.0 0.37 1.05414074E8 5880000.0 0.32 0.4859 0.9969 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E23 compound treatment 8.9108067E7 -2540000.0 -0.13 9.2351607E7 -7180000.0 -0.39 -0.3658 -0.8959 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 E24 compound treatment 9.7642504E7 5990000.0 0.31 1.01350884E8 1810000.0 0.1 0.2862 0.8883 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F01 mock treatment 1.0279158E8 1.11E7 0.57 1.14107714E8 1.46E7 0.78 0.9586 0.9878 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F02 mock treatment 1.05465548E8 1.38E7 0.71 1.09893755E8 1.04E7 0.56 0.895 0.993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F03 compound treatment 9.0513241E7 -1140000.0 -0.06 8.8200065E7 -1.13E7 -0.61 -0.4729 -0.7712 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F04 compound treatment 8.9020858E7 -2630000.0 -0.13 9.1536556E7 -8000000.0 -0.43 -0.4 -0.8861 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F05 compound treatment 9.3277625E7 1630000.0 0.08 1.01837129E8 2300000.0 0.12 0.1465 0.9813 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F06 compound treatment 8.9749452E7 -1900000.0 -0.1 1.01757647E8 2220000.0 0.12 0.0156 0.1012 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F07 compound treatment 9.3896712E7 2240000.0 0.12 1.04142604E8 4610000.0 0.25 0.2567 0.939 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F08 compound treatment 8.5253723E7 -6400000.0 -0.33 9.5849419E7 -3690000.0 -0.2 -0.3723 -0.9711 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F09 mock treatment 8.9252398E7 -2400000.0 -0.12 9.9429762E7 -106000.0 -0.01 -0.091 -0.7392 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F10 mock treatment 8.5005305E7 -6650000.0 -0.34 9.6215894E7 -3320000.0 -0.18 -0.3673 -0.9547 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F11 compound treatment 8.6875411E7 -4780000.0 -0.24 9.6712914E7 -2820000.0 -0.15 -0.2806 -0.9737 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F12 compound treatment 8.8826636E7 -2830000.0 -0.14 9.5995021E7 -3540000.0 -0.19 -0.2373 -0.9908 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F13 compound treatment 8.8956841E7 -2700000.0 -0.14 9.9140395E7 -396000.0 -0.02 -0.1128 -0.8066 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F14 compound treatment 8.3880725E7 -7770000.0 -0.4 9.6199272E7 -3340000.0 -0.18 -0.4087 -0.9353 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F15 compound treatment 8.0776024E7 -1.09E7 -0.56 9.5190376E7 -4350000.0 -0.23 -0.5597 -0.9257 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F16 compound treatment 6.6124491E7 -2.55E7 -1.31 7.8857779E7 -2.07E7 -1.11 -1.7126 -0.9968 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F17 mock treatment 7.986861E7 -1.18E7 -0.6 9.7351166E7 -2180000.0 -0.12 -0.5103 -0.8293 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F18 mock treatment 8.6044612E7 -5610000.0 -0.29 9.723708E7 -2300000.0 -0.12 -0.2908 -0.9292 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F19 compound treatment 8.6698734E7 -4950000.0 -0.25 9.4208848E7 -5330000.0 -0.29 -0.3824 -0.9981 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F20 compound treatment 9.3378286E7 1730000.0 0.09 9.8681086E7 -855000.0 -0.05 0.03 0.3007 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F21 compound treatment 9.1798462E7 146000.0 0.01 9.8772614E7 -764000.0 -0.04 -0.0238 -0.5691 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F22 compound treatment 9.0756814E7 -896000.0 -0.05 9.9128722E7 -407000.0 -0.02 -0.048 -0.9429 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F23 compound treatment 8.7835987E7 -3820000.0 -0.2 9.9896362E7 360000.0 0.02 -0.1246 -0.6339 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 F24 compound treatment 1.12090981E8 2.04E7 1.05 1.17752236E8 1.82E7 0.98 1.4344 0.9995 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G01 compound treatment 1.03141018E8 1.15E7 0.59 1.00119942E8 584000.0 0.03 0.4386 0.7438 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G02 compound treatment 4.2782796E7 -4.89E7 -2.5 4.9688401E7 -4.98E7 -2.68 -3.6692 -0.9994 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G03 mock treatment 9.4277702E7 2630000.0 0.13 1.08535928E8 9000000.0 0.48 0.4378 0.8705 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G04 mock treatment 9.8610652E7 6960000.0 0.36 1.04143833E8 4610000.0 0.25 0.4276 0.9843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G05 compound treatment 9.7048649E7 5400000.0 0.28 1.03167379E8 3630000.0 0.2 0.3338 0.9856 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G06 compound treatment 9.3785285E7 2130000.0 0.11 1.00876043E8 1340000.0 0.07 0.1283 0.9797 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G07 compound treatment 8.8819912E7 -2830000.0 -0.15 9.1503351E7 -8030000.0 -0.43 -0.4085 -0.8953 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G08 compound treatment 9.3839429E7 2190000.0 0.11 1.00800213E8 1260000.0 0.07 0.1274 0.9714 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G09 compound treatment 8.6234185E7 -5420000.0 -0.28 9.7917618E7 -1620000.0 -0.09 -0.258 -0.8864 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G10 compound treatment 9.0729336E7 -923000.0 -0.05 1.01925555E8 2390000.0 0.13 0.0575 0.4196 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G11 compound treatment 8.7070486E7 -4580000.0 -0.23 9.4915864E7 -4620000.0 -0.25 -0.342 -0.9996 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G12 compound treatment 7.0699475E7 -2.1E7 -1.07 7.9892542E7 -1.96E7 -1.06 -1.5074 -1.0 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G13 compound treatment 9.0345605E7 -1310000.0 -0.07 1.00662932E8 1130000.0 0.06 -0.0045 -0.0493 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G14 compound treatment 8.2612033E7 -9040000.0 -0.46 9.6302814E7 -3230000.0 -0.17 -0.4508 -0.9106 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G15 compound treatment 8.5373105E7 -6280000.0 -0.32 9.8929798E7 -606000.0 -0.03 -0.2507 -0.7749 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G16 compound treatment 8.304693E7 -8610000.0 -0.44 9.1329445E7 -8210000.0 -0.44 -0.6244 -1.0 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G17 compound treatment 8.613052E7 -5520000.0 -0.28 9.7714376E7 -1820000.0 -0.1 -0.2695 -0.8997 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G18 compound treatment 8.5197265E7 -6460000.0 -0.33 9.6895033E7 -2640000.0 -0.14 -0.3345 -0.9289 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G19 mock treatment 8.9319367E7 -2330000.0 -0.12 9.8228427E7 -1310000.0 -0.07 -0.1344 -0.9681 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G20 mock treatment 9.0951447E7 -701000.0 -0.04 9.5986668E7 -3550000.0 -0.19 -0.1606 -0.8256 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G21 compound treatment 9.1202161E7 -450000.0 -0.02 1.0205145E8 2520000.0 0.14 0.0795 0.5783 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G22 compound treatment 9.1498497E7 -154000.0 -0.01 9.9664179E7 128000.0 0.01 -7.0E-4 -0.0674 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G23 compound treatment 8.7621516E7 -4030000.0 -0.21 1.02658735E8 3120000.0 0.17 -0.0272 -0.102 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 G24 compound treatment 1.00974984E8 9320000.0 0.48 1.02842468E8 3310000.0 0.18 0.4638 0.9095 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H01 compound treatment 1.00275186E8 8620000.0 0.44 1.03140578E8 3600000.0 0.19 0.4497 0.9318 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H02 compound treatment 9.3427904E7 1780000.0 0.09 9.2811628E7 -6720000.0 -0.36 -0.1917 -0.5135 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H03 mock treatment 9.6513479E7 4860000.0 0.25 1.01662241E8 2130000.0 0.11 0.2571 0.9378 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H04 mock treatment 1.00989092E8 9340000.0 0.48 1.00804349E8 1270000.0 0.07 0.3867 0.7999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H05 compound treatment 8.5697242E7 -5960000.0 -0.31 9.7216287E7 -2320000.0 -0.12 -0.3042 -0.9223 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H06 compound treatment 9.2774254E7 1120000.0 0.06 9.5352412E7 -4180000.0 -0.23 -0.1187 -0.5103 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H07 compound treatment 9.2660673E7 1010000.0 0.05 1.02310844E8 2770000.0 0.15 0.1422 0.8994 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H08 compound treatment 9.3259803E7 1610000.0 0.08 9.8749503E7 -787000.0 -0.04 0.0283 0.3055 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H09 compound treatment 9.1164944E7 -488000.0 -0.02 9.5622064E7 -3910000.0 -0.21 -0.1667 -0.7854 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H10 compound treatment 8.780659E7 -3850000.0 -0.2 9.6046615E7 -3490000.0 -0.19 -0.2723 -0.9997 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H11 compound treatment 8.5811321E7 -5840000.0 -0.3 9.3857403E7 -5680000.0 -0.31 -0.4279 -0.9999 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H12 compound treatment 6.6688758E7 -2.5E7 -1.28 7.3963959E7 -2.56E7 -1.38 -1.8785 -0.9993 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H13 compound treatment 8.7746732E7 -3910000.0 -0.2 9.8459681E7 -1080000.0 -0.06 -0.1825 -0.8759 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H14 compound treatment 8.4200567E7 -7450000.0 -0.38 9.4377967E7 -5160000.0 -0.28 -0.4665 -0.9878 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H15 compound treatment 8.6663491E7 -4990000.0 -0.26 9.9501953E7 -34200.0 0.0 -0.1821 -0.7122 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H16 compound treatment 8.2477626E7 -9170000.0 -0.47 9.1958752E7 -7580000.0 -0.41 -0.621 -0.9975 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H17 compound treatment 8.8822147E7 -2830000.0 -0.15 9.8411218E7 -1120000.0 -0.06 -0.1454 -0.925 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H18 compound treatment 8.365944E7 -7990000.0 -0.41 9.4502503E7 -5030000.0 -0.27 -0.4813 -0.9799 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H19 mock treatment 9.2241324E7 589000.0 0.03 9.9354678E7 -181000.0 -0.01 0.0144 0.4549 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H20 mock treatment 8.9711367E7 -1940000.0 -0.1 9.6132739E7 -3400000.0 -0.18 -0.1999 -0.9588 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H21 compound treatment 7.6044437E7 -1.56E7 -0.8 8.6363581E7 -1.32E7 -0.71 -1.0672 -0.9982 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H22 compound treatment 8.719058E7 -4460000.0 -0.23 9.0552151E7 -8980000.0 -0.48 -0.5038 -0.9415 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H23 compound treatment 9.8495919E7 6840000.0 0.35 1.08870366E8 9330000.0 0.5 0.6034 0.9845 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 H24 compound treatment 1.11179533E8 1.95E7 1.0 1.16428495E8 1.69E7 0.91 1.3509 0.9989 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I01 compound treatment 1.01114414E8 9460000.0 0.48 1.00823258E8 1290000.0 0.07 0.3919 0.8 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I02 compound treatment 9.3719703E7 2070000.0 0.11 1.0738051E8 7840000.0 0.42 0.3736 0.8579 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I03 compound treatment 9.8094648E7 6440000.0 0.33 1.01916798E8 2380000.0 0.13 0.3241 0.9151 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I04 compound treatment 9.7952767E7 6300000.0 0.32 1.03244346E8 3710000.0 0.2 0.3695 0.9733 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I05 mock treatment 9.3310166E7 1660000.0 0.08 9.7452039E7 -2080000.0 -0.11 -0.0193 -0.137 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I06 mock treatment 9.2200553E7 548000.0 0.03 9.9416561E7 -120000.0 -0.01 0.0153 0.5312 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I07 compound treatment 9.3638768E7 1990000.0 0.1 1.03299993E8 3760000.0 0.2 0.2153 0.9493 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I08 compound treatment 8.8505201E7 -3150000.0 -0.16 9.6016109E7 -3520000.0 -0.19 -0.2481 -0.9968 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I09 compound treatment 8.1561923E7 -1.01E7 -0.52 9.0823999E7 -8710000.0 -0.47 -0.6974 -0.9988 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I10 compound treatment 8.0312077E7 -1.13E7 -0.58 9.0410243E7 -9130000.0 -0.49 -0.7585 -0.9965 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I11 compound treatment 9.2068916E7 416000.0 0.02 1.03114612E8 3580000.0 0.19 0.1514 0.7806 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I12 compound treatment 8.4919859E7 -6730000.0 -0.35 9.3560135E7 -5980000.0 -0.32 -0.4716 -0.9994 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I13 compound treatment 8.2958406E7 -8690000.0 -0.45 9.4390632E7 -5150000.0 -0.28 -0.511 -0.9739 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I14 compound treatment 8.6803638E7 -4850000.0 -0.25 9.5276263E7 -4260000.0 -0.23 -0.3379 -0.9992 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I15 compound treatment 9.0812266E7 -840000.0 -0.04 1.01664084E8 2130000.0 0.11 0.0506 0.4132 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I16 compound treatment 8.3453801E7 -8200000.0 -0.42 9.6378255E7 -3160000.0 -0.17 -0.4174 -0.9207 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I17 compound treatment 8.541531E7 -6240000.0 -0.32 9.7948397E7 -1590000.0 -0.09 -0.2865 -0.8658 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I18 compound treatment 5.3390475E7 -3.83E7 -1.96 6.2336032E7 -3.72E7 -2.0 -2.8032 -0.9999 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I19 compound treatment 8.886849E7 -2780000.0 -0.14 9.616812E7 -3370000.0 -0.18 -0.2291 -0.993 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I20 compound treatment 9.484294E7 3190000.0 0.16 1.00877904E8 1340000.0 0.07 0.1667 0.9326 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I21 mock treatment 9.160867E7 -43800.0 0.0 9.7052008E7 -2480000.0 -0.13 -0.0962 -0.7189 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I22 mock treatment 9.6258242E7 4610000.0 0.24 1.00962346E8 1430000.0 0.08 0.2212 0.8912 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I23 compound treatment 9.5035261E7 3380000.0 0.17 1.04228111E8 4690000.0 0.25 0.3013 0.9831 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 I24 compound treatment 1.04137243E8 1.25E7 0.64 1.09324638E8 9790000.0 0.53 0.8252 0.9954 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J01 compound treatment 1.08375411E8 1.67E7 0.86 1.08059037E8 8520000.0 0.46 0.9306 0.9572 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J02 compound treatment 7.091556E7 -2.07E7 -1.06 8.0401704E7 -1.91E7 -1.03 -1.4801 -0.9999 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J03 compound treatment 9.604042E7 4390000.0 0.22 9.3212103E7 -6320000.0 -0.34 -0.0818 -0.2004 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J04 compound treatment 9.4716438E7 3060000.0 0.16 1.01126192E8 1590000.0 0.09 0.1716 0.9593 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J05 mock treatment 9.4736841E7 3080000.0 0.16 9.6231439E7 -3300000.0 -0.18 -0.0141 -0.0591 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J06 mock treatment 9.4479123E7 2830000.0 0.14 1.05873171E8 6340000.0 0.34 0.3437 0.9272 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J07 compound treatment 9.0571433E7 -1080000.0 -0.06 9.7647846E7 -1890000.0 -0.1 -0.1111 -0.9592 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J08 compound treatment 5.492385E7 -3.67E7 -1.88 5.5695271E7 -4.38E7 -2.36 -3.0005 -0.9937 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J09 compound treatment 9.4388019E7 2740000.0 0.14 1.03352017E8 3820000.0 0.21 0.2444 0.9826 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J10 compound treatment 8.6891909E7 -4760000.0 -0.24 9.9409961E7 -126000.0 -0.01 -0.1773 -0.7265 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J11 compound treatment 9.1497619E7 -155000.0 -0.01 1.01296563E8 1760000.0 0.09 0.0614 0.6456 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J12 compound treatment 8.2301793E7 -9350000.0 -0.48 9.0609567E7 -8930000.0 -0.48 -0.6788 -1.0 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J13 compound treatment 8.4448619E7 -7200000.0 -0.37 9.9523082E7 -13100.0 0.0 -0.2616 -0.7085 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J14 compound treatment 4.0237136E7 -5.14E7 -2.64 4.1186743E7 -5.83E7 -3.14 -4.0852 -0.9962 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J15 compound treatment 8.562488E7 -6030000.0 -0.31 9.597849E7 -3560000.0 -0.19 -0.3539 -0.9736 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J16 compound treatment 6.7979066E7 -2.37E7 -1.21 7.6167332E7 -2.34E7 -1.26 -1.7478 -0.9998 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J17 compound treatment 8.8905343E7 -2750000.0 -0.14 9.7698158E7 -1840000.0 -0.1 -0.1695 -0.9851 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J18 compound treatment 7.2131541E7 -1.95E7 -1.0 7.1884748E7 -2.77E7 -1.49 -1.7604 -0.9813 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J19 compound treatment 8.6498993E7 -5150000.0 -0.26 9.7365893E7 -2170000.0 -0.12 -0.2694 -0.9328 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J20 compound treatment 8.2206421E7 -9450000.0 -0.48 8.5229319E7 -1.43E7 -0.77 -0.8871 -0.9749 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J21 mock treatment 9.1563703E7 -88800.0 0.0 9.9582857E7 46700.0 0.0 -0.0014 -0.2768 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J22 mock treatment 9.3051727E7 1400000.0 0.07 1.01021506E8 1490000.0 0.08 0.1073 0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J23 compound treatment 1.04245874E8 1.26E7 0.65 1.11080591E8 1.15E7 0.62 0.896 0.9998 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 J24 compound treatment 1.07625829E8 1.6E7 0.82 1.0912137E8 9590000.0 0.52 0.9439 0.9753 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K01 compound treatment 1.00488641E8 8840000.0 0.45 9.90022E7 -534000.0 -0.03 0.2999 0.6609 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K02 compound treatment 8.9055625E7 -2600000.0 -0.13 9.1530019E7 -8010000.0 -0.43 -0.399 -0.8842 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K03 compound treatment 5.4828732E7 -3.68E7 -1.89 5.6361085E7 -4.32E7 -2.33 -2.9786 -0.9946 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K04 compound treatment 9.768693E7 6030000.0 0.31 1.06103252E8 6570000.0 0.35 0.4688 0.9978 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K05 compound treatment 8.9201753E7 -2450000.0 -0.13 9.3179186E7 -6360000.0 -0.34 -0.3309 -0.9074 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K06 compound treatment 9.5137116E7 3480000.0 0.18 1.03877502E8 4340000.0 0.23 0.2916 0.9912 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K07 mock treatment 9.1851374E7 199000.0 0.01 9.5551109E7 -3990000.0 -0.21 -0.1445 -0.6728 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K08 mock treatment 8.9898552E7 -1750000.0 -0.09 9.4361028E7 -5180000.0 -0.28 -0.2606 -0.89 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K09 compound treatment 8.6130701E7 -5520000.0 -0.28 9.3414439E7 -6120000.0 -0.33 -0.4332 -0.9971 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K10 compound treatment 4.1843772E7 -4.98E7 -2.55 6.1445864E7 -3.81E7 -2.05 -3.2555 -0.9941 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K11 compound treatment 8.6667331E7 -4990000.0 -0.26 9.5830725E7 -3710000.0 -0.2 -0.3218 -0.9925 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K12 compound treatment 7.8335915E7 -1.33E7 -0.68 8.4252519E7 -1.53E7 -0.82 -1.0646 -0.9957 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K13 compound treatment 8.5001081E7 -6650000.0 -0.34 9.0821454E7 -8710000.0 -0.47 -0.5729 -0.9877 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K14 compound treatment 8.5458546E7 -6190000.0 -0.32 9.7747747E7 -1790000.0 -0.1 -0.2926 -0.8819 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K15 mock treatment 8.6140125E7 -5510000.0 -0.28 9.4424931E7 -5110000.0 -0.28 -0.3944 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K16 mock treatment 8.4091233E7 -7560000.0 -0.39 9.7217871E7 -2320000.0 -0.12 -0.3623 -0.8899 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K17 compound treatment 8.9395328E7 -2260000.0 -0.12 9.8442947E7 -1090000.0 -0.06 -0.1234 -0.9509 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K18 compound treatment 8.484117E7 -6810000.0 -0.35 9.8472384E7 -1060000.0 -0.06 -0.2874 -0.8123 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K19 compound treatment 8.4504882E7 -7150000.0 -0.37 9.2117063E7 -7420000.0 -0.4 -0.5415 -0.9991 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K20 compound treatment 9.6570268E7 4920000.0 0.25 1.02243518E8 2710000.0 0.15 0.2813 0.9661 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K21 compound treatment 8.5427677E7 -6220000.0 -0.32 9.2449944E7 -7090000.0 -0.38 -0.4954 -0.996 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K22 compound treatment 9.4379428E7 2730000.0 0.14 9.7430807E7 -2110000.0 -0.11 0.0187 0.1037 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K23 mock treatment 9.4286762E7 2630000.0 0.14 1.04387859E8 4850000.0 0.26 0.2802 0.9528 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 K24 mock treatment 1.08026676E8 1.64E7 0.84 1.16421504E8 1.69E7 0.91 1.2364 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L01 compound treatment 1.02305734E8 1.07E7 0.55 1.10465423E8 1.09E7 0.59 0.8023 0.9993 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L02 compound treatment 4.4688764E7 -4.7E7 -2.41 4.160286E7 -5.79E7 -3.12 -3.908 -0.9918 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L03 compound treatment 1.04461603E8 1.28E7 0.66 1.06333322E8 6800000.0 0.37 0.723 0.9619 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L04 compound treatment 7.0785583E7 -2.09E7 -1.07 7.2781539E7 -2.68E7 -1.44 -1.775 -0.9892 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L05 compound treatment 9.7450642E7 5800000.0 0.3 1.0571426E8 6180000.0 0.33 0.4454 0.9984 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L06 compound treatment 8.0842503E7 -1.08E7 -0.55 9.1327304E7 -8210000.0 -0.44 -0.7043 -0.9937 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L07 mock treatment 8.7760543E7 -3890000.0 -0.2 9.6413303E7 -3120000.0 -0.17 -0.26 -0.9964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L08 mock treatment 8.664688E7 -5010000.0 -0.26 9.3077923E7 -6460000.0 -0.35 -0.4273 -0.9888 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L09 compound treatment 8.9339474E7 -2310000.0 -0.12 9.8965773E7 -570000.0 -0.03 -0.1055 -0.8619 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L10 compound treatment 7.567441E7 -1.6E7 -0.82 8.4308088E7 -1.52E7 -0.82 -1.1589 -1.0 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L11 compound treatment 8.2721227E7 -8930000.0 -0.46 9.5684243E7 -3850000.0 -0.21 -0.4704 -0.9359 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L12 compound treatment 8.5498417E7 -6150000.0 -0.32 9.3151924E7 -6380000.0 -0.34 -0.4661 -0.9991 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L13 compound treatment 8.4985527E7 -6670000.0 -0.34 9.9292987E7 -243000.0 -0.01 -0.2509 -0.7337 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L14 compound treatment 6.7413472E7 -2.42E7 -1.24 7.3811806E7 -2.57E7 -1.39 -1.858 -0.9985 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L15 mock treatment 8.5349748E7 -6300000.0 -0.32 9.4399197E7 -5140000.0 -0.28 -0.424 -0.997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L16 mock treatment 8.527962E7 -6370000.0 -0.33 9.2540264E7 -7000000.0 -0.38 -0.4974 -0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L17 compound treatment 9.2521971E7 869000.0 0.04 9.8683937E7 -852000.0 -0.05 -9.0E-4 -0.0147 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L18 compound treatment 6.5248146E7 -2.64E7 -1.35 6.4232242E7 -3.53E7 -1.9 -2.3012 -0.9861 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L19 compound treatment 9.071116E7 -941000.0 -0.05 1.00343339E8 807000.0 0.04 -0.0034 -0.052 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L20 compound treatment 8.6637804E7 -5010000.0 -0.26 8.9112805E7 -1.04E7 -0.56 -0.5786 -0.9373 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L21 compound treatment 9.171618E7 63700.0 0.0 9.8091976E7 -1440000.0 -0.08 -0.0527 -0.6768 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L22 compound treatment 8.0278991E7 -1.14E7 -0.58 8.0900603E7 -1.86E7 -1.0 -1.1218 -0.9666 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L23 mock treatment 9.6806103E7 5150000.0 0.26 1.05951588E8 6420000.0 0.35 0.4311 0.9912 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 L24 mock treatment 1.09468429E8 1.78E7 0.91 1.1521697E8 1.57E7 0.84 1.2428 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M01 compound treatment 1.10735438E8 1.91E7 0.98 1.12382069E8 1.28E7 0.69 1.1807 0.9856 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M02 compound treatment 9.9177753E7 7530000.0 0.39 1.05621431E8 6090000.0 0.33 0.5044 0.9967 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M03 compound treatment 9.5175881E7 3520000.0 0.18 1.00375922E8 840000.0 0.05 0.1597 0.8577 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M04 compound treatment 9.1298227E7 -354000.0 -0.02 9.7159575E7 -2380000.0 -0.13 -0.1033 -0.7994 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M05 compound treatment 9.8810878E7 7160000.0 0.37 1.05103109E8 5570000.0 0.3 0.4714 0.995 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M06 compound treatment 7.5856748E7 -1.58E7 -0.81 8.214949E7 -1.74E7 -0.94 -1.2345 -0.9974 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M07 compound treatment 9.0031431E7 -1620000.0 -0.08 9.6831787E7 -2700000.0 -0.15 -0.1617 -0.9646 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M08 compound treatment 9.7996452E7 6340000.0 0.33 1.02499293E8 2960000.0 0.16 0.3427 0.9463 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M09 mock treatment 9.029085E7 -1360000.0 -0.07 9.5281995E7 -4250000.0 -0.23 -0.2113 -0.8825 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M10 mock treatment 8.779088E7 -3860000.0 -0.2 9.8809007E7 -727000.0 -0.04 -0.1676 -0.8309 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M11 compound treatment 8.4836576E7 -6820000.0 -0.35 9.7250885E7 -2290000.0 -0.12 -0.334 -0.9019 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M12 compound treatment 8.8661473E7 -2990000.0 -0.15 1.01737378E8 2200000.0 0.12 -0.0246 -0.1268 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M13 mock treatment 8.5748188E7 -5900000.0 -0.3 9.8361392E7 -1170000.0 -0.06 -0.2587 -0.8368 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M14 mock treatment 9.0705534E7 -947000.0 -0.05 9.5060778E7 -4480000.0 -0.24 -0.2047 -0.8328 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M15 compound treatment 8.5178185E7 -6470000.0 -0.33 9.1231969E7 -8300000.0 -0.45 -0.5508 -0.9892 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M16 compound treatment 8.7012716E7 -4640000.0 -0.24 9.1658695E7 -7880000.0 -0.42 -0.4681 -0.9626 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M17 compound treatment 8.7742044E7 -3910000.0 -0.2 9.542044E7 -4120000.0 -0.22 -0.2984 -0.9987 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M18 compound treatment 9.2472559E7 820000.0 0.04 1.00333886E8 798000.0 0.04 0.0601 0.9999 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M19 mock treatment 9.0582598E7 -1070000.0 -0.05 9.53937E7 -4140000.0 -0.22 -0.1965 -0.8555 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M20 compound treatment 7.8122056E7 -1.35E7 -0.69 8.213616E7 -1.74E7 -0.94 -1.1529 -0.989 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M21 mock treatment 1.02884208E8 1.12E7 0.58 1.08808473E8 9270000.0 0.5 0.7601 0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M22 compound treatment 9.3481669E7 1830000.0 0.09 9.9200534E7 -336000.0 -0.02 0.0535 0.5605 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M23 mock treatment 1.05627383E8 1.4E7 0.72 1.11058975E8 1.15E7 0.62 0.9452 0.9974 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 M24 compound treatment 9.7680188E7 6030000.0 0.31 9.527E7 -4270000.0 -0.23 0.056 0.1455 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N01 compound treatment 1.07525151E8 1.59E7 0.81 1.12102371E8 1.26E7 0.68 1.0537 0.9958 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N02 compound treatment 7.7291112E7 -1.44E7 -0.74 7.7020116E7 -2.25E7 -1.21 -1.3778 -0.9714 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N03 compound treatment 9.7326779E7 5670000.0 0.29 1.02371017E8 2830000.0 0.15 0.3136 0.9547 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N04 compound treatment 1.02366018E8 1.07E7 0.55 1.02276172E8 2740000.0 0.15 0.4926 0.8664 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N05 compound treatment 8.7994267E7 -3660000.0 -0.19 1.00339536E8 803000.0 0.04 -0.102 -0.53 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N06 compound treatment 8.9782646E7 -1870000.0 -0.1 9.13068E7 -8230000.0 -0.44 -0.3811 -0.8406 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N07 compound treatment 9.1536613E7 -116000.0 -0.01 9.5955545E7 -3580000.0 -0.19 -0.1405 -0.7285 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N08 compound treatment 7.8668293E7 -1.3E7 -0.67 8.7062826E7 -1.25E7 -0.67 -0.9455 -1.0 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N09 mock treatment 8.7530062E7 -4120000.0 -0.21 1.013119E8 1780000.0 0.1 -0.0818 -0.3526 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N10 mock treatment 8.6325158E7 -5330000.0 -0.27 9.5195118E7 -4340000.0 -0.23 -0.3584 -0.997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N11 compound treatment 8.758908E7 -4060000.0 -0.21 9.4963974E7 -4570000.0 -0.25 -0.3214 -0.9965 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N12 compound treatment 7.8355501E7 -1.33E7 -0.68 8.0120552E7 -1.94E7 -1.05 -1.2212 -0.9785 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N13 mock treatment 8.7458459E7 -4190000.0 -0.21 1.0186947E8 2330000.0 0.13 -0.0631 -0.2536 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N14 mock treatment 8.615923E7 -5490000.0 -0.28 9.9686807E7 151000.0 0.01 -0.1933 -0.6864 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N15 compound treatment 8.8159431E7 -3490000.0 -0.18 1.00625789E8 1090000.0 0.06 -0.0851 -0.4517 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N16 compound treatment 8.867161E7 -2980000.0 -0.15 9.8628818E7 -907000.0 -0.05 -0.1426 -0.8889 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N17 compound treatment 9.4840814E7 3190000.0 0.16 1.03718592E8 4180000.0 0.23 0.2748 0.9876 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N18 compound treatment 8.2806232E7 -8850000.0 -0.45 7.7252709E7 -2.23E7 -1.2 -1.1691 -0.9114 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N19 compound treatment 9.1065762E7 -587000.0 -0.03 9.4592622E7 -4940000.0 -0.27 -0.2095 -0.782 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N20 compound treatment 8.4387833E7 -7260000.0 -0.37 8.2321832E7 -1.72E7 -0.93 -0.9188 -0.9197 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N21 compound treatment 9.6923853E7 5270000.0 0.27 9.9444658E7 -91500.0 0.0 0.1876 0.6941 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N22 compound treatment 9.5655057E7 4000000.0 0.21 9.0565671E7 -8970000.0 -0.48 -0.1965 -0.3745 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N23 compound treatment 9.6281199E7 4630000.0 0.24 1.0231778E8 2780000.0 0.15 0.2737 0.9754 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 N24 compound treatment 1.00093595E8 8440000.0 0.43 9.7729125E7 -1810000.0 -0.1 0.2371 0.5347 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O01 mock treatment 1.10730997E8 1.91E7 0.98 1.14428293E8 1.49E7 0.8 1.2585 0.9952 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O02 compound treatment 9.3651574E7 2000000.0 0.1 9.5466522E7 -4070000.0 -0.22 -0.0825 -0.3411 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O03 mock treatment 9.9379749E7 7730000.0 0.4 1.01067945E8 1530000.0 0.08 0.3384 0.8364 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O04 mock treatment 9.5219963E7 3570000.0 0.18 1.06997688E8 7460000.0 0.4 0.4134 0.9365 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O05 mock treatment 9.5965479E7 4310000.0 0.22 9.8950286E7 -586000.0 -0.03 0.134 0.6001 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O06 mock treatment 9.3092127E7 1440000.0 0.07 9.8379254E7 -1160000.0 -0.06 0.0081 0.0841 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O07 mock treatment 9.0062448E7 -1590000.0 -0.08 9.4765859E7 -4770000.0 -0.26 -0.2393 -0.8878 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O08 mock treatment 8.9037029E7 -2620000.0 -0.13 8.888298E7 -1.07E7 -0.57 -0.5004 -0.8495 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O09 mock treatment 9.1855357E7 203000.0 0.01 1.03463955E8 3930000.0 0.21 0.1569 0.741 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O10 mock treatment 8.8201484E7 -3450000.0 -0.18 9.590682E7 -3630000.0 -0.2 -0.2633 -0.9988 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O11 mock treatment 9.1695916E7 43400.0 0.0 9.4194419E7 -5340000.0 -0.29 -0.2018 -0.7016 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O12 mock treatment 9.7688238E7 6040000.0 0.31 1.02790032E8 3250000.0 0.18 0.3426 0.9638 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O13 mock treatment 8.4783023E7 -6870000.0 -0.35 9.9510272E7 -25900.0 0.0 -0.2499 -0.7099 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O14 mock treatment 9.3027568E7 1380000.0 0.07 1.07117081E8 7580000.0 0.41 0.3385 0.8171 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O15 mock treatment 9.0845003E7 -808000.0 -0.04 1.00429992E8 894000.0 0.05 0.0048 0.0752 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O16 mock treatment 9.0434764E7 -1220000.0 -0.06 9.9637815E7 102000.0 0.01 -0.0403 -0.6426 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O17 mock treatment 8.9815785E7 -1840000.0 -0.09 1.07549056E8 8010000.0 0.43 0.2386 0.5401 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O18 mock treatment 9.5810967E7 4160000.0 0.21 1.04364194E8 4830000.0 0.26 0.3346 0.9951 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O19 mock treatment 9.4436255E7 2780000.0 0.14 9.2182332E7 -7350000.0 -0.4 -0.1791 -0.4256 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O20 mock treatment 9.4899094E7 3250000.0 0.17 8.9296734E7 -1.02E7 -0.55 -0.2722 -0.4727 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O21 mock treatment 1.09384326E8 1.77E7 0.91 1.11606717E8 1.21E7 0.65 1.1022 0.9865 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O22 mock treatment 9.9920224E7 8270000.0 0.42 1.0219941E8 2660000.0 0.14 0.401 0.8965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O23 mock treatment 1.05253191E8 1.36E7 0.7 1.03600451E8 4060000.0 0.22 0.6477 0.8865 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 O24 mock treatment 1.15750735E8 2.41E7 1.24 1.17130076E8 1.76E7 0.95 1.5433 0.9914 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P01 compound treatment 1.14466166E8 2.28E7 1.17 1.18216479E8 1.87E7 1.01 1.5381 0.9972 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P02 compound treatment 1.05599723E8 1.39E7 0.71 1.12257823E8 1.27E7 0.69 0.9899 0.9998 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P03 compound treatment 9.874178E7 7090000.0 0.36 1.02093869E8 2560000.0 0.14 0.3543 0.9118 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P04 compound treatment 7.0271837E7 -2.14E7 -1.1 9.1089718E7 -8450000.0 -0.45 -1.0965 -0.9242 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P05 compound treatment 9.2375958E7 723000.0 0.04 9.6913974E7 -2620000.0 -0.14 -0.0736 -0.5043 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P06 compound treatment 1.04831442E8 1.32E7 0.68 1.10465861E8 1.09E7 0.59 0.8938 0.9976 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P07 compound treatment 9.5503252E7 3850000.0 0.2 1.03270555E8 3730000.0 0.2 0.2818 1.0 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P08 compound treatment 9.2624445E7 972000.0 0.05 9.595594E7 -3580000.0 -0.19 -0.1011 -0.5077 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P09 compound treatment 9.2462157E7 810000.0 0.04 1.04411866E8 4880000.0 0.26 0.215 0.8088 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P10 compound treatment 9.4241975E7 2590000.0 0.13 9.2596811E7 -6940000.0 -0.37 -0.1704 -0.4297 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P11 mock treatment 9.2602912E7 950000.0 0.05 9.8838552E7 -698000.0 -0.04 0.0079 0.1281 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P12 mock treatment 1.00314295E8 8660000.0 0.44 1.06580556E8 7040000.0 0.38 0.5822 0.9969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P13 compound treatment 9.2832775E7 1180000.0 0.06 9.9045978E7 -490000.0 -0.03 0.0241 0.3653 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P14 compound treatment 8.2222316E7 -9430000.0 -0.48 6.8753855E7 -3.08E7 -1.66 -1.5139 -0.8768 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P15 compound treatment 9.8103543E7 6450000.0 0.33 9.4379153E7 -5160000.0 -0.28 0.0374 0.0867 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P16 compound treatment 9.7742283E7 6090000.0 0.31 9.1579597E7 -7960000.0 -0.43 -0.0823 -0.1552 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P17 compound treatment 1.02816565E8 1.12E7 0.57 9.9843909E7 308000.0 0.02 0.4163 0.7273 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P18 compound treatment 9.8388133E7 6740000.0 0.35 9.0283745E7 -9250000.0 -0.5 -0.1082 -0.1785 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P19 compound treatment 1.03674327E8 1.2E7 0.62 9.7332702E7 -2200000.0 -0.12 0.3518 0.5606 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P20 compound treatment 7.9503673E7 -1.21E7 -0.62 6.9027881E7 -3.05E7 -1.64 -1.602 -0.9118 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P21 compound treatment 1.03041416E8 1.14E7 0.58 1.02428788E8 2890000.0 0.16 0.5229 0.8655 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P22 compound treatment 8.785062E7 -3800000.0 -0.19 7.9197068E7 -2.03E7 -1.1 -0.9123 -0.82 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P23 compound treatment 1.13648158E8 2.2E7 1.13 1.20367386E8 2.08E7 1.12 1.5904 1.0 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2130 P24 compound treatment 1.08334719E8 1.67E7 0.86 1.12421113E8 1.29E7 0.69 1.0952 0.9946 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A01 compound treatment 1.28676976E8 3.09E7 1.59 1.1722161E8 2.65E7 1.43 2.1304 0.9986 3237406 Sulf1.1-A_000001 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A02 compound treatment 1.24344359E8 2.66E7 1.36 1.15963894E8 2.52E7 1.36 1.9255 1.0 3237380 Sulf1.1-A_000002 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3ccc(Cl)cc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A03 compound treatment 1.09574999E8 1.18E7 0.61 9.1283927E7 567000.0 0.03 0.4505 0.7418 3237177 Sulf1.1-A_000003 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc(cc3)c4ccccc4)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A04 compound treatment 1.35999891E8 3.83E7 1.96 1.24768677E8 3.41E7 1.83 2.6832 0.9994 3237394 Sulf1.1-A_000004 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A05 compound treatment 9.5705377E7 -2040000.0 -0.1 7.57229E7 -1.5E7 -0.81 -0.6447 -0.7919 3237332 Sulf1.1-A_000005 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A06 compound treatment 1.21680351E8 2.39E7 1.23 1.02393145E8 1.17E7 0.63 1.3122 0.9518 3237396 Sulf1.1-A_000006 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc(Cl)cc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A07 compound treatment 1.18695881E8 2.1E7 1.07 9.8732809E7 8020000.0 0.43 1.0647 0.9198 3237257 Sulf1.1-A_000007 Cc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A08 compound treatment 1.14733742E8 1.7E7 0.87 1.02985279E8 1.23E7 0.66 1.083 0.9907 3237153 Sulf1.1-A_000008 OCCOc1ccc(CN2CC[C@@H](C2)N3C(=O)c4ccccc4C3=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A09 compound treatment 7.6724222E7 -2.1E7 -1.08 4.7010019E7 -4.37E7 -2.35 -2.4259 -0.9372 3237428 Sulf1.1-A_000009 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A10 compound treatment 5.9030984E7 -3.87E7 -1.98 3.8808243E7 -5.19E7 -2.8 -3.3795 -0.9859 3237318 Sulf1.1-A_000010 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3cccc4cccnc34)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A11 compound treatment 1.1743719E8 1.97E7 1.01 1.02726773E8 1.2E7 0.65 1.1711 0.9768 3237197 Sulf1.1-A_000011 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A12 compound treatment 1.15336549E8 1.76E7 0.9 9.6585308E7 5870000.0 0.32 0.8611 0.9012 3237446 Sulf1.1-A_000012 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A13 mock treatment 1.14479819E8 1.67E7 0.86 1.05107895E8 1.44E7 0.77 1.1546 0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A14 mock treatment 1.0956806E8 1.18E7 0.61 9.2777702E7 2060000.0 0.11 0.5071 0.8229 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A15 compound treatment 1.05233968E8 7490000.0 0.38 8.5884431E7 -4830000.0 -0.26 0.0875 0.1887 3237240 Sulf1.1-A_000013 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3cccc(F)c3)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A16 compound treatment 1.13986996E8 1.62E7 0.83 9.8124426E7 7410000.0 0.4 0.8708 0.9432 3237246 Sulf1.1-A_000014 COc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A17 compound treatment 8.0148067E7 -1.76E7 -0.9 6.1775704E7 -2.89E7 -1.56 -1.7396 -0.9662 3237241 Sulf1.1-A_000015 CC(C)S(=O)(=O)NCC1CCN(Cc2ccc(OCCO)cc2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A18 compound treatment 1.30117855E8 3.24E7 1.66 1.1745454E8 2.67E7 1.44 2.1915 0.9975 3237449 Sulf1.1-A_000016 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A19 compound treatment 9.3258995E7 -4480000.0 -0.23 8.9457837E7 -1260000.0 -0.07 -0.2104 -0.8783 3237371 Sulf1.1-A_000017 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3cccc4cccnc34)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A20 compound treatment 8.3178946E7 -1.46E7 -0.75 6.4252023E7 -2.65E7 -1.43 -1.5355 -0.9545 3237416 Sulf1.1-A_000018 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cccc(F)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A21 compound treatment 1.08046033E8 1.03E7 0.53 1.02295081E8 1.16E7 0.62 0.8144 0.9966 3237365 Sulf1.1-A_000019 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3ccc(Cl)cc3)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A22 compound treatment 1.18466803E8 2.07E7 1.06 1.16773398E8 2.61E7 1.4 1.7433 0.9906 3237151 Sulf1.1-A_000020 OCCOc1ccc(CN2CC[C@H](C2)N3C(=O)c4ccccc4C3=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A23 compound treatment 1.23668768E8 2.59E7 1.33 1.13496202E8 2.28E7 1.23 1.8071 0.9992 3237460 Sulf1.1-A_000021 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3ccc(cc3)c4ccccc4)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 A24 compound treatment 1.29859067E8 3.21E7 1.65 1.31610655E8 4.09E7 2.2 2.7212 0.9897 3237391 Sulf1.1-A_000022 CC(C)S(=O)(=O)NC1CCN(Cc2cccc(OCCO)c2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B01 compound treatment 1.13675696E8 1.59E7 0.82 1.05880351E8 1.52E7 0.82 1.1549 1.0 3237454 Sulf1.1-A_000023 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B02 mock treatment 1.11592839E8 1.39E7 0.71 1.02639461E8 1.19E7 0.64 0.956 0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B03 compound treatment 1.04267787E8 6530000.0 0.33 8.2278959E7 -8440000.0 -0.45 -0.0848 -0.1502 3237356 Sulf1.1-A_000024 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cccc(F)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B04 mock treatment 1.05865394E8 8120000.0 0.42 9.460448E7 3890000.0 0.21 0.4425 0.9494 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B05 compound treatment 9.8383977E7 643000.0 0.03 8.4691016E7 -6030000.0 -0.32 -0.2061 -0.632 3237374 Sulf1.1-A_000025 Cc1nc(cn1C)S(=O)(=O)NCC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B06 mock treatment 1.04345301E8 6600000.0 0.34 9.0031166E7 -685000.0 -0.04 0.2132 0.6263 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B07 compound treatment 9.9901895E7 2160000.0 0.11 9.755929E7 6840000.0 0.37 0.3389 0.8807 3237437 Sulf1.1-A_000026 Cc1ccc(cc1)S(=O)(=O)N[C@@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B08 mock treatment 1.03652396E8 5910000.0 0.3 8.9858398E7 -858000.0 -0.05 0.1816 0.5924 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B09 compound treatment 1.04558481E8 6820000.0 0.35 9.4362873E7 3650000.0 0.2 0.3859 0.9629 3237320 Sulf1.1-A_000027 Cc1ccccc1S(=O)(=O)NC[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B10 mock treatment 1.00133156E8 2390000.0 0.12 8.5345567E7 -5370000.0 -0.29 -0.1178 -0.3751 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B11 compound treatment 8.7746322E7 -9990000.0 -0.51 6.25576E7 -2.82E7 -1.52 -1.4345 -0.8962 3237427 Sulf1.1-A_000028 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B12 mock treatment 1.02543521E8 4800000.0 0.25 9.5126533E7 4410000.0 0.24 0.342 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B13 mock treatment 1.04858052E8 7120000.0 0.36 8.8337631E7 -2380000.0 -0.13 0.1673 0.4328 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B14 mock treatment 1.04866992E8 7130000.0 0.37 8.8339155E7 -2380000.0 -0.13 0.1677 0.4334 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B15 compound treatment 1.07163729E8 9420000.0 0.48 9.1443021E7 726000.0 0.04 0.3691 0.7619 3237372 Sulf1.1-A_000029 Cc1ccccc1S(=O)(=O)NCC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B16 mock treatment 1.03792348E8 6050000.0 0.31 8.9293468E7 -1420000.0 -0.08 0.1651 0.5168 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B17 compound treatment 1.07431873E8 9690000.0 0.5 9.0817078E7 100000.0 0.01 0.355 0.7148 3237289 Sulf1.1-A_000030 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B18 mock treatment 1.04571657E8 6830000.0 0.35 9.1663366E7 947000.0 0.05 0.2836 0.8016 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B19 compound treatment 8.0421706E7 -1.73E7 -0.89 5.2267837E7 -3.84E7 -2.07 -2.0917 -0.9285 3237235 Sulf1.1-A_000031 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3ccc(Cl)c(Cl)c3)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B20 mock treatment 1.21733224E8 2.4E7 1.23 1.10782447E8 2.01E7 1.08 1.6336 0.9979 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B21 compound treatment 1.06215909E8 8470000.0 0.43 9.6688803E7 5970000.0 0.32 0.5345 0.9891 3237435 Sulf1.1-A_000032 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3cccc(F)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B22 mock treatment 1.09757083E8 1.2E7 0.62 1.04936922E8 1.42E7 0.77 0.977 0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B23 compound treatment 1.16924165E8 1.92E7 0.98 1.06624779E8 1.59E7 0.86 1.301 0.9976 3237254 Sulf1.1-A_000033 Cc1nc(cn1C)S(=O)(=O)NC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 B24 mock treatment 1.31638417E8 3.39E7 1.74 1.1312219E8 2.24E7 1.21 2.0816 0.9841 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C01 compound treatment 1.21535218E8 2.38E7 1.22 1.06535338E8 1.58E7 0.85 1.4647 0.9846 3237301 Sulf1.1-A_000034 CC(C)S(=O)(=O)N[C@@H]1CCN(Cc2ccc(OCCO)cc2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C02 compound treatment 1.09146599E8 1.14E7 0.58 9.3272572E7 2560000.0 0.14 0.5107 0.8503 3237158 Sulf1.1-A_000035 OCCOc1ccc(CN2CCC[C@@H](CN3C(=O)c4ccccc4C3=O)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C03 compound treatment 9.5532278E7 -2210000.0 -0.11 8.7348009E7 -3370000.0 -0.18 -0.2083 -0.9742 3237256 Sulf1.1-A_000036 CC(C)S(=O)(=O)NC1CCN(Cc2ccc(OCCO)cc2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C04 compound treatment 6.0888943E7 -3.69E7 -1.89 3.0798376E7 -5.99E7 -3.23 -3.6171 -0.9675 3237156 Sulf1.1-A_000037 OCCOc1ccc(CN2CCC[C@H](C2)N3C(=O)c4ccccc4C3=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C05 compound treatment 7.7604279E7 -2.01E7 -1.03 6.9497217E7 -2.12E7 -1.14 -1.5378 -0.9987 3237312 Sulf1.1-A_000038 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc(cc3)c4ccccc4)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C06 compound treatment 9.9984871E7 2240000.0 0.12 9.2783203E7 2070000.0 0.11 0.16 0.9999 3237455 Sulf1.1-A_000039 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C07 compound treatment 5.556108E7 -4.22E7 -2.16 4.2838272E7 -4.79E7 -2.58 -3.3518 -0.9962 3237443 Sulf1.1-A_000040 Cc1ccc(F)cc1S(=O)(=O)N2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C08 compound treatment 7.8089982E7 -1.97E7 -1.01 6.9700377E7 -2.1E7 -1.13 -1.5124 -0.9983 3237464 Sulf1.1-A_000041 Cc1ccccc1S(=O)(=O)N2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C09 compound treatment 1.0391746E8 6180000.0 0.32 9.2189658E7 1470000.0 0.08 0.2799 0.8578 3237452 Sulf1.1-A_000042 CC(C)S(=O)(=O)N1CCN(Cc2ccc(OCCO)cc2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C10 compound treatment 9.2195859E7 -5550000.0 -0.28 8.2631433E7 -8090000.0 -0.44 -0.5088 -0.9786 3237191 Sulf1.1-A_000043 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3cccc(F)c3)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C11 mock treatment 9.2676779E7 -5060000.0 -0.26 9.1462676E7 746000.0 0.04 -0.1551 -0.5906 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C12 mock treatment 8.9989594E7 -7750000.0 -0.4 9.0225332E7 -491000.0 -0.03 -0.2996 -0.7525 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C13 compound treatment 9.3513627E7 -4230000.0 -0.22 9.8904281E7 8190000.0 0.44 0.1586 0.3228 3237189 Sulf1.1-A_000044 Cc1nc(cn1C)S(=O)(=O)NC[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C14 compound treatment 9.4484734E7 -3260000.0 -0.17 8.5098042E7 -5620000.0 -0.3 -0.332 -0.9607 3237360 Sulf1.1-A_000045 Cc1ccc(cc1)S(=O)(=O)N[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C15 mock treatment 9.0100287E7 -7640000.0 -0.39 7.6735544E7 -1.4E7 -0.75 -0.8093 -0.9536 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C16 mock treatment 8.7828743E7 -9910000.0 -0.51 7.3396569E7 -1.73E7 -0.93 -1.0188 -0.9592 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C17 compound treatment 1.14648062E8 1.69E7 0.87 1.03037006E8 1.23E7 0.66 1.0819 0.9913 3237358 Sulf1.1-A_000046 CC(C)S(=O)(=O)N[C@@H]1CCCN(Cc2cccc(OCCO)c2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C18 compound treatment 8.6662962E7 -1.11E7 -0.57 7.4648419E7 -1.61E7 -0.87 -1.0133 -0.9791 3237390 Sulf1.1-A_000047 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3cccc(F)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C19 compound treatment 6.0376159E7 -3.74E7 -1.92 4.809708E7 -4.26E7 -2.3 -2.977 -0.996 3237243 Sulf1.1-A_000048 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C20 compound treatment 1.00819623E8 3080000.0 0.16 9.2042099E7 1330000.0 0.07 0.162 0.9357 3237467 Sulf1.1-A_000049 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3cccc(F)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C21 compound treatment 1.10102824E8 1.24E7 0.63 1.02826814E8 1.21E7 0.65 0.9091 0.9999 3237185 Sulf1.1-A_000050 Cc1ccccc1S(=O)(=O)NC[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C22 compound treatment 1.03924061E8 6180000.0 0.32 9.6893853E7 6180000.0 0.33 0.4593 0.9997 3237163 Sulf1.1-A_000051 OCCOc1cccc(CN2CCC(CC2)N3C(=O)c4ccccc4C3=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C23 compound treatment 1.06862178E8 9120000.0 0.47 1.02295876E8 1.16E7 0.62 0.7715 0.9899 3237285 Sulf1.1-A_000052 Cc1ccc(cc1)S(=O)(=O)N[C@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 C24 compound treatment 1.09186864E8 1.14E7 0.59 1.04323997E8 1.36E7 0.73 0.933 0.9939 3237265 Sulf1.1-A_000053 Cc1ccc(F)cc1S(=O)(=O)N[C@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D01 compound treatment 5.1245147E7 -4.65E7 -2.38 4.22956E7 -4.84E7 -2.61 -3.5289 -0.999 3237408 Sulf1.1-A_000054 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cccc4cccnc34)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D02 mock treatment 1.01635464E8 3890000.0 0.2 9.261107E7 1890000.0 0.1 0.2133 0.9514 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D03 compound treatment 5.5792645E7 -4.19E7 -2.15 5.2111168E7 -3.86E7 -2.08 -2.9903 -0.9999 3237375 Sulf1.1-A_000055 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3cccc(F)c3)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D04 mock treatment 9.582897E7 -1910000.0 -0.1 9.016073E7 -556000.0 -0.03 -0.0905 -0.8828 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D05 compound treatment 8.8570256E7 -9170000.0 -0.47 8.7938365E7 -2780000.0 -0.15 -0.4382 -0.8883 3237458 Sulf1.1-A_000056 COc1ccc(cc1)S(=O)(=O)N2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D06 mock treatment 1.01713962E8 3970000.0 0.2 9.4265108E7 3550000.0 0.19 0.2791 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D07 compound treatment 8.1594933E7 -1.61E7 -0.83 7.8530297E7 -1.22E7 -0.66 -1.0492 -0.9934 3237247 Sulf1.1-A_000057 Cc1ccc(F)cc1S(=O)(=O)NC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D08 mock treatment 9.555078E7 -2190000.0 -0.11 9.400326E7 3290000.0 0.18 0.0458 0.2184 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D09 compound treatment 8.9924192E7 -7820000.0 -0.4 9.0448026E7 -269000.0 -0.01 -0.2935 -0.7322 3237279 Sulf1.1-A_000058 Cc1nc(cn1C)S(=O)(=O)N[C@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D10 mock treatment 9.1026606E7 -6710000.0 -0.34 9.2740227E7 2020000.0 0.11 -0.1663 -0.4606 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D11 mock treatment 8.9884423E7 -7860000.0 -0.4 8.8046601E7 -2670000.0 -0.14 -0.3864 -0.9037 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D12 mock treatment 1.04657934E8 6920000.0 0.35 9.9784766E7 9070000.0 0.49 0.596 0.9876 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D13 compound treatment 7.8437547E7 -1.93E7 -0.99 7.2999061E7 -1.77E7 -0.95 -1.3742 -0.9998 3237383 Sulf1.1-A_000059 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D14 mock treatment 9.1102651E7 -6640000.0 -0.34 9.0614408E7 -102000.0 -0.01 -0.2445 -0.7185 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D15 mock treatment 9.6531168E7 -1210000.0 -0.06 9.3812507E7 3100000.0 0.17 0.074 0.4162 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D16 mock treatment 1.0863854E8 1.09E7 0.56 9.6449757E7 5730000.0 0.31 0.6132 0.9609 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D17 compound treatment 3.3110826E7 -6.46E7 -3.31 2.7915844E7 -6.28E7 -3.38 -4.7336 -0.9999 3237175 Sulf1.1-A_000060 Cc1ccc(F)cc1S(=O)(=O)NC[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D18 mock treatment 1.06692753E8 8950000.0 0.46 9.6496743E7 5780000.0 0.31 0.5445 0.9821 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D19 compound treatment 8.1209292E7 -1.65E7 -0.85 8.8594067E7 -2120000.0 -0.11 -0.68 -0.7953 3237205 Sulf1.1-A_000061 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D20 mock treatment 1.01524141E8 3780000.0 0.19 1.00141162E8 9420000.0 0.51 0.496 0.9129 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D21 compound treatment 6.1182237E7 -3.66E7 -1.87 5.6151261E7 -3.46E7 -1.86 -2.6411 -1.0 3237238 Sulf1.1-A_000062 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3ccc4ccccc4c3)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D22 mock treatment 1.07475347E8 9730000.0 0.5 1.04026255E8 1.33E7 0.72 0.8596 0.9843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D23 compound treatment 9.5132283E7 -2610000.0 -0.13 9.2584779E7 1870000.0 0.1 -0.0234 -0.1399 3237342 Sulf1.1-A_000063 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 D24 mock treatment 1.2557386E8 2.78E7 1.43 1.18106191E8 2.74E7 1.47 2.0516 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E01 mock treatment 1.04250255E8 6510000.0 0.33 8.8863644E7 -1850000.0 -0.1 0.1653 0.4748 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E02 mock treatment 8.566508E7 -1.21E7 -0.62 7.7164309E7 -1.36E7 -0.73 -0.9537 -0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E03 compound treatment 1.10544285E8 1.28E7 0.66 1.0050027E8 9780000.0 0.53 0.8365 0.9941 3237456 Sulf1.1-A_000064 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E04 compound treatment 7.2254858E7 -2.55E7 -1.31 6.5198226E7 -2.55E7 -1.37 -1.8953 -0.9997 3237281 Sulf1.1-A_000065 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cccc(F)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E05 compound treatment 6.5515085E7 -3.22E7 -1.65 7.0959246E7 -1.98E7 -1.06 -1.9202 -0.9774 3237430 Sulf1.1-A_000066 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E06 compound treatment 1.0698096E8 9240000.0 0.47 9.7259823E7 6540000.0 0.35 0.584 0.9894 3237248 Sulf1.1-A_000067 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E07 compound treatment 8.9134802E7 -8610000.0 -0.44 9.245403E7 1740000.0 0.09 -0.2457 -0.545 3237392 Sulf1.1-A_000068 Cc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E08 compound treatment 1.02210542E8 4470000.0 0.23 9.4501958E7 3790000.0 0.2 0.3061 0.9983 3237369 Sulf1.1-A_000069 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E09 mock treatment 8.7796498E7 -9940000.0 -0.51 7.9321101E7 -1.14E7 -0.61 -0.7943 -0.9957 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E10 mock treatment 9.2784455E7 -4960000.0 -0.25 8.3073203E7 -7640000.0 -0.41 -0.4707 -0.9731 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E11 compound treatment 6.2133659E7 -3.56E7 -1.82 6.3608682E7 -2.71E7 -1.46 -2.3227 -0.9939 3237294 Sulf1.1-A_000070 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(Cl)ccc3Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E12 compound treatment 9.8551768E7 811000.0 0.04 9.2836901E7 2120000.0 0.11 0.1101 0.9063 3237436 Sulf1.1-A_000071 CC(C)S(=O)(=O)N[C@@H]1CCN(Cc2cccc(OCCO)c2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E13 compound treatment 8.0876452E7 -1.69E7 -0.86 6.3890272E7 -2.68E7 -1.44 -1.6327 -0.9698 3237379 Sulf1.1-A_000072 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E14 compound treatment 1.01393526E8 3650000.0 0.19 9.5456771E7 4740000.0 0.26 0.3129 0.9884 3237253 Sulf1.1-A_000073 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3ccc4ccccc4c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E15 compound treatment 9.4251146E7 -3490000.0 -0.18 9.8126742E7 7410000.0 0.4 0.1557 0.356 3237322 Sulf1.1-A_000074 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc4ccccc4c3)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E16 compound treatment 3.5290052E7 -6.25E7 -3.2 5.3585702E7 -3.71E7 -2.0 -3.6772 -0.9743 3237219 Sulf1.1-A_000075 Cc1nc(cn1C)S(=O)(=O)N[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E17 mock treatment 8.6741325E7 -1.1E7 -0.56 7.8920431E7 -1.18E7 -0.64 -0.8478 -0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E18 mock treatment 1.0041288E8 2670000.0 0.14 8.9379551E7 -1340000.0 -0.07 0.0459 0.2968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E19 compound treatment 6.4363887E7 -3.34E7 -1.71 6.0419504E7 -3.03E7 -1.63 -2.3633 -0.9997 3237298 Sulf1.1-A_000076 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc4ccccc4c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E20 compound treatment 8.7769033E7 -9970000.0 -0.51 9.1548234E7 832000.0 0.04 -0.3297 -0.6427 3237439 Sulf1.1-A_000077 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3ccccc3[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E21 compound treatment 9.8308639E7 568000.0 0.03 1.03883661E8 1.32E7 0.71 0.5219 0.7355 3237225 Sulf1.1-A_000078 Cc1ccc(cc1)S(=O)(=O)N[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E22 compound treatment 1.08224208E8 1.05E7 0.54 1.04089779E8 1.34E7 0.72 0.8891 0.9896 3237306 Sulf1.1-A_000079 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc(Cl)cc3)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E23 compound treatment 9.0728589E7 -7010000.0 -0.36 8.569179E7 -5020000.0 -0.27 -0.4455 -0.9902 3237420 Sulf1.1-A_000080 Cc1ccc(cc1)S(=O)(=O)N[C@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 E24 compound treatment 1.09150226E8 1.14E7 0.58 1.10212444E8 1.95E7 1.05 1.1558 0.9618 3237469 Sulf1.1-A_000081 Cc1ccc(cc1)S(=O)(=O)N2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F01 mock treatment 1.18018397E8 2.03E7 1.04 1.09110982E8 1.84E7 0.99 1.4353 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F02 mock treatment 1.15051896E8 1.73E7 0.89 1.07085713E8 1.64E7 0.88 1.2507 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F03 compound treatment 6.1348065E7 -3.64E7 -1.87 5.9962055E7 -3.08E7 -1.66 -2.49 -0.9982 3237364 Sulf1.1-A_000082 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3ccccc3)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F04 mock treatment 1.05761444E8 8020000.0 0.41 9.4446001E7 3730000.0 0.2 0.4327 0.9457 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F05 compound treatment 6.9503182E7 -2.82E7 -1.45 7.088174E7 -1.98E7 -1.07 -1.7786 -0.9888 3237352 Sulf1.1-A_000083 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc4ccccc4c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F06 mock treatment 9.7869838E7 129000.0 0.01 9.2020323E7 1300000.0 0.07 0.0543 0.7702 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F07 compound treatment 9.8789607E7 1050000.0 0.05 9.1542909E7 826000.0 0.04 0.0695 0.9956 3237271 Sulf1.1-A_000084 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F08 mock treatment 9.1391994E7 -6350000.0 -0.33 9.1227135E7 511000.0 0.03 -0.2107 -0.6451 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F09 mock treatment 9.7981881E7 241000.0 0.01 9.0600517E7 -116000.0 -0.01 0.0043 0.3113 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F10 mock treatment 9.2241612E7 -5500000.0 -0.28 9.0646394E7 -70200.0 0.0 -0.202 -0.7165 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F11 compound treatment 9.5202291E7 -2540000.0 -0.13 8.7821356E7 -2900000.0 -0.16 -0.2023 -0.996 3237444 Sulf1.1-A_000085 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3ccc(cc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F12 mock treatment 9.8385778E7 645000.0 0.03 9.309956E7 2380000.0 0.13 0.1141 0.8611 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F13 compound treatment 8.6653819E7 -1.11E7 -0.57 7.7710373E7 -1.3E7 -0.7 -0.8971 -0.9946 3237438 Sulf1.1-A_000086 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F14 mock treatment 1.02100924E8 4360000.0 0.22 9.3997428E7 3280000.0 0.18 0.2829 0.9932 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F15 compound treatment 8.1094654E7 -1.66E7 -0.85 8.297119E7 -7750000.0 -0.42 -0.8982 -0.9458 3237422 Sulf1.1-A_000087 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F16 mock treatment 9.5673063E7 -2070000.0 -0.11 9.3607492E7 2890000.0 0.16 0.0351 0.1866 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F17 mock treatment 9.6465302E7 -1280000.0 -0.07 9.4084444E7 3370000.0 0.18 0.082 0.4254 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F18 mock treatment 1.05482875E8 7740000.0 0.4 9.9296148E7 8580000.0 0.46 0.6073 0.9971 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F19 compound treatment 1.05740029E8 8000000.0 0.41 1.01893516E8 1.12E7 0.6 0.7155 0.9825 3237453 Sulf1.1-A_000088 Cc1ccc(cc1)S(=O)(=O)N2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F20 mock treatment 1.13310143E8 1.56E7 0.8 1.06005487E8 1.53E7 0.82 1.1464 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F21 compound treatment 1.04142988E8 6400000.0 0.33 1.01253269E8 1.05E7 0.57 0.6332 0.9661 3237203 Sulf1.1-A_000089 COc1ccc(cc1)S(=O)(=O)N[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F22 mock treatment 1.12972791E8 1.52E7 0.78 1.0418456E8 1.35E7 0.73 1.0649 0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F23 compound treatment 6.4912793E7 -3.28E7 -1.68 6.1798734E7 -2.89E7 -1.56 -2.2909 -0.9993 3237326 Sulf1.1-A_000090 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3cccc(F)c3)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 F24 mock treatment 1.27574377E8 2.98E7 1.53 1.24239579E8 3.35E7 1.81 2.3577 0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G01 compound treatment 5.5367097E7 -4.24E7 -2.17 4.3679196E7 -4.7E7 -2.53 -3.3268 -0.9971 3237230 Sulf1.1-A_000091 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3ccc(Cl)cc3)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G02 compound treatment 1.02860387E8 5120000.0 0.26 7.7690583E7 -1.3E7 -0.7 -0.3105 -0.4146 3237376 Sulf1.1-A_000092 CC(C)S(=O)(=O)NCC1CCN(Cc2cccc(OCCO)c2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G03 mock treatment 1.05445584E8 7700000.0 0.39 8.891788E7 -1800000.0 -0.1 0.2107 0.5183 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G04 mock treatment 8.4982794E7 -1.28E7 -0.65 7.6932089E7 -1.38E7 -0.74 -0.9873 -0.998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G05 compound treatment 1.00297416E8 2560000.0 0.13 9.1410939E7 694000.0 0.04 0.1191 0.874 3237466 Sulf1.1-A_000093 Cc1nc(cn1C)S(=O)(=O)N2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G06 compound treatment 9.7369713E7 -371000.0 -0.02 9.3379541E7 2660000.0 0.14 0.0879 0.6079 3237165 Sulf1.1-A_000094 OCCOc1cccc(CN2CCC[C@H](C2)N3C(=O)c4ccccc4C3=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G07 compound treatment 5.0522718E7 -4.72E7 -2.42 5.0417562E7 -4.03E7 -2.17 -3.2458 -0.9985 3237290 Sulf1.1-A_000095 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc(Cl)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G08 compound treatment 9.8293505E7 552000.0 0.03 9.1686112E7 969000.0 0.05 0.0569 0.9587 3237199 Sulf1.1-A_000096 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G09 compound treatment 8.2774262E7 -1.5E7 -0.77 7.8065637E7 -1.27E7 -0.68 -1.0241 -0.9982 3237213 Sulf1.1-A_000097 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cccc4cccnc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G10 compound treatment 9.7890146E7 149000.0 0.01 9.3203875E7 2490000.0 0.13 0.1001 0.7462 3237354 Sulf1.1-A_000098 Cc1nc(cn1C)S(=O)(=O)N[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G11 compound treatment 9.8923291E7 1180000.0 0.06 9.3225905E7 2510000.0 0.14 0.1384 0.9345 3237348 Sulf1.1-A_000099 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cccc4cccnc34)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G12 compound treatment 8.9659933E7 -8080000.0 -0.41 9.1807007E7 1090000.0 0.06 -0.2513 -0.6009 3237154 Sulf1.1-A_000100 OCCOc1ccc(CN2CCC(CC2)N3C(=O)c4ccccc4C3=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G13 compound treatment 8.2321174E7 -1.54E7 -0.79 8.394497E7 -6770000.0 -0.36 -0.8167 -0.9383 3237231 Sulf1.1-A_000101 COc1ccc(cc1)S(=O)(=O)NCC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G14 compound treatment 9.3226427E7 -4510000.0 -0.23 8.9305186E7 -1410000.0 -0.08 -0.2174 -0.8925 3237160 Sulf1.1-A_000102 OCCOc1cccc(CN2CC[C@H](C2)N3C(=O)c4ccccc4C3=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G15 compound treatment 1.07140209E8 9400000.0 0.48 1.00158487E8 9440000.0 0.51 0.7002 0.9996 3237336 Sulf1.1-A_000103 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc(Cl)cc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G16 compound treatment 7.8312447E7 -1.94E7 -1.0 8.5396545E7 -5320000.0 -0.29 -0.9067 -0.8751 3237258 Sulf1.1-A_000104 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G17 compound treatment 9.3382631E7 -4360000.0 -0.22 9.0897247E7 181000.0 0.01 -0.1511 -0.6757 3237440 Sulf1.1-A_000105 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G18 compound treatment 1.02240994E8 4500000.0 0.23 9.8841187E7 8120000.0 0.44 0.4725 0.9553 3237173 Sulf1.1-A_000106 COc1ccc(cc1)S(=O)(=O)NC[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G19 mock treatment 9.1848254E7 -5890000.0 -0.3 8.6797234E7 -3920000.0 -0.21 -0.3628 -0.9846 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G20 mock treatment 8.9683084E7 -8060000.0 -0.41 8.5890517E7 -4830000.0 -0.26 -0.4758 -0.9751 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G21 compound treatment 1.08996777E8 1.13E7 0.58 1.03870424E8 1.32E7 0.71 0.9088 0.9948 3237368 Sulf1.1-A_000107 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3ccc(cc3)c4ccccc4)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G22 compound treatment 8.7248821E7 -1.05E7 -0.54 8.3406999E7 -7310000.0 -0.39 -0.6586 -0.9882 3237402 Sulf1.1-A_000108 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G23 compound treatment 9.6349034E7 -1390000.0 -0.07 9.9940312E7 9220000.0 0.5 0.3008 0.5994 3237211 Sulf1.1-A_000109 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 G24 compound treatment 7.8990893E7 -1.88E7 -0.96 7.653921E7 -1.42E7 -0.76 -1.2194 -0.9935 3237251 Sulf1.1-A_000110 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3cccc4cccnc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H01 compound treatment 4.5062079E7 -5.27E7 -2.7 3.9602377E7 -5.11E7 -2.75 -3.8555 -1.0 3237316 Sulf1.1-A_000111 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc(Cl)c(Cl)c3)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H02 mock treatment 1.02139059E8 4400000.0 0.23 9.2007139E7 1290000.0 0.07 0.2085 0.8841 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H03 mock treatment 1.03215521E8 5470000.0 0.28 9.224611E7 1530000.0 0.08 0.2566 0.8776 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H04 mock treatment 1.01761187E8 4020000.0 0.21 9.579187E7 5080000.0 0.27 0.339 0.9903 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H05 compound treatment 1.04982765E8 7240000.0 0.37 9.5719119E7 5000000.0 0.27 0.4529 0.9876 3237215 Sulf1.1-A_000112 Cc1ccccc1S(=O)(=O)N[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H06 mock treatment 9.5990154E7 -1750000.0 -0.09 9.0000993E7 -716000.0 -0.04 -0.0907 -0.9288 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H07 compound treatment 9.4053376E7 -3690000.0 -0.19 8.7403215E7 -3310000.0 -0.18 -0.2598 -0.9996 3237447 Sulf1.1-A_000113 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3cccc4cccnc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H08 mock treatment 9.0803794E7 -6940000.0 -0.36 8.8518909E7 -2200000.0 -0.12 -0.3351 -0.8942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H09 compound treatment 9.418018E7 -3560000.0 -0.18 8.7033117E7 -3680000.0 -0.2 -0.2693 -0.9991 3237209 Sulf1.1-A_000114 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cc(Cl)ccc3Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H10 mock treatment 9.4913138E7 -2830000.0 -0.14 8.8045378E7 -2670000.0 -0.14 -0.2042 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H11 compound treatment 5.2624357E7 -4.51E7 -2.31 5.00398E7 -4.07E7 -2.19 -3.184 -0.9996 3237245 Sulf1.1-A_000115 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3ccc(Cl)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H12 mock treatment 9.3072875E7 -4670000.0 -0.24 9.0706235E7 -10400.0 0.0 -0.1696 -0.7088 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H13 compound treatment 2.6798862E7 -7.09E7 -3.64 2.6104175E7 -6.46E7 -3.48 -5.0314 -0.9998 3237367 Sulf1.1-A_000116 Cc1ccc(F)cc1S(=O)(=O)NCC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H14 mock treatment 1.02588032E8 4850000.0 0.25 9.3400138E7 2680000.0 0.14 0.2778 0.9668 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H15 compound treatment 3.782568E7 -5.99E7 -3.07 4.8499087E7 -4.22E7 -2.27 -3.779 -0.9891 3237250 Sulf1.1-A_000117 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H16 mock treatment 1.0276825E8 5030000.0 0.26 9.1268654E7 552000.0 0.03 0.2032 0.7835 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H17 compound treatment 5.7327197E7 -4.04E7 -2.07 7.0328882E7 -2.04E7 -1.1 -2.241 -0.9559 3237195 Sulf1.1-A_000118 Cc1ccc(cc1)S(=O)(=O)NC[C@@H]2CCCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H18 mock treatment 1.05095861E8 7350000.0 0.38 9.783966E7 7120000.0 0.38 0.5378 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H19 mock treatment 1.04447641E8 6710000.0 0.34 9.6490868E7 5770000.0 0.31 0.4629 0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H20 mock treatment 1.04136491E8 6400000.0 0.33 1.02332478E8 1.16E7 0.63 0.6741 0.9545 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H21 compound treatment 5.7560788E7 -4.02E7 -2.06 6.0507305E7 -3.02E7 -1.63 -2.6065 -0.9932 3237330 Sulf1.1-A_000119 Cc1ccc(cc1)S(=O)(=O)NC[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H22 mock treatment 1.04927321E8 7190000.0 0.37 1.08939688E8 1.82E7 0.98 0.9543 0.9105 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H23 compound treatment 1.21922089E8 2.42E7 1.24 1.15220413E8 2.45E7 1.32 1.8094 0.9995 3237275 Sulf1.1-A_000120 Cc1ccccc1S(=O)(=O)N[C@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 H24 mock treatment 1.19783433E8 2.2E7 1.13 1.18790698E8 2.81E7 1.51 1.8679 0.9897 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I01 compound treatment 7.3239794E7 -2.45E7 -1.26 7.891044E7 -1.18E7 -0.64 -1.3375 -0.9503 3237314 Sulf1.1-A_000121 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3cc(Cl)ccc3Cl)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I02 compound treatment 7.6542477E7 -2.12E7 -1.09 8.0418028E7 -1.03E7 -0.55 -1.1604 -0.9513 3237346 Sulf1.1-A_000122 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I03 compound treatment 2.8344894E7 -6.94E7 -3.56 2.6367345E7 -6.43E7 -3.47 -4.9653 -0.9999 3237404 Sulf1.1-A_000123 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(Cl)ccc3Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I04 compound treatment 7.4903216E7 -2.28E7 -1.17 6.8571593E7 -2.21E7 -1.19 -1.6709 -1.0 3237340 Sulf1.1-A_000124 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I05 mock treatment 9.1216303E7 -6520000.0 -0.33 9.1177832E7 461000.0 0.02 -0.2189 -0.6528 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I06 mock treatment 9.5868015E7 -1870000.0 -0.1 9.0119574E7 -597000.0 -0.03 -0.0906 -0.8951 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I07 compound treatment 9.827972E7 539000.0 0.03 8.9898148E7 -818000.0 -0.04 -0.0116 -0.2239 3237334 Sulf1.1-A_000125 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I08 compound treatment 8.0801956E7 -1.69E7 -0.87 7.5030626E7 -1.57E7 -0.84 -1.2112 -0.9999 3237162 Sulf1.1-A_000126 OCCOc1cccc(CN2CC[C@@H](C2)N3C(=O)c4ccccc4C3=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I09 compound treatment 5.3398353E7 -4.43E7 -2.27 5.9850354E7 -3.09E7 -1.66 -2.7824 -0.9882 3237468 Sulf1.1-A_000127 CC(C)S(=O)(=O)N1CCN(Cc2cccc(OCCO)c2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I10 compound treatment 7.6471824E7 -2.13E7 -1.09 7.8597721E7 -1.21E7 -0.65 -1.2323 -0.9699 3237295 Sulf1.1-A_000128 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I11 compound treatment 6.4535998E7 -3.32E7 -1.7 6.6591425E7 -2.41E7 -1.3 -2.122 -0.9911 3237424 Sulf1.1-A_000129 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I12 compound treatment 9.3376209E7 -4360000.0 -0.22 8.8366245E7 -2350000.0 -0.13 -0.2477 -0.9636 3237287 Sulf1.1-A_000130 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I13 compound treatment 3.061105E7 -6.71E7 -3.44 4.3712606E7 -4.7E7 -2.53 -4.2227 -0.9886 3237269 Sulf1.1-A_000131 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(Cl)ccc3Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I14 compound treatment 1.00163935E8 2420000.0 0.12 9.1478172E7 762000.0 0.04 0.1168 0.8932 3237155 Sulf1.1-A_000132 OCCOc1ccc(CN2CCC(CN3C(=O)c4ccccc4C3=O)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I15 compound treatment 5.0874419E7 -4.69E7 -2.4 7.2878016E7 -1.78E7 -0.96 -2.3778 -0.9191 3237463 Sulf1.1-A_000133 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3cccc4cccnc34)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I16 compound treatment 8.9131029E7 -8610000.0 -0.44 8.8788379E7 -1930000.0 -0.1 -0.3855 -0.8503 3237410 Sulf1.1-A_000134 Cc1ccccc1S(=O)(=O)N[C@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I17 compound treatment 7.2438715E7 -2.53E7 -1.3 7.2004443E7 -1.87E7 -1.01 -1.6295 -0.9922 3237385 Sulf1.1-A_000135 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I18 compound treatment 1.01499637E8 3760000.0 0.19 9.3820142E7 3100000.0 0.17 0.2544 0.9975 3237167 Sulf1.1-A_000136 OCCOc1cccc(CN2CCC[C@@H](CN3C(=O)c4ccccc4C3=O)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I19 compound treatment 1.00671838E8 2930000.0 0.15 9.9459534E7 8740000.0 0.47 0.4391 0.8886 3237450 Sulf1.1-A_000137 Cc1nc(cn1C)S(=O)(=O)N2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I20 compound treatment 1.08478071E8 1.07E7 0.55 1.03873849E8 1.32E7 0.71 0.8901 0.9922 3237221 Sulf1.1-A_000138 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cccc(F)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I21 mock treatment 9.1637032E7 -6100000.0 -0.31 8.873639E7 -1980000.0 -0.11 -0.2966 -0.8974 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I22 mock treatment 9.4611782E7 -3130000.0 -0.16 9.725594E7 6540000.0 0.35 0.1356 0.3504 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I23 compound treatment 8.1229103E7 -1.65E7 -0.85 7.7867336E7 -1.28E7 -0.69 -1.0877 -0.995 3237187 Sulf1.1-A_000139 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc4ccccc4c3)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 I24 compound treatment 1.21640488E8 2.39E7 1.22 1.1506308E8 2.43E7 1.31 1.7932 0.9994 3237393 Sulf1.1-A_000140 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J01 compound treatment 9.37812E7 -3960000.0 -0.2 1.04349465E8 1.36E7 0.73 0.3756 0.4931 3237433 Sulf1.1-A_000141 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc4ccccc4c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J02 mock treatment 1.11443743E8 1.37E7 0.7 1.0176794E8 1.11E7 0.6 0.9174 0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J03 compound treatment 6.8522559E7 -2.92E7 -1.5 6.0240891E7 -3.05E7 -1.64 -2.2194 -0.999 3237382 Sulf1.1-A_000142 Cc1ccc(F)cc1S(=O)(=O)NC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J04 mock treatment 9.6957111E7 -784000.0 -0.04 9.0371544E7 -345000.0 -0.02 -0.0416 -0.9386 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J05 mock treatment 9.6473295E7 -1270000.0 -0.06 9.384655E7 3130000.0 0.17 0.0732 0.4054 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J06 mock treatment 1.00406147E8 2670000.0 0.14 9.3808927E7 3090000.0 0.17 0.2143 0.9952 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J07 compound treatment 5.1113918E7 -4.66E7 -2.39 5.3239468E7 -3.75E7 -2.02 -3.1169 -0.9965 3237388 Sulf1.1-A_000143 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3ccc4ccccc4c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J08 mock treatment 8.7707752E7 -1.0E7 -0.51 8.0878515E7 -9840000.0 -0.53 -0.7382 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J09 compound treatment 6.5563701E7 -3.22E7 -1.65 6.9161504E7 -2.16E7 -1.16 -1.9869 -0.9852 3237381 Sulf1.1-A_000144 COc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J10 mock treatment 8.5413329E7 -1.23E7 -0.63 8.3712449E7 -7000000.0 -0.38 -0.7135 -0.9696 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J11 compound treatment 2.6585761E7 -7.12E7 -3.65 2.5870551E7 -6.48E7 -3.49 -5.048 -0.9998 3237373 Sulf1.1-A_000145 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3ccc4ccccc4c3)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J12 mock treatment 9.0653008E7 -7090000.0 -0.36 8.9787543E7 -929000.0 -0.05 -0.2923 -0.797 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J13 compound treatment 5.7970329E7 -3.98E7 -2.04 6.8545568E7 -2.22E7 -1.19 -2.2856 -0.9675 3237412 Sulf1.1-A_000146 OCCOc1cccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc4ccccc4c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J14 mock treatment 9.6161217E7 -1580000.0 -0.08 8.9770076E7 -947000.0 -0.05 -0.0933 -0.9751 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J15 compound treatment 8.448014E7 -1.33E7 -0.68 7.8350245E7 -1.24E7 -0.67 -0.9515 -0.9999 3237344 Sulf1.1-A_000147 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cc(Cl)ccc3Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J16 mock treatment 9.5724047E7 -2020000.0 -0.1 8.9266297E7 -1450000.0 -0.08 -0.1283 -0.9904 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J17 compound treatment 8.198863E7 -1.58E7 -0.81 8.3848593E7 -6870000.0 -0.37 -0.8324 -0.9374 3237448 Sulf1.1-A_000148 Cc1ccccc1S(=O)(=O)N2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J18 mock treatment 1.01147622E8 3410000.0 0.17 9.4343146E7 3630000.0 0.2 0.2616 0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J19 compound treatment 8.8332428E7 -9410000.0 -0.48 8.3525965E7 -7190000.0 -0.39 -0.6148 -0.9941 3237362 Sulf1.1-A_000149 OCCOc1cccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J20 mock treatment 1.09876602E8 1.21E7 0.62 1.00245576E8 9530000.0 0.51 0.8027 0.9954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J21 mock treatment 1.02008759E8 4270000.0 0.22 9.7792859E7 7080000.0 0.38 0.4241 0.9653 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J22 mock treatment 1.03032634E8 5290000.0 0.27 1.03311267E8 1.26E7 0.68 0.6714 0.9191 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J23 compound treatment 1.25588837E8 2.78E7 1.43 1.16009638E8 2.53E7 1.36 1.9723 0.9997 3237283 Sulf1.1-A_000150 CC(C)S(=O)(=O)N[C@H]1CCN(Cc2ccc(OCCO)cc2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 J24 mock treatment 1.22076817E8 2.43E7 1.25 1.17840677E8 2.71E7 1.46 1.9148 0.9969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K01 compound treatment 1.04857665E8 7120000.0 0.36 9.7904104E7 7190000.0 0.39 0.5316 0.9996 3237445 Sulf1.1-A_000151 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3cc(Cl)ccc3Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K02 compound treatment 1.00887603E8 3150000.0 0.16 9.927946E7 8560000.0 0.46 0.4401 0.9009 3237164 Sulf1.1-A_000152 OCCOc1cccc(CN2CCC(CN3C(=O)c4ccccc4C3=O)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K03 compound treatment 8.5125159E7 -1.26E7 -0.65 7.2998583E7 -1.77E7 -0.95 -1.1319 -0.982 3237239 Sulf1.1-A_000153 Cc1nc(cn1C)S(=O)(=O)NCC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K04 compound treatment 5.3411717E7 -4.43E7 -2.27 4.9420856E7 -4.13E7 -2.22 -3.179 -0.9999 3237465 Sulf1.1-A_000154 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K05 compound treatment 6.7056609E7 -3.07E7 -1.57 6.2981072E7 -2.77E7 -1.49 -2.1682 -0.9997 3237233 Sulf1.1-A_000155 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3ccc(cc3)c4ccccc4)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K06 compound treatment 9.2232547E7 -5510000.0 -0.28 8.3048769E7 -7670000.0 -0.41 -0.4916 -0.9828 3237201 Sulf1.1-A_000156 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc(Cl)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K07 mock treatment 8.6743717E7 -1.1E7 -0.56 8.1133654E7 -9580000.0 -0.52 -0.7635 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K08 mock treatment 7.4353867E7 -2.34E7 -1.2 7.0611392E7 -2.01E7 -1.08 -1.6131 -0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K09 compound treatment 2.7689184E7 -7.01E7 -3.59 3.2942921E7 -5.78E7 -3.11 -4.7387 -0.9975 3237297 Sulf1.1-A_000157 Cc1ccccc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K10 compound treatment 7.8916174E7 -1.88E7 -0.96 7.4237614E7 -1.65E7 -0.89 -1.3097 -0.9991 3237183 Sulf1.1-A_000158 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3cccc4cccnc34)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K11 compound treatment 7.0809577E7 -2.69E7 -1.38 7.0471715E7 -2.02E7 -1.09 -1.7469 -0.9932 3237171 Sulf1.1-A_000159 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc(Cl)cc3)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K12 compound treatment 4.3191446E7 -5.45E7 -2.8 4.2398732E7 -4.83E7 -2.6 -3.8168 -0.9994 3237418 Sulf1.1-A_000160 CC(C)S(=O)(=O)N[C@H]1CCN(Cc2cccc(OCCO)c2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K13 compound treatment 9.0104796E7 -7640000.0 -0.39 8.6704715E7 -4010000.0 -0.22 -0.4295 -0.9608 3237386 Sulf1.1-A_000161 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3cccc4cccnc34)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K14 compound treatment 9.1520318E7 -6220000.0 -0.32 8.601573E7 -4700000.0 -0.25 -0.4044 -0.9935 3237261 Sulf1.1-A_000162 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc(Cl)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K15 mock treatment 8.2907522E7 -1.48E7 -0.76 7.9238038E7 -1.15E7 -0.62 -0.9747 -0.9947 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K16 mock treatment 8.0510852E7 -1.72E7 -0.88 8.5860482E7 -4860000.0 -0.26 -0.8094 -0.8788 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K17 compound treatment 7.2857236E7 -2.49E7 -1.28 7.8636965E7 -1.21E7 -0.65 -1.3618 -0.9512 3237223 Sulf1.1-A_000163 CC(C)S(=O)(=O)N[C@@H]1CCCN(Cc2ccc(OCCO)cc2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K18 compound treatment 8.8813922E7 -8930000.0 -0.46 8.6311022E7 -4410000.0 -0.24 -0.4913 -0.9532 3237441 Sulf1.1-A_000164 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K19 compound treatment 4.3753722E7 -5.4E7 -2.77 5.2800637E7 -3.79E7 -2.04 -3.4003 -0.9888 3237400 Sulf1.1-A_000165 Cc1ccc(F)cc1S(=O)(=O)N[C@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K20 compound treatment 5.8519287E7 -3.92E7 -2.01 6.2464181E7 -2.83E7 -1.52 -2.4972 -0.9906 3237398 Sulf1.1-A_000166 COc1ccc(cc1)S(=O)(=O)N[C@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K21 compound treatment 1.08157914E8 1.04E7 0.53 1.00661376E8 9940000.0 0.54 0.7562 1.0 3237299 Sulf1.1-A_000167 Cc1nc(cn1C)S(=O)(=O)N[C@@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K22 compound treatment 1.02281978E8 4540000.0 0.23 1.0438404E8 1.37E7 0.74 0.685 0.8874 3237277 Sulf1.1-A_000168 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc4ccccc4c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K23 mock treatment 1.04763073E8 7020000.0 0.36 1.02143477E8 1.14E7 0.62 0.6896 0.9674 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 K24 mock treatment 1.10547945E8 1.28E7 0.66 1.07302265E8 1.66E7 0.89 1.0957 0.9885 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L01 compound treatment 1.05928098E8 8190000.0 0.42 1.0008277E8 9370000.0 0.5 0.6534 0.9958 3237324 Sulf1.1-A_000169 Cc1nc(cn1C)S(=O)(=O)NC[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L02 mock treatment 1.04372706E8 6630000.0 0.34 9.8434951E7 7720000.0 0.42 0.5342 0.995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L03 compound treatment 1.08141754E8 1.04E7 0.53 1.0174498E8 1.1E7 0.59 0.7969 0.9985 3237179 Sulf1.1-A_000170 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3cc(Cl)ccc3Cl)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L04 mock treatment 1.02733307E8 4990000.0 0.26 9.5971296E7 5250000.0 0.28 0.381 0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L05 compound treatment 9.1861677E7 -5880000.0 -0.3 8.1617713E7 -9100000.0 -0.49 -0.5595 -0.9727 3237242 Sulf1.1-A_000171 Cc1ccc(cc1)S(=O)(=O)NCC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L06 mock treatment 9.6824484E7 -917000.0 -0.05 9.2384877E7 1670000.0 0.09 0.0303 0.299 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L07 mock treatment 8.918554E7 -8560000.0 -0.44 8.795852E7 -2760000.0 -0.15 -0.4151 -0.8966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L08 mock treatment 8.6818702E7 -1.09E7 -0.56 7.7149084E7 -1.36E7 -0.73 -0.9125 -0.9914 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L09 compound treatment 5.1716034E7 -4.6E7 -2.36 5.1753054E7 -3.9E7 -2.1 -3.1517 -0.9983 3237293 Sulf1.1-A_000172 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L10 mock treatment 8.8132485E7 -9610000.0 -0.49 8.3488567E7 -7230000.0 -0.39 -0.6235 -0.9932 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L11 compound treatment 5.5489106E7 -4.23E7 -2.17 5.2715644E7 -3.8E7 -2.05 -2.9783 -0.9996 3237255 Sulf1.1-A_000173 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3cccc(F)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L12 mock treatment 9.0729415E7 -7010000.0 -0.36 8.3466107E7 -7250000.0 -0.39 -0.5302 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L13 compound treatment 5.2008886E7 -4.57E7 -2.34 5.5740245E7 -3.5E7 -1.88 -2.9892 -0.9941 3237296 Sulf1.1-A_000174 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cccc4cccnc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L14 mock treatment 9.6527066E7 -1210000.0 -0.06 8.6798246E7 -3920000.0 -0.21 -0.1932 -0.8782 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L15 mock treatment 9.479316E7 -2950000.0 -0.15 8.5470733E7 -5250000.0 -0.28 -0.3066 -0.957 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L16 mock treatment 9.5434722E7 -2310000.0 -0.12 8.8298492E7 -2420000.0 -0.13 -0.1757 -0.9988 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L17 compound treatment 9.3085925E7 -4660000.0 -0.24 8.810224E7 -2610000.0 -0.14 -0.2683 -0.9683 3237338 Sulf1.1-A_000175 COc1ccc(cc1)S(=O)(=O)N[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L18 mock treatment 1.02888989E8 5150000.0 0.26 9.484738E7 4130000.0 0.22 0.3439 0.9964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L19 compound treatment 9.1553807E7 -6190000.0 -0.32 9.5202297E7 4490000.0 0.24 -0.0534 -0.134 3237459 Sulf1.1-A_000176 Cc1ccc(F)cc1S(=O)(=O)N2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L20 mock treatment 1.10142477E8 1.24E7 0.64 1.02049733E8 1.13E7 0.61 0.881 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L21 compound treatment 6.5594515E7 -3.21E7 -1.65 6.4203347E7 -2.65E7 -1.43 -2.1746 -0.9975 3237267 Sulf1.1-A_000177 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L22 mock treatment 1.01279199E8 3540000.0 0.18 1.02152358E8 1.14E7 0.62 0.5637 0.878 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L23 mock treatment 1.03548251E8 5810000.0 0.3 1.01551284E8 1.08E7 0.58 0.623 0.9512 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 L24 mock treatment 1.16746913E8 1.9E7 0.97 1.1141728E8 2.07E7 1.11 1.477 0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M01 compound treatment 1.13805147E8 1.61E7 0.82 1.10179679E8 1.95E7 1.05 1.3233 0.9929 3237244 Sulf1.1-A_000178 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M02 compound treatment 9.2499344E7 -5240000.0 -0.27 9.2098784E7 1380000.0 0.07 -0.1373 -0.4926 3237308 Sulf1.1-A_000179 COc1ccc(cc1)S(=O)(=O)NC[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M03 compound treatment 1.12603362E8 1.49E7 0.76 1.00200399E8 9480000.0 0.51 0.8998 0.9811 3237252 Sulf1.1-A_000180 Cc1ccccc1S(=O)(=O)NC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M04 compound treatment 9.5421412E7 -2320000.0 -0.12 9.947433E7 8760000.0 0.47 0.2494 0.5128 3237470 Sulf1.1-A_000181 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M05 compound treatment 9.8763221E7 1020000.0 0.05 9.4006728E7 3290000.0 0.18 0.1623 0.8786 3237431 Sulf1.1-A_000182 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3cccc4cccnc34)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M06 compound treatment 8.7297133E7 -1.04E7 -0.54 8.9030978E7 -1690000.0 -0.09 -0.4427 -0.8154 3237350 Sulf1.1-A_000183 Cc1ccccc1S(=O)(=O)N[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M07 compound treatment 8.6218533E7 -1.15E7 -0.59 8.3519461E7 -7200000.0 -0.39 -0.6916 -0.9791 3237259 Sulf1.1-A_000184 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M08 compound treatment 6.2282619E7 -3.55E7 -1.82 6.2485642E7 -2.82E7 -1.52 -2.36 -0.9961 3237378 Sulf1.1-A_000185 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M09 mock treatment 7.4164818E7 -2.36E7 -1.21 6.9410823E7 -2.13E7 -1.15 -1.6657 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M10 mock treatment 7.9583786E7 -1.82E7 -0.93 7.0408972E7 -2.03E7 -1.09 -1.4313 -0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M11 compound treatment 7.1950985E7 -2.58E7 -1.32 5.6907857E7 -3.38E7 -1.82 -2.222 -0.9876 3237227 Sulf1.1-A_000186 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M12 compound treatment 7.1720366E7 -2.6E7 -1.33 6.5830683E7 -2.49E7 -1.34 -1.8906 -1.0 3237234 Sulf1.1-A_000187 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3cc(Cl)ccc3Cl)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M13 mock treatment 7.7900041E7 -1.98E7 -1.02 7.0055441E7 -2.07E7 -1.11 -1.5058 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M14 mock treatment 7.7273778E7 -2.05E7 -1.05 7.2509804E7 -1.82E7 -0.98 -1.435 -0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M15 compound treatment 8.855151E7 -9190000.0 -0.47 7.5079057E7 -1.56E7 -0.84 -0.9285 -0.9623 3237462 Sulf1.1-A_000188 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M16 compound treatment 5.1481105E7 -4.63E7 -2.37 4.864302E7 -4.21E7 -2.27 -3.2786 -0.9997 3237169 Sulf1.1-A_000189 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccccc3)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M17 compound treatment 9.0961766E7 -6780000.0 -0.35 8.4882026E7 -5830000.0 -0.31 -0.4679 -0.9987 3237377 Sulf1.1-A_000190 Cc1ccc(cc1)S(=O)(=O)NCC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M18 compound treatment 7.7356039E7 -2.04E7 -1.04 6.8307056E7 -2.24E7 -1.21 -1.5921 -0.9974 3237217 Sulf1.1-A_000191 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc4ccccc4c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M19 compound treatment 3.3170067E7 -6.46E7 -3.31 3.4916352E7 -5.58E7 -3.0 -4.4649 -0.9988 3237291 Sulf1.1-A_000192 COc1ccc(cc1)S(=O)(=O)N[C@@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M20 compound treatment 9.8786434E7 1050000.0 0.05 8.7733955E7 -2980000.0 -0.16 -0.0757 -0.447 3237442 Sulf1.1-A_000193 COc1ccc(cc1)S(=O)(=O)N2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M21 compound treatment 1.15574931E8 1.78E7 0.91 1.07928435E8 1.72E7 0.93 1.3017 1.0 3237302 Sulf1.1-A_000194 Cc1ccc(cc1)S(=O)(=O)N[C@@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M22 compound treatment 1.06798421E8 9060000.0 0.46 9.618656E7 5470000.0 0.29 0.5365 0.9759 3237370 Sulf1.1-A_000195 OCCOc1cccc(CN2CCC(CNS(=O)(=O)c3ccc(Cl)c(Cl)c3)CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M23 compound treatment 1.09483827E8 1.17E7 0.6 1.06849087E8 1.61E7 0.87 1.0399 0.9839 3237303 Sulf1.1-A_000196 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(ccc3Cl)C(F)(F)F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 M24 compound treatment 1.12827459E8 1.51E7 0.77 1.10802575E8 2.01E7 1.08 1.3116 0.9865 3237229 Sulf1.1-A_000197 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3ccccc3)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N01 compound treatment 1.14720393E8 1.7E7 0.87 1.10608569E8 1.99E7 1.07 1.3728 0.9947 3237387 Sulf1.1-A_000198 Cc1ccccc1S(=O)(=O)NC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N02 mock treatment 1.16933151E8 1.92E7 0.98 1.07972181E8 1.73E7 0.93 1.3526 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N03 compound treatment 6.6774782E7 -3.1E7 -1.59 7.7505964E7 -1.32E7 -0.71 -1.6253 -0.9345 3237207 Sulf1.1-A_000199 OCCOc1ccc(CN2CCC[C@H](C2)NS(=O)(=O)c3ccc(cc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N04 mock treatment 9.9853591E7 2110000.0 0.11 9.7484896E7 6770000.0 0.36 0.3343 0.8792 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N05 compound treatment 1.00183947E8 2440000.0 0.13 8.9370008E7 -1350000.0 -0.07 0.0373 0.2575 3237249 Sulf1.1-A_000200 OCCOc1ccc(CN2CCC(CC2)NS(=O)(=O)c3cc(Cl)ccc3Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N06 mock treatment 9.2276487E7 -5460000.0 -0.28 9.253996E7 1820000.0 0.1 -0.1286 -0.4333 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N07 compound treatment 3.9570566E7 -5.82E7 -2.98 3.855674E7 -5.22E7 -2.81 -4.0943 -0.9996 3237236 Sulf1.1-A_000201 OCCOc1ccc(CN2CCC(CNS(=O)(=O)c3cccc4cccnc34)CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N08 mock treatment 8.7415878E7 -1.03E7 -0.53 8.3105722E7 -7610000.0 -0.41 -0.664 -0.992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N09 mock treatment 8.2930489E7 -1.48E7 -0.76 7.4490321E7 -1.62E7 -0.87 -1.1546 -0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N10 mock treatment 8.2423478E7 -1.53E7 -0.79 7.2635859E7 -1.81E7 -0.97 -1.2436 -0.9943 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N11 mock treatment 8.7011575E7 -1.07E7 -0.55 7.240927E7 -1.83E7 -0.99 -1.086 -0.962 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N12 mock treatment 9.1495393E7 -6250000.0 -0.32 7.7073292E7 -1.36E7 -0.73 -0.7459 -0.9307 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N13 mock treatment 9.3937076E7 -3800000.0 -0.19 7.6705863E7 -1.4E7 -0.75 -0.6714 -0.8615 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N14 mock treatment 9.5759635E7 -1980000.0 -0.1 8.0277989E7 -1.04E7 -0.56 -0.4693 -0.8216 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N15 mock treatment 9.7218057E7 -523000.0 -0.03 8.2957692E7 -7760000.0 -0.42 -0.3144 -0.7509 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N16 mock treatment 9.4492243E7 -3250000.0 -0.17 7.9454294E7 -1.13E7 -0.61 -0.5466 -0.8691 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N17 mock treatment 9.7885815E7 145000.0 0.01 8.8592136E7 -2120000.0 -0.11 -0.0757 -0.6599 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N18 mock treatment 1.02644343E8 4900000.0 0.25 8.1314555E7 -9400000.0 -0.51 -0.1803 -0.319 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N19 mock treatment 9.7780146E7 39100.0 0.0 8.7762081E7 -2950000.0 -0.16 -0.1111 -0.6981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N20 mock treatment 1.09330292E8 1.16E7 0.59 1.01609907E8 1.09E7 0.59 0.8348 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N21 mock treatment 9.9286407E7 1550000.0 0.08 8.5981211E7 -4740000.0 -0.26 -0.1243 -0.4655 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N22 mock treatment 1.04604565E8 6860000.0 0.35 9.5430485E7 4710000.0 0.25 0.4282 0.9872 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N23 mock treatment 1.04247619E8 6510000.0 0.33 9.3010656E7 2290000.0 0.12 0.3232 0.9087 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 N24 mock treatment 1.18120296E8 2.04E7 1.04 1.0888833E8 1.82E7 0.98 1.4305 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O01 compound treatment 1.07802971E8 1.01E7 0.52 1.12955988E8 2.22E7 1.2 1.2115 0.9291 3237273 Sulf1.1-A_000202 OCCOc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cccc4cccnc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O02 compound treatment 1.06558863E8 8820000.0 0.45 1.05256713E8 1.45E7 0.78 0.8732 0.9659 3237426 Sulf1.1-A_000203 COc1ccc(cc1)S(=O)(=O)N[C@@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O03 compound treatment 6.1927411E7 -3.58E7 -1.84 6.2750653E7 -2.8E7 -1.51 -2.3628 -0.9952 3237429 Sulf1.1-A_000204 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(Cl)ccc3Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O04 compound treatment 1.03426295E8 5690000.0 0.29 9.9500255E7 8780000.0 0.47 0.5405 0.9729 3237432 Sulf1.1-A_000205 Cc1ccccc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O05 compound treatment 2.6881182E7 -7.09E7 -3.63 2.6756565E7 -6.4E7 -3.44 -5.0035 -0.9996 3237425 Sulf1.1-A_000206 OCCOc1cccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccc(Cl)cc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O06 compound treatment 7.5833698E7 -2.19E7 -1.12 7.7614924E7 -1.31E7 -0.71 -1.2928 -0.9749 3237304 Sulf1.1-A_000207 OCCOc1cccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccccc3)C2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O07 compound treatment 8.9965337E7 -7780000.0 -0.4 8.5835028E7 -4880000.0 -0.26 -0.4677 -0.9796 3237232 Sulf1.1-A_000208 Cc1ccc(F)cc1S(=O)(=O)NCC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O08 compound treatment 8.632482E7 -1.14E7 -0.59 7.3679497E7 -1.7E7 -0.92 -1.0625 -0.9764 3237328 Sulf1.1-A_000209 CC(C)S(=O)(=O)NC[C@@H]1CCCN(Cc2cccc(OCCO)c2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O09 compound treatment 5.9270799E7 -3.85E7 -1.97 5.9189027E7 -3.15E7 -1.7 -2.5947 -0.9972 3237366 Sulf1.1-A_000210 COc1ccc(cc1)S(=O)(=O)NCC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O10 compound treatment 7.289378E7 -2.48E7 -1.27 6.9448903E7 -2.13E7 -1.15 -1.7103 -0.9986 3237292 Sulf1.1-A_000211 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O11 mock treatment 7.5158266E7 -2.26E7 -1.16 7.5347157E7 -1.54E7 -0.83 -1.4037 -0.9865 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O12 mock treatment 7.9950865E7 -1.78E7 -0.91 7.1714803E7 -1.9E7 -1.02 -1.3683 -0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O13 compound treatment 7.0814949E7 -2.69E7 -1.38 7.3694326E7 -1.7E7 -0.92 -1.624 -0.9802 3237389 Sulf1.1-A_000212 Cc1nc(cn1C)S(=O)(=O)NC2CCN(Cc3cccc(OCCO)c3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O14 compound treatment 8.548752E7 -1.23E7 -0.63 7.4240846E7 -1.65E7 -0.89 -1.0715 -0.9857 3237457 Sulf1.1-A_000213 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O15 compound treatment 7.1615336E7 -2.61E7 -1.34 6.9372675E7 -2.13E7 -1.15 -1.7596 -0.9971 3237181 Sulf1.1-A_000214 OCCOc1ccc(CN2CCC[C@@H](CNS(=O)(=O)c3ccc(Cl)c(Cl)c3)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O16 compound treatment 2.7224613E7 -7.05E7 -3.61 2.6568207E7 -6.41E7 -3.45 -4.9983 -0.9997 3237310 Sulf1.1-A_000215 Cc1ccc(F)cc1S(=O)(=O)NC[C@@H]2CCCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O17 compound treatment 7.0997714E7 -2.67E7 -1.37 5.7545497E7 -3.32E7 -1.79 -2.2323 -0.9914 3237451 Sulf1.1-A_000216 OCCOc1ccc(CN2CCN(CC2)S(=O)(=O)c3cccc(F)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O18 compound treatment 9.8190932E7 450000.0 0.02 9.143848E7 722000.0 0.04 0.0438 0.9689 3237434 Sulf1.1-A_000217 Cc1nc(cn1C)S(=O)(=O)N[C@@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O19 compound treatment 6.1832209E7 -3.59E7 -1.84 6.0828522E7 -2.99E7 -1.61 -2.4395 -0.9978 3237263 Sulf1.1-A_000218 COc1ccc(cc1)S(=O)(=O)N[C@H]2CCN(Cc3ccc(OCCO)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O20 compound treatment 7.9789393E7 -1.8E7 -0.92 7.2339835E7 -1.84E7 -0.99 -1.3503 -0.9993 3237300 Sulf1.1-A_000219 OCCOc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cccc(F)c3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O21 compound treatment 7.9348156E7 -1.84E7 -0.94 8.2640342E7 -8080000.0 -0.43 -0.9741 -0.9383 3237461 Sulf1.1-A_000220 OCCOc1cccc(CN2CCN(CC2)S(=O)(=O)c3cc(Cl)ccc3Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O22 compound treatment 8.1448432E7 -1.63E7 -0.84 8.2716801E7 -8000000.0 -0.43 -0.8951 -0.9526 3237237 Sulf1.1-A_000221 Cc1ccccc1S(=O)(=O)NCC2CCN(Cc3ccc(OCCO)cc3)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O23 compound treatment 7.6186535E7 -2.16E7 -1.1 7.067149E7 -2.0E7 -1.08 -1.5444 -0.9999 3237384 Sulf1.1-A_000222 OCCOc1cccc(CN2CCC(CC2)NS(=O)(=O)c3cc(Cl)ccc3Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 O24 compound treatment 8.9617257E7 -8120000.0 -0.42 8.0785771E7 -9930000.0 -0.53 -0.6726 -0.9923 3237414 Sulf1.1-A_000223 Cc1nc(cn1C)S(=O)(=O)N[C@H]2CCN(Cc3cccc(OCCO)c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P01 mock treatment 1.19468426E8 2.17E7 1.11 1.14077657E8 2.34E7 1.26 1.677 0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P02 mock treatment 1.09370735E8 1.16E7 0.6 1.04958282E8 1.42E7 0.77 0.9638 0.9922 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P03 mock treatment 1.04942971E8 7200000.0 0.37 1.00633019E8 9920000.0 0.53 0.6386 0.9837 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P04 mock treatment 1.02271438E8 4530000.0 0.23 9.1939067E7 1220000.0 0.07 0.2107 0.8732 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P05 mock treatment 9.8911337E7 1170000.0 0.06 9.1323662E7 607000.0 0.03 0.0655 0.9593 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P06 mock treatment 9.2193819E7 -5550000.0 -0.28 8.4678178E7 -6040000.0 -0.33 -0.431 -0.9978 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P07 mock treatment 8.9432216E7 -8310000.0 -0.43 8.9022575E7 -1690000.0 -0.09 -0.3656 -0.8395 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P08 mock treatment 9.6017584E7 -1720000.0 -0.09 7.6638829E7 -1.41E7 -0.76 -0.5985 -0.7842 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P09 mock treatment 8.436967E7 -1.34E7 -0.69 9.1050475E7 334000.0 0.02 -0.4719 -0.6883 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P10 mock treatment 8.0689137E7 -1.71E7 -0.87 7.2060714E7 -1.87E7 -1.0 -1.3284 -0.9976 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P11 mock treatment 8.1260151E7 -1.65E7 -0.84 7.8275033E7 -1.24E7 -0.67 -1.071 -0.9934 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P12 mock treatment 8.293747E7 -1.48E7 -0.76 7.4666443E7 -1.61E7 -0.86 -1.1477 -0.9979 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P13 mock treatment 8.5208881E7 -1.25E7 -0.64 8.0411463E7 -1.03E7 -0.55 -0.8466 -0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P14 mock treatment 8.6332008E7 -1.14E7 -0.58 8.0440282E7 -1.03E7 -0.55 -0.8048 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P15 mock treatment 8.7291535E7 -1.04E7 -0.54 8.2020623E7 -8700000.0 -0.47 -0.7098 -0.9978 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P16 mock treatment 8.8511289E7 -9230000.0 -0.47 8.3055575E7 -7660000.0 -0.41 -0.6262 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P17 mock treatment 9.1913787E7 -5830000.0 -0.3 8.3679182E7 -7040000.0 -0.38 -0.4792 -0.993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P18 mock treatment 9.2846444E7 -4890000.0 -0.25 8.6696962E7 -4020000.0 -0.22 -0.3304 -0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P19 mock treatment 9.5514512E7 -2230000.0 -0.11 8.8967708E7 -1750000.0 -0.09 -0.1473 -0.9955 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P20 mock treatment 9.6913478E7 -828000.0 -0.04 9.1770046E7 1050000.0 0.06 0.0101 0.1429 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P21 mock treatment 9.9164167E7 1420000.0 0.07 9.2858111E7 2140000.0 0.12 0.1331 0.9756 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P22 mock treatment 1.02547396E8 4810000.0 0.25 9.5519842E7 4800000.0 0.26 0.3571 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P23 mock treatment 1.12578584E8 1.48E7 0.76 1.02641461E8 1.19E7 0.64 0.9918 0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2168 P24 mock treatment 1.24770095E8 2.7E7 1.39 1.12861029E8 2.21E7 1.19 1.8228 0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A01 compound treatment 8.2908223E7 -9690000.0 -0.5 7.8453438E7 -1.27E7 -0.69 -0.8358 -0.9875 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A02 compound treatment 1.06525952E8 1.39E7 0.71 9.9882135E7 8700000.0 0.47 0.8361 0.9792 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A03 compound treatment 1.10388789E8 1.78E7 0.91 1.07463886E8 1.63E7 0.88 1.2648 0.9998 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A04 compound treatment 9.9596696E7 7000000.0 0.36 9.6612484E7 5430000.0 0.29 0.4605 0.9949 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A05 compound treatment 1.12092844E8 1.95E7 1.0 1.02742711E8 1.16E7 0.62 1.1468 0.9741 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A06 compound treatment 9.684786E7 4250000.0 0.22 8.0699918E7 -1.05E7 -0.56 -0.245 -0.4051 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A07 compound treatment 1.08268791E8 1.57E7 0.8 1.00123694E8 8950000.0 0.48 0.9085 0.9701 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A08 compound treatment 1.1371181E8 2.11E7 1.08 1.03413648E8 1.22E7 0.66 1.231 0.9717 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A09 compound treatment 4.1948802E7 -5.07E7 -2.6 4.1144486E7 -5.0E7 -2.69 -3.7408 -0.9998 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A10 compound treatment 1.01005506E8 8410000.0 0.43 8.593708E7 -5240000.0 -0.28 0.1051 0.204 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A11 compound treatment 9.0808693E7 -1790000.0 -0.09 8.1774344E7 -9400000.0 -0.51 -0.423 -0.8219 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A12 compound treatment 1.05644989E8 1.3E7 0.67 9.597446E7 4800000.0 0.26 0.6554 0.9144 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A13 mock treatment 1.1191862E8 1.93E7 0.99 1.0910771E8 1.79E7 0.97 1.3829 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A14 mock treatment 1.08639729E8 1.6E7 0.82 9.9256116E7 8080000.0 0.44 0.8889 0.9557 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A15 compound treatment 8.5788091E7 -6810000.0 -0.35 7.4043841E7 -1.71E7 -0.92 -0.8993 -0.9116 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A16 compound treatment 1.09146408E8 1.65E7 0.85 1.03081325E8 1.19E7 0.64 1.0529 0.9905 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A17 compound treatment 9.3939016E7 1340000.0 0.07 8.6343433E7 -4830000.0 -0.26 -0.1356 -0.5035 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A18 compound treatment 1.2080855E8 2.82E7 1.45 1.15749127E8 2.46E7 1.32 1.9579 0.999 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A19 compound treatment 1.12483122E8 1.99E7 1.02 1.00813963E8 9640000.0 0.52 1.0875 0.951 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A20 compound treatment 1.137089E8 2.11E7 1.08 1.04981425E8 1.38E7 0.74 1.2906 0.9832 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A21 compound treatment 7.9573448E7 -1.3E7 -0.67 7.528185E7 -1.59E7 -0.86 -1.0774 -0.9924 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A22 compound treatment 1.18276741E8 2.57E7 1.32 1.18619974E8 2.74E7 1.48 1.9755 0.9983 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A23 compound treatment 1.10502207E8 1.79E7 0.92 1.01863547E8 1.07E7 0.58 1.0557 0.9747 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 A24 compound treatment 1.28828365E8 3.62E7 1.86 1.22281115E8 3.11E7 1.67 2.4973 0.9987 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B01 compound treatment 1.23529662E8 3.09E7 1.59 1.21064469E8 2.99E7 1.61 2.259 1.0 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B02 compound treatment 9.7600813E7 5000000.0 0.26 9.6556572E7 5380000.0 0.29 0.3861 0.9981 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B03 compound treatment 7.5044702E7 -1.76E7 -0.9 6.1276635E7 -2.99E7 -1.61 -1.7748 -0.9622 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B04 compound treatment 5.2339075E7 -4.03E7 -2.06 4.5224066E7 -4.6E7 -2.47 -3.2089 -0.9959 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B05 compound treatment 9.7451547E7 4850000.0 0.25 9.921353E7 8040000.0 0.43 0.4818 0.9654 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B06 compound treatment 9.0011623E7 -2590000.0 -0.13 8.1271329E7 -9910000.0 -0.53 -0.471 -0.8568 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B07 compound treatment 5.9389504E7 -3.32E7 -1.7 6.5174459E7 -2.6E7 -1.4 -2.1937 -0.9953 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B08 compound treatment 5.7990658E7 -3.46E7 -1.77 5.3477625E7 -3.77E7 -2.03 -2.6898 -0.9977 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B09 compound treatment 9.7759461E7 5160000.0 0.26 9.4052415E7 2870000.0 0.15 0.2964 0.9675 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B10 compound treatment 9.3285254E7 685000.0 0.04 9.2978243E7 1800000.0 0.1 0.0934 0.9057 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B11 compound treatment 8.4953656E7 -7650000.0 -0.39 7.4449701E7 -1.67E7 -0.9 -0.9141 -0.9305 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B12 compound treatment 4.0611136E7 -5.2E7 -2.66 3.2756632E7 -5.84E7 -3.15 -4.1087 -0.9966 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B13 mock treatment 9.6253336E7 3650000.0 0.19 9.6311196E7 5130000.0 0.28 0.3279 0.982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B14 mock treatment 9.7135924E7 4540000.0 0.23 8.9234701E7 -1940000.0 -0.1 0.0904 0.3546 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B15 compound treatment 6.269353E7 -2.99E7 -1.53 4.5970295E7 -4.52E7 -2.43 -2.8053 -0.9751 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B16 compound treatment 2.613911E7 -6.65E7 -3.41 2.5266921E7 -6.59E7 -3.55 -4.9184 -0.9998 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B17 compound treatment 9.2128799E7 -471000.0 -0.02 8.3315015E7 -7860000.0 -0.42 -0.3165 -0.7462 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B18 compound treatment 1.00373983E8 7770000.0 0.4 9.1433287E7 255000.0 0.01 0.2915 0.7311 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B19 compound treatment 1.03334781E8 1.07E7 0.55 9.3404373E7 2230000.0 0.12 0.4738 0.8415 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B20 compound treatment 1.09530455E8 1.69E7 0.87 1.01793467E8 1.06E7 0.57 1.0178 0.9795 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B21 compound treatment 1.04153032E8 1.16E7 0.59 9.749303E7 6320000.0 0.34 0.6592 0.9653 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B22 compound treatment 2.5726012E7 -6.69E7 -3.43 2.5212741E7 -6.6E7 -3.55 -4.9354 -0.9998 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B23 compound treatment 8.3336251E7 -9260000.0 -0.47 7.8787733E7 -1.24E7 -0.67 -0.8075 -0.9861 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 B24 compound treatment 4.3974129E7 -4.86E7 -2.49 4.1353868E7 -4.98E7 -2.68 -3.6595 -0.9993 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C01 compound treatment 1.0366214E8 1.11E7 0.57 1.02719577E8 1.15E7 0.62 0.8404 0.9989 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C02 compound treatment 9.817345E7 5570000.0 0.29 9.5402385E7 4220000.0 0.23 0.3629 0.9936 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C03 compound treatment 9.3213906E7 614000.0 0.03 9.0965895E7 -212000.0 -0.01 0.0142 0.4237 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C04 compound treatment 9.5060848E7 2460000.0 0.13 9.4164882E7 2990000.0 0.16 0.2029 0.9928 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C05 compound treatment 2.939447E7 -6.32E7 -3.24 2.6803541E7 -6.44E7 -3.47 -4.7419 -0.9994 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C06 compound treatment 8.9422782E7 -3180000.0 -0.16 9.7074672E7 5900000.0 0.32 0.1094 0.3066 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C07 compound treatment 8.9098615E7 -3500000.0 -0.18 8.9517388E7 -1660000.0 -0.09 -0.1901 -0.9483 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C08 compound treatment 8.6170809E7 -6430000.0 -0.33 8.5354989E7 -5820000.0 -0.31 -0.4547 -0.9997 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C09 compound treatment 1.01114953E8 8520000.0 0.44 9.9404448E7 8230000.0 0.44 0.6219 1.0 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C10 compound treatment 8.3243943E7 -9360000.0 -0.48 8.149883E7 -9680000.0 -0.52 -0.7076 -0.9991 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C11 mock treatment 9.5277976E7 2680000.0 0.14 9.4822967E7 3650000.0 0.2 0.2359 0.9847 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C12 mock treatment 8.7159131E7 -5440000.0 -0.28 8.5488202E7 -5690000.0 -0.31 -0.4138 -0.9989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C13 compound treatment 8.5920278E7 -6680000.0 -0.34 8.5780467E7 -5400000.0 -0.29 -0.4476 -0.9967 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C14 compound treatment 9.0667233E7 -1930000.0 -0.1 8.5464573E7 -5710000.0 -0.31 -0.2876 -0.8898 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C15 mock treatment 9.3149962E7 550000.0 0.03 8.4971366E7 -6210000.0 -0.33 -0.2164 -0.6452 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C16 mock treatment 9.3384934E7 785000.0 0.04 8.4503654E7 -6670000.0 -0.36 -0.2257 -0.624 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C17 compound treatment 9.8117398E7 5520000.0 0.28 8.6301421E7 -4880000.0 -0.26 0.0143 0.037 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C18 compound treatment 9.2358014E7 -242000.0 -0.01 8.4117531E7 -7060000.0 -0.38 -0.2776 -0.7298 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C19 compound treatment 9.1175052E7 -1420000.0 -0.07 8.3819795E7 -7360000.0 -0.4 -0.3318 -0.8236 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C20 compound treatment 9.317444E7 575000.0 0.03 8.2464517E7 -8710000.0 -0.47 -0.311 -0.6614 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C21 compound treatment 1.19053732E8 2.65E7 1.36 1.10601634E8 1.94E7 1.05 1.6983 0.9918 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C22 compound treatment 9.5666485E7 3070000.0 0.16 9.6559618E7 5380000.0 0.29 0.3161 0.9587 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C23 compound treatment 1.22554522E8 3.0E7 1.54 1.2156654E8 3.04E7 1.64 2.2427 0.9995 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 C24 compound treatment 1.18925893E8 2.63E7 1.35 1.12349828E8 2.12E7 1.14 1.7603 0.9965 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D01 compound treatment 1.07255835E8 1.47E7 0.75 1.04058251E8 1.29E7 0.69 1.0216 0.9992 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D02 compound treatment 9.2718211E7 118000.0 0.01 9.1365727E7 188000.0 0.01 0.0114 0.9701 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D03 compound treatment 7.9516442E7 -1.31E7 -0.67 7.7301998E7 -1.39E7 -0.75 -1.0025 -0.9985 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D04 compound treatment 8.4024482E7 -8580000.0 -0.44 8.0911055E7 -1.03E7 -0.55 -0.7017 -0.9935 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D05 compound treatment 2.6218089E7 -6.64E7 -3.4 2.5528319E7 -6.56E7 -3.54 -4.9056 -0.9998 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D06 compound treatment 9.0434502E7 -2170000.0 -0.11 9.2250633E7 1070000.0 0.06 -0.0376 -0.3007 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D07 compound treatment 6.8433917E7 -2.42E7 -1.24 6.7141463E7 -2.4E7 -1.29 -1.7911 -0.9998 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D08 compound treatment 8.9868032E7 -2730000.0 -0.14 9.14759E7 298000.0 0.02 -0.0877 -0.622 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D09 compound treatment 8.3404032E7 -9200000.0 -0.47 8.1997406E7 -9180000.0 -0.49 -0.6828 -0.9997 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D10 compound treatment 7.2925825E7 -1.97E7 -1.01 7.5883446E7 -1.53E7 -0.82 -1.2954 -0.995 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D11 mock treatment 9.6920762E7 4320000.0 0.22 9.637051E7 5190000.0 0.28 0.3543 0.9933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D12 mock treatment 9.524841E7 2650000.0 0.14 9.4268192E7 3090000.0 0.17 0.2137 0.9949 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D13 compound treatment 9.4259756E7 1660000.0 0.09 9.5553905E7 4380000.0 0.24 0.2268 0.9052 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D14 compound treatment 6.876217E7 -2.38E7 -1.22 6.9829003E7 -2.13E7 -1.15 -1.6768 -0.9995 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D15 mock treatment 9.951286E7 6910000.0 0.35 9.3462045E7 2280000.0 0.12 0.3375 0.8999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D16 mock treatment 1.01532426E8 8930000.0 0.46 9.6600295E7 5420000.0 0.29 0.5302 0.9764 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D17 compound treatment 8.7045949E7 -5550000.0 -0.28 8.8712719E7 -2470000.0 -0.13 -0.2951 -0.9397 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D18 compound treatment 9.3330943E7 731000.0 0.04 9.1191988E7 14100.0 0.0 0.027 0.7213 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D19 compound treatment 8.9599102E7 -3000000.0 -0.15 9.3716618E7 2540000.0 0.14 -0.0121 -0.0587 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D20 compound treatment 7.4442683E7 -1.82E7 -0.93 7.547082E7 -1.57E7 -0.85 -1.2561 -0.9989 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D21 compound treatment 9.1471647E7 -1130000.0 -0.06 9.3486457E7 2310000.0 0.12 0.047 0.343 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D22 compound treatment 1.02684674E8 1.01E7 0.52 1.01766613E8 1.06E7 0.57 0.7687 0.9988 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D23 compound treatment 1.004723E8 7870000.0 0.4 9.6738325E7 5560000.0 0.3 0.497 0.9892 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 D24 compound treatment 9.9833715E7 7230000.0 0.37 9.4763566E7 3590000.0 0.19 0.3987 0.9538 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E01 mock treatment 1.07207034E8 1.46E7 0.75 1.00870672E8 9690000.0 0.52 0.8985 0.9845 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E02 mock treatment 9.5715492E7 3120000.0 0.16 1.01375217E8 1.02E7 0.55 0.5012 0.8764 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E03 compound treatment 1.21865148E8 2.93E7 1.5 1.21369928E8 3.02E7 1.63 2.2103 0.9992 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E04 compound treatment 8.9576461E7 -3020000.0 -0.15 8.9217439E7 -1960000.0 -0.11 -0.1842 -0.9825 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E05 compound treatment 1.07620661E8 1.5E7 0.77 1.17493328E8 2.63E7 1.42 1.5464 0.9589 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E06 compound treatment 1.01230307E8 8630000.0 0.44 9.7899303E7 6720000.0 0.36 0.5687 0.995 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E07 compound treatment 9.0088933E7 -2510000.0 -0.13 8.767996E7 -3500000.0 -0.19 -0.2242 -0.9827 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E08 compound treatment 9.917016E7 6570000.0 0.34 9.1080012E7 -97800.0 -0.01 0.2344 0.696 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E09 mock treatment 8.939762E7 -3200000.0 -0.16 8.8536652E7 -2640000.0 -0.14 -0.2166 -0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E10 mock treatment 9.1527512E7 -1070000.0 -0.05 8.8155239E7 -3020000.0 -0.16 -0.154 -0.8962 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E11 compound treatment 6.3697857E7 -2.89E7 -1.48 5.7998864E7 -3.32E7 -1.79 -2.3108 -0.9957 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E12 compound treatment 9.5060586E7 2460000.0 0.13 9.5258342E7 4080000.0 0.22 0.2446 0.9653 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E13 compound treatment 8.7079543E7 -5520000.0 -0.28 8.4620086E7 -6560000.0 -0.35 -0.4498 -0.994 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E14 compound treatment 9.0557744E7 -2040000.0 -0.1 8.9560472E7 -1620000.0 -0.09 -0.1356 -0.9958 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E15 compound treatment 9.2976771E7 377000.0 0.02 9.2199782E7 1020000.0 0.06 0.0526 0.9014 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E16 compound treatment 9.3528947E7 929000.0 0.05 9.0558964E7 -619000.0 -0.03 0.0101 0.1739 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E17 mock treatment 9.8839387E7 6240000.0 0.32 9.569808E7 4520000.0 0.24 0.3983 0.9909 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E18 mock treatment 9.8471334E7 5870000.0 0.3 9.5742629E7 4560000.0 0.25 0.3866 0.995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E19 compound treatment 9.9496583E7 6900000.0 0.35 9.9395823E7 8220000.0 0.44 0.5629 0.9938 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E20 compound treatment 1.02991601E8 1.04E7 0.53 9.864517E7 7470000.0 0.4 0.661 0.9904 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E21 compound treatment 9.7780187E7 5180000.0 0.27 9.907696E7 7900000.0 0.43 0.4885 0.9743 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E22 compound treatment 1.08866808E8 1.63E7 0.83 1.05775114E8 1.46E7 0.79 1.1454 0.9996 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E23 compound treatment 1.01889277E8 9290000.0 0.48 9.8448411E7 7270000.0 0.39 0.6135 0.9953 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 E24 compound treatment 1.14815693E8 2.22E7 1.14 1.08346603E8 1.72E7 0.92 1.4589 0.9947 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F01 mock treatment 1.17501423E8 2.49E7 1.28 1.13006363E8 2.18E7 1.18 1.7337 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F02 mock treatment 1.04655886E8 1.21E7 0.62 1.04647944E8 1.35E7 0.73 0.9498 0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F03 compound treatment 6.4025813E7 -2.86E7 -1.46 6.1123282E7 -3.01E7 -1.62 -2.18 -0.9988 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F04 compound treatment 8.3811451E7 -8790000.0 -0.45 8.2940806E7 -8240000.0 -0.44 -0.6322 -1.0 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F05 compound treatment 9.0396975E7 -2200000.0 -0.11 9.0221879E7 -956000.0 -0.05 -0.1162 -0.9367 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F06 compound treatment 6.8563051E7 -2.4E7 -1.23 6.1653007E7 -2.95E7 -1.59 -1.9954 -0.992 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F07 compound treatment 9.8436437E7 5840000.0 0.3 9.4380807E7 3200000.0 0.17 0.3335 0.9658 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F08 compound treatment 8.5167945E7 -7430000.0 -0.38 8.5081704E7 -6100000.0 -0.33 -0.5015 -0.9973 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F09 mock treatment 9.4630365E7 2030000.0 0.1 9.096033E7 -218000.0 -0.01 0.0653 0.6236 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F10 mock treatment 9.019017E7 -2410000.0 -0.12 8.7506783E7 -3670000.0 -0.2 -0.2271 -0.9743 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F11 compound treatment 8.5195927E7 -7400000.0 -0.38 8.5636169E7 -5540000.0 -0.3 -0.4793 -0.9929 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F12 compound treatment 9.0362889E7 -2240000.0 -0.11 8.8964134E7 -2210000.0 -0.12 -0.1654 -0.9998 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F13 compound treatment 2.887619E7 -6.37E7 -3.27 2.8014516E7 -6.32E7 -3.4 -4.7146 -0.9998 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F14 compound treatment 9.4492724E7 1890000.0 0.1 9.0545629E7 -632000.0 -0.03 0.0445 0.4331 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F15 compound treatment 9.0254712E7 -2350000.0 -0.12 9.171705E7 539000.0 0.03 -0.0645 -0.5213 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F16 compound treatment 8.7845175E7 -4750000.0 -0.24 8.6991239E7 -4190000.0 -0.23 -0.3317 -0.9992 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F17 mock treatment 9.9547514E7 6950000.0 0.36 9.7964293E7 6790000.0 0.37 0.5102 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F18 mock treatment 9.7128326E7 4530000.0 0.23 9.4739915E7 3560000.0 0.19 0.2998 0.9955 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F19 compound treatment 8.6214252E7 -6390000.0 -0.33 8.2365658E7 -8810000.0 -0.47 -0.567 -0.9835 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F20 compound treatment 4.7107729E7 -4.55E7 -2.33 4.514043E7 -4.6E7 -2.48 -3.4017 -0.9995 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F21 compound treatment 1.01746366E8 9150000.0 0.47 1.01566104E8 1.04E7 0.56 0.727 0.9961 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F22 compound treatment 1.08183926E8 1.56E7 0.8 1.0225755E8 1.11E7 0.6 0.9867 0.9897 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F23 compound treatment 8.0737168E7 -1.19E7 -0.61 7.8414393E7 -1.28E7 -0.69 -0.9159 -0.9981 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 F24 compound treatment 1.1883775E8 2.62E7 1.34 1.16332847E8 2.52E7 1.35 1.9088 1.0 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G01 compound treatment 1.11528863E8 1.89E7 0.97 1.09523624E8 1.83E7 0.99 1.3846 1.0 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G02 compound treatment 1.01249932E8 8650000.0 0.44 1.02409625E8 1.12E7 0.6 0.7412 0.9883 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G03 mock treatment 1.01921827E8 9320000.0 0.48 9.8997063E7 7820000.0 0.42 0.6356 0.998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G04 mock treatment 9.456737E7 1970000.0 0.1 9.1850345E7 673000.0 0.04 0.0969 0.9045 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G05 compound treatment 7.886313E7 -1.37E7 -0.7 7.7779633E7 -1.34E7 -0.72 -1.008 -0.9999 PK04_181123 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G06 compound treatment 1.00905693E8 8310000.0 0.43 9.8453732E7 7280000.0 0.39 0.5781 0.9991 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G07 compound treatment 8.9058335E7 -3540000.0 -0.18 8.8973083E7 -2200000.0 -0.12 -0.2123 -0.9788 PK04_181125 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G08 compound treatment 9.2204739E7 -395000.0 -0.02 9.1379137E7 201000.0 0.01 -0.0067 -0.2897 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G09 compound treatment 8.9658304E7 -2940000.0 -0.15 8.6720082E7 -4460000.0 -0.24 -0.2763 -0.9749 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G10 compound treatment 9.5772817E7 3170000.0 0.16 9.1195286E7 17400.0 0.0 0.1157 0.7112 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G11 compound treatment 9.5227107E7 2630000.0 0.13 9.4707496E7 3530000.0 0.19 0.2296 0.9857 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G12 compound treatment 8.2455539E7 -1.01E7 -0.52 8.5811096E7 -5370000.0 -0.29 -0.572 -0.9616 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G13 compound treatment 7.7609994E7 -1.5E7 -0.77 7.7502451E7 -1.37E7 -0.74 -1.064 -0.9998 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G14 compound treatment 8.0446995E7 -1.22E7 -0.62 8.080348E7 -1.04E7 -0.56 -0.8355 -0.9985 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G15 compound treatment 8.5045406E7 -7550000.0 -0.39 8.9889635E7 -1290000.0 -0.07 -0.3228 -0.8207 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G16 compound treatment 9.1335975E7 -1260000.0 -0.06 9.1413604E7 236000.0 0.01 -0.0368 -0.5579 3561954 PK04_181134 COc1ccccc1/C=C/CO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G17 compound treatment 8.7812302E7 -4790000.0 -0.25 8.5979618E7 -5200000.0 -0.28 -0.3714 -0.9978 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G18 compound treatment 7.9034722E7 -1.36E7 -0.7 8.4349042E7 -6830000.0 -0.37 -0.7516 -0.9557 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G19 mock treatment 9.6906473E7 4310000.0 0.22 9.561962E7 4440000.0 0.24 0.3252 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G20 mock treatment 9.5439019E7 2840000.0 0.15 9.6497459E7 5320000.0 0.29 0.3055 0.9507 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G21 compound treatment 1.08531833E8 1.59E7 0.82 1.04908631E8 1.37E7 0.74 1.1002 0.9988 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G22 compound treatment 1.04384222E8 1.18E7 0.6 9.6902951E7 5730000.0 0.31 0.6451 0.9513 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G23 compound treatment 1.0464254E8 1.2E7 0.62 9.9620061E7 8440000.0 0.45 0.7579 0.9887 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 G24 compound treatment 1.17076768E8 2.45E7 1.25 1.08981928E8 1.78E7 0.96 1.565 0.9912 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H01 compound treatment 1.01769005E8 9170000.0 0.47 1.02592898E8 1.14E7 0.61 0.767 0.9912 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H02 compound treatment 9.5707951E7 3110000.0 0.16 8.8224264E7 -2950000.0 -0.16 2.0E-4 8.0E-4 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H03 mock treatment 1.00876735E8 8280000.0 0.42 1.00853279E8 9680000.0 0.52 0.6684 0.9948 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H04 mock treatment 9.6889815E7 4290000.0 0.22 9.4182423E7 3000000.0 0.16 0.2699 0.9886 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H05 compound treatment 7.1699067E7 -2.09E7 -1.07 7.1912149E7 -1.93E7 -1.04 -1.4911 -0.9999 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H06 compound treatment 6.4443032E7 -2.82E7 -1.44 6.3639778E7 -2.75E7 -1.48 -2.069 -0.9999 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H07 compound treatment 9.5719491E7 3120000.0 0.16 9.9016255E7 7840000.0 0.42 0.4115 0.9117 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H08 compound treatment 8.6256857E7 -6340000.0 -0.33 8.5756724E7 -5420000.0 -0.29 -0.4363 -0.9986 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H09 compound treatment 3.650166E7 -5.61E7 -2.88 5.8316658E7 -3.29E7 -1.77 -3.2844 -0.9728 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H10 compound treatment 7.0177307E7 -2.24E7 -1.15 7.4622851E7 -1.66E7 -0.89 -1.443 -0.9921 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H11 compound treatment 8.0677685E7 -1.19E7 -0.61 7.7803624E7 -1.34E7 -0.72 -0.9413 -0.9967 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H12 compound treatment 8.8265486E7 -4330000.0 -0.22 9.0785274E7 -393000.0 -0.02 -0.172 -0.7709 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H13 compound treatment 6.5304479E7 -2.73E7 -1.4 6.3679089E7 -2.75E7 -1.48 -2.0363 -0.9996 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H14 compound treatment 9.2757617E7 158000.0 0.01 9.1170341E7 -7500.0 0.0 0.0054 0.671 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H15 compound treatment 8.9199221E7 -3400000.0 -0.17 8.8125576E7 -3050000.0 -0.16 -0.2395 -0.9996 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H16 compound treatment 5.6262014E7 -3.63E7 -1.86 5.3311008E7 -3.79E7 -2.04 -2.7588 -0.999 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H17 compound treatment 9.3769361E7 1170000.0 0.06 9.1429674E7 252000.0 0.01 0.052 0.8457 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H18 compound treatment 7.9472421E7 -1.31E7 -0.67 7.7798392E7 -1.34E7 -0.72 -0.9852 -0.9994 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H19 mock treatment 1.05050262E8 1.25E7 0.64 9.7150266E7 5970000.0 0.32 0.6786 0.9497 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H20 mock treatment 9.6524962E7 3930000.0 0.2 9.6984146E7 5810000.0 0.31 0.3633 0.9773 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H21 compound treatment 7.3425657E7 -1.92E7 -0.98 7.7944482E7 -1.32E7 -0.71 -1.1988 -0.9875 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H22 compound treatment 2.6638361E7 -6.6E7 -3.38 2.6213853E7 -6.5E7 -3.5 -4.8642 -0.9999 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H23 compound treatment 2.7568519E7 -6.5E7 -3.33 2.7098937E7 -6.41E7 -3.45 -4.7968 -0.9998 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 H24 compound treatment 9.9929956E7 7330000.0 0.38 9.683835E7 5660000.0 0.3 0.4812 0.9946 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I01 compound treatment 8.8470468E7 -4130000.0 -0.21 8.8938992E7 -2240000.0 -0.12 -0.2349 -0.9644 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I02 compound treatment 9.9592529E7 6990000.0 0.36 9.3282201E7 2100000.0 0.11 0.3336 0.8874 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I03 compound treatment 8.7800218E7 -4800000.0 -0.25 8.7141103E7 -4040000.0 -0.22 -0.3277 -0.9981 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I04 compound treatment 9.7105112E7 4510000.0 0.23 9.3237362E7 2060000.0 0.11 0.2417 0.9435 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I05 mock treatment 8.8626114E7 -3970000.0 -0.2 9.5559799E7 4380000.0 0.24 0.0228 0.0733 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I06 mock treatment 8.6582198E7 -6020000.0 -0.31 9.3649578E7 2470000.0 0.13 -0.124 -0.369 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I07 compound treatment 8.2753646E7 -9850000.0 -0.5 7.9927171E7 -1.13E7 -0.61 -0.7852 -0.9959 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I08 compound treatment 8.4181111E7 -8420000.0 -0.43 8.4004318E7 -7170000.0 -0.39 -0.5783 -0.9985 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I09 compound treatment 5.907723E7 -3.35E7 -1.72 6.1990398E7 -2.92E7 -1.57 -2.3263 -0.999 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I10 compound treatment 5.2048049E7 -4.06E7 -2.08 5.4957634E7 -3.62E7 -1.95 -2.8488 -0.9995 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I11 compound treatment 6.9869779E7 -2.27E7 -1.16 7.7861666E7 -1.33E7 -0.72 -1.3308 -0.9728 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I12 compound treatment 8.2537143E7 -1.01E7 -0.52 8.0085775E7 -1.11E7 -0.6 -0.787 -0.9973 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I13 compound treatment 8.149929E7 -1.11E7 -0.57 7.7681781E7 -1.35E7 -0.73 -0.9162 -0.9927 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I14 compound treatment 8.709014E7 -5510000.0 -0.28 8.7497922E7 -3680000.0 -0.2 -0.3398 -0.985 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I15 compound treatment 8.1795762E7 -1.08E7 -0.55 8.2001029E7 -9180000.0 -0.49 -0.741 -0.9984 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I16 compound treatment 8.7908732E7 -4690000.0 -0.24 8.525856E7 -5920000.0 -0.32 -0.3954 -0.9903 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I17 compound treatment 7.8274545E7 -1.43E7 -0.73 8.2300551E7 -8880000.0 -0.48 -0.8572 -0.9784 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I18 compound treatment 9.2503111E7 -96700.0 0.0 9.1186396E7 8550.0 0.0 -0.0032 -0.6386 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I19 compound treatment 9.6717796E7 4120000.0 0.21 9.6596116E7 5420000.0 0.29 0.3556 0.9874 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I20 compound treatment 9.8604599E7 6000000.0 0.31 9.5531418E7 4350000.0 0.23 0.3834 0.991 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I21 mock treatment 9.7454539E7 4850000.0 0.25 9.7216145E7 6040000.0 0.33 0.4059 0.9913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I22 mock treatment 9.9540078E7 6940000.0 0.36 9.876964E7 7590000.0 0.41 0.5406 0.9976 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I23 compound treatment 1.06580803E8 1.4E7 0.72 9.9124759E7 7950000.0 0.43 0.8093 0.9696 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 I24 compound treatment 1.11336122E8 1.87E7 0.96 1.1105725E8 1.99E7 1.07 1.436 0.9985 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J01 compound treatment 1.13619243E8 2.1E7 1.08 1.20754771E8 2.96E7 1.59 1.888 0.9819 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J02 compound treatment 8.0065665E7 -1.25E7 -0.64 7.933378E7 -1.18E7 -0.64 -0.9053 -1.0 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J03 compound treatment 7.8257696E7 -1.43E7 -0.74 8.2621392E7 -8560000.0 -0.46 -0.8456 -0.9747 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J04 compound treatment 7.455257E7 -1.8E7 -0.92 7.3508633E7 -1.77E7 -0.95 -1.3269 -0.9999 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J05 mock treatment 9.5378571E7 2780000.0 0.14 9.5322292E7 4140000.0 0.22 0.2585 0.9765 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J06 mock treatment 9.0498582E7 -2100000.0 -0.11 9.1446229E7 268000.0 0.01 -0.0659 -0.6068 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J07 compound treatment 7.9118497E7 -1.35E7 -0.69 8.1860228E7 -9320000.0 -0.5 -0.8434 -0.9877 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J08 compound treatment 3.3014287E7 -5.96E7 -3.05 3.4448977E7 -5.67E7 -3.05 -4.3196 -1.0 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J09 compound treatment 6.8956907E7 -2.36E7 -1.21 7.1730644E7 -1.94E7 -1.05 -1.5974 -0.9974 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J10 compound treatment 3.0889856E7 -6.17E7 -3.16 3.6127046E7 -5.51E7 -2.96 -4.3327 -0.9995 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J11 compound treatment 7.867027E7 -1.39E7 -0.71 7.8831002E7 -1.23E7 -0.66 -0.975 -0.9994 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J12 compound treatment 6.5587319E7 -2.7E7 -1.38 6.5500589E7 -2.57E7 -1.38 -1.9567 -1.0 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J13 compound treatment 6.363166E7 -2.9E7 -1.48 6.8690222E7 -2.25E7 -1.21 -1.9061 -0.9949 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J14 compound treatment 6.6880853E7 -2.57E7 -1.32 6.6009645E7 -2.52E7 -1.36 -1.8904 -0.9999 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J15 compound treatment 7.0005705E7 -2.26E7 -1.16 6.7923822E7 -2.33E7 -1.25 -1.7043 -0.9992 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J16 compound treatment 6.2718006E7 -2.99E7 -1.53 6.1956186E7 -2.92E7 -1.57 -2.1957 -0.9999 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J17 compound treatment 8.248571E7 -1.01E7 -0.52 8.0934965E7 -1.02E7 -0.55 -0.7566 -0.9995 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J18 compound treatment 7.3547617E7 -1.91E7 -0.98 7.5661517E7 -1.55E7 -0.84 -1.2813 -0.997 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J19 compound treatment 7.7711544E7 -1.49E7 -0.76 7.8618464E7 -1.26E7 -0.68 -1.0178 -0.9982 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J20 compound treatment 6.3087957E7 -2.95E7 -1.51 6.3582321E7 -2.76E7 -1.49 -2.1203 -1.0 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J21 mock treatment 1.03189194E8 1.06E7 0.54 9.8832316E7 7650000.0 0.41 0.6752 0.9908 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J22 mock treatment 9.6390473E7 3790000.0 0.19 9.9880778E7 8700000.0 0.47 0.4688 0.924 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J23 compound treatment 9.6285105E7 3690000.0 0.19 9.3385299E7 2210000.0 0.12 0.2176 0.9751 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 J24 compound treatment 7.5091171E7 -1.75E7 -0.9 7.959104E7 -1.16E7 -0.62 -1.0757 -0.9842 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K01 compound treatment 1.03634144E8 1.1E7 0.57 1.0571886E8 1.45E7 0.78 0.9536 0.9872 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K02 compound treatment 9.9526668E7 6930000.0 0.36 9.5931273E7 4750000.0 0.26 0.432 0.9871 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K03 compound treatment 7.6595762E7 -1.6E7 -0.82 7.186034E7 -1.93E7 -1.04 -1.3156 -0.9931 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K04 compound treatment 9.0790751E7 -1810000.0 -0.09 9.009943E7 -1080000.0 -0.06 -0.1066 -0.9746 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K05 compound treatment 9.8122106E7 5520000.0 0.28 9.8405866E7 7230000.0 0.39 0.4754 0.9877 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K06 compound treatment 8.8116755E7 -4480000.0 -0.23 8.3508676E7 -7670000.0 -0.41 -0.4545 -0.9617 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K07 mock treatment 8.1692078E7 -1.09E7 -0.56 8.4806577E7 -6370000.0 -0.34 -0.6379 -0.9725 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K08 mock treatment 8.0006491E7 -1.26E7 -0.65 8.5265931E7 -5910000.0 -0.32 -0.6815 -0.947 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K09 compound treatment 6.2641228E7 -3.0E7 -1.54 6.72324E7 -2.39E7 -1.29 -1.9975 -0.9962 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K10 compound treatment 6.9668808E7 -2.29E7 -1.18 7.6407761E7 -1.48E7 -0.8 -1.3935 -0.9819 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K11 compound treatment 6.4835117E7 -2.78E7 -1.42 6.9462329E7 -2.17E7 -1.17 -1.8331 -0.9952 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K12 compound treatment 7.8006332E7 -1.46E7 -0.75 7.8351262E7 -1.28E7 -0.69 -1.0173 -0.9992 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K13 compound treatment 7.1509912E7 -2.11E7 -1.08 7.0785083E7 -2.04E7 -1.1 -1.5408 -1.0 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K14 compound treatment 7.9173728E7 -1.34E7 -0.69 7.6882502E7 -1.43E7 -0.77 -1.0309 -0.9984 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K15 mock treatment 8.343216E7 -9170000.0 -0.47 7.977075E7 -1.14E7 -0.61 -0.7666 -0.9912 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K16 mock treatment 8.2009163E7 -1.06E7 -0.54 8.2969487E7 -8210000.0 -0.44 -0.6964 -0.9948 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K17 compound treatment 7.5904387E7 -1.67E7 -0.86 8.2579777E7 -8600000.0 -0.46 -0.9325 -0.9584 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K18 compound treatment 9.1762552E7 -837000.0 -0.04 8.5499365E7 -5680000.0 -0.31 -0.2466 -0.7985 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K19 compound treatment 9.1340518E7 -1260000.0 -0.06 9.0730346E7 -447000.0 -0.02 -0.0627 -0.9098 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K20 compound treatment 9.4771547E7 2170000.0 0.11 9.6502066E7 5320000.0 0.29 0.2814 0.9151 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K21 compound treatment 9.8115444E7 5520000.0 0.28 9.3360129E7 2180000.0 0.12 0.283 0.9244 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K22 compound treatment 9.6606339E7 4010000.0 0.21 9.6922669E7 5740000.0 0.31 0.364 0.9802 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K23 mock treatment 1.01557095E8 8960000.0 0.46 9.5482304E7 4300000.0 0.23 0.4885 0.9499 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 K24 mock treatment 1.11340687E8 1.87E7 0.96 1.10204881E8 1.9E7 1.02 1.4037 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L01 compound treatment 9.3316835E7 717000.0 0.04 9.4758848E7 3580000.0 0.19 0.1623 0.827 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L02 compound treatment 8.7674208E7 -4930000.0 -0.25 8.7419489E7 -3760000.0 -0.2 -0.3216 -0.994 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L03 compound treatment 7.5390281E7 -1.72E7 -0.88 7.5316031E7 -1.59E7 -0.85 -1.2277 -0.9999 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L04 compound treatment 2.6015138E7 -6.66E7 -3.41 2.5425523E7 -6.58E7 -3.54 -4.9168 -0.9998 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L05 compound treatment 6.3935299E7 -2.87E7 -1.47 6.5641785E7 -2.55E7 -1.38 -2.0112 -0.9995 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L06 compound treatment 4.4519847E7 -4.81E7 -2.46 5.0712419E7 -4.05E7 -2.18 -3.2833 -0.9981 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L07 mock treatment 8.3627604E7 -8970000.0 -0.46 8.9853918E7 -1320000.0 -0.07 -0.3756 -0.8071 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L08 mock treatment 7.8652023E7 -1.39E7 -0.71 8.2501544E7 -8680000.0 -0.47 -0.8359 -0.9788 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L09 compound treatment 7.605848E7 -1.65E7 -0.85 7.8530626E7 -1.26E7 -0.68 -1.0811 -0.9941 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L10 compound treatment 2.5884114E7 -6.67E7 -3.42 2.5565061E7 -6.56E7 -3.53 -4.9163 -0.9999 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L11 compound treatment 7.3660554E7 -1.89E7 -0.97 7.6884911E7 -1.43E7 -0.77 -1.2306 -0.9934 1006359 PK04_181227 Cc1cccc[n+]1C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L12 compound treatment 2.8733296E7 -6.39E7 -3.27 2.9090507E7 -6.21E7 -3.34 -4.6788 -0.9999 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L13 compound treatment 7.7258524E7 -1.53E7 -0.79 7.4560742E7 -1.66E7 -0.89 -1.1887 -0.9979 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L14 compound treatment 3.7753351E7 -5.48E7 -2.81 3.3548057E7 -5.76E7 -3.1 -4.1821 -0.9988 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L15 mock treatment 8.1786517E7 -1.08E7 -0.55 8.0796537E7 -1.04E7 -0.56 -0.7872 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L16 mock treatment 8.465217E7 -7950000.0 -0.41 8.4495502E7 -6680000.0 -0.36 -0.5425 -0.9981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L17 compound treatment 6.3150686E7 -2.94E7 -1.51 6.3774524E7 -2.74E7 -1.48 -2.1107 -0.9999 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L18 compound treatment 2.613442E7 -6.65E7 -3.41 3.0127471E7 -6.11E7 -3.29 -4.7335 -0.9998 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L19 compound treatment 7.4572242E7 -1.8E7 -0.92 8.1536285E7 -9640000.0 -0.52 -1.0205 -0.9628 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L20 compound treatment 2.6121527E7 -6.65E7 -3.41 2.5637415E7 -6.55E7 -3.53 -4.9049 -0.9998 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L21 compound treatment 9.4018124E7 1420000.0 0.07 9.3703117E7 2530000.0 0.14 0.1476 0.9569 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L22 compound treatment 5.5844283E7 -3.68E7 -1.88 5.2543305E7 -3.86E7 -2.08 -2.8032 -0.9988 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L23 mock treatment 1.08957748E8 1.64E7 0.84 1.02351923E8 1.12E7 0.6 1.0183 0.9868 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 L24 mock treatment 1.14702525E8 2.21E7 1.13 1.02603631E8 1.14E7 0.62 1.2361 0.9589 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M01 compound treatment 1.03636228E8 1.1E7 0.57 1.0363947E8 1.25E7 0.67 0.8745 0.9964 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M02 compound treatment 6.2024646E7 -3.06E7 -1.57 5.6030425E7 -3.51E7 -1.89 -2.4464 -0.9956 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M03 compound treatment 7.0668437E7 -2.19E7 -1.12 7.4446103E7 -1.67E7 -0.9 -1.4319 -0.994 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M04 compound treatment 2.6223212E7 -6.64E7 -3.4 2.5797066E7 -6.54E7 -3.52 -4.8951 -0.9999 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M05 compound treatment 5.6794275E7 -3.58E7 -1.84 6.0022458E7 -3.12E7 -1.68 -2.484 -0.999 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M06 compound treatment 8.7939098E7 -4660000.0 -0.24 9.2786585E7 1610000.0 0.09 -0.1077 -0.4237 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M07 compound treatment 8.2156067E7 -1.04E7 -0.54 8.3732385E7 -7450000.0 -0.4 -0.662 -0.9899 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M08 compound treatment 6.5864376E7 -2.67E7 -1.37 7.1398621E7 -1.98E7 -1.07 -1.7221 -0.9922 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M09 mock treatment 7.5389153E7 -1.72E7 -0.88 8.5436518E7 -5740000.0 -0.31 -0.8424 -0.9012 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M10 mock treatment 7.2721355E7 -1.99E7 -1.02 7.9232202E7 -1.19E7 -0.64 -1.1753 -0.9754 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M11 compound treatment 5.2456711E7 -4.01E7 -2.06 5.4606739E7 -3.66E7 -1.97 -2.8474 -0.9998 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M12 compound treatment 7.7447463E7 -1.52E7 -0.78 7.6630109E7 -1.45E7 -0.78 -1.1031 -1.0 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M13 mock treatment 7.7593976E7 -1.5E7 -0.77 7.0494924E7 -2.07E7 -1.11 -1.3314 -0.9837 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M14 mock treatment 7.7637263E7 -1.5E7 -0.77 7.2701191E7 -1.85E7 -0.99 -1.2458 -0.9917 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M15 compound treatment 5.290908E7 -3.97E7 -2.03 5.223394E7 -3.89E7 -2.1 -2.9214 -0.9999 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M16 compound treatment 2.784622E7 -6.48E7 -3.32 3.0874133E7 -6.03E7 -3.25 -4.643 -0.9999 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M17 compound treatment 6.4602592E7 -2.8E7 -1.43 7.3125327E7 -1.81E7 -0.97 -1.7021 -0.982 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M18 compound treatment 7.0295996E7 -2.23E7 -1.14 6.9225591E7 -2.2E7 -1.18 -1.6442 -0.9999 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M19 compound treatment 7.6119325E7 -1.65E7 -0.84 7.6674189E7 -1.45E7 -0.78 -1.1495 -0.9992 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M20 compound treatment 5.5366735E7 -3.72E7 -1.91 5.7061978E7 -3.41E7 -1.84 -2.6484 -0.9998 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M21 compound treatment 9.0367641E7 -2230000.0 -0.11 8.7621327E7 -3560000.0 -0.19 -0.2163 -0.9697 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M22 compound treatment 9.0227637E7 -2370000.0 -0.12 9.2855977E7 1680000.0 0.09 -0.0221 -0.1457 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M23 compound treatment 7.8017374E7 -1.46E7 -0.75 7.7878486E7 -1.33E7 -0.72 -1.0349 -0.9998 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 M24 compound treatment 1.06469625E8 1.39E7 0.71 9.5759093E7 4580000.0 0.25 0.6771 0.8999 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N01 compound treatment 9.9273477E7 6670000.0 0.34 9.7635142E7 6460000.0 0.35 0.4877 1.0 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N02 compound treatment 1.02739278E8 1.01E7 0.52 1.02361844E8 1.12E7 0.6 0.7933 0.9973 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N03 compound treatment 6.4291481E7 -2.83E7 -1.45 7.7324465E7 -1.39E7 -0.75 -1.5534 -0.9522 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N04 compound treatment 2.6449492E7 -6.62E7 -3.39 2.5964961E7 -6.52E7 -3.51 -4.8806 -0.9998 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N05 compound treatment 8.3494227E7 -9110000.0 -0.47 8.881906E7 -2360000.0 -0.13 -0.4198 -0.868 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N06 compound treatment 6.7442005E7 -2.52E7 -1.29 8.1218767E7 -9960000.0 -0.54 -1.291 -0.9244 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N07 compound treatment 7.5901205E7 -1.67E7 -0.86 8.4675787E7 -6500000.0 -0.35 -0.8528 -0.9222 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N08 compound treatment 7.3979065E7 -1.86E7 -0.95 8.3085048E7 -8090000.0 -0.44 -0.983 -0.9369 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N09 mock treatment 8.0532493E7 -1.21E7 -0.62 8.1233109E7 -9940000.0 -0.54 -0.816 -0.9974 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N10 mock treatment 7.4448013E7 -1.82E7 -0.93 7.7082589E7 -1.41E7 -0.76 -1.1946 -0.9949 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N11 compound treatment 7.0520239E7 -2.21E7 -1.13 7.3181302E7 -1.8E7 -0.97 -1.4855 -0.997 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N12 compound treatment 7.8100276E7 -1.45E7 -0.74 7.8121381E7 -1.31E7 -0.7 -1.0226 -0.9996 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N13 mock treatment 8.069404E7 -1.19E7 -0.61 6.949975E7 -2.17E7 -1.17 -1.2569 -0.9542 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N14 mock treatment 8.0595587E7 -1.2E7 -0.62 7.8753722E7 -1.24E7 -0.67 -0.9081 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N15 compound treatment 8.3692388E7 -8910000.0 -0.46 7.7493766E7 -1.37E7 -0.74 -0.8439 -0.9735 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N16 compound treatment 8.1105756E7 -1.15E7 -0.59 7.7903951E7 -1.33E7 -0.71 -0.922 -0.9954 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N17 compound treatment 8.2890791E7 -9710000.0 -0.5 8.3477082E7 -7700000.0 -0.41 -0.6451 -0.9959 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N18 compound treatment 4.626267E7 -4.63E7 -2.37 4.6087772E7 -4.51E7 -2.43 -3.3963 -0.9999 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N19 compound treatment 6.8213143E7 -2.44E7 -1.25 6.9874314E7 -2.13E7 -1.15 -1.695 -0.9991 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N20 compound treatment 2.9591602E7 -6.3E7 -3.23 2.891242E7 -6.23E7 -3.35 -4.6544 -0.9998 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N21 compound treatment 8.0274622E7 -1.23E7 -0.63 7.4082617E7 -1.71E7 -0.92 -1.0976 -0.9831 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N22 compound treatment 4.1956722E7 -5.06E7 -2.6 5.1096331E7 -4.01E7 -2.16 -3.3616 -0.9958 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N23 compound treatment 9.2564425E7 -35400.0 0.0 8.2674527E7 -8500000.0 -0.46 -0.3251 -0.7099 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 N24 compound treatment 1.09069698E8 1.65E7 0.84 9.6557826E7 5380000.0 0.29 0.8017 0.8984 1004341 PK04_181276 c1ccc2cnccc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O01 compound treatment 1.0016879E8 7570000.0 0.39 1.00340528E8 9160000.0 0.49 0.6232 0.9929 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O02 compound treatment 4.4954942E7 -4.76E7 -2.44 4.6653811E7 -4.45E7 -2.4 -3.4221 -1.0 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O03 compound treatment 8.6752776E7 -5850000.0 -0.3 8.760746E7 -3570000.0 -0.19 -0.3479 -0.977 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O04 compound treatment 3.7324269E7 -5.53E7 -2.83 4.2927452E7 -4.83E7 -2.6 -3.8405 -0.9991 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O05 compound treatment 1.00846081E8 8250000.0 0.42 1.05005954E8 1.38E7 0.74 0.8254 0.964 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O06 compound treatment 3.7247225E7 -5.54E7 -2.84 4.1104231E7 -5.01E7 -2.7 -3.9128 -0.9997 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O07 compound treatment 2.8242067E7 -6.44E7 -3.3 2.8896575E7 -6.23E7 -3.35 -4.704 -1.0 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O08 compound treatment 3.0570546E7 -6.2E7 -3.18 3.605296E7 -5.51E7 -2.97 -4.3471 -0.9994 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O09 compound treatment 8.37923E7 -8810000.0 -0.45 9.1458878E7 281000.0 0.02 -0.3085 -0.683 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O10 compound treatment 7.7755162E7 -1.48E7 -0.76 7.9154447E7 -1.2E7 -0.65 -0.9958 -0.9968 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O11 mock treatment 7.5053817E7 -1.75E7 -0.9 8.311758E7 -8060000.0 -0.43 -0.9428 -0.9442 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O12 mock treatment 8.4072666E7 -8530000.0 -0.44 8.2115108E7 -9060000.0 -0.49 -0.6541 -0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O13 compound treatment 9.7115674E7 4520000.0 0.23 8.9127074E7 -2050000.0 -0.11 0.0856 0.3337 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O14 compound treatment 8.7658911E7 -4940000.0 -0.25 8.0224261E7 -1.1E7 -0.59 -0.5962 -0.9287 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O15 compound treatment 8.1812227E7 -1.08E7 -0.55 8.4969862E7 -6210000.0 -0.33 -0.6273 -0.971 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O16 compound treatment 8.2038089E7 -1.06E7 -0.54 8.853682E7 -2640000.0 -0.14 -0.4833 -0.8636 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O17 compound treatment 7.9388783E7 -1.32E7 -0.68 8.7005829E7 -4170000.0 -0.22 -0.6376 -0.8938 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O18 compound treatment 7.2654336E7 -1.99E7 -1.02 6.8254373E7 -2.29E7 -1.23 -1.5957 -0.9956 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O19 compound treatment 5.8112928E7 -3.45E7 -1.77 5.0752259E7 -4.04E7 -2.18 -2.7892 -0.9947 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O20 compound treatment 7.5127489E7 -1.75E7 -0.9 6.676649E7 -2.44E7 -1.31 -1.5628 -0.9825 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O21 compound treatment 1.00837669E8 8240000.0 0.42 9.8401674E7 7220000.0 0.39 0.5736 0.9992 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O22 compound treatment 1.0010052E8 7500000.0 0.38 8.7825988E7 -3350000.0 -0.18 0.1442 0.3395 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O23 compound treatment 9.8483972E7 5880000.0 0.3 8.9161477E7 -2020000.0 -0.11 0.1365 0.4258 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 O24 compound treatment 1.10584113E8 1.8E7 0.92 1.05319826E8 1.41E7 0.76 1.1903 0.9955 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P01 compound treatment 7.7000085E7 -1.56E7 -0.8 7.2777453E7 -1.84E7 -0.99 -1.266 -0.9943 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P02 compound treatment 1.01016361E8 8420000.0 0.43 9.8013632E7 6840000.0 0.37 0.5653 0.9969 1015751 PK04_181300 Cc1ccncc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P03 compound treatment 7.9493829E7 -1.31E7 -0.67 7.4610306E7 -1.66E7 -0.89 -1.1058 -0.9902 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P04 compound treatment 9.8065134E7 5470000.0 0.28 9.6005498E7 4830000.0 0.26 0.3819 0.9993 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P05 compound treatment 7.9510135E7 -1.31E7 -0.67 7.8321756E7 -1.29E7 -0.69 -0.9639 -0.9999 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P06 compound treatment 8.3861246E7 -8740000.0 -0.45 8.410521E7 -7070000.0 -0.38 -0.586 -0.9967 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P07 compound treatment 3.9335494E7 -5.33E7 -2.73 5.0444098E7 -4.07E7 -2.19 -3.4814 -0.9941 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P08 compound treatment 7.7780142E7 -1.48E7 -0.76 7.8540698E7 -1.26E7 -0.68 -1.0183 -0.9985 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P09 compound treatment 8.1155097E7 -1.14E7 -0.59 8.0425781E7 -1.08E7 -0.58 -0.8242 -1.0 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P10 compound treatment 7.5625768E7 -1.7E7 -0.87 7.6497512E7 -1.47E7 -0.79 -1.1742 -0.9989 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P11 mock treatment 7.416416E7 -1.84E7 -0.94 7.6772621E7 -1.44E7 -0.78 -1.2167 -0.9952 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P12 mock treatment 7.42876E7 -1.83E7 -0.94 7.1427078E7 -1.98E7 -1.06 -1.4157 -0.9981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P13 compound treatment 7.5386942E7 -1.72E7 -0.88 6.6813443E7 -2.44E7 -1.31 -1.5516 -0.9813 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P14 compound treatment 8.1099511E7 -1.15E7 -0.59 7.3901158E7 -1.73E7 -0.93 -1.0747 -0.9757 1009497 PK04_181310 Cc1cc[n+](C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P15 compound treatment 5.4484317E7 -3.81E7 -1.95 5.9135374E7 -3.2E7 -1.73 -2.6015 -0.9981 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P16 compound treatment 8.608771E7 -6510000.0 -0.33 7.8095225E7 -1.31E7 -0.7 -0.7342 -0.9418 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P17 compound treatment 7.3219042E7 -1.94E7 -0.99 6.620439E7 -2.5E7 -1.34 -1.6533 -0.9889 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P18 compound treatment 8.8101637E7 -4500000.0 -0.23 8.1507312E7 -9670000.0 -0.52 -0.5313 -0.9328 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P19 compound treatment 9.0646203E7 -1950000.0 -0.1 8.2525219E7 -8650000.0 -0.47 -0.4003 -0.8399 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P20 compound treatment 9.3781151E7 1180000.0 0.06 8.4900785E7 -6280000.0 -0.34 -0.1962 -0.5714 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P21 compound treatment 9.3373516E7 774000.0 0.04 7.9285158E7 -1.19E7 -0.64 -0.4248 -0.6621 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P22 compound treatment 9.7479586E7 4880000.0 0.25 8.5096972E7 -6080000.0 -0.33 -0.0547 -0.1328 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P23 compound treatment 1.04102274E8 1.15E7 0.59 9.4728212E7 3550000.0 0.19 0.5521 0.8908 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2181 P24 compound treatment 1.12855064E8 2.03E7 1.04 1.04021856E8 1.28E7 0.69 1.2231 0.9805 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A01 compound treatment 7.0408829E7 -2.66E7 -1.36 7.0763903E7 -3.35E7 -1.8 -2.2363 -0.9904 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A02 compound treatment 1.15144563E8 1.82E7 0.93 1.18159167E8 1.39E7 0.75 1.1897 0.9942 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A03 compound treatment 1.19351589E8 2.24E7 1.15 1.1628303E8 1.21E7 0.65 1.2707 0.9637 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A04 compound treatment 1.32508237E8 3.55E7 1.82 1.37416831E8 3.32E7 1.79 2.5523 1.0 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A05 compound treatment 1.18873549E8 2.19E7 1.12 1.1453255E8 1.03E7 0.56 1.1868 0.9473 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A06 compound treatment 1.06436978E8 9470000.0 0.49 1.00815713E8 -3400000.0 -0.18 0.2137 0.4118 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A07 compound treatment 1.29883926E8 3.29E7 1.69 1.27202706E8 2.3E7 1.24 2.0683 0.9884 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A08 compound treatment 1.18991347E8 2.2E7 1.13 1.13460137E8 9240000.0 0.5 1.1502 0.9322 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A09 compound treatment 9.360806E7 -3350000.0 -0.17 6.5696634E7 -3.85E7 -2.07 -1.5885 -0.7631 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A10 compound treatment 1.15238229E8 1.83E7 0.94 1.10461647E8 6240000.0 0.34 0.9 0.9044 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A11 compound treatment 1.1639461E8 1.94E7 1.0 1.14459954E8 1.02E7 0.55 1.0942 0.9611 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A12 compound treatment 1.10620651E8 1.37E7 0.7 1.10836516E8 6620000.0 0.36 0.7469 0.9509 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A13 mock treatment 1.20090413E8 2.31E7 1.19 1.31176026E8 2.7E7 1.45 1.8646 0.9949 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A14 mock treatment 1.1194801E8 1.5E7 0.77 1.09719543E8 5500000.0 0.3 0.7525 0.9142 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A15 compound treatment 1.13346508E8 1.64E7 0.84 1.11300071E8 7080000.0 0.38 0.8634 0.9362 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A16 compound treatment 1.12918898E8 1.6E7 0.82 1.15599857E8 1.14E7 0.61 1.0116 0.9899 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A17 compound treatment 1.14876581E8 1.79E7 0.92 1.1037268E8 6150000.0 0.33 0.8835 0.9052 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A18 compound treatment 1.26037597E8 2.91E7 1.49 1.28063802E8 2.38E7 1.28 1.9616 0.9973 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A19 compound treatment 1.27793321E8 3.08E7 1.58 1.21798859E8 1.76E7 0.95 1.7867 0.97 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A20 compound treatment 1.1662743E8 1.97E7 1.01 1.14037038E8 9820000.0 0.53 1.0865 0.9547 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A21 compound treatment 1.08426707E8 1.15E7 0.59 1.05095545E8 876000.0 0.05 0.4488 0.7614 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A22 compound treatment 1.14093931E8 1.71E7 0.88 1.14138231E8 9920000.0 0.53 0.9985 0.9716 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A23 compound treatment 1.22967843E8 2.6E7 1.33 1.18477202E8 1.43E7 0.77 1.4854 0.9657 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 A24 compound treatment 1.28416994E8 3.15E7 1.61 1.32301356E8 2.81E7 1.51 2.2092 0.9995 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B01 compound treatment 1.29402923E8 3.24E7 1.66 1.30929528E8 2.67E7 1.44 2.1927 0.9974 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B02 compound treatment 9.7356141E7 394000.0 0.02 8.7276653E7 -1.69E7 -0.91 -0.6309 -0.6913 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B03 compound treatment 9.1749363E7 -5210000.0 -0.27 9.4791691E7 -9430000.0 -0.51 -0.5479 -0.9551 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B04 compound treatment 1.03055504E8 6090000.0 0.31 1.00605115E8 -3610000.0 -0.19 0.0832 0.226 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B05 compound treatment 9.1461784E7 -5500000.0 -0.28 9.3158719E7 -1.11E7 -0.6 -0.6205 -0.9416 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B06 compound treatment 7.364712E7 -2.33E7 -1.19 5.888198E7 -4.53E7 -2.44 -2.5714 -0.946 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B07 compound treatment 1.0326743E8 6300000.0 0.32 1.12631074E8 8410000.0 0.45 0.5488 0.9863 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B08 compound treatment 1.05137862E8 8180000.0 0.42 1.1174701E8 7530000.0 0.41 0.5829 0.9999 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B09 compound treatment 8.9119618E7 -7840000.0 -0.4 1.00953795E8 -3270000.0 -0.18 -0.4086 -0.9313 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B10 compound treatment 1.01648082E8 4690000.0 0.24 1.09197488E8 4980000.0 0.27 0.3593 0.9985 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B11 compound treatment 8.3859676E7 -1.31E7 -0.67 8.2235236E7 -2.2E7 -1.18 -1.312 -0.9639 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B12 compound treatment 9.9025252E7 2060000.0 0.11 1.07450403E8 3230000.0 0.17 0.1978 0.9715 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B13 mock treatment 1.01991789E8 5030000.0 0.26 9.9226361E7 -4990000.0 -0.27 -0.0079 -0.0212 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B14 mock treatment 1.02415826E8 5450000.0 0.28 1.01225405E8 -2990000.0 -0.16 0.0836 0.2591 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B15 compound treatment 9.7802243E7 840000.0 0.04 9.8002897E7 -6220000.0 -0.33 -0.2063 -0.6112 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B16 compound treatment 9.768937E7 727000.0 0.04 1.03715437E8 -504000.0 -0.03 0.0071 0.1548 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B17 compound treatment 9.677665E7 -186000.0 -0.01 9.159071E7 -1.26E7 -0.68 -0.4876 -0.7169 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B18 compound treatment 1.0191609E8 4950000.0 0.25 9.3481936E7 -1.07E7 -0.58 -0.2294 -0.3632 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B19 compound treatment 9.5405357E7 -1560000.0 -0.08 8.8700344E7 -1.55E7 -0.84 -0.6474 -0.7711 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B20 compound treatment 1.14937157E8 1.8E7 0.92 1.18603168E8 1.44E7 0.77 1.1991 0.9963 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B21 compound treatment 1.03547394E8 6580000.0 0.34 9.8053789E7 -6170000.0 -0.33 0.0038 0.0081 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B22 compound treatment 1.11372308E8 1.44E7 0.74 1.07901607E8 3680000.0 0.2 0.6624 0.8663 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B23 compound treatment 1.12677176E8 1.57E7 0.81 1.11421175E8 7200000.0 0.39 0.8437 0.9439 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 B24 compound treatment 1.22928091E8 2.6E7 1.33 1.19513034E8 1.53E7 0.82 1.5234 0.9734 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C01 compound treatment 1.15672144E8 1.87E7 0.96 1.15026677E8 1.08E7 0.58 1.0896 0.9714 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C02 compound treatment 9.5170864E7 -1790000.0 -0.09 1.00713139E8 -3510000.0 -0.19 -0.1985 -0.9451 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C03 compound treatment 1.01451257E8 4490000.0 0.23 1.08340297E8 4120000.0 0.22 0.3196 0.9998 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C04 compound treatment 7.2996551E7 -2.4E7 -1.23 7.6511875E7 -2.77E7 -1.49 -1.9236 -0.9953 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C05 compound treatment 8.947088E7 -7490000.0 -0.38 1.0102277E8 -3200000.0 -0.17 -0.3932 -0.9345 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C06 compound treatment 9.3578141E7 -3380000.0 -0.17 1.01007697E8 -3210000.0 -0.17 -0.245 -1.0 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C07 compound treatment 9.5425071E7 -1540000.0 -0.08 9.7941467E7 -6280000.0 -0.34 -0.2948 -0.8492 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C08 compound treatment 9.3465168E7 -3500000.0 -0.18 1.00495323E8 -3720000.0 -0.2 -0.2686 -0.9984 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C09 compound treatment 1.04999107E8 8040000.0 0.41 1.06624963E8 2410000.0 0.13 0.3828 0.8867 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C10 compound treatment 1.02189582E8 5230000.0 0.27 1.05819482E8 1600000.0 0.09 0.2503 0.8896 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C11 mock treatment 1.02447829E8 5490000.0 0.28 1.14222834E8 1.0E7 0.54 0.5797 0.954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C12 mock treatment 9.6184137E7 -778000.0 -0.04 1.01507718E8 -2710000.0 -0.15 -0.1315 -0.8685 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C13 compound treatment 8.5947552E7 -1.1E7 -0.56 9.1880493E7 -1.23E7 -0.66 -0.8691 -0.9967 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C14 compound treatment 9.1466753E7 -5500000.0 -0.28 8.7264778E7 -1.7E7 -0.91 -0.8448 -0.8841 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C15 mock treatment 9.7814087E7 851000.0 0.04 9.7968771E7 -6250000.0 -0.34 -0.2072 -0.6103 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C16 mock treatment 9.7828684E7 866000.0 0.04 9.4314966E7 -9900000.0 -0.53 -0.3458 -0.646 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C17 compound treatment 9.3964798E7 -3000000.0 -0.15 8.8989775E7 -1.52E7 -0.82 -0.6886 -0.8252 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C18 compound treatment 9.9578067E7 2620000.0 0.13 9.6542571E7 -7680000.0 -0.41 -0.1975 -0.4545 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C19 compound treatment 2.7565072E7 -6.94E7 -3.56 2.6859527E7 -7.74E7 -4.17 -5.4608 -0.9969 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C20 compound treatment 9.8770768E7 1810000.0 0.09 9.838699E7 -5830000.0 -0.31 -0.1566 -0.4781 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C21 compound treatment 1.03123231E8 6160000.0 0.32 1.02319291E8 -1900000.0 -0.1 0.1509 0.4546 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C22 compound treatment 9.8843949E7 1880000.0 0.1 1.03428176E8 -792000.0 -0.04 0.038 0.3608 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C23 compound treatment 1.1638998E8 1.94E7 1.0 1.12752297E8 8530000.0 0.46 1.029 0.9383 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 C24 compound treatment 8.3304729E7 -1.37E7 -0.7 8.8299811E7 -1.59E7 -0.86 -1.1012 -0.9949 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D01 compound treatment 1.1173602E8 1.48E7 0.76 1.11832972E8 7610000.0 0.41 0.8253 0.9585 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D02 compound treatment 2.744862E7 -6.95E7 -3.56 2.7017662E7 -7.72E7 -4.16 -5.459 -0.997 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D03 compound treatment 9.3876419E7 -3090000.0 -0.16 1.05641681E8 1420000.0 0.08 -0.0577 -0.3284 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D04 compound treatment 8.4439387E7 -1.25E7 -0.64 9.6598555E7 -7620000.0 -0.41 -0.7441 -0.9767 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D05 compound treatment 9.2100884E7 -4860000.0 -0.25 1.01792057E8 -2430000.0 -0.13 -0.2686 -0.9547 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D06 compound treatment 8.2374809E7 -1.46E7 -0.75 8.3349262E7 -2.09E7 -1.12 -1.3234 -0.9804 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D07 compound treatment 8.0323192E7 -1.66E7 -0.85 9.067418E7 -1.35E7 -0.73 -1.1188 -0.997 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D08 compound treatment 8.9562322E7 -7400000.0 -0.38 9.914554E7 -5070000.0 -0.27 -0.4614 -0.9871 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D09 compound treatment 8.5761372E7 -1.12E7 -0.57 9.7659254E7 -6560000.0 -0.35 -0.6558 -0.9728 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D10 compound treatment 9.2748537E7 -4210000.0 -0.22 9.8164331E7 -6060000.0 -0.33 -0.3833 -0.98 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D11 mock treatment 9.417906E7 -2780000.0 -0.14 9.9418972E7 -4800000.0 -0.26 -0.2837 -0.9607 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D12 mock treatment 1.02641922E8 5680000.0 0.29 1.12541396E8 8320000.0 0.45 0.5227 0.9782 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D13 compound treatment 9.4683091E7 -2280000.0 -0.12 9.6234341E7 -7990000.0 -0.43 -0.3867 -0.8678 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D14 compound treatment 9.0077676E7 -6880000.0 -0.35 9.2087215E7 -1.21E7 -0.65 -0.7115 -0.9582 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D15 mock treatment 9.3030798E7 -3930000.0 -0.2 1.04353966E8 134000.0 0.01 -0.1374 -0.6813 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D16 mock treatment 1.04675777E8 7710000.0 0.4 1.09152215E8 4930000.0 0.27 0.4674 0.9813 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D17 compound treatment 8.1114806E7 -1.58E7 -0.81 9.064337E7 -1.36E7 -0.73 -1.0913 -0.9986 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D18 compound treatment 8.7683986E7 -9280000.0 -0.48 9.9876671E7 -4340000.0 -0.23 -0.5016 -0.9466 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D19 compound treatment 8.9657971E7 -7300000.0 -0.37 9.7002347E7 -7220000.0 -0.39 -0.5396 -0.9998 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D20 compound treatment 9.789172E7 929000.0 0.05 9.9332316E7 -4890000.0 -0.26 -0.1524 -0.5699 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D21 compound treatment 9.6414118E7 -548000.0 -0.03 9.4360734E7 -9860000.0 -0.53 -0.3953 -0.7435 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D22 compound treatment 7.5030848E7 -2.19E7 -1.12 7.8923635E7 -2.53E7 -1.36 -1.7581 -0.9954 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D23 compound treatment 1.04179505E8 7220000.0 0.37 1.10201198E8 5980000.0 0.32 0.4893 0.9976 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 D24 compound treatment 1.16491898E8 1.95E7 1.0 1.28727974E8 2.45E7 1.32 1.641 0.9907 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E01 mock treatment 1.12262662E8 1.53E7 0.78 1.08159602E8 3940000.0 0.21 0.7045 0.8672 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E02 mock treatment 1.06483697E8 9520000.0 0.49 1.08238299E8 4020000.0 0.22 0.4981 0.9331 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E03 mock treatment 1.11066735E8 1.41E7 0.72 1.17420749E8 1.32E7 0.71 1.0138 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E04 compound treatment 9.3024631E7 -3940000.0 -0.2 1.05655995E8 1440000.0 0.08 -0.088 -0.4073 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E05 compound treatment 1.00473268E8 3510000.0 0.18 1.18247055E8 1.4E7 0.76 0.6614 0.8517 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E06 compound treatment 1.03618371E8 6660000.0 0.34 1.0822536E8 4010000.0 0.22 0.3937 0.9756 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E07 compound treatment 9.0909469E7 -6050000.0 -0.31 1.03572301E8 -647000.0 -0.03 -0.244 -0.7817 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E08 compound treatment 3.4245563E7 -6.27E7 -3.21 3.775982E7 -6.65E7 -3.58 -4.8036 -0.9986 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E09 mock treatment 9.4576438E7 -2390000.0 -0.12 1.02846115E8 -1370000.0 -0.07 -0.1388 -0.971 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E10 mock treatment 9.3405196E7 -3560000.0 -0.18 1.06880807E8 2660000.0 0.14 -0.0276 -0.119 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E11 compound treatment 8.6721744E7 -1.02E7 -0.52 1.01932588E8 -2290000.0 -0.12 -0.4582 -0.85 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E12 compound treatment 9.4438612E7 -2520000.0 -0.13 9.6083652E7 -8140000.0 -0.44 -0.4013 -0.8784 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E13 compound treatment 6.422057E7 -3.27E7 -1.68 6.305553E7 -4.12E7 -2.22 -2.7541 -0.9906 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E14 compound treatment 9.662823E7 -334000.0 -0.02 1.03678909E8 -541000.0 -0.03 -0.0327 -0.968 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E15 compound treatment 7.0182941E7 -2.68E7 -1.37 7.3803369E7 -3.04E7 -1.64 -2.1287 -0.9961 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E16 compound treatment 8.7895918E7 -9070000.0 -0.46 8.6919088E7 -1.73E7 -0.93 -0.9874 -0.9484 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E17 mock treatment 1.02849806E8 5890000.0 0.3 1.08633718E8 4410000.0 0.24 0.3814 0.993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E18 mock treatment 1.03041516E8 6080000.0 0.31 1.1111849E8 6900000.0 0.37 0.483 0.9962 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E19 compound treatment 1.01087504E8 4120000.0 0.21 1.1006988E8 5850000.0 0.32 0.3723 0.9812 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E20 compound treatment 1.07119265E8 1.02E7 0.52 1.10280149E8 6060000.0 0.33 0.5989 0.9747 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E21 compound treatment 9.9226638E7 2260000.0 0.12 1.01583904E8 -2640000.0 -0.14 -0.0183 -0.0999 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E22 compound treatment 1.10609819E8 1.36E7 0.7 1.15528794E8 1.13E7 0.61 0.9252 0.9976 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E23 compound treatment 5.4459385E7 -4.25E7 -2.18 5.5128023E7 -4.91E7 -2.64 -3.4097 -0.9954 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 E24 compound treatment 1.1209358E8 1.51E7 0.78 1.15306583E8 1.11E7 0.6 0.9705 0.9917 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F01 mock treatment 1.16095113E8 1.91E7 0.98 1.11644403E8 7420000.0 0.4 0.9761 0.9217 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F02 mock treatment 1.10442685E8 1.35E7 0.69 1.14792614E8 1.06E7 0.57 0.8911 0.9954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F03 compound treatment 9.9386099E7 2420000.0 0.12 1.05678086E8 1460000.0 0.08 0.1434 0.9755 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F04 compound treatment 1.02241516E8 5280000.0 0.27 1.04977624E8 758000.0 0.04 0.2202 0.8047 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F05 compound treatment 9.7608054E7 645000.0 0.03 1.06846362E8 2630000.0 0.14 0.1234 0.8496 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F06 compound treatment 9.9035278E7 2070000.0 0.11 1.08446046E8 4230000.0 0.23 0.236 0.9398 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F07 compound treatment 1.04782514E8 7820000.0 0.4 1.12247218E8 8030000.0 0.43 0.5891 0.9993 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F08 compound treatment 9.091086E7 -6050000.0 -0.31 1.00249019E8 -3970000.0 -0.21 -0.3705 -0.9835 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F09 mock treatment 1.01385949E8 4420000.0 0.23 1.06419415E8 2200000.0 0.12 0.2441 0.9542 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F10 mock treatment 9.7276962E7 314000.0 0.02 1.03150544E8 -1070000.0 -0.06 -0.0293 -0.4904 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F11 compound treatment 9.9384904E7 2420000.0 0.12 1.06123441E8 1900000.0 0.1 0.1603 0.9955 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F12 compound treatment 9.6543287E7 -419000.0 -0.02 1.05063193E8 843000.0 0.05 0.0169 0.3367 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F13 compound treatment 9.5857837E7 -1100000.0 -0.06 1.068527E8 2630000.0 0.14 0.0602 0.3944 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F14 compound treatment 9.9960512E7 3000000.0 0.15 1.07834999E8 3620000.0 0.19 0.2463 0.9931 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F15 compound treatment 9.5190865E7 -1770000.0 -0.09 1.04178365E8 -41400.0 0.0 -0.0658 -0.7243 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F16 compound treatment 8.9739658E7 -7220000.0 -0.37 1.00906806E8 -3310000.0 -0.18 -0.3879 -0.944 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F17 mock treatment 9.7465934E7 503000.0 0.03 1.07821744E8 3600000.0 0.19 0.1554 0.7942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F18 mock treatment 9.8970221E7 2010000.0 0.1 1.07387834E8 3170000.0 0.17 0.1934 0.9707 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F19 compound treatment 9.8419276E7 1460000.0 0.07 1.05736219E8 1520000.0 0.08 0.1105 0.999 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F20 compound treatment 9.269199E7 -4270000.0 -0.22 9.8659513E7 -5560000.0 -0.3 -0.3665 -0.9881 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F21 compound treatment 9.8006457E7 1040000.0 0.05 1.04671212E8 451000.0 0.02 0.055 0.9363 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F22 compound treatment 6.9886514E7 -2.71E7 -1.39 7.4096162E7 -3.01E7 -1.62 -2.1283 -0.997 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F23 compound treatment 1.00678551E8 3720000.0 0.19 9.88135E7 -5410000.0 -0.29 -0.0712 -0.2046 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 F24 compound treatment 1.23518376E8 2.66E7 1.36 1.29589421E8 2.54E7 1.37 1.9284 1.0 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G01 compound treatment 7.6842E7 -2.01E7 -1.03 6.7688648E7 -3.65E7 -1.97 -2.1202 -0.9546 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G02 compound treatment 1.0874105E8 1.18E7 0.6 1.03216434E8 -1000000.0 -0.05 0.3887 0.6413 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G03 mock treatment 1.11478072E8 1.45E7 0.74 1.14466619E8 1.02E7 0.55 0.9162 0.9892 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G04 mock treatment 1.02780742E8 5820000.0 0.3 1.1201099E8 7790000.0 0.42 0.5075 0.986 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G05 compound treatment 6.8008064E7 -2.9E7 -1.48 6.9304313E7 -3.49E7 -1.88 -2.3789 -0.9931 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G06 compound treatment 1.05248507E8 8290000.0 0.42 1.12497588E8 8280000.0 0.45 0.6155 0.9997 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G07 compound treatment 1.03333367E8 6370000.0 0.33 1.11982989E8 7760000.0 0.42 0.5265 0.9925 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G08 compound treatment 8.7988342E7 -8970000.0 -0.46 9.6666533E7 -7550000.0 -0.41 -0.6129 -0.9981 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G09 compound treatment 6.3649847E7 -3.33E7 -1.71 6.8312544E7 -3.59E7 -1.93 -2.5746 -0.9981 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G10 compound treatment 8.2859447E7 -1.41E7 -0.72 8.9789563E7 -1.44E7 -0.78 -1.0606 -0.9993 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G11 compound treatment 8.9390347E7 -7570000.0 -0.39 1.04475666E8 256000.0 0.01 -0.2647 -0.6816 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G12 compound treatment 8.584467E7 -1.11E7 -0.57 1.01278654E8 -2940000.0 -0.16 -0.5149 -0.8706 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G13 compound treatment 9.5643296E7 -1320000.0 -0.07 1.08628656E8 4410000.0 0.24 0.1201 0.4864 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G14 compound treatment 8.657677E7 -1.04E7 -0.53 1.00959325E8 -3260000.0 -0.18 -0.5005 -0.893 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G15 compound treatment 9.5071573E7 -1890000.0 -0.1 1.08787383E8 4570000.0 0.25 0.1054 0.3987 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G16 compound treatment 8.4243324E7 -1.27E7 -0.65 9.4194504E7 -1.0E7 -0.54 -0.8427 -0.9956 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G17 compound treatment 9.4030001E7 -2930000.0 -0.15 1.03973089E8 -247000.0 -0.01 -0.1157 -0.7666 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G18 compound treatment 9.1816057E7 -5150000.0 -0.26 9.916314E7 -5060000.0 -0.27 -0.3791 -0.9999 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G19 mock treatment 9.4976565E7 -1990000.0 -0.1 1.03894351E8 -325000.0 -0.02 -0.0844 -0.8168 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G20 mock treatment 1.05660581E8 8700000.0 0.45 1.05981323E8 1760000.0 0.09 0.3823 0.8388 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G21 compound treatment 1.02095373E8 5130000.0 0.26 1.06068484E8 1850000.0 0.1 0.2564 0.9116 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G22 compound treatment 9.3951266E7 -3010000.0 -0.15 1.05873347E8 1650000.0 0.09 -0.0462 -0.2591 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G23 compound treatment 2.8409792E7 -6.86E7 -3.51 2.7512016E7 -7.67E7 -4.13 -5.4053 -0.9968 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 G24 compound treatment 8.8429572E7 -8530000.0 -0.44 1.02345214E8 -1870000.0 -0.1 -0.3806 -0.848 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H01 compound treatment 1.04437171E8 7470000.0 0.38 1.00235884E8 -3980000.0 -0.21 0.1192 0.2714 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H02 compound treatment 9.7008875E7 46300.0 0.0 9.6753397E7 -7470000.0 -0.4 -0.2826 -0.7029 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H03 mock treatment 1.07228346E8 1.03E7 0.53 1.14599895E8 1.04E7 0.56 0.7673 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H04 mock treatment 1.00788555E8 3830000.0 0.2 1.01780096E8 -2440000.0 -0.13 0.0458 0.1939 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H05 compound treatment 9.7758848E7 796000.0 0.04 9.8229101E7 -5990000.0 -0.32 -0.1993 -0.6128 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H06 compound treatment 1.05090943E8 8130000.0 0.42 1.13073409E8 8850000.0 0.48 0.6317 0.9977 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H07 compound treatment 1.0034489E8 3380000.0 0.17 1.08738031E8 4520000.0 0.24 0.2946 0.9862 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H08 compound treatment 9.3110933E7 -3850000.0 -0.2 1.01136383E8 -3080000.0 -0.17 -0.257 -0.9963 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H09 compound treatment 9.7356594E7 394000.0 0.02 1.02286325E8 -1930000.0 -0.1 -0.0593 -0.5595 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H10 compound treatment 9.1114675E7 -5850000.0 -0.3 1.03633035E8 -587000.0 -0.03 -0.2343 -0.7773 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H11 compound treatment 9.0166254E7 -6800000.0 -0.35 1.00747674E8 -3470000.0 -0.19 -0.3785 -0.9575 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H12 compound treatment 9.5759373E7 -1200000.0 -0.06 1.10227914E8 6010000.0 0.32 0.1852 0.5622 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H13 compound treatment 8.9938274E7 -7020000.0 -0.36 1.04339244E8 119000.0 0.01 -0.25 -0.6944 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H14 compound treatment 8.8350881E7 -8610000.0 -0.44 1.00729469E8 -3490000.0 -0.19 -0.445 -0.9276 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H15 compound treatment 8.9846822E7 -7120000.0 -0.36 1.00696787E8 -3520000.0 -0.19 -0.392 -0.9536 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H16 compound treatment 8.631684E7 -1.06E7 -0.55 1.02304241E8 -1920000.0 -0.1 -0.4588 -0.8262 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H17 compound treatment 9.7249946E7 287000.0 0.01 1.06110144E8 1890000.0 0.1 0.0824 0.8011 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H18 compound treatment 8.4222255E7 -1.27E7 -0.65 9.4948385E7 -9270000.0 -0.5 -0.8148 -0.9912 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H19 mock treatment 1.01211286E8 4250000.0 0.22 1.07743057E8 3520000.0 0.19 0.2881 0.9976 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H20 mock treatment 9.561262E7 -1350000.0 -0.07 1.04682223E8 462000.0 0.02 -0.0313 -0.4259 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H21 compound treatment 9.2063475E7 -4900000.0 -0.25 1.04421125E8 201000.0 0.01 -0.1699 -0.6759 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H22 compound treatment 8.6221235E7 -1.07E7 -0.55 1.01884929E8 -2330000.0 -0.13 -0.4782 -0.8468 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H23 compound treatment 1.08268716E8 1.13E7 0.58 1.09564732E8 5340000.0 0.29 0.6133 0.9478 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 H24 compound treatment 9.2463564E7 -4500000.0 -0.23 9.9549996E7 -4670000.0 -0.25 -0.3409 -0.9991 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I01 compound treatment 1.07367909E8 1.04E7 0.53 1.04504235E8 284000.0 0.02 0.3879 0.7271 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I02 compound treatment 9.6842506E7 -120000.0 -0.01 1.06292897E8 2070000.0 0.11 0.0746 0.6671 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I03 compound treatment 1.10028861E8 1.31E7 0.67 1.13538666E8 9320000.0 0.5 0.8284 0.9899 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I04 compound treatment 8.8453191E7 -8510000.0 -0.44 9.3240323E7 -1.1E7 -0.59 -0.7265 -0.9888 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I05 mock treatment 9.7437074E7 474000.0 0.02 1.07321152E8 3100000.0 0.17 0.1353 0.8016 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I06 mock treatment 9.8906258E7 1940000.0 0.1 1.06578346E8 2360000.0 0.13 0.1603 0.9928 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I07 compound treatment 5.5566747E7 -4.14E7 -2.12 6.0259553E7 -4.4E7 -2.37 -3.1742 -0.9985 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I08 compound treatment 8.0999504E7 -1.6E7 -0.82 8.4645115E7 -1.96E7 -1.05 -1.3239 -0.9922 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I09 compound treatment 7.6339052E7 -2.06E7 -1.06 8.2762434E7 -2.15E7 -1.16 -1.5645 -0.999 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I10 compound treatment 8.7828058E7 -9130000.0 -0.47 9.7369289E7 -6850000.0 -0.37 -0.5919 -0.993 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I11 compound treatment 9.0304057E7 -6660000.0 -0.34 1.0693953E8 2720000.0 0.15 -0.1377 -0.3709 BCB03_000168 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I12 compound treatment 6.6719254E7 -3.02E7 -1.55 7.8248482E7 -2.6E7 -1.4 -2.085 -0.9987 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I13 compound treatment 2.6881454E7 -7.01E7 -3.59 2.6685913E7 -7.75E7 -4.18 -5.4922 -0.9972 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I14 compound treatment 7.8539725E7 -1.84E7 -0.94 9.212355E7 -1.21E7 -0.65 -1.1283 -0.9836 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I15 compound treatment 9.5898886E7 -1060000.0 -0.05 1.06329419E8 2110000.0 0.11 0.0418 0.3316 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I16 compound treatment 7.5860815E7 -2.11E7 -1.08 8.4912252E7 -1.93E7 -1.04 -1.4999 -0.9998 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I17 compound treatment 9.2049098E7 -4910000.0 -0.25 1.04010838E8 -209000.0 -0.01 -0.186 -0.738 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I18 compound treatment 8.2100514E7 -1.49E7 -0.76 9.2175048E7 -1.2E7 -0.65 -0.9973 -0.9968 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I19 compound treatment 3.8406929E7 -5.86E7 -3.0 4.6644814E7 -5.76E7 -3.1 -4.3145 -0.9999 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I20 compound treatment 9.1646704E7 -5320000.0 -0.27 9.8434524E7 -5790000.0 -0.31 -0.4129 -0.9978 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I21 mock treatment 9.6943816E7 -18800.0 0.0 1.0521121E8 991000.0 0.05 0.0371 0.6943 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I22 mock treatment 9.7502402E7 540000.0 0.03 1.04706794E8 487000.0 0.03 0.0381 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I23 compound treatment 1.02185369E8 5220000.0 0.27 1.09217057E8 5000000.0 0.27 0.3796 1.0 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 I24 compound treatment 1.13791566E8 1.68E7 0.86 1.20088017E8 1.59E7 0.85 1.2141 1.0 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J01 compound treatment 1.09752588E8 1.28E7 0.66 1.0809119E8 3870000.0 0.21 0.6109 0.8882 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J02 compound treatment 9.9902054E7 2940000.0 0.15 1.04824631E8 605000.0 0.03 0.1296 0.8406 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J03 compound treatment 1.01939152E8 4980000.0 0.26 1.10960842E8 6740000.0 0.36 0.437 0.9851 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J04 compound treatment 1.03915637E8 6950000.0 0.36 1.08414269E8 4190000.0 0.23 0.4117 0.9758 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J05 mock treatment 1.03031353E8 6070000.0 0.31 1.0953859E8 5320000.0 0.29 0.4225 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J06 mock treatment 1.00385301E8 3420000.0 0.18 1.09696841E8 5480000.0 0.29 0.3326 0.9692 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J07 compound treatment 9.628168E7 -681000.0 -0.03 1.05375481E8 1160000.0 0.06 0.0193 0.2709 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J08 compound treatment 2.6848898E7 -7.01E7 -3.59 2.7056374E7 -7.72E7 -4.16 -5.4792 -0.9974 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J09 compound treatment 9.7171668E7 209000.0 0.01 1.07656618E8 3440000.0 0.19 0.1384 0.7468 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J10 compound treatment 8.7262065E7 -9700000.0 -0.5 1.02231777E8 -1990000.0 -0.11 -0.4273 -0.8401 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J11 compound treatment 9.2579157E7 -4380000.0 -0.22 1.03341327E8 -878000.0 -0.05 -0.1923 -0.8376 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J12 compound treatment 9.4871523E7 -2090000.0 -0.11 1.0689889E8 2680000.0 0.14 0.0262 0.146 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J13 compound treatment 8.8651819E7 -8310000.0 -0.43 1.02172282E8 -2050000.0 -0.11 -0.3792 -0.8617 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J14 compound treatment 8.2160765E7 -1.48E7 -0.76 9.5280579E7 -8940000.0 -0.48 -0.8768 -0.9759 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J15 compound treatment 8.804507E7 -8920000.0 -0.46 9.8351983E7 -5870000.0 -0.32 -0.5466 -0.9838 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J16 compound treatment 8.1792177E7 -1.52E7 -0.78 9.1536298E7 -1.27E7 -0.68 -1.0328 -0.9979 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J17 compound treatment 7.5517451E7 -2.14E7 -1.1 8.3255475E7 -2.1E7 -1.13 -1.5755 -0.9999 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J18 compound treatment 9.3397765E7 -3560000.0 -0.18 1.01326511E8 -2890000.0 -0.16 -0.2394 -0.9969 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J19 compound treatment 8.3517612E7 -1.34E7 -0.69 8.8479633E7 -1.57E7 -0.85 -1.0866 -0.9947 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J20 compound treatment 8.7193506E7 -9770000.0 -0.5 9.1593767E7 -1.26E7 -0.68 -0.8348 -0.9887 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J21 mock treatment 9.5978258E7 -984000.0 -0.05 1.01768851E8 -2450000.0 -0.13 -0.129 -0.913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J22 mock treatment 9.5732495E7 -1230000.0 -0.06 1.03280308E8 -939000.0 -0.05 -0.0804 -0.994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J23 compound treatment 1.03567891E8 6610000.0 0.34 1.04711097E8 491000.0 0.03 0.2581 0.7601 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 J24 compound treatment 1.07323924E8 1.04E7 0.53 1.22416954E8 1.82E7 0.98 1.0684 0.9586 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K01 compound treatment 1.11609923E8 1.46E7 0.75 1.06405054E8 2190000.0 0.12 0.614 0.8081 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K02 compound treatment 9.0646021E7 -6320000.0 -0.32 8.7490868E7 -1.67E7 -0.9 -0.8659 -0.9046 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K03 compound treatment 1.03651768E8 6690000.0 0.34 1.06736235E8 2520000.0 0.14 0.3382 0.9175 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K04 compound treatment 5.3398264E7 -4.36E7 -2.23 5.2957618E7 -5.13E7 -2.76 -3.5308 -0.9945 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K05 compound treatment 2.8419554E7 -6.85E7 -3.51 2.9165285E7 -7.51E7 -4.04 -5.342 -0.9976 1107217 BCB03_000204 Cc1cccnc1I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K06 compound treatment 8.5352974E7 -1.16E7 -0.6 9.088908E7 -1.33E7 -0.72 -0.9284 -0.9957 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K07 mock treatment 9.5451573E7 -1510000.0 -0.08 1.07230618E8 3010000.0 0.16 0.0599 0.3333 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K08 mock treatment 9.0354226E7 -6610000.0 -0.34 9.9212549E7 -5010000.0 -0.27 -0.4302 -0.9936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K09 compound treatment 9.3093874E7 -3870000.0 -0.2 1.00033674E8 -4190000.0 -0.23 -0.2996 -0.998 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K10 compound treatment 4.5195041E7 -5.18E7 -2.65 7.7019768E7 -2.72E7 -1.46 -2.9118 -0.9608 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K11 compound treatment 9.8653343E7 1690000.0 0.09 1.09650525E8 5430000.0 0.29 0.2681 0.8789 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K12 compound treatment 7.1721692E7 -2.52E7 -1.29 8.0818425E7 -2.34E7 -1.26 -1.8058 -0.9999 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K13 compound treatment 8.8119585E7 -8840000.0 -0.45 1.02178588E8 -2040000.0 -0.11 -0.3982 -0.8538 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K14 compound treatment 7.8996519E7 -1.8E7 -0.92 9.0271307E7 -1.39E7 -0.75 -1.1822 -0.9949 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K15 mock treatment 8.77831E7 -9180000.0 -0.47 9.8229015E7 -5990000.0 -0.32 -0.5608 -0.9831 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K16 mock treatment 8.5078273E7 -1.19E7 -0.61 9.711116E7 -7110000.0 -0.38 -0.7014 -0.9749 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K17 compound treatment 9.2999717E7 -3960000.0 -0.2 1.04804034E8 584000.0 0.03 -0.1214 -0.5905 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K18 compound treatment 8.1549824E7 -1.54E7 -0.79 8.4867792E7 -1.94E7 -1.04 -1.2955 -0.9907 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K19 compound treatment 9.3428365E7 -3530000.0 -0.18 1.02178331E8 -2040000.0 -0.11 -0.2058 -0.9714 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K20 compound treatment 8.7518618E7 -9440000.0 -0.48 9.3603488E7 -1.06E7 -0.57 -0.7465 -0.9966 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K21 compound treatment 9.7233186E7 271000.0 0.01 1.02756861E8 -1460000.0 -0.08 -0.0459 -0.5738 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K22 compound treatment 8.8672138E7 -8290000.0 -0.42 8.8198545E7 -1.6E7 -0.86 -0.9105 -0.9468 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K23 mock treatment 9.9298465E7 2340000.0 0.12 1.03132945E8 -1090000.0 -0.06 0.0433 0.3247 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 K24 mock treatment 1.07021343E8 1.01E7 0.52 1.13632725E8 9410000.0 0.51 0.723 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L01 compound treatment 9.6908549E7 -54000.0 0.0 9.2624902E7 -1.16E7 -0.62 -0.4435 -0.7102 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L02 compound treatment 8.5795026E7 -1.12E7 -0.57 8.2783966E7 -2.14E7 -1.15 -1.221 -0.9476 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L03 compound treatment 9.6573358E7 -389000.0 -0.02 1.00351712E8 -3870000.0 -0.21 -0.1614 -0.7713 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L04 compound treatment 9.1188037E7 -5770000.0 -0.3 9.5269248E7 -8950000.0 -0.48 -0.5501 -0.9726 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L05 compound treatment 1.00492892E8 3530000.0 0.18 1.07783988E8 3560000.0 0.19 0.2637 0.9996 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L06 compound treatment 7.1723111E7 -2.52E7 -1.29 7.8185503E7 -2.6E7 -1.4 -1.906 -0.9992 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L07 mock treatment 9.4009052E7 -2950000.0 -0.15 1.02747362E8 -1470000.0 -0.08 -0.1631 -0.9545 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L08 mock treatment 8.8545446E7 -8420000.0 -0.43 9.6279491E7 -7940000.0 -0.43 -0.6074 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L09 compound treatment 8.7892741E7 -9070000.0 -0.46 9.7583244E7 -6640000.0 -0.36 -0.5814 -0.9916 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L10 compound treatment 8.7866144E7 -9100000.0 -0.47 1.02295797E8 -1920000.0 -0.1 -0.4029 -0.8437 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L11 compound treatment 8.3908892E7 -1.31E7 -0.67 1.00247051E8 -3970000.0 -0.21 -0.6244 -0.8889 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L12 compound treatment 6.5004933E7 -3.2E7 -1.64 7.6610369E7 -2.76E7 -1.49 -2.2095 -0.9988 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L13 compound treatment 8.3496387E7 -1.35E7 -0.69 9.7991636E7 -6230000.0 -0.34 -0.7252 -0.945 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L14 compound treatment 4.7570358E7 -4.94E7 -2.53 6.0176256E7 -4.4E7 -2.37 -3.4671 -0.9995 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L15 mock treatment 8.2224353E7 -1.47E7 -0.76 9.7627056E7 -6590000.0 -0.36 -0.7852 -0.9407 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L16 mock treatment 8.0755832E7 -1.62E7 -0.83 9.8636213E7 -5580000.0 -0.3 -0.8 -0.9056 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L17 compound treatment 9.2871336E7 -4090000.0 -0.21 1.00218808E8 -4000000.0 -0.22 -0.3006 -0.9999 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L18 compound treatment 8.1936508E7 -1.5E7 -0.77 9.0620674E7 -1.36E7 -0.73 -1.0624 -0.9997 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L19 compound treatment 9.2334236E7 -4630000.0 -0.24 1.01427864E8 -2790000.0 -0.15 -0.274 -0.9758 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L20 compound treatment 5.5510509E7 -4.15E7 -2.12 6.0861442E7 -4.34E7 -2.33 -3.1533 -0.9989 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L21 compound treatment 9.0812179E7 -6150000.0 -0.32 9.6814221E7 -7410000.0 -0.4 -0.5049 -0.9932 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L22 compound treatment 9.5226754E7 -1740000.0 -0.09 9.6071661E7 -8150000.0 -0.44 -0.3732 -0.8335 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L23 mock treatment 9.9046639E7 2080000.0 0.11 1.01965447E8 -2250000.0 -0.12 -0.0103 -0.0638 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 L24 mock treatment 1.08056364E8 1.11E7 0.57 1.14737062E8 1.05E7 0.57 0.8025 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M01 compound treatment 1.17938146E8 2.1E7 1.08 1.23295738E8 1.91E7 1.03 1.4866 0.9997 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M02 compound treatment 7.7120954E7 -1.98E7 -1.02 7.3788426E7 -3.04E7 -1.64 -1.8779 -0.9737 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M03 compound treatment 1.04692694E8 7730000.0 0.4 1.10659647E8 6440000.0 0.35 0.5254 0.9978 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M04 compound treatment 1.0716103E8 1.02E7 0.52 1.07146591E8 2930000.0 0.16 0.481 0.8811 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M05 compound treatment 1.0080138E8 3840000.0 0.2 1.04893422E8 674000.0 0.04 0.1648 0.8236 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M06 compound treatment 7.5102424E7 -2.19E7 -1.12 8.5272422E7 -1.89E7 -1.02 -1.5137 -0.9989 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M07 compound treatment 9.3173005E7 -3790000.0 -0.19 1.06623055E8 2400000.0 0.13 -0.0458 -0.1963 3000956 BCB03_000242 CCCc1cccc(=O)o1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M08 compound treatment 7.1506027E7 -2.55E7 -1.3 7.579439E7 -2.84E7 -1.53 -2.005 -0.9968 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M09 mock treatment 9.0130616E7 -6830000.0 -0.35 1.02853294E8 -1370000.0 -0.07 -0.2996 -0.8374 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M10 mock treatment 8.5987953E7 -1.1E7 -0.56 1.02227451E8 -1990000.0 -0.11 -0.4736 -0.8271 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M11 compound treatment 8.6186927E7 -1.08E7 -0.55 9.4843712E7 -9380000.0 -0.5 -0.7475 -0.999 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M12 compound treatment 8.4476465E7 -1.25E7 -0.64 9.4855899E7 -9360000.0 -0.5 -0.8091 -0.993 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M13 mock treatment 8.8676472E7 -8290000.0 -0.42 9.5034868E7 -9180000.0 -0.49 -0.65 -0.9971 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M14 mock treatment 8.2193718E7 -1.48E7 -0.76 9.7939418E7 -6280000.0 -0.34 -0.7744 -0.9341 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M15 compound treatment 7.9753441E7 -1.72E7 -0.88 9.7452734E7 -6770000.0 -0.36 -0.8814 -0.9235 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M16 compound treatment 4.7671417E7 -4.93E7 -2.53 5.591268E7 -4.83E7 -2.6 -3.6258 -0.9999 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M17 compound treatment 8.7234403E7 -9730000.0 -0.5 9.9425011E7 -4790000.0 -0.26 -0.5351 -0.9531 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M18 compound treatment 4.8540363E7 -4.84E7 -2.48 5.723803E7 -4.7E7 -2.53 -3.5439 -1.0 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M19 compound treatment 9.1621761E7 -5340000.0 -0.27 9.6062203E7 -8160000.0 -0.44 -0.5042 -0.9741 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M20 compound treatment 8.6041063E7 -1.09E7 -0.56 9.4184608E7 -1.0E7 -0.54 -0.7779 -0.9998 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M21 compound treatment 9.8927363E7 1960000.0 0.1 1.0324219E8 -978000.0 -0.05 0.034 0.299 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M22 compound treatment 5.2105199E7 -4.49E7 -2.3 5.3061216E7 -5.12E7 -2.75 -3.5737 -0.996 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M23 compound treatment 1.06358123E8 9400000.0 0.48 1.07950612E8 3730000.0 0.2 0.4826 0.9249 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 M24 compound treatment 7.4271085E7 -2.27E7 -1.16 7.3963695E7 -3.03E7 -1.63 -1.9745 -0.9863 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N01 compound treatment 7.9533234E7 -1.74E7 -0.89 8.1322154E7 -2.29E7 -1.23 -1.5036 -0.9875 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N02 compound treatment 1.06207242E8 9240000.0 0.47 1.12588532E8 8370000.0 0.45 0.6537 0.9997 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N03 compound treatment 7.2384306E7 -2.46E7 -1.26 8.540849E7 -1.88E7 -1.01 -1.607 -0.9942 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N04 compound treatment 8.8614955E7 -8350000.0 -0.43 9.4825646E7 -9390000.0 -0.51 -0.6602 -0.9965 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N05 compound treatment 7.7806865E7 -1.92E7 -0.98 8.8516423E7 -1.57E7 -0.85 -1.2922 -0.9972 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N06 compound treatment 4.6203922E7 -5.08E7 -2.6 5.2796747E7 -5.14E7 -2.77 -3.7977 -0.9995 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N07 compound treatment 8.8392589E7 -8570000.0 -0.44 9.4368191E7 -9850000.0 -0.53 -0.6857 -0.9956 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N08 compound treatment 6.8002304E7 -2.9E7 -1.48 8.4680719E7 -1.95E7 -1.05 -1.7936 -0.9858 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N09 mock treatment 8.4982438E7 -1.2E7 -0.61 9.6427136E7 -7790000.0 -0.42 -0.7309 -0.9828 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N10 mock treatment 7.8707297E7 -1.83E7 -0.94 9.3654219E7 -1.06E7 -0.57 -1.0639 -0.9716 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N11 compound treatment 7.5415123E7 -2.15E7 -1.1 9.2707709E7 -1.15E7 -0.62 -1.2193 -0.9627 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N12 compound treatment 7.8729653E7 -1.82E7 -0.93 9.6295546E7 -7920000.0 -0.43 -0.9625 -0.9369 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N13 mock treatment 8.1752228E7 -1.52E7 -0.78 9.6104271E7 -8120000.0 -0.44 -0.8603 -0.9626 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N14 mock treatment 7.8655054E7 -1.83E7 -0.94 9.3771736E7 -1.04E7 -0.56 -1.0613 -0.9701 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N15 compound treatment 7.6628056E7 -2.03E7 -1.04 9.4074789E7 -1.01E7 -0.55 -1.1232 -0.9546 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N16 compound treatment 8.8109659E7 -8850000.0 -0.45 1.00724468E8 -3500000.0 -0.19 -0.4539 -0.9241 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N17 compound treatment 1.07058241E8 1.01E7 0.52 1.24918892E8 2.07E7 1.11 1.1541 0.9391 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N18 compound treatment 8.1371065E7 -1.56E7 -0.8 9.4656266E7 -9560000.0 -0.52 -0.9292 -0.9774 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N19 compound treatment 8.8973005E7 -7990000.0 -0.41 1.04097356E8 -122000.0 -0.01 -0.2942 -0.7184 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N20 compound treatment 8.1998933E7 -1.5E7 -0.77 8.6782871E7 -1.74E7 -0.94 -1.2063 -0.995 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N21 compound treatment 9.1085268E7 -5880000.0 -0.3 1.03556118E8 -664000.0 -0.04 -0.2383 -0.7855 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N22 compound treatment 9.0815033E7 -6150000.0 -0.32 9.1884504E7 -1.23E7 -0.66 -0.6925 -0.9419 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N23 compound treatment 1.00037503E8 3070000.0 0.16 9.589507E7 -8320000.0 -0.45 -0.2056 -0.4326 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 N24 compound treatment 1.10666344E8 1.37E7 0.7 1.10893776E8 6670000.0 0.36 0.7508 0.9516 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O01 compound treatment 7.2225236E7 -2.47E7 -1.27 7.4538235E7 -2.97E7 -1.6 -2.0267 -0.9934 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O02 compound treatment 8.0344933E7 -1.66E7 -0.85 8.4072923E7 -2.01E7 -1.08 -1.3694 -0.9928 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O03 compound treatment 9.3554674E7 -3410000.0 -0.17 9.8584962E7 -5630000.0 -0.3 -0.3381 -0.9656 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O04 compound treatment 6.7968401E7 -2.9E7 -1.49 7.366759E7 -3.06E7 -1.65 -2.2142 -0.9987 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O05 compound treatment 8.6482055E7 -1.05E7 -0.54 9.7449874E7 -6770000.0 -0.36 -0.6376 -0.9822 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O06 compound treatment 9.0435999E7 -6530000.0 -0.33 9.5931134E7 -8290000.0 -0.45 -0.5521 -0.9899 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O07 compound treatment 7.2176607E7 -2.48E7 -1.27 8.5992332E7 -1.82E7 -0.98 -1.5923 -0.9919 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O08 compound treatment 7.0340626E7 -2.66E7 -1.36 7.4600601E7 -2.96E7 -1.6 -2.0927 -0.997 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O09 compound treatment 7.8971622E7 -1.8E7 -0.92 8.5806908E7 -1.84E7 -0.99 -1.3531 -0.9993 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O10 compound treatment 8.0709001E7 -1.63E7 -0.83 9.0602346E7 -1.36E7 -0.73 -1.1076 -0.998 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O11 mock treatment 7.67858E7 -2.02E7 -1.03 8.8675371E7 -1.55E7 -0.84 -1.3231 -0.9945 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O12 mock treatment 8.3971013E7 -1.3E7 -0.67 1.0166243E8 -2560000.0 -0.14 -0.5682 -0.8357 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O13 compound treatment 7.9136752E7 -1.78E7 -0.91 9.0410337E7 -1.38E7 -0.74 -1.1719 -0.9948 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O14 compound treatment 7.7547316E7 -1.94E7 -1.0 9.7750076E7 -6470000.0 -0.35 -0.95 -0.901 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O15 compound treatment 7.9190874E7 -1.78E7 -0.91 9.3348667E7 -1.09E7 -0.59 -1.058 -0.9772 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O16 compound treatment 7.3504756E7 -2.35E7 -1.2 9.1530907E7 -1.27E7 -0.68 -1.3333 -0.9641 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O17 compound treatment 6.6823617E7 -3.01E7 -1.54 8.0898412E7 -2.33E7 -1.26 -1.9803 -0.9947 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O18 compound treatment 8.2693558E7 -1.43E7 -0.73 9.5228888E7 -8990000.0 -0.48 -0.8595 -0.9799 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O19 compound treatment 6.6663709E7 -3.03E7 -1.55 7.2241096E7 -3.2E7 -1.72 -2.3158 -0.9987 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O20 compound treatment 8.1463586E7 -1.55E7 -0.79 8.6867619E7 -1.74E7 -0.93 -1.2224 -0.9967 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O21 compound treatment 9.98507E7 2890000.0 0.15 1.02789965E8 -1430000.0 -0.08 0.0502 0.301 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O22 compound treatment 9.8675656E7 1710000.0 0.09 9.3277752E7 -1.09E7 -0.59 -0.3546 -0.5952 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O23 compound treatment 9.6604359E7 -358000.0 -0.02 9.6993268E7 -7230000.0 -0.39 -0.2882 -0.7396 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 O24 compound treatment 1.13789713E8 1.68E7 0.86 1.13727205E8 9510000.0 0.51 0.9719 0.969 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P01 compound treatment 1.09608109E8 1.26E7 0.65 1.1690003E8 1.27E7 0.68 0.9411 0.9997 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P02 compound treatment 1.05893013E8 8930000.0 0.46 1.06551697E8 2330000.0 0.13 0.4124 0.869 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P03 compound treatment 8.0436799E7 -1.65E7 -0.85 8.6438837E7 -1.78E7 -0.96 -1.276 -0.9981 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P04 compound treatment 8.4083946E7 -1.29E7 -0.66 8.9743198E7 -1.45E7 -0.78 -1.018 -0.9966 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P05 compound treatment 8.3823414E7 -1.31E7 -0.67 8.8827875E7 -1.54E7 -0.83 -1.0623 -0.9947 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P06 compound treatment 8.0882713E7 -1.61E7 -0.82 9.2154577E7 -1.21E7 -0.65 -1.0422 -0.9931 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P07 compound treatment 6.7480709E7 -2.95E7 -1.51 9.355898E7 -1.07E7 -0.57 -1.4744 -0.9121 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P08 compound treatment 6.0063342E7 -3.69E7 -1.89 6.444006E7 -3.98E7 -2.14 -2.852 -0.9981 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P09 compound treatment 9.3600148E7 -3360000.0 -0.17 1.00232169E8 -3990000.0 -0.21 -0.2737 -0.9941 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P10 compound treatment 9.2376973E7 -4590000.0 -0.24 1.07352772E8 3130000.0 0.17 -0.0469 -0.1621 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P11 mock treatment 8.8216168E7 -8750000.0 -0.45 9.3950425E7 -1.03E7 -0.55 -0.708 -0.9946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P12 mock treatment 8.8659943E7 -8300000.0 -0.43 1.05797271E8 1580000.0 0.08 -0.2408 -0.555 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P13 compound treatment 5.8176387E7 -3.88E7 -1.99 7.6830518E7 -2.74E7 -1.47 -2.4486 -0.9892 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P14 compound treatment 7.8357011E7 -1.86E7 -0.95 9.0240675E7 -1.4E7 -0.75 -1.2066 -0.9931 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P15 compound treatment 7.1114097E7 -2.58E7 -1.32 8.2954124E7 -2.13E7 -1.15 -1.7465 -0.9974 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P16 compound treatment 8.5429182E7 -1.15E7 -0.59 9.4570889E7 -9650000.0 -0.52 -0.7854 -0.9979 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P17 compound treatment 8.3171595E7 -1.38E7 -0.71 9.4164244E7 -1.01E7 -0.54 -0.8827 -0.9913 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P18 compound treatment 6.9457099E7 -2.75E7 -1.41 7.4231975E7 -3.0E7 -1.61 -2.1387 -0.9977 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P19 compound treatment 8.9427076E7 -7540000.0 -0.39 9.1343432E7 -1.29E7 -0.69 -0.7634 -0.9618 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P20 compound treatment 8.7844516E7 -9120000.0 -0.47 8.8236131E7 -1.6E7 -0.86 -0.9391 -0.9588 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P21 compound treatment 3.880985E7 -5.82E7 -2.98 3.3165582E7 -7.11E7 -3.83 -4.8131 -0.9924 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P22 compound treatment 1.05146055E8 8180000.0 0.42 9.8265456E7 -5950000.0 -0.32 0.0698 0.1323 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P23 compound treatment 1.11398573E8 1.44E7 0.74 1.08911382E8 4690000.0 0.25 0.7018 0.8977 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2281 P24 compound treatment 7.6339001E7 -2.06E7 -1.06 5.9380274E7 -4.48E7 -2.41 -2.4548 -0.9313 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A01 compound treatment 9.8299245E7 410000.0 0.02 1.00209398E8 8400000.0 0.45 0.3346 0.7392 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A02 compound treatment 1.17711776E8 1.98E7 1.02 1.0746678E8 1.57E7 0.84 1.3145 0.9957 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A03 compound treatment 1.24704435E8 2.68E7 1.37 1.08706996E8 1.69E7 0.91 1.6152 0.9799 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A04 compound treatment 1.25012824E8 2.71E7 1.39 1.15453259E8 2.36E7 1.27 1.8832 0.999 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A05 compound treatment 1.21952398E8 2.41E7 1.23 1.0541289E8 1.36E7 0.73 1.39 0.969 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A06 compound treatment 9.631431E7 -1570000.0 -0.08 8.1409382E7 -1.04E7 -0.56 -0.4532 -0.8007 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A07 compound treatment 1.17754527E8 1.99E7 1.02 1.02070396E8 1.03E7 0.55 1.1106 0.9587 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A08 compound treatment 9.1308741E7 -6580000.0 -0.34 6.9053237E7 -2.28E7 -1.23 -1.1051 -0.8694 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A09 compound treatment 1.16166376E8 1.83E7 0.94 9.8552316E7 6740000.0 0.36 0.9191 0.9148 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A10 compound treatment 1.09898605E8 1.2E7 0.62 9.6283058E7 4470000.0 0.24 0.6055 0.9161 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A11 compound treatment 9.8143494E7 255000.0 0.01 8.745083E7 -4360000.0 -0.23 -0.1568 -0.6668 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A12 compound treatment 1.02922777E8 5030000.0 0.26 8.3880244E7 -7930000.0 -0.43 -0.1196 -0.2396 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A13 mock treatment 1.05021469E8 7130000.0 0.37 9.2976151E7 1160000.0 0.06 0.3028 0.8165 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A14 mock treatment 1.01377932E8 3490000.0 0.18 8.1285784E7 -1.05E7 -0.57 -0.2744 -0.4616 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A15 compound treatment 1.14159117E8 1.63E7 0.83 9.3175159E7 1360000.0 0.07 0.6416 0.7664 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A16 compound treatment 9.1587299E7 -6300000.0 -0.32 8.6169958E7 -5640000.0 -0.3 -0.4432 -0.9995 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A17 compound treatment 1.05424733E8 7540000.0 0.39 9.3303931E7 1490000.0 0.08 0.3299 0.8363 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A18 compound treatment 1.08732284E8 1.08E7 0.56 1.01671455E8 9860000.0 0.53 0.7684 0.9997 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A19 compound treatment 9.9873901E7 1980000.0 0.1 8.9885819E7 -1930000.0 -0.1 -0.0014 -0.0096 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A20 compound treatment 9.4767141E7 -3120000.0 -0.16 8.9835526E7 -1980000.0 -0.11 -0.1884 -0.9804 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A21 compound treatment 1.00276432E8 2390000.0 0.12 9.2608571E7 797000.0 0.04 0.1169 0.9013 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A22 compound treatment 1.05387212E8 7500000.0 0.38 9.8937631E7 7130000.0 0.38 0.5431 1.0 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A23 compound treatment 1.07033368E8 9140000.0 0.47 1.0027402E8 8460000.0 0.46 0.6536 0.9999 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 A24 compound treatment 1.18607149E8 2.07E7 1.06 1.11665379E8 1.99E7 1.07 1.5069 1.0 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B01 compound treatment 7.9448752E7 -1.84E7 -0.95 6.8145662E7 -2.37E7 -1.27 -1.5694 -0.9892 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B02 compound treatment 8.3768475E7 -1.41E7 -0.72 7.5129558E7 -1.67E7 -0.9 -1.147 -0.9943 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B03 compound treatment 9.2470841E7 -5420000.0 -0.28 8.829745E7 -3510000.0 -0.19 -0.3302 -0.9825 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B04 compound treatment 8.5655445E7 -1.22E7 -0.63 8.0744677E7 -1.11E7 -0.6 -0.8648 -0.9997 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B05 compound treatment 1.03081972E8 5190000.0 0.27 9.83036E7 6490000.0 0.35 0.4354 0.9909 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B06 compound treatment 9.1072701E7 -6820000.0 -0.35 7.7558073E7 -1.43E7 -0.77 -0.7898 -0.9365 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B07 compound treatment 9.7947899E7 59000.0 0.0 9.3826685E7 2020000.0 0.11 0.0789 0.7265 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B08 compound treatment 9.2266217E7 -5620000.0 -0.29 8.2644309E7 -9170000.0 -0.49 -0.5528 -0.9672 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B09 compound treatment 9.2682474E7 -5210000.0 -0.27 8.9433393E7 -2380000.0 -0.13 -0.2792 -0.9434 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B10 compound treatment 7.4291842E7 -2.36E7 -1.21 6.7024333E7 -2.48E7 -1.33 -1.799 -0.9988 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B11 compound treatment 8.7385793E7 -1.05E7 -0.54 6.9945304E7 -2.19E7 -1.18 -1.2133 -0.9371 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B12 compound treatment 2.8676829E7 -6.92E7 -3.55 3.0325132E7 -6.15E7 -3.31 -4.8496 -0.9994 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B13 mock treatment 9.0380396E7 -7510000.0 -0.38 7.4991838E7 -1.68E7 -0.91 -0.9126 -0.9273 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B14 mock treatment 8.9157111E7 -8730000.0 -0.45 7.4268147E7 -1.75E7 -0.94 -0.9845 -0.9417 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B15 compound treatment 8.1614253E7 -1.63E7 -0.83 6.8513885E7 -2.33E7 -1.25 -1.4769 -0.9803 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B16 compound treatment 2.593512E7 -7.2E7 -3.69 2.5408153E7 -6.64E7 -3.58 -5.1362 -0.9999 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B17 compound treatment 8.3870597E7 -1.4E7 -0.72 7.43902E7 -1.74E7 -0.94 -1.1714 -0.9913 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B18 compound treatment 7.4207695E7 -2.37E7 -1.21 5.8136894E7 -3.37E7 -1.81 -2.1405 -0.9809 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B19 compound treatment 8.764646E7 -1.02E7 -0.52 7.7287773E7 -1.45E7 -0.78 -0.9242 -0.9812 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B20 compound treatment 9.7287742E7 -601000.0 -0.03 9.355515E7 1740000.0 0.09 0.0446 0.4514 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B21 compound treatment 9.1852088E7 -6040000.0 -0.31 8.4354364E7 -7460000.0 -0.4 -0.5027 -0.9917 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B22 compound treatment 8.9865314E7 -8020000.0 -0.41 8.8154447E7 -3660000.0 -0.2 -0.43 -0.9432 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B23 compound treatment 1.02274535E8 4390000.0 0.22 9.7335915E7 5520000.0 0.3 0.3693 0.9904 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 B24 compound treatment 1.12645657E8 1.48E7 0.76 1.06928127E8 1.51E7 0.81 1.1104 0.9993 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C01 compound treatment 1.23670592E8 2.58E7 1.32 1.11154146E8 1.93E7 1.04 1.6709 0.9931 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C02 compound treatment 1.05377355E8 7490000.0 0.38 9.7339025E7 5530000.0 0.3 0.4819 0.9921 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C03 compound treatment 1.04616541E8 6730000.0 0.34 9.7314888E7 5500000.0 0.3 0.4534 0.9972 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C04 compound treatment 1.03595816E8 5710000.0 0.29 9.5532391E7 3720000.0 0.2 0.3485 0.983 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C05 compound treatment 9.9617333E7 1730000.0 0.09 9.8726604E7 6920000.0 0.37 0.326 0.8516 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C06 compound treatment 9.8076058E7 187000.0 0.01 9.8109143E7 6300000.0 0.34 0.2466 0.7268 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C07 compound treatment 9.8248794E7 360000.0 0.02 9.3280725E7 1470000.0 0.08 0.069 0.8492 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C08 compound treatment 9.6444456E7 -1440000.0 -0.07 8.8923729E7 -2890000.0 -0.16 -0.1623 -0.9424 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C09 compound treatment 1.0894129E8 1.11E7 0.57 9.9637843E7 7830000.0 0.42 0.6986 0.9894 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C10 compound treatment 1.02781572E8 4890000.0 0.25 9.1740415E7 -71000.0 0.0 0.1746 0.6962 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C11 mock treatment 1.00943463E8 3050000.0 0.16 9.1485638E7 -326000.0 -0.02 0.0983 0.624 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C12 mock treatment 8.9205771E7 -8680000.0 -0.45 8.1231799E7 -1.06E7 -0.57 -0.7175 -0.9925 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C13 compound treatment 8.2660632E7 -1.52E7 -0.78 7.6342936E7 -1.55E7 -0.83 -1.1409 -0.9995 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C14 compound treatment 8.543747E7 -1.25E7 -0.64 7.4414653E7 -1.74E7 -0.94 -1.1137 -0.9825 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C15 mock treatment 8.5291947E7 -1.26E7 -0.65 7.2354459E7 -1.95E7 -1.05 -1.1974 -0.9729 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C16 mock treatment 7.877686E7 -1.91E7 -0.98 6.8399952E7 -2.34E7 -1.26 -1.5841 -0.9922 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C17 compound treatment 8.6737505E7 -1.12E7 -0.57 8.5257235E7 -6550000.0 -0.35 -0.6537 -0.9732 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C18 compound treatment 8.1901147E7 -1.6E7 -0.82 7.8314227E7 -1.35E7 -0.73 -1.0934 -0.9982 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C19 compound treatment 8.3970835E7 -1.39E7 -0.71 8.1444553E7 -1.04E7 -0.56 -0.8992 -0.9926 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C20 compound treatment 9.1153564E7 -6740000.0 -0.35 8.4100951E7 -7710000.0 -0.42 -0.5377 -0.9958 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C21 compound treatment 8.9410522E7 -8480000.0 -0.43 8.8366236E7 -3450000.0 -0.19 -0.4385 -0.928 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C22 compound treatment 9.2767124E7 -5120000.0 -0.26 8.8452753E7 -3360000.0 -0.18 -0.3135 -0.9835 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C23 compound treatment 8.1003977E7 -1.69E7 -0.87 6.2145612E7 -2.97E7 -1.6 -1.7416 -0.9585 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 C24 compound treatment 1.09791177E8 1.19E7 0.61 1.0905957E8 1.72E7 0.93 1.0881 0.9792 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D01 compound treatment 1.148889E8 1.7E7 0.87 1.04542826E8 1.27E7 0.69 1.1009 0.993 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D02 compound treatment 9.7042936E7 -846000.0 -0.04 8.8037324E7 -3770000.0 -0.2 -0.1744 -0.8391 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D03 compound treatment 7.1238727E7 -2.67E7 -1.37 7.0701318E7 -2.11E7 -1.14 -1.7697 -0.9958 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D04 compound treatment 8.9273985E7 -8610000.0 -0.44 7.9935838E7 -1.19E7 -0.64 -0.7644 -0.9836 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D05 compound treatment 9.99335E7 2040000.0 0.1 9.9095487E7 7280000.0 0.39 0.3515 0.8657 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D06 compound treatment 1.02452004E8 4560000.0 0.23 9.7696745E7 5890000.0 0.32 0.3895 0.9888 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D07 compound treatment 7.9406893E7 -1.85E7 -0.95 7.7558865E7 -1.43E7 -0.77 -1.2125 -0.9946 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D08 compound treatment 8.8102676E7 -9790000.0 -0.5 8.9407727E7 -2400000.0 -0.13 -0.4462 -0.8614 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D09 compound treatment 8.8722076E7 -9170000.0 -0.47 8.7503162E7 -4310000.0 -0.23 -0.4963 -0.9471 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D10 compound treatment 6.7634371E7 -3.03E7 -1.55 6.707086E7 -2.47E7 -1.33 -2.0385 -0.9971 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D11 mock treatment 9.2709277E7 -5180000.0 -0.27 8.6010877E7 -5800000.0 -0.31 -0.4086 -0.9967 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D12 mock treatment 9.8010317E7 121000.0 0.01 9.0700892E7 -1110000.0 -0.06 -0.0379 -0.6302 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D13 compound treatment 9.4106096E7 -3780000.0 -0.19 8.7926123E7 -3890000.0 -0.21 -0.285 -0.9993 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D14 compound treatment 6.9535291E7 -2.84E7 -1.45 4.7749278E7 -4.41E7 -2.37 -2.7054 -0.9723 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D15 mock treatment 8.4421758E7 -1.35E7 -0.69 8.1785426E7 -1.0E7 -0.54 -0.8698 -0.9926 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D16 mock treatment 8.6773119E7 -1.11E7 -0.57 8.4738874E7 -7070000.0 -0.38 -0.6722 -0.9808 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D17 compound treatment 4.9447088E7 -4.84E7 -2.48 4.9116051E7 -4.27E7 -2.3 -3.3814 -0.9993 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D18 compound treatment 8.712137E7 -1.08E7 -0.55 8.4575598E7 -7240000.0 -0.39 -0.6658 -0.9855 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D19 compound treatment 7.4476108E7 -2.34E7 -1.2 8.1178598E7 -1.06E7 -0.57 -1.2534 -0.9427 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D20 compound treatment 4.7133885E7 -5.08E7 -2.6 4.7329464E7 -4.45E7 -2.4 -3.5332 -0.9992 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D21 compound treatment 5.2073859E7 -4.58E7 -2.35 4.9025277E7 -4.28E7 -2.3 -3.2896 -1.0 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D22 compound treatment 8.5707537E7 -1.22E7 -0.62 8.563688E7 -6170000.0 -0.33 -0.6766 -0.9565 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D23 compound treatment 9.0758075E7 -7130000.0 -0.37 8.7314485E7 -4500000.0 -0.24 -0.4297 -0.98 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 D24 compound treatment 1.07486983E8 9600000.0 0.49 1.04996996E8 1.32E7 0.71 0.8499 0.9839 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E01 mock treatment 1.15015402E8 1.71E7 0.88 1.02430231E8 1.06E7 0.57 1.025 0.9784 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E02 mock treatment 1.1594631E8 1.81E7 0.93 1.01583345E8 9770000.0 0.53 1.0265 0.9642 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E03 compound treatment 1.20391124E8 2.25E7 1.15 1.11033541E8 1.92E7 1.04 1.5474 0.9985 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E04 compound treatment 1.08602637E8 1.07E7 0.55 1.0557592E8 1.38E7 0.74 0.9124 0.9891 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E05 compound treatment 1.04118752E8 6230000.0 0.32 1.02289711E8 1.05E7 0.56 0.6248 0.9636 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E06 compound treatment 1.12767742E8 1.49E7 0.76 1.03161387E8 1.13E7 0.61 0.9714 0.994 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E07 compound treatment 9.249714E7 -5390000.0 -0.28 8.5417761E7 -6390000.0 -0.34 -0.4389 -0.9941 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E08 compound treatment 1.04924405E8 7040000.0 0.36 9.5251453E7 3440000.0 0.19 0.386 0.9521 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E09 mock treatment 1.04763825E8 6870000.0 0.35 9.0273553E7 -1540000.0 -0.08 0.1906 0.5266 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E10 mock treatment 9.8943015E7 1050000.0 0.05 9.1131864E7 -680000.0 -0.04 0.0123 0.1889 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E11 compound treatment 9.602763E7 -1860000.0 -0.1 8.8140923E7 -3670000.0 -0.2 -0.2072 -0.9442 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E12 compound treatment 7.9929908E7 -1.8E7 -0.92 7.1941075E7 -1.99E7 -1.07 -1.4075 -0.9972 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E13 compound treatment 9.5464475E7 -2420000.0 -0.12 8.8468029E7 -3340000.0 -0.18 -0.2152 -0.9836 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E14 compound treatment 8.9328575E7 -8560000.0 -0.44 7.8119051E7 -1.37E7 -0.74 -0.8316 -0.9692 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E15 compound treatment 8.8237615E7 -9650000.0 -0.49 7.9431329E7 -1.24E7 -0.67 -0.8212 -0.9892 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E16 compound treatment 8.5231647E7 -1.27E7 -0.65 8.0369149E7 -1.14E7 -0.62 -0.8944 -0.9997 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E17 mock treatment 8.5483773E7 -1.24E7 -0.64 8.2298186E7 -9510000.0 -0.51 -0.8118 -0.9943 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E18 mock treatment 8.6812531E7 -1.11E7 -0.57 8.6863306E7 -4950000.0 -0.27 -0.5898 -0.9406 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E19 compound treatment 6.5202992E7 -3.27E7 -1.68 7.1818315E7 -2.0E7 -1.08 -1.9459 -0.9772 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E20 compound treatment 9.9042207E7 1150000.0 0.06 9.3943824E7 2130000.0 0.11 0.123 0.9523 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E21 compound treatment 9.1561742E7 -6330000.0 -0.32 9.1099231E7 -712000.0 -0.04 -0.2564 -0.7853 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E22 compound treatment 1.01169901E8 3280000.0 0.17 9.6880244E7 5070000.0 0.27 0.3119 0.9729 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E23 compound treatment 1.01467703E8 3580000.0 0.18 9.4197957E7 2390000.0 0.13 0.2206 0.9849 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 E24 compound treatment 1.09255083E8 1.14E7 0.58 1.01888348E8 1.01E7 0.54 0.7956 0.9994 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F01 mock treatment 1.27866894E8 3.0E7 1.54 1.15298031E8 2.35E7 1.26 1.9808 0.9953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F02 mock treatment 1.17245508E8 1.94E7 0.99 1.0933797E8 1.75E7 0.94 1.3689 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F03 compound treatment 8.0766238E7 -1.71E7 -0.88 7.0828856E7 -2.1E7 -1.13 -1.4195 -0.9922 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F04 compound treatment 9.9141744E7 1250000.0 0.06 9.3403283E7 1590000.0 0.09 0.106 0.9899 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F05 compound treatment 1.0163416E8 3750000.0 0.19 9.0459493E7 -1350000.0 -0.07 0.0842 0.4104 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F06 compound treatment 1.07608336E8 9720000.0 0.5 1.00341117E8 8530000.0 0.46 0.677 0.9992 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F07 compound treatment 1.04855894E8 6970000.0 0.36 1.03117471E8 1.13E7 0.61 0.683 0.9677 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F08 compound treatment 1.01424785E8 3540000.0 0.18 9.5451451E7 3640000.0 0.2 0.2667 0.9992 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F09 mock treatment 1.0647903E8 8590000.0 0.44 9.8106063E7 6290000.0 0.34 0.551 0.9917 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F10 mock treatment 1.01583234E8 3690000.0 0.19 9.1849354E7 37900.0 0.0 0.1353 0.7147 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F11 compound treatment 4.036052E7 -5.75E7 -2.95 4.6634537E7 -4.52E7 -2.43 -3.8052 -0.9954 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F12 compound treatment 9.6885832E7 -1000000.0 -0.05 8.9261167E7 -2550000.0 -0.14 -0.1335 -0.9101 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F13 compound treatment 9.7250569E7 -638000.0 -0.03 8.9826984E7 -1980000.0 -0.11 -0.0987 -0.8831 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F14 compound treatment 9.2930744E7 -4960000.0 -0.25 8.6954185E7 -4860000.0 -0.26 -0.3646 -0.9999 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F15 compound treatment 8.6136975E7 -1.18E7 -0.6 8.3492703E7 -8320000.0 -0.45 -0.7427 -0.9894 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F16 compound treatment 8.3141144E7 -1.47E7 -0.76 8.1433111E7 -1.04E7 -0.56 -0.9297 -0.989 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F17 mock treatment 8.6322532E7 -1.16E7 -0.59 8.4826298E7 -6990000.0 -0.38 -0.6852 -0.9759 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F18 mock treatment 8.7661067E7 -1.02E7 -0.52 8.8042176E7 -3770000.0 -0.2 -0.5142 -0.9147 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F19 compound treatment 9.1887036E7 -6000000.0 -0.31 8.555592E7 -6260000.0 -0.34 -0.4557 -0.999 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F20 compound treatment 8.1869731E7 -1.6E7 -0.82 7.7476652E7 -1.43E7 -0.77 -1.1264 -0.9995 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F21 compound treatment 1.0927203E8 1.14E7 0.58 1.06674035E8 1.49E7 0.8 0.9785 0.9879 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F22 compound treatment 8.6039249E7 -1.18E7 -0.61 8.2377128E7 -9430000.0 -0.51 -0.7887 -0.9961 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F23 compound treatment 9.5041483E7 -2850000.0 -0.15 8.9198091E7 -2610000.0 -0.14 -0.2027 -0.9998 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 F24 compound treatment 7.5853912E7 -2.2E7 -1.13 7.2269261E7 -1.95E7 -1.05 -1.5427 -0.9994 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G01 compound treatment 1.14346802E8 1.65E7 0.84 1.00077502E8 8270000.0 0.45 0.9112 0.9554 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G02 compound treatment 1.29419876E8 3.15E7 1.62 1.20158879E8 2.83E7 1.53 2.2221 0.9996 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G03 mock treatment 1.14082481E8 1.62E7 0.83 1.0806285E8 1.63E7 0.88 1.2057 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G04 mock treatment 1.11128031E8 1.32E7 0.68 1.02340099E8 1.05E7 0.57 0.8807 0.996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G05 compound treatment 1.1741526E8 1.95E7 1.0 1.08588187E8 1.68E7 0.9 1.3465 0.9987 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G06 compound treatment 1.13317406E8 1.54E7 0.79 1.03744661E8 1.19E7 0.64 1.0135 0.9947 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G07 compound treatment 1.02723875E8 4830000.0 0.25 9.4668118E7 2860000.0 0.15 0.284 0.9737 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G08 compound treatment 1.07800591E8 9910000.0 0.51 9.7070644E7 5260000.0 0.28 0.5595 0.9619 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G09 compound treatment 9.04245E7 -7460000.0 -0.38 8.038236E7 -1.14E7 -0.62 -0.7057 -0.9738 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G10 compound treatment 1.239292E8 2.6E7 1.33 1.09430628E8 1.76E7 0.95 1.6146 0.986 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G11 compound treatment 8.0485369E7 -1.74E7 -0.89 7.9116006E7 -1.27E7 -0.68 -1.1141 -0.9914 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G12 compound treatment 9.2590448E7 -5300000.0 -0.27 8.6628998E7 -5180000.0 -0.28 -0.3894 -0.9999 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G13 compound treatment 9.7040143E7 -849000.0 -0.04 9.0005499E7 -1810000.0 -0.1 -0.0995 -0.9342 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G14 compound treatment 9.3379033E7 -4510000.0 -0.23 8.3562598E7 -8250000.0 -0.44 -0.4775 -0.9537 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G15 compound treatment 6.858169E7 -2.93E7 -1.5 7.9202863E7 -1.26E7 -0.68 -1.5422 -0.9356 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G16 compound treatment 8.8350639E7 -9540000.0 -0.49 8.3780666E7 -8030000.0 -0.43 -0.6515 -0.9981 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G17 compound treatment 8.6352978E7 -1.15E7 -0.59 8.6810177E7 -5000000.0 -0.27 -0.6085 -0.9366 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G18 compound treatment 9.1398277E7 -6490000.0 -0.33 8.9014456E7 -2800000.0 -0.15 -0.3417 -0.9358 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G19 mock treatment 8.9215865E7 -8670000.0 -0.44 8.7758592E7 -4050000.0 -0.22 -0.4686 -0.9464 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G20 mock treatment 9.1300788E7 -6590000.0 -0.34 8.8155425E7 -3660000.0 -0.2 -0.378 -0.967 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G21 compound treatment 9.5428867E7 -2460000.0 -0.13 9.1822249E7 10800.0 0.0 -0.0887 -0.7038 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G22 compound treatment 9.7313011E7 -576000.0 -0.03 9.7800895E7 5990000.0 0.32 0.2072 0.6397 3071255 BCB03_000457 NC(=N)NCC#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G23 compound treatment 9.9711599E7 1820000.0 0.09 9.4611402E7 2800000.0 0.15 0.1727 0.9735 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 G24 compound treatment 1.10728986E8 1.28E7 0.66 1.04996138E8 1.32E7 0.71 0.9674 0.9993 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H01 compound treatment 9.4824157E7 -3060000.0 -0.16 9.2781173E7 970000.0 0.05 -0.0741 -0.4479 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H02 compound treatment 1.07269918E8 9380000.0 0.48 1.0682447E8 1.5E7 0.81 0.9116 0.9692 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H03 mock treatment 1.16237226E8 1.83E7 0.94 1.08365608E8 1.66E7 0.89 1.2953 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H04 mock treatment 1.07329043E8 9440000.0 0.48 9.7203377E7 5390000.0 0.29 0.5474 0.9702 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H05 compound treatment 1.06937165E8 9050000.0 0.46 1.01554091E8 9740000.0 0.52 0.6989 0.9981 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H06 compound treatment 1.08463091E8 1.06E7 0.54 1.0152108E8 9710000.0 0.52 0.7529 0.9998 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H07 compound treatment 9.8206149E7 317000.0 0.02 9.6502425E7 4690000.0 0.25 0.1901 0.7511 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H08 compound treatment 1.02791756E8 4900000.0 0.25 9.544996E7 3640000.0 0.2 0.3162 0.9924 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H09 compound treatment 2.6509673E7 -7.14E7 -3.66 2.5705178E7 -6.61E7 -3.56 -5.1041 -0.9999 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H10 compound treatment 1.04036647E8 6150000.0 0.32 9.541094E7 3600000.0 0.19 0.3599 0.9728 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H11 compound treatment 6.6356902E7 -3.15E7 -1.62 7.4269621E7 -1.75E7 -0.94 -1.8107 -0.9673 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H12 compound treatment 9.7199566E7 -689000.0 -0.04 9.1801241E7 -10200.0 0.0 -0.0254 -0.718 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H13 compound treatment 9.7389307E7 -500000.0 -0.03 9.2175082E7 364000.0 0.02 -0.0043 -0.1322 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H14 compound treatment 9.7497418E7 -392000.0 -0.02 8.9681705E7 -2130000.0 -0.11 -0.0953 -0.8184 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H15 compound treatment 9.3604365E7 -4280000.0 -0.22 8.872497E7 -3090000.0 -0.17 -0.2728 -0.9906 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H16 compound treatment 8.8191506E7 -9700000.0 -0.5 8.1691182E7 -1.01E7 -0.54 -0.7368 -0.9989 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H17 compound treatment 8.5218822E7 -1.27E7 -0.65 8.8382554E7 -3430000.0 -0.18 -0.5897 -0.8735 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H18 compound treatment 9.0367071E7 -7520000.0 -0.39 9.0550651E7 -1260000.0 -0.07 -0.3206 -0.819 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H19 mock treatment 9.6526714E7 -1360000.0 -0.07 9.1729618E7 -81800.0 0.0 -0.0525 -0.7502 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H20 mock treatment 9.187404E7 -6010000.0 -0.31 8.8910565E7 -2900000.0 -0.16 -0.3284 -0.9504 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H21 compound treatment 4.7898516E7 -5.0E7 -2.56 4.9671422E7 -4.21E7 -2.27 -3.4163 -0.9982 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H22 compound treatment 7.9753729E7 -1.81E7 -0.93 7.9789118E7 -1.2E7 -0.65 -1.115 -0.9844 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H23 compound treatment 1.03096511E8 5210000.0 0.27 9.8048896E7 6240000.0 0.34 0.4262 0.9935 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 H24 compound treatment 1.10138679E8 1.22E7 0.63 1.06712398E8 1.49E7 0.8 1.0113 0.9926 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I01 compound treatment 1.20760203E8 2.29E7 1.17 1.05010019E8 1.32E7 0.71 1.3315 0.9713 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I02 compound treatment 1.12904718E8 1.5E7 0.77 1.06882542E8 1.51E7 0.81 1.1181 0.9996 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I03 compound treatment 1.14264183E8 1.64E7 0.84 1.06101511E8 1.43E7 0.77 1.1376 0.9991 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I04 compound treatment 1.11800226E8 1.39E7 0.71 1.02864454E8 1.11E7 0.6 0.925 0.996 1035256 BCB03_000483 C#CCNCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I05 mock treatment 1.05925952E8 8040000.0 0.41 9.2857794E7 1050000.0 0.06 0.3311 0.7964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I06 mock treatment 1.07784537E8 9900000.0 0.51 9.9191221E7 7380000.0 0.4 0.6396 0.9927 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I07 compound treatment 1.10269944E8 1.24E7 0.63 1.00288234E8 8480000.0 0.46 0.7715 0.9869 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I08 compound treatment 1.0226256E8 4370000.0 0.22 8.8989426E7 -2820000.0 -0.15 0.051 0.1885 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I09 compound treatment 8.4045622E7 -1.38E7 -0.71 7.479523E7 -1.7E7 -0.92 -1.1496 -0.992 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I10 compound treatment 9.6189911E7 -1700000.0 -0.09 9.1384216E7 -427000.0 -0.02 -0.0778 -0.8643 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I11 compound treatment 9.7704871E7 -184000.0 -0.01 9.3838993E7 2030000.0 0.11 0.0705 0.6436 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I12 compound treatment 1.01778499E8 3890000.0 0.2 9.0906471E7 -905000.0 -0.05 0.1065 0.519 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I13 compound treatment 8.4599787E7 -1.33E7 -0.68 7.8673416E7 -1.31E7 -0.71 -0.9819 -0.9998 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I14 compound treatment 9.7710997E7 -178000.0 -0.01 8.8764071E7 -3050000.0 -0.16 -0.1225 -0.7453 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I15 compound treatment 7.8458678E7 -1.94E7 -1.0 8.3272562E7 -8540000.0 -0.46 -1.0293 -0.9384 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I16 compound treatment 7.8975315E7 -1.89E7 -0.97 7.2607689E7 -1.92E7 -1.03 -1.4167 -0.9995 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I17 compound treatment 8.7657008E7 -1.02E7 -0.52 8.6631774E7 -5180000.0 -0.28 -0.568 -0.9563 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I18 compound treatment 9.4506747E7 -3380000.0 -0.17 8.9148158E7 -2660000.0 -0.14 -0.224 -0.9956 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I19 compound treatment 9.7177893E7 -711000.0 -0.04 8.9897141E7 -1910000.0 -0.1 -0.0987 -0.9024 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I20 compound treatment 9.6755261E7 -1130000.0 -0.06 9.3615104E7 1800000.0 0.1 0.0276 0.2438 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I21 mock treatment 9.1755715E7 -6130000.0 -0.31 8.9739688E7 -2070000.0 -0.11 -0.3012 -0.9029 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I22 mock treatment 9.3318575E7 -4570000.0 -0.23 9.1831275E7 19800.0 0.0 -0.1649 -0.7039 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I23 compound treatment 9.6396462E7 -1490000.0 -0.08 9.0462179E7 -1350000.0 -0.07 -0.1055 -0.9997 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 I24 compound treatment 1.05272021E8 7380000.0 0.38 1.04891295E8 1.31E7 0.7 0.7656 0.9576 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J01 compound treatment 1.13254251E8 1.54E7 0.79 1.03776856E8 1.2E7 0.64 1.0125 0.995 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J02 compound treatment 1.1181912E8 1.39E7 0.71 1.0868749E8 1.69E7 0.91 1.1475 0.9929 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J03 compound treatment 1.05044061E8 7160000.0 0.37 1.00849214E8 9040000.0 0.49 0.6035 0.9903 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J04 compound treatment 1.01346871E8 3460000.0 0.18 9.6809558E7 5000000.0 0.27 0.3156 0.9794 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J05 mock treatment 1.08176636E8 1.03E7 0.53 1.02357504E8 1.05E7 0.57 0.7744 0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J06 mock treatment 1.07616776E8 9730000.0 0.5 1.01587236E8 9780000.0 0.53 0.7248 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J07 compound treatment 9.9451558E7 1560000.0 0.08 7.5606111E7 -1.62E7 -0.87 -0.5604 -0.6395 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J08 compound treatment 9.7481717E7 -407000.0 -0.02 8.7793368E7 -4020000.0 -0.22 -0.1678 -0.7717 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J09 compound treatment 1.06843505E8 8950000.0 0.46 9.8027636E7 6220000.0 0.33 0.5612 0.988 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J10 compound treatment 5.7835083E7 -4.01E7 -2.05 5.9335908E7 -3.25E7 -1.75 -2.6882 -0.9968 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J11 compound treatment 1.14687987E8 1.68E7 0.86 1.06026741E8 1.42E7 0.77 1.1501 0.9983 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J12 compound treatment 9.1523603E7 -6370000.0 -0.33 8.5908024E7 -5900000.0 -0.32 -0.4555 -0.9999 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J13 compound treatment 8.3559311E7 -1.43E7 -0.73 8.3104749E7 -8710000.0 -0.47 -0.8509 -0.9765 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J14 compound treatment 6.3786232E7 -3.41E7 -1.75 6.4722272E7 -2.71E7 -1.46 -2.2674 -0.996 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J15 compound treatment 4.3712136E7 -5.42E7 -2.78 3.9079381E7 -5.27E7 -2.84 -3.9714 -0.9999 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J16 compound treatment 7.9041949E7 -1.88E7 -0.97 7.3879723E7 -1.79E7 -0.97 -1.3658 -1.0 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J17 compound treatment 6.9819701E7 -2.81E7 -1.44 6.9958371E7 -2.19E7 -1.18 -1.8494 -0.995 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J18 compound treatment 9.2441786E7 -5450000.0 -0.28 8.7350507E7 -4460000.0 -0.24 -0.3673 -0.9972 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J19 compound treatment 5.782752E7 -4.01E7 -2.05 5.8182469E7 -3.36E7 -1.81 -2.7324 -0.998 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J20 compound treatment 7.7766513E7 -2.01E7 -1.03 7.3577659E7 -1.82E7 -0.98 -1.4236 -0.9997 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J21 mock treatment 9.4819116E7 -3070000.0 -0.16 9.148032E7 -331000.0 -0.02 -0.1239 -0.7822 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J22 mock treatment 9.406506E7 -3820000.0 -0.2 9.1217246E7 -594000.0 -0.03 -0.1612 -0.8118 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J23 compound treatment 1.06025667E8 8140000.0 0.42 9.7209666E7 5400000.0 0.29 0.5004 0.9844 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 J24 compound treatment 1.08234364E8 1.03E7 0.53 1.09343187E8 1.75E7 0.94 1.0425 0.9628 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K01 compound treatment 6.7560257E7 -3.03E7 -1.55 5.3823931E7 -3.8E7 -2.05 -2.5456 -0.9908 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K02 compound treatment 1.0704085E8 9150000.0 0.47 1.08237621E8 1.64E7 0.88 0.9572 0.956 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K03 compound treatment 1.03684557E8 5800000.0 0.3 9.9492861E7 7680000.0 0.41 0.5025 0.9868 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K04 compound treatment 1.12055712E8 1.42E7 0.73 1.03763181E8 1.2E7 0.64 0.9685 0.9982 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K05 compound treatment 1.02084464E8 4200000.0 0.22 9.9465183E7 7650000.0 0.41 0.4435 0.954 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K06 compound treatment 1.01149861E8 3260000.0 0.17 9.4777554E7 2970000.0 0.16 0.2311 0.9997 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K07 mock treatment 1.01336204E8 3450000.0 0.18 9.741878E7 5610000.0 0.3 0.3385 0.9674 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K08 mock treatment 9.8384499E7 496000.0 0.03 9.049925E7 -1310000.0 -0.07 -0.032 -0.4263 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K09 compound treatment 9.2228202E7 -5660000.0 -0.29 8.968796E7 -2120000.0 -0.11 -0.286 -0.9171 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K10 compound treatment 9.6516738E7 -1370000.0 -0.07 8.8166923E7 -3640000.0 -0.2 -0.1885 -0.9042 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K11 compound treatment 1.01640462E8 3750000.0 0.19 9.1996518E7 185000.0 0.01 0.143 0.7428 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K12 compound treatment 9.4272407E7 -3620000.0 -0.19 8.6727608E7 -5080000.0 -0.27 -0.3247 -0.982 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K13 compound treatment 6.9445938E7 -2.84E7 -1.46 6.3781043E7 -2.8E7 -1.51 -2.0982 -0.9998 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K14 compound treatment 9.2184507E7 -5700000.0 -0.29 8.534922E7 -6460000.0 -0.35 -0.4528 -0.9962 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K15 mock treatment 9.3055005E7 -4830000.0 -0.25 8.8610667E7 -3200000.0 -0.17 -0.2971 -0.9843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K16 mock treatment 8.9506182E7 -8380000.0 -0.43 8.5394683E7 -6420000.0 -0.35 -0.5481 -0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K17 compound treatment 9.9582388E7 1690000.0 0.09 9.4582224E7 2770000.0 0.15 0.1669 0.9668 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K18 compound treatment 9.2412067E7 -5480000.0 -0.28 8.8712031E7 -3100000.0 -0.17 -0.3165 -0.9692 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K19 compound treatment 9.5610317E7 -2280000.0 -0.12 9.0206109E7 -1610000.0 -0.09 -0.1437 -0.989 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K20 compound treatment 9.3848764E7 -4040000.0 -0.21 8.9364396E7 -2450000.0 -0.13 -0.2396 -0.9762 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K21 compound treatment 1.06723952E8 8840000.0 0.45 1.00019973E8 8210000.0 0.44 0.6328 0.9999 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K22 compound treatment 9.2400706E7 -5490000.0 -0.28 9.2641631E7 830000.0 0.04 -0.1673 -0.5874 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K23 mock treatment 9.6175499E7 -1710000.0 -0.09 9.6944447E7 5130000.0 0.28 0.1334 0.4598 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 K24 mock treatment 1.05448588E8 7560000.0 0.39 1.09933228E8 1.81E7 0.98 0.964 0.9181 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L01 compound treatment 1.11852126E8 1.4E7 0.72 1.10810744E8 1.9E7 1.02 1.2295 0.9847 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L02 compound treatment 1.07781414E8 9890000.0 0.51 1.02525884E8 1.07E7 0.58 0.7665 0.9979 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L03 compound treatment 9.379913E7 -4090000.0 -0.21 8.6658848E7 -5150000.0 -0.28 -0.3444 -0.9904 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L04 compound treatment 7.4888343E7 -2.3E7 -1.18 6.9766412E7 -2.2E7 -1.19 -1.673 -1.0 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L05 compound treatment 1.05766369E8 7880000.0 0.4 1.03240902E8 1.14E7 0.62 0.7207 0.9791 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L06 compound treatment 9.7192247E7 -697000.0 -0.04 9.5586702E7 3780000.0 0.2 0.1185 0.5741 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L07 mock treatment 1.00862328E8 2970000.0 0.15 9.3053329E7 1240000.0 0.07 0.155 0.9317 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L08 mock treatment 9.617514E7 -1710000.0 -0.09 8.9010851E7 -2800000.0 -0.15 -0.1688 -0.9669 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L09 compound treatment 9.6966801E7 -922000.0 -0.05 8.8502589E7 -3310000.0 -0.18 -0.1594 -0.8648 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L10 compound treatment 1.02336807E8 4450000.0 0.23 9.3333027E7 1520000.0 0.08 0.2191 0.9046 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L11 compound treatment 8.7619611E7 -1.03E7 -0.53 8.2428326E7 -9380000.0 -0.51 -0.7295 -0.9998 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L12 compound treatment 8.5102111E7 -1.28E7 -0.66 7.3862771E7 -1.79E7 -0.97 -1.1469 -0.9821 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L13 compound treatment 8.5277152E7 -1.26E7 -0.65 8.6575989E7 -5240000.0 -0.28 -0.6564 -0.9308 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L14 compound treatment 9.646319E7 -1430000.0 -0.07 8.267175E7 -9140000.0 -0.49 -0.3997 -0.8033 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L15 mock treatment 9.3961605E7 -3930000.0 -0.2 8.5529692E7 -6280000.0 -0.34 -0.3815 -0.9692 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L16 mock treatment 9.0914071E7 -6970000.0 -0.36 8.9849755E7 -1960000.0 -0.11 -0.3275 -0.8785 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L17 compound treatment 5.2739475E7 -4.51E7 -2.31 4.7879648E7 -4.39E7 -2.37 -3.3091 -0.9999 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L18 compound treatment 9.8048304E7 159000.0 0.01 8.6114806E7 -5700000.0 -0.31 -0.2111 -0.688 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L19 compound treatment 9.3016998E7 -4870000.0 -0.25 8.8701188E7 -3110000.0 -0.17 -0.295 -0.9811 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L20 compound treatment 8.9691339E7 -8200000.0 -0.42 8.3778906E7 -8030000.0 -0.43 -0.603 -0.9999 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L21 compound treatment 7.3900042E7 -2.4E7 -1.23 6.9184882E7 -2.26E7 -1.22 -1.731 -1.0 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L22 compound treatment 9.4173926E7 -3720000.0 -0.19 8.9435506E7 -2380000.0 -0.13 -0.2251 -0.9813 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L23 mock treatment 1.01001038E8 3110000.0 0.16 9.411485E7 2300000.0 0.12 0.2005 0.9923 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 L24 mock treatment 1.09017361E8 1.11E7 0.57 1.02718105E8 1.09E7 0.59 0.8186 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M01 compound treatment 1.39306851E8 4.14E7 2.12 1.3055273E8 3.87E7 2.09 2.9762 1.0 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M02 compound treatment 1.12928878E8 1.5E7 0.77 1.09496783E8 1.77E7 0.95 1.2185 0.9945 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M03 compound treatment 1.12889234E8 1.5E7 0.77 9.8395921E7 6580000.0 0.35 0.7944 0.9382 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M04 compound treatment 1.1074208E8 1.29E7 0.66 1.05177559E8 1.34E7 0.72 0.9748 0.999 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M05 compound treatment 1.09224884E8 1.13E7 0.58 9.3913667E7 2100000.0 0.11 0.4909 0.8293 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M06 compound treatment 1.05300728E8 7410000.0 0.38 9.9498032E7 7690000.0 0.41 0.5613 0.9991 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M07 compound treatment 9.9514388E7 1630000.0 0.08 8.5874674E7 -5940000.0 -0.32 -0.1672 -0.506 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M08 compound treatment 1.06481287E8 8590000.0 0.44 9.7056706E7 5250000.0 0.28 0.5111 0.977 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M09 mock treatment 9.7091114E7 -798000.0 -0.04 8.9114298E7 -2700000.0 -0.15 -0.1316 -0.8723 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M10 mock treatment 9.5555155E7 -2330000.0 -0.12 8.7347365E7 -4460000.0 -0.24 -0.2546 -0.9481 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M11 compound treatment 1.09802812E8 1.19E7 0.61 9.470281E7 2890000.0 0.16 0.5419 0.8599 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M12 compound treatment 1.04029206E8 6140000.0 0.31 9.315872E7 1350000.0 0.07 0.2738 0.8479 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M13 mock treatment 9.7652148E7 -237000.0 -0.01 8.6647544E7 -5160000.0 -0.28 -0.2052 -0.7373 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M14 mock treatment 9.5161212E7 -2730000.0 -0.14 8.8416855E7 -3390000.0 -0.18 -0.2281 -0.9912 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M15 compound treatment 8.6377808E7 -1.15E7 -0.59 6.8921231E7 -2.29E7 -1.23 -1.2888 -0.9431 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M16 compound treatment 9.2161026E7 -5730000.0 -0.29 8.55557E7 -6260000.0 -0.34 -0.4458 -0.9976 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M17 compound treatment 9.940842E7 1520000.0 0.08 9.4207051E7 2400000.0 0.13 0.1463 0.9708 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M18 compound treatment 9.212887E7 -5760000.0 -0.3 8.7365047E7 -4450000.0 -0.24 -0.3781 -0.9946 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M19 compound treatment 1.06727699E8 8840000.0 0.45 9.888209E7 7070000.0 0.38 0.5896 0.9963 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M20 compound treatment 9.4096072E7 -3790000.0 -0.19 8.7352409E7 -4460000.0 -0.24 -0.3073 -0.9945 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M21 compound treatment 1.04329219E8 6440000.0 0.33 9.8810097E7 7000000.0 0.38 0.4999 0.9978 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M22 compound treatment 1.00313865E8 2420000.0 0.12 9.7674011E7 5860000.0 0.32 0.3111 0.917 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M23 compound treatment 9.7943596E7 54700.0 0.0 1.00340981E8 8530000.0 0.46 0.3268 0.7114 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 M24 compound treatment 1.08728686E8 1.08E7 0.56 1.06110226E8 1.43E7 0.77 0.9373 0.9872 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N01 compound treatment 1.07532968E8 9640000.0 0.49 1.03116748E8 1.13E7 0.61 0.78 0.9947 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N02 compound treatment 1.19498199E8 2.16E7 1.11 1.13821173E8 2.2E7 1.19 1.6212 0.9994 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N03 compound treatment 8.4223063E7 -1.37E7 -0.7 8.2591883E7 -9220000.0 -0.5 -0.8463 -0.9858 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N04 compound treatment 1.00921477E8 3030000.0 0.16 1.01101298E8 9290000.0 0.5 0.4636 0.8851 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N05 compound treatment 9.2934774E7 -4950000.0 -0.25 7.8648593E7 -1.32E7 -0.71 -0.6808 -0.9041 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N06 compound treatment 3.3990046E7 -6.39E7 -3.27 3.1991187E7 -5.98E7 -3.22 -4.5936 -1.0 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N07 compound treatment 6.2667813E7 -3.52E7 -1.81 5.4604035E7 -3.72E7 -2.0 -2.6932 -0.9986 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N08 compound treatment 8.2115787E7 -1.58E7 -0.81 7.0107217E7 -2.17E7 -1.17 -1.3981 -0.9838 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N09 mock treatment 9.5943315E7 -1950000.0 -0.1 8.7377278E7 -4430000.0 -0.24 -0.2394 -0.925 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N10 mock treatment 9.2063675E7 -5830000.0 -0.3 8.6674216E7 -5140000.0 -0.28 -0.4067 -0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N11 compound treatment 5.5558031E7 -4.23E7 -2.17 4.9231266E7 -4.26E7 -2.29 -3.1555 -0.9996 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N12 compound treatment 3.8196916E7 -5.97E7 -3.06 3.6632091E7 -5.52E7 -2.97 -4.2644 -0.9999 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N13 mock treatment 9.86401E7 751000.0 0.04 8.7402831E7 -4410000.0 -0.24 -0.1407 -0.5848 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N14 mock treatment 9.193367E7 -5960000.0 -0.31 8.734344E7 -4470000.0 -0.24 -0.386 -0.9931 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N15 compound treatment 6.5585469E7 -3.23E7 -1.66 4.7886435E7 -4.39E7 -2.37 -2.8433 -0.9848 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N16 compound treatment 4.5246297E7 -5.26E7 -2.7 3.5678222E7 -5.61E7 -3.02 -4.0453 -0.9984 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N17 compound treatment 4.3411967E7 -5.45E7 -2.79 3.9054456E7 -5.28E7 -2.84 -3.9832 -1.0 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N18 compound treatment 3.5184851E7 -6.27E7 -3.21 3.3514352E7 -5.83E7 -3.14 -4.4923 -0.9999 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N19 compound treatment 5.0066637E7 -4.78E7 -2.45 4.640583E7 -4.54E7 -2.45 -3.4621 -1.0 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N20 compound treatment 4.4111922E7 -5.38E7 -2.76 4.4715081E7 -4.71E7 -2.54 -3.7423 -0.9991 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N21 compound treatment 6.6938597E7 -3.1E7 -1.59 5.8534458E7 -3.33E7 -1.79 -2.3888 -0.9982 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N22 compound treatment 7.5893905E7 -2.2E7 -1.13 7.4298335E7 -1.75E7 -0.94 -1.464 -0.9961 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N23 compound treatment 9.3587346E7 -4300000.0 -0.22 8.5307546E7 -6500000.0 -0.35 -0.4036 -0.9751 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 N24 compound treatment 1.00290975E8 2400000.0 0.12 8.4919065E7 -6890000.0 -0.37 -0.1754 -0.4485 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O01 compound treatment 1.0864758E8 1.08E7 0.55 1.12929577E8 2.11E7 1.14 1.194 0.9448 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O02 compound treatment 1.11583331E8 1.37E7 0.7 1.04973065E8 1.32E7 0.71 0.9975 1.0 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O03 compound treatment 9.9313183E7 1420000.0 0.07 8.7857221E7 -3950000.0 -0.21 -0.099 -0.4396 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O04 compound treatment 1.11796581E8 1.39E7 0.71 1.03274998E8 1.15E7 0.62 0.9405 0.9974 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O05 compound treatment 1.17052167E8 1.92E7 0.98 1.13149063E8 2.13E7 1.15 1.507 0.9969 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O06 compound treatment 1.05745315E8 7860000.0 0.4 9.0700421E7 -1110000.0 -0.06 0.2424 0.5955 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O07 compound treatment 1.06452408E8 8560000.0 0.44 9.2278082E7 467000.0 0.03 0.3281 0.7464 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O08 compound treatment 9.1665879E7 -6220000.0 -0.32 8.6120805E7 -5690000.0 -0.31 -0.4422 -0.9998 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O09 compound treatment 1.0912366E8 1.12E7 0.58 9.7752659E7 5940000.0 0.32 0.6334 0.9615 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O10 compound treatment 9.4390162E7 -3500000.0 -0.18 9.4758019E7 2950000.0 0.16 -0.0146 -0.061 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O11 mock treatment 9.5509339E7 -2380000.0 -0.12 9.2518125E7 707000.0 0.04 -0.0593 -0.4644 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O12 mock treatment 9.8826286E7 937000.0 0.05 1.00225696E8 8410000.0 0.45 0.3544 0.7777 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O13 compound treatment 1.25507694E8 2.76E7 1.42 1.09095702E8 1.73E7 0.93 1.6591 0.9793 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O14 compound treatment 1.07980813E8 1.01E7 0.52 9.6576788E7 4770000.0 0.26 0.5472 0.9477 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O15 compound treatment 9.9264867E7 1380000.0 0.07 9.0769006E7 -1040000.0 -0.06 0.0102 0.1128 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O16 compound treatment 9.63025E7 -1590000.0 -0.08 9.2623396E7 812000.0 0.04 -0.0266 -0.2879 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O17 compound treatment 9.5666185E7 -2220000.0 -0.11 8.9471644E7 -2340000.0 -0.13 -0.1697 -0.9987 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O18 compound treatment 1.02433E8 4540000.0 0.23 9.0731607E7 -1080000.0 -0.06 0.1236 0.5147 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O19 compound treatment 9.0333259E7 -7560000.0 -0.39 7.1060176E7 -2.08E7 -1.12 -1.064 -0.8997 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O20 compound treatment 9.6295779E7 -1590000.0 -0.08 8.5201314E7 -6610000.0 -0.36 -0.3094 -0.8473 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O21 compound treatment 1.07079828E8 9190000.0 0.47 1.0283756E8 1.1E7 0.59 0.7529 0.9934 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O22 compound treatment 9.6338912E7 -1550000.0 -0.08 8.9260487E7 -2550000.0 -0.14 -0.1533 -0.9661 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O23 compound treatment 1.0898614E8 1.11E7 0.57 9.5913097E7 4100000.0 0.22 0.5584 0.9151 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 O24 compound treatment 1.13760308E8 1.59E7 0.81 1.059721E8 1.42E7 0.76 1.1144 0.9995 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P01 compound treatment 9.3738308E7 -4150000.0 -0.21 1.00594859E8 8780000.0 0.47 0.184 0.3548 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P02 compound treatment 1.08734994E8 1.08E7 0.56 1.06354726E8 1.45E7 0.78 0.9469 0.9859 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P03 compound treatment 9.3994724E7 -3890000.0 -0.2 9.0086357E7 -1730000.0 -0.09 -0.2068 -0.9395 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P04 compound treatment 1.03535775E8 5650000.0 0.29 9.481785E7 3010000.0 0.16 0.3191 0.9623 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P05 compound treatment 9.3745342E7 -4140000.0 -0.21 9.0270555E7 -1540000.0 -0.08 -0.2088 -0.916 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P06 compound treatment 9.3700145E7 -4190000.0 -0.21 9.5133113E7 3320000.0 0.18 -0.0253 -0.0906 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P07 compound treatment 7.7048428E7 -2.08E7 -1.07 5.5241464E7 -3.66E7 -1.97 -2.1478 -0.9587 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P08 compound treatment 9.046503E7 -7420000.0 -0.38 8.198236E7 -9830000.0 -0.53 -0.6433 -0.9869 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P09 compound treatment 6.6433874E7 -3.15E7 -1.61 6.5868708E7 -2.59E7 -1.4 -2.1278 -0.9975 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P10 compound treatment 9.7219878E7 -669000.0 -0.03 9.6467109E7 4660000.0 0.25 0.153 0.6048 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P11 mock treatment 1.0155847E8 3670000.0 0.19 9.615014E7 4340000.0 0.23 0.2982 0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P12 mock treatment 1.01749248E8 3860000.0 0.2 1.0857897E8 1.68E7 0.9 0.7784 0.8421 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P13 compound treatment 6.1995753E7 -3.59E7 -1.84 5.8732615E7 -3.31E7 -1.78 -2.5604 -0.9999 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P14 compound treatment 7.2200954E7 -2.57E7 -1.32 6.9589857E7 -2.22E7 -1.2 -1.7771 -0.9989 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P15 compound treatment 8.7990109E7 -9900000.0 -0.51 8.0579062E7 -1.12E7 -0.6 -0.7865 -0.9962 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P16 compound treatment 9.4029138E7 -3860000.0 -0.2 8.9215797E7 -2600000.0 -0.14 -0.2387 -0.9855 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P17 compound treatment 4.5776537E7 -5.21E7 -2.67 4.454154E7 -4.73E7 -2.55 -3.6886 -0.9997 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P18 compound treatment 9.8944217E7 1060000.0 0.05 1.01733094E8 9920000.0 0.53 0.416 0.7747 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P19 compound treatment 8.3936486E7 -1.4E7 -0.72 7.7661247E7 -1.42E7 -0.76 -1.0445 -0.9995 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P20 compound treatment 1.08401229E8 1.05E7 0.54 9.6082057E7 4270000.0 0.23 0.5436 0.9279 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P21 compound treatment 7.9237063E7 -1.87E7 -0.96 8.2398247E7 -9410000.0 -0.51 -1.0344 -0.956 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P22 compound treatment 1.04452122E8 6560000.0 0.34 9.3706504E7 1900000.0 0.1 0.31 0.8819 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P23 compound treatment 8.3554926E7 -1.43E7 -0.73 8.1862195E7 -9950000.0 -0.54 -0.8983 -0.988 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2282 P24 compound treatment 1.37056901E8 3.92E7 2.01 1.15446812E8 2.36E7 1.27 2.3195 0.9758 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A01 compound treatment 1.12086873E8 2.22E7 1.14 1.13396419E8 1.7E7 0.91 1.4494 0.9942 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A02 compound treatment 9.2835795E7 2910000.0 0.15 9.2673557E7 -3750000.0 -0.2 -0.0373 -0.1486 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A03 compound treatment 9.7934911E7 8010000.0 0.41 9.5280234E7 -1150000.0 -0.06 0.2467 0.5942 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A04 compound treatment 1.05716243E8 1.58E7 0.81 1.08768513E8 1.23E7 0.66 1.0423 0.9952 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A05 compound treatment 9.4851816E7 4930000.0 0.25 9.6484429E7 59100.0 0.0 0.1808 0.716 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A06 compound treatment 9.2550417E7 2630000.0 0.13 8.841676E7 -8010000.0 -0.43 -0.2098 -0.4643 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A07 compound treatment 8.8589574E7 -1330000.0 -0.07 9.2286433E7 -4140000.0 -0.22 -0.206 -0.8834 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A08 compound treatment 9.2203722E7 2280000.0 0.12 9.0590848E7 -5830000.0 -0.31 -0.1395 -0.4163 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A09 compound treatment 8.1131454E7 -8790000.0 -0.45 7.8986681E7 -1.74E7 -0.94 -0.9827 -0.9434 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A10 compound treatment 6.9901598E7 -2.0E7 -1.03 6.4549302E7 -3.19E7 -1.72 -1.9394 -0.9698 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A11 compound treatment 8.0898506E7 -9030000.0 -0.46 7.8541499E7 -1.79E7 -0.96 -1.0081 -0.9435 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A12 compound treatment 7.8865606E7 -1.11E7 -0.57 7.6641644E7 -1.98E7 -1.07 -1.1541 -0.9564 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A13 mock treatment 9.0853804E7 930000.0 0.05 9.0541511E7 -5880000.0 -0.32 -0.1904 -0.5941 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A14 mock treatment 7.9244191E7 -1.07E7 -0.55 8.0789996E7 -1.56E7 -0.84 -0.9824 -0.9782 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A15 compound treatment 6.2837119E7 -2.71E7 -1.39 6.0830747E7 -3.56E7 -1.92 -2.337 -0.9875 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A16 compound treatment 7.6713707E7 -1.32E7 -0.68 7.2526263E7 -2.39E7 -1.29 -1.3888 -0.955 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A17 compound treatment 7.6626454E7 -1.33E7 -0.68 8.2019847E7 -1.44E7 -0.78 -1.0305 -0.9979 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A18 compound treatment 9.3472165E7 3550000.0 0.18 1.01279836E8 4850000.0 0.26 0.3134 0.9843 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A19 compound treatment 8.3911319E7 -6010000.0 -0.31 8.9049817E7 -7380000.0 -0.4 -0.4988 -0.9921 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A20 compound treatment 7.5569563E7 -1.44E7 -0.74 7.8583898E7 -1.78E7 -0.96 -1.1996 -0.9913 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A21 compound treatment 7.3038673E7 -1.69E7 -0.87 7.7341304E7 -1.91E7 -1.03 -1.3386 -0.9963 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A22 compound treatment 8.9938848E7 14800.0 0.0 1.00235229E8 3810000.0 0.21 0.1456 0.7097 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A23 compound treatment 9.4256579E7 4330000.0 0.22 9.7529784E7 1100000.0 0.06 0.1991 0.866 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 A24 compound treatment 1.14611361E8 2.47E7 1.27 1.18479437E8 2.21E7 1.19 1.7345 0.9995 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B01 compound treatment 1.10283768E8 2.04E7 1.04 1.12535321E8 1.61E7 0.87 1.3513 0.9958 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B02 compound treatment 9.6373265E7 6450000.0 0.33 9.7068082E7 643000.0 0.03 0.2582 0.7769 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B03 compound treatment 7.921415E7 -1.07E7 -0.55 7.7816687E7 -1.86E7 -1.0 -1.0967 -0.9599 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B04 compound treatment 8.5710948E7 -4210000.0 -0.22 8.3750163E7 -1.27E7 -0.68 -0.6353 -0.8875 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B05 compound treatment 7.5964673E7 -1.4E7 -0.72 7.8983524E7 -1.74E7 -0.94 -1.1701 -0.991 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B06 compound treatment 7.1295158E7 -1.86E7 -0.95 6.6479256E7 -2.99E7 -1.61 -1.8154 -0.9687 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B07 compound treatment 7.8912926E7 -1.1E7 -0.56 8.7546488E7 -8880000.0 -0.48 -0.7371 -0.9966 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B08 compound treatment 8.3089282E7 -6830000.0 -0.35 7.8655288E7 -1.78E7 -0.96 -0.9244 -0.9071 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B09 compound treatment 7.951027E7 -1.04E7 -0.53 8.0308732E7 -1.61E7 -0.87 -0.9911 -0.9727 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B10 compound treatment 3.0036941E7 -5.99E7 -3.07 3.1035884E7 -6.54E7 -3.52 -4.6603 -0.9977 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B11 compound treatment 7.2458433E7 -1.75E7 -0.9 6.9626409E7 -2.68E7 -1.44 -1.6534 -0.9736 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B12 compound treatment 2.9198945E7 -6.07E7 -3.11 3.0789879E7 -6.56E7 -3.53 -4.7 -0.998 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B13 mock treatment 7.2192178E7 -1.77E7 -0.91 7.2006627E7 -2.44E7 -1.31 -1.5724 -0.9837 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B14 mock treatment 6.8488664E7 -2.14E7 -1.1 7.3045289E7 -2.34E7 -1.26 -1.6671 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B15 compound treatment 7.5050455E7 -1.49E7 -0.76 7.7571625E7 -1.89E7 -1.02 -1.257 -0.99 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B16 compound treatment 2.7955461E7 -6.2E7 -3.18 2.9143187E7 -6.73E7 -3.62 -4.8078 -0.9978 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B17 compound treatment 7.8500091E7 -1.14E7 -0.59 7.802158E7 -1.84E7 -0.99 -1.1148 -0.9685 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B18 compound treatment 2.8436038E7 -6.15E7 -3.15 2.973E7 -6.67E7 -3.59 -4.768 -0.9979 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B19 compound treatment 7.7139675E7 -1.28E7 -0.66 8.2098262E7 -1.43E7 -0.77 -1.0089 -0.9967 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B20 compound treatment 2.6255839E7 -6.37E7 -3.26 2.7565544E7 -6.89E7 -3.71 -4.9295 -0.998 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B21 compound treatment 8.2614753E7 -7310000.0 -0.37 9.3296364E7 -3130000.0 -0.17 -0.384 -0.9349 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B22 compound treatment 3.0496128E7 -5.94E7 -3.05 3.2788805E7 -6.36E7 -3.43 -4.5769 -0.9983 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B23 compound treatment 9.1247921E7 1320000.0 0.07 1.00510463E8 4090000.0 0.22 0.2035 0.8841 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 B24 compound treatment 3.4586333E7 -5.53E7 -2.84 3.6942464E7 -5.95E7 -3.2 -4.2705 -0.9982 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C01 compound treatment 1.05037029E8 1.51E7 0.77 1.03771078E8 7350000.0 0.4 0.8274 0.9513 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C02 compound treatment 9.3874193E7 3950000.0 0.2 9.123667E7 -5190000.0 -0.28 -0.0544 -0.1577 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C03 compound treatment 8.8491387E7 -1430000.0 -0.07 8.6919594E7 -9510000.0 -0.51 -0.4139 -0.8003 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C04 compound treatment 9.835911E7 8440000.0 0.43 9.4857616E7 -1570000.0 -0.08 0.246 0.5585 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C05 compound treatment 8.2042001E7 -7880000.0 -0.4 7.7682765E7 -1.87E7 -1.01 -0.9993 -0.9192 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C06 compound treatment 9.2489543E7 2570000.0 0.13 9.1680254E7 -4750000.0 -0.26 -0.0877 -0.3052 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C07 compound treatment 7.8995383E7 -1.09E7 -0.56 8.3827365E7 -1.26E7 -0.68 -0.8758 -0.9955 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C08 compound treatment 8.6192894E7 -3730000.0 -0.19 8.3814614E7 -1.26E7 -0.68 -0.6154 -0.8723 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C09 compound treatment 8.0682719E7 -9240000.0 -0.47 7.9619084E7 -1.68E7 -0.91 -0.9749 -0.9544 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C10 compound treatment 6.2831899E7 -2.71E7 -1.39 6.1356928E7 -3.51E7 -1.89 -2.3172 -0.9886 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C11 mock treatment 8.3137988E7 -6790000.0 -0.35 8.190421E7 -1.45E7 -0.78 -0.7989 -0.9334 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C12 mock treatment 7.6759024E7 -1.32E7 -0.67 8.093536E7 -1.55E7 -0.83 -1.0669 -0.9945 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C13 compound treatment 2.5572015E7 -6.44E7 -3.3 2.692521E7 -6.95E7 -3.74 -4.9786 -0.998 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C14 compound treatment 7.4382654E7 -1.55E7 -0.8 8.2493245E7 -1.39E7 -0.75 -1.0937 -0.9996 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C15 mock treatment 6.7369426E7 -2.26E7 -1.16 7.3958464E7 -2.25E7 -1.21 -1.6729 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C16 mock treatment 6.6229671E7 -2.37E7 -1.21 7.0909371E7 -2.55E7 -1.37 -1.8303 -0.9981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C17 compound treatment 2.6287043E7 -6.36E7 -3.26 2.6959662E7 -6.95E7 -3.74 -4.9514 -0.9977 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C18 compound treatment 7.8220557E7 -1.17E7 -0.6 8.9023265E7 -7400000.0 -0.4 -0.706 -0.9803 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C19 compound treatment 2.7478626E7 -6.24E7 -3.2 2.8294439E7 -6.81E7 -3.67 -4.8574 -0.9977 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C20 compound treatment 8.4383158E7 -5540000.0 -0.28 8.9007994E7 -7420000.0 -0.4 -0.4832 -0.986 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C21 compound treatment 8.080779E7 -9120000.0 -0.47 9.1398507E7 -5030000.0 -0.27 -0.5218 -0.9663 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C22 compound treatment 8.5794922E7 -4130000.0 -0.21 9.3986494E7 -2440000.0 -0.13 -0.2425 -0.9737 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C23 compound treatment 8.9152209E7 -772000.0 -0.04 9.7001203E7 576000.0 0.03 -0.006 -0.1202 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 C24 compound treatment 1.13316644E8 2.34E7 1.2 1.186332E8 2.22E7 1.2 1.6934 1.0 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D01 compound treatment 1.04680285E8 1.48E7 0.76 1.07446719E8 1.1E7 0.59 0.9545 0.9928 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D02 compound treatment 2.6784961E7 -6.31E7 -3.24 2.8085763E7 -6.83E7 -3.68 -4.8905 -0.9979 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D03 compound treatment 9.6445099E7 6520000.0 0.33 1.02896834E8 6470000.0 0.35 0.4828 0.9998 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D04 compound treatment 8.7998372E7 -1930000.0 -0.1 8.4232812E7 -1.22E7 -0.66 -0.5341 -0.8044 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D05 compound treatment 8.7513754E7 -2410000.0 -0.12 9.6990914E7 566000.0 0.03 -0.0658 -0.5173 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D06 compound treatment 4.7512128E7 -4.24E7 -2.17 5.0322157E7 -4.61E7 -2.48 -3.2926 -0.9978 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D07 compound treatment 8.7726431E7 -2200000.0 -0.11 8.2247912E7 -1.42E7 -0.76 -0.6195 -0.8027 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D08 compound treatment 5.3750986E7 -3.62E7 -1.85 5.4084406E7 -4.23E7 -2.28 -2.9232 -0.9947 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D09 compound treatment 8.1269544E7 -8650000.0 -0.44 8.554193E7 -1.09E7 -0.59 -0.7281 -0.9906 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D10 compound treatment 2.8906176E7 -6.1E7 -3.13 2.9456895E7 -6.7E7 -3.61 -4.7614 -0.9975 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D11 mock treatment 7.9919955E7 -1.0E7 -0.51 8.1510316E7 -1.49E7 -0.8 -0.9305 -0.9765 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D12 mock treatment 8.2430607E7 -7490000.0 -0.38 8.6378931E7 -1.0E7 -0.54 -0.6541 -0.9859 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D13 compound treatment 7.8655486E7 -1.13E7 -0.58 8.262057E7 -1.38E7 -0.74 -0.934 -0.9922 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D14 compound treatment 3.4280063E7 -5.56E7 -2.85 3.7365577E7 -5.91E7 -3.18 -4.2655 -0.9985 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D15 mock treatment 7.3272205E7 -1.67E7 -0.85 8.5078297E7 -1.13E7 -0.61 -1.0356 -0.9866 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D16 mock treatment 7.7402843E7 -1.25E7 -0.64 8.5866245E7 -1.06E7 -0.57 -0.8559 -0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D17 compound treatment 6.9424147E7 -2.05E7 -1.05 7.8721952E7 -1.77E7 -0.95 -1.4171 -0.9988 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D18 compound treatment 4.8993791E7 -4.09E7 -2.1 5.1105261E7 -4.53E7 -2.44 -3.2091 -0.9972 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D19 compound treatment 7.4959557E7 -1.5E7 -0.77 8.6186009E7 -1.02E7 -0.55 -0.9322 -0.9869 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D20 compound treatment 7.2257744E7 -1.77E7 -0.91 7.8066546E7 -1.84E7 -0.99 -1.3393 -0.999 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D21 compound treatment 8.0204134E7 -9720000.0 -0.5 8.9425961E7 -7000000.0 -0.38 -0.6188 -0.9905 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D22 compound treatment 7.1482351E7 -1.84E7 -0.95 7.198254E7 -2.44E7 -1.32 -1.5991 -0.9868 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D23 compound treatment 7.7682517E7 -1.22E7 -0.63 7.9307132E7 -1.71E7 -0.92 -1.0955 -0.9824 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 D24 compound treatment 2.6448266E7 -6.35E7 -3.25 2.7775628E7 -6.86E7 -3.7 -4.9145 -0.998 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E01 mock treatment 1.05985375E8 1.61E7 0.82 1.06196418E8 9770000.0 0.53 0.9541 0.9766 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E02 mock treatment 1.00141261E8 1.02E7 0.52 1.07561972E8 1.11E7 0.6 0.7943 0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E03 compound treatment 9.5761165E7 5840000.0 0.3 9.4642607E7 -1780000.0 -0.1 0.1437 0.4572 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E04 compound treatment 9.8103099E7 8180000.0 0.42 1.02943964E8 6520000.0 0.35 0.5446 0.9961 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E05 compound treatment 8.3868809E7 -6060000.0 -0.31 9.033558E7 -6090000.0 -0.33 -0.4513 -0.9996 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E06 compound treatment 9.3040821E7 3120000.0 0.16 9.4388104E7 -2040000.0 -0.11 0.0354 0.1826 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E07 compound treatment 7.865482E7 -1.13E7 -0.58 8.1303348E7 -1.51E7 -0.81 -0.9842 -0.9858 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E08 compound treatment 9.0395888E7 472000.0 0.02 8.9423266E7 -7000000.0 -0.38 -0.2495 -0.6604 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E09 mock treatment 8.5650941E7 -4270000.0 -0.22 8.3151064E7 -1.33E7 -0.71 -0.6603 -0.8832 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E10 mock treatment 8.0705075E7 -9220000.0 -0.47 8.4803099E7 -1.16E7 -0.63 -0.7767 -0.9904 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E11 compound treatment 7.3534309E7 -1.64E7 -0.84 7.7734839E7 -1.87E7 -1.01 -1.3057 -0.996 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E12 compound treatment 5.2499452E7 -3.74E7 -1.92 5.5823046E7 -4.06E7 -2.19 -2.9024 -0.9979 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E13 compound treatment 7.7380462E7 -1.25E7 -0.64 8.5089798E7 -1.13E7 -0.61 -0.8862 -0.9997 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E14 compound treatment 4.6192699E7 -4.37E7 -2.24 5.0886374E7 -4.55E7 -2.45 -3.3189 -0.999 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E15 compound treatment 7.5310228E7 -1.46E7 -0.75 8.2567148E7 -1.39E7 -0.75 -1.0573 -1.0 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E16 compound treatment 4.4985569E7 -4.49E7 -2.3 5.0932022E7 -4.55E7 -2.45 -3.3609 -0.9995 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E17 mock treatment 8.0351757E7 -9570000.0 -0.49 8.9129784E7 -7300000.0 -0.39 -0.6247 -0.9939 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E18 mock treatment 8.3732822E7 -6190000.0 -0.32 9.1814116E7 -4610000.0 -0.25 -0.4 -0.9926 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E19 compound treatment 8.5734991E7 -4190000.0 -0.21 9.3830725E7 -2590000.0 -0.14 -0.2506 -0.9783 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E20 compound treatment 8.2949571E7 -6970000.0 -0.36 8.9454822E7 -6970000.0 -0.38 -0.5182 -0.9997 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E21 compound treatment 8.198179E7 -7940000.0 -0.41 8.4154222E7 -1.23E7 -0.66 -0.7551 -0.9729 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E22 compound treatment 9.7875336E7 7950000.0 0.41 1.04542165E8 8120000.0 0.44 0.5972 0.9994 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E23 compound treatment 9.4128854E7 4200000.0 0.22 9.9059635E7 2630000.0 0.14 0.2527 0.9794 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 E24 compound treatment 1.01636654E8 1.17E7 0.6 1.10567674E8 1.41E7 0.76 0.963 0.9931 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F01 mock treatment 1.1303296E8 2.31E7 1.18 1.16007219E8 1.96E7 1.05 1.5831 0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F02 mock treatment 1.0338711E8 1.35E7 0.69 1.0569686E8 9270000.0 0.5 0.841 0.9874 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F03 compound treatment 9.1901419E7 1980000.0 0.1 9.4298668E7 -2130000.0 -0.11 -0.0093 -0.0609 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F04 compound treatment 8.7791775E7 -2130000.0 -0.11 9.3962605E7 -2460000.0 -0.13 -0.1711 -0.9954 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F05 compound treatment 9.2811305E7 2890000.0 0.15 9.4789292E7 -1640000.0 -0.09 0.0423 0.2458 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F06 compound treatment 8.044086E7 -9480000.0 -0.49 8.8882468E7 -7540000.0 -0.41 -0.6309 -0.996 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F07 compound treatment 7.9806005E7 -1.01E7 -0.52 8.3283731E7 -1.31E7 -0.71 -0.8671 -0.9883 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F08 compound treatment 8.471918E7 -5200000.0 -0.27 8.8104858E7 -8320000.0 -0.45 -0.5055 -0.9693 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F09 mock treatment 8.800512E7 -1920000.0 -0.1 8.9529364E7 -6900000.0 -0.37 -0.3321 -0.8646 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F10 mock treatment 8.2566413E7 -7360000.0 -0.38 8.7230517E7 -9190000.0 -0.5 -0.6168 -0.991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F11 compound treatment 7.8312152E7 -1.16E7 -0.6 8.3112951E7 -1.33E7 -0.72 -0.9277 -0.9957 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F12 compound treatment 7.2836633E7 -1.71E7 -0.88 7.7448538E7 -1.9E7 -1.02 -1.3419 -0.997 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F13 compound treatment 7.9391234E7 -1.05E7 -0.54 8.6798156E7 -9630000.0 -0.52 -0.7483 -0.9998 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F14 compound treatment 7.4198275E7 -1.57E7 -0.81 8.0927259E7 -1.55E7 -0.83 -1.1601 -0.9998 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F15 compound treatment 7.3789212E7 -1.61E7 -0.83 8.1592025E7 -1.48E7 -0.8 -1.1496 -0.9998 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F16 compound treatment 5.3560769E7 -3.64E7 -1.86 5.9786764E7 -3.66E7 -1.97 -2.713 -0.9996 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F17 mock treatment 8.2603515E7 -7320000.0 -0.38 8.9403749E7 -7020000.0 -0.38 -0.5327 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F18 mock treatment 8.4421034E7 -5500000.0 -0.28 9.0876483E7 -5550000.0 -0.3 -0.4107 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F19 compound treatment 8.5887307E7 -4040000.0 -0.21 8.9847071E7 -6580000.0 -0.35 -0.3968 -0.9672 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F20 compound treatment 8.874113E7 -1180000.0 -0.06 9.6004868E7 -420000.0 -0.02 -0.0589 -0.9098 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F21 compound treatment 8.985385E7 -70200.0 0.0 9.4369085E7 -2060000.0 -0.11 -0.0808 -0.7297 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F22 compound treatment 8.7641751E7 -2280000.0 -0.12 9.1023684E7 -5400000.0 -0.29 -0.2884 -0.9199 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F23 compound treatment 8.6294067E7 -3630000.0 -0.19 9.3937696E7 -2490000.0 -0.13 -0.2263 -0.987 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 F24 compound treatment 1.05092141E8 1.52E7 0.78 1.11999797E8 1.56E7 0.84 1.1428 0.9993 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G01 compound treatment 1.10811871E8 2.09E7 1.07 1.11478282E8 1.51E7 0.81 1.3302 0.9906 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G02 compound treatment 8.9000029E7 -924000.0 -0.05 1.004399E8 4010000.0 0.22 0.1194 0.5394 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G03 mock treatment 9.3698913E7 3770000.0 0.19 1.03860782E8 7440000.0 0.4 0.4199 0.9443 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G04 mock treatment 9.604345E7 6120000.0 0.31 1.0325865E8 6830000.0 0.37 0.482 0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G05 compound treatment 9.6928592E7 7000000.0 0.36 9.852389E7 2100000.0 0.11 0.3338 0.8868 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G06 compound treatment 8.8195768E7 -1730000.0 -0.09 9.1347716E7 -5080000.0 -0.27 -0.256 -0.8906 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G07 compound treatment 8.4417521E7 -5510000.0 -0.28 8.7786078E7 -8640000.0 -0.47 -0.5285 -0.9713 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G08 compound treatment 8.6821245E7 -3100000.0 -0.16 8.7392945E7 -9030000.0 -0.49 -0.4564 -0.8918 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G09 compound treatment 8.468212E7 -5240000.0 -0.27 8.3015166E7 -1.34E7 -0.72 -0.7006 -0.9093 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G10 compound treatment 7.146943E7 -1.85E7 -0.95 7.3896657E7 -2.25E7 -1.21 -1.5267 -0.9924 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G11 compound treatment 8.042602E7 -9500000.0 -0.49 8.605909E7 -1.04E7 -0.56 -0.7389 -0.9977 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G12 compound treatment 2.8751604E7 -6.12E7 -3.14 3.0721528E7 -6.57E7 -3.54 -4.7188 -0.9982 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G13 compound treatment 8.3174849E7 -6750000.0 -0.35 9.1227974E7 -5200000.0 -0.28 -0.4425 -0.9945 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G14 compound treatment 7.5268456E7 -1.47E7 -0.75 8.3239905E7 -1.32E7 -0.71 -1.0332 -0.9996 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G15 compound treatment 7.7276708E7 -1.26E7 -0.65 8.8952558E7 -7470000.0 -0.4 -0.7429 -0.9737 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G16 compound treatment 8.1350459E7 -8570000.0 -0.44 8.9846875E7 -6580000.0 -0.35 -0.5612 -0.9943 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G17 compound treatment 8.2877333E7 -7050000.0 -0.36 9.0634977E7 -5790000.0 -0.31 -0.4759 -0.9973 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G18 compound treatment 8.6123867E7 -3800000.0 -0.19 9.5787848E7 -637000.0 -0.03 -0.162 -0.8191 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G19 mock treatment 8.6606355E7 -3320000.0 -0.17 9.3528565E7 -2900000.0 -0.16 -0.2305 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G20 mock treatment 9.0413939E7 490000.0 0.03 9.2642164E7 -3780000.0 -0.2 -0.1263 -0.6153 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G21 compound treatment 9.1734543E7 1810000.0 0.09 9.5372185E7 -1050000.0 -0.06 0.0255 0.2346 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G22 compound treatment 9.5985746E7 6060000.0 0.31 9.9303249E7 2880000.0 0.15 0.3293 0.9484 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G23 compound treatment 9.7143915E7 7220000.0 0.37 9.5764272E7 -661000.0 -0.04 0.2365 0.6361 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 G24 compound treatment 1.012042E8 1.13E7 0.58 1.10522749E8 1.41E7 0.76 0.9456 0.991 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H01 compound treatment 1.04219917E8 1.43E7 0.73 1.05039272E8 8610000.0 0.46 0.8461 0.9757 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H02 compound treatment 2.6570542E7 -6.34E7 -3.25 2.7817296E7 -6.86E7 -3.69 -4.9085 -0.9979 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H03 mock treatment 9.5620538E7 5700000.0 0.29 9.7836927E7 1410000.0 0.08 0.2602 0.8625 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H04 mock treatment 9.2466205E7 2540000.0 0.13 9.4533764E7 -1890000.0 -0.1 0.0201 0.1216 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H05 compound treatment 3.4035701E7 -5.59E7 -2.86 4.2910051E7 -5.35E7 -2.88 -4.0632 -1.0 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H06 compound treatment 5.4386258E7 -3.55E7 -1.82 5.829441E7 -3.81E7 -2.05 -2.7399 -0.9982 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H07 compound treatment 8.1698609E7 -8230000.0 -0.42 8.5208846E7 -1.12E7 -0.6 -0.7252 -0.9845 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H08 mock treatment 8.7693056E7 -2230000.0 -0.11 9.261541E7 -3810000.0 -0.21 -0.2259 -0.9619 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H09 compound treatment 4.5942337E7 -4.4E7 -2.25 4.5395004E7 -5.1E7 -2.75 -3.5371 -0.9952 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H10 mock treatment 8.8498867E7 -1430000.0 -0.07 9.0494645E7 -5930000.0 -0.32 -0.2775 -0.847 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H11 compound treatment 7.6134807E7 -1.38E7 -0.71 7.9423366E7 -1.7E7 -0.92 -1.1471 -0.9918 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H12 mock treatment 8.1382746E7 -8540000.0 -0.44 8.688925E7 -9540000.0 -0.51 -0.6727 -0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H13 compound treatment 7.9553295E7 -1.04E7 -0.53 8.6790158E7 -9640000.0 -0.52 -0.7427 -0.9999 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H14 mock treatment 8.2713402E7 -7210000.0 -0.37 9.0846133E7 -5580000.0 -0.3 -0.4738 -0.9947 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H15 compound treatment 8.1495188E7 -8430000.0 -0.43 8.928219E7 -7140000.0 -0.38 -0.5775 -0.9983 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H16 mock treatment 7.9798297E7 -1.01E7 -0.52 8.7321869E7 -9100000.0 -0.49 -0.7136 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H17 compound treatment 8.539166E7 -4530000.0 -0.23 9.2605427E7 -3820000.0 -0.21 -0.3097 -0.9982 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H18 mock treatment 8.5508659E7 -4420000.0 -0.23 9.4322915E7 -2100000.0 -0.11 -0.2401 -0.9488 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H19 mock treatment 9.0317728E7 394000.0 0.02 9.769972E7 1270000.0 0.07 0.0628 0.8779 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H20 mock treatment 8.8712482E7 -1210000.0 -0.06 9.3459394E7 -2970000.0 -0.16 -0.1568 -0.9153 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H21 compound treatment 8.8896101E7 -1030000.0 -0.05 9.4980786E7 -1440000.0 -0.08 -0.0923 -0.982 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H22 mock treatment 9.4290756E7 4370000.0 0.22 1.01652175E8 5230000.0 0.28 0.3573 0.9936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H23 compound treatment 9.8768189E7 8840000.0 0.45 1.03245993E8 6820000.0 0.37 0.5802 0.9946 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 H24 mock treatment 1.01055315E8 1.11E7 0.57 1.11443627E8 1.5E7 0.81 0.9753 0.9854 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I01 compound treatment 1.00811866E8 1.09E7 0.56 1.05111259E8 8690000.0 0.47 0.7253 0.9961 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I02 compound treatment 1.01359348E8 1.14E7 0.59 1.06691507E8 1.03E7 0.55 0.8053 0.9996 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I03 compound treatment 2.5273048E7 -6.47E7 -3.31 2.6602029E7 -6.98E7 -3.76 -5.0018 -0.998 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I04 compound treatment 6.7053511E7 -2.29E7 -1.17 7.0046181E7 -2.64E7 -1.42 -1.8333 -0.9954 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I05 mock treatment 9.1849244E7 1930000.0 0.1 9.6244985E7 -180000.0 -0.01 0.0629 0.6344 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I06 mock treatment 9.0095694E7 172000.0 0.01 9.4573274E7 -1850000.0 -0.1 -0.0643 -0.6422 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I07 compound treatment 9.2982602E7 3060000.0 0.16 9.4547285E7 -1880000.0 -0.1 0.0393 0.2108 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I08 compound treatment 5.3530247E7 -3.64E7 -1.87 5.5904123E7 -4.05E7 -2.18 -2.8619 -0.997 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I09 compound treatment 7.4068451E7 -1.59E7 -0.81 8.1295759E7 -1.51E7 -0.81 -1.1507 -1.0 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I10 compound treatment 5.2804255E7 -3.71E7 -1.9 5.5755088E7 -4.07E7 -2.19 -2.8939 -0.9975 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I11 compound treatment 8.5117404E7 -4810000.0 -0.25 9.278638E7 -3640000.0 -0.2 -0.3128 -0.9936 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I12 compound treatment 4.76124E7 -4.23E7 -2.17 5.0812221E7 -4.56E7 -2.46 -3.2703 -0.9981 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I13 compound treatment 7.818766E7 -1.17E7 -0.6 8.8204427E7 -8220000.0 -0.44 -0.7384 -0.9886 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I14 compound treatment 3.2966956E7 -5.7E7 -2.92 4.0214878E7 -5.62E7 -3.03 -4.2046 -0.9998 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I15 compound treatment 8.3243911E7 -6680000.0 -0.34 9.2705499E7 -3720000.0 -0.2 -0.3837 -0.9674 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I16 compound treatment 3.1445796E7 -5.85E7 -3.0 3.3506267E7 -6.29E7 -3.39 -4.5152 -0.9981 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I17 compound treatment 8.4107252E7 -5820000.0 -0.3 9.3022858E7 -3400000.0 -0.18 -0.3404 -0.9727 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I18 compound treatment 3.7839995E7 -5.21E7 -2.67 4.1009236E7 -5.54E7 -2.98 -3.9977 -0.9985 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I19 compound treatment 9.1224072E7 1300000.0 0.07 9.7243636E7 818000.0 0.04 0.0783 0.9799 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I20 compound treatment 3.0178714E7 -5.97E7 -3.06 3.1848985E7 -6.46E7 -3.48 -4.6242 -0.998 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I21 mock treatment 9.0553043E7 629000.0 0.03 9.3628518E7 -2800000.0 -0.15 -0.0837 -0.5434 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I22 mock treatment 9.1634634E7 1710000.0 0.09 9.668246E7 257000.0 0.01 0.0718 0.8088 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I23 compound treatment 6.9866401E7 -2.01E7 -1.03 7.749731E7 -1.89E7 -1.02 -1.4477 -1.0 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 I24 compound treatment 3.5581564E7 -5.43E7 -2.79 3.7352794E7 -5.91E7 -3.18 -4.2188 -0.9978 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J01 compound treatment 1.08841742E8 1.89E7 0.97 1.10344823E8 1.39E7 0.75 1.2156 0.9919 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J02 mock treatment 1.0206663E8 1.21E7 0.62 1.0633856E8 9910000.0 0.53 0.8175 0.9971 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J03 compound treatment 9.1008658E7 1080000.0 0.06 9.3873195E7 -2550000.0 -0.14 -0.0579 -0.3904 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J04 mock treatment 9.4673159E7 4750000.0 0.24 9.8808991E7 2380000.0 0.13 0.2629 0.9553 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J05 mock treatment 9.236386E7 2440000.0 0.13 9.863407E7 2210000.0 0.12 0.1725 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J06 mock treatment 9.1640246E7 1720000.0 0.09 1.00754018E8 4330000.0 0.23 0.227 0.9112 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J07 compound treatment 8.1984324E7 -7940000.0 -0.41 8.4314084E7 -1.21E7 -0.65 -0.7489 -0.9742 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J08 mock treatment 8.9396603E7 -527000.0 -0.03 9.0502782E7 -5920000.0 -0.32 -0.2446 -0.7643 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J09 compound treatment 8.9090049E7 -834000.0 -0.04 9.5630991E7 -794000.0 -0.04 -0.0605 -1.0 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J10 mock treatment 8.2267722E7 -7660000.0 -0.39 9.1597404E7 -4830000.0 -0.26 -0.4613 -0.98 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J11 compound treatment 8.0853842E7 -9070000.0 -0.46 8.6425234E7 -1.0E7 -0.54 -0.7095 -0.9973 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J12 mock treatment 8.9054276E7 -870000.0 -0.04 9.3145061E7 -3280000.0 -0.18 -0.1564 -0.8586 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J13 compound treatment 8.3033239E7 -6890000.0 -0.35 9.2184702E7 -4240000.0 -0.23 -0.4112 -0.9777 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J14 mock treatment 8.4656311E7 -5270000.0 -0.27 9.1303672E7 -5120000.0 -0.28 -0.3859 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J15 compound treatment 8.0446552E7 -9480000.0 -0.49 8.5188973E7 -1.12E7 -0.61 -0.7713 -0.9941 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J16 mock treatment 8.2413978E7 -7510000.0 -0.38 8.9467977E7 -6960000.0 -0.37 -0.5371 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J17 compound treatment 8.5774374E7 -4150000.0 -0.21 9.4776712E7 -1650000.0 -0.09 -0.2132 -0.9249 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J18 mock treatment 8.5907841E7 -4020000.0 -0.21 9.1708694E7 -4720000.0 -0.25 -0.3252 -0.9946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J19 compound treatment 7.6043124E7 -1.39E7 -0.71 8.3844781E7 -1.26E7 -0.68 -0.9821 -0.9997 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J20 mock treatment 8.9126255E7 -798000.0 -0.04 9.9321806E7 2900000.0 0.16 0.0814 0.5047 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J21 mock treatment 8.9334822E7 -589000.0 -0.03 9.6814844E7 390000.0 0.02 -0.0065 -0.1774 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J22 mock treatment 9.4259085E7 4340000.0 0.22 9.3293447E7 -3130000.0 -0.17 0.0378 0.1357 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J23 compound treatment 9.4749729E7 4830000.0 0.25 1.01356527E8 4930000.0 0.27 0.3627 0.9994 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 J24 mock treatment 1.09389139E8 1.95E7 1.0 1.12244451E8 1.58E7 0.85 1.3078 0.9969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K01 compound treatment 2.6797764E7 -6.31E7 -3.24 2.7745768E7 -6.87E7 -3.7 -4.903 -0.9978 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K02 compound treatment 3.2228376E7 -5.77E7 -2.96 3.3984017E7 -6.24E7 -3.36 -4.4686 -0.9979 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K03 compound treatment 2.536445E7 -6.46E7 -3.31 2.6724717E7 -6.97E7 -3.75 -4.9938 -0.998 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K04 compound treatment 3.2376119E7 -5.75E7 -2.95 3.3934997E7 -6.25E7 -3.37 -4.4651 -0.9978 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K05 compound treatment 3.8364568E7 -5.16E7 -2.64 4.3052553E7 -5.34E7 -2.87 -3.9009 -0.9991 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K06 compound treatment 2.7198733E7 -6.27E7 -3.21 2.8535986E7 -6.79E7 -3.66 -4.8583 -0.9979 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K07 mock treatment 8.9342511E7 -582000.0 -0.03 9.1445763E7 -4980000.0 -0.27 -0.2107 -0.7809 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K08 mock treatment 8.5234243E7 -4690000.0 -0.24 9.1314764E7 -5110000.0 -0.28 -0.3646 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K09 compound treatment 9.3383398E7 3460000.0 0.18 9.6703273E7 278000.0 0.01 0.136 0.7641 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K10 compound treatment 7.0743911E7 -1.92E7 -0.98 7.8471685E7 -1.8E7 -0.97 -1.3788 -1.0 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K11 compound treatment 7.4782758E7 -1.51E7 -0.78 8.1157346E7 -1.53E7 -0.82 -1.1301 -0.9996 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K12 compound treatment 8.4538861E7 -5390000.0 -0.28 8.9794093E7 -6630000.0 -0.36 -0.4477 -0.9919 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K13 compound treatment 8.9023625E7 -900000.0 -0.05 9.3233769E7 -3190000.0 -0.17 -0.1542 -0.8663 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K14 compound treatment 7.7538328E7 -1.24E7 -0.63 8.6351449E7 -1.01E7 -0.54 -0.8325 -0.9969 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K15 mock treatment 8.1032647E7 -8890000.0 -0.46 9.0202589E7 -6220000.0 -0.34 -0.5592 -0.9886 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K16 mock treatment 8.2759916E7 -7160000.0 -0.37 9.2369059E7 -4060000.0 -0.22 -0.4141 -0.9692 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K17 compound treatment 8.2575327E7 -7350000.0 -0.38 9.2538712E7 -3890000.0 -0.21 -0.4143 -0.9616 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K18 compound treatment 7.9892562E7 -1.0E7 -0.51 8.8765741E7 -7660000.0 -0.41 -0.6552 -0.994 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K19 compound treatment 8.5839026E7 -4090000.0 -0.21 9.6147829E7 -278000.0 -0.01 -0.1586 -0.7557 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K20 compound treatment 8.7757965E7 -2170000.0 -0.11 9.3942699E7 -2480000.0 -0.13 -0.173 -0.9957 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K21 compound treatment 8.5483965E7 -4440000.0 -0.23 9.0641159E7 -5780000.0 -0.31 -0.3812 -0.9881 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K22 compound treatment 8.5576471E7 -4350000.0 -0.22 8.5760337E7 -1.07E7 -0.57 -0.5637 -0.915 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K23 mock treatment 9.6814042E7 6890000.0 0.35 9.6910277E7 485000.0 0.03 0.2682 0.7573 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 K24 mock treatment 1.02308248E8 1.24E7 0.63 1.0751514E8 1.11E7 0.6 0.8711 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L01 compound treatment 1.1423982E8 2.43E7 1.25 1.13851291E8 1.74E7 0.94 1.5448 0.9902 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L02 mock treatment 9.5758463E7 5830000.0 0.3 9.5337823E7 -1090000.0 -0.06 0.17 0.558 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L03 compound treatment 1.00352916E8 1.04E7 0.53 1.04261451E8 7840000.0 0.42 0.6763 0.9932 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L04 mock treatment 9.0063731E7 140000.0 0.01 1.01156086E8 4730000.0 0.25 0.1852 0.7267 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L05 compound treatment 9.8375766E7 8450000.0 0.43 9.7050206E7 625000.0 0.03 0.3301 0.7597 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L06 mock treatment 9.3660715E7 3740000.0 0.19 1.00221554E8 3800000.0 0.2 0.28 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L07 mock treatment 8.8832444E7 -1090000.0 -0.06 9.4212198E7 -2210000.0 -0.12 -0.1238 -0.9406 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L08 mock treatment 8.5996288E7 -3930000.0 -0.2 9.0681581E7 -5740000.0 -0.31 -0.3611 -0.9784 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L09 compound treatment 8.4870222E7 -5050000.0 -0.26 9.0674814E7 -5750000.0 -0.31 -0.4021 -0.9961 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L10 mock treatment 8.7332579E7 -2590000.0 -0.13 9.7507542E7 1080000.0 0.06 -0.0527 -0.3634 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L11 compound treatment 8.3806591E7 -6120000.0 -0.31 9.2730897E7 -3690000.0 -0.2 -0.3624 -0.9759 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L12 mock treatment 8.5442895E7 -4480000.0 -0.23 9.2051051E7 -4370000.0 -0.24 -0.329 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L13 compound treatment 8.1506044E7 -8420000.0 -0.43 8.9582076E7 -6840000.0 -0.37 -0.5657 -0.9969 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L14 mock treatment 8.3189655E7 -6730000.0 -0.35 9.0106878E7 -6320000.0 -0.34 -0.4847 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L15 mock treatment 8.0366558E7 -9560000.0 -0.49 9.3204265E7 -3220000.0 -0.17 -0.469 -0.9026 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L16 mock treatment 8.0838907E7 -9090000.0 -0.47 9.4502104E7 -1920000.0 -0.1 -0.4025 -0.8438 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L17 compound treatment 8.5461764E7 -4460000.0 -0.23 9.6408009E7 -17300.0 0.0 -0.1624 -0.71 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L18 mock treatment 8.3715562E7 -6210000.0 -0.32 9.5706798E7 -719000.0 -0.04 -0.2524 -0.7873 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L19 compound treatment 9.0842431E7 918000.0 0.05 9.990887E7 3480000.0 0.19 0.1659 0.8579 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L20 mock treatment 9.5281262E7 5360000.0 0.27 1.0323689E8 6810000.0 0.37 0.4535 0.9898 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L21 compound treatment 8.8744203E7 -1180000.0 -0.06 9.5826112E7 -599000.0 -0.03 -0.0656 -0.9567 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L22 mock treatment 8.6576176E7 -3350000.0 -0.17 9.1092393E7 -5330000.0 -0.29 -0.3244 -0.9697 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L23 mock treatment 9.6883083E7 6960000.0 0.36 9.6074357E7 -351000.0 -0.02 0.2388 0.6687 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 L24 mock treatment 1.06206815E8 1.63E7 0.83 1.05614096E8 9190000.0 0.49 0.94 0.9689 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M01 compound treatment 2.6719619E7 -6.32E7 -3.24 2.7955325E7 -6.85E7 -3.69 -4.8978 -0.9979 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M02 compound treatment 9.0288399E7 364000.0 0.02 9.1146545E7 -5280000.0 -0.28 -0.1878 -0.6592 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M03 compound treatment 7.9821043E7 -1.01E7 -0.52 8.9951108E7 -6470000.0 -0.35 -0.6127 -0.9815 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M04 compound treatment 8.7772822E7 -2150000.0 -0.11 9.7531451E7 1110000.0 0.06 -0.0358 -0.286 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M05 compound treatment 2.5101238E7 -6.48E7 -3.32 2.6621111E7 -6.98E7 -3.76 -5.0073 -0.9981 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M06 compound treatment 8.6782726E7 -3140000.0 -0.16 9.749678E7 1070000.0 0.06 -0.073 -0.4271 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M07 compound treatment 8.7197292E7 -2730000.0 -0.14 9.1929548E7 -4500000.0 -0.24 -0.27 -0.9659 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M08 compound treatment 8.4772229E7 -5150000.0 -0.26 8.8160338E7 -8260000.0 -0.45 -0.5014 -0.9689 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M09 mock treatment 9.1040836E7 1120000.0 0.06 1.00368014E8 3940000.0 0.21 0.1906 0.8668 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M10 mock treatment 8.7901972E7 -2020000.0 -0.1 9.8773767E7 2350000.0 0.13 0.0161 0.0987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M11 compound treatment 7.656006E7 -1.34E7 -0.68 8.6148821E7 -1.03E7 -0.55 -0.8756 -0.9944 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M12 compound treatment 8.1760927E7 -8160000.0 -0.42 8.6538987E7 -9890000.0 -0.53 -0.6723 -0.9929 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M13 mock treatment 8.318521E7 -6740000.0 -0.35 9.5009229E7 -1420000.0 -0.08 -0.2981 -0.8429 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M14 mock treatment 8.1860437E7 -8060000.0 -0.41 9.8738719E7 2310000.0 0.12 -0.2041 -0.4729 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M15 compound treatment 6.3021268E7 -2.69E7 -1.38 7.6293921E7 -2.01E7 -1.08 -1.7416 -0.9929 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M16 compound treatment 7.6971817E7 -1.3E7 -0.66 8.5707522E7 -1.07E7 -0.58 -0.8775 -0.9976 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M17 compound treatment 7.0371094E7 -1.96E7 -1.0 8.3153725E7 -1.33E7 -0.71 -1.214 -0.9863 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M18 compound treatment 7.1435821E7 -1.85E7 -0.95 8.7684021E7 -8740000.0 -0.47 -1.0029 -0.9479 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M19 compound treatment 8.5274193E7 -4650000.0 -0.24 9.5206519E7 -1220000.0 -0.07 -0.2149 -0.8695 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M20 compound treatment 6.3525436E7 -2.64E7 -1.35 7.7378109E7 -1.9E7 -1.03 -1.682 -0.9907 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M21 compound treatment 9.2999084E7 3080000.0 0.16 1.00692039E8 4270000.0 0.23 0.2739 0.9831 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M22 compound treatment 6.5674768E7 -2.42E7 -1.24 6.474451E7 -3.17E7 -1.71 -2.0852 -0.9879 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M23 compound treatment 8.2631309E7 -7290000.0 -0.37 9.1919092E7 -4510000.0 -0.24 -0.4359 -0.9781 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 M24 compound treatment 5.3770938E7 -3.62E7 -1.85 5.5543274E7 -4.09E7 -2.2 -2.8669 -0.9963 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N01 compound treatment 1.07358498E8 1.74E7 0.89 1.07961571E8 1.15E7 0.62 1.0711 0.9842 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N02 mock treatment 1.11101781E8 2.12E7 1.09 1.1440608E8 1.8E7 0.97 1.4522 0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N03 compound treatment 9.7294659E7 7370000.0 0.38 1.11366208E8 1.49E7 0.8 0.836 0.9406 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N04 mock treatment 1.02194456E8 1.23E7 0.63 1.07797934E8 1.14E7 0.61 0.8777 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N05 compound treatment 8.9150416E7 -774000.0 -0.04 9.6800721E7 375000.0 0.02 -0.0137 -0.3088 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N06 mock treatment 9.6971278E7 7050000.0 0.36 1.01244815E8 4820000.0 0.26 0.4389 0.9869 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N07 compound treatment 8.797032E7 -1950000.0 -0.1 1.03382353E8 6960000.0 0.37 0.1941 0.5005 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N08 mock treatment 9.2451739E7 2530000.0 0.13 1.03881677E8 7460000.0 0.4 0.3755 0.8901 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N09 mock treatment 9.3188063E7 3260000.0 0.17 1.01342979E8 4920000.0 0.26 0.3055 0.9755 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N10 mock treatment 8.7937764E7 -1990000.0 -0.1 9.7517014E7 1090000.0 0.06 -0.0304 -0.2587 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N11 compound treatment 8.3036614E7 -6890000.0 -0.35 9.4565233E7 -1860000.0 -0.1 -0.3204 -0.8733 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N12 mock treatment 9.0353842E7 430000.0 0.02 9.5448284E7 -977000.0 -0.05 -0.0216 -0.3792 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N13 mock treatment 8.7816009E7 -2110000.0 -0.11 9.70925E7 667000.0 0.04 -0.051 -0.4479 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N14 mock treatment 8.7790824E7 -2130000.0 -0.11 9.9800475E7 3380000.0 0.18 0.0512 0.2414 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N15 compound treatment 8.3283062E7 -6640000.0 -0.34 1.01352658E8 4930000.0 0.27 -0.0531 -0.1229 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N16 mock treatment 9.5175713E7 5250000.0 0.27 1.01576136E8 5150000.0 0.28 0.3865 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N17 compound treatment 8.892726E7 -997000.0 -0.05 1.04367731E8 7940000.0 0.43 0.2663 0.6183 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N18 mock treatment 8.6061009E7 -3860000.0 -0.2 1.01860629E8 5440000.0 0.29 0.067 0.1895 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N19 compound treatment 2.8530984E7 -6.14E7 -3.15 2.9716891E7 -6.67E7 -3.59 -4.7651 -0.9978 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N20 mock treatment 9.7785381E7 7860000.0 0.4 1.05274739E8 8850000.0 0.48 0.6219 0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N21 compound treatment 6.9305847E7 -2.06E7 -1.06 6.3092055E7 -3.33E7 -1.8 -2.0165 -0.9681 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N22 mock treatment 8.5631581E7 -4290000.0 -0.22 9.5573696E7 -852000.0 -0.05 -0.188 -0.8365 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N23 compound treatment 8.422291E7 -5700000.0 -0.29 8.942001E7 -7010000.0 -0.38 -0.4734 -0.992 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 N24 mock treatment 1.02860038E8 1.29E7 0.66 1.07205197E8 1.08E7 0.58 0.8793 0.9978 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O01 compound treatment 3.1942149E7 -5.8E7 -2.97 3.3135043E7 -6.33E7 -3.41 -4.5113 -0.9977 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O02 compound treatment 1.01552484E8 1.16E7 0.6 1.0522352E8 8800000.0 0.47 0.7564 0.9935 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O03 compound treatment 9.5677858E7 5750000.0 0.29 9.9329795E7 2900000.0 0.16 0.3191 0.956 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O04 compound treatment 9.9239425E7 9320000.0 0.48 1.09639947E8 1.32E7 0.71 0.8408 0.9812 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O05 compound treatment 8.0515478E7 -9410000.0 -0.48 9.9341376E7 2920000.0 0.16 -0.2299 -0.4534 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O06 compound treatment 8.4436033E7 -5490000.0 -0.28 8.7678021E7 -8750000.0 -0.47 -0.532 -0.9696 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O07 compound treatment 9.215214E7 2230000.0 0.11 1.03963032E8 7540000.0 0.41 0.3678 0.8722 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O08 compound treatment 8.7217955E7 -2710000.0 -0.14 9.9030387E7 2610000.0 0.14 0.0011 0.0057 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O09 compound treatment 9.1879782E7 1960000.0 0.1 1.05055217E8 8630000.0 0.46 0.3995 0.8403 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O10 compound treatment 8.940223E7 -522000.0 -0.03 1.04077607E8 7650000.0 0.41 0.2725 0.6598 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O11 mock treatment 9.1891999E7 1970000.0 0.1 1.04293553E8 7870000.0 0.42 0.3709 0.8516 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O12 mock treatment 8.7802766E7 -2120000.0 -0.11 1.03356077E8 6930000.0 0.37 0.187 0.4811 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O13 compound treatment 9.246616E7 2540000.0 0.13 1.04968531E8 8540000.0 0.46 0.4174 0.873 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O14 compound treatment 9.274452E7 2820000.0 0.14 9.7130172E7 705000.0 0.04 0.1291 0.8635 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O15 compound treatment 9.9668924E7 9740000.0 0.5 1.12451785E8 1.6E7 0.86 0.9634 0.9662 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O16 compound treatment 8.9247224E7 -677000.0 -0.03 1.05672427E8 9250000.0 0.5 0.3276 0.6563 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O17 compound treatment 9.8083533E7 8160000.0 0.42 1.16836873E8 2.04E7 1.1 1.0729 0.9123 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O18 compound treatment 8.9036037E7 -888000.0 -0.05 1.07415971E8 1.1E7 0.59 0.3863 0.6508 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O19 compound treatment 8.4432328E7 -5490000.0 -0.28 9.9653243E7 3230000.0 0.17 -0.0761 -0.2301 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O20 compound treatment 7.5567494E7 -1.44E7 -0.74 8.1267593E7 -1.52E7 -0.82 -1.0975 -0.9987 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O21 compound treatment 1.05471491E8 1.55E7 0.8 1.11996381E8 1.56E7 0.84 1.1564 0.9997 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O22 compound treatment 8.8319118E7 -1600000.0 -0.08 9.1634649E7 -4790000.0 -0.26 -0.2406 -0.8885 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O23 compound treatment 1.01214682E8 1.13E7 0.58 1.06512565E8 1.01E7 0.54 0.7933 0.9995 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 O24 compound treatment 9.4301235E7 4380000.0 0.22 1.00715569E8 4290000.0 0.23 0.322 0.9999 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P01 compound treatment 9.1400834E7 1480000.0 0.08 9.8355778E7 1930000.0 0.1 0.127 0.9878 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P02 mock treatment 1.0810286E8 1.82E7 0.93 1.13003943E8 1.66E7 0.89 1.2901 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P03 compound treatment 9.2532385E7 2610000.0 0.13 9.7470837E7 1050000.0 0.06 0.1343 0.9261 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P04 mock treatment 1.02306313E8 1.24E7 0.63 1.05745835E8 9320000.0 0.5 0.8037 0.9933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P05 compound treatment 1.08299456E8 1.84E7 0.94 1.14876105E8 1.85E7 0.99 1.3685 0.9996 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P06 mock treatment 9.8677201E7 8750000.0 0.45 1.12821068E8 1.64E7 0.88 0.9415 0.9507 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P07 compound treatment 1.03511776E8 1.36E7 0.7 1.14856246E8 1.84E7 0.99 1.1943 0.985 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P08 mock treatment 9.8545712E7 8620000.0 0.44 1.09036234E8 1.26E7 0.68 0.7927 0.9783 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P09 compound treatment 9.2095079E7 2170000.0 0.11 1.07675663E8 1.13E7 0.61 0.5071 0.8232 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P10 mock treatment 1.02301549E8 1.24E7 0.63 1.17211519E8 2.08E7 1.12 1.2401 0.9638 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P11 mock treatment 1.00638941E8 1.07E7 0.55 1.15226001E8 1.88E7 1.01 1.1042 0.9587 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P12 mock treatment 9.7646943E7 7720000.0 0.4 1.06614329E8 1.02E7 0.55 0.6679 0.9872 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P13 compound treatment 8.0188641E7 -9740000.0 -0.5 9.717788E7 753000.0 0.04 -0.3242 -0.6475 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P14 mock treatment 9.1658193E7 1730000.0 0.09 1.02383434E8 5960000.0 0.32 0.2897 0.8702 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P15 compound treatment 8.1760843E7 -8160000.0 -0.42 9.2594127E7 -3830000.0 -0.21 -0.4417 -0.9469 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P16 mock treatment 9.1106048E7 1180000.0 0.06 9.6782949E7 358000.0 0.02 0.0565 0.8881 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P17 compound treatment 6.7384367E7 -2.25E7 -1.16 7.5377169E7 -2.1E7 -1.13 -1.6183 -1.0 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P18 mock treatment 9.5002933E7 5080000.0 0.26 1.07286505E8 1.09E7 0.58 0.5976 0.9335 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P19 compound treatment 9.623647E7 6310000.0 0.32 1.07244691E8 1.08E7 0.58 0.6408 0.9615 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P20 mock treatment 9.492274E7 5000000.0 0.26 1.03073532E8 6650000.0 0.36 0.4343 0.9865 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P21 compound treatment 1.03518564E8 1.36E7 0.7 1.01056525E8 4630000.0 0.25 0.669 0.904 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P22 mock treatment 9.863119E7 8710000.0 0.45 1.01205968E8 4780000.0 0.26 0.4976 0.9658 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P23 compound treatment 1.03170214E8 1.32E7 0.68 1.01976451E8 5550000.0 0.3 0.6914 0.9321 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2283 P24 mock treatment 1.17585169E8 2.77E7 1.42 1.28825338E8 3.24E7 1.74 2.2362 0.9947 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A01 compound treatment 1.15691456E8 1.9E7 0.98 1.27209697E8 1.86E7 1.0 1.4 0.9999 3622978 BCB04_000001 COC(=O)c1ccc(CNC(=N)N)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A02 compound treatment 9.4281934E7 -2360000.0 -0.12 1.04969591E8 -3600000.0 -0.19 -0.2228 -0.9742 3622979 BCB04_000002 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)c2ccc(OC)c(OC)c2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A03 compound treatment 2.7597434E7 -6.9E7 -3.54 2.8516985E7 -8.01E7 -4.31 -5.5507 -0.9952 3622981 BCB04_000003 Nc1ccccc1NC(=O)c2ccc(CNc3nccc(n3)c4cccnc4)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A04 compound treatment 6.788661E7 -2.88E7 -1.47 8.0080052E7 -2.85E7 -1.53 -2.1271 -0.9998 3622982 BCB04_000004 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)c4ccc(OC)c(OC)c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A05 compound treatment 2.9483078E7 -6.72E7 -3.44 3.0584622E7 -7.8E7 -4.2 -5.4036 -0.9951 525 BCB04_000005 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccccc2N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A06 compound treatment 9.1802061E7 -4840000.0 -0.25 1.03494412E8 -5080000.0 -0.27 -0.3688 -0.9988 3622984 BCB04_000006 COC(=O)[C@@H](O)[C@H](c1ccc(OC)cc1)n2cc(nn2)c3ccc(OC)c(OC)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A07 compound treatment 9.2518402E7 -4120000.0 -0.21 1.03207246E8 -5370000.0 -0.29 -0.3538 -0.9882 3622986 BCB04_000007 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccccc2[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A08 compound treatment 9.561969E7 -1020000.0 -0.05 1.10943368E8 2370000.0 0.13 0.0532 0.3853 3622987 BCB04_000008 O=C1CC[C@H]2N1CCc3c2[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A09 compound treatment 2.8634745E7 -6.8E7 -3.49 2.9374642E7 -7.92E7 -4.26 -5.4804 -0.995 3622988 BCB04_000009 ONC(=O)/C=C/c1cccc(c1)S(=O)(=O)Nc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A10 compound treatment 9.2951562E7 -3690000.0 -0.19 1.07746752E8 -826000.0 -0.04 -0.1652 -0.8502 3622990 BCB04_000010 COc1ccc2[nH]c3[C@H]4CCC(=O)N4CCc3c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A11 compound treatment 2.8759446E7 -6.79E7 -3.48 2.9456603E7 -7.91E7 -4.26 -5.4728 -0.9949 3622992 BCB04_000011 CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(cc3)C(=O)NO)ccc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A12 compound treatment 8.7447966E7 -9190000.0 -0.47 1.04810667E8 -3760000.0 -0.2 -0.4765 -0.9289 3622993 BCB04_000012 Fc1ccc2[nH]c3[C@H]4CCC(=O)N4CCc3c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A13 mock treatment 9.2036917E7 -4610000.0 -0.24 1.14768232E8 6200000.0 0.33 0.069 0.1688 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A14 mock treatment 8.7320592E7 -9320000.0 -0.48 9.9896897E7 -8680000.0 -0.47 -0.6682 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A15 compound treatment 2.7663337E7 -6.9E7 -3.54 2.8458694E7 -8.01E7 -4.31 -5.5505 -0.9951 3622995 BCB04_000013 ONC(=O)CCCCCC(=O)Nc1cccnc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A16 compound treatment 9.3657128E7 -2990000.0 -0.15 1.05435925E8 -3140000.0 -0.17 -0.2277 -0.9988 3622996 BCB04_000014 Brc1ccc2[nH]c3[C@H]4CCC(=O)N4CCc3c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A17 compound treatment 2.8873395E7 -6.78E7 -3.47 2.9886563E7 -7.87E7 -4.24 -5.4523 -0.9951 3622998 BCB04_000015 OCCN(CCc1c[nH]c2ccccc12)Cc3ccc(/C=C/C(=O)NO)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A18 compound treatment 1.08678533E8 1.2E7 0.62 1.20817908E8 1.22E7 0.66 0.9024 0.9994 3623000 BCB04_000016 Cc1cccc2c3CCN4[C@H](CCC4=O)c3[nH]c12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A19 compound treatment 2.9514882E7 -6.71E7 -3.44 3.0352364E7 -7.82E7 -4.21 -5.4113 -0.995 3623002 BCB04_000017 Cc1[nH]c2ccccc2c1CCNCc3ccc(/C=C/C(=O)NO)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A20 compound treatment 9.5771187E7 -872000.0 -0.04 1.05721361E8 -2850000.0 -0.15 -0.1402 -0.8765 3623004 BCB04_000018 O=C1CCC[C@H]2N1CCc3c2[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A21 compound treatment 2.8055196E7 -6.86E7 -3.52 2.9058372E7 -7.95E7 -4.28 -5.5135 -0.9952 3623005 BCB04_000019 CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc3ccc(cc3)C(=O)NO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A22 compound treatment 1.03798068E8 7160000.0 0.37 1.14902785E8 6330000.0 0.34 0.5003 0.9993 3623006 BCB04_000020 C[C@@]12CCC(=O)N2CCc3c1[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A23 compound treatment 9.6639583E7 -3320.0 0.0 1.09917651E8 1340000.0 0.07 0.0511 0.7054 3615849 BCB04_000021 COc1cc2CCN(CC(C)O)CCCc3c(noc3-c2cc1OC)c4ccc(OCCO[Si](C(C)C)(C(C)C)C(C)C)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 A24 compound treatment 1.17833026E8 2.12E7 1.09 1.26283379E8 1.77E7 0.95 1.4423 0.9979 3623006 BCB04_000022 C[C@@]12CCC(=O)N2CCc3c1[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B01 compound treatment 1.19324878E8 2.27E7 1.16 1.25969836E8 1.74E7 0.94 1.4845 0.9943 3623008 BCB04_000023 CN1C(=O)N[C@H]2[C@@H](COC(=O)c3ccccc3)[C@]1(CO)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B02 compound treatment 9.9524025E7 2880000.0 0.15 1.08322962E8 -250000.0 -0.01 0.0949 0.64 3623010 BCB04_000024 CC(C)(C)OC(=O)N[C@@H]1CN(CC2=C1CC(COC(=O)c3ccccc3)C4=C2CN(C4)S(=O)(=O)c5ccc(Br)cc5)S(=O)(=O)c6ccccc6[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B03 compound treatment 8.1059111E7 -1.56E7 -0.8 8.5934588E7 -2.26E7 -1.22 -1.4268 -0.979 3623012 BCB04_000025 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N=C5SCc6ccccc6CN45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B04 compound treatment 8.941435E7 -7230000.0 -0.37 9.7907091E7 -1.07E7 -0.57 -0.6681 -0.9775 3623014 BCB04_000026 Cn1c(=O)n2CC(=C3CN(C[C@H](NC(=O)OC(C)(C)C)[C@H]3n2c1=O)S(=O)(=O)c4ccc(Br)cc4)COC(=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B05 compound treatment 6.8909116E7 -2.77E7 -1.42 7.7652818E7 -3.09E7 -1.67 -2.1825 -0.9969 3623016 BCB04_000027 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccccc5)N=C6SCc7ccccc7CN46)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B06 compound treatment 8.6687103E7 -9960000.0 -0.51 9.2465838E7 -1.61E7 -0.87 -0.9741 -0.968 3623018 BCB04_000028 Cn1c(=O)n2CC(=C3CN(C[C@H](NC(=O)OC(C)(C)C)[C@@H]3n2c1=O)S(=O)(=O)c4ccc(Br)cc4)COC(=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B07 compound treatment 2.9526462E7 -6.71E7 -3.44 3.1707289E7 -7.69E7 -4.14 -5.3593 -0.9958 3623019 BCB04_000029 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N=C5SCCCN45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B08 compound treatment 7.4942418E7 -2.17E7 -1.11 8.243718E7 -2.61E7 -1.41 -1.7817 -0.9932 3623021 BCB04_000030 Cn1c(=O)n2[C@@H]3[C@@H](COC(=O)c4ccccc4)N(CC3=C5CN(C[C@H](NC(=O)OC(C)(C)C)[C@@H]5n2c1=O)S(=O)(=O)c6ccccc6[N+](=O)[O-])S(=O)(=O)c7ccc(Br)cc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B09 compound treatment 8.3083874E7 -1.36E7 -0.69 9.4877277E7 -1.37E7 -0.74 -1.0129 -0.9996 3623023 BCB04_000031 OC[C@@]1(Oc2ccccc2[C@@H]3[C@H]1COC(=O)c4ccccc4)N=C5SCc6ccccc6CN35 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B10 compound treatment 7.1097726E7 -2.55E7 -1.31 9.3463335E7 -1.51E7 -0.81 -1.5011 -0.9738 3623025 BCB04_000032 Cn1c(=O)n2[C@@H]3[C@@H](COC(=O)c4ccccc4)N(CC3=C5CN(C[C@@H](NC(=O)OC(C)(C)C)[C@@H]5n2c1=O)S(=O)(=O)c6ccccc6[N+](=O)[O-])S(=O)(=O)c7ccc(Br)cc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B11 compound treatment 7.0212491E7 -2.64E7 -1.35 8.4378433E7 -2.42E7 -1.3 -1.8792 -0.9998 3623026 BCB04_000033 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N=C5SCCCN45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B12 compound treatment 7.7070159E7 -1.96E7 -1.0 9.7392671E7 -1.12E7 -0.6 -1.1351 -0.9702 3623028 BCB04_000034 Cn1c(=O)n2n(c1=O)C34CC(COC(=O)c5ccccc5)C62CN(CC6=C4CN(CC3NC(=O)OC(C)(C)C)S(=O)(=O)c7ccccc7[N+](=O)[O-])S(=O)(=O)c8ccc(Br)cc8 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B13 mock treatment 7.765769E7 -1.9E7 -0.97 9.2305918E7 -1.63E7 -0.88 -1.3075 -0.9986 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B14 mock treatment 7.8572335E7 -1.81E7 -0.93 9.3260997E7 -1.53E7 -0.82 -1.238 -0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B15 compound treatment 5.6310164E7 -4.03E7 -2.07 6.2342673E7 -4.62E7 -2.49 -3.2221 -0.9957 3623029 BCB04_000035 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccccc5)N=C6SCCCN46)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B16 compound treatment 7.5777397E7 -2.09E7 -1.07 9.4619563E7 -1.4E7 -0.75 -1.2875 -0.9851 3623031 BCB04_000036 CC(C)(C)OC(=O)N[C@H]1CN(CC2=C(COC(=O)c3ccccc3)C[C@@H]4[C@H]([C@@H]12)C(=O)N(C4=O)c5ccccc5)S(=O)(=O)c6ccc(Br)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B17 compound treatment 6.513098E7 -3.15E7 -1.62 6.5865861E7 -4.27E7 -2.3 -2.7682 -0.985 3623033 BCB04_000037 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccccc5)N(C)C(=O)N4C(=O)CC(=O)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B18 compound treatment 7.5819753E7 -2.08E7 -1.07 8.0685071E7 -2.79E7 -1.5 -1.8166 -0.986 3623035 BCB04_000038 CC(C)(C)OC(=O)N[C@H]1CN(CC2=C(COC(=O)c3ccccc3)C[C@H]4[C@@H]([C@H]12)C(=O)N(C4=O)c5ccccc5)S(=O)(=O)c6ccc(Br)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B19 compound treatment 8.4803638E7 -1.18E7 -0.61 9.2973087E7 -1.56E7 -0.84 -1.0231 -0.9873 3623036 BCB04_000039 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N(C)c5c6C(=O)N(C)C(=O)c6c(C(=O)C)c(=O)n45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B20 compound treatment 9.3501817E7 -3140000.0 -0.16 1.04740617E8 -3830000.0 -0.21 -0.2598 -0.9925 3623038 BCB04_000040 CC(C)(C)OC(=O)NCC1=C2CN([C@H](COC(=O)c3ccccc3)[C@@H]2[C@H]4[C@H](C1)C(=O)N(C4=O)c5ccccc5)S(=O)(=O)c6ccc(Br)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B21 compound treatment 9.1769381E7 -4870000.0 -0.25 1.00045421E8 -8530000.0 -0.46 -0.5013 -0.959 3623040 BCB04_000041 OC[C@@]1(Oc2ccccc2[C@@H]3[C@H]1COC(=O)c4ccccc4)N=C5SCCCN35 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B22 compound treatment 7.6123159E7 -2.05E7 -1.05 9.3289707E7 -1.53E7 -0.82 -1.3256 -0.9926 3623042 BCB04_000042 CC(C)(C)OC(=O)NCC1=C2CN([C@H](COC(=O)c3ccccc3)[C@H]2[C@@H]4[C@@H](C1)C(=O)N(C4=O)c5ccccc5)S(=O)(=O)c6ccc(Br)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B23 compound treatment 9.0374786E7 -6270000.0 -0.32 9.9563112E7 -9010000.0 -0.49 -0.5702 -0.98 3623043 BCB04_000043 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N=C5SCC(=O)N45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 B24 compound treatment 1.01191473E8 4550000.0 0.23 1.15299256E8 6730000.0 0.36 0.421 0.9773 3623045 BCB04_000044 CC(C)(C)OC(=O)N[C@H]1CN(CC2=C(COC(=O)c3ccccc3)C[C@@]4(Cl)C(Cl)(Cl)[C@@]4(Cl)[C@H]12)S(=O)(=O)c5ccc(Br)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C01 compound treatment 1.09598961E8 1.3E7 0.66 1.15195381E8 6620000.0 0.36 0.7217 0.9575 3623047 BCB04_000045 COc1cc2CCN(CC(C)O)CCCc3c(noc3-c2cc1OC)c4ccc(OCCO)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C02 compound treatment 9.8993084E7 2350000.0 0.12 1.07663114E8 -910000.0 -0.05 0.0505 0.3885 3623048 BCB04_000046 COc1ccc2[nH]c3c(CCN4C(=O)CC[C@@]43C)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C03 compound treatment 8.8531455E7 -8110000.0 -0.42 9.9274709E7 -9300000.0 -0.5 -0.648 -0.9957 3623049 BCB04_000047 COc1cc2CCN(CC=C)CCCc3c(noc3-c2cc1OC)c4ccc(OCCO)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C04 compound treatment 9.5775789E7 -867000.0 -0.04 1.067158E8 -1860000.0 -0.1 -0.1021 -0.9333 3623050 BCB04_000048 C[C@@]12C=CC(=O)N2CCc3c1[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C05 compound treatment 9.1993307E7 -4650000.0 -0.24 1.06307745E8 -2270000.0 -0.12 -0.2548 -0.9516 3556313 BCB04_000049 COc1cc2CCN3CC[C@H]4C(=NO[C@]43c2cc1OC)c5ccc(OCCO)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C06 compound treatment 8.9873704E7 -6770000.0 -0.35 1.02656509E8 -5920000.0 -0.32 -0.4706 -0.9991 3623052 BCB04_000050 C[C@@]12CCCC(=O)N2CCc3c1[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C07 compound treatment 9.363146E7 -3010000.0 -0.15 9.7127049E7 -1.14E7 -0.62 -0.545 -0.8577 3556309 BCB04_000051 COc1cc2CCN3CCC[C@H]4C(=NO[C@]43c2cc1OC)c5ccc(OCCO)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C08 compound treatment 8.6956497E7 -9690000.0 -0.5 9.9735475E7 -8840000.0 -0.48 -0.6876 -0.9998 3623054 BCB04_000052 CCCC[C@@]12CCCC(=O)N2CCc3c1[nH]c4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C09 compound treatment 8.048422E7 -1.62E7 -0.83 9.0784284E7 -1.78E7 -0.96 -1.263 -0.9974 3623056 BCB04_000053 [N-]=[N+]=NCC(=O)N1CCC2(CC1)N(CNC2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C10 compound treatment 8.0657181E7 -1.6E7 -0.82 9.6666948E7 -1.19E7 -0.64 -1.0327 -0.9926 3623057 BCB04_000054 CCCCCCC1=C[C@@H]2[C@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C11 mock treatment 8.7410038E7 -9230000.0 -0.47 1.05356339E8 -3220000.0 -0.17 -0.4571 -0.9071 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C12 mock treatment 7.8671402E7 -1.8E7 -0.92 9.8473663E7 -1.01E7 -0.54 -1.0359 -0.9684 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C13 compound treatment 8.146469E7 -1.52E7 -0.78 9.9082818E7 -9490000.0 -0.51 -0.9114 -0.9792 3623059 BCB04_000055 CN1CCN(CC1)C(=O)CN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C14 compound treatment 6.7752722E7 -2.89E7 -1.48 8.0284837E7 -2.83E7 -1.52 -2.1242 -0.9999 3623060 BCB04_000056 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C15 mock treatment 8.275389E7 -1.39E7 -0.71 9.4743536E7 -1.38E7 -0.74 -1.03 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C16 mock treatment 8.3370971E7 -1.33E7 -0.68 9.2749679E7 -1.58E7 -0.85 -1.0835 -0.9938 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C17 compound treatment 9.2087971E7 -4550000.0 -0.23 1.0491944E8 -3650000.0 -0.2 -0.3042 -0.9964 3623061 BCB04_000057 [N-]=[N+]=NCC(=O)N1CCN(CC1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C18 compound treatment 6.3280059E7 -3.34E7 -1.71 6.6445113E7 -4.21E7 -2.27 -2.8133 -0.9903 3623062 BCB04_000058 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N([C@@H](C)c3ccccc3)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C19 compound treatment 8.5804369E7 -1.08E7 -0.56 9.7007607E7 -1.16E7 -0.62 -0.8332 -0.9984 3623064 BCB04_000059 [N-]=[N+]=NCC(=O)N1CCOCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C20 compound treatment 7.1447907E7 -2.52E7 -1.29 8.2653467E7 -2.59E7 -1.4 -1.9001 -0.9992 3623065 BCB04_000060 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N([C@@H](C)c3ccccc3)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C21 compound treatment 8.9768511E7 -6870000.0 -0.35 1.02987899E8 -5590000.0 -0.3 -0.4618 -0.9969 3623066 BCB04_000061 COc1ccc(NC(=O)CN=[N+]=[N-])cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C22 compound treatment 8.1842801E7 -1.48E7 -0.76 9.848559E7 -1.01E7 -0.54 -0.9205 -0.9866 3623067 BCB04_000062 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C23 compound treatment 9.5660409E7 -982000.0 -0.05 1.03959948E8 -4610000.0 -0.25 -0.2113 -0.8335 3623069 BCB04_000063 COc1ccc(OC)c(NC(=O)CN=[N+]=[N-])c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 C24 compound treatment 8.9298825E7 -7340000.0 -0.38 8.5414409E7 -2.32E7 -1.25 -1.148 -0.8813 3623070 BCB04_000064 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D01 compound treatment 1.10857949E8 1.42E7 0.73 1.12606413E8 4030000.0 0.22 0.6688 0.8797 3623071 BCB04_000065 CN1C(=O)N[C@H]2[C@@H](COC(=O)c3ccc(cc3)[N+](=O)[O-])[C@]1(C)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D02 compound treatment 9.1720729E7 -4920000.0 -0.25 1.00320455E8 -8250000.0 -0.44 -0.4926 -0.964 3623073 BCB04_000066 CC(C)(C)OC(=O)N[C@H]1CN(CC2=C(COC(=O)c3ccccc3)C[C@]4(Cl)C(Cl)(Cl)[C@]4(Cl)[C@@H]12)S(=O)(=O)c5ccc(Br)cc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D03 compound treatment 9.6914721E7 272000.0 0.01 1.06094051E8 -2480000.0 -0.13 -0.0845 -0.6299 3623074 BCB04_000067 CN1C(=O)N([C@H]2[C@@H](COC(=O)c3ccc(cc3)[N+](=O)[O-])[C@]1(C)Oc4ccccc24)C(=O)CC(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D04 compound treatment 3.7777485E7 -5.89E7 -3.02 3.9057178E7 -6.95E7 -3.74 -4.7804 -0.9943 3623076 BCB04_000068 COc1ccc(CN([C@@H](CO)[C@H]2CO2)S(=O)(=O)c3ccc(Br)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D05 compound treatment 9.2539948E7 -4100000.0 -0.21 1.07718674E8 -854000.0 -0.05 -0.1812 -0.8419 3623078 BCB04_000069 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N=C5SCC(=O)N45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D06 compound treatment 9.7743771E7 1100000.0 0.06 1.02627546E8 -5950000.0 -0.32 -0.1865 -0.5737 3623080 BCB04_000070 COc1ccc(CN([C@H](CN(CCCO[Si](C(C)C)(C(C)C)C(C)C)S(=O)(=O)c2ccc(Br)cc2)[C@H]3CO3)S(=O)(=O)c4ccc(Br)cc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D07 compound treatment 8.2174021E7 -1.45E7 -0.74 9.0686252E7 -1.79E7 -0.96 -1.2055 -0.9917 3623082 BCB04_000071 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccccc5)N=C6SCC(=O)N46)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D08 compound treatment 3.3338961E7 -6.33E7 -3.24 5.17686E7 -5.68E7 -3.06 -4.4572 -0.9996 3623084 BCB04_000072 COc1ccc(CN([C@H](CN(CCCO[Si](C(C)C)(C(C)C)C(C)C)S(=O)(=O)c2ccc(Br)cc2)[C@@H](O)CO)S(=O)(=O)c3ccc(Br)cc3)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D09 compound treatment 8.6386762E7 -1.03E7 -0.53 9.9352526E7 -9220000.0 -0.5 -0.7228 -0.9996 3623086 BCB04_000073 OC[C@@]1(Oc2ccccc2[C@@H]3[C@H]1COC(=O)c4ccccc4)N=C5SCC(=O)N35 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D10 compound treatment 6.6302447E7 -3.03E7 -1.56 7.7504616E7 -3.11E7 -1.67 -2.2826 -0.9993 3623088 BCB04_000074 [O-][N+](=O)c1ccc(cc1)C2Sc3ccccc3C=C2C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D11 mock treatment 8.3858401E7 -1.28E7 -0.66 9.8946068E7 -9630000.0 -0.52 -0.8299 -0.9933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D12 mock treatment 8.8178049E7 -8460000.0 -0.43 1.07604478E8 -969000.0 -0.05 -0.3437 -0.7865 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D13 compound treatment 4.6265368E7 -5.04E7 -2.58 5.2913841E7 -5.57E7 -3.0 -3.9451 -0.9972 3623089 BCB04_000075 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2N(C(=O)c3ccccc3)C(=S)N[C@@]1(C)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D14 compound treatment 3.8628944E7 -5.8E7 -2.97 4.5606709E7 -6.3E7 -3.39 -4.5001 -0.9979 3623091 BCB04_000076 [O-][N+](=O)c1ccc(cc1)C2Oc3ccccc3C=C2C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D15 mock treatment 8.7676249E7 -8970000.0 -0.46 1.07025167E8 -1550000.0 -0.08 -0.3839 -0.8219 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D16 mock treatment 9.6319841E7 -323000.0 -0.02 1.08365418E8 -208000.0 -0.01 -0.0196 -0.9817 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D17 compound treatment 7.7411397E7 -1.92E7 -0.99 8.8563632E7 -2.0E7 -1.08 -1.4589 -0.999 3623092 BCB04_000077 CCOC(=O)OC[C@@H]1[C@@H]2NC(=O)N(C)[C@@]1(COCc3ccc(OC)cc3)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D18 compound treatment 8.0619484E7 -1.6E7 -0.82 8.120317E7 -2.74E7 -1.47 -1.6229 -0.9619 3623094 BCB04_000078 O=CC1=Cc2ccccc2OC1c3ccc(C#N)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D19 compound treatment 6.6302244E7 -3.03E7 -1.56 7.5962213E7 -3.26E7 -1.76 -2.3413 -0.9982 3623095 BCB04_000079 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=O)N2C)[C@@H]4COC(=O)c5ccc(cc5)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D20 compound treatment 9.0634411E7 -6010000.0 -0.31 1.00492508E8 -8080000.0 -0.44 -0.5254 -0.9857 3623097 BCB04_000080 CCOC(=O)C1Nc2cc(OC)c(OC)cc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D21 compound treatment 9.1070587E7 -5570000.0 -0.29 1.02609696E8 -5960000.0 -0.32 -0.429 -0.9983 3623098 BCB04_000081 CCOC(=O)OC[C@@H]1[C@@H]2NC(=O)N(C)[C@@]1(CO)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D22 compound treatment 9.1421797E7 -5220000.0 -0.27 1.00449568E8 -8120000.0 -0.44 -0.4985 -0.9722 3623100 BCB04_000082 CCOC(=O)C1Oc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D23 compound treatment 9.0194596E7 -6450000.0 -0.33 9.8099857E7 -1.05E7 -0.56 -0.6325 -0.9676 3623101 BCB04_000083 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccc(cc5)[N+](=O)[O-])N(C)C(=O)N4C(=O)CC(=O)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 D24 compound treatment 9.4715172E7 -1930000.0 -0.1 1.01017692E8 -7560000.0 -0.41 -0.3576 -0.854 3623103 BCB04_000084 CCOC(=O)C1Oc2ccccc2C=C1/C=N/Nc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E01 mock treatment 1.06224296E8 9580000.0 0.49 1.11024463E8 2450000.0 0.13 0.4406 0.8664 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E02 mock treatment 1.0623901E8 9600000.0 0.49 1.14950412E8 6380000.0 0.34 0.5906 0.9846 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E03 compound treatment 9.8327499E7 1680000.0 0.09 1.08731637E8 159000.0 0.01 0.0671 0.7733 3623105 BCB04_000085 [N-]=[N+]=NCC(=O)Nc1nccs1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E04 compound treatment 6.821628E7 -2.84E7 -1.46 7.6604166E7 -3.2E7 -1.72 -2.2475 -0.9966 3623106 BCB04_000086 CCCCCCC1=C[C@H](C(O)CCCCC)n2n(C1)c(=O)n(c3ccccc3)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E05 compound treatment 8.9935558E7 -6710000.0 -0.34 1.08559326E8 -13700.0 0.0 -0.2436 -0.7086 3623108 BCB04_000087 [N-]=[N+]=NCC(=O)Nc1ccon1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E06 compound treatment 9.8459517E7 1820000.0 0.09 1.12308312E8 3740000.0 0.2 0.2081 0.9387 3623109 BCB04_000088 CCCCCC(O)C1=C[C@@H](C(C)C)n2n(C1)c(=O)n(C)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E07 compound treatment 8.3428935E7 -1.32E7 -0.68 9.7027845E7 -1.15E7 -0.62 -0.9185 -0.9991 3623111 BCB04_000089 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)Nc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E08 compound treatment 8.4440109E7 -1.22E7 -0.63 1.00143453E8 -8430000.0 -0.45 -0.7632 -0.9876 3623113 BCB04_000090 CCCCCCC1=CCn2n([C@H]1C(O)CCCCC)c(=O)n(C)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E09 mock treatment 8.5808908E7 -1.08E7 -0.56 1.02704425E8 -5870000.0 -0.32 -0.6161 -0.9643 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E10 mock treatment 8.2810358E7 -1.38E7 -0.71 1.04470341E8 -4100000.0 -0.22 -0.6575 -0.8855 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E11 compound treatment 8.1475103E7 -1.52E7 -0.78 1.02362867E8 -6210000.0 -0.33 -0.7862 -0.929 3623115 BCB04_000091 [N-]=[N+]=NC[C@@H](Cc1ccccc1)NC(=O)Nc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E12 compound treatment 7.7067273E7 -1.96E7 -1.0 9.722507E7 -1.13E7 -0.61 -1.1416 -0.9717 3623116 BCB04_000092 CCCCCCC1=C[C@H](C(O)CCCCC)n2n(C1)c(=O)n(C)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E13 compound treatment 8.7331044E7 -9310000.0 -0.48 1.08028795E8 -544000.0 -0.03 -0.3582 -0.7491 3189423 BCB04_000093 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E14 compound treatment 8.5289776E7 -1.14E7 -0.58 9.9922766E7 -8650000.0 -0.47 -0.7408 -0.9939 3623067 BCB04_000094 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E15 compound treatment 7.9377424E7 -1.73E7 -0.88 8.4000029E7 -2.46E7 -1.32 -1.5614 -0.9809 3623118 BCB04_000095 CC(C)(C)OC(=O)N/C(=N/C(=O)OC(C)(C)C)/NCCN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E16 compound treatment 6.4572556E7 -3.21E7 -1.64 7.6546271E7 -3.2E7 -1.72 -2.3818 -0.9997 3623070 BCB04_000096 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E17 mock treatment 9.7804572E7 1160000.0 0.06 1.08840779E8 268000.0 0.01 0.0523 0.8537 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E18 mock treatment 9.9262862E7 2620000.0 0.13 1.09518424E8 945000.0 0.05 0.1309 0.9119 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E19 compound treatment 6.3498801E7 -3.31E7 -1.7 7.0185137E7 -3.84E7 -2.07 -2.6629 -0.9952 3623120 BCB04_000097 CC(C)(C)OC(=O)N/C(=N/C(=O)OC(C)(C)C)/NCCCN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E20 compound treatment 9.4991704E7 -1650000.0 -0.08 1.1128857E8 2720000.0 0.15 0.0436 0.2578 3623122 BCB04_000098 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cc(F)cc(Br)c3F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E21 compound treatment 9.6712431E7 69500.0 0.0 1.05643131E8 -2930000.0 -0.16 -0.109 -0.691 3623124 BCB04_000099 [N-]=[N+]=NCCCNC(=O)Nc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E22 compound treatment 1.053701E8 8730000.0 0.45 1.14088328E8 5520000.0 0.3 0.5263 0.9802 3623125 BCB04_000100 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cc(nn3C)c4sc5ccc(Cl)cc5c4C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E23 compound treatment 9.0653094E7 -5990000.0 -0.31 1.07696848E8 -876000.0 -0.05 -0.2504 -0.8063 3623127 BCB04_000101 [N-]=[N+]=NCCNC(=O)Nc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 E24 compound treatment 1.15603179E8 1.9E7 0.97 1.19519002E8 1.09E7 0.59 1.1039 0.9713 3623128 BCB04_000102 CCCCCCC1=C[C@@H]2[C@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F01 mock treatment 1.14194752E8 1.76E7 0.9 1.20398765E8 1.18E7 0.64 1.0864 0.9857 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F02 mock treatment 1.09596773E8 1.3E7 0.66 1.1801641E8 9440000.0 0.51 0.829 0.9913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F03 compound treatment 1.02498124E8 5860000.0 0.3 1.14246117E8 5670000.0 0.31 0.4282 1.0 3623130 BCB04_000103 OC[C@@H]1[C@@H]2N3C(=O)CSC3=N[C@@]1(CO)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F04 compound treatment 9.1702058E7 -4940000.0 -0.25 1.08583759E8 10700.0 0.0 -0.1787 -0.7055 3623132 BCB04_000104 CCOC(=O)C1Oc2ccc(OC)cc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F05 compound treatment 9.5580085E7 -1060000.0 -0.05 1.07225195E8 -1350000.0 -0.07 -0.0898 -0.99 3623133 BCB04_000105 OC[C@@H]1[C@@H]2N3Cc4ccccc4CSC3=N[C@@]1(CO)Oc5ccccc25 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F06 compound treatment 9.1988112E7 -4650000.0 -0.24 1.04245091E8 -4330000.0 -0.23 -0.3335 -0.9999 3623135 BCB04_000106 O=CC1=Cc2ccccc2NC1c3ccc(C#N)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F07 compound treatment 1.00789962E8 4150000.0 0.21 1.12173235E8 3600000.0 0.19 0.2874 0.9989 3623136 BCB04_000107 OC[C@@H]1[C@@H]2N3CCCSC3=N[C@@]1(CO)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F08 compound treatment 8.7378094E7 -9260000.0 -0.47 1.04157357E8 -4420000.0 -0.24 -0.5039 -0.9489 3623138 BCB04_000108 [O-][N+](=O)c1ccc(cc1)C2Sc3ccccc3C=C2/C=N/Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F09 mock treatment 9.471383E7 -1930000.0 -0.1 1.07699785E8 -873000.0 -0.05 -0.1032 -0.9423 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F10 mock treatment 8.7829383E7 -8810000.0 -0.45 1.0592419E8 -2650000.0 -0.14 -0.4203 -0.8872 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F11 compound treatment 7.9002437E7 -1.76E7 -0.9 9.1118843E7 -1.75E7 -0.94 -1.3039 -0.9998 3623140 BCB04_000109 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N=C5Sc6ccc(cc6C(=O)N45)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F12 compound treatment 8.4549242E7 -1.21E7 -0.62 1.00767158E8 -7810000.0 -0.42 -0.7355 -0.9821 3623142 BCB04_000110 COc1cc2NC(C(=Cc2cc1OC)C=O)c3ccc(C#N)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F13 compound treatment 8.5082541E7 -1.16E7 -0.59 1.06503649E8 -2070000.0 -0.11 -0.4978 -0.8256 3623143 BCB04_000111 CC(C)(C)OC(=O)NC(CN(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccc(Br)cc2)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F14 compound treatment 9.0001725E7 -6640000.0 -0.34 1.02447271E8 -6130000.0 -0.33 -0.4739 -0.9999 3623144 BCB04_000112 CCOC(=O)C1Oc2ccc3ccccc3c2C=C1/C=N/Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F15 compound treatment 4.0715946E7 -5.59E7 -2.87 3.8078215E7 -7.05E7 -3.8 -4.7112 -0.9904 3623146 BCB04_000113 CC(C)(C)OC(=O)NCC#CCN(C(COC(=O)c1ccccc1)C=C)S(=O)(=O)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F16 compound treatment 5.1289904E7 -4.54E7 -2.32 6.0282183E7 -4.83E7 -2.6 -3.4825 -0.9984 3623147 BCB04_000114 O=CC1=Cc2ccccc2SC1c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F17 mock treatment 9.3383497E7 -3260000.0 -0.17 1.07814845E8 -758000.0 -0.04 -0.147 -0.8548 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F18 mock treatment 9.8882126E7 2240000.0 0.11 1.09378726E8 806000.0 0.04 0.1118 0.9115 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F19 compound treatment 8.6006626E7 -1.06E7 -0.55 9.6914895E7 -1.17E7 -0.63 -0.8294 -0.9975 3623148 BCB04_000115 CC(C)(C)OC(=O)NCC#CCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F20 compound treatment 9.7245542E7 603000.0 0.03 1.0663692E8 -1940000.0 -0.1 -0.0519 -0.4771 3623149 BCB04_000116 CCCCC1Nc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F21 compound treatment 9.8701679E7 2060000.0 0.11 1.05674263E8 -2900000.0 -0.16 -0.0358 -0.1898 3623150 BCB04_000117 CC(C)(C)OC(=O)N(CC#CCO)S(=O)(=O)c1ccccc1[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F22 compound treatment 9.8482353E7 1840000.0 0.09 1.06815498E8 -1760000.0 -0.09 -3.0E-4 -0.002 3623151 BCB04_000118 O=CC1=Cc2ccccc2OC1c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F23 compound treatment 9.5731733E7 -911000.0 -0.05 1.07379818E8 -1190000.0 -0.06 -0.0785 -0.9877 3623152 BCB04_000119 Brc1ccc(cc1)S(=O)(=O)NCC#CCOC(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 F24 compound treatment 1.12735958E8 1.61E7 0.82 1.22925772E8 1.44E7 0.77 1.1298 0.9995 3623153 BCB04_000120 CCCCC1Sc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G01 compound treatment 1.06803587E8 1.02E7 0.52 1.05451717E8 -3120000.0 -0.17 0.2494 0.4557 3623154 BCB04_000121 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G02 compound treatment 1.1209387E8 1.55E7 0.79 1.23090157E8 1.45E7 0.78 1.1127 1.0 3623156 BCB04_000122 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G03 mock treatment 1.03511118E8 6870000.0 0.35 1.17272315E8 8700000.0 0.47 0.5802 0.9901 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G04 mock treatment 1.02154939E8 5510000.0 0.28 1.17394362E8 8820000.0 0.48 0.5357 0.9692 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G05 compound treatment 1.03052168E8 6410000.0 0.33 1.15279097E8 6710000.0 0.36 0.4876 0.9989 3623157 BCB04_000123 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G06 compound treatment 8.8298313E7 -8340000.0 -0.43 9.4927675E7 -1.36E7 -0.73 -0.822 -0.9668 3623159 BCB04_000124 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cc(F)ccc3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G07 compound treatment 9.603854E7 -604000.0 -0.03 1.09333682E8 761000.0 0.04 0.0071 0.1375 3623161 BCB04_000125 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G08 compound treatment 1.00043579E8 3400000.0 0.17 1.1266174E8 4090000.0 0.22 0.2789 0.9933 3623163 BCB04_000126 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cc(F)ccc3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G09 compound treatment 9.3175477E7 -3470000.0 -0.18 1.06054872E8 -2520000.0 -0.14 -0.2216 -0.9911 3623164 BCB04_000127 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2CN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G10 compound treatment 9.5647733E7 -995000.0 -0.05 1.09586397E8 1010000.0 0.05 0.0025 0.0337 3623166 BCB04_000128 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cc(Cl)ccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G11 compound treatment 2.7348616E7 -6.93E7 -3.55 2.7931229E7 -8.06E7 -4.34 -5.582 -0.995 3623168 BCB04_000129 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G12 compound treatment 8.001224E7 -1.66E7 -0.85 8.9024554E7 -1.95E7 -1.05 -1.3471 -0.9945 3623116 BCB04_000130 CCCCCCC1=C[C@H](C(O)CCCCC)n2n(C1)c(=O)n(C)c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G13 compound treatment 5.5163569E7 -4.15E7 -2.13 7.0696922E7 -3.79E7 -2.04 -2.9455 -0.9998 3623170 BCB04_000131 COC(=O)[C@@H](NC(=O)CN=[N+]=[N-])c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G14 compound treatment 2.6234924E7 -7.04E7 -3.61 2.6917713E7 -8.17E7 -4.4 -5.661 -0.9952 3623172 BCB04_000132 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G15 compound treatment 2.6423253E7 -7.02E7 -3.6 2.7036691E7 -8.15E7 -4.39 -5.6496 -0.9951 3623174 BCB04_000133 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN=[N+]=[N-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G16 compound treatment 3.9814758E7 -5.68E7 -2.91 5.3292042E7 -5.53E7 -2.98 -4.1645 -0.9999 3623176 BCB04_000134 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(Cl)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G17 compound treatment 8.8987756E7 -7660000.0 -0.39 1.01625157E8 -6950000.0 -0.37 -0.542 -0.9997 3623178 BCB04_000135 COC(=O)[C@H](O)[C@H](N=[N+]=[N-])c1ccc(OC)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G18 compound treatment 2.7361762E7 -6.93E7 -3.55 2.9886013E7 -7.87E7 -4.24 -5.5071 -0.9961 3623180 BCB04_000136 CCCCCCC1=C[C@H](C(O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G19 mock treatment 9.6586643E7 -56300.0 0.0 1.11097134E8 2520000.0 0.14 0.0941 0.692 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G20 mock treatment 1.01062689E8 4420000.0 0.23 1.12239783E8 3670000.0 0.2 0.2998 0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G21 compound treatment 1.02913396E8 6270000.0 0.32 1.11259668E8 2690000.0 0.14 0.3296 0.935 3623182 BCB04_000137 COC(=O)c1cn(CC(=O)Nc2nc3ccccc3s2)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G22 compound treatment 1.03203472E8 6560000.0 0.34 1.0797804E8 -595000.0 -0.03 0.2151 0.6368 3623183 BCB04_000138 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G23 compound treatment 9.8405061E7 1760000.0 0.09 1.08902252E8 329000.0 0.02 0.0764 0.8301 3623185 BCB04_000139 O=C1COC[C@H](N1CC#C)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 G24 compound treatment 1.13442385E8 1.68E7 0.86 1.19833516E8 1.13E7 0.61 1.0376 0.9853 3623187 BCB04_000140 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc(Cl)c3Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H01 compound treatment 9.8436211E7 1790000.0 0.09 1.01737933E8 -6840000.0 -0.37 -0.1953 -0.5147 3623189 BCB04_000141 CC(C)(C)OC(=O)N(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccccc2[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H02 compound treatment 9.8202911E7 1560000.0 0.08 1.03433766E8 -5140000.0 -0.28 -0.1392 -0.4831 3623190 BCB04_000142 CCOC(=O)C1Oc2cccc(C)c2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H03 mock treatment 1.06953431E8 1.03E7 0.53 1.17006388E8 8430000.0 0.45 0.6948 0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H04 mock treatment 9.9550395E7 2910000.0 0.15 1.09558842E8 986000.0 0.05 0.1429 0.9034 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H05 compound treatment 9.6074321E7 -569000.0 -0.03 1.08879284E8 306000.0 0.02 -0.0089 -0.2671 3623191 BCB04_000143 Brc1ccc(cc1)S(=O)(=O)NC(COC(=O)c2ccccc2)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H06 compound treatment 9.9231072E7 2590000.0 0.13 1.11147664E8 2570000.0 0.14 0.1918 0.9998 3623192 BCB04_000144 CCOC(=O)C1Nc2cc3OCOc3cc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H07 compound treatment 8.9588396E7 -7050000.0 -0.36 1.05362315E8 -3210000.0 -0.17 -0.3779 -0.943 3623193 BCB04_000145 CC(C)(C)OC(=O)N(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H08 compound treatment 8.2177158E7 -1.45E7 -0.74 9.5737078E7 -1.28E7 -0.69 -1.013 -0.9994 3623194 BCB04_000146 CCCC1Oc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H09 compound treatment 9.2420748E7 -4220000.0 -0.22 1.074105E8 -1160000.0 -0.06 -0.1973 -0.8758 3623195 BCB04_000147 CC(C)(C)OC(=O)NS(=O)(=O)c1ccc(Br)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H10 compound treatment 8.6220537E7 -1.04E7 -0.53 9.7885737E7 -1.07E7 -0.58 -0.7847 -0.9993 3623196 BCB04_000148 CCCC1Sc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H11 compound treatment 7.4071453E7 -2.26E7 -1.16 8.7689966E7 -2.09E7 -1.12 -1.6132 -0.9999 3623197 BCB04_000149 CC(C)(C)OC(=O)NC(CN(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccccc2[N+](=O)[O-])C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H12 compound treatment 8.3801397E7 -1.28E7 -0.66 1.03791174E8 -4780000.0 -0.26 -0.6475 -0.9161 3623198 BCB04_000150 CCCCC1Oc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H13 compound treatment 5.6930796E7 -3.97E7 -2.04 7.7877863E7 -3.07E7 -1.65 -2.608 -0.9947 3623199 BCB04_000151 CC(C)(C)OC(=O)NCC#CCN(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H14 compound treatment 4.9866901E7 -4.68E7 -2.4 5.6104023E7 -5.25E7 -2.83 -3.6931 -0.9967 3623200 BCB04_000152 CCOC(=O)C1Oc2cc(OC)ccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H15 compound treatment 9.0870598E7 -5770000.0 -0.3 1.03739796E8 -4830000.0 -0.26 -0.3932 -0.998 3623201 BCB04_000153 CC(C)(C)OC(=O)N(CC#CCN(C(COC(=O)c1ccccc1)C=C)S(=O)(=O)c2ccc(Br)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H16 compound treatment 8.2996572E7 -1.36E7 -0.7 9.4019392E7 -1.46E7 -0.78 -1.0487 -0.9984 3623202 BCB04_000154 CCOC(=O)C1Oc2c(OC)cccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H17 compound treatment 9.4311703E7 -2330000.0 -0.12 1.05607146E8 -2970000.0 -0.16 -0.1974 -0.9898 3623203 BCB04_000155 CC(C)(C)OC(=O)NC1CN(CC(=C1)C(=C)COC(=O)c2ccccc2)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H18 compound treatment 9.0885997E7 -5760000.0 -0.3 1.01798578E8 -6770000.0 -0.36 -0.4666 -0.9945 3623204 BCB04_000156 CCOC(=O)C1Sc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H19 mock treatment 1.00504157E8 3860000.0 0.2 1.12598372E8 4030000.0 0.22 0.2932 0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H20 mock treatment 9.7832816E7 1190000.0 0.06 1.08508399E8 -64600.0 0.0 0.0407 0.6657 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H21 compound treatment 9.5805898E7 -837000.0 -0.04 1.09001029E8 428000.0 0.02 -0.014 -0.2882 3623205 BCB04_000157 CC(C)(C)OC(=O)NCC#CCN(CC#CCN([C@H](COC(=O)c1ccccc1)C=C)S(=O)(=O)c2ccc(Br)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H22 compound treatment 8.8677488E7 -7970000.0 -0.41 9.5627079E7 -1.29E7 -0.7 -0.7816 -0.9675 3623207 BCB04_000158 O=CC1=Cc2ccccc2OC1c3ccc4ccccc4c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H23 compound treatment 1.067502E8 1.01E7 0.52 1.16794486E8 8220000.0 0.44 0.6794 0.9969 3623208 BCB04_000159 CC(C)(C)OC(=O)N(CC#CCN(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccc(Br)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 H24 compound treatment 1.04156325E8 7510000.0 0.39 1.18810451E8 1.02E7 0.55 0.6621 0.9846 3623209 BCB04_000160 [O-][N+](=O)c1ccc(cc1)C2Oc3ccccc3C=C2/C=N/Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I01 compound treatment 1.04281862E8 7640000.0 0.39 1.12319724E8 3750000.0 0.2 0.4195 0.9525 3623211 BCB04_000161 O=C(Cn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)N4CCC5(CC4)N(CNC5=O)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I02 compound treatment 1.0630582E8 9660000.0 0.5 1.19169904E8 1.06E7 0.57 0.7537 0.9975 3623213 BCB04_000162 CCCCCCC1=C[C@@H]2[C@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc(Cl)c3Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I03 compound treatment 1.07878958E8 1.12E7 0.58 1.18202968E8 9630000.0 0.52 0.7739 0.9986 3623214 BCB04_000163 CN1CCN(CC1)C(=O)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I04 compound treatment 6.1771964E7 -3.49E7 -1.79 6.0660671E7 -4.79E7 -2.58 -3.0882 -0.9839 3623216 BCB04_000164 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(Br)c(Cl)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I05 mock treatment 9.7734665E7 1090000.0 0.06 1.10689412E8 2120000.0 0.11 0.1202 0.9464 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I06 mock treatment 9.8034265E7 1390000.0 0.07 1.11470532E8 2900000.0 0.16 0.1608 0.937 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I07 compound treatment 9.9027618E7 2380000.0 0.12 1.09530772E8 958000.0 0.05 0.1229 0.9264 3623218 BCB04_000165 O=C(Cn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)N4CCN(CC4)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I08 compound treatment 9.1184536E7 -5460000.0 -0.28 1.05758193E8 -2810000.0 -0.15 -0.305 -0.9586 3623220 BCB04_000166 CCCCCCC1=C[C@@H]2[C@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(Br)c(Cl)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I09 compound treatment 8.1821118E7 -1.48E7 -0.76 1.01161461E8 -7410000.0 -0.4 -0.8194 -0.9549 3623221 BCB04_000167 O=C(Cn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)N4CCOCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I10 compound treatment 8.6031643E7 -1.06E7 -0.54 1.06076189E8 -2500000.0 -0.13 -0.4796 -0.8561 3623223 BCB04_000168 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc(Cl)n3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I11 compound treatment 9.0547374E7 -6100000.0 -0.31 1.09845698E8 1270000.0 0.07 -0.1724 -0.5392 3623225 BCB04_000169 COc1ccc(NC(=O)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2)cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I12 compound treatment 8.8531344E7 -8110000.0 -0.42 1.06419159E8 -2150000.0 -0.12 -0.376 -0.8711 3623227 BCB04_000170 CCCCCCC1=C[C@@H]2[C@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc(Cl)n3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I13 compound treatment 8.7686473E7 -8960000.0 -0.46 1.05484159E8 -3090000.0 -0.17 -0.4422 -0.9057 3623228 BCB04_000171 COc1ccc(OC)c(NC(=O)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I14 compound treatment 8.8932505E7 -7710000.0 -0.4 1.01828169E8 -6740000.0 -0.36 -0.5363 -0.9991 2108247 BCB04_000172 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I15 compound treatment 9.4887868E7 -1760000.0 -0.09 1.08422038E8 -151000.0 -0.01 -0.0694 -0.7679 3623230 BCB04_000173 O=C(Cn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)Nc4nccs4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I16 compound treatment 9.0869732E7 -5770000.0 -0.3 1.0406165E8 -4510000.0 -0.24 -0.381 -0.9952 3623232 BCB04_000174 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N(CC=C)[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I17 compound treatment 9.5640257E7 -1000000.0 -0.05 1.08466377E8 -107000.0 -0.01 -0.0404 -0.7813 3623234 BCB04_000175 O=C(Cn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)Nc4ccon4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I18 compound treatment 6.8526663E7 -2.81E7 -1.44 7.9317077E7 -2.93E7 -1.58 -2.133 -0.999 3623236 BCB04_000176 CCOC(=O)[C@@H]1[C@@H]2NC(=S)N[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I19 compound treatment 1.04282441E8 7640000.0 0.39 1.12647022E8 4070000.0 0.22 0.432 0.9625 3623237 BCB04_000177 O=C(N[C@@H](Cc1ccccc1)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2)Nc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I20 compound treatment 1.00383257E8 3740000.0 0.19 1.12323217E8 3750000.0 0.2 0.2784 0.9997 3623239 BCB04_000178 CCOC(=O)[C@@H]1[C@@H]2NC(=S)N(CC=C)[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I21 mock treatment 9.7469697E7 827000.0 0.04 1.08661758E8 88700.0 0.0 0.0333 0.7819 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I22 mock treatment 9.6627876E7 -15000.0 0.0 1.10129131E8 1560000.0 0.08 0.0587 0.7006 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I23 compound treatment 1.02363332E8 5720000.0 0.29 1.13546088E8 4970000.0 0.27 0.3967 0.999 3623241 BCB04_000179 O=C(N[C@H](Cc1ccccc1)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2)Nc5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 I24 compound treatment 1.05950919E8 9310000.0 0.48 1.21516098E8 1.29E7 0.7 0.8302 0.9829 3623242 BCB04_000180 C[C@]1(Oc2ccccc2[C@H]3NC(=S)N1CC=C)[C@@H]3CO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J01 compound treatment 4.868402E7 -4.8E7 -2.46 5.5763211E7 -5.28E7 -2.84 -3.749 -0.9974 3623244 BCB04_000181 CC(C)(C)OC(=O)NCC#CCOC(=O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J02 compound treatment 1.01578111E8 4940000.0 0.25 1.14477448E8 5900000.0 0.32 0.4037 0.9936 3623245 BCB04_000182 N#Cc1ccc(cc1)C2Oc3ccccc3C=C2/C=N/Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J03 compound treatment 1.03330642E8 6690000.0 0.34 1.14599673E8 6030000.0 0.32 0.4719 0.9996 3623247 BCB04_000183 CC(C)(C)OC(=O)NC(COC(=O)c1ccccc1)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J04 compound treatment 2.5816027E7 -7.08E7 -3.63 2.6685159E7 -8.19E7 -4.41 -5.685 -0.9953 3623248 BCB04_000184 Clc1ccc(cc1)C2Nc3ccccc3C=C2C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J05 mock treatment 1.01488534E8 4850000.0 0.25 1.13515555E8 4940000.0 0.27 0.3638 0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J06 mock treatment 9.8051428E7 1410000.0 0.07 1.13655782E8 5080000.0 0.27 0.2446 0.8641 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J07 compound treatment 8.9234492E7 -7410000.0 -0.38 1.01826317E8 -6750000.0 -0.36 -0.5254 -0.9998 3623249 BCB04_000185 CC(C)(C)OC(=O)N[C@@H](CN(CC#CCN([C@H](COC(=O)c1ccccc1)C=C)S(=O)(=O)c2ccc(Br)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J08 compound treatment 9.3593159E7 -3050000.0 -0.16 1.09962861E8 1390000.0 0.07 -0.0576 -0.3324 3623251 BCB04_000186 Clc1ccc(cc1)C2Nc3ccccc3C=C2/C=N/Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J09 compound treatment 9.5471906E7 -1170000.0 -0.06 1.07038827E8 -1530000.0 -0.08 -0.1009 -0.9877 3623253 BCB04_000187 CC(C)(C)OC(=O)NC(CN(CC#CCN(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccc(Br)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J10 compound treatment 3.6619054E7 -6.0E7 -3.08 5.0775832E7 -5.78E7 -3.11 -4.3761 -1.0 3623254 BCB04_000188 CCOC(=O)C1Nc2cc(F)ccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J11 compound treatment 8.9390734E7 -7250000.0 -0.37 1.03568607E8 -5000000.0 -0.27 -0.4534 -0.9875 3623255 BCB04_000189 [O-][N+](=O)c1ccccc1S(=O)(=O)NCC#CCN(CC#CCOC(=O)c2ccccc2)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J12 compound treatment 8.5031068E7 -1.16E7 -0.6 9.8235403E7 -1.03E7 -0.56 -0.8145 -0.9994 3623256 BCB04_000190 O=CC1=Cc2ccccc2SC1c3ccc(C#N)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J13 compound treatment 8.4099306E7 -1.25E7 -0.64 1.00062753E8 -8510000.0 -0.46 -0.7787 -0.9862 3623257 BCB04_000191 CC(C)(C)OC(=O)N[C@H](CN(CC#CCN([C@H](COC(=O)c1ccccc1)C=C)S(=O)(=O)c2ccc(Br)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J14 compound treatment 5.2405227E7 -4.42E7 -2.27 7.0680214E7 -3.79E7 -2.04 -3.0461 -0.9986 3623258 BCB04_000192 Brc1ccc(cc1)C2Oc3ccccc3C=C2C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J15 compound treatment 7.664616E7 -2.0E7 -1.02 8.2910988E7 -2.57E7 -1.38 -1.7019 -0.9892 3623259 BCB04_000193 CC(C)(C)OC(=O)N[C@H](CN([C@H](COC(=O)c1ccccc1)C=C)S(=O)(=O)c2ccc(Br)cc2)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J16 compound treatment 7.7495482E7 -1.91E7 -0.98 8.7571476E7 -2.1E7 -1.13 -1.4936 -0.9975 3623261 BCB04_000194 CCOC(=O)C1Oc2ccc(OC)cc2C=C1/C=N/Nc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J17 compound treatment 3.8267088E7 -5.84E7 -2.99 4.2557524E7 -6.6E7 -3.55 -4.6294 -0.9963 3623263 BCB04_000195 CC(C)(C)OC(=O)N[C@@H]1CN([C@H](COC(=O)c2ccccc2)C=C1)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J18 compound treatment 9.3971298E7 -2670000.0 -0.14 1.02741954E8 -5830000.0 -0.31 -0.3189 -0.9308 3623265 BCB04_000196 CCOC(=O)C1Nc2cc(Cl)ccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J19 compound treatment 8.8443904E7 -8200000.0 -0.42 1.01864457E8 -6710000.0 -0.36 -0.5526 -0.9972 3623266 BCB04_000197 CC(C)(C)OC(=O)N[C@H]1CN(CC(=C1)C2=C[C@@H](COC(=O)c3ccccc3)N(C2)S(=O)(=O)c4ccc(Br)cc4)S(=O)(=O)c5ccccc5[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J20 compound treatment 8.1489329E7 -1.52E7 -0.78 9.2475227E7 -1.61E7 -0.87 -1.1622 -0.9985 3623268 BCB04_000198 CCOC(=O)C1Oc2c(F)cccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J21 mock treatment 9.6150535E7 -492000.0 -0.03 1.07958133E8 -615000.0 -0.03 -0.0413 -0.991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J22 mock treatment 1.00803222E8 4160000.0 0.21 1.08130233E8 -443000.0 -0.02 0.1339 0.6241 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J23 compound treatment 9.3220881E7 -3420000.0 -0.18 9.931974E7 -9250000.0 -0.5 -0.4764 -0.9018 3623269 BCB04_000199 CC(C)(C)OC(=O)N[C@@H]1CN(CC(=C1)C2=C[C@@H](COC(=O)c3ccccc3)N(C2)S(=O)(=O)c4ccc(Br)cc4)S(=O)(=O)c5ccccc5[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 J24 compound treatment 1.08106064E8 1.15E7 0.59 1.15819511E8 7250000.0 0.39 0.6914 0.9802 3623270 BCB04_000200 CCCC1Nc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K01 compound treatment 1.11008496E8 1.44E7 0.74 1.31583486E8 2.3E7 1.24 1.3968 0.9691 3623271 BCB04_000201 O=C(N[C@@H](Cc1ccccc1)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K02 compound treatment 9.2814768E7 -3830000.0 -0.2 1.26106506E8 1.75E7 0.94 0.5289 0.5485 3623273 BCB04_000202 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N[C@@]1(COCc3ccc(OC)cc3)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K03 compound treatment 1.02854486E8 6210000.0 0.32 1.30235757E8 2.17E7 1.17 1.05 0.8683 3623275 BCB04_000203 O=C(NCCCn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K04 compound treatment 9.286663E7 -3780000.0 -0.19 1.12929316E8 4360000.0 0.23 0.029 0.0954 3623277 BCB04_000204 CCOC(=O)[C@@H]1[C@@H]2NC(=S)N[C@@]1(COCc3ccc(OC)cc3)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K05 compound treatment 9.8924371E7 2280000.0 0.12 1.16544076E8 7970000.0 0.43 0.3862 0.8681 3623279 BCB04_000205 O=C(NCCn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K06 compound treatment 8.7807183E7 -8840000.0 -0.45 1.04789792E8 -3780000.0 -0.2 -0.4643 -0.935 3623281 BCB04_000206 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=O)N2CC=C)[C@@H]4CO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K07 mock treatment 9.7166835E7 524000.0 0.03 1.10951115E8 2380000.0 0.13 0.1095 0.8372 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K08 mock treatment 9.0496116E7 -6150000.0 -0.32 1.07608171E8 -965000.0 -0.05 -0.2595 -0.8127 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K09 compound treatment 9.4336144E7 -2310000.0 -0.12 1.08063128E8 -510000.0 -0.03 -0.103 -0.8487 3623283 BCB04_000207 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(CN4[C@@H](COCC4=O)c5ccccc5)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K10 compound treatment 8.8038059E7 -8600000.0 -0.44 1.08226064E8 -347000.0 -0.02 -0.3251 -0.7364 3623285 BCB04_000208 COc1ccc(COC[C@]2(NC(=O)N[C@H]3[C@H]2CO)Oc4ccccc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K11 compound treatment 9.4722307E7 -1920000.0 -0.1 1.11990701E8 3420000.0 0.18 0.0605 0.29 3623287 BCB04_000209 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(CN4[C@@H](COCC4=O)c5ccccc5)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K12 compound treatment 9.0082654E7 -6560000.0 -0.34 1.05112119E8 -3460000.0 -0.19 -0.3695 -0.9613 3623289 BCB04_000210 C[C@]1(NC(=S)N[C@H]2[C@H]1CO)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K13 compound treatment 9.1602114E7 -5040000.0 -0.26 1.06234004E8 -2340000.0 -0.13 -0.2718 -0.9455 3623291 BCB04_000211 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K14 compound treatment 7.0475222E7 -2.62E7 -1.34 8.5066896E7 -2.35E7 -1.27 -1.8434 -0.9996 3623293 BCB04_000212 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2NC(=S)N[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K15 mock treatment 9.115805E7 -5480000.0 -0.28 1.04998209E8 -3570000.0 -0.19 -0.3349 -0.9829 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K16 mock treatment 9.1845702E7 -4800000.0 -0.25 1.06000508E8 -2570000.0 -0.14 -0.2718 -0.9632 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K17 compound treatment 9.7640435E7 998000.0 0.05 1.11009987E8 2440000.0 0.13 0.1289 0.9156 3623295 BCB04_000213 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(CN4[C@@H](COCC4=O)c5ccccc5)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K18 compound treatment 9.007829E7 -6560000.0 -0.34 9.976402E7 -8810000.0 -0.47 -0.5733 -0.9858 3623297 BCB04_000214 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2N3Cc4ccccc4CSC3=N[C@@]1(C)Oc5ccccc25 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K19 compound treatment 5.8007547E7 -3.86E7 -1.98 8.0733551E7 -2.78E7 -1.5 -2.4603 -0.9906 3623299 BCB04_000215 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K20 compound treatment 9.5742444E7 -900000.0 -0.05 1.07134395E8 -1440000.0 -0.08 -0.0874 -0.9694 3623301 BCB04_000216 COc1ccc(COC[C@]2(NC(=S)N[C@H]3[C@H]2CO)Oc4ccccc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K21 compound treatment 9.1283948E7 -5360000.0 -0.27 1.01002348E8 -7570000.0 -0.41 -0.4825 -0.9815 3623303 BCB04_000217 COC(=O)[C@@H](NC(=O)Cn1cc(CN2[C@@H](COCC2=O)c3ccccc3)nn1)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K22 compound treatment 9.7814679E7 1170000.0 0.06 1.0591836E8 -2650000.0 -0.14 -0.0586 -0.378 3623305 BCB04_000218 C[C@]1(NC(=O)N[C@H]2[C@H]1CO)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K23 mock treatment 9.8635086E7 1990000.0 0.1 1.08512901E8 -60100.0 0.0 0.0699 0.6843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 K24 mock treatment 1.06187685E8 9540000.0 0.49 1.18465637E8 9890000.0 0.53 0.7226 0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L01 compound treatment 9.9064164E7 2420000.0 0.12 1.19271448E8 1.07E7 0.58 0.4951 0.8401 3616022 BCB04_000219 CC(C)(C)OC(=O)NC(CO)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L02 compound treatment 7.2732766E7 -2.39E7 -1.23 1.04905295E8 -3670000.0 -0.2 -1.0062 -0.8106 3623307 BCB04_000220 CCOC(=O)C1Nc2ccccc2C=C1C=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L03 compound treatment 8.334305E7 -1.33E7 -0.68 1.0288977E8 -5680000.0 -0.31 -0.6984 -0.9347 3623308 BCB04_000221 [O-][N+](=O)c1ccccc1S(=O)(=O)NCC#CCN(C(COC(=O)c2ccccc2)C=C)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L04 compound treatment 2.5551973E7 -7.11E7 -3.64 2.6163101E7 -8.24E7 -4.44 -5.7144 -0.9952 3623309 BCB04_000222 CC(CN1CCCC1)C(=O)c2ccc(cc2)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L05 compound treatment 8.7407476E7 -9240000.0 -0.47 9.7266143E7 -1.13E7 -0.61 -0.7652 -0.9922 3623310 BCB04_000223 CC(C)(C)OC(=O)NCC(=C)C1=CC(COC(=O)c2ccccc2)N(C1)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L06 compound treatment 8.9209601E7 -7430000.0 -0.38 1.02389003E8 -6180000.0 -0.33 -0.5049 -0.9978 3623311 BCB04_000224 Cc1ccccc1n2c(Cn3cnc4c(N)ncnc34)nc5cccc(C)c5c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L07 mock treatment 9.6637906E7 -5000.0 0.0 1.11455765E8 2880000.0 0.16 0.1096 0.7059 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L08 mock treatment 9.0129981E7 -6510000.0 -0.33 1.06317376E8 -2260000.0 -0.12 -0.3219 -0.9063 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L09 compound treatment 2.7771802E7 -6.89E7 -3.53 2.9571093E7 -7.9E7 -4.25 -5.5042 -0.9957 3623312 BCB04_000225 CC(C)(C)OC(=O)N[C@H]1CN(CC2=C(COC(=O)c3ccccc3)C[C@H]4[C@@H]([C@H]12)C(=O)c5ccccc5C4=O)S(=O)(=O)c6ccc(Br)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L10 compound treatment 8.8160556E7 -8480000.0 -0.43 1.00916049E8 -7660000.0 -0.41 -0.599 -0.9997 3623314 BCB04_000226 Cc1ccccc1Oc2cccc3c(=O)cc([nH]c23)N4CCOCC4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L11 compound treatment 6.8550951E7 -2.81E7 -1.44 9.5027623E7 -1.35E7 -0.73 -1.5339 -0.9503 3623315 BCB04_000227 CC(C)(C)OC(=O)NC1CC=C(CN(C1)S(=O)(=O)c2ccc(Br)cc2)C(=C)COC(=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L12 mock treatment 9.3344444E7 -3300000.0 -0.17 1.06107204E8 -2470000.0 -0.13 -0.2134 -0.9929 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L13 compound treatment 7.8158166E7 -1.85E7 -0.95 1.00532489E8 -8040000.0 -0.43 -0.9761 -0.9371 3623316 BCB04_000228 CC(C)(C)OC(=O)NC(CC=C)CN(CC#CCOC(=O)c1ccccc1)S(=O)(=O)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L14 mock treatment 9.833702E7 1690000.0 0.09 1.05338268E8 -3230000.0 -0.17 -0.0618 -0.3174 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L15 mock treatment 8.8472517E7 -8170000.0 -0.42 1.05926153E8 -2650000.0 -0.14 -0.3969 -0.8972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L16 mock treatment 8.7672106E7 -8970000.0 -0.46 1.03233634E8 -5340000.0 -0.29 -0.5284 -0.9745 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L17 compound treatment 2.6720816E7 -6.99E7 -3.58 2.7705636E7 -8.09E7 -4.35 -5.6133 -0.9953 3623317 BCB04_000229 CC(C)(C)OC(=O)N[C@H]1CN(CC2=C(COC(=O)c3ccccc3)C[C@@H]4[C@H]([C@@H]12)C(=O)c5ccccc5C4=O)S(=O)(=O)c6ccc(Br)cc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L18 mock treatment 9.2492109E7 -4150000.0 -0.21 1.07629432E8 -944000.0 -0.05 -0.1864 -0.852 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L19 compound treatment 9.1023638E7 -5620000.0 -0.29 1.05452443E8 -3120000.0 -0.17 -0.3225 -0.9671 3623318 BCB04_000230 CC(C)(C)OC(=O)NCC1=CC(COC(=O)c2ccccc2)N(CC1=C)S(=O)(=O)c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L20 mock treatment 1.03779537E8 7140000.0 0.37 1.14840389E8 6270000.0 0.34 0.4973 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L21 compound treatment 9.1671979E7 -4970000.0 -0.25 1.03494376E8 -5080000.0 -0.27 -0.3735 -0.9994 3623319 BCB04_000231 COc1ccc(CN(C2=CCC3(C#N)C(=O)C=CC(=O)C3(C2)C=N)S(=O)(=O)c4ccc(Br)cc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L22 mock treatment 9.5398985E7 -1240000.0 -0.06 1.06399935E8 -2170000.0 -0.12 -0.1278 -0.9592 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L23 mock treatment 9.6433984E7 -209000.0 -0.01 1.07408558E8 -1160000.0 -0.06 -0.0519 -0.816 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 L24 mock treatment 1.10041366E8 1.34E7 0.69 1.18780754E8 1.02E7 0.55 0.8743 0.9939 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M01 compound treatment 9.1327089E7 -5320000.0 -0.27 1.08469809E8 -103000.0 -0.01 -0.1966 -0.7214 3623320 BCB04_000232 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(CN4[C@@H](COCC4=O)c5ccccc5)nn3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M02 compound treatment 1.00256744E8 3610000.0 0.19 1.12424333E8 3850000.0 0.21 0.2776 0.9984 3623322 BCB04_000233 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2NC(=O)N[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M03 compound treatment 1.05585609E8 8940000.0 0.46 1.18525824E8 9950000.0 0.54 0.7031 0.997 3623324 BCB04_000234 COC(=O)[C@@H](O)[C@H](c1ccc(OC)cc1)n2cc(CN3[C@@H](COCC3=O)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M04 compound treatment 1.03753528E8 7110000.0 0.36 1.172922E8 8720000.0 0.47 0.5897 0.9922 3623326 BCB04_000235 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N(C)[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M05 compound treatment 1.00456938E8 3810000.0 0.2 1.11629544E8 3060000.0 0.16 0.2546 0.9963 3623328 BCB04_000236 COc1ccc(C#C)cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M06 compound treatment 9.725207E7 609000.0 0.03 1.12331344E8 3760000.0 0.2 0.1652 0.8066 3623329 BCB04_000237 C[C@@]1(Oc2ccccc2[C@@H]3[C@H]1CO)N=C4SCc5ccccc5CN34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M07 compound treatment 9.0495305E7 -6150000.0 -0.32 9.7486568E7 -1.11E7 -0.6 -0.645 -0.9554 3623331 BCB04_000238 COc1ccc(cc1OC)c2cn(CC(=O)N3CCC4(CC3)N(CNC4=O)c5ccccc5)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M08 compound treatment 9.3893067E7 -2750000.0 -0.14 1.04815092E8 -3760000.0 -0.2 -0.2428 -0.9844 3623332 BCB04_000239 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N(C)[C@@]1(COCc3ccc(OC)cc3)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M09 mock treatment 9.6806391E7 163000.0 0.01 1.08798038E8 225000.0 0.01 0.0145 0.9838 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M10 mock treatment 8.8803349E7 -7840000.0 -0.4 1.05130501E8 -3440000.0 -0.19 -0.4152 -0.9383 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M11 compound treatment 8.5425777E7 -1.12E7 -0.57 1.04530349E8 -4040000.0 -0.22 -0.5605 -0.9117 3623334 BCB04_000240 COc1ccc(cc1OC)c2cn(CC(=O)N3CCN(C)CC3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M12 compound treatment 9.1637685E7 -5010000.0 -0.26 1.05428993E8 -3140000.0 -0.17 -0.3011 -0.9797 3623335 BCB04_000241 CC(C)(C)[Si](C)(C)OC[C@@H]1[C@@H]2N3C(=O)CSC3=N[C@@]1(C)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M13 mock treatment 8.8120693E7 -8520000.0 -0.44 1.04838937E8 -3730000.0 -0.2 -0.451 -0.938 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M14 mock treatment 8.7413759E7 -9230000.0 -0.47 1.0623013E8 -2340000.0 -0.13 -0.4237 -0.8655 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M15 compound treatment 8.3053553E7 -1.36E7 -0.7 1.03177417E8 -5400000.0 -0.29 -0.6979 -0.9248 3623337 BCB04_000242 COc1ccc(cc1OC)c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M16 compound treatment 4.265073E7 -5.4E7 -2.77 4.9618795E7 -5.9E7 -3.17 -4.2016 -0.9977 3623338 BCB04_000243 COc1ccc(COC[C@]2(NC(=O)N[C@H]3[C@H]2CO[Si](C)(C)C(C)(C)C)Oc4ccccc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M17 compound treatment 9.4299048E7 -2340000.0 -0.12 1.05998237E8 -2570000.0 -0.14 -0.183 -0.9974 3623340 BCB04_000244 COc1ccc(cc1OC)c2cn(CC(=O)N3CCOCC3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M18 compound treatment 9.0298345E7 -6340000.0 -0.33 1.06190085E8 -2380000.0 -0.13 -0.3207 -0.9173 3623341 BCB04_000245 C[C@@]1(Oc2ccccc2[C@@H]3[C@H]1CO)N=C4SCC(=O)N34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M19 compound treatment 9.2176004E7 -4470000.0 -0.23 1.0564609E8 -2930000.0 -0.16 -0.2733 -0.9834 3623343 BCB04_000246 COc1ccc(NC(=O)Cn2cc(nn2)c3ccc(OC)c(OC)c3)cc1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M20 compound treatment 7.8782539E7 -1.79E7 -0.92 9.059453E7 -1.8E7 -0.97 -1.3319 -0.9996 3623344 BCB04_000247 CCOC(=O)[C@@H]1[C@@H]2NC(=S)N(C)[C@@]1(COCc3ccc(OC)cc3)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M21 compound treatment 1.04601386E8 7960000.0 0.41 1.12849161E8 4280000.0 0.23 0.4513 0.9634 3623346 BCB04_000248 COc1ccc(OC)c(NC(=O)Cn2cc(nn2)c3ccc(OC)c(OC)c3)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M22 compound treatment 9.7827132E7 1180000.0 0.06 1.05449188E8 -3120000.0 -0.17 -0.076 -0.4252 3623347 BCB04_000249 CCOC(=O)[C@@H]1[C@@H]2NC(=S)N(C)[C@@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M23 compound treatment 9.6715864E7 73000.0 0.0 1.07153083E8 -1420000.0 -0.08 -0.0514 -0.6717 3623349 BCB04_000250 COc1ccc(cc1OC)c2cn(CC(=O)Nc3nccs3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 M24 compound treatment 1.09255572E8 1.26E7 0.65 1.16858743E8 8290000.0 0.45 0.7726 0.9836 3623350 BCB04_000251 CN1C(=O)N[C@H]2[C@@H](CO)[C@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N01 compound treatment 4.95218E7 -4.71E7 -2.42 4.479918E7 -6.38E7 -3.43 -4.1361 -0.9852 3623352 BCB04_000252 COc1ccc(CN(C2=CCC3C(C2)C(=O)c4ccccc4C3=O)S(=O)(=O)c5ccc(Br)cc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N02 mock treatment 1.14643859E8 1.8E7 0.92 1.25450064E8 1.69E7 0.91 1.295 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N03 compound treatment 1.04150539E8 7510000.0 0.38 1.18813963E8 1.02E7 0.55 0.662 0.9845 3623353 BCB04_000253 CO[C@@](C(=O)OC[C@@H](NC(=O)OC(C)(C)C)C=C)(c1ccccc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N04 mock treatment 1.02198983E8 5560000.0 0.28 1.17928451E8 9360000.0 0.5 0.5576 0.9635 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N05 compound treatment 9.4648471E7 -1990000.0 -0.1 1.13870251E8 5300000.0 0.29 0.1294 0.4271 3623355 BCB04_000254 CO[C@](C(=O)OC[C@@H](NC(=O)OC(C)(C)C)C=C)(c1ccccc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N06 mock treatment 9.3976677E7 -2670000.0 -0.14 1.13521656E8 4950000.0 0.27 0.0918 0.3066 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N07 compound treatment 8.445986E7 -1.22E7 -0.62 9.9610193E7 -8960000.0 -0.48 -0.7828 -0.9919 3623356 BCB04_000255 CC(C)(C)OC(=O)N(CC#CCO[Si](C)(C)C(C)(C)C)S(=O)(=O)c1ccccc1[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N08 mock treatment 9.4780271E7 -1860000.0 -0.1 1.05325026E8 -3250000.0 -0.17 -0.1912 -0.9594 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N09 mock treatment 9.5354886E7 -1290000.0 -0.07 1.06617711E8 -1960000.0 -0.11 -0.1211 -0.9747 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N10 mock treatment 8.8486E7 -8160000.0 -0.42 1.00585137E8 -7990000.0 -0.43 -0.5998 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N11 compound treatment 7.9602059E7 -1.7E7 -0.87 9.5715048E7 -1.29E7 -0.69 -1.1072 -0.9934 3068087 BCB04_000256 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N12 mock treatment 8.9184175E7 -7460000.0 -0.38 1.0353678E8 -5040000.0 -0.27 -0.4621 -0.9859 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N13 mock treatment 9.0599345E7 -6040000.0 -0.31 1.01763589E8 -6810000.0 -0.37 -0.4783 -0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N14 mock treatment 9.1109451E7 -5530000.0 -0.28 1.01180743E8 -7390000.0 -0.4 -0.482 -0.9862 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N15 compound treatment 8.6220967E7 -1.04E7 -0.53 1.05444526E8 -3130000.0 -0.17 -0.4968 -0.8871 3068089 BCB04_000257 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N16 mock treatment 8.8548852E7 -8090000.0 -0.41 1.00118475E8 -8450000.0 -0.46 -0.6153 -0.9989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N17 compound treatment 5.4756274E7 -4.19E7 -2.15 6.163022E7 -4.69E7 -2.53 -3.3055 -0.9967 3623357 BCB04_000258 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N18 mock treatment 9.4037849E7 -2610000.0 -0.13 1.09265473E8 692000.0 0.04 -0.068 -0.4908 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N19 compound treatment 9.3859117E7 -2780000.0 -0.14 1.08311086E8 -262000.0 -0.01 -0.1109 -0.7732 3623358 BCB04_000259 CCOC(=O)/C=C/C(CN(Cc1c(OC)cc(OC)cc1OC)S(=O)(=O)c2ccc(Br)cc2)OC(=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N20 mock treatment 1.05245557E8 8600000.0 0.44 1.12661787E8 4090000.0 0.22 0.4675 0.9485 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N21 compound treatment 6.3640315E7 -3.3E7 -1.69 6.5867545E7 -4.27E7 -2.3 -2.8222 -0.9886 3623360 BCB04_000260 COc1cc(OC)c(CN(C[C@H]2CO2)S(=O)(=O)c3ccc(Br)cc3)c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N22 mock treatment 9.6104552E7 -538000.0 -0.03 1.05758015E8 -2820000.0 -0.15 -0.1267 -0.8223 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N23 compound treatment 9.9411812E7 2770000.0 0.14 1.02548257E8 -6020000.0 -0.32 -0.1291 -0.3645 3623362 BCB04_000261 Brc1ccc(cc1)S(=O)(=O)NCC(OC(=O)c2ccccc2)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 N24 mock treatment 1.11224555E8 1.46E7 0.75 1.16066498E8 7490000.0 0.4 0.8138 0.9582 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O01 compound treatment 1.16533073E8 1.99E7 1.02 1.16658378E8 8090000.0 0.44 1.0287 0.928 3623363 BCB04_000262 COc1ccc(cc1OC)c2cn(CC(=O)Nc3ccon3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O02 compound treatment 1.04741946E8 8100000.0 0.42 1.11341604E8 2770000.0 0.15 0.3989 0.9045 3623364 BCB04_000263 CN1C(=S)N[C@H]2[C@@H](CO)[C@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O03 compound treatment 1.02067421E8 5420000.0 0.28 1.0460008E8 -3970000.0 -0.21 0.0453 0.1291 3623366 BCB04_000264 COc1ccc(cc1OC)c2cn(C[C@H](Cc3ccccc3)NC(=O)Nc4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O04 compound treatment 8.6951071E7 -9690000.0 -0.5 1.14787497E8 6210000.0 0.33 -0.1146 -0.1913 3623368 BCB04_000265 CN1C(=O)N[C@H]2[C@@H](CO[Si](C)(C)C(C)(C)C)[C@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O05 compound treatment 9.9842236E7 3200000.0 0.16 1.13659927E8 5090000.0 0.27 0.3096 0.9699 3623370 BCB04_000266 COc1ccc(cc1OC)c2cn(C[C@@H](Cc3ccccc3)NC(=O)Nc4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O06 compound treatment 8.698289E7 -9660000.0 -0.5 9.9475177E7 -9100000.0 -0.49 -0.6965 -1.0 3623371 BCB04_000267 CN1C(=S)N[C@H]2[C@@H](CO[Si](C)(C)C(C)(C)C)[C@]1(C)Oc3ccccc23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O07 compound treatment 9.4903457E7 -1740000.0 -0.09 1.13504584E8 4930000.0 0.27 0.1247 0.4453 3623373 BCB04_000268 COc1ccc(cc1OC)c2cn(C[C@H](Cc3ccccc3)NC(=O)c4ccccc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O08 compound treatment 7.0222943E7 -2.64E7 -1.35 7.6740526E7 -3.18E7 -1.71 -2.1696 -0.9932 3623375 BCB04_000269 CN1C(=O)N([C@H]2[C@@H](CO[Si](C)(C)C(C)(C)C)[C@]1(C)Oc3ccccc23)C(=O)CC(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O09 compound treatment 8.5544022E7 -1.11E7 -0.57 1.08533435E8 -39600.0 0.0 -0.4037 -0.7098 3623377 BCB04_000270 COc1ccc(cc1OC)c2cn(CCCNC(=O)Nc3ccccc3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O10 compound treatment 8.3327879E7 -1.33E7 -0.68 1.02338675E8 -6230000.0 -0.34 -0.7199 -0.9466 3623378 BCB04_000271 CN1C(=O)N[C@H]2[C@@H](COC(=O)c3ccccc3)[C@]1(C)Oc4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O11 mock treatment 8.9284715E7 -7360000.0 -0.38 1.13545755E8 4970000.0 0.27 -0.0773 -0.1672 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O12 mock treatment 1.01798038E8 5160000.0 0.26 1.10270243E8 1700000.0 0.09 0.2515 0.8994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O13 compound treatment 8.416177E7 -1.25E7 -0.64 8.3245655E7 -2.53E7 -1.36 -1.4168 -0.9404 3623380 BCB04_000272 COc1ccc(cc1OC)c2cn(CCNC(=O)Nc3ccccc3)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O14 compound treatment 9.0175352E7 -6470000.0 -0.33 1.03562734E8 -5010000.0 -0.27 -0.4252 -0.9948 3623381 BCB04_000273 CN1C(=O)N([C@H]2[C@@H](COC(=O)c3ccccc3)[C@]1(C)Oc4ccccc24)C(=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O15 compound treatment 8.9383902E7 -7260000.0 -0.37 1.08605038E8 32000.0 0.0 -0.2619 -0.7038 3623383 BCB04_000274 COc1ccc(cc1OC)c2cn(CCCNC(=O)[C@H](Cc3ccccc3)NS(=O)(=O)c4ccc(C)cc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O16 compound treatment 9.0067015E7 -6580000.0 -0.34 1.02351698E8 -6220000.0 -0.34 -0.4752 -1.0 3623385 BCB04_000275 CN1C(=O)N([C@H]2[C@@H](COC(=O)c3ccccc3)[C@]1(C)Oc4ccccc24)C(=O)CC(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O17 compound treatment 9.7141017E7 498000.0 0.03 1.05551595E8 -3020000.0 -0.16 -0.097 -0.589 3623387 BCB04_000276 COc1ccc(cc1OC)c2cn(CCNC(=O)[C@H](Cc3ccccc3)NS(=O)(=O)c4ccc(C)cc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O18 compound treatment 4.4176924E7 -5.25E7 -2.69 4.8397633E7 -6.02E7 -3.24 -4.1928 -0.9957 3623389 BCB04_000277 COc1ccc(COC[C@]2(NC(=S)N[C@H]3[C@H]2CO[Si](C)(C)C(C)(C)C)Oc4ccccc34)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O19 compound treatment 9.377836E7 -2860000.0 -0.15 9.8778568E7 -9790000.0 -0.53 -0.4768 -0.8708 3623391 BCB04_000278 COc1ccc(cc1OC)c2cn(CCNC(=O)[C@@H](NS(=O)(=O)c3ccc(C)cc3)C(C)C)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O20 compound treatment 6.1899706E7 -3.47E7 -1.78 6.6726179E7 -4.18E7 -2.25 -2.8526 -0.9932 3623393 BCB04_000279 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=O)N2C)[C@@H]4CO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O21 compound treatment 1.03907764E8 7260000.0 0.37 1.1284822E8 4280000.0 0.23 0.4261 0.9733 3623395 BCB04_000280 COc1ccc(cc1OC)c2cn(C[C@@H]3CCCN3S(=O)(=O)c4ccc(C)cc4)nn2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O22 compound treatment 9.5302429E7 -1340000.0 -0.07 1.04016269E8 -4560000.0 -0.25 -0.2221 -0.8716 3623397 BCB04_000281 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N=C5SCc6ccccc6CN45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O23 compound treatment 6.9099402E7 -2.75E7 -1.41 7.8403937E7 -3.02E7 -1.62 -2.147 -0.9975 3623399 BCB04_000282 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)c3ccc(OC)c(OC)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 O24 compound treatment 7.5949981E7 -2.07E7 -1.06 7.8871099E7 -2.97E7 -1.6 -1.8809 -0.9801 3623401 BCB04_000283 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=O)N2C)[C@@H]4COC(=O)c5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P01 compound treatment 1.28134194E8 3.15E7 1.61 1.18237836E8 9660000.0 0.52 1.5093 0.89 3616028 BCB04_000284 COc1cc(OC)c(CN(CC#CCO)S(=O)(=O)c2ccccc2[N+](=O)[O-])c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P02 mock treatment 1.16208084E8 1.96E7 1.0 1.2432533E8 1.58E7 0.85 1.3089 0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P03 compound treatment 1.10515387E8 1.39E7 0.71 1.20312686E8 1.17E7 0.63 0.9498 0.9983 3623403 BCB04_000285 COc1cc(OC)c(CN(CC#CCN(CC(OC(=O)c2ccccc2)C=C)S(=O)(=O)c3c(OC)cc(OC)cc3OC)S(=O)(=O)c4ccccc4[N+](=O)[O-])c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P04 mock treatment 1.05330516E8 8690000.0 0.45 1.0916527E8 592000.0 0.03 0.3374 0.7558 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P05 compound treatment 9.7894903E7 1250000.0 0.06 1.12409816E8 3840000.0 0.21 0.1915 0.885 3623404 BCB04_000286 CCOC(=O)/C=C/C(CN(CC#CCN(Cc1c(OC)cc(OC)cc1OC)S(=O)(=O)c2ccccc2[N+](=O)[O-])S(=O)(=O)c3c(OC)cc(OC)cc3OC)OC(=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P06 mock treatment 1.03747703E8 7100000.0 0.36 1.1529005E8 6720000.0 0.36 0.5133 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P07 compound treatment 9.2948407E7 -3690000.0 -0.19 1.09326696E8 754000.0 0.04 -0.1052 -0.5432 3623406 BCB04_000287 COc1cc(OC)c(CN(CC#CCOC(=O)c2ccccc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P08 mock treatment 1.06399576E8 9760000.0 0.5 1.00927921E8 -7650000.0 -0.41 0.0625 0.0965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P09 compound treatment 9.4596492E7 -2050000.0 -0.1 1.12354165E8 3780000.0 0.2 0.0698 0.3048 3623407 BCB04_000288 CCOC(=O)/C=C/C(CNS(=O)(=O)c1ccc(Br)cc1)OC(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P10 mock treatment 1.01029498E8 4390000.0 0.22 1.08795191E8 222000.0 0.01 0.1674 0.7437 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P11 mock treatment 1.07506216E8 1.09E7 0.56 1.12504412E8 3930000.0 0.21 0.5434 0.9123 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P12 mock treatment 9.461084E7 -2030000.0 -0.1 1.03390721E8 -5180000.0 -0.28 -0.271 -0.9097 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P13 compound treatment 9.6879512E7 237000.0 0.01 1.04547892E8 -4030000.0 -0.22 -0.1447 -0.6665 3623409 BCB04_000289 COc1cc(OC)c(CNS(=O)(=O)c2ccccc2[N+](=O)[O-])c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P14 mock treatment 9.9644431E7 3000000.0 0.15 1.01925483E8 -6650000.0 -0.36 -0.1443 -0.3705 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P15 compound treatment 7.2805844E7 -2.38E7 -1.22 7.2149799E7 -3.64E7 -1.96 -2.2508 -0.974 3623410 BCB04_000290 CCOC(=O)/C=C/C(O)CN(Cc1c(OC)cc(OC)cc1OC)S(=O)(=O)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P16 mock treatment 9.8870589E7 2230000.0 0.11 1.01908019E8 -6670000.0 -0.36 -0.1731 -0.4595 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P17 compound treatment 8.872474E7 -7920000.0 -0.41 9.2257323E7 -1.63E7 -0.88 -0.9082 -0.9384 3623412 BCB04_000291 COc1cc(OC)c(CN(CC(O)C=C)S(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P18 mock treatment 1.02984045E8 6340000.0 0.32 1.04003661E8 -4570000.0 -0.25 0.0558 0.1369 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P19 compound treatment 1.02808645E8 6170000.0 0.32 9.9074109E7 -9500000.0 -0.51 -0.1383 -0.2299 3623413 BCB04_000292 COc1cc(OC)c(CN(CC#CCN(CC#CCOC(=O)c2ccccc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])S(=O)(=O)c4ccccc4[N+](=O)[O-])c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P20 mock treatment 1.02595723E8 5950000.0 0.31 1.06401899E8 -2170000.0 -0.12 0.1331 0.4073 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P21 compound treatment 9.6959121E7 316000.0 0.02 1.05100741E8 -3470000.0 -0.19 -0.1208 -0.6434 3623414 BCB04_000293 CC(C)(C)OC(=O)NCC1=C2CN(CC2=C3CN(C(COC(=O)c4ccccc4)C3C1)S(=O)(=O)c5ccc(Br)cc5)S(=O)(=O)c6ccccc6[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P22 mock treatment 1.06063665E8 9420000.0 0.48 1.1373582E8 5160000.0 0.28 0.538 0.9656 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P23 compound treatment 1.20661803E8 2.4E7 1.23 1.20108271E8 1.15E7 0.62 1.3097 0.9498 3623415 BCB04_000294 CC(C)(C)OC(=O)N[C@@H]1CN(CC2=C1C[C@H](COC(=O)c3ccccc3)C4=C2CN(C4)S(=O)(=O)c5ccc(Br)cc5)S(=O)(=O)c6ccccc6[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2319 P24 mock treatment 1.21825798E8 2.52E7 1.29 1.26508966E8 1.79E7 0.97 1.5956 0.9898 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A01 compound treatment 1.3850944E8 3.48E7 1.78 1.35116904E8 3.27E7 1.76 2.5042 1.0 DHPC8.2_000001 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A02 compound treatment 1.3307297E8 2.94E7 1.5 1.27221556E8 2.48E7 1.33 2.0065 0.9982 DHPC8.2_000002 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A03 compound treatment 1.29922096E8 2.62E7 1.34 1.21392786E8 1.89E7 1.02 1.6704 0.9908 DHPC8.2_000003 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A04 compound treatment 1.37940877E8 3.42E7 1.75 1.34967356E8 3.25E7 1.75 2.4779 1.0 DHPC8.2_000004 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A05 compound treatment 1.27586408E8 2.39E7 1.22 1.1813883E8 1.57E7 0.84 1.4618 0.9836 DHPC8.2_000005 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A06 compound treatment 1.22596109E8 1.89E7 0.97 1.14446545E8 1.2E7 0.65 1.1404 0.9807 DHPC8.2_000006 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A07 compound treatment 1.21717063E8 1.8E7 0.92 1.13554235E8 1.11E7 0.6 1.0745 0.9779 DHPC8.2_000007 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A08 compound treatment 1.28896958E8 2.52E7 1.29 1.16546646E8 1.41E7 0.76 1.4487 0.9679 DHPC8.2_000008 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A09 compound treatment 1.10752528E8 7030000.0 0.36 1.09185401E8 6720000.0 0.36 0.5108 1.0 DHPC8.2_000009 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A10 compound treatment 1.21656705E8 1.79E7 0.92 1.10656127E8 8190000.0 0.44 0.962 0.9435 DHPC8.2_000010 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A11 compound treatment 1.13613959E8 9890000.0 0.51 1.15654381E8 1.32E7 0.71 0.8608 0.9863 DHPC8.2_000011 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A12 compound treatment 1.19917315E8 1.62E7 0.83 1.14187333E8 1.17E7 0.63 1.0334 0.9909 DHPC8.2_000012 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A13 mock treatment 1.25639393E8 2.19E7 1.12 1.28803274E8 2.63E7 1.42 1.7973 0.9933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A14 mock treatment 1.18257203E8 1.45E7 0.74 1.11317218E8 8860000.0 0.48 0.8639 0.9768 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A15 compound treatment 1.16419856E8 1.27E7 0.65 1.0769148E8 5230000.0 0.28 0.6593 0.9298 DHPC8.2_000013 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A16 compound treatment 1.18258053E8 1.45E7 0.74 1.13557658E8 1.11E7 0.6 0.9493 0.994 DHPC8.2_000014 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A17 compound treatment 9.5967424E7 -7760000.0 -0.4 1.03690736E8 1230000.0 0.07 -0.2343 -0.5814 DHPC8.2_000015 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A18 compound treatment 1.29122661E8 2.54E7 1.3 1.22514472E8 2.01E7 1.08 1.6841 0.9957 DHPC8.2_000016 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A19 compound treatment 2.8885721E7 -7.48E7 -3.84 6.4622536E7 -3.78E7 -2.04 -4.153 -0.9562 DHPC8.2_000017 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A20 compound treatment 1.21083147E8 1.74E7 0.89 1.12713342E8 1.03E7 0.55 1.0195 0.9736 DHPC8.2_000018 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A21 compound treatment 1.02093138E8 -1630000.0 -0.08 1.00254925E8 -2210000.0 -0.12 -0.1431 -0.9851 DHPC8.2_000019 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A22 compound treatment 1.13695679E8 9970000.0 0.51 1.06959165E8 4500000.0 0.24 0.5327 0.9418 DHPC8.2_000020 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A23 compound treatment 1.26192697E8 2.25E7 1.15 1.1843611E8 1.6E7 0.86 1.4226 0.9897 DHPC8.2_000021 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 A24 compound treatment 1.32784592E8 2.91E7 1.49 1.35185651E8 3.27E7 1.76 2.2993 0.9965 DHPC8.2_000022 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B01 mock treatment 1.42088691E8 3.84E7 1.97 1.37367398E8 3.49E7 1.88 2.7196 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B02 mock treatment 1.19908427E8 1.62E7 0.83 1.16295606E8 1.38E7 0.74 1.1134 0.9986 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B03 mock treatment 1.15835078E8 1.21E7 0.62 1.08321099E8 5860000.0 0.32 0.6621 0.9507 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B04 mock treatment 1.13467573E8 9740000.0 0.5 1.06596063E8 4130000.0 0.22 0.5106 0.9337 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B05 mock treatment 1.1063554E8 6910000.0 0.35 1.07970487E8 5510000.0 0.3 0.4603 0.9961 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B06 mock treatment 1.0839423E8 4670000.0 0.24 1.02329734E8 -132000.0 -0.01 0.1643 0.6858 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B07 mock treatment 1.15591323E8 1.19E7 0.61 1.15738656E8 1.33E7 0.71 0.9357 0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B08 mock treatment 1.10496207E8 6770000.0 0.35 1.02172639E8 -289000.0 -0.02 0.2345 0.6747 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B09 mock treatment 1.07069056E8 3350000.0 0.17 1.0591965E8 3460000.0 0.19 0.2529 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B10 mock treatment 1.06811963E8 3090000.0 0.16 9.7109909E7 -5350000.0 -0.29 -0.0918 -0.2793 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B11 mock treatment 1.02913009E8 -810000.0 -0.04 9.7840695E7 -4620000.0 -0.25 -0.2053 -0.8138 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B12 mock treatment 1.04561839E8 839000.0 0.04 1.04183661E8 1720000.0 0.09 0.096 0.939 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B13 mock treatment 1.08074291E8 4350000.0 0.22 9.7820636E7 -4640000.0 -0.25 -0.019 -0.0568 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B14 mock treatment 1.05712194E8 1990000.0 0.1 9.7933285E7 -4530000.0 -0.24 -0.1003 -0.3796 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B15 mock treatment 1.07662383E8 3940000.0 0.2 1.00302751E8 -2160000.0 -0.12 0.0606 0.2599 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B16 mock treatment 1.06839841E8 3120000.0 0.16 9.857331E7 -3890000.0 -0.21 -0.0351 -0.1333 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B17 mock treatment 1.05635209E8 1910000.0 0.1 9.5700472E7 -6760000.0 -0.36 -0.1881 -0.499 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B18 mock treatment 1.08500757E8 4780000.0 0.24 9.8806429E7 -3660000.0 -0.2 0.034 0.1081 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B19 mock treatment 1.07402089E8 3680000.0 0.19 9.9065887E7 -3400000.0 -0.18 0.004 0.0154 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B20 mock treatment 1.19529157E8 1.58E7 0.81 1.14581031E8 1.21E7 0.65 1.0343 0.9943 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B21 mock treatment 1.09698421E8 5980000.0 0.31 1.02134739E8 -327000.0 -0.02 0.2041 0.6653 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B22 mock treatment 1.06792609E8 3070000.0 0.16 1.05592924E8 3130000.0 0.17 0.2305 0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B23 mock treatment 1.14581328E8 1.09E7 0.56 1.11441795E8 8980000.0 0.48 0.7355 0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 B24 mock treatment 1.18934914E8 1.52E7 0.78 1.20315073E8 1.79E7 0.96 1.2311 0.9946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C01 compound treatment 1.28819793E8 2.51E7 1.29 1.19026863E8 1.66E7 0.89 1.5403 0.984 DHPC8.2_000023 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C02 compound treatment 1.15448846E8 1.17E7 0.6 1.11799226E8 9340000.0 0.5 0.7805 0.9961 DHPC8.2_000024 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C03 compound treatment 1.15834419E8 1.21E7 0.62 1.10787664E8 8330000.0 0.45 0.756 0.9872 DHPC8.2_000025 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C04 compound treatment 1.15037145E8 1.13E7 0.58 1.08944091E8 6480000.0 0.35 0.6569 0.9705 DHPC8.2_000026 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C05 compound treatment 1.11895677E8 8170000.0 0.42 1.07854002E8 5390000.0 0.29 0.5015 0.984 DHPC8.2_000027 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C06 compound treatment 1.10447315E8 6720000.0 0.34 1.02747949E8 286000.0 0.02 0.2546 0.738 DHPC8.2_000028 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C07 compound treatment 1.06599532E8 2880000.0 0.15 1.15393914E8 1.29E7 0.7 0.5967 0.8382 DHPC8.2_000029 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C08 compound treatment 6.5565448E7 -3.82E7 -1.96 6.2317453E7 -4.01E7 -2.16 -2.9115 -0.9987 DHPC8.2_000030 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C09 compound treatment 1.12056609E8 8330000.0 0.43 1.10583228E8 8120000.0 0.44 0.6113 0.9999 DHPC8.2_000031 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C10 compound treatment 1.03969133E8 246000.0 0.01 9.8869058E7 -3590000.0 -0.19 -0.1279 -0.6595 DHPC8.2_000032 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C11 mock treatment 1.09264989E8 5540000.0 0.28 1.11606816E8 9150000.0 0.49 0.5491 0.9658 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C12 mock treatment 1.0461676E8 894000.0 0.05 1.08283748E8 5820000.0 0.31 0.2541 0.8019 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C13 compound treatment 1.04104906E8 382000.0 0.02 1.08519381E8 6060000.0 0.33 0.2445 0.7482 DHPC8.2_000033 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C14 compound treatment 1.05219401E8 1500000.0 0.08 9.5922724E7 -6540000.0 -0.35 -0.1948 -0.5404 DHPC8.2_000034 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C15 mock treatment 1.02840294E8 -882000.0 -0.05 9.3691849E7 -8770000.0 -0.47 -0.3659 -0.7713 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C16 mock treatment 9.8960312E7 -4760000.0 -0.24 8.9505505E7 -1.3E7 -0.7 -0.6659 -0.9009 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C17 compound treatment 1.0791569E8 4190000.0 0.21 1.05283154E8 2820000.0 0.15 0.2594 0.9856 DHPC8.2_000035 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C18 compound treatment 1.02945052E8 -778000.0 -0.04 9.2418139E7 -1.0E7 -0.54 -0.4106 -0.7572 DHPC8.2_000036 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C19 compound treatment 1.01104051E8 -2620000.0 -0.13 9.3837699E7 -8620000.0 -0.46 -0.4233 -0.8756 DHPC8.2_000037 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C20 compound treatment 1.03438726E8 -284000.0 -0.01 9.5136976E7 -7320000.0 -0.39 -0.2892 -0.7327 DHPC8.2_000038 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C21 compound treatment 1.07380323E8 3660000.0 0.19 1.03525704E8 1060000.0 0.06 0.1731 0.8829 DHPC8.2_000039 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C22 compound treatment 1.0669647E8 2970000.0 0.15 1.02528707E8 66900.0 0.0 0.1103 0.7236 DHPC8.2_000040 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C23 compound treatment 1.06307137E8 2580000.0 0.13 1.04807345E8 2350000.0 0.13 0.183 0.9997 DHPC8.2_000041 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 C24 compound treatment 1.2262678E8 1.89E7 0.97 1.19412635E8 1.7E7 0.91 1.3306 0.9996 DHPC8.2_000042 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D01 mock treatment 1.23517058E8 1.98E7 1.01 1.14053241E8 1.16E7 0.62 1.1588 0.9728 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D02 mock treatment 1.11137314E8 7410000.0 0.38 1.06288762E8 3830000.0 0.21 0.4144 0.9587 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D03 mock treatment 1.1870963E8 1.5E7 0.77 1.20900579E8 1.84E7 0.99 1.2453 0.9919 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D04 mock treatment 1.14888168E8 1.12E7 0.57 1.11944069E8 9480000.0 0.51 0.7657 0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D05 mock treatment 1.13797189E8 1.01E7 0.52 1.13410652E8 1.09E7 0.59 0.782 0.9978 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D06 mock treatment 1.13569935E8 9850000.0 0.5 1.10001927E8 7540000.0 0.41 0.644 0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D07 mock treatment 1.07918147E8 4200000.0 0.22 1.07614202E8 5150000.0 0.28 0.3482 0.9921 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D08 mock treatment 1.07397728E8 3680000.0 0.19 1.02031719E8 -430000.0 -0.02 0.1168 0.6155 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D09 mock treatment 1.03126634E8 -596000.0 -0.03 1.02311526E8 -150000.0 -0.01 -0.0273 -0.8646 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D10 mock treatment 1.01472515E8 -2250000.0 -0.12 1.02854565E8 393000.0 0.02 -0.0666 -0.568 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D11 mock treatment 9.8624245E7 -5100000.0 -0.26 1.01492879E8 -969000.0 -0.05 -0.2217 -0.8319 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D12 mock treatment 1.0932421E8 5600000.0 0.29 1.08222059E8 5760000.0 0.31 0.4223 0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D13 mock treatment 1.09426918E8 5700000.0 0.29 1.07193077E8 4730000.0 0.25 0.3869 0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D14 mock treatment 9.8851298E7 -4870000.0 -0.25 9.8851602E7 -3610000.0 -0.19 -0.314 -0.9923 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D15 mock treatment 1.03837263E8 115000.0 0.01 1.01858628E8 -603000.0 -0.03 -0.0188 -0.57 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D16 mock treatment 1.08656513E8 4930000.0 0.25 1.02913491E8 452000.0 0.02 0.196 0.7716 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D17 mock treatment 9.7123138E7 -6600000.0 -0.34 9.2106215E7 -1.04E7 -0.56 -0.6335 -0.9713 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D18 mock treatment 1.04347107E8 624000.0 0.03 1.0264673E8 185000.0 0.01 0.0297 0.8853 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D19 mock treatment 1.0165795E8 -2060000.0 -0.11 1.04687501E8 2230000.0 0.12 0.0099 0.0621 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D20 mock treatment 1.01349931E8 -2370000.0 -0.12 9.5783626E7 -6680000.0 -0.36 -0.3403 -0.8964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D21 mock treatment 1.02317477E8 -1410000.0 -0.07 9.7352206E7 -5110000.0 -0.28 -0.2455 -0.8631 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D22 mock treatment 9.8440594E7 -5280000.0 -0.27 1.05437678E8 2980000.0 0.16 -0.0781 -0.2483 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D23 mock treatment 1.00168299E8 -3550000.0 -0.18 9.9783144E7 -2680000.0 -0.14 -0.2308 -0.9933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 D24 mock treatment 1.04952212E8 1230000.0 0.06 1.14429071E8 1.2E7 0.64 0.5003 0.7726 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E01 mock treatment 1.24572038E8 2.08E7 1.07 1.15433012E8 1.3E7 0.7 1.2495 0.9788 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E02 mock treatment 1.15159234E8 1.14E7 0.59 1.08942428E8 6480000.0 0.35 0.6612 0.9693 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E03 compound treatment 1.24531556E8 2.08E7 1.07 1.20997079E8 1.85E7 1.0 1.4599 0.9995 DHPC8.2_000043 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E04 compound treatment 1.2418466E8 2.05E7 1.05 1.16407412E8 1.39E7 0.75 1.2726 0.9866 DHPC8.2_000044 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E05 compound treatment 1.14866658E8 1.11E7 0.57 1.07025845E8 4560000.0 0.25 0.5777 0.929 DHPC8.2_000045 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E06 compound treatment 1.18361257E8 1.46E7 0.75 1.15694419E8 1.32E7 0.71 1.0344 0.9997 DHPC8.2_000046 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E07 compound treatment 1.05327373E8 1600000.0 0.08 1.06685077E8 4220000.0 0.23 0.219 0.9054 DHPC8.2_000047 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E08 compound treatment 1.16301918E8 1.26E7 0.64 1.13170795E8 1.07E7 0.58 0.8637 0.9985 DHPC8.2_000048 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E09 mock treatment 1.09969089E8 6250000.0 0.32 1.03264639E8 803000.0 0.04 0.2569 0.7954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E10 mock treatment 1.02955322E8 -767000.0 -0.04 1.02549078E8 87300.0 0.0 -0.0245 -0.6182 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E11 compound treatment 1.0356856E8 -154000.0 -0.01 1.0285745E8 396000.0 0.02 0.0095 0.4172 DHPC8.2_000049 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E12 compound treatment 1.07302553E8 3580000.0 0.18 1.07410745E8 4950000.0 0.27 0.3182 0.9834 DHPC8.2_000050 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E13 compound treatment 1.03961599E8 239000.0 0.01 1.00730106E8 -1730000.0 -0.09 -0.0573 -0.609 DHPC8.2_000051 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E14 compound treatment 9.7122925E7 -6600000.0 -0.34 9.5395293E7 -7070000.0 -0.38 -0.5083 -0.9983 DHPC8.2_000052 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E15 compound treatment 1.01250956E8 -2470000.0 -0.13 9.830687E7 -4150000.0 -0.22 -0.2478 -0.9637 DHPC8.2_000053 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E16 compound treatment 1.00984669E8 -2740000.0 -0.14 1.01105425E8 -1360000.0 -0.07 -0.1509 -0.9537 DHPC8.2_000054 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E17 mock treatment 1.03979056E8 256000.0 0.01 1.00438979E8 -2020000.0 -0.11 -0.0677 -0.6173 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E18 mock treatment 1.04553218E8 831000.0 0.04 1.01431081E8 -1030000.0 -0.06 -0.0091 -0.1308 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E19 compound treatment 1.00493387E8 -3230000.0 -0.17 1.00110437E8 -2350000.0 -0.13 -0.2066 -0.9913 DHPC8.2_000055 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E20 compound treatment 1.01987654E8 -1740000.0 -0.09 1.04583287E8 2120000.0 0.11 0.0179 0.1237 DHPC8.2_000056 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E21 compound treatment 1.00029237E8 -3690000.0 -0.19 9.6721345E7 -5740000.0 -0.31 -0.3524 -0.9723 DHPC8.2_000057 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E22 compound treatment 1.09390649E8 5670000.0 0.29 1.08238004E8 5780000.0 0.31 0.4254 0.9994 DHPC8.2_000058 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E23 compound treatment 1.00357226E8 -3370000.0 -0.17 1.05619982E8 3160000.0 0.17 -0.0017 -0.0071 DHPC8.2_000059 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 E24 compound treatment 1.09011895E8 5290000.0 0.27 1.04547027E8 2090000.0 0.11 0.2711 0.9239 DHPC8.2_000060 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F01 mock treatment 1.29706841E8 2.6E7 1.33 1.21816468E8 1.94E7 1.04 1.6787 0.9926 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F02 mock treatment 1.25390234E8 2.17E7 1.11 1.2303205E8 2.06E7 1.11 1.5685 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F03 mock treatment 1.15516383E8 1.18E7 0.6 1.14698333E8 1.22E7 0.66 0.8934 0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F04 mock treatment 1.17428103E8 1.37E7 0.7 1.14131967E8 1.17E7 0.63 0.9411 0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F05 mock treatment 1.12295664E8 8570000.0 0.44 1.09585116E8 7120000.0 0.38 0.5819 0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F06 mock treatment 1.14018095E8 1.03E7 0.53 1.11462567E8 9000000.0 0.48 0.7159 0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F07 mock treatment 1.15260767E8 1.15E7 0.59 1.13745791E8 1.13E7 0.61 0.8478 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F08 mock treatment 1.09183621E8 5460000.0 0.28 1.05624935E8 3160000.0 0.17 0.3184 0.9717 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F09 mock treatment 1.11518476E8 7800000.0 0.4 1.07978317E8 5520000.0 0.3 0.4926 0.9894 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F10 mock treatment 1.02839829E8 -883000.0 -0.05 1.05462566E8 3000000.0 0.16 0.0823 0.4903 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F11 mock treatment 1.08266787E8 4540000.0 0.23 1.05898523E8 3440000.0 0.19 0.2955 0.9935 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F12 mock treatment 1.03026892E8 -696000.0 -0.04 1.02318789E8 -143000.0 -0.01 -0.0307 -0.8404 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F13 mock treatment 1.01499109E8 -2220000.0 -0.11 9.9579675E7 -2880000.0 -0.16 -0.1903 -0.9885 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F14 mock treatment 1.0580517E8 2080000.0 0.11 1.02425512E8 -36300.0 0.0 0.0741 0.694 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F15 mock treatment 1.02357539E8 -1370000.0 -0.07 9.8596025E7 -3870000.0 -0.21 -0.1967 -0.8955 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F16 mock treatment 9.6240194E7 -7480000.0 -0.38 9.4683009E7 -7780000.0 -0.42 -0.5674 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F17 mock treatment 9.9592882E7 -4130000.0 -0.21 9.8399138E7 -4060000.0 -0.22 -0.3044 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F18 mock treatment 1.0537946E8 1660000.0 0.08 9.9517823E7 -2940000.0 -0.16 -0.0521 -0.2895 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F19 mock treatment 1.03305119E8 -418000.0 -0.02 9.9351585E7 -3110000.0 -0.17 -0.1336 -0.791 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F20 mock treatment 1.05715487E8 1990000.0 0.1 1.02459563E8 -2240.0 0.0 0.0721 0.7063 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F21 mock treatment 1.01508653E8 -2210000.0 -0.11 1.01460137E8 -1000000.0 -0.05 -0.1184 -0.9422 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F22 mock treatment 9.9092029E7 -4630000.0 -0.24 1.02483274E8 21500.0 0.0 -0.167 -0.7037 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F23 mock treatment 1.01564562E8 -2160000.0 -0.11 9.9643317E7 -2820000.0 -0.15 -0.1855 -0.9879 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 F24 mock treatment 1.22517578E8 1.88E7 0.96 1.19099048E8 1.66E7 0.9 1.3147 0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G01 compound treatment 1.23304348E8 1.96E7 1.0 1.15176939E8 1.27E7 0.68 1.1938 0.9826 DHPC8.2_000061 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G02 compound treatment 1.20270064E8 1.65E7 0.85 1.18118164E8 1.57E7 0.84 1.1959 1.0 DHPC8.2_000062 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G03 mock treatment 1.25043716E8 2.13E7 1.09 1.17928159E8 1.55E7 0.83 1.3616 0.991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G04 mock treatment 1.22106877E8 1.84E7 0.94 1.1983474E8 1.74E7 0.94 1.3278 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G05 compound treatment 1.17875797E8 1.42E7 0.73 1.17077951E8 1.46E7 0.79 1.0695 0.9992 DHPC8.2_000063 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G06 compound treatment 1.18669939E8 1.49E7 0.77 1.13431092E8 1.1E7 0.59 0.9594 0.9917 DHPC8.2_000064 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G07 compound treatment 1.04419113E8 696000.0 0.04 1.09792806E8 7330000.0 0.39 0.3044 0.7679 DHPC8.2_000065 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G08 compound treatment 1.13937244E8 1.02E7 0.52 1.10554042E8 8090000.0 0.44 0.6783 0.9958 DHPC8.2_000066 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G09 compound treatment 1.08320739E8 4600000.0 0.24 1.0469956E8 2240000.0 0.12 0.2518 0.9515 DHPC8.2_000067 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G10 compound treatment 1.10271857E8 6550000.0 0.34 1.07011005E8 4550000.0 0.24 0.4106 0.988 DHPC8.2_000068 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G11 compound treatment 1.0692902E8 3210000.0 0.16 1.04986729E8 2520000.0 0.14 0.2123 0.9956 DHPC8.2_000069 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G12 compound treatment 9.6289807E7 -7430000.0 -0.38 1.01773124E8 -689000.0 -0.04 -0.2956 -0.7723 DHPC8.2_000070 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G13 compound treatment 1.03531197E8 -191000.0 -0.01 1.01155853E8 -1310000.0 -0.07 -0.0567 -0.798 DHPC8.2_000071 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G14 compound treatment 1.03224015E8 -499000.0 -0.03 9.993081E7 -2530000.0 -0.14 -0.1144 -0.8253 DHPC8.2_000072 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G15 compound treatment 9.8933008E7 -4790000.0 -0.25 1.00559254E8 -1900000.0 -0.1 -0.246 -0.9249 DHPC8.2_000073 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G16 compound treatment 1.01989694E8 -1730000.0 -0.09 9.492793E7 -7530000.0 -0.41 -0.3497 -0.842 DHPC8.2_000074 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G17 compound treatment 9.8093847E7 -5630000.0 -0.29 9.6173809E7 -6290000.0 -0.34 -0.4434 -0.9968 DHPC8.2_000075 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G18 compound treatment 1.01444163E8 -2280000.0 -0.12 9.5592684E7 -6870000.0 -0.37 -0.3441 -0.8872 DHPC8.2_000076 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G19 mock treatment 9.6140462E7 -7580000.0 -0.39 9.7406251E7 -5060000.0 -0.27 -0.4673 -0.9848 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G20 mock treatment 1.00913815E8 -2810000.0 -0.14 1.00774876E8 -1690000.0 -0.09 -0.166 -0.9754 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G21 compound treatment 1.00498554E8 -3220000.0 -0.17 1.01479013E8 -983000.0 -0.05 -0.1543 -0.8891 DHPC8.2_000077 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G22 compound treatment 1.02594635E8 -1130000.0 -0.06 1.08759218E8 6300000.0 0.34 0.1989 0.5782 DHPC8.2_000078 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G23 compound treatment 9.2902539E7 -1.08E7 -0.55 1.02451427E8 -10400.0 0.0 -0.3925 -0.7078 DHPC8.2_000079 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 G24 mock treatment 1.00433703E8 -3290000.0 -0.17 1.21695739E8 1.92E7 1.04 0.6132 0.5843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H01 mock treatment 1.1779023E8 1.41E7 0.72 1.16824594E8 1.44E7 0.77 1.0567 0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H02 mock treatment 1.15187533E8 1.15E7 0.59 1.12661004E8 1.02E7 0.55 0.8039 0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H03 mock treatment 1.20765442E8 1.7E7 0.87 1.18510594E8 1.6E7 0.86 1.2288 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H04 mock treatment 1.15360479E8 1.16E7 0.6 1.09085562E8 6620000.0 0.36 0.674 0.9698 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H05 mock treatment 1.14830011E8 1.11E7 0.57 1.11864E8 9400000.0 0.51 0.7606 0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H06 mock treatment 1.1571315E8 1.2E7 0.61 1.11896427E8 9430000.0 0.51 0.7938 0.9955 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H07 mock treatment 1.13176457E8 9450000.0 0.48 1.12003384E8 9540000.0 0.51 0.7059 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H08 mock treatment 1.09489301E8 5770000.0 0.3 1.0469635E8 2230000.0 0.12 0.2941 0.9215 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H09 mock treatment 1.07838374E8 4120000.0 0.21 1.06377789E8 3920000.0 0.21 0.2983 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H10 mock treatment 1.09049961E8 5330000.0 0.27 1.05383463E8 2920000.0 0.16 0.3043 0.9657 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H11 mock treatment 1.00569417E8 -3150000.0 -0.16 9.8255466E7 -4210000.0 -0.23 -0.2744 -0.9863 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H12 mock treatment 1.04222549E8 500000.0 0.03 1.02269948E8 -192000.0 -0.01 0.0108 0.3913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H13 mock treatment 9.8177952E7 -5540000.0 -0.28 9.6887668E7 -5570000.0 -0.3 -0.4132 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H14 mock treatment 1.02565423E8 -1160000.0 -0.06 9.9066214E7 -3400000.0 -0.18 -0.1712 -0.8908 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H15 mock treatment 9.9314016E7 -4410000.0 -0.23 9.8179477E7 -4280000.0 -0.23 -0.3228 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H16 mock treatment 9.3921895E7 -9800000.0 -0.5 9.225497E7 -1.02E7 -0.55 -0.7438 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H17 mock treatment 9.9671736E7 -4050000.0 -0.21 9.4999994E7 -7460000.0 -0.4 -0.4309 -0.9528 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H18 mock treatment 9.6189667E7 -7530000.0 -0.39 9.5226129E7 -7240000.0 -0.39 -0.5485 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H19 mock treatment 9.9172883E7 -4550000.0 -0.23 9.762317E7 -4840000.0 -0.26 -0.3491 -0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H20 mock treatment 9.4991335E7 -8730000.0 -0.45 9.8243512E7 -4220000.0 -0.23 -0.4771 -0.9506 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H21 mock treatment 9.9280324E7 -4440000.0 -0.23 1.01469041E8 -993000.0 -0.05 -0.1988 -0.85 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H22 mock treatment 1.04946578E8 1220000.0 0.06 1.07338606E8 4880000.0 0.26 0.2301 0.852 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H23 mock treatment 1.09856589E8 6130000.0 0.31 1.10615433E8 8150000.0 0.44 0.5328 0.9866 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 H24 mock treatment 1.09997942E8 6280000.0 0.32 1.1969422E8 1.72E7 0.93 0.8836 0.8997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I01 compound treatment 1.21169097E8 1.74E7 0.89 1.24174754E8 2.17E7 1.17 1.4591 0.9912 DHPC8.2_000080 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I02 mock treatment 1.24223032E8 2.05E7 1.05 1.21764078E8 1.93E7 1.04 1.478 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I03 compound treatment 1.21913496E8 1.82E7 0.93 1.19429288E8 1.7E7 0.91 1.3053 0.9999 DHPC8.2_000081 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I04 mock treatment 1.18712806E8 1.5E7 0.77 1.15049358E8 1.26E7 0.68 1.0226 0.9981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I05 mock treatment 1.13363255E8 9640000.0 0.49 1.12145379E8 9680000.0 0.52 0.7181 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I06 mock treatment 1.0853943E8 4820000.0 0.25 1.08607987E8 6150000.0 0.33 0.4086 0.9896 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I07 compound treatment 1.15853557E8 1.21E7 0.62 1.0903011E8 6570000.0 0.35 0.6897 0.9643 DHPC8.2_000082 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I08 mock treatment 1.0725795E8 3540000.0 0.18 1.02731063E8 269000.0 0.01 0.1384 0.7613 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I09 compound treatment 9.8246417E7 -5480000.0 -0.28 9.5977454E7 -6480000.0 -0.35 -0.4454 -0.9941 DHPC8.2_000083 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I10 mock treatment 1.01698693E8 -2020000.0 -0.1 1.01768007E8 -694000.0 -0.04 -0.0998 -0.9049 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I11 compound treatment 1.04572951E8 850000.0 0.04 1.04075091E8 1610000.0 0.09 0.0922 0.9491 DHPC8.2_000084 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I12 mock treatment 1.04417413E8 695000.0 0.04 1.02485159E8 23400.0 0.0 0.0261 0.7316 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I13 compound treatment 9.67579E7 -6960000.0 -0.36 9.7863962E7 -4600000.0 -0.25 -0.4275 -0.984 DHPC8.2_000085 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I14 mock treatment 9.7850667E7 -5870000.0 -0.3 9.2982383E7 -9480000.0 -0.51 -0.5738 -0.9682 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I15 compound treatment 1.01558905E8 -2160000.0 -0.11 9.6869258E7 -5590000.0 -0.3 -0.2914 -0.9079 DHPC8.2_000086 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I16 mock treatment 9.1194339E7 -1.25E7 -0.64 9.103122E7 -1.14E7 -0.62 -0.8893 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I17 compound treatment 9.1291596E7 -1.24E7 -0.64 9.0389551E7 -1.21E7 -0.65 -0.9102 -0.9999 DHPC8.2_000087 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I18 mock treatment 9.5804489E7 -7920000.0 -0.41 9.1895844E7 -1.06E7 -0.57 -0.6893 -0.9863 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I19 compound treatment 9.6632714E7 -7090000.0 -0.36 9.6666311E7 -5800000.0 -0.31 -0.4776 -0.9971 DHPC8.2_000088 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I20 mock treatment 9.7782644E7 -5940000.0 -0.3 1.00972426E8 -1490000.0 -0.08 -0.272 -0.8639 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I21 mock treatment 9.7141646E7 -6580000.0 -0.34 1.00769001E8 -1690000.0 -0.09 -0.303 -0.8671 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I22 mock treatment 9.668049E7 -7040000.0 -0.36 9.7662218E7 -4800000.0 -0.26 -0.438 -0.9866 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I23 compound treatment 9.9686095E7 -4040000.0 -0.21 1.05363479E8 2900000.0 0.16 -0.0358 -0.1381 DHPC8.2_000089 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 I24 mock treatment 1.13125427E8 9400000.0 0.48 1.15014917E8 1.26E7 0.68 0.8188 0.9862 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J01 mock treatment 1.23600841E8 1.99E7 1.02 1.24160234E8 2.17E7 1.17 1.5466 0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J02 mock treatment 1.22843376E8 1.91E7 0.98 1.20377743E8 1.79E7 0.96 1.3752 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J03 mock treatment 1.16718999E8 1.3E7 0.67 1.172901E8 1.48E7 0.8 1.0356 0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J04 mock treatment 1.13629782E8 9910000.0 0.51 1.14455711E8 1.2E7 0.65 0.8158 0.9929 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J05 mock treatment 1.13219327E8 9500000.0 0.49 1.1323298E8 1.08E7 0.58 0.7543 0.9962 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J06 mock treatment 1.17155698E8 1.34E7 0.69 1.12063609E8 9600000.0 0.52 0.8524 0.99 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J07 mock treatment 1.06155089E8 2430000.0 0.12 1.02174139E8 -288000.0 -0.02 0.0772 0.6145 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J08 mock treatment 1.06923453E8 3200000.0 0.16 1.01404624E8 -1060000.0 -0.06 0.0757 0.4362 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J09 mock treatment 1.11503953E8 7780000.0 0.4 1.04805589E8 2340000.0 0.13 0.3712 0.8875 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J10 mock treatment 9.9859228E7 -3860000.0 -0.2 1.02544422E8 82600.0 0.0 -0.1369 -0.691 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J11 mock treatment 1.04198077E8 475000.0 0.02 1.01556835E8 -905000.0 -0.05 -0.0172 -0.3162 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J12 mock treatment 1.03851303E8 129000.0 0.01 9.6742903E7 -5720000.0 -0.31 -0.2131 -0.6918 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J13 mock treatment 9.671912E7 -7000000.0 -0.36 9.4145583E7 -8320000.0 -0.45 -0.5705 -0.994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J14 mock treatment 9.8377079E7 -5350000.0 -0.27 9.4920161E7 -7540000.0 -0.41 -0.4809 -0.9816 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J15 mock treatment 9.4933506E7 -8790000.0 -0.45 8.9378239E7 -1.31E7 -0.7 -0.8167 -0.9766 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J16 mock treatment 9.0640862E7 -1.31E7 -0.67 8.4973483E7 -1.75E7 -0.94 -1.14 -0.9861 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J17 mock treatment 9.0521173E7 -1.32E7 -0.68 8.8903527E7 -1.36E7 -0.73 -0.9947 -0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J18 mock treatment 9.1532713E7 -1.22E7 -0.62 8.6492666E7 -1.6E7 -0.86 -1.0499 -0.9877 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J19 mock treatment 9.4790612E7 -8930000.0 -0.46 9.1768778E7 -1.07E7 -0.58 -0.7309 -0.9935 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J20 mock treatment 9.7617832E7 -6100000.0 -0.31 9.9052955E7 -3410000.0 -0.18 -0.351 -0.9677 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J21 mock treatment 9.2974437E7 -1.07E7 -0.55 9.918113E7 -3280000.0 -0.18 -0.5144 -0.8893 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J22 mock treatment 9.7317504E7 -6410000.0 -0.33 9.9827771E7 -2630000.0 -0.14 -0.3324 -0.9296 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J23 mock treatment 1.15400038E8 1.17E7 0.6 1.12132434E8 9670000.0 0.52 0.7914 0.9976 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 J24 mock treatment 1.11414693E8 7690000.0 0.39 1.18304949E8 1.58E7 0.85 0.882 0.9385 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K01 compound treatment 1.18803957E8 1.51E7 0.77 1.2457727E8 2.21E7 1.19 1.3887 0.9781 DHPC8.2_000090 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K02 mock treatment 1.18045292E8 1.43E7 0.73 1.22955799E8 2.05E7 1.1 1.2994 0.9804 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K03 compound treatment 1.1251144E8 8790000.0 0.45 1.18508053E8 1.6E7 0.86 0.9295 0.9539 DHPC8.2_000091 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K04 mock treatment 1.14966955E8 1.12E7 0.58 1.17579213E8 1.51E7 0.81 0.9832 0.9857 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K05 compound treatment 1.15820129E8 1.21E7 0.62 1.1324379E8 1.08E7 0.58 0.849 0.9995 DHPC8.2_000092 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K06 mock treatment 1.07833995E8 4110000.0 0.21 1.04316093E8 1850000.0 0.1 0.2196 0.9418 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K07 mock treatment 1.05578046E8 1860000.0 0.1 1.07670114E8 5210000.0 0.28 0.2656 0.8967 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K08 mock treatment 1.03978056E8 255000.0 0.01 9.9886322E7 -2580000.0 -0.14 -0.0888 -0.6375 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K09 compound treatment 1.08314147E8 4590000.0 0.24 1.0360415E8 1140000.0 0.06 0.2099 0.863 DHPC8.2_000093 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K10 mock treatment 9.9862938E7 -3860000.0 -0.2 1.00141835E8 -2320000.0 -0.12 -0.2282 -0.9754 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K11 compound treatment 1.06658374E8 2940000.0 0.15 1.00694429E8 -1770000.0 -0.1 0.0391 0.2196 DHPC8.2_000094 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K12 mock treatment 9.5482335E7 -8240000.0 -0.42 9.3851986E7 -8610000.0 -0.46 -0.6265 -0.9989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K13 compound treatment 9.3700419E7 -1.0E7 -0.51 9.2204666E7 -1.03E7 -0.55 -0.7538 -0.9993 DHPC8.2_000095 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K14 mock treatment 9.6683263E7 -7040000.0 -0.36 9.0780642E7 -1.17E7 -0.63 -0.6999 -0.9652 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K15 mock treatment 9.078925E7 -1.29E7 -0.66 8.7901146E7 -1.46E7 -0.78 -1.0232 -0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K16 mock treatment 8.7168058E7 -1.66E7 -0.85 8.6633258E7 -1.58E7 -0.85 -1.2027 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K17 compound treatment 9.1827361E7 -1.19E7 -0.61 8.8952028E7 -1.35E7 -0.73 -0.9455 -0.9961 DHPC8.2_000096 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K18 mock treatment 9.2640691E7 -1.11E7 -0.57 8.6792939E7 -1.57E7 -0.84 -0.9983 -0.9814 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K19 compound treatment 9.2542492E7 -1.12E7 -0.57 9.074074E7 -1.17E7 -0.63 -0.8515 -0.9988 DHPC8.2_000097 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K20 mock treatment 9.6155962E7 -7570000.0 -0.39 9.8682296E7 -3780000.0 -0.2 -0.4181 -0.9547 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K21 compound treatment 9.469674E7 -9030000.0 -0.46 1.02004155E8 -458000.0 -0.02 -0.3445 -0.7437 DHPC8.2_000098 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K22 mock treatment 9.8662679E7 -5060000.0 -0.26 9.992107E7 -2540000.0 -0.14 -0.2801 -0.9554 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K23 mock treatment 9.5804128E7 -7920000.0 -0.41 1.02357301E8 -104000.0 -0.01 -0.291 -0.7168 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 K24 mock treatment 1.02275776E8 -1450000.0 -0.07 1.11278883E8 8820000.0 0.47 0.2833 0.5895 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L01 mock treatment 1.14806547E8 1.11E7 0.57 1.2698145E8 2.45E7 1.32 1.3354 0.929 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L02 mock treatment 1.09676527E8 5950000.0 0.31 1.12505507E8 1.0E7 0.54 0.5982 0.9633 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L03 mock treatment 1.16940512E8 1.32E7 0.68 1.15944546E8 1.35E7 0.73 0.9924 0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L04 mock treatment 1.09757738E8 6040000.0 0.31 1.12670187E8 1.02E7 0.55 0.6074 0.963 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L05 mock treatment 1.10577331E8 6850000.0 0.35 1.12173005E8 9710000.0 0.52 0.6182 0.9813 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L06 mock treatment 1.07199274E8 3480000.0 0.18 1.08936448E8 6470000.0 0.35 0.3725 0.9514 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L07 mock treatment 1.03955092E8 232000.0 0.01 1.02623464E8 162000.0 0.01 0.0146 0.9881 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L08 mock treatment 9.718285E7 -6540000.0 -0.34 9.8121508E7 -4340000.0 -0.23 -0.4023 -0.9845 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L09 mock treatment 9.745831E7 -6260000.0 -0.32 9.6622822E7 -5840000.0 -0.31 -0.4494 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L10 mock treatment 1.05973953E8 2250000.0 0.12 1.00926808E8 -1530000.0 -0.08 0.0231 0.163 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L11 mock treatment 9.511306E7 -8610000.0 -0.44 9.4947974E7 -7510000.0 -0.4 -0.5981 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L12 mock treatment 1.01276352E8 -2450000.0 -0.13 9.6348611E7 -6110000.0 -0.33 -0.3214 -0.9125 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L13 mock treatment 9.4524875E7 -9200000.0 -0.47 9.4927697E7 -7530000.0 -0.41 -0.6202 -0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L14 mock treatment 9.3916464E7 -9810000.0 -0.5 9.3235776E7 -9230000.0 -0.5 -0.7067 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L15 mock treatment 8.7272581E7 -1.65E7 -0.84 8.8053054E7 -1.44E7 -0.78 -1.1448 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L16 mock treatment 8.3611416E7 -2.01E7 -1.03 8.6609569E7 -1.59E7 -0.85 -1.3325 -0.9956 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L17 mock treatment 9.0320759E7 -1.34E7 -0.69 8.7596428E7 -1.49E7 -0.8 -1.0517 -0.9971 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L18 mock treatment 8.9264606E7 -1.45E7 -0.74 8.7624593E7 -1.48E7 -0.8 -1.089 -0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L19 mock treatment 9.1279097E7 -1.24E7 -0.64 9.2414739E7 -1.0E7 -0.54 -0.8335 -0.9967 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L20 mock treatment 1.01353434E8 -2370000.0 -0.12 9.9405543E7 -3060000.0 -0.16 -0.2022 -0.9888 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L21 mock treatment 9.4391427E7 -9330000.0 -0.48 9.9910133E7 -2550000.0 -0.14 -0.4353 -0.8749 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L22 mock treatment 9.7446565E7 -6280000.0 -0.32 9.9241464E7 -3220000.0 -0.17 -0.3501 -0.958 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L23 mock treatment 9.8081038E7 -5640000.0 -0.29 1.03380587E8 919000.0 0.05 -0.1695 -0.5777 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 L24 mock treatment 1.05499159E8 1780000.0 0.09 1.1160178E8 9140000.0 0.49 0.4124 0.8239 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M01 compound treatment 1.34092765E8 3.04E7 1.56 1.32143087E8 2.97E7 1.6 2.2309 0.9999 DHPC8.2_000099 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M02 mock treatment 1.1235844E8 8640000.0 0.44 1.18513895E8 1.61E7 0.86 0.9242 0.9517 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M03 compound treatment 1.13992777E8 1.03E7 0.53 1.12091534E8 9630000.0 0.52 0.7389 1.0 DHPC8.2_000100 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M04 mock treatment 1.11025355E8 7300000.0 0.37 1.15886385E8 1.34E7 0.72 0.7758 0.953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M05 compound treatment 1.04839118E8 1120000.0 0.06 1.07545166E8 5080000.0 0.27 0.234 0.8368 DHPC8.2_000101 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M06 mock treatment 1.10270518E8 6550000.0 0.34 1.07762516E8 5300000.0 0.29 0.4391 0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M07 compound treatment 1.00141437E8 -3580000.0 -0.18 9.5741038E7 -6720000.0 -0.36 -0.3857 -0.9505 DHPC8.2_000102 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M08 mock treatment 1.09213E8 5490000.0 0.28 1.03937866E8 1480000.0 0.08 0.2552 0.8727 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M09 mock treatment 9.4940728E7 -8780000.0 -0.45 9.4404216E7 -8060000.0 -0.43 -0.6251 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M10 mock treatment 9.3199785E7 -1.05E7 -0.54 9.1185572E7 -1.13E7 -0.61 -0.8107 -0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M11 compound treatment 8.7730301E7 -1.6E7 -0.82 9.2200464E7 -1.03E7 -0.55 -0.9703 -0.9816 DHPC8.2_000103 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M12 mock treatment 9.249107E7 -1.12E7 -0.58 9.0886521E7 -1.16E7 -0.62 -0.8478 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M13 mock treatment 9.2550076E7 -1.12E7 -0.57 9.2501269E7 -9960000.0 -0.54 -0.7842 -0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M14 mock treatment 9.2266406E7 -1.15E7 -0.59 8.9683158E7 -1.28E7 -0.69 -0.9018 -0.9969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M15 compound treatment 7.9148023E7 -2.46E7 -1.26 8.34008E7 -1.91E7 -1.03 -1.6164 -0.9948 DHPC8.2_000104 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M16 mock treatment 7.9467586E7 -2.43E7 -1.24 8.1224892E7 -2.12E7 -1.14 -1.6877 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M17 compound treatment 7.6573748E7 -2.71E7 -1.39 8.5797607E7 -1.67E7 -0.9 -1.6184 -0.9775 DHPC8.2_000105 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M18 mock treatment 8.3943616E7 -1.98E7 -1.01 9.0300558E7 -1.22E7 -0.65 -1.1799 -0.9776 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M19 compound treatment 8.6496839E7 -1.72E7 -0.88 9.215027E7 -1.03E7 -0.56 -1.0169 -0.975 DHPC8.2_000106 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M20 mock treatment 8.7379508E7 -1.63E7 -0.84 9.503834E7 -7420000.0 -0.4 -0.875 -0.9427 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M21 compound treatment 1.00944213E8 -2780000.0 -0.14 1.02000459E8 -461000.0 -0.02 -0.1183 -0.8181 DHPC8.2_000107 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M22 mock treatment 9.5492176E7 -8230000.0 -0.42 1.04917783E8 2460000.0 0.13 -0.2048 -0.4632 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M23 compound treatment 1.06202162E8 2480000.0 0.13 1.03250373E8 789000.0 0.04 0.1199 0.8948 DHPC8.2_000108 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 M24 mock treatment 1.0836474E8 4640000.0 0.24 1.03317845E8 856000.0 0.05 0.2008 0.8287 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N01 mock treatment 1.17305911E8 1.36E7 0.7 1.15330086E8 1.29E7 0.69 0.9823 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N02 mock treatment 1.23817515E8 2.01E7 1.03 1.24145067E8 2.17E7 1.17 1.5539 0.998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N03 mock treatment 1.12208003E8 8490000.0 0.43 1.18122788E8 1.57E7 0.84 0.9039 0.9525 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N04 mock treatment 1.11501291E8 7780000.0 0.4 1.15292938E8 1.28E7 0.69 0.7705 0.9659 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N05 mock treatment 1.09133965E8 5410000.0 0.28 1.13750638E8 1.13E7 0.61 0.626 0.9368 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N06 mock treatment 1.07707376E8 3980000.0 0.2 1.04250602E8 1790000.0 0.1 0.2125 0.9412 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N07 mock treatment 9.6569558E7 -7150000.0 -0.37 1.04011084E8 1550000.0 0.08 -0.2002 -0.5326 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N08 mock treatment 9.1062531E7 -1.27E7 -0.65 9.9610073E7 -2850000.0 -0.15 -0.5674 -0.851 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N09 mock treatment 9.3566358E7 -1.02E7 -0.52 9.6772598E7 -5690000.0 -0.31 -0.5847 -0.9681 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N10 mock treatment 8.9346539E7 -1.44E7 -0.74 8.8171201E7 -1.43E7 -0.77 -1.0652 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N11 mock treatment 8.9076563E7 -1.46E7 -0.75 9.2563031E7 -9900000.0 -0.53 -0.9077 -0.9859 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N12 mock treatment 9.6755777E7 -6970000.0 -0.36 9.4385436E7 -8080000.0 -0.43 -0.56 -0.9952 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N13 mock treatment 8.6850834E7 -1.69E7 -0.86 8.5821498E7 -1.66E7 -0.9 -1.2451 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N14 mock treatment 8.394233E7 -1.98E7 -1.01 8.2078909E7 -2.04E7 -1.1 -1.493 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N15 mock treatment 8.2798879E7 -2.09E7 -1.07 8.3761142E7 -1.87E7 -1.01 -1.4704 -0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N16 mock treatment 8.5585061E7 -1.81E7 -0.93 7.5752894E7 -2.67E7 -1.44 -1.6744 -0.9777 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N17 mock treatment 7.6705438E7 -2.7E7 -1.38 8.3953882E7 -1.85E7 -1.0 -1.6839 -0.987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N18 mock treatment 7.8783184E7 -2.49E7 -1.28 8.8853457E7 -1.36E7 -0.73 -1.422 -0.9651 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N19 mock treatment 8.7676357E7 -1.6E7 -0.82 9.4237938E7 -8220000.0 -0.44 -0.8947 -0.9578 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N20 mock treatment 1.0132978E8 -2390000.0 -0.12 1.00251679E8 -2210000.0 -0.12 -0.1709 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N21 mock treatment 9.0861077E7 -1.29E7 -0.66 9.4122957E7 -8340000.0 -0.45 -0.7836 -0.9825 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N22 mock treatment 9.2087317E7 -1.16E7 -0.6 1.04869459E8 2410000.0 0.13 -0.33 -0.5407 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N23 mock treatment 1.03760757E8 38100.0 0.0 9.5586701E7 -6880000.0 -0.37 -0.2604 -0.7034 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 N24 mock treatment 1.12444748E8 8720000.0 0.45 1.06779848E8 4320000.0 0.23 0.4805 0.9536 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O01 compound treatment 1.25818592E8 2.21E7 1.13 1.25447146E8 2.3E7 1.24 1.676 0.999 DHPC8.2_000109 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O02 mock treatment 1.12964372E8 9240000.0 0.47 1.1299288E8 1.05E7 0.57 0.7359 0.996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O03 compound treatment 1.08719458E8 5000000.0 0.26 1.04653436E8 2190000.0 0.12 0.2645 0.9381 DHPC8.2_000110 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O04 mock treatment 1.02410196E8 -1310000.0 -0.07 1.18982466E8 1.65E7 0.89 0.5815 0.6518 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O05 compound treatment 1.08334355E8 4610000.0 0.24 1.08179429E8 5720000.0 0.31 0.3849 0.9915 DHPC8.2_000111 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O06 mock treatment 9.684401E7 -6880000.0 -0.35 1.02968893E8 507000.0 0.03 -0.23 -0.6504 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O07 compound treatment 9.078349E7 -1.29E7 -0.66 9.9062605E7 -3400000.0 -0.18 -0.5984 -0.8698 DHPC8.2_000112 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O08 mock treatment 8.978492E7 -1.39E7 -0.71 9.8616523E7 -3850000.0 -0.21 -0.6515 -0.876 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O09 compound treatment 8.9320406E7 -1.44E7 -0.74 9.8457452E7 -4000000.0 -0.22 -0.6744 -0.877 DHPC8.2_000113 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O10 mock treatment 9.3415303E7 -1.03E7 -0.53 9.729093E7 -5170000.0 -0.28 -0.5704 -0.9552 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O11 mock treatment 8.9897909E7 -1.38E7 -0.71 9.5973325E7 -6490000.0 -0.35 -0.7481 -0.9469 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O12 mock treatment 9.280213E7 -1.09E7 -0.56 9.3753637E7 -8710000.0 -0.47 -0.7274 -0.9961 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O13 compound treatment 9.2056739E7 -1.17E7 -0.6 8.0994187E7 -2.15E7 -1.16 -1.2402 -0.9529 DHPC8.2_000114 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O14 mock treatment 9.3905926E7 -9820000.0 -0.5 9.3995416E7 -8470000.0 -0.46 -0.6782 -0.9988 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O15 compound treatment 8.102378E7 -2.27E7 -1.16 9.0547069E7 -1.19E7 -0.64 -1.2763 -0.9607 DHPC8.2_000115 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O16 mock treatment 8.2307858E7 -2.14E7 -1.1 8.0605542E7 -2.19E7 -1.18 -1.6083 -0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O17 compound treatment 8.3302828E7 -2.04E7 -1.05 8.4582684E7 -1.79E7 -0.96 -1.4208 -0.9991 DHPC8.2_000116 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O18 mock treatment 8.0351643E7 -2.34E7 -1.2 9.1462583E7 -1.1E7 -0.59 -1.2658 -0.9473 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O19 compound treatment 8.3189569E7 -2.05E7 -1.05 8.3765994E7 -1.87E7 -1.01 -1.456 -0.9998 DHPC8.2_000117 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O20 mock treatment 8.4881884E7 -1.88E7 -0.97 8.6833179E7 -1.56E7 -0.84 -1.2779 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O21 compound treatment 1.08455445E8 4730000.0 0.24 1.09044782E8 6580000.0 0.35 0.4222 0.9829 DHPC8.2_000118 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O22 mock treatment 1.00826831E8 -2900000.0 -0.15 9.8453825E7 -4010000.0 -0.22 -0.2576 -0.9833 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O23 compound treatment 1.03007739E8 -715000.0 -0.04 9.7955589E7 -4510000.0 -0.24 -0.1975 -0.8048 DHPC8.2_000119 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 O24 mock treatment 1.21111469E8 1.74E7 0.89 1.18183559E8 1.57E7 0.85 1.2288 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P01 mock treatment 1.31433125E8 2.77E7 1.42 1.21532259E8 1.91E7 1.03 1.7304 0.9873 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P02 mock treatment 1.19960794E8 1.62E7 0.83 1.1486618E8 1.24E7 0.67 1.0608 0.9941 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P03 mock treatment 1.13003909E8 9280000.0 0.48 1.11004851E8 8540000.0 0.46 0.6617 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P04 mock treatment 1.06780594E8 3060000.0 0.16 1.06002829E8 3540000.0 0.19 0.2457 0.9953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P05 mock treatment 9.7332631E7 -6390000.0 -0.33 9.7157096E7 -5300000.0 -0.29 -0.4336 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P06 mock treatment 1.0306868E8 -654000.0 -0.03 1.03777249E8 1320000.0 0.07 0.0264 0.3367 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P07 mock treatment 9.1945714E7 -1.18E7 -0.6 1.00193769E8 -2270000.0 -0.12 -0.5132 -0.8333 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P08 mock treatment 9.1428784E7 -1.23E7 -0.63 8.5850074E7 -1.66E7 -0.89 -1.0781 -0.9853 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P09 mock treatment 1.0658498E8 2860000.0 0.15 9.1653075E7 -1.08E7 -0.58 -0.3078 -0.5129 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P10 mock treatment 9.5915856E7 -7810000.0 -0.4 8.9320199E7 -1.31E7 -0.71 -0.7833 -0.9636 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P11 mock treatment 9.3035928E7 -1.07E7 -0.55 9.7131553E7 -5330000.0 -0.29 -0.5903 -0.9545 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P12 mock treatment 1.06034037E8 2310000.0 0.12 8.8444286E7 -1.4E7 -0.75 -0.45 -0.5889 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P13 mock treatment 9.4670617E7 -9050000.0 -0.46 8.9490644E7 -1.3E7 -0.7 -0.822 -0.9802 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P14 mock treatment 9.2991836E7 -1.07E7 -0.55 8.2602922E7 -1.99E7 -1.07 -1.1451 -0.9522 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P15 mock treatment 9.1210711E7 -1.25E7 -0.64 7.9214286E7 -2.32E7 -1.25 -1.3387 -0.9517 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P16 mock treatment 8.891128E7 -1.48E7 -0.76 7.4460523E7 -2.8E7 -1.51 -1.603 -0.9495 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P17 mock treatment 9.0643081E7 -1.31E7 -0.67 8.1675422E7 -2.08E7 -1.12 -1.2655 -0.9699 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P18 mock treatment 9.2239949E7 -1.15E7 -0.59 8.8894754E7 -1.36E7 -0.73 -0.9328 -0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P19 mock treatment 9.4316743E7 -9410000.0 -0.48 8.898809E7 -1.35E7 -0.73 -0.8539 -0.9803 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P20 mock treatment 9.6663528E7 -7060000.0 -0.36 9.1548181E7 -1.09E7 -0.59 -0.6714 -0.9728 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P21 mock treatment 1.11165641E8 7440000.0 0.38 9.2512011E7 -9950000.0 -0.54 -0.1091 -0.1659 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P22 mock treatment 1.04077224E8 355000.0 0.02 9.5649254E7 -6810000.0 -0.37 -0.2466 -0.6713 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P23 mock treatment 1.21125596E8 1.74E7 0.89 1.07430618E8 4970000.0 0.27 0.8199 0.8805 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2412 P24 mock treatment 1.24922063E8 2.12E7 1.09 1.12971117E8 1.05E7 0.57 1.1685 0.9538 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A01 compound treatment 1.31832925E8 3.41E7 1.75 1.25790621E8 2.97E7 1.6 2.3692 0.999 3635123 CMLD5_000001 COC(=O)c1nnc(C(=O)N(C)Cc2ccccc2)c3[nH]c4ccccc4c13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A02 compound treatment 1.24232217E8 2.65E7 1.36 1.17356852E8 2.13E7 1.15 1.7726 0.9965 3635124 CMLD5_000002 COCC1=Cc2cc3OCOc3cc2C(C(C(=O)OC)C(=O)OC)N1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A03 compound treatment 1.20868175E8 2.32E7 1.19 1.11504821E8 1.55E7 0.83 1.4278 0.985 3635125 CMLD5_000003 COC(=O)[C@@H](O)CC[C@@H](C)Cc1c(OC)c(OC)c(C)c(OC)c1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A04 compound treatment 1.31155356E8 3.34E7 1.71 1.22381213E8 2.63E7 1.42 2.2148 0.9956 3635127 CMLD5_000004 COC[C@H]1OC=C[C@@H](OC)[C@@H]1OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A05 compound treatment 1.14909361E8 1.72E7 0.88 1.06385568E8 1.03E7 0.56 1.0169 0.9755 3635129 CMLD5_000005 COC(=O)c1ccccc1C[C@@]2(C=C[C@H](C)[C@H](N2C(=O)C(F)(F)F)c3ccccc3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A06 compound treatment 1.13359726E8 1.56E7 0.8 1.00275009E8 4230000.0 0.23 0.7281 0.8735 3635131 CMLD5_000006 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@@H](NC(=O)OCC=C)c2ccc3OCOc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A07 compound treatment 1.07481118E8 9760000.0 0.5 9.6298492E7 256000.0 0.01 0.3636 0.7263 3635133 CMLD5_000007 COC(=O)c1nnc(SC)nc1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A08 compound treatment 1.16058618E8 1.83E7 0.94 1.08922564E8 1.29E7 0.69 1.1552 0.9888 3635134 CMLD5_000008 OP1(=O)Oc2c(cc3ccccc3c2-c4c(O1)c(cc5ccccc45)c6ccccc6)c7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A09 compound treatment 2.7685278E7 -7.0E7 -3.59 2.6672018E7 -6.94E7 -3.74 -5.1795 -0.9998 3635135 CMLD5_000009 CC(=O)O[C@@H]1C(=C(Br)C(=O)[C@@H]2O[C@@]21C)CO[Si](C)(C)C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A10 compound treatment 1.1690826E8 1.92E7 0.98 1.03637882E8 7600000.0 0.41 0.9847 0.9244 3635137 CMLD5_000010 C[C@H](O)CON1C(=O)c2ccccc2C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A11 compound treatment 1.06233504E8 8520000.0 0.44 1.00813602E8 4770000.0 0.26 0.4903 0.9681 3011273 CMLD5_000011 C=CC(=O)N1C(=O)c2ccccc2S1(=O)=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A12 compound treatment 4.6871641E7 -5.08E7 -2.61 4.3640825E7 -5.24E7 -2.82 -3.838 -0.9992 3556134 CMLD5_000012 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A13 mock treatment 1.21077058E8 2.34E7 1.2 1.18202624E8 2.22E7 1.19 1.6904 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A14 mock treatment 1.10215252E8 1.25E7 0.64 1.0370975E8 7670000.0 0.41 0.7449 0.9774 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A15 compound treatment 1.08914464E8 1.12E7 0.57 1.0062459E8 4580000.0 0.25 0.5803 0.9289 3635138 CMLD5_000013 COC(=O)N[C@@H](c1ccccc1)[C@](CC=C)(C(=O)C)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A16 compound treatment 1.16329201E8 1.86E7 0.95 1.08225603E8 1.22E7 0.66 1.1385 0.9833 3635140 CMLD5_000014 C[C@@H](O)C#C[Si](C)(C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A17 compound treatment 1.08911742E8 1.12E7 0.57 1.04422551E8 8380000.0 0.45 0.7248 0.9929 3635142 CMLD5_000015 COc1ccc(cc1)C(C)(O)CC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A18 compound treatment 1.10976765E8 1.33E7 0.68 1.022758E8 6230000.0 0.34 0.7179 0.9471 3635143 CMLD5_000016 COC(=O)N[C@@H](/C=C/c1ccccc1)/C(=C(\C)/NCc2ccccc2)/C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A19 compound treatment 9.8107399E7 390000.0 0.02 9.511027E7 -932000.0 -0.05 -0.0213 -0.3949 3635145 CMLD5_000017 CCOC(=O)C(CC=C)Nc1ccc(OC)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A20 compound treatment 1.14863455E8 1.71E7 0.88 1.07889781E8 1.18E7 0.64 1.0725 0.9876 3635146 CMLD5_000018 COC(=O)N[C@H](C[N+](=O)[O-])C(C)(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A21 compound treatment 5.2843776E7 -4.49E7 -2.3 5.4551849E7 -4.15E7 -2.23 -3.2061 -0.9999 3635148 CMLD5_000019 OC(CC=C)(C#Cc1ccccc1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A22 compound treatment 9.6286192E7 -1430000.0 -0.07 8.9573862E7 -6470000.0 -0.35 -0.2982 -0.8376 3635149 CMLD5_000020 O=C(/C=C/c1ccc2OCOc2c1)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A23 compound treatment 1.164792E8 1.88E7 0.96 1.09257734E8 1.32E7 0.71 1.1832 0.989 3635150 CMLD5_000021 Cc1ccc(/C=C/C2=C[C@]3(C)C[C@]2(C)[C@@H](CC3=O)c4ccc(C)cc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 A24 compound treatment 1.23347744E8 2.56E7 1.31 1.17919787E8 2.19E7 1.18 1.762 0.9985 3635152 CMLD5_000022 COC(=O)C1(CC2=CC[C@@H]3[C@H]([C@@H]2Cc4ccccc4[C@@H]1C[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B01 compound treatment 1.35515704E8 3.78E7 1.94 1.28167915E8 3.21E7 1.73 2.5932 0.9984 3635154 CMLD5_000023 COC(=O)c1nnc(C(=O)NCc2ccccc2)c3[nH]c4ccccc4c13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B02 compound treatment 1.18386546E8 2.07E7 1.06 1.08898051E8 1.29E7 0.69 1.2386 0.9787 3635155 CMLD5_000024 COC(=O)N1[C@H]2CC[C@@]3(C)C=C(C)O[C@]1(C)C3c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B03 compound treatment 1.07817064E8 1.01E7 0.52 1.00448805E8 4410000.0 0.24 0.5338 0.9374 3635157 CMLD5_000025 C[C@H]1CC[C@@H]2N(C[C@@H](COCC=C)OC2=O)[C@@H]1c3ccc(Br)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B04 compound treatment 8.7608998E7 -1.01E7 -0.52 7.3297522E7 -2.27E7 -1.22 -1.2324 -0.9267 3635158 CMLD5_000026 CC(C)OC(=O)[C@@H]1CC[C@H](C)[C@@H](CCC[C@@H]2CC=C[C@H](COS(=O)(=O)c3c(C)cc(C)cc3C)O2)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B05 compound treatment 8.4459994E7 -1.33E7 -0.68 7.7324786E7 -1.87E7 -1.01 -1.1932 -0.9816 3635160 CMLD5_000027 COC(=O)C(=C)C[C@]1(C[C@]2(CC=C(C)C)C(=C(C(=O)CC(C)C)C(=O)C(CC=C(C)C)(C1)C2=O)O)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B06 compound treatment 1.00214797E8 2500000.0 0.13 9.1199397E7 -4840000.0 -0.26 -0.0939 -0.3231 3635162 CMLD5_000028 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@@H](NC(=O)OCC=C)c2cccc(OC)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B07 compound treatment 1.02419444E8 4700000.0 0.24 9.7628661E7 1590000.0 0.09 0.2308 0.9027 3635164 CMLD5_000029 CC(=O)C([C@H](NC(=O)OCC=C)c1ccco1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B08 compound treatment 2.6939429E7 -7.08E7 -3.63 2.5712156E7 -7.03E7 -3.79 -5.2431 -0.9998 3635166 CMLD5_000030 COC(=O)C(=Cc1cc(Br)c(OC)c(Br)c1)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B09 compound treatment 2.6286834E7 -7.14E7 -3.66 2.5490691E7 -7.06E7 -3.8 -5.2752 -0.9998 3635167 CMLD5_000031 OCC1=C(Br)C2(OCCCO2)C=CC1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B10 compound treatment 9.1030601E7 -6690000.0 -0.34 8.5342857E7 -1.07E7 -0.58 -0.6497 -0.9692 3635168 CMLD5_000032 C[C@@H]1C[C@@](C)(C=C1c2ccc3OCOc3c2)C(=O)c4ccc5OCOc5c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B11 compound treatment 3.0211243E7 -6.75E7 -3.46 2.6386455E7 -6.97E7 -3.75 -5.0989 -0.9992 3635170 CMLD5_000033 COCOc1cc(OC)ccc1C(=O)/C=C/c2cccc(c2)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B12 compound treatment 5.6349998E7 -4.14E7 -2.12 5.5908398E7 -4.01E7 -2.16 -3.0274 -1.0 3635172 CMLD5_000034 COCOc1ccc(OC)cc1C(=O)[C@@H]2O[C@H]2c3ccc(OC)c(Br)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B13 mock treatment 1.02311466E8 4590000.0 0.24 9.4406734E7 -1640000.0 -0.09 0.1042 0.4146 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B14 mock treatment 1.02898922E8 5180000.0 0.27 9.2116232E7 -3930000.0 -0.21 0.0383 0.1128 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B15 compound treatment 9.2648799E7 -5070000.0 -0.26 9.1507269E7 -4530000.0 -0.24 -0.3564 -0.9995 3635174 CMLD5_000035 COC(=O)NC(C(=C)C(=O)OC)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B16 compound treatment 9.9963379E7 2250000.0 0.12 9.1547319E7 -4490000.0 -0.24 -0.0897 -0.3348 3635175 CMLD5_000036 CC(O)(CC=C)c1ccsc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B17 compound treatment 9.814551E7 429000.0 0.02 7.4026094E7 -2.2E7 -1.19 -0.8228 -0.6939 3635176 CMLD5_000037 FC(F)(F)c1cc(NC(=S)Nc2ccc3cc4ccccc4cc3c2)cc(c1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B18 compound treatment 9.3724377E7 -3990000.0 -0.2 8.1094435E7 -1.49E7 -0.8 -0.7139 -0.8595 3635177 CMLD5_000038 C[C@H](C=C)[C@](C)(O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B19 compound treatment 8.4123288E7 -1.36E7 -0.7 6.7896936E7 -2.81E7 -1.52 -1.5644 -0.9378 3635179 CMLD5_000039 C[C@@H]1C[C@@](C)(C=C1c2ccco2)C(=O)c3ccco3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B20 compound treatment 1.10325054E8 1.26E7 0.65 1.07243477E8 1.12E7 0.6 0.8835 0.9994 3635181 CMLD5_000040 COC(=O)NC(c1ccccc1)C2(C(=O)OC)C(=O)Cc3ccccc32 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B21 compound treatment 9.0680564E7 -7040000.0 -0.36 8.3246106E7 -1.28E7 -0.69 -0.7423 -0.9544 3635182 CMLD5_000041 COC(=O)N[C@@H](CCc1ccccc1)/C(=C(\C)/NCc2ccccc2)/C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B22 compound treatment 1.07203823E8 9490000.0 0.49 9.9483356E7 3440000.0 0.19 0.4748 0.9126 3635184 CMLD5_000042 O=C(NCc1ccccc1)/C=C/c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B23 compound treatment 5.8887545E7 -3.88E7 -1.99 6.0208202E7 -3.58E7 -1.93 -2.7717 -0.9999 3556292 CMLD5_000043 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 B24 compound treatment 9.0950977E7 -6770000.0 -0.35 7.0599369E7 -2.54E7 -1.37 -1.214 -0.859 3635186 CMLD5_000044 COCC(=C)C1=CCC([C@@H](C[N+](=O)[O-])c2ccccc12)(C(=O)OC)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C01 compound treatment 1.15956161E8 1.82E7 0.93 1.01586825E8 5540000.0 0.3 0.8721 0.8887 3635188 CMLD5_000045 O=C(NCC1CCCCC1)c2nnc(C(=O)NCC3CCCCC3)c4c5ccccc5[nH]c24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C02 compound treatment 1.06986847E8 9270000.0 0.48 9.7766848E7 1720000.0 0.09 0.4016 0.8296 3635189 CMLD5_000046 COC(=O)CC1N(C(=O)OC)C(=Cc2ccccc12)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C03 compound treatment 7.9804124E7 -1.79E7 -0.92 7.2597517E7 -2.34E7 -1.26 -1.5419 -0.9878 3635190 CMLD5_000047 COC(=O)[C@H]1O[C@H]([C@H](C)[C@H]2O[C@]21C)c3cc(OC)c(C)c(OC)c3OCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C04 compound treatment 1.06698144E8 8980000.0 0.46 9.851672E7 2470000.0 0.13 0.4197 0.8758 3635192 CMLD5_000048 CC(C)OC(=O)[C@@H]1CC[C@H](C)[C@@H](CCCC=O)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C05 compound treatment 7.7176578E7 -2.05E7 -1.05 6.2137718E7 -3.39E7 -1.83 -2.0354 -0.9658 3635194 CMLD5_000049 COC1=C(C(=O)c2ccccc2)C(=O)[C@]3(CC=C(C)C)C(=O)C1(CC=C(C)C)C[C@H](CCCC(F)(F)F)C3(C)C.COC1=C(C(=O)c2ccccc2)C(=O)C3(CC=C(C)C)C[C@H](C(=O)OCC(F)(F)F)C(C)(C)[C@@]1(CC=C(C)C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C06 compound treatment 1.01839806E8 4120000.0 0.21 9.9310523E7 3270000.0 0.18 0.2739 0.9959 2102645 CMLD5_000050 CSc1nnc(SC)nn1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C07 compound treatment 9.0092136E7 -7620000.0 -0.39 9.1130301E7 -4910000.0 -0.26 -0.4634 -0.9819 3635196 CMLD5_000051 COC(=O)C/C=C/[C@@H](C)[C@H](NC(=O)OCC(Cl)(Cl)Cl)c1ccc2ccccc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C08 compound treatment 9.7658892E7 -58000.0 0.0 9.6108753E7 66600.0 0.0 4.0E-4 0.0926 3635198 CMLD5_000052 CC1(C)O[C@@H]2[C@@H](O1)C(OP(=O)(O)OC2(c3ccccc3)c4ccccc4)(c5ccccc5)c6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C09 compound treatment 1.06158229E8 8440000.0 0.43 9.8690291E7 2650000.0 0.14 0.4068 0.8929 3635200 CMLD5_000053 COC(=O)c1nnc(C(=O)NCc2ccccc2)c3[nH]c4ccc(OC)cc4c13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C10 compound treatment 1.01114473E8 3400000.0 0.17 1.01126141E8 5080000.0 0.27 0.3167 0.9761 3635201 CMLD5_000054 CC(=C)C(=O)c1ccc(F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C11 mock treatment 1.05199904E8 7480000.0 0.38 1.04402061E8 8360000.0 0.45 0.5895 0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C12 mock treatment 1.04366551E8 6650000.0 0.34 1.04957668E8 8920000.0 0.48 0.5805 0.9859 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C13 compound treatment 9.8671306E7 954000.0 0.05 1.02926655E8 6880000.0 0.37 0.2967 0.7935 1060776 CMLD5_000055 COC(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C14 compound treatment 2.7166027E7 -7.06E7 -3.62 2.6175921E7 -6.99E7 -3.76 -5.2172 -0.9998 3635202 CMLD5_000056 COC(=O)C(C(NC(=O)OCC=C)c1ccc(F)c(F)c1)C(=O)CCl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C15 mock treatment 9.9439751E7 1720000.0 0.09 9.6322704E7 281000.0 0.02 0.0731 0.8162 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C16 mock treatment 9.5785078E7 -1930000.0 -0.1 9.2546756E7 -3500000.0 -0.19 -0.2031 -0.955 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C17 compound treatment 4.3498255E7 -5.42E7 -2.78 3.8716645E7 -5.73E7 -3.09 -4.1478 -0.9986 3635203 CMLD5_000057 FC(F)(F)c1cc(NC(=S)NC2(CC3CC4CC(C3)C2)C4)cc(c1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C18 compound treatment 9.6377298E7 -1340000.0 -0.07 9.0609831E7 -5430000.0 -0.29 -0.2554 -0.85 3635204 CMLD5_000058 COCC(=O)C([C@H](CCc1ccccc1)NC(=O)OC)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C19 compound treatment 9.4888006E7 -2830000.0 -0.14 9.1438064E7 -4600000.0 -0.25 -0.2778 -0.9673 3635206 CMLD5_000059 CCOP(=O)(CC(=O)C(=C)C)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C20 compound treatment 9.7538253E7 -179000.0 -0.01 9.3952918E7 -2090000.0 -0.11 -0.086 -0.7621 3635207 CMLD5_000060 COC(=O)C1(C)C=C(Nc2ccc(OC)cc2)C(=O)N1c3ccc(OC)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C21 compound treatment 9.9512931E7 1800000.0 0.09 9.412425E7 -1920000.0 -0.1 -0.0079 -0.0574 3635208 CMLD5_000061 OC(C1=CCCC1=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C22 compound treatment 4.3200904E7 -5.45E7 -2.79 3.9586827E7 -5.65E7 -3.04 -4.1254 -0.9991 3635209 CMLD5_000062 Nc1ccccc1C(=O)/C=C/c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C23 compound treatment 2.7208979E7 -7.05E7 -3.61 2.6595068E7 -6.94E7 -3.74 -5.1997 -0.9999 3635211 CMLD5_000063 C[Si](C)(C/C=C/CC[C@H](O)C1=CCCCC1=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 C24 compound treatment 1.22590136E8 2.49E7 1.27 1.168577E8 2.08E7 1.12 1.6941 0.9979 3635213 CMLD5_000064 COCC1=C2[C@H](CC3([C@@H](CNC3=O)c4ccccc24)C(=O)OC)n5n(C1)c(=O)n(c6ccccc6)c5=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D01 compound treatment 1.12270453E8 1.46E7 0.75 1.00831478E8 4790000.0 0.26 0.7098 0.8994 3635215 CMLD5_000065 COC(=O)C1(CC2=CC(CC2=O)Cc3ccccc3[C@@H]1C[N+](=O)[O-])C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D02 compound treatment 1.00040991E8 2320000.0 0.12 9.2804713E7 -3240000.0 -0.17 -0.0391 -0.1849 3635217 CMLD5_000066 COC(=O)N1C(c2ccccc2C=C1c3ccccc3)C4(CCCC4=O)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D03 compound treatment 1.00261057E8 2540000.0 0.13 1.08899851E8 1.29E7 0.69 0.5818 0.8258 3635218 CMLD5_000067 COC[C@H]1O[C@H]([C@H](OC)[C@@H](OC)[C@@H]1OC)c2c(OC)cc(OC)cc2OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D04 compound treatment 9.8690864E7 974000.0 0.05 9.8053859E7 2010000.0 0.11 0.1119 0.9381 3635220 CMLD5_000068 CC(C)OC(=O)[C@@H]1CC[C@H](C)[C@@H](CCC[C@@H]2C[C@@H](O)C[C@H](CC#N)O2)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D05 compound treatment 9.9136748E7 1420000.0 0.07 9.8669573E7 2630000.0 0.14 0.1515 0.9522 3635222 CMLD5_000069 COC(=O)[C@H]1CC2(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C(=O)C(=C2OC)C(=O)c3ccccc3)C1(C)C.COC1=C(C(=O)c2ccccc2)C(=O)C3(CC=C(C)C)C[C@H](C(=O)O)C(C)(C)[C@@]1(CC=C(C)C)C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D06 compound treatment 1.07832369E8 1.01E7 0.52 1.04770079E8 8730000.0 0.47 0.6989 0.9988 3635224 CMLD5_000070 CC(=O)C([C@H](NC(=O)OCC=C)c1ccccc1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D07 compound treatment 1.02272871E8 4560000.0 0.23 9.7893803E7 1850000.0 0.1 0.2356 0.928 3635226 CMLD5_000071 Cc1ccc(cc1)S(=O)(=O)N(c2ccccc2)S(=O)(=O)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D08 compound treatment 9.4929951E7 -2790000.0 -0.14 9.4712013E7 -1330000.0 -0.07 -0.1517 -0.9491 3635227 CMLD5_000072 OP1(=O)Oc2c(c(cc3ccccc23)c4ccccc4)-c5c(cc6ccccc6c5O1)c7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D09 compound treatment 8.1935829E7 -1.58E7 -0.81 8.699908E7 -9040000.0 -0.49 -0.9163 -0.9705 3635228 CMLD5_000073 COC(=O)C12CC3=CC(CC3=O)Cc4ccccc4[C@@H]2CNC1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D10 compound treatment 2.622334E7 -7.15E7 -3.66 2.5452699E7 -7.06E7 -3.8 -5.2789 -0.9998 3635230 CMLD5_000074 CC(=C)C(=O)/C=C/c1ccc(Br)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D11 mock treatment 9.4931973E7 -2780000.0 -0.14 9.7556306E7 1510000.0 0.08 -0.0433 -0.2633 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D12 mock treatment 1.04597746E8 6880000.0 0.35 1.02599549E8 6560000.0 0.35 0.4991 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D13 compound treatment 9.6827337E7 -890000.0 -0.05 9.7992134E7 1950000.0 0.11 0.042 0.367 3635232 CMLD5_000075 C/C=C(\C)/[C@H](O)C[Si](C)(C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D14 compound treatment 9.2421998E7 -5290000.0 -0.27 9.1648031E7 -4390000.0 -0.24 -0.3592 -0.9977 3635234 CMLD5_000076 COc1ccc(cc1)C(O)C2=CCCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D15 mock treatment 9.798571E7 269000.0 0.01 1.0070634E8 4660000.0 0.25 0.1873 0.7448 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D16 mock treatment 1.05414632E8 7700000.0 0.39 1.00831074E8 4790000.0 0.26 0.4613 0.9788 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D17 compound treatment 3.178498E7 -6.59E7 -3.38 2.9288891E7 -6.68E7 -3.59 -4.9313 -0.9995 3635235 CMLD5_000077 FC(F)(F)c1cc(NC(=S)NC(c2ccccc2)c3ccccc3)cc(c1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D18 compound treatment 9.5219171E7 -2500000.0 -0.13 9.5978398E7 -63800.0 0.0 -0.093 -0.7258 3635236 CMLD5_000078 CCOC(=O)C(C)(O)CC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D19 compound treatment 9.4755701E7 -2960000.0 -0.15 9.8701315E7 2660000.0 0.14 -0.0061 -0.0291 3635237 CMLD5_000079 CCOC(=O)C(=C)C(=O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D20 compound treatment 9.3978049E7 -3740000.0 -0.19 9.5952785E7 -89400.0 0.0 -0.1389 -0.7246 3555865 CMLD5_000080 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D21 compound treatment 2.7087736E7 -7.06E7 -3.62 2.63799E7 -6.97E7 -3.75 -5.2123 -0.9998 3635238 CMLD5_000081 CC(=O)C(=C)C(O)c1ccc2ccccc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D22 compound treatment 3.0471277E7 -6.72E7 -3.45 2.8806983E7 -6.72E7 -3.62 -4.9973 -0.9997 3635239 CMLD5_000082 COCOc1ccccc1C(=O)/C=C/c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D23 compound treatment 9.9665624E7 1950000.0 0.1 1.00483188E8 4440000.0 0.24 0.2397 0.925 3635241 CMLD5_000083 CC(=C)C(=O)/C=C/c1ccc(cc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 D24 compound treatment 1.09376782E8 1.17E7 0.6 1.11560105E8 1.55E7 0.84 1.0135 0.9865 3635243 CMLD5_000084 COC(=O)C1(CC#CC)[C@@H](CNC1=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E01 mock treatment 1.1433342E8 1.66E7 0.85 1.10654507E8 1.46E7 0.79 1.1586 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E02 mock treatment 1.06130842E8 8410000.0 0.43 1.04715642E8 8670000.0 0.47 0.6352 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E03 compound treatment 1.11282322E8 1.36E7 0.7 1.04820732E8 8780000.0 0.47 0.8259 0.9823 3635245 CMLD5_000085 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H]2O[C@@]21C)c3cc(OC)c(C)c(OC)c3OCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E04 compound treatment 1.05418105E8 7700000.0 0.39 1.03035148E8 6990000.0 0.38 0.5454 0.9997 3635246 CMLD5_000086 CO[C@@H](CCOCc1ccccc1)C[C@H]2O[C@@H](C=C[C@@H]2C)C(=O)OC(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E05 compound treatment 8.3153935E7 -1.46E7 -0.75 7.9114669E7 -1.69E7 -0.91 -1.1724 -0.9951 3635248 CMLD5_000087 COCOc1cccc2c(OCOC)c3C4=C(CCCC4)/C(=N\NS(=O)(=O)c5ccc(C)cc5)/c3c(OCOC)c12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E06 compound treatment 1.03155088E8 5440000.0 0.28 9.5915316E7 -127000.0 -0.01 0.1923 0.6896 3635250 CMLD5_000088 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@@H](NC(=O)OCC=C)c2cccc(c2)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E07 compound treatment 9.7388368E7 -329000.0 -0.02 9.3318506E7 -2720000.0 -0.15 -0.1156 -0.7831 3635252 CMLD5_000089 CC(=O)C([C@@H](NC(=O)OCC=C)c1cccs1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E08 compound treatment 1.07481369E8 9760000.0 0.5 1.02292563E8 6250000.0 0.34 0.5919 0.9814 3635254 CMLD5_000090 OP1(=O)Oc2c(c(cc3ccc4ccccc4c23)c5ccccc5)-c6c(cc7ccc8ccccc8c7c6O1)c9ccccc9 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E09 mock treatment 9.9919526E7 2200000.0 0.11 9.6063228E7 21000.0 0.0 0.0806 0.7142 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E10 mock treatment 9.6901119E7 -816000.0 -0.04 9.7010831E7 969000.0 0.05 0.0073 0.1095 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E11 compound treatment 6.2036216E7 -3.57E7 -1.83 6.4369984E7 -3.17E7 -1.71 -2.4991 -0.9994 3635255 CMLD5_000091 OC(C1CCCC1=O)c2ccc3ccccc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E12 compound treatment 1.02144693E8 4430000.0 0.23 9.9728189E7 3690000.0 0.2 0.3008 0.9978 3635256 CMLD5_000092 CC(=CCn1cnc2NCN/C(=N\OCc3ccccc3)/c21)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E13 compound treatment 9.5537604E7 -2180000.0 -0.11 9.6933694E7 891000.0 0.05 -0.045 -0.3704 3635258 CMLD5_000093 C/C=C(\C)/C(=O)C[Si](C)(C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E14 compound treatment 6.5293184E7 -3.24E7 -1.66 6.4178327E7 -3.19E7 -1.72 -2.3884 -0.9999 3635260 CMLD5_000094 CC(=O)C(=C)C(O)c1ccco1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E15 compound treatment 9.1169772E7 -6550000.0 -0.34 8.8535247E7 -7510000.0 -0.4 -0.5231 -0.9957 3635261 CMLD5_000095 COC(=O)[C@](CC=C)([C@@H](NC(=O)OC(C)(C)C)c1ccccc1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E16 compound treatment 9.5581872E7 -2140000.0 -0.11 9.6837979E7 796000.0 0.04 -0.0471 -0.4006 3635263 CMLD5_000096 CC(O)(CC=C)c1cccc(c1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E17 mock treatment 1.02612366E8 4900000.0 0.25 9.9171877E7 3130000.0 0.17 0.2966 0.9813 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E18 mock treatment 1.04159948E8 6440000.0 0.33 9.8506969E7 2460000.0 0.13 0.3274 0.9198 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E19 compound treatment 9.7770908E7 54000.0 0.0 9.7269219E7 1230000.0 0.07 0.0487 0.7361 3635264 CMLD5_000097 CC(=C)C(=O)C1CCCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E20 compound treatment 9.9581479E7 1860000.0 0.1 1.0100905E8 4970000.0 0.27 0.2567 0.9038 3635265 CMLD5_000098 COC(=O)N[C@H]([C@@H](C)[N+](=O)[O-])c1cccc(C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E21 compound treatment 8.7159879E7 -1.06E7 -0.54 8.7865421E7 -8180000.0 -0.44 -0.694 -0.9948 3635267 CMLD5_000099 C[C@]1(C[C@]2(C)[C@@H](CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E22 compound treatment 9.9512336E7 1800000.0 0.09 9.9806557E7 3760000.0 0.2 0.2084 0.9362 3635268 CMLD5_000100 COC(=O)NC(CCc1ccccc1)C(C(=O)C)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E23 compound treatment 9.2448533E7 -5270000.0 -0.27 9.4006932E7 -2040000.0 -0.11 -0.2684 -0.9211 3635269 CMLD5_000101 CC1(CC2(C)[C@H](CCc3ccco3)CC1=O)C=C2/C=C/CCc4ccco4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 E24 compound treatment 1.06975605E8 9260000.0 0.47 1.10267266E8 1.42E7 0.77 0.8772 0.9735 3635271 CMLD5_000102 COCC1=C2[C@H](CC([C@@H](C[N+](=O)[O-])c3ccccc23)(C(=O)OC)C(=O)OC)n4n(C1)c(=O)n(c5ccccc5)c4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F01 mock treatment 1.12241362E8 1.45E7 0.74 1.17699203E8 2.17E7 1.17 1.351 0.9765 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F02 mock treatment 1.19359589E8 2.16E7 1.11 1.13004368E8 1.7E7 0.91 1.4302 0.9953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F03 compound treatment 4.2894889E7 -5.48E7 -2.81 4.1026601E7 -5.5E7 -2.96 -4.0817 -0.9996 3635273 CMLD5_000103 C/C=C/C(=O)C[C@H]1CC[C@@H](C)[C@@H](CCO)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F04 compound treatment 5.7417475E7 -4.03E7 -2.07 5.5575711E7 -4.05E7 -2.18 -3.0014 -0.9996 3635275 CMLD5_000104 CC(C)OC(=O)[C@@H]1CC[C@H](C)[C@@H](CCC[C@@H]2CC=C[C@H](CC#N)O2)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F05 compound treatment 7.9777935E7 -1.79E7 -0.92 7.2734692E7 -2.33E7 -1.26 -1.5376 -0.9883 3635277 CMLD5_000105 COCOc1cccc2c(OCOC)c3C4=C(CCCC4)/C(=N\NS(=O)(=O)C)/c3c(OCOC)c12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F06 compound treatment 1.03091953E8 5380000.0 0.28 9.6040265E7 -1940.0 0.0 0.1947 0.7068 3635279 CMLD5_000106 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@@H](NC(=O)OCC=C)c2ccc(C)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F07 compound treatment 1.05877194E8 8160000.0 0.42 9.8542751E7 2500000.0 0.13 0.391 0.8898 3635281 CMLD5_000107 COC(=O)C/C=C/[C@@H](C)[C@H](NC(=O)OCC(Cl)(Cl)Cl)c1cccc(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F08 compound treatment 3.1944624E7 -6.58E7 -3.37 3.0183314E7 -6.59E7 -3.55 -4.8915 -0.9997 3635283 CMLD5_000108 CCOC(=O)C1=NO[C@]2(C1)C=C(Br)C(=O)[C@H]3O[C@H]32 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F09 mock treatment 1.05121675E8 7400000.0 0.38 9.9981401E7 3940000.0 0.21 0.4184 0.9622 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F10 mock treatment 9.7529863E7 -187000.0 -0.01 9.5518282E7 -524000.0 -0.03 -0.0267 -0.897 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F11 compound treatment 4.5097123E7 -5.26E7 -2.7 4.1672782E7 -5.44E7 -2.93 -3.9773 -0.9992 3011535 CMLD5_000109 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F12 compound treatment 4.4300845E7 -5.34E7 -2.74 4.427723E7 -5.18E7 -2.79 -3.907 -1.0 3635285 CMLD5_000110 O=C([C@@H]1O[C@H]1c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F13 compound treatment 7.5437104E7 -2.23E7 -1.14 7.6439805E7 -1.96E7 -1.06 -1.5539 -0.9992 3635286 CMLD5_000111 Cc1cc(C)cc(c1)c2cc3CCCCc3c(c2O)c4c(O)c(cc5CCCCc45)c6cc(C)cc(C)c6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F14 compound treatment 3.7568387E7 -6.01E7 -3.08 3.6547219E7 -5.95E7 -3.2 -4.4453 -0.9998 3635287 CMLD5_000112 CC(=O)C(=C)C(O)c1ccc(cc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F15 compound treatment 7.9414503E7 -1.83E7 -0.94 8.2449997E7 -1.36E7 -0.73 -1.1809 -0.9925 3635288 CMLD5_000113 COC(=O)NC(c1c[nH]c2ccc(OC)cc12)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F16 compound treatment 9.142609E7 -6290000.0 -0.32 9.1942274E7 -4100000.0 -0.22 -0.3841 -0.9829 3635289 CMLD5_000114 CC(O)(CC=C)c1cccs1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F17 mock treatment 9.4548187E7 -3170000.0 -0.16 9.5848401E7 -194000.0 -0.01 -0.1222 -0.751 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F18 mock treatment 9.9158498E7 1440000.0 0.07 9.7020316E7 978000.0 0.05 0.0895 0.9862 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F19 compound treatment 9.857023E7 853000.0 0.04 9.6205739E7 164000.0 0.01 0.0372 0.8328 3635290 CMLD5_000115 [O-][N+](=O)C[C@@H](NC(=O)OCC=C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F20 compound treatment 2.6412538E7 -7.13E7 -3.65 2.5551832E7 -7.05E7 -3.8 -5.2683 -0.9998 3635292 CMLD5_000116 CCC1CN2CCC1CC2[C@@H](NC(=S)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)c4cccc5ccc(OC)cc45 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F21 compound treatment 9.2162009E7 -5550000.0 -0.28 9.1855638E7 -4190000.0 -0.23 -0.3607 -0.9933 3635294 CMLD5_000117 COc1ccc(/C=C/C2=C[C@]3(C)C[C@]2(C)[C@@H](CC3=O)c4ccc(OC)cc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F22 compound treatment 9.7154624E7 -562000.0 -0.03 1.02394805E8 6350000.0 0.34 0.2215 0.6453 1003402 CMLD5_000118 OC(CC=C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F23 compound treatment 9.0625062E7 -7090000.0 -0.36 9.9893956E7 3850000.0 0.21 -0.1103 -0.2637 3635295 CMLD5_000119 C[C@]1(C[C@]2(C)[C@@H](CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 F24 compound treatment 1.16185166E8 1.85E7 0.95 1.15958543E8 1.99E7 1.07 1.4277 0.9981 3635296 CMLD5_000120 COC(=O)C1(CC2=CCC3C(C2Cc4ccccc4[C@@H]1C[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G01 compound treatment 1.01976848E8 4260000.0 0.22 1.02452038E8 6410000.0 0.35 0.3985 0.9756 3635298 CMLD5_000121 CCCCCCCC1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G02 compound treatment 9.694777E7 -769000.0 -0.04 9.3868707E7 -2170000.0 -0.12 -0.1106 -0.8958 3635299 CMLD5_000122 CCCCCCCC1=Cc2ccc(F)cc2C(C(C(=O)OC)C(=O)OC)N1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G03 mock treatment 1.14594744E8 1.69E7 0.87 1.09682553E8 1.36E7 0.73 1.1311 0.9967 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G04 mock treatment 1.06130492E8 8410000.0 0.43 1.06574682E8 1.05E7 0.57 0.706 0.9909 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G05 compound treatment 1.08447851E8 1.07E7 0.55 1.00841355E8 4800000.0 0.26 0.5716 0.9407 3635300 CMLD5_000123 CCOC(=O)N/N=C/c1ccccc1c2cc(OC)ccc2OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G06 compound treatment 9.9475414E7 1760000.0 0.09 9.2195195E7 -3850000.0 -0.21 -0.0828 -0.3663 3635302 CMLD5_000124 COC(=O)[C@@H]1C[C@]2([C@H]3N(Cc4ccccc4)c5ccccc52)C(=CC(=C3C(=O)OC)C(=O)OC)N1C(=O)NCc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G07 compound treatment 1.01075605E8 3360000.0 0.17 9.8003907E7 1960000.0 0.11 0.1964 0.9725 3635304 CMLD5_000125 COC(=O)C/C=C/[C@@H](C)[C@H](NC(=O)OCC(Cl)(Cl)Cl)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G08 compound treatment 9.5088675E7 -2630000.0 -0.13 9.0519683E7 -5520000.0 -0.3 -0.3055 -0.9359 3635306 CMLD5_000126 C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)NCc5ccco5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G09 compound treatment 9.9069723E7 1350000.0 0.07 9.4103798E7 -1940000.0 -0.1 -0.0248 -0.1978 3635308 CMLD5_000127 CC1(C)CCC(=CC1)O[Si](C)(c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G10 compound treatment 9.6186956E7 -1530000.0 -0.08 9.1284867E7 -4760000.0 -0.26 -0.2366 -0.8831 3131447 CMLD5_000128 O=C(OCc1ccccc1)C(C2CCCC(=O)C2)C(=O)OCc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G11 compound treatment 9.7859277E7 142000.0 0.01 9.4455404E7 -1590000.0 -0.09 -0.0553 -0.6444 3635309 CMLD5_000129 CC1COc2ccccc2C1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G12 compound treatment 8.0997104E7 -1.67E7 -0.86 8.3331667E7 -1.27E7 -0.68 -1.0899 -0.9938 3635310 CMLD5_000130 CC1(C)C[C@@](C)(C=C1c2ccccc2)C(=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G13 compound treatment 2.8178749E7 -6.95E7 -3.56 2.8607462E7 -6.74E7 -3.63 -5.0879 -1.0 3635312 CMLD5_000131 Oc1ccc2CCCCc2c1c3c(O)c(Br)cc4CCCCc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G14 compound treatment 5.5368175E7 -4.23E7 -2.17 5.719912E7 -3.88E7 -2.09 -3.0138 -0.9998 3635313 CMLD5_000132 CC(=O)C(=C)C(O)c1cccs1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G15 compound treatment 9.3289217E7 -4430000.0 -0.23 9.3069731E7 -2970000.0 -0.16 -0.2737 -0.9854 3635314 CMLD5_000133 COC(=O)C([C@@H](NC(=O)OC(C)(C)C)c1ccccc1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G16 compound treatment 9.5962354E7 -1750000.0 -0.09 9.2813235E7 -3230000.0 -0.17 -0.1865 -0.9529 3635316 CMLD5_000134 CCC/C=C/C(C)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G17 compound treatment 9.3317034E7 -4400000.0 -0.23 9.5875233E7 -167000.0 -0.01 -0.1658 -0.7347 1026004 CMLD5_000135 COc1ccc2ccccc2c1c3c(OC)ccc4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G18 compound treatment 9.1368668E7 -6350000.0 -0.33 9.2773749E7 -3270000.0 -0.18 -0.3545 -0.9584 3635318 CMLD5_000136 COC(=O)N[C@@H](CCc1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G19 mock treatment 9.311639E7 -4600000.0 -0.24 9.8103376E7 2060000.0 0.11 -0.0882 -0.3386 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G20 mock treatment 1.00174365E8 2460000.0 0.13 9.6907983E7 866000.0 0.05 0.122 0.9086 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G21 compound treatment 9.2097646E7 -5620000.0 -0.29 9.518273E7 -859000.0 -0.05 -0.2364 -0.8103 3635320 CMLD5_000137 CC[C@]1(C[C@]2(CC)[C@@H](CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G22 compound treatment 9.4218944E7 -3500000.0 -0.18 9.9018838E7 2980000.0 0.16 -0.0134 -0.0558 3635321 CMLD5_000138 C[C@](O)(CC=C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G23 compound treatment 8.964177E7 -8080000.0 -0.41 1.01425337E8 5380000.0 0.29 -0.0877 -0.1735 3635322 CMLD5_000139 CC(=C)C(O)/C=C/c1ccc(cc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 G24 compound treatment 9.9519856E7 1800000.0 0.09 1.11773042E8 1.57E7 0.85 0.6643 0.7796 3635324 CMLD5_000140 COC(=O)C1(C[C@H]2CON=C2[C@H]1c3ccccc3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H01 compound treatment 1.13742343E8 1.6E7 0.82 1.14700123E8 1.87E7 1.0 1.2912 0.995 3635326 CMLD5_000141 CCCCCCCc1cc2=C(Cl)C(=O)C(C)(OC(=O)C)C(=c2cn1)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H02 compound treatment 1.0275074E8 5030000.0 0.26 9.8446377E7 2400000.0 0.13 0.274 0.9491 3635327 CMLD5_000142 COC(=O)N1C(CC(=O)C)c2ccccc2C=C1C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H03 mock treatment 1.14273024E8 1.66E7 0.85 1.07157747E8 1.11E7 0.6 1.0233 0.9854 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H04 mock treatment 1.10058148E8 1.23E7 0.63 9.66279E7 586000.0 0.03 0.4696 0.7414 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H05 compound treatment 2.9987852E7 -6.77E7 -3.47 3.1927837E7 -6.41E7 -3.45 -4.8959 -1.0 3635328 CMLD5_000143 CO[C@H](Cc1ccccc1Br)[C@H](C)/C=C/CC(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H06 compound treatment 1.0415228E8 6440000.0 0.33 9.8779671E7 2740000.0 0.15 0.3375 0.9341 3635330 CMLD5_000144 CC(=O)C([C@@H](NC(=O)OCC=C)c1ccc(Br)cc1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H07 compound treatment 1.03508647E8 5790000.0 0.3 9.9328907E7 3290000.0 0.18 0.3351 0.9695 3635332 CMLD5_000145 CC(=O)C([C@H](CCc1ccccc1)NC(=O)OCC=C)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H08 compound treatment 9.8454032E7 737000.0 0.04 9.2502984E7 -3540000.0 -0.19 -0.1081 -0.5561 3635334 CMLD5_000146 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCc4ccc5OCOc5c4)c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H09 compound treatment 9.8872233E7 1160000.0 0.06 9.4384391E7 -1660000.0 -0.09 -0.0213 -0.1984 3635335 CMLD5_000147 CC(C1CCCC(=O)C1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H10 compound treatment 1.03061657E8 5340000.0 0.27 9.6360332E7 318000.0 0.02 0.2058 0.7499 3011274 CMLD5_000148 CC(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H11 compound treatment 6.7316473E7 -3.04E7 -1.56 6.2622873E7 -3.34E7 -1.8 -2.3743 -0.9974 3635336 CMLD5_000149 Oc1c(CN2CCOCC2)cc3CCCCc3c1c4c(O)c(CN5CCOCC5)cc6CCCCc46 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H12 compound treatment 5.8929768E7 -3.88E7 -1.99 5.5903015E7 -4.01E7 -2.16 -2.9341 -0.9991 3635337 CMLD5_000150 OC(C1=CCCC1=O)c2ccc(Cl)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H13 compound treatment 8.4415884E7 -1.33E7 -0.68 8.0678918E7 -1.54E7 -0.83 -1.0671 -0.9954 3635208 CMLD5_000151 OC(C1=CCCC1=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H14 compound treatment 3.388203E7 -6.38E7 -3.27 3.3313719E7 -6.27E7 -3.38 -4.702 -0.9999 3635338 CMLD5_000152 CC(=O)C(=C)C(O)c1ccc(Cl)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H15 compound treatment 8.3508778E7 -1.42E7 -0.73 8.1058702E7 -1.5E7 -0.81 -1.0855 -0.9987 3635339 CMLD5_000153 C[C@@]1(CCC=C2[C@@H]1CCCC2=O)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H16 compound treatment 9.0997551E7 -6720000.0 -0.34 8.9033406E7 -7010000.0 -0.38 -0.5104 -0.999 3635341 CMLD5_000154 CC(O)(CC=C)c1ccco1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H17 compound treatment 9.8939502E7 1220000.0 0.06 9.9679852E7 3640000.0 0.2 0.1828 0.8889 3635342 CMLD5_000155 CC(C)(C)OC(=O)N1CCC[C@H]1C(O)(c2ccccc2)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H18 compound treatment 8.698969E7 -1.07E7 -0.55 9.1236279E7 -4810000.0 -0.26 -0.5718 -0.9409 3635344 CMLD5_000156 COCC(=O)C(C(NC(=O)OCC=C)c1ccc(F)c(F)c1)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H19 mock treatment 9.4764804E7 -2950000.0 -0.15 9.8310878E7 2270000.0 0.12 -0.0206 -0.1059 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H20 mock treatment 9.3962254E7 -3750000.0 -0.19 9.5893955E7 -148000.0 -0.01 -0.1417 -0.7358 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H21 compound treatment 9.3608258E7 -4110000.0 -0.21 9.8132334E7 2090000.0 0.11 -0.0693 -0.2903 3635322 CMLD5_000157 CC(=C)C(O)/C=C/c1ccc(cc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H22 compound treatment 9.8332056E7 615000.0 0.03 1.02732875E8 6690000.0 0.36 0.2771 0.7661 3635345 CMLD5_000158 COC(=O)NC(C(C(=O)OC)C(=O)OC)c1ccc2OCOc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H23 compound treatment 1.00424512E8 2710000.0 0.14 1.08339933E8 1.23E7 0.66 0.5664 0.8371 3635346 CMLD5_000159 Fc1cc(F)c(F)c(/C=C/NC=O)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 H24 compound treatment 1.04107539E8 6390000.0 0.33 1.1097696E8 1.49E7 0.8 0.8003 0.9216 3635348 CMLD5_000160 COC(=O)C1(C[C@@H]2CON=C2[C@H]1c3ccccc3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I01 compound treatment 1.09526374E8 1.18E7 0.61 1.1156878E8 1.55E7 0.84 1.0192 0.9874 3635349 CMLD5_000161 CCCCCCCC1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CN1C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I02 compound treatment 1.12341636E8 1.46E7 0.75 1.06541758E8 1.05E7 0.57 0.9298 0.9903 3635350 CMLD5_000162 COC(=O)C(C1N(C(=O)OC)C(=Cc2ccccc12)C3CC3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I03 compound treatment 1.10401721E8 1.27E7 0.65 1.04379835E8 8340000.0 0.45 0.7772 0.9837 3635351 CMLD5_000163 COC[C@@H](O)[C@@H](OC)[C@H](OC)[C@H](Cc1c(OC)cc(OC)cc1OC)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I04 compound treatment 1.08352827E8 1.06E7 0.55 1.00439417E8 4400000.0 0.24 0.5529 0.9303 3635353 CMLD5_000164 CC(C)OC(=O)[C@@H]1CC[C@H](C)[C@@H](CCC[C@@H]2C[C@H](C[C@H](CC#N)O2)OC(=O)[C@@H](OC(=O)C)c3ccccc3)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I05 mock treatment 1.03465572E8 5750000.0 0.29 9.9247659E7 3210000.0 0.17 0.3304 0.9676 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I06 mock treatment 1.04008709E8 6290000.0 0.32 9.7779433E7 1740000.0 0.09 0.2942 0.8761 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I07 compound treatment 1.05922231E8 8210000.0 0.42 9.8590165E7 2550000.0 0.14 0.3944 0.8916 3635243 CMLD5_000165 COC(=O)C1(CC#CC)[C@@H](CNC1=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I08 compound treatment 9.6396434E7 -1320000.0 -0.07 8.9178239E7 -6860000.0 -0.37 -0.3092 -0.8229 3635355 CMLD5_000166 COC(=O)/C(=N/O)/Cc1cc(Br)c(OC)c(Br)c1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I09 compound treatment 7.7899842E7 -1.98E7 -1.02 7.4382696E7 -2.17E7 -1.17 -1.5429 -0.9976 3635357 CMLD5_000167 CC(=C)C(=O)c1ccc2OCOc2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I10 compound treatment 9.5673723E7 -2040000.0 -0.1 9.221968E7 -3820000.0 -0.21 -0.2196 -0.9509 3010142 CMLD5_000168 CC(C)[C@H](O)C1=CCCCC1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I11 compound treatment 9.4673829E7 -3040000.0 -0.16 9.2858286E7 -3180000.0 -0.17 -0.2315 -0.9989 3635358 CMLD5_000169 CC(=O)CCOC1CCCCO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I12 compound treatment 3.611345E7 -6.16E7 -3.16 3.6987793E7 -5.91E7 -3.18 -4.4813 -1.0 3635359 CMLD5_000170 CCOC(=O)/C=C/CCC\C=C\C(=O)C(=C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I13 compound treatment 5.7405307E7 -4.03E7 -2.07 5.5233045E7 -4.08E7 -2.2 -3.0149 -0.9995 3635361 CMLD5_000171 CC(=O)C(=C)C(O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I14 compound treatment 8.8118405E7 -9600000.0 -0.49 8.6326029E7 -9720000.0 -0.52 -0.7178 -0.9995 3635362 CMLD5_000172 Fc1ccc(cc1F)C(NC(=O)OCC=C)S(=O)(=O)c2ccc(Cl)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I15 compound treatment 9.0775943E7 -6940000.0 -0.36 9.0433619E7 -5610000.0 -0.3 -0.4651 -0.9967 3635363 CMLD5_000173 CC(CCC#N)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I16 compound treatment 8.612187E7 -1.16E7 -0.59 8.6398548E7 -9640000.0 -0.52 -0.7874 -0.9977 3635141 CMLD5_000174 CC(O)C#C[Si](C)(C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I17 compound treatment 8.6306756E7 -1.14E7 -0.58 9.0865236E7 -5180000.0 -0.28 -0.6106 -0.9426 3635364 CMLD5_000175 COC(=O)C(=C)Nc1ccc(OC)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I18 compound treatment 9.1166837E7 -6550000.0 -0.34 9.4419636E7 -1620000.0 -0.09 -0.2992 -0.8624 3635365 CMLD5_000176 C[C@@H](C=C)[C@](C)(O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I19 compound treatment 9.3258277E7 -4460000.0 -0.23 9.7341524E7 1300000.0 0.07 -0.1121 -0.4691 3635366 CMLD5_000177 Cc1nc2ccccc2oc1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I20 compound treatment 9.1545595E7 -6170000.0 -0.32 9.8191815E7 2150000.0 0.12 -0.1418 -0.421 3635367 CMLD5_000178 COC(=O)NC(c1ccccc1)C2(C(=O)OCC=C)C(=O)Cc3ccccc32 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I21 mock treatment 9.493136E7 -2790000.0 -0.14 9.6883394E7 841000.0 0.05 -0.0689 -0.4601 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I22 mock treatment 9.3177428E7 -4540000.0 -0.23 9.9034211E7 2990000.0 0.16 -0.0506 -0.1787 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I23 compound treatment 9.8788389E7 1070000.0 0.05 1.02591881E8 6550000.0 0.35 0.2882 0.8075 3635368 CMLD5_000179 COC(=O)C([C@@H](NC=O)c1ccccc1)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 I24 compound treatment 8.6249284E7 -1.15E7 -0.59 8.659748E7 -9440000.0 -0.51 -0.7752 -0.9974 3635370 CMLD5_000180 COC(=O)C1(CC(CO)C(=O)[C@H]1c2ccccc2)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J01 compound treatment 1.15608216E8 1.79E7 0.92 1.1466354E8 1.86E7 1.0 1.3575 0.999 3635372 CMLD5_000181 CCCCCCCC1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CN1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J02 compound treatment 1.05410347E8 7690000.0 0.39 9.8964788E7 2920000.0 0.16 0.3901 0.9189 3635373 CMLD5_000182 CCCCCCCC1=Cc2ccc(F)cc2C(C(C(=O)C)C(=O)OC)N1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J03 compound treatment 1.08187558E8 1.05E7 0.54 1.04261058E8 8220000.0 0.44 0.6924 0.9954 3635190 CMLD5_000183 COC(=O)[C@H]1O[C@H]([C@H](C)[C@H]2O[C@]21C)c3cc(OC)c(C)c(OC)c3OCc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J04 compound treatment 7.9307266E7 -1.84E7 -0.94 7.8599912E7 -1.74E7 -0.94 -1.3314 -1.0 3635374 CMLD5_000184 CC(C)OC(=O)[C@H]1O[C@H](CCCCOCc2ccccc2)[C@@H](C)[C@H]3O[C@H]31 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J05 mock treatment 1.05356752E8 7640000.0 0.39 1.01478197E8 5440000.0 0.29 0.4839 0.9897 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J06 mock treatment 1.06484144E8 8770000.0 0.45 9.957144E7 3530000.0 0.19 0.4521 0.9267 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J07 compound treatment 9.6531052E7 -1190000.0 -0.06 8.8664026E7 -7380000.0 -0.4 -0.3239 -0.8059 3635376 CMLD5_000185 COC(=O)C1(CC2=CC[C@H]3[C@@H]([C@@H]2Cc4ccccc4[C@@H]1C[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J08 compound treatment 2.6710047E7 -7.1E7 -3.64 2.5929277E7 -7.01E7 -3.78 -5.2431 -0.9998 3555609 CMLD5_000186 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J09 compound treatment 9.2437029E7 -5280000.0 -0.27 8.736933E7 -8670000.0 -0.47 -0.5216 -0.9663 3635377 CMLD5_000187 C/C(=C\CO)/CCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J10 compound treatment 8.9798906E7 -7920000.0 -0.41 8.359958E7 -1.24E7 -0.67 -0.7608 -0.9711 3131710 CMLD5_000188 CCOC(=O)CC(C1CCCCC1=O)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J11 compound treatment 6.0609366E7 -3.71E7 -1.9 5.8212954E7 -3.78E7 -2.04 -2.7853 -0.9994 3635234 CMLD5_000189 COc1ccc(cc1)C(O)C2=CCCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J12 compound treatment 9.1968645E7 -5750000.0 -0.29 8.4077591E7 -1.2E7 -0.64 -0.6639 -0.9371 3635379 CMLD5_000190 COc1ccc2CCCCc2c1c3c(OC)c(Br)cc4CCCCc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J13 compound treatment 8.3193087E7 -1.45E7 -0.74 7.7809151E7 -1.82E7 -0.98 -1.2206 -0.9907 3635344 CMLD5_000191 COCC(=O)C(C(NC(=O)OCC=C)c1ccc(F)c(F)c1)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J14 compound treatment 2.8642059E7 -6.91E7 -3.54 2.96372E7 -6.64E7 -3.58 -5.0319 -1.0 3635380 CMLD5_000192 COc1cccc(c1)C(O)C(=C)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J15 compound treatment 6.0234892E7 -3.75E7 -1.92 5.8919798E7 -3.71E7 -2.0 -2.7719 -0.9998 3635381 CMLD5_000193 Cc1ccc(cc1)C(O)C2=CCCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J16 compound treatment 7.7498539E7 -2.02E7 -1.04 8.2079914E7 -1.4E7 -0.75 -1.2644 -0.9876 2069487 CMLD5_000194 COc1ccc(/N=C/c2ccccc2)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J17 compound treatment 8.285478E7 -1.49E7 -0.76 9.2863247E7 -3180000.0 -0.17 -0.6597 -0.8449 3635382 CMLD5_000195 O[C@H]([C@@H](O)C(=O)OCC(F)(F)F)C(=O)OCC(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J18 compound treatment 8.4182021E7 -1.35E7 -0.69 8.7789767E7 -8250000.0 -0.44 -0.8048 -0.9768 3635384 CMLD5_000196 CCOC(=O)C(CC=C)(Nc1ccc(OC)cc1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J19 compound treatment 8.3245629E7 -1.45E7 -0.74 8.6945904E7 -9100000.0 -0.49 -0.8708 -0.9797 3635385 CMLD5_000197 COC(=O)N[C@H](C[N+](=O)[O-])/C=C/c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J20 compound treatment 9.4197555E7 -3520000.0 -0.18 9.6730232E7 688000.0 0.04 -0.1013 -0.5504 3635387 CMLD5_000198 O=C1NC[C@@H](N1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J21 mock treatment 9.174134E7 -5980000.0 -0.31 9.664669E7 604000.0 0.03 -0.1935 -0.6284 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J22 mock treatment 9.2701252E7 -5020000.0 -0.26 9.7466138E7 1420000.0 0.08 -0.1276 -0.4755 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J23 compound treatment 1.08937291E8 1.12E7 0.58 1.07158644E8 1.11E7 0.6 0.8299 0.9998 3635388 CMLD5_000199 COC(=O)C([C@@H](NC(=O)OCc1ccccc1)c2ccccc2)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 J24 compound treatment 1.0226524E8 4550000.0 0.23 1.12291776E8 1.62E7 0.88 0.7836 0.8653 3635390 CMLD5_000200 COCC1=C2C(CC([C@@H](C[N+](=O)[O-])c3ccccc23)(C(=O)OC)C(=O)OC)C4C(C1)C(=O)N(C4=O)c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K01 compound treatment 1.02111778E8 4390000.0 0.23 9.6872131E7 830000.0 0.04 0.1909 0.8312 3635392 CMLD5_000201 COC(=O)C([C@@H]1O[C@]23COC=C[C@]3(C)[C@H]2c4ccccc14)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K02 compound treatment 1.06214916E8 8500000.0 0.44 1.06109202E8 1.01E7 0.54 0.6913 0.9941 3635394 CMLD5_000202 COC(=O)C(C1N(C(=O)OC)C(=Cc2ccccc12)/C=C/C)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K03 compound treatment 1.07355656E8 9640000.0 0.49 1.06531988E8 1.05E7 0.56 0.7488 0.9978 3635396 CMLD5_000203 OC[C@@H](O)[C@@H](O)CCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K04 compound treatment 1.08244995E8 1.05E7 0.54 9.6291644E7 249000.0 0.01 0.391 0.7245 3635398 CMLD5_000204 CO[C@@H](CCO)C[C@H]1O[C@@H](CC[C@@H]1C)C(=O)OC(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K05 compound treatment 8.2223396E7 -1.55E7 -0.79 7.5491607E7 -2.06E7 -1.11 -1.344 -0.9867 3635400 CMLD5_000205 CO[C@H]1[C@H](C)/C(=C/CCOC(=O)C\C=C\c2ccccc2)/c3ccc(F)cc13 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K06 compound treatment 9.5213376E7 -2500000.0 -0.13 8.5019287E7 -1.1E7 -0.59 -0.5105 -0.8405 3635402 CMLD5_000206 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@H](Cc2ccccc2)NC(=O)OCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K07 mock treatment 1.00552085E8 2840000.0 0.15 9.4161673E7 -1880000.0 -0.1 0.0311 0.1758 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K08 mock treatment 9.9419697E7 1700000.0 0.09 8.5012261E7 -1.1E7 -0.59 -0.3583 -0.5968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K09 compound treatment 9.4290069E7 -3430000.0 -0.18 8.6579858E7 -9460000.0 -0.51 -0.4845 -0.8989 3635404 CMLD5_000207 O=C(Oc1ccccc1)[C@H]2O[C@@H]2c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K10 compound treatment 2.8544766E7 -6.92E7 -3.55 2.9542287E7 -6.65E7 -3.58 -5.0391 -1.0 3635405 CMLD5_000208 CC(=C)C(=O)/C=C/C=C/c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K11 compound treatment 9.7960251E7 243000.0 0.01 9.092664E7 -5120000.0 -0.28 -0.186 -0.6744 1069385 CMLD5_000209 Cc1ccc(cc1)S(=O)(=O)OCCc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K12 compound treatment 2.7483588E7 -7.02E7 -3.6 2.6903282E7 -6.91E7 -3.72 -5.178 -0.9999 3635407 CMLD5_000210 Brc1ccc2n(CC3CO3)c4ccc(Br)cc4c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K13 compound treatment 8.8907625E7 -8810000.0 -0.45 8.076472E7 -1.53E7 -0.82 -0.901 -0.9601 3635408 CMLD5_000211 COC(=O)C(C(NC(=O)OCC=C)c1ccc(F)c(F)c1)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K14 compound treatment 2.6490523E7 -7.12E7 -3.65 2.5831849E7 -7.02E7 -3.78 -5.2548 -0.9998 3635409 CMLD5_000212 CC(=O)C(=C)C(O)c1cccc(Br)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K15 mock treatment 8.2579019E7 -1.51E7 -0.78 8.2723602E7 -1.33E7 -0.72 -1.0558 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K16 mock treatment 8.037671E7 -1.73E7 -0.89 8.2109056E7 -1.39E7 -0.75 -1.159 -0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K17 compound treatment 8.6204371E7 -1.15E7 -0.59 9.066436E7 -5380000.0 -0.29 -0.622 -0.9463 3635410 CMLD5_000213 O[C@H]([C@@H](O)C(=O)OCC=C)C(=O)OCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K18 compound treatment 8.5130263E7 -1.26E7 -0.65 8.8961784E7 -7080000.0 -0.38 -0.7258 -0.9685 3635412 CMLD5_000214 COC(=O)C(C(Cc1cc(F)cc(F)c1F)NC=O)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K19 compound treatment 8.5954655E7 -1.18E7 -0.6 9.2913925E7 -3130000.0 -0.17 -0.5454 -0.8713 3635413 CMLD5_000215 COC(=O)NC(C(=O)OC)(C(=O)OC)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K20 compound treatment 8.9309283E7 -8410000.0 -0.43 9.4989959E7 -1050000.0 -0.06 -0.3448 -0.7933 3635414 CMLD5_000216 COC(=O)/C(=N\c1ccc(OC)cc1)/CC(NC(=O)OCC=C)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K21 compound treatment 9.5828627E7 -1890000.0 -0.1 9.5912582E7 -130000.0 -0.01 -0.0734 -0.7561 3635416 CMLD5_000217 COc1ccc(NC2=CC(N(C2=O)c3ccc(OC)cc3)c4ccccc4)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K22 compound treatment 8.6380807E7 -1.13E7 -0.58 9.4179539E7 -1860000.0 -0.1 -0.4818 -0.8171 3635417 CMLD5_000218 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K23 mock treatment 9.1763978E7 -5950000.0 -0.31 9.9989615E7 3950000.0 0.21 -0.0654 -0.176 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 K24 mock treatment 1.00246887E8 2530000.0 0.13 1.09602045E8 1.36E7 0.73 0.608 0.8198 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L01 compound treatment 1.05771997E8 8060000.0 0.41 1.18221055E8 2.22E7 1.19 1.1365 0.8993 3635419 CMLD5_000219 COC(=O)N1[C@H]2CC[C@@]3(C)CC(=O)C[C@]1(C)C3c4ccccc24 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L02 compound treatment 9.4118012E7 -3600000.0 -0.18 8.527566E7 -1.08E7 -0.58 -0.5404 -0.8882 3635421 CMLD5_000220 COC(=O)C(C1N(C(=O)OC)C(=Cc2ccccc12)C)c3ccc(OC)c(OC)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L03 compound treatment 1.07035262E8 9320000.0 0.48 1.05625515E8 9580000.0 0.52 0.7026 0.9993 3635422 CMLD5_000221 COc1cc(OC)c([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(OC)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L04 compound treatment 1.03049735E8 5330000.0 0.27 9.8980721E7 2940000.0 0.16 0.3052 0.9662 3635424 CMLD5_000222 CCCCCCCc1cc2ccccc2c(=O)o1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L05 compound treatment 1.07223785E8 9510000.0 0.49 1.01141438E8 5100000.0 0.27 0.5387 0.9632 3635425 CMLD5_000223 CO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1c2OCOc2ccc1Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L06 compound treatment 9.6286146E7 -1430000.0 -0.07 9.1383887E7 -4660000.0 -0.25 -0.2292 -0.8771 3635427 CMLD5_000224 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@@H](NC(=O)OCC=C)c2ccc(Br)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L07 mock treatment 9.9170351E7 1450000.0 0.07 9.5769896E7 -272000.0 -0.01 0.0423 0.5572 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L08 mock treatment 9.3559503E7 -4160000.0 -0.21 8.728287E7 -8760000.0 -0.47 -0.4842 -0.9355 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L09 compound treatment 8.1661312E7 -1.61E7 -0.82 7.4708585E7 -2.13E7 -1.15 -1.3942 -0.9866 3635429 CMLD5_000225 COc1ccc(cc1)C(=O)[C@@]2(C)C[C@@H](C)C(=C2)c3ccc(OC)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L10 compound treatment 9.2302911E7 -5410000.0 -0.28 8.590203E7 -1.01E7 -0.55 -0.5823 -0.9507 3635431 CMLD5_000226 CC1(C)OCC(CO1)[C@H](O)C2=CCCCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L11 compound treatment 9.1146716E7 -6570000.0 -0.34 7.836412E7 -1.77E7 -0.95 -0.9113 -0.9024 3635432 CMLD5_000227 CCOC(=O)/C=C/CCCC=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L12 compound treatment 2.6738272E7 -7.1E7 -3.64 2.6041184E7 -7.0E7 -3.77 -5.2379 -0.9998 3635434 CMLD5_000228 CCOC(=O)/C=C/CCC\C=C\C(=O)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L13 compound treatment 4.4320388E7 -5.34E7 -2.74 4.1841233E7 -5.42E7 -2.92 -3.999 -0.9995 3635436 CMLD5_000229 CC(C)(O)C(=O)C(=C)C(O)c1ccc(cc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L14 compound treatment 7.375746E7 -2.4E7 -1.23 7.1784012E7 -2.43E7 -1.31 -1.792 -0.9995 3635437 CMLD5_000230 CC(=O)C(=C)C(O)/C=C/c1ccco1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L15 mock treatment 7.8449963E7 -1.93E7 -0.99 8.0496153E7 -1.55E7 -0.84 -1.2902 -0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L16 mock treatment 7.6503418E7 -2.12E7 -1.09 8.4498064E7 -1.15E7 -0.62 -1.2084 -0.9648 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L17 compound treatment 8.3457162E7 -1.43E7 -0.73 8.5131992E7 -1.09E7 -0.59 -0.9322 -0.9941 3635439 CMLD5_000231 CCOC(=O)C([C@H](CCc1ccccc1)NC(=O)OC)C(=O)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L18 compound treatment 8.5315668E7 -1.24E7 -0.64 8.7319655E7 -8720000.0 -0.47 -0.7816 -0.9889 3635441 CMLD5_000232 CC(O)(CC=C)/C=C/c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L19 compound treatment 8.7357538E7 -1.04E7 -0.53 8.7869482E7 -8170000.0 -0.44 -0.6866 -0.9957 3635443 CMLD5_000233 COC(=O)C(C(=O)OC)c1ccccc1[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L20 compound treatment 9.023242E7 -7480000.0 -0.38 9.0297461E7 -5740000.0 -0.31 -0.49 -0.9943 3635444 CMLD5_000234 COC(=O)NC(/C=C/c1ccccc1)C(C(=O)C)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L21 compound treatment 9.2572285E7 -5140000.0 -0.26 9.1419266E7 -4620000.0 -0.25 -0.3625 -0.9996 3635446 CMLD5_000235 CC(O)(CC=C)C#Cc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L22 compound treatment 9.0874992E7 -6840000.0 -0.35 9.3868081E7 -2170000.0 -0.12 -0.3307 -0.8946 3635447 CMLD5_000236 COC(=O)NC(c1c[nH]c2ccccc12)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L23 mock treatment 9.7075838E7 -641000.0 -0.03 1.01905084E8 5860000.0 0.32 0.2 0.6301 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 L24 mock treatment 1.04256773E8 6540000.0 0.34 1.10713649E8 1.47E7 0.79 0.7957 0.9271 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M01 compound treatment 1.24231256E8 2.65E7 1.36 1.18916701E8 2.29E7 1.23 1.8319 0.9988 3635448 CMLD5_000237 COC(=O)CC1N(C(=O)OC)C(=Cc2ccccc12)C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M02 compound treatment 1.04860296E8 7140000.0 0.37 9.6657148E7 615000.0 0.03 0.2823 0.7679 3635449 CMLD5_000238 COC(=O)N1C(C/C(=C/C(=O)C)/C)c2ccccc2C=C1C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M03 compound treatment 1.07095496E8 9380000.0 0.48 9.9770468E7 3730000.0 0.2 0.4819 0.925 3635451 CMLD5_000239 COC(=O)[C@H]1O[C@@H](CCOc2ccccc2)[C@@H](C)C=C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M04 compound treatment 1.08174235E8 1.05E7 0.54 1.02717832E8 6680000.0 0.36 0.6332 0.9811 3635453 CMLD5_000240 C/C=C/C1=CC2=CC(=O)C(C)(OC(=O)c3c(C)cc(O)cc3O)C(=O)C2=CO1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M05 compound treatment 9.757677E7 -140000.0 -0.01 8.7336535E7 -8710000.0 -0.47 -0.3366 -0.7179 3635455 CMLD5_000241 COC(=O)C/C=C/[C@@H](C)[C@H](O)c1ccccc1Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M06 compound treatment 9.1076122E7 -6640000.0 -0.34 8.2011304E7 -1.4E7 -0.76 -0.7749 -0.9351 3635457 CMLD5_000242 COC(=O)[C@H](Cc1c[nH]c2ccccc12)Nc3nnc(C(=O)OC)c(n3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M07 compound treatment 9.6080184E7 -1640000.0 -0.08 8.8092754E7 -7950000.0 -0.43 -0.362 -0.8299 3635459 CMLD5_000243 COC(=O)C1(CC=CCc2ccccc2[C@@H]1C[N+](=O)[O-])C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M08 compound treatment 9.9484583E7 1770000.0 0.09 9.3626121E7 -2420000.0 -0.13 -0.0279 -0.1762 3635461 CMLD5_000244 C[C@H]1/C=C/CC(=O)NCc2cccc(CNC(=O)N[C@H]1c3ccccc3)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M09 mock treatment 9.4178333E7 -3540000.0 -0.18 8.2780865E7 -1.33E7 -0.71 -0.6332 -0.8594 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M10 mock treatment 9.3232036E7 -4480000.0 -0.23 8.3910551E7 -1.21E7 -0.65 -0.6245 -0.9017 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M11 compound treatment 8.9379048E7 -8340000.0 -0.43 7.6727328E7 -1.93E7 -1.04 -1.0377 -0.9228 1039317 CMLD5_000245 O=C1CCCC(=C1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M12 compound treatment 6.4168691E7 -3.35E7 -1.72 5.8823568E7 -3.72E7 -2.0 -2.633 -0.9971 3635463 CMLD5_000246 OC(C[N+](=O)[O-])c1ccc(cc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M13 mock treatment 8.6746678E7 -1.1E7 -0.56 7.7844251E7 -1.82E7 -0.98 -1.0905 -0.9652 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M14 mock treatment 8.32512E7 -1.45E7 -0.74 7.6782472E7 -1.93E7 -1.04 -1.2576 -0.9865 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M15 compound treatment 3.7396348E7 -6.03E7 -3.09 3.9779764E7 -5.63E7 -3.03 -4.3285 -0.9999 3635464 CMLD5_000247 C=C[C@H]1CCC=C2[C@@H]1CCCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M16 compound treatment 7.1717472E7 -2.6E7 -1.33 7.3165341E7 -2.29E7 -1.23 -1.8134 -0.9992 3635466 CMLD5_000248 CC(O)(CC=C)c1cccc(Br)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M17 compound treatment 7.8445495E7 -1.93E7 -0.99 8.048537E7 -1.56E7 -0.84 -1.2908 -0.9966 3635467 CMLD5_000249 CCOC(=O)/C(=N/NC(=O)C)/C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M18 compound treatment 8.370825E7 -1.4E7 -0.72 8.5507085E7 -1.05E7 -0.57 -0.9088 -0.9932 3635469 CMLD5_000250 OC1(CC=C)CCOc2ccccc21 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M19 compound treatment 8.7474489E7 -1.02E7 -0.52 8.0771558E7 -1.53E7 -0.82 -0.9527 -0.9765 3555939 CMLD5_000251 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M20 compound treatment 8.5325739E7 -1.24E7 -0.64 8.5227503E7 -1.08E7 -0.58 -0.8609 -0.9991 3635470 CMLD5_000252 COC(=O)N[C@H](C(C(=O)OC)C(=O)OC)c1ccc(Br)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M21 compound treatment 1.01104784E8 3390000.0 0.17 1.00234226E8 4190000.0 0.23 0.2824 0.9916 3635472 CMLD5_000253 COC(=O)N[C@H]([C@@H](C)[N+](=O)[O-])c1cccc(F)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M22 compound treatment 9.3096703E7 -4620000.0 -0.24 9.3420562E7 -2620000.0 -0.14 -0.2673 -0.9695 3635474 CMLD5_000254 COC(=O)NC1C=CCCC1C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M23 compound treatment 9.7004921E7 -712000.0 -0.04 9.742884E7 1390000.0 0.07 0.027 0.3248 3635475 CMLD5_000255 CCOC(=O)C(C)(CC=C)Nc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 M24 compound treatment 8.5155207E7 -1.26E7 -0.64 9.2144685E7 -3900000.0 -0.21 -0.6037 -0.8914 3635476 CMLD5_000256 COC(=O)C1(CC2=C[C@H](CC2=O)Cc3ccccc3[C@@H]1C[N+](=O)[O-])C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N01 compound treatment 1.1129295E8 1.36E7 0.7 9.8738242E7 2700000.0 0.15 0.5947 0.8366 3635477 CMLD5_000257 CCCCCCCC1Cc2ccccc2C(C(C(=O)OC)C(=O)OC)N1C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N02 compound treatment 1.14167023E8 1.65E7 0.84 1.0978121E8 1.37E7 0.74 1.1193 0.9979 3635478 CMLD5_000258 CC(C)OC(=O)[C@@H]1CC[C@H](C)[C@@H](CCCCO)O1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N03 compound treatment 9.2990277E7 -4730000.0 -0.24 7.9141877E7 -1.69E7 -0.91 -0.8148 -0.8652 3635480 CMLD5_000259 COC(=O)C1=C(C)[C@@H](O)[C@@H](C)[C@@](C)(O1)c2cc(OC)c(C)c(OC)c2COc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N04 compound treatment 7.8995118E7 -1.87E7 -0.96 7.8156605E7 -1.79E7 -0.96 -1.3596 -1.0 3635482 CMLD5_000260 Cc1cc(O)cc(O)c1C(=O)OC2(C)C(=O)C=C3C=C(OC=C3C2=O)/C=C/C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N05 compound treatment 3.2027101E7 -6.57E7 -3.37 2.9949658E7 -6.61E7 -3.56 -4.8974 -0.9996 3635483 CMLD5_000261 CO[C@H]1[C@H](C)/C(=C/CC(=O)OC)/c2ccc3OCOc3c12 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N06 compound treatment 9.1170401E7 -6550000.0 -0.34 8.7232535E7 -8810000.0 -0.47 -0.5727 -0.9856 3635485 CMLD5_000262 CC(=O)C([C@H](NC(=O)OCC=C)c1cccc(c1)C(F)(F)F)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N07 compound treatment 8.7929384E7 -9790000.0 -0.5 8.3055415E7 -1.3E7 -0.7 -0.8492 -0.9867 3635487 CMLD5_000263 COC(=O)C1(C/C=C\C/C=C\c2ccccc2C1C[N+](=O)[O-])C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N08 compound treatment 8.5470049E7 -1.22E7 -0.63 8.1311057E7 -1.47E7 -0.79 -1.0048 -0.9933 3635489 CMLD5_000264 CC(C)CCNC(=O)[C@H](C)[C@@H]1CC[C@@]2(C)C=CC(=O)C(=C2[C@H]1O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N09 mock treatment 8.9858018E7 -7860000.0 -0.4 8.4079559E7 -1.2E7 -0.64 -0.7403 -0.9744 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N10 mock treatment 8.7665683E7 -1.01E7 -0.52 7.9681421E7 -1.64E7 -0.88 -0.9873 -0.9673 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N11 compound treatment 2.6940534E7 -7.08E7 -3.63 2.7706609E7 -6.83E7 -3.68 -5.1671 -1.0 3011353 CMLD5_000265 Oc1ccccc1C(=O)/C=C/c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N12 compound treatment 8.8717485E7 -9000000.0 -0.46 7.8329956E7 -1.77E7 -0.95 -1.0006 -0.9444 3635491 CMLD5_000266 CC(=C)C(=O)c1cccs1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N13 mock treatment 8.3524991E7 -1.42E7 -0.73 7.068598E7 -2.54E7 -1.37 -1.4799 -0.9565 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N14 mock treatment 8.5073744E7 -1.26E7 -0.65 7.1146406E7 -2.49E7 -1.34 -1.4062 -0.9444 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N15 compound treatment 3.5479737E7 -6.22E7 -3.19 3.5458142E7 -6.06E7 -3.26 -4.5625 -0.9999 3635492 CMLD5_000267 C/C(=C\C[Si](C)(C)C)/CC[C@H](O)C1=CCCCC1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N16 compound treatment 7.7445143E7 -2.03E7 -1.04 7.3429521E7 -2.26E7 -1.22 -1.5957 -0.9969 3635494 CMLD5_000268 C[C@H](OC(=O)C)C#C[Si](C)(C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N17 compound treatment 8.4533745E7 -1.32E7 -0.68 7.4498904E7 -2.15E7 -1.16 -1.2981 -0.9669 3635145 CMLD5_000269 CCOC(=O)C(CC=C)Nc1ccc(OC)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N18 compound treatment 8.5834836E7 -1.19E7 -0.61 7.9988125E7 -1.61E7 -0.86 -1.0419 -0.9853 3635496 CMLD5_000270 COC(=O)C(O)(CC=C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N19 compound treatment 8.5061458E7 -1.27E7 -0.65 8.2697876E7 -1.33E7 -0.72 -0.9668 -0.9987 3635497 CMLD5_000271 C[C@H]([C@@H](NC(=O)OCC=C)c1ccccc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N20 compound treatment 3.3221664E7 -6.45E7 -3.31 3.945317E7 -5.66E7 -3.05 -4.4922 -0.9992 3635499 CMLD5_000272 OC(CC=C)(/C=C/c1ccccc1)c2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N21 compound treatment 4.5101376E7 -5.26E7 -2.7 4.255613E7 -5.35E7 -2.88 -3.9435 -0.9995 3132532 CMLD5_000273 Nc1ccccc1C(=O)/C=C/c2ccc3OCOc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N22 compound treatment 7.6966926E7 -2.07E7 -1.06 7.252499E7 -2.35E7 -1.27 -1.6475 -0.9962 3635501 CMLD5_000274 O[C@@H](CCOC(c1ccccc1)(c2ccccc2)c3ccccc3)C4=CCCCC4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N23 compound treatment 7.3392822E7 -2.43E7 -1.25 7.2683454E7 -2.34E7 -1.26 -1.771 -1.0 3635502 CMLD5_000275 CCC(=O)C([C@H](CCc1ccccc1)NC(=O)OC)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 N24 compound treatment 1.01975929E8 4260000.0 0.22 1.0036449E8 4320000.0 0.23 0.3189 0.9995 3635504 CMLD5_000276 COC(=O)C1(C/C=C\C/C=C\c2ccccc2[C@@H]1C[N+](=O)[O-])C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O01 compound treatment 1.17062578E8 1.93E7 0.99 1.08205987E8 1.22E7 0.66 1.1643 0.9798 3635505 CMLD5_000277 COC(=O)N1C(CC(=O)C)c2ccccc2C=C1C3CC3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O02 compound treatment 8.1922015E7 -1.58E7 -0.81 8.2600661E7 -1.34E7 -0.72 -1.0843 -0.9984 3635506 CMLD5_000278 CC(C)OC(=O)[C@H]1O[C@H](CCCCOCc2ccccc2)[C@@H](C)C=C1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O03 compound treatment 7.6098778E7 -2.16E7 -1.11 6.9159921E7 -2.69E7 -1.45 -1.8071 -0.9913 3635508 CMLD5_000279 Cc1ccc(cc1)C(=O)OC[C@H]2O[C@H](Cl)C[C@@H]2OC(=O)c3ccc(C)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O04 compound treatment 9.8642459E7 926000.0 0.05 9.4712502E7 -1330000.0 -0.07 -0.0171 -0.199 3635509 CMLD5_000280 Cc1cc(O)cc(O)c1C(=O)OC2(C)C(=O)C=C3C=C(OC=C3C2=O)/C=C/CO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O05 compound treatment 9.7522301E7 -195000.0 -0.01 9.7598911E7 1560000.0 0.08 0.0522 0.6186 3635271 CMLD5_000281 COCC1=C2[C@H](CC([C@@H](C[N+](=O)[O-])c3ccccc23)(C(=O)OC)C(=O)OC)n4n(C1)c(=O)n(c5ccccc5)c4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O06 compound treatment 9.3615155E7 -4100000.0 -0.21 9.4003489E7 -2040000.0 -0.11 -0.2263 -0.9541 3635511 CMLD5_000282 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@H](CC(C)C)NC(=O)OCC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O07 compound treatment 8.7270307E7 -1.04E7 -0.54 9.0863703E7 -5180000.0 -0.28 -0.5758 -0.9538 3635513 CMLD5_000283 COC(=O)C1(Cc2conc2[C@H]1c3ccccc3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O08 compound treatment 8.3244456E7 -1.45E7 -0.74 8.4310246E7 -1.17E7 -0.63 -0.9712 -0.9968 3635515 CMLD5_000284 O=C1N[C@H](Cc2ccccc2)C(=O)N1Cc3cccc4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O09 compound treatment 8.4857757E7 -1.29E7 -0.66 7.2251995E7 -2.38E7 -1.28 -1.3719 -0.9523 3635517 CMLD5_000285 C[C@@H]1C[C@@](C)(C=C1c2ccc3ccccc3c2)C(=O)c4ccc5ccccc5c4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O10 compound treatment 8.8675485E7 -9040000.0 -0.46 8.6050191E7 -9990000.0 -0.54 -0.7082 -0.9972 3011264 CMLD5_000286 CCOC(=O)CC(CC(=O)C)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O11 mock treatment 8.5347328E7 -1.24E7 -0.63 8.4348311E7 -1.17E7 -0.63 -0.8936 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O12 mock treatment 8.261625E7 -1.51E7 -0.77 7.8185831E7 -1.79E7 -0.96 -1.2272 -0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O13 compound treatment 2.7181442E7 -7.05E7 -3.62 2.6462043E7 -6.96E7 -3.75 -5.2058 -0.9998 3635519 CMLD5_000287 CC(=O)C(=C)C(O)c1ccc(cc1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O14 compound treatment 7.1946959E7 -2.58E7 -1.32 6.0716033E7 -3.53E7 -1.9 -2.2791 -0.9841 3635520 CMLD5_000288 C/C(=C\C[Si](C)(C)C)/CCC=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O15 compound treatment 7.4682637E7 -2.3E7 -1.18 7.9330928E7 -1.67E7 -0.9 -1.4711 -0.991 3635522 CMLD5_000289 CC(C)(C(O)c1ccc(cc1)[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O16 compound treatment 7.8344831E7 -1.94E7 -0.99 7.8905279E7 -1.71E7 -0.92 -1.3546 -0.9993 1019983 CMLD5_000290 CC(O)(CC=C)c1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O17 compound treatment 7.6479371E7 -2.12E7 -1.09 8.308111E7 -1.3E7 -0.7 -1.2632 -0.9769 3635523 CMLD5_000291 COC(=O)N[C@@H](CCc1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O18 compound treatment 4.3647364E7 -5.41E7 -2.77 5.0788435E7 -4.53E7 -2.44 -3.6827 -0.9979 3635525 CMLD5_000292 COc1cccc(c1)c2coc3ccc(Br)cc3c2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O19 compound treatment 7.7124129E7 -2.06E7 -1.06 8.0251343E7 -1.58E7 -0.85 -1.3476 -0.9943 3635526 CMLD5_000293 COC(=O)N[C@H](C[N+](=O)[O-])c1cccc(C)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O20 compound treatment 8.0184681E7 -1.75E7 -0.9 7.9209626E7 -1.68E7 -0.91 -1.2763 -1.0 3635528 CMLD5_000294 COC(=O)NC(CCc1ccccc1)C(C(=O)OC)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O21 compound treatment 6.9141322E7 -2.86E7 -1.46 7.0017195E7 -2.6E7 -1.4 -2.0266 -0.9998 1913672 CMLD5_000295 [O-][N+](=O)c1cccc(/C=C/C(=O)c2ccccc2)c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O22 compound treatment 9.4407133E7 -3310000.0 -0.17 8.7376085E7 -8670000.0 -0.47 -0.4499 -0.9061 3635529 CMLD5_000296 OC(C1=CCCC1=O)c2ccc3OCOc3c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O23 compound treatment 9.6965699E7 -751000.0 -0.04 9.1352163E7 -4690000.0 -0.25 -0.2058 -0.8056 3635513 CMLD5_000297 COC(=O)C1(Cc2conc2[C@H]1c3ccccc3)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 O24 compound treatment 1.05082162E8 7370000.0 0.38 1.02132696E8 6090000.0 0.33 0.4988 0.9975 3635459 CMLD5_000298 COC(=O)C1(CC=CCc2ccccc2[C@@H]1C[N+](=O)[O-])C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P01 compound treatment 1.0720203E8 9490000.0 0.49 9.9621707E7 3580000.0 0.19 0.4801 0.918 3635530 CMLD5_000299 COC(=O)CC1N(C(=O)OC)C(=C(Cc2ccc3OCOc3c2)c4ccccc14)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P02 compound treatment 1.02233437E8 4520000.0 0.23 9.3616918E7 -2430000.0 -0.13 0.0713 0.2684 3635531 CMLD5_000300 COC(=O)C1=C(C)[C@H](O)[C@@H](C)[C@@](C)(O1)c2cc(OC)c(C)c(OC)c2COc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P03 compound treatment 1.06097726E8 8380000.0 0.43 9.5146706E7 -895000.0 -0.05 0.2696 0.6238 3635532 CMLD5_000301 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H](O)[C@H]1C)c2cc(OC)c(C)c(OC)c2O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P04 compound treatment 6.0718612E7 -3.7E7 -1.9 5.6552172E7 -3.95E7 -2.13 -2.8446 -0.9984 3635534 CMLD5_000302 COC(=O)[C@@]1(Cc2ccccc2c3ccco3)C=C[C@H](C)[C@H](N1C(=O)C(F)(F)F)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P05 compound treatment 5.8269774E7 -3.94E7 -2.02 6.1422589E7 -3.46E7 -1.86 -2.7479 -0.9992 3635536 CMLD5_000303 COC(=O)C1(CC(=CCc2ccccc2[C@@H]1C[N+](=O)[O-])C=C)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P06 compound treatment 1.01159729E8 3440000.0 0.18 9.350793E7 -2530000.0 -0.14 0.0283 0.1267 3635538 CMLD5_000304 COC(=O)/C(=C(/C)\NCc1ccccc1)/[C@@H](NC(=O)OCC=C)c2cccc(F)c2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P07 compound treatment 9.3189329E7 -4530000.0 -0.23 9.579617E7 -246000.0 -0.01 -0.1735 -0.7463 1026004 CMLD5_000305 COc1ccc2ccccc2c1c3c(OC)ccc4ccccc34 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P08 compound treatment 8.4943461E7 -1.28E7 -0.65 8.8100746E7 -7940000.0 -0.43 -0.7653 -0.9787 3635540 CMLD5_000306 C[C@@]12O[C@H]2[C@@H](O)C(=C(CO)[C@H]1O)Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P09 compound treatment 8.7806422E7 -9910000.0 -0.51 9.4611228E7 -1430000.0 -0.08 -0.4137 -0.8052 3635542 CMLD5_000307 COc1ccc(cc1)C(=O)C(=C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P10 compound treatment 8.3363033E7 -1.44E7 -0.74 8.562766E7 -1.04E7 -0.56 -0.9168 -0.991 3635543 CMLD5_000308 CC1(CC2(C)[C@@H](CC1=O)c3ccc(Br)cc3)C=C2/C=C/c4ccc(Br)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P11 mock treatment 7.9288894E7 -1.84E7 -0.94 8.9586314E7 -6460000.0 -0.35 -0.9137 -0.9078 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P12 mock treatment 8.3963864E7 -1.38E7 -0.7 7.223388E7 -2.38E7 -1.28 -1.405 -0.9603 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P13 compound treatment 7.9366828E7 -1.84E7 -0.94 6.988582E7 -2.62E7 -1.41 -1.661 -0.9807 3011405 CMLD5_000309 OC(CCc1ccccc1)C2=CCCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P14 compound treatment 7.43137E7 -2.34E7 -1.2 7.4875429E7 -2.12E7 -1.14 -1.6542 -0.9997 3635545 CMLD5_000310 C[C@@]1(CC[C@H](O)[C@@H]2[C@@H]1CCCC2=O)C=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P15 compound treatment 3.9695198E7 -5.8E7 -2.97 7.06717E7 -2.54E7 -1.37 -3.0688 -0.9377 3635547 CMLD5_000311 ClC1NC=Nc2c1ncn2CCC#N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P16 compound treatment 3.0338782E7 -6.74E7 -3.45 2.9366913E7 -6.67E7 -3.59 -4.9807 -0.9998 3635548 CMLD5_000312 FC(F)(F)c1cc(NC(=S)Nc2ccc3ccccc3c2)cc(c1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P17 compound treatment 8.1796788E7 -1.59E7 -0.82 8.1632638E7 -1.44E7 -0.78 -1.1257 -0.9997 3635549 CMLD5_000313 CC(O)(CCc1ccccc1)CC=C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P18 compound treatment 8.4132445E7 -1.36E7 -0.7 8.3418534E7 -1.26E7 -0.68 -0.973 -0.9999 3635550 CMLD5_000314 CCOC(=O)[C@](C)(CC=C)Nc1ccc(OC)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P19 compound treatment 8.1784554E7 -1.59E7 -0.82 8.2850485E7 -1.32E7 -0.71 -1.0797 -0.9976 3635552 CMLD5_000315 COC(=O)N[C@@H](/C=C/c1ccccc1)[C@@H](C)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P20 compound treatment 8.9328372E7 -8390000.0 -0.43 9.0823286E7 -5220000.0 -0.28 -0.5027 -0.9788 3635554 CMLD5_000316 CCOC(=O)C(C)(CC=C)NCc1ccccc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P21 compound treatment 4.9845092E7 -4.79E7 -2.45 3.9676591E7 -5.64E7 -3.04 -3.8812 -0.9944 3635555 CMLD5_000317 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc(cc2)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P22 compound treatment 8.9866819E7 -7850000.0 -0.4 8.6435087E7 -9610000.0 -0.52 -0.6503 -0.9923 3635557 CMLD5_000318 C[C@]1(C[C@]2(C)[C@@H](CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P23 compound treatment 1.06261783E8 8540000.0 0.44 1.00902177E8 4860000.0 0.26 0.4947 0.9697 3635536 CMLD5_000319 COC(=O)C1(CC(=CCc2ccccc2[C@@H]1C[N+](=O)[O-])C=C)C(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2413 P24 compound treatment 1.06063768E8 8350000.0 0.43 1.04649293E8 8610000.0 0.46 0.6302 0.9992 3635559 CMLD5_000320 COC(=O)C12CC3=C[C@H](CC3=O)Cc4ccccc4[C@@H]2CNC1=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A01 compound treatment 1.27189307E8 2.81E7 1.44 1.29888677E8 2.22E7 1.19 1.8631 0.9956 3623416 BCB05_000001 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccc(F)cc3F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A02 compound treatment 1.20524105E8 2.15E7 1.1 1.23305654E8 1.56E7 0.84 1.3709 0.991 3623418 BCB05_000002 COc1ccc(cc1)c2nc3c(=O)[nH]c4ccccc4c3o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A03 compound treatment 1.20608041E8 2.15E7 1.1 1.23337456E8 1.56E7 0.84 1.3752 0.9909 3623419 BCB05_000003 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(F)cc3F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A04 compound treatment 1.27647483E8 2.86E7 1.47 1.30965327E8 2.32E7 1.25 1.9207 0.9969 3623421 BCB05_000004 COc1ccc(cc1)c2nc3c(=O)n(Cc4ccccc4)c5ccccc5c3o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A05 compound treatment 1.13549531E8 1.45E7 0.74 1.1690078E8 9170000.0 0.49 0.8743 0.9804 3623422 BCB05_000005 CCCCCCC(=C)/C=C/C(O)CCCCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A06 compound treatment 1.15358195E8 1.63E7 0.84 1.14361483E8 6630000.0 0.36 0.8431 0.9281 3623424 BCB05_000006 COc1ccc(cc1)c2nc3c(=O)n(C)c4ccccc4c3o2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A07 compound treatment 1.17878428E8 1.88E7 0.96 1.28608043E8 2.09E7 1.12 1.4769 0.9971 3623425 BCB05_000007 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccccc3Cl 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A08 compound treatment 1.24474523E8 2.54E7 1.3 1.271887E8 1.95E7 1.05 1.6619 0.9942 3623427 BCB05_000008 CCCCCn1c(=O)c2nc(oc2c3ccccc13)c4ccc(OC)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A09 compound treatment 3.8866417E7 -6.02E7 -3.09 3.3887892E7 -7.38E7 -3.98 -4.9933 -0.9921 3623428 BCB05_000009 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A10 compound treatment 1.15378325E8 1.63E7 0.84 1.21458133E8 1.37E7 0.74 1.1141 0.9981 3623430 BCB05_000010 CCCCCCCCCn1c(=O)c2nc(oc2c3ccccc13)c4ccc(OC)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A11 compound treatment 9.6147957E7 -2910000.0 -0.15 8.6359333E7 -2.14E7 -1.15 -0.9194 -0.7922 3623431 BCB05_000011 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc(Cl)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A12 compound treatment 1.12750923E8 1.37E7 0.7 1.10295281E8 2560000.0 0.14 0.5938 0.8304 3623433 BCB05_000012 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N=C5SCc6ccccc6C(=O)N45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A13 mock treatment 1.15149315E8 1.61E7 0.82 1.22243224E8 1.45E7 0.78 1.1357 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A14 mock treatment 1.09283928E8 1.02E7 0.52 1.10697947E8 2970000.0 0.16 0.4835 0.8826 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A15 compound treatment 1.03899984E8 4840000.0 0.25 1.06847934E8 -883000.0 -0.05 0.1418 0.5613 3623435 BCB05_000013 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A16 compound treatment 1.17195215E8 1.81E7 0.93 1.2316093E8 1.54E7 0.83 1.2448 0.9984 3623436 BCB05_000014 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N=C5Sc6ccc(cc6C(=O)N45)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A17 compound treatment 1.00513141E8 1450000.0 0.07 9.9986447E7 -7740000.0 -0.42 -0.2423 -0.5719 3623438 BCB05_000015 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A18 compound treatment 1.18921687E8 1.99E7 1.02 1.26330167E8 1.86E7 1.0 1.428 1.0 3623440 BCB05_000016 C[C@@]1(Oc2ccccc2[C@@H]3[C@H]1CO)N(CC=C)C(=S)N3C(=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A19 compound treatment 1.04460558E8 5400000.0 0.28 1.08336046E8 605000.0 0.03 0.2187 0.785 3623442 BCB05_000017 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A20 compound treatment 6.2581196E7 -3.65E7 -1.87 6.2992303E7 -4.47E7 -2.41 -3.0256 -0.9921 3623443 BCB05_000018 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=S)N2C)[C@@H]4CO)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A21 compound treatment 5.099431E7 -4.81E7 -2.46 4.5858254E7 -6.19E7 -3.33 -4.098 -0.989 3623445 BCB05_000019 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A22 compound treatment 1.06905697E8 7840000.0 0.4 1.01602675E8 -6130000.0 -0.33 0.051 0.098 3623447 BCB05_000020 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=O)N2C)[C@@H]4CO[Si](C)(C)C(C)(C)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A23 compound treatment 1.1528796E8 1.62E7 0.83 1.15988842E8 8260000.0 0.44 0.9025 0.957 3623449 BCB05_000021 CCCCCCC1=C[C@@H]2[C@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 A24 compound treatment 1.31477394E8 3.24E7 1.66 1.11446408E8 3720000.0 0.2 1.3163 0.7866 3623450 BCB05_000022 COc1ccc(COC[C@]2(NC(=S)N([C@H]3[C@H]2CO[Si](C)(C)C(C)(C)C)C(=O)c4ccccc4)Oc5ccccc35)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B01 compound treatment 2.6859364E7 -7.22E7 -3.7 2.6735157E7 -8.1E7 -4.36 -5.7008 -0.9967 3623452 BCB05_000023 CCOC(=O)N1CCN(CC1)/[N+](=N/Oc2cc(O\N=[N+](/[O-])\N3CCN(CC3)C(=O)OCC)c(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B02 compound treatment 1.10122552E8 1.11E7 0.57 1.12833661E8 5100000.0 0.27 0.5952 0.9447 3623454 BCB05_000024 CCN(CC)/[N+](=N/O[C@H]1C[C@@H](O)[C@H](O)C(CO)O1)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B03 compound treatment 2.5999558E7 -7.31E7 -3.74 2.5765312E7 -8.2E7 -4.41 -5.7689 -0.9967 3623456 BCB05_000025 CCOC(=O)N1CCN(CC1)/[N+](=N/Oc2cc(F)c(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B04 compound treatment 1.08743619E8 9680000.0 0.5 1.05560189E8 -2170000.0 -0.12 0.2683 0.5262 3623458 BCB05_000026 CCN(CC)/[N+](=N/O[C@H]1OC(CO)[C@@H](O)[C@H](O)[C@@H]1O)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B05 compound treatment 8.7956021E7 -1.11E7 -0.57 9.0344827E7 -1.74E7 -0.94 -1.0645 -0.9715 3623460 BCB05_000027 CCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccnc(Cl)n2)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B06 compound treatment 1.00860974E8 1800000.0 0.09 1.01208076E8 -6520000.0 -0.35 -0.1831 -0.5043 3623462 BCB05_000028 CN(C)S(=O)(=O)O/N=[N+](\[O-])/N1CCC[C@H]1C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B07 compound treatment 1.07950161E8 8890000.0 0.46 1.13918762E8 6190000.0 0.33 0.5578 0.9882 3623464 BCB05_000029 CCN(CC)/[N+](=N/Oc1ccc(cc1C(F)(F)F)[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B08 compound treatment 1.08017564E8 8960000.0 0.46 1.14742597E8 7010000.0 0.38 0.5916 0.9953 3623466 BCB05_000030 COCO/N=[N+](\[O-])/N1CCC[C@H]1C(=O)OCOC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B09 compound treatment 1.03109819E8 4050000.0 0.21 1.18857691E8 1.11E7 0.6 0.5704 0.8996 3623468 BCB05_000031 CCN(CC)/[N+](=N/Oc1ccc(cc1)[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B10 compound treatment 1.03198107E8 4140000.0 0.21 1.09345856E8 1620000.0 0.09 0.2114 0.9226 3623470 BCB05_000032 CCO/N=[N+](\[O-])/N1CCC[C@H]1C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B11 compound treatment 1.02534826E8 3470000.0 0.18 1.01982466E8 -5750000.0 -0.31 -0.093 -0.2604 3623472 BCB05_000033 CCN(CC)/[N+](=N/Oc1ccc(cn1)[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B12 compound treatment 9.959901E7 538000.0 0.03 1.11892083E8 4160000.0 0.22 0.178 0.7882 3623474 BCB05_000034 CCO/N=[N+](\[O-])/N1CCC[C@H]1C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B13 mock treatment 1.03492755E8 4430000.0 0.23 1.03367053E8 -4360000.0 -0.23 -0.0055 -0.017 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B14 mock treatment 1.01341714E8 2280000.0 0.12 1.04966918E8 -2760000.0 -0.15 -0.0226 -0.1193 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B15 compound treatment 8.4995284E7 -1.41E7 -0.72 8.2732563E7 -2.5E7 -1.35 -1.4616 -0.9572 3623476 BCB05_000035 CN(C)/[N+](=N/Oc1cc(N(C)c2ccccc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B16 compound treatment 8.8944642E7 -1.01E7 -0.52 9.6935523E7 -1.08E7 -0.58 -0.7777 -0.9984 3623478 BCB05_000036 CN(C)S(=O)(=O)O/N=[N+](\[O-])/N1CCC[C@H]1C(=O)ON2C(=O)CCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B17 compound treatment 9.807384E7 -987000.0 -0.05 9.5448297E7 -1.23E7 -0.66 -0.5035 -0.759 3623480 BCB05_000037 COc1ccc(cc1)N(C)c2cc(O/N=[N+](\[O-])/N(C)C)c(cc2[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B18 compound treatment 9.8062259E7 -999000.0 -0.05 9.9379841E7 -8350000.0 -0.45 -0.3542 -0.7825 3623482 BCB05_000038 CC(=O)OCO/N=[N+](\[O-])/N1CCC[C@H]1C(=O)OCOC(=O)c2ccccc2OC(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B19 compound treatment 9.6477913E7 -2580000.0 -0.13 9.6774132E7 -1.1E7 -0.59 -0.5108 -0.8448 3623480 BCB05_000039 COc1ccc(cc1)N(C)c2cc(O/N=[N+](\[O-])/N(C)C)c(cc2[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B20 compound treatment 1.12714654E8 1.37E7 0.7 1.18536869E8 1.08E7 0.58 0.9063 0.9958 3623484 BCB05_000040 [O-]/[N+](=N\OC=C)/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B21 compound treatment 2.5881235E7 -7.32E7 -3.75 2.6593462E7 -8.11E7 -4.37 -5.7417 -0.9971 3623486 BCB05_000041 CCN(CC)/[N+](=N/Oc1cc(O\N=[N+](/[O-])\N(CC)CC)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B22 compound treatment 3.0812253E7 -6.82E7 -3.5 2.8968916E7 -7.88E7 -4.24 -5.4725 -0.9954 3623488 BCB05_000042 [O-][N+](=O)c1ccc(OC(=O)N2CCN(CC2)/[N+](=N/Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B23 compound treatment 1.12019403E8 1.3E7 0.66 1.12650842E8 4920000.0 0.26 0.657 0.9188 3623490 BCB05_000043 CCN(CC)/[N+](=N/Oc1ccccc1[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 B24 compound treatment 1.15758244E8 1.67E7 0.86 1.13668069E8 5940000.0 0.32 0.8312 0.9099 1073729 BCB05_000044 O=C1Cc2cc3OCOc3cc2C=C4CCCN41 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C01 compound treatment 1.05806304E8 6750000.0 0.35 1.07575454E8 -155000.0 -0.01 0.2385 0.6898 3623428 BCB05_000045 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C02 compound treatment 6.8497614E7 -3.06E7 -1.57 6.9040968E7 -3.87E7 -2.08 -2.5809 -0.9901 3623492 BCB05_000046 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N(C)C(=S)N4C(=O)c5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C03 compound treatment 3.3840919E7 -6.52E7 -3.34 2.9034127E7 -7.87E7 -4.24 -5.3603 -0.9931 3623494 BCB05_000047 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccc(F)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C04 compound treatment 8.4416704E7 -1.46E7 -0.75 8.1181131E7 -2.65E7 -1.43 -1.5417 -0.9547 3623495 BCB05_000048 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N(C)C(=O)N4C(=O)CC(=O)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C05 compound treatment 2.6482363E7 -7.26E7 -3.72 2.6351124E7 -8.14E7 -4.38 -5.7291 -0.9967 3623497 BCB05_000049 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cc(C)ccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C06 compound treatment 1.00827027E8 1770000.0 0.09 1.13145619E8 5410000.0 0.29 0.2702 0.885 3623499 BCB05_000050 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO[Si](C)(C)C(C)(C)C)N=C(SCC=C)N4C(=O)c5ccccc5)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C07 compound treatment 1.0768184E8 8620000.0 0.44 1.24089679E8 1.64E7 0.88 0.9354 0.9491 3623501 BCB05_000051 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cc(C)ccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C08 compound treatment 9.1971291E7 -7090000.0 -0.36 1.0187771E8 -5850000.0 -0.32 -0.4798 -0.9975 3623502 BCB05_000052 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2CO)N=C5SCc6ccccc6C(=O)N45)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C09 compound treatment 2.6021968E7 -7.3E7 -3.74 2.6382069E7 -8.13E7 -4.38 -5.7446 -0.9969 3623504 BCB05_000053 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cc(C)ccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C10 compound treatment 1.03452359E8 4390000.0 0.23 1.05750555E8 -1980000.0 -0.11 0.0837 0.3363 3623506 BCB05_000054 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccccc5)N=C6Sc7ccc(cc7C(=O)N46)[N+](=O)[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C11 mock treatment 1.03672945E8 4610000.0 0.24 1.10700602E8 2970000.0 0.16 0.2802 0.9819 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C12 mock treatment 1.05451771E8 6390000.0 0.33 1.07660755E8 -70000.0 0.0 0.2289 0.6989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C13 compound treatment 9.312667E7 -5930000.0 -0.3 8.5826483E7 -2.19E7 -1.18 -1.0491 -0.8613 3623508 BCB05_000055 CCCCCCC1=C[C@H](C(O)CCCCC)[C@H]2[C@@H](C1)C(=O)NC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C14 compound treatment 8.8945162E7 -1.01E7 -0.52 9.3453618E7 -1.43E7 -0.77 -0.9103 -0.9816 3623510 BCB05_000056 COc1ccc(COC[C@@]2(Oc3ccccc3[C@@H]4[C@H]2COC(=O)c5ccccc5)N=C6SCc7ccccc7C(=O)N46)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C15 mock treatment 9.9459762E7 399000.0 0.02 1.0210374E8 -5630000.0 -0.3 -0.1998 -0.6579 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C16 mock treatment 9.725811E7 -1800000.0 -0.09 9.9955786E7 -7770000.0 -0.42 -0.3614 -0.8429 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C17 compound treatment 8.8264473E7 -1.08E7 -0.55 1.00229502E8 -7500000.0 -0.4 -0.6769 -0.988 3623070 BCB05_000057 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C18 compound treatment 1.01605087E8 2540000.0 0.13 1.02633045E8 -5100000.0 -0.27 -0.1019 -0.3353 3623512 BCB05_000058 OC[C@@H]1[C@@H]2N3C(=O)c4cc(ccc4SC3=N[C@@]1(CO)Oc5ccccc25)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C19 compound treatment 2.6395666E7 -7.27E7 -3.72 2.6214818E7 -8.15E7 -4.39 -5.7375 -0.9967 3623514 BCB05_000059 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C20 compound treatment 8.690377E7 -1.22E7 -0.62 8.6959738E7 -2.08E7 -1.12 -1.2315 -0.9618 3623516 BCB05_000060 OC[C@@]1(Oc2ccccc2[C@@H]3[C@H]1COC(=O)c4ccccc4)N=C5Sc6ccc(cc6C(=O)N35)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C21 compound treatment 1.03308084E8 4250000.0 0.22 1.1003494E8 2300000.0 0.12 0.2417 0.9645 3623518 BCB05_000061 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C22 compound treatment 9.6488526E7 -2570000.0 -0.13 9.6743226E7 -1.1E7 -0.59 -0.5116 -0.844 3623519 BCB05_000062 OC[C@@]1(Oc2ccccc2[C@@H]3[C@H]1COC(=O)c4ccccc4)N=C5SCc6ccccc6C(=O)N35 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C23 compound treatment 1.06310748E8 7250000.0 0.37 1.02834783E8 -4900000.0 -0.26 0.0763 0.1675 3623521 BCB05_000063 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccccc3OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 C24 compound treatment 1.18736547E8 1.97E7 1.01 1.2056298E8 1.28E7 0.69 1.2017 0.983 3623523 BCB05_000064 OC[C@@H]1[C@@H]2N3C(=N[C@@]1(CO)Oc4ccccc24)SCc5ccccc5C3=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D01 compound treatment 1.0732886E8 8270000.0 0.42 1.11539823E8 3810000.0 0.21 0.4447 0.9445 3623525 BCB05_000065 CCN(CC)/[N+](=N/Oc1ccnc(SC)n1)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D02 compound treatment 3.9383512E7 -5.97E7 -3.06 3.7984028E7 -6.97E7 -3.76 -4.8186 -0.9948 3623527 BCB05_000066 CC(C)[Si](OCCOc1ccc(cc1)c2noc3CCCNCCc4cc5OCOc5cc4-c23)(C(C)C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D03 compound treatment 1.06313791E8 7250000.0 0.37 1.11674189E8 3940000.0 0.21 0.413 0.9647 3623528 BCB05_000067 CCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D04 compound treatment 9.3916842E7 -5140000.0 -0.26 1.00821635E8 -6910000.0 -0.37 -0.4495 -0.9858 3623530 BCB05_000068 COc1ccc(cc1)c2noc3CCCNCCc4cc5OCOc5cc4-c23 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D05 compound treatment 9.5053018E7 -4010000.0 -0.21 1.08420023E8 689000.0 0.04 -0.119 -0.5701 3623531 BCB05_000069 CN(C)/[N+](=N/Oc1cc(Nc2cccc(c2)C(=O)O)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D06 mock treatment 1.08984313E8 9920000.0 0.51 1.15884262E8 8150000.0 0.44 0.6701 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D07 compound treatment 2.564776E7 -7.34E7 -3.76 2.5679163E7 -8.21E7 -4.42 -5.785 -0.9968 3623533 BCB05_000070 COC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D08 mock treatment 1.04927782E8 5870000.0 0.3 1.15189379E8 7460000.0 0.4 0.4966 0.9898 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D09 compound treatment 2.5698201E7 -7.34E7 -3.76 2.5987489E7 -8.17E7 -4.4 -5.7714 -0.9969 3623535 BCB05_000071 CCCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D10 mock treatment 9.6879543E7 -2180000.0 -0.11 1.10339355E8 2610000.0 0.14 0.0203 0.1129 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D11 mock treatment 9.972536E7 664000.0 0.03 1.12673804E8 4940000.0 0.27 0.2123 0.7911 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D12 mock treatment 1.06801626E8 7740000.0 0.4 1.1154592E8 3820000.0 0.21 0.4258 0.9531 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D13 compound treatment 2.6154773E7 -7.29E7 -3.74 2.6403673E7 -8.13E7 -4.38 -5.739 -0.9969 3623537 BCB05_000072 CCOC(=O)N1CCCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D14 mock treatment 9.7114094E7 -1950000.0 -0.1 1.06084065E8 -1650000.0 -0.09 -0.1333 -0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D15 mock treatment 9.9539608E7 479000.0 0.02 1.04718864E8 -3010000.0 -0.16 -0.0973 -0.5934 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D16 mock treatment 1.03886722E8 4830000.0 0.25 1.14582545E8 6850000.0 0.37 0.4358 0.9811 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D17 compound treatment 9.025636E7 -8800000.0 -0.45 9.1989548E7 -1.57E7 -0.85 -0.9185 -0.9564 3623539 BCB05_000073 CN(C)/[N+](=N/Oc1cc(Nc2ccc(cc2)C(=O)O)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D18 mock treatment 1.02459719E8 3400000.0 0.17 1.10525541E8 2790000.0 0.15 0.2296 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D19 compound treatment 1.00945487E8 1880000.0 0.1 1.06019535E8 -1710000.0 -0.09 0.0031 0.0235 3623541 BCB05_000074 CN(C)/[N+](=N/Oc1cc(N(C)c2cccc(c2)C(=O)O)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D20 mock treatment 9.8639241E7 -422000.0 -0.02 1.06875049E8 -856000.0 -0.05 -0.0479 -0.9404 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D21 compound treatment 2.6025528E7 -7.3E7 -3.74 2.5999122E7 -8.17E7 -4.4 -5.7591 -0.9968 3623543 BCB05_000075 CN(C)/[N+](=N/Oc1cc(F)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D22 mock treatment 1.0134087E8 2280000.0 0.12 1.07260383E8 -470000.0 -0.03 0.0647 0.5413 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D23 compound treatment 8.2790974E7 -1.63E7 -0.83 8.3482637E7 -2.42E7 -1.31 -1.513 -0.9765 3623545 BCB05_000076 CN(C)/[N+](=N/Oc1cc(O)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 D24 mock treatment 1.1596429E8 1.69E7 0.87 1.19446196E8 1.17E7 0.63 1.0587 0.9879 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E01 mock treatment 1.10806807E8 1.17E7 0.6 1.13194468E8 5460000.0 0.29 0.6337 0.9458 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E02 mock treatment 1.0118222E8 2120000.0 0.11 1.03623168E8 -4110000.0 -0.22 -0.0795 -0.3227 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E03 compound treatment 1.10773616E8 1.17E7 0.6 1.17962359E8 1.02E7 0.55 0.8141 0.9991 3623547 BCB05_000077 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cccc(OC)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E04 compound treatment 7.9297708E7 -1.98E7 -1.01 7.8715185E7 -2.9E7 -1.56 -1.8211 -0.978 3623549 BCB05_000078 COc1ccc(COC[C@]2(Oc3ccccc3[C@H]4NC(=S)N2C)[C@@H]4CO[Si](C)(C)C(C)(C)C)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E05 compound treatment 8.8286911E7 -1.08E7 -0.55 9.7525523E7 -1.02E7 -0.55 -0.7791 -1.0 3623551 BCB05_000079 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccc(Oc4ccccc4)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E06 compound treatment 1.09944212E8 1.09E7 0.56 1.20640905E8 1.29E7 0.7 0.886 0.994 3623553 BCB05_000080 OCC1O[C@@H](O/N=[N+](\[O-])/N2CCCC2)[C@H](O)[C@@H](O)[C@@H]1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E07 compound treatment 2.6198011E7 -7.29E7 -3.73 2.5753844E7 -8.2E7 -4.41 -5.7622 -0.9965 3623555 BCB05_000081 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(Oc4ccccc4)cc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E08 compound treatment 1.00408929E8 1350000.0 0.07 1.12542627E8 4810000.0 0.26 0.2321 0.8654 3623557 BCB05_000082 OCC1O[C@H](O/N=[N+](\[O-])/N2CCCC2)[C@@H](O)[C@@H](O)[C@@H]1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E09 mock treatment 9.9793131E7 732000.0 0.04 1.11001553E8 3270000.0 0.18 0.1511 0.8389 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E10 mock treatment 9.783446E7 -1230000.0 -0.06 1.10984792E8 3250000.0 0.18 0.0795 0.4268 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E11 compound treatment 2.6101733E7 -7.3E7 -3.74 2.5746518E7 -8.2E7 -4.41 -5.7659 -0.9966 3623558 BCB05_000083 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccc(C)cc3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E12 compound treatment 9.9654473E7 594000.0 0.03 1.05508784E8 -2220000.0 -0.12 -0.0631 -0.5111 3623560 BCB05_000084 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)C(CO)O[C@H]1O/N=[N+](\[O-])/N2CCCC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E13 compound treatment 1.03280345E8 4220000.0 0.22 1.07196104E8 -535000.0 -0.03 0.1326 0.6076 3623562 BCB05_000085 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3ccc(C)cc3C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E14 compound treatment 8.5742641E7 -1.33E7 -0.68 9.3469321E7 -1.43E7 -0.77 -1.0257 -0.9983 3623563 BCB05_000086 CC(=O)Oc1ccccc1C(=O)OCO/N=[N+](\[O-])/N2CCCC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E15 compound treatment 2.586529E7 -7.32E7 -3.75 2.6104448E7 -8.16E7 -4.4 -5.7609 -0.9969 3623565 BCB05_000087 CCCCCCC1=C[C@@H]2[C@@H](CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3cccc(OC)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E16 compound treatment 8.865471E7 -1.04E7 -0.53 9.533187E7 -1.24E7 -0.67 -0.8493 -0.9938 3623567 BCB05_000088 CN(C)/[N+](=N/OCOC(=O)c1ccccc1OC(=O)C)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E17 mock treatment 1.02059928E8 3000000.0 0.15 1.13292915E8 5560000.0 0.3 0.3205 0.9519 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E18 mock treatment 1.03611954E8 4550000.0 0.23 1.15680489E8 7950000.0 0.43 0.4676 0.9592 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E19 compound treatment 2.5814404E7 -7.32E7 -3.75 2.8416453E7 -7.93E7 -4.27 -5.6747 -0.9979 3623569 BCB05_000089 CCCCCCC1=C[C@H]([C@@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C2=O)c3cccc(OC)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E20 compound treatment 9.1320535E7 -7740000.0 -0.4 1.03575937E8 -4150000.0 -0.22 -0.4387 -0.9633 3623570 BCB05_000090 CC(=O)Oc1ccccc1C(=O)OCO/N=[N+](\[O-])/N2CCC[C@H]2C(=O)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E21 compound treatment 8.7771377E7 -1.13E7 -0.58 1.01787804E8 -5940000.0 -0.32 -0.6354 -0.961 3623572 BCB05_000091 CCCCCCC1=C[C@@H]2C(CCCCC)OC(=O)[C@@H]2[C@@H](C1)C(=O)Nc3ccc(F)c(F)c3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E22 compound treatment 1.06567461E8 7510000.0 0.38 1.13997283E8 6270000.0 0.34 0.5107 0.9979 3623574 BCB05_000092 CCN(CC)/[N+](=N/O[C@H]1CCCCO1)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E23 compound treatment 1.1534042E8 1.63E7 0.83 1.24143303E8 1.64E7 0.88 1.2149 0.9996 3623576 BCB05_000093 C[C@@H](O)[C@H]1C=C2C(C)(C)CCC[C@@]2(C)[C@@H]3[C@H]1C(=O)N(C3=O)c4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 E24 compound treatment 1.07181759E8 8120000.0 0.42 1.06019551E8 -1710000.0 -0.09 0.2291 0.5375 3623578 BCB05_000094 CCN(CC)/[N+](=N/OCOC(=O)C)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F01 mock treatment 1.13860895E8 1.48E7 0.76 1.12485062E8 4750000.0 0.26 0.7174 0.8961 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F02 mock treatment 1.13098619E8 1.4E7 0.72 1.20307544E8 1.26E7 0.68 0.9876 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F03 compound treatment 6.5281712E7 -3.38E7 -1.73 6.8909663E7 -3.88E7 -2.09 -2.7024 -0.9956 3623579 BCB05_000095 CN(C)/[N+](=N/Oc1cc(OC(=O)c2ccc(NC(=O)C)cc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F04 mock treatment 9.9819065E7 758000.0 0.04 1.12012133E8 4280000.0 0.23 0.1905 0.8148 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F05 compound treatment 2.8308156E7 -7.08E7 -3.63 2.7725863E7 -8.0E7 -4.31 -5.6106 -0.9963 3623581 BCB05_000096 CN(C)/[N+](=N/Oc1cc(OC(=O)c2ccc(cc2)N(C)C)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F06 mock treatment 1.00945062E8 1880000.0 0.1 1.10071355E8 2340000.0 0.13 0.1574 0.9913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F07 compound treatment 1.04935301E8 5870000.0 0.3 1.16581275E8 8850000.0 0.48 0.5499 0.9755 3623583 BCB05_000097 CN(C)/[N+](=N/Oc1cc(OC(=O)c2ccc(cc2)[N+](=O)[O-])c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F08 mock treatment 9.7320921E7 -1740000.0 -0.09 1.10514165E8 2780000.0 0.15 0.0429 0.2461 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F09 mock treatment 1.02496719E8 3440000.0 0.18 1.12402543E8 4670000.0 0.25 0.3024 0.9848 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F10 mock treatment 9.6724878E7 -2340000.0 -0.12 1.10391753E8 2660000.0 0.14 0.0167 0.0893 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F11 compound treatment 9.6535467E7 -2530000.0 -0.13 1.08310247E8 579000.0 0.03 -0.0695 -0.5217 3623585 BCB05_000098 CN(C)/[N+](=N/Oc1cc(OC(=O)c2cccnc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F12 mock treatment 9.7579658E7 -1480000.0 -0.08 1.10279992E8 2550000.0 0.14 0.0434 0.2766 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F13 compound treatment 8.9636914E7 -9420000.0 -0.48 9.9827809E7 -7900000.0 -0.43 -0.6425 -0.998 3623587 BCB05_000099 CN(C)/[N+](=N/Oc1cc(OC(=O)c2ccccc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F14 mock treatment 9.9605389E7 544000.0 0.03 1.09321801E8 1590000.0 0.09 0.0803 0.8913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F15 compound treatment 2.5884853E7 -7.32E7 -3.75 2.5913935E7 -8.18E7 -4.41 -5.7674 -0.9968 3623589 BCB05_000100 CN(C)/[N+](=N/Oc1cc(Oc2ccc(NC(=O)C)cc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F16 mock treatment 9.7533784E7 -1530000.0 -0.08 1.03327547E8 -4400000.0 -0.24 -0.223 -0.8931 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F17 mock treatment 9.8710984E7 -350000.0 -0.02 1.13307938E8 5580000.0 0.3 0.1997 0.6637 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F18 mock treatment 1.01436753E8 2380000.0 0.12 1.11163626E8 3430000.0 0.18 0.2168 0.9795 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F19 compound treatment 7.9681063E7 -1.94E7 -0.99 9.7143802E7 -1.06E7 -0.57 -1.1055 -0.9653 3623591 BCB05_000101 CN(C)/[N+](=N/Oc1cc(OC(=O)c2ccccc2OC(=O)C)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F20 mock treatment 1.03401803E8 4340000.0 0.22 1.11524841E8 3790000.0 0.2 0.3018 0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F21 compound treatment 9.9595901E7 535000.0 0.03 1.07082703E8 -648000.0 -0.03 -0.0053 -0.1192 3623593 BCB05_000102 CC(C)Cc1ccc(cc1)C(C)C(=O)Oc2cc(O/N=[N+](\[O-])/N(C)C)c(cc2[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F22 mock treatment 9.905936E7 -1550.0 0.0 1.07880465E8 150000.0 0.01 0.0056 0.7001 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F23 compound treatment 9.1644688E7 -7420000.0 -0.38 9.868611E7 -9040000.0 -0.49 -0.6132 -0.9925 3623595 BCB05_000103 CN(C)/[N+](=N/Oc1cc(OS(=O)(=O)c2ccc(NC(=O)C)cc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 F24 mock treatment 1.17369442E8 1.83E7 0.94 1.17591058E8 9860000.0 0.53 1.039 0.9636 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G01 compound treatment 1.00417434E8 1360000.0 0.07 9.3609176E7 -1.41E7 -0.76 -0.4886 -0.6398 3623067 BCB05_000104 CCCCCCC1=C[C@H]([C@H](O)CCCCC)[C@H]2[C@@H](C1)C(=O)N(C)C2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G02 compound treatment 9.8298258E7 -763000.0 -0.04 9.7912923E7 -9820000.0 -0.53 -0.4015 -0.7573 3623597 BCB05_000105 CC(=O)OCO/N=[N+](\[O-])/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G03 mock treatment 1.05393172E8 6330000.0 0.32 1.12930704E8 5200000.0 0.28 0.4275 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G04 mock treatment 1.06312681E8 7250000.0 0.37 1.10934521E8 3200000.0 0.17 0.3848 0.9391 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G05 compound treatment 1.02120518E8 3060000.0 0.16 1.09773152E8 2040000.0 0.11 0.1887 0.9849 3623599 BCB05_000106 CCCCCCC1=C[C@H](CC(O)c2ccccc2)[C@H]3[C@@H](C1)C(=O)N(C3=O)c4ccccc4OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G06 compound treatment 1.05653623E8 6590000.0 0.34 1.16942271E8 9210000.0 0.5 0.5897 0.9825 3623601 BCB05_000107 CO/N=[N+](\[O-])/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G07 compound treatment 9.0486025E7 -8570000.0 -0.44 1.03756067E8 -3970000.0 -0.21 -0.4621 -0.9453 3623603 BCB05_000108 CCCCCCC1=C[C@H](CC(O)c2ccccc2)[C@H]3[C@@H](C1)C(=O)N(C3=O)c4ccc(F)cc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G08 compound treatment 1.03570107E8 4510000.0 0.23 1.13088507E8 5360000.0 0.29 0.3674 0.994 3623605 BCB05_000109 CCO/N=[N+](\[O-])/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G09 compound treatment 9.3435326E7 -5630000.0 -0.29 1.04097946E8 -3630000.0 -0.2 -0.3422 -0.9821 3623607 BCB05_000110 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G10 compound treatment 1.00888509E8 1830000.0 0.09 1.11208475E8 3480000.0 0.19 0.1987 0.9487 3623609 BCB05_000111 [O-]/[N+](=N\OCCBr)/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G11 compound treatment 1.01942247E8 2880000.0 0.15 1.10125031E8 2390000.0 0.13 0.1956 0.9977 3623607 BCB05_000112 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G12 compound treatment 9.5978733E7 -3080000.0 -0.16 1.02741726E8 -4990000.0 -0.27 -0.3017 -0.9679 3623611 BCB05_000113 CO/N=[N+](\[O-])/NC(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G13 compound treatment 9.9829072E7 768000.0 0.04 1.088811E8 1150000.0 0.06 0.0716 0.9761 3623612 BCB05_000114 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(Cc3cc(OC)c(OC)c(OC)c3)nc2c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G14 compound treatment 9.8069914E7 -991000.0 -0.05 1.08643586E8 913000.0 0.05 -0.0012 -0.0163 3623614 BCB05_000115 CO/N=[N+](\[O-])/N1CCCC(C1)C(=O)N 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G15 compound treatment 9.3692521E7 -5370000.0 -0.28 1.06162219E8 -1570000.0 -0.08 -0.2543 -0.8835 3623607 BCB05_000116 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G16 compound treatment 9.6456165E7 -2600000.0 -0.13 1.08584038E8 853000.0 0.05 -0.0619 -0.4385 3623616 BCB05_000117 NC(=O)C1CCCN(C1)/[N+](=N/OCCBr)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G17 compound treatment 9.8951839E7 -109000.0 -0.01 1.11350302E8 3620000.0 0.19 0.1339 0.6865 3623607 BCB05_000118 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G18 compound treatment 9.9776797E7 716000.0 0.04 1.13216638E8 5490000.0 0.3 0.2348 0.7889 3623618 BCB05_000119 CO/N=[N+](\[O-])/N(C)CC(C)O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G19 mock treatment 9.6780373E7 -2280000.0 -0.12 1.06660339E8 -1070000.0 -0.06 -0.1234 -0.9469 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G20 mock treatment 1.03760652E8 4700000.0 0.24 1.10616232E8 2890000.0 0.16 0.2802 0.9775 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G21 compound treatment 1.02648494E8 3590000.0 0.18 1.15857209E8 8130000.0 0.44 0.4395 0.9258 3623620 BCB05_000120 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(C)nc2c3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G22 compound treatment 1.06334533E8 7270000.0 0.37 1.11148505E8 3420000.0 0.18 0.3937 0.9471 3623622 BCB05_000121 CCN(CC)/[N+](=N/OC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G23 compound treatment 1.03215688E8 4150000.0 0.21 1.0475653E8 -2970000.0 -0.16 0.0373 0.1401 3623607 BCB05_000122 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 G24 compound treatment 1.11828502E8 1.28E7 0.65 1.116739E8 3940000.0 0.21 0.6129 0.8908 3623623 BCB05_000123 CCN(CC)/[N+](=N/OCCBr)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H01 compound treatment 2.7029808E7 -7.2E7 -3.69 2.7085254E7 -8.06E7 -4.34 -5.6813 -0.9967 3623625 BCB05_000124 CN(C)/[N+](=N/Oc1cc(O\N=[N+](/[O-])\N(C)C)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H02 mock treatment 1.08559616E8 9500000.0 0.49 1.16641329E8 8910000.0 0.48 0.6835 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H03 mock treatment 1.07061966E8 8000000.0 0.41 1.18307556E8 1.06E7 0.57 0.6927 0.987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H04 mock treatment 1.01117185E8 2060000.0 0.11 1.06469133E8 -1260000.0 -0.07 0.0265 0.2112 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H05 compound treatment 2.6366892E7 -7.27E7 -3.73 2.6115781E7 -8.16E7 -4.4 -5.7423 -0.9966 3623627 BCB05_000125 OC[C@@H]1CCCN1/[N+](=N/Oc2cc(O\N=[N+](/[O-])\N3CCC[C@H]3CO)c(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H06 mock treatment 1.03568603E8 4510000.0 0.23 1.1193377E8 4200000.0 0.23 0.3234 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H07 compound treatment 2.8088E7 -7.1E7 -3.64 3.1498197E7 -7.62E7 -4.11 -5.4749 -0.9982 3623629 BCB05_000126 CNc1ccc(cc1)C(=O)Oc2cc(O/N=[N+](\[O-])/N3CCC[C@H]3CO)c(cc2[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H08 mock treatment 9.7721227E7 -1340000.0 -0.07 1.08835626E8 1100000.0 0.06 -0.0065 -0.0713 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H09 compound treatment 8.8219692E7 -1.08E7 -0.56 9.850943E7 -9220000.0 -0.5 -0.744 -0.9984 3623631 BCB05_000127 OC(=O)[C@@H]1CCCN1/[N+](=N/Oc2cc(O\N=[N+](/[O-])\N3CCC[C@H]3C(=O)O)c(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H10 mock treatment 9.2489076E7 -6570000.0 -0.34 1.0761768E8 -113000.0 -0.01 -0.2425 -0.7198 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H11 compound treatment 2.6815189E7 -7.22E7 -3.7 2.6673151E7 -8.11E7 -4.37 -5.7048 -0.9966 3623633 BCB05_000128 CN(C)/[N+](=N/Oc1cc(Oc2cccc3C(=O)C=CC(=O)c23)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H12 mock treatment 9.6521192E7 -2540000.0 -0.13 1.06417724E8 -1310000.0 -0.07 -0.142 -0.9589 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H13 compound treatment 9.5322606E7 -3740000.0 -0.19 1.03495353E8 -4240000.0 -0.23 -0.2968 -0.9962 3623635 BCB05_000129 [O-][N+](=O)c1cc(ccc1O/N=[N+](\[O-])/N2CCN(CC2)c3ccccc3)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H14 mock treatment 9.8802839E7 -258000.0 -0.01 1.09151907E8 1420000.0 0.08 0.0448 0.5764 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H15 compound treatment 9.3814053E7 -5250000.0 -0.27 1.09898791E8 2170000.0 0.12 -0.1076 -0.367 3623637 BCB05_000130 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCCC2)nc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H16 mock treatment 9.5084803E7 -3980000.0 -0.2 1.05534276E8 -2200000.0 -0.12 -0.2277 -0.9665 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H17 compound treatment 6.652982E7 -3.25E7 -1.67 7.2268311E7 -3.55E7 -1.91 -2.5293 -0.9977 3623639 BCB05_000131 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCN(CC2)c3ccccc3)nc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H18 mock treatment 9.8237964E7 -823000.0 -0.04 1.08759906E8 1030000.0 0.06 0.0094 0.1345 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H19 mock treatment 9.9397098E7 336000.0 0.02 1.10778926E8 3050000.0 0.16 0.1283 0.7771 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H20 mock treatment 1.00395567E8 1330000.0 0.07 1.080021E8 271000.0 0.01 0.0587 0.8392 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H21 compound treatment 1.03023431E8 3960000.0 0.2 1.07407414E8 -323000.0 -0.02 0.1313 0.6441 3623641 BCB05_000132 CN(C)/[N+](=N/Oc1ccc(cn1)[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H22 mock treatment 1.02295653E8 3230000.0 0.17 1.10846401E8 3120000.0 0.17 0.2359 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H23 compound treatment 2.6900063E7 -7.22E7 -3.7 2.6702121E7 -8.1E7 -4.36 -5.7006 -0.9966 3623643 BCB05_000133 CNc1ccc(cc1)C(=O)Oc2cc(O/N=[N+](\[O-])/N(C)C)c(cc2[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 H24 mock treatment 1.10426035E8 1.14E7 0.58 1.15369689E8 7640000.0 0.41 0.7028 0.9855 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I01 compound treatment 1.10909826E8 1.18E7 0.61 1.08499747E8 769000.0 0.04 0.4587 0.7536 3623607 BCB05_000134 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I02 compound treatment 1.08266226E8 9210000.0 0.47 1.14334526E8 6600000.0 0.36 0.5851 0.9903 3623645 BCB05_000135 CO/N=[N+](\[O-])/N1CCCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I03 compound treatment 1.05813829E8 6750000.0 0.35 1.13431363E8 5700000.0 0.31 0.4618 0.9982 3623607 BCB05_000136 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I04 compound treatment 1.06303625E8 7240000.0 0.37 1.14981155E8 7250000.0 0.39 0.5386 0.9997 3623623 BCB05_000137 CCN(CC)/[N+](=N/OCCBr)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I05 mock treatment 1.04501278E8 5440000.0 0.28 1.06352573E8 -1380000.0 -0.07 0.1447 0.5014 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I06 mock treatment 1.01600668E8 2540000.0 0.13 1.08433503E8 703000.0 0.04 0.1188 0.8764 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I07 compound treatment 1.03310224E8 4250000.0 0.22 1.08982909E8 1250000.0 0.07 0.2017 0.8846 3623647 BCB05_000138 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(CCC3C(=O)Nc4ccccc34)nc2c5ccccc5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I08 compound treatment 9.6015196E7 -3050000.0 -0.16 1.05710343E8 -2020000.0 -0.11 -0.1873 -0.9844 3623649 BCB05_000139 CCN(CC)/[N+](=N/OCc1ccccc1)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I09 compound treatment 8.9613824E7 -9450000.0 -0.48 9.7828445E7 -9900000.0 -0.53 -0.7194 -0.9988 3623651 BCB05_000140 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4cc5ccccc5oc4=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I10 compound treatment 9.3887148E7 -5170000.0 -0.27 9.8555452E7 -9180000.0 -0.49 -0.5369 -0.9574 3623653 BCB05_000141 COCCN(C)/[N+](=N/OC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I11 compound treatment 9.6975023E7 -2090000.0 -0.11 1.05414027E8 -2320000.0 -0.12 -0.1638 -0.997 3623612 BCB05_000142 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(Cc3cc(OC)c(OC)c(OC)c3)nc2c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I12 compound treatment 9.4412025E7 -4650000.0 -0.24 1.07073487E8 -657000.0 -0.04 -0.1935 -0.8033 3623655 BCB05_000143 CC(C)N/[N+](=N/OCc1ccc(cc1)[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I13 compound treatment 8.4595177E7 -1.45E7 -0.74 9.451854E7 -1.32E7 -0.71 -1.0274 -0.9998 3623657 BCB05_000144 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4cccc5[nH]ccc45 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I14 compound treatment 9.3455321E7 -5610000.0 -0.29 1.08676723E8 946000.0 0.05 -0.1671 -0.5728 3623659 BCB05_000145 CO/N=[N+](\[O-])/NC1CCCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I15 compound treatment 9.754377E7 -1520000.0 -0.08 1.09412345E8 1680000.0 0.09 0.009 0.0758 3623661 BCB05_000146 CC[C@@H]1Cc2cc(nc(c3ccccc3)c2[Si](O1)(C(C)C)C(C)C)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I16 compound treatment 9.4213236E7 -4850000.0 -0.25 1.06242315E8 -1490000.0 -0.08 -0.2324 -0.8901 3623663 BCB05_000147 CC(C)N/[N+](=N/OCCBr)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I17 compound treatment 9.1634387E7 -7430000.0 -0.38 1.05376896E8 -2350000.0 -0.13 -0.3588 -0.8943 3623607 BCB05_000148 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I18 compound treatment 9.7361341E7 -1700000.0 -0.09 1.09578249E8 1850000.0 0.1 0.0088 0.0662 3623665 BCB05_000149 CC(C)N1CCON=[N+]1[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I19 compound treatment 1.06839568E8 7780000.0 0.4 1.18563804E8 1.08E7 0.58 0.6944 0.9828 3623666 BCB05_000150 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(CCOc3ccc(C)cc3)nc2c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I20 compound treatment 1.00438439E8 1380000.0 0.07 1.11125583E8 3390000.0 0.18 0.1792 0.9144 3623668 BCB05_000151 COCO/N=[N+](\[O-])/NC(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I21 mock treatment 9.9633814E7 573000.0 0.03 1.06801225E8 -930000.0 -0.05 -0.0146 -0.2521 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I22 mock treatment 9.9493492E7 433000.0 0.02 1.04794767E8 -2940000.0 -0.16 -0.0961 -0.6021 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I23 compound treatment 1.09485856E8 1.04E7 0.53 1.09291686E8 1560000.0 0.08 0.4372 0.8084 3623607 BCB05_000152 CC[C@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccccc3)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 I24 compound treatment 1.16096792E8 1.7E7 0.87 1.14224805E8 6490000.0 0.35 0.8647 0.9193 3623670 BCB05_000153 CO/N=[N+](\[O-])/N(C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J01 compound treatment 2.7001934E7 -7.21E7 -3.69 2.6812348E7 -8.09E7 -4.36 -5.6927 -0.9966 3623672 BCB05_000154 CCN(CC)C(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J02 mock treatment 1.05271474E8 6210000.0 0.32 1.14379533E8 6650000.0 0.36 0.4783 0.9983 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J03 compound treatment 2.6045902E7 -7.3E7 -3.74 2.5982689E7 -8.17E7 -4.4 -5.759 -0.9967 3623674 BCB05_000155 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCN(CC2)C(=O)c3cccnc3)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J04 mock treatment 1.02377259E8 3320000.0 0.17 1.05728106E8 -2000000.0 -0.11 0.0439 0.2182 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J05 mock treatment 1.02084295E8 3020000.0 0.15 1.05871897E8 -1860000.0 -0.1 0.0388 0.2103 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J06 mock treatment 1.00261904E8 1200000.0 0.06 1.08805632E8 1070000.0 0.06 0.0845 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J07 compound treatment 3.6461859E7 -6.26E7 -3.21 3.1606508E7 -7.61E7 -4.1 -5.1673 -0.9926 3623676 BCB05_000156 CC(C)Cc1ccc(cc1)C(C)C(=O)N2CCN(CC2)/[N+](=N/Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J08 compound treatment 8.5853697E7 -1.32E7 -0.68 9.9580886E7 -8150000.0 -0.44 -0.789 -0.978 3623678 BCB05_000157 COc1cc2CCN3CCC[C@H]4C(=NO[C@]43c2cc1OC)c5ccc(CO)o5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J09 compound treatment 2.6675317E7 -7.24E7 -3.71 2.6777657E7 -8.1E7 -4.36 -5.7059 -0.9968 3623680 BCB05_000158 CC(C)(C)OC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J10 compound treatment 8.2739164E7 -1.63E7 -0.84 9.2874845E7 -1.49E7 -0.8 -1.1572 -0.9998 3623682 BCB05_000159 OCc1ccc(o1)C2=NO[C@@]34[C@H]2CCN4CCc5cc6OCOc6cc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J11 compound treatment 2.6187202E7 -7.29E7 -3.73 2.6087206E7 -8.16E7 -4.4 -5.7499 -0.9967 3623684 BCB05_000160 CC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J12 compound treatment 9.0115729E7 -8950000.0 -0.46 1.02010292E8 -5720000.0 -0.31 -0.542 -0.9813 3623686 BCB05_000161 OCc1ccc(o1)C2=NO[C@@]34[C@H]2CCN4CCc5sccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J13 compound treatment 2.6313259E7 -7.27E7 -3.73 2.5981935E7 -8.17E7 -4.4 -5.7493 -0.9966 3623688 BCB05_000162 CC(=O)Oc1ccccc1C(=O)N2CCN(CC2)/[N+](=N/Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J14 compound treatment 8.5147468E7 -1.39E7 -0.71 9.6399593E7 -1.13E7 -0.61 -0.9357 -0.997 3623690 BCB05_000163 OCc1ccc(o1)C2=NO[C@@]34[C@H]2CCCN4CCc5c3[nH]c6ccccc56 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J15 compound treatment 2.6256623E7 -7.28E7 -3.73 2.6185546E7 -8.15E7 -4.39 -5.7436 -0.9967 3623692 BCB05_000164 CCN(CC)/[N+](=N/Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J16 compound treatment 9.202395E7 -7040000.0 -0.36 1.04035515E8 -3700000.0 -0.2 -0.3957 -0.9607 3623694 BCB05_000165 COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@]4(CC(=NO4)c5ccc(CO)o5)N1Cc6ccccc6.COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@]4(CC(=NO4)c5ccc(CO)o5)N1Cc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J17 compound treatment 2.6324778E7 -7.27E7 -3.73 2.6218632E7 -8.15E7 -4.39 -5.7399 -0.9967 3623696 BCB05_000166 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCCC2)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J18 compound treatment 9.6222248E7 -2840000.0 -0.15 1.06161619E8 -1570000.0 -0.08 -0.1626 -0.9666 3623698 BCB05_000167 COc1cc2CCN3CCC[C@H]4C(=NO[C@]43c2cc1OC)c5ccccc5OCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J19 compound treatment 2.647643E7 -7.26E7 -3.72 2.644691E7 -8.13E7 -4.38 -5.7257 -0.9967 3623700 BCB05_000168 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCCCC2)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J20 compound treatment 9.6882859E7 -2180000.0 -0.11 1.05290363E8 -2440000.0 -0.13 -0.1719 -0.9967 3623702 BCB05_000169 OCCOc1ccccc1C2=NO[C@@]34[C@H]2CCN4CCc5cc6OCOc6cc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J21 mock treatment 9.9364893E7 304000.0 0.02 1.05135172E8 -2600000.0 -0.14 -0.0878 -0.6244 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J22 mock treatment 9.9512859E7 452000.0 0.02 1.02769403E8 -4960000.0 -0.27 -0.1725 -0.6434 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J23 compound treatment 2.6730027E7 -7.23E7 -3.71 2.6427403E7 -8.13E7 -4.38 -5.7172 -0.9966 3623704 BCB05_000170 CN(C)/[N+](=N/Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 J24 compound treatment 1.16056414E8 1.7E7 0.87 1.14452352E8 6720000.0 0.36 0.8719 0.9243 3623706 BCB05_000171 OCCOc1ccccc1C2=NO[C@@]34[C@H]2CCN4CCc5sccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K01 compound treatment 1.17909867E8 1.88E7 0.97 1.08576736E8 846000.0 0.05 0.7153 0.7396 3623708 BCB05_000172 CCCCCCc1nc(cc2[C@@H](CC)O[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K02 compound treatment 1.08058671E8 9000000.0 0.46 1.13150435E8 5420000.0 0.29 0.5325 0.9756 3623710 BCB05_000173 CO/N=[N+](\[O-])/N(C)C1CCCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K03 compound treatment 1.07943454E8 8880000.0 0.46 1.04859946E8 -2870000.0 -0.15 0.2126 0.4422 3623712 BCB05_000174 CC[C@@H]1Cc2c(CC)c(nc(c3ccccc3)c2[Si](O1)(C(C)C)C(C)C)c4ccc(OC)nc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K04 compound treatment 1.04365555E8 5300000.0 0.27 1.1186611E8 4140000.0 0.22 0.3497 0.9951 3623714 BCB05_000175 CO/N=[N+](\[O-])/N(CC=C)C(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K05 compound treatment 4.3104953E7 -5.6E7 -2.87 2.9213132E7 -7.85E7 -4.23 -5.0177 -0.9821 3623716 BCB05_000176 CC(C)(C)OC(=O)N(CC#C)[C@H](/C=C/C1CC1)[C@@H](O)Cc2ccccc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K06 compound treatment 9.5384397E7 -3680000.0 -0.19 1.00500515E8 -7230000.0 -0.39 -0.4086 -0.9445 3623718 BCB05_000177 CC(C)N/[N+](=N/OCC=C)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K07 mock treatment 9.5227932E7 -3830000.0 -0.2 1.0522633E8 -2500000.0 -0.13 -0.2343 -0.9832 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K08 mock treatment 9.2416882E7 -6640000.0 -0.34 9.9564087E7 -8170000.0 -0.44 -0.5518 -0.992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K09 compound treatment 7.4404842E7 -2.47E7 -1.26 8.2152364E7 -2.56E7 -1.38 -1.8675 -0.9991 3623720 BCB05_000178 O[C@@H](Cc1ccccc1)[C@H]2[C@@H]3C=CCCC=C3CN2C(=O)c4ccccc4Br 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K10 compound treatment 8.8433796E7 -1.06E7 -0.54 9.9553945E7 -8180000.0 -0.44 -0.6965 -0.9944 3623722 BCB05_000179 CCN(CC)/[N+](=N/OCC(=O)O)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K11 compound treatment 5.2524237E7 -4.65E7 -2.39 5.5830752E7 -5.19E7 -2.79 -3.6628 -0.9969 3623724 BCB05_000180 CC(C)(C)OC(=O)N1CC2=CCCC=C[C@H]2[C@@H]1[C@@H](O)Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K12 compound treatment 8.8342105E7 -1.07E7 -0.55 9.8757003E7 -8970000.0 -0.48 -0.7302 -0.998 3623726 BCB05_000181 CCOC(=O)CO/N=[N+](\[O-])/N(CC)CC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K13 compound treatment 6.7816552E7 -3.12E7 -1.6 7.9030251E7 -2.87E7 -1.55 -2.2252 -0.9998 3623728 BCB05_000182 O[C@@H](Cc1ccccc1)[C@H]2[C@@H]3C=CCCC=C3CN2C(=O)Nc4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K14 compound treatment 8.7270905E7 -1.18E7 -0.6 1.004316E8 -7300000.0 -0.39 -0.7052 -0.9783 3623730 BCB05_000183 CCOC(=O)N1CCN(CC1)/[N+](=N/OC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K15 mock treatment 9.1722485E7 -7340000.0 -0.38 1.03016003E8 -4710000.0 -0.25 -0.4455 -0.9817 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K16 mock treatment 8.8228153E7 -1.08E7 -0.56 9.7366997E7 -1.04E7 -0.56 -0.7872 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K17 compound treatment 9.7101233E7 -1960000.0 -0.1 1.07446911E8 -284000.0 -0.02 -0.0818 -0.8054 3623732 BCB05_000184 O[C@@H](Cc1ccccc1)[C@H]2[C@@H]3C=CCCC=C3CN2CC#C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K18 compound treatment 9.245979E7 -6600000.0 -0.34 1.04670635E8 -3060000.0 -0.16 -0.3558 -0.9453 3623734 BCB05_000185 CCCO/N=[N+](\[O-])/N(CC)CC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K19 compound treatment 8.7285989E7 -1.18E7 -0.6 9.4169691E7 -1.36E7 -0.73 -0.9431 -0.9955 3623735 BCB05_000186 CCOC(=O)/C=C/[C@@H](Cc1ccccc1)[C@H](Nc2ccc(OC)cc2)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K20 compound treatment 1.00427411E8 1370000.0 0.07 1.05755877E8 -1970000.0 -0.11 -0.0257 -0.2016 3623737 BCB05_000187 CCO/N=[N+](\[O-])/N(CC)CC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K21 compound treatment 9.1220357E7 -7840000.0 -0.4 9.5845968E7 -1.19E7 -0.64 -0.7367 -0.9749 3623738 BCB05_000188 CCOC(=O)/C=C/[C@@H](Cc1ccccc1)[C@H](N(CC#C)c2ccc(OC)cc2)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K22 compound treatment 9.6414992E7 -2650000.0 -0.14 1.00304209E8 -7430000.0 -0.4 -0.3787 -0.8967 3623740 BCB05_000189 CC(=O)SCCO/N=[N+](\[O-])/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K23 mock treatment 1.01516269E8 2460000.0 0.13 1.0345021E8 -4280000.0 -0.23 -0.074 -0.2818 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 K24 mock treatment 1.13803043E8 1.47E7 0.76 1.10312036E8 2580000.0 0.14 0.6326 0.8234 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L01 compound treatment 2.6819801E7 -7.22E7 -3.7 2.6647713E7 -8.11E7 -4.37 -5.7056 -0.9966 3623742 BCB05_000190 CN1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L02 compound treatment 1.00163071E8 1100000.0 0.06 1.02059903E8 -5670000.0 -0.31 -0.176 -0.5667 3623744 BCB05_000191 OCCOc1ccccc1C2=NO[C@@]34[C@H]2CCCN4CCc5c3[nH]c6ccccc56 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L03 compound treatment 5.2066199E7 -4.7E7 -2.41 4.7093957E7 -6.06E7 -3.27 -4.0121 -0.9888 3623746 BCB05_000192 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCN(CC2)C(=O)OCc3ccccc3)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L04 compound treatment 9.8660063E7 -401000.0 -0.02 1.01431906E8 -6300000.0 -0.34 -0.2544 -0.7486 3623748 BCB05_000193 COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@]4(CC(=NO4)c5ccccc5OCCO)N1Cc6ccccc6.COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@]4(CC(=NO4)c5ccccc5OCCO)N1Cc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L05 compound treatment 2.5945583E7 -7.31E7 -3.75 2.5793763E7 -8.19E7 -4.41 -5.7698 -0.9967 3623750 BCB05_000194 CCCCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L06 compound treatment 9.1154646E7 -7910000.0 -0.41 9.7714761E7 -1.0E7 -0.54 -0.6679 -0.9901 3623752 BCB05_000195 COc1cc2CCN3CCC[C@H]4C(=NO[C@]43c2cc1OC)c5cc(OC)c6oc(CO)cc6c5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L07 mock treatment 9.4328187E7 -4730000.0 -0.24 9.8580189E7 -9150000.0 -0.49 -0.52 -0.9467 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L08 mock treatment 8.5497838E7 -1.36E7 -0.7 9.1618558E7 -1.61E7 -0.87 -1.1051 -0.994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L09 compound treatment 2.6060735E7 -7.3E7 -3.74 2.5778656E7 -8.2E7 -4.41 -5.7662 -0.9966 3623754 BCB05_000196 CN(C)S(=O)(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L10 compound treatment 5.2087347E7 -4.7E7 -2.41 5.9091163E7 -4.86E7 -2.62 -3.5545 -0.9991 3623756 BCB05_000197 COc1cc(cc2cc(CO)oc12)C3=NO[C@@]45[C@H]3CCN5CCc6cc7OCOc7cc64 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L11 compound treatment 2.6159828E7 -7.29E7 -3.74 2.5684579E7 -8.2E7 -4.42 -5.7662 -0.9965 3623758 BCB05_000198 CC(=O)Nc1ccc(OC(=O)N2CCN(CC2)/[N+](=N/Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/[O-])cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L12 compound treatment 8.5254525E7 -1.38E7 -0.71 9.5248103E7 -1.25E7 -0.67 -0.9757 -0.9997 3623760 BCB05_000199 COc1cc(cc2cc(CO)oc12)C3=NO[C@@]45[C@H]3CCN5CCc6sccc64 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L13 compound treatment 2.6519544E7 -7.25E7 -3.72 2.5881983E7 -8.18E7 -4.41 -5.7456 -0.9964 3623762 BCB05_000200 COCCOCCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L14 compound treatment 8.1910587E7 -1.72E7 -0.88 8.9903687E7 -1.78E7 -0.96 -1.3004 -0.999 3623764 BCB05_000201 COc1cc(cc2cc(CO)oc12)C3=NO[C@@]45[C@H]3CCCN5CCc6c4[nH]c7ccccc67 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L15 mock treatment 8.7951938E7 -1.11E7 -0.57 9.8636661E7 -9090000.0 -0.49 -0.7489 -0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L16 mock treatment 8.8112076E7 -1.09E7 -0.56 9.8100552E7 -9630000.0 -0.52 -0.7635 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L17 compound treatment 2.6433871E7 -7.26E7 -3.72 2.6095217E7 -8.16E7 -4.4 -5.7406 -0.9966 3623766 BCB05_000202 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCN(CC2)C(=O)OCC(Cl)(Cl)Cl)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L18 compound treatment 7.9486724E7 -1.96E7 -1.0 8.0041343E7 -2.77E7 -1.49 -1.7638 -0.9814 3623768 BCB05_000203 COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@]4(CC(=NO4)c5cc(OC)c6oc(CO)cc6c5)N1Cc7ccccc7.COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@]4(CC(=NO4)c5cc(OC)c6oc(CO)cc6c5)N1Cc7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L19 compound treatment 2.6158689E7 -7.29E7 -3.74 2.5978399E7 -8.18E7 -4.4 -5.755 -0.9967 3623770 BCB05_000204 COCCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L20 compound treatment 1.00017488E8 957000.0 0.05 1.02340402E8 -5390000.0 -0.29 -0.1706 -0.5795 3623772 BCB05_000205 COc1ccc(C2=NO[C@@]34[C@H]2CCCN4CCc5cc(OC)c(OC)cc53)c(Br)c1OCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L21 compound treatment 2.6121577E7 -7.29E7 -3.74 2.6146625E7 -8.16E7 -4.39 -5.75 -0.9968 3623774 BCB05_000206 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN(CC2)/[N+](=N/Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L22 compound treatment 9.5493455E7 -3570000.0 -0.18 1.02175917E8 -5550000.0 -0.3 -0.3408 -0.9721 3623776 BCB05_000207 COc1ccc(C2=NO[C@@]34[C@H]2CCN4CCc5cc6OCOc6cc53)c(Br)c1OCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L23 mock treatment 1.00526706E8 1470000.0 0.08 1.04781724E8 -2950000.0 -0.16 -0.0592 -0.3368 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 L24 mock treatment 1.07583852E8 8520000.0 0.44 1.09775074E8 2040000.0 0.11 0.3867 0.8585 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M01 compound treatment 1.26544974E8 2.75E7 1.41 1.3098187E8 2.33E7 1.25 1.8814 0.9983 3623778 BCB05_000208 CCOC(=O)c1nc2ccc(OC)cc2cc1Cc3ccccc3 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M02 compound treatment 1.00214325E8 1150000.0 0.06 1.03452163E8 -4280000.0 -0.23 -0.1211 -0.5092 3623779 BCB05_000209 CCN(CC)/[N+](=N/OCCSC(=O)C)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M03 compound treatment 9.1528513E7 -7530000.0 -0.39 9.5232097E7 -1.25E7 -0.67 -0.7489 -0.9652 3623781 BCB05_000210 CCOC(=O)/C=C/[C@@H](Cc1ccccc1)[C@H](N(C(=O)c2ccco2)c3ccc(OC)cc3)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M04 compound treatment 1.01347557E8 2290000.0 0.12 1.10163367E8 2430000.0 0.13 0.1755 0.9985 3623783 BCB05_000211 CO/N=[N+](\[O-])/N(C)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M05 compound treatment 9.4460086E7 -4600000.0 -0.24 9.7496217E7 -1.02E7 -0.55 -0.5565 -0.9282 3623785 BCB05_000212 CCOC(=O)[C@@H]1[C@H]2O[C@]3(C=C2)[C@H]1[C@@H](Cc4ccccc4)[C@H](N(C3=O)c5ccc(OC)cc5)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M06 compound treatment 9.5003544E7 -4060000.0 -0.21 1.02385433E8 -5350000.0 -0.29 -0.3506 -0.9873 3623787 BCB05_000213 CCN(CC)/[N+](=N/OCC(=O)N(C)C)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M07 compound treatment 8.6218065E7 -1.28E7 -0.66 9.4490567E7 -1.32E7 -0.71 -0.9696 -0.9992 3623789 BCB05_000214 CCCCC[C@H](/C=C/C(=O)OCC)[C@H](Nc1ccc(OC)cc1)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M08 compound treatment 9.6571521E7 -2490000.0 -0.13 1.07342753E8 -388000.0 -0.02 -0.105 -0.8121 3623791 BCB05_000215 CCN(CC)/[N+](=N/OCOC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M09 mock treatment 8.8491385E7 -1.06E7 -0.54 1.01717725E8 -6010000.0 -0.32 -0.612 -0.9697 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M10 mock treatment 8.5307401E7 -1.38E7 -0.7 1.0013133E8 -7600000.0 -0.41 -0.7878 -0.9665 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M11 compound treatment 5.3496541E7 -4.56E7 -2.34 6.2091069E7 -4.56E7 -2.46 -3.3892 -0.9997 3623792 BCB05_000216 CCCCC[C@H](/C=C/C(=O)OCC)[C@H](N(C(=O)c1ccco1)c2ccc(OC)cc2)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M12 compound treatment 8.5552089E7 -1.35E7 -0.69 9.8335323E7 -9400000.0 -0.51 -0.8473 -0.9881 3623794 BCB05_000217 COCO/N=[N+](\[O-])/N1CCCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M13 mock treatment 8.549082E7 -1.36E7 -0.7 9.7106054E7 -1.06E7 -0.57 -0.8964 -0.9953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M14 mock treatment 8.6497984E7 -1.26E7 -0.64 9.6756006E7 -1.1E7 -0.59 -0.8732 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M15 compound treatment 8.0189376E7 -1.89E7 -0.97 8.884515E7 -1.89E7 -1.02 -1.4031 -0.9997 3623796 BCB05_000218 CCOC(=O)/C=C/[C@@H](Cc1ccccc1[N+](=O)[O-])[C@H](Nc2ccc(OC)cc2)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M16 compound treatment 8.7323444E7 -1.17E7 -0.6 9.6213428E7 -1.15E7 -0.62 -0.8639 -0.9999 3623798 BCB05_000219 CO/N=[N+](\[O-])/N1CCN(CC1)C(=O)C(CCSC)NC(=O)C 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M17 compound treatment 7.6589276E7 -2.25E7 -1.15 7.7962455E7 -2.98E7 -1.6 -1.9479 -0.9868 3623800 BCB05_000220 CCCCC[C@@H]1[C@H]2[C@@H]([C@H]3O[C@@]2(C=C3)C(=O)N([C@@H]1C(=O)OCC)c4ccc(OC)cc4)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M18 compound treatment 9.1250833E7 -7810000.0 -0.4 1.04531249E8 -3200000.0 -0.17 -0.4049 -0.9291 3623802 BCB05_000221 CCOC(=O)N1CCN(CC1)/[N+](=N/OCOC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M19 compound treatment 8.1442209E7 -1.76E7 -0.9 8.2340013E7 -2.54E7 -1.37 -1.6054 -0.9797 3623804 BCB05_000222 CCOC(=O)/C=C/[C@@H](Cc1ccccc1[N+](=O)[O-])[C@H](N(C(=O)c2ccco2)c3ccc(OC)cc3)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M20 compound treatment 9.0534628E7 -8530000.0 -0.44 9.8837388E7 -8890000.0 -0.48 -0.6476 -0.999 3623806 BCB05_000223 CO/N=[N+](\[O-])/N1CCNCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M21 compound treatment 1.01915144E8 2850000.0 0.15 1.08581402E8 851000.0 0.05 0.1358 0.8861 3623808 BCB05_000224 CCOC(=O)[C@@H]1[C@H]2O[C@]3(C=C2)[C@H]1[C@@H](Cc4ccccc4[N+](=O)[O-])[C@H](N(C3=O)c5ccc(OC)cc5)C(=O)OCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M22 compound treatment 9.4169521E7 -4890000.0 -0.25 9.7828613E7 -9900000.0 -0.53 -0.5543 -0.9408 3623810 BCB05_000225 COCO/N=[N+](\[O-])/N1CCN(CCS)CC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M23 compound treatment 9.6530573E7 -2530000.0 -0.13 9.8291509E7 -9440000.0 -0.51 -0.4511 -0.86 3623812 BCB05_000226 COc1ccc(N[C@H]2[C@@H](Cc3ccccc3)COC2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 M24 compound treatment 1.08406184E8 9350000.0 0.48 1.05865262E8 -1870000.0 -0.1 0.2676 0.5469 3623814 BCB05_000227 COCO/N=[N+](\[O-])/N1CCN(CC1)C(=O)ON2C(=O)CCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N01 compound treatment 1.18264239E8 1.92E7 0.98 1.19362155E8 1.16E7 0.63 1.1389 0.9762 3623816 BCB05_000228 CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC=C4C[C@H](CC[C@]4(C)C3CC[C@]12C)OC(=O)N5CCN(CC5)/[N+](=N/Oc6ccc(cc6[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N02 compound treatment 1.04226747E8 5170000.0 0.26 1.07617109E8 -114000.0 -0.01 0.1829 0.6906 3623818 BCB05_000229 COc1ccc(C2=NO[C@@]34[C@H]2CCN4CCc5sccc53)c(Br)c1OCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N03 compound treatment 9.0232712E7 -8830000.0 -0.45 9.9584266E7 -8150000.0 -0.44 -0.6301 -0.9999 3623820 BCB05_000230 CCCCCCCCCCCCCCCCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N04 compound treatment 8.6642449E7 -1.24E7 -0.64 8.8838536E7 -1.89E7 -1.02 -1.1694 -0.9745 3623822 BCB05_000231 COc1ccc(C2=NO[C@@]34[C@H]2CCCN4CCc5c3[nH]c6ccccc56)c(Br)c1OCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N05 compound treatment 2.7064772E7 -7.2E7 -3.69 2.6392733E7 -8.13E7 -4.38 -5.7064 -0.9964 3623824 BCB05_000232 CCCCCCCCCCCCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N06 compound treatment 7.327529E7 -2.58E7 -1.32 7.7181574E7 -3.05E7 -1.65 -2.0978 -0.9941 3623826 BCB05_000233 COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@]4(CC(=NO4)c5ccc(OC)c(OCCO)c5Br)N1Cc6ccccc6.COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@]4(CC(=NO4)c5ccc(OC)c(OCCO)c5Br)N1Cc6ccccc6 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N07 compound treatment 2.6630338E7 -7.24E7 -3.71 2.5957071E7 -8.18E7 -4.4 -5.7388 -0.9964 3623828 BCB05_000234 CCOC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N08 compound treatment 3.6144879E7 -6.29E7 -3.22 3.5562516E7 -7.22E7 -3.89 -5.0282 -0.9957 3623830 BCB05_000235 Oc1cccc2ccc(nc12)C3=NO[C@@]45[C@H]3CCN5CCc6sccc64 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N09 mock treatment 8.591895E7 -1.31E7 -0.67 1.03485463E8 -4250000.0 -0.23 -0.6379 -0.8969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N10 mock treatment 7.8813149E7 -2.02E7 -1.04 9.65757E7 -1.12E7 -0.6 -1.1586 -0.9662 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N11 compound treatment 2.6771063E7 -7.23E7 -3.71 2.6053871E7 -8.17E7 -4.4 -5.73 -0.9964 3623832 BCB05_000236 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCN(CC2)c3ccccc3)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N12 compound treatment 3.2897137E7 -6.62E7 -3.39 3.3986599E7 -7.37E7 -3.97 -5.2059 -0.9969 3623834 BCB05_000237 Oc1cccc2ccc(nc12)C3=NO[C@@]45[C@H]3CCCN5CCc6c4[nH]c7ccccc67 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N13 mock treatment 8.6104837E7 -1.3E7 -0.66 1.00009801E8 -7720000.0 -0.42 -0.7635 -0.9746 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N14 mock treatment 8.4205904E7 -1.49E7 -0.76 1.02045049E8 -5690000.0 -0.31 -0.7549 -0.9199 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N15 compound treatment 2.663726E7 -7.24E7 -3.71 2.6097774E7 -8.16E7 -4.4 -5.7332 -0.9965 3623836 BCB05_000238 NC(=O)C1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N16 compound treatment 4.3865492E7 -5.52E7 -2.83 3.9230691E7 -6.85E7 -3.69 -4.6087 -0.9914 3623838 BCB05_000239 COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@]4(CC(=NO4)c5ccc6cccc(O)c6n5)N1Cc7ccccc7.COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@@]4(CC(=NO4)c5ccc6cccc(O)c6n5)N1Cc7ccccc7 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N17 compound treatment 2.6808095E7 -7.23E7 -3.7 2.6503213E7 -8.12E7 -4.37 -5.7115 -0.9966 3623840 BCB05_000240 [O-][N+](=O)c1ccc(O/N=[N+](\[O-])/N2CCN(CC2)c3ncccn3)c(c1)[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N18 compound treatment 8.7784065E7 -1.13E7 -0.58 1.02882196E8 -4850000.0 -0.26 -0.5933 -0.9355 3623842 BCB05_000241 CCOc1cc(ccc1OCCO)C2=NO[C@@]34[C@H]2CCCN4CCc5cc(OC)c(OC)cc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N19 compound treatment 2.6437083E7 -7.26E7 -3.72 2.6251291E7 -8.15E7 -4.39 -5.7346 -0.9966 3623844 BCB05_000242 COCCOCC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N20 compound treatment 1.01671496E8 2610000.0 0.13 1.07495363E8 -235000.0 -0.01 0.0856 0.6373 3623846 BCB05_000243 CCOc1cc(ccc1OCCO)C2=NO[C@@]34[C@H]2CCN4CCc5cc6OCOc6cc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N21 compound treatment 6.6934551E7 -3.21E7 -1.65 5.9893396E7 -4.78E7 -2.58 -2.9859 -0.9766 3623848 BCB05_000244 COc1ccc2cc(ccc2c1)[C@H](C)C(=O)N3CCN(CC3)/[N+](=N/Oc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N22 compound treatment 9.5585984E7 -3470000.0 -0.18 1.0248665E8 -5240000.0 -0.28 -0.3256 -0.9753 3623850 BCB05_000245 CCOc1cc(ccc1OCCO)C2=NO[C@@]34[C@H]2CCN4CCc5sccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N23 compound treatment 7.377226E7 -2.53E7 -1.3 7.5323601E7 -3.24E7 -1.75 -2.1505 -0.9893 3623852 BCB05_000246 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N4CCN(CC4)/[N+](=N/Oc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])/[O-])c2c1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 N24 compound treatment 1.0370996E8 4650000.0 0.24 1.02549111E8 -5180000.0 -0.28 -0.0288 -0.0786 3623854 BCB05_000247 CCOc1cc(ccc1OCCO)C2=NO[C@@]34[C@H]2CCCN4CCc5c3[nH]c6ccccc56 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O01 compound treatment 1.12217942E8 1.32E7 0.67 1.11224581E8 3490000.0 0.19 0.6099 0.8711 3623856 BCB05_000248 COc1ccc(N[C@H]2[C@H](Cc3ccccc3)COC2=O)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O02 compound treatment 1.07744802E8 8680000.0 0.45 1.09805742E8 2070000.0 0.11 0.3937 0.858 3623857 BCB05_000249 CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)N1CCN(CC1)/[N+](=N/OCOC)/[O-])OC(=O)CCCCCCCCCCCCCCC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O03 compound treatment 7.5775029E7 -2.33E7 -1.19 6.3471082E7 -4.43E7 -2.38 -2.5292 -0.9489 3623859 BCB05_000250 CC(CN1CCCC1)C(=O)c2ccc(F)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O04 compound treatment 8.9581227E7 -9480000.0 -0.49 9.9962167E7 -7770000.0 -0.42 -0.6394 -0.9972 3623860 BCB05_000251 CO/N=[N+](\[O-])/N1CCN(CC1)c2ncnc3n(cnc23)[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O05 compound treatment 4.9730656E7 -4.93E7 -2.53 2.6211878E7 -8.15E7 -4.39 -4.8919 -0.9657 3623862 BCB05_000252 CC(CN1CCOCC1)C(=O)c2ccc(cc2)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O06 compound treatment 8.6437061E7 -1.26E7 -0.65 1.06966513E8 -764000.0 -0.04 -0.4866 -0.7506 3623863 BCB05_000253 COCCOCCOCCOCCOCCOCCOCCOC(=O)N1CCN(CC1)/[N+](=N/OCOC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O07 compound treatment 2.6507363E7 -7.26E7 -3.72 2.6423107E7 -8.13E7 -4.38 -5.7255 -0.9967 3623865 BCB05_000254 CC(CN1CCCCC1)C(=O)c2ccc(F)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O08 compound treatment 7.4287426E7 -2.48E7 -1.27 8.3172992E7 -2.46E7 -1.32 -1.8329 -0.9998 3623866 BCB05_000255 CO/N=[N+](\[O-])/N1CCN(CC1)C(=O)ON2C(=O)CCC2=O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O09 compound treatment 2.6740801E7 -7.23E7 -3.71 2.6362769E7 -8.14E7 -4.38 -5.7193 -0.9965 3623868 BCB05_000256 CCN(CC)CC(C)C(=O)c1ccc(cc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O10 compound treatment 8.3323816E7 -1.57E7 -0.81 9.0752452E7 -1.7E7 -0.91 -1.2168 -0.998 3623869 BCB05_000257 CO/N=[N+](\[O-])/N1CCN(CC1)C(=O)C(C)c2ccc(CC(C)C)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O11 mock treatment 8.1349207E7 -1.77E7 -0.91 9.7972447E7 -9760000.0 -0.53 -1.0135 -0.9662 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O12 mock treatment 8.3223444E7 -1.58E7 -0.81 9.9421795E7 -8310000.0 -0.45 -0.8904 -0.9606 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O13 compound treatment 4.7711688E7 -5.13E7 -2.63 4.6604538E7 -6.11E7 -3.29 -4.1885 -0.9939 3623871 BCB05_000258 CCNCC(C)C(=O)c1ccc(cc1)C(F)(F)F 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O14 compound treatment 8.7597078E7 -1.15E7 -0.59 1.04910573E8 -2820000.0 -0.15 -0.5228 -0.8616 3623730 BCB05_000259 CCOC(=O)N1CCN(CC1)/[N+](=N/OC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O15 compound treatment 7.3492945E7 -2.56E7 -1.31 9.4483098E7 -1.32E7 -0.71 -1.4311 -0.9591 3076306 BCB05_000260 CC(=O)c1ccc(cc1O)N2CCOCC2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O16 compound treatment 7.4339725E7 -2.47E7 -1.27 1.06831668E8 -899000.0 -0.05 -0.9302 -0.7336 3623872 BCB05_000261 COCCOCCOCCOCCOCCOCCOCCOC(=O)N1CCN(CC1)/[N+](=N/OC)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O17 compound treatment 5.8468486E7 -4.06E7 -2.08 6.5915305E7 -4.18E7 -2.25 -3.0634 -0.9992 3623874 BCB05_000262 O=c1cc(oc(c1)c2cccc3Sc4ccccc4Sc23)N5CCOCC5 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O18 compound treatment 9.8822318E7 -239000.0 -0.01 1.07560399E8 -170000.0 -0.01 -0.0151 -0.99 3623875 BCB05_000263 CCOC(=O)N1CCN(CC1)/[N+](=N/OC=C)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O19 compound treatment 9.9523867E7 463000.0 0.02 1.01544544E8 -6190000.0 -0.33 -0.2188 -0.6551 3623877 BCB05_000264 C[Si](C)(CN1CCCC1)Cc2ccc(F)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O20 compound treatment 9.7271082E7 -1790000.0 -0.09 1.00961231E8 -6770000.0 -0.36 -0.3226 -0.8583 3623878 BCB05_000265 CCOC(=O)N1CCN(CC1)/[N+](=N/OCCBr)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O21 compound treatment 1.18354657E8 1.93E7 0.99 1.17655376E8 9920000.0 0.53 1.0771 0.9583 3623880 BCB05_000266 C[Si](C)(CN1CCOCC1)Cc2ccc(F)cc2 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O22 compound treatment 1.09144532E8 1.01E7 0.52 1.02784149E8 -4950000.0 -0.27 0.1771 0.3046 3623881 BCB05_000267 COCO/N=[N+](\[O-])/N1CCNCC1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O23 compound treatment 1.09611817E8 1.06E7 0.54 1.09805495E8 2070000.0 0.11 0.4614 0.8356 3623883 BCB05_000268 CCN(CC)C[Si](C)(C)Cc1ccc(F)cc1 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 O24 compound treatment 1.17281127E8 1.82E7 0.93 1.16038585E8 8310000.0 0.45 0.9767 0.9432 BCB05_000269 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P01 compound treatment 2.7474224E7 -7.16E7 -3.67 2.7831174E7 -7.99E7 -4.3 -5.6368 -0.9969 3623884 BCB05_000270 CC(C(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-])c3cccc(c3)C(=O)c4ccccc4 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P02 compound treatment 9.6107872E7 -2950000.0 -0.15 9.6913013E7 -1.08E7 -0.58 -0.5189 -0.8622 3623886 BCB05_000271 CCOc1cc(ccc1OCCO)C2=NO[C@@]3(C2)N(Cc4ccccc4)[C@@H](Cc5c3[nH]c6ccccc56)C(=O)OC.CCOc1cc(ccc1OCCO)C2=NO[C@]3(C2)N(Cc4ccccc4)[C@@H](Cc5c3[nH]c6ccccc56)C(=O)OC 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P03 compound treatment 1.01351476E8 2290000.0 0.12 1.07202716E8 -528000.0 -0.03 0.0629 0.5208 3623888 BCB05_000272 COc1ccc2cc(ccc2c1)[C@H](C)C(=O)Oc3cc(O/N=[N+](\[O-])/N(C)C)c(cc3[N+](=O)[O-])[N+](=O)[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P04 compound treatment 9.7673814E7 -1390000.0 -0.07 9.7689829E7 -1.0E7 -0.54 -0.4326 -0.7932 3623890 BCB05_000273 OCc1ccc(o1)C2=NO[C@@]34[C@H]2CCN4Cc5sccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P05 compound treatment 2.6863072E7 -7.22E7 -3.7 2.6690455E7 -8.1E7 -4.36 -5.7024 -0.9966 3623892 BCB05_000274 COCC(=O)N1CCN(CC1)/[N+](=N/Oc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P06 compound treatment 1.00308014E8 1250000.0 0.06 1.02921677E8 -4810000.0 -0.26 -0.1379 -0.5171 3623894 BCB05_000275 OCCOc1ccccc1C2=NO[C@@]34[C@H]2CCN4Cc5sccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P07 compound treatment 2.6915674E7 -7.21E7 -3.7 2.6964817E7 -8.08E7 -4.35 -5.6901 -0.9967 3623896 BCB05_000276 CN(C)/[N+](=N/Oc1cc(N(C)C(=O)c2ccccc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P08 compound treatment 8.3428992E7 -1.56E7 -0.8 9.1640431E7 -1.61E7 -0.87 -1.1792 -0.9992 3623898 BCB05_000277 COc1cc(cc2cc(CO)oc12)C3=NO[C@@]45[C@H]3CCN5Cc6sccc64 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P09 compound treatment 4.5114199E7 -5.39E7 -2.76 5.5144221E7 -5.26E7 -2.83 -3.9575 -0.9999 3623900 BCB05_000278 CN(C)/[N+](=N/Oc1cc(Nc2ccc(CO)cc2)c(cc1[N+](=O)[O-])[N+](=O)[O-])/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P10 compound treatment 8.0193002E7 -1.89E7 -0.97 8.6898871E7 -2.08E7 -1.12 -1.477 -0.9973 3623902 BCB05_000279 COc1ccc(C2=NO[C@@]34[C@H]2CCN4Cc5sccc53)c(Br)c1OCCO 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P11 mock treatment 8.3674125E7 -1.54E7 -0.79 9.9750771E7 -7980000.0 -0.43 -0.8615 -0.9592 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P12 mock treatment 8.5725533E7 -1.33E7 -0.68 1.09212337E8 1480000.0 0.08 -0.4269 -0.6204 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P13 compound treatment 8.4937245E7 -1.41E7 -0.72 1.02801502E8 -4930000.0 -0.27 -0.6996 -0.9073 3623904 BCB05_000280 CCN(CC)/[N+](=N/O[C@@H]1OC(CO)[C@@H](O)[C@H](O)[C@H]1O)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P14 compound treatment 8.5651952E7 -1.34E7 -0.69 9.7847358E7 -9880000.0 -0.53 -0.8623 -0.992 3623905 BCB05_000281 CCOc1cc(ccc1OCCO)C2=NO[C@@]34[C@H]2CCN4Cc5sccc53 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P15 compound treatment 8.923418E7 -9830000.0 -0.5 1.04180063E8 -3550000.0 -0.19 -0.4913 -0.912 3623907 BCB05_000282 OCC1O[C@@H](O/N=[N+](\[O-])/N2CCCCC2)[C@H](O)[C@@H](O)[C@@H]1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P16 mock treatment 8.4029948E7 -1.5E7 -0.77 1.05540444E8 -2190000.0 -0.12 -0.6281 -0.806 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P17 compound treatment 9.2438519E7 -6620000.0 -0.34 1.06024017E8 -1710000.0 -0.09 -0.305 -0.8673 3623909 BCB05_000283 CCOC(=O)N1CCN(CC1)/[N+](=N/O[C@@H]2OC(CO)[C@@H](O)[C@H](O)[C@H]2O)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P18 mock treatment 9.0451561E7 -8610000.0 -0.44 1.06285996E8 -1440000.0 -0.08 -0.367 -0.8191 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P19 compound treatment 9.3969136E7 -5090000.0 -0.26 1.07542385E8 -188000.0 -0.01 -0.1917 -0.734 3623911 BCB05_000284 CC(C)N/[N+](=N/O[C@@H]1OC(CO)[C@@H](O)[C@H](O)[C@H]1O)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P20 mock treatment 9.7780795E7 -1280000.0 -0.07 1.09588999E8 1860000.0 0.1 0.0244 0.2036 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P21 compound treatment 9.7566164E7 -1490000.0 -0.08 1.07547664E8 -183000.0 -0.01 -0.0611 -0.7916 3623913 BCB05_000285 CC(C)N(C)/[N+](=N/O[C@@H]1OC(CO)[C@@H](O)[C@H](O)[C@H]1O)/[O-] 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P22 mock treatment 1.00743295E8 1680000.0 0.09 1.01519141E8 -6210000.0 -0.33 -0.1756 -0.5082 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P23 compound treatment 1.05060712E8 6000000.0 0.31 1.10165861E8 2440000.0 0.13 0.3102 0.9278 3623915 BCB05_000286 CC(C)/N=[N+](\[O-])/N(C)O[C@@H]1OC(CO)[C@@H](O)[C@H](O)[C@H]1O 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.2414 P24 mock treatment 1.09592597E8 1.05E7 0.54 1.18006156E8 1.03E7 0.55 0.7729 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A01 mock treatment 1.18396078E8 2.11E7 1.08 1.20057593E8 2.44E7 1.31 1.6945 0.9954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A02 mock treatment 1.14924266E8 1.76E7 0.9 1.06359791E8 1.07E7 0.58 1.0471 0.9763 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A03 mock treatment 1.06787644E8 9510000.0 0.49 1.00456385E8 4800000.0 0.26 0.5274 0.956 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A04 mock treatment 1.1176185E8 1.45E7 0.74 1.12222443E8 1.66E7 0.89 1.1557 0.9958 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A05 mock treatment 1.01105442E8 3830000.0 0.2 9.5959763E7 304000.0 0.02 0.1503 0.7635 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A06 mock treatment 9.5170121E7 -2110000.0 -0.11 9.1859747E7 -3800000.0 -0.2 -0.221 -0.9556 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A07 mock treatment 9.432486E7 -2950000.0 -0.15 8.8333723E7 -7320000.0 -0.39 -0.3859 -0.9136 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A08 mock treatment 9.376949E7 -3510000.0 -0.18 8.8925389E7 -6730000.0 -0.36 -0.3835 -0.9477 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A09 mock treatment 8.8030289E7 -9250000.0 -0.47 8.2888209E7 -1.28E7 -0.69 -0.8213 -0.9835 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A10 mock treatment 9.0639315E7 -6640000.0 -0.34 8.394518E7 -1.17E7 -0.63 -0.6865 -0.9581 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A11 mock treatment 9.5098782E7 -2180000.0 -0.11 8.503518E7 -1.06E7 -0.57 -0.4834 -0.8296 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A12 mock treatment 9.4491011E7 -2790000.0 -0.14 8.5581967E7 -1.01E7 -0.54 -0.4846 -0.8639 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A13 mock treatment 1.02003908E8 4730000.0 0.24 9.5004018E7 -652000.0 -0.04 0.1464 0.5984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A14 mock treatment 9.4843316E7 -2440000.0 -0.12 8.865111E7 -7000000.0 -0.38 -0.355 -0.8935 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A15 mock treatment 9.5288368E7 -1990000.0 -0.1 8.7666773E7 -7990000.0 -0.43 -0.3763 -0.8512 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A16 mock treatment 1.00025434E8 2750000.0 0.14 9.6545107E7 890000.0 0.05 0.1334 0.8972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A17 mock treatment 9.9829482E7 2550000.0 0.13 9.578659E7 131000.0 0.01 0.0974 0.7442 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A18 mock treatment 1.05323361E8 8040000.0 0.41 1.07602762E8 1.19E7 0.64 0.7465 0.9769 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A19 mock treatment 1.03912437E8 6630000.0 0.34 9.9139489E7 3480000.0 0.19 0.3731 0.9607 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A20 mock treatment 1.03345948E8 6070000.0 0.31 1.01331011E8 5680000.0 0.31 0.436 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A21 mock treatment 1.01572908E8 4290000.0 0.22 1.00177429E8 4520000.0 0.24 0.3278 0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A22 mock treatment 1.11210619E8 1.39E7 0.71 1.1664329E8 2.1E7 1.13 1.3041 0.9755 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A23 mock treatment 1.16175802E8 1.89E7 0.97 1.13407605E8 1.78E7 0.96 1.3608 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base A24 mock treatment 1.25760623E8 2.85E7 1.46 1.22925234E8 2.73E7 1.47 2.0706 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B01 mock treatment 1.15696273E8 1.84E7 0.94 1.19827548E8 2.42E7 1.3 1.5879 0.9875 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B02 mock treatment 1.02994583E8 5720000.0 0.29 9.6144661E7 489000.0 0.03 0.2258 0.7676 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B03 mock treatment 9.7237972E7 -40900.0 0.0 9.168227E7 -3970000.0 -0.21 -0.1528 -0.714 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B04 mock treatment 9.3491321E7 -3790000.0 -0.19 8.7860348E7 -7800000.0 -0.42 -0.4341 -0.9386 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B05 mock treatment 9.2051592E7 -5230000.0 -0.27 8.4449419E7 -1.12E7 -0.6 -0.6162 -0.9332 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B06 mock treatment 8.9041287E7 -8240000.0 -0.42 8.3813598E7 -1.18E7 -0.64 -0.7495 -0.9799 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B07 mock treatment 9.0734016E7 -6540000.0 -0.34 8.8099292E7 -7560000.0 -0.41 -0.5249 -0.9954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B08 mock treatment 8.6736801E7 -1.05E7 -0.54 8.2041526E7 -1.36E7 -0.73 -0.9005 -0.9887 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B09 mock treatment 8.7138598E7 -1.01E7 -0.52 8.2349021E7 -1.33E7 -0.72 -0.8742 -0.9876 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B10 mock treatment 7.8546282E7 -1.87E7 -0.96 6.9471639E7 -2.62E7 -1.41 -1.6759 -0.9825 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B11 mock treatment 7.9896314E7 -1.74E7 -0.89 7.0538574E7 -2.51E7 -1.35 -1.5864 -0.9795 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B12 mock treatment 8.5743057E7 -1.15E7 -0.59 7.6670119E7 -1.9E7 -1.02 -1.141 -0.9661 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B13 mock treatment 8.7926722E7 -9350000.0 -0.48 7.8846119E7 -1.68E7 -0.91 -0.979 -0.9558 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B14 mock treatment 8.8170449E7 -9110000.0 -0.47 7.9621419E7 -1.6E7 -0.86 -0.9407 -0.9583 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B15 mock treatment 8.8837433E7 -8440000.0 -0.43 8.2877812E7 -1.28E7 -0.69 -0.7925 -0.975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B16 mock treatment 9.4796043E7 -2480000.0 -0.13 8.428033E7 -1.14E7 -0.61 -0.5231 -0.8361 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B17 mock treatment 9.0164312E7 -7110000.0 -0.36 8.5429101E7 -1.02E7 -0.55 -0.6472 -0.98 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B18 mock treatment 9.2295414E7 -4980000.0 -0.26 8.9431602E7 -6220000.0 -0.34 -0.4176 -0.991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B19 mock treatment 9.7488262E7 209000.0 0.01 9.2162991E7 -3490000.0 -0.19 -0.1254 -0.6657 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B20 mock treatment 1.03250336E8 5970000.0 0.31 1.06731944E8 1.11E7 0.6 0.6382 0.9519 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B21 mock treatment 1.01147061E8 3870000.0 0.2 1.02072013E8 6420000.0 0.35 0.3845 0.9652 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B22 mock treatment 1.0312413E8 5850000.0 0.3 9.9245972E7 3590000.0 0.19 0.3486 0.9776 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B23 mock treatment 1.08734594E8 1.15E7 0.59 1.0864778E8 1.3E7 0.7 0.9099 0.9962 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base B24 mock treatment 1.20109221E8 2.28E7 1.17 1.19303046E8 2.36E7 1.27 1.7279 0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C01 mock treatment 1.1170123E8 1.44E7 0.74 1.05977856E8 1.03E7 0.56 0.9157 0.9901 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C02 mock treatment 9.9442046E7 2160000.0 0.11 9.2848372E7 -2810000.0 -0.15 -0.0285 -0.152 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C03 mock treatment 9.7063218E7 -216000.0 -0.01 9.1458546E7 -4200000.0 -0.23 -0.1676 -0.7408 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C04 mock treatment 9.7351244E7 72400.0 0.0 9.0695975E7 -4960000.0 -0.27 -0.1862 -0.6972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C05 mock treatment 9.3054563E7 -4220000.0 -0.22 8.5526273E7 -1.01E7 -0.55 -0.5388 -0.9181 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C06 mock treatment 8.7592449E7 -9690000.0 -0.5 8.2501217E7 -1.32E7 -0.71 -0.8519 -0.9849 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C07 mock treatment 9.1569715E7 -5710000.0 -0.29 8.129456E7 -1.44E7 -0.77 -0.7537 -0.9116 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C08 mock treatment 8.6836394E7 -1.04E7 -0.54 7.7300894E7 -1.84E7 -0.99 -1.0774 -0.9585 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C09 mock treatment 8.3033134E7 -1.42E7 -0.73 8.6542072E7 -9110000.0 -0.49 -0.8633 -0.9813 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C10 mock treatment 7.6995998E7 -2.03E7 -1.04 7.0167535E7 -2.55E7 -1.37 -1.7056 -0.9906 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C11 mock treatment 8.4613992E7 -1.27E7 -0.65 7.7022682E7 -1.86E7 -1.0 -1.1685 -0.9778 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C12 mock treatment 8.8130331E7 -9150000.0 -0.47 7.5049336E7 -2.06E7 -1.11 -1.1162 -0.9266 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C13 mock treatment 8.9747799E7 -7530000.0 -0.39 8.2158031E7 -1.35E7 -0.73 -0.7869 -0.9562 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C14 mock treatment 8.8515304E7 -8760000.0 -0.45 7.884905E7 -1.68E7 -0.91 -0.9576 -0.9477 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C15 mock treatment 8.8076047E7 -9200000.0 -0.47 8.1468398E7 -1.42E7 -0.76 -0.8737 -0.9731 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C16 mock treatment 8.6568939E7 -1.07E7 -0.55 8.1348745E7 -1.43E7 -0.77 -0.9329 -0.9862 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C17 mock treatment 9.4566594E7 -2710000.0 -0.14 9.4156207E7 -1500000.0 -0.08 -0.1554 -0.9666 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C18 mock treatment 9.1169115E7 -6110000.0 -0.31 8.6512066E7 -9140000.0 -0.49 -0.5696 -0.9761 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C19 mock treatment 9.424408E7 -3030000.0 -0.16 8.9346444E7 -6310000.0 -0.34 -0.3502 -0.9373 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C20 mock treatment 9.7066065E7 -213000.0 -0.01 9.2848971E7 -2810000.0 -0.15 -0.1146 -0.7562 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C21 mock treatment 1.01134169E8 3860000.0 0.2 1.01061405E8 5410000.0 0.29 0.3456 0.9822 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C22 mock treatment 1.03774687E8 6500000.0 0.33 1.02094596E8 6440000.0 0.35 0.4806 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C23 mock treatment 1.09842424E8 1.26E7 0.64 1.03628108E8 7970000.0 0.43 0.7589 0.9806 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base C24 mock treatment 1.17794705E8 2.05E7 1.05 1.21977134E8 2.63E7 1.42 1.7458 0.9892 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D01 mock treatment 1.07492821E8 1.02E7 0.52 1.03124828E8 7470000.0 0.4 0.6546 0.9915 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D02 mock treatment 9.8816291E7 1540000.0 0.08 9.2461572E7 -3190000.0 -0.17 -0.0659 -0.3483 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D03 mock treatment 9.4836053E7 -2440000.0 -0.13 9.7520912E7 1870000.0 0.1 -0.0175 -0.109 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D04 mock treatment 9.2727543E7 -4550000.0 -0.23 8.617454E7 -9480000.0 -0.51 -0.526 -0.937 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D05 mock treatment 9.4625331E7 -2650000.0 -0.14 8.8650662E7 -7000000.0 -0.38 -0.3629 -0.905 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D06 mock treatment 9.1845574E7 -5430000.0 -0.28 8.5981498E7 -9670000.0 -0.52 -0.5653 -0.9569 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D07 mock treatment 8.5734925E7 -1.15E7 -0.59 8.1757081E7 -1.39E7 -0.75 -0.9476 -0.9932 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D08 mock treatment 8.0763997E7 -1.65E7 -0.85 7.9512129E7 -1.61E7 -0.87 -1.2132 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D09 mock treatment 7.4949394E7 -2.23E7 -1.14 7.4630802E7 -2.1E7 -1.13 -1.6098 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D10 mock treatment 7.7006621E7 -2.03E7 -1.04 7.1262615E7 -2.44E7 -1.31 -1.6635 -0.9933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D11 mock treatment 8.1600031E7 -1.57E7 -0.8 7.669525E7 -1.9E7 -1.02 -1.2902 -0.993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D12 mock treatment 8.4212454E7 -1.31E7 -0.67 8.5284452E7 -1.04E7 -0.56 -0.8685 -0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D13 mock treatment 8.9873377E7 -7410000.0 -0.38 7.9622305E7 -1.6E7 -0.86 -0.8789 -0.9319 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D14 mock treatment 9.0551282E7 -6730000.0 -0.34 8.0729698E7 -1.49E7 -0.8 -0.8122 -0.9286 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D15 mock treatment 9.0734153E7 -6540000.0 -0.34 8.7541573E7 -8110000.0 -0.44 -0.5462 -0.9915 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D16 mock treatment 9.3919537E7 -3360000.0 -0.17 9.5294564E7 -361000.0 -0.02 -0.1355 -0.782 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D17 mock treatment 9.0970069E7 -6310000.0 -0.32 8.7602726E7 -8050000.0 -0.43 -0.5353 -0.9895 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D18 mock treatment 9.7218013E7 -60800.0 0.0 9.0899541E7 -4760000.0 -0.26 -0.1833 -0.7157 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D19 mock treatment 1.01366885E8 4090000.0 0.21 9.2309046E7 -3350000.0 -0.18 0.0207 0.075 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D20 mock treatment 9.95454E7 2270000.0 0.12 9.4784086E7 -872000.0 -0.05 0.049 0.3908 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D21 mock treatment 9.7403895E7 125000.0 0.01 9.9214244E7 3560000.0 0.19 0.14 0.7303 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D22 mock treatment 1.03588037E8 6310000.0 0.32 1.05666208E8 1.0E7 0.54 0.6098 0.9701 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D23 mock treatment 1.03474857E8 6200000.0 0.32 1.07544283E8 1.19E7 0.64 0.6773 0.9477 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base D24 mock treatment 1.13741469E8 1.65E7 0.84 1.20223499E8 2.46E7 1.32 1.5321 0.9764 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E01 mock treatment 1.06134925E8 8860000.0 0.45 1.01766877E8 6110000.0 0.33 0.5537 0.9875 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E02 mock treatment 1.00033068E8 2750000.0 0.14 9.1863771E7 -3790000.0 -0.2 -0.0446 -0.1795 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E03 mock treatment 1.01020833E8 3740000.0 0.19 1.0594777E8 1.03E7 0.55 0.5275 0.8995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E04 mock treatment 9.9616063E7 2340000.0 0.12 9.6597278E7 942000.0 0.05 0.1206 0.9268 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E05 mock treatment 9.6380392E7 -898000.0 -0.05 9.0756242E7 -4900000.0 -0.26 -0.2191 -0.8182 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E06 mock treatment 9.0946443E7 -6330000.0 -0.32 9.5192727E7 -463000.0 -0.02 -0.2471 -0.7592 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E07 mock treatment 8.8233446E7 -9050000.0 -0.46 8.4543726E7 -1.11E7 -0.6 -0.7509 -0.992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E08 mock treatment 8.6279714E7 -1.1E7 -0.56 8.517297E7 -1.05E7 -0.56 -0.7978 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E09 mock treatment 7.9708208E7 -1.76E7 -0.9 8.1411626E7 -1.42E7 -0.77 -1.1792 -0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E10 mock treatment 7.4341554E7 -2.29E7 -1.18 7.5415672E7 -2.02E7 -1.09 -1.602 -0.9993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E11 mock treatment 7.8978899E7 -1.83E7 -0.94 7.6180283E7 -1.95E7 -1.05 -1.4048 -0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E12 mock treatment 8.3204051E7 -1.41E7 -0.72 8.614626E7 -9510000.0 -0.51 -0.8722 -0.9859 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E13 mock treatment 8.8084003E7 -9190000.0 -0.47 8.2200338E7 -1.35E7 -0.72 -0.8456 -0.9783 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E14 mock treatment 9.0697915E7 -6580000.0 -0.34 8.7769812E7 -7890000.0 -0.42 -0.5388 -0.9935 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E15 mock treatment 9.1275794E7 -6000000.0 -0.31 9.0415909E7 -5240000.0 -0.28 -0.4171 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E16 mock treatment 9.2026669E7 -5250000.0 -0.27 9.1398575E7 -4260000.0 -0.23 -0.3524 -0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E17 mock treatment 9.4389116E7 -2890000.0 -0.15 9.4264562E7 -1390000.0 -0.07 -0.1577 -0.9501 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E18 mock treatment 9.9380399E7 2100000.0 0.11 9.721946E7 1560000.0 0.08 0.1357 0.9926 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E19 mock treatment 1.00065722E8 2790000.0 0.14 9.8964316E7 3310000.0 0.18 0.227 0.994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E20 mock treatment 1.04225109E8 6950000.0 0.36 1.04363374E8 8710000.0 0.47 0.5833 0.9908 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E21 mock treatment 9.9920298E7 2640000.0 0.14 9.9929372E7 4270000.0 0.23 0.2585 0.968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E22 mock treatment 1.1008753E8 1.28E7 0.66 1.097746E8 1.41E7 0.76 1.0018 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E23 mock treatment 1.08046152E8 1.08E7 0.55 1.08927781E8 1.33E7 0.71 0.8956 0.9918 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base E24 mock treatment 1.14852648E8 1.76E7 0.9 1.120012E8 1.63E7 0.88 1.2593 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F01 mock treatment 1.08141145E8 1.09E7 0.56 1.09853412E8 1.42E7 0.76 0.9343 0.9879 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F02 mock treatment 1.06001423E8 8720000.0 0.45 1.08838689E8 1.32E7 0.71 0.8181 0.9751 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F03 mock treatment 9.8742899E7 1460000.0 0.08 9.5000108E7 -655000.0 -0.04 0.0281 0.3389 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F04 mock treatment 9.8126474E7 848000.0 0.04 9.4011448E7 -1640000.0 -0.09 -0.0319 -0.3233 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F05 mock treatment 9.2518189E7 -4760000.0 -0.24 8.9907601E7 -5750000.0 -0.31 -0.3914 -0.9931 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F06 mock treatment 9.1339562E7 -5940000.0 -0.3 9.2047802E7 -3610000.0 -0.19 -0.3526 -0.9765 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F07 mock treatment 8.9254872E7 -8020000.0 -0.41 9.3516319E7 -2140000.0 -0.12 -0.3723 -0.8716 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F08 mock treatment 8.4202418E7 -1.31E7 -0.67 8.3027688E7 -1.26E7 -0.68 -0.9548 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F09 mock treatment 8.0714148E7 -1.66E7 -0.85 8.2230679E7 -1.34E7 -0.72 -1.1115 -0.9968 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F10 mock treatment 7.8892521E7 -1.84E7 -0.94 8.0957084E7 -1.47E7 -0.79 -1.226 -0.9962 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F11 mock treatment 8.156385E7 -1.57E7 -0.81 7.943086E7 -1.62E7 -0.87 -1.1873 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F12 mock treatment 8.3265801E7 -1.4E7 -0.72 7.7597703E7 -1.81E7 -0.97 -1.1955 -0.9889 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F13 mock treatment 8.5108039E7 -1.22E7 -0.62 8.5179637E7 -1.05E7 -0.56 -0.84 -0.9987 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F14 mock treatment 8.9049695E7 -8230000.0 -0.42 8.6915111E7 -8740000.0 -0.47 -0.6311 -0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F15 mock treatment 8.9688326E7 -7590000.0 -0.39 8.7360809E7 -8290000.0 -0.45 -0.5909 -0.9976 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F16 mock treatment 9.3381605E7 -3900000.0 -0.2 8.954744E7 -6110000.0 -0.33 -0.3738 -0.9714 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F17 mock treatment 9.5601462E7 -1680000.0 -0.09 9.1684808E7 -3970000.0 -0.21 -0.212 -0.9198 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F18 mock treatment 9.9188581E7 1910000.0 0.1 9.6294094E7 639000.0 0.03 0.0935 0.9015 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F19 mock treatment 9.8703284E7 1420000.0 0.07 9.5504835E7 -151000.0 -0.01 0.0459 0.6246 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F20 mock treatment 1.01343723E8 4060000.0 0.21 1.05684331E8 1.0E7 0.54 0.5292 0.9142 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F21 mock treatment 1.01982229E8 4700000.0 0.24 1.03257184E8 7600000.0 0.41 0.4599 0.9681 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F22 mock treatment 1.05917528E8 8640000.0 0.44 1.05251053E8 9600000.0 0.52 0.6785 0.997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F23 mock treatment 1.05904276E8 8630000.0 0.44 1.03496919E8 7840000.0 0.42 0.6112 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base F24 mock treatment 1.21401014E8 2.41E7 1.24 1.21755037E8 2.61E7 1.41 1.868 0.998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G01 mock treatment 1.11761828E8 1.45E7 0.74 1.0572436E8 1.01E7 0.54 0.9083 0.9881 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G02 mock treatment 1.03675965E8 6400000.0 0.33 9.3385842E7 -2270000.0 -0.12 0.1454 0.4156 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G03 mock treatment 1.0278077E8 5500000.0 0.28 9.9136574E7 3480000.0 0.19 0.3319 0.9803 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G04 mock treatment 9.8532235E7 1250000.0 0.06 9.5158991E7 -497000.0 -0.03 0.0265 0.381 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G05 mock treatment 9.8298697E7 1020000.0 0.05 9.6232538E7 577000.0 0.03 0.0589 0.9691 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G06 mock treatment 9.455041E7 -2730000.0 -0.14 9.1204983E7 -4450000.0 -0.24 -0.2684 -0.9671 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G07 mock treatment 8.5926378E7 -1.14E7 -0.58 8.38661E7 -1.18E7 -0.63 -0.8603 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G08 mock treatment 8.5081986E7 -1.22E7 -0.63 8.9067615E7 -6590000.0 -0.35 -0.6929 -0.964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G09 mock treatment 8.0169158E7 -1.71E7 -0.88 8.1864066E7 -1.38E7 -0.74 -1.1452 -0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G10 mock treatment 8.0554765E7 -1.67E7 -0.86 8.2946356E7 -1.27E7 -0.68 -1.09 -0.9938 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G11 mock treatment 8.3259169E7 -1.4E7 -0.72 8.4399965E7 -1.13E7 -0.61 -0.9367 -0.9964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G12 mock treatment 8.2466657E7 -1.48E7 -0.76 8.0785599E7 -1.49E7 -0.8 -1.103 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G13 mock treatment 8.8012775E7 -9270000.0 -0.47 8.9962398E7 -5690000.0 -0.31 -0.5526 -0.9776 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G14 mock treatment 9.1679077E7 -5600000.0 -0.29 8.6456307E7 -9200000.0 -0.5 -0.5532 -0.9663 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G15 mock treatment 9.4896058E7 -2380000.0 -0.12 9.083738E7 -4820000.0 -0.26 -0.2698 -0.9409 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G16 mock treatment 9.5349442E7 -1930000.0 -0.1 9.2157503E7 -3500000.0 -0.19 -0.2031 -0.9547 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G17 mock treatment 9.6390786E7 -888000.0 -0.05 9.229398E7 -3360000.0 -0.18 -0.1602 -0.8582 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G18 mock treatment 9.967239E7 2390000.0 0.12 9.471083E7 -945000.0 -0.05 0.0508 0.3823 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G19 mock treatment 9.86912E7 1410000.0 0.07 9.6309694E7 654000.0 0.04 0.0761 0.9452 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G20 mock treatment 1.03192314E8 5910000.0 0.3 9.9035071E7 3380000.0 0.18 0.343 0.9702 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G21 mock treatment 1.05253437E8 7970000.0 0.41 1.01976275E8 6320000.0 0.34 0.5297 0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G22 mock treatment 1.11140711E8 1.39E7 0.71 1.06960032E8 1.13E7 0.61 0.9328 0.997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G23 mock treatment 1.16285427E8 1.9E7 0.97 1.09744618E8 1.41E7 0.76 1.2253 0.9924 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base G24 mock treatment 1.15595215E8 1.83E7 0.94 1.19401985E8 2.37E7 1.28 1.568 0.9884 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H01 mock treatment 1.0748962E8 1.02E7 0.52 1.04824647E8 9170000.0 0.49 0.7192 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H02 mock treatment 9.5987486E7 -1290000.0 -0.07 9.6673341E7 1020000.0 0.05 -0.008 -0.0936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H03 mock treatment 1.03198354E8 5920000.0 0.3 9.8528101E7 2870000.0 0.15 0.3239 0.9511 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H04 mock treatment 9.6877158E7 -402000.0 -0.02 9.2571919E7 -3080000.0 -0.17 -0.132 -0.7887 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H05 mock treatment 9.2674684E7 -4600000.0 -0.24 9.1602959E7 -4050000.0 -0.22 -0.3212 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H06 mock treatment 9.2178002E7 -5100000.0 -0.26 9.2871892E7 -2780000.0 -0.15 -0.2909 -0.9652 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H07 mock treatment 8.713496E7 -1.01E7 -0.52 8.70993E7 -8560000.0 -0.46 -0.6934 -0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H08 mock treatment 8.2399421E7 -1.49E7 -0.76 8.3032338E7 -1.26E7 -0.68 -1.0199 -0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H09 mock treatment 7.9590881E7 -1.77E7 -0.91 8.3843798E7 -1.18E7 -0.64 -1.0908 -0.985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H10 mock treatment 8.2099349E7 -1.52E7 -0.78 8.4284949E7 -1.14E7 -0.61 -0.9831 -0.993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H11 mock treatment 7.9253428E7 -1.8E7 -0.92 7.8562648E7 -1.71E7 -0.92 -1.3041 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H12 mock treatment 8.5006562E7 -1.23E7 -0.63 8.4101177E7 -1.16E7 -0.62 -0.8847 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H13 mock treatment 8.7306123E7 -9970000.0 -0.51 8.4623694E7 -1.1E7 -0.59 -0.7815 -0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H14 mock treatment 9.2485048E7 -4790000.0 -0.25 8.8579669E7 -7080000.0 -0.38 -0.4432 -0.9775 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H15 mock treatment 9.4628749E7 -2650000.0 -0.14 8.9432071E7 -6220000.0 -0.34 -0.333 -0.9209 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H16 mock treatment 9.4687511E7 -2590000.0 -0.13 9.3714627E7 -1940000.0 -0.1 -0.1678 -0.993 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H17 mock treatment 9.988151E7 2600000.0 0.13 9.4185285E7 -1470000.0 -0.08 0.0383 0.2471 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H18 mock treatment 9.7814618E7 536000.0 0.03 9.732216E7 1670000.0 0.09 0.0829 0.883 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H19 mock treatment 1.01796185E8 4520000.0 0.23 9.9301394E7 3650000.0 0.2 0.3025 0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H20 mock treatment 1.03263424E8 5980000.0 0.31 1.00215425E8 4560000.0 0.25 0.3905 0.9939 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H21 mock treatment 1.06489085E8 9210000.0 0.47 1.02622758E8 6970000.0 0.38 0.5991 0.9935 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H22 mock treatment 1.11010348E8 1.37E7 0.7 1.0605493E8 1.04E7 0.56 0.8936 0.9936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H23 mock treatment 1.12044067E8 1.48E7 0.76 1.14855952E8 1.92E7 1.03 1.2662 0.9882 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base H24 mock treatment 1.19274689E8 2.2E7 1.13 1.21347665E8 2.57E7 1.38 1.7755 0.9948 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I01 mock treatment 1.11418465E8 1.41E7 0.72 1.11179244E8 1.55E7 0.84 1.1035 0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I02 mock treatment 1.00664675E8 3390000.0 0.17 1.01284298E8 5630000.0 0.3 0.337 0.965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I03 mock treatment 1.03982335E8 6700000.0 0.34 1.00547377E8 4890000.0 0.26 0.4292 0.9914 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I04 mock treatment 1.00978579E8 3700000.0 0.19 9.9659518E7 4000000.0 0.22 0.2865 0.9979 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I05 mock treatment 9.4894905E7 -2380000.0 -0.12 9.2353486E7 -3300000.0 -0.18 -0.2121 -0.9832 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I06 mock treatment 9.0999043E7 -6280000.0 -0.32 9.0710929E7 -4940000.0 -0.27 -0.4159 -0.9956 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I07 mock treatment 8.829891E7 -8980000.0 -0.46 9.0448708E7 -5210000.0 -0.28 -0.5237 -0.9718 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I08 mock treatment 8.3005119E7 -1.43E7 -0.73 8.4277376E7 -1.14E7 -0.61 -0.9506 -0.9961 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I09 mock treatment 8.0680111E7 -1.66E7 -0.85 8.4054196E7 -1.16E7 -0.62 -1.0433 -0.9885 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I10 mock treatment 8.2644204E7 -1.46E7 -0.75 8.1337276E7 -1.43E7 -0.77 -1.0756 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I11 mock treatment 8.4316014E7 -1.3E7 -0.66 8.6963092E7 -8690000.0 -0.47 -0.8008 -0.9853 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I12 mock treatment 8.6355296E7 -1.09E7 -0.56 8.7021454E7 -8630000.0 -0.46 -0.7247 -0.9957 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I13 mock treatment 8.653997E7 -1.07E7 -0.55 8.3545525E7 -1.21E7 -0.65 -0.8503 -0.9964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I14 mock treatment 9.0971729E7 -6310000.0 -0.32 8.8798207E7 -6860000.0 -0.37 -0.4897 -0.9978 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I15 mock treatment 9.4751377E7 -2530000.0 -0.13 9.2755775E7 -2900000.0 -0.16 -0.202 -0.9957 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I16 mock treatment 9.4548384E7 -2730000.0 -0.14 9.1387969E7 -4270000.0 -0.23 -0.2615 -0.9717 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I17 mock treatment 9.7211221E7 -67600.0 0.0 9.336052E7 -2300000.0 -0.12 -0.0898 -0.7267 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I18 mock treatment 9.8745038E7 1470000.0 0.08 9.7660853E7 2010000.0 0.11 0.1295 0.9843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I19 mock treatment 1.01968741E8 4690000.0 0.24 9.8182946E7 2530000.0 0.14 0.2662 0.9637 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I20 mock treatment 1.04875936E8 7600000.0 0.39 1.01300487E8 5640000.0 0.3 0.4903 0.9925 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I21 mock treatment 1.06203704E8 8920000.0 0.46 9.9737134E7 4080000.0 0.22 0.4789 0.9436 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I22 mock treatment 1.08879589E8 1.16E7 0.59 1.05949779E8 1.03E7 0.55 0.8124 0.9994 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I23 mock treatment 1.10797191E8 1.35E7 0.69 1.12057976E8 1.64E7 0.88 1.1145 0.9928 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base I24 mock treatment 1.24646644E8 2.74E7 1.4 1.21545858E8 2.59E7 1.39 1.9777 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J01 mock treatment 1.13863819E8 1.66E7 0.85 1.11606579E8 1.6E7 0.86 1.2084 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J02 mock treatment 1.02649213E8 5370000.0 0.28 9.8989528E7 3330000.0 0.18 0.3216 0.9786 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J03 mock treatment 1.0347693E8 6200000.0 0.32 9.6564611E7 909000.0 0.05 0.2592 0.8066 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J04 mock treatment 9.7338665E7 59800.0 0.0 9.5239161E7 -416000.0 -0.02 -0.0137 -0.6048 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J05 mock treatment 9.8245604E7 967000.0 0.05 9.6352463E7 697000.0 0.04 0.0616 0.9906 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J06 mock treatment 9.3410586E7 -3870000.0 -0.2 9.4762749E7 -893000.0 -0.05 -0.1742 -0.8538 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J07 mock treatment 8.8508568E7 -8770000.0 -0.45 8.8698868E7 -6960000.0 -0.37 -0.5827 -0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J08 mock treatment 8.412244E7 -1.32E7 -0.67 8.5981476E7 -9670000.0 -0.52 -0.8452 -0.9919 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J09 mock treatment 8.4232609E7 -1.3E7 -0.67 8.7581056E7 -8070000.0 -0.43 -0.7803 -0.9783 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J10 mock treatment 8.3435155E7 -1.38E7 -0.71 8.542185E7 -1.02E7 -0.55 -0.8914 -0.9922 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J11 mock treatment 8.4830148E7 -1.24E7 -0.64 8.9616154E7 -6040000.0 -0.33 -0.6811 -0.9511 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J12 mock treatment 8.5740998E7 -1.15E7 -0.59 8.8878812E7 -6780000.0 -0.36 -0.6762 -0.9731 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J13 mock treatment 8.6429709E7 -1.08E7 -0.56 8.577933E7 -9880000.0 -0.53 -0.7693 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J14 mock treatment 9.0362304E7 -6920000.0 -0.35 8.9336274E7 -6320000.0 -0.34 -0.4913 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J15 mock treatment 9.2347747E7 -4930000.0 -0.25 9.0791438E7 -4860000.0 -0.26 -0.3639 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J16 mock treatment 9.3650685E7 -3630000.0 -0.19 9.0494064E7 -5160000.0 -0.28 -0.328 -0.9809 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J17 mock treatment 9.7065827E7 -213000.0 -0.01 9.5112111E7 -543000.0 -0.03 -0.0284 -0.9097 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J18 mock treatment 9.8317705E7 1040000.0 0.05 9.6451923E7 796000.0 0.04 0.068 0.9942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J19 mock treatment 1.00594981E8 3320000.0 0.17 9.9820246E7 4160000.0 0.22 0.2788 0.9906 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J20 mock treatment 1.03437775E8 6160000.0 0.32 1.02303257E8 6650000.0 0.36 0.4763 0.998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J21 mock treatment 1.05956015E8 8680000.0 0.44 1.02320183E8 6660000.0 0.36 0.5682 0.9943 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J22 mock treatment 1.10319534E8 1.3E7 0.67 1.02468509E8 6810000.0 0.37 0.732 0.9601 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J23 mock treatment 1.12867896E8 1.56E7 0.8 1.18347507E8 2.27E7 1.22 1.429 0.9788 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base J24 mock treatment 1.21535852E8 2.43E7 1.24 1.19275721E8 2.36E7 1.27 1.7785 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K01 mock treatment 1.12527431E8 1.52E7 0.78 1.12879017E8 1.72E7 0.93 1.2085 0.9964 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K02 mock treatment 1.0904414E8 1.18E7 0.6 1.01944841E8 6290000.0 0.34 0.6659 0.9628 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K03 mock treatment 1.0452356E8 7240000.0 0.37 9.7201235E7 1550000.0 0.08 0.3214 0.8447 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K04 mock treatment 1.02527529E8 5250000.0 0.27 9.8433694E7 2780000.0 0.15 0.296 0.9616 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K05 mock treatment 9.5990551E7 -1290000.0 -0.07 9.6990925E7 1340000.0 0.07 0.0042 0.0426 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K06 mock treatment 9.4620144E7 -2660000.0 -0.14 9.4612615E7 -1040000.0 -0.06 -0.1361 -0.9232 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K07 mock treatment 8.739593E7 -9880000.0 -0.51 9.3907204E7 -1750000.0 -0.09 -0.4247 -0.8244 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K08 mock treatment 8.5979813E7 -1.13E7 -0.58 8.6570105E7 -9090000.0 -0.49 -0.7554 -0.9965 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K09 mock treatment 8.4729617E7 -1.25E7 -0.64 9.0910236E7 -4750000.0 -0.26 -0.6355 -0.9182 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K10 mock treatment 8.1567737E7 -1.57E7 -0.81 8.8482081E7 -7170000.0 -0.39 -0.8425 -0.9434 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K11 mock treatment 8.6639105E7 -1.06E7 -0.55 9.2440492E7 -3220000.0 -0.17 -0.508 -0.8879 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K12 mock treatment 8.6222657E7 -1.11E7 -0.57 8.6523505E7 -9130000.0 -0.49 -0.7484 -0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K13 mock treatment 8.8835988E7 -8440000.0 -0.43 8.8017423E7 -7640000.0 -0.41 -0.5968 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K14 mock treatment 9.1025394E7 -6250000.0 -0.32 8.9199275E7 -6460000.0 -0.35 -0.4725 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K15 mock treatment 9.2543176E7 -4740000.0 -0.24 9.194889E7 -3710000.0 -0.2 -0.3128 -0.9953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K16 mock treatment 9.3854324E7 -3420000.0 -0.18 9.1264225E7 -4390000.0 -0.24 -0.2913 -0.9892 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K17 mock treatment 9.810492E7 826000.0 0.04 9.6956858E7 1300000.0 0.07 0.0795 0.9709 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K18 mock treatment 9.846973E7 1190000.0 0.06 9.8836837E7 3180000.0 0.17 0.1643 0.9034 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K19 mock treatment 1.00269664E8 2990000.0 0.15 1.0103916E8 5380000.0 0.29 0.3134 0.9556 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K20 mock treatment 1.06478649E8 9200000.0 0.47 1.01621035E8 5970000.0 0.32 0.5606 0.9825 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K21 mock treatment 1.05167592E8 7890000.0 0.4 1.02522103E8 6870000.0 0.37 0.5474 0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K22 mock treatment 1.08746949E8 1.15E7 0.59 1.02621469E8 6970000.0 0.38 0.6809 0.9765 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K23 mock treatment 1.09442221E8 1.22E7 0.62 1.0317817E8 7520000.0 0.41 0.7273 0.9782 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base K24 mock treatment 1.18919834E8 2.16E7 1.11 1.15936296E8 2.03E7 1.09 1.5565 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L01 mock treatment 1.09414168E8 1.21E7 0.62 1.12246329E8 1.66E7 0.89 1.0715 0.9843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L02 mock treatment 1.02644582E8 5370000.0 0.28 9.5278176E7 -377000.0 -0.02 0.1801 0.6531 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L03 mock treatment 1.03647772E8 6370000.0 0.33 1.03955877E8 8300000.0 0.45 0.5469 0.9881 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L04 mock treatment 9.8093531E7 815000.0 0.04 9.7231836E7 1580000.0 0.08 0.0895 0.9466 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L05 mock treatment 9.8553818E7 1270000.0 0.07 9.8052287E7 2400000.0 0.13 0.1375 0.9503 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L06 mock treatment 9.405006E7 -3230000.0 -0.17 9.4358682E7 -1300000.0 -0.07 -0.1664 -0.9264 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L07 mock treatment 9.2361811E7 -4920000.0 -0.25 9.1384523E7 -4270000.0 -0.23 -0.3408 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L08 mock treatment 8.6554917E7 -1.07E7 -0.55 8.7137968E7 -8520000.0 -0.46 -0.713 -0.996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L09 mock treatment 8.4329888E7 -1.29E7 -0.66 8.7653788E7 -8000000.0 -0.43 -0.774 -0.9781 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L10 mock treatment 8.7155471E7 -1.01E7 -0.52 9.436234E7 -1290000.0 -0.07 -0.4161 -0.7949 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L11 mock treatment 8.4539801E7 -1.27E7 -0.65 9.1827247E7 -3830000.0 -0.21 -0.6075 -0.8872 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L12 mock treatment 8.8744101E7 -8530000.0 -0.44 8.8723943E7 -6930000.0 -0.37 -0.5733 -0.9969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L13 mock treatment 9.042407E7 -6850000.0 -0.35 9.3498518E7 -2160000.0 -0.12 -0.3306 -0.8933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L14 mock treatment 9.3169271E7 -4110000.0 -0.21 9.108802E7 -4570000.0 -0.25 -0.3229 -0.997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L15 mock treatment 9.0626462E7 -6650000.0 -0.34 9.1485861E7 -4170000.0 -0.22 -0.3999 -0.9795 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L16 mock treatment 9.5839906E7 -1440000.0 -0.07 9.2596055E7 -3060000.0 -0.16 -0.1687 -0.9343 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L17 mock treatment 1.00981809E8 3700000.0 0.19 9.5189556E7 -466000.0 -0.03 0.1165 0.6083 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L18 mock treatment 9.8786697E7 1510000.0 0.08 9.7288805E7 1630000.0 0.09 0.1168 0.9979 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L19 mock treatment 1.02705156E8 5430000.0 0.28 1.02612726E8 6960000.0 0.37 0.4616 0.9892 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L20 mock treatment 1.07081666E8 9800000.0 0.5 1.05884336E8 1.02E7 0.55 0.7448 0.9989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L21 mock treatment 1.07171123E8 9890000.0 0.51 1.03518501E8 7860000.0 0.42 0.6579 0.996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L22 mock treatment 1.08938602E8 1.17E7 0.6 1.02762509E8 7110000.0 0.38 0.6932 0.9768 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L23 mock treatment 1.11868917E8 1.46E7 0.75 1.08227928E8 1.26E7 0.68 1.0075 0.9988 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base L24 mock treatment 1.20313987E8 2.3E7 1.18 1.17432836E8 2.18E7 1.17 1.6641 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M01 mock treatment 1.19648371E8 2.24E7 1.15 1.23773919E8 2.81E7 1.51 1.8814 0.9906 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M02 mock treatment 1.00857573E8 3580000.0 0.18 1.04793095E8 9140000.0 0.49 0.4776 0.9095 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M03 mock treatment 1.03148758E8 5870000.0 0.3 9.8521057E7 2870000.0 0.15 0.3218 0.9519 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M04 mock treatment 1.02588031E8 5310000.0 0.27 1.0044887E8 4790000.0 0.26 0.3749 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M05 mock treatment 9.874149E7 1460000.0 0.07 9.8328774E7 2670000.0 0.14 0.1548 0.9538 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M06 mock treatment 9.2736017E7 -4540000.0 -0.23 9.7434498E7 1780000.0 0.1 -0.0969 -0.3849 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M07 mock treatment 8.9578676E7 -7700000.0 -0.39 8.9636233E7 -6020000.0 -0.32 -0.5083 -0.9952 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M08 mock treatment 9.2612482E7 -4670000.0 -0.24 9.6664628E7 1010000.0 0.05 -0.1307 -0.5329 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M09 mock treatment 8.6026255E7 -1.13E7 -0.58 9.1403071E7 -4250000.0 -0.23 -0.5697 -0.9181 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M10 mock treatment 8.5446463E7 -1.18E7 -0.61 8.9827342E7 -5830000.0 -0.31 -0.6507 -0.953 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M11 mock treatment 8.5121664E7 -1.22E7 -0.62 9.1486115E7 -4170000.0 -0.22 -0.5994 -0.905 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M12 mock treatment 8.744158E7 -9840000.0 -0.5 9.2736295E7 -2920000.0 -0.16 -0.4677 -0.8855 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M13 mock treatment 9.2233956E7 -5040000.0 -0.26 9.1773975E7 -3880000.0 -0.21 -0.3306 -0.9944 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M14 mock treatment 9.0732191E7 -6550000.0 -0.34 9.4171782E7 -1480000.0 -0.08 -0.2938 -0.8517 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M15 mock treatment 9.1338356E7 -5940000.0 -0.3 9.1835793E7 -3820000.0 -0.21 -0.3607 -0.9818 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M16 mock treatment 9.1571298E7 -5710000.0 -0.29 9.3184299E7 -2470000.0 -0.13 -0.301 -0.9364 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M17 mock treatment 9.3811817E7 -3470000.0 -0.18 9.472154E7 -934000.0 -0.05 -0.1612 -0.873 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M18 mock treatment 9.7664492E7 386000.0 0.02 9.8081907E7 2430000.0 0.13 0.1064 0.8049 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M19 mock treatment 9.9219071E7 1940000.0 0.1 1.00168182E8 4510000.0 0.24 0.2421 0.9222 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M20 mock treatment 1.01967667E8 4690000.0 0.24 1.02775165E8 7120000.0 0.38 0.441 0.9747 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M21 mock treatment 1.09201699E8 1.19E7 0.61 1.11368028E8 1.57E7 0.85 1.0304 0.9872 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M22 mock treatment 1.13214894E8 1.59E7 0.82 1.03898027E8 8240000.0 0.44 0.8914 0.9589 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M23 mock treatment 1.11376924E8 1.41E7 0.72 1.09464333E8 1.38E7 0.74 1.0367 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base M24 mock treatment 1.1581325E8 1.85E7 0.95 1.12552547E8 1.69E7 0.91 1.3151 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N01 mock treatment 1.14409384E8 1.71E7 0.88 1.08341405E8 1.27E7 0.68 1.1039 0.9923 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N02 mock treatment 1.10319812E8 1.3E7 0.67 1.12950265E8 1.73E7 0.93 1.1312 0.9868 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N03 mock treatment 1.03679471E8 6400000.0 0.33 1.01524161E8 5870000.0 0.32 0.4554 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N04 mock treatment 1.02982575E8 5700000.0 0.29 9.9518682E7 3860000.0 0.21 0.3538 0.9861 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N05 mock treatment 9.4098734E7 -3180000.0 -0.16 9.7566972E7 1910000.0 0.1 -0.0425 -0.2203 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N06 mock treatment 9.0965723E7 -6310000.0 -0.32 9.4664239E7 -991000.0 -0.05 -0.2665 -0.8128 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N07 mock treatment 9.0978396E7 -6300000.0 -0.32 9.3363605E7 -2290000.0 -0.12 -0.3156 -0.913 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N08 mock treatment 8.8682941E7 -8600000.0 -0.44 9.3774501E7 -1880000.0 -0.1 -0.3832 -0.8476 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N09 mock treatment 8.9996933E7 -7280000.0 -0.37 9.2365023E7 -3290000.0 -0.18 -0.3892 -0.942 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N10 mock treatment 8.7966118E7 -9310000.0 -0.48 9.3833479E7 -1820000.0 -0.1 -0.4069 -0.835 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N11 mock treatment 8.7137539E7 -1.01E7 -0.52 9.5407895E7 -248000.0 -0.01 -0.377 -0.725 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N12 mock treatment 9.0782362E7 -6500000.0 -0.33 9.258476E7 -3070000.0 -0.17 -0.3524 -0.9478 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N13 mock treatment 8.8580788E7 -8700000.0 -0.45 9.265405E7 -3000000.0 -0.16 -0.4295 -0.9058 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N14 mock treatment 9.1626662E7 -5650000.0 -0.29 8.9491652E7 -6160000.0 -0.33 -0.4396 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N15 mock treatment 8.9289924E7 -7990000.0 -0.41 9.7455489E7 1800000.0 0.1 -0.221 -0.5252 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N16 mock treatment 9.3168023E7 -4110000.0 -0.21 9.5757945E7 102000.0 0.01 -0.1451 -0.6884 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N17 mock treatment 1.01157337E8 3880000.0 0.2 9.739079E7 1740000.0 0.09 0.2066 0.9407 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N18 mock treatment 9.6337018E7 -942000.0 -0.05 1.01118182E8 5460000.0 0.29 0.1739 0.5833 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N19 mock treatment 1.00955258E8 3680000.0 0.19 9.6163773E7 508000.0 0.03 0.1526 0.8014 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N20 mock treatment 1.05829597E8 8550000.0 0.44 1.08949861E8 1.33E7 0.72 0.8161 0.9723 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N21 mock treatment 1.109774E8 1.37E7 0.7 9.7118704E7 1460000.0 0.08 0.5522 0.7816 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N22 mock treatment 1.15641721E8 1.84E7 0.94 1.03208922E8 7550000.0 0.41 0.9531 0.9296 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N23 mock treatment 1.09834903E8 1.26E7 0.64 1.05611499E8 9960000.0 0.54 0.8341 0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base N24 mock treatment 1.22381654E8 2.51E7 1.29 1.18545978E8 2.29E7 1.23 1.7814 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O01 mock treatment 1.19454311E8 2.22E7 1.14 1.17635334E8 2.2E7 1.18 1.6406 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O02 mock treatment 1.08074385E8 1.08E7 0.55 1.05722615E8 1.01E7 0.54 0.7746 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O03 mock treatment 1.0356338E8 6280000.0 0.32 1.02613698E8 6960000.0 0.37 0.4927 0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O04 mock treatment 9.8831336E7 1550000.0 0.08 1.06512456E8 1.09E7 0.58 0.4697 0.796 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O05 mock treatment 9.6265507E7 -1010000.0 -0.05 1.02093784E8 6440000.0 0.35 0.2084 0.5945 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O06 mock treatment 9.3651255E7 -3630000.0 -0.19 1.01037973E8 5380000.0 0.29 0.0735 0.2134 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O07 mock treatment 9.2871658E7 -4410000.0 -0.23 9.6789477E7 1130000.0 0.06 -0.1165 -0.4981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O08 mock treatment 8.899791E7 -8280000.0 -0.42 9.4604639E7 -1050000.0 -0.06 -0.3401 -0.7944 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O09 mock treatment 9.0561425E7 -6720000.0 -0.34 9.4969595E7 -686000.0 -0.04 -0.2696 -0.7785 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O10 mock treatment 8.9943308E7 -7340000.0 -0.38 9.4415106E7 -1240000.0 -0.07 -0.3131 -0.8199 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O11 mock treatment 9.0129829E7 -7150000.0 -0.37 9.5667799E7 12200.0 0.0 -0.2586 -0.7058 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O12 mock treatment 9.4199043E7 -3080000.0 -0.16 9.7499759E7 1840000.0 0.1 -0.0414 -0.222 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O13 mock treatment 9.281332E7 -4470000.0 -0.23 9.629751E7 642000.0 0.03 -0.1374 -0.5936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O14 mock treatment 9.3190983E7 -4090000.0 -0.21 9.8397762E7 2740000.0 0.15 -0.0437 -0.1706 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O15 mock treatment 9.3459082E7 -3820000.0 -0.2 9.8609255E7 2950000.0 0.16 -0.026 -0.1029 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O16 mock treatment 9.2665E7 -4610000.0 -0.24 9.9746645E7 4090000.0 0.22 -0.0114 -0.0354 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O17 mock treatment 9.983365E7 2550000.0 0.13 9.9210922E7 3560000.0 0.19 0.228 0.9828 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O18 mock treatment 1.00699321E8 3420000.0 0.18 1.02645305E8 6990000.0 0.38 0.3901 0.9395 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O19 mock treatment 9.8289257E7 1010000.0 0.05 1.02745385E8 7090000.0 0.38 0.3066 0.7957 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O20 mock treatment 1.02070434E8 4790000.0 0.25 9.4127822E7 -1530000.0 -0.08 0.1155 0.4459 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O21 mock treatment 1.11768594E8 1.45E7 0.74 1.15501187E8 1.98E7 1.07 1.2808 0.9842 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O22 mock treatment 1.10694867E8 1.34E7 0.69 1.05627689E8 9970000.0 0.54 0.8659 0.9925 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O23 mock treatment 1.13581456E8 1.63E7 0.84 1.09161868E8 1.35E7 0.73 1.1051 0.9976 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base O24 mock treatment 1.20868555E8 2.36E7 1.21 1.24730396E8 2.91E7 1.57 1.962 0.9918 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P01 mock treatment 1.21739472E8 2.45E7 1.25 1.19448803E8 2.38E7 1.28 1.7925 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P02 mock treatment 1.13403559E8 1.61E7 0.83 1.14026164E8 1.84E7 0.99 1.2839 0.996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P03 mock treatment 1.11490359E8 1.42E7 0.73 1.07642621E8 1.2E7 0.65 0.9715 0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P04 mock treatment 1.05276929E8 8000000.0 0.41 1.03612331E8 7960000.0 0.43 0.5928 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P05 mock treatment 9.7608761E7 330000.0 0.02 1.01547256E8 5890000.0 0.32 0.2363 0.7437 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P06 mock treatment 9.8535689E7 1260000.0 0.06 1.07877029E8 1.22E7 0.66 0.5109 0.7726 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P07 mock treatment 9.6449207E7 -830000.0 -0.04 1.03962198E8 8310000.0 0.45 0.2862 0.637 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P08 mock treatment 9.4214802E7 -3060000.0 -0.16 1.01776827E8 6120000.0 0.33 0.122 0.3342 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P09 mock treatment 9.7151945E7 -127000.0 -0.01 1.01692206E8 6040000.0 0.33 0.2253 0.6928 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P10 mock treatment 9.6000658E7 -1280000.0 -0.07 1.01772322E8 6120000.0 0.33 0.1866 0.5556 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P11 mock treatment 9.6544117E7 -735000.0 -0.04 9.6923447E7 1270000.0 0.07 0.0217 0.2777 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P12 mock treatment 1.00091152E8 2810000.0 0.14 9.8275144E7 2620000.0 0.14 0.2017 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P13 mock treatment 1.0132924E8 4050000.0 0.21 1.03839038E8 8180000.0 0.44 0.4584 0.941 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P14 mock treatment 9.9592652E7 2310000.0 0.12 9.8420638E7 2770000.0 0.15 0.1891 0.9936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P15 mock treatment 9.9373657E7 2090000.0 0.11 1.01689931E8 6030000.0 0.32 0.3057 0.8932 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P16 mock treatment 1.05030892E8 7750000.0 0.4 1.0118169E8 5530000.0 0.3 0.4914 0.9899 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P17 mock treatment 1.04744882E8 7470000.0 0.38 1.05906812E8 1.03E7 0.55 0.6609 0.984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P18 mock treatment 1.0355514E8 6280000.0 0.32 1.06603634E8 1.09E7 0.59 0.6443 0.9594 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P19 mock treatment 1.05634083E8 8360000.0 0.43 1.1581233E8 2.02E7 1.09 1.0703 0.9173 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P20 mock treatment 1.08980096E8 1.17E7 0.6 1.07171192E8 1.15E7 0.62 0.8626 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P21 mock treatment 1.11218402E8 1.39E7 0.71 1.13328863E8 1.77E7 0.95 1.1782 0.99 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P22 mock treatment 1.13404243E8 1.61E7 0.83 1.12780283E8 1.71E7 0.92 1.2365 0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P23 mock treatment 1.21410234E8 2.41E7 1.24 1.17282563E8 2.16E7 1.16 1.6981 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.Base P24 mock treatment 1.31282319E8 3.4E7 1.74 1.27016917E8 3.14E7 1.69 2.4265 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A01 positive control 3.5622057E7 -5.71E7 -2.93 3.5208911E7 -5.58E7 -3.01 -4.1974 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A02 positive control 3.4247408E7 -5.85E7 -3.0 3.3625046E7 -5.74E7 -3.09 -4.3075 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A03 positive control 3.3701039E7 -5.91E7 -3.03 3.2620654E7 -5.84E7 -3.15 -4.3655 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A04 positive control 3.8575791E7 -5.42E7 -2.78 3.7815494E7 -5.32E7 -2.87 -3.9911 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A05 positive control 3.4197394E7 -5.86E7 -3.0 3.2190949E7 -5.89E7 -3.17 -4.3639 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A06 positive control 3.4289331E7 -5.85E7 -3.0 3.2028016E7 -5.9E7 -3.18 -4.3668 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A07 positive control 3.3213391E7 -5.96E7 -3.05 3.1547197E7 -5.95E7 -3.2 -4.4241 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A08 positive control 3.2840496E7 -5.99E7 -3.07 3.22796E7 -5.88E7 -3.16 -4.4097 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A09 positive control 3.300874E7 -5.98E7 -3.06 3.0920927E7 -6.01E7 -3.24 -4.4553 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A10 positive control 3.3312152E7 -5.95E7 -3.05 3.1871051E7 -5.92E7 -3.19 -4.4082 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A11 positive control 3.2820323E7 -6.0E7 -3.07 3.1567166E7 -5.95E7 -3.2 -4.4376 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A12 positive control 3.3152596E7 -5.96E7 -3.06 3.101976E7 -6.0E7 -3.23 -4.4464 -0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A13 mock treatment 8.5956325E7 -6810000.0 -0.35 8.4618915E7 -6430000.0 -0.35 -0.4917 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A14 mock treatment 8.8861547E7 -3910000.0 -0.2 7.6886895E7 -1.42E7 -0.76 -0.6809 -0.8636 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A15 mock treatment 9.0220992E7 -2550000.0 -0.13 7.5853311E7 -1.52E7 -0.82 -0.671 -0.8098 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A16 mock treatment 9.2214997E7 -556000.0 -0.03 8.7685852E7 -3360000.0 -0.18 -0.1481 -0.8085 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A17 mock treatment 9.6216806E7 3450000.0 0.18 8.5589738E7 -5460000.0 -0.29 -0.0829 -0.2419 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A18 mock treatment 1.02639054E8 9870000.0 0.51 9.8083846E7 7040000.0 0.38 0.6256 0.9899 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A19 mock treatment 9.853603E7 5760000.0 0.3 8.9942847E7 -1100000.0 -0.06 0.1669 0.5537 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A20 mock treatment 1.00648691E8 7880000.0 0.4 9.0753211E7 -294000.0 -0.02 0.2743 0.6789 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A21 mock treatment 9.4403819E7 1630000.0 0.08 9.0295585E7 -751000.0 -0.04 0.0306 0.3288 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A22 mock treatment 1.05803333E8 1.3E7 0.67 1.04119092E8 1.31E7 0.7 0.9701 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A23 mock treatment 1.10773619E8 1.8E7 0.92 1.05803124E8 1.48E7 0.79 1.2143 0.9972 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon A24 mock treatment 1.15291698E8 2.25E7 1.15 1.13266751E8 2.22E7 1.2 1.6623 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B01 positive control 3.777295E7 -5.5E7 -2.82 3.7462433E7 -5.36E7 -2.89 -4.0336 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B02 positive control 3.1346085E7 -6.14E7 -3.15 3.1684662E7 -5.94E7 -3.2 -4.4865 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B03 positive control 3.2287786E7 -6.05E7 -3.1 3.0843528E7 -6.02E7 -3.24 -4.4844 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B04 positive control 3.1644837E7 -6.11E7 -3.13 3.0127291E7 -6.09E7 -3.28 -4.535 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B05 positive control 3.0234567E7 -6.25E7 -3.21 3.0678424E7 -6.04E7 -3.25 -4.5651 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B06 positive control 3.1122147E7 -6.16E7 -3.16 2.9814086E7 -6.12E7 -3.3 -4.5659 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B07 positive control 3.0686407E7 -6.21E7 -3.18 3.0611826E7 -6.04E7 -3.25 -4.5513 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B08 positive control 3.1592036E7 -6.12E7 -3.14 2.9761364E7 -6.13E7 -3.3 -4.5508 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B09 positive control 3.0864976E7 -6.19E7 -3.17 3.0607651E7 -6.04E7 -3.25 -4.545 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B10 positive control 3.0553434E7 -6.22E7 -3.19 2.9097953E7 -6.19E7 -3.34 -4.6137 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B11 positive control 3.0331774E7 -6.24E7 -3.2 2.957654E7 -6.15E7 -3.31 -4.6036 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B12 positive control 3.0228711E7 -6.25E7 -3.21 2.9937102E7 -6.11E7 -3.29 -4.5936 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B13 mock treatment 7.8017836E7 -1.48E7 -0.76 7.2246049E7 -1.88E7 -1.01 -1.2506 -0.9897 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B14 mock treatment 7.9366707E7 -1.34E7 -0.69 6.9397358E7 -2.16E7 -1.17 -1.3102 -0.9682 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B15 mock treatment 8.3202113E7 -9570000.0 -0.49 7.0100763E7 -2.09E7 -1.13 -1.1444 -0.9304 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B16 mock treatment 8.6606052E7 -6170000.0 -0.32 7.9057805E7 -1.2E7 -0.65 -0.68 -0.946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B17 mock treatment 8.5631756E7 -7140000.0 -0.37 7.5437595E7 -1.56E7 -0.84 -0.8531 -0.9306 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B18 mock treatment 8.9793232E7 -2980000.0 -0.15 7.7830603E7 -1.32E7 -0.71 -0.6112 -0.8397 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B19 mock treatment 9.1752194E7 -1020000.0 -0.05 8.1929372E7 -9120000.0 -0.49 -0.3841 -0.7779 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B20 mock treatment 1.01549347E8 8780000.0 0.45 9.7165343E7 6120000.0 0.33 0.5511 0.9883 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B21 mock treatment 9.5224609E7 2450000.0 0.13 8.9513235E7 -1530000.0 -0.08 0.0305 0.2029 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B22 mock treatment 9.853566E7 5760000.0 0.3 9.0216141E7 -831000.0 -0.04 0.1773 0.5933 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B23 mock treatment 1.07022869E8 1.43E7 0.73 9.9739398E7 8690000.0 0.47 0.8475 0.9769 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon B24 mock treatment 1.15916927E8 2.31E7 1.19 1.03430055E8 1.24E7 0.67 1.3104 0.9629 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C01 positive control 3.4119116E7 -5.87E7 -3.01 3.3722419E7 -5.73E7 -3.09 -4.3084 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C02 positive control 3.2671716E7 -6.01E7 -3.08 3.2107133E7 -5.89E7 -3.17 -4.4224 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C03 positive control 3.261852E7 -6.02E7 -3.08 3.14995E7 -5.95E7 -3.21 -4.4475 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C04 positive control 3.1853819E7 -6.09E7 -3.12 3.0661943E7 -6.04E7 -3.25 -4.5071 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C05 positive control 3.0966409E7 -6.18E7 -3.17 3.0443018E7 -6.06E7 -3.26 -4.5476 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C06 positive control 3.0677936E7 -6.21E7 -3.18 3.0410503E7 -6.06E7 -3.27 -4.5593 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C07 positive control 3.1013171E7 -6.18E7 -3.17 3.1510626E7 -5.95E7 -3.21 -4.5052 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C08 positive control 3.1198252E7 -6.16E7 -3.16 3.0609564E7 -6.04E7 -3.25 -4.5328 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C09 positive control 3.2010077E7 -6.08E7 -3.11 3.2395099E7 -5.87E7 -3.16 -4.4354 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C10 positive control 3.0514415E7 -6.23E7 -3.19 3.0062899E7 -6.1E7 -3.28 -4.5784 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C11 positive control 3.0045106E7 -6.27E7 -3.21 3.0483831E7 -6.06E7 -3.26 -4.5794 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C12 positive control 3.0479448E7 -6.23E7 -3.19 2.9849446E7 -6.12E7 -3.3 -4.5878 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C13 mock treatment 7.2902509E7 -1.99E7 -1.02 7.3690874E7 -1.74E7 -0.93 -1.3809 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C14 mock treatment 7.5307057E7 -1.75E7 -0.9 6.8139855E7 -2.29E7 -1.23 -1.5052 -0.9876 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C15 mock treatment 7.8906992E7 -1.39E7 -0.71 6.6667201E7 -2.44E7 -1.31 -1.4308 -0.9584 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C16 mock treatment 8.0413984E7 -1.24E7 -0.63 6.5814378E7 -2.52E7 -1.36 -1.4086 -0.9396 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C17 mock treatment 8.6683478E7 -6090000.0 -0.31 8.3741166E7 -7310000.0 -0.39 -0.4988 -0.9934 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C18 mock treatment 8.6674879E7 -6100000.0 -0.31 7.801634E7 -1.3E7 -0.7 -0.7171 -0.9336 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C19 mock treatment 8.7627644E7 -5140000.0 -0.26 8.0624828E7 -1.04E7 -0.56 -0.5833 -0.9406 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C20 mock treatment 9.0720982E7 -2050000.0 -0.11 8.7428836E7 -3620000.0 -0.19 -0.2121 -0.958 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C21 mock treatment 9.4523185E7 1750000.0 0.09 9.0045856E7 -1000000.0 -0.05 0.0254 0.2423 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C22 mock treatment 9.5543411E7 2770000.0 0.14 9.5014346E7 3970000.0 0.21 0.2515 0.9804 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C23 mock treatment 1.04620464E8 1.18E7 0.61 9.5774398E7 4730000.0 0.25 0.6094 0.9255 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon C24 mock treatment 1.121347E8 1.94E7 0.99 1.06665779E8 1.56E7 0.84 1.2965 0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D01 positive control 3.2162604E7 -6.06E7 -3.11 3.2142806E7 -5.89E7 -3.17 -4.4395 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D02 positive control 3.1618046E7 -6.12E7 -3.13 3.055129E7 -6.05E7 -3.26 -4.5198 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D03 positive control 3.15953E7 -6.12E7 -3.14 3.071973E7 -6.03E7 -3.25 -4.5142 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D04 positive control 3.113893E7 -6.16E7 -3.16 3.0502013E7 -6.05E7 -3.26 -4.5391 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D05 positive control 3.0307805E7 -6.25E7 -3.2 3.0359504E7 -6.07E7 -3.27 -4.5746 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D06 positive control 3.0475219E7 -6.23E7 -3.19 3.0151061E7 -6.09E7 -3.28 -4.5765 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D07 positive control 3.0765542E7 -6.2E7 -3.18 3.0849166E7 -6.02E7 -3.24 -4.5394 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D08 positive control 3.0860726E7 -6.19E7 -3.17 3.1101706E7 -5.99E7 -3.23 -4.5263 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D09 positive control 3.0148104E7 -6.26E7 -3.21 3.0425856E7 -6.06E7 -3.26 -4.5779 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D10 positive control 2.9619545E7 -6.32E7 -3.24 2.9747265E7 -6.13E7 -3.3 -4.6229 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D11 positive control 3.0117437E7 -6.27E7 -3.21 2.994158E7 -6.11E7 -3.29 -4.5974 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D12 positive control 3.0627912E7 -6.21E7 -3.19 3.1629829E7 -5.94E7 -3.2 -4.5146 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D13 mock treatment 7.0608459E7 -2.22E7 -1.14 8.0888384E7 -1.02E7 -0.55 -1.19 -0.9439 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D14 mock treatment 7.434395E7 -1.84E7 -0.94 6.9694277E7 -2.14E7 -1.15 -1.4809 -0.9952 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D15 mock treatment 7.7727645E7 -1.5E7 -0.77 6.9341532E7 -2.17E7 -1.17 -1.3717 -0.9796 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D16 mock treatment 8.7319252E7 -5450000.0 -0.28 7.820184E7 -1.28E7 -0.69 -0.6867 -0.9205 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D17 mock treatment 7.9664072E7 -1.31E7 -0.67 7.559507E7 -1.55E7 -0.83 -1.0634 -0.9944 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D18 mock treatment 8.9049468E7 -3720000.0 -0.19 8.6862994E7 -4180000.0 -0.23 -0.2942 -0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D19 mock treatment 8.593724E7 -6830000.0 -0.35 8.4543373E7 -6500000.0 -0.35 -0.4953 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D20 mock treatment 9.1367129E7 -1400000.0 -0.07 8.4817341E7 -6230000.0 -0.34 -0.2881 -0.8397 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D21 mock treatment 9.283546E7 64300.0 0.0 8.7306968E7 -3740000.0 -0.2 -0.1401 -0.6954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D22 mock treatment 9.4487919E7 1720000.0 0.09 9.5821931E7 4780000.0 0.26 0.244 0.8979 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D23 mock treatment 1.03098756E8 1.03E7 0.53 9.3953023E7 2910000.0 0.16 0.4849 0.8786 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon D24 mock treatment 1.06566966E8 1.38E7 0.71 1.01113716E8 1.01E7 0.54 0.8833 0.9914 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E01 positive control 3.2808529E7 -6.0E7 -3.07 3.2572201E7 -5.85E7 -3.15 -4.3997 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E02 positive control 3.1356279E7 -6.14E7 -3.15 3.2386548E7 -5.87E7 -3.16 -4.4594 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E03 positive control 3.3545767E7 -5.92E7 -3.04 3.3851714E7 -5.72E7 -3.08 -4.3243 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E04 positive control 3.1081014E7 -6.17E7 -3.16 3.1184434E7 -5.99E7 -3.22 -4.5152 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E05 positive control 3.055245E7 -6.22E7 -3.19 3.1075377E7 -6.0E7 -3.23 -4.5385 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E06 positive control 3.269315E7 -6.01E7 -3.08 3.2609425E7 -5.84E7 -3.15 -4.4025 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E07 positive control 3.0367974E7 -6.24E7 -3.2 3.0885714E7 -6.02E7 -3.24 -4.5524 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E08 positive control 3.0674726E7 -6.21E7 -3.18 3.0772401E7 -6.03E7 -3.25 -4.5456 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E09 positive control 3.1059131E7 -6.17E7 -3.16 3.0452789E7 -6.06E7 -3.26 -4.5438 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E10 positive control 3.0513031E7 -6.23E7 -3.19 3.1037382E7 -6.0E7 -3.23 -4.5414 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E11 positive control 2.9772997E7 -6.3E7 -3.23 3.0650099E7 -6.04E7 -3.25 -4.5829 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E12 positive control 3.0462239E7 -6.23E7 -3.19 3.1194659E7 -5.99E7 -3.22 -4.5372 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E13 mock treatment 7.3964017E7 -1.88E7 -0.96 7.959948E7 -1.14E7 -0.62 -1.1175 -0.9767 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E14 mock treatment 7.4862025E7 -1.79E7 -0.92 7.6990995E7 -1.41E7 -0.76 -1.1843 -0.9954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E15 mock treatment 7.7743869E7 -1.5E7 -0.77 7.4273726E7 -1.68E7 -0.9 -1.1833 -0.9969 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E16 mock treatment 8.0007251E7 -1.28E7 -0.65 7.5088906E7 -1.6E7 -0.86 -1.0702 -0.9909 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E17 mock treatment 8.3851998E7 -8920000.0 -0.46 8.2631644E7 -8420000.0 -0.45 -0.6437 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E18 mock treatment 8.7845744E7 -4930000.0 -0.25 8.685549E7 -4190000.0 -0.23 -0.3381 -0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E19 mock treatment 9.0096893E7 -2670000.0 -0.14 8.9946203E7 -1100000.0 -0.06 -0.1388 -0.9297 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E20 mock treatment 9.1627555E7 -1140000.0 -0.06 9.4774807E7 3730000.0 0.2 0.1005 0.4806 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E21 mock treatment 9.3938248E7 1170000.0 0.06 9.1913363E7 867000.0 0.05 0.0753 0.9925 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E22 mock treatment 1.0258533E8 9810000.0 0.5 1.02465613E8 1.14E7 0.61 0.7905 0.995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E23 mock treatment 9.7321537E7 4550000.0 0.23 9.5669642E7 4620000.0 0.25 0.3409 0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon E24 mock treatment 1.14158604E8 2.14E7 1.1 1.04861421E8 1.38E7 0.74 1.3011 0.9822 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F01 positive control 3.3416981E7 -5.94E7 -3.04 3.4196155E7 -5.69E7 -3.06 -4.3158 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F02 positive control 3.3638391E7 -5.91E7 -3.03 3.4475888E7 -5.66E7 -3.05 -4.2972 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F03 positive control 3.056105E7 -6.22E7 -3.19 3.0839936E7 -6.02E7 -3.24 -4.5471 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F04 positive control 3.0470911E7 -6.23E7 -3.19 3.1338158E7 -5.97E7 -3.22 -4.5314 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F05 positive control 3.0898297E7 -6.19E7 -3.17 3.1865803E7 -5.92E7 -3.19 -4.4959 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F06 positive control 3.0635553E7 -6.21E7 -3.18 3.0487121E7 -6.06E7 -3.26 -4.5579 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F07 positive control 3.2100964E7 -6.07E7 -3.11 3.2542871E7 -5.85E7 -3.15 -4.4265 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F08 positive control 2.993767E7 -6.28E7 -3.22 3.0683546E7 -6.04E7 -3.25 -4.5757 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F09 positive control 3.0526182E7 -6.22E7 -3.19 3.0469326E7 -6.06E7 -3.26 -4.5625 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F10 positive control 2.9817956E7 -6.3E7 -3.23 3.0193584E7 -6.09E7 -3.28 -4.5987 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F11 positive control 3.0063474E7 -6.27E7 -3.21 3.0523572E7 -6.05E7 -3.26 -4.5772 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F12 positive control 2.9632959E7 -6.31E7 -3.24 3.0585412E7 -6.05E7 -3.26 -4.5905 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F13 mock treatment 7.6410297E7 -1.64E7 -0.84 8.0637903E7 -1.04E7 -0.56 -0.9893 -0.9808 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F14 mock treatment 7.91759E7 -1.36E7 -0.7 8.0083661E7 -1.1E7 -0.59 -0.9102 -0.9966 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F15 mock treatment 7.8995324E7 -1.38E7 -0.71 7.9019228E7 -1.2E7 -0.65 -0.9572 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F16 mock treatment 8.2469598E7 -1.03E7 -0.53 7.6894244E7 -1.42E7 -0.76 -0.9122 -0.9839 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F17 mock treatment 8.7146364E7 -5620000.0 -0.29 8.3812717E7 -7230000.0 -0.39 -0.4793 -0.989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F18 mock treatment 8.6475978E7 -6300000.0 -0.32 8.4547926E7 -6500000.0 -0.35 -0.4756 -0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F19 mock treatment 8.9471913E7 -3300000.0 -0.17 9.0409261E7 -638000.0 -0.03 -0.1438 -0.8337 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F20 mock treatment 9.8141664E7 5370000.0 0.28 9.5918748E7 4870000.0 0.26 0.3801 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F21 mock treatment 9.6944087E7 4170000.0 0.21 9.6800139E7 5750000.0 0.31 0.3703 0.9836 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F22 mock treatment 9.7819587E7 5050000.0 0.26 9.6413447E7 5370000.0 0.29 0.3873 0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F23 mock treatment 9.8791642E7 6020000.0 0.31 1.00401439E8 9350000.0 0.5 0.5744 0.9723 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon F24 mock treatment 1.20116561E8 2.73E7 1.4 1.14247625E8 2.32E7 1.25 1.8745 0.9984 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G01 positive control 3.3744484E7 -5.9E7 -3.03 3.2667806E7 -5.84E7 -3.14 -4.3622 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G02 positive control 3.2038364E7 -6.07E7 -3.11 3.2740529E7 -5.83E7 -3.14 -4.4212 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G03 positive control 3.1534799E7 -6.12E7 -3.14 3.1713718E7 -5.93E7 -3.2 -4.4786 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G04 positive control 3.1961849E7 -6.08E7 -3.12 3.2069494E7 -5.9E7 -3.18 -4.4496 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G05 positive control 3.1861628E7 -6.09E7 -3.12 3.2547112E7 -5.85E7 -3.15 -4.435 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G06 positive control 3.197234E7 -6.08E7 -3.12 3.2394952E7 -5.87E7 -3.16 -4.4368 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G07 positive control 3.0796118E7 -6.2E7 -3.18 3.1015154E7 -6.0E7 -3.23 -4.5319 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G08 positive control 3.1699993E7 -6.11E7 -3.13 3.2055936E7 -5.9E7 -3.18 -4.4596 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G09 positive control 3.0476994E7 -6.23E7 -3.19 3.0197562E7 -6.08E7 -3.28 -4.5746 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G10 positive control 3.0642963E7 -6.21E7 -3.18 3.2186215E7 -5.89E7 -3.17 -4.4929 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G11 positive control 3.0739087E7 -6.2E7 -3.18 3.1311385E7 -5.97E7 -3.22 -4.5227 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G12 positive control 3.0319035E7 -6.25E7 -3.2 3.0767367E7 -6.03E7 -3.25 -4.5587 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G13 mock treatment 7.9608861E7 -1.32E7 -0.67 8.4840768E7 -6210000.0 -0.33 -0.7133 -0.9475 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G14 mock treatment 7.7156566E7 -1.56E7 -0.8 7.8671551E7 -1.24E7 -0.67 -1.0371 -0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G15 mock treatment 8.1030379E7 -1.17E7 -0.6 8.10523E7 -9990000.0 -0.54 -0.8061 -0.9985 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G16 mock treatment 8.5257809E7 -7510000.0 -0.39 8.3515937E7 -7530000.0 -0.41 -0.5591 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G17 mock treatment 8.5869349E7 -6900000.0 -0.35 8.4408181E7 -6640000.0 -0.36 -0.5029 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G18 mock treatment 8.8460293E7 -4310000.0 -0.22 8.579315E7 -5250000.0 -0.28 -0.3563 -0.9925 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G19 mock treatment 8.8061104E7 -4710000.0 -0.24 8.9624042E7 -1420000.0 -0.08 -0.2249 -0.8879 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G20 mock treatment 8.9204516E7 -3570000.0 -0.18 9.3383097E7 2340000.0 0.13 -0.0403 -0.1816 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G21 mock treatment 1.01310019E8 8540000.0 0.44 9.5323309E7 4280000.0 0.23 0.4723 0.955 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G22 mock treatment 9.9461618E7 6690000.0 0.34 1.07456249E8 1.64E7 0.88 0.8673 0.915 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G23 mock treatment 9.7844042E7 5070000.0 0.26 1.03544193E8 1.25E7 0.67 0.6597 0.9144 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon G24 mock treatment 1.17001336E8 2.42E7 1.24 1.02306995E8 1.13E7 0.61 1.3069 0.9457 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H01 positive control 3.2708511E7 -6.01E7 -3.08 3.2252123E7 -5.88E7 -3.17 -4.4155 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H02 positive control 3.1051084E7 -6.17E7 -3.16 3.0754375E7 -6.03E7 -3.25 -4.5326 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H03 positive control 3.1013141E7 -6.18E7 -3.17 3.150905E7 -5.95E7 -3.21 -4.5053 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H04 positive control 3.1631716E7 -6.11E7 -3.13 3.1165918E7 -5.99E7 -3.22 -4.4959 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H05 positive control 3.0756779E7 -6.2E7 -3.18 3.1938213E7 -5.91E7 -3.18 -4.4982 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H06 positive control 3.0854332E7 -6.19E7 -3.17 3.1074972E7 -6.0E7 -3.23 -4.5276 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H07 positive control 3.1221096E7 -6.16E7 -3.15 3.1770035E7 -5.93E7 -3.19 -4.4878 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H08 positive control 3.035902E7 -6.24E7 -3.2 3.1125409E7 -5.99E7 -3.23 -4.5436 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H09 positive control 3.0147181E7 -6.26E7 -3.21 3.124549E7 -5.98E7 -3.22 -4.5467 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H10 positive control 3.0625773E7 -6.21E7 -3.19 3.0658716E7 -6.04E7 -3.25 -4.5517 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H11 positive control 3.0268492E7 -6.25E7 -3.2 3.1026005E7 -6.0E7 -3.23 -4.5507 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H12 positive control 3.0367128E7 -6.24E7 -3.2 3.0872337E7 -6.02E7 -3.24 -4.5529 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H13 mock treatment 7.6525684E7 -1.62E7 -0.83 7.9978778E7 -1.11E7 -0.6 -1.0102 -0.9866 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H14 mock treatment 8.0548769E7 -1.22E7 -0.63 8.5896157E7 -5150000.0 -0.28 -0.6391 -0.9328 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H15 mock treatment 8.4592556E7 -8180000.0 -0.42 8.0283464E7 -1.08E7 -0.58 -0.7063 -0.9873 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H16 mock treatment 8.2601438E7 -1.02E7 -0.52 8.2212657E7 -8830000.0 -0.48 -0.705 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H17 mock treatment 8.7856856E7 -4910000.0 -0.25 8.6299466E7 -4750000.0 -0.26 -0.3589 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H18 mock treatment 8.9774861E7 -3000000.0 -0.15 8.5065684E7 -5980000.0 -0.32 -0.3363 -0.9426 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H19 mock treatment 9.1962905E7 -808000.0 -0.04 9.0052293E7 -994000.0 -0.05 -0.0672 -0.9919 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H20 mock treatment 9.3730101E7 959000.0 0.05 9.091706E7 -130000.0 -0.01 0.0298 0.6006 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H21 mock treatment 9.5654181E7 2880000.0 0.15 9.6954214E7 5910000.0 0.32 0.3294 0.9392 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H22 mock treatment 1.01495545E8 8720000.0 0.45 1.02646119E8 1.16E7 0.62 0.7579 0.9866 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H23 mock treatment 1.05440768E8 1.27E7 0.65 1.09015866E8 1.8E7 0.97 1.1434 0.9812 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon H24 mock treatment 1.17629302E8 2.49E7 1.27 1.14227275E8 2.32E7 1.25 1.7836 0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I01 positive control 3.3863411E7 -5.89E7 -3.02 3.3537576E7 -5.75E7 -3.1 -4.3247 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I02 positive control 3.1247973E7 -6.15E7 -3.15 3.1906506E7 -5.91E7 -3.18 -4.4816 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I03 positive control 3.1301455E7 -6.15E7 -3.15 3.1724669E7 -5.93E7 -3.19 -4.4866 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I04 positive control 3.1225165E7 -6.15E7 -3.15 3.1535767E7 -5.95E7 -3.2 -4.4966 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I05 positive control 3.104265E7 -6.17E7 -3.16 3.0868272E7 -6.02E7 -3.24 -4.5286 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I06 positive control 3.100947E7 -6.18E7 -3.17 3.0932681E7 -6.01E7 -3.24 -4.5274 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I07 positive control 3.2024892E7 -6.07E7 -3.11 3.2444713E7 -5.86E7 -3.16 -4.433 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I08 positive control 3.0445891E7 -6.23E7 -3.19 3.0805905E7 -6.02E7 -3.24 -4.5526 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I09 positive control 3.1573043E7 -6.12E7 -3.14 2.9901482E7 -6.11E7 -3.29 -4.5462 -0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I10 positive control 2.9631669E7 -6.31E7 -3.24 3.0720002E7 -6.03E7 -3.25 -4.5854 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I11 positive control 3.0631338E7 -6.21E7 -3.18 3.18213E7 -5.92E7 -3.19 -4.5072 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I12 positive control 3.0764787E7 -6.2E7 -3.18 3.1674195E7 -5.94E7 -3.2 -4.508 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I13 mock treatment 7.8138772E7 -1.46E7 -0.75 8.2447652E7 -8600000.0 -0.46 -0.8577 -0.9732 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I14 mock treatment 8.1214427E7 -1.16E7 -0.59 8.3500965E7 -7550000.0 -0.41 -0.7062 -0.9831 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I15 mock treatment 8.8961746E7 -3810000.0 -0.2 8.7476024E7 -3570000.0 -0.19 -0.274 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I16 mock treatment 8.3691802E7 -9080000.0 -0.47 8.1447962E7 -9600000.0 -0.52 -0.6946 -0.9986 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I17 mock treatment 8.7226051E7 -5550000.0 -0.28 8.599513E7 -5050000.0 -0.27 -0.3933 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I18 mock treatment 9.1321312E7 -1450000.0 -0.07 9.1328576E7 282000.0 0.02 -0.0418 -0.5513 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I19 mock treatment 9.5760527E7 2990000.0 0.15 9.4361267E7 3310000.0 0.18 0.2345 0.9971 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I20 mock treatment 9.9053228E7 6280000.0 0.32 9.7313765E7 6270000.0 0.34 0.4663 0.9997 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I21 mock treatment 9.7078542E7 4310000.0 0.22 9.4047263E7 3000000.0 0.16 0.2704 0.9882 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I22 mock treatment 9.9887817E7 7120000.0 0.36 1.01578309E8 1.05E7 0.57 0.6589 0.9772 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I23 mock treatment 1.05441869E8 1.27E7 0.65 9.9569882E7 8520000.0 0.46 0.7837 0.9856 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon I24 mock treatment 1.17092477E8 2.43E7 1.25 1.11566072E8 2.05E7 1.1 1.6628 0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J01 positive control 3.391716E7 -5.89E7 -3.02 3.2920282E7 -5.81E7 -3.13 -4.3463 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J02 positive control 3.0746975E7 -6.2E7 -3.18 3.1511173E7 -5.95E7 -3.21 -4.5148 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J03 positive control 3.0097332E7 -6.27E7 -3.21 3.0861592E7 -6.02E7 -3.24 -4.5631 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J04 positive control 3.0148792E7 -6.26E7 -3.21 3.201022E7 -5.9E7 -3.18 -4.5175 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J05 positive control 3.0563541E7 -6.22E7 -3.19 3.0948483E7 -6.01E7 -3.24 -4.5429 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J06 positive control 3.0624999E7 -6.21E7 -3.19 3.1017098E7 -6.0E7 -3.23 -4.5381 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J07 positive control 3.0827012E7 -6.19E7 -3.17 3.0593505E7 -6.05E7 -3.26 -4.5469 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J08 positive control 3.0204945E7 -6.26E7 -3.21 3.0176875E7 -6.09E7 -3.28 -4.5853 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J09 positive control 2.9654902E7 -6.31E7 -3.23 3.0892212E7 -6.02E7 -3.24 -4.578 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J10 positive control 3.0192297E7 -6.26E7 -3.21 3.1340794E7 -5.97E7 -3.22 -4.5414 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J11 positive control 3.0833258E7 -6.19E7 -3.17 3.1342728E7 -5.97E7 -3.22 -4.5181 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J12 positive control 3.0293015E7 -6.25E7 -3.2 3.0889369E7 -6.02E7 -3.24 -4.555 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J13 mock treatment 7.8545725E7 -1.42E7 -0.73 8.3167015E7 -7880000.0 -0.42 -0.8156 -0.9668 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J14 mock treatment 8.3439718E7 -9330000.0 -0.48 8.3642333E7 -7400000.0 -0.4 -0.6201 -0.9959 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J15 mock treatment 8.4165683E7 -8610000.0 -0.44 8.6126901E7 -4920000.0 -0.26 -0.4992 -0.9703 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J16 mock treatment 8.535199E7 -7420000.0 -0.38 8.217234E7 -8870000.0 -0.48 -0.6068 -0.9936 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J17 mock treatment 5.3807834E7 -3.9E7 -2.0 4.9222202E7 -4.18E7 -2.25 -3.0047 -0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J18 mock treatment 8.9266013E7 -3510000.0 -0.18 8.8001852E7 -3040000.0 -0.16 -0.243 -0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J19 mock treatment 9.3587457E7 816000.0 0.04 9.117718E7 130000.0 0.01 0.0345 0.8144 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J20 mock treatment 9.9780565E7 7010000.0 0.36 9.7107589E7 6060000.0 0.33 0.4848 0.9989 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J21 mock treatment 9.7595972E7 4820000.0 0.25 9.4835345E7 3790000.0 0.2 0.3191 0.9954 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J22 mock treatment 9.8705281E7 5930000.0 0.3 1.01452992E8 1.04E7 0.56 0.6113 0.9588 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J23 mock treatment 1.11536425E8 1.88E7 0.96 1.0796842E8 1.69E7 0.91 1.3244 0.9996 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon J24 mock treatment 1.22149961E8 2.94E7 1.51 1.11751172E8 2.07E7 1.11 1.8531 0.9891 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K01 positive control 3.3471905E7 -5.93E7 -3.04 3.3121214E7 -5.79E7 -3.12 -4.3548 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K02 positive control 3.1390654E7 -6.14E7 -3.15 3.2195948E7 -5.89E7 -3.17 -4.4654 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K03 positive control 3.026842E7 -6.25E7 -3.2 3.1513948E7 -5.95E7 -3.21 -4.5321 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K04 positive control 3.0314441E7 -6.25E7 -3.2 3.0977251E7 -6.01E7 -3.23 -4.5508 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K05 positive control 3.1055518E7 -6.17E7 -3.16 3.0813658E7 -6.02E7 -3.24 -4.5302 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K06 positive control 3.0193804E7 -6.26E7 -3.21 3.1037986E7 -6.0E7 -3.23 -4.5529 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K07 positive control 3.0282708E7 -6.25E7 -3.2 3.1330492E7 -5.97E7 -3.22 -4.5385 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K08 positive control 3.0371127E7 -6.24E7 -3.2 3.0480423E7 -6.06E7 -3.26 -4.5677 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K09 positive control 3.1958683E7 -6.08E7 -3.12 3.1298229E7 -5.97E7 -3.22 -4.479 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K10 positive control 2.9742681E7 -6.3E7 -3.23 3.1159605E7 -5.99E7 -3.22 -4.5646 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K11 positive control 3.1250114E7 -6.15E7 -3.15 3.2104576E7 -5.89E7 -3.17 -4.474 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K12 positive control 3.0040861E7 -6.27E7 -3.22 3.0308E7 -6.07E7 -3.27 -4.5862 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K13 mock treatment 8.4266764E7 -8500000.0 -0.44 8.2411339E7 -8640000.0 -0.47 -0.637 -0.9995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K14 mock treatment 8.4113379E7 -8660000.0 -0.44 8.3632491E7 -7410000.0 -0.4 -0.5961 -0.9986 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K15 mock treatment 8.4961239E7 -7810000.0 -0.4 8.4207931E7 -6840000.0 -0.37 -0.5435 -0.9991 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K16 mock treatment 8.2761246E7 -1.0E7 -0.51 8.9488945E7 -1560000.0 -0.08 -0.4221 -0.8119 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K17 mock treatment 9.0111252E7 -2660000.0 -0.14 8.8837128E7 -2210000.0 -0.12 -0.1805 -0.9977 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K18 mock treatment 9.0349149E7 -2420000.0 -0.12 8.7577687E7 -3470000.0 -0.19 -0.2199 -0.9803 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K19 mock treatment 9.0834092E7 -1940000.0 -0.1 9.2442339E7 1400000.0 0.08 -0.0171 -0.137 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K20 mock treatment 9.8016903E7 5250000.0 0.27 9.9883829E7 8840000.0 0.48 0.5266 0.9635 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K21 mock treatment 9.3488134E7 717000.0 0.04 9.6146617E7 5100000.0 0.27 0.2202 0.7946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K22 mock treatment 9.9870084E7 7100000.0 0.36 1.01133356E8 1.01E7 0.54 0.6414 0.981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K23 mock treatment 9.8325726E7 5550000.0 0.28 9.6248366E7 5200000.0 0.28 0.3994 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon K24 mock treatment 1.11888586E8 1.91E7 0.98 1.05123224E8 1.41E7 0.76 1.2288 0.992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L01 positive control 3.3213643E7 -5.96E7 -3.05 3.2249995E7 -5.88E7 -3.17 -4.3973 -0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L02 positive control 3.0813891E7 -6.2E7 -3.18 3.1179001E7 -5.99E7 -3.22 -4.5251 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L03 positive control 3.2453934E7 -6.03E7 -3.09 3.2709656E7 -5.83E7 -3.14 -4.4073 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L04 positive control 3.0855781E7 -6.19E7 -3.17 3.0909618E7 -6.01E7 -3.24 -4.5338 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L05 positive control 3.0089452E7 -6.27E7 -3.21 3.0629561E7 -6.04E7 -3.25 -4.5722 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L06 positive control 3.0338917E7 -6.24E7 -3.2 3.1042465E7 -6.0E7 -3.23 -4.5475 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L07 positive control 2.940227E7 -6.34E7 -3.25 3.0251515E7 -6.08E7 -3.27 -4.6115 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L08 positive control 2.9639263E7 -6.31E7 -3.24 3.0002304E7 -6.1E7 -3.29 -4.6124 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L09 positive control 3.0350911E7 -6.24E7 -3.2 3.0206882E7 -6.08E7 -3.28 -4.5789 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L10 positive control 3.0034841E7 -6.27E7 -3.22 3.1479684E7 -5.96E7 -3.21 -4.5418 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L11 positive control 2.9565159E7 -6.32E7 -3.24 3.0376216E7 -6.07E7 -3.27 -4.6009 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L12 positive control 3.0498519E7 -6.23E7 -3.19 3.0737359E7 -6.03E7 -3.25 -4.5533 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L13 mock treatment 8.2829536E7 -9940000.0 -0.51 8.7077422E7 -3970000.0 -0.21 -0.5114 -0.9256 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L14 mock treatment 8.1831871E7 -1.09E7 -0.56 8.537616E7 -5670000.0 -0.31 -0.6124 -0.9592 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L15 mock treatment 8.7313848E7 -5460000.0 -0.28 8.8021155E7 -3030000.0 -0.16 -0.313 -0.9669 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L16 mock treatment 8.4000521E7 -8770000.0 -0.45 8.5768042E7 -5280000.0 -0.28 -0.5189 -0.9756 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L17 mock treatment 8.8961855E7 -3810000.0 -0.2 9.2940014E7 1890000.0 0.1 -0.066 -0.2995 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L18 mock treatment 8.9141328E7 -3630000.0 -0.19 9.234372E7 1300000.0 0.07 -0.0822 -0.4135 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L19 mock treatment 9.0764003E7 -2010000.0 -0.1 9.5715736E7 4670000.0 0.25 0.105 0.3867 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L20 mock treatment 1.02173214E8 9400000.0 0.48 9.9924955E7 8880000.0 0.48 0.6788 1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L21 mock treatment 9.6050611E7 3280000.0 0.17 9.5530471E7 4480000.0 0.24 0.2896 0.9843 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L22 mock treatment 1.01942887E8 9170000.0 0.47 9.8762542E7 7720000.0 0.42 0.6262 0.9981 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L23 mock treatment 1.00230371E8 7460000.0 0.38 1.02930109E8 1.19E7 0.64 0.7228 0.9697 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon L24 mock treatment 1.1347717E8 2.07E7 1.06 1.04855999E8 1.38E7 0.74 1.2762 0.9849 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M01 positive control 3.764171E7 -5.51E7 -2.83 3.743125E7 -5.36E7 -2.89 -4.0395 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M02 positive control 3.2400358E7 -6.04E7 -3.09 3.2387333E7 -5.87E7 -3.16 -4.4216 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M03 positive control 3.0135436E7 -6.26E7 -3.21 3.1022493E7 -6.0E7 -3.23 -4.5556 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M04 positive control 3.0489105E7 -6.23E7 -3.19 3.1174859E7 -5.99E7 -3.22 -4.537 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M05 positive control 3.079939E7 -6.2E7 -3.18 3.2388803E7 -5.87E7 -3.16 -4.4795 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M06 positive control 3.1335583E7 -6.14E7 -3.15 3.1742984E7 -5.93E7 -3.19 -4.4847 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M07 positive control 3.0164393E7 -6.26E7 -3.21 3.0925465E7 -6.01E7 -3.24 -4.5583 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M08 positive control 3.1849877E7 -6.09E7 -3.12 3.1767028E7 -5.93E7 -3.19 -4.4651 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M09 positive control 3.0025165E7 -6.27E7 -3.22 3.0880497E7 -6.02E7 -3.24 -4.565 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M10 positive control 2.9873546E7 -6.29E7 -3.22 3.0877971E7 -6.02E7 -3.24 -4.5706 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M11 positive control 2.9958107E7 -6.28E7 -3.22 3.0763875E7 -6.03E7 -3.25 -4.5719 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M12 positive control 3.0796467E7 -6.2E7 -3.18 3.1385689E7 -5.97E7 -3.21 -4.5178 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M13 mock treatment 8.4354351E7 -8420000.0 -0.43 8.5156315E7 -5890000.0 -0.32 -0.5293 -0.9886 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M14 mock treatment 8.6058361E7 -6710000.0 -0.34 8.8704363E7 -2340000.0 -0.13 -0.3325 -0.9073 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M15 mock treatment 8.3789988E7 -8980000.0 -0.46 8.4727951E7 -6320000.0 -0.34 -0.5661 -0.9889 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M16 mock treatment 8.8379605E7 -4390000.0 -0.23 8.9171044E7 -1880000.0 -0.1 -0.2306 -0.9346 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M17 mock treatment 9.1249826E7 -1520000.0 -0.08 8.9340377E7 -1710000.0 -0.09 -0.1201 -0.9967 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M18 mock treatment 9.0060058E7 -2710000.0 -0.14 8.9748911E7 -1300000.0 -0.07 -0.1477 -0.9494 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M19 mock treatment 9.2641988E7 -129000.0 -0.01 9.1093693E7 46900.0 0.0 -0.0029 -0.4086 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M20 mock treatment 9.4490463E7 1720000.0 0.09 9.3167304E7 2120000.0 0.11 0.1431 0.9918 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M21 mock treatment 1.04555407E8 1.18E7 0.6 1.0404017E8 1.3E7 0.7 0.9218 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M22 mock treatment 9.8466605E7 5700000.0 0.29 9.5726559E7 4680000.0 0.25 0.3846 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M23 mock treatment 1.02236741E8 9470000.0 0.49 1.01480148E8 1.04E7 0.56 0.7403 0.9973 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon M24 mock treatment 1.08578283E8 1.58E7 0.81 1.02354874E8 1.13E7 0.61 1.0035 0.9901 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N01 positive control 3.3154163E7 -5.96E7 -3.06 3.3755673E7 -5.73E7 -3.09 -4.3421 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N02 positive control 3.4436624E7 -5.83E7 -2.99 3.4413445E7 -5.66E7 -3.05 -4.2706 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N03 positive control 2.9744397E7 -6.3E7 -3.23 3.1055951E7 -6.0E7 -3.23 -4.5685 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N04 positive control 3.0049341E7 -6.27E7 -3.21 3.1396446E7 -5.97E7 -3.21 -4.5445 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N05 positive control 3.0181144E7 -6.26E7 -3.21 3.0762372E7 -6.03E7 -3.25 -4.5639 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N06 positive control 2.967414E7 -6.31E7 -3.23 3.0494233E7 -6.06E7 -3.26 -4.5924 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N07 positive control 3.0176657E7 -6.26E7 -3.21 3.1271743E7 -5.98E7 -3.22 -4.5446 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N08 positive control 3.0100891E7 -6.27E7 -3.21 3.1363243E7 -5.97E7 -3.21 -4.5439 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N09 positive control 2.9969461E7 -6.28E7 -3.22 3.0309777E7 -6.07E7 -3.27 -4.5888 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N10 positive control 3.0166953E7 -6.26E7 -3.21 3.0269066E7 -6.08E7 -3.27 -4.5832 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N11 positive control 3.0170786E7 -6.26E7 -3.21 3.0366079E7 -6.07E7 -3.27 -4.5793 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N12 positive control 3.0439317E7 -6.23E7 -3.19 3.1224467E7 -5.98E7 -3.22 -4.5369 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N13 mock treatment 8.7145862E7 -5630000.0 -0.29 8.630509E7 -4740000.0 -0.26 -0.3844 -0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N14 mock treatment 8.6407971E7 -6360000.0 -0.33 9.4766498E7 3720000.0 0.2 -0.089 -0.2325 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N15 mock treatment 8.657897E7 -6190000.0 -0.32 8.793196E7 -3110000.0 -0.17 -0.343 -0.9556 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N16 mock treatment 8.6887663E7 -5880000.0 -0.3 8.9046728E7 -2000000.0 -0.11 -0.2894 -0.9038 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N17 mock treatment 8.8848905E7 -3920000.0 -0.2 9.3838889E7 2790000.0 0.15 -0.0358 -0.1427 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N18 mock treatment 9.2046473E7 -725000.0 -0.04 9.3438042E7 2390000.0 0.13 0.0648 0.4834 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N19 mock treatment 9.0083845E7 -2690000.0 -0.14 9.9696516E7 8650000.0 0.47 0.232 0.4776 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N20 mock treatment 1.04901186E8 1.21E7 0.62 1.03660332E8 1.26E7 0.68 0.9199 0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N21 mock treatment 9.4905263E7 2130000.0 0.11 9.5893813E7 4850000.0 0.26 0.2619 0.9254 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N22 mock treatment 9.6409065E7 3640000.0 0.19 9.708085E7 6030000.0 0.32 0.3616 0.9652 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N23 mock treatment 9.9290397E7 6520000.0 0.33 9.8800615E7 7750000.0 0.42 0.5315 0.9939 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon N24 mock treatment 1.11590896E8 1.88E7 0.96 1.07615873E8 1.66E7 0.89 1.313 0.9992 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O01 positive control 3.4410271E7 -5.84E7 -2.99 3.5071298E7 -5.6E7 -3.01 -4.2465 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O02 positive control 3.1842749E7 -6.09E7 -3.12 3.226533E7 -5.88E7 -3.17 -4.4464 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O03 positive control 3.1405026E7 -6.14E7 -3.15 3.19736E7 -5.91E7 -3.18 -4.4734 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O04 positive control 3.0685445E7 -6.21E7 -3.18 3.2374224E7 -5.87E7 -3.16 -4.4842 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O05 positive control 3.0264429E7 -6.25E7 -3.2 3.1908286E7 -5.91E7 -3.18 -4.5172 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O06 positive control 3.0296064E7 -6.25E7 -3.2 3.1683688E7 -5.94E7 -3.2 -4.5246 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O07 positive control 2.9827754E7 -6.29E7 -3.23 3.1575502E7 -5.95E7 -3.2 -4.5457 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O08 positive control 3.0011405E7 -6.28E7 -3.22 3.1197541E7 -5.98E7 -3.22 -4.5534 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O09 positive control 2.9605718E7 -6.32E7 -3.24 3.0953686E7 -6.01E7 -3.24 -4.5774 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O10 positive control 3.0141411E7 -6.26E7 -3.21 3.136982E7 -5.97E7 -3.21 -4.5422 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O11 positive control 3.0107195E7 -6.27E7 -3.21 3.1100924E7 -5.99E7 -3.23 -4.5536 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O12 positive control 3.038411E7 -6.24E7 -3.2 3.079651E7 -6.03E7 -3.24 -4.5552 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O13 mock treatment 8.6485539E7 -6290000.0 -0.32 9.4653422E7 3610000.0 0.19 -0.0905 -0.2405 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O14 mock treatment 8.9302742E7 -3470000.0 -0.18 9.2114664E7 1070000.0 0.06 -0.085 -0.4551 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O15 mock treatment 8.902107E7 -3750000.0 -0.19 9.471286E7 3670000.0 0.2 0.0037 0.0134 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O16 mock treatment 8.8470068E7 -4300000.0 -0.22 8.530761E7 -5740000.0 -0.31 -0.3744 -0.9863 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O17 mock treatment 8.9435887E7 -3340000.0 -0.17 9.4746535E7 3700000.0 0.2 0.02 0.0762 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O18 mock treatment 9.1626045E7 -1150000.0 -0.06 8.9171872E7 -1870000.0 -0.1 -0.1129 -0.9667 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O19 mock treatment 9.563153E7 2860000.0 0.15 9.0063468E7 -983000.0 -0.05 0.0662 0.4248 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O20 mock treatment 9.703286E7 4260000.0 0.22 9.3001688E7 1950000.0 0.11 0.2289 0.944 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O21 mock treatment 1.11077335E8 1.83E7 0.94 1.12427596E8 2.14E7 1.15 1.4776 0.9948 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O22 mock treatment 1.00575681E8 7800000.0 0.4 9.6280559E7 5230000.0 0.28 0.4821 0.9853 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O23 mock treatment 1.01554921E8 8780000.0 0.45 9.9735971E7 8690000.0 0.47 0.6492 0.9998 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon O24 mock treatment 1.14434831E8 2.17E7 1.11 1.14321993E8 2.33E7 1.25 1.6714 0.9982 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P01 positive control 3.5326616E7 -5.74E7 -2.94 3.4766852E7 -5.63E7 -3.03 -4.2249 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P02 positive control 3.2875335E7 -5.99E7 -3.07 3.3256979E7 -5.78E7 -3.11 -4.3712 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P03 positive control 3.3039814E7 -5.97E7 -3.06 3.3311217E7 -5.77E7 -3.11 -4.3632 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P04 positive control 3.1598661E7 -6.12E7 -3.14 3.1642891E7 -5.94E7 -3.2 -4.479 -0.9999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P05 positive control 3.168424E7 -6.11E7 -3.13 3.201863E7 -5.9E7 -3.18 -4.4615 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P06 positive control 3.1403748E7 -6.14E7 -3.15 3.3605819E7 -5.74E7 -3.09 -4.4113 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P07 positive control 3.0947269E7 -6.18E7 -3.17 3.2967932E7 -5.81E7 -3.13 -4.4521 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P08 positive control 3.1147149E7 -6.16E7 -3.16 3.1375097E7 -5.97E7 -3.21 -4.5055 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P09 positive control 3.0646456E7 -6.21E7 -3.18 3.2560377E7 -5.85E7 -3.15 -4.4785 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P10 positive control 3.097502E7 -6.18E7 -3.17 3.2623287E7 -5.84E7 -3.15 -4.4642 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P11 positive control 3.1078419E7 -6.17E7 -3.16 3.3098639E7 -5.79E7 -3.12 -4.4424 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P12 positive control 3.1773435E7 -6.1E7 -3.13 3.2077049E7 -5.9E7 -3.18 -4.4561 -1.0 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P13 mock treatment 9.8377844E7 5610000.0 0.29 9.5672012E7 4630000.0 0.25 0.3793 0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P14 mock treatment 9.170516E7 -1070000.0 -0.05 9.2508623E7 1460000.0 0.08 0.017 0.1777 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P15 mock treatment 9.2275441E7 -496000.0 -0.03 9.1745987E7 699000.0 0.04 0.0087 0.1906 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P16 mock treatment 9.2842711E7 71500.0 0.0 9.3992846E7 2950000.0 0.16 0.1148 0.7233 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P17 mock treatment 9.8980063E7 6210000.0 0.32 9.645332E7 5410000.0 0.29 0.4309 0.999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P18 mock treatment 9.8551364E7 5780000.0 0.3 9.7386009E7 6340000.0 0.34 0.4509 0.9975 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P19 mock treatment 1.00962995E8 8190000.0 0.42 9.6024297E7 4980000.0 0.27 0.4864 0.9765 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P20 mock treatment 1.00560445E8 7790000.0 0.4 1.00188993E8 9140000.0 0.49 0.6304 0.9946 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P21 mock treatment 1.12253475E8 1.95E7 1.0 9.7485251E7 6440000.0 0.35 0.9512 0.8999 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P22 mock treatment 1.07483307E8 1.47E7 0.75 9.9245278E7 8200000.0 0.44 0.8454 0.9675 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P23 mock treatment 1.16661919E8 2.39E7 1.22 1.07991599E8 1.69E7 0.91 1.5111 0.9895 1111.0003 CellTiterBlue(1111.0003) GSISyntheticLethal 1111.0003.PosCon P24 mock treatment 1.2521136E8 3.24E7 1.66 1.18342315E8 2.73E7 1.47 2.215 0.9981