ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A01 mock treatment 224280.0 59500.0 1.59 230520.0 66500.0 1.8 2.3983 0.9981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A02 mock treatment 233560.0 68800.0 1.84 228280.0 64200.0 1.74 2.5309 0.9996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A03 compound treatment 57880.0 -107000.0 -2.86 50240.0 -114000.0 -3.08 -4.2002 -0.9993 3076292 SMP2_000001 C[C@H](CCCC(C)(C)O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A04 compound treatment 214600.0 49900.0 1.33 215120.0 51100.0 1.38 1.9204 0.9998 170 SMP2_000002 CCCCCCCC[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A05 compound treatment 232440.0 67700.0 1.81 232240.0 68200.0 1.85 2.5855 1.0 3076293 SMP2_000003 CN(C)CC/C=C/1\c2ccccc2CC(O)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A06 compound treatment 120520.0 -44200.0 -1.18 37280.0 -127000.0 -3.43 -3.2635 -0.8989 2153 SMP2_000004 C[C@@H]1[C@@H](OC(=O)/C=C/C=C/c2ccccc2)[C@@]3(OC4(O[C@@H]3[C@@H]5[C@@H]6O[C@]6(CO)[C@@H](O)[C@@]7(O)[C@@H](C=C(C)C7=O)[C@@]15O4)c8ccccc8)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A07 compound treatment 227920.0 63200.0 1.69 233880.0 69800.0 1.89 2.5314 0.9984 3471112 SMP2_000005 CCOC(=O)CCC(=O)OC1C(CC(C)OC1OC2C(C)C(OC3CC(C)(OC)C(O)C(C)O3)C(C)C(=O)OC(CC)C(C)(O)C(O)C(C)C(=O)C(C)CC2(C)O)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A08 compound treatment 213280.0 48500.0 1.3 204160.0 40100.0 1.09 1.6856 0.996 2199 SMP2_000006 CC(C(C)c1ccc(O)cn1)C(N)C(=O)NC([C@H]2O[C@H]([C@@H](O)[C@H]2O)N3C=CC(=O)CC3=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A09 compound treatment 196560.0 31800.0 0.85 182120.0 18100.0 0.49 0.9474 0.9654 698 SMP2_000007 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A10 compound treatment 21520.0 -143000.0 -3.83 13720.0 -150000.0 -4.07 -5.587 -0.9995 3199281 SMP2_000008 CC(=C[C@@H](O)C1=C[C@@H](O)[C@@H]2O[C@@H]2C1=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A11 compound treatment 211560.0 46800.0 1.25 210840.0 46800.0 1.27 1.7809 1.0 1001979 SMP2_000009 NCCC[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A12 compound treatment 223280.0 58500.0 1.57 240200.0 76100.0 2.06 2.5646 0.9908 3199282 SMP2_000010 C[C@@H]1[C@@H](OC(=O)C)[C@]2(OC(=O)C)[C@H]([C@@H]3C=C(CO)C[C@]4(O)[C@@H](C=C(C)C4=O)[C@]13O)C2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A13 compound treatment 215680.0 50900.0 1.36 214080.0 50000.0 1.35 1.9209 1.0 1497 SMP2_000011 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)C2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A14 compound treatment 244280.0 79500.0 2.13 231080.0 67000.0 1.81 2.7873 0.9969 1000212 SMP2_000012 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A15 compound treatment 218720.0 54000.0 1.44 226760.0 62700.0 1.7 2.2211 0.9968 3199283 SMP2_000013 COC1/C=C\OC2(C)Oc3c(C2=O)c4c(O)cc(NC(=O)\C(=C/C=C\C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)\C)c(O)c4c(O)c3C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A16 compound treatment 16960.0 -148000.0 -3.95 15720.0 -148000.0 -4.02 -5.635 -1.0 2267 SMP2_000014 CO[C@H]1[C@H](O)C(O)[C@@H](OC1CO)n2c3c(Cl)cccc3c4c5C(=O)NC(=O)c5c6c7cccc(Cl)c7[nH]c6c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A17 compound treatment 221880.0 57100.0 1.53 236040.0 72000.0 1.95 2.4585 0.9928 706 SMP2_000015 Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A18 compound treatment 19280.0 -145000.0 -3.89 14600.0 -149000.0 -4.05 -5.6126 -0.9998 1098997 SMP2_000016 CCC1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A19 compound treatment 218960.0 54200.0 1.45 224640.0 60600.0 1.64 2.1851 0.9981 1001956 SMP2_000017 CC(C)C1N(C)c2cccc3[nH]cc(CC(CO)NC1=O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A20 compound treatment 253920.0 89200.0 2.39 246520.0 82500.0 2.23 3.2652 0.9995 1912779 SMP2_000018 CC(NC(=O)c1ccccc1/N=C/c2c(O)ccc3ccccc23)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A21 compound treatment 275520.0 111000.0 2.96 262760.0 98700.0 2.67 3.9846 0.9987 230 SMP2_000019 CCCCCC(=O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A22 compound treatment 10480.0 -154000.0 -4.13 9040.0 -155000.0 -4.2 -5.8854 -1.0 464 SMP2_000020 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A23 compound treatment 300280.0 136000.0 3.63 279440.0 115000.0 3.12 4.7722 0.9972 548 SMP2_000021 N[C@H]1C[C@H]([C@H](O)[C@@H]1O)n2cc(I)c3c(N)ncnc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 A24 compound treatment 219920.0 55200.0 1.48 217320.0 53300.0 1.44 2.0631 0.9999 3199284 SMP2_000022 C/C(=C/CNc1ncnc2[nH]cnc12)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B01 mock treatment 228480.0 63700.0 1.7 228080.0 64000.0 1.73 2.431 1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B02 mock treatment 188520.0 23800.0 0.64 214440.0 50400.0 1.36 1.4141 0.9397 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B03 compound treatment 180520.0 15800.0 0.42 161880.0 -2180.0 -0.06 0.2566 0.6023 1001866 SMP2_000023 NC(CCCNC(=N)N)C(=O)CC(Cc1ccccc1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B04 compound treatment 14280.0 -150000.0 -4.02 11560.0 -153000.0 -4.13 -5.7653 -0.9999 3076299 SMP2_000024 C[C@@H]1CCOC(=O)/C=C\C=C/C(=O)O[C@@H]2C[C@@H]3OC4C=C(C)CCC4(COC(=O)[C@H]1O)[C@]2(C)[C@@]53CO5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B05 compound treatment 135280.0 -29500.0 -0.79 125520.0 -38500.0 -1.04 -1.2951 -0.9904 3199377 SMP2_000025 CO[C@@H]1C[C@H](C)O[C@@H](CC[C@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)/C(=C/C[C@H](O)C[C@H]3O[C@@H](CC=C3)C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@H](C)[C@H](OC(=O)/C(=C/C[C@H](O)C[C@H]4O[C@@H](CC=C4)C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@@H]2C)/C)[C@@H](C)[C@@H](O)[C@@H](C)CC[C@@H]5C[C@@H](C[C@H](C)O5)OC)/C)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B06 compound treatment 170520.0 5770.0 0.15 142960.0 -21100.0 -0.57 -0.2947 -0.4981 3076300 SMP2_000026 CC1(C)C(O)C2(C)CCC1C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B07 compound treatment 186680.0 21900.0 0.59 150400.0 -13700.0 -0.37 0.1533 0.2211 3199378 SMP2_000027 CC(CO)C1CC(O)C2(C)OC3CC4OC5CC6(C)OC7CCC8OC9CC%10(C)OC%11C(CC%10OC9CC(C)C8OC7CC6OC5(C)CC=CC4OC3CC2O1)OC(=O)C=C%11C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B08 compound treatment 173400.0 8650.0 0.23 153600.0 -10500.0 -0.28 -0.0366 -0.1 3076301 SMP2_000028 Cn1cc(C[C@@H](N)C(=O)O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B09 compound treatment 11320.0 -153000.0 -4.1 8840.0 -155000.0 -4.2 -5.8734 -0.9999 28 SMP2_000029 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B10 compound treatment 10040.0 -155000.0 -4.14 8680.0 -155000.0 -4.21 -5.9006 -1.0 3199379 SMP2_000030 CC(C)CC(CO)NC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(CC(C)C)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B11 compound treatment 157400.0 -7350.0 -0.2 161000.0 -3060.0 -0.08 -0.1976 -0.9263 2006 SMP2_000031 O[C@H]1C2OC2[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B12 compound treatment 143000.0 -21700.0 -0.58 122080.0 -42000.0 -1.14 -1.215 -0.9516 3076303 SMP2_000032 CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B13 compound treatment 13320.0 -151000.0 -4.05 12040.0 -152000.0 -4.12 -5.7743 -1.0 3076304 SMP2_000033 CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C/2\C(=O)Nc3ccc(Cl)cc23)c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B14 compound treatment 181680.0 16900.0 0.45 165520.0 1460.0 0.04 0.3482 0.7659 1000114 SMP2_000034 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B15 compound treatment 160160.0 -4590.0 -0.12 161240.0 -2820.0 -0.08 -0.1408 -0.974 277 SMP2_000035 OC[C@H]1O[C@H]([C@H](O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B16 compound treatment 161520.0 -3230.0 -0.09 156280.0 -7780.0 -0.21 -0.21 -0.9224 3076306 SMP2_000036 CC(=O)c1ccc(cc1O)N2CCOCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B17 compound treatment 11800.0 -153000.0 -4.09 10000.0 -154000.0 -4.17 -5.8421 -1.0 2095622 SMP2_000037 CC(=CCC/C(=C/CC/C(=C/Cc1c(O)c2ccccc2oc1=O)/C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B18 compound treatment 176040.0 11300.0 0.3 171280.0 7220.0 0.2 0.3518 0.9778 1670 SMP2_000038 Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B19 compound treatment 53960.0 -111000.0 -2.96 18920.0 -145000.0 -3.93 -4.8739 -0.9903 2090 SMP2_000039 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B20 compound treatment 9640.0 -155000.0 -4.15 7880.0 -156000.0 -4.23 -5.9235 -1.0 1096696 SMP2_000040 Oc1ccc(cc1CC=C)c2cc(CC=C)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B21 compound treatment 233320.0 68600.0 1.83 230040.0 66000.0 1.79 2.5601 0.9999 3199380 SMP2_000041 NC1=NC(=O)/C(=C\2/CCNC(=O)c3[nH]c(Br)cc23)/N1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B22 compound treatment 64400.0 -100000.0 -2.68 75400.0 -88700.0 -2.4 -3.5952 -0.9984 2137 SMP2_000042 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B23 compound treatment 170840.0 6090.0 0.16 152040.0 -12000.0 -0.33 -0.1149 -0.3156 3104545 SMP2_000043 CC1CC(C)/C=C(/C)\CC(C)C(=O)NC(C)C(=O)N(C)C(Cc2c(Br)[nH]c3ccccc23)C(=O)NC(CC(=O)O1)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 B24 compound treatment 7920.0 -157000.0 -4.19 7480.0 -157000.0 -4.24 -5.9637 -1.0 907437 SMP2_000044 CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CCCCN 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C01 mock treatment 186840.0 22100.0 0.59 177200.0 13100.0 0.36 0.6694 0.9705 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C02 mock treatment 165120.0 373.0 0.01 156920.0 -7140.0 -0.19 -0.1296 -0.6697 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C03 compound treatment 106040.0 -58700.0 -1.57 97880.0 -66200.0 -1.79 -2.3773 -0.9978 907417 SMP2_000045 COc1cc2[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@@H]3CCc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C04 compound treatment 165920.0 1170.0 0.03 146520.0 -17500.0 -0.47 -0.3136 -0.6589 180 SMP2_000046 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(N)C(=O)NCC(=O)O)[C@@H](O)CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C05 compound treatment 12000.0 -153000.0 -4.09 10120.0 -154000.0 -4.17 -5.836 -1.0 3199382 SMP2_000047 C[C@@H]1CCC2[C@H](C[C@]3(C)C(=CCC4[C@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C06 compound treatment 11360.0 -153000.0 -4.1 9720.0 -154000.0 -4.18 -5.8558 -1.0 3104900 SMP2_000048 C/C(=C\CCC1C=CC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C07 compound treatment 47360.0 -117000.0 -3.14 19960.0 -144000.0 -3.9 -4.9788 -0.9942 907313 SMP2_000049 Oc1c(I)cc2c(Oc3c(I)c(O)c(I)cc3C42OC(=O)c5ccccc54)c1I 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C08 compound treatment 155000.0 -9750.0 -0.26 169800.0 5740.0 0.16 -0.0745 -0.2455 3076308 SMP2_000050 CCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C09 compound treatment 158640.0 -6110.0 -0.16 140200.0 -23900.0 -0.65 -0.5723 -0.8589 1002910 SMP2_000051 OC(C(O)C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C10 compound treatment 153120.0 -11600.0 -0.31 144440.0 -19600.0 -0.53 -0.5955 -0.9675 453 SMP2_000052 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C11 compound treatment 17560.0 -147000.0 -3.94 13280.0 -151000.0 -4.08 -5.6704 -0.9998 3199383 SMP2_000053 C[C@@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC[C@@]32C)[C@]45O[C@@H]5C[C@@H](C14)c6ccc(=O)oc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C12 compound treatment 168400.0 3650.0 0.1 153120.0 -10900.0 -0.3 -0.1404 -0.45 3199384 SMP2_000054 CC[C@H]1OC(=O)C[C@@H](O)C[C@@H](OC[C@]2(C)OC(C)[C@@H](O[C@@]3(C)C[C@@](C)(O)[C@@H](O)C(C)O3)[C@H](C2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C\C(=C/C1CO[C@@H]4OC(C)[C@@H](O)[C@H](OC)C4OC)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C13 compound treatment 179280.0 14500.0 0.39 150520.0 -13500.0 -0.37 0.0157 0.0293 3076309 SMP2_000055 C[C@]12CC[C@H](C3CCC(C)(C)OC3)[C@@]2(C)[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5[C@@H](O)C[C@]41C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C14 compound treatment 171000.0 6250.0 0.17 178240.0 14200.0 0.38 0.3897 0.9307 222 SMP2_000056 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C15 compound treatment 15120.0 -150000.0 -4.0 11600.0 -152000.0 -4.13 -5.7487 -0.9999 3076310 SMP2_000057 CC1(C)CC[C@H](F)[C@@]2(CO[C@@]3(O)[C@H](O)[C@H]12)[C@@H]4CC[C@@H]5[C@@H](O)[C@@]43C(=O)C5=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C16 compound treatment 156520.0 -8230.0 -0.22 144560.0 -19500.0 -0.53 -0.5289 -0.9247 3199385 SMP2_000058 OC[C@@H]1C[C@H](N[C@@H]2C=C(CO)[C@@H](O)[C@H](O)[C@H]2O)C(O)C(O)[C@@H]1O[C@@H]3OC(CO)[C@@H](O)[C@H](O)[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C17 compound treatment 153200.0 -11500.0 -0.31 146440.0 -17600.0 -0.48 -0.5557 -0.9779 1448 SMP2_000059 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C18 compound treatment 139360.0 -25400.0 -0.68 71560.0 -92500.0 -2.5 -2.2509 -0.8675 31 SMP2_000060 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C19 compound treatment 11520.0 -153000.0 -4.1 8840.0 -155000.0 -4.2 -5.8696 -0.9999 95 SMP2_000061 CCCCCC(O)/C=C/C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C20 compound treatment 9120.0 -156000.0 -4.16 7280.0 -157000.0 -4.24 -5.9449 -1.0 2065223 SMP2_000062 CN(C)c1ccc(cc1)C(O)(c2ccccc2)c3ccc(cc3)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C21 compound treatment 24640.0 -140000.0 -3.75 22040.0 -142000.0 -3.84 -5.3687 -0.9999 3199386 SMP2_000063 CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)/C(=C\C=C/[C@H](O)[C@@H](OC(=O)N)/C(=C\[C@H](C)[C@H]1O)/C)/C)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C22 compound treatment 174480.0 9730.0 0.26 163760.0 -301.0 -0.01 0.1783 0.6846 2041 SMP2_000064 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C23 compound treatment 177240.0 12500.0 0.33 184800.0 20700.0 0.56 0.6333 0.9693 3076311 SMP2_000065 COc1cc2ccnc3cc[nH]c(c1OC)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 C24 compound treatment 148640.0 -16100.0 -0.43 149720.0 -14300.0 -0.39 -0.5792 -0.9987 907566 SMP2_000066 C/C(=C\CNc1ncnc2n(cnc12)C3OC(CO)[C@@H](O)[C@H]3O)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D01 mock treatment 172960.0 8210.0 0.22 184920.0 20900.0 0.56 0.5546 0.9154 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D02 mock treatment 214280.0 49500.0 1.32 207760.0 43700.0 1.18 1.7734 0.9984 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D03 compound treatment 55160.0 -110000.0 -2.93 57080.0 -107000.0 -2.9 -4.1207 -1.0 3199387 SMP2_000067 CCC1/C=C(/C)\CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)C(O)CC1=O)/C(=C/C4CCC(O)C(C4)OC)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D04 compound treatment 297360.0 133000.0 3.55 264560.0 100000.0 2.72 4.4321 0.9914 907555 SMP2_000068 CC1=C[C@H]2O[C@@H]3C[C@@H](O)C(C)(C43CO4)[C@@]2(CO)CC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D05 compound treatment 200200.0 35500.0 0.95 198600.0 34500.0 0.94 1.3318 1.0 1962 SMP2_000069 CN(CC[C@H](N)CC(=O)N[C@H]1C=C[C@H](O[C@@H]1C(=O)O)n2ccc(N)nc2=O)C(=N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D06 compound treatment 199160.0 34400.0 0.92 199560.0 35500.0 0.96 1.3305 0.9998 852250 SMP2_000070 C1CCC(NC1)c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D07 compound treatment 161200.0 -3550.0 -0.09 171760.0 7700.0 0.21 0.0803 0.3506 3076314 SMP2_000071 O[C@@H]1C=CC(Br)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D08 compound treatment 133680.0 -31100.0 -0.83 155280.0 -8780.0 -0.24 -0.7557 -0.8743 3076315 SMP2_000072 OC[C@H]1O[C@H](C[C@@H]1O)n2cc(I)c(O)nc2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D09 compound treatment 83600.0 -81100.0 -2.17 54480.0 -110000.0 -2.97 -3.6326 -0.9882 3199389 SMP2_000073 CCCCCCCc1c(C)c(O)cc2c3ccccc3[nH]c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D10 compound treatment 171840.0 7090.0 0.19 197120.0 33100.0 0.89 0.767 0.8384 3199390 SMP2_000074 COc1ccc(cc1)C(O)(C2CC2)c3cncnc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D11 compound treatment 12240.0 -153000.0 -4.08 11920.0 -152000.0 -4.12 -5.797 -1.0 832324 SMP2_000075 COc1cc(OC)c2c(=O)c(C)c(CC[C@@H](C)[C@@H](C)[C@@H](C)[C@@H](C)/C=C/C=C/C(=C/C)/C)oc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D12 compound treatment 177000.0 12300.0 0.33 212280.0 48200.0 1.31 1.1548 0.858 2085117 SMP2_000076 COc1ccc(OC)c2c(=S)c3ccccc3[nH]c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D13 compound treatment 183200.0 18500.0 0.49 172360.0 8300.0 0.22 0.5079 0.9365 251 SMP2_000077 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D14 compound treatment 14040.0 -151000.0 -4.03 11040.0 -153000.0 -4.14 -5.7798 -0.9999 2007 SMP2_000078 CO[C@@H]1[C@@H](OC(=O)c2ccc(C)[nH]2)[C@@H](O)[C@H](CC1(C)C)Oc3ccc4CC(NC(=O)c5[nH]cc(CC(=O)Nc6cc7ccc(O[C@@H]8OC(C)(C)[C@H](OC)[C@@H](OC(=O)c9ccc(C)[nH]9)[C@H]8O)c(C)c7oc6=O)c5C)C(=O)Oc4c3C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D15 compound treatment 181200.0 16500.0 0.44 166560.0 2500.0 0.07 0.359 0.8063 751 SMP2_000079 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D16 compound treatment 132920.0 -31800.0 -0.85 113360.0 -50700.0 -1.37 -1.5726 -0.9736 3076316 SMP2_000080 Oc1cc(ccc1C(=O)c2ccccc2)N3CCOCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D17 compound treatment 188000.0 23300.0 0.62 185440.0 21400.0 0.58 0.8491 0.9994 3076317 SMP2_000081 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@H](C[C@H](C[C@@H](C)C\C(=C/[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC)[C@H](C[C@H]4C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D18 compound treatment 190320.0 25600.0 0.68 166240.0 2180.0 0.06 0.5254 0.7652 1392 SMP2_000082 CNC(C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D19 compound treatment 228000.0 63300.0 1.69 202160.0 38100.0 1.03 1.9257 0.9718 610 SMP2_000083 O=S(=O)(N1CCCNCC1)c2cccc3cnccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D20 compound treatment 178080.0 13300.0 0.36 152760.0 -11300.0 -0.31 0.0358 0.0763 3076318 SMP2_000084 Oc1nccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D21 compound treatment 140240.0 -24500.0 -0.66 78440.0 -85600.0 -2.32 -2.1026 -0.8728 616 SMP2_000085 COc1cc(O)c2c(=O)c(OC)c3CC(C)C(C(=O)C)c4c(OC)c(=O)c5c(O)cc(OC)c6c1c2c3c4c56 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D22 compound treatment 137680.0 -27100.0 -0.72 47840.0 -116000.0 -3.15 -2.7368 -0.8477 1096695 SMP2_000086 Oc1ccc(CC=C)cc1c2cc(CC=C)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D23 compound treatment 170880.0 6130.0 0.16 191320.0 27300.0 0.74 0.6378 0.8437 3176136 SMP2_000087 C[C@@H]1C2NCC(C)C[C@H]2O[C@@]31CCC4C5CC=C6CC(O)CCC6(C)C5C(=O)C4=C3C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 D24 compound treatment 209320.0 44600.0 1.19 201480.0 37400.0 1.01 1.5594 0.9967 3076319 SMP2_000088 Nc1nc(OCC2CCCCC2)c3[nH]cnc3n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E01 mock treatment 148360.0 -16400.0 -0.44 166920.0 2860.0 0.08 -0.2552 -0.5734 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E02 mock treatment 166800.0 2050.0 0.05 152320.0 -11700.0 -0.32 -0.1859 -0.5764 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E03 compound treatment 162600.0 -2150.0 -0.06 174360.0 10300.0 0.28 0.1565 0.5499 445 SMP2_000089 NC(=O)c1cccc(N)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E04 compound treatment 43560.0 -121000.0 -3.24 44440.0 -120000.0 -3.24 -4.5821 -1.0 1057045 SMP2_000090 COC(=O)c1ccc(O)c2nc3c(C=O)c(O)cc(O)c3nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E05 compound treatment 203400.0 38700.0 1.03 191960.0 27900.0 0.76 1.2652 0.9881 1949 SMP2_000091 NOC(=O)C1=CC(=C(c2ccc(O)c(c2)C(=O)ON)c3ccc(O)c(c3)C(=O)ON)C=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E06 compound treatment 86640.0 -78100.0 -2.09 79880.0 -84200.0 -2.28 -3.0888 -0.9991 2180 SMP2_000092 COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C(C)C)c4n2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E07 compound treatment 38520.0 -126000.0 -3.38 43920.0 -120000.0 -3.25 -4.6874 -0.9998 1020463 SMP2_000093 Oc1cc2ccc(=O)oc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E08 compound treatment 162040.0 -2710.0 -0.07 144880.0 -19200.0 -0.52 -0.4184 -0.798 3076699 SMP2_000094 CN1CCC[C@H]1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E09 compound treatment 9760.0 -155000.0 -4.15 8960.0 -155000.0 -4.2 -5.9006 -1.0 1694 SMP2_000095 Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E10 compound treatment 39600.0 -125000.0 -3.35 37640.0 -126000.0 -3.42 -4.7872 -0.9999 2345 SMP2_000096 Nc1ncnc2n(ccc12)[C@@H]3O[C@H](CO)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E11 compound treatment 159200.0 -5550.0 -0.15 165040.0 979.0 0.03 -0.0862 -0.5718 3199487 SMP2_000097 C[C@@H]1CC[C@@]2(C[C@H](C)C3C(=CCC4[C@@]3(C)C[C@@H](O)C5[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]45C)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E12 compound treatment 145960.0 -18800.0 -0.5 167320.0 3260.0 0.09 -0.293 -0.5742 2240 SMP2_000098 CC(C)C[C@H](NP(=O)(O)OC1OC(C)C(O)C(O)C1O)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E13 compound treatment 152120.0 -12600.0 -0.34 154920.0 -9140.0 -0.25 -0.4138 -0.9883 1000145 SMP2_000099 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E14 compound treatment 17040.0 -148000.0 -3.95 13080.0 -151000.0 -4.09 -5.684 -0.9999 267 SMP2_000100 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E15 compound treatment 155080.0 -9670.0 -0.26 164920.0 859.0 0.02 -0.1664 -0.641 1114632 SMP2_000101 CC1OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)C(O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E16 compound treatment 185920.0 21200.0 0.57 137960.0 -26100.0 -0.71 -0.0992 -0.1095 1000121 SMP2_000102 C/C(=C\CO)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E17 compound treatment 192720.0 28000.0 0.75 166560.0 2500.0 0.07 0.5769 0.7679 1599897 SMP2_000103 O=c1n2CCc3c([nH]c4ccccc34)-c2nc5ccccc15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E18 compound treatment 166480.0 1730.0 0.05 154360.0 -9700.0 -0.26 -0.1529 -0.5734 2354 SMP2_000104 COc1ccc2C3C4[C@H](CC(C)(C)OO[C@H](C=C(C)C)N4c2c1)N5C(=O)[C@@H]6CCCN6C(=O)[C@]5(O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E19 compound treatment 163840.0 -907.0 -0.02 154240.0 -9820.0 -0.27 -0.2052 -0.7684 1001870 SMP2_000105 C/C(=C/C(=O)O)/C=C/[C@@]1(O)C(=CC(=O)CC1(C)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E20 compound treatment 167560.0 2810.0 0.08 149960.0 -14100.0 -0.38 -0.2167 -0.557 296 SMP2_000106 Nc1ncnc2N(=CNc21)C3CCCO3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E21 compound treatment 116760.0 -48000.0 -1.28 117560.0 -46500.0 -1.26 -1.7978 -1.0 600 SMP2_000107 COC(=O)/C=C/c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E22 compound treatment 13000.0 -152000.0 -4.06 10760.0 -153000.0 -4.15 -5.8048 -0.9999 2327 SMP2_000108 CCC(C)C1NC2C=Cc3c(cc(nc3C2O)C(=O)OC(C)C(NCC(=O)c4csc(n4)C(NC(=O)c5csc(n5)/C(=C\C)/NC(=O)C(NC(=O)c6csc(n6)C7(CCC(=NC7)c8nc(cs8)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)NC(=C)C(C)NC(=O)C(=C)NCC(C)NC1=O)C(C)O)C(C)(O)C(C)O)c9nccs9)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E23 compound treatment 8160.0 -157000.0 -4.19 7480.0 -157000.0 -4.24 -5.9592 -1.0 3076759 SMP2_000109 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](COP(=O)(O)OCC[N+](C)(C)C)NC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 E24 compound treatment 151280.0 -13500.0 -0.36 132760.0 -31300.0 -0.85 -0.8539 -0.9274 3199491 SMP2_000110 C/C=C/C1OC2=C(C(=O)C[C@H](C)O2)C(=O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F01 mock treatment 174920.0 10200.0 0.27 167520.0 3460.0 0.09 0.2586 0.8987 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F02 mock treatment 208000.0 43300.0 1.16 186680.0 22600.0 0.61 1.2511 0.9557 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F03 compound treatment 209200.0 44500.0 1.19 186680.0 22600.0 0.61 1.2738 0.9524 907179 SMP2_000111 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)C(O)CC1(C)C)/C=C/C=C(\C)/C=C/C2=C(C)C(=O)C(O)CC2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F04 compound treatment 19720.0 -145000.0 -3.88 14320.0 -150000.0 -4.05 -5.6096 -0.9998 3076760 SMP2_000112 COc1cc(O)c2c3oc4cc(O)c(O)cc4c3c(=O)oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F05 compound treatment 170880.0 6130.0 0.16 172440.0 8380.0 0.23 0.2764 0.9873 328 SMP2_000113 C/C=C(/C)\C=C\1/CN=C2N(CCC2(O)C1=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F06 compound treatment 164840.0 93.3 0.0 156680.0 -7380.0 -0.2 -0.1395 -0.6982 3076761 SMP2_000114 CNCC/C=C/1\c2ccccc2CC(O)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F07 compound treatment 129080.0 -35700.0 -0.95 135960.0 -28100.0 -0.76 -1.2126 -0.9937 3199493 SMP2_000115 CCC/C=C/C=C/C(=O)O[C@H]1\C(=C\C(=O)OC)\C[C@H]2C[C@@H](OC(=O)C[C@H](O)C[C@H]3C[C@H](OC(=O)C)C(C)(C)[C@](O)(C[C@@H]4C/C(=C/C(=O)OC)/C[C@@H](O4)/C=C\C(C)(C)[C@]1(O)O2)O3)[C@@H](C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F08 compound treatment 140480.0 -24300.0 -0.65 139520.0 -24500.0 -0.66 -0.9288 -0.9999 1046629 SMP2_000116 Nc1cc2c3ccccc3ccc2c4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F09 compound treatment 11360.0 -153000.0 -4.1 11360.0 -153000.0 -4.13 -5.8244 -1.0 1037664 SMP2_000117 CSCS(=O)CC(CO)NC(=O)C=Cc1c(C)nc(O)nc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F10 compound treatment 152040.0 -12700.0 -0.34 154320.0 -9740.0 -0.26 -0.4268 -0.9921 1943 SMP2_000118 CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@@]4(C)O[C@H](CO)[C@@H](N)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F11 compound treatment 178120.0 13400.0 0.36 157080.0 -6980.0 -0.19 0.1193 0.2949 3199494 SMP2_000119 CC[C@@H]1C[C@@]1(NC(=O)C2=C[C@H](CC)C[C@H]3[C@@H]2CCC3=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F12 compound treatment 11800.0 -153000.0 -4.09 12120.0 -152000.0 -4.11 -5.8015 -1.0 1320 SMP2_000120 C[C@]1(CC[C@]2(C)CC[C@]3(C)C4=CC=C5C=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F13 compound treatment 105080.0 -59700.0 -1.6 114080.0 -50000.0 -1.35 -2.0854 -0.9966 745 SMP2_000121 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F14 compound treatment 10800.0 -154000.0 -4.12 10280.0 -154000.0 -4.16 -5.8556 -1.0 2008 SMP2_000122 CC1=C(SCCO)C(=O)c2ccccc2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F15 compound treatment 124280.0 -40500.0 -1.08 135160.0 -28900.0 -0.78 -1.3187 -0.9873 3199495 SMP2_000123 CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)COP(=O)(O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F16 compound treatment 158000.0 -6750.0 -0.18 151560.0 -12500.0 -0.34 -0.3669 -0.9566 3076763 SMP2_000124 Oc1ccc2c(Oc3cc(O)ccc3C42OC(=O)c5ccc(Nc6nc(Cl)nc(Cl)n6)cc54)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F17 compound treatment 162200.0 -2550.0 -0.07 189600.0 25500.0 0.69 0.4407 0.6344 1433 SMP2_000125 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F18 compound treatment 145040.0 -19700.0 -0.53 135200.0 -28900.0 -0.78 -0.9252 -0.9816 1100216 SMP2_000126 CC(=CCCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC54C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F19 compound treatment 13080.0 -152000.0 -4.06 11480.0 -153000.0 -4.13 -5.7895 -1.0 3000453 SMP2_000127 C[C@@H]1CC2OC(=O)C(=C)C2[C@H](O)[C@@]3(C)[C@H]1C=CC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F20 compound treatment 150800.0 -13900.0 -0.37 153240.0 -10800.0 -0.29 -0.4709 -0.9928 3060680 SMP2_000128 Oc1ccccc1N2CC=C(NC2=O)c3cccc(c3)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F21 compound treatment 10160.0 -155000.0 -4.14 9440.0 -155000.0 -4.19 -5.8838 -1.0 1907753 SMP2_000129 CC[C@@H]1[C@H](C)C[C@@H]2[C@H]3C[C@H]4CCC(=O)C5=C(O)[C@H](CCCNC(=O)/C=C\C[C@@H]4[C@H]3C=C[C@@H]12)NC5=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F22 compound treatment 8360.0 -156000.0 -4.18 7960.0 -156000.0 -4.23 -5.9462 -1.0 1001972 SMP2_000130 CCCC[C@@H](C)/C=C(\C)/C=C(\C)/C(=O)NC1=C[C@@](O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)[C@@H]3O[C@@H]3C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F23 compound treatment 166160.0 1410.0 0.04 177720.0 13700.0 0.37 0.2882 0.7754 3076765 SMP2_000131 CO[C@H]1[C@@H](CC(=O)O[C@H](C)C/C=C\C=C/[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(=O)CC(C)C)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 F24 compound treatment 33840.0 -131000.0 -3.5 25000.0 -139000.0 -3.76 -5.1381 -0.9993 288 SMP2_000132 C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G01 mock treatment 136240.0 -28500.0 -0.76 155720.0 -8340.0 -0.23 -0.6989 -0.8788 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G02 mock treatment 147840.0 -16900.0 -0.45 148080.0 -16000.0 -0.43 -0.6257 -0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G03 compound treatment 141560.0 -23200.0 -0.62 146480.0 -17600.0 -0.48 -0.7751 -0.9915 2407 SMP2_000133 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ncc(C)s3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G04 compound treatment 166800.0 2050.0 0.05 142040.0 -22000.0 -0.6 -0.3827 -0.6393 907364 SMP2_000134 CCC(C(=O)NC/C=C\C=C(\C)/C(OC)C(C)C1OC(\C=C/C=C\C=C(\C)/C(=O)c2c(O)cc[nH]c2=O)C(O)C1O)C3(O)OC(\C=C/C=C\C)C(C)(C)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G05 compound treatment 144600.0 -20100.0 -0.54 160480.0 -3580.0 -0.1 -0.4496 -0.8211 1978 SMP2_000135 OC(=O)/C=C/c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G06 compound treatment 11760.0 -153000.0 -4.09 11000.0 -153000.0 -4.14 -5.8237 -1.0 3076766 SMP2_000136 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G07 compound treatment 134440.0 -30300.0 -0.81 141880.0 -22200.0 -0.6 -0.9978 -0.9891 1117 SMP2_000137 Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cnc2[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G08 compound treatment 153080.0 -11700.0 -0.31 139160.0 -24900.0 -0.67 -0.6974 -0.9387 313 SMP2_000138 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G09 compound treatment 136680.0 -28100.0 -0.75 153120.0 -10900.0 -0.3 -0.7403 -0.9173 3076819 SMP2_000139 COCC(=O)c1ncn-2c1[C@@H]3CCNC3C(=O)c4cc(OC)ccc42 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G10 compound treatment 126360.0 -38400.0 -1.03 146080.0 -18000.0 -0.49 -1.0703 -0.9419 3199591 SMP2_000140 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCCC)COC(=O)Cc5ccc(O)c(OC)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G11 compound treatment 131920.0 -32800.0 -0.88 135120.0 -28900.0 -0.78 -1.1749 -0.9984 939 SMP2_000141 Cc1cccc(Nc2ccccc2C(=O)O)c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G12 compound treatment 16800.0 -148000.0 -3.96 60760.0 -103000.0 -2.8 -4.7758 -0.9856 3076821 SMP2_000142 CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G13 compound treatment 132600.0 -32100.0 -0.86 144840.0 -19200.0 -0.52 -0.976 -0.9711 1012954 SMP2_000143 OC(Cc1ccncc1)C(Cl)(Cl)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G14 compound treatment 115520.0 -49200.0 -1.32 128680.0 -35400.0 -0.96 -1.6084 -0.9878 4637 SMP2_000144 C[C@@H]1C[C@]2(OC(=O)C)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G15 compound treatment 135240.0 -29500.0 -0.79 162520.0 -1540.0 -0.04 -0.5876 -0.7435 942 SMP2_000145 OC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G16 compound treatment 13480.0 -151000.0 -4.05 12440.0 -152000.0 -4.1 -5.7636 -1.0 3199592 SMP2_000146 CCCC[C@]1(CC[C@]2(CC[C@H](C)[C@@H](C/C=C(\C)/C=C/[C@H](O)[C@@H](C)/C=C/C(=O)O)O2)O[C@H]1\C=C\C(=C\C(=O)O)\C)OC(=O)CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G17 compound treatment 132720.0 -32000.0 -0.86 132680.0 -31400.0 -0.85 -1.2065 -1.0 1011013 SMP2_000147 Nc1ccc2nc3ccc(N)cc3[s+]c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G18 compound treatment 146040.0 -18700.0 -0.5 141280.0 -22800.0 -0.62 -0.7899 -0.9946 3076824 SMP2_000148 NC(=O)OCC1N=C(N)N2CCC(O)(O)C32NC(=NC13)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G19 compound treatment 165920.0 1170.0 0.03 152840.0 -11200.0 -0.3 -0.1926 -0.6307 3199593 SMP2_000149 COc1cc(ccc1O)[C@H]2Oc3cc(ccc3O[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G20 compound treatment 142960.0 -21800.0 -0.58 149000.0 -15100.0 -0.41 -0.7004 -0.9847 3185114 SMP2_000150 CC[C@]1(C=CCN2CC[C@]3([C@H]4N(C)c5cc(OC)ccc53)[C@@H]21)[C@@H](OC(=O)C)[C@]4(O)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G21 compound treatment 148480.0 -16300.0 -0.44 167240.0 3180.0 0.09 -0.2468 -0.5565 3199594 SMP2_000151 C[C@@H]1[C@@H](O)[C@]2(O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G22 compound treatment 144480.0 -20300.0 -0.54 149360.0 -14700.0 -0.4 -0.6648 -0.9885 3076825 SMP2_000152 NC(=O)C1CCCN1C(=O)C(Cc2c[nH]cn2)NC(=O)C3CCC(=O)N3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G23 compound treatment 49360.0 -115000.0 -3.09 51560.0 -113000.0 -3.05 -4.3361 -1.0 1095351 SMP2_000153 COC1=C(Br)C(O)C(O)(CC#N)C=C1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 G24 compound treatment 108320.0 -56400.0 -1.51 106600.0 -57500.0 -1.56 -2.1673 -0.9999 3 SMP2_000154 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H01 mock treatment 159480.0 -5270.0 -0.14 157360.0 -6700.0 -0.18 -0.2279 -0.9922 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H02 mock treatment 175880.0 11100.0 0.3 161640.0 -2420.0 -0.07 0.1642 0.5386 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H03 compound treatment 159320.0 -5430.0 -0.15 173640.0 9580.0 0.26 0.0807 0.2716 3199595 SMP2_000155 CCC(C)C(NC(=O)C1CC(=O)NCC(=O)NC(Cc2ccccc2)C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(Cc3c[nH]c4ccccc34)C(=O)NCC(=O)NC(CC(=O)N)C(=O)N1)C(=O)NC(Cc5ccccc5)C(=O)NCC(=O)NC(Cc6c[nH]cn6)C(=O)NC(Cc7ccc(O)cc7)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(Cc8ccccc8)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H04 compound treatment 9440.0 -155000.0 -4.15 9720.0 -154000.0 -4.18 -5.8921 -1.0 1303231 SMP2_000156 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H05 compound treatment 123760.0 -41000.0 -1.1 125640.0 -38400.0 -1.04 -1.5107 -0.9997 3076826 SMP2_000157 Nc1ccccc1NC(=O)CCCCCCC(=O)Nc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H06 compound treatment 138800.0 -25900.0 -0.69 134520.0 -29500.0 -0.8 -1.0563 -0.9975 3076827 SMP2_000158 OC[C@H]1CC2CCN1CC2C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H07 compound treatment 15160.0 -150000.0 -4.0 15520.0 -149000.0 -4.02 -5.6729 -1.0 3199596 SMP2_000159 OC(=O)c1cc(/C=C/c2ccc(/C=C/c3ccc(O)c(c3)C(=O)O)c(Br)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H08 compound treatment 67360.0 -97400.0 -2.6 72440.0 -91600.0 -2.48 -3.5959 -0.9997 1088673 SMP2_000160 CC(C)C1NC(=O)C(NC(=O)c2cc(N)c(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H09 compound treatment 137200.0 -27500.0 -0.74 150080.0 -14000.0 -0.38 -0.7887 -0.9521 3069011 SMP2_000161 NCCC(=O)NCCc1c[nH]cn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H10 compound treatment 141240.0 -23500.0 -0.63 159520.0 -4540.0 -0.12 -0.5315 -0.8297 1025 SMP2_000162 CC(C)CC(=O)OC1C(O[C@@H]2C[C@H]([C@H]3CC[C@]4(C[C@@H]5CC[C@H]4[C@]3(C)C2)[C@@H](O)C5=C)C(=O)O)OC(CO)C(OS(=O)(=O)O)C1OS(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H11 compound treatment 168280.0 3530.0 0.09 181240.0 17200.0 0.47 0.3957 0.8338 1018447 SMP2_000163 Oc1ccc2c(c1)oc3c2c(=O)oc4cc(O)ccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H12 compound treatment 150720.0 -14000.0 -0.38 161800.0 -2260.0 -0.06 -0.3086 -0.8117 1000068 SMP2_000164 CC1=C(N2[C@H](SC1)C(NC(=O)C(N)c3ccccc3)C2=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H13 compound treatment 63680.0 -101000.0 -2.7 71680.0 -92400.0 -2.5 -3.6801 -0.9992 526 SMP2_000165 C[C@@H](O)[C@@H]1O[C@H]1/C=C/[C@@H]2O[C@H]2[C@H](O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H14 compound treatment 72160.0 -92600.0 -2.48 61640.0 -102000.0 -2.77 -3.7119 -0.9984 460 SMP2_000166 CCC1NC(=O)C([C@H](O)[C@H](C)C/C=C/C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H15 compound treatment 159320.0 -5430.0 -0.15 147240.0 -16800.0 -0.46 -0.4247 -0.8885 907301 SMP2_000167 CCC(C)C(O)C(C)C(=O)C(C)/C=C(\C)/CC(C)C1OC(=O)C1CC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H16 compound treatment 142760.0 -22000.0 -0.59 156480.0 -7580.0 -0.21 -0.561 -0.9006 3076266 SMP2_000168 CO[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H17 compound treatment 142440.0 -22300.0 -0.6 174240.0 10200.0 0.28 -0.2271 -0.3455 1001938 SMP2_000169 COC[C@H]1CC[C@H]2[C@@H](C)[C@@H](O)[C@H](OC3OC(COC(C)(C)C=C)[C@H](O)C(OC(=O)C)[C@@H]3O)C4=C(CC(O)[C@]4(C)C=C12)C(C)COC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H18 compound treatment 12000.0 -153000.0 -4.09 11600.0 -152000.0 -4.13 -5.8077 -1.0 829 SMP2_000170 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H19 compound treatment 68240.0 -96500.0 -2.58 68320.0 -95700.0 -2.59 -3.6581 -1.0 2334 SMP2_000171 C/C(=C\1/C(=O)NC(Cc2ccccc2)C1=O)/Nc3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H20 compound treatment 139000.0 -25700.0 -0.69 141480.0 -22600.0 -0.61 -0.9193 -0.9982 2109 SMP2_000172 OCc1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H21 compound treatment 87600.0 -77100.0 -2.06 86160.0 -77900.0 -2.11 -2.9504 -0.9999 2106 SMP2_000173 COC1=CC(=O)C(=C(C[C@]2(C)[C@@H](C)CC[C@@]3(C)[C@H]2CCCC3=C)C1=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H22 compound treatment 140480.0 -24300.0 -0.65 130480.0 -33600.0 -0.91 -1.1018 -0.9864 1260 SMP2_000174 N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H23 compound treatment 53080.0 -112000.0 -2.99 30280.0 -134000.0 -3.62 -4.6731 -0.9954 3076270 SMP2_000175 C[C@]12C=Cc3occc3C2CC[C@]4(C[C@H]5CCC41)C[C@]5(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 H24 compound treatment 143520.0 -21200.0 -0.57 144160.0 -19900.0 -0.54 -0.7825 -0.9997 3199601 SMP2_000176 CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I01 mock treatment 147120.0 -17600.0 -0.47 153360.0 -10700.0 -0.29 -0.5383 -0.9727 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I02 mock treatment 164240.0 -507.0 -0.01 167880.0 3820.0 0.1 0.0635 0.6092 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I03 compound treatment 151720.0 -13000.0 -0.35 161000.0 -3060.0 -0.08 -0.305 -0.8515 3076271 SMP2_000177 OC(=O)/C=C/c1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I04 compound treatment 9800.0 -155000.0 -4.14 9640.0 -154000.0 -4.18 -5.8868 -1.0 3199602 SMP2_000178 C/C(=C\CCC1=CC(=O)OC1O)/CC/C=C(\C)/CCC2=C(C)CCCC2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I05 compound treatment 8080.0 -157000.0 -4.19 8640.0 -155000.0 -4.21 -5.9385 -1.0 1135 SMP2_000179 OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I06 compound treatment 154320.0 -10400.0 -0.28 156440.0 -7620.0 -0.21 -0.3431 -0.989 252 SMP2_000180 CCCCCCOC(=O)[C@]1(O)C[C@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I07 compound treatment 134760.0 -30000.0 -0.8 159040.0 -5020.0 -0.14 -0.6633 -0.8153 3076272 SMP2_000181 COC(=O)C1=CO[C@@H](O[C@@H]2OC(CO)[C@H](O)[C@@H](O)[C@H]2O)[C@H]3[C@@H]1CC=C3CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I08 compound treatment 147880.0 -16900.0 -0.45 161520.0 -2540.0 -0.07 -0.3677 -0.8056 3199603 SMP2_000182 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCCCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I09 compound treatment 142320.0 -22400.0 -0.6 161600.0 -2460.0 -0.07 -0.4713 -0.7808 2129 SMP2_000183 OCC(O)C1OC(=O)C(=C1O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I10 compound treatment 133320.0 -31400.0 -0.84 136600.0 -27500.0 -0.74 -1.1201 -0.9981 3199692 SMP2_000184 CCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCC)COC(=O)Cc5ccc(O)c(OC)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I11 compound treatment 51040.0 -114000.0 -3.04 51920.0 -112000.0 -3.04 -4.2974 -1.0 1865 SMP2_000185 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I12 mock treatment 148280.0 -16500.0 -0.44 156280.0 -7780.0 -0.21 -0.4604 -0.943 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I13 compound treatment 132920.0 -31800.0 -0.85 151960.0 -12100.0 -0.33 -0.8336 -0.9139 3472730 SMP2_000186 CC12CCC3C(CC=C4CC(O)CCC34C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I14 compound treatment 140320.0 -24400.0 -0.65 158880.0 -5180.0 -0.14 -0.5612 -0.8398 3076274 SMP2_000187 Oc1ccc(cc1)C2COc3cc(O)ccc3C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I15 compound treatment 10120.0 -155000.0 -4.14 10960.0 -153000.0 -4.14 -5.8555 -1.0 2288 SMP2_000188 CC(=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I16 compound treatment 56480.0 -108000.0 -2.9 58680.0 -105000.0 -2.85 -4.0651 -1.0 3199693 SMP2_000189 COC(C(C)C1CC(O)C2(C)OC2/C=C\C(C)C3CC(CC(=O)O3)CC4OC4C(=O)O1)C(=CC=CC(=Cc5coc(C)n5)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I17 compound treatment 153560.0 -11200.0 -0.3 177280.0 13200.0 0.36 0.0415 0.0889 1025605 SMP2_000190 OCCN(CCO)CCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I18 compound treatment 125040.0 -39700.0 -1.06 145240.0 -18800.0 -0.51 -1.1113 -0.9434 3060146 SMP2_000191 Oc1ccc(cc1)c2nc(c([nH]2)c3ccc(F)cc3)c4ccncc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I19 compound treatment 163200.0 -1550.0 -0.04 179600.0 15500.0 0.42 0.2682 0.6345 1874 SMP2_000192 Oc1cccc2c(O)nccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I20 compound treatment 124120.0 -40600.0 -1.09 131480.0 -32600.0 -0.88 -1.3921 -0.9946 1080610 SMP2_000193 COc1ccc(O)c2c(=O)c3c(OC)cc4OC5OC=CC5c4c3oc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I21 compound treatment 157960.0 -6790.0 -0.18 183440.0 19400.0 0.52 0.2426 0.437 2290 SMP2_000194 C[C@]1(CC(N)CCC(N)C(=O)O)O[C@](C)([C@@H](O)[C@H]1O)n2cnc3c(N)ncnc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I22 compound treatment 162520.0 -2230.0 -0.06 141280.0 -22800.0 -0.62 -0.4782 -0.7718 3076167 SMP2_000195 CC(C)C1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)/C=C(/C)\C=C/CNC(=O)\C=C/C1C)n3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I23 compound treatment 151480.0 -13300.0 -0.35 183840.0 19800.0 0.54 0.1277 0.1988 1077786 SMP2_000196 CC(C)CC1N2C(=O)C(NC(=O)C3CN(C)C4Cc5c[nH]c6cccc(C4=C3)c56)(OC2(O)C7CCCN7C1=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 I24 compound treatment 68040.0 -96700.0 -2.59 63360.0 -101000.0 -2.73 -3.7569 -0.9997 325 SMP2_000197 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J01 mock treatment 153520.0 -11200.0 -0.3 169920.0 5860.0 0.16 -0.1002 -0.295 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J02 mock treatment 152640.0 -12100.0 -0.32 166600.0 2540.0 0.07 -0.1804 -0.5449 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J03 compound treatment 153000.0 -11700.0 -0.31 164400.0 339.0 0.01 -0.2157 -0.6862 3076170 SMP2_000198 OC[C@@H]1[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J04 compound treatment 161680.0 -3070.0 -0.08 170200.0 6140.0 0.17 0.0595 0.3211 677 SMP2_000199 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J05 compound treatment 123320.0 -41400.0 -1.11 130040.0 -34000.0 -0.92 -1.4348 -0.9958 2060246 SMP2_000200 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C/C=C/3\[C@H](O)COC3=O)C(=C)CCC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J06 compound treatment 169000.0 4250.0 0.11 149120.0 -14900.0 -0.4 -0.2056 -0.4892 414 SMP2_000201 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J07 compound treatment 131520.0 -33200.0 -0.89 162080.0 -1980.0 -0.05 -0.6664 -0.7484 1972 SMP2_000202 COC(=O)/C(=C\Nc1ccc(Oc2ccccc2OC(C)C)nc1)/NC(=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J08 compound treatment 145120.0 -19600.0 -0.52 174760.0 10700.0 0.29 -0.1664 -0.2776 3189311 SMP2_000203 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](N)C2=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J09 compound treatment 9640.0 -155000.0 -4.15 12760.0 -151000.0 -4.1 -5.8301 -1.0 2109607 SMP2_000204 CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(=O)O)c2c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J10 compound treatment 53360.0 -111000.0 -2.98 89680.0 -74400.0 -2.01 -3.5307 -0.9818 1960 SMP2_000205 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J11 compound treatment 161280.0 -3470.0 -0.09 165400.0 1340.0 0.04 -0.0399 -0.4012 3199694 SMP2_000206 CC1[C@H]2NC[C@@H](C)C[C@H]2O[C@@]31CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J12 compound treatment 8720.0 -156000.0 -4.17 10440.0 -154000.0 -4.16 -5.8919 -1.0 874122 SMP2_000207 COc1c(O)c2c(=O)cc3OCOc4cc(O)c5c(=O)c(OC)c(CC(C)O)c6c(c1CC(C)O)c2c3c4c56 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J13 compound treatment 139400.0 -25300.0 -0.68 151880.0 -12200.0 -0.33 -0.7126 -0.9452 1301 SMP2_000208 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J14 compound treatment 109480.0 -55300.0 -1.48 123360.0 -40700.0 -1.1 -1.8245 -0.9895 1001900 SMP2_000209 Nc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J15 compound treatment 139600.0 -25100.0 -0.67 153320.0 -10700.0 -0.29 -0.6813 -0.9296 2056 SMP2_000210 CC(C)CC(NC(=O)NC(C1CCNC(=N1)N)C(=O)NC(CCC(=O)N)C(=O)NC(C)C=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J16 compound treatment 82960.0 -81800.0 -2.19 94760.0 -69300.0 -1.88 -2.8736 -0.9971 599 SMP2_000211 Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J17 compound treatment 181520.0 16800.0 0.45 184920.0 20900.0 0.56 0.7166 0.9935 162 SMP2_000212 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J18 compound treatment 137760.0 -27000.0 -0.72 147960.0 -16100.0 -0.44 -0.8187 -0.9708 3076285 SMP2_000213 CN1C(=O)/C(=C/2\Nc3ccccc3\C2=N\O)/c4ccc(Br)cc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J19 compound treatment 14080.0 -151000.0 -4.03 17080.0 -147000.0 -3.98 -5.6634 -1.0 3199695 SMP2_000214 CC1O[C@@H](O[C@H]2C[C@@H](C=O)C3C(CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)c6ccc(=O)oc6)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O[C@@H]7OC(CO)[C@@H](O)[C@@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J20 compound treatment 97640.0 -67100.0 -1.8 101360.0 -62700.0 -1.7 -2.4696 -0.9996 3076287 SMP2_000215 COc1cc(O)c(CC=C(C)C)c2OC(CC(=O)c12)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J21 compound treatment 148480.0 -16300.0 -0.44 153560.0 -10500.0 -0.28 -0.5087 -0.9787 2411 SMP2_000216 NCC1O[C@@H](O[C@@H]2[C@H](N)C[C@@H](N)C(O[C@H]3OC(CO)[C@@H](O)[C@@H](N)[C@H]3O)C2O)[C@H](N)C[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J22 compound treatment 155320.0 -9430.0 -0.25 150640.0 -13400.0 -0.36 -0.4352 -0.9841 3199697 SMP2_000217 CCC(=O)O[C@H]1C(C)O[C@](C)(C[C@]1(C)O)O[C@@H]2C(C)O[C@@H](CO[C@@H]3[C@@H](C)[C@@H](CC(=O)O[C@H](C)C/C=C\C=C/[C@H](O)[C@H](C)C[C@@H]3CC(=O)C)OC(=O)CC)[C@H](O)[C@@H]2N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J23 compound treatment 8520.0 -156000.0 -4.18 9280.0 -155000.0 -4.19 -5.9179 -1.0 3076290 SMP2_000218 C[C@@H]1[C@H](O)[C@@H](C)[C@H]2O[C@@H]1CC[C@H](C)/C=C(/C)\C[C@@H](C)C[C@H](C)[C@]3(O)OC4=C(C)C(=O)C(=C2C4=C3)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 J24 compound treatment 120280.0 -44500.0 -1.19 126800.0 -37300.0 -1.01 -1.5544 -0.9966 3199698 SMP2_000219 CC(NC(=O)C(NC(=O)c1nc(nc(N)c1C)C(CC(=O)N)NCC(N)C(=O)N)C(OC2OC(CO)C(O)C(O)C2(C)OC3OC(CO)C(O)C(O)(C3O)C(=O)N)c4cnc[nH]4)C(O)C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)c6nc(cs6)C(=O)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K01 mock treatment 138960.0 -25800.0 -0.69 159320.0 -4740.0 -0.13 -0.5785 -0.8245 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K02 mock treatment 172000.0 7250.0 0.19 161160.0 -2900.0 -0.08 0.0817 0.3901 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K03 compound treatment 43880.0 -121000.0 -3.23 50560.0 -114000.0 -3.07 -4.4589 -0.9997 3076443 SMP2_000220 CC(C)CCC[C@@H](C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K04 compound treatment 10160.0 -155000.0 -4.14 13040.0 -151000.0 -4.09 -5.8149 -1.0 25 SMP2_000221 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K05 compound treatment 119960.0 -44800.0 -1.2 136200.0 -27900.0 -0.75 -1.3805 -0.9751 3076448 SMP2_000222 CCC1=CC2C[C@@H]3c4[nH]c5ccccc5c4CCN(C2)[C@@]31C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K06 compound treatment 9000.0 -156000.0 -4.17 10200.0 -154000.0 -4.17 -5.8912 -1.0 309 SMP2_000223 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K07 compound treatment 7920.0 -157000.0 -4.19 9760.0 -154000.0 -4.18 -5.9201 -1.0 1000097 SMP2_000224 Cc1c(C)c2OC(C)(COc3ccc(CC4SC(=O)NC4=O)cc3)CCc2c(C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K08 compound treatment 54760.0 -110000.0 -2.94 89360.0 -74700.0 -2.02 -3.5103 -0.9833 2113458 SMP2_000225 CCC(=O)NCCc1c2scnc2c3nccc4c5ccccc5[nH]c1c43 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K09 compound treatment 78360.0 -86400.0 -2.31 149280.0 -14800.0 -0.4 -1.9169 -0.8174 3076491 SMP2_000226 CCCCCCCCCCCCCCCC(=O)OCC(O)[C@H]1OC(=O)C(=C1O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K10 compound treatment 147720.0 -17000.0 -0.46 173000.0 8940.0 0.24 -0.1509 -0.2927 3184 SMP2_000227 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O/C(=C\CCCC(=O)O)/C[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K11 compound treatment 24400.0 -140000.0 -3.75 29160.0 -135000.0 -3.65 -5.237 -0.9999 1313 SMP2_000228 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K12 compound treatment 140120.0 -24600.0 -0.66 151040.0 -13000.0 -0.35 -0.7151 -0.9571 3199699 SMP2_000229 CC(C)Nc1cccnc1N2CCN(CC2)C(=O)c3cc4cc(O)ccc4[nH]3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K13 compound treatment 139320.0 -25400.0 -0.68 158160.0 -5900.0 -0.16 -0.5939 -0.8501 2709 SMP2_000230 Cc1ncc(CO)c(CO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K14 compound treatment 34240.0 -131000.0 -3.49 53960.0 -110000.0 -2.98 -4.5761 -0.9969 3076498 SMP2_000231 CC1CC2OC2/C=C\C=C/C(=O)Cc3c(Cl)c(O)cc(O)c3C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K15 compound treatment 154280.0 -10500.0 -0.28 155240.0 -8820.0 -0.24 -0.3668 -0.9969 3076544 SMP2_000232 CCN(CC)CCCC(C)Nc1nc(C)cc(Nc2ccc3nc(C)cc(N)c3c2)n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K16 compound treatment 151440.0 -13300.0 -0.36 158960.0 -5100.0 -0.14 -0.3493 -0.915 633 SMP2_000233 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K17 compound treatment 11880.0 -153000.0 -4.09 22920.0 -141000.0 -3.82 -5.5932 -0.9994 3199700 SMP2_000234 CC1OC2OC3[C@@H](O)[C@@H](O)CO[C@H]3OC(=O)[C@@]45CCC(C)(C)C[C@H]5C6=CC[C@@H]7[C@@]8(C)C[C@H](O)[C@H](O[C@@H]9OC(CO)[C@@H](O)[C@H](O)C9O[C@@H]%10OC[C@@H](OC(=O)C[C@](C)(O)CC(=O)O[C@@H]1C(O[C@@H]%11OC[C@@H](O)[C@H](O)C%11O)[C@@H]2O)C(O)C%10O)[C@@](C)(CO)[C@@H]8CC[C@@]7(C)[C@]6(C)CC4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K18 compound treatment 140360.0 -24400.0 -0.65 135400.0 -28700.0 -0.78 -1.0099 -0.9963 3076548 SMP2_000235 NC1N=CC(=N1)[C@H]2[C@H](CNC(=O)c3cc(Br)c[nH]3)[C@@H](CNC(=O)c4cc(Br)c[nH]4)[C@@H]2C5=NC(N)N=C5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K19 compound treatment 140120.0 -24600.0 -0.66 165960.0 1900.0 0.05 -0.4294 -0.65 3076550 SMP2_000236 CCCCC[C@H](O)[C@H](SCC(N)C(=O)O)/C=C/C=C/C=C\C/C=C\CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K20 compound treatment 54880.0 -110000.0 -2.94 56760.0 -107000.0 -2.9 -4.1321 -1.0 3199701 SMP2_000237 CO[C@@H]1C[C@H](C)O[C@@H](CC[C@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)/C=C\C(=C/C[C@@H](O)C[C@@H]3CCC[C@@H](C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@H](C)[C@H](OC(=O)/C=C\C(=C/C[C@@H](O)C[C@@H]4CCC[C@@H](CC(OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@@H]2C)O4)\C)[C@@H](C)[C@@H](O)[C@@H](C)CC[C@H]5C[C@@H](C[C@H](C)O5)OC)O3)\C)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K21 compound treatment 25240.0 -140000.0 -3.73 17120.0 -147000.0 -3.98 -5.4516 -0.9995 3076553 SMP2_000238 CC(C)CCC[C@@H](C)[C@H]1C[C@H](O)C2=C3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K22 compound treatment 8000.0 -157000.0 -4.19 8800.0 -155000.0 -4.2 -5.9369 -1.0 2329 SMP2_000239 C[C@@H]1C[C@@]2(OC3(Cc4ccccc4)O[C@@H]2[C@@H]5C=C(COC(=O)Cc6ccc(O)cc6)C[C@@]7(O)[C@@H](C=C(C)C7=O)[C@@]15O3)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K23 compound treatment 136320.0 -28400.0 -0.76 125560.0 -38500.0 -1.04 -1.2747 -0.988 1000035 SMP2_000240 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 K24 compound treatment 168240.0 3490.0 0.09 165480.0 1420.0 0.04 0.0932 0.9228 1100080 SMP2_000241 OCC1OC(C(O)C1O)n2cccnc2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L01 mock treatment 155560.0 -9190.0 -0.25 144760.0 -19300.0 -0.52 -0.5432 -0.9408 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L02 mock treatment 182640.0 17900.0 0.48 150920.0 -13100.0 -0.36 0.0869 0.1457 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L03 compound treatment 165480.0 733.0 0.02 163120.0 -941.0 -0.03 -0.0041 -0.129 155 SMP2_000242 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L04 compound treatment 147960.0 -16800.0 -0.45 157680.0 -6380.0 -0.17 -0.4397 -0.9139 410 SMP2_000243 CC(=N)NCc1cccc(CN)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L05 compound treatment 140040.0 -24700.0 -0.66 145800.0 -18300.0 -0.49 -0.8169 -0.9898 1000029 SMP2_000244 CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]cn1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4)C(C)C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L06 compound treatment 175360.0 10600.0 0.28 166240.0 2180.0 0.06 0.2424 0.8362 3199703 SMP2_000245 CCC1OC2(C[C@@H]3CC(C/C=C(/C)\C(O[C@@H]4C[C@@H](C)C(O[C@H]5C[C@H](OC)C(O)[C@H](C)O5)[C@H](C4)OC)C(C)\C=C/C=C\6/COC7C6[C@@H](C=C(C)[C@H]7O)C(=O)O3)O2)C=CC1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L07 compound treatment 67640.0 -97100.0 -2.6 61760.0 -102000.0 -2.77 -3.7951 -0.9995 3076615 SMP2_000246 COC1/C=C\C=C(\C)/Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)CC(OC(=O)C(C)C)C3(C)OC3C(C)C4CC1(O)NC(=O)O4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L08 compound treatment 7160.0 -158000.0 -4.22 9600.0 -154000.0 -4.18 -5.9375 -1.0 3199793 SMP2_000247 CCN1C[C@]2(COC)CCC(OC)[C@]3(C4C[C@@]5(O)[C@H](OC(=O)c6ccc(OC)cc6)C4[C@](C[C@H]5OC)(OC(=O)C)[C@H]7[C@H](OC)C32)[C@@H]71 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L09 compound treatment 9080.0 -156000.0 -4.16 11280.0 -153000.0 -4.14 -5.869 -1.0 1983 SMP2_000248 CC(C)c1cc2C3CC4C(C)(C)CCCC4(C(=O)O3)c2c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L10 compound treatment 141440.0 -23300.0 -0.62 175840.0 11800.0 0.32 -0.2153 -0.3075 3199794 SMP2_000249 C[C@@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC[C@@]32C)[C@]45O[C@@H]5[C@H](OC(=O)C)[C@@H](C14)c6ccc(=O)oc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L11 compound treatment 50240.0 -115000.0 -3.06 52680.0 -111000.0 -3.02 -4.298 -1.0 3199795 SMP2_000250 CC1C2C(Cc3ccccc3)NC(=O)C24C(/C=C\CC(C)CC(C)(O)/C=C\C4O)C(O)C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L12 compound treatment 11680.0 -153000.0 -4.09 14800.0 -149000.0 -4.04 -5.7525 -1.0 964 SMP2_000251 CN(C)N=Nc1[nH]cnc1C(=O)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L13 compound treatment 10320.0 -154000.0 -4.13 11840.0 -152000.0 -4.12 -5.8349 -1.0 3076672 SMP2_000252 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)C(O)C2O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L14 compound treatment 160800.0 -3950.0 -0.11 161760.0 -2300.0 -0.06 -0.1187 -0.9684 1001931 SMP2_000253 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L15 compound treatment 121760.0 -43000.0 -1.15 144920.0 -19100.0 -0.52 -1.1795 -0.9352 831956 SMP2_000254 COc1c(O)ccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L16 compound treatment 123920.0 -40800.0 -1.09 127080.0 -37000.0 -1.0 -1.4801 -0.9991 604 SMP2_000255 Oc1c(Br)cc(/C=C\2/C3C=C(I)C=CC3NC2=O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L17 compound treatment 128640.0 -36100.0 -0.97 153400.0 -10700.0 -0.29 -0.887 -0.88 3199797 SMP2_000256 C[C@@]1([C@H]2[C@H](C(=O)O)[C@]3(CC4CC[C@H]3[C@@]52CC[C@@H]1O)CC4=C)C(=O)O5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L18 compound treatment 7440.0 -157000.0 -4.21 9920.0 -154000.0 -4.17 -5.9261 -1.0 604 SMP2_000257 Oc1c(Br)cc(/C=C\2/C3C=C(I)C=CC3NC2=O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L19 compound treatment 139120.0 -25600.0 -0.69 156040.0 -8020.0 -0.22 -0.6383 -0.8876 97 SMP2_000258 CCCCC/C=C\C[C@@H]1O[C@H]1\C=C\C(O)C/C=C\CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L20 compound treatment 135680.0 -29100.0 -0.78 140880.0 -23200.0 -0.63 -0.9935 -0.9944 3199798 SMP2_000259 CC1CC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L21 compound treatment 68520.0 -96200.0 -2.57 56960.0 -107000.0 -2.9 -3.8703 -0.9982 2108 SMP2_000260 COc1cc2C/C(=C\c3cc(C)c(O)c(C)c3)/C(=O)c2c(N)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L22 compound treatment 82280.0 -82500.0 -2.21 72560.0 -91500.0 -2.48 -3.3114 -0.9983 440 SMP2_000261 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L23 compound treatment 138320.0 -26400.0 -0.71 143160.0 -20900.0 -0.57 -0.9 -0.9939 1201 SMP2_000262 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 L24 compound treatment 74240.0 -90500.0 -2.42 85480.0 -78600.0 -2.13 -3.2162 -0.9979 648 SMP2_000263 Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M01 mock treatment 151920.0 -12800.0 -0.34 154760.0 -9300.0 -0.25 -0.4207 -0.9884 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M02 mock treatment 165680.0 933.0 0.02 163000.0 -1060.0 -0.03 -0.0027 -0.07 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M03 compound treatment 126040.0 -38700.0 -1.04 181760.0 17700.0 0.48 -0.3933 -0.3447 549 SMP2_000264 Nc1ncnc2nc(cc(c3cccc(Br)c3)c12)c4ccc(nc4)N5CCOCC5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M04 compound treatment 125920.0 -38800.0 -1.04 136840.0 -27200.0 -0.74 -1.2555 -0.9859 1092656 SMP2_000265 CC1OC(CC(=O)O)CC2=C1C(=O)c3c(O)cccc3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M05 compound treatment 133240.0 -31500.0 -0.84 138160.0 -25900.0 -0.7 -1.0918 -0.9958 1000067 SMP2_000266 NC(C(=O)NC1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M06 compound treatment 8800.0 -156000.0 -4.17 11080.0 -153000.0 -4.14 -5.8782 -1.0 535 SMP2_000267 ONC(=O)CCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M07 compound treatment 75720.0 -89000.0 -2.38 89240.0 -74800.0 -2.03 -3.1162 -0.9968 3177114 SMP2_000268 CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M08 compound treatment 128440.0 -36300.0 -0.97 143040.0 -21000.0 -0.57 -1.0891 -0.9676 241 SMP2_000269 CC[C@@H](C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NCC(N)CS 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M09 compound treatment 151320.0 -13400.0 -0.36 148360.0 -15700.0 -0.43 -0.5545 -0.9965 3076808 SMP2_000270 CC1(C)[C@H]2C[C@@H]1C(=C)[C@H](O)C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M10 compound treatment 137080.0 -27700.0 -0.74 155280.0 -8780.0 -0.24 -0.6914 -0.8895 220 SMP2_000271 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M11 compound treatment 9960.0 -155000.0 -4.14 12200.0 -152000.0 -4.11 -5.8348 -1.0 1579 SMP2_000272 CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M12 compound treatment 172400.0 7650.0 0.2 175360.0 11300.0 0.31 0.361 0.9809 284 SMP2_000273 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M13 compound treatment 156560.0 -8190.0 -0.22 149080.0 -15000.0 -0.41 -0.4416 -0.9582 3076815 SMP2_000274 CC(O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M14 compound treatment 134560.0 -30200.0 -0.81 160720.0 -3340.0 -0.09 -0.6349 -0.7814 1102317 SMP2_000275 COc1ccc(cc1)C23Oc4cc(OC)cc(OC)c4C3(O)C(O)C(C2c5ccccc5)C(=O)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M15 compound treatment 128200.0 -36500.0 -0.98 156000.0 -8060.0 -0.22 -0.8456 -0.8442 1907751 SMP2_000276 CN/C(=N\c1ccc(cc1)C2=NNC(=O)CC2C)/NC#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M16 compound treatment 59840.0 -105000.0 -2.81 53840.0 -110000.0 -2.98 -4.0942 -0.9995 536 SMP2_000277 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M17 compound treatment 6720.0 -158000.0 -4.23 9240.0 -155000.0 -4.19 -5.9527 -1.0 3076873 SMP2_000278 COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)/C=C/c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M18 compound treatment 6360.0 -158000.0 -4.24 8920.0 -155000.0 -4.2 -5.9657 -1.0 536 SMP2_000279 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M19 compound treatment 58320.0 -106000.0 -2.85 68320.0 -95700.0 -2.59 -3.8458 -0.9989 3199800 SMP2_000280 CC(C)CCC[C@@H](C)[C@H]1CC(=O)[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M20 compound treatment 132520.0 -32200.0 -0.86 179920.0 15900.0 0.43 -0.306 -0.3177 3199801 SMP2_000281 CO[C@@H]([C@H](O)CC(=O)[C@@H](C)[C@@H](O)CC[C@@H](C)C1O[C@]2(CC[C@@H](C)C(CC[C@H](C)C(=O)C)O2)CC[C@@H]1C)[C@H](OC(=O)C[C@@H](O)C3=C(C)C(=O)OC3=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M21 compound treatment 205800.0 41100.0 1.1 209840.0 45800.0 1.24 1.6528 0.9982 257 SMP2_000282 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M22 compound treatment 130760.0 -34000.0 -0.91 160960.0 -3100.0 -0.08 -0.7022 -0.7691 3076883 SMP2_000283 CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC1=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M23 compound treatment 161400.0 -3350.0 -0.09 154800.0 -9260.0 -0.25 -0.2406 -0.9037 2059 SMP2_000284 CC(C)CC(N)C(O)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 M24 compound treatment 17520.0 -147000.0 -3.94 28360.0 -136000.0 -3.67 -5.3824 -0.9994 2350 SMP2_000285 Cc1c(C)c2OC(C)(CN3CCN(CC3)c4cc(nc(n4)N5CCCC5)N6CCCC6)CCc2c(C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N01 mock treatment 164680.0 -66.7 0.0 157120.0 -6940.0 -0.19 -0.1341 -0.7138 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N02 mock treatment 161800.0 -2950.0 -0.08 166320.0 2260.0 0.06 -0.0125 -0.1253 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N03 compound treatment 177480.0 12700.0 0.34 171440.0 7380.0 0.2 0.3821 0.9677 3076955 SMP2_000286 CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)CC23C(=O)O[C@@H]4OC(=O)[C@H](O)C413 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N04 compound treatment 144440.0 -20300.0 -0.54 137360.0 -26700.0 -0.72 -0.8952 -0.9901 907302 SMP2_000287 CN1CC[C@]2(C)C1N(C)c3ccc(O)cc32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N05 compound treatment 146080.0 -18700.0 -0.5 189400.0 25300.0 0.69 0.132 0.1556 3199802 SMP2_000288 CSC(=S)NCc1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N06 compound treatment 149760.0 -15000.0 -0.4 163600.0 -461.0 -0.01 -0.2923 -0.7288 398 SMP2_000289 OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N07 compound treatment 9760.0 -155000.0 -4.15 13600.0 -150000.0 -4.07 -5.8118 -1.0 1975 SMP2_000290 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1c5ccc(=O)oc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N08 compound treatment 118560.0 -46200.0 -1.24 125120.0 -38900.0 -1.05 -1.619 -0.9969 1026746 SMP2_000291 OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N09 compound treatment 16840.0 -148000.0 -3.96 37600.0 -126000.0 -3.42 -5.2184 -0.9974 810 SMP2_000292 CCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N10 compound treatment 10040.0 -155000.0 -4.14 15920.0 -148000.0 -4.01 -5.7621 -0.9999 3176068 SMP2_000293 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N11 compound treatment 150360.0 -14400.0 -0.38 167280.0 3220.0 0.09 -0.2105 -0.5335 2018 SMP2_000294 NC1=NC(=O)/C(=C/2\CCNC(=O)c3[nH]ccc23)/N1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N12 compound treatment 144640.0 -20100.0 -0.54 170280.0 6220.0 0.17 -0.2613 -0.4636 1090 SMP2_000295 CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N13 compound treatment 130560.0 -34200.0 -0.91 151360.0 -12700.0 -0.34 -0.8898 -0.9107 3199804 SMP2_000296 CC(C)CC(NC(=O)C(Cc1ccc(OP(O)(O)O)cc1)NC(=O)C2CCCN2C(=O)C)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N14 compound treatment 7360.0 -157000.0 -4.21 10040.0 -154000.0 -4.17 -5.9253 -1.0 1000674 SMP2_000297 COc1cccc2C(=O)c3c(O)c4CC(O)(CC(OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N15 compound treatment 6040.0 -159000.0 -4.25 8920.0 -155000.0 -4.2 -5.9717 -1.0 1084811 SMP2_000298 Cc1c2[nH]c3ccc(O)cc3c2c(C)c4cnccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N16 compound treatment 14240.0 -151000.0 -4.03 139680.0 -24400.0 -0.66 -3.3135 -0.8122 3077040 SMP2_000299 CC(C)[C@H]1CN2CCC[C@H]2[C@@]3(O)O[C@](CC(=O)[C@H]4CN(C)[C@@H]5Cc6c[nH]c7cccc(C5=C4)c67)(C(C)C)C(=O)N13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N17 compound treatment 119400.0 -45300.0 -1.21 141640.0 -22400.0 -0.61 -1.2869 -0.9488 1108916 SMP2_000300 NCCCCC(NC(=O)C(Cc1c[nH]cn1)NC(=O)CN)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N18 compound treatment 9200.0 -156000.0 -4.16 16520.0 -148000.0 -3.99 -5.7665 -0.9998 3177114 SMP2_000301 CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N19 compound treatment 146280.0 -18500.0 -0.49 136840.0 -27200.0 -0.74 -0.8704 -0.9811 3076041 SMP2_000302 COc1cc(/C=C/c2cccc[n+]2C)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N20 compound treatment 141280.0 -23500.0 -0.63 148280.0 -15800.0 -0.43 -0.746 -0.9824 1734 SMP2_000303 Nc1nnc(c(N)n1)c2cccc(Cl)c2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N21 compound treatment 131280.0 -33500.0 -0.9 138080.0 -26000.0 -0.7 -1.1304 -0.9929 3076048 SMP2_000304 OC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N22 compound treatment 48600.0 -116000.0 -3.11 51720.0 -112000.0 -3.04 -4.3474 -0.9999 1000089 SMP2_000305 COC1C(C)OC(OC2CC(C)(O)C(C(=O)OC)c3cc4C(=O)c5c6OC7OC(C)(C(O)C(C7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)C(OC)C1(C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N23 compound treatment 123120.0 -41600.0 -1.11 115880.0 -48200.0 -1.3 -1.7097 -0.9969 628 SMP2_000306 Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 N24 compound treatment 179000.0 14300.0 0.38 130640.0 -33400.0 -0.9 -0.3702 -0.377 1273 SMP2_000307 C[C@@]12CC(=O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O01 mock treatment 150760.0 -14000.0 -0.37 166000.0 1940.0 0.05 -0.2274 -0.602 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O02 mock treatment 167040.0 2290.0 0.06 143600.0 -20500.0 -0.55 -0.3483 -0.625 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O03 compound treatment 137080.0 -27700.0 -0.74 161440.0 -2620.0 -0.07 -0.5735 -0.7714 1059696 SMP2_000308 CC1CCC2(C)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O04 compound treatment 153000.0 -11700.0 -0.31 178320.0 14300.0 0.39 0.0508 0.102 988 SMP2_000309 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O05 compound treatment 131120.0 -33600.0 -0.9 172440.0 8380.0 0.23 -0.4756 -0.5127 413 SMP2_000310 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O06 compound treatment 139360.0 -25400.0 -0.68 134200.0 -29900.0 -0.81 -1.0518 -0.9962 3199805 SMP2_000311 NC(=O)OC[C@H]1[C@@H]2NC(=N)N[C@]23N(CCC3(O)O)C(=N)N1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O07 compound treatment 86280.0 -78500.0 -2.1 80920.0 -83100.0 -2.25 -3.0757 -0.9994 2081802 SMP2_000312 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O08 compound treatment 117760.0 -47000.0 -1.26 139480.0 -24600.0 -0.67 -1.3593 -0.9558 1080649 SMP2_000313 CC1(CC2(O)OC3O1)C4(CC2C34COC(=O)c5ccccc5)OC6OC(CO)C(O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O09 compound treatment 104760.0 -60000.0 -1.6 94240.0 -69800.0 -1.89 -2.4712 -0.9967 3076119 SMP2_000314 CNc1ccc2ccccc2c1N=Nc3ccc(N=Nc4ccccc4)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O10 compound treatment 130200.0 -34500.0 -0.92 160560.0 -3500.0 -0.09 -0.7205 -0.7756 1072985 SMP2_000315 CC1C(O)C2(O)C(C3C=C(CO)CC4(O)C(C=C(C)C4=O)C13O)C2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O11 compound treatment 143840.0 -20900.0 -0.56 134160.0 -29900.0 -0.81 -0.9678 -0.9837 3076122 SMP2_000316 CC(=C[C@H](C=C)C(C)(C)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O12 compound treatment 81840.0 -82900.0 -2.22 92960.0 -71100.0 -1.92 -2.9292 -0.9975 3001166 SMP2_000317 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O13 compound treatment 8280.0 -156000.0 -4.19 9720.0 -154000.0 -4.18 -5.914 -1.0 189 SMP2_000318 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O14 compound treatment 118560.0 -46200.0 -1.24 130440.0 -33600.0 -0.91 -1.5172 -0.9887 3199895 SMP2_000319 CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)O)NC(=O)C3CCCN3C(=O)C(CC(=O)N)NC(=O)C4CCCN4C(=O)C(N)CCCCN)C(=O)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O15 compound treatment 6120.0 -159000.0 -4.24 8640.0 -155000.0 -4.21 -5.9756 -1.0 2305 SMP2_000320 COC1=C(N)C(=O)c2nc(ccc2C1=O)c3nc(C(=O)O)c(C)c(c3N)c4ccc(OC)c(OC)c4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O16 compound treatment 125360.0 -39400.0 -1.05 144000.0 -20100.0 -0.54 -1.129 -0.9525 3076126 SMP2_000321 Nc1ncnc2n([C@@H]3OC4COP(O)(S)O[C@@H]4C3O)c(nc12)N5CCCCC5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O17 compound treatment 81120.0 -83600.0 -2.24 75400.0 -88700.0 -2.4 -3.279 -0.9994 2080871 SMP2_000322 CC1=C(O)C(=O)[C@@H]2O[C@@H]2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O18 compound treatment 133800.0 -30900.0 -0.83 137960.0 -26100.0 -0.71 -1.085 -0.9969 3076175 SMP2_000323 COc1cc(ccc1O)[C@H]2Oc3cc(ccc3O[C@@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O19 compound treatment 10320.0 -154000.0 -4.13 9840.0 -154000.0 -4.18 -5.8731 -1.0 3199896 SMP2_000324 CC(C)CCC[C@@H](C)[C@H]1CC(=O)C2=C3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O20 compound treatment 135960.0 -28800.0 -0.77 140720.0 -23300.0 -0.63 -0.9913 -0.9952 3076177 SMP2_000325 COc1cc(ccc1O)c2cc(=O)c3c(O)cc(OC4OC(CO)C(O)C(O)C4OS(=O)(=O)O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O21 compound treatment 48640.0 -116000.0 -3.11 49320.0 -115000.0 -3.11 -4.3926 -1.0 2119025 SMP2_000326 Nc1nc(S)c2nc[nH]c2n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O22 compound treatment 11600.0 -153000.0 -4.1 14440.0 -150000.0 -4.05 -5.7609 -1.0 2081802 SMP2_000327 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O23 compound treatment 5840.0 -159000.0 -4.25 5960.0 -158000.0 -4.28 -6.0322 -1.0 316 SMP2_000328 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 O24 compound treatment 102440.0 -62300.0 -1.67 21240.0 -143000.0 -3.87 -3.9125 -0.9292 1004963 SMP2_000329 CC1CCC2(CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P01 mock treatment 167280.0 2530.0 0.07 162440.0 -1620.0 -0.04 0.0169 0.2091 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P02 mock treatment 153040.0 -11700.0 -0.31 140920.0 -23100.0 -0.63 -0.6644 -0.9486 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P03 compound treatment 156280.0 -8470.0 -0.23 177280.0 13200.0 0.36 0.0929 0.2194 3199897 SMP2_000330 CS[C@]12CC3=CC=CC(O)[C@H]3N2C(=O)[C@@](CO)(SC)N(C)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P04 compound treatment 135440.0 -29300.0 -0.78 142920.0 -21100.0 -0.57 -0.959 -0.9881 2060488 SMP2_000331 CC(=CCC[C@@](C)(O)C=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P05 compound treatment 144960.0 -19800.0 -0.53 153240.0 -10800.0 -0.29 -0.5814 -0.9611 1968 SMP2_000332 C[C@@H]1CC2OC3CC4OC(=O)C=C(C)C4O[C@@]3(C)CC2OC5CC[C@@]6(C)O[C@@]7(C)CC8OC9CC%10O[C@@]%11(C)[C@@H](O)C[C@@H](CC(=C)C=O)OC%11CC%10OC9C=CC[C@]8(C)OC7CC6OC15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P06 compound treatment 132040.0 -32700.0 -0.87 133720.0 -30300.0 -0.82 -1.1995 -0.9995 1000053 SMP2_000333 OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P07 compound treatment 45960.0 -119000.0 -3.18 81360.0 -82700.0 -2.24 -3.8299 -0.9853 1977 SMP2_000334 CC12CCc3occc3[C@H]2CCC4(CC5CC[C@H]41)C[C@]5(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P08 compound treatment 131320.0 -33400.0 -0.89 154320.0 -9740.0 -0.26 -0.8187 -0.8783 1693 SMP2_000335 NCCCNCCSP(=O)(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P09 compound treatment 12880.0 -152000.0 -4.06 100920.0 -63100.0 -1.71 -4.0812 -0.926 3199899 SMP2_000336 CC[C@@H]1[C@H](O)[C@@H](C)C/C(=C\C=C/C(=C(\OC(=O)\C(=C/C(=C\[C@H](C)C1O)/C)\OC)/[C@@H](C)[C@@H](O)[C@H](C)[C@@]2(O)C[C@@H](OC3CC(O)C(OC(=O)N)C(C)O3)[C@H](C)[C@H](O2)/C=C/C)/OC)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P10 compound treatment 94440.0 -70300.0 -1.88 119080.0 -45000.0 -1.22 -2.1909 -0.9779 446 SMP2_000337 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P11 compound treatment 108720.0 -56000.0 -1.5 126680.0 -37400.0 -1.01 -1.7753 -0.9817 360 SMP2_000338 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P12 compound treatment 52760.0 -112000.0 -3.0 87600.0 -76500.0 -2.07 -3.5819 -0.9837 3068886 SMP2_000339 CC(C)/N=c/1\cc2n(c3ccc(Cl)cc3)c4ccccc4nc2cc1Nc5ccc(Cl)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P13 compound treatment 86360.0 -78400.0 -2.1 88200.0 -75900.0 -2.05 -2.9349 -0.9999 1817 SMP2_000340 CC(=O)O[C@@]12CO[C@H]2C[C@@H](O)[C@@]3(C)[C@H]1[C@H](OC(=O)c4ccccc4)[C@@]5(O)C[C@H](OC(=O)[C@@H](O)[C@H](NC(=O)OC(C)(C)C)c6ccccc6)C(=C([C@H](O)C3=O)C5(C)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P14 compound treatment 132800.0 -31900.0 -0.85 152520.0 -11500.0 -0.31 -0.8252 -0.9069 3076236 SMP2_000341 COc1ccc(C=Cc2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P15 compound treatment 4880.0 -160000.0 -4.28 7040.0 -157000.0 -4.25 -6.0296 -1.0 832320 SMP2_000342 CC[C@H](C)[C@H](NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)C)C(=O)N[C@@H](C(=O)C)C(=O)N[C@@H](CC(C)C)[C@@]1(O)O[C@H](C)[C@H](N[C@@]1(C)CO)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P16 compound treatment 104840.0 -59900.0 -1.6 134280.0 -29800.0 -0.81 -1.7032 -0.9495 2069 SMP2_000343 CC12CCC3C(CCC4=C(O)C(=O)CCC34C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P17 compound treatment 121320.0 -43400.0 -1.16 137040.0 -27000.0 -0.73 -1.3387 -0.9752 3199902 SMP2_000344 CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(N)CO)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NC(Cc4ccccc4)C(=O)NCC(=O)NC(Cc5ccccc5)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P18 compound treatment 6040.0 -159000.0 -4.25 7160.0 -157000.0 -4.25 -6.0054 -1.0 2100 SMP2_000345 COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@H]2c3cc4OCOc4cc3CCN5CCC[C@]25C=C1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P19 compound treatment 108120.0 -56600.0 -1.51 129080.0 -35000.0 -0.95 -1.7407 -0.9744 613 SMP2_000346 Oc1cc(/C=C/c2ccc(O)c(O)c2)oc(=O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P20 compound treatment 124400.0 -40300.0 -1.08 131040.0 -33000.0 -0.89 -1.3953 -0.9956 3076242 SMP2_000347 CC1(C)O[C@H]2CC(=O)OC[C@]23[C@H]4CC[C@@](C)([C@@H](OC5OC(CO)C(O)C(O)C5O)c6ccoc6)[C@@]7(O[C@@H]7C(=O)O)[C@]4(C)C(=O)C[C@]13C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P21 compound treatment 111240.0 -53500.0 -1.43 147200.0 -16900.0 -0.46 -1.3348 -0.8885 3199903 SMP2_000348 C/C=C(/C)\C(=O)O[C@H]1C(=C[C@]2([C@H](C)C[C@H]3[C@@H](C3(C)C)[C@]4(C)C=C(CO)[C@@H](O)[C@@]12O)C4=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P22 compound treatment 121600.0 -43100.0 -1.15 140480.0 -23600.0 -0.64 -1.2675 -0.961 1048361 SMP2_000349 c1ccc2c(c1)[nH]c3cnccc32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P23 compound treatment 124480.0 -40300.0 -1.08 146120.0 -17900.0 -0.49 -1.1051 -0.9353 832145 SMP2_000350 OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H]2NC(=O)C(=O)N21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2099 P24 compound treatment 72960.0 -91800.0 -2.46 71080.0 -93000.0 -2.52 -3.516 -0.9999 2260 SMP2_000351 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(CO)c8c1c2c(c34)c(c65)c78 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A01 mock treatment 244920.0 69200.0 1.85 257520.0 78300.0 2.12 2.8068 0.9977 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A02 mock treatment 249920.0 74200.0 1.98 256400.0 77100.0 2.09 2.8799 0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A03 mock treatment 258800.0 83100.0 2.22 262760.0 83500.0 2.26 3.1696 1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A04 mock treatment 206000.0 30300.0 0.81 259000.0 79700.0 2.16 2.099 0.9104 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A05 mock treatment 189280.0 13500.0 0.36 248000.0 68700.0 1.86 1.5722 0.8292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A06 mock treatment 208800.0 33100.0 0.88 194800.0 15500.0 0.42 0.923 0.9423 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A07 mock treatment 220000.0 44300.0 1.18 227320.0 48100.0 1.3 1.7573 0.9989 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A08 mock treatment 224360.0 48600.0 1.3 224080.0 44800.0 1.21 1.7778 0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A09 mock treatment 217560.0 41800.0 1.12 240160.0 60900.0 1.65 1.957 0.9822 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A10 mock treatment 209520.0 33800.0 0.9 221480.0 42200.0 1.14 1.4473 0.9932 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A11 mock treatment 216960.0 41200.0 1.1 238320.0 59100.0 1.6 1.9104 0.9836 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A12 mock treatment 230280.0 54500.0 1.46 240600.0 61300.0 1.66 2.206 0.9979 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A13 mock treatment 224680.0 48900.0 1.31 244520.0 65300.0 1.77 2.1751 0.9891 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A14 mock treatment 219640.0 43900.0 1.17 258160.0 78900.0 2.14 2.3409 0.9603 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A15 mock treatment 234560.0 58800.0 1.57 279240.0 100000.0 2.71 3.0266 0.9667 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A16 mock treatment 200000.0 24300.0 0.65 243040.0 63800.0 1.73 1.68 0.9107 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A17 mock treatment 213720.0 38000.0 1.02 238720.0 59500.0 1.61 1.8568 0.9754 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A18 mock treatment 210600.0 34900.0 0.93 252840.0 73600.0 1.99 2.0681 0.9402 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A19 mock treatment 227800.0 52100.0 1.39 258120.0 78900.0 2.13 2.4945 0.9786 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A20 mock treatment 225040.0 49300.0 1.32 238960.0 59700.0 1.62 2.0755 0.9949 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A21 mock treatment 237000.0 61300.0 1.64 228560.0 49300.0 1.33 2.1026 0.9948 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A22 mock treatment 256960.0 81200.0 2.17 232200.0 52900.0 1.43 2.5498 0.9796 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A23 mock treatment 227360.0 51600.0 1.38 239880.0 60600.0 1.64 2.137 0.9963 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 A24 mock treatment 236680.0 60900.0 1.63 251800.0 72500.0 1.96 2.5415 0.9957 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B01 mock treatment 223360.0 47600.0 1.27 242680.0 63400.0 1.72 2.1149 0.9892 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B02 mock treatment 209720.0 34000.0 0.91 211560.0 32300.0 0.87 1.2612 0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B03 compound treatment 170160.0 -5570.0 -0.15 190160.0 10900.0 0.3 0.1033 0.3124 2277 HSCI1_000001 CCc1nc([nH]c1c2ccncc2)c3ccc(OC)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B04 compound treatment 12240.0 -163000.0 -4.37 15360.0 -164000.0 -4.44 -6.2299 -1.0 656 HSCI1_000002 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B05 compound treatment 145160.0 -30600.0 -0.82 145960.0 -33300.0 -0.9 -1.2157 -0.9988 2114187 HSCI1_000003 CCOC(=O)c1cccc(NC(=O)CBr)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B06 compound treatment 9320.0 -166000.0 -4.45 10640.0 -169000.0 -4.56 -6.3755 -0.9999 1362420 HSCI1_000004 Oc1c(I)cc(Cl)cc1C(=O)Nc2cc(ccc2Cl)S(=O)(=O)c3ccc(Cl)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B07 compound treatment 38560.0 -137000.0 -3.67 13960.0 -165000.0 -4.48 -5.7588 -0.9951 3175973 HSCI1_000005 COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B08 compound treatment 7800.0 -168000.0 -4.49 10960.0 -168000.0 -4.56 -6.3981 -1.0 3175974 HSCI1_000006 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1CCC(O)C(O)C1O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B09 compound treatment 65520.0 -110000.0 -2.95 71360.0 -108000.0 -2.92 -4.1501 -1.0 9 HSCI1_000007 [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B10 compound treatment 197080.0 21300.0 0.57 193040.0 13800.0 0.37 0.6676 0.9787 571 HSCI1_000008 CCCCCCCCCCCCCCCCCCOC[C@H](COC(=O)OC1C(O)C(O)C(O)C(CO)C1O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B11 mock treatment 175040.0 -692.0 -0.02 204280.0 25000.0 0.68 0.4659 0.6875 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B12 mock treatment 168320.0 -7410.0 -0.2 194400.0 15100.0 0.41 0.1497 0.3287 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B13 mock treatment 186760.0 11000.0 0.29 194080.0 14800.0 0.4 0.4923 0.9885 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B14 mock treatment 186480.0 10700.0 0.29 197480.0 18200.0 0.49 0.5521 0.967 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B15 compound treatment 169520.0 -6210.0 -0.17 209360.0 30100.0 0.81 0.4587 0.5516 3055039 HSCI1_000009 Cn1cnc2nc(NCCO)nc(NCc3ccccc3)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B16 compound treatment 10920.0 -165000.0 -4.41 14480.0 -165000.0 -4.46 -6.2717 -1.0 3175975 HSCI1_000010 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1C(O)C(O)C(O)CC1OC)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B17 compound treatment 9440.0 -166000.0 -4.45 12960.0 -166000.0 -4.5 -6.3288 -1.0 3055043 HSCI1_000011 CCCCCCCCCCCCCCC[C@@H](O)[C@H](N)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B18 compound treatment 10320.0 -165000.0 -4.42 13560.0 -166000.0 -4.49 -6.3006 -1.0 2326 HSCI1_000012 CCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B19 compound treatment 214160.0 38400.0 1.03 214280.0 35000.0 0.95 1.3973 0.9992 2026 HSCI1_000013 CCCCCCCCCCNc1cc(CO)c2cc[nH]c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B20 compound treatment 174800.0 -932.0 -0.02 188280.0 9020.0 0.24 0.1551 0.6316 193 HSCI1_000014 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B21 compound treatment 77120.0 -98600.0 -2.64 88160.0 -91100.0 -2.47 -3.6091 -0.9994 3055048 HSCI1_000015 Nc1nc(Cl)nc2n(cnc12)C3OC(CO)[C@H](O)[C@H]3F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B22 compound treatment 11360.0 -164000.0 -4.4 11360.0 -168000.0 -4.55 -6.3231 -0.9999 3175977 HSCI1_000016 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@]41OC(=O)CCCCCCCCC)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B23 mock treatment 191560.0 15800.0 0.42 211000.0 31700.0 0.86 0.907 0.9468 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 B24 mock treatment 251400.0 75700.0 2.02 271120.0 91900.0 2.49 3.1897 0.9948 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C01 mock treatment 213320.0 37600.0 1.01 207520.0 28300.0 0.77 1.252 0.9909 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C02 mock treatment 166320.0 -9410.0 -0.25 218800.0 39500.0 1.07 0.5789 0.5264 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C03 compound treatment 162360.0 -13400.0 -0.36 200920.0 21700.0 0.59 0.1617 0.2355 2257 HSCI1_000017 COc1ccc(cc1)C(=O)CBr 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C04 compound treatment 105280.0 -70500.0 -1.88 121040.0 -58200.0 -1.58 -2.447 -0.9961 561 HSCI1_000018 C[C@@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C05 compound treatment 143920.0 -31800.0 -0.85 189160.0 9900.0 0.27 -0.4122 -0.462 2256 HSCI1_000019 Oc1ccc(cc1)C(=O)CBr 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C06 compound treatment 93680.0 -82100.0 -2.19 107320.0 -71900.0 -1.95 -2.9291 -0.9982 1000099 HSCI1_000020 C[C@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C07 compound treatment 155160.0 -20600.0 -0.55 182240.0 2980.0 0.08 -0.332 -0.597 2258 HSCI1_000021 OC(=O)COc1ccc(cc1)C(=O)CBr 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C08 compound treatment 25640.0 -150000.0 -4.01 82080.0 -97200.0 -2.63 -4.6992 -0.979 2227 HSCI1_000022 CCCCCCCCCCCCCCCC(=O)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C09 compound treatment 10240.0 -165000.0 -4.43 13600.0 -166000.0 -4.48 -6.3014 -1.0 2147 HSCI1_000023 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(=O)(F)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C10 compound treatment 103640.0 -72100.0 -1.93 94600.0 -84700.0 -2.29 -2.9842 -0.9963 617 HSCI1_000024 COc1cc(OC)c(/C=C\2/C(=O)Nc3ccccc23)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C11 mock treatment 169840.0 -5890.0 -0.16 173040.0 -6220.0 -0.17 -0.2305 -0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C12 mock treatment 166640.0 -9090.0 -0.24 179720.0 462.0 0.01 -0.1631 -0.6699 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C13 mock treatment 171560.0 -4170.0 -0.11 198400.0 19100.0 0.52 0.2875 0.5424 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C14 mock treatment 163480.0 -12300.0 -0.33 188320.0 9060.0 0.25 -0.0583 -0.1424 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C15 mock treatment 169920.0 -5810.0 -0.16 185760.0 6500.0 0.18 0.0145 0.0618 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C16 mock treatment 155840.0 -19900.0 -0.53 193000.0 13700.0 0.37 -0.1132 -0.1743 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C17 compound treatment 154720.0 -21000.0 -0.56 187920.0 8660.0 0.23 -0.2316 -0.3803 3055108 HSCI1_000025 CSCC1OC([C@@H](O)[C@H]1O)n2ccc3c(N)ncnc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C18 compound treatment 10840.0 -165000.0 -4.41 14320.0 -165000.0 -4.47 -6.2763 -1.0 3055110 HSCI1_000026 ClCC(=O)c1cc(Br)c(Br)s1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C19 compound treatment 212640.0 36900.0 0.99 233320.0 54100.0 1.46 1.733 0.9816 2121 HSCI1_000027 Oc1ccc(cc1)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C20 compound treatment 188680.0 12900.0 0.35 217200.0 37900.0 1.03 0.9712 0.896 1916983 HSCI1_000028 CC(C)C(N1C(=O)/C(=C/c2ccccc2)/SC1=S)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C21 compound treatment 9160.0 -167000.0 -4.46 10800.0 -168000.0 -4.56 -6.3754 -0.9999 2188 HSCI1_000029 Oc1ccc(O)c2C(=O)C(=C(Cl)C(=O)c12)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C22 compound treatment 12320.0 -163000.0 -4.37 22800.0 -156000.0 -4.24 -6.0859 -0.9999 563 HSCI1_000030 Oc1ccc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C23 compound treatment 175320.0 -412.0 -0.01 169920.0 -9340.0 -0.25 -0.1866 -0.7373 1031143 HSCI1_000031 CS(=O)(=O)SCCN 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 C24 mock treatment 224560.0 48800.0 1.31 198720.0 19500.0 0.53 1.2961 0.9203 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D01 mock treatment 191760.0 16000.0 0.43 209680.0 30400.0 0.82 0.8855 0.9537 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D02 mock treatment 196960.0 21200.0 0.57 185760.0 6500.0 0.18 0.526 0.8848 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D03 compound treatment 22120.0 -154000.0 -4.11 26520.0 -153000.0 -4.14 -5.8294 -1.0 551 HSCI1_000032 CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D04 compound treatment 210840.0 35100.0 0.94 228920.0 49700.0 1.34 1.6147 0.9846 3479696 HSCI1_000033 OC(=O)C(CCCCNC(=O)CNC(=O)c1cccc(c1)C(=O)NCC(=O)NCCCCC(NC(=O)OCc2ccc(cc2)C(F)(F)F)C(=O)O)NC(=O)OCc3ccc(cc3)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D05 compound treatment 73320.0 -102000.0 -2.74 78480.0 -101000.0 -2.73 -3.8663 -1.0 674 HSCI1_000034 CCOC(=O)c1c(C)[nH]c(/C=C/2\C(=O)Nc3ccccc23)c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D06 compound treatment 11040.0 -165000.0 -4.41 13120.0 -166000.0 -4.5 -6.2954 -0.9999 146 HSCI1_000035 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D07 compound treatment 206360.0 30600.0 0.82 229080.0 49800.0 1.35 1.533 0.9714 3175981 HSCI1_000036 O=c1sn(Cc2ccccc2)c(=S)n1Cc3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D08 compound treatment 46120.0 -130000.0 -3.47 84560.0 -94700.0 -2.56 -4.2643 -0.989 1000097 HSCI1_000037 Cc1c(C)c2OC(C)(COc3ccc(CC4SC(=O)NC4=O)cc3)CCc2c(C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D09 compound treatment 160440.0 -15300.0 -0.41 221200.0 41900.0 1.14 0.5137 0.4256 628 HSCI1_000038 Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D10 compound treatment 199120.0 23400.0 0.63 204920.0 25700.0 0.69 0.9336 0.9986 3175982 HSCI1_000039 COc1ccc(Nc2nccc(NCCO)n2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D11 mock treatment 197720.0 22000.0 0.59 220680.0 41400.0 1.12 1.2088 0.9546 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D12 mock treatment 204880.0 29100.0 0.78 218840.0 39600.0 1.07 1.309 0.9878 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D13 mock treatment 193800.0 18100.0 0.48 229640.0 50400.0 1.36 1.3062 0.9027 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D14 mock treatment 191800.0 16100.0 0.43 246200.0 66900.0 1.81 1.5854 0.8512 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D15 mock treatment 182000.0 6270.0 0.17 205240.0 26000.0 0.7 0.6159 0.8518 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D16 mock treatment 169080.0 -6650.0 -0.18 240200.0 60900.0 1.65 1.0408 0.6272 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D17 compound treatment 148880.0 -26900.0 -0.72 165080.0 -14200.0 -0.38 -0.7793 -0.9569 584 HSCI1_000040 Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D18 compound treatment 77040.0 -98700.0 -2.64 106760.0 -72500.0 -1.96 -3.2545 -0.9893 2180 HSCI1_000041 COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C(C)C)c4n2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D19 compound treatment 141960.0 -33800.0 -0.9 184120.0 4860.0 0.13 -0.5457 -0.5978 3055161 HSCI1_000042 COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D20 compound treatment 161520.0 -14200.0 -0.38 174560.0 -4700.0 -0.13 -0.3588 -0.8949 2067 HSCI1_000043 CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D21 compound treatment 148120.0 -27600.0 -0.74 163120.0 -16100.0 -0.44 -0.8312 -0.9686 3055164 HSCI1_000044 N/C(=C(/C#N)\c1ccccc1C(F)(F)F)/Sc2ccc(N)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D22 compound treatment 188760.0 13000.0 0.35 176160.0 -3100.0 -0.08 0.1871 0.522 2407 HSCI1_000045 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ncc(C)s3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D23 compound treatment 20520.0 -155000.0 -4.15 47680.0 -132000.0 -3.56 -5.4546 -0.9971 550 HSCI1_000046 COC1=C(Br)[C@H](O)[C@](O)(CC#N)C=C1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 D24 mock treatment 183360.0 7630.0 0.2 197440.0 18200.0 0.49 0.4923 0.924 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E01 mock treatment 168120.0 -7610.0 -0.2 188480.0 9220.0 0.25 0.0325 0.101 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E02 mock treatment 161400.0 -14300.0 -0.38 203120.0 23900.0 0.65 0.1857 0.2472 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E03 mock treatment 180160.0 4430.0 0.12 207960.0 28700.0 0.78 0.6332 0.8056 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E04 mock treatment 154920.0 -20800.0 -0.56 197080.0 17800.0 0.48 -0.0525 -0.0713 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E05 compound treatment 166760.0 -8970.0 -0.24 212720.0 33500.0 0.91 0.4709 0.5024 2294 HSCI1_000047 CC(=O)NC(C(=O)O)C(C)(C)SN=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E06 compound treatment 152280.0 -23500.0 -0.63 205680.0 26400.0 0.72 0.0622 0.0654 3175983 HSCI1_000048 CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCC/C=C/C/C=C/C\C=C\C\C=C\CCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E07 compound treatment 129600.0 -46100.0 -1.23 135520.0 -43700.0 -1.18 -1.7099 -0.9998 640 HSCI1_000049 O=C/1Nc2ccccc2\C1=C\c3ccc[nH]3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E08 compound treatment 163960.0 -11800.0 -0.31 184320.0 5060.0 0.14 -0.1258 -0.3662 1907779 HSCI1_000050 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E09 mock treatment 142760.0 -33000.0 -0.88 183120.0 3860.0 0.1 -0.5497 -0.619 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E10 mock treatment 160640.0 -15100.0 -0.4 176400.0 -2860.0 -0.08 -0.3402 -0.8276 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E11 compound treatment 13560.0 -162000.0 -4.34 16040.0 -163000.0 -4.42 -6.1919 -1.0 627 HSCI1_000051 C=CC(=O)c1ccc2ccccc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E12 compound treatment 12720.0 -163000.0 -4.36 17200.0 -162000.0 -4.39 -6.1856 -1.0 536 HSCI1_000052 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E13 compound treatment 149280.0 -26500.0 -0.71 168840.0 -10400.0 -0.28 -0.6998 -0.9187 593 HSCI1_000053 Oc1ccc2ccc(=O)oc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E14 compound treatment 14520.0 -161000.0 -4.31 18640.0 -161000.0 -4.35 -6.124 -1.0 3055208 HSCI1_000054 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E15 mock treatment 174400.0 -1330.0 -0.04 189560.0 10300.0 0.28 0.172 0.6118 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E16 mock treatment 164000.0 -11700.0 -0.31 182760.0 3500.0 0.09 -0.1549 -0.4724 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E17 mock treatment 160680.0 -15100.0 -0.4 180320.0 1060.0 0.03 -0.2644 -0.655 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E18 mock treatment 153440.0 -22300.0 -0.6 170160.0 -9100.0 -0.25 -0.5958 -0.9235 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E19 compound treatment 208120.0 32400.0 0.87 214640.0 35400.0 0.96 1.2899 0.9987 1912 HSCI1_000055 [O-][N+](=O)c1cccc2cn[nH]c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E20 compound treatment 57160.0 -119000.0 -3.17 84680.0 -94600.0 -2.56 -4.0532 -0.9944 3175984 HSCI1_000056 CCCC(=O)OCSC(=S)OC1CC2CC1C3CCCC23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E21 compound treatment 144920.0 -30800.0 -0.82 147480.0 -31800.0 -0.86 -1.1911 -0.9998 596 HSCI1_000057 CN(C)c1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E22 compound treatment 11560.0 -164000.0 -4.39 15040.0 -164000.0 -4.45 -6.2489 -1.0 564 HSCI1_000058 Oc1ccc(/C=C(\C#N)/C(=O)NCCCCc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E23 compound treatment 35080.0 -141000.0 -3.76 95520.0 -83700.0 -2.27 -4.2634 -0.9706 2175 HSCI1_000059 CCCCCCCCN1C(=O)C(=C(C)C1(C)O)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 E24 mock treatment 173560.0 -2170.0 -0.06 177200.0 -2060.0 -0.06 -0.0805 -0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F01 mock treatment 168760.0 -6970.0 -0.19 199840.0 20600.0 0.56 0.2621 0.4461 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F02 mock treatment 200000.0 24300.0 0.65 208880.0 29600.0 0.8 1.0261 0.9945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F03 mock treatment 169440.0 -6290.0 -0.17 178800.0 -458.0 -0.01 -0.1278 -0.7572 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F04 mock treatment 185760.0 10000.0 0.27 255160.0 75900.0 2.05 1.6427 0.7927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F05 compound treatment 76360.0 -99400.0 -2.66 76320.0 -103000.0 -2.79 -3.8501 -0.9997 2108 HSCI1_000060 COc1cc2C/C(=C\c3cc(C)c(O)c(C)c3)/C(=O)c2c(N)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F06 compound treatment 174840.0 -892.0 -0.02 196680.0 17400.0 0.47 0.3166 0.6705 2303 HSCI1_000061 COc1cc2CCN3Cc4c(OC)c(O)ccc4CC3c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F07 compound treatment 117240.0 -58500.0 -1.56 120560.0 -58700.0 -1.59 -2.23 -1.0 1967 HSCI1_000062 Brc1cccc(Nc2ncnc3cc4[nH]cnc4cc23)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F08 compound treatment 25880.0 -150000.0 -4.01 96440.0 -82800.0 -2.24 -4.4198 -0.9623 1918768 HSCI1_000063 Clc1ccc(C(=O)n2nnc3ccccc23)c(Cl)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F09 mock treatment 161800.0 -13900.0 -0.37 196160.0 16900.0 0.46 0.06 0.1017 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F10 mock treatment 179040.0 3310.0 0.09 198720.0 19500.0 0.53 0.4351 0.8144 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F11 compound treatment 167880.0 -7850.0 -0.21 177320.0 -1940.0 -0.05 -0.1856 -0.8574 583 HSCI1_000064 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCCO)nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F12 compound treatment 156200.0 -19500.0 -0.52 186280.0 7020.0 0.19 -0.235 -0.4227 1085933 HSCI1_000065 COC(=O)c1ccccc1NC(=O)c2ccc(F)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F13 compound treatment 169120.0 -6610.0 -0.18 214120.0 34900.0 0.94 0.5423 0.5648 675 HSCI1_000066 Brc1ccc2NC(=O)/C(=C\c3cc4CCCCc4[nH]3)/c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F14 compound treatment 143280.0 -32500.0 -0.87 157400.0 -21900.0 -0.59 -1.0323 -0.9826 2144 HSCI1_000067 O=C(Nc1ccccc1)C2C(=O)NC(=S)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F15 mock treatment 162760.0 -13000.0 -0.35 186440.0 7180.0 0.19 -0.1079 -0.2712 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F16 mock treatment 158440.0 -17300.0 -0.46 198200.0 18900.0 0.51 0.0355 0.0514 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F17 mock treatment 166720.0 -9010.0 -0.24 178680.0 -578.0 -0.02 -0.1815 -0.7515 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F18 mock treatment 146320.0 -29400.0 -0.79 186440.0 7180.0 0.19 -0.4188 -0.5168 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F19 compound treatment 93120.0 -82600.0 -2.21 134480.0 -44800.0 -1.21 -2.4198 -0.96 643 HSCI1_000068 CNc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F20 compound treatment 48200.0 -128000.0 -3.41 66440.0 -113000.0 -3.05 -4.5719 -0.9985 122 HSCI1_000069 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F21 compound treatment 132840.0 -42900.0 -1.15 161560.0 -17700.0 -0.48 -1.1501 -0.925 590 HSCI1_000070 CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F22 compound treatment 149800.0 -25900.0 -0.69 223080.0 43800.0 1.19 0.3484 0.2535 2060831 HSCI1_000071 O=C1CCCC(=O)C1CC2C(=O)CCCC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F23 compound treatment 162840.0 -12900.0 -0.34 151320.0 -27900.0 -0.76 -0.7787 -0.9367 3176054 HSCI1_000072 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1)\[N+]#[C-])/Sc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 F24 mock treatment 174480.0 -1250.0 -0.03 177720.0 -1540.0 -0.04 -0.0531 -0.9942 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G01 mock treatment 181560.0 5830.0 0.16 177240.0 -2020.0 -0.05 0.0716 0.4334 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G02 compound treatment 11880.0 -164000.0 -4.38 13080.0 -166000.0 -4.5 -6.2803 -0.9999 305 HSCI1_000073 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G03 mock treatment 176440.0 708.0 0.02 173880.0 -5380.0 -0.15 -0.0896 -0.6101 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G04 mock treatment 191120.0 15400.0 0.41 226640.0 47400.0 1.28 1.1981 0.8893 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G05 mock treatment 164480.0 -11300.0 -0.3 210120.0 30900.0 0.84 0.378 0.4256 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G06 mock treatment 137360.0 -38400.0 -1.03 176120.0 -3140.0 -0.08 -0.7859 -0.763 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G07 compound treatment 10320.0 -165000.0 -4.42 12240.0 -167000.0 -4.52 -6.3259 -0.9999 2073 HSCI1_000074 CC(=CCC/C(=C/CC/C(=C/CSc1nc[nH]n1)/C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G08 compound treatment 150240.0 -25500.0 -0.68 152440.0 -26800.0 -0.73 -0.9956 -0.9995 3176055 HSCI1_000075 CCOc1cc(/C=C(/C#N)\C(=O)N)cc(CSc2ccccc2)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G09 compound treatment 151960.0 -23800.0 -0.64 158760.0 -20500.0 -0.55 -0.842 -0.9977 2335 HSCI1_000076 COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G10 compound treatment 20640.0 -155000.0 -4.15 42760.0 -136000.0 -3.7 -5.5465 -0.9983 3055275 HSCI1_000077 CC(C)(C)OC(=O)NC(CC(=O)CCl)C(=O)Cc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G11 compound treatment 12280.0 -163000.0 -4.37 15160.0 -164000.0 -4.44 -6.2329 -1.0 2134 HSCI1_000078 COc1cc(O)c(cc1/C=C/C(=O)c2ccc(O)cc2)C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G12 compound treatment 138200.0 -37500.0 -1.0 178680.0 -578.0 -0.02 -0.721 -0.718 3055277 HSCI1_000079 COc1cc(cc(CN(C)CCc2ccc(cc2)[N+](=O)[O-])c1O)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G13 compound treatment 152840.0 -22900.0 -0.61 190360.0 11100.0 0.3 -0.2205 -0.3232 1002387 HSCI1_000080 Oc1ccc(C=C(C#N)C#N)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G14 compound treatment 158280.0 -17500.0 -0.47 175120.0 -4140.0 -0.11 -0.4093 -0.8526 3176058 HSCI1_000081 C[C@@H]1[C@@H](O)[C@@]2(O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@]13O)C2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G15 compound treatment 161160.0 -14600.0 -0.39 170320.0 -8940.0 -0.24 -0.4467 -0.9737 672 HSCI1_000082 Oc1ccc(CC(C#N)C#N)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G16 compound treatment 129480.0 -46300.0 -1.24 127440.0 -51800.0 -1.4 -1.8668 -0.998 3176059 HSCI1_000083 OCc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G17 mock treatment 150840.0 -24900.0 -0.67 182720.0 3460.0 0.09 -0.4046 -0.6017 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G18 mock treatment 146840.0 -28900.0 -0.77 181600.0 2340.0 0.06 -0.5017 -0.6469 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G19 mock treatment 160440.0 -15300.0 -0.41 177600.0 -1660.0 -0.04 -0.321 -0.78 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G20 mock treatment 150680.0 -25100.0 -0.67 173240.0 -6020.0 -0.16 -0.5891 -0.8541 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G21 compound treatment 165480.0 -10300.0 -0.27 200080.0 20800.0 0.56 0.2047 0.3265 3415700 HSCI1_000084 CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G22 compound treatment 43840.0 -132000.0 -3.53 48760.0 -130000.0 -3.53 -4.9928 -1.0 3176060 HSCI1_000085 CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]4CCCC[C@@H]4N)nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G23 compound treatment 152000.0 -23700.0 -0.63 163000.0 -16300.0 -0.44 -0.7601 -0.984 3055326 HSCI1_000086 Cc1ccc(cc1)c2cn3c4CCCCc4sc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 G24 mock treatment 163280.0 -12500.0 -0.33 164280.0 -15000.0 -0.41 -0.5223 -0.9952 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H01 mock treatment 165200.0 -10500.0 -0.28 180320.0 1060.0 0.03 -0.1789 -0.6317 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H02 compound treatment 167120.0 -8610.0 -0.23 192240.0 13000.0 0.35 0.0856 0.2037 1886 HSCI1_000087 NCCOB(c1ccccc1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H03 mock treatment 157400.0 -18300.0 -0.49 184680.0 5420.0 0.15 -0.243 -0.4747 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H04 mock treatment 168360.0 -7370.0 -0.2 224120.0 44900.0 1.21 0.7193 0.5846 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H05 mock treatment 182160.0 6430.0 0.17 172480.0 -6780.0 -0.18 -0.0082 -0.0326 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H06 mock treatment 160960.0 -14800.0 -0.4 174920.0 -4340.0 -0.12 -0.3625 -0.8793 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H07 compound treatment 11640.0 -164000.0 -4.39 12720.0 -167000.0 -4.51 -6.2918 -0.9999 2278 HSCI1_000088 Oc1cc(ccc1NC(=O)Nc2ccccc2Br)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H08 compound treatment 15200.0 -161000.0 -4.29 17840.0 -161000.0 -4.37 -6.1264 -1.0 1891 HSCI1_000089 Clc1oc(=O)c2ccccc2c1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H09 compound treatment 132320.0 -43400.0 -1.16 130520.0 -48700.0 -1.32 -1.7541 -0.998 1966 HSCI1_000090 Cn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H10 compound treatment 164040.0 -11700.0 -0.31 166960.0 -12300.0 -0.33 -0.4566 -0.9995 3176061 HSCI1_000091 CC1(CCC2(C)O1)C(C2C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H11 compound treatment 133360.0 -42400.0 -1.13 177960.0 -1300.0 -0.04 -0.8263 -0.7287 291 HSCI1_000092 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H12 compound treatment 167000.0 -8730.0 -0.23 179800.0 542.0 0.01 -0.1548 -0.6614 3055333 HSCI1_000093 O=C/1Nc2ccccc2\C1=C/c3c[nH]cn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H13 compound treatment 145680.0 -30100.0 -0.8 156200.0 -23100.0 -0.62 -1.0098 -0.9922 3176062 HSCI1_000094 CC[C@@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H14 compound treatment 173120.0 -2610.0 -0.07 177120.0 -2140.0 -0.06 -0.0903 -0.9956 1040138 HSCI1_000095 COc1cc(C=O)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H15 compound treatment 151160.0 -24600.0 -0.66 163560.0 -15700.0 -0.42 -0.7653 -0.9777 3176063 HSCI1_000096 CC(C)n1cnc2c(NCc3ccccc3O)nc(NCCCO)nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H16 compound treatment 180600.0 4870.0 0.13 176400.0 -2860.0 -0.08 0.0373 0.2466 2109 HSCI1_000097 OCc1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H17 mock treatment 164560.0 -11200.0 -0.3 163320.0 -15900.0 -0.43 -0.5164 -0.9839 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H18 mock treatment 146480.0 -29300.0 -0.78 164440.0 -14800.0 -0.4 -0.837 -0.9518 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H19 mock treatment 152840.0 -22900.0 -0.61 197040.0 17800.0 0.48 -0.0926 -0.1189 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H20 mock treatment 164280.0 -11500.0 -0.31 179320.0 61.6 0.0 -0.2154 -0.7032 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H21 compound treatment 149640.0 -26100.0 -0.7 153720.0 -25500.0 -0.69 -0.9824 -1.0 3176064 HSCI1_000098 O/N=C\1/C(=C\2/C(=O)Nc3ccc(cc23)S(=O)(=O)O)/Nc4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H22 compound treatment 183880.0 8150.0 0.22 165760.0 -13500.0 -0.37 -0.1043 -0.2451 2069332 HSCI1_000099 CC(=O)/C(=N/O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H23 compound treatment 143560.0 -32200.0 -0.86 170440.0 -8820.0 -0.24 -0.7773 -0.8704 642 HSCI1_000100 COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 H24 mock treatment 168240.0 -7490.0 -0.2 160920.0 -18300.0 -0.5 -0.4928 -0.9204 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I01 mock treatment 171720.0 -4010.0 -0.11 196160.0 16900.0 0.46 0.2477 0.5269 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I02 compound treatment 73520.0 -102000.0 -2.73 62800.0 -116000.0 -3.15 -4.1627 -0.9975 666 HSCI1_000101 CC(C)c1cc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc(C(C)C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I03 compound treatment 11120.0 -165000.0 -4.4 11040.0 -168000.0 -4.55 -6.3338 -0.9999 3176066 HSCI1_000102 CCCCC/C=C/C/C=C/C\C=C\C\C=C\CCCC(=O)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I04 compound treatment 12440.0 -163000.0 -4.37 12920.0 -166000.0 -4.5 -6.2728 -0.9999 2104844 HSCI1_000103 Oc1ccc(O)c(CNc2ccc(cc2)C(=O)OC3(CC4CC5CC(C4)C3)C5)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I05 mock treatment 167120.0 -8610.0 -0.23 190120.0 10900.0 0.29 0.045 0.1205 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I06 mock treatment 175080.0 -652.0 -0.02 179080.0 -178.0 0.0 -0.0158 -0.8701 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I07 mock treatment 154200.0 -21500.0 -0.58 146360.0 -32900.0 -0.89 -1.037 -0.9777 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I08 mock treatment 179080.0 3350.0 0.09 174520.0 -4740.0 -0.13 -0.0274 -0.1751 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I09 compound treatment 13600.0 -162000.0 -4.34 14000.0 -165000.0 -4.47 -6.2302 -0.9999 626 HSCI1_000104 CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I10 compound treatment 163840.0 -11900.0 -0.32 154920.0 -24300.0 -0.66 -0.6908 -0.9442 3055340 HSCI1_000105 Cc1ccc(N/N=C/2\C(=O)Nc3ccc(Br)cc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I11 compound treatment 144880.0 -30900.0 -0.83 186560.0 7300.0 0.2 -0.4438 -0.5229 568 HSCI1_000106 COc1ccc(C=C(C#N)C#N)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I12 compound treatment 28680.0 -147000.0 -3.93 33480.0 -146000.0 -3.95 -5.572 -1.0 3176067 HSCI1_000107 Ic1cccc(CSc2nnc(o2)c3ccncc3)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I13 compound treatment 131680.0 -44100.0 -1.18 151480.0 -27800.0 -0.75 -1.365 -0.9765 558 HSCI1_000108 Oc1ccc(C=C(C#N)C#N)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I14 compound treatment 12160.0 -164000.0 -4.38 11720.0 -168000.0 -4.54 -6.3011 -0.9998 3176068 HSCI1_000109 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I15 compound treatment 15760.0 -160000.0 -4.28 15080.0 -164000.0 -4.44 -6.1687 -0.9998 1975 HSCI1_000110 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1c5ccc(=O)oc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I16 compound treatment 185800.0 10100.0 0.27 199880.0 20600.0 0.56 0.5852 0.9441 1001980 HSCI1_000111 CCCCCCCC/C=C/CCCCCCCC(=O)OCC(CO)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I17 compound treatment 12320.0 -163000.0 -4.37 12360.0 -167000.0 -4.52 -6.2858 -0.9999 130 HSCI1_000112 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I18 compound treatment 13880.0 -162000.0 -4.33 14640.0 -165000.0 -4.46 -6.2126 -0.9999 1922639 HSCI1_000113 CC(C)C(N1C(=O)/C(=C/c2ccc(Br)cc2)/SC1=S)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I19 mock treatment 171800.0 -3930.0 -0.11 164880.0 -14400.0 -0.39 -0.3496 -0.8671 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I20 mock treatment 149160.0 -26600.0 -0.71 179000.0 -258.0 -0.01 -0.5075 -0.714 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I21 mock treatment 159320.0 -16400.0 -0.44 170800.0 -8460.0 -0.23 -0.4723 -0.954 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I22 mock treatment 144920.0 -30800.0 -0.82 169960.0 -9300.0 -0.25 -0.7608 -0.8828 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I23 compound treatment 150520.0 -25200.0 -0.67 143680.0 -35600.0 -0.96 -1.158 -0.9848 565 HSCI1_000114 Oc1cc(C=C(C#N)C#N)cc(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 I24 mock treatment 171640.0 -4090.0 -0.11 165640.0 -13600.0 -0.37 -0.3381 -0.8791 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J01 mock treatment 195000.0 19300.0 0.52 178000.0 -1260.0 -0.03 0.3403 0.6589 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J02 compound treatment 40360.0 -135000.0 -3.62 40320.0 -139000.0 -3.76 -5.2202 -0.9998 3176070 HSCI1_000115 OC(=O)c1c(Br)c(Br)c(Br)c(Br)c1c2c3ccc(O)cc3oc4cc(=O)ccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J03 compound treatment 179600.0 3870.0 0.1 182560.0 3300.0 0.09 0.1364 0.9973 294 HSCI1_000116 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J04 compound treatment 177720.0 1990.0 0.05 210640.0 31400.0 0.85 0.6383 0.7499 3055387 HSCI1_000117 C[C@@]12CCC3C(CCC4=C[C@H](O)CCC34)C2CC[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J05 mock treatment 169400.0 -6330.0 -0.17 189840.0 10600.0 0.29 0.0828 0.2488 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J06 mock treatment 163360.0 -12400.0 -0.33 202600.0 23300.0 0.63 0.2128 0.2983 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J07 mock treatment 173440.0 -2290.0 -0.06 165840.0 -13400.0 -0.36 -0.3002 -0.8149 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J08 mock treatment 163800.0 -11900.0 -0.32 176560.0 -2700.0 -0.07 -0.2773 -0.847 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J09 compound treatment 173960.0 -1770.0 -0.05 168720.0 -10500.0 -0.29 -0.2353 -0.8135 633 HSCI1_000118 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J10 compound treatment 12200.0 -164000.0 -4.37 12280.0 -167000.0 -4.52 -6.2896 -0.9999 2251 HSCI1_000119 O=C(NC1=CC(=O)c2ccccc2C1=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J11 compound treatment 12080.0 -164000.0 -4.38 11720.0 -168000.0 -4.54 -6.3026 -0.9998 645 HSCI1_000120 Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J12 compound treatment 69360.0 -106000.0 -2.85 76480.0 -103000.0 -2.78 -3.9795 -0.9999 3176071 HSCI1_000121 Nc1nc(Cl)nc2n(cnc12)C3C[C@@H](O)C(CO)O3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J13 compound treatment 134680.0 -41100.0 -1.1 131040.0 -48200.0 -1.31 -1.6995 -0.9963 646 HSCI1_000122 CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J14 compound treatment 34480.0 -141000.0 -3.78 30320.0 -149000.0 -4.03 -5.5228 -0.9995 854065 HSCI1_000123 CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J15 compound treatment 188880.0 13100.0 0.35 186720.0 7460.0 0.2 0.3915 0.9653 670 HSCI1_000124 CN(C)S(=O)(=O)c1ccc2NC(=O)/C(=C\c3cc4CCCCc4[nH]3)/c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J16 compound treatment 89080.0 -86700.0 -2.32 52800.0 -126000.0 -3.42 -4.0598 -0.982 3176072 HSCI1_000125 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)c4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J17 compound treatment 52840.0 -123000.0 -3.29 59120.0 -120000.0 -3.25 -4.6242 -1.0 1996 HSCI1_000126 CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J18 compound treatment 148120.0 -27600.0 -0.74 149120.0 -30100.0 -0.82 -1.0992 -0.9988 2268 HSCI1_000127 CC(=CC1C(C(=O)OCc2coc(Cc3ccccc3)c2)C1(C)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J19 mock treatment 175880.0 148.0 0.0 162240.0 -17000.0 -0.46 -0.323 -0.701 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J20 mock treatment 146240.0 -29500.0 -0.79 188800.0 9540.0 0.26 -0.3752 -0.452 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J21 mock treatment 170720.0 -5010.0 -0.13 155600.0 -23700.0 -0.64 -0.5477 -0.837 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J22 mock treatment 149240.0 -26500.0 -0.71 205360.0 26100.0 0.71 -0.0014 -0.0014 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J23 compound treatment 51400.0 -124000.0 -3.33 31720.0 -148000.0 -3.99 -5.176 -0.9959 654 HSCI1_000128 CC(C)C(CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 J24 mock treatment 170400.0 -5330.0 -0.14 186920.0 7660.0 0.21 0.0458 0.182 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K01 mock treatment 199320.0 23600.0 0.63 176880.0 -2380.0 -0.06 0.4006 0.6317 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K02 compound treatment 184880.0 9150.0 0.24 202000.0 22700.0 0.62 0.6084 0.9183 3055432 HSCI1_000129 CCOC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cc(OC)c(OC)c(OC)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K03 compound treatment 160800.0 -14900.0 -0.4 162000.0 -17300.0 -0.47 -0.6128 -0.997 570 HSCI1_000130 NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K04 compound treatment 155560.0 -20200.0 -0.54 168360.0 -10900.0 -0.3 -0.5902 -0.9597 1005921 HSCI1_000131 OCC1OC(Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K05 compound treatment 170520.0 -5210.0 -0.14 168280.0 -11000.0 -0.3 -0.3087 -0.9405 559 HSCI1_000132 OC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K06 compound treatment 162680.0 -13100.0 -0.35 156760.0 -22500.0 -0.61 -0.6776 -0.9651 620 HSCI1_000133 COc1cc(/C=C(\C#N)/C(=O)c2ccc(O)c(O)c2)cc(I)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K07 mock treatment 171320.0 -4410.0 -0.12 157640.0 -21600.0 -0.59 -0.4973 -0.8329 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K08 mock treatment 163280.0 -12500.0 -0.33 157480.0 -21800.0 -0.59 -0.6524 -0.9635 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K09 mock treatment 152240.0 -23500.0 -0.63 188280.0 9020.0 0.24 -0.2716 -0.4029 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K10 mock treatment 170880.0 -4850.0 -0.13 157440.0 -21800.0 -0.59 -0.5095 -0.8424 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K11 compound treatment 172840.0 -2890.0 -0.08 182840.0 3580.0 0.1 0.0139 0.1117 553 HSCI1_000134 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K12 compound treatment 15160.0 -161000.0 -4.3 12960.0 -166000.0 -4.5 -6.2206 -0.9997 3176129 HSCI1_000135 Oc1cc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc(I)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K13 compound treatment 151880.0 -23900.0 -0.64 137760.0 -41500.0 -1.12 -1.2456 -0.9641 1000035 HSCI1_000136 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K14 compound treatment 94800.0 -80900.0 -2.16 41200.0 -138000.0 -3.74 -4.1736 -0.9663 1 HSCI1_000137 Oc1ccc(/C=C(\C#N)/C(=O)NCCCNC(=O)\C(=C\c2ccc(O)c(O)c2)\C#N)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K15 mock treatment 178440.0 2710.0 0.07 164360.0 -14900.0 -0.4 -0.234 -0.571 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K16 mock treatment 184160.0 8430.0 0.23 168440.0 -10800.0 -0.29 -0.0477 -0.1291 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K17 compound treatment 186720.0 11000.0 0.29 208960.0 29700.0 0.8 0.7764 0.9069 554 HSCI1_000138 Oc1cc(C=C(C#N)C#N)cc([N+](=O)[O-])c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K18 compound treatment 127280.0 -48500.0 -1.3 122400.0 -56900.0 -1.54 -2.0049 -0.9963 3176130 HSCI1_000139 CN(C)c1ccc2c(c3ccccc3C(=O)O)c4ccc(=[N+](C)C)cc4oc2c1.CC(=O)NCCSS(=O)(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K19 compound treatment 191000.0 15300.0 0.41 187120.0 7860.0 0.21 0.4393 0.9539 555 HSCI1_000140 Cc1cc2ncc(nc2cc1C)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K20 compound treatment 164240.0 -11500.0 -0.31 167240.0 -12000.0 -0.33 -0.4474 -0.9996 2311 HSCI1_000141 COC(=O)c1c(c2cc(OC)c(OC)c(OC)c2)c3ccnc(OCc4ncccn4)c3c(=O)n1Cc5ccnc(C)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K21 mock treatment 152400.0 -23300.0 -0.62 153160.0 -26100.0 -0.71 -0.9409 -0.9981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K22 mock treatment 149880.0 -25900.0 -0.69 151680.0 -27600.0 -0.75 -1.0169 -0.9993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K23 mock treatment 171280.0 -4450.0 -0.12 155200.0 -24100.0 -0.65 -0.5448 -0.8228 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 K24 mock treatment 178080.0 2350.0 0.06 175520.0 -3740.0 -0.1 -0.0272 -0.228 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L01 mock treatment 183000.0 7270.0 0.19 179200.0 -58.4 0.0 0.1363 0.7013 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L02 compound treatment 154480.0 -21300.0 -0.57 177480.0 -1780.0 -0.05 -0.436 -0.7643 1995 HSCI1_000142 CN(C1CCCCC1)C(=O)CCCOc2ccc3[nH]c(=O)ccc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L03 compound treatment 72600.0 -103000.0 -2.76 64680.0 -115000.0 -3.1 -4.1441 -0.9983 3176131 HSCI1_000143 Nc1ncnc2n(cc(I)c12)C3OC(CO)[C@H](O)[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L04 compound treatment 169880.0 -5850.0 -0.16 186480.0 7220.0 0.2 0.0276 0.11 3055484 HSCI1_000144 COc1cc(SC)ccc1c2nc3ccncc3[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L05 compound treatment 149680.0 -26100.0 -0.7 200000.0 20700.0 0.56 -0.0957 -0.1069 1907775 HSCI1_000145 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L06 compound treatment 21400.0 -154000.0 -4.13 13560.0 -166000.0 -4.49 -6.0911 -0.9991 3176132 HSCI1_000146 COc1ccc(cc1)C(=C2C(=O)Nc3ccccc23)c4ccc(OC)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L07 mock treatment 150600.0 -25100.0 -0.67 158160.0 -21100.0 -0.57 -0.8793 -0.9967 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L08 mock treatment 185760.0 10000.0 0.27 170360.0 -8900.0 -0.24 0.0193 0.0536 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L09 mock treatment 156440.0 -19300.0 -0.52 157440.0 -21800.0 -0.59 -0.7826 -0.9977 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L10 mock treatment 171560.0 -4170.0 -0.11 156640.0 -22600.0 -0.61 -0.5119 -0.8224 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L11 compound treatment 92640.0 -83100.0 -2.22 79960.0 -99300.0 -2.69 -3.4725 -0.9955 3055486 HSCI1_000147 O=C1NC(=O)c2c1c3c4ccccc4n5C6CCC(O6)n7c8ccccc8c2c7c53 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L12 compound treatment 102720.0 -73000.0 -1.95 97200.0 -82100.0 -2.22 -2.9518 -0.9979 3176133 HSCI1_000148 OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L13 compound treatment 70160.0 -106000.0 -2.82 49880.0 -129000.0 -3.5 -4.4735 -0.9943 3176134 HSCI1_000149 O/N=C\1/C(=C\2/C(=O)Nc3ccc(I)cc23)/Nc4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L14 compound treatment 160360.0 -15400.0 -0.41 175840.0 -3420.0 -0.09 -0.3562 -0.8451 3055490 HSCI1_000150 COc1cc(ccc1c2nc3ccncc3[nH]2)S(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L15 mock treatment 197160.0 21400.0 0.57 150080.0 -29200.0 -0.79 -0.1533 -0.1571 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L16 mock treatment 174240.0 -1490.0 -0.04 162000.0 -17300.0 -0.47 -0.3586 -0.7647 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L17 compound treatment 151440.0 -24300.0 -0.65 146120.0 -33100.0 -0.9 -1.0938 -0.9875 3176135 HSCI1_000151 C[S+](O)c1ccc(CSc2nc(c([nH]2)c3ccc(F)cc3)c4ccncc4)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L18 compound treatment 161120.0 -14600.0 -0.39 162280.0 -17000.0 -0.46 -0.6014 -0.9967 2109556 HSCI1_000152 Nc1n[nH]c2nc3ccccc3nc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L19 compound treatment 170240.0 -5490.0 -0.15 168320.0 -10900.0 -0.3 -0.3133 -0.9477 3176136 HSCI1_000153 C[C@@H]1C2NCC(C)C[C@H]2O[C@@]31CCC4C5CC=C6CC(O)CCC6(C)C5C(=O)C4=C3C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L20 compound treatment 42000.0 -134000.0 -3.58 29440.0 -150000.0 -4.06 -5.3974 -0.998 3055494 HSCI1_000154 OB(O)c1ccc(cc1)C(=O)/C=C/c2ccc(I)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L21 mock treatment 164960.0 -10800.0 -0.29 165800.0 -13500.0 -0.36 -0.4614 -0.9932 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L22 mock treatment 148680.0 -27100.0 -0.72 169840.0 -9420.0 -0.25 -0.692 -0.9019 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L23 mock treatment 156000.0 -19700.0 -0.53 185880.0 6620.0 0.18 -0.2465 -0.4421 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 L24 mock treatment 174600.0 -1130.0 -0.03 170880.0 -8380.0 -0.23 -0.1818 -0.7945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M01 mock treatment 206120.0 30400.0 0.81 177920.0 -1340.0 -0.04 0.5491 0.6749 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M02 compound treatment 12960.0 -163000.0 -4.35 12840.0 -166000.0 -4.51 -6.2645 -0.9999 2095175 HSCI1_000155 Oc1ccc(/C=C(\C#N)/C(=O)NC2CCC(CC3CCC(CC3)NC(=O)\C(=C\c4ccc(O)c(O)c4)\C#N)CC2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M03 compound treatment 181200.0 5470.0 0.15 165840.0 -13400.0 -0.36 -0.1535 -0.3919 552 HSCI1_000156 NC(=C(C#N)C#N)/C(=C/c1ccc(O)cc1)/C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M04 compound treatment 186240.0 10500.0 0.28 157360.0 -21900.0 -0.59 -0.2205 -0.336 613 HSCI1_000157 Oc1cc(/C=C/c2ccc(O)c(O)c2)oc(=O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M05 compound treatment 172480.0 -3250.0 -0.09 149840.0 -29400.0 -0.8 -0.6247 -0.7797 657 HSCI1_000158 COc1ccc(/C=C(\C#N)/c2cccnc2)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M06 compound treatment 161760.0 -14000.0 -0.37 157120.0 -22100.0 -0.6 -0.6881 -0.9742 3176139 HSCI1_000159 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCCC)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M07 compound treatment 159800.0 -15900.0 -0.43 169520.0 -9740.0 -0.26 -0.4878 -0.9733 671 HSCI1_000160 NC(=C(C#N)C#N)/C(=C/c1cc(O)c(O)c(O)c1)/C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M08 compound treatment 178480.0 2750.0 0.07 161840.0 -17400.0 -0.47 -0.2815 -0.5898 3176140 HSCI1_000161 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)[C@@H]3S 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M09 mock treatment 150840.0 -24900.0 -0.67 161840.0 -17400.0 -0.47 -0.8043 -0.9857 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M10 mock treatment 181960.0 6230.0 0.17 179560.0 302.0 0.01 0.1236 0.7409 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M11 mock treatment 183640.0 7910.0 0.21 162920.0 -16300.0 -0.44 -0.1632 -0.3329 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M12 mock treatment 171840.0 -3890.0 -0.1 214520.0 35300.0 0.95 0.6014 0.6263 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M13 mock treatment 162160.0 -13600.0 -0.36 171200.0 -8060.0 -0.22 -0.411 -0.9703 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M14 mock treatment 158840.0 -16900.0 -0.45 151400.0 -27900.0 -0.75 -0.8528 -0.97 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M15 compound treatment 54640.0 -121000.0 -3.24 69920.0 -109000.0 -2.96 -4.3835 -0.999 585 HSCI1_000162 Oc1ccc(C(=O)/C=C/c2ccc(O)c(O)c2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M16 compound treatment 140240.0 -35500.0 -0.95 133640.0 -45600.0 -1.24 -1.5446 -0.9916 2024 HSCI1_000163 CN(N=O)c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M17 compound treatment 20960.0 -155000.0 -4.14 15320.0 -164000.0 -4.44 -6.0657 -0.9994 569 HSCI1_000164 COC(=O)c1ccc(NCc2cc(O)ccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M18 compound treatment 181440.0 5710.0 0.15 157160.0 -22100.0 -0.6 -0.3151 -0.5103 1890 HSCI1_000165 CN(N=O)c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M19 compound treatment 154640.0 -21100.0 -0.56 161040.0 -18200.0 -0.49 -0.7477 -0.9978 1008455 HSCI1_000166 BrCC(=O)c1ccc(Br)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M20 compound treatment 174600.0 -1130.0 -0.03 145280.0 -34000.0 -0.92 -0.6719 -0.73 3176141 HSCI1_000167 CCN(N=O)c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M21 compound treatment 63400.0 -112000.0 -3.0 58200.0 -121000.0 -3.28 -4.4421 -0.9991 560 HSCI1_000168 Oc1ccc(/C=C(\C#N)/C(=O)Nc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M22 compound treatment 170280.0 -5450.0 -0.15 151240.0 -28000.0 -0.76 -0.6395 -0.8279 566 HSCI1_000169 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M23 mock treatment 175440.0 -292.0 -0.01 177200.0 -2060.0 -0.06 -0.0449 -0.7985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 M24 mock treatment 179120.0 3390.0 0.09 175520.0 -3740.0 -0.1 -0.0075 -0.0551 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N01 mock treatment 191200.0 15500.0 0.41 212400.0 33100.0 0.9 0.927 0.9382 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N02 compound treatment 180640.0 4910.0 0.13 209840.0 30600.0 0.83 0.6783 0.8091 837968 HSCI1_000170 Nc1ncnc2n(cnc12)C3CCCO3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N03 compound treatment 178680.0 2950.0 0.08 179640.0 382.0 0.01 0.0631 0.793 3176143 HSCI1_000171 CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)CCC(=O)O)[C@@]3(C)O[C@](C)(CC(=O)[C@@]32O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N04 compound treatment 11760.0 -164000.0 -4.39 8360.0 -171000.0 -4.63 -6.3729 -0.9996 831810 HSCI1_000172 Brc1c(Br)c(Br)c2[nH]nnc2c1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N05 compound treatment 8760.0 -167000.0 -4.47 7320.0 -172000.0 -4.65 -6.4496 -0.9998 3054768 HSCI1_000173 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C\[C@H](O)CCC[C@@H](C)C/C=C\[C@H]4C(=O)C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N06 compound treatment 10480.0 -165000.0 -4.42 8880.0 -170000.0 -4.61 -6.3872 -0.9998 3054769 HSCI1_000174 Cn1sc(=O)n(Cc2ccccc2)c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N07 compound treatment 49720.0 -126000.0 -3.37 87320.0 -91900.0 -2.49 -4.1434 -0.9889 621 HSCI1_000175 CS(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4cccc(I)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N08 compound treatment 131600.0 -44100.0 -1.18 109800.0 -69500.0 -1.88 -2.1644 -0.9748 3054770 HSCI1_000176 c1ccc(cc1)c2n[nH]c3c2oc4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N09 mock treatment 205920.0 30200.0 0.81 164360.0 -14900.0 -0.4 0.2858 0.3166 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N10 mock treatment 165720.0 -10000.0 -0.27 154040.0 -25200.0 -0.68 -0.6721 -0.9165 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N11 mock treatment 178480.0 2750.0 0.07 157240.0 -22000.0 -0.6 -0.3695 -0.6153 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N12 mock treatment 174800.0 -932.0 -0.02 151520.0 -27700.0 -0.75 -0.5486 -0.7302 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N13 mock treatment 197920.0 22200.0 0.59 182120.0 2860.0 0.08 0.4744 0.7927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N14 mock treatment 175200.0 -532.0 -0.01 209680.0 30400.0 0.82 0.5723 0.6948 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N15 compound treatment 109640.0 -66100.0 -1.77 112440.0 -66800.0 -1.81 -2.5292 -0.9999 3176144 HSCI1_000177 CC1C2C(Cc3ccccc3)NC(=O)C42OC(=O)O/C=C\C(C)(O)C(=O)C(C)C/C=C\C4C5OC51C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N16 compound treatment 198440.0 22700.0 0.61 173960.0 -5300.0 -0.14 0.3281 0.5257 1056418 HSCI1_000178 Nc1ncnc2n(cnc12)C3CCC(CO)O3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N17 compound treatment 182680.0 6950.0 0.19 146040.0 -33200.0 -0.9 -0.5045 -0.5494 2177 HSCI1_000179 CC(C)CC[C@@H](O)[C@](C)(O)C1CC[C@@]2(O)C3=CC(=O)[C@]4(O)C[C@@H](O)[C@@H](O)C[C@]4(C)C3[C@H](O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N18 compound treatment 126840.0 -48900.0 -1.31 126400.0 -52900.0 -1.43 -1.9366 -0.999 3054771 HSCI1_000180 COc1ccc2NC(=O)/C(=C\c3c[nH]cn3)/c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N19 compound treatment 137880.0 -37900.0 -1.01 142040.0 -37200.0 -1.01 -1.4284 -1.0 3176146 HSCI1_000181 CCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCC)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N20 compound treatment 10760.0 -165000.0 -4.41 8240.0 -171000.0 -4.63 -6.3942 -0.9997 2127 HSCI1_000182 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N21 compound treatment 24320.0 -151000.0 -4.05 18680.0 -161000.0 -4.35 -5.9378 -0.9994 3054772 HSCI1_000183 CC(C)(O)/C=C/C(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4C(C=C(O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N22 compound treatment 60640.0 -115000.0 -3.08 16840.0 -162000.0 -4.4 -5.2861 -0.9848 1937872 HSCI1_000184 [O-][N+](=O)c1ccccc1c2ccc(C=C3C(=O)N(C(=S)N(C3=O)c4ccccc4)c5ccccc5)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N23 mock treatment 154880.0 -20900.0 -0.56 156800.0 -22500.0 -0.61 -0.8243 -0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 N24 mock treatment 172200.0 -3530.0 -0.09 174520.0 -4740.0 -0.13 -0.1575 -0.9887 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O01 mock treatment 216720.0 41000.0 1.1 229960.0 50700.0 1.37 1.7458 0.9938 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O02 mock treatment 158720.0 -17000.0 -0.46 170720.0 -8540.0 -0.23 -0.4852 -0.9507 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O03 compound treatment 11160.0 -165000.0 -4.4 9520.0 -170000.0 -4.6 -6.3621 -0.9998 5 HSCI1_000185 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O04 compound treatment 34640.0 -141000.0 -3.77 15560.0 -164000.0 -4.43 -5.8024 -0.9968 2090 HSCI1_000186 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O05 compound treatment 21000.0 -155000.0 -4.14 8840.0 -170000.0 -4.61 -6.189 -0.9985 2107241 HSCI1_000187 ClC1=C(N2C(=O)CCC2=O)C(=O)c3ccccc3C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O06 compound treatment 157960.0 -17800.0 -0.48 153840.0 -25400.0 -0.69 -0.8227 -0.9837 651 HSCI1_000188 Nc1ncnc2n(ncc12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O07 compound treatment 133120.0 -42600.0 -1.14 111320.0 -67900.0 -1.84 -2.1065 -0.9735 562 HSCI1_000189 Oc1ccc(/C=C(\C#N)/C(=O)c2ccc(O)c(O)c2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O08 compound treatment 177520.0 1790.0 0.05 178120.0 -1140.0 -0.03 0.012 0.2113 3176147 HSCI1_000190 CS/C(=C(\C#N)/C(=C(\N)/SC)/[N+]#[C-])/N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O09 compound treatment 177360.0 1630.0 0.04 127960.0 -51300.0 -1.39 -0.9512 -0.6846 3176148 HSCI1_000191 OCc1cc2ncnc(Nc3ccc(O)cc3)c2cc1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O10 compound treatment 89680.0 -86100.0 -2.3 11600.0 -168000.0 -4.54 -4.8371 -0.9505 3054774 HSCI1_000192 Nc1ccc(cc1)c2cc(=O)c3cc(O)ccc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O11 mock treatment 157560.0 -18200.0 -0.49 159800.0 -19500.0 -0.53 -0.7162 -0.9992 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O12 mock treatment 163640.0 -12100.0 -0.32 158560.0 -20700.0 -0.56 -0.625 -0.9659 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O13 mock treatment 54920.0 -121000.0 -3.23 49400.0 -130000.0 -3.52 -4.771 -0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O14 mock treatment 189440.0 13700.0 0.37 146600.0 -32700.0 -0.88 -0.3659 -0.3823 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O15 compound treatment 16480.0 -159000.0 -4.26 11200.0 -168000.0 -4.55 -6.2293 -0.9995 3176208 HSCI1_000193 COc1ccc(N=O)c(CCc2cc(OC)ccc2N=O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O16 compound treatment 153520.0 -22200.0 -0.59 169760.0 -9500.0 -0.26 -0.602 -0.9298 3054775 HSCI1_000194 CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)OCCF 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O17 compound treatment 126720.0 -49000.0 -1.31 151520.0 -27700.0 -0.75 -1.458 -0.965 1860 HSCI1_000195 CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O18 compound treatment 158720.0 -17000.0 -0.46 135840.0 -43400.0 -1.18 -1.1529 -0.9147 634 HSCI1_000196 OC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O19 compound treatment 180480.0 4750.0 0.13 165120.0 -14100.0 -0.38 -0.1809 -0.4485 589 HSCI1_000197 Nc1cc(Nc2ccc(cc2)S(=O)(=O)N)ncn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O20 compound treatment 42480.0 -133000.0 -3.56 28200.0 -151000.0 -4.09 -5.4121 -0.9977 3054776 HSCI1_000198 Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O21 compound treatment 100280.0 -75500.0 -2.02 103120.0 -76100.0 -2.06 -2.8847 -0.9999 557 HSCI1_000199 Cc1cc2ncc(nc2cc1C)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O22 compound treatment 12280.0 -163000.0 -4.37 8280.0 -171000.0 -4.63 -6.3646 -0.9996 1000586 HSCI1_000200 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O23 mock treatment 173960.0 -1770.0 -0.05 164200.0 -15100.0 -0.41 -0.3218 -0.7841 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 O24 mock treatment 184520.0 8790.0 0.24 182400.0 3140.0 0.09 0.2264 0.9055 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P01 mock treatment 204680.0 28900.0 0.77 188680.0 9420.0 0.26 0.7279 0.8928 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P02 mock treatment 163840.0 -11900.0 -0.32 165920.0 -13300.0 -0.36 -0.4803 -0.998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P03 mock treatment 168920.0 -6810.0 -0.18 165360.0 -13900.0 -0.38 -0.3949 -0.9446 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P04 mock treatment 158280.0 -17500.0 -0.47 175640.0 -3620.0 -0.1 -0.3994 -0.8373 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P05 mock treatment 173040.0 -2690.0 -0.07 148200.0 -31100.0 -0.84 -0.6455 -0.7649 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P06 mock treatment 167720.0 -8010.0 -0.21 159360.0 -19900.0 -0.54 -0.5325 -0.9184 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P07 mock treatment 161840.0 -13900.0 -0.37 154600.0 -24700.0 -0.67 -0.7348 -0.9618 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P08 mock treatment 187320.0 11600.0 0.31 154320.0 -24900.0 -0.68 -0.2582 -0.3476 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P09 mock treatment 166000.0 -9730.0 -0.26 152120.0 -27100.0 -0.73 -0.7036 -0.9027 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P10 mock treatment 175920.0 188.0 0.01 150880.0 -28400.0 -0.77 -0.5397 -0.7025 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P11 mock treatment 178120.0 2390.0 0.06 151960.0 -27300.0 -0.74 -0.4774 -0.6436 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P12 mock treatment 169080.0 -6650.0 -0.18 162160.0 -17100.0 -0.46 -0.4531 -0.9137 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P13 mock treatment 186760.0 11000.0 0.29 144840.0 -34400.0 -0.93 -0.4503 -0.4607 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P14 mock treatment 170560.0 -5170.0 -0.14 134240.0 -45000.0 -1.22 -0.9596 -0.7824 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P15 mock treatment 165880.0 -9850.0 -0.26 134800.0 -44500.0 -1.2 -1.0374 -0.842 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P16 mock treatment 160960.0 -14800.0 -0.4 151640.0 -27600.0 -0.75 -0.8081 -0.9556 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P17 mock treatment 194080.0 18300.0 0.49 140080.0 -39200.0 -1.06 -0.403 -0.3448 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P18 mock treatment 171880.0 -3850.0 -0.1 145680.0 -33600.0 -0.91 -0.7157 -0.7823 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P19 mock treatment 157720.0 -18000.0 -0.48 146200.0 -33100.0 -0.89 -0.9735 -0.9578 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P20 mock treatment 151560.0 -24200.0 -0.65 156560.0 -22700.0 -0.61 -0.8917 -0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P21 mock treatment 160720.0 -15000.0 -0.4 150640.0 -28600.0 -0.77 -0.8318 -0.9532 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P22 mock treatment 152280.0 -23500.0 -0.63 170520.0 -8740.0 -0.24 -0.6109 -0.9111 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P23 mock treatment 143440.0 -32300.0 -0.86 151800.0 -27500.0 -0.74 -1.1364 -0.9972 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2104 P24 mock treatment 183680.0 7950.0 0.21 175600.0 -3660.0 -0.1 0.0803 0.3423 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A01 mock treatment 250680.0 73900.0 1.98 164520.0 -5110.0 -0.14 1.3004 0.6561 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A02 mock treatment 256280.0 79500.0 2.13 190120.0 20500.0 0.55 1.8964 0.8627 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A03 mock treatment 263440.0 86700.0 2.32 168760.0 -868.0 -0.02 1.6229 0.6999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A04 mock treatment 223360.0 46600.0 1.25 177600.0 7970.0 0.22 1.0341 0.8174 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A05 mock treatment 235360.0 58600.0 1.57 211480.0 41900.0 1.13 1.9096 0.9873 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A06 mock treatment 234960.0 58200.0 1.56 177320.0 7690.0 0.21 1.2481 0.7946 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A07 mock treatment 260600.0 83800.0 2.24 193240.0 23600.0 0.64 2.0378 0.8739 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A08 mock treatment 210360.0 33600.0 0.9 184200.0 14600.0 0.39 0.9145 0.9317 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A09 mock treatment 210000.0 33200.0 0.89 163760.0 -5870.0 -0.16 0.5164 0.5717 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A10 mock treatment 237520.0 60800.0 1.63 184000.0 14400.0 0.39 1.4244 0.8523 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A11 mock treatment 146320.0 -30400.0 -0.81 189160.0 19500.0 0.53 -0.2018 -0.2079 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A12 mock treatment 237720.0 61000.0 1.63 200840.0 31200.0 0.84 1.7506 0.9532 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A13 mock treatment 234960.0 58200.0 1.56 200520.0 30900.0 0.84 1.6922 0.9575 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A14 mock treatment 213040.0 36300.0 0.97 200040.0 30400.0 0.82 1.2684 0.9967 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A15 mock treatment 236360.0 59600.0 1.59 160960.0 -8670.0 -0.23 0.9614 0.5966 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A16 mock treatment 222080.0 45300.0 1.21 175760.0 6130.0 0.17 0.9746 0.7965 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A17 mock treatment 242640.0 65900.0 1.76 168080.0 -1550.0 -0.04 1.2165 0.6901 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A18 mock treatment 238840.0 62100.0 1.66 182120.0 12500.0 0.34 1.4134 0.834 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A19 mock treatment 218520.0 41800.0 1.12 183400.0 13800.0 0.37 1.0535 0.8946 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A20 mock treatment 244120.0 67400.0 1.8 164360.0 -5270.0 -0.14 1.1733 0.6491 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A21 mock treatment 208560.0 31800.0 0.85 161080.0 -8550.0 -0.23 0.4379 0.4967 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A22 mock treatment 221920.0 45200.0 1.21 155280.0 -14300.0 -0.39 0.5795 0.4567 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A23 mock treatment 266960.0 90200.0 2.41 160360.0 -9270.0 -0.25 1.5287 0.6302 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 A24 mock treatment 246280.0 69500.0 1.86 164120.0 -5510.0 -0.15 1.2095 0.6483 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B01 mock treatment 271760.0 95000.0 2.54 193240.0 23600.0 0.64 2.2489 0.8582 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B02 mock treatment 225080.0 48300.0 1.29 190040.0 20400.0 0.55 1.3047 0.9281 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B03 compound treatment 29680.0 -147000.0 -3.93 23080.0 -147000.0 -3.97 -5.5873 -1.0 577 HSCI1_000201 CN1C(=O)C(=C(C1=O)c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B04 compound treatment 195280.0 18500.0 0.5 177080.0 7450.0 0.2 0.493 0.9216 614 HSCI1_000202 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c65 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B05 compound treatment 172400.0 -4360.0 -0.12 196480.0 26900.0 0.73 0.4316 0.5862 907102 HSCI1_000203 NCCCCCCNS(=O)(=O)c1cccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B06 compound treatment 183000.0 6240.0 0.17 194160.0 24500.0 0.66 0.5877 0.8582 1012954 HSCI1_000204 OC(Cc1ccncc1)C(Cl)(Cl)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B07 compound treatment 99320.0 -77400.0 -2.07 100960.0 -68700.0 -1.86 -2.7792 -0.9985 3176210 HSCI1_000205 CCCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B08 compound treatment 163120.0 -13600.0 -0.36 162520.0 -7110.0 -0.19 -0.394 -0.9553 321 HSCI1_000206 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B09 compound treatment 12480.0 -164000.0 -4.39 14440.0 -155000.0 -4.2 -6.078 -0.9997 3176211 HSCI1_000207 C[C@@H](O)[C@]1(C)CC[C@@H](O1)[C@]2(C)CC[C@@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C/C[C@@H](C)C[C@@H](C)/C(=C/C(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(=O)O)/O)O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B10 compound treatment 179400.0 2640.0 0.07 173400.0 3770.0 0.1 0.1222 0.9838 3103895 HSCI1_000208 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B11 mock treatment 188280.0 11500.0 0.31 172440.0 2810.0 0.08 0.2718 0.856 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B12 mock treatment 181400.0 4640.0 0.12 178680.0 9050.0 0.25 0.2611 0.9504 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B13 mock treatment 186240.0 9480.0 0.25 172800.0 3170.0 0.09 0.2401 0.8965 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B14 mock treatment 193480.0 16700.0 0.45 168040.0 -1590.0 -0.04 0.2859 0.6362 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B15 compound treatment 14560.0 -162000.0 -4.34 34640.0 -135000.0 -3.65 -5.6519 -0.9964 1940 HSCI1_000209 NSC(=S)N1CCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B16 compound treatment 194240.0 17500.0 0.47 175560.0 5930.0 0.16 0.4442 0.8984 1000071 HSCI1_000210 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B17 compound treatment 178240.0 1480.0 0.04 183960.0 14300.0 0.39 0.3024 0.7753 3176212 HSCI1_000211 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B18 compound treatment 169080.0 -7680.0 -0.21 164840.0 -4790.0 -0.13 -0.2369 -0.9754 831767 HSCI1_000212 NCCCNCCCCNCCCN 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B19 compound treatment 155240.0 -21500.0 -0.58 179280.0 9650.0 0.26 -0.2222 -0.3515 3054778 HSCI1_000213 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B20 compound treatment 203800.0 27000.0 0.72 166040.0 -3590.0 -0.1 0.4428 0.6067 2293 HSCI1_000214 CSC(=N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B21 compound treatment 177320.0 562.0 0.02 169160.0 -468.0 -0.01 0.0017 0.0854 1001920 HSCI1_000215 CNC[C@H](O)c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B22 compound treatment 196640.0 19900.0 0.53 160000.0 -9630.0 -0.26 0.1918 0.3238 3054779 HSCI1_000216 CN/C(=N\C)/NCCC[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B23 mock treatment 216000.0 39200.0 1.05 168440.0 -1190.0 -0.03 0.7195 0.6851 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 B24 mock treatment 260960.0 84200.0 2.25 159640.0 -9990.0 -0.27 1.4014 0.6178 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C01 mock treatment 229680.0 52900.0 1.42 165960.0 -3670.0 -0.1 0.9308 0.6559 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C02 mock treatment 188560.0 11800.0 0.32 197320.0 27700.0 0.75 0.7533 0.9261 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C03 compound treatment 168800.0 -7960.0 -0.21 164160.0 -5470.0 -0.15 -0.2552 -0.9842 2022 HSCI1_000217 CC1(C)C(C=C(Br)Br)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C04 compound treatment 195680.0 18900.0 0.51 218520.0 48900.0 1.32 1.2939 0.913 3176214 HSCI1_000218 COc1ccc2c(cc(C)c3nnc(SCC(=O)Nc4cccc(c4)C(=O)C)n32)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C05 compound treatment 134160.0 -42600.0 -1.14 125400.0 -44200.0 -1.2 -1.6524 -0.9997 3054780 HSCI1_000219 CCCCc1c([nH]c2nccnc12)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C06 compound treatment 33280.0 -143000.0 -3.84 38640.0 -131000.0 -3.55 -5.2213 -0.9992 3054781 HSCI1_000220 NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+](=O)[O-])cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C07 compound treatment 132000.0 -44800.0 -1.2 127640.0 -42000.0 -1.14 -1.6503 -0.9997 360 HSCI1_000221 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C08 compound treatment 37520.0 -139000.0 -3.72 23640.0 -146000.0 -3.95 -5.4282 -0.9996 2260 HSCI1_000222 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(CO)c8c1c2c(c34)c(c65)c78 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C09 compound treatment 178000.0 1240.0 0.03 199080.0 29500.0 0.8 0.5873 0.7359 3054782 HSCI1_000223 O=c1cc(oc2c1ccc3ccccc32)N4CCOCC4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C10 compound treatment 121440.0 -55300.0 -1.48 109360.0 -60300.0 -1.63 -2.2 -0.9988 3176215 HSCI1_000224 C1CCC(CC1)n2cnc3c(Nc4ccc(cc4)N5CCOCC5)nc(Oc6cccc7ccccc67)nc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C11 mock treatment 169320.0 -7440.0 -0.2 181120.0 11500.0 0.31 0.0793 0.2148 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C12 mock treatment 192120.0 15400.0 0.41 176320.0 6690.0 0.18 0.4187 0.9323 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C13 mock treatment 178920.0 2160.0 0.06 163160.0 -6470.0 -0.18 -0.0829 -0.4496 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C14 mock treatment 197720.0 21000.0 0.56 177240.0 7610.0 0.21 0.5422 0.9076 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C15 mock treatment 190480.0 13700.0 0.37 168480.0 -1150.0 -0.03 0.2376 0.6449 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C16 mock treatment 162480.0 -14300.0 -0.38 186560.0 16900.0 0.46 0.0541 0.0906 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C17 compound treatment 163000.0 -13800.0 -0.37 168840.0 -788.0 -0.02 -0.2753 -0.7468 3176216 HSCI1_000225 CCCCCCCCCCCCCCCCC(=C)OOCC(COP(=O)(ON)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(=O)(O)ON)[C@H](OP(=O)(O)ON)[C@H]1O)OOC(=C)CC/C=C/C/C=C/C\C=C\C\C=C\CCCCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C18 compound treatment 163560.0 -13200.0 -0.35 172240.0 2610.0 0.07 -0.1996 -0.5544 907140 HSCI1_000226 NCCCCNS(=O)(=O)c1ccc2ccccc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C19 compound treatment 175000.0 -1760.0 -0.05 169960.0 332.0 0.01 -0.0269 -0.5617 3054783 HSCI1_000227 Nc1nc2n(cnc2c(=O)[nH]1)C3OC(COP(=O)(O)OP(=S)(O)O)[C@H](O)[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C20 compound treatment 22840.0 -154000.0 -4.12 25080.0 -145000.0 -3.91 -5.6783 -0.9997 2081802 HSCI1_000228 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C21 compound treatment 151880.0 -24900.0 -0.67 192800.0 23200.0 0.63 -0.027 -0.0295 3176218 HSCI1_000229 Nc1nc2n(C3OC4COP(O)(O)OC4C3O)c(Br)nc2c(=O)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C22 compound treatment 65760.0 -111000.0 -2.97 74800.0 -94800.0 -2.57 -3.9147 -0.9974 3054784 HSCI1_000230 Nc1nc(Cl)nc2n(cnc12)C3C[C@@H](O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C23 compound treatment 148440.0 -28300.0 -0.76 168440.0 -1190.0 -0.03 -0.5583 -0.7365 1338 HSCI1_000231 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 C24 mock treatment 212200.0 35400.0 0.95 156920.0 -12700.0 -0.34 0.4271 0.4235 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D01 mock treatment 217840.0 41100.0 1.1 215680.0 46100.0 1.25 1.6586 0.998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D02 mock treatment 216160.0 39400.0 1.05 194720.0 25100.0 0.68 1.2256 0.9774 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D03 compound treatment 11280.0 -165000.0 -4.43 11000.0 -159000.0 -4.29 -6.1665 -0.9999 3176219 HSCI1_000232 O/N=C/1\C(=C/2\C(=O)Nc3cc(Br)ccc23)\Nc4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D04 compound treatment 54440.0 -122000.0 -3.27 73960.0 -95700.0 -2.59 -4.1449 -0.9933 3054785 HSCI1_000233 O=C1NC(=O)c2c1ccc(Nc3ccccc3)c2Nc4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D05 compound treatment 60000.0 -117000.0 -3.12 155560.0 -14100.0 -0.38 -2.4777 -0.7875 1277018 HSCI1_000234 COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D06 compound treatment 28560.0 -148000.0 -3.96 34840.0 -135000.0 -3.65 -5.3833 -0.9991 1919 HSCI1_000235 CCCCCc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D07 compound treatment 158120.0 -18600.0 -0.5 166200.0 -3430.0 -0.09 -0.4181 -0.8246 3176221 HSCI1_000236 C1C[C@H](N/C/2=N/CCCCCCCCCCC2)[C@@H](C1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D08 compound treatment 203960.0 27200.0 0.73 196080.0 26500.0 0.72 1.0209 1.0 3054786 HSCI1_000237 OCC1OC([C@@H](O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D09 compound treatment 55720.0 -121000.0 -3.24 119000.0 -50600.0 -1.37 -3.2585 -0.9268 3176222 HSCI1_000238 COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D10 compound treatment 204400.0 27600.0 0.74 218880.0 49300.0 1.33 1.4657 0.9613 407 HSCI1_000239 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D11 mock treatment 175960.0 -798.0 -0.02 204640.0 35000.0 0.95 0.6552 0.691 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D12 mock treatment 196440.0 19700.0 0.53 189680.0 20100.0 0.54 0.7561 0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D13 mock treatment 187280.0 10500.0 0.28 213960.0 44300.0 1.2 1.0477 0.8499 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D14 mock treatment 161560.0 -15200.0 -0.41 213040.0 43400.0 1.18 0.5436 0.4371 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D15 mock treatment 178520.0 1760.0 0.05 214280.0 44700.0 1.21 0.8881 0.7341 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D16 mock treatment 171560.0 -5200.0 -0.14 197080.0 27500.0 0.74 0.4272 0.565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D17 compound treatment 168120.0 -8640.0 -0.23 197640.0 28000.0 0.76 0.3729 0.4703 3054787 HSCI1_000240 N/N=C(/N)\NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D18 compound treatment 214920.0 38200.0 1.02 181520.0 11900.0 0.32 0.9495 0.887 907294 HSCI1_000241 CN(C)C(=N)NCCC[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D19 compound treatment 165880.0 -10900.0 -0.29 249120.0 79500.0 2.15 1.316 0.606 3176223 HSCI1_000242 CSC(=N)NCCC[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D20 compound treatment 181640.0 4880.0 0.13 177080.0 7450.0 0.2 0.235 0.9778 3054789 HSCI1_000243 CNC(=N)NCCC[C@@H](N)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D21 compound treatment 180520.0 3760.0 0.1 173320.0 3690.0 0.1 0.1418 1.0 3176224 HSCI1_000244 OP(=O)(O)C(Cl)(Cl)P(=O)(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D22 compound treatment 218120.0 41400.0 1.11 175120.0 5490.0 0.15 0.8875 0.795 3176225 HSCI1_000245 CNC(=N)NCCC[C@H](N)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D23 compound treatment 176720.0 -37.6 0.0 213520.0 43900.0 1.19 0.8395 0.7065 2215 HSCI1_000246 CCCNC(=N)NCCCC(N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 D24 mock treatment 186680.0 9920.0 0.27 184600.0 15000.0 0.41 0.4743 0.9789 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E01 mock treatment 176560.0 -198.0 -0.01 161640.0 -7990.0 -0.22 -0.1567 -0.7242 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E02 mock treatment 174040.0 -2720.0 -0.07 192760.0 23100.0 0.63 0.3914 0.6209 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E03 mock treatment 206240.0 29500.0 0.79 169200.0 -428.0 -0.01 0.5494 0.6966 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E04 mock treatment 161040.0 -15700.0 -0.42 176440.0 6810.0 0.18 -0.1669 -0.3635 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E05 compound treatment 197120.0 20400.0 0.54 200920.0 31300.0 0.85 0.9842 0.9772 3176226 HSCI1_000247 CCCCc1c([nH]c2nccnc12)c3ccc(OC)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E06 compound treatment 50680.0 -126000.0 -3.37 116800.0 -52800.0 -1.43 -3.396 -0.9271 2371 HSCI1_000248 CCCCCCCCNC(=O)C(Cc1ccc(OCc2ccncc2)cc1)NC(=O)C3CCC(CN)CC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E07 compound treatment 8800.0 -168000.0 -4.49 10840.0 -159000.0 -4.3 -6.2165 -0.9998 1989 HSCI1_000249 Clc1[nH]c2ccccc2c1/C=C\3/C(=O)Nc4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E08 compound treatment 9440.0 -167000.0 -4.48 11600.0 -158000.0 -4.28 -6.1898 -0.9997 1416171 HSCI1_000250 OC(CN1CCNCC1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E09 mock treatment 155040.0 -21700.0 -0.58 156480.0 -13100.0 -0.36 -0.6625 -0.9724 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E10 mock treatment 153440.0 -23300.0 -0.62 188640.0 19000.0 0.51 -0.0771 -0.0953 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E11 compound treatment 138480.0 -38300.0 -1.02 128400.0 -41200.0 -1.12 -1.5132 -0.9991 663 HSCI1_000251 Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E12 compound treatment 57240.0 -120000.0 -3.2 61840.0 -108000.0 -2.92 -4.324 -0.999 1000089 HSCI1_000252 COC1C(C)OC(OC2CC(C)(O)C(C(=O)OC)c3cc4C(=O)c5c6OC7OC(C)(C(O)C(C7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)C(OC)C1(C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E13 compound treatment 167160.0 -9600.0 -0.26 166920.0 -2710.0 -0.07 -0.2334 -0.8741 3054791 HSCI1_000253 Nc1nc2n(cnc2c(=O)[nH]1)C3OC4COP(O)(O)OC4C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E14 compound treatment 177480.0 722.0 0.02 169880.0 252.0 0.01 0.0185 0.9022 3176276 HSCI1_000254 NCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-])C(=O)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E15 mock treatment 163200.0 -13600.0 -0.36 182280.0 12700.0 0.34 -0.0142 -0.0285 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E16 mock treatment 164000.0 -12800.0 -0.34 182600.0 13000.0 0.35 0.007 0.0143 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E17 mock treatment 158160.0 -18600.0 -0.5 156640.0 -13000.0 -0.35 -0.6004 -0.9856 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E18 mock treatment 147560.0 -29200.0 -0.78 169400.0 -228.0 -0.01 -0.5566 -0.7127 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E19 compound treatment 175560.0 -1200.0 -0.03 153080.0 -16500.0 -0.45 -0.3394 -0.7557 1000095 HSCI1_000255 CC(O)C(O)[C@H]1CNc2nc(N)[nH]c(=O)c2N1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E20 compound treatment 179320.0 2560.0 0.07 176200.0 6570.0 0.18 0.1743 0.914 3054834 HSCI1_000256 NCCNC[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E21 compound treatment 183160.0 6400.0 0.17 155480.0 -14100.0 -0.38 -0.1497 -0.3569 423 HSCI1_000257 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E22 compound treatment 198280.0 21500.0 0.58 155320.0 -14300.0 -0.39 0.1332 0.1919 2114444 HSCI1_000258 O=c1n(CCN2CCCCC2)c(=O)c3ccc4c5ccc6c(=O)n(CCN7CCCCC7)c(=O)c8ccc(c9ccc1c3c94)c5c86 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E23 compound treatment 191080.0 14300.0 0.38 155200.0 -14400.0 -0.39 -0.0053 -0.0097 832002 HSCI1_000259 CC(=N)NCCC[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 E24 mock treatment 159680.0 -17100.0 -0.46 155320.0 -14300.0 -0.39 -0.5969 -0.9966 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F01 mock treatment 188120.0 11400.0 0.3 272440.0 103000.0 2.78 2.1831 0.7797 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F02 mock treatment 204640.0 27900.0 0.75 196440.0 26800.0 0.73 1.0406 0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F03 mock treatment 176960.0 202.0 0.01 187600.0 18000.0 0.49 0.3479 0.7149 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F04 mock treatment 171760.0 -5000.0 -0.13 227600.0 58000.0 1.57 1.0152 0.6445 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F05 compound treatment 12240.0 -165000.0 -4.4 13360.0 -156000.0 -4.23 -6.1032 -0.9998 3176278 HSCI1_000260 CC(=O)O/N=C/1\C(=C/2\C(=O)Nc3cc(Br)ccc23)\Nc4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F06 compound treatment 180000.0 3240.0 0.09 196680.0 27100.0 0.73 0.5792 0.7854 1505 HSCI1_000261 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F07 compound treatment 83440.0 -93300.0 -2.5 74560.0 -95100.0 -2.57 -3.5849 -0.9999 3054836 HSCI1_000262 COc1ccc(CNc2nc(nc3n(cnc23)C(C)C)N(CCO)CCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F08 compound treatment 41600.0 -135000.0 -3.62 43760.0 -126000.0 -3.41 -4.9659 -0.9996 1980 HSCI1_000263 CC1(C2CCC(O2)C1(C)C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F09 mock treatment 180640.0 3880.0 0.1 183960.0 14300.0 0.39 0.3478 0.8659 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F10 mock treatment 168760.0 -8000.0 -0.21 178560.0 8930.0 0.24 0.0197 0.0611 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F11 compound treatment 136280.0 -40500.0 -1.08 139680.0 -29900.0 -0.81 -1.3389 -0.9898 832084 HSCI1_000264 NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c4nc[nH]c4n2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F12 compound treatment 175200.0 -1560.0 -0.04 207720.0 38100.0 1.03 0.6997 0.678 445 HSCI1_000265 NC(=O)c1cccc(N)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F13 compound treatment 170400.0 -6360.0 -0.17 171320.0 1690.0 0.05 -0.0879 -0.4988 2194 HSCI1_000266 OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(c3)[N+](=O)[O-])ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F14 compound treatment 179440.0 2680.0 0.07 164160.0 -5470.0 -0.15 -0.0539 -0.3279 2025 HSCI1_000267 NCCCC(N)(C(F)F)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F15 mock treatment 161360.0 -15400.0 -0.41 174960.0 5330.0 0.14 -0.1892 -0.4334 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F16 mock treatment 182360.0 5600.0 0.15 176760.0 7130.0 0.19 0.2425 0.9921 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F17 mock treatment 157040.0 -19700.0 -0.53 177840.0 8210.0 0.22 -0.2157 -0.3769 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F18 mock treatment 176720.0 -37.6 0.0 177880.0 8250.0 0.22 0.1573 0.7039 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F19 compound treatment 160880.0 -15900.0 -0.42 182520.0 12900.0 0.35 -0.0535 -0.0974 2259 HSCI1_000268 CN1CCc2cc3OCOc3cc2C(=O)Cc4ccc5OCOc5c4C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F20 compound treatment 183320.0 6560.0 0.18 167200.0 -2430.0 -0.07 0.0776 0.4142 2674 HSCI1_000269 N[C@@H](CCC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F21 compound treatment 75800.0 -101000.0 -2.7 74120.0 -95500.0 -2.59 -3.7379 -0.9998 3176279 HSCI1_000270 CC[C@]1(O)C[C@H]2CN(C1)CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)[C@@H]7[C@@]86CCN9CC=C[C@@](CC)([C@H]98)[C@@H](OC(=O)C)[C@]7(O)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F22 compound treatment 140760.0 -36000.0 -0.96 181040.0 11400.0 0.31 -0.4624 -0.4573 2129 HSCI1_000271 OCC(O)C1OC(=O)C(=C1O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F23 compound treatment 42400.0 -134000.0 -3.59 41160.0 -128000.0 -3.48 -5.0006 -0.9999 1000078 HSCI1_000272 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 F24 mock treatment 165040.0 -11700.0 -0.31 163720.0 -5910.0 -0.16 -0.3347 -0.9512 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G01 mock treatment 178480.0 1720.0 0.05 163880.0 -5750.0 -0.16 -0.0775 -0.4773 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G02 compound treatment 22960.0 -154000.0 -4.11 12880.0 -157000.0 -4.24 -5.9096 -0.9999 25 HSCI1_000273 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G03 mock treatment 179160.0 2400.0 0.06 174160.0 4530.0 0.12 0.1322 0.9545 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G04 mock treatment 192240.0 15500.0 0.41 169080.0 -548.0 -0.01 0.2823 0.6813 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G05 mock treatment 197680.0 20900.0 0.56 164920.0 -4710.0 -0.13 0.3056 0.5324 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G06 mock treatment 154320.0 -22400.0 -0.6 147360.0 -22300.0 -0.6 -0.8507 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G07 compound treatment 11160.0 -166000.0 -4.43 11400.0 -158000.0 -4.28 -6.1611 -0.9999 3054838 HSCI1_000274 CC(C)(c1ccc(NS(=O)(=O)C(F)(F)F)cc1)c2ccc(cc2)C(C)(C)c3cccc(NS(=O)(=O)C(F)(F)F)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G08 compound treatment 159760.0 -17000.0 -0.45 169320.0 -308.0 -0.01 -0.3274 -0.72 546 HSCI1_000275 Cc1ncc2ccccc2c1C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G09 compound treatment 11800.0 -165000.0 -4.41 12960.0 -157000.0 -4.24 -6.1192 -0.9998 1947905 HSCI1_000276 Clc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G10 compound treatment 126720.0 -50000.0 -1.34 130920.0 -38700.0 -1.05 -1.6874 -0.9927 636 HSCI1_000277 C/C(=C(\C#N)/C(=O)Nc1cccc(F)c1)/O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G11 compound treatment 25240.0 -152000.0 -4.05 27000.0 -143000.0 -3.86 -5.5962 -0.9997 3176281 HSCI1_000278 COc1ccc(CNC(=O)Nc2ncc(s2)[N+](=O)[O-])cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G12 compound treatment 148040.0 -28700.0 -0.77 164240.0 -5390.0 -0.15 -0.6463 -0.8266 3054840 HSCI1_000279 CC1OC(C[C@H]1O)n2cnc3c(N)ncnc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G13 compound treatment 14080.0 -163000.0 -4.35 16160.0 -153000.0 -4.15 -6.0148 -0.9997 2319 HSCI1_000280 CN(C)CC1Cc2ccccc2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G14 compound treatment 164040.0 -12700.0 -0.34 167320.0 -2310.0 -0.06 -0.2847 -0.8232 3176282 HSCI1_000281 N[C@@H](CCN/C(=N/O)/N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G15 compound treatment 135560.0 -41200.0 -1.1 134560.0 -35100.0 -0.95 -1.4505 -0.9972 2145 HSCI1_000282 NC(=N)NCCS 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G16 compound treatment 174200.0 -2560.0 -0.07 174200.0 4570.0 0.12 0.0391 0.2768 3583 HSCI1_000283 Cn1cc(NC(=O)c2cc(NC(=O)CNC(=N)N)cn2C)cc1C(=O)NCCC(=N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G17 mock treatment 169560.0 -7200.0 -0.19 171040.0 1410.0 0.04 -0.1091 -0.5558 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G18 mock treatment 155160.0 -21600.0 -0.58 159200.0 -10400.0 -0.28 -0.6081 -0.9458 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G19 mock treatment 171120.0 -5640.0 -0.15 161440.0 -8190.0 -0.22 -0.2634 -0.9824 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G20 mock treatment 157600.0 -19200.0 -0.51 160280.0 -9350.0 -0.25 -0.5413 -0.9471 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G21 compound treatment 171680.0 -5080.0 -0.14 166720.0 -2910.0 -0.08 -0.1517 -0.9664 1030173 HSCI1_000284 NC(=N)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G22 compound treatment 138200.0 -38600.0 -1.03 142080.0 -27500.0 -0.75 -1.2566 -0.9873 3176283 HSCI1_000285 COc1cc(ccc1[n+]2nc(nn2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)c5ccc(c(OC)c5)[n+]6nc(nn6c7ccc(cc7)[N+](=O)[O-])c8ccccc8 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G23 compound treatment 155200.0 -21600.0 -0.58 161920.0 -7710.0 -0.21 -0.5553 -0.9055 469 HSCI1_000286 CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 G24 mock treatment 151800.0 -25000.0 -0.67 161320.0 -8310.0 -0.22 -0.6311 -0.8959 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H01 mock treatment 174000.0 -2760.0 -0.07 182520.0 12900.0 0.35 0.1946 0.5456 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H02 compound treatment 173720.0 -3040.0 -0.08 164080.0 -5550.0 -0.15 -0.1637 -0.9584 1594 HSCI1_000287 N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H03 mock treatment 174000.0 -2760.0 -0.07 176920.0 7290.0 0.2 0.0874 0.4149 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H04 mock treatment 188600.0 11800.0 0.32 210200.0 40600.0 1.1 1.0007 0.8754 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H05 mock treatment 162320.0 -14400.0 -0.39 171040.0 1410.0 0.04 -0.246 -0.634 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H06 mock treatment 176920.0 162.0 0.0 192440.0 22800.0 0.62 0.4398 0.7121 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H07 compound treatment 14560.0 -162000.0 -4.34 15280.0 -154000.0 -4.18 -6.0226 -0.9998 3054842 HSCI1_000288 CSc1nc(c([nH]1)c2ccnc(NC(C)c3ccccc3)c2)c4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H08 compound treatment 199720.0 23000.0 0.61 189160.0 19500.0 0.53 0.8082 0.9972 1961 HSCI1_000289 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H09 compound treatment 75400.0 -101000.0 -2.71 81640.0 -88000.0 -2.38 -3.6015 -0.9979 572 HSCI1_000290 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H10 compound treatment 168200.0 -8560.0 -0.23 159160.0 -10500.0 -0.28 -0.3622 -0.9944 1907755 HSCI1_000291 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H11 compound treatment 42120.0 -135000.0 -3.6 54120.0 -116000.0 -3.13 -4.7578 -0.9975 574 HSCI1_000292 NCCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H12 compound treatment 113520.0 -63200.0 -1.69 114120.0 -55500.0 -1.5 -2.2587 -0.9983 3176284 HSCI1_000293 COc1cc2C3CC[C@]4(C)[C@@H](O)CCC4C3CCc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H13 compound treatment 149200.0 -27600.0 -0.74 167040.0 -2590.0 -0.07 -0.5708 -0.7708 2195 HSCI1_000294 OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c3)ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H14 compound treatment 157120.0 -19600.0 -0.53 164240.0 -5390.0 -0.15 -0.4746 -0.8705 1714 HSCI1_000295 CN(C)C(=N)NC(=N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H15 compound treatment 158800.0 -18000.0 -0.48 177000.0 7370.0 0.2 -0.1985 -0.3817 2197 HSCI1_000296 OS(=O)(=O)c1ccc(NC(=O)c2cc(NC(=O)Nc3cc(cc(c3)C(=O)Nc4ccc(cc4S(=O)(=O)O)S(=O)(=O)O)C(=O)Nc5ccc(cc5S(=O)(=O)O)S(=O)(=O)O)cc(c2)C(=O)Nc6ccc(cc6S(=O)(=O)O)S(=O)(=O)O)c(c1)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H16 compound treatment 174040.0 -2720.0 -0.07 171240.0 1610.0 0.04 -0.0205 -0.2423 3054849 HSCI1_000297 CCNC(=N)NCCC[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H17 mock treatment 163560.0 -13200.0 -0.35 173520.0 3890.0 0.11 -0.1751 -0.4753 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H18 mock treatment 162920.0 -13800.0 -0.37 155840.0 -13800.0 -0.37 -0.5257 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H19 mock treatment 160640.0 -16100.0 -0.43 170160.0 532.0 0.01 -0.2947 -0.6831 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H20 mock treatment 164480.0 -12300.0 -0.33 154800.0 -14800.0 -0.4 -0.5161 -0.995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H21 compound treatment 14160.0 -163000.0 -4.35 13560.0 -156000.0 -4.23 -6.063 -0.9999 3054896 HSCI1_000298 NC(=O)c1cn(C2OC(CO)[C@H](O)[C@@H]2O)c3ncnc(N)c13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H22 compound treatment 176040.0 -718.0 -0.02 163320.0 -6310.0 -0.17 -0.1343 -0.7817 2063 HSCI1_000299 CCOC(=O)c1cnc2n(CC)ncc2c1NN=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H23 compound treatment 81880.0 -94900.0 -2.54 70080.0 -99500.0 -2.7 -3.7002 -0.9995 606 HSCI1_000300 CNCCNS(=O)(=O)c1cccc2cnccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 H24 mock treatment 180960.0 4200.0 0.11 151920.0 -17700.0 -0.48 -0.2595 -0.527 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I01 mock treatment 186240.0 9480.0 0.25 180400.0 10800.0 0.29 0.3856 0.9976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I02 compound treatment 178520.0 1760.0 0.05 213400.0 43800.0 1.19 0.8713 0.7347 662 HSCI1_000301 Cc1nc(c(o1)c2ccncc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I03 compound treatment 154920.0 -21800.0 -0.58 159560.0 -10100.0 -0.27 -0.6058 -0.9398 3054901 HSCI1_000302 Clc1cc(Cl)c(NC(=O)Nc2ccncc2)c(Cl)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I04 compound treatment 162400.0 -14400.0 -0.38 174560.0 4930.0 0.13 -0.1771 -0.4357 2110413 HSCI1_000303 Cc1cc(C)c(/C=C/2\C(=O)Nc3ccccc23)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I05 mock treatment 176720.0 -37.6 0.0 163960.0 -5670.0 -0.15 -0.1092 -0.7117 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I06 mock treatment 197760.0 21000.0 0.56 157440.0 -12200.0 -0.33 0.1639 0.2516 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I07 mock treatment 186040.0 9280.0 0.25 157120.0 -12500.0 -0.34 -0.0639 -0.1521 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I08 mock treatment 179960.0 3200.0 0.09 177320.0 7690.0 0.21 0.2078 0.9229 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I09 compound treatment 174560.0 -2200.0 -0.06 179600.0 9970.0 0.27 0.1493 0.5405 2023 HSCI1_000304 CCCCn1c(=O)n(CCCC)c2ncn(CC(=O)C)c2c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I10 compound treatment 166920.0 -9840.0 -0.26 176520.0 6890.0 0.19 -0.0541 -0.1678 2196 HSCI1_000305 OS(=O)(=O)c1cc(c2c(NC(=O)c3ccc(NC(=O)c4ccc(NC(=O)Nc5ccc(cc5)C(=O)Nc6ccc(cc6)C(=O)Nc7ccc(c8cc(cc(c78)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)cc4)cc3)ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I11 compound treatment 104360.0 -72400.0 -1.94 107480.0 -62100.0 -1.68 -2.5591 -0.9975 3054905 HSCI1_000306 Oc1ccc(cc1O)C(=O)/C(=C/c2ccc3oc(=O)[nH]c3c2)/C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I12 compound treatment 162760.0 -14000.0 -0.37 181560.0 11900.0 0.32 -0.0363 -0.0735 3054907 HSCI1_000307 Cc1nc2cc3nc(cnc3cc2n1C)c4cccs4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I13 compound treatment 165480.0 -11300.0 -0.3 158080.0 -11500.0 -0.31 -0.4344 -0.9998 3479224 HSCI1_000308 CC(=N)NCCCCC(N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I14 compound treatment 13480.0 -163000.0 -4.37 13800.0 -156000.0 -4.22 -6.0713 -0.9998 2061 HSCI1_000309 Oc1cc(c2cc(ccc2c1N=Nc3ccc4ccccc4c3O)[N+](=O)[O-])S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I15 compound treatment 165840.0 -10900.0 -0.29 151360.0 -18300.0 -0.49 -0.5562 -0.9684 2087 HSCI1_000310 NC(CCC(=O)NC(CSN=O)C(=O)NCC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I16 compound treatment 182880.0 6120.0 0.16 172520.0 2890.0 0.08 0.1712 0.9429 1870 HSCI1_000311 NC(=N)SCCc1cccc(CCSC(=N)N)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I17 compound treatment 133360.0 -43400.0 -1.16 142000.0 -27600.0 -0.75 -1.3497 -0.9774 2408 HSCI1_000312 NCCC(O)(P(=O)(O)O)P(=O)(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I18 compound treatment 178040.0 1280.0 0.03 158080.0 -11500.0 -0.31 -0.1968 -0.6258 3054955 HSCI1_000313 Cc1ccc(cc1)S(=O)(=O)N[C@H](CCCCN)C(=O)CCl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I19 mock treatment 161480.0 -15300.0 -0.41 169800.0 172.0 0.0 -0.2857 -0.699 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I20 mock treatment 159280.0 -17500.0 -0.47 187040.0 17400.0 0.47 0.0027 0.0041 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I21 mock treatment 160560.0 -16200.0 -0.43 167160.0 -2470.0 -0.07 -0.3536 -0.8066 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I22 mock treatment 146080.0 -30700.0 -0.82 159440.0 -10200.0 -0.28 -0.7753 -0.8955 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I23 compound treatment 204800.0 28000.0 0.75 159920.0 -9710.0 -0.26 0.3446 0.4335 1956 HSCI1_000314 N[C@H](CSCCB(O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 I24 mock treatment 164360.0 -12400.0 -0.33 190840.0 21200.0 0.57 0.1716 0.2587 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J01 mock treatment 175400.0 -1360.0 -0.04 184480.0 14900.0 0.4 0.2586 0.6406 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J02 compound treatment 113280.0 -63500.0 -1.7 98080.0 -71500.0 -1.94 -2.5703 -0.9978 1005830 HSCI1_000315 Cc1cc(ccc1N=Nc2cc(c3ccccc3c2N)S(=O)(=O)O)c4ccc(N=Nc5cc(c6ccccc6c5N)S(=O)(=O)O)c(C)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J03 compound treatment 152920.0 -23800.0 -0.64 120400.0 -49200.0 -1.33 -1.3932 -0.943 573 HSCI1_000316 CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J04 compound treatment 10880.0 -166000.0 -4.44 9880.0 -160000.0 -4.32 -6.1955 -0.9999 1038990 HSCI1_000317 FC(F)(F)c1ccc2Sc3ccccc3N(CCCN4CCN(CCCl)CC4)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J05 mock treatment 158160.0 -18600.0 -0.5 173400.0 3770.0 0.1 -0.2795 -0.5505 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J06 mock treatment 180960.0 4200.0 0.11 158080.0 -11500.0 -0.31 -0.1416 -0.4262 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J07 mock treatment 158320.0 -18400.0 -0.49 180240.0 10600.0 0.29 -0.1456 -0.2551 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J08 mock treatment 172000.0 -4760.0 -0.13 162840.0 -6790.0 -0.18 -0.2199 -0.9839 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J09 compound treatment 133440.0 -43300.0 -1.16 128120.0 -41500.0 -1.12 -1.6139 -0.9999 3054961 HSCI1_000318 OCc1cc2ncnc(Nc3cc(Br)c(O)c(Br)c3)c2cc1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J10 compound treatment 13240.0 -164000.0 -4.37 13320.0 -156000.0 -4.23 -6.085 -0.9999 1979 HSCI1_000319 Clc1ccc(cc1)C(c2ccc(Cl)cc2)[n+]3ccn(CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J11 compound treatment 28480.0 -148000.0 -3.97 60640.0 -109000.0 -2.95 -4.8909 -0.9894 580 HSCI1_000320 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCN)c4ccccc34)c5ccccc15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J12 compound treatment 171360.0 -5400.0 -0.14 153640.0 -16000.0 -0.43 -0.4082 -0.8945 3054964 HSCI1_000321 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CCC[C@]2(C)C3C(=O)C[C@@](C)(O[C@]13C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J13 compound treatment 151720.0 -25000.0 -0.67 143960.0 -25700.0 -0.69 -0.9649 -0.9998 907101 HSCI1_000322 NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J14 compound treatment 168880.0 -7880.0 -0.21 169920.0 292.0 0.01 -0.1434 -0.6801 3176334 HSCI1_000323 CC(C)[C@@]1(C)[C@@H]([C@H](OO)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@@]1(C)[C@@]5(O)C[C@@]3(C)[C@@]6(O)CCC(=C)[C@@H](O)[C@]46O5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J15 compound treatment 179720.0 2960.0 0.08 182560.0 12900.0 0.35 0.3036 0.8458 3054966 HSCI1_000324 C[C@@H]1CNCCCN1S(=O)(=O)c2cccc3cncc(C)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J16 compound treatment 185040.0 8280.0 0.22 188280.0 18700.0 0.5 0.5137 0.9316 3176335 HSCI1_000325 CN1CCN(CCCC(=O)O[C@H]2[C@@H](O)[C@H]3C(C)(C)CC[C@H](O)[C@]3(C)[C@@]4(O)C(=O)C[C@@](C)(O[C@]24C)C=C)CC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J17 compound treatment 35720.0 -141000.0 -3.77 33160.0 -136000.0 -3.69 -5.28 -0.9999 1049343 HSCI1_000326 CCC(C)C1NC(=O)C(NC(=O)c2c(N)c(=O)c(C)c3oc4c(C)ccc(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J18 compound treatment 166640.0 -10100.0 -0.27 163080.0 -6550.0 -0.18 -0.3167 -0.979 3054969 HSCI1_000327 C[C@@]12CCC(=O)C=C2CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@@]4(O)C[C@H](O)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J19 mock treatment 164920.0 -11800.0 -0.32 160480.0 -9150.0 -0.25 -0.399 -0.9926 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J20 mock treatment 157720.0 -19000.0 -0.51 167920.0 -1710.0 -0.05 -0.3928 -0.7682 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J21 mock treatment 175320.0 -1440.0 -0.04 162040.0 -7590.0 -0.21 -0.1724 -0.8251 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J22 mock treatment 162200.0 -14600.0 -0.39 161640.0 -7990.0 -0.22 -0.4283 -0.9615 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J23 compound treatment 129680.0 -47100.0 -1.26 124400.0 -45200.0 -1.22 -1.7562 -0.9999 3054970 HSCI1_000328 NC(=NCCSSCCN=C(N)N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 J24 mock treatment 172080.0 -4680.0 -0.13 179200.0 9570.0 0.26 0.0948 0.3293 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K01 mock treatment 191040.0 14300.0 0.38 158160.0 -11500.0 -0.31 0.0506 0.1028 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K02 compound treatment 107400.0 -69400.0 -1.86 108800.0 -60800.0 -1.65 -2.4763 -0.9982 637 HSCI1_000329 C/C(=C(\C#N)/C(=O)Nc1ccc(OC(F)(F)F)cc1)/O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K03 compound treatment 154240.0 -22500.0 -0.6 64760.0 -105000.0 -2.84 -2.4334 -0.8385 391 HSCI1_000330 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K04 compound treatment 10360.0 -166000.0 -4.45 6640.0 -163000.0 -4.41 -6.2674 -1.0 3055003 HSCI1_000331 O=C1c2ccccc2-[n+]3ccc4c5ccccc5[nH]c4c13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K05 compound treatment 11840.0 -165000.0 -4.41 7800.0 -162000.0 -4.38 -6.2172 -1.0 3055004 HSCI1_000332 Fc1ccc(cc1)C(=O)/C=C/2\C(=O)Nc3ccc(Br)cc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K06 compound treatment 11400.0 -165000.0 -4.42 10320.0 -159000.0 -4.31 -6.1773 -0.9999 3176336 HSCI1_000333 CC(C)(C)C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c3ccccc32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K07 mock treatment 164160.0 -12600.0 -0.34 161280.0 -8350.0 -0.23 -0.3981 -0.9811 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K08 mock treatment 164600.0 -12200.0 -0.33 157640.0 -12000.0 -0.32 -0.4594 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K09 mock treatment 160200.0 -16600.0 -0.44 181800.0 12200.0 0.33 -0.0802 -0.1452 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K10 mock treatment 180000.0 3240.0 0.09 155080.0 -14500.0 -0.39 -0.2172 -0.5385 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K11 compound treatment 69920.0 -107000.0 -2.86 78800.0 -90800.0 -2.46 -3.7595 -0.9972 3055006 HSCI1_000334 COc1cccc(c1)c2cc(NCc3ccc4OCOc4c3)nc(N)n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K12 compound treatment 173880.0 -2880.0 -0.08 173120.0 3490.0 0.09 0.0124 0.1019 3176337 HSCI1_000335 COc1ccc(cc1)c2cnc3c(cnn3c2)c4ccsc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K13 compound treatment 68600.0 -108000.0 -2.89 78440.0 -91200.0 -2.47 -3.7913 -0.9969 3055009 HSCI1_000336 CC1=C(O)C(=O)[C@H]2O[C@H]2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K14 compound treatment 156720.0 -20000.0 -0.54 161720.0 -7910.0 -0.21 -0.5304 -0.919 1709 HSCI1_000337 NCCCC(O)(P(=O)(O)O)P(=O)(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K15 mock treatment 175480.0 -1280.0 -0.03 170880.0 1250.0 0.03 -2.0E-4 -0.0041 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K16 mock treatment 176720.0 -37.6 0.0 142640.0 -27000.0 -0.73 -0.5173 -0.7081 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K17 compound treatment 13760.0 -163000.0 -4.36 12240.0 -157000.0 -4.26 -6.0959 -0.9999 3176338 HSCI1_000338 CCCCCCCCCCCCCCCCOCC(COCC(F)(F)F)OP(=O)(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K18 compound treatment 142960.0 -33800.0 -0.9 162040.0 -7590.0 -0.21 -0.7845 -0.8462 1932 HSCI1_000339 OP(=O)(O)Oc1cccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K19 compound treatment 215000.0 38200.0 1.02 195840.0 26200.0 0.71 1.2251 0.984 95 HSCI1_000340 CCCCCC(O)/C=C/C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K20 compound treatment 13480.0 -163000.0 -4.37 12880.0 -157000.0 -4.24 -6.0889 -0.9999 3176339 HSCI1_000341 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)C[C@H](O)C3=C)\CCC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K21 mock treatment 173320.0 -3440.0 -0.09 161040.0 -8590.0 -0.23 -0.2294 -0.9176 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K22 mock treatment 177760.0 1000.0 0.03 160680.0 -8950.0 -0.24 -0.1523 -0.625 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K23 mock treatment 159040.0 -17700.0 -0.47 197760.0 28100.0 0.76 0.2034 0.2268 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 K24 mock treatment 179360.0 2600.0 0.07 158480.0 -11100.0 -0.3 -0.1642 -0.5301 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L01 mock treatment 162000.0 -14800.0 -0.39 149200.0 -20400.0 -0.55 -0.6702 -0.9863 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L02 compound treatment 124240.0 -52500.0 -1.4 11200.0 -158000.0 -4.29 -4.0261 -0.8921 594 HSCI1_000342 Cc1nc2sccn2c(=O)c1CCN3CCC(=C(c4ccccc4)c5ccc(F)cc5)CC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L03 compound treatment 10320.0 -166000.0 -4.45 7520.0 -162000.0 -4.39 -6.2513 -1.0 581 HSCI1_000343 Cn1cc(C2=C(C(=O)NC2=O)c3c4CC(CN)CCn4c5ccccc35)c6ccccc16 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L04 compound treatment 157640.0 -19100.0 -0.51 125640.0 -44000.0 -1.19 -1.2037 -0.9287 1002019 HSCI1_000344 COc1ccc2C3CC[C@]4(C)[C@H](CCC4C3CCc2c1)NCCCCCCN5C(=O)C=CC5=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L05 compound treatment 33680.0 -143000.0 -3.83 21360.0 -148000.0 -4.01 -5.5445 -0.9997 3055016 HSCI1_000345 COc1cc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(Oc5ccccc5)cc4)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L06 compound treatment 99120.0 -77600.0 -2.08 75680.0 -93900.0 -2.54 -3.2669 -0.9949 2348 HSCI1_000346 COc1ccc2C3CC[C@]4(C)[C@H](CCC4C3CCc2c1)NCCCCCCN5C(=O)CCC5=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L07 mock treatment 158200.0 -18600.0 -0.5 154600.0 -15000.0 -0.41 -0.6387 -0.9951 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L08 mock treatment 185440.0 8680.0 0.23 153880.0 -15700.0 -0.43 -0.1372 -0.2827 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L09 mock treatment 190560.0 13800.0 0.37 162400.0 -7230.0 -0.2 0.1227 0.2936 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L10 mock treatment 197200.0 20400.0 0.55 161560.0 -8070.0 -0.22 0.2322 0.3944 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L11 compound treatment 27120.0 -150000.0 -4.0 31680.0 -138000.0 -3.73 -5.471 -0.9994 582 HSCI1_000347 CN(C)CC1CCn2c(C1)c(C3=C(C(=O)NC3=O)c4cn(C)c5ccccc45)c6ccccc26 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L12 compound treatment 20840.0 -156000.0 -4.17 15800.0 -154000.0 -4.16 -5.8938 -1.0 595 HSCI1_000348 Fc1ccc(cc1)C(=C2CCN(CCn3c(=O)c4ccccc4[nH]c3=S)CC2)c5ccc(F)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L13 compound treatment 168920.0 -7840.0 -0.21 165760.0 -3870.0 -0.1 -0.2223 -0.9486 3176385 HSCI1_000349 NCC1OC(OC2C(N)CC(N)C(O)C2O[C@@H]3OC[C@H](COCC4OCC(O)C(O)C4N)[C@@H]3O)C(N)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L14 compound treatment 151120.0 -25600.0 -0.69 165400.0 -4230.0 -0.11 -0.5659 -0.8139 3055065 HSCI1_000350 Nc1ncn([C@@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L15 mock treatment 181400.0 4640.0 0.12 163080.0 -6550.0 -0.18 -0.0375 -0.1734 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L16 mock treatment 162520.0 -14200.0 -0.38 153320.0 -16300.0 -0.44 -0.5815 -0.9973 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L17 compound treatment 188760.0 12000.0 0.32 176600.0 6970.0 0.19 0.3605 0.9679 372 HSCI1_000351 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L18 compound treatment 148720.0 -28000.0 -0.75 161000.0 -8630.0 -0.23 -0.6955 -0.8854 1367 HSCI1_000352 Cc1cc(O)ccc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L19 compound treatment 12920.0 -164000.0 -4.38 12240.0 -157000.0 -4.26 -6.1118 -0.9999 3055069 HSCI1_000353 CC/C(=C(\c1ccc(O)cc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L20 compound treatment 146360.0 -30400.0 -0.81 146160.0 -23500.0 -0.64 -1.0242 -0.9926 2237 HSCI1_000354 FS(=O)(=O)Cc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L21 mock treatment 165240.0 -11500.0 -0.31 148560.0 -21100.0 -0.57 -0.6212 -0.9582 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L22 mock treatment 153280.0 -23500.0 -0.63 171840.0 2210.0 0.06 -0.4017 -0.6368 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L23 mock treatment 163280.0 -13500.0 -0.36 144160.0 -25500.0 -0.69 -0.7425 -0.9543 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 L24 mock treatment 159520.0 -17200.0 -0.46 152400.0 -17200.0 -0.47 -0.6558 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M01 mock treatment 178880.0 2120.0 0.06 164520.0 -5110.0 -0.14 -0.0576 -0.3856 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M02 compound treatment 151760.0 -25000.0 -0.67 143200.0 -26400.0 -0.72 -0.9787 -0.9994 1900 HSCI1_000355 COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M03 compound treatment 139000.0 -37800.0 -1.01 88800.0 -80800.0 -2.19 -2.2615 -0.9383 3055072 HSCI1_000356 Cn1cc(/C=C/2\C(=O)Nc3ccc(cc23)S(=O)(=O)N)c4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M04 compound treatment 34240.0 -143000.0 -3.81 24920.0 -145000.0 -3.92 -5.4658 -0.9999 292 HSCI1_000357 O=C1NCc2c1c3c4ccccc4[nH]c3c5[nH]c6ccccc6c25 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M05 compound treatment 134720.0 -42000.0 -1.12 138560.0 -31100.0 -0.84 -1.3898 -0.9898 907290 HSCI1_000358 CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](O)[C@@]3(C)O[C@](C)(CC(=O)[C@@]32O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M06 compound treatment 167160.0 -9600.0 -0.26 161840.0 -7790.0 -0.21 -0.3306 -0.9952 3055076 HSCI1_000359 NS(=O)(=O)c1ccc(N/C=C/2\C(=O)Nc3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M07 compound treatment 144280.0 -32500.0 -0.87 139160.0 -30500.0 -0.82 -1.1975 -0.9997 3055122 HSCI1_000360 OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c5cccc1c52 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M08 compound treatment 53720.0 -123000.0 -3.29 50880.0 -119000.0 -3.21 -4.6004 -0.9999 3176387 HSCI1_000361 Nc1cccc(c1)c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M09 mock treatment 198520.0 21800.0 0.58 169560.0 -67.9 0.0 0.4103 0.7049 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M10 mock treatment 163560.0 -13200.0 -0.35 149240.0 -20400.0 -0.55 -0.6399 -0.9767 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M11 mock treatment 166360.0 -10400.0 -0.28 157000.0 -12600.0 -0.34 -0.4384 -0.9948 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M12 mock treatment 184760.0 8000.0 0.21 177040.0 7410.0 0.2 0.2933 0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M13 mock treatment 203360.0 26600.0 0.71 176880.0 7250.0 0.2 0.642 0.8697 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M14 mock treatment 212200.0 35400.0 0.95 155800.0 -13800.0 -0.37 0.4057 0.398 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M15 compound treatment 192680.0 15900.0 0.43 165720.0 -3910.0 -0.11 0.2264 0.5158 2796 HSCI1_000362 CCCCCCCC/C=C\CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M16 compound treatment 14040.0 -163000.0 -4.35 11560.0 -158000.0 -4.28 -6.1036 -1.0 3176388 HSCI1_000363 COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@@H]2c3cc4OCOc4cc3CCN5CCC[C@]25C=C1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M17 compound treatment 59680.0 -117000.0 -3.13 73120.0 -96500.0 -2.61 -4.0619 -0.9959 1000076 HSCI1_000364 CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M18 compound treatment 187720.0 11000.0 0.29 142000.0 -27600.0 -0.75 -0.3215 -0.4002 2058 HSCI1_000365 OC(=O)C1C(C2CCC1O2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M19 compound treatment 157840.0 -18900.0 -0.51 156720.0 -12900.0 -0.35 -0.6049 -0.9837 1000072 HSCI1_000366 CC(C)OP(=O)(F)OC(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M20 compound treatment 11160.0 -166000.0 -4.43 10120.0 -160000.0 -4.32 -6.1856 -0.9999 3176389 HSCI1_000367 CC(=O)O[C@@H]1CC2[C@@]3(C)CCCC(C)(C)C3CC[C@@]2(C)C4CC=C(C=O)[C@H](C=O)[C@@]14C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M21 compound treatment 199400.0 22600.0 0.61 202600.0 33000.0 0.89 1.0595 0.9821 3176390 HSCI1_000368 CCCC(=O)OC1C(OC2COP(O)(O)OC12)n3cnc4c(=O)[nH]c(NOC(=C)CC)nc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M22 compound treatment 85320.0 -91400.0 -2.45 99520.0 -70100.0 -1.9 -3.0716 -0.9921 3055129 HSCI1_000369 CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@@]21C)c5ccc(cc5)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M23 mock treatment 202200.0 25400.0 0.68 165240.0 -4390.0 -0.12 0.3972 0.575 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 M24 mock treatment 163640.0 -13100.0 -0.35 170520.0 892.0 0.02 -0.231 -0.6569 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N01 mock treatment 193760.0 17000.0 0.45 176240.0 6610.0 0.18 0.4482 0.917 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N02 compound treatment 116720.0 -60000.0 -1.61 129120.0 -40500.0 -1.1 -1.911 -0.9827 600 HSCI1_000370 COC(=O)/C=C/c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N03 compound treatment 40640.0 -136000.0 -3.64 8280.0 -161000.0 -4.37 -5.6633 -0.9959 630 HSCI1_000371 COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C/C=C/c3ccc(Cl)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N04 compound treatment 8760.0 -168000.0 -4.49 7000.0 -163000.0 -4.4 -6.2908 -0.9999 2283 HSCI1_000372 CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N05 compound treatment 146280.0 -30500.0 -0.82 140960.0 -28700.0 -0.78 -1.1253 -0.9997 629 HSCI1_000373 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2CN(C)C/C=C/c3ccc(Cl)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N06 compound treatment 182840.0 6080.0 0.16 176760.0 7130.0 0.19 0.2516 0.9964 1884 HSCI1_000374 Cc1ccnc(N)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N07 compound treatment 12120.0 -165000.0 -4.4 9840.0 -160000.0 -4.33 -6.1728 -1.0 1918023 HSCI1_000375 CC[n+]1c(/C=C/N(C)c2ccccc2)n(c3ccccc3)c4ccc(cc14)c5nc6ccccc6s5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N08 compound treatment 183080.0 6320.0 0.17 151200.0 -18400.0 -0.5 -0.2332 -0.4427 2344 HSCI1_000376 FC(F)(F)C(=O)CC(=O)c1cccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N09 mock treatment 180320.0 3560.0 0.1 154960.0 -14700.0 -0.4 -0.2134 -0.5226 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N10 mock treatment 188600.0 11800.0 0.32 163440.0 -6190.0 -0.17 0.1055 0.2945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N11 mock treatment 165040.0 -11700.0 -0.31 190280.0 20700.0 0.56 0.1737 0.271 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N12 mock treatment 163680.0 -13100.0 -0.35 175880.0 6250.0 0.17 -0.1277 -0.3285 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N13 mock treatment 172640.0 -4120.0 -0.11 195480.0 25900.0 0.7 0.417 0.5886 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N14 mock treatment 165440.0 -11300.0 -0.3 176680.0 7050.0 0.19 -0.0791 -0.2209 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N15 compound treatment 15040.0 -162000.0 -4.33 12920.0 -157000.0 -4.24 -6.0587 -1.0 1000048 HSCI1_000377 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N16 compound treatment 179480.0 2720.0 0.07 154680.0 -14900.0 -0.4 -0.2347 -0.5707 2187 HSCI1_000378 O=C(NC1CCCCC1)NC2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N17 compound treatment 165800.0 -11000.0 -0.29 171080.0 1450.0 0.04 -0.1795 -0.6068 2083 HSCI1_000379 CC(CCC(=O)NCC(=O)O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N18 compound treatment 172480.0 -4280.0 -0.11 162760.0 -6870.0 -0.19 -0.2124 -0.9728 1934 HSCI1_000380 NNC(=N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N19 compound treatment 163840.0 -12900.0 -0.35 157120.0 -12500.0 -0.34 -0.4838 -0.9999 30 HSCI1_000381 COC(=O)C1=C(C)NC(=C(C1c2ccccc2C(F)(F)F)[N+](=O)[O-])C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N20 compound treatment 11160.0 -166000.0 -4.43 8640.0 -161000.0 -4.36 -6.214 -1.0 420 HSCI1_000382 CCN1C(=O)C=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N21 compound treatment 168760.0 -8000.0 -0.21 173160.0 3530.0 0.1 -0.0837 -0.357 3054850 HSCI1_000383 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N22 compound treatment 91640.0 -85100.0 -2.28 93000.0 -76600.0 -2.07 -3.0768 -0.9989 2003 HSCI1_000384 CNC1CCc2cc(OC)c(OC)c(OC)c2-c3ccc(OC)c(=O)cc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N23 mock treatment 159240.0 -17500.0 -0.47 167920.0 -1710.0 -0.05 -0.364 -0.7731 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 N24 mock treatment 167440.0 -9320.0 -0.25 180160.0 10500.0 0.29 0.0254 0.067 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O01 mock treatment 195720.0 19000.0 0.51 151680.0 -17900.0 -0.49 0.0151 0.0215 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O02 mock treatment 171480.0 -5280.0 -0.14 181560.0 11900.0 0.32 0.1286 0.3648 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O03 compound treatment 9960.0 -167000.0 -4.46 8280.0 -161000.0 -4.37 -6.2436 -0.9999 3054852 HSCI1_000385 O=C/1Nc2ccc(cc2\C1=C\c3ccc[nH]3)c4cccnc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O04 compound treatment 111800.0 -65000.0 -1.74 110960.0 -58700.0 -1.59 -2.3517 -0.999 3176393 HSCI1_000386 Cn1nc(N)c2cn(C3OC(CO)C(O)C3O)c4ncnc1c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O05 compound treatment 13720.0 -163000.0 -4.36 7960.0 -162000.0 -4.38 -6.1786 -1.0 3176394 HSCI1_000387 C1CCC(CC1)Nc2nc(Nc3ccc(cc3)N4CCOCC4)nc5[nH]cnc25 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O06 compound treatment 56200.0 -121000.0 -3.22 49400.0 -120000.0 -3.25 -4.5818 -1.0 575 HSCI1_000388 O=C1NC(=O)C(=C1c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O07 compound treatment 36600.0 -140000.0 -3.75 44360.0 -125000.0 -3.39 -5.049 -0.9987 3176395 HSCI1_000389 CCCCN1C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@@H](N2C1=O)c5ccc(OC)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O08 compound treatment 140840.0 -35900.0 -0.96 51000.0 -119000.0 -3.21 -2.9503 -0.8801 2116778 HSCI1_000390 CCOC(=O)c1cnc2oc3ccc(O)cc3c2c1c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O09 compound treatment 27360.0 -149000.0 -4.0 16000.0 -154000.0 -4.16 -5.7667 -0.9998 3176396 HSCI1_000391 CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c3ncn(C(C)C)c3n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O10 compound treatment 137920.0 -38800.0 -1.04 114360.0 -55300.0 -1.5 -1.7926 -0.9841 676 HSCI1_000392 COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O11 mock treatment 183920.0 7160.0 0.19 169360.0 -268.0 -0.01 0.1303 0.6799 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O12 mock treatment 165000.0 -11800.0 -0.31 166280.0 -3350.0 -0.09 -0.2865 -0.8753 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O13 mock treatment 161360.0 -15400.0 -0.41 151880.0 -17700.0 -0.48 -0.631 -0.9971 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O14 mock treatment 165920.0 -10800.0 -0.29 147880.0 -21700.0 -0.59 -0.6213 -0.9467 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O15 compound treatment 164320.0 -12400.0 -0.33 155920.0 -13700.0 -0.37 -0.4977 -0.9985 1398 HSCI1_000393 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O16 compound treatment 17080.0 -160000.0 -4.27 98920.0 -70700.0 -1.91 -4.3738 -0.9345 2060355 HSCI1_000394 CC1=C(C=C)/C(=C/c2[nH]c(Cc3[nH]c(\C=C\4/NC(=O)C(=C4C)C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)/NC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O17 compound treatment 170880.0 -5880.0 -0.16 157320.0 -12300.0 -0.33 -0.3468 -0.9412 1929 HSCI1_000395 Nc1cccc2c(=O)[nH]ccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O18 compound treatment 162960.0 -13800.0 -0.37 143920.0 -25700.0 -0.7 -0.7531 -0.956 2286 HSCI1_000396 CCSC(=N)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O19 compound treatment 199400.0 22600.0 0.61 161120.0 -8510.0 -0.23 0.2654 0.4096 23 HSCI1_000397 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O20 compound treatment 10640.0 -166000.0 -4.44 8520.0 -161000.0 -4.36 -6.2261 -1.0 3054913 HSCI1_000398 Cc1ccc(cc1)S(=O)(=O)N[C@H](Cc2ccccc2)C(=O)CCl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O21 compound treatment 10480.0 -166000.0 -4.45 9280.0 -160000.0 -4.34 -6.2146 -0.9999 3176397 HSCI1_000399 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C/3\C[C@@H](O)C[C@H](O)C3=C)/CCC[C@@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O22 compound treatment 183480.0 6720.0 0.18 154120.0 -15500.0 -0.42 -0.1697 -0.3716 988 HSCI1_000400 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O23 mock treatment 166040.0 -10700.0 -0.29 159080.0 -10500.0 -0.29 -0.4046 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 O24 mock treatment 186120.0 9360.0 0.25 150040.0 -19600.0 -0.53 -0.1979 -0.3374 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P01 mock treatment 187880.0 11100.0 0.3 168120.0 -1510.0 -0.04 0.1815 0.6044 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P02 mock treatment 172080.0 -4680.0 -0.13 169000.0 -628.0 -0.02 -0.1005 -0.7959 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P03 mock treatment 171080.0 -5680.0 -0.15 153320.0 -16300.0 -0.44 -0.4196 -0.8987 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P04 mock treatment 189560.0 12800.0 0.34 160200.0 -9430.0 -0.26 0.0617 0.1444 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P05 mock treatment 181400.0 4640.0 0.12 159520.0 -10100.0 -0.27 -0.1057 -0.3517 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P06 mock treatment 168680.0 -8080.0 -0.22 144440.0 -25200.0 -0.68 -0.635 -0.8877 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P07 mock treatment 172880.0 -3880.0 -0.1 140160.0 -29500.0 -0.8 -0.6375 -0.7924 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P08 mock treatment 186240.0 9480.0 0.25 137160.0 -32500.0 -0.88 -0.4422 -0.4833 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P09 mock treatment 161280.0 -15500.0 -0.41 140440.0 -29200.0 -0.79 -0.8515 -0.9545 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P10 mock treatment 173760.0 -3000.0 -0.08 145920.0 -23700.0 -0.64 -0.5105 -0.7893 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P11 mock treatment 182640.0 5880.0 0.16 145360.0 -24300.0 -0.66 -0.3533 -0.523 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P12 mock treatment 172320.0 -4440.0 -0.12 168280.0 -1350.0 -0.04 -0.1097 -0.8837 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P13 mock treatment 162800.0 -14000.0 -0.37 153800.0 -15800.0 -0.43 -0.567 -0.9976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P14 mock treatment 167200.0 -9560.0 -0.26 149800.0 -19800.0 -0.54 -0.5603 -0.9424 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P15 mock treatment 167040.0 -9720.0 -0.26 151360.0 -18300.0 -0.49 -0.5335 -0.9549 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P16 mock treatment 161000.0 -15800.0 -0.42 141600.0 -28000.0 -0.76 -0.8346 -0.9615 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P17 mock treatment 181320.0 4560.0 0.12 185360.0 15700.0 0.43 0.3875 0.8745 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P18 mock treatment 168560.0 -8200.0 -0.22 129960.0 -39700.0 -1.07 -0.9144 -0.8343 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P19 mock treatment 171880.0 -4880.0 -0.13 144760.0 -24900.0 -0.67 -0.5683 -0.8287 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P20 mock treatment 144520.0 -32200.0 -0.86 148640.0 -21000.0 -0.57 -1.0115 -0.9795 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P21 mock treatment 170120.0 -6640.0 -0.18 149920.0 -19700.0 -0.53 -0.5028 -0.8942 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P22 mock treatment 143600.0 -33200.0 -0.89 154000.0 -15600.0 -0.42 -0.9263 -0.9427 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P23 mock treatment 154000.0 -22800.0 -0.61 150360.0 -19300.0 -0.52 -0.7993 -0.997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2105 P24 mock treatment 159600.0 -17200.0 -0.46 148600.0 -21000.0 -0.57 -0.7271 -0.9943 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A01 compound treatment 209080.0 68200.0 1.83 198000.0 57000.0 1.54 2.382 0.9965 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A02 compound treatment 190520.0 49700.0 1.33 193040.0 52100.0 1.41 1.936 0.9996 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A03 compound treatment 184960.0 44100.0 1.18 190480.0 49500.0 1.34 1.7818 0.998 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A04 compound treatment 185080.0 44200.0 1.18 194240.0 53300.0 1.44 1.856 0.9952 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A05 compound treatment 169200.0 28400.0 0.76 192440.0 51500.0 1.39 1.5212 0.9592 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A06 compound treatment 182720.0 41900.0 1.12 187080.0 46100.0 1.25 1.6743 0.9985 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A07 compound treatment 171840.0 31000.0 0.83 180560.0 39600.0 1.07 1.3437 0.992 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A08 compound treatment 155560.0 14700.0 0.39 171880.0 30900.0 0.84 0.8697 0.9409 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A09 compound treatment 143720.0 2880.0 0.08 186280.0 45300.0 1.23 0.9214 0.75 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A10 compound treatment 196160.0 55300.0 1.48 186360.0 45400.0 1.23 1.9148 0.9957 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A11 compound treatment 133240.0 -7610.0 -0.2 192240.0 51300.0 1.39 0.8372 0.5971 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A12 compound treatment 178240.0 37400.0 1.0 190800.0 49800.0 1.35 1.6608 0.9892 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A13 mock treatment 178160.0 37300.0 1.0 193160.0 52200.0 1.41 1.7045 0.9856 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A14 mock treatment 163080.0 22200.0 0.59 191960.0 51000.0 1.38 1.3963 0.9292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A15 compound treatment 195080.0 54200.0 1.45 169360.0 28400.0 0.77 1.5689 0.9558 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A16 compound treatment 183240.0 42400.0 1.13 183400.0 42400.0 1.15 1.6137 1.0 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A17 compound treatment 190040.0 49200.0 1.32 202560.0 61600.0 1.67 2.1091 0.9931 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A18 compound treatment 199400.0 58600.0 1.57 169880.0 28900.0 0.78 1.6606 0.9485 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A19 compound treatment 204520.0 63700.0 1.7 198000.0 57000.0 1.54 2.2957 0.9988 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A20 compound treatment 177400.0 36600.0 0.98 189880.0 48900.0 1.32 1.6273 0.9889 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A21 compound treatment 235680.0 94800.0 2.54 233960.0 93000.0 2.52 3.5735 1.0 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A22 compound treatment 197120.0 56300.0 1.51 201520.0 60500.0 1.64 2.2231 0.9991 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A23 compound treatment 219400.0 78600.0 2.1 217280.0 76300.0 2.07 2.9462 1.0 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 A24 compound treatment 195960.0 55100.0 1.47 181960.0 41000.0 1.11 1.8268 0.9902 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B01 compound treatment 197880.0 57000.0 1.53 233720.0 92700.0 2.51 2.8539 0.9715 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B02 compound treatment 189080.0 48200.0 1.29 211280.0 70300.0 1.9 2.2579 0.9821 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B03 compound treatment 171200.0 30400.0 0.81 182080.0 41100.0 1.11 1.3607 0.988 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B04 compound treatment 147040.0 6200.0 0.17 180800.0 39800.0 1.08 0.8793 0.8064 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B05 compound treatment 162440.0 21600.0 0.58 155800.0 14800.0 0.4 0.692 0.9841 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B06 compound treatment 126360.0 -14500.0 -0.39 181480.0 40500.0 1.1 0.5011 0.431 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B07 compound treatment 137800.0 -3050.0 -0.08 155920.0 14900.0 0.4 0.2282 0.5535 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B08 compound treatment 141480.0 635.0 0.02 166760.0 25800.0 0.7 0.5053 0.7241 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B09 compound treatment 136720.0 -4130.0 -0.11 148680.0 7690.0 0.21 0.0692 0.2936 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B10 compound treatment 122760.0 -18100.0 -0.48 139880.0 -1110.0 -0.03 -0.3633 -0.7496 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B11 compound treatment 145160.0 4320.0 0.12 138880.0 -2110.0 -0.06 0.0412 0.3201 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B12 compound treatment 137680.0 -3170.0 -0.08 163480.0 22500.0 0.61 0.3707 0.603 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B13 mock treatment 130720.0 -10100.0 -0.27 136280.0 -4710.0 -0.13 -0.2817 -0.941 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B14 mock treatment 137960.0 -2890.0 -0.08 144360.0 3370.0 0.09 0.0099 0.0832 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B15 compound treatment 132480.0 -8370.0 -0.22 151160.0 10200.0 0.28 0.0365 0.1028 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B16 compound treatment 111240.0 -29600.0 -0.79 165400.0 24400.0 0.66 -0.0927 -0.0898 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B17 compound treatment 144240.0 3400.0 0.09 162000.0 21000.0 0.57 0.4664 0.8097 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B18 compound treatment 123400.0 -17400.0 -0.47 139560.0 -1430.0 -0.04 -0.3573 -0.7631 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B19 compound treatment 139680.0 -1170.0 -0.03 150480.0 9490.0 0.26 0.1596 0.6168 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B20 compound treatment 142920.0 2080.0 0.06 144720.0 3730.0 0.1 0.1107 0.9603 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B21 compound treatment 158600.0 17800.0 0.47 150640.0 9650.0 0.26 0.5206 0.9604 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B22 compound treatment 149760.0 8920.0 0.24 158960.0 18000.0 0.49 0.5126 0.9462 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B23 compound treatment 155280.0 14400.0 0.39 188920.0 47900.0 1.3 1.1906 0.8794 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 B24 compound treatment 217960.0 77100.0 2.06 222240.0 81300.0 2.2 3.014 0.9995 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C01 compound treatment 122160.0 -18700.0 -0.5 147560.0 6570.0 0.18 -0.2276 -0.4291 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C02 compound treatment 168800.0 28000.0 0.75 207720.0 66700.0 1.81 1.8062 0.9238 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C03 compound treatment 143160.0 2320.0 0.06 159680.0 18700.0 0.51 0.4016 0.7878 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C04 compound treatment 140560.0 -285.0 -0.01 149880.0 8890.0 0.24 0.1648 0.6844 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C05 compound treatment 153240.0 12400.0 0.33 174240.0 33300.0 0.9 0.871 0.9079 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C06 compound treatment 140080.0 -765.0 -0.02 158080.0 17100.0 0.46 0.3127 0.6752 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C07 compound treatment 137560.0 -3290.0 -0.09 139480.0 -1510.0 -0.04 -0.091 -0.9394 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C08 compound treatment 128680.0 -12200.0 -0.33 139080.0 -1910.0 -0.05 -0.2667 -0.8093 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C09 compound treatment 124480.0 -16400.0 -0.44 137720.0 -3270.0 -0.09 -0.3721 -0.8332 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C10 compound treatment 130680.0 -10200.0 -0.27 135120.0 -5870.0 -0.16 -0.3046 -0.9673 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C11 mock treatment 127400.0 -13400.0 -0.36 154120.0 13100.0 0.36 -0.003 -0.0058 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C12 mock treatment 145920.0 5080.0 0.14 153680.0 12700.0 0.34 0.3389 0.9175 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C13 compound treatment 141240.0 395.0 0.01 157760.0 16800.0 0.45 0.3285 0.7234 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C14 compound treatment 138480.0 -2370.0 -0.06 142200.0 1210.0 0.03 -0.0216 -0.3028 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C15 mock treatment 143480.0 2640.0 0.07 144440.0 3450.0 0.09 0.1159 0.9904 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C16 mock treatment 134760.0 -6090.0 -0.16 147640.0 6650.0 0.18 0.0122 0.0503 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C17 compound treatment 126360.0 -14500.0 -0.39 146360.0 5370.0 0.15 -0.1712 -0.4136 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C18 compound treatment 146160.0 5320.0 0.14 154200.0 13200.0 0.36 0.3534 0.9183 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C19 compound treatment 140760.0 -85.0 0.0 161280.0 20300.0 0.55 0.3868 0.7042 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C20 compound treatment 136440.0 -4410.0 -0.12 148520.0 7530.0 0.2 0.0608 0.2584 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C21 compound treatment 127720.0 -13100.0 -0.35 163640.0 22700.0 0.61 0.1853 0.2623 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C22 compound treatment 142600.0 1760.0 0.05 152120.0 11100.0 0.3 0.2463 0.8075 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C23 compound treatment 154480.0 13600.0 0.36 147960.0 6970.0 0.19 0.3913 0.953 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 C24 compound treatment 184240.0 43400.0 1.16 185160.0 44200.0 1.2 1.6663 0.9999 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D01 compound treatment 172560.0 31700.0 0.85 160120.0 19100.0 0.52 0.9661 0.972 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D02 compound treatment 28120.0 -113000.0 -3.02 20040.0 -121000.0 -3.27 -4.4475 -0.9992 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D03 compound treatment 195920.0 55100.0 1.47 163560.0 22600.0 0.61 1.4738 0.9241 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D04 compound treatment 166720.0 25900.0 0.69 221640.0 80700.0 2.18 2.0333 0.8877 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D05 compound treatment 204920.0 64100.0 1.71 213600.0 72600.0 1.97 2.6019 0.9977 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D06 compound treatment 109640.0 -31200.0 -0.83 126200.0 -14800.0 -0.4 -0.8733 -0.9434 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D07 compound treatment 170320.0 29500.0 0.79 166720.0 25700.0 0.7 1.0501 0.9981 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D08 compound treatment 188040.0 47200.0 1.26 179360.0 38400.0 1.04 1.6272 0.9953 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D09 compound treatment 131960.0 -8890.0 -0.24 155280.0 14300.0 0.39 0.1055 0.2324 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D10 compound treatment 169960.0 29100.0 0.78 161080.0 20100.0 0.54 0.9353 0.9846 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D11 mock treatment 146160.0 5320.0 0.14 170320.0 29300.0 0.79 0.662 0.8207 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D12 mock treatment 163800.0 23000.0 0.61 175760.0 34800.0 0.94 1.0998 0.9786 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D13 compound treatment 177840.0 37000.0 0.99 161200.0 20200.0 0.55 1.0866 0.961 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D14 compound treatment 162600.0 21800.0 0.58 174080.0 33100.0 0.9 1.0449 0.9782 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D15 mock treatment 150120.0 9280.0 0.25 158600.0 17600.0 0.48 0.5125 0.9537 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D16 mock treatment 148840.0 8000.0 0.21 182760.0 41800.0 1.13 0.9508 0.8262 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D17 compound treatment 153840.0 13000.0 0.35 158480.0 17500.0 0.47 0.5806 0.9884 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D18 compound treatment 149120.0 8280.0 0.22 167880.0 26900.0 0.73 0.6713 0.8822 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D19 compound treatment 154200.0 13400.0 0.36 177440.0 36500.0 0.99 0.9504 0.9056 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D20 compound treatment 142160.0 1320.0 0.04 144280.0 3290.0 0.09 0.0879 0.9174 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D21 compound treatment 174960.0 34100.0 0.91 193720.0 52700.0 1.43 1.6547 0.9766 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D22 compound treatment 172520.0 31700.0 0.85 183560.0 42600.0 1.15 1.414 0.9886 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D23 compound treatment 163920.0 23100.0 0.62 196560.0 55600.0 1.5 1.5002 0.9226 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 D24 compound treatment 117200.0 -23600.0 -0.63 137360.0 -3630.0 -0.1 -0.5167 -0.8073 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E01 mock treatment 195000.0 54200.0 1.45 186440.0 45500.0 1.23 1.8944 0.9967 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E02 mock treatment 134960.0 -5890.0 -0.16 173840.0 32900.0 0.89 0.5175 0.573 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E03 compound treatment 154800.0 14000.0 0.37 160200.0 19200.0 0.52 0.6317 0.9868 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E04 compound treatment 132200.0 -8650.0 -0.23 154600.0 13600.0 0.37 0.097 0.223 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E05 compound treatment 153040.0 12200.0 0.33 164120.0 23100.0 0.63 0.6734 0.9538 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E06 compound treatment 139080.0 -1770.0 -0.05 155200.0 14200.0 0.38 0.2386 0.6157 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E07 compound treatment 134120.0 -6730.0 -0.18 122040.0 -19000.0 -0.51 -0.49 -0.9012 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E08 compound treatment 123280.0 -17600.0 -0.47 140960.0 -30.0 0.0 -0.3328 -0.7083 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E09 mock treatment 128320.0 -12500.0 -0.34 152360.0 11400.0 0.31 -0.0192 -0.0423 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E10 mock treatment 153560.0 12700.0 0.34 149160.0 8170.0 0.22 0.3969 0.9783 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E11 compound treatment 139000.0 -1850.0 -0.05 139080.0 -1910.0 -0.05 -0.0715 -0.9997 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E12 compound treatment 149120.0 8280.0 0.22 158960.0 18000.0 0.49 0.5005 0.9365 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E13 compound treatment 138160.0 -2690.0 -0.07 146240.0 5250.0 0.14 0.0497 0.3122 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E14 compound treatment 205560.0 64700.0 1.73 135240.0 -5750.0 -0.16 1.114 0.6409 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E15 compound treatment 135920.0 -4930.0 -0.13 145520.0 4530.0 0.12 -0.0064 -0.0357 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E16 compound treatment 14720.0 -126000.0 -3.37 16400.0 -125000.0 -3.37 -4.7706 -1.0 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E17 mock treatment 143240.0 2400.0 0.06 144440.0 3450.0 0.09 0.1113 0.9831 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E18 mock treatment 138080.0 -2770.0 -0.07 143720.0 2730.0 0.07 0.0 -4.0E-4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E19 compound treatment 125800.0 -15000.0 -0.4 142000.0 1010.0 0.03 -0.2652 -0.6575 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E20 compound treatment 127920.0 -12900.0 -0.35 142120.0 1130.0 0.03 -0.2228 -0.642 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E21 compound treatment 141920.0 1080.0 0.03 139120.0 -1870.0 -0.05 -0.0155 -0.2656 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E22 compound treatment 143440.0 2600.0 0.07 169520.0 28500.0 0.77 0.5952 0.7676 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E23 compound treatment 169120.0 28300.0 0.76 168960.0 28000.0 0.76 1.0702 1.0 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 E24 compound treatment 191760.0 50900.0 1.36 202560.0 61600.0 1.67 2.1417 0.995 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F01 mock treatment 185320.0 44500.0 1.19 167720.0 26700.0 0.72 1.3529 0.9716 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F02 mock treatment 166280.0 25400.0 0.68 166560.0 25600.0 0.69 0.9706 1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F03 compound treatment 148440.0 7600.0 0.2 143880.0 2890.0 0.08 0.199 0.914 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F04 compound treatment 103120.0 -37700.0 -1.01 122320.0 -18700.0 -0.51 -1.0709 -0.9489 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F05 compound treatment 146480.0 5640.0 0.15 166680.0 25700.0 0.7 0.5984 0.8408 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F06 compound treatment 144440.0 3600.0 0.1 159120.0 18100.0 0.49 0.4151 0.8299 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F07 compound treatment 147360.0 6520.0 0.17 154720.0 13700.0 0.37 0.3861 0.9404 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F08 compound treatment 138200.0 -2650.0 -0.07 146280.0 5290.0 0.14 0.0512 0.3208 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F09 mock treatment 194120.0 53300.0 1.43 142440.0 1450.0 0.04 1.0354 0.7263 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F10 mock treatment 134680.0 -6170.0 -0.16 138440.0 -2550.0 -0.07 -0.1654 -0.9253 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F11 compound treatment 128680.0 -12200.0 -0.33 140320.0 -670.0 -0.02 -0.2429 -0.7454 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F12 compound treatment 144280.0 3440.0 0.09 152560.0 11600.0 0.31 0.2865 0.8776 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F13 compound treatment 138880.0 -1970.0 -0.05 143200.0 2210.0 0.06 0.0051 0.0645 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F14 compound treatment 137440.0 -3410.0 -0.09 157200.0 16200.0 0.44 0.2459 0.5487 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F15 compound treatment 127200.0 -13600.0 -0.36 153760.0 12800.0 0.35 -0.0136 -0.0271 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F16 compound treatment 104000.0 -36800.0 -0.99 107640.0 -33400.0 -0.9 -1.3353 -0.999 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F17 mock treatment 132440.0 -8410.0 -0.22 141080.0 90.0 0.0 -0.1573 -0.6994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F18 mock treatment 125120.0 -15700.0 -0.42 132360.0 -8630.0 -0.23 -0.4626 -0.9615 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F19 compound treatment 146240.0 5400.0 0.14 151920.0 10900.0 0.3 0.3113 0.9455 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F20 compound treatment 135400.0 -5450.0 -0.15 141560.0 570.0 0.02 -0.0921 -0.6287 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F21 compound treatment 155560.0 14700.0 0.39 164120.0 23100.0 0.63 0.7211 0.975 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F22 compound treatment 149760.0 8920.0 0.24 176640.0 35700.0 0.97 0.8511 0.8561 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F23 compound treatment 148800.0 7960.0 0.21 145400.0 4410.0 0.12 0.2349 0.9627 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 F24 compound treatment 183280.0 42400.0 1.14 203080.0 62100.0 1.68 1.9912 0.9817 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G01 compound treatment 200640.0 59800.0 1.6 171440.0 30500.0 0.82 1.7139 0.9525 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G02 compound treatment 29080.0 -112000.0 -2.99 41320.0 -99700.0 -2.7 -4.0219 -0.9987 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G03 mock treatment 136200.0 -4650.0 -0.12 150880.0 9890.0 0.27 0.1015 0.3438 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G04 mock treatment 127440.0 -13400.0 -0.36 149120.0 8130.0 0.22 -0.0979 -0.2327 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G05 compound treatment 149880.0 9040.0 0.24 148600.0 7610.0 0.21 0.3166 0.9968 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G06 compound treatment 121720.0 -19100.0 -0.51 161040.0 20100.0 0.54 0.0221 0.0296 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G07 compound treatment 144560.0 3720.0 0.1 136200.0 -4790.0 -0.13 -0.0214 -0.1312 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G08 compound treatment 113440.0 -27400.0 -0.73 127280.0 -13700.0 -0.37 -0.7808 -0.9503 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G09 compound treatment 132560.0 -8290.0 -0.22 130000.0 -11000.0 -0.3 -0.3671 -0.9895 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G10 compound treatment 122600.0 -18200.0 -0.49 130320.0 -10700.0 -0.29 -0.5493 -0.9687 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G11 compound treatment 126280.0 -14600.0 -0.39 137760.0 -3230.0 -0.09 -0.3373 -0.8448 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G12 compound treatment 131520.0 -9330.0 -0.25 123600.0 -17400.0 -0.47 -0.5093 -0.9559 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G13 compound treatment 124720.0 -16100.0 -0.43 137480.0 -3510.0 -0.1 -0.3722 -0.8427 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G14 compound treatment 115760.0 -25100.0 -0.67 150200.0 9210.0 0.25 -0.2982 -0.4165 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G15 compound treatment 117160.0 -23700.0 -0.63 148040.0 7050.0 0.19 -0.313 -0.4731 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G16 compound treatment 135320.0 -5530.0 -0.15 130440.0 -10600.0 -0.29 -0.3065 -0.953 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G17 compound treatment 131360.0 -9490.0 -0.25 138600.0 -2390.0 -0.06 -0.2252 -0.8599 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G18 compound treatment 116360.0 -24500.0 -0.65 127400.0 -13600.0 -0.37 -0.7233 -0.9628 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G19 mock treatment 137000.0 -3850.0 -0.1 151880.0 10900.0 0.29 0.1357 0.4347 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G20 mock treatment 134600.0 -6250.0 -0.17 132120.0 -8870.0 -0.24 -0.2879 -0.9843 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G21 compound treatment 142200.0 1360.0 0.04 145360.0 4370.0 0.12 0.1093 0.8832 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G22 compound treatment 124400.0 -16400.0 -0.44 151360.0 10400.0 0.28 -0.1125 -0.2156 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G23 compound treatment 131400.0 -9450.0 -0.25 137000.0 -3990.0 -0.11 -0.255 -0.9282 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 G24 compound treatment 183560.0 42700.0 1.14 200240.0 59300.0 1.6 1.9422 0.9862 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H01 compound treatment 182520.0 41700.0 1.11 167000.0 26000.0 0.7 1.2862 0.9755 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H02 compound treatment 145600.0 4760.0 0.13 156400.0 15400.0 0.42 0.3849 0.8826 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H03 mock treatment 151520.0 10700.0 0.29 152240.0 11300.0 0.3 0.4173 0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H04 mock treatment 139760.0 -1090.0 -0.03 148000.0 7010.0 0.19 0.1137 0.5921 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H05 compound treatment 151680.0 10800.0 0.29 156240.0 15300.0 0.41 0.4969 0.985 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H06 compound treatment 137720.0 -3130.0 -0.08 152400.0 11400.0 0.31 0.1593 0.4979 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H07 compound treatment 138480.0 -2370.0 -0.06 138160.0 -2830.0 -0.08 -0.0989 -0.9955 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H08 compound treatment 157320.0 16500.0 0.44 136280.0 -4710.0 -0.13 0.2214 0.4827 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H09 compound treatment 126040.0 -14800.0 -0.4 122720.0 -18300.0 -0.49 -0.6298 -0.9939 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H10 compound treatment 130640.0 -10200.0 -0.27 132960.0 -8030.0 -0.22 -0.3467 -0.9936 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H11 compound treatment 128360.0 -12500.0 -0.33 126560.0 -14400.0 -0.39 -0.5124 -0.997 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H12 compound treatment 125560.0 -15300.0 -0.41 132160.0 -8830.0 -0.24 -0.4581 -0.9673 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H13 compound treatment 134800.0 -6050.0 -0.16 130680.0 -10300.0 -0.28 -0.3117 -0.9663 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H14 compound treatment 120240.0 -20600.0 -0.55 128000.0 -13000.0 -0.35 -0.6384 -0.9764 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H15 compound treatment 130160.0 -10700.0 -0.29 137960.0 -3030.0 -0.08 -0.2601 -0.8747 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H16 compound treatment 127960.0 -12900.0 -0.34 133160.0 -7830.0 -0.21 -0.3936 -0.9727 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H17 compound treatment 129520.0 -11300.0 -0.3 124760.0 -16200.0 -0.44 -0.5249 -0.9835 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H18 compound treatment 129680.0 -11200.0 -0.3 150880.0 9890.0 0.27 -0.0219 -0.0545 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H19 mock treatment 123800.0 -17000.0 -0.46 144480.0 3490.0 0.09 -0.2556 -0.5489 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H20 mock treatment 126680.0 -14200.0 -0.38 135240.0 -5750.0 -0.16 -0.378 -0.9228 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H21 compound treatment 130160.0 -10700.0 -0.29 135880.0 -5110.0 -0.14 -0.2999 -0.9445 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H22 compound treatment 112280.0 -28600.0 -0.76 107760.0 -33200.0 -0.9 -1.1764 -0.9967 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H23 compound treatment 134520.0 -6330.0 -0.17 180840.0 39900.0 1.08 0.6432 0.589 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 H24 compound treatment 183240.0 42400.0 1.13 179120.0 38100.0 1.03 1.5318 0.9989 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I01 compound treatment 203680.0 62800.0 1.68 170840.0 29900.0 0.81 1.7599 0.9437 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I02 compound treatment 150680.0 9840.0 0.26 162440.0 21500.0 0.58 0.5966 0.9359 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I03 compound treatment 143080.0 2240.0 0.06 141920.0 930.0 0.03 0.0601 0.9261 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I04 compound treatment 142040.0 1200.0 0.03 178320.0 37300.0 1.01 0.7372 0.7291 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I05 mock treatment 137280.0 -3570.0 -0.1 158800.0 17800.0 0.48 0.2735 0.5565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I06 mock treatment 128240.0 -12600.0 -0.34 144480.0 3490.0 0.09 -0.1716 -0.4901 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I07 compound treatment 141840.0 995.0 0.03 125080.0 -15900.0 -0.43 -0.2857 -0.6622 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I08 compound treatment 146200.0 5360.0 0.14 132760.0 -8230.0 -0.22 -0.0563 -0.2124 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I09 compound treatment 153840.0 13000.0 0.35 146400.0 5410.0 0.15 0.3494 0.9262 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I10 compound treatment 152680.0 11800.0 0.32 123920.0 -17100.0 -0.46 -0.1029 -0.1837 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I11 compound treatment 156640.0 15800.0 0.42 134760.0 -6230.0 -0.17 0.1795 0.3946 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I12 compound treatment 169240.0 28400.0 0.76 152720.0 11700.0 0.32 0.7616 0.9251 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I13 compound treatment 147640.0 6800.0 0.18 132880.0 -8110.0 -0.22 -0.0267 -0.0938 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I14 compound treatment 148360.0 7520.0 0.2 136800.0 -4190.0 -0.11 0.0619 0.2683 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I15 compound treatment 136440.0 -4410.0 -0.12 129520.0 -11500.0 -0.31 -0.3029 -0.912 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I16 compound treatment 131440.0 -9410.0 -0.25 127800.0 -13200.0 -0.36 -0.4304 -0.9853 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I17 compound treatment 130200.0 -10600.0 -0.28 126760.0 -14200.0 -0.39 -0.4737 -0.9889 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I18 compound treatment 14360.0 -126000.0 -3.38 11840.0 -129000.0 -3.5 -4.8647 -0.9999 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I19 compound treatment 141240.0 395.0 0.01 140880.0 -110.0 0.0 0.0054 0.4888 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I20 compound treatment 123680.0 -17200.0 -0.46 141880.0 890.0 0.02 -0.3076 -0.6691 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I21 mock treatment 137600.0 -3250.0 -0.09 144600.0 3610.0 0.1 0.0077 0.0591 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I22 mock treatment 130000.0 -10800.0 -0.29 192920.0 51900.0 1.41 0.789 0.5496 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I23 compound treatment 164840.0 24000.0 0.64 162200.0 21200.0 0.57 0.8599 0.9985 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 I24 compound treatment 170520.0 29700.0 0.79 159520.0 18500.0 0.5 0.916 0.9755 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J01 compound treatment 194680.0 53800.0 1.44 187120.0 46100.0 1.25 1.9013 0.9975 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J02 compound treatment 153040.0 12200.0 0.33 125880.0 -15100.0 -0.41 -0.0586 -0.112 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J03 compound treatment 138360.0 -2490.0 -0.07 139640.0 -1350.0 -0.04 -0.0728 -0.9603 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J04 compound treatment 134480.0 -6370.0 -0.17 127280.0 -13700.0 -0.37 -0.3828 -0.9375 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J05 mock treatment 144120.0 3280.0 0.09 135160.0 -5830.0 -0.16 -0.0497 -0.2751 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J06 mock treatment 137200.0 -3650.0 -0.1 136760.0 -4230.0 -0.11 -0.1499 -0.9968 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J07 compound treatment 145840.0 5000.0 0.13 131040.0 -9950.0 -0.27 -0.096 -0.3193 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J08 compound treatment 83120.0 -57700.0 -1.54 54320.0 -86700.0 -2.35 -2.751 -0.9794 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J09 compound treatment 129240.0 -11600.0 -0.31 127080.0 -13900.0 -0.38 -0.4858 -0.9954 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J10 compound treatment 119000.0 -21800.0 -0.58 114040.0 -27000.0 -0.73 -0.9291 -0.9939 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J11 compound treatment 130000.0 -10800.0 -0.29 136720.0 -4270.0 -0.12 -0.2869 -0.9186 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J12 compound treatment 120040.0 -20800.0 -0.56 125760.0 -15200.0 -0.41 -0.6851 -0.9891 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J13 compound treatment 135600.0 -5250.0 -0.14 140360.0 -630.0 -0.02 -0.1113 -0.7873 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J14 compound treatment 108440.0 -32400.0 -0.87 95160.0 -45800.0 -1.24 -1.4902 -0.9846 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J15 compound treatment 128280.0 -12600.0 -0.34 136760.0 -4230.0 -0.11 -0.3186 -0.8974 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J16 compound treatment 112280.0 -28600.0 -0.76 107800.0 -33200.0 -0.9 -1.1756 -0.9967 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J17 compound treatment 124120.0 -16700.0 -0.45 126360.0 -14600.0 -0.4 -0.5964 -0.9982 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J18 compound treatment 105800.0 -35000.0 -0.94 106200.0 -34800.0 -0.94 -1.3288 -1.0 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J19 compound treatment 139160.0 -1690.0 -0.05 127400.0 -13600.0 -0.37 -0.292 -0.7878 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J20 compound treatment 143680.0 2840.0 0.08 140120.0 -870.0 -0.02 0.037 0.4655 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J21 mock treatment 150200.0 9360.0 0.25 134800.0 -6190.0 -0.17 0.0584 0.1941 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J22 mock treatment 128560.0 -12300.0 -0.33 133280.0 -7710.0 -0.21 -0.38 -0.976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J23 compound treatment 140800.0 -45.0 0.0 140480.0 -510.0 -0.01 -0.0106 -0.7658 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 J24 compound treatment 68720.0 -72100.0 -1.93 68600.0 -72400.0 -1.96 -2.75 -1.0 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K01 compound treatment 156600.0 15800.0 0.42 122640.0 -18400.0 -0.5 -0.0533 -0.0818 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K02 compound treatment 134040.0 -6810.0 -0.18 149080.0 8090.0 0.22 0.0262 0.0918 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K03 compound treatment 107720.0 -33100.0 -0.89 95400.0 -45600.0 -1.23 -1.4993 -0.9868 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K04 compound treatment 123240.0 -17600.0 -0.47 139280.0 -1710.0 -0.05 -0.3657 -0.7729 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K05 compound treatment 122160.0 -18700.0 -0.5 135000.0 -5990.0 -0.16 -0.4681 -0.8908 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K06 compound treatment 115880.0 -25000.0 -0.67 126440.0 -14600.0 -0.39 -0.7507 -0.9683 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K07 mock treatment 137520.0 -3330.0 -0.09 124400.0 -16600.0 -0.45 -0.3805 -0.831 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K08 mock treatment 135600.0 -5250.0 -0.14 121760.0 -19200.0 -0.52 -0.4673 -0.8667 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K09 compound treatment 129960.0 -10900.0 -0.29 133000.0 -7990.0 -0.22 -0.3588 -0.9893 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K10 compound treatment 23600.0 -117000.0 -3.14 19720.0 -121000.0 -3.28 -4.5391 -0.9997 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K11 compound treatment 131960.0 -8890.0 -0.24 148200.0 7210.0 0.2 -0.03 -0.0976 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K12 compound treatment 143400.0 2560.0 0.07 138760.0 -2230.0 -0.06 0.0056 0.0618 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K13 compound treatment 119680.0 -21200.0 -0.57 114200.0 -26800.0 -0.73 -0.9132 -0.9925 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K14 compound treatment 136840.0 -4010.0 -0.11 118640.0 -22400.0 -0.61 -0.5036 -0.8196 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K15 mock treatment 129040.0 -11800.0 -0.32 136360.0 -4630.0 -0.13 -0.3119 -0.9181 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K16 mock treatment 130360.0 -10500.0 -0.28 117880.0 -23100.0 -0.63 -0.6407 -0.9345 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K17 compound treatment 118920.0 -21900.0 -0.59 117880.0 -23100.0 -0.63 -0.8571 -0.9995 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K18 compound treatment 121640.0 -19200.0 -0.51 128960.0 -12000.0 -0.33 -0.5935 -0.9758 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K19 compound treatment 131160.0 -9690.0 -0.26 124200.0 -16800.0 -0.45 -0.5046 -0.9645 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K20 compound treatment 120920.0 -19900.0 -0.53 131800.0 -9190.0 -0.25 -0.5528 -0.9398 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K21 compound treatment 126880.0 -14000.0 -0.37 135520.0 -5470.0 -0.15 -0.3689 -0.9179 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K22 compound treatment 132920.0 -7930.0 -0.21 137960.0 -3030.0 -0.08 -0.2079 -0.9146 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K23 mock treatment 133240.0 -7610.0 -0.2 158800.0 17800.0 0.48 0.1971 0.3766 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 K24 mock treatment 176720.0 35900.0 0.96 182160.0 41200.0 1.11 1.4667 0.9972 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L01 compound treatment 181520.0 40700.0 1.09 162880.0 21900.0 0.59 1.1884 0.9592 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L02 compound treatment 34200.0 -107000.0 -2.85 35760.0 -105000.0 -2.85 -4.0315 -1.0 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L03 compound treatment 134320.0 -6530.0 -0.17 139640.0 -1350.0 -0.04 -0.1493 -0.837 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L04 compound treatment 101160.0 -39700.0 -1.06 65240.0 -75800.0 -2.05 -2.2007 -0.953 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L05 compound treatment 141480.0 635.0 0.02 135040.0 -5950.0 -0.16 -0.1019 -0.6291 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L06 compound treatment 120040.0 -20800.0 -0.56 118240.0 -22800.0 -0.62 -0.829 -0.9987 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L07 mock treatment 130440.0 -10400.0 -0.28 118240.0 -22800.0 -0.62 -0.6323 -0.9356 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L08 mock treatment 128160.0 -12700.0 -0.34 121080.0 -19900.0 -0.54 -0.6211 -0.9751 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L09 compound treatment 123560.0 -17300.0 -0.46 115640.0 -25400.0 -0.69 -0.8122 -0.9815 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L10 compound treatment 111360.0 -29500.0 -0.79 96840.0 -44200.0 -1.2 -1.4029 -0.9796 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L11 compound treatment 128400.0 -12400.0 -0.33 117600.0 -23400.0 -0.63 -0.6831 -0.9549 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L12 compound treatment 148160.0 7320.0 0.2 139080.0 -1910.0 -0.05 0.1018 0.503 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L13 compound treatment 122840.0 -18000.0 -0.48 116040.0 -25000.0 -0.68 -0.8182 -0.9863 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L14 compound treatment 111640.0 -29200.0 -0.78 101960.0 -39000.0 -1.06 -1.2995 -0.989 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L15 mock treatment 130080.0 -10800.0 -0.29 123240.0 -17800.0 -0.48 -0.5434 -0.97 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L16 mock treatment 131000.0 -9850.0 -0.26 113200.0 -27800.0 -0.75 -0.7182 -0.901 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L17 compound treatment 119920.0 -20900.0 -0.56 118680.0 -22300.0 -0.6 -0.8229 -0.9993 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L18 compound treatment 126760.0 -14100.0 -0.38 123960.0 -17000.0 -0.46 -0.5924 -0.995 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L19 compound treatment 128000.0 -12800.0 -0.34 132120.0 -8870.0 -0.24 -0.4128 -0.9847 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L20 compound treatment 111760.0 -29100.0 -0.78 74480.0 -66500.0 -1.8 -1.8233 -0.9296 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L21 compound treatment 130840.0 -10000.0 -0.27 130560.0 -10400.0 -0.28 -0.3889 -0.9996 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L22 compound treatment 74160.0 -66700.0 -1.78 59520.0 -81500.0 -2.21 -2.8209 -0.9945 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L23 mock treatment 126600.0 -14200.0 -0.38 146720.0 5730.0 0.16 -0.1597 -0.3883 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 L24 mock treatment 175880.0 35000.0 0.94 180920.0 39900.0 1.08 1.427 0.9975 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M01 compound treatment 198720.0 57900.0 1.55 173400.0 32400.0 0.88 1.7151 0.9638 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M02 compound treatment 156320.0 15500.0 0.41 151560.0 10600.0 0.29 0.495 0.9837 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M03 compound treatment 141560.0 715.0 0.02 128120.0 -12900.0 -0.35 -0.2328 -0.6673 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M04 compound treatment 124320.0 -16500.0 -0.44 154160.0 13200.0 0.36 -0.0604 -0.1064 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M05 compound treatment 139120.0 -1730.0 -0.05 124080.0 -16900.0 -0.46 -0.3563 -0.7745 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M06 compound treatment 129760.0 -11100.0 -0.3 135920.0 -5070.0 -0.14 -0.3067 -0.9387 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M07 compound treatment 138280.0 -2570.0 -0.07 125640.0 -15400.0 -0.42 -0.3424 -0.8128 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M08 compound treatment 123960.0 -16900.0 -0.45 142560.0 1570.0 0.04 -0.2893 -0.6377 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M09 mock treatment 128760.0 -12100.0 -0.32 135640.0 -5350.0 -0.14 -0.331 -0.9344 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M10 mock treatment 137400.0 -3450.0 -0.09 132520.0 -8470.0 -0.23 -0.2273 -0.9198 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M11 compound treatment 125040.0 -15800.0 -0.42 115360.0 -25600.0 -0.69 -0.7896 -0.9718 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M12 compound treatment 136800.0 -4050.0 -0.11 145760.0 4770.0 0.13 0.0148 0.0879 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M13 mock treatment 121920.0 -18900.0 -0.51 121800.0 -19200.0 -0.52 -0.7253 -0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M14 mock treatment 127640.0 -13200.0 -0.35 119840.0 -21200.0 -0.57 -0.6546 -0.9731 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M15 compound treatment 133320.0 -7530.0 -0.2 135520.0 -5470.0 -0.15 -0.247 -0.9886 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M16 compound treatment 119560.0 -21300.0 -0.57 121240.0 -19800.0 -0.53 -0.7807 -0.9995 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M17 compound treatment 128040.0 -12800.0 -0.34 151560.0 10600.0 0.29 -0.0399 -0.0893 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M18 compound treatment 121320.0 -19500.0 -0.52 124880.0 -16100.0 -0.44 -0.6777 -0.996 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M19 mock treatment 128000.0 -12800.0 -0.34 137920.0 -3070.0 -0.08 -0.3017 -0.8535 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M20 compound treatment 138840.0 -2010.0 -0.05 139960.0 -1030.0 -0.03 -0.0576 -0.9536 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M21 mock treatment 136960.0 -3890.0 -0.1 143880.0 2890.0 0.08 -0.0182 -0.1396 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M22 compound treatment 130040.0 -10800.0 -0.29 143240.0 2250.0 0.06 -0.1613 -0.5461 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M23 mock treatment 145680.0 4840.0 0.13 138600.0 -2390.0 -0.06 0.0457 0.316 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 M24 compound treatment 179040.0 38200.0 1.02 149480.0 8490.0 0.23 0.885 0.8451 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N01 compound treatment 196360.0 55500.0 1.48 191680.0 50700.0 1.37 2.0204 0.9992 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N02 compound treatment 72600.0 -68200.0 -1.83 28800.0 -112000.0 -3.04 -3.4385 -0.9703 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N03 compound treatment 135240.0 -5610.0 -0.15 132080.0 -8910.0 -0.24 -0.2766 -0.9738 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N04 compound treatment 138360.0 -2490.0 -0.07 131040.0 -9950.0 -0.27 -0.2375 -0.8559 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N05 compound treatment 154000.0 13200.0 0.35 154400.0 13400.0 0.36 0.5055 0.9999 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N06 compound treatment 149320.0 8480.0 0.23 131640.0 -9350.0 -0.25 -0.0187 -0.055 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N07 compound treatment 137720.0 -3130.0 -0.08 126280.0 -14700.0 -0.4 -0.3407 -0.8373 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N08 compound treatment 127760.0 -13100.0 -0.35 86720.0 -54300.0 -1.47 -1.2864 -0.8517 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N09 mock treatment 138400.0 -2450.0 -0.07 120960.0 -20000.0 -0.54 -0.4297 -0.7867 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N10 mock treatment 154240.0 13400.0 0.36 137160.0 -3830.0 -0.1 0.18 0.4827 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N11 compound treatment 142040.0 1200.0 0.03 120480.0 -20500.0 -0.56 -0.37 -0.6653 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N12 compound treatment 117520.0 -23300.0 -0.62 111560.0 -29400.0 -0.8 -1.0046 -0.9927 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N13 mock treatment 154480.0 13600.0 0.36 126320.0 -14700.0 -0.4 -0.0229 -0.0425 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N14 mock treatment 142000.0 1160.0 0.03 147280.0 6290.0 0.17 0.1423 0.822 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N15 compound treatment 124280.0 -16600.0 -0.44 122960.0 -18000.0 -0.49 -0.6585 -0.9988 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N16 compound treatment 131000.0 -9850.0 -0.26 124360.0 -16600.0 -0.45 -0.5046 -0.9674 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N17 compound treatment 120800.0 -20000.0 -0.54 122680.0 -18300.0 -0.5 -0.7296 -0.9992 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N18 compound treatment 96160.0 -44700.0 -1.2 14120.0 -127000.0 -3.43 -3.2739 -0.9002 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N19 compound treatment 117120.0 -23700.0 -0.63 122640.0 -18400.0 -0.5 -0.8 -0.9927 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N20 compound treatment 116080.0 -24800.0 -0.66 116600.0 -24400.0 -0.66 -0.9353 -1.0 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N21 compound treatment 134640.0 -6210.0 -0.17 149520.0 8530.0 0.23 0.0459 0.1615 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N22 compound treatment 118960.0 -21900.0 -0.59 73440.0 -67600.0 -1.83 -1.7071 -0.889 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N23 compound treatment 159960.0 19100.0 0.51 157560.0 16600.0 0.45 0.6787 0.9979 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 N24 compound treatment 9080.0 -132000.0 -3.52 8160.0 -133000.0 -3.6 -5.035 -0.9999 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O01 mock treatment 190200.0 49400.0 1.32 193320.0 52300.0 1.42 1.9353 0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O02 compound treatment 163560.0 22700.0 0.61 153440.0 12500.0 0.34 0.668 0.9614 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O03 mock treatment 150320.0 9480.0 0.25 130520.0 -10500.0 -0.28 -0.0212 -0.0558 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O04 mock treatment 134960.0 -5890.0 -0.16 140400.0 -590.0 -0.02 -0.1226 -0.7749 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O05 mock treatment 150960.0 10100.0 0.27 122360.0 -18600.0 -0.5 -0.1653 -0.2888 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O06 mock treatment 138040.0 -2810.0 -0.08 104080.0 -36900.0 -1.0 -0.7596 -0.7581 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O07 mock treatment 139200.0 -1650.0 -0.04 113600.0 -27400.0 -0.74 -0.5554 -0.7478 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O08 mock treatment 123920.0 -16900.0 -0.45 114160.0 -26800.0 -0.73 -0.8337 -0.9741 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O09 mock treatment 135440.0 -5410.0 -0.14 121840.0 -19200.0 -0.52 -0.4688 -0.8711 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O10 mock treatment 125160.0 -15700.0 -0.42 126760.0 -14200.0 -0.39 -0.5691 -0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O11 mock treatment 145360.0 4520.0 0.12 126960.0 -14000.0 -0.38 -0.1832 -0.4596 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O12 mock treatment 129240.0 -11600.0 -0.31 111040.0 -30000.0 -0.81 -0.7928 -0.9132 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O13 mock treatment 149880.0 9040.0 0.24 113680.0 -27300.0 -0.74 -0.3519 -0.4524 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O14 mock treatment 124600.0 -16200.0 -0.43 114360.0 -26600.0 -0.72 -0.817 -0.9706 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O15 mock treatment 139200.0 -1650.0 -0.04 129520.0 -11500.0 -0.31 -0.2507 -0.7993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O16 mock treatment 116000.0 -24800.0 -0.66 118920.0 -22100.0 -0.6 -0.8924 -0.9986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O17 mock treatment 122240.0 -18600.0 -0.5 120240.0 -20800.0 -0.56 -0.7491 -0.9982 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O18 mock treatment 122360.0 -18500.0 -0.49 115280.0 -25700.0 -0.7 -0.8418 -0.986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O19 mock treatment 134520.0 -6330.0 -0.17 130000.0 -11000.0 -0.3 -0.33 -0.9642 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O20 mock treatment 118840.0 -22000.0 -0.59 139600.0 -1390.0 -0.04 -0.4428 -0.7508 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O21 mock treatment 132840.0 -8010.0 -0.21 126680.0 -14300.0 -0.39 -0.4253 -0.9609 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O22 mock treatment 130240.0 -10600.0 -0.28 123640.0 -17400.0 -0.47 -0.5327 -0.9708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O23 mock treatment 140720.0 -125.0 0.0 136120.0 -4870.0 -0.13 -0.0956 -0.7248 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 O24 mock treatment 193800.0 53000.0 1.42 165760.0 24800.0 0.67 1.4758 0.9417 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P01 compound treatment 184160.0 43300.0 1.16 169120.0 28100.0 0.76 1.3578 0.9793 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P02 compound treatment 185720.0 44900.0 1.2 171520.0 30500.0 0.83 1.4332 0.9834 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P03 compound treatment 137800.0 -3050.0 -0.08 133760.0 -7230.0 -0.2 -0.196 -0.9245 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P04 compound treatment 118920.0 -21900.0 -0.59 99120.0 -41900.0 -1.13 -1.2162 -0.953 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P05 compound treatment 131200.0 -9650.0 -0.26 145040.0 4050.0 0.11 -0.1049 -0.3742 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P06 compound treatment 138200.0 -2650.0 -0.07 125800.0 -15200.0 -0.41 -0.3408 -0.8168 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P07 compound treatment 106760.0 -34100.0 -0.91 118520.0 -22500.0 -0.61 -1.0748 -0.9807 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P08 compound treatment 121440.0 -19400.0 -0.52 63840.0 -77200.0 -2.09 -1.8439 -0.8568 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P09 compound treatment 106680.0 -34200.0 -0.91 103120.0 -37900.0 -1.03 -1.3712 -0.9984 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P10 compound treatment 129760.0 -11100.0 -0.3 108120.0 -32900.0 -0.89 -0.8389 -0.8944 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P11 mock treatment 120360.0 -20500.0 -0.55 108080.0 -32900.0 -0.89 -1.0175 -0.9727 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P12 mock treatment 134120.0 -6730.0 -0.18 117120.0 -23900.0 -0.65 -0.5841 -0.8708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P13 compound treatment 120080.0 -20800.0 -0.56 108400.0 -32600.0 -0.88 -1.0166 -0.9751 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P14 compound treatment 113000.0 -27800.0 -0.74 100920.0 -40100.0 -1.08 -1.2937 -0.9832 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P15 compound treatment 105440.0 -35400.0 -0.95 99440.0 -41600.0 -1.12 -1.4651 -0.9963 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P16 compound treatment 128680.0 -12200.0 -0.33 110000.0 -31000.0 -0.84 -0.8233 -0.915 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P17 compound treatment 100920.0 -39900.0 -1.07 104360.0 -36600.0 -0.99 -1.4564 -0.9993 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P18 compound treatment 115600.0 -25200.0 -0.68 55480.0 -85500.0 -2.31 -2.1144 -0.8768 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P19 compound treatment 114200.0 -26600.0 -0.71 117120.0 -23900.0 -0.65 -0.9609 -0.9988 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P20 compound treatment 118880.0 -22000.0 -0.59 81080.0 -59900.0 -1.62 -1.5623 -0.9057 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P21 compound treatment 110040.0 -30800.0 -0.82 121840.0 -19200.0 -0.52 -0.9492 -0.9751 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P22 compound treatment 47840.0 -93000.0 -2.49 18240.0 -123000.0 -3.32 -4.1089 -0.9898 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P23 compound treatment 159320.0 18500.0 0.49 171680.0 30700.0 0.83 0.9369 0.9692 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2130 P24 compound treatment 87360.0 -53500.0 -1.43 66240.0 -74800.0 -2.02 -2.4426 -0.9856 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A01 compound treatment 220280.0 35700.0 0.95 197760.0 5110.0 0.14 0.7723 0.8012 1001670 ACon1_000001 COc1cc(O)c2C(=O)CC(Oc2c1)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A02 compound treatment 215320.0 30700.0 0.82 226000.0 33300.0 0.9 1.2191 0.9989 1023904 ACon1_000002 Oc1ccc2C(=O)c3cc(O)ccc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A03 compound treatment 11560.0 -173000.0 -4.63 11440.0 -181000.0 -4.91 -6.7423 -0.9996 3552049 ACon1_000003 C/C=C(\COC(=O)C)/C(=O)O[C@H]1[C@@H]2[C@H](OC(=O)C2=C)C3C(=C(C)[C@H]1O)C(=O)[C@H]4O[C@]43C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A04 compound treatment 204000.0 19400.0 0.52 209760.0 17100.0 0.46 0.6941 0.9984 1039 ACon1_000004 CC[C@]1(CCCN2CCc3c4[C@@H]21)CC(=O)n4c5ccccc35 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A05 compound treatment 191080.0 6460.0 0.17 236600.0 43900.0 1.19 0.9635 0.8014 3559511 ACon1_000005 COC(=O)CC(=O)OC[C@@]1(C)CCC[C@]2(C)[C@H]3CC[C@]4(C)C[C@@]3(CCC12)C=C4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A06 compound treatment 107560.0 -77100.0 -2.06 78480.0 -114000.0 -3.09 -3.6431 -0.9806 3551992 ACon1_000006 C/C/1=C\CCC2=CC(C\C(=C\C3OC(=O)C(=C)C3CC1)\C)OC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A07 compound treatment 115000.0 -69600.0 -1.86 72480.0 -120000.0 -3.25 -3.6173 -0.965 3189572 ACon1_000007 CN1Cc2c3OCOc3ccc2[C@H]4[C@@H](O)Cc5cc6OCOc6cc5[C@H]41 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A08 compound treatment 189240.0 4620.0 0.12 198080.0 5430.0 0.15 0.1913 0.9963 1116885 ACon1_000008 CCC(C)C1NC(=O)C(=C1O)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A09 compound treatment 180160.0 -4460.0 -0.12 188440.0 -4210.0 -0.11 -0.165 -0.9998 3559537 ACon1_000009 C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2C[C@]3(C)[C@@H](O)[C@@H](O)CC13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A10 compound treatment 165600.0 -19000.0 -0.51 181320.0 -11300.0 -0.31 -0.5767 -0.9707 3559847 ACon1_000010 OC[C@H]1O[C@@H](OCCC(=O)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A11 compound treatment 155080.0 -29500.0 -0.79 194200.0 1550.0 0.04 -0.5291 -0.6687 3559600 ACon1_000011 COc1ccc2oc(c(O)c(=O)c2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A12 compound treatment 105880.0 -78700.0 -2.11 130640.0 -62000.0 -1.68 -2.6764 -0.9937 3557478 ACon1_000012 CC(=CCc1c(O)ccc2C(=O)CC(Oc12)c3ccc(O)c(O)c3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A13 mock treatment 160120.0 -24500.0 -0.66 194080.0 1430.0 0.04 -0.4361 -0.6643 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A14 mock treatment 162680.0 -21900.0 -0.59 207560.0 14900.0 0.4 -0.1296 -0.182 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A15 compound treatment 167200.0 -17400.0 -0.47 186800.0 -5850.0 -0.16 -0.4415 -0.8971 1138815 ACon1_000013 COc1cccc2OC(CC(=O)c12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A16 compound treatment 132920.0 -51700.0 -1.38 143480.0 -49200.0 -1.33 -1.9192 -0.9998 3553257 ACon1_000014 CC(=O)N(O)CCCC1NC(=O)CNC(=O)CNC(=O)CNC(=O)C(CCCN(O)C(=O)C)NC(=O)C(CCCN(O)C(=O)C)NC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A17 compound treatment 175360.0 -9260.0 -0.25 199040.0 6390.0 0.17 -0.0529 -0.175 1527185 ACon1_000015 COc1ccccc1c2cc(=O)c3ccccc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A18 compound treatment 182200.0 -2420.0 -0.06 201200.0 8550.0 0.23 0.1179 0.4906 3558773 ACon1_000016 CC1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A19 compound treatment 191040.0 6420.0 0.17 224840.0 32200.0 0.87 0.7376 0.8305 3559667 ACon1_000017 CCC1=CC2CN3CCc4c([nH]c5ccccc45)[C@@](C2)([C@H]31)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A20 compound treatment 180040.0 -4580.0 -0.12 200120.0 7470.0 0.2 0.0563 0.2384 3558449 ACon1_000018 C[C@@H]1OC(OC[C@H]2O[C@@H](Oc3cc(O)c4c(=O)cc(oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A21 compound treatment 190120.0 5500.0 0.15 202720.0 10100.0 0.27 0.2968 0.9582 1530 ACon1_000019 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A22 compound treatment 200280.0 15700.0 0.42 207640.0 15000.0 0.41 0.5831 0.9999 3559224 ACon1_000020 CC(=O)c1ccc2OC(Cc2c1)C(=C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A23 compound treatment 248600.0 64000.0 1.71 263120.0 70500.0 1.91 2.5591 0.9985 3554786 ACon1_000021 COc1cc(/C=C/2\Oc3cc(O)ccc3C2=O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 A24 compound treatment 230440.0 45800.0 1.23 220600.0 27900.0 0.76 1.4017 0.9731 3559348 ACon1_000022 CC(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccccc2COC(=O)C3(O)C=CCCC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B01 compound treatment 6920.0 -178000.0 -4.75 7880.0 -185000.0 -5.0 -6.8982 -0.9997 3557968 ACon1_000023 CC(=CCc1c(O)c(CC=C(C)C)c2occ(c3ccc(O)cc3)c(=O)c2c1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B02 compound treatment 11200.0 -173000.0 -4.64 11880.0 -181000.0 -4.89 -6.7407 -0.9996 3555955 ACon1_000024 OCC(=C)C(=O)O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3[C@H](CC2=C)OC(=O)C(=C)CO)C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B03 compound treatment 221600.0 37000.0 0.99 199800.0 7150.0 0.19 0.8363 0.8297 3552206 ACon1_000025 C[C@@]1(CO)C(O)CC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B04 compound treatment 169000.0 -15600.0 -0.42 180920.0 -11700.0 -0.32 -0.52 -0.9909 3554785 ACon1_000026 COc1c2occ(COC(=O)C)c2c(C=O)c3c(C)cccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B05 compound treatment 211800.0 27200.0 0.73 202640.0 9990.0 0.27 0.7053 0.9092 3557493 ACon1_000027 CC1(C)CCCC2(C3CCC4CC3(CC4(O)CO)CCC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B06 compound treatment 165920.0 -18700.0 -0.5 188640.0 -4010.0 -0.11 -0.4305 -0.8411 3614336 ACon1_000028 CC[C@@H]1OC(=O)[C@@H](C)[C@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@@H](C)[C@H](O)[C@](C)(C[C@H](C)C(=O)[C@@H](C)[C@H](O)[C@@]1(C)O)O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B07 compound treatment 159680.0 -24900.0 -0.67 176600.0 -16100.0 -0.43 -0.779 -0.9785 3557846 ACon1_000029 O[C@@H]1[C@@H](O)[C@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)O[C@@H]([C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B08 compound treatment 156280.0 -28300.0 -0.76 177640.0 -15000.0 -0.41 -0.8234 -0.9573 3557557 ACon1_000030 C/C(=C/CC\C(=C\CC\C(=C\CC/C(=C\CO)/CO)\C)\C)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B09 compound treatment 166280.0 -18300.0 -0.49 183440.0 -9210.0 -0.25 -0.5232 -0.9508 3554854 ACon1_000031 COc1cc(C)cc(C(=O)O)c1C2=C(O)C(=O)c3c(O)cccc3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B10 compound treatment 159920.0 -24700.0 -0.66 162800.0 -29900.0 -0.81 -1.0386 -0.995 3553850 ACon1_000032 CC1(C)C[C@H](O)C[C@@]2(C)[C@H]1[C@H](O)C=C3COC(=O)[C@@]32O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B11 compound treatment 87480.0 -97100.0 -2.6 84840.0 -108000.0 -2.92 -3.9012 -0.9983 2060482 ACon1_000033 CC(C)c1cc2CCC3C(C)(C)CCC[C@]3(C(=O)O)c2c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B12 compound treatment 182080.0 -2540.0 -0.07 215040.0 22400.0 0.61 0.3805 0.624 3559288 ACon1_000034 CC1OC(OC2C(O)C(O[C@H]3[C@H](C)O[C@@H](OC4C(O)C(O)COC4OC(=O)[C@@]56CCC(C)(C)CC6C7=CCC8[C@@]9(C)C[C@H](O)[C@H](OC%10OC(CO)C(O)C(O)C%10O)[C@@](C)(CO)C9[C@H](O)C[C@@]8(C)[C@]7(C)CC5)[C@H](O)[C@@H]3O)OCC2O[C@H]%11OC[C@](O)(CO)[C@H]%11O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B13 mock treatment 165320.0 -19300.0 -0.52 198320.0 5670.0 0.15 -0.2565 -0.4764 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B14 mock treatment 166800.0 -17800.0 -0.48 180880.0 -11800.0 -0.32 -0.5624 -0.9809 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B15 compound treatment 12640.0 -172000.0 -4.6 16760.0 -176000.0 -4.76 -6.62 -0.9999 3559345 ACon1_000035 CC(=CCc1cc(cc(O)c1O)c2coc3c(CC=C(C)C)c(O)cc(O)c3c2=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B16 compound treatment 158640.0 -26000.0 -0.69 197960.0 5310.0 0.14 -0.3898 -0.5493 3554649 ACon1_000036 COC(=O)C(=C)[C@]1(O[C@]2(C)CC1=O)[C@H](C[C@@]3(C)OC(=O)/C(=C/C)/[C@]3(O)CC2)OC(=O)C(CO)CN4CCCC4C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B17 compound treatment 165000.0 -19600.0 -0.52 189080.0 -3570.0 -0.1 -0.4395 -0.8236 3559460 ACon1_000037 CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B18 compound treatment 170160.0 -14500.0 -0.39 188680.0 -3970.0 -0.11 -0.3495 -0.8707 3557695 ACon1_000038 COC(=O)[C@@]1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6OC[C@@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B19 compound treatment 157160.0 -27500.0 -0.73 196360.0 3710.0 0.1 -0.4484 -0.6049 3558409 ACon1_000039 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B20 compound treatment 188520.0 3900.0 0.1 193960.0 1310.0 0.04 0.0988 0.8967 3557530 ACon1_000040 COC(=O)C(=C)[C@@H]1[C@@H](O)C[C@@]2(COC(=O)C(=C)[C@@H]2[C@H]1O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B21 compound treatment 174880.0 -9740.0 -0.26 203720.0 11100.0 0.3 0.0277 0.0697 3559391 ACon1_000041 COc1cc(cc(OC)c1O)C2C(CO[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)O)C(CO)Cc4cc(OC)c(O)c(O)c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B22 compound treatment 14880.0 -170000.0 -4.54 17000.0 -176000.0 -4.76 -6.573 -0.9997 3557713 ACon1_000042 CO[C@H]1[C@@H](O)[C@@H](C)O[C@@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4(O)CC(OC(=O)C)C3=C2)C6=CC(=O)OC6)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B23 compound treatment 190040.0 5420.0 0.15 204760.0 12100.0 0.33 0.3343 0.9327 3559546 ACon1_000043 CC12CCC=C(CO)C2CC3C(C1)OC(=O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 B24 compound treatment 197640.0 13000.0 0.35 213680.0 21000.0 0.57 0.6488 0.9722 3557636 ACon1_000044 OC(=O)[C@@H](OC(=O)/C=C/c1ccc(O)c(O)c1)[C@](O)(Cc2ccc(O)c(O)c2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C01 compound treatment 122360.0 -62300.0 -1.67 146440.0 -46200.0 -1.25 -2.0622 -0.9901 3558824 ACon1_000045 OCC(=C)C(=O)O[C@H]1CC(=C)[C@@H]2C[C@H](O)C(=C)[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C02 compound treatment 173680.0 -10900.0 -0.29 235040.0 42400.0 1.15 0.6045 0.5105 3559748 ACon1_000046 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C03 compound treatment 178080.0 -6540.0 -0.17 186280.0 -6370.0 -0.17 -0.2457 -1.0 831758 ACon1_000047 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C04 compound treatment 199560.0 14900.0 0.4 221840.0 29200.0 0.79 0.8413 0.9501 1054577 ACon1_000048 COc1cc(cc(OC)c1OC)c2cc(=O)c3c(O)c(OC)c(OC)c(OC)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C05 compound treatment 163360.0 -21300.0 -0.57 185600.0 -7050.0 -0.19 -0.5371 -0.8954 3558524 ACon1_000049 COc1c(O)c2c(=O)c(O)c(oc2c(OC)c1OC)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C06 compound treatment 156480.0 -28100.0 -0.75 172920.0 -19700.0 -0.53 -0.91 -0.9859 3559371 ACon1_000050 COC(=O)C1=CO[C@@H](OC2OC(O)C(O)C(O)C2CO)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C07 compound treatment 11400.0 -173000.0 -4.63 15680.0 -177000.0 -4.79 -6.6641 -0.9999 3559455 ACon1_000051 COc1cc(/C=C/C(=O)OC2CC3CCC2(C)C3(C)C)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C08 compound treatment 153120.0 -31500.0 -0.84 169520.0 -23100.0 -0.63 -1.0386 -0.9893 3559354 ACon1_000052 CC(CCC1(C)C(C)CCC2(C)C1CC(=O)C=C2C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C09 compound treatment 141080.0 -43500.0 -1.16 181960.0 -10700.0 -0.29 -1.0282 -0.8568 3553479 ACon1_000053 CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C10 compound treatment 154960.0 -29700.0 -0.79 206080.0 13400.0 0.36 -0.3039 -0.3483 3553171 ACon1_000054 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)[C@H]([C@H](O)C(C)(C)C5CC[C@]43C)C(=O)O)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C11 mock treatment 146920.0 -37700.0 -1.01 174000.0 -18700.0 -0.5 -1.0701 -0.9489 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C12 mock treatment 156400.0 -28200.0 -0.75 183880.0 -8770.0 -0.24 -0.7017 -0.8867 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C13 compound treatment 153680.0 -30900.0 -0.83 179600.0 -13100.0 -0.35 -0.8351 -0.928 1016235 ACon1_000055 O=c1cc(oc2ccccc12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C14 compound treatment 154760.0 -29900.0 -0.8 174000.0 -18700.0 -0.5 -0.9218 -0.9756 3553953 ACon1_000056 CC12CC3(CC2C1CC34)CC(O)C5C(CO)(CO)CC(=O)CC45C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C15 mock treatment 182240.0 -2380.0 -0.06 189560.0 -3090.0 -0.08 -0.1042 -0.9908 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C16 mock treatment 147720.0 -36900.0 -0.99 191120.0 -1530.0 -0.04 -0.7273 -0.7362 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C17 compound treatment 153360.0 -31300.0 -0.84 185080.0 -7570.0 -0.21 -0.7362 -0.8552 1134 ACon1_000057 CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C18 compound treatment 154600.0 -30000.0 -0.8 188600.0 -4050.0 -0.11 -0.6454 -0.7963 3557809 ACon1_000058 COc1cc(/C=C/CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C19 compound treatment 12400.0 -172000.0 -4.61 16360.0 -176000.0 -4.77 -6.6322 -0.9998 3559685 ACon1_000059 COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)CCc2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C20 compound treatment 165680.0 -18900.0 -0.51 178040.0 -14600.0 -0.4 -0.638 -0.9925 3559829 ACon1_000060 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C21 compound treatment 176680.0 -7940.0 -0.21 183360.0 -9290.0 -0.25 -0.3281 -0.9964 297849 ACon1_000061 COc1ccc2c(c1)[nH]c3c(C)nccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C22 compound treatment 164520.0 -20100.0 -0.54 179920.0 -12700.0 -0.34 -0.6239 -0.9769 3559835 ACon1_000062 COc1cc2ccc(=O)oc2c(CC=C(C)C)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C23 compound treatment 27600.0 -157000.0 -4.2 28760.0 -164000.0 -4.44 -6.1073 -0.9996 3559675 ACon1_000063 Oc1ccc(cc1)[C@@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2[C@H]4[C@@H](Oc5cc(O)cc(O)c5C4=O)c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 C24 compound treatment 184560.0 -58.7 0.0 189640.0 -3010.0 -0.08 -0.0588 -0.7206 3557563 ACon1_000064 CC(=CC(O)C/C(=C/COc1ccc2ccc(=O)oc2c1)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D01 compound treatment 128440.0 -56200.0 -1.5 200120.0 7470.0 0.2 -0.9196 -0.6065 4614 ACon1_000065 CCCCCCC/C=C\[C@H](O)C#CC#C[C@@H](O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D02 compound treatment 46120.0 -138000.0 -3.7 64600.0 -128000.0 -3.47 -5.0709 -0.9994 3559481 ACon1_000066 C/C/1=C\[C@H]2OC(=O)C(=C)C2[C@@H](C\C(=C\CC1)\C)OC(=O)\C(=C\CO)\CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D03 compound treatment 190040.0 5420.0 0.15 214120.0 21500.0 0.58 0.5135 0.8573 3558310 ACon1_000067 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D04 compound treatment 14400.0 -170000.0 -4.55 15600.0 -177000.0 -4.79 -6.6089 -0.9997 3559638 ACon1_000068 CC(=CCc1c(O)cc2OC(CC(=O)c2c1O)c3ccc(O)cc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D05 compound treatment 192000.0 7380.0 0.2 186200.0 -6450.0 -0.17 0.0161 0.061 3555862 ACon1_000069 OC(=O)CCCCCCC/C=C/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D06 compound treatment 172880.0 -11700.0 -0.31 235760.0 43100.0 1.17 0.6032 0.4991 3559157 ACon1_000070 COc1c(CO)c(O)cc2C(=O)c3ccccc3C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D07 compound treatment 137280.0 -47300.0 -1.27 167280.0 -25400.0 -0.69 -1.3811 -0.9587 3557565 ACon1_000071 CC(=CCC/C(=C/COc1ccc2ccc(=O)oc2c1)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D08 compound treatment 153480.0 -31100.0 -0.83 218520.0 25900.0 0.7 -0.0938 -0.0862 3554888 ACon1_000072 COc1cc(ccc1O)c2oc3cc(O)c(OC)c(O)c3c(=O)c2O[C@@H]4O[C@H](CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O[C@@H]6OCC(O)(CO)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D09 compound treatment 153000.0 -31600.0 -0.85 187440.0 -5210.0 -0.14 -0.6978 -0.8138 3558155 ACon1_000073 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)c(oc3c2)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D10 compound treatment 160320.0 -24300.0 -0.65 185480.0 -7170.0 -0.19 -0.5969 -0.8799 3614338 ACon1_000074 CC(C)C(NC(=O)c1ccc(O)cc1)C(=O)N2CCCC2C(=O)Nc3c(O)cccc3C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D11 mock treatment 149320.0 -35300.0 -0.94 229080.0 36400.0 0.99 0.0297 0.0217 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D12 mock treatment 154160.0 -30500.0 -0.81 195440.0 2790.0 0.08 -0.5228 -0.6389 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D13 compound treatment 150880.0 -33700.0 -0.9 198280.0 5630.0 0.15 -0.5304 -0.5796 1251 ACon1_000075 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D14 compound treatment 140240.0 -44400.0 -1.19 197040.0 4390.0 0.12 -0.7554 -0.6332 3554269 ACon1_000076 CCCCCC(O)CC(O)CC(=O)OC(CC(O)CCCCC)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D15 mock treatment 159720.0 -24900.0 -0.67 207120.0 14500.0 0.39 -0.194 -0.2511 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D16 mock treatment 152000.0 -32600.0 -0.87 210280.0 17600.0 0.48 -0.2795 -0.2811 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D17 compound treatment 151560.0 -33100.0 -0.88 186920.0 -5730.0 -0.16 -0.735 -0.8187 3559890 ACon1_000077 COc1c(O)cc2occ(c3ccccc3O)c(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D18 compound treatment 153960.0 -30700.0 -0.82 172640.0 -20000.0 -0.54 -0.963 -0.9798 3557697 ACon1_000078 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D19 compound treatment 153680.0 -30900.0 -0.83 220720.0 28100.0 0.76 -0.0479 -0.0426 3557614 ACon1_000079 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D20 compound treatment 66040.0 -119000.0 -3.17 83680.0 -109000.0 -2.95 -4.3289 -0.9993 3554651 ACon1_000080 COC(=O)C(=C)[C@H]1[C@H](O)C2C(=C)C(=O)OC[C@]2(C[C@@H]1OC(=O)C(=C)CO)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D21 compound treatment 176240.0 -8380.0 -0.22 210840.0 18200.0 0.49 0.1897 0.3506 3558580 ACon1_000081 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D22 compound treatment 182760.0 -1860.0 -0.05 198000.0 5350.0 0.14 0.0672 0.4391 3557892 ACon1_000082 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C)[C@H]3C[C@H](OC(=O)C)[C@](O)(COC(=O)C)[C@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D23 compound treatment 185960.0 1340.0 0.04 247120.0 54500.0 1.47 1.068 0.7241 3559584 ACon1_000083 CC1(C)[C@H](O)CC[C@@]2(C)[C@@H]3CC[C@@](C)(CC3=CC[C@H]12)C(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 D24 compound treatment 31680.0 -153000.0 -4.09 34480.0 -158000.0 -4.28 -5.9207 -0.9997 3554996 ACon1_000084 COC1CC(O[C@H]2CC[C@@]3(C)[C@H](CC[C@]4(CC[C@H](C5=CC(=O)OC5)[C@@]6(C)CCC34)C6=O)C2)OC(C)C1OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E01 mock treatment 175720.0 -8900.0 -0.24 172200.0 -20500.0 -0.55 -0.5598 -0.9289 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E02 mock treatment 163960.0 -20700.0 -0.55 199000.0 6350.0 0.17 -0.2692 -0.4653 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E03 compound treatment 179880.0 -4740.0 -0.13 177320.0 -15300.0 -0.42 -0.3832 -0.8828 451 ACon1_000085 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E04 compound treatment 158560.0 -26100.0 -0.7 176240.0 -16400.0 -0.44 -0.8071 -0.9764 687 ACon1_000086 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E05 compound treatment 173120.0 -11500.0 -0.31 169480.0 -23200.0 -0.63 -0.6611 -0.9462 1225 ACon1_000087 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E06 compound treatment 116160.0 -68500.0 -1.83 154640.0 -38000.0 -1.03 -2.0225 -0.9629 3557593 ACon1_000088 C/C(=C/CO)/CC[C@@H]1[C@@](C)(O)CCC2C(C)(C)CCC[C@@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E07 compound treatment 34160.0 -150000.0 -4.02 33760.0 -159000.0 -4.3 -5.8875 -0.9994 3559517 ACon1_000089 C[C@@H]1CC[C@]2(C)[C@H](CCC=C2C)[C@]1(CCc3ccoc3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E08 compound treatment 177440.0 -7180.0 -0.19 171560.0 -21100.0 -0.57 -0.5396 -0.8956 3557755 ACon1_000090 COc1cc(CCCO)cc2C(CO)C(Oc21)c3ccc(O[C@H]4O[C@H](C)[C@@H](O)[C@H](O)[C@@H]4O)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E09 mock treatment 142080.0 -42500.0 -1.14 179520.0 -13100.0 -0.36 -1.056 -0.8858 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E10 mock treatment 166160.0 -18500.0 -0.49 159080.0 -33600.0 -0.91 -0.9918 -0.9589 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E11 compound treatment 160720.0 -23900.0 -0.64 178640.0 -14000.0 -0.38 -0.7203 -0.969 3559616 ACon1_000091 CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E12 compound treatment 143200.0 -41400.0 -1.11 164920.0 -27700.0 -0.75 -1.3143 -0.982 3557829 ACon1_000092 CC(C)(O)[C@@H]1CC[C@@]2(C)C[C@@H](O)CC(=C)C2C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E13 compound treatment 158840.0 -25800.0 -0.69 167600.0 -25100.0 -0.68 -0.9672 -1.0 1052342 ACon1_000093 Oc1ccc2c(=O)cc(oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E14 compound treatment 168160.0 -16500.0 -0.44 157600.0 -35100.0 -0.95 -0.9823 -0.939 3555904 ACon1_000094 OC[C@H]1O[C@@H](Oc2cc(O)cc3OC(O)(Cc4ccc(O)cc4)C(=O)c32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E15 compound treatment 142920.0 -41700.0 -1.12 185080.0 -7570.0 -0.21 -0.9337 -0.8233 3554527 ACon1_000095 COC(=O)[C@@]1(O)C=CC[C@@H]2[C@@]3(C)C[C@H](OC(=O)[C@H]3CC[C@]21C)c4ccoc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E16 compound treatment 154360.0 -30300.0 -0.81 190880.0 -1770.0 -0.05 -0.6063 -0.7477 3558041 ACon1_000096 O[C@H]1CO[C@@H](OC[C@H]2O[C@@H](OC/C=C/c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E17 mock treatment 142200.0 -42400.0 -1.13 174600.0 -18100.0 -0.49 -1.1479 -0.9292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E18 mock treatment 147400.0 -37200.0 -1.0 159000.0 -33700.0 -0.91 -1.3482 -0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E19 compound treatment 141080.0 -43500.0 -1.16 180120.0 -12500.0 -0.34 -1.0634 -0.8767 976 ACon1_000097 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E20 compound treatment 153720.0 -30900.0 -0.83 164160.0 -28500.0 -0.77 -1.1299 -0.9994 3554687 ACon1_000098 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E21 compound treatment 191600.0 6980.0 0.19 195000.0 2350.0 0.06 0.177 0.8972 3553328 ACon1_000099 CC(=O)O[C@@H]1[C@H]2CC[C@@H]3[C@@]1(C[C@@]2(C)O)C[C@@H](O)[C@@]4(O)[C@@H](C[C@H](O)C4(C)C)[C@]3(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E22 compound treatment 163240.0 -21400.0 -0.57 186760.0 -5890.0 -0.16 -0.5172 -0.8711 3559845 ACon1_000100 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E23 compound treatment 195720.0 11100.0 0.3 173240.0 -19400.0 -0.53 -0.1617 -0.2678 1013994 ACon1_000101 Oc1ccc(O)c2C(=O)c3ccccc3C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 E24 compound treatment 174160.0 -10500.0 -0.28 186840.0 -5810.0 -0.16 -0.3091 -0.963 3554732 ACon1_000102 COC(=O)c1cccc2nc3c(cccc3nc12)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F01 mock treatment 197680.0 13100.0 0.35 195520.0 2870.0 0.08 0.3019 0.8436 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F02 mock treatment 212080.0 27500.0 0.73 200760.0 8110.0 0.22 0.6746 0.8799 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F03 compound treatment 179800.0 -4820.0 -0.13 182880.0 -9770.0 -0.26 -0.2782 -0.9454 3557765 ACon1_000103 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4cc(O)c(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F04 compound treatment 159040.0 -25600.0 -0.68 185320.0 -7330.0 -0.2 -0.6242 -0.8761 3559590 ACon1_000104 CC1=CC(=O)C2=C(C)CCC3[C@H](OC(=O)C3=C)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F05 compound treatment 179640.0 -4980.0 -0.13 202960.0 10300.0 0.28 0.1031 0.3336 3557685 ACon1_000105 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F06 compound treatment 161920.0 -22700.0 -0.61 178280.0 -14400.0 -0.39 -0.7045 -0.9769 3554203 ACon1_000106 CCc1c(O)cc(OC)c2C(=O)C[C@@H](C)Oc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F07 compound treatment 83240.0 -101000.0 -2.71 127440.0 -65200.0 -1.77 -3.1659 -0.9784 3558903 ACon1_000107 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@](C)(CO)C5CC[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F08 compound treatment 152160.0 -32500.0 -0.87 186600.0 -6050.0 -0.16 -0.7298 -0.826 3557773 ACon1_000108 COc1cc(/C=C/CO)cc(OC)c1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F09 mock treatment 153440.0 -31200.0 -0.83 182200.0 -10500.0 -0.28 -0.7898 -0.8968 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F10 mock treatment 145960.0 -38700.0 -1.03 163520.0 -29100.0 -0.79 -1.2889 -0.9911 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F11 compound treatment 151400.0 -33200.0 -0.89 168520.0 -24100.0 -0.65 -1.0903 -0.9886 3559308 ACon1_000109 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](OC(=O)C)[C@@H](O)[C@H]4O)c(oc3c2)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F12 compound treatment 147520.0 -37100.0 -0.99 208000.0 15300.0 0.42 -0.4079 -0.3792 1216977 ACon1_000110 CC1(C)Oc2ccc3ccc(=O)oc3c2CC1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F13 compound treatment 142600.0 -42000.0 -1.12 180920.0 -11700.0 -0.32 -1.0194 -0.8728 3559144 ACon1_000111 CC1CCC2(CCC3(C)C(=CCC4C5(C)C[C@@H](O)[C@@H](O)C(C)(CO)C5CCC43C)C2C1(C)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F14 compound treatment 160000.0 -24600.0 -0.66 173400.0 -19300.0 -0.52 -0.8342 -0.9933 3552034 ACon1_000112 C/C=C(\C)/C(=O)OC(\C=C\C(O)C(C)O)C1OC(=O)C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F15 compound treatment 157040.0 -27600.0 -0.74 204600.0 11900.0 0.32 -0.2929 -0.3637 3552812 ACon1_000113 C[C@@H]1OC(O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)/C=C/c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F16 compound treatment 179560.0 -5060.0 -0.14 198600.0 5950.0 0.16 0.0182 0.0864 3557622 ACon1_000114 COc1ccc(CCC(=O)O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F17 mock treatment 145040.0 -39600.0 -1.06 184640.0 -8010.0 -0.22 -0.902 -0.8347 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F18 mock treatment 163000.0 -21600.0 -0.58 169200.0 -23500.0 -0.63 -0.8579 -0.9989 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F19 compound treatment 152200.0 -32400.0 -0.87 187120.0 -5530.0 -0.15 -0.7191 -0.8172 3552693 ACon1_000115 C[C@@H]1CC[C@@]2(CC[C@]3(C)C4=CCC5C(C)(C)[C@H](CC[C@]5(C)C4CC[C@@]3(C)[C@@H]2[C@H]1C)O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F20 compound treatment 160360.0 -24300.0 -0.65 184520.0 -8130.0 -0.22 -0.6145 -0.8968 3554774 ACon1_000116 COc1c(OC/C=C(\C)/CC2OC(=O)C(=C2)C)ccc3ccc(=O)oc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F21 compound treatment 150200.0 -34400.0 -0.92 193400.0 747.0 0.02 -0.6367 -0.6914 3559078 ACon1_000117 CC1OC(OC2C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC65C)C(=O)OC8OC(CO)C(O)C(O)C8O)C3(C)C)OC(C2O)C(=O)O)C(OC9OC(CO)C(O)C(O)C9O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F22 compound treatment 124720.0 -59900.0 -1.6 172560.0 -20100.0 -0.54 -1.5176 -0.8969 3557936 ACon1_000118 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)c(c4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)cc6)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F23 compound treatment 199040.0 14400.0 0.39 189640.0 -3010.0 -0.08 0.2151 0.5455 3553532 ACon1_000119 CC(C)C(=O)OC1c2c(C)coc2C(=O)C3[C@@H](O)CC[C@H](C)[C@@]13C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 F24 compound treatment 182640.0 -1980.0 -0.05 212000.0 19300.0 0.52 0.3329 0.6324 3614339 ACon1_000120 O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G01 compound treatment 136120.0 -48500.0 -1.3 124240.0 -68400.0 -1.85 -2.227 -0.9848 3559490 ACon1_000121 CC1(C)CCC[C@@]2(C)[C@H](CC/C(=C/CO)/CO)C(=CCC12)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G02 compound treatment 165360.0 -19300.0 -0.52 198480.0 5830.0 0.16 -0.2527 -0.4691 3060043 ACon1_000122 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G03 mock treatment 176720.0 -7900.0 -0.21 180200.0 -12500.0 -0.34 -0.3878 -0.9747 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G04 mock treatment 168040.0 -16600.0 -0.44 170840.0 -21800.0 -0.59 -0.7311 -0.99 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G05 compound treatment 166520.0 -18100.0 -0.48 173240.0 -19400.0 -0.53 -0.714 -0.9992 3559421 ACon1_000123 C[C@H](C[C@@H]1CC=CC(=O)O1)OC(=O)CCc2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G06 compound treatment 126120.0 -58500.0 -1.56 153560.0 -39100.0 -1.06 -1.8548 -0.9819 3559357 ACon1_000124 COc1cc(OC)c(C(=O)/C=C/c2ccccc2)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G07 compound treatment 156200.0 -28400.0 -0.76 143320.0 -49300.0 -1.34 -1.4819 -0.9643 3559500 ACon1_000125 C[C@@]1(CCC2C(=C1)CCC3[C@@](C)(CCCC23C)C(=O)O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G08 compound treatment 12200.0 -172000.0 -4.61 13720.0 -179000.0 -4.84 -6.6865 -0.9997 3553967 ACon1_000126 CC1CC(=O)c2c(O)c3c(O)cc(O)c(c4c(O)cc(O)c5c(O)c6C(=O)CC(C)Oc6cc45)c3cc2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G09 compound treatment 148800.0 -35800.0 -0.96 154360.0 -38300.0 -1.04 -1.4105 -0.9992 3559571 ACon1_000127 COC(=O)/C=C(/CC[C@@H]1C(=C)CC[C@@H]2C(C)(C)CCC[C@@]12C)\COC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G10 compound treatment 166000.0 -18600.0 -0.5 155360.0 -37300.0 -1.01 -1.0661 -0.947 3557671 ACon1_000128 OCCC(=O)c1ccc(O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G11 compound treatment 25600.0 -159000.0 -4.25 47480.0 -145000.0 -3.93 -5.7868 -0.9992 3559625 ACon1_000129 COC(=O)C1(C)CCCC(=C)C1CC/C(=C/CCc2ccoc2)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G12 compound treatment 156360.0 -28300.0 -0.76 184520.0 -8130.0 -0.22 -0.6902 -0.8766 3554892 ACon1_000130 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G13 compound treatment 150840.0 -33800.0 -0.9 195000.0 2350.0 0.06 -0.594 -0.6558 3552088 ACon1_000131 C/C=C/C=C/C(=O)NCCc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G14 compound treatment 150840.0 -33800.0 -0.9 149000.0 -43700.0 -1.18 -1.4746 -0.9912 3554659 ACon1_000132 COC(=O)C1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(=C1c3ccc(O)cc3)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G15 compound treatment 107400.0 -77200.0 -2.07 149160.0 -43500.0 -1.18 -2.2931 -0.9645 3559582 ACon1_000133 CC1=CC[C@H](O)[C@@]2(C)C[C@@H](O)[C@@H]3[C@@H](OC(=O)C3=C)[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G16 compound treatment 153240.0 -31400.0 -0.84 157960.0 -34700.0 -0.94 -1.2576 -0.9984 3552120 ACon1_000134 C[C@@]1(C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12)OC(=O)/C=C/c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G17 compound treatment 143960.0 -40700.0 -1.09 150040.0 -42600.0 -1.15 -1.5848 -0.9996 926 ACon1_000135 Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G18 compound treatment 147760.0 -36900.0 -0.99 154040.0 -38600.0 -1.05 -1.4363 -0.9996 3559321 ACon1_000136 CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)C3[C@H](O)CC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)C6CC[C@]54C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G19 mock treatment 151280.0 -33300.0 -0.89 186720.0 -5930.0 -0.16 -0.7442 -0.8213 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G20 mock treatment 176920.0 -7700.0 -0.21 164760.0 -27900.0 -0.76 -0.6796 -0.8682 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G21 compound treatment 176280.0 -8340.0 -0.22 209920.0 17300.0 0.47 0.1728 0.3337 3559673 ACon1_000137 CC(=O)OCC1=C[C@@H](O)[C@@H]2C=CO[C@@H](OC3OC(CO)C(O)C(O)C3O)[C@@H]21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G22 compound treatment 161040.0 -23600.0 -0.63 187800.0 -4850.0 -0.13 -0.5389 -0.8365 3557624 ACon1_000138 COc1ccc(/C=C/C(=O)O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G23 compound treatment 177000.0 -7620.0 -0.2 182760.0 -9890.0 -0.27 -0.3335 -0.9909 895 ACon1_000139 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 G24 compound treatment 191640.0 7020.0 0.19 195520.0 2870.0 0.08 0.1877 0.9236 3551965 ACon1_000140 C/C(=C\CC[C@](C)(O)C=C)/C(=O)O[C@@H]1[C@@H]2O[C@]2(C)[C@H]3[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C[C@@]13O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H01 compound treatment 228440.0 43800.0 1.17 197360.0 4710.0 0.13 0.919 0.7794 3559838 ACon1_000141 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H02 compound treatment 177160.0 -7460.0 -0.2 203240.0 10600.0 0.29 0.0616 0.1764 3559607 ACon1_000142 COC1=CC(=O)O[C@@H](CCc2ccccc2)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H03 mock treatment 172160.0 -12500.0 -0.33 180240.0 -12400.0 -0.34 -0.4733 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H04 mock treatment 172880.0 -11700.0 -0.31 205240.0 12600.0 0.34 0.0189 0.0408 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H05 compound treatment 178320.0 -6300.0 -0.17 174520.0 -18100.0 -0.49 -0.4663 -0.8984 1322 ACon1_000143 COc1cc2ccc(=O)oc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H06 compound treatment 149120.0 -35500.0 -0.95 176040.0 -16600.0 -0.45 -0.9895 -0.9417 3559370 ACon1_000144 COc1cc2oc(=O)ccc2cc1CC(O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H07 compound treatment 15440.0 -169000.0 -4.53 15480.0 -177000.0 -4.8 -6.5915 -0.9996 3558770 ACon1_000145 Oc1cc(cc(O)c1O)C(=O)OC[C@H]2O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](OC(=O)c4cc(O)c(O)c(O)c4)[C@@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@@H]2OC(=O)c6cc(O)c(O)c(O)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H08 compound treatment 151080.0 -33500.0 -0.9 162360.0 -30300.0 -0.82 -1.2143 -0.999 3557705 ACon1_000146 O=C(/C=C/CCc1ccc2OCOc2c1)N3CCCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H09 compound treatment 40320.0 -144000.0 -3.86 36560.0 -156000.0 -4.23 -5.7174 -0.999 3553890 ACon1_000147 CC1(O)CC(=O)c2c(C1)ccc3C(=O)c4c(O)cccc4C(=O)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H10 compound treatment 160760.0 -23900.0 -0.64 185160.0 -7490.0 -0.2 -0.5947 -0.8881 3554182 ACon1_000148 CCC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H11 compound treatment 149560.0 -35100.0 -0.94 183040.0 -9610.0 -0.26 -0.8471 -0.8704 3557869 ACon1_000149 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H12 compound treatment 161360.0 -23300.0 -0.62 171280.0 -21400.0 -0.58 -0.8491 -0.9993 3555354 ACon1_000150 COc1oc2cccc(C)c2c(=O)c1C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H13 compound treatment 153560.0 -31100.0 -0.83 159240.0 -33400.0 -0.9 -1.2271 -0.9991 3553324 ACon1_000151 CC(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](COC(=O)C2(O)C=CCCC2=O)O[C@H]1Oc3ccccc3COC(=O)C4(O)C=CCCC4=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H14 compound treatment 118480.0 -66100.0 -1.77 130680.0 -62000.0 -1.68 -2.4373 -0.9996 3557583 ACon1_000152 CC1CCC2=C(CCCC2(C)C(=O)O)C1(C)CCc3ccoc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H15 compound treatment 157120.0 -27500.0 -0.74 187920.0 -4730.0 -0.13 -0.6107 -0.818 3558739 ACon1_000153 COc1cc(OC)c2ccc(=O)oc2c1CC(O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H16 compound treatment 21080.0 -164000.0 -4.37 21680.0 -171000.0 -4.63 -6.3662 -0.9996 3557708 ACon1_000154 C[C@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)C4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H17 compound treatment 138680.0 -45900.0 -1.23 168120.0 -24500.0 -0.66 -1.3385 -0.9583 3557703 ACon1_000155 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H18 compound treatment 207960.0 23300.0 0.62 169920.0 -22700.0 -0.62 0.0063 0.0072 3557644 ACon1_000156 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@H](O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC[C@@]78OC[C@@]9(CCC(C)(C)CC98)[C@H](O)C[C@]76C)C4(C)C)[C@@H]3O[C@@H]%10O[C@H](CO)[C@@H](O[C@@H]%11OC[C@@H](O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H19 mock treatment 148120.0 -36500.0 -0.98 189000.0 -3650.0 -0.1 -0.7603 -0.7748 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H20 mock treatment 159840.0 -24800.0 -0.66 161880.0 -30800.0 -0.83 -1.0578 -0.9936 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H21 compound treatment 168360.0 -16300.0 -0.43 160560.0 -32100.0 -0.87 -0.9219 -0.9488 3559541 ACon1_000157 C[C@]12C[C@H]3OC(=O)C(=C)[C@H]3C[C@H]2C(=C)[C@H](O)C[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H22 compound treatment 205320.0 20700.0 0.55 169000.0 -23700.0 -0.64 -0.0612 -0.0723 3557933 ACon1_000158 C/C=C(/C)\C(=O)OC1C(OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H23 compound treatment 191160.0 6540.0 0.17 205520.0 12900.0 0.35 0.37 0.9493 3555130 ACon1_000159 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O)c(OC)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 H24 compound treatment 185920.0 1300.0 0.03 196760.0 4110.0 0.11 0.1032 0.8861 3557750 ACon1_000160 O[C@@H]1C=C(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I01 compound treatment 14560.0 -170000.0 -4.55 11520.0 -181000.0 -4.9 -6.684 -0.9993 3559527 ACon1_000161 CC1=CC[C@@H]2[C@H]1[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](CC2=C)OC(=O)/C(=C/CO)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I02 compound treatment 176280.0 -8340.0 -0.22 174760.0 -17900.0 -0.48 -0.5003 -0.938 2120761 ACon1_000162 COc1cc(OC)c(C(=O)/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I03 compound treatment 27960.0 -157000.0 -4.19 81760.0 -111000.0 -3.0 -5.0859 -0.9866 3559509 ACon1_000163 COC(=O)CCC(=O)OC[C@]1(C)CCC[C@@]2(C)C3CC[C@@]4(C)CC3(CCC12)C=C4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I04 compound treatment 207440.0 22800.0 0.61 184000.0 -8650.0 -0.23 0.266 0.4068 3557562 ACon1_000164 C/C(=C\COc1ccc2ccc(=O)oc2c1)/CC3OC(=O)C(=C3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I05 mock treatment 172360.0 -12300.0 -0.33 174840.0 -17800.0 -0.48 -0.5729 -0.9823 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I06 mock treatment 181240.0 -3380.0 -0.09 205240.0 12600.0 0.34 0.177 0.5022 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I07 compound treatment 102400.0 -82200.0 -2.2 96600.0 -96100.0 -2.6 -3.3939 -0.9965 3552640 ACon1_000165 C[C@@H]1C[C@@H]2OC(=O)C(=C)[C@H]2C[C@@]3(C)[C@H]1CCC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I08 compound treatment 120600.0 -64000.0 -1.71 90200.0 -102000.0 -2.77 -3.1721 -0.9731 3557649 ACon1_000166 COc1c(O)c2c(=O)cc(oc2cc1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I09 compound treatment 36920.0 -148000.0 -3.95 23520.0 -169000.0 -4.58 -6.0314 -0.9973 1036721 ACon1_000167 Oc1c(oc2ccccc2c1=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I10 compound treatment 162560.0 -22100.0 -0.59 183480.0 -9170.0 -0.25 -0.5928 -0.926 3555603 ACon1_000168 O[C@@H]1[C@@H](O)[C@H](Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)O[C@@H]([C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I11 compound treatment 163640.0 -21000.0 -0.56 200960.0 8310.0 0.22 -0.2378 -0.3933 3553943 ACon1_000169 CC1=CCC[C@@H]2[C@@](C)(CCc3ccoc3)[C@@H](CC[C@]21C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I12 compound treatment 187320.0 2700.0 0.07 226000.0 33300.0 0.9 0.6895 0.7613 3554710 ACon1_000170 COC(=O)c1cc(O)cc(OC)c1Oc2cc(C)cc(O)c2C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I13 compound treatment 178640.0 -5980.0 -0.16 185800.0 -6850.0 -0.19 -0.2443 -0.9973 3559593 ACon1_000171 COc1ccc(cc1)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I14 compound treatment 192120.0 7500.0 0.2 175680.0 -17000.0 -0.46 -0.183 -0.3651 3553879 ACon1_000172 CC1(C)O[C@H]2CC(=O)OC[C@]23C4CC[C@@]5(C)[C@@H](OC(=O)[C@H]6O[C@]65[C@]4(C)C(=O)C(=C13)O)c7ccoc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I15 compound treatment 170480.0 -14100.0 -0.38 186520.0 -6130.0 -0.17 -0.3848 -0.9317 1032910 ACon1_000173 COc1ccc2OC(CC(=O)c2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I16 compound treatment 192680.0 8060.0 0.22 183960.0 -8690.0 -0.24 -0.0139 -0.0437 1362 ACon1_000174 COc1c2occc2cc3ccc(=O)oc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I17 compound treatment 154480.0 -30100.0 -0.81 166800.0 -25900.0 -0.7 -1.065 -0.9975 1568908 ACon1_000175 COc1cccc2oc(cc(=O)c12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I18 compound treatment 148640.0 -36000.0 -0.96 151800.0 -40900.0 -1.11 -1.4626 -0.9976 1498810 ACon1_000176 CC(=CCOc1c2ccoc2cc3oc(=O)ccc13)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I19 compound treatment 195680.0 11100.0 0.3 210080.0 17400.0 0.47 0.5428 0.9747 1913676 ACon1_000177 COc1ccc(cc1)C(=O)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I20 compound treatment 215560.0 30900.0 0.83 238160.0 45500.0 1.23 1.4564 0.9813 3559840 ACon1_000178 COc1cc2oc(=O)ccc2c(OC)c1CC(O)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I21 mock treatment 188920.0 4300.0 0.12 187200.0 -5450.0 -0.15 -0.023 -0.1231 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I22 mock treatment 194360.0 9740.0 0.26 218920.0 26300.0 0.71 0.6871 0.9072 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I23 compound treatment 207600.0 23000.0 0.61 200200.0 7550.0 0.2 0.5791 0.894 1539 ACon1_000179 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 I24 compound treatment 202960.0 18300.0 0.49 245480.0 52800.0 1.43 1.3582 0.8983 3559836 ACon1_000180 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O)[C@]3(C)CO)[C@H](O)[C@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J01 compound treatment 218040.0 33400.0 0.89 235560.0 42900.0 1.16 1.4535 0.9916 3557805 ACon1_000181 CC1=CC(CC2(C)OC2COc3c4occc4cc5ccc(=O)oc35)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J02 compound treatment 180000.0 -4620.0 -0.12 176240.0 -16400.0 -0.44 -0.4016 -0.8707 3559624 ACon1_000182 COc1ccc(cc1)C2CC(=O)Oc3cc(O)cc(O)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J03 compound treatment 191600.0 6980.0 0.19 203760.0 11100.0 0.3 0.3447 0.9737 3559225 ACon1_000183 CC(=O)OCC(=C)[C@@H]1Cc2cc(ccc2O1)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J04 compound treatment 178120.0 -6500.0 -0.17 212920.0 20300.0 0.55 0.2651 0.4605 2060480 ACon1_000184 Oc1ccc(cc1)C2CC(=O)c3ccccc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J05 mock treatment 192000.0 7380.0 0.2 181920.0 -10700.0 -0.29 -0.0659 -0.1875 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J06 mock treatment 183680.0 -939.0 -0.03 199520.0 6870.0 0.19 0.1137 0.6061 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J07 compound treatment 201120.0 16500.0 0.44 191640.0 -1010.0 -0.03 0.2927 0.6619 3559346 ACon1_000185 C[C@H]1[C@H]2[C@H](CC3C4C[C@H](OC5OC(C)C(O)C(O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)C5O)C7C[C@@H](O)CC[C@]7(C)C4CC[C@]23C)OC81OCC(C)CC8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J08 compound treatment 188360.0 3740.0 0.1 185920.0 -6730.0 -0.18 -0.0581 -0.2795 3614341 ACon1_000186 COc1c2C(=O)OCc2c(C)c3OC4(C)CC5(O)OCC6(C)OC7(CCC(C)(C4Cc13)C65O7)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J09 compound treatment 187720.0 3100.0 0.08 190480.0 -2170.0 -0.06 0.0171 0.1677 3554184 ACon1_000187 CCC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC3CCC(O3)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J10 compound treatment 189240.0 4620.0 0.12 193960.0 1310.0 0.04 0.1124 0.8744 3557772 ACon1_000188 COc1cc(OC)c2ccc(=O)oc2c1CC(O)C(C)(C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J11 compound treatment 215800.0 31200.0 0.83 219520.0 26900.0 0.73 1.1041 0.9977 3199169 ACon1_000189 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J12 compound treatment 188200.0 3580.0 0.1 214000.0 21300.0 0.58 0.4764 0.8132 3557412 ACon1_000190 Oc1ccc(/C=C\NC=O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J13 compound treatment 20040.0 -165000.0 -4.4 19080.0 -174000.0 -4.7 -6.4356 -0.9995 3552568 ACon1_000191 C[C@@H](C1CC[C@H]2C3C[C@H]4O[C@]45[C@@H](O)C=CC(=O)[C@]5(C)C3CC[C@]12C)C6CC(=C(CO)C(=O)O6)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J14 compound treatment 245400.0 60800.0 1.63 226040.0 33400.0 0.9 1.7888 0.9616 3614342 ACon1_000192 O[C@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J15 compound treatment 109280.0 -75300.0 -2.02 144600.0 -48100.0 -1.3 -2.3449 -0.9776 3557791 ACon1_000193 CC(=CCc1c2OC(CC(=O)c2c(O)c3C=CC(C)(C)Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J16 compound treatment 181120.0 -3500.0 -0.09 155920.0 -36700.0 -0.99 -0.7694 -0.7702 3557677 ACon1_000194 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O[C@@H]8OC[C@](O)(CO)[C@H]8O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J17 compound treatment 186160.0 1540.0 0.04 216400.0 23700.0 0.64 0.4837 0.7509 3558159 ACon1_000195 COc1cc(ccc1O)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J18 compound treatment 16080.0 -169000.0 -4.51 15920.0 -177000.0 -4.78 -6.571 -0.9996 3557646 ACon1_000196 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@H](O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC[C@@]78OC[C@@]9(CCC(C)(C)CC98)[C@H](O)C[C@]76C)C4(C)C)[C@@H]3O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J19 compound treatment 191960.0 7340.0 0.2 199600.0 6950.0 0.19 0.2718 0.9998 3559382 ACon1_000197 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3ccc(O)cc3)[C@H](O)[C@@H](OC(=O)c4ccc(O)cc4)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J20 compound treatment 186120.0 1500.0 0.04 210960.0 18300.0 0.5 0.3788 0.7619 3557547 ACon1_000198 CC(OC1OC(CO)C(O)C(O)C1O)/C=C/C2(O)C(C)CC(=O)CC2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J21 mock treatment 224240.0 39600.0 1.06 207760.0 15100.0 0.41 1.0386 0.9143 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J22 mock treatment 189600.0 4980.0 0.13 221280.0 28600.0 0.78 0.6422 0.8167 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J23 compound treatment 207120.0 22500.0 0.6 207640.0 15000.0 0.41 0.7125 0.9816 3559530 ACon1_000199 C[C@H]1C[C@@H]2O[C@@]31CCC(=C3[C@H]4OC(=O)C(=C)[C@@H]24)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 J24 compound treatment 210160.0 25500.0 0.68 235160.0 42500.0 1.15 1.2968 0.969 3557731 ACon1_000200 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc3occ(c4ccc(O)cc4)c(=O)c13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K01 compound treatment 228840.0 44200.0 1.18 218360.0 25700.0 0.7 1.3285 0.968 3558170 ACon1_000201 C/C/1=C\CC\C(=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](C1)OC(=O)C(=C)C(O)CO)\CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K02 compound treatment 175880.0 -8740.0 -0.23 212320.0 19700.0 0.53 0.2112 0.3632 1449 ACon1_000202 CN1[C@@H](CCC1=O)c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K03 compound treatment 97320.0 -87300.0 -2.34 96880.0 -95800.0 -2.59 -3.4846 -0.9986 3553119 ACon1_000203 C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2CC3=C(C)C(=O)C[C@@H]13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K04 compound treatment 229520.0 44900.0 1.2 195320.0 2670.0 0.07 0.9003 0.7483 3557742 ACon1_000204 CC(=CCc1cc(O)ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K05 compound treatment 108400.0 -76200.0 -2.04 99240.0 -93400.0 -2.53 -3.2298 -0.9943 3559441 ACon1_000205 COc1cc(ccc1O)c2oc3cc(O)c(OC)c(O)c3c(=O)c2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K06 compound treatment 170920.0 -13700.0 -0.37 171760.0 -20900.0 -0.57 -0.6591 -0.9779 3557579 ACon1_000206 OCC1OC(C(O)C(O)C1O)c2c(O)cc3oc(cc(=O)c3c2O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K07 mock treatment 227320.0 42700.0 1.14 186240.0 -6410.0 -0.17 0.6849 0.5928 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K08 mock treatment 193960.0 9340.0 0.25 175000.0 -17700.0 -0.48 -0.1613 -0.299 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K09 compound treatment 220080.0 35500.0 0.95 222800.0 30100.0 0.82 1.2478 0.9972 1442461 ACon1_000207 COc1ccc2c(=O)cc(oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K10 compound treatment 211040.0 26400.0 0.71 201240.0 8590.0 0.23 0.6641 0.8926 3554705 ACon1_000208 COC(=O)c1cc(O)cc(OC)c1C(=O)c2c(O)cc(C)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K11 compound treatment 38480.0 -146000.0 -3.91 20280.0 -172000.0 -4.67 -6.0639 -0.9961 3054523 ACon1_000209 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K12 compound treatment 186680.0 2060.0 0.06 192680.0 26.9 0.0 0.0395 0.7164 3559363 ACon1_000210 C/C/1=C\CC\C(=C\CC\C(=C\C2OC(=O)C(=C)C2CC1)\C)\C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K13 compound treatment 174560.0 -10100.0 -0.27 189440.0 -3210.0 -0.09 -0.2518 -0.8903 1250866 ACon1_000211 COc1ccc(cc1)C2CC(=O)c3ccccc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K14 compound treatment 201520.0 16900.0 0.45 195400.0 2750.0 0.07 0.3723 0.8125 3557490 ACon1_000212 CC12CCCC(CO)(CO)C2C(=O)CC3(CC4CCC31)CC4=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K15 mock treatment 191840.0 7220.0 0.19 224200.0 31500.0 0.85 0.7405 0.8457 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K16 mock treatment 202440.0 17800.0 0.48 192760.0 107.0 0.0 0.3391 0.7114 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K17 compound treatment 234560.0 49900.0 1.34 223840.0 31200.0 0.84 1.5416 0.9755 3559604 ACon1_000213 Oc1ccc2C(=O)/C(=C/c3ccc(O)c(O)c3)/Oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K18 compound treatment 18160.0 -166000.0 -4.45 15560.0 -177000.0 -4.79 -6.5386 -0.9993 3557612 ACon1_000214 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)[C@H](O[C@@H]3O[C@@H](C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]3OC(=O)C)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K19 compound treatment 151520.0 -33100.0 -0.89 147600.0 -45100.0 -1.22 -1.4885 -0.9876 3559756 ACon1_000215 CC(=CCC[C@](C)(O)C1CC[C@]2(C)C1CC[C@@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]32C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K20 compound treatment 205160.0 20500.0 0.55 211920.0 19300.0 0.52 0.7574 0.9997 3559323 ACon1_000216 CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)C3[C@H](O)CC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)C6CC[C@]54C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K21 compound treatment 152520.0 -32100.0 -0.86 164000.0 -28700.0 -0.78 -1.1556 -0.9987 1026747 ACon1_000217 OC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K22 compound treatment 237040.0 52400.0 1.4 243480.0 50800.0 1.38 1.9645 1.0 3559843 ACon1_000218 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K23 mock treatment 210200.0 25600.0 0.68 248440.0 55800.0 1.51 1.5518 0.9359 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 K24 mock treatment 237120.0 52500.0 1.4 220280.0 27600.0 0.75 1.5219 0.9565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L01 compound treatment 234000.0 49400.0 1.32 195320.0 2670.0 0.07 0.9851 0.7446 3526 ACon1_000219 Oc1ccc2ccc(=O)oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L02 compound treatment 25880.0 -159000.0 -4.25 16040.0 -177000.0 -4.78 -6.3834 -0.9982 3559553 ACon1_000220 C/C=C(\C)/C(=O)O[C@H]1C=C(CO)C(=O)[C@H](OC(=O)C)[C@H]1C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L03 compound treatment 19760.0 -165000.0 -4.41 17000.0 -176000.0 -4.76 -6.4807 -0.9993 3558112 ACon1_000221 COc1cc(O)cc(O)c1C(=O)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L04 compound treatment 195400.0 10800.0 0.29 210920.0 18300.0 0.49 0.5536 0.967 3559775 ACon1_000222 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@]61CC[C@@H](C)CO6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L05 compound treatment 226680.0 42100.0 1.13 230240.0 37600.0 1.02 1.5151 0.9987 2137 ACon1_000223 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L06 compound treatment 219560.0 34900.0 0.93 224640.0 32000.0 0.87 1.2732 0.9993 3559437 ACon1_000224 CC(=CC(=O)OC(C)(C)[C@H]1Oc2ccc3ccc(=O)oc3c2[C@H]1OC(=O)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L07 mock treatment 211120.0 26500.0 0.71 177240.0 -15400.0 -0.42 0.2062 0.2507 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L08 mock treatment 213360.0 28700.0 0.77 194600.0 1950.0 0.05 0.5809 0.7538 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L09 compound treatment 141280.0 -43300.0 -1.16 116920.0 -75700.0 -2.05 -2.2695 -0.9636 3559831 ACon1_000225 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L10 compound treatment 226320.0 41700.0 1.12 201480.0 8830.0 0.24 0.9577 0.8395 3558043 ACon1_000226 COc1cc(CC(CO)C(CO)Cc2ccc(O)c(OC)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L11 compound treatment 210800.0 26200.0 0.7 189000.0 -3650.0 -0.1 0.4253 0.6013 3554965 ACon1_000227 COc1cc(O)c(C(=O)O)c(c1)c2cc(O)c(O)cc2C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L12 compound treatment 199560.0 14900.0 0.4 184160.0 -8490.0 -0.23 0.12 0.2603 3180152 ACon1_000228 CC(=C)[C@@H]1CC[C@]2(COC(=O)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)C)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L13 compound treatment 224880.0 40300.0 1.08 194400.0 1750.0 0.05 0.795 0.7374 3551952 ACon1_000229 C/C(=C\1/CCC2(COC3C2)C1CCC3(O)C(=O)O)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L14 compound treatment 173040.0 -11600.0 -0.31 209200.0 16500.0 0.45 0.0978 0.1795 3557691 ACon1_000230 CC(C)C1C(OC(=O)/C=C/c2ccccc2)C3OC1CC(C)(O)C(CCC3(C)O)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L15 mock treatment 201720.0 17100.0 0.46 178920.0 -13700.0 -0.37 0.0606 0.1027 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L16 mock treatment 206040.0 21400.0 0.57 178360.0 -14300.0 -0.39 0.1316 0.1903 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L17 compound treatment 212840.0 28200.0 0.75 201800.0 9150.0 0.25 0.7089 0.8923 1029504 ACon1_000231 Oc1cc(O)c2C(=O)CC(Oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L18 compound treatment 243280.0 58700.0 1.57 227280.0 34600.0 0.94 1.7724 0.9697 3557784 ACon1_000232 O[C@H]1CO[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L19 compound treatment 215680.0 31100.0 0.83 244880.0 52200.0 1.41 1.5873 0.9679 3555882 ACon1_000233 OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L20 compound treatment 204240.0 19600.0 0.52 190440.0 -2210.0 -0.06 0.3288 0.6223 3557549 ACon1_000234 C[C@](OC(=O)/C=C/c1ccc(O)c(O)c1)([C@@H](O)CO)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L21 compound treatment 218920.0 34300.0 0.92 208880.0 16200.0 0.44 0.9594 0.9431 3559569 ACon1_000235 COC(=O)/C=C(\C)/CC[C@@H]1C(=C)CC[C@@H]2C(C)(C)CCC[C@@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L22 compound treatment 108920.0 -75700.0 -2.02 58720.0 -134000.0 -3.63 -3.9957 -0.9621 3557634 ACon1_000236 C/C=C(/C)\C(=O)OC1C(OC(=O)/C(=C\C)/C)C(C)(C)Oc2ccc3ccc(=O)oc3c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L23 mock treatment 202960.0 18300.0 0.49 199840.0 7190.0 0.19 0.4845 0.918 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 L24 mock treatment 227200.0 42600.0 1.14 211200.0 18500.0 0.5 1.1604 0.9323 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M01 compound treatment 228400.0 43800.0 1.17 209080.0 16400.0 0.44 1.1426 0.9121 3559074 ACon1_000237 COc1cc(O)c2C(=O)C[C@@H](Oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M02 compound treatment 188160.0 3540.0 0.09 193400.0 747.0 0.02 0.0813 0.8391 959 ACon1_000238 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M03 compound treatment 248320.0 63700.0 1.7 208880.0 16200.0 0.44 1.5155 0.8612 1002015 ACon1_000239 O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M04 compound treatment 195880.0 11300.0 0.3 204560.0 11900.0 0.32 0.4409 0.9994 3557491 ACon1_000240 CC12CC3(CC2C1CC34)CCC5C(CO)(CO)CC(=O)CC45C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M05 compound treatment 140840.0 -43800.0 -1.17 75920.0 -117000.0 -3.16 -3.0627 -0.9087 3559514 ACon1_000241 CC(CC[C@@]1(C)[C@H](C)CC[C@]2(C)C1CC(=O)C=C2C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M06 compound treatment 227920.0 43300.0 1.16 193040.0 387.0 0.01 0.8264 0.7135 3558910 ACon1_000242 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@](C)(CO)C5CC[C@]43C)[C@@H]2[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M07 compound treatment 185800.0 1180.0 0.03 173280.0 -19400.0 -0.52 -0.3485 -0.6633 3559317 ACon1_000243 C[C@@H]1CC[C@@H](/C=C(\C)/C(=O)O)C2=C(C)C[C@@H](OC(=O)C)[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M08 compound treatment 110320.0 -74300.0 -1.99 100760.0 -91900.0 -2.49 -3.1644 -0.9938 3552818 ACon1_000244 C[C@]1(CC[C@]2(C)CC[C@]3(C)C4=CC(=O)c5cc(O)c(O)cc5[C@]4(C)CC[C@@]3(C)[C@@H]2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M09 mock treatment 201840.0 17200.0 0.46 192560.0 -93.1 0.0 0.3239 0.7032 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M10 mock treatment 209480.0 24900.0 0.67 208240.0 15600.0 0.42 0.7686 0.9759 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M11 compound treatment 237080.0 52500.0 1.4 196680.0 4030.0 0.11 1.0694 0.7598 3553135 ACon1_000245 C[C@H]1CC[C@H](OC(=O)C)[C@H]2C(=O)c3occ(C)c3[C@@H](OC(=O)C)[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M12 compound treatment 203600.0 19000.0 0.51 227400.0 34700.0 0.94 1.0242 0.9581 3554653 ACon1_000246 COC(=O)C(=C)CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M13 mock treatment 229160.0 44500.0 1.19 197480.0 4830.0 0.13 0.9349 0.78 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M14 mock treatment 253160.0 68500.0 1.83 200800.0 8150.0 0.22 1.4524 0.7865 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M15 compound treatment 234840.0 50200.0 1.34 209720.0 17100.0 0.46 1.2766 0.8986 3551999 ACon1_000247 C/C=C(/C)\C(=O)O[C@@H]1C[C@@H](OC(=O)/C(=C\C)/C)[C@](C)(CO)C2C3[C@H](C)CC(=O)C2[C@@]31C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M16 compound treatment 222600.0 38000.0 1.02 217720.0 25100.0 0.68 1.1982 0.9808 3552704 ACon1_000248 C[C@@H]1CC[C@H](O)/C=C/C(=O)O[C@H](C)CC[C@H](O)/C=C/C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M17 compound treatment 197520.0 12900.0 0.35 206080.0 13400.0 0.36 0.5011 0.9997 1502018 ACon1_000249 COc1ccc2oc(cc(=O)c2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M18 compound treatment 215400.0 30800.0 0.82 194880.0 2230.0 0.06 0.6248 0.7569 3557806 ACon1_000250 COC(=O)C1=CO[C@@H](OC2OC(O)C(O)C(O)C2CO)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)OC(=O)/C=C/c5ccc(OC6OC(CO)C(O)C(O)C6O)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M19 compound treatment 255800.0 71200.0 1.9 216520.0 23900.0 0.65 1.8032 0.8968 1012 ACon1_000251 Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M20 compound treatment 193640.0 9020.0 0.24 198120.0 5470.0 0.15 0.2753 0.9725 3559846 ACon1_000252 OC[C@H]1O[C@@H](Oc2ccccc2/C=C/C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M21 compound treatment 203120.0 18500.0 0.49 195200.0 2550.0 0.07 0.3987 0.7979 3559747 ACon1_000253 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M22 compound treatment 198720.0 14100.0 0.38 208600.0 15900.0 0.43 0.572 0.9977 3554833 ACon1_000254 COc1cc(C)c(C(=O)O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2OC(=O)C)n3ccc(=O)[nH]c3=O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M23 compound treatment 233600.0 49000.0 1.31 220600.0 27900.0 0.76 1.4614 0.9659 3559655 ACon1_000255 COc1cc(/C=C/C(=O)OCC[N+](C)(C)C)cc(OC)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 M24 compound treatment 203520.0 18900.0 0.51 196080.0 3430.0 0.09 0.4231 0.8231 3559343 ACon1_000256 COc1ccc(/C=C/C(=O)O[C@@H]2[C@@H](CO)O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@H]2O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N01 compound treatment 247560.0 62900.0 1.68 243840.0 51200.0 1.39 2.1704 0.9953 3558015 ACon1_000257 COc1c(O)cc2OC(CC(=O)c2c1O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N02 compound treatment 236760.0 52100.0 1.39 180480.0 -12200.0 -0.33 0.7532 0.5256 3559555 ACon1_000258 COC(=O)[C@@]1(C)CCC[C@]2(C)[C@@H](CC/C(=C/C(=O)O)/C)C(=C)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N03 compound treatment 189280.0 4660.0 0.12 171680.0 -21000.0 -0.57 -0.3133 -0.539 3557706 ACon1_000259 O=C(CCCCCC/C=C/c1ccc2OCOc2c1)N3CCCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N04 compound treatment 240440.0 55800.0 1.49 211280.0 18600.0 0.5 1.4124 0.8962 1538 ACon1_000260 Oc1ccc(c(O)c1)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N05 compound treatment 242200.0 57600.0 1.54 229400.0 36700.0 0.99 1.7926 0.9776 3557638 ACon1_000261 COC(=O)c1ccccc1O[C@@H]2O[C@H](CO[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N06 compound treatment 228520.0 43900.0 1.17 215920.0 23300.0 0.63 1.2758 0.9574 3614343 ACon1_000262 CC(C)C(NC(=O)C)C(=O)O[C@H]1CCC(C)(C)[C@@H]2CC=C3C(=O)OCC3(O)[C@@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N07 compound treatment 226080.0 41500.0 1.11 210040.0 17400.0 0.47 1.117 0.9272 3553729 ACon1_000263 CC(CO)CCCC(C)(O)c1ccc(cc1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N08 compound treatment 244560.0 59900.0 1.6 184320.0 -8330.0 -0.23 0.9742 0.6017 3614345 ACon1_000264 CC1(CCOC2OC(CO)C(O)C(O)C2O)CCC3C(=CCC4C(C)(CCCC34C)C(=O)O)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N09 mock treatment 237520.0 52900.0 1.42 192040.0 -613.0 -0.02 0.9889 0.6988 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N10 mock treatment 225240.0 40600.0 1.09 203240.0 10600.0 0.29 0.971 0.8641 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N11 compound treatment 226080.0 41500.0 1.11 190480.0 -2170.0 -0.06 0.7426 0.6687 3559351 ACon1_000265 CCCCC(CCC)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N12 compound treatment 98000.0 -86600.0 -2.32 90560.0 -102000.0 -2.76 -3.5927 -0.9962 3559523 ACon1_000266 CC(=CC(=O)O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)C3CCC2=C)C1=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N13 mock treatment 218000.0 33400.0 0.89 187360.0 -5290.0 -0.14 0.5301 0.5861 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N14 mock treatment 198240.0 13600.0 0.36 194480.0 1830.0 0.05 0.2926 0.7958 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N15 compound treatment 238520.0 53900.0 1.44 191200.0 -1450.0 -0.04 0.9917 0.6876 2181 ACon1_000267 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3cc(O)c(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N16 compound treatment 192800.0 8180.0 0.22 145680.0 -47000.0 -1.27 -0.7445 -0.5769 3557681 ACon1_000268 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N17 compound treatment 201960.0 17300.0 0.46 165320.0 -27300.0 -0.74 -0.1952 -0.2236 3557477 ACon1_000269 Oc1ccc2C(=O)CC(Oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N18 compound treatment 219600.0 35000.0 0.94 169240.0 -23400.0 -0.63 0.2134 0.1889 270 ACon1_000270 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N19 compound treatment 212000.0 27400.0 0.73 190600.0 -2050.0 -0.06 0.4786 0.6516 3558281 ACon1_000271 CC(C)C(O)CC(C)O[C@@H]1O[C@H](CO[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N20 compound treatment 171200.0 -13400.0 -0.36 173280.0 -19400.0 -0.52 -0.6247 -0.9829 3553516 ACon1_000272 CC(C)C(=O)O[C@@H]1C[C@@]2(C)O[C@](O)(C[C@@H]2O)[C@@H](C)C[C@H]3OC(=O)C(=C)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N21 compound treatment 209600.0 25000.0 0.67 194360.0 1710.0 0.05 0.5052 0.7542 3559609 ACon1_000273 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O[C@@H]5O[C@H](CO)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O[C@H]6CC[C@@]7(C)C(CC[C@]8(C)C7CC[C@@]9%10OC[C@@]%11(CCC(C)(C)CC%11%10)[C@H](O)C[C@]98C)C6(C)C)O[C@@H]3C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N22 compound treatment 199040.0 14400.0 0.39 206080.0 13400.0 0.36 0.5298 0.9996 3552601 ACon1_000274 C[C@@H](CC[C@H]1C(=CC(=O)C2C(C)(C)CCC[C@]12C)C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N23 compound treatment 241120.0 56500.0 1.51 234120.0 41500.0 1.12 1.8625 0.9893 1307633 ACon1_000275 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 N24 compound treatment 242120.0 57500.0 1.54 238920.0 46300.0 1.25 1.9733 0.9948 3557790 ACon1_000276 CC1CCC(=O)C2(O)CC(=O)C3C(C3(C)C)C12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O01 compound treatment 243560.0 58900.0 1.58 234840.0 42200.0 1.14 1.9224 0.9875 3559471 ACon1_000277 C[C@@]12CCCC(=C)[C@@H]2C[C@@](O)(CC1)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O02 compound treatment 22760.0 -162000.0 -4.33 17360.0 -175000.0 -4.75 -6.4171 -0.999 3185117 ACon1_000278 CC(=O)O[C@H]1CC[C@]2(C=O)[C@H]3CC[C@]4(C)[C@H](CC[C@]4(O)[C@@H]3CC[C@]2(O)C1)C5=CC(=O)OC5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O03 compound treatment 205000.0 20400.0 0.55 217520.0 24900.0 0.67 0.8615 0.9945 2069231 ACon1_000279 CC(=CCc1cc(ccc1O)C(=O)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O04 compound treatment 199240.0 14600.0 0.39 208800.0 16100.0 0.44 0.5857 0.9985 2091975 ACon1_000280 C/C=C/C=C/[C@H]1Cc2cc(O)cc(O)c2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O05 compound treatment 257680.0 73100.0 1.95 194320.0 1670.0 0.05 1.4138 0.7232 3559534 ACon1_000281 CC1C[C@@H]2OC(=O)C(=C)C2C[C@]34O[C@]4(C)CCC13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O06 compound treatment 236000.0 51400.0 1.37 243720.0 51100.0 1.38 1.9494 1.0 3614346 ACon1_000282 O[C@@H]1C[C@](C[C@@H](O)[C@H]1O)(OC(=O)/C=C/c2ccc(O)c(O)c2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O07 compound treatment 204760.0 20100.0 0.54 194840.0 2190.0 0.06 0.4228 0.7801 3558551 ACon1_000283 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)OC8OC(CO)C(O)C(O)C8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O08 compound treatment 238520.0 53900.0 1.44 204200.0 11500.0 0.31 1.2405 0.8409 1000088 ACon1_000284 OC1C(Oc2cc(O)cc(O)c2C1=O)c3cc(O)c(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O09 compound treatment 231080.0 46500.0 1.24 217400.0 24700.0 0.67 1.3525 0.958 3559591 ACon1_000285 C[C@@]1(O)C[C@@]2(CC1CC[C@H]23)CCC4C(C)(C)[C@H](CC[C@@]34C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O10 compound treatment 240320.0 55700.0 1.49 195840.0 3190.0 0.09 1.1146 0.7468 3554190 ACon1_000286 CCC/C=C/C=C/C1C[C@@H](O)[C@@H](O)C(=O)[C@H]1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O11 mock treatment 218720.0 34100.0 0.91 204560.0 11900.0 0.32 0.8729 0.9023 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O12 mock treatment 232040.0 47400.0 1.27 197640.0 4990.0 0.14 0.9924 0.778 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O13 compound treatment 139680.0 -44900.0 -1.2 135880.0 -56800.0 -1.54 -1.9368 -0.9926 3069775 ACon1_000287 CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O14 compound treatment 49080.0 -136000.0 -3.63 37000.0 -156000.0 -4.21 -5.5433 -0.9972 3557505 ACon1_000288 CC(C)C(O)C(=O)O[C@H]/1C\C=C(/C)\C[C@@H](OC(=O)/C(=C/CO)/CO)[C@@H]2[C@H](OC(=O)C2=C)/C=C1/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O15 compound treatment 220160.0 35500.0 0.95 172040.0 -20600.0 -0.56 0.2776 0.2519 3559563 ACon1_000289 CC1=CC(=O)[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1CC[C@@](C)(O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O16 compound treatment 252760.0 68100.0 1.82 235040.0 42400.0 1.15 2.1003 0.9751 3559243 ACon1_000290 COc1cc(cc(OC)c1O)C2C(CO)C(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)Cc4cc(OC)c(O)c(OC)c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O17 compound treatment 31920.0 -153000.0 -4.08 17840.0 -175000.0 -4.73 -6.2347 -0.9973 3559643 ACon1_000291 OC(CCc1ccccc1)CC(=O)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O18 compound treatment 228680.0 44100.0 1.18 186680.0 -5970.0 -0.16 0.719 0.6044 3559322 ACon1_000292 CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)C3[C@H](O)CC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)C6CC[C@]54C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O19 compound treatment 255800.0 71200.0 1.9 219200.0 26500.0 0.72 1.8545 0.9113 1071301 ACon1_000293 COc1ccc2CC(=O)c3cc4OCOc4cc3CCN(C)Cc2c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O20 compound treatment 224000.0 39400.0 1.05 243400.0 50700.0 1.37 1.7163 0.9914 3557261 ACon1_000294 OC(=O)CCC(=O)Cc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O21 compound treatment 215680.0 31100.0 0.83 214040.0 21400.0 0.58 0.9969 0.9844 1010377 ACon1_000295 Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O22 compound treatment 66800.0 -118000.0 -3.15 16440.0 -176000.0 -4.77 -5.6017 -0.9797 3557778 ACon1_000296 C/C(=C\CO)/CC[C@H]1C(=C)CCC2[C@@](C)(CO)CCC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O23 compound treatment 229920.0 45300.0 1.21 222360.0 29700.0 0.8 1.4255 0.9802 2080073 ACon1_000297 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 O24 compound treatment 260360.0 75700.0 2.03 234840.0 42200.0 1.14 2.2402 0.9632 3559339 ACon1_000298 COc1c(O)c2c(=O)c(coc2cc1O[C@@H]3O[C@H](CO[C@H]4OC[C@](O)(CO)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)c5ccc(O)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P01 compound treatment 255800.0 71200.0 1.9 233320.0 40700.0 1.1 2.1248 0.9661 3554303 ACon1_000299 CCCCCCCCCC[C@H](C(=O)O)[C@@]1(CCC(=O)O1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P02 compound treatment 246080.0 61500.0 1.64 250480.0 57800.0 1.57 2.2695 0.9997 3553173 ACon1_000300 CC(=C)[C@@H]1CC[C@](C)(O)[C@H](C1)OC(=O)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P03 compound treatment 237520.0 52900.0 1.42 214480.0 21800.0 0.59 1.4184 0.925 3557492 ACon1_000301 CC12CC3(CC2C1CC34)CCC5C(CO)(CO)CC(O)CC45C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P04 compound treatment 232840.0 48200.0 1.29 208360.0 15700.0 0.43 1.2127 0.8929 3554488 ACon1_000302 CN1CC(C=C2[C@H]1Cc3c[nH]c4cccc2c34)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C5=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P05 compound treatment 248000.0 63400.0 1.7 216800.0 24100.0 0.65 1.6611 0.9142 3558904 ACon1_000303 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(CO)(CO)C5CC[C@]43C)C2[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P06 compound treatment 244600.0 60000.0 1.6 207920.0 15300.0 0.41 1.4268 0.8611 3614348 ACon1_000304 COc1cc(O)c2C(=O)OC(O)(CO)C(C)c2c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P07 compound treatment 142360.0 -42300.0 -1.13 122760.0 -69900.0 -1.89 -2.1373 -0.9697 3557880 ACon1_000305 COc1cc(OC)cc(/C=C/c2ccc(O)cc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P08 compound treatment 231120.0 46500.0 1.24 188480.0 -4170.0 -0.11 0.7996 0.6402 3614349 ACon1_000306 CC(=CCC/C(=C/CC/C(=C/Cc1c(O)cc2C(=O)N(Cc2c1O)C(CCC(=O)O)C(=O)O)/C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P09 compound treatment 251800.0 67200.0 1.8 208880.0 16200.0 0.44 1.5813 0.8548 3559304 ACon1_000307 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](OC(=O)C)[C@H]4O)c(oc3c2)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P10 compound treatment 257440.0 72800.0 1.95 201440.0 8790.0 0.24 1.5456 0.7876 3559823 ACon1_000308 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](OC6OC[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P11 mock treatment 277080.0 92500.0 2.47 205760.0 13100.0 0.35 1.9997 0.8004 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P12 mock treatment 240360.0 55700.0 1.49 222440.0 29800.0 0.81 1.6245 0.9584 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P13 compound treatment 244920.0 60300.0 1.61 220520.0 27900.0 0.75 1.674 0.9401 3559341 ACon1_000309 O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3ccc(/C=C/c4cc(O)cc(O)c4)cc3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P14 compound treatment 19400.0 -165000.0 -4.42 13800.0 -179000.0 -4.84 -6.5488 -0.999 3557710 ACon1_000310 CO[C@@H]1[C@H](O)[C@@H](O[C@H]2C[C@@H](O)[C@@]3(C)[C@H](CC[C@@H]4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)O[C@H](C)[C@@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P15 compound treatment 239560.0 54900.0 1.47 212480.0 19800.0 0.54 1.4187 0.9068 3559388 ACon1_000311 COc1cc2occ(c3ccc(O[C@@H]4O[C@H](CO[C@@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3)c(=O)c2c(O)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P16 compound treatment 13600.0 -171000.0 -4.57 10000.0 -183000.0 -4.94 -6.7312 -0.9992 3557667 ACon1_000312 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@@H](C[C@@H](O)[C@]5(C)C4CC[C@]23C)O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)O[C@@]81CCC(=C)CO8 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P17 compound treatment 231640.0 47000.0 1.26 210280.0 17600.0 0.48 1.2268 0.912 3614351 ACon1_000313 O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H]1OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P18 compound treatment 100320.0 -84300.0 -2.25 42880.0 -150000.0 -4.05 -4.4616 -0.9616 3552822 ACon1_000314 C[C@]1(CCC[C@]2(C)[C@@H]1CC[C@]3(C[C@@H]4CC=C32)CC4=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P19 compound treatment 221520.0 36900.0 0.99 197200.0 4550.0 0.12 0.785 0.7892 3557267 ACon1_000315 NC(=O)Cc1ccc(O)c(Cl)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P20 compound treatment 225040.0 40400.0 1.08 215680.0 23000.0 0.62 1.2053 0.9658 3557599 ACon1_000316 C[C@H]1CCC(CC=C1CCC(=O)C)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P21 compound treatment 41960.0 -143000.0 -3.82 17960.0 -175000.0 -4.73 -6.0425 -0.9943 3614352 ACon1_000317 COc1ccc(cc1)C(=O)O[C@H]2CC(=CCC3(C)CC[C@@](O)(C(C)C)[C@H]23)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P22 compound treatment 228160.0 43500.0 1.16 234360.0 41700.0 1.13 1.622 0.9999 3557663 ACon1_000318 C[C@@H](CC[C@H]1[C@](C)(O)CCC2C(C)(C)CCC[C@]12C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P23 compound treatment 233040.0 48400.0 1.3 223680.0 31000.0 0.84 1.5098 0.978 1113986 ACon1_000319 O=c1cccc2C3CNCC(C3)Cn21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2290 P24 compound treatment 214760.0 30100.0 0.81 225520.0 32900.0 0.89 1.1993 0.9988 3557792 ACon1_000320 C/C=C(\C)/C(=O)O[C@H]1C[C@@H]2O[C@]2(C)[C@@H]3[C@H]4OC(=O)C(=C)[C@@H]4C[C@@H](O)[C@@]13C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A01 compound treatment 251120.0 59300.0 1.59 230880.0 40100.0 1.08 1.8893 0.9828 3557665 ACon1_000321 COc1cc(O)c2c(=O)c(OC)c(oc2c1)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A02 compound treatment 242400.0 50600.0 1.35 241320.0 50500.0 1.37 1.9243 1.0 3558065 ACon1_000322 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A03 compound treatment 219200.0 27400.0 0.73 223760.0 33000.0 0.89 1.1493 0.9953 3557987 ACon1_000323 COc1ccc(cc1)c2coc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(O)c3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A04 compound treatment 227320.0 35500.0 0.95 209640.0 18800.0 0.51 1.0326 0.9574 3558147 ACon1_000324 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8OC[C@H](O)[C@H](O)[C@H]8O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A05 compound treatment 205080.0 13300.0 0.36 216720.0 25900.0 0.7 0.7475 0.9504 3558051 ACon1_000325 COc1cc2ccc(=O)oc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A06 compound treatment 179320.0 -12500.0 -0.33 173480.0 -17300.0 -0.47 -0.5675 -0.986 3558231 ACon1_000326 COc1cc(O)c2c(=O)c(OC)c(oc2c1)c3cc(O)c(OC)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A07 compound treatment 183640.0 -8150.0 -0.22 190320.0 -488.0 -0.01 -0.1634 -0.7486 3558131 ACon1_000327 OCC1OC(Oc2cc(O)cc(/C=C/c3ccccc3)c2)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A08 compound treatment 12880.0 -179000.0 -4.79 14440.0 -176000.0 -4.77 -6.7601 -1.0 3553198 ACon1_000328 CC(=CCc1cc(cc(CC=C(C)C)c1O)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A09 compound treatment 193160.0 1370.0 0.04 193400.0 2590.0 0.07 0.0756 0.9543 3558232 ACon1_000329 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@H](CC[C@@H]31)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A10 compound treatment 207040.0 15300.0 0.41 190440.0 -368.0 -0.01 0.2814 0.6897 3553751 ACon1_000330 CC(O)C(O)/C=C/C=C/C(=O)O[C@@H]1C=C2COC(=O)[C@]2(O)[C@@]3(C)CCCC(C)(C)C13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A11 compound treatment 179960.0 -11800.0 -0.32 190080.0 -728.0 -0.02 -0.2376 -0.7497 3614354 ACon1_000331 CCCCCCCC(=O)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@](O)(CC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A12 compound treatment 193840.0 2050.0 0.05 196400.0 5590.0 0.15 0.1459 0.9058 3614356 ACon1_000332 COc1c(O)cc2C(O)C(C)OC(=O)c3c(O)c(OC)c(O)c(O)c3C(O)C(C)OC(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A13 mock treatment 222280.0 30500.0 0.82 191640.0 833.0 0.02 0.5927 0.7264 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A14 mock treatment 216240.0 24500.0 0.65 194160.0 3350.0 0.09 0.5267 0.7976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A15 compound treatment 205680.0 13900.0 0.37 183680.0 -7130.0 -0.19 0.1263 0.3017 3553760 ACon1_000333 CC(O)CCCCC(C(=O)O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A16 compound treatment 261720.0 69900.0 1.87 253440.0 62600.0 1.7 2.5217 0.9988 3559671 ACon1_000334 CC(CCOC(=O)C)CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A17 compound treatment 152080.0 -39700.0 -1.06 161280.0 -29500.0 -0.8 -1.3163 -0.9902 3559515 ACon1_000335 COC(=O)/C=C(\C)/CCC1(C)C(C)CCC2(C)C1CC(=O)C=C2C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A18 compound treatment 113600.0 -78200.0 -2.09 101240.0 -89600.0 -2.42 -3.1935 -0.9973 2082296 ACon1_000336 O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A19 compound treatment 15400.0 -176000.0 -4.72 12400.0 -178000.0 -4.83 -6.7515 -0.9999 3553961 ACon1_000337 CC1CC(=O)C2=C(C1)C(Cl)C(O)C3(O)C(O)c4c(O)cccc4C(=O)C23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A20 compound treatment 218320.0 26500.0 0.71 207960.0 17200.0 0.46 0.8302 0.9789 3557551 ACon1_000338 COc1c(OC2OC(CO)C(O)C(O)C2O)cc(O)c3C(=O)CC(Oc13)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A21 compound treatment 178720.0 -13100.0 -0.35 190280.0 -528.0 -0.01 -0.2573 -0.7354 3557759 ACon1_000339 C[C@@H]1CC[C@]2(C)CC[C@]3(CO)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@H]1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A22 compound treatment 239360.0 47600.0 1.27 196640.0 5830.0 0.16 1.0114 0.7888 3557801 ACon1_000340 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](O[C@@H]3[C@@H](O)[C@H](C)O[C@@H](OC/C(=C/CC/C(=C/CC/C(=C/CCC(C)(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C=C)/C)/C)/C)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A23 compound treatment 216920.0 25100.0 0.67 206800.0 16000.0 0.43 0.7815 0.9774 3557890 ACon1_000341 COc1cc(cc(OC)c1OC)C(=O)OC2OC(CO)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 A24 compound treatment 240840.0 49100.0 1.31 223520.0 32700.0 0.89 1.554 0.9817 3558223 ACon1_000342 COc1cc(O)cc(OC)c1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B01 compound treatment 228280.0 36500.0 0.98 229400.0 38600.0 1.04 1.429 0.9994 3559333 ACon1_000343 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)/C(=C\C)/C1CC(=O)OCC3C(C)C(CC3C(CO)CO)OC(=O)CC4\C(=C\C)\C(OC5OC(CO)C(O)C(O)C5O)OC=C4C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B02 compound treatment 233440.0 41700.0 1.11 209120.0 18300.0 0.5 1.1384 0.9335 3559681 ACon1_000344 CC(=O)OC[C@]12CCC[C@]3(C)[C@@H]2[C@@H](OC1=O)[C@H](OC(=O)C)[C@]4(C[C@H]5CC[C@H]43)CC5=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B03 compound treatment 215440.0 23700.0 0.63 239560.0 48800.0 1.32 1.3806 0.9433 3557417 ACon1_000345 C[C@H]1[C@H](O)CCC2=CC(=O)C(=C[C@]12C)C(C)(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B04 compound treatment 238480.0 46700.0 1.25 201520.0 10700.0 0.29 1.0882 0.8487 3559419 ACon1_000346 COC(=O)/C=C/c1ccc(OC)c(/C=C/C(C)(C)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B05 compound treatment 224760.0 33000.0 0.88 205760.0 15000.0 0.4 0.9099 0.9376 3559255 ACon1_000347 COc1c(O)c2c(=O)cc(oc2cc1O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B06 compound treatment 14960.0 -177000.0 -4.73 16440.0 -174000.0 -4.72 -6.6825 -1.0 3555950 ACon1_000348 Oc1cccc(C(=O)NCC[C@@H](CNC(=O)c2cccc(O)c2O)NC(=O)c3cccc(O)c3O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B07 compound treatment 192080.0 292.0 0.01 188240.0 -2570.0 -0.07 -0.0436 -0.6237 3555286 ACon1_000349 COc1ccc2[C@H](C)[C@H]3N(CCc4cc(OC)c(OC)cc34)Cc2c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B08 compound treatment 207040.0 15300.0 0.41 195080.0 4270.0 0.12 0.3703 0.8732 715 ACon1_000350 COc1c2ccoc2c(OC)c3oc(C)cc(=O)c13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B09 compound treatment 179360.0 -12400.0 -0.33 176520.0 -14300.0 -0.39 -0.5086 -0.9972 3559310 ACon1_000351 COc1cc(O)c2c(=O)c(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)c(oc2c1)c5ccc(O)c(O)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B10 compound treatment 184840.0 -6950.0 -0.19 190840.0 32.5 0.0 -0.1308 -0.7038 3555614 ACon1_000352 O[C@@H]1CO[C@@H](OC[C@H]2O[C@@H](Oc3cccc4cc5COC(=O)c5c(O)c34)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B11 compound treatment 79640.0 -112000.0 -3.0 83880.0 -107000.0 -2.89 -4.1681 -0.9998 1352 ACon1_000353 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B12 compound treatment 205040.0 13300.0 0.35 193480.0 2670.0 0.07 0.3018 0.8342 3552679 ACon1_000354 C[C@@H]1CC(=O)[C@]2(COC(=O)C)[C@H](CC[C@H](OC(=O)C)[C@@]32CO3)[C@]41C[C@H](OC4=O)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B13 mock treatment 213120.0 21300.0 0.57 183360.0 -7450.0 -0.2 0.2609 0.4311 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B14 mock treatment 209040.0 17300.0 0.46 198520.0 7710.0 0.21 0.474 0.9357 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B15 compound treatment 160120.0 -31700.0 -0.85 166160.0 -24600.0 -0.67 -1.0708 -0.993 3559749 ACon1_000355 CC(C)CC(=O)O[C@@H]1C/C(=C\CC\C(=C\[C@H]2OC(=O)C(=C)C21)\C)/C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B16 compound treatment 195400.0 3610.0 0.1 202640.0 11800.0 0.32 0.2948 0.8812 3554812 ACon1_000356 COc1cc(/C=C/C(=O)O[C@H]2C[C@H]3[C@@H]([C@H]2C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B17 compound treatment 215640.0 23900.0 0.64 214280.0 23500.0 0.64 0.9005 1.0 3559769 ACon1_000357 COc1cc(/C=C/2\Oc3cc(O)cc(O)c3C2=O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B18 compound treatment 198400.0 6610.0 0.18 196560.0 5750.0 0.16 0.2352 0.998 3557998 ACon1_000358 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)/C=C/c6ccccc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B19 compound treatment 11360.0 -180000.0 -4.83 12280.0 -179000.0 -4.83 -6.8302 -1.0 3559817 ACon1_000359 COc1c(CC=C(C)C)cc(cc1CC=C(C)C)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B20 compound treatment 155600.0 -36200.0 -0.97 156120.0 -34700.0 -0.94 -1.3485 -0.9999 3554713 ACon1_000360 COC(=O)c1cc(OC)cc(OC)c1C(=O)c2coc(/C=C/C)c(OC)c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B21 compound treatment 83040.0 -109000.0 -2.91 53000.0 -138000.0 -3.73 -4.695 -0.9924 3553590 ACon1_000361 CC(C)C1CCC2(C)CCC(O)C(C)(O)C2C1OC(=O)/C=C/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B22 compound treatment 212400.0 20600.0 0.55 182200.0 -8610.0 -0.23 0.2251 0.376 3558127 ACon1_000362 OCC1OC(OC2OC=CC3(O)C(OC(=O)c4ccc(O)cc4)C=C(CO)C23)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B23 compound treatment 197120.0 5330.0 0.14 196160.0 5350.0 0.14 0.2033 1.0 3553394 ACon1_000363 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 B24 compound treatment 113840.0 -77900.0 -2.09 98840.0 -92000.0 -2.49 -3.2349 -0.9961 3553902 ACon1_000364 CC1=C(C)C(=O)O[C@@H](C1)[C@](C)(O)C2(O)CC[C@@]3(O)[C@@H]4CC=C5CC=CC(=O)[C@]5(C)C4CC[C@]23C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C01 compound treatment 212320.0 20500.0 0.55 201400.0 10600.0 0.29 0.5911 0.9541 3557813 ACon1_000365 OC1COC(Oc2cc(O)c3C[C@H](O)[C@H](Oc3c2)c4ccc(O)c(O)c4)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C02 compound treatment 217720.0 25900.0 0.69 231360.0 40600.0 1.1 1.2668 0.9755 3558044 ACon1_000366 OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C03 compound treatment 190440.0 -1350.0 -0.04 173120.0 -17700.0 -0.48 -0.3641 -0.7582 3557757 ACon1_000367 COc1cc(O)cc2occ(c3ccc(O)cc3)c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C04 compound treatment 203760.0 12000.0 0.32 195720.0 4910.0 0.13 0.3205 0.9242 3552816 ACon1_000368 C[C@]1(C[C@H](O)[C@@H]2[C@H](OC(=O)C2=C)[C@H]1C(=C)CO)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C05 compound treatment 172760.0 -19000.0 -0.51 176120.0 -14700.0 -0.4 -0.6411 -0.9925 3558075 ACon1_000369 OC[C@H]1O[C@@H](OCCc2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1OC(=O)/C=C/c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C06 compound treatment 205880.0 14100.0 0.38 191520.0 713.0 0.02 0.2802 0.7423 3554832 ACon1_000370 COc1cc(c(OC)cc1O)c2coc3cc(O)cc(O)c3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C07 compound treatment 205720.0 13900.0 0.37 181520.0 -9290.0 -0.25 0.0857 0.1907 3558135 ACon1_000371 COc1cc2OC(CC(=O)c2c(OC)c1C)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C08 compound treatment 190400.0 -1390.0 -0.04 174080.0 -16700.0 -0.45 -0.3465 -0.7625 3559269 ACon1_000372 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C09 compound treatment 180400.0 -11400.0 -0.3 190480.0 -328.0 -0.01 -0.2217 -0.7274 703 ACon1_000373 OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C10 compound treatment 187960.0 -3830.0 -0.1 212360.0 21600.0 0.58 0.3402 0.5742 3553121 ACon1_000374 C[C@H]1CC(=O)C2=C(C1)C(O)C(O)[C@]3(O)[C@@H](O)c4c(O)cccc4C(=O)[C@@H]23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C11 mock treatment 199400.0 7610.0 0.2 177040.0 -13800.0 -0.37 -0.1196 -0.2815 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C12 mock treatment 208960.0 17200.0 0.46 186600.0 -4210.0 -0.11 0.2443 0.5161 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C13 compound treatment 101480.0 -90300.0 -2.42 82360.0 -108000.0 -2.94 -3.7841 -0.9953 3558186 ACon1_000375 CC1=C2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3[C@H](C1)OC(=O)Cc4ccc(O)cc4)C(=CC2=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C14 compound treatment 212880.0 21100.0 0.56 179000.0 -11800.0 -0.32 0.1729 0.2666 3557399 ACon1_000376 OC1C=CC(O)C23OC13C(O)C=CC42Oc5cccc6cccc(O4)c56 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C15 mock treatment 186960.0 -4830.0 -0.13 177960.0 -12800.0 -0.35 -0.3373 -0.909 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C16 mock treatment 196360.0 4570.0 0.12 182880.0 -7930.0 -0.21 -0.0653 -0.2643 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C17 compound treatment 207560.0 15800.0 0.42 183040.0 -7770.0 -0.21 0.1496 0.3174 3553202 ACon1_000377 CC(=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C(O)CC(OC(=O)C)/C(=C/COCC(O)C(O)C(O)C(O)CO)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C18 compound treatment 184360.0 -7430.0 -0.2 176880.0 -13900.0 -0.38 -0.4071 -0.9552 3557463 ACon1_000378 COc1cc(oc(=O)c1)C2C3(O)CC4OC(=O)C3(O)C(C(=O)c5ccccc5)C2(O)C4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C19 compound treatment 19640.0 -172000.0 -4.6 19960.0 -171000.0 -4.63 -6.5266 -1.0 3558937 ACon1_000379 O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](OC(=O)c4cc(O)c(O)c(O)c4)[C@H]1OC(=O)c5cc(O)c(O)c(O)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C20 compound treatment 180880.0 -10900.0 -0.29 160880.0 -29900.0 -0.81 -0.7792 -0.9049 3552950 ACon1_000380 C[C@H]1[C@@H]2[C@H](OC(=O)C)C(=O)[C@@]3(C)[C@@H](CC[C@H]4/C(=C(\CCC=C(C)C)/C(=O)O)/[C@H](C[C@@]43C)OC(=O)C)[C@@]2(C)C=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C21 compound treatment 205400.0 13600.0 0.36 188720.0 -2090.0 -0.06 0.2175 0.5903 3557766 ACon1_000381 CC1=C2C/C=C(\C)/C(C/C=C(\C)/CC2OC1=O)OC3OC(CO)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C22 compound treatment 184040.0 -7750.0 -0.21 195800.0 4990.0 0.14 -0.051 -0.206 3559361 ACon1_000382 C[C@@H]([C@H]1CCC2C3CC=C4C[C@H](C[C@H](O)[C@]4(C)C3CC[C@]12C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C6CC(=C(CO)C(=O)O6)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C23 compound treatment 218280.0 26500.0 0.71 202080.0 11300.0 0.31 0.7169 0.9291 3553616 ACon1_000383 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C)[C@H]3C[C@H](O)[C@](O)(COC(=O)C)[C@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 C24 compound treatment 222400.0 30600.0 0.82 192840.0 2030.0 0.06 0.6179 0.7529 3558764 ACon1_000384 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(OC)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D01 compound treatment 187600.0 -4190.0 -0.11 200720.0 9910.0 0.27 0.1105 0.3801 3559335 ACon1_000385 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)/C(=C\C)/C1CC(=O)OCC(CO)C3CC(OC(=O)CC4\C(=C\C)\C(OC5OC(CO)C(O)C(O)C5O)OC=C4C(=O)OC)C(C)C3COC(=O)CC6\C(=C\C)\C(OC7OC(CO)C(O)C(O)C7O)OC=C6C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D02 compound treatment 16440.0 -175000.0 -4.69 20120.0 -171000.0 -4.62 -6.5841 -1.0 3552117 ACon1_000386 C/C=C\C(=O)O[C@@H]1C[C@H]2O[C@@H]3C=C(C)C(=O)C[C@]3(C)[C@]1(C)[C@@]42CO4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D03 compound treatment 229600.0 37800.0 1.01 218240.0 27400.0 0.74 1.2403 0.9885 3554011 ACon1_000387 CC1CCC(=C(CC/C(=C\COC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)/C)C1(C)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D04 compound treatment 245120.0 53300.0 1.43 209800.0 19000.0 0.51 1.3723 0.905 3559732 ACon1_000388 CC1=C[C@H]2OC(=O)C(=C)[C@H]2C[C@@H]3[C@H]1CC[C@@]3(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D05 compound treatment 184840.0 -6950.0 -0.19 141400.0 -49400.0 -1.34 -1.0772 -0.7977 3558877 ACon1_000389 C/C/1=C\CC\C(=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](C1)OC(=O)C(=C)CO)\CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D06 compound treatment 239560.0 47800.0 1.28 204720.0 13900.0 0.38 1.1699 0.8782 1607 ACon1_000390 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D07 compound treatment 203040.0 11300.0 0.3 203480.0 12700.0 0.34 0.4554 0.9979 3557737 ACon1_000391 CCCCCC(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D08 compound treatment 196360.0 4570.0 0.12 190920.0 113.0 0.0 0.0886 0.7245 3614357 ACon1_000392 O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D09 compound treatment 220600.0 28800.0 0.77 208000.0 17200.0 0.47 0.8741 0.9708 3559940 ACon1_000393 COc1cc(ccc1O)C2C(CO)C(CO)Cc3cc(OC)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D10 compound treatment 193400.0 1610.0 0.04 219960.0 29200.0 0.79 0.5886 0.7446 3557859 ACon1_000394 CC1(C)Oc2ccc3ccc(=O)oc3c2[C@@H](O)[C@H]1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D11 mock treatment 222360.0 30600.0 0.82 215520.0 24700.0 0.67 1.0513 0.995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D12 mock treatment 162160.0 -29600.0 -0.79 192600.0 1790.0 0.05 -0.5261 -0.6626 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D13 compound treatment 175920.0 -15900.0 -0.42 208720.0 17900.0 0.48 0.0428 0.0664 3557863 ACon1_000395 CCC(C)C(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D14 compound treatment 172000.0 -19800.0 -0.53 153760.0 -37000.0 -1.0 -1.0835 -0.9554 3558515 ACon1_000396 C[C@H]1Oc2c(C(CC(=O)O)c3ccccc3)c4OC(C)(C)C=Cc4c(O)c2C(=O)[C@H]1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D15 mock treatment 204840.0 13100.0 0.35 194960.0 4150.0 0.11 0.3264 0.8898 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D16 mock treatment 230280.0 38500.0 1.03 220880.0 30100.0 0.81 1.3037 0.9932 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D17 compound treatment 190800.0 -988.0 -0.03 192400.0 1590.0 0.04 0.0118 0.2333 3559665 ACon1_000397 CCC(C[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2C3=CC(=O)[C@H]4[C@H](C)[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)c5ccccc5)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D18 compound treatment 216040.0 24300.0 0.65 219720.0 28900.0 0.78 1.0122 0.9956 3559379 ACon1_000398 O[C@@H]1CO[C@@H](OC[C@H]2O[C@@H](OC/C=C/c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@@H](O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D19 compound treatment 209280.0 17500.0 0.47 262040.0 71200.0 1.93 1.6945 0.8539 3559700 ACon1_000399 CO[C@@H]1C[C@@]2(CC=C)[C@H](C)[C@H](OC2=C(OC)C1=O)c3ccc4OCOc4c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D20 compound treatment 218400.0 26600.0 0.71 193720.0 2910.0 0.08 0.5591 0.7807 3552828 ACon1_000400 C[C@]12CC[C@H](C[C@H]2[C@H](CCC3(O)[C@@H]4C[C@@H](CC[C@@]4(C)C=CC3=O)C(=C)C(=O)O)C(=O)C=C1)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D21 compound treatment 219320.0 27500.0 0.74 199880.0 9070.0 0.25 0.6944 0.8945 3559727 ACon1_000401 COC(=O)CC(C)CC[C@H]1C(=CC[C@H]2C(C)(C)[C@H](O)CC[C@]12C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D22 compound treatment 123120.0 -68700.0 -1.84 119920.0 -70900.0 -1.92 -2.6558 -0.9998 3558274 ACon1_000402 C[C@@H]1C[C@@H](OC(=O)C)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCC3=CC(=O)OC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D23 compound treatment 213800.0 22000.0 0.59 189720.0 -1090.0 -0.03 0.3955 0.6709 3553349 ACon1_000403 CC(=O)O[C@H]1CC(=C2[C@@H]3OC(=O)C(=C)[C@@H]3CC[C@@]2(C)C1)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 D24 compound treatment 214480.0 22700.0 0.61 241000.0 50200.0 1.36 1.39 0.934 3554883 ACon1_000404 COc1cc(ccc1O)c2cc(=O)c3c(O)c(OC)c(O)c(OC)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E01 mock treatment 201880.0 10100.0 0.27 189880.0 -928.0 -0.03 0.1731 0.6386 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E02 mock treatment 182400.0 -9390.0 -0.25 205120.0 14300.0 0.39 0.0964 0.2088 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E03 compound treatment 173920.0 -17900.0 -0.48 182160.0 -8650.0 -0.23 -0.5035 -0.9461 3557985 ACon1_000405 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](C)O[C@@H](OCC3OC(Oc4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)c(O)c6)C(O)C(O)C3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E04 compound treatment 191280.0 -508.0 -0.01 170120.0 -20700.0 -0.56 -0.4056 -0.724 3557740 ACon1_000406 COc1ccc(/C=C/C(=O)O[C@@H]2[C@@H](O)[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@H]6O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]6O)[C@@H]2OC(=O)C)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E05 compound treatment 182120.0 -9670.0 -0.26 170680.0 -20100.0 -0.54 -0.5682 -0.942 3558077 ACon1_000407 O[C@H]1[C@H](O)[C@@H](COC(=O)/C=C/c2ccc(O)c(O)c2)O[C@@H](OCCc3ccc(O)c(O)c3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E06 compound treatment 177000.0 -14800.0 -0.4 191440.0 633.0 0.02 -0.2676 -0.6759 3558242 ACon1_000408 COc1cc2c(=O)c(coc2cc1O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E07 compound treatment 203240.0 11500.0 0.31 205600.0 14800.0 0.4 0.4998 0.9912 1524104 ACon1_000409 Oc1cc(O)c2C(=O)CC(Oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E08 compound treatment 169920.0 -21900.0 -0.58 170120.0 -20700.0 -0.56 -0.8096 -0.9998 2060441 ACon1_000410 OC(=O)c1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E09 mock treatment 158440.0 -33300.0 -0.89 192480.0 1670.0 0.05 -0.5987 -0.6704 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E10 mock treatment 155560.0 -36200.0 -0.97 173480.0 -17300.0 -0.47 -1.0169 -0.9446 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E11 compound treatment 169680.0 -22100.0 -0.59 168960.0 -21800.0 -0.59 -0.8364 -1.0 3614358 ACon1_000411 C[C@H]1CCC[C@@H](O)CC(=O)c2c(O)cc(O)cc2CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E12 compound treatment 182680.0 -9110.0 -0.24 181960.0 -8850.0 -0.24 -0.3416 -1.0 3553963 ACon1_000412 CC1CC(=O)C2=C(C1)C3OC3C4(O)C(O)c5c(O)cccc5C(=O)C24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E13 compound treatment 180760.0 -11000.0 -0.29 176560.0 -14200.0 -0.39 -0.4813 -0.9912 2565 ACon1_000413 COC1=CC(=O)OC1(O)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E14 compound treatment 159680.0 -32100.0 -0.86 163000.0 -27800.0 -0.75 -1.1396 -0.9978 3554186 ACon1_000414 CCC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC3CCC(O3)C(C)C(=O)OC(C)CC4CCC(O4)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E15 compound treatment 164360.0 -27400.0 -0.73 159400.0 -31400.0 -0.85 -1.12 -0.9973 3614360 ACon1_000415 COC1CC(=O)C2(C3C(CC(C)C)NC2=O)C(C=C(C)C3C)/C=C(\C)/CCC(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E16 compound treatment 158920.0 -32900.0 -0.88 170920.0 -19900.0 -0.54 -1.0024 -0.9723 3559688 ACon1_000416 COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O)c(OC)c3)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E17 mock treatment 184720.0 -7070.0 -0.19 183800.0 -7010.0 -0.19 -0.2678 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E18 mock treatment 164160.0 -27600.0 -0.74 168080.0 -22700.0 -0.62 -0.9576 -0.9959 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E19 compound treatment 191560.0 -228.0 -0.01 165920.0 -24900.0 -0.67 -0.4807 -0.7135 3557588 ACon1_000417 CC(=CCc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(CC=C(C)C)c1C(O)C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E20 compound treatment 188320.0 -3470.0 -0.09 184680.0 -6130.0 -0.17 -0.1829 -0.9623 3557280 ACon1_000418 C[C@H]1CC/C=C(\C)/[C@@H](O)/C=C/[C@@](C)(O)\C=C\C(=O)O[C@@H]1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E21 compound treatment 179680.0 -12100.0 -0.32 172840.0 -18000.0 -0.49 -0.573 -0.9805 3557796 ACon1_000419 C/C(=C\CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C=C)/CC[C@H](O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E22 compound treatment 179520.0 -12300.0 -0.33 191640.0 833.0 0.02 -0.2161 -0.657 3554684 ACon1_000420 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](C=C)[C@@H]1C[C@H]3N(CCc4cc(O)c(O)cc34)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E23 compound treatment 192840.0 1050.0 0.03 186000.0 -4810.0 -0.13 -0.0721 -0.5417 3557854 ACon1_000421 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 E24 compound treatment 197400.0 5610.0 0.15 185120.0 -5690.0 -0.15 -0.0027 -0.0127 3559947 ACon1_000422 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C\c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F01 mock treatment 180520.0 -11300.0 -0.3 212200.0 21400.0 0.58 0.1964 0.3008 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F02 mock treatment 194760.0 2970.0 0.08 189960.0 -848.0 -0.02 0.04 0.4833 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F03 compound treatment 216360.0 24600.0 0.66 213120.0 22300.0 0.6 0.8919 0.9991 3558066 ACon1_000423 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F04 compound treatment 192600.0 812.0 0.02 221840.0 31000.0 0.84 0.6094 0.7251 3559407 ACon1_000424 CC1=C2CC([C@@H](O)CC2(C)CCC1)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F05 compound treatment 179240.0 -12500.0 -0.34 179600.0 -11200.0 -0.3 -0.4519 -0.9987 3559280 ACon1_000425 COc1cc(cc(OC)c1O)c2cc(=O)c3c(O)c(OC)c(OC)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F06 compound treatment 186000.0 -5790.0 -0.15 169920.0 -20900.0 -0.57 -0.5093 -0.8687 3555180 ACon1_000426 COc1ccc(CCc2cc(OC)cc(=O)o2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F07 compound treatment 140440.0 -51300.0 -1.37 129480.0 -61300.0 -1.66 -2.1452 -0.9956 3559863 ACon1_000427 CCC1CN2CCc3cc(OC)c(OC)cc3C2CC1CC4=NCCc5cc(OC)c(OC)cc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F08 compound treatment 29200.0 -163000.0 -4.35 36880.0 -154000.0 -4.17 -6.0219 -0.9998 3553794 ACon1_000428 CC[C@H](C)/C=C(\C)/C=C/C(=O)Cc1cc(O)c(C)c(O)c1C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F09 mock treatment 186400.0 -5390.0 -0.14 187320.0 -3490.0 -0.09 -0.1687 -0.979 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F10 mock treatment 166960.0 -24800.0 -0.66 160200.0 -30600.0 -0.83 -1.0555 -0.994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F11 compound treatment 164600.0 -27200.0 -0.73 174920.0 -15900.0 -0.43 -0.8184 -0.9686 3554484 ACon1_000429 CN1C(=O)c2ccccc2NC(=O)[C@@]31O[C@@H]3c4cccc(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F12 compound treatment 182080.0 -9710.0 -0.26 217280.0 26500.0 0.72 0.3231 0.4239 3557861 ACon1_000430 CC(=CC(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F13 compound treatment 172200.0 -19600.0 -0.52 165880.0 -24900.0 -0.67 -0.8477 -0.9922 2060491 ACon1_000431 CC(C)CC(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F14 compound treatment 141920.0 -49900.0 -1.33 143000.0 -47800.0 -1.29 -1.8584 -0.9999 3552813 ACon1_000432 C[C@@H]1Oc2c(C(CC(=O)O)c3ccccc3)c4OC(C)(C)C=Cc4c(O)c2C(=O)[C@H]1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F15 compound treatment 19400.0 -172000.0 -4.61 18640.0 -172000.0 -4.66 -6.5564 -1.0 3553624 ACon1_000433 CC(C)CC(=O)O[C@H]1C(CC2O[C@]2(C)C1=O)C(=C)C(=O)/C=C/C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F16 compound treatment 174680.0 -17100.0 -0.46 171920.0 -18900.0 -0.51 -0.6852 -0.9985 3557942 ACon1_000434 CC1CCC2(C)C(CC(=O)C=C2C)C1(C)CC/C(=C\C(=O)O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F17 mock treatment 173480.0 -18300.0 -0.49 166040.0 -24800.0 -0.67 -0.8204 -0.9881 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F18 mock treatment 171320.0 -20500.0 -0.55 155240.0 -35600.0 -0.96 -1.068 -0.9642 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F19 compound treatment 175840.0 -15900.0 -0.43 183680.0 -7130.0 -0.19 -0.4381 -0.9357 3559629 ACon1_000435 C/C=C(/C)\C(=O)O[C@H]1C[C@@](C)(O)C(=O)[C@@H](OC(=O)/C(=C\C)/C)[C@@]2(C)CC[C@@](O)(C(C)C)[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F20 compound treatment 175160.0 -16600.0 -0.44 171080.0 -19700.0 -0.53 -0.6922 -0.9959 3554672 ACon1_000436 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F21 compound treatment 134880.0 -56900.0 -1.52 134160.0 -56600.0 -1.53 -2.1608 -1.0 3559533 ACon1_000437 C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2CC3=C(C)C(=O)C[C@@H]13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F22 compound treatment 196640.0 4850.0 0.13 180280.0 -10500.0 -0.29 -0.1098 -0.3505 3558196 ACon1_000438 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccc(O)c(O)c6)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F23 compound treatment 13720.0 -178000.0 -4.76 14440.0 -176000.0 -4.77 -6.7443 -1.0 3559742 ACon1_000439 C/C=C(/C)\C(=O)O[C@H]1C=C(CO)C(=O)[C@H](OC(=O)\C(=C\CO)\C)[C@H]1C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 F24 compound treatment 155880.0 -35900.0 -0.96 197880.0 7070.0 0.19 -0.5438 -0.5552 1003829 ACon1_000440 CCCCCCC(O)CC=CCCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G01 compound treatment 208120.0 16300.0 0.44 212400.0 21600.0 0.58 0.7223 0.9897 3557821 ACon1_000441 OC[C@@]1(O)CO[C@H](OC[C@H]2O[C@@H](OC(CCCCc3ccc(O)cc3)CCc4ccc(O)cc4)[C@H](O[C@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@@H]2O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G02 compound treatment 165760.0 -26000.0 -0.7 211120.0 20300.0 0.55 -0.1035 -0.1166 1119359 ACon1_000442 COc1cc2ccc(=O)oc2c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G03 mock treatment 175280.0 -16500.0 -0.44 174120.0 -16700.0 -0.45 -0.6317 -0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G04 mock treatment 176040.0 -15700.0 -0.42 182280.0 -8530.0 -0.23 -0.4611 -0.9599 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G05 compound treatment 181400.0 -10400.0 -0.28 179040.0 -11800.0 -0.32 -0.4217 -0.9977 3557908 ACon1_000443 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G06 compound treatment 192360.0 572.0 0.02 204600.0 13800.0 0.37 0.2749 0.7355 3552802 ACon1_000444 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G07 compound treatment 169760.0 -22000.0 -0.59 169400.0 -21400.0 -0.58 -0.8264 -1.0 3558163 ACon1_000445 CC1(C)O[C@@]2(C)CC[C@@H]1CC2OC3OC(CO)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G08 compound treatment 167920.0 -23900.0 -0.64 177600.0 -13200.0 -0.36 -0.7043 -0.9625 3614356 ACon1_000446 COc1c(O)cc2C(O)C(C)OC(=O)c3c(O)c(OC)c(O)c(O)c3C(O)C(C)OC(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G09 compound treatment 172720.0 -19100.0 -0.51 172840.0 -18000.0 -0.49 -0.7046 -0.9997 1658516 ACon1_000447 CC(C)(O)C(O)COc1c2ccoc2cc3oc(=O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G10 compound treatment 178960.0 -12800.0 -0.34 179760.0 -11000.0 -0.3 -0.4541 -0.9977 3614362 ACon1_000448 CC(=CCC/C(=C/CCC1(C)Oc2c3CN(C(CCC(=O)O)C(=O)O)C(=O)c3cc(O)c2CC1O)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G11 compound treatment 163920.0 -27900.0 -0.75 170280.0 -20500.0 -0.56 -0.9201 -0.9895 3553707 ACon1_000449 CC(CCC1C(C)(O)C(=O)C=C2C(C)(C)CCCC12C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G12 compound treatment 126480.0 -65300.0 -1.75 135000.0 -55800.0 -1.51 -2.3036 -0.9974 3554773 ACon1_000450 COc1c(O)ccc2oc3c(OC)c4OC5(C)CCCC(O5)c4c(O)c3c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G13 compound treatment 183480.0 -8310.0 -0.22 152120.0 -38700.0 -1.05 -0.8977 -0.8385 3553974 ACon1_000451 CC1CC(=O)OC(C)C(O)/C=C/C(=O)OC(C)C(O)/C=C/C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G14 compound treatment 176920.0 -14900.0 -0.4 190560.0 -248.0 -0.01 -0.286 -0.7189 3555129 ACon1_000452 COc1ccc(cc1)C2(O)C(O)C(=O)Nc3ccccc32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G15 compound treatment 159120.0 -32700.0 -0.87 181280.0 -9530.0 -0.26 -0.8003 -0.8784 3557302 ACon1_000453 CC(=O)NCCc1ccc(O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G16 compound treatment 150400.0 -41400.0 -1.11 154000.0 -36800.0 -1.0 -1.4874 -0.9986 3559689 ACon1_000454 CO[C@H]1C[C@@H]2N3CC(O)[C@@]2(C=C1)c4cc5OCOc5cc4C3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G17 compound treatment 153200.0 -38600.0 -1.03 165160.0 -25600.0 -0.69 -1.2208 -0.9814 3557386 ACon1_000455 CC1CCCC2OC2C(=O)c3c(O)cc(O)cc3CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G18 compound treatment 14840.0 -177000.0 -4.73 22760.0 -168000.0 -4.55 -6.5638 -0.9998 3553155 ACon1_000456 C[C@H]1O[C@H](C[C@@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@H]2O)c3ccc4C(=O)C5=C(C=C[C@]6(O)C[C@@](C)(O)CC(=O)[C@]56O)C(=O)c4c3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G19 mock treatment 168240.0 -23500.0 -0.63 188040.0 -2770.0 -0.07 -0.4984 -0.7857 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G20 mock treatment 184040.0 -7750.0 -0.21 175200.0 -15600.0 -0.42 -0.4453 -0.9462 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G21 compound treatment 187240.0 -4550.0 -0.12 178960.0 -11800.0 -0.32 -0.3128 -0.9119 3554304 ACon1_000457 CCCCCCCCCCC1C(=O)OC(C(=O)O)C1(O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G22 compound treatment 195640.0 3850.0 0.1 167560.0 -23200.0 -0.63 -0.3722 -0.5836 1059159 ACon1_000458 COC(=O)C1=COC(C)C2CN3CCC4(C3CC21)C(=O)Nc5ccccc54 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G23 compound treatment 92480.0 -99300.0 -2.66 94480.0 -96300.0 -2.61 -3.7223 -1.0 3557966 ACon1_000459 CC(=CCc1c(O)ccc2c(=O)c(coc12)c3ccc(O)cc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 G24 compound treatment 189400.0 -2390.0 -0.06 199440.0 8630.0 0.23 0.1201 0.4957 3554685 ACon1_000460 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@H](O)C[C@]3(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H01 compound treatment 194960.0 3170.0 0.08 201520.0 10700.0 0.29 0.2651 0.8772 3559300 ACon1_000461 C[C@@H]1O[C@@H](O[C@H]2[C@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC[C@@H]6C7[C@@](C)(O)[C@@H](CC=C(C)C)O[C@@]7(O)[C@H](O)[C@]65C)C3(C)C)O[C@H](CO)[C@H](O)[C@@H]2O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H02 compound treatment 76560.0 -115000.0 -3.08 69320.0 -121000.0 -3.29 -4.5051 -0.9995 3559819 ACon1_000462 C/C=C(\C)/C(=O)O[C@@H]1C[C@@](C)(O)C(=O)C[C@@H](O)\C(=C\[C@H]2OC(=O)C(=C)[C@@H]21)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H03 mock treatment 188280.0 -3510.0 -0.09 171280.0 -19500.0 -0.53 -0.4402 -0.8198 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H04 mock treatment 185080.0 -6710.0 -0.18 225440.0 34600.0 0.94 0.5361 0.5616 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H05 compound treatment 177760.0 -14000.0 -0.38 180600.0 -10200.0 -0.28 -0.4607 -0.9887 3557937 ACon1_000463 COc1ccc(cc1)c2coc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H06 compound treatment 15400.0 -176000.0 -4.72 16440.0 -174000.0 -4.72 -6.6742 -1.0 3559369 ACon1_000464 CC(=C)C1CCC2(CCC3(C)C(CCC4C5(C)C(C=O)C(O)C(C)(C)C5CCC43C)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H07 compound treatment 164720.0 -27100.0 -0.72 177880.0 -12900.0 -0.35 -0.7594 -0.9444 3059949 ACon1_000465 CC(=O)NCCc1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H08 compound treatment 107320.0 -84500.0 -2.26 107240.0 -83600.0 -2.26 -3.1974 -1.0 3553802 ACon1_000466 CC[C@H](C)/C=C(\C)/C=C/C1=CC2=CC(=O)[C@]3(C)OC(=O)[C@H]([C@@H]3C2=CO1)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H09 compound treatment 48800.0 -143000.0 -3.82 48280.0 -143000.0 -3.86 -5.4329 -1.0 3553991 ACon1_000467 Cc1cc(O)c(Oc2cc(C)cc(O)c2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H10 compound treatment 164120.0 -27700.0 -0.74 177400.0 -13400.0 -0.36 -0.78 -0.9462 3557512 ACon1_000468 COc1cc(cc(OC)c1O)C(=O)OCC2(O)COC(OCC3OC(Oc4c(OC)cc(CO)cc4OC)C(O)C(O)C3O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H11 compound treatment 173760.0 -18000.0 -0.48 151680.0 -39100.0 -1.06 -1.09 -0.9365 3557927 ACon1_000469 CCC/C=C/1\OC(=O)C2=C1CCC(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H12 compound treatment 184560.0 -7230.0 -0.19 184920.0 -5890.0 -0.16 -0.2494 -0.9954 3558562 ACon1_000470 COc1cc2ccc(=O)oc2cc1OCC=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H13 compound treatment 170280.0 -21500.0 -0.58 165680.0 -25100.0 -0.68 -0.8878 -0.9965 3554565 ACon1_000471 COC(=O)[C@]12C(=O)C(C)C(=O)[C@]2(C)C(=C[C@H]3[C@]4(C)CC[C@H](OC(=O)C)C(C)(C)[C@H]4CC[C@@]31C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H14 compound treatment 184120.0 -7670.0 -0.21 174600.0 -16200.0 -0.44 -0.4553 -0.94 3558607 ACon1_000472 COc1c2CC(Oc2cc3oc(CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(=O)c13)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H15 compound treatment 169160.0 -22600.0 -0.61 175360.0 -15400.0 -0.42 -0.7237 -0.9837 3555928 ACon1_000473 Oc1cc2O/C(=C\c3cc(O)c(O)c(O)c3)/C(=O)c2c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H16 compound treatment 157200.0 -34600.0 -0.93 174240.0 -16600.0 -0.45 -0.9714 -0.9447 3554273 ACon1_000474 CCCCCC[C@H](O)[C@@H]1C[C@@H](O)C2=C(O1)[C@@H](O)CCC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H17 compound treatment 76440.0 -115000.0 -3.09 77360.0 -113000.0 -3.07 -4.3535 -1.0 3554214 ACon1_000475 CCCC#CC#CCCCCCCCCCCC(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H18 compound treatment 168680.0 -23100.0 -0.62 139680.0 -51100.0 -1.38 -1.4158 -0.934 3554824 ACon1_000476 COc1cc(=O)oc(c1C)[C@@]2(C)O[C@H]2/C(=C\C(=C\[C@@]3(C)O[C@@H](C)[C@]4(C)OC43)\C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H19 mock treatment 178360.0 -13400.0 -0.36 173840.0 -17000.0 -0.46 -0.5788 -0.9926 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H20 mock treatment 165520.0 -26300.0 -0.7 171200.0 -19600.0 -0.53 -0.8722 -0.9904 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H21 compound treatment 177840.0 -13900.0 -0.37 171200.0 -19600.0 -0.53 -0.6392 -0.9851 3559440 ACon1_000477 COc1c(OC)c2c(C)cccc2oc1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H22 compound treatment 13960.0 -178000.0 -4.76 13760.0 -177000.0 -4.79 -6.7527 -1.0 3553645 ACon1_000478 CC(C)CC1NC(=O)C23C1C(C)C(=CC3/C=C(\C)/CCC(O)C(O)/C=C/C2=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H23 compound treatment 156080.0 -35700.0 -0.96 163840.0 -27000.0 -0.73 -1.1916 -0.9912 3553179 ACon1_000479 CC(=C)C(=O)O[C@H]1CC(=C)C2C[C@H](O)[C@](O)(CO)C2[C@H]3OC(=O)C(=C)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 H24 compound treatment 164880.0 -26900.0 -0.72 176280.0 -14500.0 -0.39 -0.787 -0.9596 3558419 ACon1_000480 CC(=O)O[C@H]1C(=C)C2C[C@]31CCC4[C@@](C)(CCC[C@@]4(C)C3CC2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I01 compound treatment 196800.0 5010.0 0.13 208760.0 18000.0 0.49 0.4385 0.8697 3557823 ACon1_000481 OC[C@H]1O[C@@H](OC(CCCCc2ccc(O)cc2)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I02 compound treatment 207120.0 15300.0 0.41 274960.0 84200.0 2.28 1.9009 0.8212 3558086 ACon1_000482 CC1(C)OC2(C)CCC1CC2OC3OC(COC(=O)c4cc(O)c(O)c(O)c4)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I03 compound treatment 189480.0 -2310.0 -0.06 178680.0 -12100.0 -0.33 -0.2758 -0.8256 3557594 ACon1_000483 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](C)O[C@@H](OC[C@H]3O[C@@H](Oc4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)cc6)[C@H](O)[C@@H](O)[C@H]3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I04 compound treatment 17800.0 -174000.0 -4.65 17560.0 -173000.0 -4.69 -6.6074 -1.0 3554871 ACon1_000484 COc1cc(cc2OCOc21)[C@H](OC(=O)/C(=C\C)/C)[C@@H](C)OC(=O)[C@](C)(O)[C@H](C)OC(=O)/C(=C\C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I05 mock treatment 185640.0 -6150.0 -0.16 182360.0 -8450.0 -0.23 -0.278 -0.9869 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I06 mock treatment 184880.0 -6910.0 -0.18 200520.0 9710.0 0.26 0.0553 0.172 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I07 compound treatment 84080.0 -108000.0 -2.88 64800.0 -126000.0 -3.41 -4.4494 -0.9965 3554216 ACon1_000485 CCCC(=O)O[C@@H]1C[C@@](C)(OC(=O)C)C2C[C@H](OC(=O)/C(=C/C)/C)C(=C2[C@H]3OC(=O)[C@](C)(O)[C@@]31O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I08 compound treatment 185080.0 -6710.0 -0.18 186880.0 -3930.0 -0.11 -0.2021 -0.9688 3558194 ACon1_000486 CC(=O)O[C@@]1(C)C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I09 compound treatment 183360.0 -8430.0 -0.23 179880.0 -10900.0 -0.3 -0.3686 -0.991 3553540 ACon1_000487 CC(C)C(NC=O)C(=O)OCC(O)C(O)C(O)C(O)COC(=O)C(NC=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I10 compound treatment 186960.0 -4830.0 -0.13 185080.0 -5730.0 -0.16 -0.201 -0.9959 3552799 ACon1_000488 C[C@@H]1O[C@@H](OC(=O)Cc2ccccc2)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I11 compound treatment 170680.0 -21100.0 -0.56 188760.0 -2050.0 -0.06 -0.4384 -0.7728 3553147 ACon1_000489 C[C@H]1CCC[C@H]2C[C@@]3(O)OC(=O)C(=C3C[C@]12C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I12 compound treatment 174800.0 -17000.0 -0.45 227400.0 36600.0 0.99 0.3792 0.3479 3554781 ACon1_000490 COc1c2C(=O)OCc2c(C)c3OC4(C)CC(O)C(C(C)(C)O)C(C)(CCC(=O)O)C4Cc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I13 compound treatment 191040.0 -748.0 -0.02 172800.0 -18000.0 -0.49 -0.3589 -0.7355 3559698 ACon1_000491 C[C@H]1C[C@@]2(O)[C@H]([C@H]1O)[C@@H](O)C(=C)[C@H](O)C[C@H]3[C@@H](/C=C(\C)/C2=O)C3(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I14 compound treatment 178480.0 -13300.0 -0.36 204480.0 13700.0 0.37 0.01 0.0195 3614364 ACon1_000492 CC1OC(=O)C23C(=C)C4(C)OC(=O)C31OC4C5=C(CO)C6(CCC52C)C(O)CC(=O)OC6(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I15 compound treatment 183000.0 -8790.0 -0.24 194160.0 3350.0 0.09 -0.102 -0.405 3553199 ACon1_000493 CC(=CCc1ccc(Oc2c(O)cc(C)cc2CO)c(C(=O)O)c1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I16 compound treatment 174920.0 -16900.0 -0.45 184800.0 -6010.0 -0.16 -0.434 -0.905 3185114 ACon1_000494 CC[C@]1(C=CCN2CC[C@]3([C@H]4N(C)c5cc(OC)ccc53)[C@@H]21)[C@@H](OC(=O)C)[C@]4(O)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I17 compound treatment 192880.0 1090.0 0.03 187920.0 -2890.0 -0.08 -0.0346 -0.4149 3559677 ACon1_000495 C/C(=C\C(=O)O)/CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I18 compound treatment 79560.0 -112000.0 -3.0 85680.0 -105000.0 -2.85 -4.1352 -0.9996 804 ACon1_000496 COc1c(C)c2COC(=O)c2c(O)c1C/C=C(\C)/CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I19 compound treatment 211680.0 19900.0 0.53 185120.0 -5690.0 -0.15 0.2674 0.4827 3557626 ACon1_000497 COc1ccc(CCC(=O)O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I20 compound treatment 14640.0 -177000.0 -4.74 15160.0 -176000.0 -4.76 -6.7131 -1.0 3557415 ACon1_000498 COC(=O)C[C@@H]1C[C@@H](C)C2C([C@@H]1O)C(=O)c3c(O)c4C5CC(O)C(O)(C(C)O5)c4c(O)c3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I21 mock treatment 261960.0 70200.0 1.88 191640.0 833.0 0.02 1.3432 0.7155 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I22 mock treatment 220760.0 29000.0 0.77 173400.0 -17400.0 -0.47 0.2147 0.2368 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I23 compound treatment 230200.0 38400.0 1.03 207880.0 17100.0 0.46 1.0534 0.9349 3557848 ACon1_000499 O[C@@H]1[C@@H](O)[C@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)O[C@@H]([C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 I24 compound treatment 214360.0 22600.0 0.6 202600.0 11800.0 0.32 0.6527 0.9556 3557958 ACon1_000500 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C1CCC3(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J01 compound treatment 55040.0 -137000.0 -3.66 62800.0 -128000.0 -3.47 -5.037 -0.9996 3554282 ACon1_000501 CCCCCCC(O)CCCCCC/C=C/[C@H](OC(=O)C)[C@@H](O)[C@H](O)[C@H](N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J02 compound treatment 208840.0 17100.0 0.46 191200.0 393.0 0.01 0.33 0.7234 831700 ACon1_000502 CC(O)(CC(=O)O)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J03 compound treatment 237120.0 45300.0 1.21 225640.0 34800.0 0.94 1.5242 0.9923 3559146 ACon1_000503 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J04 compound treatment 222280.0 30500.0 0.82 238200.0 47400.0 1.28 1.484 0.9761 3559332 ACon1_000504 CC1C2CCC3(C)C(O)CC=C(C)C3C2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J05 mock treatment 198360.0 6570.0 0.18 193560.0 2750.0 0.07 0.177 0.927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J06 mock treatment 197720.0 5930.0 0.16 227640.0 36800.0 1.0 0.8173 0.8094 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J07 compound treatment 183960.0 -7830.0 -0.21 180960.0 -9850.0 -0.27 -0.3366 -0.9929 3559937 ACon1_000505 C[C@H]1O[C@@H](OC[C@H]2O[C@@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CCC6=C5CC[C@]7(CCC(C)(C)C[C@@H]67)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C3(C)C)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J08 compound treatment 224560.0 32800.0 0.88 245360.0 54600.0 1.48 1.6642 0.969 3558531 ACon1_000506 O[C@H]1[C@@H](C[C@](C[C@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)(OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O)OC(=O)/C=C/c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J09 compound treatment 190800.0 -988.0 -0.03 188600.0 -2210.0 -0.06 -0.0609 -0.9327 2060122 ACon1_000507 CC1(C)Oc2cc3oc(=O)ccc3cc2C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J10 compound treatment 194240.0 2450.0 0.07 184640.0 -6170.0 -0.17 -0.0717 -0.3996 3558561 ACon1_000508 COc1cc2ccc(=O)oc2cc1OCC3OC3(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J11 compound treatment 212320.0 20500.0 0.55 209920.0 19100.0 0.52 0.7542 0.9996 3552721 ACon1_000509 C[C@@H]1CCC2C(C)(C)[C@H](O)CC[C@]2(C)[C@]31Cc4c(O3)c5CNC(=O)c5cc4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J12 compound treatment 212400.0 20600.0 0.55 189400.0 -1410.0 -0.04 0.3629 0.6567 3555910 ACon1_000510 OC[C@H]1O[C@@H](Oc2cccc3cc4COC(=O)c4c(O)c23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J13 compound treatment 108120.0 -83700.0 -2.24 100880.0 -89900.0 -2.43 -3.304 -0.9991 154 ACon1_000511 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J14 compound treatment 192840.0 1050.0 0.03 200720.0 9910.0 0.27 0.2097 0.777 3554559 ACon1_000512 COC(=O)[C@]1(C)OC(=O)[C@@H]2[C@](C)(C(=C)C[C@]3(O)[C@@]4(C)CCC(=O)C(C)(C)C4=C(O)C(=O)[C@@]23C)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J15 compound treatment 210280.0 18500.0 0.49 209280.0 18500.0 0.5 0.7034 1.0 1038770 ACon1_000513 COc1cc(O)c2c(=O)c(OC)c(oc2c1)c3ccc(OC)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J16 compound treatment 197440.0 5650.0 0.15 170120.0 -20700.0 -0.56 -0.2891 -0.4984 3558004 ACon1_000514 OC[C@H]1O[C@@H](O[C@@H]2OC=C([C@H]3CC=C(COC(=O)/C=C/c4ccccc4)[C@H]32)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J17 compound treatment 146240.0 -45500.0 -1.22 130440.0 -60400.0 -1.63 -2.0171 -0.9895 3552617 ACon1_000515 C[C@@H]1[C@@H](C[C@]23COC(=O)C3=CCC[C@@H]2[C@@]1(C)CC(OC(=O)C)c4ccoc4)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J18 compound treatment 156320.0 -35500.0 -0.95 133920.0 -56900.0 -1.54 -1.7599 -0.9729 1062454 ACon1_000516 COc1c(O)cc2oc(cc(=O)c2c1O)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J19 compound treatment 194080.0 2290.0 0.06 198440.0 7630.0 0.21 0.1895 0.879 3559776 ACon1_000517 CCOC(=O)C1C(=O)C(=O)Nc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J20 compound treatment 42640.0 -149000.0 -3.99 17240.0 -174000.0 -4.7 -6.1437 -0.9967 3554280 ACon1_000518 CCCCCCC(C)C/C(=C\C(CO)\C=C(/C)\C=C\C(O)C(C)(C)c1cc(O)c([C@H]2O[C@@H](CO)C[C@@H](O)[C@@H]2O)c(=O)o1)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J21 mock treatment 193200.0 1410.0 0.04 183400.0 -7410.0 -0.2 -0.1151 -0.564 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J22 mock treatment 215040.0 23300.0 0.62 225000.0 34200.0 0.93 1.0943 0.9813 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J23 compound treatment 192000.0 212.0 0.01 196840.0 6030.0 0.16 0.1195 0.7312 3554751 ACon1_000519 COC1=CC(=O)O[C@@H](CCc2ccccc2)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 J24 compound treatment 216160.0 24400.0 0.65 225880.0 35100.0 0.95 1.1324 0.9832 3558337 ACon1_000520 O[C@@H]1C=C(C[C@@H](O[C@@H]2O[C@H](COC(=O)/C=C/c3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K01 compound treatment 177640.0 -14100.0 -0.38 170120.0 -20700.0 -0.56 -0.6636 -0.9818 3557834 ACon1_000521 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]4OC[C@](O)(CO)[C@H]4O)[C@H]2OC(=O)/C=C/c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K02 compound treatment 226240.0 34500.0 0.92 241040.0 50200.0 1.36 1.6132 0.982 3558087 ACon1_000522 OCC1OC(Oc2cc(O)c(C(=O)O)c(/C=C/c3ccccc3)c2)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K03 compound treatment 210480.0 18700.0 0.5 203640.0 12800.0 0.35 0.5992 0.9842 3558017 ACon1_000523 COc1cc(O)c2c(=O)c(OC3OC(CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H]4O)C(O)C(O)C3O)c(oc2c1)c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K04 compound treatment 14720.0 -177000.0 -4.74 15520.0 -175000.0 -4.75 -6.7047 -1.0 3554289 ACon1_000524 CCCCCCCC(=O)O[C@H]1[C@H](OC(=O)/C(=C/C)/C)C(=C2[C@H]3OC(=O)[C@](C)(O)[C@]3(O)[C@@H](C[C@@](C)(OC(=O)C)[C@H]12)OC(=O)C(C)CC)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K05 compound treatment 181200.0 -10600.0 -0.28 205560.0 14800.0 0.4 0.0821 0.1678 3558061 ACon1_000525 CC1CC(O)C2C(OC(=O)C2=C)C3=C(C)C(=O)CC13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K06 compound treatment 223680.0 31900.0 0.85 221800.0 31000.0 0.84 1.1965 1.0 3555625 ACon1_000526 O[C@H]1[C@H](O)[C@@H](COC(=O)c2ccccc2)O[C@@H](Oc3ccc(O)cc3COC(=O)C4(O)C=CCCC4=O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K07 mock treatment 188560.0 -3230.0 -0.09 195720.0 4910.0 0.13 0.033 0.208 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K08 mock treatment 240240.0 48500.0 1.3 196840.0 6030.0 0.16 1.0319 0.79 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K09 compound treatment 207320.0 15500.0 0.42 236480.0 45700.0 1.24 1.1681 0.8955 3559841 ACon1_000527 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@H](COC(=O)C)[C@@H](O)[C@@H](O)[C@H]5O)c(O)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K10 compound treatment 208400.0 16600.0 0.44 196360.0 5550.0 0.15 0.4205 0.8964 3554769 ACon1_000528 COc1c(O)cc2C(O)C(C)OC(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K11 compound treatment 189000.0 -2790.0 -0.07 215560.0 24800.0 0.67 0.4211 0.6246 3557888 ACon1_000529 OC[C@H]1O[C@@H](OC(C#N)c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K12 compound treatment 198120.0 6330.0 0.17 198120.0 7310.0 0.2 0.2598 0.997 3614365 ACon1_000530 CC1(CO)CCCC2(C)C1C(=O)CC3=C2COC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K13 compound treatment 201960.0 10200.0 0.27 190560.0 -248.0 -0.01 0.1877 0.6895 3559595 ACon1_000531 C/C/1=C\CC[C@@]2(C)O[C@@H]2C[C@H]3[C@H](C1)OC(=O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K14 compound treatment 212720.0 20900.0 0.56 214680.0 23900.0 0.65 0.8529 0.9974 3557305 ACon1_000532 COc1cc(O)cc(C(=O)O)c1Oc2cc(C)cc(O)c2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K15 mock treatment 183640.0 -8150.0 -0.22 227280.0 36500.0 0.99 0.5441 0.5381 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K16 mock treatment 199560.0 7770.0 0.21 189720.0 -1090.0 -0.03 0.1262 0.601 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K17 compound treatment 183000.0 -8790.0 -0.24 204480.0 13700.0 0.37 0.0955 0.2178 3614366 ACon1_000533 CC(C)CC1NC(=O)C(C)NC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K18 compound treatment 194000.0 2210.0 0.06 206400.0 15600.0 0.42 0.3403 0.7984 3559135 ACon1_000534 O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K19 compound treatment 207160.0 15400.0 0.41 205480.0 14700.0 0.4 0.5716 0.9999 3557598 ACon1_000535 COc1c(O)cc2oc(c(OC)c(=O)c2c1O)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K20 compound treatment 194440.0 2650.0 0.07 205040.0 14200.0 0.39 0.3226 0.8235 3558949 ACon1_000536 C[C@@H]1O[C@@H](O[C@@H]2CO[C@@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@]3(C)CO)[C@H](O)[C@H]2O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K21 compound treatment 202800.0 11000.0 0.29 212200.0 21400.0 0.58 0.6178 0.9508 3552947 ACon1_000537 C[C@H]1[C@@H](O)C[C@H]2[C@@H]1[C@H](OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K22 compound treatment 207840.0 16100.0 0.43 224600.0 33800.0 0.91 0.9505 0.9405 1092498 ACon1_000538 OCC(O)c1nc(CO)cc2c3ccccc3[nH]c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K23 mock treatment 211360.0 19600.0 0.52 209760.0 19000.0 0.51 0.733 0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 K24 mock treatment 201640.0 9850.0 0.26 201720.0 10900.0 0.3 0.3952 0.9984 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L01 compound treatment 194000.0 2210.0 0.06 194440.0 3630.0 0.1 0.1114 0.9704 3554760 ACon1_000539 COc1c(CO)c(O)cc2C(O)CCC(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L02 compound treatment 237600.0 45800.0 1.23 220520.0 29700.0 0.8 1.4353 0.9792 3559718 ACon1_000540 C[C@H]1C[C@H](O)C[C@H]2[C@H](OC(=O)C=C(C)C)[C@H](O)[C@H](C[C@]12C)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L03 compound treatment 28800.0 -163000.0 -4.36 21040.0 -170000.0 -4.6 -6.3327 -0.9997 3558002 ACon1_000541 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)/C=C/c7ccccc7)[C@H]1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L04 compound treatment 208920.0 17100.0 0.46 207080.0 16300.0 0.44 0.6355 0.9998 3559482 ACon1_000542 C/C=C(\C)/C(=O)O[C@@H]1C\C(=C\CC\C(=C\[C@H]2OC(=O)C(=C)C21)\C)\C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L05 compound treatment 185640.0 -6150.0 -0.16 197080.0 6270.0 0.17 0.0038 0.016 592 ACon1_000543 Oc1ccc(cc1)c2coc3cc(O)ccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L06 compound treatment 230200.0 38400.0 1.03 235880.0 45100.0 1.22 1.5894 0.9963 3614367 ACon1_000544 C[C@H]1[C@H](O)CCC2=CC(=O)[C@H](C[C@]12C)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L07 mock treatment 191960.0 172.0 0.0 187320.0 -3490.0 -0.09 -0.0635 -0.6718 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L08 mock treatment 194760.0 2970.0 0.08 195160.0 4350.0 0.12 0.1395 0.9816 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L09 compound treatment 202360.0 10600.0 0.28 183880.0 -6930.0 -0.19 0.0673 0.1985 1024930 ACon1_000545 COc1c2C=CC(C)(C)Oc2cc3oc(=O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L10 compound treatment 190440.0 -1350.0 -0.04 201160.0 10400.0 0.28 0.1727 0.6111 3558539 ACon1_000546 OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC[C@@]3(O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L11 compound treatment 143200.0 -48600.0 -1.3 182160.0 -8650.0 -0.23 -1.0845 -0.8213 3557749 ACon1_000547 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)OCC(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L12 compound treatment 197280.0 5490.0 0.15 205360.0 14600.0 0.39 0.3825 0.9096 3555408 ACon1_000548 CSC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]1[C@H]23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L13 compound treatment 220240.0 28500.0 0.76 203960.0 13200.0 0.36 0.7899 0.9401 1010501 ACon1_000549 Cn1c(=O)n(C)c2c(=O)n(C)c(=O)n(C)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L14 compound treatment 204920.0 13100.0 0.35 226920.0 36100.0 0.98 0.9397 0.9046 3558008 ACon1_000550 COc1cc(/C=C/C(=O)O[C@@H]2C[C@](O)(C[C@@H](O)[C@@H]2O)C(=O)O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L15 mock treatment 197000.0 5210.0 0.14 170200.0 -20600.0 -0.56 -0.2959 -0.5146 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L16 mock treatment 183480.0 -8310.0 -0.22 178480.0 -12300.0 -0.33 -0.3931 -0.9805 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L17 compound treatment 175840.0 -15900.0 -0.43 180800.0 -10000.0 -0.27 -0.4932 -0.976 2060138 ACon1_000551 C[C@]1([C@H]2[C@H](C(=O)O)[C@]3(CC(=C)[C@@]4(O)C3)[C@@H](CC4)[C@]52OC1=O)[C@@H](O)C=C5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L18 compound treatment 196560.0 4770.0 0.13 198760.0 7950.0 0.22 0.2425 0.9689 3558019 ACon1_000552 CC1C2CC3C(CCC(=O)C)C3(C)CC2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L19 compound treatment 56360.0 -135000.0 -3.62 46280.0 -145000.0 -3.91 -5.3282 -0.9993 3559721 ACon1_000553 C/C(=C\CO)/C(=O)O[C@@H]1C\C(=C\CC[C@@]2(C)OC2[C@H]3OC(=O)C(=C)C31)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L20 compound treatment 213320.0 21500.0 0.58 245840.0 55000.0 1.49 1.4608 0.9145 3558114 ACon1_000554 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(COC(=O)/C=C/c5ccccc5)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L21 compound treatment 119320.0 -72500.0 -1.94 103080.0 -87700.0 -2.38 -3.0501 -0.9949 3553337 ACon1_000555 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@]2(C)[C@@H](CC3[C@H](OC(=O)C3=C)[C@H]2C1=C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L22 compound treatment 194480.0 2690.0 0.07 201840.0 11000.0 0.3 0.2621 0.8531 3558119 ACon1_000556 COc1ccc(/C=C/C(=O)OC2CC(C)(O)C3C(OC4OC(CO)C(O)C(O)C4O)OC=CC23O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L23 mock treatment 187480.0 -4310.0 -0.12 198520.0 7710.0 0.21 0.0662 0.2774 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 L24 mock treatment 207280.0 15500.0 0.41 198960.0 8150.0 0.22 0.4491 0.9565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M01 compound treatment 204720.0 12900.0 0.35 187840.0 -2970.0 -0.08 0.1878 0.5288 3557875 ACon1_000557 CC(CCc1ccc(O)cc1)O[C@@H]2O[C@H](CO[C@H]3OC[C@](O)(CO)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M02 compound treatment 184080.0 -7710.0 -0.21 215160.0 24400.0 0.66 0.3204 0.4638 3558144 ACon1_000558 Cc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M03 compound treatment 239400.0 47600.0 1.27 220280.0 29500.0 0.8 1.4647 0.9746 3557783 ACon1_000559 O[C@H]1CO[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M04 compound treatment 214040.0 22300.0 0.6 212440.0 21600.0 0.59 0.835 1.0 353 ACon1_000560 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M05 compound treatment 188680.0 -3110.0 -0.08 208440.0 17600.0 0.48 0.2788 0.5753 3555963 ACon1_000561 OCC1OC(OC(=O)c2c(O)cc(O)cc2/C=C/c3ccccc3)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M06 compound treatment 84840.0 -107000.0 -2.86 90520.0 -100000.0 -2.72 -3.9427 -0.9997 3557538 ACon1_000562 CC1CC2OC(=O)C(=C)C2CC3OC31/C=C/C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M07 compound treatment 15360.0 -176000.0 -4.72 15280.0 -176000.0 -4.75 -6.6972 -1.0 3558167 ACon1_000563 CCCCCC(=O)OC1C(OC(=O)/C(=C/C)/C)C(=C2C3OC(=O)C(C)(O)C3(O)C(CC(C)(OC(=O)C)C12)OC(=O)CCC)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M08 compound treatment 177680.0 -14100.0 -0.38 214360.0 23600.0 0.64 0.184 0.2484 3558079 ACon1_000564 CC(=O)O[C@@]1(C)C[C@@H](O)[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M09 mock treatment 172320.0 -19500.0 -0.52 189360.0 -1450.0 -0.04 -0.3959 -0.7582 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M10 mock treatment 188720.0 -3070.0 -0.08 195200.0 4390.0 0.12 0.0261 0.1804 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M11 compound treatment 221400.0 29600.0 0.79 204440.0 13600.0 0.37 0.8211 0.9396 3558160 ACon1_000565 COc1cc(O)c2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M12 compound treatment 210240.0 18500.0 0.49 195320.0 4510.0 0.12 0.4354 0.8563 3614369 ACon1_000566 COc1ccc(C(=O)Oc2ccc(C)c3CC(C)OC(=O)c23)c4CC(C)OC(=O)c14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M13 mock treatment 208640.0 16900.0 0.45 198600.0 7790.0 0.21 0.4679 0.9402 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M14 mock treatment 188200.0 -3590.0 -0.1 182680.0 -8130.0 -0.22 -0.2234 -0.9308 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M15 compound treatment 166760.0 -25000.0 -0.67 182840.0 -7970.0 -0.22 -0.6259 -0.8899 3554270 ACon1_000567 CCCCCC(O)CC(O)CC(=O)OC(CCCCC)CC(O)CC(=O)OCC(O)C(O)C(O)C(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M16 compound treatment 14800.0 -177000.0 -4.73 14520.0 -176000.0 -4.77 -6.7223 -1.0 3559697 ACon1_000568 CC1(C)[C@H](O)CC[C@@]2(C)[C@H](COc3ccc4ccc(=O)oc4c3)C(=C)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M17 compound treatment 183440.0 -8350.0 -0.22 217480.0 26700.0 0.72 0.3527 0.4666 3614370 ACon1_000569 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@@H]3[C@@H](O)[C@H](O)[C@H](O[C@H]3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)C[C@@H](O)[C@]8(C)CC[C@]76C)[C@@]4(C)CO)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M18 compound treatment 181200.0 -10600.0 -0.28 196800.0 5990.0 0.16 -0.0855 -0.2621 3554688 ACon1_000570 COC(=O)C1=CO[C@@H](OC2OC(CO)C(O)C(O)C2O)[C@H](C=C)[C@@H]1CCOC(=O)c3cc(O)c(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M19 compound treatment 212560.0 20800.0 0.56 208960.0 18200.0 0.49 0.7404 0.9981 3553705 ACon1_000571 CC(CCC1(O)OC(=O)C=C1C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M20 compound treatment 191600.0 -188.0 -0.01 203680.0 12900.0 0.35 0.2429 0.6968 3559384 ACon1_000572 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@H](C[C@@H]31)OC(=O)C4=CO[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H]6[C@@H](C)[C@@H](O)C[C@@H]64 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M21 compound treatment 183360.0 -8430.0 -0.23 212960.0 22200.0 0.6 0.2647 0.4131 3557814 ACon1_000573 COc1cc(cc(OC)c1O)C2C(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(CO)Cc4cc(OC)c(O)c(OC)c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M22 compound treatment 142520.0 -49300.0 -1.32 122840.0 -68000.0 -1.84 -2.233 -0.9866 1023017 ACon1_000574 COc1cc2oc(=O)ccc2cc1CC=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M23 compound treatment 191840.0 52.1 0.0 210000.0 19200.0 0.52 0.3684 0.709 3558029 ACon1_000575 COc1ccc(CCO[C@@H]2O[C@H](CO[C@@H]3OC[C@H](O)[C@H](O)[C@H]3O)[C@@H](OC(=O)/C=C/c4ccc(O)c(OC)c4)[C@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H]2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 M24 compound treatment 221200.0 29400.0 0.79 200360.0 9550.0 0.26 0.7392 0.8926 3559875 ACon1_000576 COc1ccc(cc1)c2oc3cc(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)cc(O)c3c(=O)c2O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N01 compound treatment 209200.0 17400.0 0.47 215720.0 24900.0 0.67 0.8062 0.9837 3558056 ACon1_000577 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCc3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N02 compound treatment 248480.0 56700.0 1.52 198240.0 7430.0 0.2 1.2146 0.794 2118288 ACon1_000578 CCCC#C/C=C/1\OC(=O)C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N03 compound treatment 200520.0 8730.0 0.23 197160.0 6350.0 0.17 0.2868 0.9887 3558083 ACon1_000579 CC(=O)OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N04 compound treatment 26720.0 -165000.0 -4.42 29680.0 -161000.0 -4.36 -6.2066 -1.0 3553187 ACon1_000580 CC(=CCC/C(=C/COc1cc(=O)oc2cccc(C)c12)/COC(=O)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N05 compound treatment 184280.0 -7510.0 -0.2 203400.0 12600.0 0.34 0.0991 0.2503 3173763 ACon1_000581 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N06 compound treatment 197600.0 5810.0 0.16 189400.0 -1410.0 -0.04 0.083 0.5184 1733214 ACon1_000582 Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N07 compound treatment 183440.0 -8350.0 -0.22 187520.0 -3290.0 -0.09 -0.2208 -0.9187 1043213 ACon1_000583 COC(=O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N08 compound treatment 184440.0 -7350.0 -0.2 178520.0 -12300.0 -0.33 -0.3742 -0.9685 3558609 ACon1_000584 COc1cc(ccc1O)[C@H]2OC[C@](O)(Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)[C@@H]2CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N09 mock treatment 177960.0 -13800.0 -0.37 188560.0 -2250.0 -0.06 -0.3046 -0.8125 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N10 mock treatment 196400.0 4610.0 0.12 177120.0 -13700.0 -0.37 -0.1748 -0.4475 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N11 compound treatment 191800.0 12.1 0.0 201600.0 10800.0 0.29 0.2068 0.7079 3553255 ACon1_000585 CC(=O)CCCC1Cc2cccc(O)c2C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N12 compound treatment 225880.0 34100.0 0.91 224120.0 33300.0 0.9 1.2825 1.0 3553375 ACon1_000586 CC(=O)OC[C@@]12CCC(=CC2O[C@@H]3[C@H](O)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@]1(C)C53CO5)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N13 mock treatment 201120.0 9330.0 0.25 202080.0 11300.0 0.31 0.3923 0.995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N14 mock treatment 195240.0 3450.0 0.09 195760.0 4950.0 0.13 0.1601 0.9834 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N15 compound treatment 17880.0 -174000.0 -4.65 14520.0 -176000.0 -4.77 -6.664 -0.9999 1303116 ACon1_000587 Oc1cc(O)c(C(=O)CCc2ccccc2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N16 compound treatment 200400.0 8610.0 0.23 180400.0 -10400.0 -0.28 -0.0363 -0.0999 3557944 ACon1_000588 C/C(=C\C(=O)O)/CCC1=C(C)CCC2C(C)(C)CCC[C@@]21C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N17 compound treatment 179200.0 -12600.0 -0.34 182440.0 -8370.0 -0.23 -0.3983 -0.9814 3559690 ACon1_000589 COC(=O)C1[C@@H]2Cc3c([nH]c4ccccc34)C(=O)C[C@@H]1/C(=C\C)/CN2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N18 compound treatment 185720.0 -6070.0 -0.16 185080.0 -5730.0 -0.16 -0.2244 -0.9997 3558020 ACon1_000590 OC[C@H]1OC([C@H](O)[C@@H](O)[C@H]1O)c2c(O)cc(O)c3c(=O)cc(oc23)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N19 compound treatment 186960.0 -4830.0 -0.13 167840.0 -23000.0 -0.62 -0.531 -0.8361 3559729 ACon1_000591 CC1=CC2(CC1CC=C23)CCC4[C@](C)(CO)[C@H](O)CC[C@]43C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N20 compound treatment 211120.0 19300.0 0.52 202560.0 11800.0 0.32 0.5906 0.9728 3558252 ACon1_000592 COc1cc2occc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N21 compound treatment 19320.0 -172000.0 -4.61 16600.0 -174000.0 -4.72 -6.597 -0.9999 3553911 ACon1_000593 CC1=C2[C@@H]3OC(=O)C(=C)[C@@H]3CC(=O)[C@@]2(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N22 compound treatment 190600.0 -1190.0 -0.03 185720.0 -5090.0 -0.14 -0.1199 -0.848 3558104 ACon1_000594 CC1CC(=O)[C@@]2(O)[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)OCCc4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N23 compound treatment 198600.0 6810.0 0.18 211920.0 21100.0 0.57 0.533 0.8885 3554077 ACon1_000595 Cc1cccc2oc(=O)c3c(O[C@@]4(C[C@]3(C)C=C)OC[C@@]5(C)O[C@H]54)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 N24 compound treatment 10240.0 -182000.0 -4.86 9960.0 -181000.0 -4.9 -6.8958 -1.0 3558467 ACon1_000596 Oc1cc(O)cc(CCCCCCC/C=C\C/C=C\CC=C)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O01 compound treatment 213680.0 21900.0 0.59 226720.0 35900.0 0.97 1.1016 0.9706 3557850 ACon1_000597 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O02 compound treatment 171120.0 -20700.0 -0.55 214520.0 23700.0 0.64 0.063 0.0744 3558145 ACon1_000598 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@@H]2OC(=O)[C@@]34CCC(C)(C)CC4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@](C)(C7CC[C@@]6(C)[C@]5(C)CC3)C(=O)O)[C@H](O)[C@H](O)[C@H]1O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O03 compound treatment 191120.0 -668.0 -0.02 184200.0 -6610.0 -0.18 -0.1391 -0.7739 3554994 ACon1_000599 COc1cc(O)cc(c2cc(O)c(O)cc2C)c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O04 compound treatment 21120.0 -171000.0 -4.57 40240.0 -151000.0 -4.08 -6.1104 -0.9984 3558210 ACon1_000600 Oc1ccc(/C=C/C(=O)NCCCCN(CCCN(CCCNC(=O)\C=C\c2ccc(O)cc2)C(=O)\C=C\c3ccc(O)cc3)C(=O)\C=C\c4ccc(O)cc4)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O05 compound treatment 182840.0 -8950.0 -0.24 194000.0 3190.0 0.09 -0.1081 -0.4249 3558099 ACon1_000601 COc1ccc(cc1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O[C@@H]5O[C@H](CO)C(O)[C@H](O)[C@H]5O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O06 compound treatment 74200.0 -118000.0 -3.15 98680.0 -92100.0 -2.49 -3.9877 -0.9934 3557819 ACon1_000602 COC(=O)/C=C(\C)/CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O07 compound treatment 157160.0 -34600.0 -0.93 168000.0 -22800.0 -0.62 -1.0916 -0.9806 3558175 ACon1_000603 CC1CC2OC(=O)C(=C)C2CC=C1CCC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O08 compound treatment 178280.0 -13500.0 -0.36 193480.0 2670.0 0.07 -0.2043 -0.5545 3557525 ACon1_000604 CC1OC(OC2C(O)C(OCCc3ccc(O)c(O)c3)OC(CO)C2OC(=O)/C=C/c4ccc(O)c(O)c4)C(OC5OCC(O)C(O)C5O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O09 compound treatment 148680.0 -43100.0 -1.15 168200.0 -22600.0 -0.61 -1.2481 -0.9561 3614377 ACon1_000605 C[C@H]1[C@H](O)CCC2=CC(=O)[C@@]3(O[C@@H]3[C@]12C)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O10 compound treatment 16960.0 -175000.0 -4.68 26080.0 -165000.0 -4.46 -6.4601 -0.9997 3558377 ACon1_000606 CC(=CCc1c(O)cc2occ(c3ccc(O)cc3O)c(=O)c2c1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O11 mock treatment 190400.0 -1390.0 -0.04 203040.0 12200.0 0.33 0.2079 0.6239 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O12 mock treatment 189280.0 -2510.0 -0.07 208560.0 17800.0 0.48 0.2924 0.6026 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O13 compound treatment 213560.0 21800.0 0.58 180760.0 -10000.0 -0.27 0.2195 0.3414 3558336 ACon1_000607 COc1cc(cc(OC)c1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc5OCOc5c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O14 compound treatment 191400.0 -388.0 -0.01 188240.0 -2570.0 -0.07 -0.0565 -0.8038 3559606 ACon1_000608 COc1cc(CCc2ccc3OCOc3c2)oc(=O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O15 compound treatment 173400.0 -18400.0 -0.49 192560.0 1750.0 0.05 -0.3142 -0.6359 3553200 ACon1_000609 CC(=CCCC(C)(O)C(O)CC(OC(=O)C)/C(=C/COCC(O)C(O)C(O)C(O)CO)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O16 compound treatment 13200.0 -179000.0 -4.78 12720.0 -178000.0 -4.82 -6.787 -1.0 3074726 ACon1_000610 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5CC[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O17 compound treatment 188160.0 -3630.0 -0.1 189320.0 -1490.0 -0.04 -0.0971 -0.9241 3557679 ACon1_000611 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O18 compound treatment 200240.0 8450.0 0.23 198960.0 8150.0 0.22 0.3159 0.9999 3559274 ACon1_000612 COc1cc(OC)c(O[C@@H]2O[C@H](COC(=O)c3cc(O)c(O)c(O)c3)[C@@H](O)[C@H](O)[C@H]2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O19 compound treatment 15640.0 -176000.0 -4.71 20800.0 -170000.0 -4.6 -6.5862 -0.9999 3557735 ACon1_000613 COC1CC(O[C@H]2CC[C@@]3(C)C(CCC4C3CC[C@]5(C)C(CCC45O)C6=CC(=O)OC6)C2)OC(C)C1OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O20 compound treatment 189200.0 -2590.0 -0.07 221960.0 31200.0 0.84 0.5474 0.6469 3558277 ACon1_000614 C[C@@H]1O[C@@H](O[C@H]2[C@H](C)O[C@@H](Oc3c(oc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc(O)c4c3=O)c6ccc(O)cc6)[C@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O21 compound treatment 149520.0 -42300.0 -1.13 158520.0 -32300.0 -0.87 -1.4176 -0.9919 3557827 ACon1_000615 OC(CCCCc1ccc(O)cc1)CCc2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O22 compound treatment 205840.0 14100.0 0.38 222120.0 31300.0 0.85 0.8652 0.933 3557897 ACon1_000616 C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O23 compound treatment 196880.0 5090.0 0.14 197360.0 6550.0 0.18 0.2217 0.9915 3555034 ACon1_000617 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)O[C@@H](C)[C@H](O)[C@H]2OC(=O)C)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 O24 compound treatment 236800.0 45000.0 1.2 208120.0 17300.0 0.47 1.1828 0.9154 3559877 ACon1_000618 OC[C@H]1O[C@@H](Oc2cc(O)c(C(=O)CCc3ccc(O)cc3)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P01 compound treatment 195680.0 3890.0 0.1 202600.0 11800.0 0.32 0.2994 0.8915 3559267 ACon1_000619 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CCC4[C@@]5(C)[C@H]([C@H](O)[C@](C)(CO)C5CC[C@]43C)C(=O)O)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P02 compound treatment 6520.0 -185000.0 -4.96 8680.0 -182000.0 -4.93 -6.9907 -1.0 3559411 ACon1_000620 CC(C)[C@@H]1CC[C@@]2(C)CCC[C@@](C)(O)[C@@H]2[C@H]1OC(=O)/C=C/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P03 compound treatment 22640.0 -169000.0 -4.52 92200.0 -98600.0 -2.67 -5.087 -0.9683 3557780 ACon1_000621 C/C(=C\CO)/CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P04 compound treatment 193200.0 1410.0 0.04 200320.0 9510.0 0.26 0.2088 0.8022 1506 ACon1_000622 OCc1cc(=O)c(O)co1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P05 compound treatment 230560.0 38800.0 1.04 231080.0 40300.0 1.09 1.5043 0.9997 3557935 ACon1_000623 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P06 compound treatment 66400.0 -125000.0 -3.35 123160.0 -67600.0 -1.83 -3.6666 -0.9595 3554108 ACon1_000624 CCC(C)/C=C(\C)/C=C/C1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P07 compound treatment 179440.0 -12300.0 -0.33 203400.0 12600.0 0.34 0.0075 0.0158 1043213 ACon1_000625 COC(=O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P08 compound treatment 193680.0 1890.0 0.05 194600.0 3790.0 0.1 0.1084 0.9469 3557255 ACon1_000626 OC(=O)C(=C)Oc1cccc(c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P09 compound treatment 183200.0 -8590.0 -0.23 201760.0 11000.0 0.3 0.0472 0.1259 3559264 ACon1_000627 COc1cc2oc(cc(=O)c2c(O)c1OC)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P10 compound treatment 204400.0 12600.0 0.34 204080.0 13300.0 0.36 0.4926 0.9995 3553970 ACon1_000628 Cc1cc(=O)c2c(O)c3CC(Oc3cc2o1)C(C)(C)OC4OC(CO)C(O)C(O)C4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P11 mock treatment 186640.0 -5150.0 -0.14 196560.0 5750.0 0.16 0.0128 0.0613 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P12 mock treatment 191720.0 -67.9 0.0 185640.0 -5170.0 -0.14 -0.1002 -0.7162 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P13 compound treatment 117320.0 -74500.0 -1.99 131440.0 -59400.0 -1.61 -2.545 -0.9943 3553930 ACon1_000629 CC1=CC(=O)C[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3CC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P14 compound treatment 190280.0 -1510.0 -0.04 197000.0 6190.0 0.17 0.09 0.5221 3557957 ACon1_000630 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C(C)C(O)CC31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P15 compound treatment 197280.0 5490.0 0.15 197920.0 7110.0 0.19 0.24 0.9911 3559851 ACon1_000631 COc1cc(O)c(C(=O)/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P16 compound treatment 9840.0 -182000.0 -4.87 9240.0 -182000.0 -4.92 -6.9172 -1.0 3554298 ACon1_000632 CCCCCCCCCC(O)CC(O)CC(O)CC1CC=CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P17 compound treatment 175960.0 -15800.0 -0.42 165920.0 -24900.0 -0.67 -0.7758 -0.9749 3559696 ACon1_000633 COc1cc2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc5OCOc5c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P18 compound treatment 189600.0 -2190.0 -0.06 204120.0 13300.0 0.36 0.2135 0.5846 3558198 ACon1_000634 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccc(O)c(O)c6)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P19 compound treatment 148600.0 -43200.0 -1.16 198880.0 8070.0 0.22 -0.6623 -0.5633 3559409 ACon1_000635 CC(C)[C@@H]1CC[C@@]2(C)[C@H](O)CC[C@@](C)(O)[C@@H]2[C@@H]1OC(=O)/C=C/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P20 compound treatment 200560.0 8770.0 0.23 193720.0 2910.0 0.08 0.2217 0.8955 3558052 ACon1_000636 COc1cc2ccc(=O)oc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P21 compound treatment 13000.0 -179000.0 -4.78 60360.0 -130000.0 -3.53 -5.8788 -0.9889 1001932 ACon1_000637 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P22 compound treatment 188840.0 -2950.0 -0.08 160680.0 -30100.0 -0.82 -0.6325 -0.7719 3559888 ACon1_000638 Oc1ccc(c(O)c1)c2coc3cc(O)cc(O)c3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P23 compound treatment 206040.0 14300.0 0.38 215040.0 24200.0 0.66 0.7335 0.9666 3559630 ACon1_000639 CC(C)C(=O)OCC(=C)C1Oc2cc(ccc2C1OC(=O)C(C)C)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2291 P24 compound treatment 213760.0 22000.0 0.59 223440.0 32600.0 0.88 1.0403 0.9804 3558347 ACon1_000640 C[C@]1(CCC[C@]2(C)C1CC[C@]3(CC4CC[C@]32O)CC4=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A01 compound treatment 243600.0 65100.0 1.74 224200.0 27200.0 0.74 1.7519 0.9266 3558339 ACon1_000641 COC(=O)C1=C[C@@H](O)[C@@H](O)[C@@H](C1)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)/C=C/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A02 compound treatment 215200.0 36700.0 0.98 245480.0 48500.0 1.31 1.6221 0.9898 3558365 ACon1_000642 CC(=CCC/C(=C/C(C/C(=C/C(CC(C)(O)C=C)OC(=O)C)/C)OC(=O)C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A03 compound treatment 141320.0 -37200.0 -0.99 135000.0 -62000.0 -1.68 -1.8903 -0.9688 3558431 ACon1_000643 CC(=CCC(O)/C(=C/CCC(C)(OC1OC(CO)C(O)C(O)C1O)C=C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A04 compound treatment 153120.0 -25400.0 -0.68 165280.0 -31700.0 -0.86 -1.0874 -0.9932 3559889 ACon1_000644 CCC(=O)OCC1=CCCC2C(C)(CCC(C)CC(=O)O)C(C)CCC21C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A05 compound treatment 224240.0 45700.0 1.22 210200.0 13200.0 0.36 1.1177 0.8769 3558559 ACon1_000645 COc1cc2ccc(=O)oc2cc1OCC(O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A06 compound treatment 206760.0 28300.0 0.76 195120.0 -1890.0 -0.05 0.4984 0.6577 3558221 ACon1_000646 C[C@@H]1CC[C@]2(C)[C@H](CC[C@@H](O)[C@]2(C)O)[C@@]1(C)CC(=O)c3ccoc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A07 compound treatment 195200.0 16700.0 0.45 206480.0 9470.0 0.26 0.4972 0.9652 3614399 ACon1_000647 COc1cc(O)cc2cc3C[C@](C)(O)CC(=O)c3c(O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A08 compound treatment 148680.0 -29800.0 -0.8 128560.0 -68500.0 -1.85 -1.8743 -0.929 3559065 ACon1_000648 COc1cc2OC(C)(C)C=Cc2c3oc(cc(=O)c13)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A09 compound treatment 160080.0 -18400.0 -0.49 175200.0 -21800.0 -0.59 -0.7659 -0.9959 3557259 ACon1_000649 COc1c(C)c(oc(=O)c1C)[C@@]2(C)O[C@H]2/C(=C\C(=C\[C@@]3(C)O[C@@H](C)[C@]4(C)OC43)\C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A10 compound treatment 200640.0 22100.0 0.59 171800.0 -25200.0 -0.68 -0.0638 -0.0706 3559150 ACon1_000650 COc1ccc(cc1O)c2coc3cc(O)ccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A11 compound treatment 212920.0 34400.0 0.92 189600.0 -7410.0 -0.2 0.5092 0.5403 3553959 ACon1_000651 CC1C2C(CC(C)(O)C3CC4OC4(C)C3(O)C2=O)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A12 compound treatment 201920.0 23400.0 0.63 187200.0 -9810.0 -0.27 0.2552 0.375 3614402 ACon1_000652 COc1ccc(cc1)C2Oc3cc(OC)ccc3CC2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A13 mock treatment 205760.0 27300.0 0.73 201960.0 4950.0 0.13 0.6104 0.8232 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A14 mock treatment 218840.0 40300.0 1.08 191200.0 -5810.0 -0.16 0.6518 0.5977 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A15 compound treatment 215320.0 36800.0 0.98 194640.0 -2370.0 -0.06 0.6511 0.6596 3557496 ACon1_000653 CC(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)/C=C/[C@@]2(O)C(=CC(=O)CC2(C)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A16 compound treatment 249360.0 70900.0 1.9 233080.0 36100.0 0.98 2.0308 0.9524 3554158 ACon1_000654 CCC(C)C1NC(=O)c2c1n(C)c3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A17 compound treatment 197840.0 19300.0 0.52 182320.0 -14700.0 -0.4 0.0846 0.1297 3558190 ACon1_000655 C[C@H]1[C@@]2(O)[C@H](CC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@@]32C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)O[C@@]71CCC(C)CO7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A18 compound treatment 189400.0 10900.0 0.29 197600.0 588.0 0.02 0.2175 0.7446 3554284 ACon1_000656 CCCCCCC1OC(=O)CCCC(O)/C=C\C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A19 compound treatment 222280.0 43800.0 1.17 194560.0 -2450.0 -0.07 0.7812 0.666 3551961 ACon1_000657 C/C(=C\C(=O)OC1C(=CC=C(C=O)C1(C)C)C)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A20 compound treatment 188680.0 10200.0 0.27 190880.0 -6130.0 -0.17 0.0752 0.2358 3558454 ACon1_000658 CC1CCC23CCC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C13C(=CC2(C)C)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A21 compound treatment 216720.0 38200.0 1.02 186840.0 -10200.0 -0.28 0.5282 0.4989 3558413 ACon1_000659 C[C@]1(O)CC[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](COC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A22 compound treatment 16120.0 -162000.0 -4.34 13360.0 -184000.0 -4.97 -6.5869 -0.9977 3553177 ACon1_000660 CC(=C)C(=O)O[C@H]1C[C@@]2(C)OC(=CC2=O)/C(=C\[C@H]3OC(=O)C(=C)C31)/COC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A23 compound treatment 218920.0 40400.0 1.08 205160.0 8150.0 0.22 0.9206 0.8342 3558349 ACon1_000661 CCC(C)C(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(=O)CC(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 A24 compound treatment 216040.0 37500.0 1.0 207880.0 10900.0 0.29 0.9182 0.8774 3559855 ACon1_000662 CC/C=C\C=C\C(O)C/C=C\CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B01 compound treatment 256280.0 77800.0 2.08 242120.0 45100.0 1.22 2.3347 0.9678 3558522 ACon1_000663 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3C[C@H](O)[C@@](C)(O)[C@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B02 compound treatment 10520.0 -168000.0 -4.49 9720.0 -187000.0 -5.07 -6.7625 -0.9982 3558331 ACon1_000664 CC1OC(OC2C(O)C(O)COC2OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC65C)C(=O)O)C3(C)CO)C(O)C(OC8OCC(OC(=O)C)C(OC(=O)C)C8O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B03 compound treatment 45040.0 -133000.0 -3.57 38240.0 -159000.0 -4.3 -5.5636 -0.9957 3558658 ACon1_000665 C[C@@H]1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C(=C)C)[C@@](C)(O)C(=O)[C@H]3O[C@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B04 compound treatment 214520.0 36000.0 0.96 194200.0 -2810.0 -0.08 0.6275 0.6492 3557543 ACon1_000666 CC(OC1OC(CO)C(O)C(O)C1O)/C=C/C2(O)C(C)CC(O)CC2(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B05 compound treatment 207760.0 29300.0 0.78 218200.0 21200.0 0.57 0.9591 0.9883 3558677 ACon1_000667 C[C@@]1(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC[C@@]3(C)[C@H](CCC4=CCOC4=O)C(=C)CC[C@H]13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B06 compound treatment 241320.0 62800.0 1.68 200960.0 3950.0 0.11 1.2638 0.7506 3559891 ACon1_000668 CC(CO[C@@H]1O[C@H](COC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H](O)[C@H](O)[C@H]1O)C3(O)COC(=O)C3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B07 compound treatment 191680.0 13200.0 0.35 178920.0 -18100.0 -0.49 -0.097 -0.1607 3558735 ACon1_000669 CC1CCC2(C)C(CCC=C2C(=O)O)C1(C)CCC3=CC(=O)OC3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B08 compound treatment 171000.0 -7500.0 -0.2 174000.0 -23000.0 -0.62 -0.5823 -0.8897 3557836 ACon1_000670 COc1cc(/C=C/C(=O)O[C@@H]2[C@@H](CO[C@@H]3OC[C@](O)(CO)[C@H]3O)O[C@@H](OCCc4ccc(O)c(O)c4)[C@H](O)[C@H]2O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B09 compound treatment 186760.0 8260.0 0.22 186040.0 -11000.0 -0.3 -0.0537 -0.1451 3558686 ACon1_000671 COc1cc(/C=C/C(=O)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2OC(=O)\C=C\c4cc(OC)c(O)c(OC)c4)cc(OC)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B10 compound treatment 174760.0 -3740.0 -0.1 178560.0 -18500.0 -0.5 -0.4239 -0.8321 1417265 ACon1_000672 OC1CCn2c1nc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B11 compound treatment 21480.0 -157000.0 -4.2 20200.0 -177000.0 -4.79 -6.3546 -0.9979 3557345 ACon1_000673 CC(=O)c1c(O)cc(O)c(C(=O)C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B12 compound treatment 177720.0 -776.0 -0.02 184160.0 -12900.0 -0.35 -0.2607 -0.748 3558110 ACon1_000674 COc1cc(/C=C/c2ccccc2)cc(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B13 mock treatment 182520.0 4020.0 0.11 200080.0 3070.0 0.08 0.1348 0.9918 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B14 mock treatment 168080.0 -10400.0 -0.28 182480.0 -14500.0 -0.39 -0.4752 -0.9857 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B15 compound treatment 178080.0 -416.0 -0.01 178840.0 -18200.0 -0.49 -0.3557 -0.7229 3559744 ACon1_000675 CC(CCO)CC[C@@H]1C(=C)CC[C@@H]2[C@@](C)(CCC[C@@]12C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B16 compound treatment 96840.0 -81700.0 -2.18 22000.0 -175000.0 -4.74 -4.8948 -0.9382 3553396 ACon1_000676 CC(=O)OCC1(C)CC2[C@]3(CO[C@]42CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]3O)[C@@H](O)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B17 compound treatment 200040.0 21500.0 0.58 195640.0 -1370.0 -0.04 0.3812 0.6602 3489715 ACon1_000677 CC1CCC2(CCC3(C(=O)O)C(=CCC4C5(C)CCC(OC6OC(C)C(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1C)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B18 compound treatment 183640.0 5140.0 0.14 172640.0 -24400.0 -0.66 -0.3693 -0.5479 3557359 ACon1_000678 CC(C)[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)n4c1nc5ccccc5c4=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B19 compound treatment 194280.0 15800.0 0.42 170320.0 -26700.0 -0.72 -0.2124 -0.2538 3558569 ACon1_000679 CC1=C(CCC2=CC(O)OC2=O)[C@@]3(C)CCC[C@@]4(C)[C@@H]3C(OC4=O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B20 compound treatment 178720.0 224.0 0.01 207760.0 10700.0 0.29 0.21 0.7215 3557575 ACon1_000680 OCCc1ccc(O)c(OC2OC(CO)C(O)C(O)C2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B21 compound treatment 199400.0 20900.0 0.56 202120.0 5110.0 0.14 0.4932 0.8562 3557374 ACon1_000681 C/C=C/C=C/C1C=CC2CC(C)CCC2C1(C)\C(=C/3\C(=O)NC(C(C)O)C3=O)\O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B22 compound treatment 189520.0 11000.0 0.29 222960.0 25900.0 0.7 0.7052 0.9257 3558646 ACon1_000682 CC(C)(O)CCC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(CC(O)C(OC5OC(CO)C(O)C(O)C5O)C4(C)C)C3(C)C(=O)CC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B23 compound treatment 204960.0 26500.0 0.71 198800.0 1790.0 0.05 0.5348 0.7537 3558270 ACon1_000683 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@@H](O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H]2OC(=O)/C=C/c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 B24 compound treatment 226760.0 48300.0 1.29 217280.0 20300.0 0.55 1.3009 0.9274 3558889 ACon1_000684 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)OC7OC(CO)C(O)C(O)C7O)C2(C)C)[C@H](O)[C@@H](O)[C@@H]1OC8OC(CO)C(O)C(O)C8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C01 compound treatment 199400.0 20900.0 0.56 210560.0 13500.0 0.37 0.6547 0.9791 3558360 ACon1_000685 COC(=O)[C@]1(C)CC[C@H](OC(=O)C)[C@@]2(C)C1C[C@@H](OC(=O)C)C3=C2CC[C@](C)(C=C)[C@@H]3OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C02 compound treatment 17520.0 -161000.0 -4.31 13000.0 -184000.0 -4.98 -6.5673 -0.9974 3558319 ACon1_000686 C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CCC3=C2)c6ccc(=O)oc6)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C03 compound treatment 170280.0 -8220.0 -0.22 171960.0 -25100.0 -0.68 -0.635 -0.8906 3558457 ACon1_000687 CC(CC[C@@]1(C)[C@H](C)CC[C@]2(C)C1CCC=C2CO)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C04 compound treatment 180960.0 2460.0 0.07 188120.0 -8890.0 -0.24 -0.1236 -0.4953 3553465 ACon1_000688 CC(C)(O)[C@@H]1CC[C@]2(CO)[C@@H](O)CC[C@](C)(O)[C@H]2[C@@H]1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C05 compound treatment 104560.0 -73900.0 -1.98 104160.0 -92900.0 -2.51 -3.1759 -0.993 3558579 ACon1_000689 COc1cc2OC(CC(=O)c2c(O)c1OC)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C06 compound treatment 190320.0 11800.0 0.32 187120.0 -9890.0 -0.27 0.0343 0.0827 3554662 ACon1_000690 COC(=O)C1(Cc2ccc(O)cc2)OC(=O)C(=C1c3ccc(O)cc3)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C07 compound treatment 168400.0 -10100.0 -0.27 175480.0 -21500.0 -0.58 -0.6032 -0.9388 3558617 ACon1_000691 COC(=O)C1=COC(O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OCCc4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C08 compound treatment 168720.0 -9780.0 -0.26 188440.0 -8570.0 -0.23 -0.349 -0.9982 3559200 ACon1_000692 COc1cc2occ(c3ccc4OCOc4c3)c(=O)c2c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C09 compound treatment 163960.0 -14500.0 -0.39 167800.0 -29200.0 -0.79 -0.8342 -0.9465 3554819 ACon1_000693 COc1cc(=O)oc(/C(=C/C(=C/C(=C/C2(C)OC(C)C3(C)OC32)/C)/C)/C)c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C10 compound treatment 15320.0 -163000.0 -4.36 14240.0 -183000.0 -4.95 -6.5852 -0.998 3558246 ACon1_000694 CC(C)C(=O)c1c(O)cc2OC(C)(C)C(CC=C(C)C)Cc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C11 mock treatment 179880.0 1380.0 0.04 174760.0 -22300.0 -0.6 -0.3998 -0.6624 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C12 mock treatment 174760.0 -3740.0 -0.1 178560.0 -18500.0 -0.5 -0.4239 -0.8321 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C13 compound treatment 171600.0 -6900.0 -0.18 181040.0 -16000.0 -0.43 -0.4362 -0.9279 3558047 ACon1_000695 COc1cc(CCO)ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C14 compound treatment 171600.0 -6900.0 -0.18 185160.0 -11900.0 -0.32 -0.3573 -0.9654 3614417 ACon1_000696 COC1CC(OC(O)C(O)C(O)C(O)C(O)CO)c2c(O)c3c(=O)oc(C)cc3cc2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C15 mock treatment 180280.0 1780.0 0.05 182840.0 -14200.0 -0.38 -0.2376 -0.6144 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C16 mock treatment 169720.0 -8780.0 -0.23 184560.0 -12500.0 -0.34 -0.4044 -0.9844 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C17 compound treatment 188320.0 9820.0 0.26 187480.0 -9530.0 -0.26 0.0033 0.0091 3558236 ACon1_000697 CC(C)C1(CC12)C(=O)CC2(C)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C18 compound treatment 16920.0 -162000.0 -4.32 14040.0 -183000.0 -4.95 -6.5588 -0.9977 3557265 ACon1_000698 CC(=CCC/C(=C/CC/C(=C/Cc1c(C)cc(O)cc1O)/C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C19 compound treatment 155080.0 -23400.0 -0.63 143440.0 -53600.0 -1.45 -1.4684 -0.9295 3558297 ACon1_000699 CC(C)c1cc2CCC3C(C)(C)CCC[C@]3(C(=O)O)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C20 compound treatment 182800.0 4300.0 0.12 178560.0 -18500.0 -0.5 -0.2718 -0.5303 3558260 ACon1_000700 CC(C)C(O)(C(C)O)C(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C21 compound treatment 14720.0 -164000.0 -4.38 14120.0 -183000.0 -4.95 -6.5988 -0.9981 3558324 ACon1_000701 CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C22 compound treatment 190720.0 12200.0 0.33 164000.0 -33000.0 -0.89 -0.4008 -0.4211 3558258 ACon1_000702 C[C@H](O)C1=CC2(CC[C@H]3[C@@H]2[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C23 compound treatment 180200.0 1700.0 0.05 146840.0 -50200.0 -1.36 -0.9282 -0.683 3555893 ACon1_000703 OC[C@H]1O[C@@H](Oc2cc(C(=O)O)c(O)c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 C24 compound treatment 185200.0 6700.0 0.18 194880.0 -2130.0 -0.06 0.086 0.4564 3557293 ACon1_000704 COC(=O)c1cccc2oc3cc(CO)cc(O)c3c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D01 compound treatment 27680.0 -151000.0 -4.03 27080.0 -170000.0 -4.6 -6.1056 -0.9979 3557722 ACon1_000705 COc1ccc2ccc(=O)oc2c1CC(O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D02 compound treatment 195280.0 16800.0 0.45 211520.0 14500.0 0.39 0.5952 0.9978 3553508 ACon1_000706 CC(C)C(=O)O[C@@H]1[C@@H](OC(=O)C)[C@@H](OC(=O)C)C(C)(C)/C=C/[C@@](C)(O)C(=O)[C@@]2(O)[C@H](OC(=O)C)[C@@](C)(OC(=O)C)[C@H](OC(=O)C)[C@@H]2[C@H]3OC(=O)CC[C@]31OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D03 compound treatment 204000.0 25500.0 0.68 197760.0 748.0 0.02 0.4967 0.7278 3558643 ACon1_000707 COc1cc(OC2OC(COC3OCC(O)(CO)C3O)C(O)C(O)C2O)c4c(cc(=O)oc4c1)c5ccc(O)c(O)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D04 compound treatment 250640.0 72100.0 1.93 226360.0 29300.0 0.79 1.9264 0.9231 1279467 ACon1_000708 COC(=O)C(Cc1ccccc1)NC(=O)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D05 compound treatment 231760.0 53300.0 1.42 274600.0 77600.0 2.1 2.4927 0.9821 3614423 ACon1_000709 COC(=O)C1=CC=CC(CC(O)C(=O)O)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D06 compound treatment 231600.0 53100.0 1.42 224240.0 27200.0 0.74 1.5256 0.9533 3558535 ACon1_000710 C[C@@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C2(C)C)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D07 compound treatment 189280.0 10800.0 0.29 201160.0 4150.0 0.11 0.2834 0.9155 3614426 ACon1_000711 CC1CC(=O)C2=C(O1)OC3(C)CCC4(O)C(C)(C)C5OC5C(=O)C4(C)C3C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D08 compound treatment 178200.0 -296.0 -0.01 193720.0 -3290.0 -0.09 -0.0686 -0.767 3554252 ACon1_000712 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCC(O)COP(=O)(O)OCC[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D09 compound treatment 178880.0 384.0 0.01 162520.0 -34500.0 -0.93 -0.653 -0.6993 3558720 ACon1_000713 COc1cc(/C=C/c2cc(O)cc(O)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D10 compound treatment 185680.0 7180.0 0.19 238600.0 41600.0 1.13 0.932 0.816 3554771 ACon1_000714 COc1c(O)ccc2C([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4cc(C)cc(O)c4C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D11 mock treatment 219320.0 40800.0 1.09 219280.0 22300.0 0.6 1.1984 0.9608 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D12 mock treatment 211840.0 33300.0 0.89 201840.0 4830.0 0.13 0.7231 0.8022 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D13 compound treatment 196760.0 18300.0 0.49 220120.0 23100.0 0.63 0.7878 0.9925 3614428 ACon1_000715 COC(=O)c1c(C)cc2CC3(Oc2c(C)c1=O)C(C)CCC(C(C)(C)O)C3(C)CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D14 compound treatment 231040.0 52500.0 1.41 204920.0 7910.0 0.21 1.1452 0.8055 3553648 ACon1_000716 CC(C)CC1NC(=O)C2CCCN2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D15 mock treatment 211000.0 32500.0 0.87 215760.0 18700.0 0.51 0.9737 0.9672 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D16 mock treatment 225040.0 46500.0 1.24 200560.0 3550.0 0.1 0.9483 0.7594 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D17 compound treatment 186560.0 8060.0 0.22 238680.0 41700.0 1.13 0.9502 0.8273 3558202 ACon1_000717 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)C)[C@H]1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D18 compound treatment 195520.0 17000.0 0.46 234440.0 37400.0 1.01 1.0385 0.9348 3558526 ACon1_000718 COc1ccc2ccc(=O)oc2c1CC(O)C(C)(C)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D19 compound treatment 226840.0 48300.0 1.29 211440.0 14400.0 0.39 1.1906 0.8814 3614429 ACon1_000719 COc1cccc2oc3OC=C(CO)C=C(C(=O)O)c3c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D20 compound treatment 201160.0 22700.0 0.61 178680.0 -18300.0 -0.5 0.0777 0.0992 3558603 ACon1_000720 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)O[C@@H]6OC[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D21 compound treatment 204080.0 25600.0 0.68 213560.0 16500.0 0.45 0.8007 0.9789 3614430 ACon1_000721 C[C@@H]1C[C@H]2OC(=O)[C@@]3(C)CCC[C@](C)(C23)[C@@]1(O)CCC4=CC(=O)OC4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D22 compound treatment 168040.0 -10500.0 -0.28 206720.0 9710.0 0.26 -0.0119 -0.0311 3558751 ACon1_000722 COc1ccc(cc1OC)[C@@H]2O[C@H]([C@@H](C)[C@@H]2C)c3ccc(OC)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D23 compound treatment 220120.0 41600.0 1.11 215960.0 18900.0 0.51 1.15 0.9381 3554692 ACon1_000723 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OC[C@H]3O[C@@H](OCCc4ccc(O)cc4)[C@H](OC(=O)CC5\C(=C\C)\C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)OC=C5C(=O)OC)[C@@H](O)[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 D24 compound treatment 60400.0 -118000.0 -3.16 43120.0 -154000.0 -4.17 -5.1797 -0.9907 3554061 ACon1_000724 CC1CCC/C=C/C(=O)c2c(O)cc(O)cc2CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E01 mock treatment 174520.0 -3980.0 -0.11 190640.0 -6370.0 -0.17 -0.1972 -0.973 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E02 mock treatment 204920.0 26400.0 0.71 205240.0 8230.0 0.22 0.6573 0.8869 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E03 compound treatment 199560.0 21100.0 0.56 212640.0 15600.0 0.42 0.6976 0.99 3558404 ACon1_000725 CC(C)c1ccc2c(CCC3[C@@](C)(CCC[C@@]32C)C(=O)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E04 compound treatment 177840.0 -656.0 -0.02 184160.0 -12900.0 -0.35 -0.2584 -0.7418 3558499 ACon1_000726 OCC1OC(Oc2ccc(/C=C/C(=O)OC3COC(OCC4OC(OC(C#N)c5ccccc5)C(O)C(O)C4O)C(O)C3O)cc2)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E05 compound treatment 154480.0 -24000.0 -0.64 162480.0 -34500.0 -0.93 -1.1153 -0.9832 3558134 ACon1_000727 Cc1c(O)cc2OC(CC(=O)c2c1O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E06 compound treatment 173320.0 -5180.0 -0.14 174400.0 -22600.0 -0.61 -0.5308 -0.8457 2082654 ACon1_000728 COc1ccc(cc1OC)c2oc3c(OC)c(OC)c(OC)c(O)c3c(=O)c2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E07 compound treatment 153560.0 -24900.0 -0.67 176840.0 -20200.0 -0.55 -0.8578 -0.9951 3557964 ACon1_000729 CC(=O)OC1C(O)C(O)C(CO)OC1Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E08 compound treatment 42480.0 -136000.0 -3.64 22200.0 -175000.0 -4.73 -5.9191 -0.9916 3614436 ACon1_000730 COc1ccc(cc1)c2coc3c(CC=C(C)C)c(O)c(OC)cc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E09 mock treatment 147360.0 -31100.0 -0.83 161520.0 -35500.0 -0.96 -1.2683 -0.9975 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E10 mock treatment 156400.0 -22100.0 -0.59 174160.0 -22900.0 -0.62 -0.8554 -0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E11 compound treatment 57480.0 -121000.0 -3.24 47120.0 -150000.0 -4.06 -5.1583 -0.9937 1102884 ACon1_000731 Cc1cc(O)c(O)c(Oc2cc(C)cc(O)c2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E12 compound treatment 111800.0 -66700.0 -1.78 111720.0 -85300.0 -2.31 -2.8943 -0.9919 3614439 ACon1_000732 Cc1cc(O)c(C)c2OC(=O)c3c(C)cc(O)c(C)c3Oc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E13 compound treatment 166000.0 -12500.0 -0.33 176240.0 -20800.0 -0.56 -0.634 -0.9691 3558045 ACon1_000733 O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)/C=C/c2ccccc2)[C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E14 compound treatment 167400.0 -11100.0 -0.3 199800.0 2790.0 0.08 -0.1565 -0.511 3557896 ACon1_000734 CC1OC(OCC2OC(Oc3cc(O)c4c(=O)c(coc4c3)c5ccc(O)cc5)C(O)C(O)C2O)C(O)C(O)C1OC6OC(CO)C(O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E15 compound treatment 164720.0 -13800.0 -0.37 180920.0 -16100.0 -0.44 -0.5686 -0.9965 3555889 ACon1_000735 OC[C@H]1O[C@@H](OC/C/2=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](O)C/C(=C\CC2)/C=O)[C@H](OC(=O)Cc4ccc(O)cc4)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E16 compound treatment 143840.0 -34700.0 -0.93 155160.0 -41900.0 -1.13 -1.4567 -0.995 3557786 ACon1_000736 CC1(C)[C@@H](O)C(=O)C[C@@]2(C)C1CC[C@@]3(C)O[C@](C)(CCC32)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E17 mock treatment 158440.0 -20100.0 -0.54 175320.0 -21700.0 -0.59 -0.7946 -0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E18 mock treatment 148800.0 -29700.0 -0.79 166360.0 -30700.0 -0.83 -1.1485 -0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E19 compound treatment 155080.0 -23400.0 -0.63 177880.0 -19100.0 -0.52 -0.8091 -0.9955 3558389 ACon1_000737 CC(C)C1CC=C(C)C(O)CCC(=C)CC1OC2OC(COC(=O)C)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E20 compound treatment 168160.0 -10300.0 -0.28 224640.0 27600.0 0.75 0.3334 0.4181 3558256 ACon1_000738 OC[C@H]1O[C@@H](Oc2ccc(/C=C/C(=O)O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E21 compound treatment 174200.0 -4300.0 -0.11 182960.0 -14100.0 -0.38 -0.3503 -0.8814 3558369 ACon1_000739 C[C@@H]1C[C@H]2OC(=O)[C@@]3(C)CCC[C@](C)(C23)[C@@]1(O)CCc4ccoc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E22 compound treatment 108080.0 -70400.0 -1.88 91600.0 -105000.0 -2.85 -3.3498 -0.9797 3558332 ACon1_000740 Oc1ccc(cc1O)C2OC[C@@H]3[C@H](OC[C@H]23)c4ccc5OCOc5c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E23 compound treatment 181040.0 2540.0 0.07 199760.0 2750.0 0.07 0.1007 0.999 3558345 ACon1_000741 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](OC(=O)C)[C@@H]2OC(=O)C)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 E24 compound treatment 176640.0 -1860.0 -0.05 184920.0 -12100.0 -0.33 -0.2666 -0.8051 3557578 ACon1_000742 OCC1OC(C(O)C(O)C1O)c2c(O)cc3oc(cc(=O)c3c2O)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F01 mock treatment 186400.0 7900.0 0.21 190640.0 -6370.0 -0.17 0.0275 0.1008 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F02 mock treatment 180040.0 1540.0 0.04 199800.0 2790.0 0.08 0.0826 0.9597 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F03 compound treatment 191080.0 12600.0 0.34 189000.0 -8010.0 -0.22 0.0846 0.2114 3558651 ACon1_000743 C[C@@H]1C[C@@H](O)C2[C@@](C)(CO)CCC[C@]2(C)[C@@]1(O)CCc3ccoc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F04 compound treatment 245400.0 66900.0 1.79 204760.0 7750.0 0.21 1.4138 0.7846 3614448 ACon1_000744 COC(CC(OC)c1c(O)cc2cc(C)oc(=O)c2c1O)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F05 compound treatment 16120.0 -162000.0 -4.34 15720.0 -181000.0 -4.91 -6.5417 -0.9981 3552924 ACon1_000745 C[C@H](CCC(=C)[C@@H](C)C(=O)O)[C@H]1CCC2(C)C3=C(C[C@H](O)[C@]12C)[C@@]4(C)CC[C@@H](OC(=O)CC(=O)O)C(C)(C)C4CC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F06 compound treatment 217520.0 39000.0 1.04 188440.0 -8570.0 -0.23 0.574 0.5368 3554676 ACon1_000746 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCc3ccc(OC(=O)C[C@H]4\C(=C/C)\[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)OC=C4C(=O)OC)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F07 compound treatment 15680.0 -163000.0 -4.36 16160.0 -181000.0 -4.9 -6.5416 -0.9983 3554523 ACon1_000747 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)\C(=C/C)\C)C1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F08 compound treatment 129520.0 -49000.0 -1.31 161320.0 -35700.0 -0.97 -1.6096 -0.9888 3558636 ACon1_000748 CC(O)CCC1=CC[C@H]2OC(=O)C(=C)[C@@H]2CC1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F09 mock treatment 161160.0 -17300.0 -0.46 165840.0 -31200.0 -0.84 -0.9246 -0.9602 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F10 mock treatment 153520.0 -25000.0 -0.67 174440.0 -22600.0 -0.61 -0.9045 -0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F11 compound treatment 181280.0 2780.0 0.07 180440.0 -16600.0 -0.45 -0.2646 -0.5818 3558527 ACon1_000749 COc1ccc2ccc(=O)oc2c1C(OC(=O)C)C(=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F12 compound treatment 14760.0 -164000.0 -4.38 15520.0 -181000.0 -4.91 -6.5713 -0.9984 3558182 ACon1_000750 C/C=C(\C)/C(=O)O[C@H]1[C@H](OC(=O)C)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H]6O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@]43C)C2CC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F13 compound treatment 75240.0 -103000.0 -2.76 45480.0 -152000.0 -4.1 -4.8538 -0.9815 3559736 ACon1_000751 CC(C)C(=O)O[C@@H]1c2c(C)coc2C(=O)[C@@H]3[C@@H](OC(=O)C=C(C)C)[C@H](O)C[C@H](C)[C@@]13C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F14 compound treatment 124240.0 -54300.0 -1.45 137160.0 -59900.0 -1.62 -2.172 -0.9985 3553501 ACon1_000752 CC(C)[C@]1(O)CC2=CC[C@H](OC1=O)/C(=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](C2)OC(=O)/C(=C/CO)/CO)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F15 compound treatment 165720.0 -12800.0 -0.34 183720.0 -13300.0 -0.36 -0.4961 -0.9997 3559723 ACon1_000753 C/C(=C\CO)/C(=O)O[C@@H]1C\C(=C\CC[C@@]2(CO)OC2[C@H]3OC(=O)C(=C)C31)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F16 compound treatment 178200.0 -296.0 -0.01 210800.0 13800.0 0.37 0.2583 0.6919 3558093 ACon1_000754 COC1CC(O[C@H]2CC[C@]3(C)C4[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(C)[C@H](CC[C@]5(O)C4CC=C3C2)C(=O)C)OC(C)C1OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F17 mock treatment 163880.0 -14600.0 -0.39 205400.0 8390.0 0.23 -0.1159 -0.2563 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F18 mock treatment 167920.0 -10600.0 -0.28 189880.0 -7130.0 -0.19 -0.3366 -0.9827 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F19 compound treatment 183720.0 5220.0 0.14 192520.0 -4490.0 -0.12 0.0128 0.0692 3554275 ACon1_000755 CCCCCC1=C(O)/C(=C/C(=O)O)/OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F20 compound treatment 170520.0 -7980.0 -0.21 170640.0 -26400.0 -0.71 -0.6557 -0.88 3558634 ACon1_000756 CCC(C)(O)CC(=O)O[C@H]/1C[C@@H]2[C@H](OC(=O)C2=C)[C@@H]3O[C@]3(C)CC\C=C1/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F21 compound treatment 174560.0 -3940.0 -0.11 176520.0 -20500.0 -0.55 -0.4667 -0.8266 3614460 ACon1_000757 CCC(C)/C=C(\C)/C=C/C1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F22 compound treatment 207320.0 28800.0 0.77 161120.0 -35900.0 -0.97 -0.1419 -0.1144 3555003 ACon1_000758 COc1cc(oc(=O)c1)c2c(C)cc(O)cc2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F23 compound treatment 169160.0 -9340.0 -0.25 182400.0 -14600.0 -0.4 -0.4563 -0.9754 3557852 ACon1_000759 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@](C)(C5CC[C@]43C)C(=O)O)C2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 F24 compound treatment 184440.0 5940.0 0.16 172960.0 -24100.0 -0.65 -0.348 -0.5192 3558059 ACon1_000760 COc1ccc(cc1)C2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](OC5OCC(O)(CO)C5O)[C@H](O)[C@H]4O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G01 compound treatment 170520.0 -7980.0 -0.21 206920.0 9910.0 0.27 0.0388 0.1132 3558424 ACon1_000761 COc1ccc(cc1)c2coc3c(OC)c(OC)cc(OC4OC(CO)C(O)C(O)C4OC5OCC(O)C(O)C5O)c3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G02 compound treatment 185680.0 7180.0 0.19 177520.0 -19500.0 -0.53 -0.2373 -0.4225 3558440 ACon1_000762 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H](C(=C)CO)[C@@](C)(C[C@@H]2O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G03 mock treatment 156640.0 -21900.0 -0.58 204040.0 7030.0 0.19 -0.2789 -0.4536 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G04 mock treatment 157760.0 -20700.0 -0.55 162520.0 -34500.0 -0.93 -1.0525 -0.9691 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G05 compound treatment 181520.0 3020.0 0.08 190720.0 -6290.0 -0.17 -0.0633 -0.3355 3552674 ACon1_000763 C[C@@H]1CC(=O)[C@]2(COC(=O)C)[C@H](CC[C@H](O)[C@@]32CO3)[C@]41C[C@H](OC4=O)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G06 compound treatment 171440.0 -7060.0 -0.19 191960.0 -5050.0 -0.14 -0.2302 -0.9875 3557361 ACon1_000764 COc1cc(OC)c2c(=O)oc(CC(O)CC(=O)C)cc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G07 compound treatment 158880.0 -19600.0 -0.52 192840.0 -4170.0 -0.11 -0.4509 -0.8401 1080935 ACon1_000765 Cc1c(O)cc2OC(CC(=O)c2c1O)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G08 compound treatment 161280.0 -17200.0 -0.46 177800.0 -19200.0 -0.52 -0.6934 -0.9982 3614466 ACon1_000766 COc1cc(O)c-2c(CCc3cc(OC)c(OC)cc32)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G09 compound treatment 141680.0 -36800.0 -0.98 172960.0 -24100.0 -0.65 -1.1568 -0.9798 3557989 ACon1_000767 CC(C)(O)C1Oc2cc3occ(c4ccc(O)cc4)c(=O)c3c(O)c2C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G10 compound treatment 16400.0 -162000.0 -4.34 17720.0 -179000.0 -4.85 -6.4981 -0.9984 3559169 ACon1_000768 COc1ccc(cc1)C(O)CNC(=O)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G11 compound treatment 169080.0 -9420.0 -0.25 188440.0 -8570.0 -0.23 -0.3422 -0.9992 3558069 ACon1_000769 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C)[C@H]3CCC(CO)[C@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G12 compound treatment 160880.0 -17600.0 -0.47 190520.0 -6490.0 -0.18 -0.4575 -0.9096 3555309 ACon1_000770 COc1cccc2C(=O)OC(c21)c3ccc4C(O)C(C)CC(=O)c4c3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G13 compound treatment 138760.0 -39700.0 -1.06 172560.0 -24500.0 -0.66 -1.2197 -0.974 3558151 ACon1_000771 OC[C@H]1O[C@@H](OC/C/2=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](O)C/C(=C\CC2)/C=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G14 compound treatment 156760.0 -21700.0 -0.58 194640.0 -2370.0 -0.06 -0.4565 -0.7805 3557929 ACon1_000772 C[C@@]12C[C@@H](O)[C@@H]3C[C@@]2(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@]3(COC(=O)c5ccccc5)C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G15 compound treatment 156000.0 -22500.0 -0.6 199640.0 2630.0 0.07 -0.3752 -0.6192 3558123 ACon1_000773 COc1ccc(/C=C/C(=O)O[C@]2(C)CCC3[C@@H]2[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G16 compound treatment 158600.0 -19900.0 -0.53 181360.0 -15700.0 -0.42 -0.676 -0.9936 3557915 ACon1_000774 COc1c(OC2OC(CO)C(O)C(O)C2O)ccc(O)c1C(=O)OCc3ccccc3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G17 compound treatment 157040.0 -21500.0 -0.57 172880.0 -24100.0 -0.65 -0.8678 -0.9979 3614471 ACon1_000775 COc1cc(/C=C/C(=O)NCC(O)c2ccc(O)cc2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G18 compound treatment 168200.0 -10300.0 -0.28 187240.0 -9770.0 -0.26 -0.3818 -0.9998 3558265 ACon1_000776 COc1ccc(cc1)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G19 mock treatment 179360.0 864.0 0.02 177920.0 -19100.0 -0.52 -0.3491 -0.6748 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G20 mock treatment 168320.0 -10200.0 -0.27 168200.0 -28800.0 -0.78 -0.744 -0.9006 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G21 compound treatment 192960.0 14500.0 0.39 226400.0 29400.0 0.8 0.8361 0.9451 3558300 ACon1_000777 CC(CO)C(=O)O[C@H]1C[C@@]2(C)[C@H](O)CCC(=O)[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G22 compound treatment 162480.0 -16000.0 -0.43 168560.0 -28500.0 -0.77 -0.8476 -0.9617 1047948 ACon1_000778 COc1cc(cc(OC)c1OC)C2OCC3C(OCC23)c4cc(OC)c(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G23 compound treatment 15600.0 -163000.0 -4.36 12840.0 -184000.0 -4.99 -6.6067 -0.9977 3558322 ACon1_000779 CC(C)c1cc2C(O)C[C@H]3C(C)(C)CCC[C@]3(C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 G24 compound treatment 181600.0 3100.0 0.08 196200.0 -812.0 -0.02 0.0432 0.5025 3558519 ACon1_000780 OCC1C(O)CC2C1C(=O)OCC2=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H01 compound treatment 180920.0 2420.0 0.06 207360.0 10300.0 0.28 0.2439 0.8483 3614474 ACon1_000781 COc1c2C(=O)OCc2c(C)c3OC4(C)CC(O)C5(O)C(C)(CCC(=O)OC5(C)C)C4Cc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H02 compound treatment 15240.0 -163000.0 -4.37 14640.0 -182000.0 -4.94 -6.579 -0.9981 3558708 ACon1_000782 C[C@@H]/1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C(=C)C)[C@@](C)(O)C(=O)/C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H03 mock treatment 179400.0 904.0 0.02 186680.0 -10300.0 -0.28 -0.1807 -0.6436 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H04 mock treatment 208840.0 30300.0 0.81 175040.0 -22000.0 -0.59 0.1533 0.1524 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H05 compound treatment 156080.0 -22400.0 -0.6 183840.0 -13200.0 -0.36 -0.6761 -0.9692 3552202 ACon1_000783 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](CC(O)C3=CCOC3=O)C(=C)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H06 compound treatment 15600.0 -163000.0 -4.36 17200.0 -180000.0 -4.87 -6.5232 -0.9985 3558285 ACon1_000784 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@@H](O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)[C@H](O)C[C@]5(C)C4CC[C@]23C)O[C@@]%101CCC(C)CO%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H07 compound treatment 150920.0 -27600.0 -0.74 181160.0 -15900.0 -0.43 -0.825 -0.9668 3558479 ACon1_000785 C[C@@]1(CCC2=C(C1)C(=O)CC3[C@@](C)(CCC[C@@]32C)C(=O)O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H08 compound treatment 171240.0 -7260.0 -0.19 215240.0 18200.0 0.49 0.2117 0.3992 3553528 ACon1_000786 CC(C)C(=O)OC/C(=C/CCC(=C)C1CC=C(CO)C(C1)OC(=O)C(C)C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H09 compound treatment 160560.0 -17900.0 -0.48 187280.0 -9730.0 -0.26 -0.5256 -0.9602 3558737 ACon1_000787 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H10 compound treatment 154760.0 -23700.0 -0.63 171640.0 -25400.0 -0.69 -0.9347 -0.9992 3559235 ACon1_000788 CC1OC(O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)OC7OC(CO)C(OC8OC(CO)C(O)C(O)C8O)C(O)C7O)C2(C)C)C(O)C(O)C1OC9OCC(O)(COC%10OCC(O)C(OC%11OCC(OC%12OCC(O)(CO)C%12O)C(O)C%11O)C%10O)C9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H11 compound treatment 174440.0 -4060.0 -0.11 184800.0 -12200.0 -0.33 -0.3105 -0.8923 3557942 ACon1_000789 CC1CCC2(C)C(CC(=O)C=C2C)C1(C)CC/C(=C\C(=O)O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H12 compound treatment 189720.0 11200.0 0.3 206640.0 9630.0 0.26 0.3966 0.9975 3552656 ACon1_000790 C[C@@H]1C[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@]2(COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)c3ccccc3)[C@@H]4[C@@H](OC(=O)C)[C@]12OC4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H13 compound treatment 139200.0 -39300.0 -1.05 188720.0 -8290.0 -0.22 -0.902 -0.8392 1712662 ACon1_000791 COc1ccc2CC(=O)c3cc4OCOc4cc3CCN(C)Cc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H14 compound treatment 143800.0 -34700.0 -0.93 188800.0 -8210.0 -0.22 -0.8135 -0.8524 3557252 ACon1_000792 CC1CCC2C(C)(C)[C@@H](O)CC[C@]2(C)C31Cc4c(O3)c5CN(C(CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H15 compound treatment 159560.0 -18900.0 -0.51 183240.0 -13800.0 -0.37 -0.6218 -0.9886 3559760 ACon1_000793 COc1cc(OC)c2c(=O)c(OC)c(oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H16 compound treatment 151640.0 -26900.0 -0.72 204400.0 7390.0 0.2 -0.3665 -0.4915 3558095 ACon1_000794 COC1CC(O[C@H]2CC[C@]3(C)C4[C@H](OC(=O)C)[C@@H](OC(=O)/C(=C/C)/C)[C@]5(C)[C@H](CC[C@]5(O)[C@]4(O)CC=C3C2)C(=O)C)OC(C)C1OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H17 compound treatment 159640.0 -18900.0 -0.5 186800.0 -10200.0 -0.28 -0.5521 -0.9599 3557608 ACon1_000795 COC(=O)C1=CCC[C@@H]2[C@@]3(CC(OC3=O)c4ccoc4)[C@H](C)CC[C@]21C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H18 compound treatment 117600.0 -60900.0 -1.63 146840.0 -50200.0 -1.36 -2.1123 -0.9959 3558016 ACon1_000796 COc1c(oc2c(OC)c(O)cc(O)c2c1=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H19 mock treatment 167680.0 -10800.0 -0.29 169520.0 -27500.0 -0.74 -0.7309 -0.9153 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H20 mock treatment 151280.0 -27200.0 -0.73 167560.0 -29500.0 -0.8 -1.0786 -0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H21 compound treatment 175800.0 -2700.0 -0.07 167320.0 -29700.0 -0.8 -0.6194 -0.7675 3558356 ACon1_000797 CCC1C2O[C@H]3OC=C([C@H]4C=C[C@]2(OC1=O)[C@@H]34)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H22 compound treatment 161880.0 -16600.0 -0.44 184920.0 -12100.0 -0.33 -0.5458 -0.9887 3558238 ACon1_000798 CC(O)(C=C)C(O)CC1C(=C)CCC2C(C)(CCCC12C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H23 compound treatment 191040.0 12500.0 0.34 187440.0 -9570.0 -0.26 0.054 0.1274 3553600 ACon1_000799 CC(C)C1NC(=O)/C(=C/c2nc[nH]c2C(C)(C)C=C)/NC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 H24 compound treatment 178360.0 -136.0 0.0 190800.0 -6210.0 -0.17 -0.1215 -0.7223 3558108 ACon1_000800 CC1(C)[C@H]2C[C@@H]1C(=CC2)CO[C@@H]3O[C@H](CO[C@@H]4O[C@@H](CO)[C@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I01 compound treatment 180560.0 2060.0 0.06 192480.0 -4530.0 -0.12 -0.0477 -0.3547 3558341 ACon1_000801 COC(=O)C1=C[C@@H](O)[C@@H](O)[C@@H](C1)O[C@@H]2O[C@H](COC(=O)/C=C/c3ccccc3)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I02 compound treatment 193960.0 15500.0 0.41 204520.0 7510.0 0.2 0.4362 0.9465 3558497 ACon1_000802 CC1=CC(=O)C2=C(C)C[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]4[C@H](OC(=O)C4=C)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I03 compound treatment 150040.0 -28500.0 -0.76 188920.0 -8090.0 -0.22 -0.6931 -0.8751 3558461 ACon1_000803 CC(CC[C@@]1(C)[C@H](C)CC[C@]2(C)C1CCC=C2COC(=O)C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I04 compound treatment 164240.0 -14300.0 -0.38 237720.0 40700.0 1.1 0.5096 0.437 3558501 ACon1_000804 CC(OC1OC(CO)C(O)C(O)C1O)C2C(O)CC3C4CCC5=CC(=O)CCC5(C)C4CCC23C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I05 mock treatment 166800.0 -11700.0 -0.31 192320.0 -4690.0 -0.13 -0.311 -0.9212 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I06 mock treatment 162840.0 -15700.0 -0.42 187160.0 -9850.0 -0.27 -0.4847 -0.9763 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I07 compound treatment 163840.0 -14700.0 -0.39 195280.0 -1730.0 -0.05 -0.3104 -0.7861 3557857 ACon1_000805 COc1c2ccoc2c(OC)c3oc(CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(=O)c13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I08 compound treatment 207360.0 28900.0 0.77 239440.0 42400.0 1.15 1.3581 0.9813 3614493 ACon1_000806 COc1cc(O)c2c(=O)cc(oc2c1OC)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I09 compound treatment 149960.0 -28500.0 -0.76 194840.0 -2170.0 -0.06 -0.5813 -0.7593 3557926 ACon1_000807 CC1(C)C2CC(OC3OC(CO)C(O)C(O)C3O)C1(C)CC2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I10 compound treatment 139760.0 -38700.0 -1.04 206120.0 9110.0 0.25 -0.5583 -0.5242 3558796 ACon1_000808 COc1cc(O)c(OC)c2OC(CC(=O)c12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I11 compound treatment 158760.0 -19700.0 -0.53 189320.0 -7690.0 -0.21 -0.5205 -0.9172 3558071 ACon1_000809 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)/C=C/c3ccc(O)cc3)[C@H]4CCC(CO)[C@H]41 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I12 compound treatment 179800.0 1300.0 0.03 250320.0 53300.0 1.44 1.0451 0.724 2084711 ACon1_000810 CC(=CCc1c(O)ccc2ccc(=O)oc12)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I13 compound treatment 173440.0 -5060.0 -0.14 219040.0 22000.0 0.6 0.326 0.5332 3558138 ACon1_000811 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(COC(=O)/C=C/c5ccc(O)cc5)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I14 compound treatment 170920.0 -7580.0 -0.2 193680.0 -3330.0 -0.09 -0.2071 -0.9335 3555622 ACon1_000812 O[C@H]1[C@@H](O)[C@H](OC(=O)Cc2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1OC(=O)Cc3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I15 compound treatment 167600.0 -10900.0 -0.29 200280.0 3270.0 0.09 -0.1435 -0.4712 3558149 ACon1_000813 OC[C@H]1O[C@@H](OC/C/2=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H]4C/C(=C\CC2)/C(=O)O4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I16 compound treatment 159120.0 -19400.0 -0.52 193960.0 -3050.0 -0.08 -0.4249 -0.8096 3557723 ACon1_000814 CC1[C@@H]2CC/C(=C/CC/C(=C/[C@H]2OC1=O)/C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I17 compound treatment 184320.0 5820.0 0.16 219320.0 22300.0 0.6 0.5372 0.8613 3558279 ACon1_000815 C/C(=C\CCC(O)C(C)(C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)/CCC(C)(O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I18 compound treatment 161440.0 -17100.0 -0.46 188520.0 -8490.0 -0.23 -0.4852 -0.9497 3558214 ACon1_000816 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/[C@H](C/C=C(\C)/C[C@@H]2O)OC(=O)C(=C)[C@@H]3CCC(=C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=C)[C@@H]4C3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I19 compound treatment 194720.0 16200.0 0.43 234600.0 37600.0 1.02 1.0264 0.9278 3614503 ACon1_000817 CC1OC(=O)CC2C(=CC3(O)CC(C)(C)CC213)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I20 compound treatment 129000.0 -49500.0 -1.32 157560.0 -39500.0 -1.07 -1.6914 -0.9943 1072848 ACon1_000818 COc1c(oc2cc(O)cc(O)c2c1=O)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I21 mock treatment 187000.0 8500.0 0.23 179080.0 -17900.0 -0.49 -0.1824 -0.3403 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I22 mock treatment 203160.0 24700.0 0.66 210560.0 13500.0 0.37 0.7258 0.9616 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I23 compound treatment 53360.0 -125000.0 -3.35 60880.0 -136000.0 -3.69 -4.9729 -0.9988 3554830 ACon1_000819 COc1cc(c(OC)c2oc3cc(O)c(O)cc3c12)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 I24 compound treatment 175800.0 -2700.0 -0.07 197280.0 268.0 0.01 -0.0459 -0.6328 3558502 ACon1_000820 COc1cc2OCOc2cc1c3coc4cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)ccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J01 compound treatment 11120.0 -167000.0 -4.48 12920.0 -184000.0 -4.98 -6.6899 -0.9986 3553370 ACon1_000821 CC(=O)OC[C@@]12C[C@H](O)C(=C[C@H]2O[C@@H]3[C@H](O)[C@@H](OC(=O)C)[C@@]1(C)[C@@]43CO4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J02 compound treatment 226160.0 47700.0 1.27 218480.0 21500.0 0.58 1.3125 0.9367 3558605 ACon1_000822 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5[C@H](O)C[C@]43C)C2C1)C(=O)OC6OCC(OC7OCC(O)C(O)C7O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J03 compound treatment 180880.0 2380.0 0.06 202840.0 5830.0 0.16 0.1567 0.9205 3558664 ACon1_000823 CC(C(=O)O)[C@@]12CC[C@H](C)[C@H](CCC(=O)O)C(C)C2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J04 compound treatment 269000.0 90500.0 2.42 232200.0 35200.0 0.95 2.3854 0.9169 3559918 ACon1_000824 CC(=CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)[C@H](O)[C@H](Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J05 mock treatment 194280.0 15800.0 0.42 213880.0 16900.0 0.46 0.6214 0.9992 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J06 mock treatment 172640.0 -5860.0 -0.16 192520.0 -4490.0 -0.12 -0.1968 -0.9922 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J07 compound treatment 161680.0 -16800.0 -0.45 218400.0 21400.0 0.58 0.0914 0.1246 3558736 ACon1_000825 CC1CCC2(C)C(CCC=C2C(=O)O)C1(C)CCC3=CC(O)OC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J08 compound treatment 172000.0 -6500.0 -0.17 186960.0 -10100.0 -0.27 -0.3153 -0.9765 3558372 ACon1_000826 CC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]1[C@H]23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J09 compound treatment 168160.0 -10300.0 -0.28 222800.0 25800.0 0.7 0.2982 0.3971 3558673 ACon1_000827 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c3c(=O)cc(oc3c1OC)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J10 compound treatment 175480.0 -3020.0 -0.08 192920.0 -4090.0 -0.11 -0.1354 -0.9879 3553747 ACon1_000828 CC(O)C(C)CC/C=C(\C)/C(O)C/C=C(\C)/C=C/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J11 compound treatment 169080.0 -9420.0 -0.25 194360.0 -2650.0 -0.07 -0.2289 -0.8739 3614508 ACon1_000829 COc1cc(oc(=O)c1C)/C(=C/C(C)CCCC(=O)O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J12 compound treatment 16640.0 -162000.0 -4.33 20400.0 -177000.0 -4.78 -6.4423 -0.9988 3554483 ACon1_000830 CN1C(=O)C23CC4=CC=CC(OC(=O)C)C4N3C(=O)C1(CO)SS2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J13 compound treatment 183200.0 4700.0 0.13 205800.0 8790.0 0.24 0.2572 0.9556 3559771 ACon1_000831 COc1ccc(/C=C/2\Oc3cc(O)cc(O)c3C2=O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J14 compound treatment 190880.0 12400.0 0.33 234920.0 37900.0 1.03 0.9599 0.8901 3557886 ACon1_000832 COc1cc(CCCO)cc2C(CO)C(Oc21)c3ccc(OC)c(OC4OC(CO)C(O)C(O)C4O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J15 compound treatment 175920.0 -2580.0 -0.07 196600.0 -412.0 -0.01 -0.0566 -0.811 3559738 ACon1_000833 COC1=CC(C)c2c(C)c3c(C)coc3c(OC)c2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J16 compound treatment 15560.0 -163000.0 -4.36 20000.0 -177000.0 -4.79 -6.4704 -0.9989 3558192 ACon1_000834 C[C@H]1[C@H]2[C@H](CC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]6O)O[C@@]91CCC(C)CO9 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J17 compound treatment 184480.0 5980.0 0.16 215520.0 18500.0 0.5 0.4675 0.8887 3558487 ACon1_000835 CC1=C2[C@H](O)C(=O)O[C@H](c3ccoc3)[C@]2(C)CC[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J18 compound treatment 163200.0 -15300.0 -0.41 217680.0 20700.0 0.56 0.1063 0.1534 3553097 ACon1_000836 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/[C@H](C/C=C(\C)/C[C@@H]2O)OC(=O)C(=C)[C@@H]3CCC(=C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO[C@H]6OC[C@](O)(CO)[C@H]6O)[C@@H](O)[C@H](O)[C@H]5O)C(=C)[C@@H]4C3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J19 compound treatment 180640.0 2140.0 0.06 220040.0 23000.0 0.62 0.4814 0.7689 3614518 ACon1_000837 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=CC(=O)C(C)(O)C(O)C2CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J20 compound treatment 14360.0 -164000.0 -4.39 16920.0 -180000.0 -4.88 -6.552 -0.9986 3558583 ACon1_000838 C/C=C(/C)\C(=O)OC1C(=C)C2CC31CCC4[C@](C)(CCC[C@]4(C)C3CC2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J21 mock treatment 174560.0 -3940.0 -0.11 205720.0 8710.0 0.24 0.0922 0.3573 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J22 mock treatment 176560.0 -1940.0 -0.05 192080.0 -4930.0 -0.13 -0.131 -0.915 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J23 compound treatment 14280.0 -164000.0 -4.39 14240.0 -183000.0 -4.95 -6.6049 -0.9982 3558317 ACon1_000839 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@H]3CC[C@]4(C)C5CC[C@]6(C)[C@H](CC[C@]6(O)[C@@H]5CCC4=C3)c7ccc(=O)oc7)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 J24 compound treatment 19640.0 -159000.0 -4.25 18600.0 -178000.0 -4.83 -6.42 -0.998 3614523 ACon1_000840 COC1C(=O)Nc2ccc3C=CC(C)(CCC=C(C)C)Oc3c2C1(O)c4ccc(OC)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K01 compound treatment 177160.0 -1340.0 -0.04 226800.0 29800.0 0.81 0.545 0.6751 3558362 ACon1_000841 CC(=CCC/C(=C/C(O)C/C(=C/C(O)CC(C)(O)C=C)/C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K02 compound treatment 216520.0 38000.0 1.02 202160.0 5150.0 0.14 0.8177 0.7966 3558452 ACon1_000842 COc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K03 compound treatment 197480.0 19000.0 0.51 218960.0 21900.0 0.59 0.7792 0.9969 3558557 ACon1_000843 C/C(=C/COc1c(OC2OC(CO)C(O)C(O)C2O)ccc3ccc(=O)oc13)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K04 compound treatment 188800.0 10300.0 0.28 211080.0 14100.0 0.38 0.4642 0.9874 3558485 ACon1_000844 CC1[C@H]2C[C@@H]3[C@@H](CC[C@@]3(C)O)C(=C)CC2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K05 compound treatment 214680.0 36200.0 0.97 231640.0 34600.0 0.94 1.3473 0.9999 3557306 ACon1_000845 CC1=CC2O[C@@H]3[C@H](O)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@](C)(C53CO5)[C@@]2(CO)CC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K06 compound treatment 173600.0 -4900.0 -0.13 191960.0 -5050.0 -0.14 -0.1893 -0.9998 3614529 ACon1_000846 COc1ccc2C(=O)[C@]3(O)[C@@H](COc4cc5OCOc5cc43)Oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K07 mock treatment 186000.0 7500.0 0.2 192760.0 -4250.0 -0.12 0.0605 0.2616 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K08 mock treatment 172400.0 -6100.0 -0.16 207120.0 10100.0 0.27 0.0782 0.2455 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K09 compound treatment 191960.0 13500.0 0.36 236800.0 39800.0 1.08 1.0163 0.8948 3558035 ACon1_000847 CC1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C(CO)C(O)CC31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K10 compound treatment 14120.0 -164000.0 -4.4 18640.0 -178000.0 -4.83 -6.5237 -0.9989 3554481 ACon1_000848 CN1C(=O)[C@@]2(Cc3ccccc3)SSS[C@]1(CO)C(=O)N2C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K11 compound treatment 65800.0 -113000.0 -3.01 106560.0 -90500.0 -2.45 -3.8631 -0.9947 3614533 ACon1_000849 CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC(O)CC(O)CC(=O)O)C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K12 compound treatment 176240.0 -2260.0 -0.06 233640.0 36600.0 0.99 0.6585 0.6628 3558064 ACon1_000850 COc1cc2oc(cc(=O)c2c(O)c1OC)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K13 compound treatment 170320.0 -8180.0 -0.22 203200.0 6190.0 0.17 -0.0362 -0.1314 3558118 ACon1_000851 COc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(=O)O)cc(O)c3c(=O)cc(oc13)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K14 compound treatment 187520.0 9020.0 0.24 221400.0 24400.0 0.66 0.6375 0.9069 3557898 ACon1_000852 C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K15 mock treatment 162280.0 -16200.0 -0.43 213760.0 16700.0 0.45 0.0139 0.0221 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K16 mock treatment 164560.0 -13900.0 -0.37 200560.0 3550.0 0.1 -0.1957 -0.5083 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K17 compound treatment 168480.0 -10000.0 -0.27 210880.0 13900.0 0.38 0.076 0.1648 3558293 ACon1_000853 CC(C)c1cc2CCC3C(C)(CO)C[C@H](O)C[C@]3(C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K18 compound treatment 168760.0 -9740.0 -0.26 200960.0 3950.0 0.11 -0.1086 -0.3857 3558216 ACon1_000854 CC1=C2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3CC1)C(=CC2=O)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K19 compound treatment 158560.0 -19900.0 -0.53 164800.0 -32200.0 -0.87 -0.9937 -0.9721 3553957 ACon1_000855 CC1C(OC(=O)C)C(OC(=O)C)C2=C(CCCC2(C)C)C1(C)CCC(C)(O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K20 compound treatment 184000.0 5500.0 0.15 201800.0 4790.0 0.13 0.1958 0.998 3558262 ACon1_000856 CC(C)C(O)(C(=O)C)C(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K21 compound treatment 206120.0 27600.0 0.74 197640.0 628.0 0.02 0.5345 0.7232 3558329 ACon1_000857 COc1c(O)cc(CCc2cc(O)cc(O)c2)cc1CC(O)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K22 compound treatment 194800.0 16300.0 0.44 190760.0 -6250.0 -0.17 0.1887 0.4034 3553545 ACon1_000858 CC(C)C(OC(=O)C)c1nc2ccccc2c(=O)n1C3CC4(OC3=O)C5N(O)C(C)(C)C(=O)N5c6ccccc64 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K23 mock treatment 199960.0 21500.0 0.57 200680.0 3670.0 0.1 0.4762 0.8173 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 K24 mock treatment 186080.0 7580.0 0.2 203080.0 6070.0 0.16 0.2596 0.9945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L01 compound treatment 33960.0 -145000.0 -3.87 40320.0 -157000.0 -4.24 -5.7334 -0.9989 3552660 ACon1_000859 C[C@@H]1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C)[C@@](C)(O)C(=O)[C@H]3O[C@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L02 compound treatment 13600.0 -165000.0 -4.41 15280.0 -182000.0 -4.92 -6.5978 -0.9985 3558654 ACon1_000860 COc1cc(/C=C/C(=O)CC(=O)\C=C\c2ccc(O)c(O)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L03 compound treatment 201880.0 23400.0 0.63 216960.0 19900.0 0.54 0.8242 0.9973 3558666 ACon1_000861 C[C@H]1CC[C@@H]2[C@@H](OC(=O)C2=C)C(=C)[C@H]1CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L04 compound treatment 191920.0 13400.0 0.36 252920.0 55900.0 1.51 1.3242 0.8512 3559920 ACon1_000862 CC(=CCc1c(O[C@@H]2O[C@H](COC(=O)CC(=O)O)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)[C@H](O)[C@H](Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L05 compound treatment 217160.0 38700.0 1.03 243760.0 46700.0 1.27 1.6262 0.995 3558706 ACon1_000863 CC1C2C3=CCC4C5(C)C[C@@H](O)[C@H](O)C(C)(CO)C5CCC4(C)C3(C)CCC2(CCC1=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L06 compound treatment 12840.0 -166000.0 -4.43 17240.0 -180000.0 -4.87 -6.5747 -0.9989 3558287 ACon1_000864 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)O[C@@]%111CCC(C)CO%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L07 mock treatment 190080.0 11600.0 0.31 201040.0 4030.0 0.11 0.2962 0.9017 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L08 mock treatment 168320.0 -10200.0 -0.27 214960.0 17900.0 0.49 0.1511 0.2713 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L09 compound treatment 177840.0 -656.0 -0.02 196080.0 -932.0 -0.03 -0.0303 -0.9843 3552042 ACon1_000865 C/C=C(\C)/CC(/C=C(\C)/C(O)C(C)/C=C(\C)/C(O)C(C)/C=C/C(O)C/C=C/C(O)C(O)C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L10 compound treatment 167160.0 -11300.0 -0.3 245040.0 48000.0 1.3 0.705 0.528 3558492 ACon1_000866 COc1cc(CC2COC(C2COC(=O)C)c3ccc(O)c(OC)c3)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L11 compound treatment 28080.0 -150000.0 -4.02 32240.0 -165000.0 -4.46 -5.9993 -0.9987 3614544 ACon1_000867 CC1CCC/C=C/2\C3C(OC(=C3C(=O)O1)\C=C\C=C\C=C\C(=O)O)C=CC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L12 compound treatment 179480.0 984.0 0.03 220800.0 23800.0 0.64 0.474 0.7354 3554712 ACon1_000868 COC(=O)c1cc(OC)cc(O)c1C(=O)c2c(O)cc(C)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L13 compound treatment 215560.0 37100.0 0.99 240960.0 43900.0 1.19 1.5423 0.9959 3559773 ACon1_000869 COc1cc(/C=C/2\Oc3cc(O)cc(O)c3C2=O)cc(OC)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L14 compound treatment 129880.0 -48600.0 -1.3 167880.0 -29100.0 -0.79 -1.4772 -0.9713 3558463 ACon1_000870 CC(C)c1cc2C3OC(=O)[C@@]4(CCCC(C)(C)C4[C@H]3O)c2c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L15 mock treatment 176680.0 -1820.0 -0.05 229480.0 32500.0 0.88 0.5872 0.667 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L16 mock treatment 178840.0 344.0 0.01 210040.0 13000.0 0.35 0.2559 0.7253 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L17 compound treatment 179760.0 1260.0 0.03 210560.0 13500.0 0.37 0.2833 0.769 3555854 ACon1_000871 OC(=O)CCC1OC(=O)C(=C1c2ccccc2)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L18 compound treatment 182560.0 4060.0 0.11 188880.0 -8130.0 -0.22 -0.0788 -0.321 3553101 ACon1_000872 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/[C@H](C/C=C(\C)/C[C@@H]2O)OC(=O)C(=C)[C@@H]3CCC(=C)[C@@H]4C[C@H](O[C@@H]5O[C@H](COC(=O)CC(=O)O)[C@@H](O)[C@H](O)[C@H]5O)C(=C)[C@@H]4C3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L19 compound treatment 216320.0 37800.0 1.01 207440.0 10400.0 0.28 0.915 0.8711 3614554 ACon1_000873 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=C(Cl)C(=O)C(C)(O)C(O)C2=CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L20 compound treatment 13280.0 -165000.0 -4.42 21680.0 -175000.0 -4.75 -6.4814 -0.9994 3558638 ACon1_000874 C/C=C(/C)\C(=O)O[C@H]\1C[C@@H]2[C@H](OC(=O)C2=C)[C@@H]3O[C@]3(C)CC/C=C1\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L21 compound treatment 163360.0 -15100.0 -0.4 187240.0 -9770.0 -0.26 -0.4734 -0.9787 3554505 ACon1_000875 CO[C@@H]1C[C@]2(CC=C)[C@@H](C)[C@@H](OC2=C(OC)C1=O)c3cc4OCOc4c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L22 compound treatment 187440.0 8940.0 0.24 195040.0 -1970.0 -0.05 0.1314 0.5361 3558750 ACon1_000876 CC(=CCCC(=CCCC(=CC1C(O)C=C(C)C1=O)C)C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L23 mock treatment 199920.0 21400.0 0.57 213720.0 16700.0 0.45 0.7251 0.9931 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 L24 mock treatment 180680.0 2180.0 0.06 205840.0 8830.0 0.24 0.2103 0.8548 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M01 compound treatment 180200.0 1700.0 0.05 207960.0 10900.0 0.3 0.2418 0.8064 2112282 ACon1_000877 CC1=C2C(=O)O[C@@H](c3ccoc3)[C@]2(C)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M02 compound treatment 214560.0 36100.0 0.96 218760.0 21700.0 0.59 1.0984 0.972 3558453 ACon1_000878 COc1cc(ccc1O)c2cc(=O)c3c(O)c(OC)c(OC)c(O)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M03 compound treatment 290600.0 112000.0 3.0 195320.0 -1690.0 -0.05 2.088 0.6962 3558587 ACon1_000879 COc1cc(C[C@@H]2COC([C@@H]2CO)c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)ccc1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M04 compound treatment 157840.0 -20700.0 -0.55 229440.0 32400.0 0.88 0.2301 0.2218 3554680 ACon1_000880 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/[C@@H]1CC(=O)OCC(C3CCC(C)C3C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M05 compound treatment 26720.0 -152000.0 -4.06 40760.0 -156000.0 -4.23 -5.8619 -0.9998 3553941 ACon1_000881 CC1=CC2O[C@@H]3[C@H](O)[C@@H](O)[C@@](C)(C43CO4)[C@@]2(CO)CC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M06 compound treatment 47520.0 -131000.0 -3.5 81200.0 -116000.0 -3.14 -4.6943 -0.9985 3559292 ACon1_000882 CO[C@H]1C[C@@H](Oc2c(CC=C(C)C)c(OC)cc(OC)c12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M07 compound treatment 159320.0 -19200.0 -0.51 180280.0 -16700.0 -0.45 -0.683 -0.9981 3557952 ACon1_000883 COc1ccc(C2COc3cc(O)ccc3C2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M08 compound treatment 178360.0 -136.0 0.0 213880.0 16900.0 0.46 0.3203 0.7014 3554197 ACon1_000884 CCC1(C)C(O)C2=COC(=C(C)C2=CC1=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M09 mock treatment 177080.0 -1420.0 -0.04 186200.0 -10800.0 -0.29 -0.2338 -0.792 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M10 mock treatment 158360.0 -20100.0 -0.54 276760.0 79700.0 2.16 1.1458 0.5149 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M11 compound treatment 174920.0 -3580.0 -0.1 208600.0 11600.0 0.31 0.1542 0.4701 3553758 ACon1_000885 CC(O)CCCC1Cc2cccc(O)c2C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M12 compound treatment 185880.0 7380.0 0.2 228080.0 31100.0 0.84 0.7344 0.85 3554988 ACon1_000886 COc1cc(O)c2c(=O)oc3c(O)c(OC)cc(C)c3c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M13 mock treatment 160880.0 -17600.0 -0.47 209560.0 12500.0 0.34 -0.093 -0.1601 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M14 mock treatment 184440.0 5940.0 0.16 239120.0 42100.0 1.14 0.9185 0.798 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M15 compound treatment 198240.0 19700.0 0.53 223600.0 26600.0 0.72 0.8824 0.9884 3614568 ACon1_000887 CC1OC(OC(=O)C2=CC3CC(C)(C)CC34C2CC(=O)OC4C)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M16 compound treatment 180040.0 1540.0 0.04 251200.0 54200.0 1.47 1.0665 0.7267 3557904 ACon1_000888 Cc1c(O[C@@H]2O[C@H](COC(=O)CC(C)(O)CC(=O)O)C[C@H](O)[C@H]2O)occc1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M17 compound treatment 362600.0 184000.0 4.92 185720.0 -11300.0 -0.31 3.266 0.6619 3554555 ACon1_000889 COC(=O)[C@]1(C)CCC[C@@]2(C)C1CC(OC(=O)C)C3=C2CC(OC(=O)C)[C@](C)(C=C)C3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M18 compound treatment 112280.0 -66200.0 -1.77 170640.0 -26400.0 -0.71 -1.7573 -0.9202 3557955 ACon1_000890 CC(O)CCCCCCCCCC(Cc1cc(O)cc(O)c1)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M19 compound treatment 173400.0 -5100.0 -0.14 206800.0 9790.0 0.26 0.091 0.3053 3558411 ACon1_000891 C[C@]1(O)CC[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](COC(=O)c4ccc(O)cc4)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M20 compound treatment 165640.0 -12900.0 -0.34 187160.0 -9850.0 -0.27 -0.4318 -0.9921 3554267 ACon1_000892 CCCCCC(O)C1OC(=O)CCC(O)C(O)/C=C/C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M21 compound treatment 176480.0 -2020.0 -0.05 191960.0 -5050.0 -0.14 -0.1348 -0.9172 3558351 ACon1_000893 Cc1cc(O)c2C(=O)c3c(O)cc(OC4OC(COC(=O)CC(=O)O)C(O)C(O)C4O)cc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M22 compound treatment 188880.0 10400.0 0.28 200040.0 3030.0 0.08 0.2544 0.8783 3552748 ACon1_000894 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(=O)C)[C@H](O[C@@H]3[C@@H](O)[C@H](C)O[C@@H](Oc4ccc5c(=O)c(coc5c4)c6ccc(O)cc6)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M23 compound treatment 178800.0 304.0 0.01 201720.0 4710.0 0.13 0.0959 0.7507 3558422 ACon1_000895 CC(=O)OC1C(=C)C2C[C@]31CCC4[C@@](C)(CCC[C@@]4(C)C3CC2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 M24 compound treatment 195400.0 16900.0 0.45 187960.0 -9050.0 -0.25 0.1464 0.2847 3558504 ACon1_000896 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H]3[C@@H](C[C@H](O)C3=C)C(=C)C[C@@H]2O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N01 compound treatment 186920.0 8420.0 0.23 198800.0 1790.0 0.05 0.1936 0.8398 3555900 ACon1_000897 OC[C@H]1O[C@@H](Oc2cc(O)cc3oc(=O)cc(c4ccc(O)c(O)c4)c23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N02 compound treatment 202120.0 23600.0 0.63 203240.0 6230.0 0.17 0.566 0.8655 3614577 ACon1_000898 CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(OC6OCC(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1O)C(=O)OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N03 compound treatment 173720.0 -4780.0 -0.13 204480.0 7470.0 0.2 0.0526 0.22 3558675 ACon1_000899 COc1ccccc1c2cc(=O)c3c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(OC)c(OC)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N04 compound treatment 175200.0 -3300.0 -0.09 230840.0 33800.0 0.92 0.5852 0.6361 3559922 ACon1_000900 CC(=CCc1c(O[C@@H]2O[C@H](COC(=O)CC(=O)O)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)C[C@H](Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N05 compound treatment 196120.0 17600.0 0.47 211600.0 14600.0 0.39 0.6126 0.9961 3614580 ACon1_000901 CC1=CCC2C(C)(CO)CCCC2(C)C1CC34OC4C(O)C(=CC3O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N06 compound treatment 12120.0 -166000.0 -4.45 16040.0 -181000.0 -4.9 -6.6113 -0.9988 3558417 ACon1_000902 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](OC(=O)C)[C@@H]2OC(=O)\C=C\c7ccc(OC)cc7)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N07 compound treatment 165800.0 -12700.0 -0.34 188880.0 -8130.0 -0.22 -0.3958 -0.978 3557311 ACon1_000903 CC(C)CCC(O)C1CC(CO)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N08 compound treatment 157800.0 -20700.0 -0.55 201320.0 4310.0 0.12 -0.309 -0.5462 3558683 ACon1_000904 CC(C)(O)CCC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(CC(OC5OC(CO)C(O)C(O)C5O)C(O)C4(C)C)C3(C)CCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N09 mock treatment 166680.0 -11800.0 -0.32 204640.0 7630.0 0.21 -0.0775 -0.2052 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N10 mock treatment 167720.0 -10800.0 -0.29 213840.0 16800.0 0.46 0.1183 0.2195 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N11 compound treatment 182680.0 4180.0 0.11 223760.0 26700.0 0.72 0.5912 0.8068 3614587 ACon1_000905 CC1CCC/C=C/C/C=C\C(OC(=O)/C=C\C=C\C=C\C(=O)O)/C=C/C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N12 compound treatment 192040.0 13500.0 0.36 229200.0 32200.0 0.87 0.8723 0.9244 3558740 ACon1_000906 COc1ccc(cc1)c2oc3cc(OC)cc(O)c3c(=O)c2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N13 mock treatment 162240.0 -16300.0 -0.43 197520.0 508.0 0.01 -0.2978 -0.6844 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N14 mock treatment 196360.0 17900.0 0.48 212600.0 15600.0 0.42 0.6363 0.9981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N15 compound treatment 152960.0 -25500.0 -0.68 205920.0 8910.0 0.24 -0.3125 -0.4314 3559368 ACon1_000907 CC(=C)C1CCC2(CCC3(C)C(CCC4C5(C)C(C=O)C(O)C(C)(CO)C5CCC43C)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N16 compound treatment 16360.0 -162000.0 -4.34 28040.0 -169000.0 -4.57 -6.3013 -0.9996 3552752 ACon1_000908 C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C)C4C[C@@H](O)[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CCC3=C2)c6ccc(=O)oc6)[C@H](O)[C@H](O)[C@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N17 compound treatment 162880.0 -15600.0 -0.42 212280.0 15300.0 0.41 -0.0031 -0.0053 3553640 ACon1_000909 CC(C)Cc1cnc(CCC(=O)N)c(=O)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N18 compound treatment 155320.0 -23200.0 -0.62 211840.0 14800.0 0.4 -0.1545 -0.2092 3558595 ACon1_000910 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O[C@H]7OC[C@](O)(CO)[C@H]7O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N19 compound treatment 159160.0 -19300.0 -0.52 176040.0 -21000.0 -0.57 -0.7672 -0.9989 3614597 ACon1_000911 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=C(Cl)C(=O)C(C)(O)C(OC(=O)C)C2CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N20 compound treatment 61000.0 -117000.0 -3.14 87360.0 -110000.0 -2.97 -4.3214 -0.9996 3558712 ACon1_000912 CC(C)C(=O)OC/C(=C/CCC(=C)C1CC=C(COC(=O)C(C)C)C(O)C1)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N21 compound treatment 167920.0 -10600.0 -0.28 190560.0 -6450.0 -0.17 -0.3236 -0.9731 3614600 ACon1_000913 CC(CCO)/C=C(\C)/C=C/C1=CC2=CC(=O)C(C)(O)C(O)C2=CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N22 compound treatment 14120.0 -164000.0 -4.4 20280.0 -177000.0 -4.78 -6.4923 -0.9991 3559260 ACon1_000914 CC1OC(OC2C(O)C(CO)OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)OC8OCC(OC9OCC(O)C(O)C9O)C(O)C8O)C3(C)C)C2O)C(O)C(OC%10OCC(O)(CO)C%10O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N23 compound treatment 190720.0 12200.0 0.33 173880.0 -23100.0 -0.63 -0.2116 -0.2995 3558089 ACon1_000915 COC1CC(O[C@H]2CC[C@]3(C)C4[C@H](O)[C@@H](O)[C@]5(C)[C@H](CC[C@]5(O)C4CC=C3C2)[C@H](C)O)OC(C)C1OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 N24 compound treatment 214480.0 36000.0 0.96 210040.0 13000.0 0.35 0.93 0.9072 3557301 ACon1_000916 CC(OC(=O)c1cccc(O)c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O01 compound treatment 203960.0 25500.0 0.68 236400.0 39400.0 1.07 1.2356 0.9766 3557296 ACon1_000917 C[C@@H]1Cc2c(O)c(O)cc(O)c2C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O02 compound treatment 129400.0 -49100.0 -1.31 197680.0 668.0 0.02 -0.9158 -0.6973 3497202 ACon1_000918 CC(=CCO)CCC1C(C)(O)CCC2C(C)(C)CCCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O03 compound treatment 185920.0 7420.0 0.2 195400.0 -1610.0 -0.04 0.1096 0.5388 3558589 ACon1_000919 CSC(=O)OCC1=C[C@H](O)[C@H]2[C@@H]1[C@H](OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O04 compound treatment 191040.0 12500.0 0.34 230080.0 33100.0 0.9 0.8703 0.9103 3558219 ACon1_000920 C[C@@H]1CC[C@]2(C)[C@H](CC[C@@H](O)[C@]2(C)O)[C@@]1(C)CC/C(=C/CO)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O05 compound treatment 164920.0 -13600.0 -0.36 253960.0 56900.0 1.54 0.8334 0.5262 1045397 ACon1_000921 COc1ccc(cc1OC)c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O06 compound treatment 137560.0 -40900.0 -1.09 147880.0 -49100.0 -1.33 -1.7148 -0.9953 1046376 ACon1_000922 COc1c(O)c2c(=O)cc(oc2c(OC)c1OC)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O07 compound treatment 164120.0 -14400.0 -0.38 240480.0 43500.0 1.18 0.5602 0.4525 3557981 ACon1_000923 OC[C@H]1O[C@@H](OC2OC=C(C3CCC(=C)C32)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O08 compound treatment 153960.0 -24500.0 -0.66 217960.0 20900.0 0.57 -0.0631 -0.0727 3554706 ACon1_000924 COC(=O)c1cc(O)cc(OC)c1C(=O)c2c(O)cc(C)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O09 compound treatment 128800.0 -49700.0 -1.33 232280.0 35300.0 0.95 -0.2648 -0.1618 3551984 ACon1_000925 C/C(=C\OC(=O)/C=C/c1ccc(O)cc1)/C(O)C2OC(=O)/C(=C\COC3OC(CO)C(O)C(O)C3O)/C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O10 compound treatment 123280.0 -55200.0 -1.48 194440.0 -2570.0 -0.07 -1.0936 -0.7396 3558809 ACon1_000926 CC(C)(O)[C@@H]1Cc2cc3cc(c(=O)oc3cc2O1)C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O11 mock treatment 195640.0 17100.0 0.46 225920.0 28900.0 0.78 0.8777 0.9676 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O12 mock treatment 161280.0 -17200.0 -0.46 224920.0 27900.0 0.76 0.2086 0.2358 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O13 compound treatment 185240.0 6740.0 0.18 204560.0 7550.0 0.2 0.272 0.9981 3553125 ACon1_000927 C[C@H]1CC(O)C23COC(=O)[C@@H]3CCC[C@@H]2[C@]41C[C@H](OC4=O)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O14 compound treatment 179120.0 624.0 0.02 234720.0 37700.0 1.02 0.7336 0.7186 3557917 ACon1_000928 C[C@]1(C[C@]2(O)O[C@@H]3O1)[C@]4(C[C@@H]2C34COC(=O)c5ccccc5)O[C@@H]6O[C@H](COC(=O)c7ccccc7)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O15 compound treatment 189360.0 10900.0 0.29 264360.0 67300.0 1.82 1.4947 0.8096 3555917 ACon1_000929 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3oc4c(O)c(O)ccc4c(=O)c3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O16 compound treatment 219840.0 41300.0 1.11 265920.0 68900.0 1.87 2.1011 0.9688 3557831 ACon1_000930 CC1OC(OC2C(O)C(O)C(Oc3cc(O)c4c(=O)c(coc4c3)c5ccc(O)c(O)c5)OC2CO)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O17 compound treatment 192240.0 13700.0 0.37 230240.0 33200.0 0.9 0.896 0.9221 3557287 ACon1_000931 CCCC1CCC(C(=C)C(=O)O)C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O18 compound treatment 143400.0 -35100.0 -0.94 225320.0 28300.0 0.77 -0.1219 -0.1006 3558352 ACon1_000932 C[C@]12C[C@H](OC(=O)C(=C)C(O)CO)[C@@H]3[C@H](OC(=O)C3=C)C2C(CC[C@H]1O)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O19 compound treatment 188440.0 9940.0 0.27 298880.0 102000.0 2.76 2.1382 0.7717 1062453 ACon1_000933 COc1c(O)cc2oc(cc(=O)c2c1O)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O20 compound treatment 190800.0 12300.0 0.33 210840.0 13800.0 0.37 0.4974 0.9979 3557279 ACon1_000934 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3cc(OC)cc(OC)c3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O21 compound treatment 218480.0 40000.0 1.07 200280.0 3270.0 0.09 0.8188 0.763 3558330 ACon1_000935 CC(C)(O)C1Cc2cc(CCc3cc(O)cc(O)c3)ccc2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O22 compound treatment 170440.0 -8060.0 -0.22 222520.0 25500.0 0.69 0.3359 0.4644 3553357 ACon1_000936 CC(=O)OC/C/1=C/CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O23 compound treatment 200480.0 22000.0 0.59 231640.0 34600.0 0.94 1.0787 0.9748 3558425 ACon1_000937 COc1cc(/C=C/C(=O)OCc2ccccc2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 O24 compound treatment 193640.0 15100.0 0.41 226160.0 29100.0 0.79 0.8444 0.952 3555971 ACon1_000938 OCCC(CO)c1c(O)cc2C(=O)c3cc(O)cc(O)c3C(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P01 compound treatment 7720.0 -171000.0 -4.57 8200.0 -189000.0 -5.11 -6.8446 -0.9984 3558656 ACon1_000939 C[C@@H]/1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C)[C@@](C)(O)C(=O)/C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P02 compound treatment 225960.0 47500.0 1.27 205600.0 8590.0 0.23 1.0621 0.8229 3558684 ACon1_000940 CC(=O)OC1CC2(C)C3CC=C4C(CC(OC5OC(CO)C(O)C(O)C5O)C(O)C4(C)C)C3(C)CCC2(C)C1C(C)(O)C(=O)CCC(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P03 compound treatment 186240.0 7740.0 0.21 215280.0 18300.0 0.49 0.4962 0.9254 3558685 ACon1_000941 CC(=O)OC1CC2(C)C3CC=C4C(CC(O)C(O)C4(C)C)C3(C)CCC2(C)C1C(C)(O)C(=O)CCC(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P04 compound treatment 185200.0 6700.0 0.18 203320.0 6310.0 0.17 0.2476 0.9997 3554701 ACon1_000942 COC(=O)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P05 compound treatment 183160.0 4660.0 0.12 226400.0 29400.0 0.8 0.6508 0.8081 3614622 ACon1_000943 CC1=CCC2C(C)(CCCC2(C)C1CC34OC4C(O)C(=C)C(O)C3O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P06 compound treatment 176520.0 -1980.0 -0.05 217560.0 20500.0 0.56 0.356 0.637 3558470 ACon1_000944 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@](C)(C5CC[C@]43C)C(=O)O)C2C1)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P07 compound treatment 37480.0 -141000.0 -3.77 52440.0 -145000.0 -3.91 -5.4348 -0.9998 3553189 ACon1_000945 CC(=CCC/C(=C\CC\C(=C\CC\C(=C\CO)\CO)\C)/C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P08 compound treatment 6240.0 -172000.0 -4.61 9280.0 -188000.0 -5.08 -6.8519 -0.9988 3554753 ACon1_000946 COc1c(C)cc(C(=O)/C=C/c2ccccc2)c(O)c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P09 compound treatment 8280.0 -170000.0 -4.55 13200.0 -184000.0 -4.98 -6.7383 -0.999 3552709 ACon1_000947 C[C@@H]1CCC(=O)[C@H](C)[C@@]1(C)/C=C/C(=C/Cc2c(O)c(Cl)c(C)c(C=O)c2O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P10 compound treatment 166040.0 -12500.0 -0.33 214000.0 17000.0 0.46 0.0896 0.1578 3558180 ACon1_000948 COc1cc(CCCO)cc2[C@@H](CO)[C@@H](Oc21)c3ccc(OC)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P11 mock treatment 176840.0 -1660.0 -0.04 249640.0 52600.0 1.42 0.9761 0.6848 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P12 mock treatment 192920.0 14400.0 0.39 236840.0 39800.0 1.08 1.0352 0.904 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P13 compound treatment 180000.0 1500.0 0.04 223640.0 26600.0 0.72 0.5382 0.7454 3553333 ACon1_000949 CC(=O)O[C@@H]1C[C@](C)(C=C)C=C2[C@H](O)CC3C(C)(C)CC[C@@H](OC(=O)C)[C@]3(C)C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P14 compound treatment 202160.0 23700.0 0.63 268200.0 71200.0 1.93 1.8103 0.8924 3558552 ACon1_000950 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P15 compound treatment 166040.0 -12500.0 -0.33 243200.0 46200.0 1.25 0.6486 0.5012 3559386 ACon1_000951 CC(C)C(O)CC(C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P16 compound treatment 175240.0 -3260.0 -0.09 208160.0 11100.0 0.3 0.1518 0.4833 3558472 ACon1_000952 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@](C)(C5CC[C@]43C)C(=O)O)C2C1)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P17 compound treatment 178880.0 384.0 0.01 248240.0 51200.0 1.39 0.9879 0.7123 3558567 ACon1_000953 CC1=C(CCC2=CC(=O)OC2O)[C@@]3(C)CCC[C@@]4(C)[C@@H]3C(OC4=O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P18 compound treatment 176800.0 -1700.0 -0.05 216840.0 19800.0 0.54 0.3475 0.645 3558599 ACon1_000954 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)OC6OCC(O[C@H]7OC[C@](O)(CO)[C@H]7O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P19 compound treatment 194400.0 15900.0 0.43 226760.0 29700.0 0.81 0.8703 0.9555 3614634 ACon1_000955 CC(C)C1NC(=O)C(CC2(O)C3NC(Cc4ccccc4)C(=O)N3c5ccccc52)NC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P20 compound treatment 10000.0 -168000.0 -4.51 21560.0 -175000.0 -4.75 -6.5457 -0.9997 3551644 ACon1_000956 CC1Oc2c3C=CC(C)(C)Oc3c4c(cc(=O)oc4c2C(=O)C1C)c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P21 compound treatment 187440.0 8940.0 0.24 222280.0 25300.0 0.68 0.6529 0.9009 3554485 ACon1_000957 CN1C(=O)c2ccccc2NC(=O)[C@@]31O[C@@H]3c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P22 compound treatment 191840.0 13300.0 0.36 203360.0 6350.0 0.17 0.3739 0.9439 3554963 ACon1_000958 COc1cc(O)c(C(=O)O)c(c1)c2c(C)cc(oc2=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P23 compound treatment 126120.0 -52400.0 -1.4 141560.0 -55500.0 -1.5 -2.0522 -0.9994 3558309 ACon1_000959 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2292 P24 compound treatment 194160.0 15700.0 0.42 195440.0 -1570.0 -0.04 0.2662 0.632 3557994 ACon1_000960 C[C@@H]1C[C@H](OC(=O)c2ccccc2)[C@H](OC(=O)C)[C@@]3(COC(=O)C)[C@H](C[C@@H]4[C@@H](OC(=O)c5ccccc5)[C@]13OC4(C)C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A01 compound treatment 9720.0 -185000.0 -4.94 9160.0 -190000.0 -5.14 -7.1253 -0.9998 3554483 ACon1_000961 CN1C(=O)C23CC4=CC=CC(OC(=O)C)C4N3C(=O)C1(CO)SS2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A02 compound treatment 260680.0 66300.0 1.77 242120.0 43200.0 1.17 2.081 0.9797 3554004 ACon1_000962 CC1CC23OC3(/C=C(/C)\C(O)C(O)C4C(C(O)C(C)C2=O)C4(C)C)C1OC5OC(CO)C(O)C(O)C5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A03 compound treatment 207040.0 12600.0 0.34 207680.0 8780.0 0.24 0.4071 0.9852 3614644 ACon1_000963 CC(C)CC1NC(=O)C23C1C(=CC(O)C3/C=C/CCC4OC4(C)C(O)CC2=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A04 compound treatment 222720.0 28300.0 0.76 225160.0 26300.0 0.71 1.0383 0.9995 3558783 ACon1_000964 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A05 compound treatment 209280.0 14900.0 0.4 222280.0 23400.0 0.63 0.729 0.975 3553738 ACon1_000965 CC(O)(CC[C@H]1C(=C)CCC2[C@@](C)(CCC[C@]12C)C(=O)O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A06 compound treatment 11960.0 -182000.0 -4.88 12560.0 -186000.0 -5.04 -7.0179 -0.9999 3558578 ACon1_000966 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A07 compound treatment 23040.0 -171000.0 -4.58 25920.0 -173000.0 -4.68 -6.5526 -0.9999 3558828 ACon1_000967 C/C/1=C\CCC2=CC(OC2=O)C(C)(C)/C=C\C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A08 compound treatment 24840.0 -170000.0 -4.54 23800.0 -175000.0 -4.74 -6.5591 -0.9998 3554998 ACon1_000968 COC1CC(O[C@H]2CC[C@@]3(C)[C@H](CCC45OC56CC=C(C7=CC(=O)OC7)[C@@]6(C)CCC43)C2)OC(C)C1O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A09 compound treatment 220600.0 26200.0 0.7 192280.0 -6620.0 -0.18 0.3688 0.5099 3558621 ACon1_000969 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(OC)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A10 compound treatment 29520.0 -165000.0 -4.41 34640.0 -164000.0 -4.45 -6.2631 -1.0 3558846 ACon1_000970 C/C(=C\CC[C@H](CO)[C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]4(C)CCC(=O)C(C)(C)C4CC3)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A11 compound treatment 224480.0 30100.0 0.8 231120.0 32200.0 0.87 1.1857 0.9992 3614654 ACon1_000971 CC(O)CC(=O)c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A12 compound treatment 224520.0 30100.0 0.81 203480.0 4580.0 0.12 0.6573 0.8064 3553484 ACon1_000972 CC(C)(OO)C1=C[C@]23CCC4[C@@](C)(CCC[C@]4(C)C3C[C@@H]1OO2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A13 mock treatment 239040.0 44600.0 1.19 203120.0 4220.0 0.11 0.9251 0.7712 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A14 mock treatment 260160.0 65800.0 1.76 212960.0 14100.0 0.38 1.5129 0.8407 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A15 compound treatment 223440.0 29000.0 0.78 196280.0 -2620.0 -0.07 0.4991 0.6399 3558823 ACon1_000973 CC1CCC2C1C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)OC4C5OC5(C)C6C(OC7OC(CO)C(O)C(O)C7O)OC=CC46O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A16 compound treatment 228440.0 34000.0 0.91 221400.0 22500.0 0.61 1.0745 0.9809 3558930 ACon1_000974 OC1CCC(O)C(O)(C1O)C(=O)OCc2cc(O)ccc2OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A17 compound treatment 228160.0 33800.0 0.9 214720.0 15800.0 0.43 0.9413 0.9419 3558444 ACon1_000975 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A18 compound treatment 32600.0 -162000.0 -4.33 34320.0 -165000.0 -4.46 -6.211 -0.9999 3558953 ACon1_000976 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A19 compound treatment 270520.0 76100.0 2.04 249520.0 50600.0 1.37 2.4087 0.9814 1113957 ACon1_000977 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A20 compound treatment 232840.0 38400.0 1.03 199960.0 1060.0 0.03 0.7473 0.7266 3558990 ACon1_000978 CCCCCC(CC(=O)CCc1ccc(O)c(OC)c1)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A21 compound treatment 10600.0 -184000.0 -4.92 9320.0 -190000.0 -5.13 -7.1056 -0.9998 3558623 ACon1_000979 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A22 compound treatment 9360.0 -185000.0 -4.95 8880.0 -190000.0 -5.14 -7.1375 -0.9998 3558955 ACon1_000980 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A23 compound treatment 213440.0 19000.0 0.51 204120.0 5220.0 0.14 0.46 0.8705 3554993 ACon1_000981 COc1cc(O)cc(c1)C2=C(C)CC(O)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 A24 compound treatment 235760.0 41400.0 1.11 227080.0 28200.0 0.76 1.3217 0.9835 3552069 ACon1_000982 C/C=C/C=C/C(=O)C1=C(O)[C@]2(C)C3C(=C(O)C4(C)C1[C@]5(C)O[C@@]4(O)[C@@]3(C)O[C@@]52O)C(=O)\C=C\C=C\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B01 compound treatment 280560.0 86200.0 2.3 235880.0 37000.0 1.0 2.3375 0.9303 3558240 ACon1_000983 C[C@@H]1O[C@@H](Oc2ccc3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B02 compound treatment 232120.0 37700.0 1.01 239080.0 40200.0 1.09 1.4826 0.9993 3554879 ACon1_000984 COc1cc(ccc1O)C2C(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(CO)Cc4cc(OC)c(O)cc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B03 compound treatment 267400.0 73000.0 1.95 256240.0 57300.0 1.55 2.4784 0.9935 3559896 ACon1_000985 COc1ccc(cc1OC)c2oc3cc(OC)c(OC)c(O)c3c(=O)c2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B04 compound treatment 209440.0 15000.0 0.4 203720.0 4820.0 0.13 0.3767 0.8908 2060503 ACon1_000986 C1Oc2ccc(cc2O1)[C@H]3OC[C@@H]4[C@@H](OC[C@H]34)c5ccc6OCOc6c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B05 compound treatment 213160.0 18800.0 0.5 223000.0 24100.0 0.65 0.8161 0.9916 3557603 ACon1_000987 CC1(CCCC2(C)C3CCC4CC3(CC4(O)CO)CCC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B06 compound treatment 269360.0 75000.0 2.01 283160.0 84300.0 2.28 3.0308 0.9979 3559134 ACon1_000988 Oc1ccc(cc1O)C2CC(=O)c3ccc(O)c(O)c3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B07 compound treatment 205280.0 10900.0 0.29 233480.0 34600.0 0.94 0.8677 0.8851 3558984 ACon1_000989 C/C(=C\CCC1(C)C2CC3C(C2)C31C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B08 compound treatment 213160.0 18800.0 0.5 222480.0 23600.0 0.64 0.8062 0.9929 3559662 ACon1_000990 COC1=CC(=O)O[C@@H](CCc2ccccc2)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B09 compound treatment 18000.0 -176000.0 -4.72 18120.0 -181000.0 -4.89 -6.7972 -0.9998 3554161 ACon1_000991 CCC(C)CC(C)/C=C(\C)/[C@H]1OC2=C([C@@H](O)[C@@H]1O)C(=C)N(OC)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B10 compound treatment 222680.0 28300.0 0.76 246360.0 47500.0 1.28 1.4434 0.9681 3558358 ACon1_000992 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)OC(=O)/C=C/c5ccc(O)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B11 compound treatment 196560.0 2160.0 0.06 214240.0 15300.0 0.42 0.3345 0.7977 3558976 ACon1_000993 COc1ccc(cc1)C2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B12 compound treatment 222440.0 28000.0 0.75 222160.0 23300.0 0.63 0.9756 0.9962 2102488 ACon1_000994 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B13 mock treatment 208320.0 13900.0 0.37 187600.0 -11300.0 -0.31 0.0469 0.0974 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B14 mock treatment 207440.0 13000.0 0.35 224400.0 25500.0 0.69 0.7347 0.95 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B15 compound treatment 18720.0 -176000.0 -4.7 17640.0 -181000.0 -4.91 -6.7928 -0.9998 3559076 ACon1_000995 CC1C2C(CC3C4CC=C5C[C@@H](O)CC(O)[C@]5(C)C4CC[C@]23C)OC61CCC(C)CO6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B16 compound treatment 223400.0 29000.0 0.78 202200.0 3300.0 0.09 0.6116 0.7834 3558644 ACon1_000996 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c3c(cc(=O)oc3c1)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B17 compound treatment 200360.0 5960.0 0.16 187000.0 -11900.0 -0.32 -0.1151 -0.3203 3559113 ACon1_000997 Cc1c(O)c(C)c2oc(cc(=O)c2c1O)c3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B18 compound treatment 233200.0 38800.0 1.04 190040.0 -8860.0 -0.24 0.5642 0.5297 3559079 ACon1_000998 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3ccc(C=C)cc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B19 compound treatment 186000.0 -8400.0 -0.22 193840.0 -5060.0 -0.14 -0.2558 -0.9718 3558382 ACon1_000999 C[C@@H]1OC(O[C@H]2[C@H](O)[C@@H](COC(=O)/C=C/c3ccc(O)c(O)c3)O[C@@H](OCCc4ccc(O)c(O)c4)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B20 compound treatment 205240.0 10800.0 0.29 190160.0 -8740.0 -0.24 0.0377 0.1007 3559123 ACon1_001000 O[C@@]12CO[C@@H]([C@H]2CO[C@@H]1c3ccc4OCOc4c3)c5ccc6OCOc6c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B21 compound treatment 12880.0 -182000.0 -4.86 11880.0 -187000.0 -5.06 -7.0135 -0.9998 3559488 ACon1_001001 C/C=C(\COC(=O)C)/C(=O)O[C@@H]1CC2(C)OC(=CC2=O)\C(=C/[C@@H]3OC(=O)C(=C)C31)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B22 compound treatment 224200.0 29800.0 0.8 227400.0 28500.0 0.77 1.1092 0.9999 3553151 ACon1_001002 C[C@H]1CCCC2=CC[C@H](C[C@]12C)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B23 compound treatment 214520.0 20100.0 0.54 190320.0 -8580.0 -0.23 0.2163 0.369 3552728 ACon1_001003 C[C@@H]1CCC2C(C)(C)CCC[C@@]2(C)[C@@]1(O)CCC(=CCO)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 B24 compound treatment 35080.0 -159000.0 -4.26 34600.0 -164000.0 -4.45 -6.1587 -0.9998 329 ACon1_001004 CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C01 compound treatment 242160.0 47800.0 1.28 226280.0 27400.0 0.74 1.4274 0.9665 3614681 ACon1_001005 CO[C@H]1C(=O)Nc2ccc(/C=C/C(=C)C)c(O)c2[C@]1(O)c3ccc(OC)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C02 compound treatment 211480.0 17100.0 0.46 203520.0 4620.0 0.13 0.4115 0.8688 3558734 ACon1_001006 CC1(C)C2CC[C@]3(CC4CC[C@H]3[C@]2(C)CCC1=O)C[C@@]4(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C03 compound treatment 215960.0 21600.0 0.58 194120.0 -4780.0 -0.13 0.3162 0.5351 3553883 ACon1_001007 CC1(C)Oc2c(CCO)c3occ(c4ccc(O)c(O)c4)c(=O)c3c(O)c2C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C04 compound treatment 196520.0 2120.0 0.06 203920.0 5020.0 0.14 0.1362 0.9247 3555922 ACon1_001008 OC1C(O)C(COC(=O)CC2(O)C=CC(=O)C=C2)OC(OC(=O)CC3(O)C=CC(=O)C=C3)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C05 compound treatment 201280.0 6880.0 0.18 216760.0 17900.0 0.48 0.472 0.9123 3552112 ACon1_001009 C/C=C\1/[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)OC=C3[C@H]1CC(=O)OC[C@@H]4[C@@H](C)[C@@H](C[C@H]4C(C)CO)OC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C06 compound treatment 207080.0 12700.0 0.34 192440.0 -6460.0 -0.17 0.1161 0.3044 3558787 ACon1_001010 C[C@@H]1O[C@@H](OCC2OC(OC3C(O)C(O)C(CO)OC3OC4C(O)C(O)C(CO)OC4Oc5c(oc6cc(O)cc(O)c6c5=O)c7ccc(O)c(O)c7)C(O)C(O)C2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C07 compound treatment 206520.0 12100.0 0.32 207200.0 8300.0 0.22 0.3881 0.984 3558850 ACon1_001011 C[C@@H]1C(=O)[C@@H](O)[C@]2(COC(=O)C)[C@H](CCC[C@@]32CO3)[C@]41CC(OC4OC(=O)C)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C08 compound treatment 210600.0 16200.0 0.43 213960.0 15100.0 0.41 0.5947 0.9995 3558834 ACon1_001012 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C09 compound treatment 216280.0 21900.0 0.59 181760.0 -17100.0 -0.46 0.0857 0.1147 3554277 ACon1_001013 CCCCCC1CC(O)C(O)C(CC(=O)OC(CCC)CCCC(CC(=O)O1)OC2OC(CO)C(O)C(O)C2NC(=O)C)OC(=O)CC(C)(O)CC(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C10 compound treatment 217320.0 22900.0 0.61 202440.0 3540.0 0.1 0.5012 0.8078 3558858 ACon1_001014 CC1OC(OC2C(O)C(C)OC(OCC3OC(OC4C(C)OC(Oc5cc(O)c6c(=O)c(O)c(oc6c5)c7ccc(O)c(O)c7)C(O)C4O)C(O)C(O)C3OC(=O)/C=C/c8ccc(O)cc8)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C11 mock treatment 202440.0 8040.0 0.21 206640.0 7740.0 0.21 0.3002 0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C12 mock treatment 194320.0 -82.7 0.0 194840.0 -4060.0 -0.11 -0.0793 -0.7212 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C13 compound treatment 173680.0 -20700.0 -0.55 171720.0 -27200.0 -0.74 -0.9123 -0.9902 3558742 ACon1_001015 CC1=CCC2[C@](C)(CCC[C@]2(C)[C@H]1CCc3ccoc3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C14 compound treatment 238400.0 44000.0 1.18 226240.0 27300.0 0.74 1.3556 0.975 3558795 ACon1_001016 CC(O)(CC(=O)O)CC(=O)OCC1OC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C15 mock treatment 191240.0 -3160.0 -0.08 185440.0 -13500.0 -0.36 -0.3175 -0.8487 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C16 mock treatment 217960.0 23600.0 0.63 199680.0 780.0 0.02 0.4605 0.7304 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C17 compound treatment 193480.0 -923.0 -0.02 190760.0 -8140.0 -0.22 -0.1733 -0.7814 3558891 ACon1_001017 CCCC1CCCCCCCCCC(=O)OC2C(OC3OC(CO)C(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4OC(=O)C(C)CC)C(O)C3O)C(O)C(C)OC2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C18 compound treatment 18600.0 -176000.0 -4.7 17520.0 -181000.0 -4.91 -6.7974 -0.9998 3558933 ACon1_001018 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O[C@@H]3OC[C@H](O)[C@H](O)[C@H]3O)O[C@H]1O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)CC[C@@]8(CC[C@]76C)C(=O)O)C4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C19 compound treatment 207160.0 12800.0 0.34 187480.0 -11400.0 -0.31 0.0227 0.0493 3614691 ACon1_001019 CC1CC(=O)c2c(C1)ccc3C(=O)c4cccc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)c4C(=O)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C20 compound treatment 206120.0 11700.0 0.31 188160.0 -10700.0 -0.29 0.016 0.0375 3553736 ACon1_001020 CC(NC(=O)c1ccccc1N)C(=O)N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C21 compound treatment 164000.0 -30400.0 -0.81 139200.0 -59700.0 -1.62 -1.7179 -0.9495 3558991 ACon1_001021 CCCCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C22 compound treatment 206400.0 12000.0 0.32 191040.0 -7860.0 -0.21 0.0765 0.1986 3559021 ACon1_001022 CC(=C)C(=O)O[C@H]1[C@@H]2[C@H](OC(=O)C2=C)/C=C(\CO)/CC/C=C(/C=O)\[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C23 compound treatment 108680.0 -85700.0 -2.29 100880.0 -98000.0 -2.65 -3.4978 -0.9974 1102980 ACon1_001023 COc1cc(cc(OC)c1OC)C2C3C(COC3=O)Cc4cc5OCOc5cc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 C24 compound treatment 195120.0 717.0 0.02 197480.0 -1420.0 -0.04 -0.0136 -0.3168 3552625 ACon1_001024 C[C@@H]1C[C@@H](O)[C@]23CO[C@]3(CO)CCC[C@@H]2[C@]41C[C@H](OC4=O)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D01 compound treatment 242560.0 48200.0 1.29 210160.0 11300.0 0.3 1.1264 0.8509 3558448 ACon1_001025 O[C@@H]1[C@@H](O)[C@H](Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)O[C@@H]([C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D02 compound treatment 280120.0 85700.0 2.29 242880.0 44000.0 1.19 2.4632 0.9534 1035250 ACon1_001026 CC(=O)c1c(O)cc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D03 compound treatment 235000.0 40600.0 1.09 252520.0 53600.0 1.45 1.7943 0.9898 3558681 ACon1_001027 CC(C)C1CCC(C)(O)C2CCC(C21)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D04 compound treatment 219880.0 25500.0 0.68 216640.0 17700.0 0.48 0.8215 0.9853 3559064 ACon1_001028 COc1cc2OC(C)(C)C=Cc2c3O[C@H](CC(=O)c13)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D05 compound treatment 301120.0 107000.0 2.85 249560.0 50700.0 1.37 2.9883 0.9436 3558585 ACon1_001029 COc1cc(C[C@H]2CO[C@@H]([C@H]2CO)c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D06 compound treatment 272400.0 78000.0 2.09 295880.0 97000.0 2.63 3.3318 0.9935 3555816 ACon1_001030 OC(=O)C(CCCCCCCCC=C)C1(CCC(=O)O1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D07 compound treatment 166240.0 -28200.0 -0.75 178840.0 -20100.0 -0.54 -0.9167 -0.9871 3557965 ACon1_001031 COc1cc2oc(c(OC)c(=O)c2c(O)c1OC)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D08 compound treatment 260360.0 66000.0 1.76 262600.0 63700.0 1.72 2.467 0.9999 3559355 ACon1_001032 COc1cc(CC(CO)C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)Cc3cc(OC)c(O)c(OC)c3)cc(OC)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D09 compound treatment 240840.0 46400.0 1.24 265440.0 66500.0 1.8 2.1521 0.9835 3558973 ACon1_001033 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D10 compound treatment 256760.0 62400.0 1.67 246960.0 48100.0 1.3 2.0995 0.9925 3554278 ACon1_001034 CCCCCC1OC2=C(C(O)C1(C)O)C(=O)N(OC)C2CSCC(O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D11 mock treatment 227320.0 32900.0 0.88 250160.0 51300.0 1.39 1.6039 0.9759 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D12 mock treatment 256440.0 62000.0 1.66 227400.0 28500.0 0.77 1.719 0.9393 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D13 compound treatment 235200.0 40800.0 1.09 241160.0 42300.0 1.14 1.5806 0.9997 3558978 ACon1_001035 C/C(=C\C(=O)O)/CCC1C(=C)CCC2C(C)(C)C(O)CCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D14 compound treatment 253840.0 59400.0 1.59 277640.0 78700.0 2.13 2.6316 0.9896 3558688 ACon1_001036 CC(C)(C=C)c1cc2cc3ccoc3cc2oc1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D15 mock treatment 260120.0 65700.0 1.76 244720.0 45800.0 1.24 2.1201 0.9854 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D16 mock treatment 247800.0 53400.0 1.43 260160.0 61300.0 1.66 2.1827 0.9972 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D17 compound treatment 273640.0 79200.0 2.12 275040.0 76100.0 2.06 2.9563 0.9999 3559116 ACon1_001037 OC(=O)[C@]1(O)C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H](OC(=O)/C=C/c3ccc(O)c(O)c3)[C@@H](C1)OC(=O)/C=C/c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D18 compound treatment 222160.0 27800.0 0.74 205600.0 6700.0 0.18 0.6533 0.8547 3558901 ACon1_001038 O[C@@H](CCc1ccccc1)CC(=O)CCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D19 compound treatment 291320.0 96900.0 2.59 268320.0 69400.0 1.88 3.162 0.9875 3554848 ACon1_001039 COc1cc(C)c(Oc2cc(C)cc(O)c2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D20 compound treatment 233320.0 38900.0 1.04 207920.0 9020.0 0.24 0.9088 0.8499 3559313 ACon1_001040 COC(=O)C[C@H]1/C(=C/COC(=O)\C=C\c2ccccc2)/[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D21 compound treatment 241520.0 47100.0 1.26 216160.0 17300.0 0.47 1.2216 0.9088 3552014 ACon1_001041 C/C=C(/C)\C(=O)O[C@H]1C(=C)[C@@H]2C[C@]31CC[C@@H]4[C@@](C)(CCC[C@@]4(C)[C@]3(O)CC2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D22 compound treatment 257480.0 63100.0 1.69 207480.0 8580.0 0.23 1.3573 0.7969 3559586 ACon1_001042 CC(=O)OC/C/1=C\[C@H]2OC(=O)C(=C)[C@@H]2CC\C(=C\CC1)\CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D23 compound treatment 243040.0 48600.0 1.3 213520.0 14600.0 0.4 1.1998 0.8823 3554758 ACon1_001043 COc1c(ccc2Oc3c(O)cc(C)cc3COC(=O)c12)C(O)CC(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 D24 compound treatment 238360.0 44000.0 1.18 176240.0 -22700.0 -0.61 0.3976 0.2998 3557336 ACon1_001044 CC(O)CC1=CC(OC1=O)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E01 mock treatment 205800.0 11400.0 0.3 197880.0 -1020.0 -0.03 0.1961 0.6405 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E02 mock treatment 205320.0 10900.0 0.29 213560.0 14700.0 0.4 0.4871 0.9886 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E03 compound treatment 213720.0 19300.0 0.52 211320.0 12400.0 0.34 0.6031 0.9783 3553538 ACon1_001045 CC(C)C(NC(=O)C(Cc1ccccc1)NC(=O)C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E04 compound treatment 183920.0 -10500.0 -0.28 185760.0 -13100.0 -0.36 -0.4498 -0.9931 3555006 ACon1_001046 COc1cc(OC)c2C(=O)OC(C)Cc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E05 compound treatment 191440.0 -2960.0 -0.08 190200.0 -8700.0 -0.24 -0.2226 -0.8957 3558819 ACon1_001047 O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3[C@H](O)CC2=C)C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E06 compound treatment 219400.0 25000.0 0.67 206640.0 7740.0 0.21 0.621 0.8862 3614704 ACon1_001048 Cc1c(O)cc2C(=O)C(O)(CCCO)OCc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E07 compound treatment 196320.0 1920.0 0.05 177120.0 -21800.0 -0.59 -0.3807 -0.6432 3558866 ACon1_001049 C[C@@H]1O[C@@H](OC[C@H]2O[C@H]([C@H](O)[C@@H](O)[C@@H]2O)c3c(O)cc4oc(cc(=O)c4c3O)c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E08 compound treatment 221000.0 26600.0 0.71 230440.0 31500.0 0.85 1.1068 0.9959 3558836 ACon1_001050 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E09 mock treatment 202000.0 7600.0 0.2 188120.0 -10800.0 -0.29 -0.0627 -0.1762 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E10 mock treatment 187720.0 -6680.0 -0.18 198160.0 -740.0 -0.02 -0.1406 -0.7814 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E11 compound treatment 187920.0 -6480.0 -0.17 205760.0 6860.0 0.19 0.0087 0.0343 3558576 ACon1_001051 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)C(C)(C)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E12 compound treatment 208000.0 13600.0 0.36 200600.0 1700.0 0.05 0.2897 0.7903 3558478 ACon1_001052 CC(C)(O)c1cc(O)c2c(CCC3C(C)(CCCC32C)C(=O)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E13 compound treatment 206040.0 11600.0 0.31 209240.0 10300.0 0.28 0.4181 0.9986 3558756 ACon1_001053 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCC(C)[C@@H]3C[C@H]4OC(=O)C5=CO[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)/C(=C/C)/[C@@H]5CC(=O)OC[C@@H]3[C@H]4C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E14 compound treatment 207320.0 12900.0 0.35 210680.0 11800.0 0.32 0.4698 0.9992 1859 ACon1_001054 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E15 compound treatment 195920.0 1520.0 0.04 192680.0 -6220.0 -0.17 -0.0904 -0.5217 3558832 ACon1_001055 C/C/1=C\CC\C(=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@@H](O)C1)\CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E16 compound treatment 241320.0 46900.0 1.25 242240.0 43300.0 1.17 1.7171 0.9994 3555940 ACon1_001056 OC1CCC(=O)C(O)C1(O)C(=O)OCc2cc(O)ccc2OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E17 mock treatment 176600.0 -17800.0 -0.48 202640.0 3740.0 0.1 -0.2651 -0.5446 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E18 mock treatment 186200.0 -8200.0 -0.22 208680.0 9780.0 0.26 0.0321 0.0933 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E19 compound treatment 188240.0 -6160.0 -0.16 212320.0 13400.0 0.36 0.1403 0.3518 3557853 ACon1_001057 CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C5CCC43C)C(=O)O)C2C1(C)O)C(=O)OC6OC(CO)C(O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E20 compound treatment 208680.0 14300.0 0.38 197880.0 -1020.0 -0.03 0.2505 0.6543 3558986 ACon1_001058 COc1cc(CCC(O)CC(O)CCc2ccc(O)c(OC)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E21 compound treatment 14440.0 -180000.0 -4.81 13960.0 -185000.0 -5.01 -6.9442 -0.9998 3559000 ACon1_001059 CCCCCCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E22 compound treatment 224560.0 30200.0 0.81 197760.0 -1140.0 -0.03 0.5486 0.6796 3559026 ACon1_001060 CC1(C)[C@@H](O)CC[C@@]2(C)[C@@H]3CC[C@@](C)(C=C3CC[C@H]12)C(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E23 compound treatment 205880.0 11500.0 0.31 197000.0 -1900.0 -0.05 0.1807 0.5806 3558682 ACon1_001061 CC(C)c1ccc2c(c1)C(O)CC3C(C)(CO)CCCC32C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 E24 compound treatment 204080.0 9680.0 0.26 202960.0 4060.0 0.11 0.2608 0.9272 3552689 ACon1_001062 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@@H](O)C(C)(C)C5CC[C@]43C)C2[C@]1(C)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F01 mock treatment 232240.0 37800.0 1.01 231080.0 32200.0 0.87 1.3317 0.9972 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F02 mock treatment 197160.0 2760.0 0.07 228240.0 29300.0 0.79 0.6138 0.7695 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F03 compound treatment 157720.0 -36700.0 -0.98 154280.0 -44600.0 -1.21 -1.548 -0.9947 3558778 ACon1_001063 Oc1ccc(/C=C/c2cc(O)cc(O)c2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F04 compound treatment 192000.0 -2400.0 -0.06 221880.0 23000.0 0.62 0.3945 0.6307 3559033 ACon1_001064 COc1cc(ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F05 compound treatment 193600.0 -803.0 -0.02 192560.0 -6340.0 -0.17 -0.1365 -0.7894 425 ACon1_001065 Oc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F06 compound treatment 227880.0 33500.0 0.9 246680.0 47800.0 1.29 1.5479 0.9839 3559139 ACon1_001066 C[C@]1(CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@@]3(CCC12)C(=O)C4=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F07 compound treatment 156680.0 -37700.0 -1.01 159880.0 -39000.0 -1.06 -1.4605 -0.9997 3558995 ACon1_001067 CCCCCCCC(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F08 compound treatment 218680.0 24300.0 0.65 220320.0 21400.0 0.58 0.8692 0.9984 3557648 ACon1_001068 OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)/C=C/c2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F09 mock treatment 172360.0 -22000.0 -0.59 192840.0 -6060.0 -0.16 -0.5329 -0.8708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F10 mock treatment 179720.0 -14700.0 -0.39 201400.0 2500.0 0.07 -0.2298 -0.5767 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F11 compound treatment 183400.0 -11000.0 -0.29 206720.0 7820.0 0.21 -0.0584 -0.1611 3558481 ACon1_001069 COc1cc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F12 compound treatment 191440.0 -2960.0 -0.08 179760.0 -19100.0 -0.52 -0.4224 -0.8059 3557470 ACon1_001070 CCc1cc(O)c(C)c(O)c1C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F13 compound treatment 194320.0 -82.7 0.0 194720.0 -4180.0 -0.11 -0.0816 -0.7208 3559015 ACon1_001071 Oc1ccc(cc1)[C@H]2CC(=O)c3c(O)cc(O)c([C@H]4[C@@H](Oc5cc(O)cc(O)c5C4=O)c6ccc(O)cc6)c3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F14 compound treatment 215560.0 21200.0 0.57 239640.0 40700.0 1.1 1.1801 0.9519 3555967 ACon1_001072 OCC1OC(OC(CCc2ccccc2)CC(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F15 compound treatment 200120.0 5720.0 0.15 214600.0 15700.0 0.43 0.4087 0.9047 3557355 ACon1_001073 CCCC[C@@H](O)c1cc(OC)cc(=O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F16 compound treatment 178600.0 -15800.0 -0.42 196680.0 -2220.0 -0.06 -0.3414 -0.7996 3558989 ACon1_001074 CCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F17 mock treatment 189800.0 -4600.0 -0.12 208280.0 9380.0 0.25 0.0925 0.3278 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F18 mock treatment 178880.0 -15500.0 -0.42 218800.0 19900.0 0.54 0.0874 0.1284 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F19 compound treatment 200960.0 6560.0 0.18 197760.0 -1140.0 -0.03 0.1022 0.5739 3559597 ACon1_001075 COc1cc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O)c(OC)c3)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F20 compound treatment 99800.0 -94600.0 -2.53 92880.0 -106000.0 -2.87 -3.8189 -0.998 3552025 ACon1_001076 C/C=C(\C)/C(=O)O[C@H]1C=CC(=O)O[C@H]1\C=C\[C@H](O)[C@H](C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F21 compound treatment 23760.0 -171000.0 -4.56 13600.0 -185000.0 -5.02 -6.7748 -0.9989 3553341 ACon1_001077 CC(=O)O[C@@H]1CC2[C@@]3(C)CCC(OC(=O)CC(=O)O)C(C)(C)C3CC[C@@]2(C)[C@]4(C)CCC(O)(C14)[C@]5(C)CCC(O5)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F22 compound treatment 144840.0 -49600.0 -1.33 138240.0 -60700.0 -1.64 -2.0987 -0.9944 3555308 ACon1_001078 COc1cccc2C(=O)c3c(ccc4CC(C)(O)CC(=O)c43)C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F23 compound treatment 112120.0 -82300.0 -2.2 105000.0 -93900.0 -2.54 -3.3539 -0.9974 3559897 ACon1_001079 CC(=CCc1c(O)cc(O)c2c(=O)cc(oc12)c3ccc(O)cc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 F24 compound treatment 209800.0 15400.0 0.41 216400.0 17500.0 0.47 0.6262 0.9976 3558760 ACon1_001080 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@@H](O)C[C@@]31O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G01 compound treatment 210000.0 15600.0 0.42 199760.0 860.0 0.02 0.3115 0.7454 3558179 ACon1_001081 COc1cc(CCCO)cc2C(COC3OC(CO)C(O)C(O)C3O)C(Oc21)c4ccc(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G02 compound treatment 17240.0 -177000.0 -4.74 17560.0 -181000.0 -4.91 -6.8223 -0.9998 3554828 ACon1_001082 COc1cc(c(O)c(O)c1c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G03 mock treatment 174280.0 -20100.0 -0.54 204600.0 5700.0 0.15 -0.2715 -0.4848 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G04 mock treatment 248640.0 54200.0 1.45 209040.0 10100.0 0.27 1.22 0.8262 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G05 compound treatment 175280.0 -19100.0 -0.51 190360.0 -8540.0 -0.23 -0.5252 -0.9356 3555886 ACon1_001083 OC[C@H]1O[C@@H](O[C@H]2C[C@@H]3[C@@H]([C@H]4OC(=O)C(=C)[C@@H]4[C@H](O)CC3=C)C2=C)[C@H](O)[C@@H](O)[C@@H]1OC(=O)/C=C/c5ccc(O)c(O)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G06 compound treatment 187400.0 -7000.0 -0.19 196360.0 -2540.0 -0.07 -0.1811 -0.9075 3614713 ACon1_001084 CC1CC(O)c2c(C1)ccc3C(O)c4c(O)cccc4C(=O)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G07 compound treatment 171560.0 -22800.0 -0.61 173560.0 -25300.0 -0.69 -0.9171 -0.9983 3558875 ACon1_001085 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3CC=C(CO)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G08 compound treatment 187080.0 -7320.0 -0.2 191160.0 -7740.0 -0.21 -0.2867 -0.9994 3558860 ACon1_001086 C/C(=C\CCC(C)(O)C=C)/C(=O)OCC1CCC2C1C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G09 compound treatment 182640.0 -11800.0 -0.31 188720.0 -10200.0 -0.28 -0.4174 -0.9978 3558972 ACon1_001087 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@H]1C)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G10 compound treatment 198800.0 4400.0 0.12 206240.0 7340.0 0.2 0.2237 0.9687 3557781 ACon1_001088 O[C@H]1[C@@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G11 compound treatment 18760.0 -176000.0 -4.7 19560.0 -179000.0 -4.86 -6.7553 -0.9999 1105254 ACon1_001089 CC12CCC3C4(C)C=CC(=O)C(C)(C)C4CC(O)C3(C)C2=CCC1c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G12 compound treatment 213000.0 18600.0 0.5 228760.0 29900.0 0.81 0.9234 0.9728 3558250 ACon1_001090 CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H]2Oc3cc4oc(=O)ccc4cc3[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G13 compound treatment 177880.0 -16500.0 -0.44 197400.0 -1500.0 -0.04 -0.3412 -0.7688 3553160 ACon1_001091 C[C@H]1OC(=O)[C@@H](C)[C@@H]1C[C@@H](O)[C@](C)(O)[C@H]2CC[C@@]3(O)C4=CC(=O)[C@@H]5C[C@@H](O)[C@@H](O)C[C@]5(C)C4CC[C@]23C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G14 compound treatment 175240.0 -19200.0 -0.51 210120.0 11200.0 0.3 -0.1477 -0.2478 3558272 ACon1_001092 C[C@H]1[C@H](C[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O)OC(=O)/C=C/c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G15 compound treatment 32480.0 -162000.0 -4.33 34680.0 -164000.0 -4.45 -6.2063 -0.9999 3558437 ACon1_001093 CO[C@@H]1CC(OC2CCC3(C)C(CCC4(CCC(C5=CC(=O)OC5)C6(C)CCC34)C6=O)C2)O[C@H](C)[C@@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G16 compound treatment 220200.0 25800.0 0.69 234520.0 35600.0 0.96 1.1698 0.9865 3559145 ACon1_001094 CC(C)(O)CC(O)CC(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G17 compound treatment 193280.0 -1120.0 -0.03 183640.0 -15300.0 -0.41 -0.3134 -0.7565 3557962 ACon1_001095 OC[C@H]1O[C@@H](O[C@@H]2OC=CC3C(O)C=C(COC(=O)c4ccccc4)C32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G18 compound treatment 169360.0 -25000.0 -0.67 193800.0 -5100.0 -0.14 -0.5713 -0.8353 3558116 ACon1_001096 COc1c(O)c2c(=O)cc(oc2cc1O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G19 mock treatment 201640.0 7240.0 0.19 217280.0 18400.0 0.5 0.4887 0.9154 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G20 mock treatment 199680.0 5280.0 0.14 205200.0 6300.0 0.17 0.2204 0.9956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G21 compound treatment 213440.0 19000.0 0.51 205920.0 7020.0 0.19 0.4945 0.9097 3554700 ACon1_001097 COC(=O)c1cc(CO)cc(O)c1C(=O)c2c(O)cccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G22 compound treatment 190400.0 -4000.0 -0.11 196960.0 -1940.0 -0.05 -0.1128 -0.9462 3558581 ACon1_001098 C[C@@]1(CCC[C@]2(C)C3CCC4CC3(CCC12)C=C4CO)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G23 compound treatment 131840.0 -62600.0 -1.67 118600.0 -80300.0 -2.17 -2.7205 -0.9916 3555287 ACon1_001099 COc1ccc2c(C=O)c(oc2c1)c3ccc(OC)c(O)c3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 G24 compound treatment 10160.0 -184000.0 -4.93 9320.0 -190000.0 -5.13 -7.114 -0.9998 1787154 ACon1_001100 CC(=CCc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccccc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H01 compound treatment 224240.0 29800.0 0.8 210600.0 11700.0 0.32 0.7883 0.9181 3558364 ACon1_001101 CCCCCOC(=O)c1ccccc1C(=O)OCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H02 compound treatment 232920.0 38500.0 1.03 201680.0 2780.0 0.08 0.7818 0.7567 3558698 ACon1_001102 CC(=O)OC/C=C(\CO)/CC/C=C(\C)/CC/C=C(\CC/C=C(\C)/COC(=O)C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H03 mock treatment 189000.0 -5400.0 -0.14 195920.0 -2980.0 -0.08 -0.1592 -0.9621 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H04 mock treatment 181760.0 -12600.0 -0.34 207760.0 8860.0 0.24 -0.0695 -0.1677 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H05 compound treatment 198640.0 4240.0 0.11 210800.0 11900.0 0.32 0.308 0.9017 3558811 ACon1_001103 COc1cc(/C=C/C=O)cc(OC)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H06 compound treatment 209160.0 14800.0 0.39 216600.0 17700.0 0.48 0.618 0.9954 3559864 ACon1_001104 OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](C[C@@H]4N(Cc5c4nc6ccccc6c5O)C3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H07 compound treatment 171600.0 -22800.0 -0.61 177360.0 -21500.0 -0.58 -0.8436 -0.9997 3557308 ACon1_001105 CCCCCCCCC(C(O)CC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H08 compound treatment 190000.0 -4400.0 -0.12 209360.0 10500.0 0.28 0.117 0.3814 1001923 ACon1_001106 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H09 compound treatment 177280.0 -17100.0 -0.46 181960.0 -16900.0 -0.46 -0.6481 -1.0 3557902 ACon1_001107 COc1cc(cc(OC)c1O)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4cc(OC)c(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H10 compound treatment 87680.0 -107000.0 -2.85 103040.0 -95900.0 -2.6 -3.8536 -0.9989 3553984 ACon1_001108 Cc1cc(O)c(Cc2c(O)cc(C)c(C=O)c2O)c(O)c1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H11 compound treatment 160520.0 -33900.0 -0.91 172080.0 -26800.0 -0.73 -1.1543 -0.994 3559002 ACon1_001109 Oc1ccc(CCCc2ccc3OCOc3c2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H12 compound treatment 211480.0 17100.0 0.46 206560.0 7660.0 0.21 0.4696 0.9362 3554509 ACon1_001110 CO[C@H]/1\C=C\[C@@](C)(O)/C=C/C(=O)O[C@H](C)[C@@H](C)CC\C=C1/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H13 compound treatment 175240.0 -19200.0 -0.51 177800.0 -21100.0 -0.57 -0.7664 -0.9985 3559031 ACon1_001111 CC(C)(O)CCC(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)C3CC=C4C(C[C@H](O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H14 compound treatment 20560.0 -174000.0 -4.65 20120.0 -179000.0 -4.84 -6.7105 -0.9998 3554525 ACon1_001112 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)C(C)(O)CCl)C1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H15 compound treatment 165680.0 -28700.0 -0.77 164560.0 -34300.0 -0.93 -1.2006 -0.9955 3553997 ACon1_001113 Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H16 compound treatment 203000.0 8600.0 0.23 213200.0 14300.0 0.39 0.4364 0.9691 1106761 ACon1_001114 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C(C=C)C1CC3CC(=O)CC(CC(=O)CCc4ccc(O)cc4)O3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H17 compound treatment 230240.0 35800.0 0.96 255240.0 56300.0 1.53 1.7564 0.9749 3559112 ACon1_001115 C[C@@H]([C@H]1CC[C@](C)(O1)C=C)C(=O)/C=C/C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H18 compound treatment 168360.0 -26000.0 -0.7 193760.0 -5140.0 -0.14 -0.591 -0.8319 3558839 ACon1_001116 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H19 mock treatment 191520.0 -2880.0 -0.08 215160.0 16300.0 0.44 0.2568 0.5745 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H20 mock treatment 183120.0 -11300.0 -0.3 169320.0 -29600.0 -0.8 -0.7797 -0.911 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H21 compound treatment 189080.0 -5320.0 -0.14 188720.0 -10200.0 -0.28 -0.2955 -0.9528 1111461 ACon1_001117 CC(=CCOc1c2occc2cc3ccc(=O)oc13)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H22 compound treatment 14640.0 -180000.0 -4.81 13920.0 -185000.0 -5.01 -6.9412 -0.9998 3558469 ACon1_001118 OC(=O)c1c(O)cccc1CCCCCCC/C=C\C/C=C\CC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H23 compound treatment 223880.0 29500.0 0.79 208360.0 9460.0 0.26 0.7386 0.891 3559898 ACon1_001119 C[C@@H]1C(O)O[C@@H]2[C@H]1[C@@H](O)C[C@](C)(C=C)[C@H]2C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 H24 compound treatment 217120.0 22700.0 0.61 213480.0 14600.0 0.39 0.7088 0.9782 3559171 ACon1_001120 OC[C@H]1O[C@@H](Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4C(=O)C[C@@H](Oc4c2)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I01 compound treatment 9560.0 -185000.0 -4.94 9600.0 -189000.0 -5.12 -7.12 -0.9998 3554132 ACon1_001121 CCC(C)C(=O)c1c(O)cc2OC(C)(C)C(CC=C(C)C)Cc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I02 compound treatment 12200.0 -182000.0 -4.87 11680.0 -187000.0 -5.07 -7.0302 -0.9998 3553195 ACon1_001122 CC(=CCc1c(oc2c(CC=C(C)C)c(O)cc(O)c2c1=O)c3ccc(O)cc3O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I03 compound treatment 24400.0 -170000.0 -4.55 24120.0 -175000.0 -4.73 -6.5613 -0.9998 3559282 ACon1_001123 OC[C@H]1O[C@@H](Oc2ccc(CC=C)cc2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I04 compound treatment 228640.0 34200.0 0.92 251160.0 52300.0 1.41 1.648 0.9778 3558801 ACon1_001124 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H]3C(=C[C@@H](O)[C@@]3(C)O)[C@@](C)(O)C[C@@H]2OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I05 mock treatment 168080.0 -26300.0 -0.7 216240.0 17300.0 0.47 -0.1659 -0.1961 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I06 mock treatment 184440.0 -9960.0 -0.27 216720.0 17800.0 0.48 0.1527 0.2771 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I07 compound treatment 189880.0 -4520.0 -0.12 234160.0 35300.0 0.95 0.5895 0.6126 3474459 ACon1_001125 OCC1OC(Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)C(OC5OCC(O)(CO)C5O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I08 compound treatment 173800.0 -20600.0 -0.55 216760.0 17900.0 0.48 -0.0478 -0.0652 3554178 ACon1_001126 CCC(CCCCC(=O)CCCCC1CCC(=O)O1)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](OC(=O)/C=C/c4ccc(O)cc4)[C@H](OC(=O)C)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I09 compound treatment 17680.0 -177000.0 -4.73 18520.0 -180000.0 -4.88 -6.7956 -0.9999 3558998 ACon1_001127 CCCCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I10 compound treatment 192560.0 -1840.0 -0.05 216320.0 17400.0 0.47 0.2986 0.6298 3557509 ACon1_001128 OCC1OC(C(O)C(O)C1O)c2c(O)c(C3OCC(O)C(O)C3O)c(O)c4c(=O)cc(oc24)c5ccc(O)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I11 compound treatment 224720.0 30300.0 0.81 246400.0 47500.0 1.29 1.4827 0.9753 3558722 ACon1_001129 CC1OC(OCC2OC(OCCc3ccc(O)c(O)c3)C(OC(=O)C)C(OC4OC(C)C(O)C(O)C4O)C2OC(=O)/C=C/c5ccc(O)c(O)c5)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I12 compound treatment 208040.0 13600.0 0.36 242480.0 43600.0 1.18 1.0922 0.8844 3558629 ACon1_001130 OC[C@H]1O[C@@H](Oc2cc3occc3cc2CCC(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I13 compound treatment 201920.0 7520.0 0.2 240000.0 41100.0 1.11 0.929 0.8216 3558785 ACon1_001131 CC1(C)C2CCC1(C)C(C2)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I14 compound treatment 205120.0 10700.0 0.29 206920.0 8020.0 0.22 0.3562 0.9906 3558926 ACon1_001132 Oc1ccc(/C=C/c2ccc(O)cc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I15 compound treatment 199840.0 5440.0 0.15 223400.0 24500.0 0.66 0.5719 0.8421 3558862 ACon1_001133 CC1CCC2C1C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)OC4C5OC5(C)C6C(OC7OC(CO)C(OC(=O)/C(=C/CCC(C)(O)C=C)/C)C(O)C7O)OC=CC46O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I16 compound treatment 203080.0 8680.0 0.23 217680.0 18800.0 0.51 0.5236 0.9369 3558948 ACon1_001134 COc1cc(/C=C\C(=O)O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I17 compound treatment 194360.0 -42.7 0.0 223200.0 24300.0 0.66 0.4644 0.7059 3557339 ACon1_001135 C[C@H]1OC(=O)c2c(O)ccc(O)c2[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I18 compound treatment 179320.0 -15100.0 -0.4 225720.0 26800.0 0.73 0.2281 0.2747 3557346 ACon1_001136 CC(C)CCCC/C=C\CCCCCCCC(=O)OCC(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I19 compound treatment 206880.0 12500.0 0.33 224520.0 25600.0 0.69 0.7265 0.9438 3557913 ACon1_001137 CC1OC(OC2C(O)C(O)COC2OC3C(O)C(O)C(OC3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7C8CC(C)(C)CC(O)[C@]8(C)CC[C@]76C)C4(C)C)C(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I20 compound treatment 226440.0 32000.0 0.86 238920.0 40000.0 1.08 1.3721 0.9933 3558986 ACon1_001138 COc1cc(CCC(O)CC(O)CCc2ccc(O)c(OC)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I21 mock treatment 190240.0 -4160.0 -0.11 192760.0 -6140.0 -0.17 -0.1963 -0.981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I22 mock treatment 233880.0 39500.0 1.06 204960.0 6060.0 0.16 0.8627 0.8073 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I23 compound treatment 13480.0 -181000.0 -4.84 13280.0 -186000.0 -5.03 -6.9754 -0.9998 3554969 ACon1_001139 COc1cc(O)c(CC=C(C)C)cc1C(=O)/C=C/c2ccc(O)c(CC=C(C)C)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 I24 compound treatment 216880.0 22500.0 0.6 234840.0 35900.0 0.97 1.1132 0.9732 3554553 ACon1_001140 COC(=O)[C@]1(C)CC[C@H](O)[C@@]2(C)C1C[C@@H](OC(=O)C)C3=C2[C@H](O)C[C@](C)(C=C)[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J01 compound treatment 223640.0 29200.0 0.78 217120.0 18200.0 0.49 0.9018 0.9753 3557527 ACon1_001141 OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J02 compound treatment 221600.0 27200.0 0.73 185040.0 -13900.0 -0.38 0.2491 0.3043 3558547 ACon1_001142 COc1ccc(cc1OC)[C@@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J03 compound treatment 213480.0 19100.0 0.51 179920.0 -19000.0 -0.51 -0.0025 -0.0034 3554707 ACon1_001143 COC(=O)c1cc(O)cc(OC)c1Oc2c(Cl)c(C)c(Cl)c(O)c2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J04 compound treatment 232840.0 38400.0 1.03 200320.0 1420.0 0.04 0.7542 0.733 3559048 ACon1_001144 CC(C)(O)C(O)Cc1cc2ccc(=O)oc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J05 mock treatment 204840.0 10400.0 0.28 224680.0 25800.0 0.7 0.6909 0.9192 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J06 mock treatment 195000.0 597.0 0.02 202920.0 4020.0 0.11 0.0883 0.8023 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J07 compound treatment 16120.0 -178000.0 -4.77 17080.0 -182000.0 -4.92 -6.8527 -0.9999 3559004 ACon1_001145 Oc1cc(O)c(C(=O)CCCCCCCCc2ccccc2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J08 compound treatment 153400.0 -41000.0 -1.1 166600.0 -32300.0 -0.87 -1.3939 -0.9937 3558537 ACon1_001146 C/C(=C\CC1C(=C)CCC2C(C)(CCCC12C)C(=O)O)/C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J09 compound treatment 183560.0 -10800.0 -0.29 185400.0 -13500.0 -0.37 -0.4635 -0.9934 3558931 ACon1_001147 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3O[C@@H](CC(=O)c3c2O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J10 compound treatment 205200.0 10800.0 0.29 209680.0 10800.0 0.29 0.4106 1.0 3557887 ACon1_001148 COc1cc(ccc1O)C2OCC3C(OCC23)c4ccc(OC5OC(CO)C(O)C(O)C5O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J11 compound treatment 191960.0 -2440.0 -0.07 221920.0 23000.0 0.62 0.3945 0.6295 3557666 ACon1_001149 CC(=O)OCC(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J12 compound treatment 119960.0 -74400.0 -1.99 117200.0 -81700.0 -2.21 -2.972 -0.9986 3554146 ACon1_001150 CCC(C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J13 compound treatment 188680.0 -5720.0 -0.15 213120.0 14200.0 0.38 0.164 0.3958 3559043 ACon1_001151 CC(C)(O)C1CCC(C)(O1)C2[C@H](O)C[C@@]3(C)C4CC=C5C(C[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)C5(C)C)[C@]4(C)C(=O)C[C@]23C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J14 compound treatment 193200.0 -1200.0 -0.03 196960.0 -1940.0 -0.05 -0.0599 -0.9723 3557343 ACon1_001152 CCC/C=C\CC(N)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J15 compound treatment 196680.0 2280.0 0.06 210560.0 11700.0 0.32 0.2663 0.8283 3559081 ACon1_001153 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3ccc(C=C)cc3)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J16 compound treatment 41880.0 -153000.0 -4.08 75920.0 -123000.0 -3.33 -5.2391 -0.9949 3552097 ACon1_001154 C/C=C/C=C/C=C/C(=O)O[C@@H]1C=C2CO[C@@H](O)[C@]2(O)[C@@]3(C)CCCC(C)(C)[C@H]13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J17 compound treatment 242160.0 47800.0 1.28 268880.0 70000.0 1.89 2.2429 0.9816 3559133 ACon1_001155 OC1C(O)c2ccc(O)c(O)c2OC1c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J18 compound treatment 186760.0 -7640.0 -0.2 202440.0 3540.0 0.1 -0.0768 -0.3401 3558873 ACon1_001156 O[C@H]1[C@@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J19 compound treatment 216760.0 22400.0 0.6 186400.0 -12500.0 -0.34 0.1836 0.2672 3554748 ACon1_001157 COC1=CC(=O)O[C@@H](/C=C/c2ccccc2)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J20 compound treatment 178520.0 -15900.0 -0.42 196200.0 -2700.0 -0.07 -0.3521 -0.8168 3558844 ACon1_001158 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J21 mock treatment 198200.0 3800.0 0.1 180600.0 -18300.0 -0.5 -0.2785 -0.5507 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J22 mock treatment 194040.0 -363.0 -0.01 181800.0 -17100.0 -0.46 -0.3342 -0.7218 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J23 compound treatment 193440.0 -963.0 -0.03 208600.0 9700.0 0.26 0.1675 0.6347 3555129 ACon1_001159 COc1ccc(cc1)C2(O)C(O)C(=O)Nc3ccccc32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 J24 compound treatment 226600.0 32200.0 0.86 241680.0 42800.0 1.16 1.4279 0.9894 3552652 ACon1_001160 C[C@@H]1C[C@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@H](COC(=O)C)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H]2O)[C@]4(C)[C@H](CCC=C4C)[C@@]1(C)CC[C@](C)(O[C@@H]5O[C@H](C)[C@H](O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)[C@H](O)[C@H]5O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K01 compound treatment 222520.0 28100.0 0.75 197080.0 -1820.0 -0.05 0.497 0.6594 3554770 ACon1_001161 COc1c(O)cc2C(Oc3cc4C(O)C(C)OC(=O)c4c(O)c3OC)C(C)OC(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K02 compound treatment 93440.0 -101000.0 -2.7 101280.0 -97600.0 -2.64 -3.7784 -0.9999 3558741 ACon1_001162 C[C@@]1(CCC[C@]2(C)[C@@H](CCc3ccoc3)C(=C)CCC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K03 compound treatment 229640.0 35200.0 0.94 214360.0 15500.0 0.42 0.9624 0.9332 3558575 ACon1_001163 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)[C@@](C)(CO)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K04 compound treatment 218840.0 24400.0 0.65 206440.0 7540.0 0.2 0.6066 0.8857 3553892 ACon1_001164 CC1[C@@H]2CC[C@@]3(C)[C@H](O)C[C@H](O)C(=C)C3[C@H]2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K05 compound treatment 196800.0 2400.0 0.06 192480.0 -6420.0 -0.17 -0.0775 -0.4186 3558807 ACon1_001165 C[C@H]1[C@@H]2CC/C(=C/C[C@H](O)/C(=C/[C@H]2OC1=O)/C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K06 compound treatment 177320.0 -17100.0 -0.46 208160.0 9260.0 0.25 -0.1458 -0.2798 3552732 ACon1_001166 C[C@@H]1N2[C@H]3N(C1=O)c4ccccc4[C@@]3(O)C[C@@H]5C(=O)N[C@]2(C)c6nc7ccccc7c(=O)n56 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K07 mock treatment 184200.0 -10200.0 -0.27 186720.0 -12200.0 -0.33 -0.4261 -0.9956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K08 mock treatment 179560.0 -14800.0 -0.4 180360.0 -18500.0 -0.5 -0.6356 -0.9933 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K09 compound treatment 234000.0 39600.0 1.06 249960.0 51100.0 1.38 1.7264 0.9914 3558702 ACon1_001167 CC(=CCC/C(=C/CC/C(=C/CC\C(=C\COC(=O)C)\COC(=O)C)/C)/C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K10 compound treatment 202960.0 8560.0 0.23 176120.0 -22800.0 -0.62 -0.2742 -0.4169 3558881 ACon1_001168 COc1cc(ccc1O)[C@H]2Oc3c(cc(CCCO)cc3O)[C@@H]2CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K11 compound treatment 183200.0 -11200.0 -0.3 224280.0 25400.0 0.69 0.274 0.3655 3558728 ACon1_001169 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)c([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)c(C(=O)CCc4ccc(O)cc4)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K12 compound treatment 189080.0 -5320.0 -0.14 211800.0 12900.0 0.35 0.1463 0.3879 3558883 ACon1_001170 COc1c(CCC(=O)O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc3occc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K13 compound treatment 186160.0 -8240.0 -0.22 199040.0 140.0 0.0 -0.1532 -0.6948 3558821 ACon1_001171 OCC1OC(OC2CC3C(C4OC(=O)C(=C)C4C(O)CC3=C)C2=C)C(O)C(OC(=O)/C=C/c5ccc(O)c(O)c5)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K14 compound treatment 221440.0 27000.0 0.72 189040.0 -9860.0 -0.27 0.3226 0.4185 3558928 ACon1_001172 CC(C)C1C(OC(=O)/C=C/c2ccccc2)C3OC1CC(C)(O)C(O)CCC3(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K15 mock treatment 198800.0 4400.0 0.12 181440.0 -17500.0 -0.47 -0.2511 -0.5154 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K16 mock treatment 177200.0 -17200.0 -0.46 196000.0 -2900.0 -0.08 -0.3809 -0.816 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K17 compound treatment 62520.0 -132000.0 -3.53 78760.0 -120000.0 -3.25 -4.7943 -0.9992 3558508 ACon1_001173 CC(C)C(=O)O[C@@H]1[C@@H](OC(=O)C)[C@@H](OC(=O)C)C(C)(C)/C=C/C(C)C(=O)C2(O)C[C@@](C)(OC(=O)C)[C@H](OC(=O)C)C2[C@H]3OC(=O)CC[C@]31OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K18 compound treatment 203440.0 9040.0 0.24 191960.0 -6940.0 -0.19 0.0381 0.1244 3558941 ACon1_001174 CC(C)CC(=O)c1c(O)cc(O)cc1OC2OC(COC(=O)c3cc(O)c(O)c(O)c3)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K19 compound treatment 31000.0 -163000.0 -4.37 36360.0 -163000.0 -4.4 -6.2022 -1.0 3558693 ACon1_001175 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)C(C)(O)C(C)Cl)C1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K20 compound treatment 180960.0 -13400.0 -0.36 173160.0 -25700.0 -0.7 -0.747 -0.9526 3558988 ACon1_001176 CCCCCC(O)CC(O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K21 compound treatment 41840.0 -153000.0 -4.08 42720.0 -156000.0 -4.23 -5.8754 -0.9998 3559019 ACon1_001177 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](C)O[C@@H](O[C@@H]4[C@@H](O)[C@@H](O)CO[C@H]4O[C@H]5CC[C@@]6(C)C(CC[C@]7(C)C6CC=C8[C@@H]9CC(C)(C)CC[C@@]9(CC[C@]87C)C(=O)O)[C@]5(C)CO)[C@@H]3O)O[C@H](CO)[C@H]2O[C@@H]%10O[C@H](CO)[C@@H](O[C@@H]%11OC[C@@H](O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K22 compound treatment 201560.0 7160.0 0.19 237000.0 38100.0 1.03 0.8647 0.8243 3559027 ACon1_001178 CC(=O)OC[C@]1(O)C[C@@]2(C[C@H]1CC[C@H]23)CC[C@@H]4[C@@](C)(CCC[C@@]34C)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K23 mock treatment 261280.0 66900.0 1.79 201080.0 2180.0 0.06 1.3067 0.73 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 K24 mock treatment 211520.0 17100.0 0.46 211040.0 12100.0 0.33 0.5562 0.9868 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L01 compound treatment 228920.0 34500.0 0.92 190120.0 -8780.0 -0.24 0.4848 0.5085 3554154 ACon1_001179 CCC(C)c1cnc(Cc2ccccc2)c(=O)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L02 compound treatment 280920.0 86500.0 2.31 282120.0 83200.0 2.25 3.2295 0.9999 3557616 ACon1_001180 COc1cc(cc(OC)c1O)C2C(COC3OCC(O)C(O)C3O)C(CO)Cc4cc(OC)c(O)c(OC)c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L03 compound treatment 169320.0 -25100.0 -0.67 190320.0 -8580.0 -0.23 -0.6387 -0.8995 3554516 ACon1_001181 CO[C@H]1C(=O)Nc2ccc(/C=C/C3(C)CCC(C)(C)CO3)c(O)c2[C@]1(O)c4ccc(OC)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L04 compound treatment 214400.0 20000.0 0.53 221320.0 22400.0 0.61 0.8074 0.998 3559072 ACon1_001182 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](OC(=O)/C=C/c4ccc(O)cc4)[C@@H](O)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L05 compound treatment 141160.0 -53200.0 -1.42 153520.0 -45400.0 -1.23 -1.8758 -0.9973 3557828 ACon1_001183 Oc1ccc(CCCCC(=O)CCc2ccc(O)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L06 compound treatment 14800.0 -180000.0 -4.8 14840.0 -184000.0 -4.98 -6.9205 -0.9998 2095398 ACon1_001184 CC(=CCCC1(C)Oc2ccc3c4cc(C)c(O)cc4[nH]c3c2C=C1)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L07 mock treatment 183280.0 -11100.0 -0.3 185080.0 -13800.0 -0.37 -0.4749 -0.9936 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L08 mock treatment 173680.0 -20700.0 -0.55 177640.0 -21300.0 -0.58 -0.7989 -0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L09 compound treatment 196600.0 2200.0 0.06 210160.0 11300.0 0.3 0.2571 0.8282 3558935 ACon1_001185 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L10 compound treatment 193360.0 -1040.0 -0.03 208960.0 10100.0 0.27 0.1729 0.6314 3558649 ACon1_001186 CC1=CCC2C(C)(C)CCC[C@]2(C)[C@]31CC[C@](C)(CC(=O)O)O3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L11 compound treatment 241360.0 47000.0 1.26 179920.0 -19000.0 -0.51 0.5248 0.3867 3557542 ACon1_001187 Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)c(C4C(Oc5cc(O)cc(O)c5C4=O)c6ccc(O)c(O)c6)c3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L12 compound treatment 199440.0 5040.0 0.13 189240.0 -9660.0 -0.26 -0.0896 -0.3047 3558613 ACon1_001188 OC[C@H]1O[C@@H](OCCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L13 compound treatment 61880.0 -133000.0 -3.54 56680.0 -142000.0 -3.85 -5.2291 -0.9991 3558939 ACon1_001189 CC(=O)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L14 compound treatment 16680.0 -178000.0 -4.75 18640.0 -180000.0 -4.88 -6.8122 -0.9999 3558993 ACon1_001190 CCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L15 mock treatment 186360.0 -8040.0 -0.22 169960.0 -28900.0 -0.78 -0.7061 -0.8691 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L16 mock treatment 173920.0 -20500.0 -0.55 181200.0 -17700.0 -0.48 -0.7262 -0.9978 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L17 compound treatment 222920.0 28500.0 0.76 197480.0 -1420.0 -0.04 0.5122 0.6706 3559131 ACon1_001191 C[C@@]1(CCC[C@@]2(C)C3CCC4CC3(C[C@@]4(O)CO)CCC12)C(=O)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L18 compound treatment 207680.0 13300.0 0.36 213560.0 14700.0 0.4 0.5318 0.9985 3559237 ACon1_001192 O[C@H]1[C@@H](Oc2c([C@H]3[C@@H](Oc4cc(O)cc(O)c4C3=O)c5ccc(O)cc5)c(O)cc(O)c2C1=O)c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L19 compound treatment 195600.0 1200.0 0.03 192000.0 -6900.0 -0.19 -0.1094 -0.5774 3559639 ACon1_001193 CC(=O)/C=C(\O)/C=C/c1ccc(O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L20 compound treatment 136560.0 -57800.0 -1.55 150680.0 -48200.0 -1.31 -2.0171 -0.9964 3554658 ACon1_001194 COC(=O)C1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(=C1c3ccc(O)c(O)c3)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L21 compound treatment 186760.0 -7640.0 -0.2 185240.0 -13700.0 -0.37 -0.406 -0.9609 3557983 ACon1_001195 CC1CCC2C1C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L22 compound treatment 186720.0 -7680.0 -0.21 202000.0 3100.0 0.08 -0.086 -0.3872 3554257 ACon1_001196 CCCCC[C@@H]1OC2=C([C@H](O)[C@]1(C)O)C(=O)N(OC)C2=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L23 mock treatment 197560.0 3160.0 0.08 197720.0 -1180.0 -0.03 0.0371 0.4113 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 L24 mock treatment 219120.0 24700.0 0.66 177440.0 -21500.0 -0.58 0.0567 0.0644 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M01 compound treatment 228800.0 34400.0 0.92 203360.0 4460.0 0.12 0.736 0.7931 2110684 ACon1_001197 COC(=O)[C@]12C(=O)C(C)C(=O)[C@]2(C)C(=C[C@@H]3[C@]1(C)CC[C@@H]4C(C)(C)[C@H](CC[C@]43C=O)OC(=O)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M02 compound treatment 210160.0 15800.0 0.42 195000.0 -3900.0 -0.11 0.2234 0.5141 3558775 ACon1_001198 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)O)C2(C)C)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M03 compound treatment 344280.0 150000.0 4.01 170680.0 -28200.0 -0.76 2.2946 0.5622 3557303 ACon1_001199 COc1cc(O)cc2CC(C)OC(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M04 compound treatment 188640.0 -5760.0 -0.15 167800.0 -31100.0 -0.84 -0.7043 -0.8229 3558815 ACon1_001200 C[C@@H]1O[C@@H](O[C@@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@]2(C)CO)[C@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M05 compound treatment 107120.0 -87300.0 -2.33 108520.0 -90400.0 -2.45 -3.381 -0.9997 3553725 ACon1_001201 CC(CO)C(=O)O[C@H]1C/C(=C/CC/C(=C/[C@H]2OC(=O)C(CN3CCCC3C(=O)O)[C@@H]21)/CO)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M06 compound treatment 178520.0 -15900.0 -0.42 201880.0 2980.0 0.08 -0.2434 -0.5628 3558829 ACon1_001202 CC1CCCC2=CC(OC2=O)C(C)(C)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M07 compound treatment 177440.0 -17000.0 -0.45 163520.0 -35400.0 -0.96 -0.9981 -0.9417 3558899 ACon1_001203 CC(C)C(=O)OCC1(CO1)c2ccc(C)cc2OC(=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M08 compound treatment 162680.0 -31700.0 -0.85 187600.0 -11300.0 -0.31 -0.8163 -0.905 3558868 ACon1_001204 CC(=O)CCCCCCCc1[nH]c2ccccc2c(=O)c1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M09 mock treatment 201880.0 7480.0 0.2 195480.0 -3420.0 -0.09 0.076 0.3447 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M10 mock treatment 167640.0 -26800.0 -0.72 194080.0 -4820.0 -0.13 -0.5985 -0.8224 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M11 compound treatment 16560.0 -178000.0 -4.76 16720.0 -182000.0 -4.93 -6.8513 -0.9998 3558753 ACon1_001205 CC(=CCc1c(oc2c3C=CC(C)(C)Oc3cc(O)c2c1=O)c4ccc(O)cc4O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M12 compound treatment 194200.0 -203.0 -0.01 188720.0 -10200.0 -0.28 -0.1987 -0.7209 3558895 ACon1_001206 C[C@H]1O[C@@H](OC(C)(C)C2CCC(=CC2)C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M13 mock treatment 191120.0 -3280.0 -0.09 178480.0 -20400.0 -0.55 -0.453 -0.8093 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M14 mock treatment 182240.0 -12200.0 -0.33 173560.0 -25300.0 -0.69 -0.7151 -0.9419 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M15 compound treatment 207680.0 13300.0 0.36 176120.0 -22800.0 -0.62 -0.1849 -0.2599 3558864 ACon1_001207 C/C(=C\CC[C@@](C)(O)C=C)/C(=O)O[C@@H]1[C@@H]2O[C@]2(C)[C@H]3[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C[C@@]13OC(=O)\C(=C\CC[C@](C)(O)C=C)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M16 compound treatment 51960.0 -142000.0 -3.81 55600.0 -143000.0 -3.88 -5.4374 -1.0 3558691 ACon1_001208 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)C(=C)CO)C1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M17 compound treatment 209480.0 15100.0 0.4 193960.0 -4940.0 -0.13 0.1906 0.4486 3558897 ACon1_001209 CC(C)C(=O)OCC(O)(COC(=O)C(C)C)c1ccc(C)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M18 compound treatment 184320.0 -10100.0 -0.27 184080.0 -14800.0 -0.4 -0.4744 -0.9813 3558942 ACon1_001210 CC1=CCC(CC1)C(C)(C)O[C@@H]2O[C@H](COC(=O)c3cc(O)c(O)c(O)c3)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M19 compound treatment 11760.0 -183000.0 -4.89 11480.0 -187000.0 -5.07 -7.0424 -0.9998 3553659 ACon1_001211 CC(C)CCCC/C=C\CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M20 compound treatment 12480.0 -182000.0 -4.87 11840.0 -187000.0 -5.06 -7.0218 -0.9998 3558700 ACon1_001212 CC(=O)OC/C=C(\C)/CC/C=C(\C)/C(C/C=C(\CC/C=C(\C)/COC(=O)C)/C(=O)O)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M21 compound treatment 244640.0 50200.0 1.34 242360.0 43500.0 1.18 1.7822 0.9978 3614729 ACon1_001213 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccc(O)cc6)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M22 compound treatment 12360.0 -182000.0 -4.87 11640.0 -187000.0 -5.07 -7.0279 -0.9998 3559009 ACon1_001214 CCCCCCCC/C=C\CCCCCCCc1cccc(O)c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M23 compound treatment 205240.0 10800.0 0.29 230280.0 31400.0 0.85 0.8057 0.8976 3558724 ACon1_001215 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](OC(=O)C)[C@@H](O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H]2OC(=O)/C=C/c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 M24 compound treatment 10280.0 -184000.0 -4.93 11320.0 -188000.0 -5.08 -7.0734 -0.9999 3558423 ACon1_001216 C[C@]1(CCC[C@@]2(C)C3CCC4CC3(CC4=C)CCC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N01 compound treatment 25520.0 -169000.0 -4.52 37920.0 -161000.0 -4.36 -6.2759 -0.9998 1000005 ACon1_001217 CCCCCC(O)/C=C/C=C\CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N02 compound treatment 12400.0 -182000.0 -4.87 12440.0 -186000.0 -5.05 -7.0119 -0.9998 2119184 ACon1_001218 CC(=CCC/C(=C/Cc1cc2ccc(=O)oc2cc1O)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N03 compound treatment 184800.0 -9600.0 -0.26 196080.0 -2820.0 -0.08 -0.2356 -0.8792 3553469 ACon1_001219 CC(C)(O)C1=CC23CC[C@H]4[C@@](C)(CCC[C@]4(C)C3C[C@@H]1OO2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N04 compound treatment 208200.0 13800.0 0.37 200280.0 1380.0 0.04 0.2874 0.7747 3614731 ACon1_001220 CC1=C[C@@H](O)[C@H]2C(C)(C)CCC[C@]2(C)[C@@]1(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N05 compound treatment 193000.0 -1400.0 -0.04 201400.0 2500.0 0.07 0.0213 0.2757 3558777 ACon1_001221 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)O)C2(C)C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N06 compound treatment 206240.0 11800.0 0.32 219720.0 20800.0 0.56 0.6225 0.9628 3559649 ACon1_001222 Oc1ccc(/C=C/C(=O)c2c(O)cc(O)cc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N07 compound treatment 178240.0 -16200.0 -0.43 184680.0 -14200.0 -0.38 -0.5779 -0.9983 3553701 ACon1_001223 CC(CCC=C(C)C)C1CC(O)C(C)(O)C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N08 compound treatment 183000.0 -11400.0 -0.31 168360.0 -30500.0 -0.83 -0.8003 -0.9081 3557653 ACon1_001224 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N09 mock treatment 161360.0 -33000.0 -0.88 172720.0 -26200.0 -0.71 -1.1261 -0.994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N10 mock treatment 169920.0 -24500.0 -0.65 176360.0 -22500.0 -0.61 -0.8946 -0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N11 compound treatment 173160.0 -21200.0 -0.57 163920.0 -35000.0 -0.95 -1.0714 -0.9701 3559029 ACon1_001225 CC(C)(O)CCC(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)C3CC=C4C(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N12 compound treatment 186280.0 -8120.0 -0.22 194400.0 -4500.0 -0.12 -0.2398 -0.9626 1077975 ACon1_001226 COc1cc(CCC(=O)O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N13 mock treatment 173480.0 -20900.0 -0.56 193160.0 -5740.0 -0.16 -0.5056 -0.8705 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N14 mock treatment 184960.0 -9440.0 -0.25 188160.0 -10700.0 -0.29 -0.3842 -0.9975 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N15 compound treatment 185320.0 -9080.0 -0.24 164720.0 -34200.0 -0.93 -0.8261 -0.8635 2060475 ACon1_001227 COc1cc(OC)c2C(=O)CC(Oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N16 compound treatment 185200.0 -9200.0 -0.25 181720.0 -17200.0 -0.47 -0.5029 -0.9557 3558625 ACon1_001228 COc1c(O)cc(cc1O)c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N17 compound treatment 196680.0 2280.0 0.06 168360.0 -30500.0 -0.83 -0.5416 -0.6532 3559125 ACon1_001229 COc1ccc(cc1OC)C2OCC3[C@@H](OCC23)c4ccc(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N18 compound treatment 172440.0 -22000.0 -0.59 172000.0 -26900.0 -0.73 -0.9304 -0.9943 3559207 ACon1_001230 CC1(C)C(O)CCC2(C)C3CCC4CC3(CCC12)C=C4CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N19 compound treatment 24320.0 -170000.0 -4.55 36320.0 -163000.0 -4.4 -6.3293 -0.9999 3559663 ACon1_001231 CC(=CCc1c(O)cc(O)c(C(=O)/C=C/c2ccc(O)cc2)c1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N20 compound treatment 84280.0 -110000.0 -2.95 89880.0 -109000.0 -2.95 -4.1699 -1.0 3559567 ACon1_001232 COC(=O)[C@]1(C)CCC[C@]2(C)[C@@H](CCc3ccoc3)C(=CC[C@@H]12)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N21 compound treatment 180480.0 -13900.0 -0.37 185440.0 -13500.0 -0.36 -0.521 -0.9999 3558313 ACon1_001233 COc1cc(/C=C/C(=O)NCCc2ccc(O)cc2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N22 compound treatment 15000.0 -179000.0 -4.8 29280.0 -170000.0 -4.59 -6.6403 -0.9998 3554671 ACon1_001234 COC(=O)C1=C2C(Oc3cc(CO)cc(O)c3C2=O)C(O)C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N23 compound treatment 186800.0 -7600.0 -0.2 179840.0 -19100.0 -0.52 -0.5087 -0.9171 3558632 ACon1_001235 C/C=C(\C)/C(=O)OC(C)(C)C1Cc2cc3ccc(=O)oc3cc2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 N24 compound treatment 274000.0 79600.0 2.13 201920.0 3020.0 0.08 1.5633 0.7337 3559148 ACon1_001236 OCC1OC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)C(O[C@H]5OC[C@](O)(CO)[C@H]5O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O01 compound treatment 212520.0 18100.0 0.48 157040.0 -41900.0 -1.13 -0.4587 -0.3721 3559908 ACon1_001237 CC1(CO)Oc2cc(O)c3c(=O)c(coc3c2C=C1)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O02 compound treatment 183920.0 -10500.0 -0.28 237800.0 38900.0 1.05 0.5464 0.5014 3558779 ACon1_001238 C[C@H](C[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O03 compound treatment 181760.0 -12600.0 -0.34 175520.0 -23400.0 -0.63 -0.6867 -0.9569 3553208 ACon1_001239 CC(=O)c1cc(C)c(O)c(COC2OC(CO)C(O)C(O)C2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O04 compound treatment 203040.0 8640.0 0.23 230240.0 31300.0 0.85 0.7633 0.868 3558817 ACon1_001240 C[C@@H]1O[C@@H](O[C@@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@]2(C)CO)[C@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O05 compound treatment 178840.0 -15600.0 -0.42 160480.0 -38400.0 -1.04 -1.0298 -0.9192 3558838 ACon1_001241 COc1cc(CCC(O)CC(=O)CCc2ccccc2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O06 compound treatment 24520.0 -170000.0 -4.54 23920.0 -175000.0 -4.74 -6.5629 -0.9998 3558830 ACon1_001242 CC(=O)OC1/C=C(/CCC=C(C)C(=O)C=CC1(C)C)\C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O07 compound treatment 167520.0 -26900.0 -0.72 166760.0 -32100.0 -0.87 -1.1237 -0.9955 3554193 ACon1_001243 CCC[C@H]1C[C@H]2OC(=O)c3c(O)c(OC)c(OC)cc3[C@H]2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O08 compound treatment 162360.0 -32000.0 -0.86 174680.0 -24200.0 -0.66 -1.0697 -0.9913 3558870 ACon1_001244 CC(=O)CCCCCCCc1cc(=O)c2ccccc2[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O09 compound treatment 209320.0 14900.0 0.4 188160.0 -10700.0 -0.29 0.0766 0.1551 3614735 ACon1_001245 OC[C@H]1O[C@@H](Oc2ccc(/C=C/c3cc(O)cc(O)c3)cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O10 compound treatment 183840.0 -10600.0 -0.28 191160.0 -7740.0 -0.21 -0.3479 -0.9892 3558880 ACon1_001246 CC1OC(OC2C(O)C(O)C(OC2Oc3cc(O)c4c(=O)cc(oc4c3)c5ccc(O)c(O)c5)C(=O)O)C(O)C(O)C1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O11 mock treatment 175560.0 -18800.0 -0.5 181160.0 -17700.0 -0.48 -0.696 -0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O12 mock treatment 184760.0 -9640.0 -0.26 188040.0 -10900.0 -0.29 -0.3903 -0.9979 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O13 compound treatment 153600.0 -40800.0 -1.09 142920.0 -56000.0 -1.52 -1.8434 -0.987 3558794 ACon1_001247 CCCCCCCCCCCC(O)CC(=O)OCC(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O14 compound treatment 178920.0 -15500.0 -0.41 182120.0 -16800.0 -0.45 -0.6141 -0.9989 3555946 ACon1_001248 OC1CCC(O)(C(=O)O)C1(O)C(=O)OCc2cc(O)ccc2OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O15 compound treatment 188280.0 -6120.0 -0.16 190160.0 -8740.0 -0.24 -0.2831 -0.9839 3558871 ACon1_001249 CC(=O)c1c(O)cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O16 compound treatment 12960.0 -181000.0 -4.85 13280.0 -186000.0 -5.03 -6.9852 -0.9998 3558697 ACon1_001250 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)/C(=C/C)/C)C1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O17 compound treatment 194920.0 517.0 0.01 227600.0 28700.0 0.78 0.5592 0.7196 3558900 ACon1_001251 CCC(C)C(=O)OCC1(CO1)c2ccc(C)cc2OC(=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O18 compound treatment 194640.0 237.0 0.01 219480.0 20600.0 0.56 0.3985 0.7151 3557674 ACon1_001252 OC1COC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O19 compound treatment 198720.0 4320.0 0.12 192040.0 -6860.0 -0.19 -0.0497 -0.2271 3558944 ACon1_001253 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O20 compound treatment 203600.0 9200.0 0.25 204160.0 5260.0 0.14 0.2747 0.9662 3559017 ACon1_001254 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O21 compound treatment 192880.0 -1520.0 -0.04 198680.0 -220.0 -0.01 -0.033 -0.8019 3555821 ACon1_001255 OC(=O)C(CCCCCCOC(=O)C(=O)OCCCCCCC(C(=O)O)C(=C)C(=O)O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O22 compound treatment 10480.0 -184000.0 -4.92 11880.0 -187000.0 -5.06 -7.0589 -0.9999 3559011 ACon1_001256 CCCCCCCCCC/C=C\CCCCCCCc1cccc(O)c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O23 compound treatment 214200.0 19800.0 0.53 206520.0 7620.0 0.21 0.5203 0.9156 3558726 ACon1_001257 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2c3c(O)cc(O)c4c(=O)cc(oc34)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 O24 compound treatment 232000.0 37600.0 1.01 197680.0 -1220.0 -0.03 0.6878 0.6835 3557891 ACon1_001258 OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)CC(Oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P01 compound treatment 192680.0 -1720.0 -0.05 180320.0 -18600.0 -0.5 -0.3883 -0.7687 1104287 ACon1_001259 CCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P02 compound treatment 62200.0 -132000.0 -3.54 66240.0 -133000.0 -3.59 -5.04 -1.0 3559023 ACon1_001260 CC(=C)C(=O)OC1CC(CO)CCC/C(=C/C2OC(=O)C(=C)C21)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P03 compound treatment 201680.0 7280.0 0.19 197680.0 -1220.0 -0.03 0.1143 0.5789 3558101 ACon1_001261 COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P04 compound treatment 191440.0 -2960.0 -0.08 211800.0 12900.0 0.35 0.1909 0.5331 3554885 ACon1_001262 COc1cc(ccc1O)C2Oc3c(C2CO)c(ccc3O)[C@@H]4Oc5cc(O)cc(O)c5C(=O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P05 compound treatment 184760.0 -9640.0 -0.26 202520.0 3620.0 0.1 -0.1131 -0.4098 1034727 ACon1_001263 COc1ccc(cc1)c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P06 compound treatment 179360.0 -15000.0 -0.4 175680.0 -23200.0 -0.63 -0.729 -0.9768 3559423 ACon1_001264 OCC(Cc1ccc2OCOc2c1)C(CO)Cc3ccc4OCOc4c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P07 compound treatment 188000.0 -6400.0 -0.17 179880.0 -19000.0 -0.51 -0.4852 -0.8941 1096015 ACon1_001265 CC12CC(O)CC(C)(C)C2=CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P08 compound treatment 169720.0 -24700.0 -0.66 186400.0 -12500.0 -0.34 -0.7061 -0.9518 1115322 ACon1_001266 COc1ccn(C)c(=O)c1C#N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P09 compound treatment 195120.0 717.0 0.02 203680.0 4780.0 0.13 0.1051 0.8032 3558968 ACon1_001267 O[C@@H]1Cc2c(O)cc3O[C@]4(Oc5cc(O)cc(O)c5[C@H]([C@H]4O)c3c2O[C@@H]1c6ccc(O)c(O)c6)c7ccc(O)cc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P10 compound treatment 19640.0 -175000.0 -4.67 17840.0 -181000.0 -4.9 -6.7716 -0.9997 288 ACon1_001268 C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P11 mock treatment 181680.0 -12700.0 -0.34 182520.0 -16400.0 -0.44 -0.5542 -0.9915 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P12 mock treatment 216320.0 21900.0 0.59 189680.0 -9220.0 -0.25 0.2381 0.3736 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P13 compound treatment 146120.0 -48300.0 -1.29 150480.0 -48400.0 -1.31 -1.8401 -1.0 3558980 ACon1_001269 C/C(=C\C(=O)O)/CCC1C(=C)CCC2C(C)(CO)CCCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P14 compound treatment 8800.0 -186000.0 -4.96 8920.0 -190000.0 -5.14 -7.1473 -0.9998 3558996 ACon1_001270 CCCCCCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P15 compound treatment 8800.0 -186000.0 -4.96 9480.0 -189000.0 -5.13 -7.1366 -0.9999 3555936 ACon1_001271 Oc1ccc(/C=C/c2cc3O[C@H]([C@@H](c3c(O)c2)c4cc5O[C@@H]([C@H](c5c(O)c4)c6cc(O)cc(O)c6)c7ccc(O)c(O)c7)c8ccc(O)cc8)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P16 compound treatment 200200.0 5800.0 0.16 201320.0 2420.0 0.07 0.156 0.9266 3559197 ACon1_001272 CO/C(=C\1/OC(=O)C=C1OC)/[C@@H]2O[C@H]2c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P17 compound treatment 186160.0 -8240.0 -0.22 208200.0 9300.0 0.25 0.0221 0.0661 3559114 ACon1_001273 COc1ccc(cc1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc5OCOc5c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P18 compound treatment 209680.0 15300.0 0.41 193080.0 -5820.0 -0.16 0.1776 0.4054 1025510 ACon1_001274 COc1ccc(cc1OC)C2OCC3(O)C(OCC23)c4ccc(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P19 compound treatment 12200.0 -182000.0 -4.87 11640.0 -187000.0 -5.07 -7.031 -0.9998 2141039 ACon1_001275 CO[C@H]1C[C@H](O[C@H]2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P20 compound treatment 210680.0 16300.0 0.44 184840.0 -14100.0 -0.38 0.0387 0.067 3552212 ACon1_001276 C[C@@H]([C@@H]1CC[C@@](C)(O1)C=C)C(=O)CC=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P21 compound treatment 13160.0 -181000.0 -4.85 28520.0 -170000.0 -4.61 -6.6897 -0.9997 3552101 ACon1_001277 C/C=C/C=C/C=C/C(=O)O[C@@H]1C=C2COC(=O)[C@]2(O)[C@@]3(C)CCCC(C)(C)[C@H]13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P22 compound treatment 150400.0 -44000.0 -1.18 143360.0 -55500.0 -1.5 -1.8955 -0.9927 3558924 ACon1_001278 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P23 compound treatment 256480.0 62100.0 1.66 216000.0 17100.0 0.46 1.5015 0.871 3557752 ACon1_001279 OCC1OC(Oc2cc(O)c3C(=O)C(O)C(Oc3c2)c4ccc(O)cc4)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2293 P24 compound treatment 253240.0 58800.0 1.57 222480.0 23600.0 0.64 1.5643 0.921 1102176 ACon1_001280 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C=CC3(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A01 compound treatment 18320.0 -166000.0 -4.44 15720.0 -167000.0 -4.53 -6.3386 -0.9999 3555976 ACon1_001281 ON1CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A02 compound treatment 251480.0 67300.0 1.8 219360.0 36400.0 0.99 1.9698 0.9597 3557285 ACon1_001282 COC(=O)[C@]12Oc3cc(C)c(c(O)c3C(=O)C2=C(O)CC[C@@H]1O)c4ccc(O)c5C(=O)C6=C(O)C[C@H](C)[C@H](OC(=O)C)[C@@]6(Oc45)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A03 compound treatment 9520.0 -175000.0 -4.67 9760.0 -173000.0 -4.69 -6.6191 -1.0 3554124 ACon1_001283 CCC(C)[C@@H]1N(C)C(=O)[C@H](OC(=O)[C@H](C(C)CC)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)CC)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A04 compound treatment 204640.0 20500.0 0.55 172960.0 -10000.0 -0.27 0.1956 0.3201 3558541 ACon1_001284 OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC=C3[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A05 compound treatment 118480.0 -65700.0 -1.76 129200.0 -53800.0 -1.46 -2.2717 -0.9956 3559091 ACon1_001285 OC1[C@H](OC(=O)c2cc(O)c(O)c(O)c2)OC3COC(=O)c4cc(O)c(O)c(O)c4-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]1[C@@H]3OC(=O)c6cc(O)c(O)c(O)c6c7c(O)c(O)c(O)cc7C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A06 compound treatment 121640.0 -62500.0 -1.67 133000.0 -50000.0 -1.35 -2.1392 -0.9945 3559109 ACon1_001286 COc1c(O)c(O)cc2ccc3cccc(O)c3c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A07 compound treatment 228480.0 44300.0 1.19 190440.0 7470.0 0.2 0.9812 0.8159 3557604 ACon1_001287 COc1cc(O[C@@H]2O[C@H](COC3OCC(O)C(O)C3O)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A08 compound treatment 214160.0 30000.0 0.8 181960.0 -1010.0 -0.03 0.548 0.6825 3559066 ACon1_001288 OC[C@H]1O[C@@H](Oc2ccc(COC(=O)CC(O)(CC(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3)C(=O)OCc5ccc(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)cc5)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A09 compound treatment 243640.0 59500.0 1.59 173280.0 -9690.0 -0.26 0.9394 0.5826 3559055 ACon1_001289 C[C@@H]1O[C@@H](O[C@@H]2C=C(CO)[C@@H]3[C@H]2C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H](O)[C@H]1OC(=O)/C=C/c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A10 compound treatment 10560.0 -174000.0 -4.64 11760.0 -171000.0 -4.64 -6.5611 -1.0 3559247 ACon1_001290 COc1c(C)c(O)c(C)c(O)c1C(=O)CCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A11 compound treatment 206800.0 22600.0 0.61 195160.0 12200.0 0.33 0.6614 0.9592 3552701 ACon1_001291 C[C@@H]1CC[C@]2(C)[C@@]3(C)CC[C@@]2(OC3=O)[C@]41C[C@@H](OC4=O)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A12 compound treatment 216440.0 32300.0 0.86 188480.0 5510.0 0.15 0.7159 0.8171 3559273 ACon1_001292 COC(=O)[C@H](OC(=O)C)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CC[C@@H](C3=C)[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A13 mock treatment 209400.0 25200.0 0.68 183840.0 866.0 0.02 0.4939 0.7312 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A14 mock treatment 217120.0 33000.0 0.88 219120.0 36100.0 0.98 1.3153 0.9986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A15 compound treatment 201360.0 17200.0 0.46 176480.0 -6490.0 -0.18 0.201 0.4081 2097145 ACon1_001293 COc1c(ccc2Oc3c(O)cc(C)cc3COC(=O)c12)C(CC(C)C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A16 compound treatment 10360.0 -174000.0 -4.65 11960.0 -171000.0 -4.63 -6.5611 -1.0 3559137 ACon1_001294 O=C(CCc1ccccc1)/C=C/CCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A17 compound treatment 221600.0 37400.0 1.0 184320.0 1350.0 0.04 0.7339 0.7323 3552685 ACon1_001295 C[C@@H]1CC(=O)C2=C(C1)C[C@@H](O)[C@]3(O)[C@@H](O)c4c(O)cccc4C(=O)C23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A18 compound treatment 152240.0 -31900.0 -0.85 180640.0 -2330.0 -0.06 -0.6485 -0.7574 3559173 ACon1_001296 COc1cc(OC)c(cc1OC)C(O)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A19 compound treatment 241960.0 57800.0 1.55 192520.0 9550.0 0.26 1.2759 0.814 3189183 ACon1_001297 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]3NC(=N)N)O[C@@H](C)[C@]2(O)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A20 compound treatment 246200.0 62000.0 1.66 182360.0 -614.0 -0.02 1.1616 0.7 3559107 ACon1_001298 CC1(C)[C@H](O)[C@H](O)C[C@]2(C)[C@H]3CCC(C)(C=C3CCC12)C(=O)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A21 compound treatment 250080.0 65900.0 1.76 212960.0 30000.0 0.81 1.8208 0.938 3557672 ACon1_001299 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4cc(O)c(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A22 compound treatment 262000.0 77800.0 2.08 190680.0 7710.0 0.21 1.6198 0.7741 3559201 ACon1_001300 COc1cc(cc(OC)c1OC)C2OCC3C(OCC23)c4cc(OC)c(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A23 compound treatment 210800.0 26600.0 0.71 191480.0 8510.0 0.23 0.6667 0.8903 2089505 ACon1_001301 Cc1cc(O)cc2oc(=O)c3c(O)cc(O)cc3c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 A24 compound treatment 215960.0 31800.0 0.85 181120.0 -1850.0 -0.05 0.5659 0.6642 3557367 ACon1_001302 CC(=O)O[C@@H]1C[C@@]2(C)[C@]3(CO3)[C@@H]1O[C@@H]4C=C(C)C(O)C[C@@]42C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B01 compound treatment 256000.0 71800.0 1.92 206400.0 23400.0 0.63 1.8072 0.8931 3553926 ACon1_001303 CC1=CC(=O)[C@H]2C(C)(C)CCC[C@]2(C)[C@@]1(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B02 compound treatment 9760.0 -174000.0 -4.67 9560.0 -173000.0 -4.69 -6.6184 -1.0 3614774 ACon1_001304 CCCC(O)c1c(O)cccc1C(=O)CC(O)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B03 compound treatment 195480.0 11300.0 0.3 207040.0 24100.0 0.65 0.6748 0.9392 3553162 ACon1_001305 C[C@H]1OC(=O)c2c(O)c(C(=O)O)c(O)c(C)c2[C@@H]1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B04 compound treatment 113720.0 -70400.0 -1.88 135800.0 -47200.0 -1.28 -2.2354 -0.9821 3614776 ACon1_001306 COc1ccc(/C=C/c2cc(OC)cc3OC(C)(C)CCc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B05 compound treatment 11440.0 -173000.0 -4.62 13360.0 -170000.0 -4.59 -6.5139 -1.0 3614779 ACon1_001307 C/C=C(/C)\C(=O)O[C@H]1[C@H](OC(=O)/C(=C\C)/C)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(OC7OC(C)C(O)C(OC8OC(CO)C(O)C(O)C8O)C7O)C6O)C(=O)O)C(C)(C)C5CC[C@]43C)[C@@H]2CC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B06 compound treatment 198600.0 14400.0 0.39 230120.0 47100.0 1.28 1.1756 0.8816 1032451 ACon1_001308 CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B07 compound treatment 170480.0 -13700.0 -0.37 200880.0 17900.0 0.48 0.084 0.1383 3614784 ACon1_001309 CC(C)C1=C(O)C(=O)C2=C([C@@H](CC3C(C)(C)CCC[C@@]32CO)OC(=O)C)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B08 compound treatment 187080.0 2920.0 0.08 215200.0 32200.0 0.87 0.6721 0.7673 3614787 ACon1_001310 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]([C@H](C)OC(=O)C)[C@@H]1CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B09 compound treatment 192720.0 8560.0 0.23 185920.0 2950.0 0.08 0.2183 0.9004 3614791 ACon1_001311 CCC(C)CCC(O)C1=C(C)C(O)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B10 compound treatment 14840.0 -169000.0 -4.53 20960.0 -162000.0 -4.39 -6.3041 -0.9999 3554503 ACon1_001312 CO[C@@H]1[C@@H](O)[C@H](C)O[C@@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)[C@@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B11 compound treatment 184840.0 678.0 0.02 195760.0 12800.0 0.35 0.2576 0.7431 3614794 ACon1_001313 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B12 compound treatment 183760.0 -403.0 -0.01 198400.0 15400.0 0.42 0.2877 0.6886 3614796 ACon1_001314 COc1c(C)c(OC/C=C(\C)/C(=O)OCC(O)C(O)C(O)C(O)CO)cc(CO)c1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B13 mock treatment 180600.0 -3560.0 -0.1 181200.0 -1770.0 -0.05 -0.1013 -0.9497 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B14 mock treatment 178280.0 -5880.0 -0.16 174720.0 -8250.0 -0.22 -0.2693 -0.9853 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B15 compound treatment 16280.0 -168000.0 -4.49 21240.0 -162000.0 -4.38 -6.2715 -0.9999 3614799 ACon1_001315 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(CO)[C@@H](CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B16 compound treatment 179960.0 -4200.0 -0.11 200520.0 17500.0 0.48 0.2564 0.5253 3614803 ACon1_001316 CCN1C[C@]2(C)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@@](C[C@@H]5OC)(OC)C6[C@@H](O)C32)[C@@H]61 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B17 compound treatment 12600.0 -172000.0 -4.59 14160.0 -169000.0 -4.57 -6.4766 -1.0 3614807 ACon1_001317 COc1cc(c(OC)c2oc3cc(O)c(O)cc3c12)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B18 compound treatment 176720.0 -7440.0 -0.2 189840.0 6870.0 0.19 -0.0093 -0.0343 3614809 ACon1_001318 COc1ccc2nccc(C(O)C3CC4CC[N+]3([O-])CC4C=C)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B19 compound treatment 220640.0 36500.0 0.98 204920.0 21900.0 0.59 1.1101 0.9717 3614812 ACon1_001319 CC1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(CCC6(CCC54C)C(=O)OC7OC(CO)C(O)C(O)C7O)C(=O)O)C2(C)CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B20 compound treatment 224600.0 40400.0 1.08 193920.0 10900.0 0.3 0.9744 0.8688 3614813 ACon1_001320 CCN1C[C@]2(COC)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](OC)[C@@H]4[C@](O)(C[C@@H]5OC)[C@]6(O)CC32)[C@H]16 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B21 compound treatment 15200.0 -169000.0 -4.52 13600.0 -169000.0 -4.59 -6.4382 -1.0 3558920 ACon1_001321 Oc1cc(cc(O)c1O)C(=O)O[C@@H]2O[C@@H]3COC(=O)c4cc(O)c(O)c(O)c4-c5c(O)c(O)c(O)cc5C(=O)O[C@H]3[C@H](OC(=O)c6cc(O)c(O)c(O)c6)[C@H]2OC(=O)c7cc(O)c(O)c(O)c7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B22 compound treatment 219880.0 35700.0 0.96 195640.0 12700.0 0.34 0.918 0.9044 1099690 ACon1_001322 COC(=O)C12CC3CC(C(C)O)C2N(C3)CCc4c1[nH]c5ccc(OC)cc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B23 compound treatment 209280.0 25100.0 0.67 187200.0 4230.0 0.11 0.556 0.8158 3614819 ACon1_001323 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O[C@@H]7OC[C@H](O)[C@H](O)[C@H]7O)[C@H]6O)C(=O)O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]8OC[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 B24 compound treatment 241360.0 57200.0 1.53 222000.0 39000.0 1.06 1.8289 0.9837 3614822 ACon1_001324 COc1cc2CCN(C)C3(Cc4ccc5OCOc5c4C3O)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C01 compound treatment 11480.0 -173000.0 -4.62 17520.0 -165000.0 -4.48 -6.4335 -0.9999 3180147 ACon1_001325 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(O)c(OC)cc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C02 compound treatment 10360.0 -174000.0 -4.65 12200.0 -171000.0 -4.62 -6.5565 -1.0 3558915 ACon1_001326 Oc1ccc(cc1)C2Oc3cc(O)cc(O)c3C(=O)C2C4C(Oc5cc(O)cc(O)c5C4=O)c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C03 compound treatment 189320.0 5160.0 0.14 203200.0 20200.0 0.55 0.4847 0.8584 3559041 ACon1_001327 COc1ccc(/C=C/C(=O)O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C04 compound treatment 163600.0 -20600.0 -0.55 184880.0 1910.0 0.05 -0.3524 -0.638 3559084 ACon1_001328 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c(C(=O)c3ccc(O)cc3)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C05 compound treatment 186600.0 2440.0 0.07 207280.0 24300.0 0.66 0.5114 0.7734 3554661 ACon1_001329 COC(=O)C1(Cc2ccc(O)cc2)OC(=O)C(=C1c3ccc(O)cc3)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C06 compound treatment 190320.0 6160.0 0.16 187160.0 4190.0 0.11 0.1966 0.9833 3558716 ACon1_001330 COc1cc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)ccc1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C07 compound treatment 144600.0 -39600.0 -1.06 207000.0 24000.0 0.65 -0.2884 -0.2321 3552084 ACon1_001331 C/C=C/C=C/C(=O)N1CC[C@]23[C@@H]1N4CC[C@]3([C@H]5Nc6ccccc62)c7c(cccc7[C@@H]4C8OC8(C)C)N5C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C08 compound treatment 204640.0 20500.0 0.55 223480.0 40500.0 1.1 1.1627 0.9486 3559229 ACon1_001332 OC[C@H]1O[C@@H](Oc2ccc(cc2)c3cc(=O)c4c(O)cc(O)cc4o3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C09 compound treatment 168880.0 -15300.0 -0.41 203480.0 20500.0 0.56 0.1035 0.1501 3559102 ACon1_001333 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C3(C)C)O[C@@H]([C@H]2O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C10 compound treatment 160880.0 -23300.0 -0.62 181800.0 -1170.0 -0.03 -0.4628 -0.7422 3559180 ACon1_001334 C[C@@H]1O[C@@H](O[C@H]2[C@@H](O)[C@@H](C)O[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5C=CC7=C8CC(C)(C)CC[C@]8(CO)CC[C@]76C)[C@]4(C)CO)O[C@@H]3CO)[C@@H]2O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C11 mock treatment 178880.0 -5280.0 -0.14 175560.0 -7410.0 -0.2 -0.2418 -0.9852 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C12 mock treatment 182600.0 -1560.0 -0.04 180360.0 -2610.0 -0.07 -0.0796 -0.9684 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C13 compound treatment 195640.0 11500.0 0.31 179880.0 -3090.0 -0.08 0.1579 0.496 3558601 ACon1_001335 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)OC6OCC(OC7OCC(O)C(O)C7O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C14 compound treatment 191960.0 7800.0 0.21 190040.0 7070.0 0.19 0.2827 0.9991 3557383 ACon1_001336 CO[C@H]1C(O[C@@H]2C[C@H]3O[C@@H]([C@@H](O)[C@H](OC(=O)/C(=C/C)/CO)[C@]3(O)O[C@H]12)C(=O)OC)n4cnc5c(N)ncnc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C15 mock treatment 206160.0 22000.0 0.59 174160.0 -8810.0 -0.24 0.2473 0.3895 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C16 mock treatment 167040.0 -17100.0 -0.46 165560.0 -17400.0 -0.47 -0.6572 -0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C17 compound treatment 94000.0 -90200.0 -2.41 119080.0 -63900.0 -1.73 -2.9285 -0.9867 3555977 ACon1_001337 ON1CCCCCNC(=O)CCC(=O)N(O)CCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C18 compound treatment 206040.0 21900.0 0.59 176040.0 -6930.0 -0.19 0.2811 0.4573 3559187 ACon1_001338 CC(C)C[C@@](O)(CC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C19 compound treatment 172200.0 -12000.0 -0.32 162520.0 -20500.0 -0.55 -0.6178 -0.966 3614831 ACon1_001339 C[C@H]1O[C@@H](OC/2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(=O)O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)/C=C/C=C/CC\C=C\C=C\C=C\C=C2)[C@@H](O)[C@@H](N)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C20 compound treatment 211640.0 27500.0 0.73 178360.0 -4610.0 -0.12 0.4314 0.5786 3559183 ACon1_001340 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(=O)O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C21 compound treatment 13760.0 -170000.0 -4.56 13560.0 -169000.0 -4.59 -6.4662 -1.0 3558289 ACon1_001341 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)O[C@@]%101CCC(C)CO%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C22 compound treatment 188480.0 4320.0 0.12 181920.0 -1050.0 -0.03 0.0615 0.5168 3559203 ACon1_001342 C[C@H]1[C@@H]2CC[C@]3(C)O[C@]4(C)C(O)[C@@H]5[C@H]6[C@H](C(=C7[C@@H]6C[C@@](C)(O)C[C@H]8[C@H](C)C(=O)O[C@@H]87)C)C4(C53)[C@H]2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C23 compound treatment 130680.0 -53500.0 -1.43 162600.0 -20400.0 -0.55 -1.4016 -0.9141 3554240 ACon1_001343 CCCCC/C=C\C/C=C\C(O)CCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 C24 compound treatment 183480.0 -683.0 -0.02 166720.0 -16300.0 -0.44 -0.3241 -0.7358 3555026 ACon1_001344 COc1cc2[C@@H]3CCN4CC=C[C@]56CC[C@H]3[C@]64N(C(=O)C5)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D01 compound treatment 231800.0 47600.0 1.27 214800.0 31800.0 0.86 1.5103 0.9818 3553596 ACon1_001345 CC(C)C1NC(=O)/C(=C/c2c[nH]cn2)/NC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D02 compound treatment 177800.0 -6360.0 -0.17 167080.0 -15900.0 -0.43 -0.4246 -0.9176 3614835 ACon1_001346 OCc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D03 compound treatment 217960.0 33800.0 0.9 250080.0 67100.0 1.82 1.9239 0.9481 3559559 ACon1_001347 C[C@@H]1C2[C@@H](CC(C)C(=O)C/C=C(\C)/C[C@@H]2O)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D04 compound treatment 43360.0 -141000.0 -3.77 167160.0 -15800.0 -0.43 -2.9659 -0.7824 3614837 ACon1_001348 C[C@H]1C2[C@H](CC3C4CC=C5C[C@@H](O)C[C@@H](O[C@@H]6OC[C@H](O)[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]8OC(=O)C)[C@]5(C)C4CC[C@]23C)O[C@]91OCC(=C)[C@H](OC%10OC(C)C(O)C(O)C%10O)[C@@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D05 compound treatment 212360.0 28200.0 0.75 231440.0 48500.0 1.31 1.4611 0.9654 3614840 ACon1_001349 OCc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D06 compound treatment 228120.0 44000.0 1.18 199800.0 16800.0 0.46 1.1535 0.9148 3614842 ACon1_001350 COc1cc(OC)c(CC=C(C)C)c(/C=C/c2ccc(OC)c(OC)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D07 compound treatment 201560.0 17400.0 0.47 208040.0 25100.0 0.68 0.8089 0.9831 1054271 ACon1_001351 COc1ccc(cc1O)c2cc(=O)c3c(O)c(OC)c(OC)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D08 compound treatment 201560.0 17400.0 0.47 213480.0 30500.0 0.83 0.913 0.9632 3614846 ACon1_001352 CC/C=C/c1ccc(C)cc1\C=C\CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D09 compound treatment 209760.0 25600.0 0.68 229600.0 46600.0 1.26 1.3767 0.9587 3614849 ACon1_001353 OC[C@H]1O[C@@H](OC(=O)/C=C/c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D10 compound treatment 236320.0 52200.0 1.4 229800.0 46800.0 1.27 1.8829 0.9989 3614853 ACon1_001354 CCC(O)C(O)/C=C\C/C=C\CCCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D11 mock treatment 201920.0 17800.0 0.47 252720.0 69700.0 1.89 1.671 0.8582 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D12 mock treatment 213080.0 28900.0 0.77 217400.0 34400.0 0.93 1.206 0.9957 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D13 compound treatment 211320.0 27200.0 0.73 216960.0 34000.0 0.92 1.1643 0.9932 3614858 ACon1_001355 OC(=O)C(Cc1ccc(O)c(O)c1)OC(=O)C2C(C(C2c3ccc(O)c(O)c3)c4ccc(O)c(O)c4)C(=O)OC(Cc5ccc(O)c(O)c5)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D14 compound treatment 223840.0 39700.0 1.06 244880.0 61900.0 1.68 1.9355 0.9757 3614860 ACon1_001356 OC/C=C\1/CN2CC[C@]34[C@@H]2C[C@@H]1[C@@H]5[C@@H]4N(C(=O)CC5O)c6ccccc63 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D15 mock treatment 218920.0 34800.0 0.93 197080.0 14100.0 0.38 0.9274 0.9227 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D16 mock treatment 215480.0 31300.0 0.84 203680.0 20700.0 0.56 0.9887 0.9809 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D17 compound treatment 202280.0 18100.0 0.48 246520.0 63500.0 1.72 1.5591 0.8723 3614863 ACon1_001357 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D18 compound treatment 185440.0 1280.0 0.03 196600.0 13600.0 0.37 0.285 0.7693 1099692 ACon1_001358 CCC1C2N3CCC24C(=C(C1CC3)C(=O)OC)Nc5ccccc54 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D19 compound treatment 111320.0 -72800.0 -1.95 180520.0 -2450.0 -0.07 -1.4247 -0.7308 3614868 ACon1_001359 CCCCCCCCCC(O)C(C)C(O)C(CO)/C=C(\C)/C1=CC(=O)C(C)CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D20 compound treatment 213280.0 29100.0 0.78 224080.0 41100.0 1.11 1.3376 0.9848 3614872 ACon1_001360 CCC1CC2CC3(C1N(CCc4c3[nH]c5ccc(OC)cc45)C2=O)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D21 compound treatment 252360.0 68200.0 1.82 246680.0 63700.0 1.72 2.5094 0.9996 3614874 ACon1_001361 CC(C1CC(O)C(C)(C)O1)C2CC[C@@]3(C)C4CC[C@H]5C(C)C(CC[C@]65C[C@@]46CC[C@]23C)OC7OC(COC(=O)C)C(OC8OC(CO)C(OC9OC(CO)C(O)C(O)C9O)C(OC%10OC(C)C(O)C(O)C%10O)C8O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D22 compound treatment 225480.0 41300.0 1.11 194320.0 11300.0 0.31 0.9987 0.8706 3614877 ACon1_001362 CC(C)C(NC=O)C(=O)N1CCC2Oc3ccc(/C=C\NC(=O)C(Cc4ccccc4)NC(=O)C21)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D23 compound treatment 148800.0 -35400.0 -0.95 173280.0 -9690.0 -0.26 -0.8544 -0.8704 3614881 ACon1_001363 CO[C@H]1[C@H](O)[C@@H](O)[C@H](OC2CC3C(=CC2(C)C=C)CCC4C(C)(C)C(CCC34C)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O)O[C@@H]1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 D24 compound treatment 203920.0 19800.0 0.53 224680.0 41700.0 1.13 1.1721 0.9402 3614885 ACon1_001364 COc1ccc2[nH]c3C4CC/5C(CO)C(Cc3c2c1)[N+]4([O-])C\C5=C\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E01 mock treatment 192360.0 8200.0 0.22 179440.0 -3530.0 -0.1 0.0874 0.3653 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E02 mock treatment 179600.0 -4560.0 -0.12 169400.0 -13600.0 -0.37 -0.3461 -0.8939 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E03 compound treatment 196480.0 12300.0 0.33 186360.0 3390.0 0.09 0.2978 0.8708 3559005 ACon1_001365 CC1OC(O[C@H]2[C@@H](C)O[C@@H](OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O[C@@H]%10O[C@H](CO)[C@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@@](C)(C=O)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](OC%11OC(CO)C(O)C(O)C%11O)[C@H]2O)C(O)C(O)C1OC%12OCC(O)C(O)C%12O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E04 compound treatment 193600.0 9440.0 0.25 201320.0 18300.0 0.5 0.5297 0.9507 3472823 ACon1_001366 COc1ccc(cc1)C(C)C(=O)c2ccc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E05 compound treatment 128160.0 -56000.0 -1.5 153800.0 -29200.0 -0.79 -1.6177 -0.9553 3554702 ACon1_001367 COC(=O)c1cc(O)cc(O)c1C(=O)c2c(O)c(Cl)c(C)c(Cl)c2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E06 compound treatment 169640.0 -14500.0 -0.39 180520.0 -2450.0 -0.07 -0.3217 -0.8162 3559119 ACon1_001368 O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(OC(=O)c4cc(O)c(O)c(O)c4)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E07 compound treatment 152720.0 -31400.0 -0.84 167120.0 -15900.0 -0.43 -0.8982 -0.9513 3558966 ACon1_001369 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E08 compound treatment 71680.0 -112000.0 -3.01 48240.0 -135000.0 -3.65 -4.7068 -0.9954 3559152 ACon1_001370 OC[C@H]1O[C@@H](Oc2ccccc2COC(=O)C3(O)C=CCCC3=O)[C@H](OC(=O)c4ccccc4)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E09 mock treatment 162360.0 -21800.0 -0.58 173200.0 -9770.0 -0.26 -0.5995 -0.9361 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E10 mock treatment 162320.0 -21800.0 -0.58 191000.0 8030.0 0.22 -0.2595 -0.4163 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E11 compound treatment 190960.0 6800.0 0.18 169000.0 -14000.0 -0.38 -0.1389 -0.331 3554750 ACon1_001371 COC1=CC(=O)O[C@@H](CCc2ccc3OCOc3c2)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E12 compound treatment 199440.0 15300.0 0.41 199880.0 16900.0 0.46 0.6126 0.9984 3558916 ACon1_001372 CC1OC(OC2C(O)C(O)C(CO)OC2OC3C(O)C(O)C(OC3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)C[C@@H](O)[C@]8(C)CC[C@]76C)C4(C)C)C(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E13 compound treatment 126520.0 -57600.0 -1.54 122600.0 -60400.0 -1.63 -2.246 -0.9996 3555404 ACon1_001373 CON1c2ccccc2[C@@]3(C=C(O)C(=O)N4/C(=C/c5c[nH]cn5)/C(=O)N[C@]143)C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E14 compound treatment 235760.0 51600.0 1.38 190280.0 7310.0 0.2 1.1158 0.8003 3558010 ACon1_001374 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2OC4OC(CO)C(O)C(O)C4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E15 compound treatment 173360.0 -10800.0 -0.29 176880.0 -6090.0 -0.16 -0.321 -0.9647 3554188 ACon1_001375 CCC(O)CC1CCC(O1)C(C)C(=O)OC(CC)CC2CCC(O2)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E16 compound treatment 71560.0 -113000.0 -3.01 75920.0 -107000.0 -2.9 -4.1791 -0.9998 3557363 ACon1_001376 CC1=CC2OC3[C@H](O)C[C@@](C)([C@@]43CO4)[C@@]2(CO)[C@H](O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E17 mock treatment 167840.0 -16300.0 -0.44 175360.0 -7610.0 -0.21 -0.4545 -0.9413 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E18 mock treatment 192880.0 8720.0 0.23 177200.0 -5770.0 -0.16 0.0543 0.1936 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E19 compound treatment 158600.0 -25600.0 -0.68 177600.0 -5370.0 -0.15 -0.5864 -0.8388 1001646 ACon1_001377 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@@H]3OC(=O)C)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](OC(=O)C)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E20 compound treatment 56720.0 -127000.0 -3.41 51840.0 -131000.0 -3.55 -4.9208 -0.9998 3557369 ACon1_001378 CC1(C[C@@H](O)[C@H]2C3[C@H]1O)C2(C)CCC[C@]3(C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E21 compound treatment 191440.0 7280.0 0.19 223680.0 40700.0 1.1 0.9169 0.8193 3553566 ACon1_001379 CC(C)c1cc2CCC3C(C)(COC(=O)C)C[C@H](O)C[C@]3(C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E22 compound treatment 187840.0 3680.0 0.1 184480.0 1510.0 0.04 0.0984 0.9239 3558597 ACon1_001380 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E23 compound treatment 225200.0 41000.0 1.1 192200.0 9230.0 0.25 0.9528 0.8464 3553861 ACon1_001381 CC1(C)CCC[C@@]2(C)[C@H]1[C@H](O)C=C3COC(=O)[C@@]32O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 E24 compound treatment 190160.0 6000.0 0.16 178800.0 -4170.0 -0.11 0.0335 0.1709 3557439 ACon1_001382 OC(=O)C[C@@H](NCCN[C@H](CC(=O)O)C(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F01 mock treatment 187360.0 3200.0 0.09 208520.0 25500.0 0.69 0.5495 0.7885 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F02 mock treatment 224720.0 40600.0 1.08 229400.0 46400.0 1.26 1.6559 0.9973 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F03 compound treatment 133760.0 -50400.0 -1.35 123400.0 -59600.0 -1.61 -2.0938 -0.996 3559574 ACon1_001383 C[C@H]1CC[C@H](CC2=C(C)C(=O)C[C@@H]12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F04 compound treatment 183560.0 -603.0 -0.02 195400.0 12400.0 0.34 0.2265 0.6725 3614899 ACon1_001384 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)CC3)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F05 compound treatment 15000.0 -169000.0 -4.52 15800.0 -167000.0 -4.53 -6.3998 -1.0 3614903 ACon1_001385 C/C=C(\C)/C(=O)OC1C(OC(=O)\C=C(\C)/CC(=O)O)C2(CO)C(O)CC3(C)C(=CCC4C5(C)CCC(OC6OC(C(O)C(OC7OC(C)C(O)C(OC8OC(CO)C(O)C(O)C8O)C7O)C6O)C(=O)O)C(C)(C)C5CCC43C)C2CC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F06 compound treatment 194000.0 9840.0 0.26 210440.0 27500.0 0.74 0.7119 0.9025 2119735 ACon1_001386 C[N+](C)(C)C(Cc1c[nH]c2ccccc12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F07 compound treatment 162400.0 -21800.0 -0.58 172080.0 -10900.0 -0.29 -0.6202 -0.9503 3614907 ACon1_001387 CCCCCCCC(O)/C=C\C(O)CCC(O)CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F08 compound treatment 195360.0 11200.0 0.3 175120.0 -7850.0 -0.21 0.0614 0.1673 3614911 ACon1_001388 COc1cc(ccc1O)C2OCC3(OC4OC(CO)C(O)C(O)C4O)C(OCC23)c5ccc(O)c(OC)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F09 mock treatment 171640.0 -12500.0 -0.33 172960.0 -10000.0 -0.27 -0.4286 -0.9945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F10 mock treatment 166560.0 -17600.0 -0.47 174400.0 -8570.0 -0.23 -0.4971 -0.9469 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F11 compound treatment 211840.0 27700.0 0.74 228600.0 45600.0 1.24 1.3969 0.97 3614913 ACon1_001389 CC1CC(=O)C2=C(O1)OC3(C)CCC4(O)C(C)(C)CCC(=O)C4(C)C3C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F12 compound treatment 188040.0 3880.0 0.1 164920.0 -18100.0 -0.49 -0.2723 -0.5449 3614916 ACon1_001390 COC(=O)C[C@H]1/C(=C/C)/[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)OC=C1C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F13 compound treatment 172720.0 -11400.0 -0.31 176120.0 -6850.0 -0.19 -0.3476 -0.9712 3614920 ACon1_001391 CC1(C)CCC[C@@]2(C)[C@H]1[C@H](O)C=C(CO)[C@]2(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F14 compound treatment 191480.0 7320.0 0.2 179800.0 -3170.0 -0.09 0.0776 0.3632 3614922 ACon1_001392 OC/C=C\1/CN2CCC3(C2CC1C4=CCC(=O)N5C43)c6ccccc56 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F15 compound treatment 172320.0 -11800.0 -0.32 188720.0 5750.0 0.16 -0.114 -0.323 3614924 ACon1_001393 CC(C)CCCCC(=O)OC1OC(CO)C(O)C2OCC(COC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F16 compound treatment 153760.0 -30400.0 -0.81 143880.0 -39100.0 -1.06 -1.3234 -0.9915 1244529 ACon1_001394 CN1CCc2cc3OCOc3c4-c5ccccc5CC1c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F17 mock treatment 151720.0 -32400.0 -0.87 186160.0 3190.0 0.09 -0.5526 -0.6337 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F18 mock treatment 155240.0 -28900.0 -0.77 177400.0 -5570.0 -0.15 -0.6538 -0.8294 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F19 compound treatment 131320.0 -52800.0 -1.41 133800.0 -49200.0 -1.33 -1.9408 -0.9996 3614927 ACon1_001395 COc1cc-2c(C[C@H]3COC(=O)[C@@H]3Cc4c(OC)c(OC)c(OC)cc42)c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F20 compound treatment 164200.0 -20000.0 -0.53 165560.0 -17400.0 -0.47 -0.7109 -0.9981 3614931 ACon1_001396 CC(=O)N1CCC(CCC(=O)c2ccnc3ccccc23)C(C1)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F21 compound treatment 192840.0 8680.0 0.23 202280.0 19300.0 0.52 0.5337 0.9332 3614932 ACon1_001397 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC3=C[C@@H]4C(=CC[C@H]5[C@]6(C)C[C@@H](O)[C@H]([C@@](C)(OC(=O)C)C(=O)/C=C/C(C)(C)O)[C@@]6(C)CC(=O)[C@]54C)C(C)(C)C3=O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F22 compound treatment 176800.0 -7360.0 -0.2 194800.0 11800.0 0.32 0.0871 0.2318 3614935 ACon1_001398 CCN1C[C@]2(COC)CC[C@H](O)[C@]3(C4C[C@H]5[C@@H](OC(=O)C)C4[C@@](C[C@@H]5OC)(OC(=O)C)C6[C@H](OC)C32)[C@@H]61 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F23 compound treatment 153960.0 -30200.0 -0.81 162000.0 -21000.0 -0.57 -0.9728 -0.9851 3554229 ACon1_001399 CCCc1c(C(=O)O)c(O)cc2C(=O)c3cccc(O)c3C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 F24 compound treatment 218360.0 34200.0 0.91 199960.0 17000.0 0.46 0.972 0.9494 3614940 ACon1_001400 CN1CCc2cc3OCOc3cc2C4OC(O)c5c6OCOc6ccc5C41 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G01 compound treatment 211520.0 27400.0 0.73 210880.0 27900.0 0.76 1.0517 0.9999 3554156 ACon1_001401 CCC(C)C1NC(=O)C(CCC(=O)O)N(C)C(=O)C(C(C)C)N(C)C(=O)CNC(=O)C2CCCN2C(=O)C(Cc3ccccc3)NC(=O)C(OC(=O)C(CCC(=O)O)N(C)C(=O)C(NC(=O)C4CCCCN4C1=O)C(C)C)C(C)CC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G02 compound treatment 164880.0 -19300.0 -0.52 166240.0 -16700.0 -0.45 -0.6851 -0.9979 3558958 ACon1_001402 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2OC(=O)/C=C/c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G03 mock treatment 181240.0 -2920.0 -0.08 162160.0 -20800.0 -0.56 -0.4537 -0.7976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G04 mock treatment 164720.0 -19400.0 -0.52 221560.0 38600.0 1.04 0.3709 0.3179 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G05 compound treatment 176480.0 -7680.0 -0.21 204320.0 21300.0 0.58 0.2633 0.4293 3557320 ACon1_001403 CN/1C(=O)c2ccccc2NC(=O)\C1=C/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G06 compound treatment 182000.0 -2160.0 -0.06 239240.0 56300.0 1.52 1.0362 0.6798 3559121 ACon1_001404 O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(OC(=O)c4cc(O)c(O)c(O)c4)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G07 compound treatment 166560.0 -17600.0 -0.47 152920.0 -30100.0 -0.81 -0.9083 -0.9662 3559035 ACon1_001405 OC[C@@]12O[C@H]2[C@@H](O)[C@@H]3C=CO[C@@H](O[C@@H]4O[C@H](COC(=O)/C=C/c5ccc(O)cc5)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G08 compound treatment 15360.0 -169000.0 -4.52 15840.0 -167000.0 -4.52 -6.3922 -1.0 3559216 ACon1_001406 CC(=CCC/C(=C/Cc1cc(cc(CC=C(C)C)c1O)C(=O)O)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G09 compound treatment 173120.0 -11000.0 -0.3 184600.0 1630.0 0.04 -0.1777 -0.5952 3559155 ACon1_001407 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)C[C@@H](O)[C@@]31O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G10 compound treatment 14640.0 -170000.0 -4.53 16000.0 -167000.0 -4.52 -6.4028 -1.0 1089114 ACon1_001408 COc1cc(O)c(Cc2ccccc2O)c(O)c1C(=O)CCc3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G11 compound treatment 176320.0 -7840.0 -0.21 180280.0 -2690.0 -0.07 -0.1999 -0.9001 3553711 ACon1_001409 CC(CCCc1ccoc1)C2CC=C(CCC=C(C)C)C(=O)O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G12 compound treatment 176080.0 -8080.0 -0.22 154480.0 -28500.0 -0.77 -0.6983 -0.8717 3557253 ACon1_001410 CC(=CCC/C(=C/CC[C@]1(C)Oc2c3CNC(=O)c3cc(O)c2C[C@@H]1O)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G13 compound treatment 173360.0 -10800.0 -0.29 187600.0 4630.0 0.13 -0.1158 -0.3676 3554972 ACon1_001411 COc1cc(O)c(CCO)c2O[C@H](C)CC(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G14 compound treatment 173200.0 -11000.0 -0.29 177080.0 -5890.0 -0.16 -0.3202 -0.9591 3557300 ACon1_001412 CC(O)CC1CCC(O1)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G15 compound treatment 173280.0 -10900.0 -0.29 179720.0 -3250.0 -0.09 -0.2681 -0.8816 3553811 ACon1_001413 CC[C@H](O)C[C@@H]1CC[C@@H](O1)[C@@H](C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G16 compound treatment 185440.0 1280.0 0.03 199880.0 16900.0 0.46 0.3478 0.7578 3558027 ACon1_001414 C[C@@H]1O[C@@H](O[C@@H]2C=C(CO)[C@@H]3[C@H]2C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](OC(=O)/C=C/c5ccc(O)cc5)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G17 compound treatment 149320.0 -34800.0 -0.93 130720.0 -52300.0 -1.41 -1.6593 -0.9795 3553505 ACon1_001415 CC(C)[C@H]1OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C1=O)C(C)C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G18 compound treatment 196840.0 12700.0 0.34 191480.0 8510.0 0.23 0.4026 0.9822 3557922 ACon1_001416 CC(=O)OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G19 mock treatment 166360.0 -17800.0 -0.48 190520.0 7550.0 0.2 -0.1923 -0.3711 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G20 mock treatment 162920.0 -21200.0 -0.57 186920.0 3950.0 0.11 -0.3263 -0.5643 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G21 compound treatment 196480.0 12300.0 0.33 175440.0 -7530.0 -0.2 0.0887 0.229 3552815 ACon1_001417 C[C@]1(C[C@]2(O)O[C@@H]3O1)[C@]4(C[C@@H]2[C@@]34COC(=O)c5ccccc5)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G22 compound treatment 194960.0 10800.0 0.29 217680.0 34700.0 0.94 0.8686 0.8837 1109010 ACon1_001418 COc1cc(cc2OCOc21)C3OCC4C(OCC34)c5cc(OC)c(OC)c(OC)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G23 compound treatment 178240.0 -5920.0 -0.16 181640.0 -1330.0 -0.04 -0.1376 -0.8466 3557629 ACon1_001419 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2OC4OC(CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C(O)C(O)C4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 G24 compound treatment 203360.0 19200.0 0.51 203920.0 20900.0 0.57 0.7641 0.9988 3553937 ACon1_001420 CC1=CC(=O)C2C(C)(C)C(O)CCC2(C)C1(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H01 compound treatment 195360.0 11200.0 0.3 194720.0 11700.0 0.32 0.4366 0.9996 3555028 ACon1_001421 COc1cc2C(O)CCC(=O)c2c(O)c1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H02 compound treatment 13160.0 -171000.0 -4.57 13720.0 -169000.0 -4.58 -6.4744 -1.0 3614951 ACon1_001422 Cc1cc(O)c2C(=O)C3=C(C(O)C(O)C(O)C3O)C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H03 mock treatment 175200.0 -8960.0 -0.24 202560.0 19600.0 0.53 0.2054 0.353 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H04 mock treatment 166120.0 -18000.0 -0.48 189600.0 6630.0 0.18 -0.2144 -0.4165 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H05 compound treatment 19640.0 -165000.0 -4.4 20280.0 -163000.0 -4.4 -6.2263 -1.0 1074963 ACon1_001423 Cc1cc(O)c2C(=O)C3=C(O)C4C(O)C5C6C(O)C(C(=C7C(=O)c8c(O)cc(C)cc8C(=O)C647)O)C53C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H06 compound treatment 182880.0 -1280.0 -0.03 225360.0 42400.0 1.15 0.7871 0.6857 3614955 ACon1_001424 CCCCCC(CC(O)CC(=O)OC(CCCCC)CC(CC(=O)O)OC1OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C(O)C1O)OC3OC(CO)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H07 compound treatment 180080.0 -4080.0 -0.11 175080.0 -7890.0 -0.21 -0.2283 -0.9514 3614956 ACon1_001425 C[C@H]1OC(=O)[C@@]2(C(=C)[C@]3(C)C[C@@H]4C(=C)[C@]5(CC[C@]42C)C=CC(=O)OC5(C)C)[C@@]1(O)C3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H08 compound treatment 194560.0 10400.0 0.28 190920.0 7950.0 0.22 0.3488 0.9919 3614960 ACon1_001426 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H09 compound treatment 26400.0 -158000.0 -4.22 57480.0 -125000.0 -3.4 -5.3863 -0.9942 3614965 ACon1_001427 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](O)[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O)[C@H]1O[C@@H]%10OC[C@@H](O)[C@H](O[C@@H]%11OC[C@H](O)[C@H](O)[C@H]%11O)[C@H]%10O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H10 compound treatment 160200.0 -24000.0 -0.64 186960.0 3990.0 0.11 -0.3769 -0.5799 3614969 ACon1_001428 C[C@H]1OC(=O)CC[C@@H](O)/C=C/[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H11 compound treatment 47960.0 -136000.0 -3.64 53840.0 -129000.0 -3.5 -5.0482 -0.9998 3614972 ACon1_001429 COc1cc(ccc1O)C2OC(c3ccc(O)c(OC)c3)C(C)(O)C2C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H12 compound treatment 182480.0 -1680.0 -0.05 224160.0 41200.0 1.12 0.7566 0.678 3614974 ACon1_001430 C[C@@H]1CCC2C(C)(C)[C@H](OC(=O)C)[C@@H](O)C[C@]2(C)C31Cc4c(O3)c5CN([C@@H](CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H13 compound treatment 19120.0 -165000.0 -4.41 18400.0 -165000.0 -4.46 -6.2721 -1.0 3559258 ACon1_001431 CC1OC(OC2C(O)C(CO)OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)OC8OCC(OC9OCC(O)C(O)C9O)C(O)C8O)C3(C)C)C2O)C(O)C(OC%10OCC(O)(CO)C%10O)C1OC%11OCC(O)(CO)C%11O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H14 compound treatment 166080.0 -18100.0 -0.48 178400.0 -4570.0 -0.12 -0.4296 -0.8604 3614977 ACon1_001432 COc1cc2N3C4C5C(CC3=O)OCC=C6CN(C)CCC4(C(=O)CC56)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H15 compound treatment 209760.0 25600.0 0.68 210640.0 27700.0 0.75 1.0138 0.999 3614978 ACon1_001433 CC1CC(=O)C2=C(O1)OC3(C)CCC4C(C)(C)C(O)CC(O)C4(C)C3C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H16 compound treatment 166800.0 -17400.0 -0.46 193560.0 10600.0 0.29 -0.1258 -0.2304 3614980 ACon1_001434 OC(C1CC2CC[N+]1([O-])CC2C=C)c3ccnc4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H17 compound treatment 184840.0 678.0 0.02 178520.0 -4450.0 -0.12 -0.0725 -0.5942 3614982 ACon1_001435 CC1OC(OC2C(O)C(OC3OC(C)C(OC(=O)C)C(O)C3O)C(CO)OC2OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](OC9OC(CO)C(OC%10OC(CO)C(OC%11OCC(O)C(O)C%11O)C(O)C%10O)C(O)C9O)[C@@](C)(CO)C8CC[C@@]7(C)[C@]6(C)CC4)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H18 compound treatment 161720.0 -22400.0 -0.6 155960.0 -27000.0 -0.73 -0.9416 -0.9952 3614986 ACon1_001436 C=CC1CN(CCC1CCC(=O)c2ccnc3ccccc23)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H19 mock treatment 174760.0 -9400.0 -0.25 183440.0 466.0 0.01 -0.1689 -0.6708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H20 mock treatment 165880.0 -18300.0 -0.49 173280.0 -9690.0 -0.26 -0.5314 -0.9574 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H21 compound treatment 165760.0 -18400.0 -0.49 173600.0 -9370.0 -0.25 -0.5275 -0.9525 3614988 ACon1_001437 OC[C@H]1O[C@@H](Oc2c(O)cccc2COC(=O)C3(O)C4C=CC(C3=O)c5ccc(O)c(O)c45)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H22 compound treatment 161440.0 -22700.0 -0.61 183000.0 25.8 0.0 -0.4293 -0.7063 3614991 ACon1_001438 C=Cc1cncc2c(=O)n3CCc4c([nH]c5ccccc45)-c3cc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H23 compound treatment 154680.0 -29500.0 -0.79 211560.0 28600.0 0.77 -0.0104 -0.0094 3614994 ACon1_001439 CC1OC(O[C@H]2[C@@H](O)C[C@]3(C)C4CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@@]5(C)[C@]4(C)C[C@@H](O)C3[C@]2(C)CO)C(=O)OC7OC(C)C(OC8OCC(OC9OCC(O)C(OC%10OCC(O)C(O)C%10O)C9O)C(O)C8O)C(O)C7O)C(O)C(OC%11OC(CO)C(O)C(O)C%11O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 H24 compound treatment 195640.0 11500.0 0.31 175440.0 -7530.0 -0.2 0.0729 0.1977 3614997 ACon1_001440 CN1Cc2cc3OCOc3cc2CCC(=O)c4cc5OCOc5cc4C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I01 compound treatment 193320.0 9160.0 0.24 197800.0 14800.0 0.4 0.457 0.9719 3552717 ACon1_001441 C[C@@H]1CCC2C(C)(C)[C@H](O)CC[C@]2(C)[C@]31Cc4c(O3)c5CN([C@@H](CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I02 compound treatment 218360.0 34200.0 0.91 246600.0 63600.0 1.72 1.8648 0.9562 3559086 ACon1_001442 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C(O)CC3(C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I03 compound treatment 184760.0 598.0 0.02 184120.0 1150.0 0.03 0.0332 0.9524 3559083 ACon1_001443 OCC1OC(OC2C(O)C(O)C(CO)OC2Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I04 compound treatment 178920.0 -5240.0 -0.14 238400.0 55400.0 1.5 0.9619 0.6382 3559093 ACon1_001444 COc1cc(ccc1O)[C@@H]2[C@@H](CO)[C@](O)(CO)Cc3cc(OC)c(O)cc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I05 mock treatment 164960.0 -19200.0 -0.51 208280.0 25300.0 0.69 0.1212 0.1416 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I06 mock treatment 158920.0 -25200.0 -0.68 207640.0 24700.0 0.67 -0.0053 -0.0055 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I07 compound treatment 14000.0 -170000.0 -4.55 14360.0 -169000.0 -4.56 -6.4463 -1.0 3558957 ACon1_001445 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I08 compound treatment 99080.0 -85100.0 -2.28 85880.0 -97100.0 -2.63 -3.468 -0.9974 3557372 ACon1_001446 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@]54OO[C@@]23C=C5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I09 compound treatment 35200.0 -149000.0 -3.98 42880.0 -140000.0 -3.79 -5.4994 -0.9997 3615002 ACon1_001447 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O)O[C@@]%101CC[C@@](C)(CO[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)O%10 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I10 compound treatment 163120.0 -21000.0 -0.56 207480.0 24500.0 0.66 0.0711 0.0817 3558208 ACon1_001448 COc1cc(/C=C/C(=O)O[C@H]2[C@H](O)[C@@H](C)O[C@H](O[C@@H]3C4O[C@]4(CO)C5C3C=CO[C@H]5O[C@H]6O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]6O)[C@H]2OC(=O)C)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I11 compound treatment 176080.0 -8080.0 -0.22 226960.0 44000.0 1.19 0.6892 0.5694 3553143 ACon1_001449 C[C@H]1CC[C@H]2O[C@]23C(=O)c4occ(C)c4[C@@H](OC(=O)C)[C@]13C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I12 compound treatment 29160.0 -155000.0 -4.15 32680.0 -150000.0 -4.07 -5.8089 -1.0 3557701 ACon1_001450 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I13 compound treatment 183280.0 -883.0 -0.02 188680.0 5710.0 0.15 0.0925 0.5922 3552066 ACon1_001451 C/C=C/C=C/C(=C/1\[C@@H]2[C@@H]([C@@H](C(=O)\C=C\C=C\C)[C@](C)(C1=O)C(=O)C2(C)O)[C@]3(C)OC(=O)C(=C3O)C)/O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I14 compound treatment 194240.0 10100.0 0.27 186600.0 3630.0 0.1 0.26 0.9064 3558037 ACon1_001452 OC[C@H]1O[C@@H](Oc2ccccc2COC(=O)c3c(O)cccc3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I15 compound treatment 173400.0 -10800.0 -0.29 204400.0 21400.0 0.58 0.2066 0.319 3555441 ACon1_001453 CSCC1OC(C(O)C1O)n2cnc3c(=O)[nH]cnc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I16 compound treatment 199360.0 15200.0 0.41 190800.0 7830.0 0.21 0.4373 0.9539 3557495 ACon1_001454 CC1OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)C(O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I17 compound treatment 31120.0 -153000.0 -4.09 14720.0 -168000.0 -4.56 -6.1156 -0.9986 3555348 ACon1_001455 COc1nc(C/C=C(\C)/C\C=C\C(=C\[C@@H](C)[C@@H](O)\C(=C\C)\C)\C)c(C)c(O)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I18 compound treatment 177920.0 -6240.0 -0.17 157560.0 -25400.0 -0.69 -0.6046 -0.8539 3559191 ACon1_001456 CC(C)C[C@@](O)([C@H](O)C(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)C(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I19 compound treatment 180960.0 -3200.0 -0.09 195440.0 12500.0 0.34 0.1781 0.5114 3555032 ACon1_001457 COc1cc2nc3occc3c(OC)c2cc1OCC(OC(=O)C)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I20 compound treatment 175800.0 -8360.0 -0.22 238000.0 55000.0 1.49 0.8952 0.5943 3559208 ACon1_001458 COC(=O)[C@]1(C)CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3(C[C@H]4C(=O)O)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I21 mock treatment 175280.0 -8880.0 -0.24 162600.0 -20400.0 -0.55 -0.558 -0.9292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I22 mock treatment 166800.0 -17400.0 -0.46 239600.0 56600.0 1.53 0.7556 0.4717 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I23 compound treatment 132160.0 -52000.0 -1.39 150960.0 -32000.0 -0.87 -1.5964 -0.9741 3552080 ACon1_001459 C/C=C/C=C/C(=O)c1cc(C)c(O)c(C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 I24 compound treatment 231200.0 47000.0 1.26 208480.0 25500.0 0.69 1.3779 0.9601 3557310 ACon1_001460 CC(O)Cc1cc2c(C)cc(O)cc2c(=O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J01 compound treatment 229840.0 45700.0 1.22 216480.0 33500.0 0.91 1.5054 0.9892 3557337 ACon1_001461 C[C@H](O)CC1=C[C@H](O)[C@@H](C)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J02 compound treatment 50560.0 -134000.0 -3.57 35280.0 -148000.0 -4.0 -5.3543 -0.9984 3553966 ACon1_001462 CC1CC(=O)c2c(C1)ccc3C(O)c4c(O)cccc4C(=O)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J03 compound treatment 186000.0 1840.0 0.05 191560.0 8590.0 0.23 0.1991 0.8381 3559779 ACon1_001463 C[C@H]1[C@@H](O)[C@H](O)C[C@]2(C)CC[C@H](C=C12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J04 compound treatment 231520.0 47400.0 1.27 197880.0 14900.0 0.4 1.1811 0.8884 3615013 ACon1_001464 CC(=O)Cc1cc(O)cc2oc(C)cc(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J05 mock treatment 176680.0 -7480.0 -0.2 200360.0 17400.0 0.47 0.1913 0.374 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J06 mock treatment 181400.0 -2760.0 -0.07 181360.0 -1610.0 -0.04 -0.0832 -0.9686 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J07 compound treatment 194880.0 10700.0 0.29 172640.0 -10300.0 -0.28 0.0049 0.0122 3615015 ACon1_001465 COC(=O)Cc1c(CCC(=O)O)oc2cc(C)cc(O)c2c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J08 compound treatment 121280.0 -62900.0 -1.68 119960.0 -63000.0 -1.71 -2.3957 -1.0 1057044 ACon1_001466 COc1ccc(cc1O)c2oc3cc(O)cc(O)c3c(=O)c2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J09 compound treatment 211160.0 27000.0 0.72 227400.0 44400.0 1.2 1.3611 0.9702 3615018 ACon1_001467 O[C@@H]1CO[C@@H](OC(CCCCc2ccc(O)cc2)CCc3ccc(O)cc3)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J10 compound treatment 204640.0 20500.0 0.55 189720.0 6750.0 0.18 0.5165 0.8945 3615022 ACon1_001468 COC(=O)c1c(C)cc2CC3(Oc2c(C)c1=O)C(C)CCC4C3(C)C=CC(=O)OC4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J11 compound treatment 158200.0 -26000.0 -0.69 129840.0 -53100.0 -1.44 -1.5082 -0.9442 3615023 ACon1_001469 CC1CCC2C(C)(C)CCCC2(C)C1(O)/C=C/C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J12 compound treatment 184200.0 37.5 0.0 179800.0 -3170.0 -0.09 -0.0601 -0.6988 2060335 ACon1_001470 Oc1ccc2C3Oc4cc5OCOc5cc4C3COc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J13 compound treatment 181080.0 -3080.0 -0.08 183880.0 906.0 0.02 -0.041 -0.4762 3615027 ACon1_001471 C[C@H]1[C@H]2OC3=C(C(=O)OC3(C)O)C(=O)[C@]1(C)[C@H]4CCCC[C@]4(O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J14 compound treatment 98360.0 -85800.0 -2.3 93760.0 -89200.0 -2.42 -3.3307 -0.9997 3615031 ACon1_001472 C1Oc2cc3CCNC4Cc5ccccc5-c(c2O1)c43 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J15 compound treatment 213360.0 29200.0 0.78 202080.0 19100.0 0.52 0.918 0.98 3557473 ACon1_001473 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(CO)COP(=O)(O)OCC[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J16 compound treatment 172840.0 -11300.0 -0.3 155200.0 -27800.0 -0.75 -0.7458 -0.9201 1093674 ACon1_001474 COc1ccc(Cc2nccc3cc(O)c(OC)cc23)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J17 compound treatment 168520.0 -15600.0 -0.42 116000.0 -67000.0 -1.81 -1.578 -0.848 3615035 ACon1_001475 CCCCCCCCCC(O)C(C)C(O)C(CO)/C=C(\C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J18 compound treatment 176480.0 -7680.0 -0.21 175400.0 -7570.0 -0.21 -0.2903 -1.0 1014127 ACon1_001476 COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J19 compound treatment 191800.0 7640.0 0.2 191320.0 8350.0 0.23 0.3042 0.9987 3615039 ACon1_001477 COC(=O)c1cc(O)c(O)c(O)c1c2c(O)c(O)c3oc(=O)c4cc(O)c(O)c5oc(=O)c2c3c45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J20 compound treatment 186160.0 2000.0 0.05 177680.0 -5290.0 -0.14 -0.0636 -0.4156 3615041 ACon1_001478 CCC1C2C34CC[N+]2([O-])CCC1C(=C4Nc5c3cccc5OC)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J21 mock treatment 213400.0 29200.0 0.78 170960.0 -12000.0 -0.33 0.323 0.3814 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J22 mock treatment 164200.0 -20000.0 -0.53 165800.0 -17200.0 -0.46 -0.7063 -0.9976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J23 compound treatment 77160.0 -107000.0 -2.86 108720.0 -74300.0 -2.01 -3.4453 -0.9851 3615043 ACon1_001479 CCCC(O)c1c(O)cccc1C/2(O)CC(=O)C\C2=C/C(O)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 J24 compound treatment 135520.0 -48600.0 -1.3 158120.0 -24900.0 -0.67 -1.3958 -0.9529 3615046 ACon1_001480 COC1OC2C(N(C)CCc3cc4OCOc4cc23)c5ccc6OCOc6c15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K01 compound treatment 196320.0 12200.0 0.33 184080.0 1110.0 0.03 0.2511 0.7689 3559758 ACon1_001481 CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K02 compound treatment 200400.0 16200.0 0.43 186520.0 3550.0 0.1 0.375 0.843 3559087 ACon1_001482 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)OC(=O)C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K03 compound treatment 180800.0 -3360.0 -0.09 204760.0 21800.0 0.59 0.3535 0.5924 3559128 ACon1_001483 C[N+](C)(C)C(Cc1ccccc1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K04 compound treatment 179840.0 -4320.0 -0.12 184280.0 1310.0 0.04 -0.0568 -0.4695 3558370 ACon1_001484 CC(=O)OCC1=C[C@H](O)[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K05 compound treatment 174360.0 -9800.0 -0.26 170040.0 -12900.0 -0.35 -0.433 -0.9898 3559003 ACon1_001485 COc1ccc(CC2C(Cc3ccc4OCOc4c3)COC2=O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K06 compound treatment 15400.0 -169000.0 -4.51 14160.0 -169000.0 -4.57 -6.4237 -1.0 3553192 ACon1_001486 CC(=CCc1c(O)cc2oc3c(CC=C(C)C)c(O)c(O)c(CC=C(C)C)c3c(=O)c2c1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K07 mock treatment 169920.0 -14200.0 -0.38 176920.0 -6050.0 -0.16 -0.3853 -0.929 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K08 mock treatment 186240.0 2080.0 0.06 153520.0 -29500.0 -0.8 -0.5246 -0.6562 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K09 compound treatment 36040.0 -148000.0 -3.96 23080.0 -160000.0 -4.33 -5.8625 -0.999 3554961 ACon1_001487 COc1cc(O)c(C(=O)c2c(C)cc(O)cc2OC)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K10 compound treatment 153400.0 -30800.0 -0.82 138840.0 -44100.0 -1.19 -1.4267 -0.9834 3558843 ACon1_001488 COc1cc2c(ccc3cc(OC)c(OC)c(O)c32)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K11 compound treatment 185200.0 1040.0 0.03 160280.0 -22700.0 -0.61 -0.4148 -0.6745 1254 ACon1_001489 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K12 compound treatment 105240.0 -78900.0 -2.11 68600.0 -114000.0 -3.1 -3.6822 -0.9826 3557313 ACon1_001490 C[C@H]1CC[C@@H]2[C@H]([C@@H](C)C=C[C@H]2C1)C(=O)c3c(O)c(c[nH]c3=O)[C@]4(O)CC[C@@H](O)[C@H]5O[C@H]54 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K13 compound treatment 211000.0 26800.0 0.72 224600.0 41600.0 1.13 1.3045 0.9763 3555009 ACon1_001491 COc1cc(OC)c2c(O)c3CO[C@@H](C)[C@@H](O)c3c(c4c5[C@H](O)[C@H](C)OCc5c(O)c6c(OC)cc(OC)cc46)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K14 compound treatment 197000.0 12800.0 0.34 167840.0 -15100.0 -0.41 -0.0469 -0.0877 3559158 ACon1_001492 Cc1ccc2C(=O)c3cc(O[C@@H]4O[C@H](CO[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)ccc3C(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K15 mock treatment 201600.0 17400.0 0.47 184480.0 1510.0 0.04 0.3586 0.766 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K16 mock treatment 180200.0 -3960.0 -0.11 161280.0 -21700.0 -0.59 -0.4902 -0.8214 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K17 compound treatment 195760.0 11600.0 0.31 168640.0 -14300.0 -0.39 -0.055 -0.1108 3552826 ACon1_001493 C[C@]1(CO)CCC[C@@]2(C)C1[C@H](O)CC3=C2COC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K18 compound treatment 168200.0 -16000.0 -0.43 138160.0 -44800.0 -1.21 -1.1598 -0.9017 3559193 ACon1_001494 CC(C)C[C@](CC(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)OCc4ccc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K19 compound treatment 220760.0 36600.0 0.98 194480.0 11500.0 0.31 0.9125 0.8882 3557988 ACon1_001495 OC[C@H]1O[C@@H](Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K20 compound treatment 182800.0 -1360.0 -0.04 207640.0 24700.0 0.67 0.4464 0.6675 3557832 ACon1_001496 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]4OC[C@](O)(CO)[C@H]4O)[C@H]2OC(=O)/C=C/c5ccc(O)c(O)c5)[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K21 compound treatment 186920.0 2760.0 0.07 155800.0 -27200.0 -0.74 -0.468 -0.633 3557515 ACon1_001497 OC[C@@]1(O)CO[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K22 compound treatment 83600.0 -101000.0 -2.69 63880.0 -119000.0 -3.22 -4.1819 -0.9959 3559214 ACon1_001498 CC/C=C\C=C\1/C(CCCCCCCC(=O)O)C=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K23 mock treatment 206960.0 22800.0 0.61 181000.0 -1970.0 -0.05 0.3934 0.6427 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 K24 mock treatment 203680.0 19500.0 0.52 179840.0 -3130.0 -0.08 0.3092 0.5845 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L01 compound treatment 183960.0 -203.0 -0.01 185640.0 2670.0 0.07 0.0472 0.6522 3552939 ACon1_001499 C[C@H](O)c1nc2ccccc2c(=O)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L02 compound treatment 177600.0 -6560.0 -0.18 218600.0 35600.0 0.96 0.5579 0.5691 3615055 ACon1_001500 CC/C=C/c1ccc(C)cc1CCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L03 compound treatment 209520.0 25400.0 0.68 207640.0 24700.0 0.67 0.9518 1.0 3559801 ACon1_001501 C[C@@H]1[C@H]2[C@H](OC1=O)[C@H]3C(=CC(=O)C3=C(C)C[C@@H]2O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L04 compound treatment 15400.0 -169000.0 -4.51 13560.0 -169000.0 -4.59 -6.4351 -1.0 3615060 ACon1_001502 COc1cc(O)c(CC=C(C)C)c(/C=C/c2ccc(OC)c(O)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L05 compound treatment 171080.0 -13100.0 -0.35 174240.0 -8730.0 -0.24 -0.4146 -0.9818 3615064 ACon1_001503 COc1cc(CCC(=O)N2CCC=CC2=O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L06 compound treatment 191120.0 6960.0 0.19 194400.0 11400.0 0.31 0.3503 0.9704 3615066 ACon1_001504 CCCC1=C(/C=C/C(=O)O)C(=O)C(O1)C(C)(C)C2OC(=C(/C=C/C(=O)O)C2=O)CCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L07 mock treatment 194520.0 10400.0 0.28 153280.0 -29700.0 -0.8 -0.3725 -0.4381 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L08 mock treatment 189600.0 5440.0 0.15 182320.0 -654.0 -0.02 0.0903 0.6165 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L09 compound treatment 15040.0 -169000.0 -4.52 13640.0 -169000.0 -4.58 -6.4404 -1.0 2113350 ACon1_001505 COc1cc(CC(C)C(C)Cc2ccc(O)c(OC)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L10 compound treatment 199840.0 15700.0 0.42 181040.0 -1930.0 -0.05 0.2595 0.614 3615071 ACon1_001506 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OC[C@@H]3[C@H](C)[C@H](C[C@H]3C(CO)CO)OC(=O)CC4\C(=C\C)\C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)OC=C4C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L11 compound treatment 15160.0 -169000.0 -4.52 13840.0 -169000.0 -4.58 -6.4343 -1.0 3615072 ACon1_001507 CC1CC(=O)[C@]2(C)CC[C@]3(C)C(=C(O)C(O)C4[C@@]5(C)CC[C@H](O)C(C)(C5CC[C@]43C)C(=O)O)C2C1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L12 compound treatment 205040.0 20900.0 0.56 202400.0 19400.0 0.53 0.7668 0.9995 3557524 ACon1_001508 OC1COC(OCC2OC(OCc3ccccc3)C(O)C(O)C2O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L13 compound treatment 17240.0 -167000.0 -4.46 16640.0 -166000.0 -4.5 -6.3414 -1.0 3615077 ACon1_001509 CC1CCC2C(C)(C)CCCC2(C)C1(O)C/C=C(\CCOC(=O)C)/COC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L14 compound treatment 169680.0 -14500.0 -0.39 212040.0 29100.0 0.79 0.2825 0.3221 3615080 ACon1_001510 CCC(O)CC1CCCC(CC(O)c2ccccc2)N1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L15 mock treatment 200600.0 16400.0 0.44 156720.0 -26300.0 -0.71 -0.1917 -0.2294 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L16 mock treatment 177040.0 -7120.0 -0.19 167920.0 -15100.0 -0.41 -0.4229 -0.94 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L17 compound treatment 181440.0 -2720.0 -0.07 160400.0 -22600.0 -0.61 -0.4836 -0.7858 3615082 ACon1_001511 C[C@H]1CC[C@@H]2N(C1)C[C@H]3[C@@H]4C[C@]5(O[C@@]6(O)[C@H]7C[C@@H](O)[C@H]5[C@]4(O)[C@@H](O)[C@H](O)[C@@H]3[C@]2(C)O)[C@@]7(C)CC[C@@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L18 compound treatment 168880.0 -15300.0 -0.41 147640.0 -35300.0 -0.96 -0.9655 -0.9281 3615084 ACon1_001512 CCN1C[C@]2(C)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@@](C[C@@H]5OC)(OC)C6[C@@H](OC(=O)C)C32)[C@@H]61 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L19 compound treatment 195120.0 11000.0 0.29 160040.0 -22900.0 -0.62 -0.2318 -0.3376 3615086 ACon1_001513 CC(C)C1NC(=O)C(C)NC(=O)CCCNC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)NC(=O)C(NC(=O)C(NC1=O)C(C)c4ccccc4)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L20 compound treatment 165320.0 -18800.0 -0.5 163960.0 -19000.0 -0.51 -0.7204 -0.9999 1050697 ACon1_001514 CC(C)C(O)(C(C)O)C(=O)OCC1=CCN2CCC(O)C21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L21 compound treatment 228240.0 44100.0 1.18 181960.0 -1010.0 -0.03 0.8143 0.6905 3615088 ACon1_001515 C[C@@H]1O[C@@H](O[C@H]2[C@H](C)O[C@@H](OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H]8O)[C@@](C)(CO)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](O[C@@H]%11O[C@@H](CO)[C@H](O)[C@H]%11O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L22 compound treatment 181800.0 -2360.0 -0.06 191320.0 8350.0 0.23 0.1151 0.4905 3615092 ACon1_001516 COc1cc2CCN(C)C3c4c(CC3(O)c2cc1O)ccc5OCOc54 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L23 mock treatment 170840.0 -13300.0 -0.36 194200.0 11200.0 0.3 -0.0371 -0.0792 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 L24 mock treatment 183080.0 -1080.0 -0.03 170320.0 -12700.0 -0.34 -0.2627 -0.7641 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M01 compound treatment 170600.0 -13600.0 -0.36 141160.0 -41800.0 -1.13 -1.057 -0.8892 3553702 ACon1_001517 CC(CCC1(C)C(C)CCC2(CO)C1CCC=C2CO)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M02 compound treatment 202440.0 18300.0 0.49 202920.0 19900.0 0.54 0.7275 0.9988 3559098 ACon1_001518 COc1c(O)cc(cc1O)[C@@H]2Oc3cc(O)cc(O)c3C[C@@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M03 compound treatment 205760.0 21600.0 0.58 167280.0 -15700.0 -0.42 0.1081 0.1507 3559053 ACon1_001519 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]1OC(=O)/C=C/c6ccccc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M04 compound treatment 192280.0 8120.0 0.22 193080.0 10100.0 0.27 0.347 0.9934 3559037 ACon1_001520 COc1cc(ccc1O)C(=O)O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M05 compound treatment 204880.0 20700.0 0.55 165640.0 -17300.0 -0.47 0.06 0.0827 3554112 ACon1_001521 CCC(C)/C=C/C1=CC2=C(Cl)C(=O)C3(C)OC(=O)C(C3C2=CO1)C(=O)C(C)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M06 compound treatment 190120.0 5960.0 0.16 186960.0 3990.0 0.11 0.189 0.982 3559185 ACon1_001522 C[C@]12C[C@H](OC(=O)C2CC[C@]3(C)[C@H]1[C@@H]4OC(=O)[C@@]3(O)C=C4)c5ccoc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M07 compound treatment 184320.0 158.0 0.0 173400.0 -9570.0 -0.26 -0.1803 -0.6955 3559057 ACon1_001523 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@@H]2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M08 compound treatment 147120.0 -37000.0 -0.99 138720.0 -44300.0 -1.2 -1.5478 -0.9955 3557382 ACon1_001524 CC(=O)N(O)CCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M09 mock treatment 169680.0 -14500.0 -0.39 170000.0 -13000.0 -0.35 -0.5223 -0.9988 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M10 mock treatment 184480.0 318.0 0.01 188320.0 5350.0 0.14 0.1083 0.7473 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M11 compound treatment 32080.0 -152000.0 -4.07 32480.0 -150000.0 -4.07 -5.7575 -1.0 3553353 ACon1_001525 CC(=O)OC/1C\C=C(/C)\CC(OC(=O)/C(=C\CO)/C)C2C(OC(=O)C2=C)\C=C1/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M12 compound treatment 181000.0 -3160.0 -0.08 180240.0 -2730.0 -0.07 -0.1122 -0.9978 3558922 ACon1_001526 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@]1(C)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M13 mock treatment 185200.0 1040.0 0.03 202040.0 19100.0 0.52 0.3846 0.7441 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M14 mock treatment 208160.0 24000.0 0.64 197920.0 14900.0 0.4 0.74 0.9752 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M15 compound treatment 180800.0 -3360.0 -0.09 164600.0 -18400.0 -0.5 -0.4153 -0.8216 3554846 ACon1_001527 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(OC)c2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M16 compound treatment 177280.0 -6880.0 -0.18 198120.0 15100.0 0.41 0.1598 0.3554 3558380 ACon1_001528 COc1cc(CCOC2OC(CO)C(OC(=O)/C=C/c3ccc(O)c(OC)c3)C(OC4OC(C)C(O)C(O)C4O)C2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M17 compound treatment 178000.0 -6160.0 -0.16 159240.0 -23700.0 -0.64 -0.5709 -0.8606 3554709 ACon1_001529 COC(=O)c1cc(O)cc(OC)c1Oc2cc(C)cc(O)c2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M18 compound treatment 14400.0 -170000.0 -4.54 14400.0 -169000.0 -4.56 -6.438 -1.0 3557627 ACon1_001530 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O[C@@H]6OC[C@](O)(CO)[C@H]6O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M19 compound treatment 12240.0 -172000.0 -4.6 9440.0 -174000.0 -4.7 -6.5738 -0.9999 3552018 ACon1_001531 C/C=C(/C)\C(=O)O[C@H]1C=C(C)C[C@H](OC(=O)c2ccc(O)cc2)C3[C@@](O)(CC[C@@]31C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M20 compound treatment 24240.0 -160000.0 -4.28 50280.0 -133000.0 -3.59 -5.565 -0.9962 3558024 ACon1_001532 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccc(O)cc6)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M21 compound treatment 185640.0 1480.0 0.04 198240.0 15300.0 0.41 0.3202 0.7712 3553253 ACon1_001533 CC(=O)Cc1cc(=O)c2c(C)cc(O)c(C3OC(CO)C(O)C(O)C3O)c2o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M22 compound treatment 174320.0 -9840.0 -0.26 168560.0 -14400.0 -0.39 -0.4621 -0.9816 3559206 ACon1_001534 CC1(C)C(O)CCC2(C)C3CCC4CC3(CC4(O)CO)CCC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M23 compound treatment 201200.0 17000.0 0.46 221600.0 38600.0 1.05 1.0617 0.9307 3559039 ACon1_001535 COc1cc(/C=C/C(=O)O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 M24 compound treatment 189080.0 4920.0 0.13 185560.0 2590.0 0.07 0.1425 0.9564 3553939 ACon1_001536 CC1=CC(=O)C2C(C)(C)CC(O)CC2(C)C1(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N01 compound treatment 207440.0 23300.0 0.62 223560.0 40600.0 1.1 1.2172 0.9638 1037131 ACon1_001537 Cc1cc(C)c(O)c(c1)C(=O)CC2CC(=O)NC(=O)C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N02 compound treatment 235360.0 51200.0 1.37 210000.0 27000.0 0.73 1.4857 0.9569 3615103 ACon1_001538 CC1CC(O)CC(C)(C)C1(O)/C=C/C(CO)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N03 compound treatment 239760.0 55600.0 1.49 186200.0 3230.0 0.09 1.1133 0.7473 3559788 ACon1_001539 CC(C)[C@@H]1CC[C@@](C)(O)[C@@H]2C[C@H](O)[C@@H]([C@H]21)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N04 compound treatment 197160.0 13000.0 0.35 187440.0 4470.0 0.12 0.3313 0.9001 3615108 ACon1_001540 CC(C)(O)CCC(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4C(C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N05 compound treatment 37880.0 -146000.0 -3.91 22480.0 -160000.0 -4.34 -5.8392 -0.9986 3069522 ACon1_001541 COc1cc(/C=C/C(=O)N2CCC=CC2=O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N06 compound treatment 198560.0 14400.0 0.39 195000.0 12000.0 0.33 0.5025 0.9965 3615112 ACon1_001542 CCCC(O)c1ccc(C)cc1CCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N07 compound treatment 166760.0 -17400.0 -0.47 160160.0 -22800.0 -0.62 -0.7659 -0.9903 3615113 ACon1_001543 Cc1cc(C(=O)Oc2c(C)cc(C(=O)O)c(O)c2C)c(O)c(C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N08 compound treatment 181080.0 -3080.0 -0.08 199560.0 16600.0 0.45 0.2592 0.5678 3559245 ACon1_001544 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2c3c(O)cc4oc(cc(=O)c4c3O)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N09 mock treatment 168080.0 -16100.0 -0.43 173840.0 -9130.0 -0.25 -0.479 -0.9654 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N10 mock treatment 193400.0 9240.0 0.25 179680.0 -3290.0 -0.09 0.1117 0.4251 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N11 compound treatment 180480.0 -3680.0 -0.1 200840.0 17900.0 0.48 0.2724 0.5518 3615116 ACon1_001545 COC(/C=C/CC\C=C\C(=O)O)C(O)C(C)C(O)/C(=C/C(C)C(=O)CCCC1CC(=O)NC(=O)C1)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N12 compound treatment 202640.0 18500.0 0.49 200080.0 17100.0 0.46 0.6769 0.9995 3615120 ACon1_001546 CCCC[C@H](O)[C@@H]1CC(=CC(=O)O1)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N13 mock treatment 187880.0 3720.0 0.1 182160.0 -814.0 -0.02 0.0547 0.5373 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N14 mock treatment 186240.0 2080.0 0.06 200160.0 17200.0 0.47 0.3683 0.786 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N15 compound treatment 207280.0 23100.0 0.62 179080.0 -3890.0 -0.11 0.3627 0.5782 3615123 ACon1_001547 COC(=O)c1cccc(O)c1C(=O)c2c(O)cc(C)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N16 compound treatment 200600.0 16400.0 0.44 192000.0 9030.0 0.24 0.4837 0.9616 3615126 ACon1_001548 COc1ccc(cc1Cl)C(=O)NCCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N17 compound treatment 118960.0 -65200.0 -1.74 88400.0 -94600.0 -2.56 -3.0437 -0.9825 3615128 ACon1_001549 COc1cc(OC)c(cc1OC)c2coc3c4C=CC(C)(C)Oc4c(OC)cc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N18 compound treatment 195400.0 11200.0 0.3 175200.0 -7770.0 -0.21 0.0637 0.1737 2259 ACon1_001550 CN1CCc2cc3OCOc3cc2C(=O)Cc4ccc5OCOc5c4C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N19 compound treatment 67440.0 -117000.0 -3.12 48280.0 -135000.0 -3.65 -4.7862 -0.997 3615132 ACon1_001551 COc1ccc2C[C@@H]3[C@H](COC3=O)[C@H](OC(=O)/C(=C\C)/C)c4cc(OC)c(OC)cc4-c2c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N20 compound treatment 183760.0 -403.0 -0.01 166200.0 -16800.0 -0.45 -0.3287 -0.7237 3615136 ACon1_001552 CC(O)c1cncc2c(=O)n3CCc4c([nH]c5ccccc45)-c3cc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N21 compound treatment 148800.0 -35400.0 -0.95 72000.0 -111000.0 -3.0 -2.7933 -0.8868 3615138 ACon1_001553 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@](C)(CO)C7[C@H](O)C[C@@]6(C)[C@]5(C)CC3)[C@H](O)[C@H](O)[C@H]1O[C@@H]9OC[C@@H](O)[C@H](O[C@@H]%10OC[C@](O)(CO)[C@H]%10O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N22 compound treatment 180480.0 -3680.0 -0.1 183080.0 106.0 0.0 -0.0676 -0.6863 3615141 ACon1_001554 C/C=C(/C)\C(=O)OC1CCN2CC=C(COC(=O)C(O)(C(C)O)C(C)(C)O)C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N23 compound treatment 12120.0 -172000.0 -4.6 11720.0 -171000.0 -4.64 -6.5324 -1.0 3614951 ACon1_001555 Cc1cc(O)c2C(=O)C3=C(C(O)C(O)C(O)C3O)C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 N24 compound treatment 175160.0 -9000.0 -0.24 199200.0 16200.0 0.44 0.1403 0.2801 3615144 ACon1_001556 CO/C=C(/C1CC2N(CCC23C(=O)Nc4ccccc43)CC1C=C)\C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O01 compound treatment 210560.0 26400.0 0.71 177240.0 -5730.0 -0.16 0.3895 0.5388 3559328 ACon1_001557 CC1OC1(C)C(=O)O[C@@H]2CC[C@]3(C)CC(=O)C(=C(C)C)C[C@H]3[C@]2(C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O02 compound treatment 183360.0 -803.0 -0.02 199160.0 16200.0 0.44 0.2947 0.6717 3559070 ACon1_001558 C[C@@H]1C[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2O)[C@]5(C)[C@H](CCC=C5C)[C@@]1(C)CC[C@](C)(O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O03 compound treatment 172360.0 -11800.0 -0.32 164120.0 -18900.0 -0.51 -0.5842 -0.9733 1093459 ACon1_001559 COc1cc(CC2COC(=O)C2(O)Cc3ccc(O)c(OC)c3)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O04 compound treatment 63600.0 -121000.0 -3.22 68160.0 -115000.0 -3.11 -4.4783 -0.9998 3559095 ACon1_001560 C/C=C(/C)\C(=O)O[C@H]1C[C@]2(C)O[C@@H]2[C@H]3O[C@H]3C(=C)[C@@H](O)[C@H]4OC(=O)C(=C)[C@@H]41 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O05 compound treatment 211920.0 27800.0 0.74 167640.0 -15300.0 -0.42 0.2315 0.2721 3558913 ACon1_001561 OC(=O)C[C@](O)(Cc1ccc(O)cc1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O06 compound treatment 223640.0 39500.0 1.06 215280.0 32300.0 0.87 1.3651 0.9956 3559222 ACon1_001562 COc1c(O)cc(cc1O)c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]4O[C@@H](C)[C@H](OC(=O)C)[C@@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O07 compound treatment 192160.0 8000.0 0.21 163520.0 -19500.0 -0.53 -0.2211 -0.389 3557351 ACon1_001563 C[C@@H](OC(=O)C)[C@@H]1[C@]23O[C@@]3([C@H](O)c4c(O)c(ccc4C2=O)c5ccc6C(=O)[C@@]78O[C@@]8([C@H](O)c6c5O)C(=O)C[C@](C)(O)[C@@H]7[C@@H](C)OC(=O)C)C(=O)C[C@]1(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O08 compound treatment 223200.0 39000.0 1.04 164320.0 -18700.0 -0.51 0.3813 0.3287 3559212 ACon1_001564 CC(C)C(C)(O)C(=O)OCC1=CCN2CCC(O)C21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O09 compound treatment 122640.0 -61500.0 -1.65 53760.0 -129000.0 -3.5 -3.6372 -0.9408 3615151 ACon1_001565 C[C@@H]1C2[C@H](CC3[C@@H]4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)O[C@@]91CC[C@@](C)(CO[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)O9 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O10 compound treatment 174200.0 -9960.0 -0.27 154280.0 -28700.0 -0.78 -0.7377 -0.8983 3557334 ACon1_001566 CC(C)(C=C)[C@]12C[C@@H]3N([C@@H]2Nc4ccccc41)C(=O)/C(=C/c5cnc[nH]5)/NC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O11 mock treatment 177720.0 -6440.0 -0.17 162560.0 -20400.0 -0.55 -0.5126 -0.8855 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O12 mock treatment 208480.0 24300.0 0.65 176440.0 -6530.0 -0.18 0.3349 0.4968 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O13 compound treatment 14960.0 -169000.0 -4.53 14920.0 -168000.0 -4.55 -6.4174 -1.0 3554512 ACon1_001567 CO[C@H]1/C=C/C=C(\C)/C[C@H](C)[C@H](O)[C@H](C)/C=C(\C)/C=C(\OC)/C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)C(=O)\C=C\[C@H](C)[C@H](O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O14 compound treatment 205480.0 21300.0 0.57 175400.0 -7570.0 -0.21 0.2582 0.4261 3180421 ACon1_001568 COc1ccc2[C@@H]3COc4cc(O)ccc4[C@@H]3Oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O15 compound treatment 206240.0 22100.0 0.59 181880.0 -1090.0 -0.03 0.3966 0.6708 3557322 ACon1_001569 CC/C=C/C=C/1\CO[C@@]2(CC[C@@H](CO)O2)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O16 compound treatment 213120.0 29000.0 0.77 206720.0 23700.0 0.64 1.0023 0.9957 3557362 ACon1_001570 CC(=O)c1nc2ccccc2c(=O)[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O17 compound treatment 14240.0 -170000.0 -4.55 11440.0 -172000.0 -4.64 -6.4977 -0.9999 3553815 ACon1_001571 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)C(O)[C@@H](C)C(=O)[C@@](C)(O)C(O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O18 compound treatment 134000.0 -50200.0 -1.34 127120.0 -55900.0 -1.51 -2.018 -0.9982 3558879 ACon1_001572 CC(CO)C(=O)O[C@H]1C/C(=C/CC/C(=C/[C@H]2OC(=O)C(=C)[C@@H]21)/CO)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O19 compound treatment 12720.0 -171000.0 -4.59 10160.0 -173000.0 -4.68 -6.5509 -1.0 3554106 ACon1_001573 CCC(C)(O)C(=O)O[C@@H]1[C@H]2[C@@H](C)[C@@H](O)[C@]3(O)OC[C@]42[C@H]3[C@@]5(C)[C@H](O)C(=O)C=C(C)[C@@H]5C[C@H]4OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O20 compound treatment 145160.0 -39000.0 -1.04 103600.0 -79400.0 -2.15 -2.2572 -0.9449 3559210 ACon1_001574 C[C@@]1(CO)CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3(CC4=C)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O21 compound treatment 205680.0 21500.0 0.58 219160.0 36200.0 0.98 1.0997 0.9679 3558433 ACon1_001575 CC1OC(OC2C(OC3OCC(O)C(O)C3O)C(OCCc4ccc(O)c(O)c4)OC(CO)C2OC(=O)/C=C/c5ccc(O)c(O)c5)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O22 compound treatment 99080.0 -85100.0 -2.28 45960.0 -137000.0 -3.71 -4.2322 -0.9725 3557365 ACon1_001576 CC(=O)O[C@@H]1C[C@@]2(C)[C@]3(CO3)[C@@H]1O[C@@H]4C=C(C)C(O)[C@H](O)[C@@]42C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O23 compound treatment 182560.0 -1600.0 -0.04 180920.0 -2050.0 -0.06 -0.0696 -0.9917 3558906 ACon1_001577 CCC(C)C(=O)OC/C=C(\C)/CC[C@H]1C(=C)C(O)CC2[C@@](C)(COC(=O)C)CC(O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 O24 compound treatment 199600.0 15400.0 0.41 202840.0 19900.0 0.54 0.6723 0.9915 3557395 ACon1_001578 CC1(CO)CC(O)CC2(C)C1CCC3=C2COC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P01 compound treatment 163000.0 -21200.0 -0.57 162960.0 -20000.0 -0.54 -0.7834 -0.9998 1000475 ACon1_001579 O=c1ccc2cc3ccoc3cc2o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P02 compound treatment 134000.0 -50200.0 -1.34 130160.0 -52800.0 -1.43 -1.9598 -0.9995 3615161 ACon1_001580 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)[C@](C)(C5CC[C@]43C)C(=O)O)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P03 compound treatment 217800.0 33600.0 0.9 203120.0 20100.0 0.55 1.0219 0.9712 3553075 ACon1_001581 C[C@H]1[C@H](O)CCC2=CC(=O)C(=C[C@]12C)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P04 compound treatment 108240.0 -75900.0 -2.03 88360.0 -94600.0 -2.56 -3.2472 -0.9934 3615165 ACon1_001582 Cc1cc(O)c(C)c2Oc3c(C)c(O)c(O)c(C)c3OC(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P05 compound treatment 204800.0 20600.0 0.55 192360.0 9390.0 0.25 0.57 0.938 3615168 ACon1_001583 Oc1cccc2C(=O)Nc3ccccc3-c4nc5ccccc5c(=O)n4-c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P06 compound treatment 199760.0 15600.0 0.42 194960.0 12000.0 0.32 0.5245 0.9923 3615170 ACon1_001584 CC1CC(OC=O)C2C(C)C(CCC2(C)C31CCC4(COC(=O)C4)O3)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P07 compound treatment 12600.0 -172000.0 -4.59 10160.0 -173000.0 -4.68 -6.5532 -1.0 3615172 ACon1_001585 COC1CC(OC2C(C)OC(CC2OC)OC3C(C)OC(CC3OC)OC4C(C)OC(CC4OC)O[C@H]5CC[C@]6(C)C7CC(OC(=O)c8ccccc8)[C@]9(C)[C@@](O)(CC[C@]9(O)[C@]7(O)CC=C6C5)C(=O)C)OC(C)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P08 compound treatment 200760.0 16600.0 0.44 184120.0 1150.0 0.03 0.3359 0.7547 3615176 ACon1_001586 O[C@@H]1[C@@H](O)[C@H](Oc2c(O)c(c(O)cc2c3ccccc3)c4ccccc4)O[C@@H]([C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P09 compound treatment 214840.0 30700.0 0.82 190000.0 7030.0 0.19 0.7147 0.8485 3615180 ACon1_001587 Cc1cc2C(=O)c3ccccc3C(=O)c2cc1O[C@@H]4O[C@H](CO[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P10 compound treatment 187760.0 3600.0 0.1 172520.0 -10500.0 -0.28 -0.1321 -0.4418 3615183 ACon1_001588 CC(=O)[C@@]12C[C@@H](CC[C@@]2(C)CC[C@@H]1O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P11 mock treatment 208040.0 23900.0 0.64 175800.0 -7170.0 -0.19 0.3143 0.4708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P12 mock treatment 201840.0 17700.0 0.47 179520.0 -3450.0 -0.09 0.2682 0.5565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P13 compound treatment 204560.0 20400.0 0.55 176120.0 -6850.0 -0.19 0.2546 0.4418 3615185 ACon1_001589 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)CO[C@@H](O[C@H]3[C@H](C)O[C@@H](O[C@@H]4[C@@H](O)[C@@H](O)CO[C@H]4OC(=O)[C@@]56CCC(C)(C)C[C@H]6C7=CCC8[C@@]9(C)C[C@H](O)[C@H](O[C@@H]%10O[C@@H]([C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@@](C)(CO)C9[C@H](O)C[C@@]8(C)[C@]7(C)C[C@H]5O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P14 compound treatment 13880.0 -170000.0 -4.55 12280.0 -171000.0 -4.62 -6.4884 -1.0 3615189 ACon1_001590 COc1cc(nc(/C=N/O)c1S(=O)C)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P15 compound treatment 234720.0 50600.0 1.35 187720.0 4750.0 0.13 1.0471 0.7708 3557312 ACon1_001591 CC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC3CCC(O3)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P16 compound treatment 207320.0 23200.0 0.62 167720.0 -15300.0 -0.41 0.146 0.1961 3615194 ACon1_001592 CC(C)(C=C)C12CC3N(C2Nc4ccccc41)C(=O)C(Cc5c[nH]cn5)NC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P17 compound treatment 205160.0 21000.0 0.56 169520.0 -13500.0 -0.36 0.1396 0.2085 3558732 ACon1_001593 O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P18 compound treatment 197600.0 13400.0 0.36 183960.0 986.0 0.03 0.273 0.7575 3615196 ACon1_001594 COC(=O)C1(CO)C/2CCN(C\C2=C/C)Cc3c1[nH]c4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P19 compound treatment 189360.0 5200.0 0.14 190720.0 7750.0 0.21 0.2466 0.9801 3615200 ACon1_001595 C/C(=C\CCC(C)(O)C=C)/C(=O)OC1C2OC2(C)C3C(OC4OC(COC5OC(CO)C(O)C(O)C5O)C(O)C(O)C4O)OC=CC13O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P20 compound treatment 209320.0 25200.0 0.67 188480.0 5510.0 0.15 0.5812 0.8433 2096349 ACon1_001596 COc1cc2CCN(C)C3(Cc4ccc5OCOc5c4C3=O)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P21 compound treatment 178000.0 -6160.0 -0.16 168200.0 -14800.0 -0.4 -0.3994 -0.9232 1054272 ACon1_001597 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P22 compound treatment 191040.0 6880.0 0.18 182040.0 -934.0 -0.03 0.1122 0.6042 1874510 ACon1_001598 CC1C2C(CC3C4CC=C5CC(O)CCC5(C)C4CCC23C)OC61CCC(C)CN6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P23 compound treatment 179480.0 -4680.0 -0.13 207880.0 24900.0 0.67 0.3882 0.5661 3615206 ACon1_001599 CC1OC(O[C@H]2[C@@H](O)C[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)OC7OC(C)C(OC8OCC(OC9OCC(O)C(OC%10OCC(O)C(O)C%10O)C9O)C(O)C8O)C(O)C7O)[C@]2(C)CO)C(O)C(OC%11OC(CO)C(O)C(O)C%11O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2294 P24 compound treatment 169040.0 -15100.0 -0.4 182040.0 -934.0 -0.03 -0.3039 -0.7499 1707947 ACon1_001600 CN1CCc2cc3OCOc3cc2C1C4OC(=O)c5c6OCOc6ccc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A01 compound treatment 248920.0 79300.0 2.12 255880.0 85100.0 2.3 3.1292 0.9991 3615211 ACon1_001601 COc1cc2CCN(C)C3Cc4ccc(O)c(O)c4-c(c1OC)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A02 compound treatment 250600.0 81000.0 2.17 257040.0 86300.0 2.34 3.1832 0.9993 3615213 ACon1_001602 CC1OC(Oc2cc(O)c(C3OC(C)C(O)C(O)C3O)c4oc(cc(=O)c24)c5ccc(O)cc5)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A03 compound treatment 174480.0 4860.0 0.13 210400.0 39600.0 1.07 0.8506 0.787 3484788 ACon1_001603 CCC(C)C1NC(=O)C2CCCN2C(=O)C(CC=C)OC(=O)CCNC(=O)C(C)N(C)C(=O)C(C(C)C)N(C)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A04 compound treatment 256600.0 87000.0 2.33 279880.0 109000.0 2.95 3.7339 0.993 3615215 ACon1_001604 COc1cc(cc(OC)c1O)C(=O)OC[C@@]2(O)CO[C@H](OC3C(O)C(O)C(Oc4cc(OC)c(OC)c(OC)c4)OC3CO)[C@@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A05 compound treatment 202480.0 32900.0 0.88 213520.0 42800.0 1.16 1.4399 0.9908 3557487 ACon1_001605 CC1(O)CC2(CC1CCC23)CC(=O)C4C(CO)(CCCC34C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A06 compound treatment 206760.0 37100.0 0.99 208440.0 37700.0 1.02 1.4236 0.9999 3615219 ACon1_001606 CCCCCC(=O)CC(O)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A07 compound treatment 187400.0 17800.0 0.48 210120.0 39400.0 1.07 1.0896 0.9339 3553900 ACon1_001607 CC1[C@H]2[C@@H](CC1=O)C(=C)C[C@@H](O)[C@@H]3[C@@H]2OC(=O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A08 compound treatment 85960.0 -83700.0 -2.24 166440.0 -4330.0 -0.12 -1.6652 -0.7431 3615221 ACon1_001608 CC1(CCCC2(C)C1C(O)CC3(CC4(O)CC=C32)C(=O)C4=C)C(=O)OC5OC(CO)C(O)C(O)C5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A09 compound treatment 196840.0 27200.0 0.73 213920.0 43200.0 1.17 1.3409 0.9741 3615223 ACon1_001609 C[C@@]1(O)C[C@@H](O)C[C@]2(C)CC[C@H](CC12)C(=C)C(=O)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A10 compound treatment 198440.0 28800.0 0.77 215480.0 44700.0 1.21 1.401 0.9763 3615227 ACon1_001610 C[C@@]12CCC[C@@]3(C)C2[C@@H](C[C@@]4(CO4)[C@]3(O)CCc5ccoc5)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A11 compound treatment 198920.0 29300.0 0.78 230560.0 59800.0 1.62 1.6988 0.9446 1088391 ACon1_001611 CC1=CC(=O)c2c(O)cccc2C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A12 compound treatment 205640.0 36000.0 0.96 218440.0 47700.0 1.29 1.5939 0.9896 3615231 ACon1_001612 COC(/C=C/C(OC(=O)C)C(C)OC(=O)C)C(O)C1CC=CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A13 mock treatment 203880.0 34300.0 0.92 236960.0 66200.0 1.79 1.9151 0.9515 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A14 mock treatment 189600.0 20000.0 0.53 197200.0 26400.0 0.72 0.8839 0.9897 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A15 compound treatment 191880.0 22300.0 0.6 205600.0 34800.0 0.94 1.0878 0.9754 3615235 ACon1_001613 OC1Cc2c(O)c3C(C(O)C(Oc3cc2OC1c4ccc(O)c(O)c4)c5ccc(O)c(O)c5)c6ccc(O)cc6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A16 compound treatment 58480.0 -111000.0 -2.97 96760.0 -74000.0 -2.0 -3.5189 -0.9816 3615238 ACon1_001614 CC(C)/C=C/C=C(\C)/CC/C=C(\C)/CCOc1c(O)cc2C(=O)NCc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A17 compound treatment 9960.0 -160000.0 -4.27 11920.0 -159000.0 -4.3 -6.0607 -1.0 3615241 ACon1_001615 C[C@@H]1O[C@@H](OC(=O)c2c(C)coc2C)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A18 compound treatment 190720.0 21100.0 0.56 209520.0 38800.0 1.05 1.1409 0.9577 3615246 ACon1_001616 C[C@@H]1O[C@@H](OC2C(O)C(O)C(OC3C(O)COC(O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7C8CC(C)(C)CC[C@@]8(CC[C@]76C)C(=O)OC9OC(CO)C(O)C(O)C9O)C4(C)C)C3O)OC2C(=O)O)[C@H](O)[C@H](OC%10OC(CO)C(O)C(O)C%10O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A19 compound treatment 183640.0 14000.0 0.37 211000.0 40200.0 1.09 1.0354 0.8988 3615250 ACon1_001617 OC1CCC(=O)c2c(O)cccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A20 compound treatment 18280.0 -151000.0 -4.05 22960.0 -148000.0 -4.0 -5.692 -1.0 3559151 ACon1_001618 CC(CCC1(O)OC2CC3C4CCC5CC(CCC5(C)C4CCC3(C)C2C1C)OC6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)COC8OC(CO)C(O)C(O)C8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A21 compound treatment 204520.0 34900.0 0.93 230600.0 59800.0 1.62 1.8055 0.9657 3615252 ACon1_001619 OC(=O)CCCCCCC/C=C\CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A22 compound treatment 227880.0 58300.0 1.56 217200.0 46400.0 1.26 1.9908 0.9943 1018507 ACon1_001620 Oc1ccc(C=O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A23 compound treatment 61600.0 -108000.0 -2.89 95000.0 -75800.0 -2.05 -3.4936 -0.9859 3615257 ACon1_001621 CC(=O)OC(CCCCc1ccc(O)c(O)c1)CCc2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 A24 compound treatment 239920.0 70300.0 1.88 234840.0 64100.0 1.73 2.5562 0.9992 3559182 ACon1_001622 COc1cc(cc(OC)c1O)C2OC[C@@H]3[C@H](OC[C@H]23)c4cc(OC)c(O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B01 compound treatment 251400.0 81800.0 2.19 243880.0 73100.0 1.98 2.9464 0.9988 3615259 ACon1_001623 COc1cc(/C=C/C(=O)O[C@@H]2[C@H](O)[C@@H](OC3OC(CO)C(O)C(O)C3O)[C@H](C)O[C@H]2OCC4OC(Oc5c(oc6cc(O)cc(O)c6c5=O)c7ccc(O)cc7)C(O)C(O)C4O)cc(OC)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B02 compound treatment 201840.0 32200.0 0.86 213800.0 43000.0 1.17 1.4332 0.989 3615262 ACon1_001624 OCCCCCCCC=C(C(=O)O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B03 compound treatment 243880.0 74300.0 1.99 232160.0 61400.0 1.66 2.5798 0.9961 3615264 ACon1_001625 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B04 compound treatment 134680.0 -34900.0 -0.93 193800.0 23000.0 0.62 -0.22 -0.1958 3615266 ACon1_001626 CN1C(=O)c2ccccc2-n3c(nc4ccccc4c3=O)[C@]51O[C@H]5c6ccccc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B05 compound treatment 11360.0 -158000.0 -4.23 12880.0 -158000.0 -4.27 -6.0158 -1.0 3615270 ACon1_001627 COc1c(Cc2ccccc2O)c(O)c(Cc3ccccc3O)c(O)c1C(=O)CCc4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B06 compound treatment 12240.0 -157000.0 -4.21 13240.0 -158000.0 -4.26 -5.9923 -1.0 3615272 ACon1_001628 CCC(C)CC(C)/C=C\C1OC2=C(C(O)C1O)C(=O)OC2(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B07 compound treatment 197880.0 28300.0 0.76 225160.0 54400.0 1.47 1.5758 0.952 3615275 ACon1_001629 CC(=CCCC(C)(O)C(O)Cc1cc(cc(CC=C(C)C)c1O)C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B08 compound treatment 176040.0 6420.0 0.17 185960.0 15200.0 0.41 0.4123 0.9249 3054974 ACon1_001630 COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]21 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B09 compound treatment 179360.0 9740.0 0.26 197560.0 26800.0 0.73 0.6971 0.9045 3615278 ACon1_001631 CC(=O)c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(/C=C/C(C)(C)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B10 compound treatment 159880.0 -9740.0 -0.26 186840.0 16100.0 0.44 0.1234 0.2434 3559815 ACon1_001632 COc1cc(ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c3oc4cc(O)cc(O)c4c(=O)c3O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B11 compound treatment 99000.0 -70600.0 -1.89 104520.0 -66200.0 -1.79 -2.6039 -0.9997 3559060 ACon1_001633 COc1cc2OC[C@@H]3Oc4c5C[C@H](Oc5ccc4C(=O)[C@]3(O)c2cc1OC)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B12 compound treatment 20640.0 -149000.0 -3.99 18560.0 -152000.0 -4.12 -5.7316 -0.9999 3076873 ACon1_001634 COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)/C=C/c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B13 mock treatment 163640.0 -5980.0 -0.16 188400.0 17600.0 0.48 0.2244 0.4457 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B14 mock treatment 174240.0 4620.0 0.12 181880.0 11100.0 0.3 0.3001 0.9227 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B15 compound treatment 162480.0 -7140.0 -0.19 192840.0 22100.0 0.6 0.2875 0.4582 3615283 ACon1_001635 COc1cc(oc(=O)c1C)C(C)C=C(C)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B16 compound treatment 123840.0 -45800.0 -1.22 135760.0 -35000.0 -0.95 -1.5361 -0.992 3615285 ACon1_001636 OC(=O)c1cc(O)c(O)c(O)c1c2c(O)c(O)c3oc(=O)c4cc(O)c(O)c5oc(=O)c2c3c45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B17 compound treatment 173720.0 4100.0 0.11 197920.0 27200.0 0.74 0.5973 0.8037 3615286 ACon1_001637 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(O)C6O)C(=O)O)C(CO)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)OC7OC(CO)C(OC8OC(CO)C(O)C(O)C8O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B18 compound treatment 179120.0 9500.0 0.25 185720.0 15000.0 0.4 0.4659 0.9748 3615290 ACon1_001638 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@H]4O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c(oc3c2)c7ccc(O)c(O)c7)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B19 compound treatment 164680.0 -4940.0 -0.13 189400.0 18600.0 0.5 0.2632 0.5048 3615295 ACon1_001639 COc1cc2c(cc1O)C(=O)CC3C(C)(C)C(=O)CCC32C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B20 compound treatment 189600.0 20000.0 0.53 198560.0 27800.0 0.75 0.9099 0.9859 3615297 ACon1_001640 CC1(CCO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC3C(=CCC4[C@@](C)(CCC[C@]34C)C(=O)O)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B21 compound treatment 127080.0 -42500.0 -1.14 139080.0 -31700.0 -0.86 -1.4112 -0.9903 3615299 ACon1_001641 COC1(C)C(O)C(=O)C(=C(Oc2cc(C)cc(O)c2C)C1=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B22 compound treatment 178960.0 9340.0 0.25 207520.0 36800.0 1.0 0.8802 0.858 3615301 ACon1_001642 COc1cc(/C=C/COC2OC(CO)C(O)C(O)C2O)cc3C(CO)C(Oc31)c4ccc(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B23 compound treatment 211760.0 42100.0 1.13 202520.0 31800.0 0.86 1.4049 0.9911 3615306 ACon1_001643 COc1cc2oc(cc(=O)c2c(OC)c1OC)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 B24 compound treatment 241080.0 71500.0 1.91 227000.0 56200.0 1.52 2.4281 0.9936 3558267 ACon1_001644 C[C@@]12CC[C@@H](O)C(=C)C2C[C@@H](CC1)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C01 compound treatment 203040.0 33400.0 0.89 205000.0 34200.0 0.93 1.2874 0.9998 3615308 ACon1_001645 COC(=O)[C@@H]1C[C@@]2(C=CC[N+]3([O-])CC[C@]45[C@H]23)C(C)[C@]51Nc6ccccc64 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C02 compound treatment 207880.0 38300.0 1.02 204560.0 33800.0 0.91 1.3705 0.9984 3615312 ACon1_001646 OCC1OC(OCC2OC(OC(CCc3ccccc3)CC(=O)CCc4ccccc4)C(O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C03 compound treatment 193480.0 23900.0 0.64 205040.0 34300.0 0.93 1.1074 0.9833 3554647 ACon1_001647 COC(=O)C(=C)[C@]1(O[C@@]/23CC[C@@](C)(O)CC1=O)[C@H](C[C@@]3(C)OC(=O)\C2=C\C)OC(=O)C(=C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C04 compound treatment 179880.0 10300.0 0.27 176800.0 6030.0 0.16 0.3095 0.9693 3615314 ACon1_001648 COc1cc(cc(OC)c1O)C(=O)OC[C@@]2(O)CO[C@H](OC3C(O)C(O)C(OC(C)/C=C/C4(O)C(C)CC(O)CC4(C)C)OC3CO)[C@@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C05 compound treatment 174320.0 4700.0 0.13 179600.0 8830.0 0.24 0.258 0.9549 3553387 ACon1_001649 CC(=O)OC1CC2C(C=C1C)C(C(CC2(C)O)OC(=O)/C(=C/CO)/CO)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C06 compound treatment 257520.0 87900.0 2.35 197960.0 27200.0 0.74 2.1831 0.8861 3615318 ACon1_001650 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@H]1C)C(=O)OC6OC(COC7OC(CO)C(O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)C(O)C7O)C(O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C07 compound treatment 12280.0 -157000.0 -4.21 25320.0 -145000.0 -3.94 -5.7603 -0.9994 3558295 ACon1_001651 CC(C)c1cc2CCC3C(C)(C)C[C@H](O)C[C@]3(C)c2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C08 compound treatment 179800.0 10200.0 0.27 184200.0 13400.0 0.36 0.4497 0.9898 3615325 ACon1_001652 CC1OC(OC2C(O)C(O)C(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)OC8OC(CO)C(O)C(O)C8O)C3(C)C)OC2C(=O)O)C(OC9OCC(O)C(O)C9O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C09 compound treatment 193080.0 23500.0 0.63 174520.0 3750.0 0.1 0.5156 0.8111 3558212 ACon1_001653 C[C@@]1(O)CCC2[C@H](OC(=O)C2=C)[C@@H]3[C@H]1C[C@H](O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C10 compound treatment 222920.0 53300.0 1.43 192680.0 21900.0 0.59 1.4276 0.9245 3615328 ACon1_001654 CC1OC(OCC2OC(OCC3(C)C(O)CCC4(C)C3CCC5(C)C4CCC6C7=CC(C)(C)CCC7(CCC65C)C(=O)O)C(O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C11 mock treatment 180560.0 10900.0 0.29 180320.0 9550.0 0.26 0.3898 0.9981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C12 mock treatment 172280.0 2660.0 0.07 172040.0 1270.0 0.03 0.0747 0.9448 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C13 compound treatment 193440.0 23800.0 0.64 182840.0 12100.0 0.33 0.6816 0.9519 3553489 ACon1_001655 CC(C)[C@@H](NC(=O)C)C(=O)O[C@H]1CCC(C)(C)[C@@H]2CCC3=C(COC3=O)[C@@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C14 compound treatment 35440.0 -134000.0 -3.59 49440.0 -121000.0 -3.28 -4.8605 -0.999 3615331 ACon1_001656 CCCCCCCCC/C=C/CCCCC(=O)C1C(=O)CCC(O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C15 mock treatment 155080.0 -14500.0 -0.39 180360.0 9590.0 0.26 -0.0914 -0.1954 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C16 mock treatment 171600.0 1980.0 0.05 180440.0 9670.0 0.26 0.2226 0.8331 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C17 compound treatment 184600.0 15000.0 0.4 196920.0 26200.0 0.71 0.784 0.9636 3615336 ACon1_001657 OC(=O)C(OC(=O)/C=C/c1ccc(O)c(O)c1)C(OC(=O)/C=C/c2ccc(O)c(O)c2)C(OC(=O)/C=C/c3ccc(O)c(O)c3)C(OC(=O)/C=C/c4ccc(O)c(O)c4)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C18 compound treatment 13080.0 -157000.0 -4.19 49080.0 -122000.0 -3.29 -5.2903 -0.993 3615339 ACon1_001658 CC(C)/C=C/C=C(\C)/CCC\C(=C\COc1c(O)cc2C(=O)NCc2c1O)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C19 compound treatment 9720.0 -160000.0 -4.28 12360.0 -158000.0 -4.29 -6.0568 -1.0 3554116 ACon1_001659 CCC(C)[C@@H]1N(C)C(=O)[C@@H](CC(C)C)OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C20 compound treatment 166400.0 -3220.0 -0.09 164880.0 -5890.0 -0.16 -0.1736 -0.9584 3615343 ACon1_001660 C[C@H]1O[C@@H](O[C@H]2C[C@@H]3[C@@H](CC2(C)C)C4=CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(C=O)C6CC[C@@]5(C)[C@]4(C)CC3=O)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C21 compound treatment 202120.0 32500.0 0.87 203560.0 32800.0 0.89 1.2425 0.9999 3558893 ACon1_001661 Oc1ccc(CCNC(=O)/C=C/c2ccc(O)c(O)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C22 compound treatment 11920.0 -158000.0 -4.22 48960.0 -122000.0 -3.3 -5.3146 -0.9926 3559174 ACon1_001662 OC[C@H]1O[C@@H](Oc2cc(O)cc3OC(CC(=O)c23)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C23 compound treatment 85160.0 -84500.0 -2.26 94160.0 -76600.0 -2.07 -3.064 -0.9991 3615348 ACon1_001663 OCC(=C)C(=O)O[C@H]1CC(=C)[C@@H]2C[C@H](O)C(=C)[C@@H]2[C@H]3OC(=O)C(CN4CCCC4C(=O)O)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 C24 compound treatment 22800.0 -147000.0 -3.93 19640.0 -151000.0 -4.09 -5.6701 -0.9998 3559220 ACon1_001664 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H]1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D01 compound treatment 217840.0 48200.0 1.29 204320.0 33600.0 0.91 1.5543 0.9853 3615352 ACon1_001665 C/C(=C\Cc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc3ccc(=O)oc13)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D02 compound treatment 230720.0 61100.0 1.63 241360.0 70600.0 1.91 2.507 0.997 3615355 ACon1_001666 O[C@@H]1CC(=O)c2cccc(O)c2[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D03 compound treatment 15000.0 -155000.0 -4.14 18240.0 -153000.0 -4.13 -5.8444 -1.0 3615359 ACon1_001667 OCCCCC/C=C\C/C=C\C(O)CC1CCC(CC(=O)O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D04 compound treatment 45240.0 -124000.0 -3.33 71640.0 -99100.0 -2.68 -4.2502 -0.9943 3615363 ACon1_001668 COCC1OC(OC(C)(C)C2CCC3(C)C=C(CCC3O2)C4CCC5C4(C)CC(O)C6OC(CCC56C)C(C)(C)OC7OC(CO)C(O)C(O)C7NC(=O)C)C(NC(=O)C)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D05 compound treatment 212560.0 42900.0 1.15 277800.0 107000.0 2.9 2.8611 0.9179 3615365 ACon1_001669 Cc1cc(O)c2c(=O)c3c(cc(O)cc3oc2c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D06 compound treatment 12880.0 -157000.0 -4.19 14720.0 -156000.0 -4.22 -5.9519 -1.0 3615368 ACon1_001670 CCC(C)C1NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)CC(CCCCCCCCCC(C)C)OC1=O)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D07 compound treatment 186080.0 16500.0 0.44 212880.0 42100.0 1.14 1.1175 0.9143 3615370 ACon1_001671 CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H](O)COc2c3ccoc3cc4oc(=O)ccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D08 compound treatment 179000.0 9380.0 0.25 176320.0 5550.0 0.15 0.2837 0.97 3554551 ACon1_001672 COC(=O)[C@]1(C)CC[C@@H](OC(=O)C)[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3([C@H](OC(=O)C)C4=C)[C@H](CC12)OC(=O)[C@]5(C)O[C@@H]5C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D09 compound treatment 135360.0 -34300.0 -0.92 117400.0 -53400.0 -1.44 -1.6696 -0.9759 3615375 ACon1_001673 ON1CCCCCNC(=O)CCC(=O)N(O)CCCCNC(=O)CCC(=O)N(O)CCCCNC(=O)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D10 compound treatment 18280.0 -151000.0 -4.05 15760.0 -155000.0 -4.2 -5.8298 -0.9998 3559785 ACon1_001674 COc1ccc(cc1)C2CC(=O)c3c(O)c(CC=C(C)C)c(O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D11 mock treatment 179200.0 9580.0 0.26 201160.0 30400.0 0.82 0.763 0.8854 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D12 mock treatment 204000.0 34400.0 0.92 196800.0 26000.0 0.7 1.1486 0.9914 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D13 compound treatment 113320.0 -56300.0 -1.51 121600.0 -49200.0 -1.33 -2.0061 -0.9981 3559167 ACon1_001675 COc1cc(/C=C/CO)cc2[C@@H](CO)[C@H](Oc21)c3ccc(OC4OC(CO)C(O)C(O)C4O)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D14 compound treatment 13160.0 -156000.0 -4.19 16640.0 -154000.0 -4.17 -5.9098 -1.0 3615378 ACon1_001676 CCCCCCc1cc(O)c(C)c(OC(=O)C)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D15 mock treatment 162880.0 -6740.0 -0.18 211840.0 41100.0 1.11 0.6588 0.5848 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D16 mock treatment 172560.0 2940.0 0.08 213040.0 42300.0 1.14 0.8648 0.7539 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D17 compound treatment 183000.0 13400.0 0.36 212960.0 42200.0 1.14 1.0608 0.8862 3615380 ACon1_001677 COc1cc(oc(=O)c1C)C(C)CC(C)(O)CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D18 compound treatment 213240.0 43600.0 1.17 204400.0 33600.0 0.91 1.4689 0.9925 3615382 ACon1_001678 COC(=O)C[C@H]1C(C)(C)[C@H](OC(=O)C)[C@]2(O)CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D19 compound treatment 20880.0 -149000.0 -3.98 29400.0 -141000.0 -3.83 -5.5195 -0.9998 3559250 ACon1_001679 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](OC6OC(C(O)C(O)C6O)C(=O)O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D20 compound treatment 9480.0 -160000.0 -4.28 11640.0 -159000.0 -4.31 -6.0751 -1.0 3615386 ACon1_001680 COc1ccc(/C=C/c2cc(OC)cc(O)c2CC=C(C)C)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D21 compound treatment 161520.0 -8100.0 -0.22 174840.0 4070.0 0.11 -0.0752 -0.3095 3615390 ACon1_001681 CC/C=C\CC/1C(=O)C=C\C1=C\CCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D22 compound treatment 219200.0 49600.0 1.33 228320.0 57600.0 1.56 2.0395 0.9968 3615393 ACon1_001682 CC1C2C(O)C(=O)C3(C)C(CCC4/C(=C(\CCC=C(C)C)/C(=O)O)/C(CC43C)OC(=O)C)C2(C)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D23 compound treatment 40160.0 -129000.0 -3.46 33240.0 -138000.0 -3.72 -5.0814 -0.9993 3559227 ACon1_001683 COc1cc(O[C@@H]2O[C@H](CO[C@H]3OC[C@](O)(COC(=O)c4ccc(O)c(OC)c4)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 D24 compound treatment 185720.0 16100.0 0.43 199400.0 28600.0 0.78 0.8526 0.9615 3615396 ACon1_001684 CCN1C[C@]2(C)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@](O)(C[C@@H]5OC)C6[C@@H](OC)C32)[C@@H]61 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E01 mock treatment 186560.0 16900.0 0.45 172120.0 1350.0 0.04 0.3463 0.7618 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E02 mock treatment 195760.0 26100.0 0.7 201960.0 31200.0 0.84 1.0915 0.9956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E03 compound treatment 12840.0 -157000.0 -4.19 12920.0 -158000.0 -4.27 -5.9871 -1.0 3557617 ACon1_001685 CC1CC[C@H](OC(=O)c2ccoc2)[C@@]3(C)[C@H](C[C@@H]4C[C@]13OC4(C)C)OC(=O)c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E04 compound treatment 172320.0 2700.0 0.07 172120.0 1350.0 0.04 0.077 0.9507 3615401 ACon1_001686 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@@H](OC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E05 compound treatment 113160.0 -56500.0 -1.51 153480.0 -17300.0 -0.47 -1.3988 -0.8847 3557658 ACon1_001687 COc1c(oc2cc(O)cc(O)c2c1=O)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E06 compound treatment 157480.0 -12100.0 -0.32 179960.0 9190.0 0.25 -0.0537 -0.1311 3615406 ACon1_001688 CO[C@@H]1[C@@H](C)O[C@@H](OC2CC3C(=CC2(C)C=C)CCC4C(C)(C)C(CCC34C)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E07 compound treatment 19600.0 -150000.0 -4.01 27920.0 -143000.0 -3.87 -5.5721 -0.9998 3552666 ACon1_001689 C[C@@H]1C[C@H]2OCC3=CCC[C@@H]([C@@]23CO)[C@]1(CC(O)c4ccoc4)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E08 compound treatment 156880.0 -12700.0 -0.34 169560.0 -1210.0 -0.03 -0.2641 -0.7713 3615410 ACon1_001690 COC1OC(O)C(O)C21CC[C@@]3(O2)[C@H](C)C[C@H]4OC(=O)[C@@]5(C)CCC[C@]3(C)C45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E09 mock treatment 146600.0 -23000.0 -0.62 165960.0 -4810.0 -0.13 -0.5274 -0.838 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E10 mock treatment 166760.0 -2860.0 -0.08 161840.0 -8930.0 -0.24 -0.225 -0.8876 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E11 compound treatment 163680.0 -5940.0 -0.16 174840.0 4070.0 0.11 -0.0344 -0.1778 3615414 ACon1_001691 CC(C)CCCC(C)(O)c1ccc(cc1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E12 compound treatment 165640.0 -3980.0 -0.11 156720.0 -14000.0 -0.38 -0.3442 -0.8716 3615416 ACon1_001692 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)CC[C@@]31O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E13 compound treatment 170280.0 658.0 0.02 163440.0 -7330.0 -0.2 -0.1278 -0.6418 905 ACon1_001693 CO[C@@H]1[C@@H](OC(=O)N)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E14 compound treatment 165800.0 -3820.0 -0.1 186360.0 15600.0 0.42 0.2262 0.5208 3615420 ACon1_001694 CC1CCC2(C)C(CC(O)C(O)C2(O)CO)C1(C)CCc3ccoc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E15 compound treatment 186200.0 16600.0 0.44 200360.0 29600.0 0.8 0.8801 0.9611 3615422 ACon1_001695 OCC1OC(C(OC(=O)c2cc(O)c(O)c(O)c2)C(O)C1O)c3c(O)cc(O)c4c(=O)cc(oc34)c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E16 compound treatment 211040.0 41400.0 1.11 186840.0 16100.0 0.44 1.0911 0.9167 3615425 ACon1_001696 CCCCCC[C@H](O)/C=C/CC1=C(O)CC[C@H](O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E17 mock treatment 153560.0 -16100.0 -0.43 171680.0 914.0 0.02 -0.2863 -0.6653 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E18 mock treatment 163200.0 -6420.0 -0.17 154240.0 -16500.0 -0.45 -0.4378 -0.9136 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E19 compound treatment 170080.0 458.0 0.01 168560.0 -2210.0 -0.06 -0.0336 -0.5505 3558102 ACon1_001697 COc1ccc(cc1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E20 compound treatment 11720.0 -158000.0 -4.22 13120.0 -158000.0 -4.27 -6.0044 -1.0 3558556 ACon1_001698 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E21 compound treatment 180080.0 10500.0 0.28 181560.0 10800.0 0.29 0.4044 0.9998 3615429 ACon1_001699 OC(CCc1ccc(O)c(O)c1)CC(=O)CCc2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E22 compound treatment 178480.0 8860.0 0.24 183560.0 12800.0 0.35 0.4125 0.9829 3559178 ACon1_001700 CC1(CC(O)C2C=COC(OC3OC(CO)C(O)C(O)C3O)C21)OC(=O)/C=C/c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E23 compound treatment 166080.0 -3540.0 -0.09 170440.0 -326.0 -0.01 -0.0732 -0.7696 3615432 ACon1_001701 CC(=O)NC(Cc1c[nH]c2cc(Cl)ccc12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 E24 compound treatment 175680.0 6060.0 0.16 181000.0 10200.0 0.28 0.3105 0.9674 3557371 ACon1_001702 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O)c2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F01 mock treatment 176840.0 7220.0 0.19 187320.0 16600.0 0.45 0.4534 0.9292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F02 mock treatment 184120.0 14500.0 0.39 186800.0 16000.0 0.43 0.5812 0.9984 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F03 compound treatment 189200.0 19600.0 0.52 184800.0 14000.0 0.38 0.639 0.9876 3615435 ACon1_001703 C[C@H](CC/C=C(\C)/C(=O)O)[C@H]1CC(O)[C@@]2(C)C3CC[C@@H]4[C@]5(C[C@@]35CC(O)[C@]12C)CC[C@H](O[C@@H]6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F04 compound treatment 184920.0 15300.0 0.41 172840.0 2070.0 0.06 0.3291 0.7967 3615438 ACon1_001704 CC1OC(OC2C(O)C(O)C(CO)OC2Oc3c(oc4cc(OC5OC(C)C(O)C(O)C5O)cc(O)c4c3=O)c6ccc(O)c(O)c6)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F05 compound treatment 160360.0 -9260.0 -0.25 165800.0 -4970.0 -0.13 -0.2702 -0.9588 3615441 ACon1_001705 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(C)OC(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F06 compound treatment 183120.0 13500.0 0.36 194160.0 23400.0 0.63 0.7031 0.9645 3554104 ACon1_001706 CCC(C)(NC(=O)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(=O)N)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F07 compound treatment 147280.0 -22300.0 -0.6 147800.0 -23000.0 -0.62 -0.8622 -0.9998 3615443 ACon1_001707 COc1cc(O)c2c(=O)oc(/C=C/C(=O)O)cc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F08 compound treatment 15160.0 -154000.0 -4.13 18680.0 -152000.0 -4.12 -5.8329 -1.0 3559796 ACon1_001708 CC(=O)OC1CCC2(C)C(CC[C@@H]3[C@@H]2CCC4(C)C(CCC34O)C5=CC(=O)OC5)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F09 mock treatment 144640.0 -25000.0 -0.67 168840.0 -1930.0 -0.05 -0.5094 -0.76 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F10 mock treatment 156960.0 -12700.0 -0.34 158920.0 -11800.0 -0.32 -0.4663 -0.9996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F11 compound treatment 179400.0 9780.0 0.26 174360.0 3590.0 0.1 0.2537 0.9093 3615449 ACon1_001709 C[C@H](CC/C=C(\C)/C(=O)O)[C@H]1CC[C@@]2(C)C3CC[C@@H]4[C@]5(C[C@@]35CC(O)[C@]12C)CC[C@H](OC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6O)C4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F12 compound treatment 45400.0 -124000.0 -3.32 68080.0 -103000.0 -2.78 -4.3153 -0.9961 3557871 ACon1_001710 OC(=O)[C@]1(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H](OC(=O)/C=C/c3ccc(O)c(O)c3)[C@@H](C1)OC(=O)/C=C/c4ccc(O)c(O)c4)OC(=O)/C=C/c5ccc(O)c(O)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F13 compound treatment 62680.0 -107000.0 -2.86 64520.0 -106000.0 -2.88 -4.0566 -1.0 3553379 ACon1_001711 CC(=O)OC[C@]1(C)[C@H](CC[C@@]2(C)[C@H]1C[C@H](OC(=O)C)[C@@]3(C)Oc4cc(oc(=O)c4[C@H](O)[C@H]23)c5cccnc5)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F14 compound treatment 140600.0 -29000.0 -0.78 146160.0 -24600.0 -0.67 -1.02 -0.9971 3615454 ACon1_001712 CC1CCC2C(C)(C)CCCC2(C)C1(O)C/C=C(\CCOC(=O)C)/C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F15 compound treatment 160840.0 -8780.0 -0.23 182040.0 11300.0 0.31 0.0497 0.1291 3615457 ACon1_001713 CC1CC(=O)C2=C(CCC3(O)C(O)c4c(O)cccc4C(=O)C23)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F16 compound treatment 156320.0 -13300.0 -0.36 183960.0 13200.0 0.36 0.001 0.0019 3615460 ACon1_001714 OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4c(=O)cc(Oc5ccc(O)cc5)oc4c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F17 mock treatment 186400.0 16800.0 0.45 166360.0 -4410.0 -0.12 0.233 0.5018 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F18 mock treatment 147040.0 -22600.0 -0.6 156560.0 -14200.0 -0.38 -0.6991 -0.9762 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F19 compound treatment 140800.0 -28800.0 -0.77 173360.0 2590.0 0.07 -0.4955 -0.64 3559265 ACon1_001715 COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(=C32)C)c4ccoc4)[C@@H]5OC[C@@]6(C)C5[C@]1(C)[C@H](C[C@H]6OC(=O)C)OC(=O)/C(=C/C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F20 compound treatment 153200.0 -16400.0 -0.44 146040.0 -24700.0 -0.67 -0.7839 -0.9791 3615464 ACon1_001716 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H](Cl)[C@@](O)(COC(=O)c4ccccc4)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F21 compound treatment 182440.0 12800.0 0.34 202080.0 31300.0 0.85 0.8419 0.9206 3615468 ACon1_001717 C[C@H](CC/C=C(\C)/C(=O)OC1OC(CO)C(O)C1O)[C@H]2CC(O)[C@@]3(C)C4CC[C@@H]5[C@]6(C[C@@]46CC(O)[C@]23C)CC[C@H](O[C@@H]7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O)C5(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F22 compound treatment 157720.0 -11900.0 -0.32 180800.0 10000.0 0.27 -0.033 -0.0789 3615471 ACon1_001718 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F23 compound treatment 162440.0 -7180.0 -0.19 131600.0 -39200.0 -1.06 -0.8856 -0.8218 3615473 ACon1_001719 CCCCCCCCC#CC#C/C=C/CCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 F24 compound treatment 15320.0 -154000.0 -4.13 14400.0 -156000.0 -4.23 -5.9118 -0.9999 3615477 ACon1_001720 COc1cc(nc(/C=N/O)c1SC)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G01 compound treatment 193480.0 23900.0 0.64 185080.0 14300.0 0.39 0.7253 0.9714 3615480 ACon1_001721 C/C=C/C#CC#C[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)\C=C\CCCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G02 compound treatment 156280.0 -13300.0 -0.36 204800.0 34000.0 0.92 0.3992 0.404 3615484 ACon1_001722 CC1OC(Oc2ccc(cc2)c3cc(=O)c4c(O)cc(OC5OC(CO)C(O)C(O)C5O)cc4o3)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G03 mock treatment 186640.0 17000.0 0.46 170960.0 194.0 0.01 0.3256 0.7152 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G04 mock treatment 156440.0 -13200.0 -0.35 173120.0 2350.0 0.06 -0.2043 -0.5701 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G05 compound treatment 164800.0 -4820.0 -0.13 189000.0 18200.0 0.49 0.2579 0.5054 3552804 ACon1_001723 C[C@@H]1O[C@@H](Oc2ccc(cc2)c3coc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc(O)c4c3=O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G06 compound treatment 164920.0 -4700.0 -0.13 176200.0 5430.0 0.15 0.0151 0.078 3615487 ACon1_001724 OCC1OC(C(OC(=O)c2cc(O)c(O)c(O)c2)C(OC(=O)c3cc(O)c(O)c(O)c3)C1O)c4c(O)cc(O)c(C(=O)c5ccc(O)cc5)c4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G07 compound treatment 79960.0 -89700.0 -2.4 102200.0 -68600.0 -1.86 -3.0085 -0.992 3557601 ACon1_001725 CO[C@@H]1[C@H]2OC(=O)[C@@]3(CCCC(C)(C)C23)c4c(O)c(O)c(cc14)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G08 compound treatment 160400.0 -9220.0 -0.25 149560.0 -21200.0 -0.57 -0.5804 -0.9288 3615490 ACon1_001726 CC1(CO)CC[C@@]2(COC34C=CC5[C@@]6(C)CC[C@H](OC7OCC(O)C(O)C7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)CC2O)C3C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G09 compound treatment 139880.0 -29700.0 -0.8 145320.0 -25400.0 -0.69 -1.0497 -0.9974 3559858 ACon1_001727 CCCCC[C@H](O)[C@H](O)/C=C/[C@@H](O)CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G10 compound treatment 164280.0 -5340.0 -0.14 164120.0 -6650.0 -0.18 -0.2283 -0.9935 3615494 ACon1_001728 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](OC(=O)/C=C/c3ccc(O)cc3)[C@H](O)[C@H]2O)[C@H]4[C@@H]1[C@H](O)C[C@]4(C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G11 compound treatment 170240.0 618.0 0.02 184440.0 13700.0 0.37 0.2735 0.738 3557471 ACon1_001729 COC(=O)c1cccc2oc3cc(C)cc(O)c3c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G12 compound treatment 92200.0 -77400.0 -2.07 102800.0 -68000.0 -1.84 -2.7655 -0.9983 3615499 ACon1_001730 C[C@H]1CCc2cccnc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)c6ccccc6)[C@@H](O)[C@H](OC1=O)[C@]4(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G13 compound treatment 141560.0 -28100.0 -0.75 141800.0 -29000.0 -0.78 -1.0853 -0.9998 3615503 ACon1_001731 CCCCCCCCCCCCCCCC(=O)CCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G14 compound treatment 189880.0 20300.0 0.54 175600.0 4830.0 0.13 0.4757 0.8533 3557525 ACon1_001732 CC1OC(OC2C(O)C(OCCc3ccc(O)c(O)c3)OC(CO)C2OC(=O)/C=C/c4ccc(O)c(O)c4)C(OC5OCC(O)C(O)C5O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G15 compound treatment 171600.0 1980.0 0.05 159720.0 -11000.0 -0.3 -0.174 -0.5731 3615506 ACon1_001733 Cc1ccc(c(O)c1)C(O)(CO)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G16 compound treatment 171760.0 2140.0 0.06 165400.0 -5370.0 -0.15 -0.0623 -0.3989 3615508 ACon1_001734 COc1cc(CCC(O)CC(O)CCc2ccc(O)c(O)c2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G17 compound treatment 151400.0 -18200.0 -0.49 158200.0 -12600.0 -0.34 -0.5852 -0.9845 3615509 ACon1_001735 COc1cccc2C(=O)c3c(C(O)c12)c(SCC(NC(=O)C)C(=O)O)cc4C(O)C(C)CC(=O)c43 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G18 compound treatment 160160.0 -9460.0 -0.25 157560.0 -13200.0 -0.36 -0.4318 -0.9857 3615511 ACon1_001736 CCC(C)C(NC(=O)C(C)(C)NC(=O)C(C)(CC)NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)NC(=O)CCC(NC(=O)C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G19 mock treatment 143880.0 -25700.0 -0.69 153440.0 -17300.0 -0.47 -0.8186 -0.9825 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G20 mock treatment 147480.0 -22100.0 -0.59 178080.0 7310.0 0.2 -0.2788 -0.4464 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G21 compound treatment 171560.0 1940.0 0.05 163560.0 -7210.0 -0.2 -0.1013 -0.5018 2106469 ACon1_001737 COc1ccc2ccc(=O)oc2c1C(O)C(O)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G22 compound treatment 173960.0 4340.0 0.12 193240.0 22500.0 0.61 0.5123 0.8271 3615514 ACon1_001738 COC1=CC(=O)OC1C(O)C(O)C(OC(=O)C)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G23 compound treatment 152840.0 -16800.0 -0.45 183560.0 12800.0 0.35 -0.0725 -0.1279 3615516 ACon1_001739 C[C@@H]1O[C@@H](Oc2ccc(cc2O)C3Oc4cc(O)cc(O)c4C(=O)C3O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 G24 compound treatment 8600.0 -161000.0 -4.31 8200.0 -163000.0 -4.4 -6.1576 -0.9999 3559198 ACon1_001740 C[C@H]1[C@@]2(O)[C@H](CC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@@]32C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)O[C@@]91CCC(C)CO9 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H01 compound treatment 169400.0 -222.0 -0.01 152760.0 -18000.0 -0.49 -0.3489 -0.7157 3615520 ACon1_001741 CC(=O)OC[C@]1(C)[C@@H](CC[C@@]2(C)C3CCC4CC3(CC4(O)CO)CC[C@H]12)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H02 compound treatment 192200.0 22600.0 0.6 189480.0 18700.0 0.51 0.7853 0.9962 3615525 ACon1_001742 COC(=O)[C@H](O)[C@H]1C(C)(C)[C@H](OC(=O)C)[C@]2(O)CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H03 mock treatment 189520.0 19900.0 0.53 191600.0 20800.0 0.56 0.7752 0.9996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H04 mock treatment 160600.0 -9020.0 -0.24 244440.0 73700.0 1.99 1.2397 0.6171 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H05 compound treatment 208640.0 39000.0 1.04 195720.0 25000.0 0.68 1.2157 0.9778 3615530 ACon1_001743 COc1c(O)cc2c(=O)oc3c(OC)c(O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)cc5c(=O)oc1c2c53 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H06 compound treatment 140600.0 -29000.0 -0.78 144000.0 -26800.0 -0.72 -1.0613 -0.9994 3552916 ACon1_001744 C[C@H](/C=C/C=C(\C)/C(=O)N[C@H]1[C@@H](C)[C@@H](C)OC1=O)[C@H]2CC[C@@]3(C)[C@@H]4CCC5[C@]6(C[C@@]46CC[C@]23C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O[C@@H]9O[C@H](CO[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@@H](O)[C@H](O)[C@H]9O[C@@H]%11O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%11O)C5(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H07 compound treatment 92040.0 -77600.0 -2.08 79760.0 -91000.0 -2.46 -3.2095 -0.9964 2060370 ACon1_001745 COc1cc2OCOc2cc1c3coc4c5C=CC(C)(C)Oc5c(OC)cc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H08 compound treatment 16440.0 -153000.0 -4.1 16360.0 -154000.0 -4.18 -5.8531 -1.0 3559797 ACon1_001746 CO[C@H]1C[C@H](OC2CCC3(C)[C@@H](CCC4C3CCC5(C)C(CC(OC(=O)C)C45O)C6=CC(=O)OC6)C2)O[C@@H](C)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H09 compound treatment 160640.0 -8980.0 -0.24 158840.0 -11900.0 -0.32 -0.3982 -0.9894 3615536 ACon1_001747 CC1OC(O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)C[C@@H](O)[C@]6(C)CC[C@]54C)[C@@]2(C)CO)C(OC7OC(C(O)C(O)C7OC8OCC(O)C(O)C8O)C(=O)O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H10 compound treatment 18160.0 -151000.0 -4.05 18920.0 -152000.0 -4.11 -5.7716 -1.0 3559799 ACon1_001748 C[C@@H]1O[C@@H](OC2CCC3(C)[C@@H](CCC4C3CCC5(C)C(CCC45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H11 compound treatment 157520.0 -12100.0 -0.32 166680.0 -4090.0 -0.11 -0.3071 -0.8978 3055308 ACon1_001749 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)C[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H12 compound treatment 170840.0 1220.0 0.03 150880.0 -19900.0 -0.54 -0.3576 -0.6631 3615541 ACon1_001750 CCCC1=CC(=O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H13 compound treatment 187200.0 17600.0 0.47 178240.0 7470.0 0.2 0.4756 0.929 3558466 ACon1_001751 O[C@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H14 compound treatment 164160.0 -5460.0 -0.15 173360.0 2590.0 0.07 -0.0536 -0.331 3615544 ACon1_001752 C[C@@H]1C[C@H]2OC(=O)[C@@]3(C)CCC[C@](C)(C23)[C@]41CCC5(COC(O)C5)O4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H15 compound treatment 152520.0 -17100.0 -0.46 165600.0 -5170.0 -0.14 -0.4224 -0.8829 3615548 ACon1_001753 COc1ccc(CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(=O)C)c3cc(C)oc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H16 compound treatment 88320.0 -81300.0 -2.17 85120.0 -85600.0 -2.32 -3.1773 -0.9995 3615551 ACon1_001754 COc1cc2C[C@@H]3[C@H](COC3=O)[C@@H](OC(=O)C)c4cc5OCOc5cc4-c2c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H17 compound treatment 160880.0 -8740.0 -0.23 163800.0 -6970.0 -0.19 -0.2987 -0.9943 3615554 ACon1_001755 CC1OC(OCC2OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CCC6=C5CC[C@]7(CCC(C)(C)CC67)C(=O)OC8OC(CO)C(O)C(O)C8O)C3(C)C)C(O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H18 compound treatment 185640.0 16000.0 0.43 171600.0 834.0 0.02 0.3189 0.7433 3615558 ACon1_001756 C[C@@H]1O[C@H]2Oc3c(oc4cc(O)c(c(O)c4c3=O)-c5cc(/C=C/C(=O)OC[C@H]6O[C@@H](O[C@H]([C@H]1O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]6O)ccc5O)c7ccc(O)c(O)c7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H19 mock treatment 140040.0 -29600.0 -0.79 187160.0 16400.0 0.44 -0.2457 -0.2708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H20 mock treatment 152600.0 -17000.0 -0.46 162040.0 -8730.0 -0.24 -0.489 -0.9533 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H21 compound treatment 165200.0 -4420.0 -0.12 158640.0 -12100.0 -0.33 -0.3158 -0.9049 3615562 ACon1_001757 CC1CCC2C(C)(C=O)C(O)CCC2(C)C1CC/C(=C\C(=O)O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H22 compound treatment 181320.0 11700.0 0.31 160120.0 -10600.0 -0.29 0.0175 0.0411 3558771 ACon1_001758 CC1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C)C(O)C(O)C6O)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H23 compound treatment 159680.0 -9940.0 -0.27 172080.0 1310.0 0.04 -0.1629 -0.6071 3615567 ACon1_001759 COc1ccc2c3[C@H](OCC=C(C)C)[C@]4(O)N([C@H]5CC(C)(C)OO[C@H](C=C(C)C)n(c53)c2c1)C(=O)[C@@H]6CCCN6C4=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 H24 compound treatment 164720.0 -4900.0 -0.13 166800.0 -3970.0 -0.11 -0.1686 -0.9951 1055133 ACon1_001760 COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I01 compound treatment 150280.0 -19300.0 -0.52 132280.0 -38500.0 -1.04 -1.1026 -0.9478 3615574 ACon1_001761 CNC1CCC23CC34CCC5(C)C(C(C)N(C)C(=O)C)C(O)CC5(C)C4CCC2C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I02 compound treatment 204040.0 34400.0 0.92 219640.0 48900.0 1.32 1.5866 0.9843 3615576 ACon1_001762 C[C@@H]1O[C@@H](OC(=O)[C@@]23CCC(C)(C)CC3C4=CCC5[C@@]6(C)C[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]2O)[C@@H](O[C@@H]8OC[C@@H](O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O[C@@H]%10OC[C@@H](O)[C@@H](O)[C@@H]%10O)[C@@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I03 compound treatment 164280.0 -5340.0 -0.14 165600.0 -5170.0 -0.14 -0.1999 -0.9999 3555361 ACon1_001763 COCC1C(=O)O[C@H]2C[C@@]3(C)OC(=O)/C(=C/C)/[C@]43CC[C@@](C)(O)CC(=O)[C@]12O4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I04 compound treatment 173160.0 3540.0 0.09 164480.0 -6290.0 -0.17 -0.0534 -0.2743 3615580 ACon1_001764 CC1(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)CC[C@]2(CC1O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I05 mock treatment 151760.0 -17900.0 -0.48 154760.0 -16000.0 -0.43 -0.6442 -0.9988 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I06 mock treatment 144080.0 -25500.0 -0.68 156640.0 -14100.0 -0.38 -0.7535 -0.9624 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I07 compound treatment 63000.0 -107000.0 -2.85 48000.0 -123000.0 -3.32 -4.3668 -0.9971 3615585 ACon1_001765 O[C@@H]1[C@@H](COC(=O)/C=C/c2ccc(O)cc2)O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H]1OC(=O)/C=C/c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I08 compound treatment 161120.0 -8500.0 -0.23 157720.0 -13000.0 -0.35 -0.4105 -0.9773 3615588 ACon1_001766 C[C@H]1[C@H](O)C=CC2=CC(=O)[C@@](O)(C[C@]12C)C(=C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I09 compound treatment 146840.0 -22800.0 -0.61 147880.0 -22900.0 -0.62 -0.869 -1.0 3554244 ACon1_001767 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCC(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I10 compound treatment 93800.0 -75800.0 -2.03 101440.0 -69300.0 -1.88 -2.7612 -0.9993 3615592 ACon1_001768 C[C@H]1CCc2ccncc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)C)[C@@H](O)[C@H](O)[C@]4(C)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I11 compound treatment 169120.0 -502.0 -0.01 168080.0 -2690.0 -0.07 -0.0609 -0.8237 3555007 ACon1_001769 COc1cc(OC)c2c(O)c3C(=O)CC(C)(O)Oc3cc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I12 compound treatment 189040.0 19400.0 0.52 198440.0 27700.0 0.75 0.897 0.984 3615597 ACon1_001770 COC1OC(=O)C(CCC2(C)C(C)CCC3(C)C2CC(O)C(O)C43CO4)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I13 compound treatment 163520.0 -6100.0 -0.16 159400.0 -11400.0 -0.31 -0.333 -0.956 3615600 ACon1_001771 COc1ccc(OC2OC(COC3OCC(O)C(O)C3O)C(O)C(O)C2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I14 compound treatment 183200.0 13600.0 0.36 199960.0 29200.0 0.79 0.8157 0.9378 3615602 ACon1_001772 COc1cc(O)c-2c(CCc3cc(O)c(OC)cc32)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I15 compound treatment 187920.0 18300.0 0.49 198000.0 27200.0 0.74 0.8674 0.9802 3615604 ACon1_001773 O[C@@H]1[C@@H](Oc2c([C@H]3C[C@@H](Oc4cc(O)ccc34)c5ccc(O)c(O)c5)c(O)cc(O)c2C1=O)c6ccc(O)c(O)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I16 compound treatment 160560.0 -9060.0 -0.24 151920.0 -18800.0 -0.51 -0.5322 -0.9421 3615608 ACon1_001774 CC1(C)C2CC[C@]3(C[C@H]4CC[C@H]3[C@@]52CC[C@@]1(O)OC5)CC4(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I17 compound treatment 159320.0 -10300.0 -0.28 163520.0 -7250.0 -0.2 -0.3336 -0.9861 3615612 ACon1_001775 OC[C@H]1O[C@@H](Oc2ccc(C(=O)CCc3ccc(O)cc3)c(O)c2)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I18 compound treatment 171560.0 1940.0 0.05 186000.0 15200.0 0.41 0.3283 0.7898 3558031 ACon1_001776 COc1ccc(/C=C/C(=O)OC2C(C)OC(OC3C4OC4(CO)C5C3C=COC5OC6OC(CO)C(O)C(O)C6O)C(O)C2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I19 compound treatment 88840.0 -80800.0 -2.16 102840.0 -67900.0 -1.84 -2.8282 -0.9968 3554120 ACon1_001777 CCC(C)[C@@H]1N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I20 compound treatment 99720.0 -69900.0 -1.87 145920.0 -24800.0 -0.67 -1.7978 -0.9047 3559162 ACon1_001778 Oc1ccc(cc1)[C@H]2[C@H]([C@@H]3[C@H](c4ccc(O)cc4)c5ccc(O)cc5OC3=O)C(=O)Oc6cc(O)ccc26 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I21 mock treatment 150760.0 -18900.0 -0.5 184120.0 13400.0 0.36 -0.1011 -0.1629 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I22 mock treatment 155560.0 -14100.0 -0.38 233320.0 62600.0 1.69 0.9315 0.537 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I23 compound treatment 186760.0 17100.0 0.46 176480.0 5710.0 0.15 0.4335 0.8961 3615618 ACon1_001779 COc1cc(CCC(=O)O)oc(=O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 I24 compound treatment 9320.0 -160000.0 -4.29 9200.0 -162000.0 -4.37 -6.1249 -1.0 3615620 ACon1_001780 CC(C)C(=C)CCC(C)[C@H]1CC=C2C3=C([C@@H](O)[C@H](OC(=O)C)[C@]12C)[C@@]4(C)C[C@@H](O)[C@H](O)C(C)(C)C4CC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J01 compound treatment 196200.0 26600.0 0.71 218880.0 48100.0 1.3 1.4238 0.9594 3615624 ACon1_001781 CC(=CCc1c(O)ccc2cc(O)c(=O)oc12)COC3OC(CO)C(O)C(O)C3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J02 compound treatment 209400.0 39800.0 1.06 198120.0 27400.0 0.74 1.276 0.9843 3615625 ACon1_001782 CC1OC(OC2C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC65C)C(=O)OC8OC(CO)C(OC9OCC(OC%10OCC(O)C(O)C%10O)C(O)C9O)C(O)C8O)C3(C)C)OC(C2O)C(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J03 compound treatment 193280.0 23700.0 0.63 198240.0 27500.0 0.74 0.9734 0.9968 3615627 ACon1_001783 CC1(CO)CC(O)[C@@]2(CCC34CC4(C=CC5[C@@]6(C)C[C@@H](O)[C@H](O)C(CO)(CO)C6CC[C@]53C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J04 compound treatment 100920.0 -68700.0 -1.84 94240.0 -76500.0 -2.07 -2.7644 -0.9982 3558573 ACon1_001784 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](O)C(C)(C)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J05 mock treatment 157400.0 -12200.0 -0.33 174160.0 3390.0 0.09 -0.1662 -0.4894 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J06 mock treatment 143360.0 -26300.0 -0.7 164600.0 -6170.0 -0.17 -0.6148 -0.8514 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J07 compound treatment 176360.0 6740.0 0.18 141040.0 -29700.0 -0.8 -0.4416 -0.5355 3615632 ACon1_001785 COc1cc(O)cc(C)c1C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(OC)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J08 compound treatment 22960.0 -147000.0 -3.92 21000.0 -150000.0 -4.05 -5.641 -0.9999 3559809 ACon1_001786 CO[C@H]1[C@@H](O)[C@@H](C)O[C@@H](OC2CCC3(C)C(CC[C@@H]4[C@@H]3CCC5(C)C(C(O)CC45O)C6=CC(=O)OC6)C2)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J09 compound treatment 239800.0 70200.0 1.88 196040.0 25300.0 0.68 1.8112 0.9065 3557709 ACon1_001787 COc1cc(cc(OC)c1O)C2C(COC3OC(CO)C(O)C(O)C3O)C(CO)Cc4cc(OC)c(O)c(OC)c24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J10 compound treatment 168800.0 -822.0 -0.02 160760.0 -10000.0 -0.27 -0.2071 -0.762 3559803 ACon1_001788 CC12CC[C@H]3C(CCC4(O)CC(O)CCC34O)C2(O)CCC1C5=CC(=O)OC5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J11 compound treatment 77800.0 -91800.0 -2.46 72120.0 -98600.0 -2.67 -3.6251 -0.9991 3559166 ACon1_001789 COc1cc2OCOc2cc1c3coc4c5C=CC(C)(C)Oc5ccc4c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J12 compound treatment 146200.0 -23400.0 -0.63 142920.0 -27800.0 -0.75 -0.9761 -0.9958 3615637 ACon1_001790 O[C@@H]1CO[C@@H](OC(CCc2ccc(O)cc2)CC(=O)CCc3ccc(O)cc3)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J13 compound treatment 139720.0 -29900.0 -0.8 143560.0 -27200.0 -0.74 -1.0864 -0.9992 3557350 ACon1_001791 C[C@@H]1CC(=O)c2c(C1)ccc3C(=O)c4c(O)cccc4C(=O)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J14 compound treatment 16960.0 -153000.0 -4.08 23720.0 -147000.0 -3.98 -5.7024 -0.9999 3615642 ACon1_001792 CC1(CCCC2(C)C3CCC(=C)C(C=C)C3CCC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J15 compound treatment 169840.0 218.0 0.01 167240.0 -3530.0 -0.1 -0.0634 -0.6626 3615644 ACon1_001793 Cc1cc2c(CO)cc(SCC(O)C(=O)O)cc2o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J16 compound treatment 193960.0 24300.0 0.65 161720.0 -9050.0 -0.24 0.2872 0.4129 3615646 ACon1_001794 OCC1OC(Oc2c(O)cccc2COC(=O)C3(O)C=CCCC3=O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J17 compound treatment 168600.0 -1020.0 -0.03 175160.0 4390.0 0.12 0.0648 0.5308 3615649 ACon1_001795 OC(CNC(=O)/C=C/c1ccc(O)cc1)c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J18 compound treatment 159400.0 -10200.0 -0.27 147320.0 -23400.0 -0.63 -0.6422 -0.9292 3615653 ACon1_001796 C[C@@H]1O[C@H]2Oc3c(oc4cc(O)c(c(O)c4c3=O)-c5cc(/C=C/C(=O)OC[C@H]6O[C@@H](O[C@H]([C@H]1O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]6O)ccc5O)c7ccc(O)cc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J19 compound treatment 164880.0 -4740.0 -0.13 157880.0 -12900.0 -0.35 -0.3364 -0.9062 3615657 ACon1_001797 COCC1OC(OC(C)(C)C(O)CCC2(C)C/C(=C/3\CCC4C3(C)CC(O)C5OC(CCC45C)C(C)(C)OC6OC(COC)C(O)C(O)C6NC(=O)C)/CCC2O)C(NC(=O)C)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J20 compound treatment 159440.0 -10200.0 -0.27 203920.0 33200.0 0.9 0.4421 0.4713 3615662 ACon1_001798 CC1OC(Oc2cc(O)c3c(=O)cc(oc3c2C4OC(CO)C(O)C(O)C4O)c5ccc(O)cc5)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J21 mock treatment 181280.0 11700.0 0.31 173920.0 3150.0 0.09 0.2809 0.8687 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J22 mock treatment 163880.0 -5740.0 -0.15 157080.0 -13700.0 -0.37 -0.3706 -0.924 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J23 compound treatment 21440.0 -148000.0 -3.96 23080.0 -148000.0 -4.0 -5.6299 -1.0 3615664 ACon1_001799 CC(C)CC1NC(=O)C(CC(C)C)N(O[C@@H]2O[C@H](COC(=O)CCC(=O)O)[C@@H](O)[C@H](O)[C@H]2O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 J24 compound treatment 227160.0 57500.0 1.54 192200.0 21400.0 0.58 1.4986 0.9111 3615667 ACon1_001800 COc1ccc2nccc(C(O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K01 compound treatment 189800.0 20200.0 0.54 169280.0 -1490.0 -0.04 0.3532 0.6526 3615669 ACon1_001801 CCN1CC2(COC)CCC(O)C3(C4CC5C(O)C4C(O)(CC5OC)C6C(OC)C32)C61 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K02 compound treatment 175280.0 5660.0 0.15 179760.0 8990.0 0.24 0.2792 0.9738 3615671 ACon1_001802 CC1=CCC(CC1)C(C)(C)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](COC(=O)c4cc(O)c(O)c(O)c4)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K03 compound treatment 195280.0 25700.0 0.69 159240.0 -11500.0 -0.31 0.2647 0.351 3558951 ACon1_001803 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K04 compound treatment 182560.0 12900.0 0.35 157680.0 -13100.0 -0.35 -0.0058 -0.0117 3615676 ACon1_001804 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3ccc(CC=C)cc3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K05 compound treatment 162400.0 -7220.0 -0.19 148000.0 -22800.0 -0.62 -0.5724 -0.8862 3555002 ACon1_001805 COc1cc(oc(=O)c1)[C@H](Cc2ccccc2)NC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K06 compound treatment 142360.0 -27300.0 -0.73 143600.0 -27200.0 -0.74 -1.0357 -1.0 3615680 ACon1_001806 C/C(=C/CCC(CO)C1CCC2(C)C3CCC4C5(CC35CCC12C)CCC(OC6OC(CO)C(O)C(O)C6O)C4(C)C)/COC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K07 mock treatment 153720.0 -15900.0 -0.43 149560.0 -21200.0 -0.57 -0.7067 -0.9891 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K08 mock treatment 153200.0 -16400.0 -0.44 142080.0 -28700.0 -0.78 -0.8597 -0.9636 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K09 compound treatment 168160.0 -1460.0 -0.04 178440.0 7670.0 0.21 0.1193 0.5641 3553885 ACon1_001807 CC1(CC(=O)O)CCC2(O1)C(=CCC3C(C)(C)C(O)CCC32C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K10 compound treatment 158520.0 -11100.0 -0.3 162280.0 -8490.0 -0.23 -0.3724 -0.992 3615685 ACon1_001808 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)OC(=O)C)OC(=O)/C=C\c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K11 compound treatment 177440.0 7820.0 0.21 194520.0 23800.0 0.64 0.6026 0.8911 3558491 ACon1_001809 COc1cc(ccc1O)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K12 compound treatment 157640.0 -12000.0 -0.32 154840.0 -15900.0 -0.43 -0.5315 -0.9893 3615689 ACon1_001810 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)O)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K13 compound treatment 160760.0 -8860.0 -0.24 164560.0 -6210.0 -0.17 -0.2864 -0.9858 3557476 ACon1_001811 OCC1OC(C(O)C(O)C1O)c2c(O)c(C3OCC(O)C(O)C3O)c4oc(cc(=O)c4c2O)c5ccc(O)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K14 compound treatment 163040.0 -6580.0 -0.18 165960.0 -4810.0 -0.13 -0.2165 -0.9889 3615693 ACon1_001812 OC[C@H]1O[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K15 mock treatment 183240.0 13600.0 0.36 162680.0 -8090.0 -0.22 0.1028 0.2419 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K16 mock treatment 155480.0 -14100.0 -0.38 143840.0 -26900.0 -0.73 -0.7829 -0.9533 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K17 compound treatment 171600.0 1980.0 0.05 166360.0 -4410.0 -0.12 -0.0469 -0.3596 3615697 ACon1_001813 CC(=CCc1cc(CC(N)C(=O)O)ccc1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K18 compound treatment 149920.0 -19700.0 -0.53 162240.0 -8530.0 -0.23 -0.5359 -0.9314 3615699 ACon1_001814 Cc1cc2C(=O)c3cc(O)cc(O)c3C(=O)c2c(O)c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K19 compound treatment 183240.0 13600.0 0.36 169680.0 -1090.0 -0.03 0.2368 0.6479 1012497 ACon1_001815 NC(Cc1c[nH]c2ccccc12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K20 compound treatment 175280.0 5660.0 0.15 162280.0 -8490.0 -0.23 -0.0554 -0.2015 3558198 ACon1_001816 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccc(O)c(O)c6)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K21 compound treatment 165240.0 -4380.0 -0.12 171080.0 314.0 0.01 -0.0769 -0.6541 3615703 ACon1_001817 COC(CCc1ccc(O)c(O)c1)CC(=O)CCc2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K22 compound treatment 197760.0 28100.0 0.75 192760.0 22000.0 0.6 0.9532 0.9933 3615705 ACon1_001818 C/C=C/C=C/C(=O)O[C@@H]1C=C(CO)[C@](O)(CO)[C@@]2(C)CCCC(C)(C)[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K23 mock treatment 164080.0 -5540.0 -0.15 209360.0 38600.0 1.04 0.634 0.6008 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 K24 mock treatment 176960.0 7340.0 0.2 171640.0 874.0 0.02 0.1555 0.7867 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L01 compound treatment 218440.0 48800.0 1.31 177160.0 6390.0 0.17 1.0458 0.7939 3557532 ACon1_001819 C[C@@H](O)/C=C/[C@@]1(O)C(C)(C)C[C@@H](C[C@@]1(C)O)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L02 compound treatment 198080.0 28500.0 0.76 242200.0 71400.0 1.93 1.9057 0.917 3615710 ACon1_001820 COc1c(O)c2c(=O)c(O)c(oc2cc1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L03 compound treatment 14440.0 -155000.0 -4.15 12280.0 -158000.0 -4.29 -5.9691 -0.9999 3615714 ACon1_001821 COc1cc(O)c(C(=O)CCc2ccccc2)c(O)c1Cc3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L04 compound treatment 190320.0 20700.0 0.55 161480.0 -9290.0 -0.25 0.2137 0.3515 3615716 ACon1_001822 C[C@@]1([C@H](O)CC[C@]2(C)C3CCC(=C)[C@H](C=C)[C@@H]3CC[C@@]12O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L05 compound treatment 199280.0 29700.0 0.79 205640.0 34900.0 0.94 1.2286 0.9963 3615720 ACon1_001823 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C(O)C=C3CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L06 compound treatment 15720.0 -154000.0 -4.12 13440.0 -157000.0 -4.26 -5.9227 -0.9999 3557431 ACon1_001824 CC(C)CCCCCCCCC/C=C/C(=O)NC1C(O)C(O)C(CC(O)C2OC(C(O)C2O)n3ccc(=O)[nH]c3=O)OC1OC4OC(CO)C(O)C(O)C4NC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L07 mock treatment 171280.0 1660.0 0.04 153040.0 -17700.0 -0.48 -0.308 -0.639 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L08 mock treatment 162160.0 -7460.0 -0.2 156840.0 -13900.0 -0.38 -0.4077 -0.9558 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L09 compound treatment 157040.0 -12600.0 -0.34 150080.0 -20700.0 -0.56 -0.634 -0.9703 3615722 ACon1_001825 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(O)C5(C)C(O)(CCC54O)C(=O)C)C2)OC(C)C1OC6CC(OC)C(OC7OC(C)C(O)C(OC)C7O)C(C)O6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L10 compound treatment 23160.0 -146000.0 -3.92 20440.0 -150000.0 -4.07 -5.6479 -0.9998 3559811 ACon1_001826 C[C@H]1O[C@H](C[C@H](OC(=O)C)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)OC4CC(O)C5(C)C(CC[C@@H]6[C@@H]5CCC7(C)C(CCC67O)C8=CC(=O)OC8)C4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L11 compound treatment 175360.0 5740.0 0.15 143240.0 -27500.0 -0.75 -0.4184 -0.5499 3615725 ACon1_001827 COC(=O)C(NC(=O)c1cccc(NC=O)c1O)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L12 compound treatment 188160.0 18500.0 0.5 164640.0 -6130.0 -0.17 0.2334 0.4463 3615727 ACon1_001828 Cc1cc2C(=O)OC(c2c(O)c1)c3c(O)cccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L13 compound treatment 171400.0 1780.0 0.05 158040.0 -12700.0 -0.34 -0.21 -0.6038 3557341 ACon1_001829 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)O[C@@]91CC[C@@](C)(CO)O9 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L14 compound treatment 44920.0 -125000.0 -3.34 33200.0 -138000.0 -3.72 -4.9921 -0.9985 3615729 ACon1_001830 COC1CC(OC2C(C)OC(CC2OC)OC3C(C)OC(CC3OC)OC4C(C)OCC(OC5C(O)C(O[C@H]6CC[C@]7(C)C8CC(OC(=O)c9ccccc9)[C@]%10(C)[C@@](O)(CC[C@]%10(O)[C@]8(O)CC=C7C6)C(=O)C)OC(CO)C5OC%11OC(CO)C(O)C(O)C%11O)C4OC)OC(C)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L15 mock treatment 190000.0 20400.0 0.55 149640.0 -21100.0 -0.57 -0.019 -0.024 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L16 mock treatment 167000.0 -2620.0 -0.07 141600.0 -29200.0 -0.79 -0.6079 -0.7669 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L17 compound treatment 220320.0 50700.0 1.36 195160.0 24400.0 0.66 1.4259 0.9453 3559248 ACon1_001831 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](CO)O[C@H]2OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@@](C)(CO)C7[C@H](O)C[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](O)[C@H](O)[C@H]1O[C@@H]9OC[C@@H](O)[C@H](O[C@H]%10OC[C@](O)(CO)[C@H]%10O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L18 compound treatment 215920.0 46300.0 1.24 200200.0 29400.0 0.8 1.4392 0.9773 3615734 ACon1_001832 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(COC(=O)c6cc(O)c(O)c(O)c6)C5[C@H](O)C[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L19 compound treatment 184640.0 15000.0 0.4 167320.0 -3450.0 -0.09 0.2181 0.5288 3615738 ACon1_001833 C/C(=C\CC(C)(C)CCC(=O)c1ccoc1)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L20 compound treatment 140880.0 -28700.0 -0.77 160000.0 -10800.0 -0.29 -0.7497 -0.9118 3615742 ACon1_001834 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(COC(=O)c5ccccc5)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L21 compound treatment 28120.0 -142000.0 -3.79 23320.0 -147000.0 -3.99 -5.499 -0.9996 3559153 ACon1_001835 CC/C=C\C[C@H]1[C@@H](CCCCCCCC(=O)O)C=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L22 compound treatment 128480.0 -41100.0 -1.1 137640.0 -33100.0 -0.9 -1.4123 -0.9948 3615746 ACon1_001836 Oc1ccc2C3Oc4cc5OCOc5cc4C3COc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L23 mock treatment 188440.0 18800.0 0.5 193360.0 22600.0 0.61 0.7885 0.9953 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 L24 mock treatment 173480.0 3860.0 0.1 170760.0 -5.9 0.0 0.0729 0.706 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M01 compound treatment 188640.0 19000.0 0.51 173320.0 2550.0 0.07 0.4086 0.7959 3615749 ACon1_001837 COc1ccc2[nH]c3C4CC/5C(CO)C(Cc3c2c1)N4C\C5=C\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M02 compound treatment 64960.0 -105000.0 -2.8 52680.0 -118000.0 -3.2 -4.2401 -0.9978 3615752 ACon1_001838 C[C@@H]1O[C@@H](OC(=O)[C@@]23CCC(C)(C)CC3C4=CCC5[C@@]6(C)C[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]2O)[C@@H](O[C@@H]8OC[C@@H](O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O[C@@H]%10OC[C@@H](O)[C@H](O)[C@H]%10O)[C@@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M03 compound treatment 192160.0 22500.0 0.6 171200.0 434.0 0.01 0.4346 0.7208 3557747 ACon1_001839 C/C(=C\C(=O)O)/CCC1C(C)(O)CCC2C(C)(CO)CCCC12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M04 compound treatment 194400.0 24800.0 0.66 159880.0 -10900.0 -0.29 0.2603 0.3588 3615755 ACon1_001840 CCC(C)CCC(O)C1CC(CO)OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M05 compound treatment 150000.0 -19600.0 -0.52 136960.0 -33800.0 -0.92 -1.0183 -0.9652 3554765 ACon1_001841 COc1c(O)c2c(CCC3C(C)(C)[C@@H]4CC[C@@]32C(=O)O4)cc1C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M06 compound treatment 176080.0 6460.0 0.17 181120.0 10400.0 0.28 0.3204 0.973 3615758 ACon1_001842 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3C=C(CO)[C@@H]4[C@H]3C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H]2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M07 compound treatment 163640.0 -5980.0 -0.16 167800.0 -2970.0 -0.08 -0.1699 -0.9491 812 ACon1_001843 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M08 compound treatment 194040.0 24400.0 0.65 155920.0 -14800.0 -0.4 0.1777 0.2316 3615763 ACon1_001844 CCCCCC/C=C\[N+](=N[C@@H](COC)[C@H](C)O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M09 mock treatment 177560.0 7940.0 0.21 160360.0 -10400.0 -0.28 -0.0491 -0.1391 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M10 mock treatment 165640.0 -3980.0 -0.11 171640.0 874.0 0.02 -0.0586 -0.5369 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M11 compound treatment 185680.0 16100.0 0.43 161880.0 -8890.0 -0.24 0.1336 0.2714 3615766 ACon1_001845 CCC/C=C/C=C/C1CC(O)C(O)C1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M12 compound treatment 175160.0 5540.0 0.15 177280.0 6510.0 0.18 0.2294 0.9962 3615770 ACon1_001846 CC1CC(=O)CC(C)(C)C1(O)/C=C/C(CO)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M13 mock treatment 168920.0 -702.0 -0.02 165800.0 -4970.0 -0.13 -0.1083 -0.7981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M14 mock treatment 180880.0 11300.0 0.3 181440.0 10700.0 0.29 0.4173 0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M15 compound treatment 215000.0 45400.0 1.21 188560.0 17800.0 0.48 1.1989 0.9181 3615774 ACon1_001847 OC1Cc2c(OC1c3ccc(O)c(O)c3)cc(O)c4C(CC(Oc24)c5ccc(O)c(O)c5)c6ccc(O)c(O)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M16 compound treatment 178240.0 8620.0 0.23 164240.0 -6530.0 -0.18 0.0381 0.1311 3615776 ACon1_001848 COc1cc(CCC(O)CC(=O)CCc2ccc(O)cc2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M17 compound treatment 159800.0 -9820.0 -0.26 166640.0 -4130.0 -0.11 -0.2648 -0.9274 3615778 ACon1_001849 COc1c(O)c(C(=O)CCc2ccccc2)c(OC)c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M18 compound treatment 173640.0 4020.0 0.11 176520.0 5750.0 0.16 0.1862 0.9836 3615780 ACon1_001850 CC1(C)CC2C3=CCC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6O)C(C)(C)C5CCC4(C)C3(C)CC(O)C2(CC1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M19 compound treatment 146880.0 -22700.0 -0.61 135440.0 -35300.0 -0.96 -1.1064 -0.9761 3615782 ACon1_001851 CC(C)(C=C)[C@]12C[C@@H]3N([C@@H]2Nc4ccccc41)C(=O)c5ccccc5NC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M20 compound treatment 147040.0 -22600.0 -0.6 143360.0 -27400.0 -0.74 -0.9518 -0.9948 3615785 ACon1_001852 CC1=CC2OC3[C@H](O)C[C@@](C)([C@@]43CO4)[C@@]2(CO)CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M21 compound treatment 94040.0 -75600.0 -2.02 100720.0 -70000.0 -1.9 -2.7705 -0.9995 3615790 ACon1_001853 CC1C[C@]2(CC3C(C)(C)[C@@]4(C[C@]53CN2C1=O)C(=O)Nc6c4ccc7OC(C)(C)CC(=O)c67)C(=O)N5C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M22 compound treatment 154840.0 -14800.0 -0.4 117360.0 -53400.0 -1.45 -1.3019 -0.8686 3557357 ACon1_001854 CC(C)[C@@H](OC(=O)C)c1nc2ccccc2c(=O)n1[C@@H]3C[C@]4(OC3=O)[C@H]5N(O)[C@@H](C)C(=O)N5c6ccccc64 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M23 compound treatment 177240.0 7620.0 0.2 159720.0 -11000.0 -0.3 -0.0674 -0.1862 3559013 ACon1_001855 Oc1ccc(cc1)[C@@H]2Oc3cc(O)cc(O)c3C(=O)[C@H]2c4c(O)cc(O)c5c(=O)cc(oc45)c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 M24 compound treatment 179160.0 9540.0 0.26 157640.0 -13100.0 -0.36 -0.0709 -0.162 3559205 ACon1_001856 COc1cc(cc(OC)c1OC)[C@H]2OC[C@@H]3[C@@H](OC[C@H]23)c4cc(OC)c(OC)c(OC)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N01 compound treatment 194080.0 24500.0 0.65 192360.0 21600.0 0.58 0.876 0.9984 3615795 ACon1_001857 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(O)C5(C)C(O)(CCC54O)C(C)O)C2)OC(C)C1OC6CC(OC)C(OC7OC(C)C(O)C(OC)C7O)C(C)O6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N02 compound treatment 213880.0 44300.0 1.18 173280.0 2510.0 0.07 0.8852 0.7465 3615797 ACon1_001858 C[C@@H]1OC(=O)[C@]2(C(=C)[C@@]3(C)OC(=O)[C@@]12O)C4(C)CC[C@]5(C=CC(=O)OC5(C)C)C(=C4[C@H]3OC(=O)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N03 compound treatment 195000.0 25400.0 0.68 163440.0 -7330.0 -0.2 0.3398 0.4804 3615800 ACon1_001859 C/C=C/C1C2OC3=C(C(=O)OC3(C)O)C(=O)C1(C)C4CC(O)C(C)CC4C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N04 compound treatment 193040.0 23400.0 0.63 201960.0 31200.0 0.84 1.0401 0.9892 3615805 ACon1_001860 COc1cc(ccc1O)[C@@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)Oc3ccc(/C=C/CO)cc3OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N05 compound treatment 17320.0 -152000.0 -4.07 38920.0 -132000.0 -3.57 -5.4046 -0.9978 3615808 ACon1_001861 C/C(=C\Cc1c(O)ccc2ccc(=O)oc12)/CO[C@@H]3O[C@H](COC(=O)CC(=O)OC[C@H]4O[C@@H](OC(C)(C)C5Cc6cc7cc(O)c(=O)oc7cc6O5)[C@H](O)[C@@H](O)[C@@H]4O)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N06 compound treatment 170000.0 378.0 0.01 169000.0 -1770.0 -0.05 -0.0267 -0.5454 3557396 ACon1_001862 COC(=O)c1cc(C)cc(OC)c1C2=C(O)C(=O)c3c(O)cccc3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N07 compound treatment 187160.0 17500.0 0.47 169520.0 -1250.0 -0.03 0.3079 0.6546 3615812 ACon1_001863 COc1cc-2c(CCc3cc(O)c(O)cc32)c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N08 compound treatment 186800.0 17200.0 0.46 154480.0 -16300.0 -0.44 0.0131 0.0206 3557452 ACon1_001864 C[C@@]12CCC3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CC[C@]1(O)C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N09 mock treatment 168720.0 -902.0 -0.02 150640.0 -20100.0 -0.54 -0.4023 -0.7377 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N10 mock treatment 174480.0 4860.0 0.13 152560.0 -18200.0 -0.49 -0.2566 -0.5035 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N11 compound treatment 166960.0 -2660.0 -0.07 153680.0 -17100.0 -0.46 -0.3774 -0.8065 3615814 ACon1_001865 CC1CC(=O)C2=C(CCC34OC42C(=O)c5cccc(O)c5C3O)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N12 compound treatment 182000.0 12400.0 0.33 165000.0 -5770.0 -0.16 0.1237 0.3381 3554299 ACon1_001866 CCCCCCCCCC[C@H](C(=O)O)[C@@](O)(CCC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N13 mock treatment 159000.0 -10600.0 -0.28 174760.0 3990.0 0.11 -0.1244 -0.4094 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N14 mock treatment 195920.0 26300.0 0.7 159440.0 -11300.0 -0.31 0.2806 0.3657 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N15 compound treatment 233160.0 63500.0 1.7 174400.0 3630.0 0.1 1.2713 0.7468 2121 ACon1_001867 Oc1ccc(cc1)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N16 compound treatment 182680.0 13100.0 0.35 160560.0 -10200.0 -0.28 0.0516 0.1159 3615816 ACon1_001868 CC(C1CC(O)C(C)(C)O1)C2CC[C@@]3(C)C4CC[C@H]5C(C)C(CC[C@]65C[C@@]46CC[C@]23C)OC7OC(COC(=O)C)C(OC8OC(CO)C(OC9OC(CO)C(O)C(O)C9O)C(OC%10OC(C)C(O)C(O)C%10O)C8O)C(OC(=O)C)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N17 compound treatment 223080.0 53500.0 1.43 163200.0 -7570.0 -0.2 0.8663 0.5997 3615822 ACon1_001869 CC12CC(OC(=O)C2CCC3(C)C1C4OC(=O)C3(O)C5OC54)c6ccoc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N18 compound treatment 178560.0 8940.0 0.24 144280.0 -26500.0 -0.72 -0.338 -0.4471 3615824 ACon1_001870 C/C(=C\Cc1c(O)cc2oc(C)cc(=O)c2c1O)/CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N19 compound treatment 182400.0 12800.0 0.34 182720.0 12000.0 0.32 0.4705 0.9996 3615829 ACon1_001871 COCC1OC(OC(C)(C)C2CCC3(C)C4CC/C(=C\5/CCC(O)C(C)(CCC(O)C(C)(C)O)C5)/C4(C)CC(O)C3O2)C(NC(=O)C)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N20 compound treatment 164120.0 -5500.0 -0.15 185000.0 14200.0 0.39 0.1684 0.4083 3615833 ACon1_001872 CCCCCC1CC(CC(=O)O1)OC2OC(CO)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N21 compound treatment 184960.0 15300.0 0.41 156920.0 -13800.0 -0.37 0.0251 0.0451 3554654 ACon1_001873 COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(=C32)C)c4ccoc4)[C@H](O)C5[C@@](C)(C=CC(=O)[C@]15C)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N22 compound treatment 180520.0 10900.0 0.29 169600.0 -1170.0 -0.03 0.1838 0.6269 3558591 ACon1_001874 CC(=CCC[C@@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)C=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N23 compound treatment 160280.0 -9340.0 -0.25 136640.0 -34100.0 -0.92 -0.83 -0.8672 3615837 ACon1_001875 C[C@@H]1CCC2C(C)(C)[C@@H](CC[C@]2(C)[C@]31Cc4c(O3)c5CNC(=O)c5cc4O)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 N24 compound treatment 185360.0 15700.0 0.42 192480.0 21700.0 0.59 0.7134 0.9866 3615844 ACon1_001876 COC(=O)C12C(O)C34CC2N5C/C(=C/C)/C1CC5C4N(C)c6ccccc63 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O01 compound treatment 147920.0 -21700.0 -0.58 144160.0 -26600.0 -0.72 -0.9198 -0.9943 3615850 ACon1_001877 COc1cc2CCNC3Cc4ccccc4-c(c1OC)c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O02 compound treatment 172440.0 2820.0 0.08 164080.0 -6690.0 -0.18 -0.0747 -0.3809 3615852 ACon1_001878 C[C@@H]1O[C@@H](OC2C(O)C(O)C(CO)OC2O[C@@H]3[C@@H](O)[C@H](O)[C@H](O[C@H]3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7C8CC(C)(C)C(O)C(O)[C@]8(C)CC[C@]76C)C4(C)C)C(=O)O)[C@H](O)[C@H](O)[C@H]1OC9OCC(O)C(O)C9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O03 compound treatment 176960.0 7340.0 0.2 157440.0 -13300.0 -0.36 -0.1163 -0.2832 3552644 ACon1_001879 C[C@@H]1C[C@]2(O[C@H](O)[C@@]3(C)O[C@H]32)O[C@H]4C[C@@]5(C)[C@@H]6CC[C@@H]7[C@]8(C[C@@]68C[C@@H](OC(=O)C)[C@]5(C)[C@H]41)CC[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)C7(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O04 compound treatment 197040.0 27400.0 0.73 164280.0 -6490.0 -0.18 0.3944 0.523 3615859 ACon1_001880 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O05 compound treatment 82960.0 -86700.0 -2.32 37880.0 -133000.0 -3.6 -4.183 -0.9774 3558011 ACon1_001881 CC(=O)OC[C@]1(C)CC2[C@]3(CO[C@]42CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]3OC%10OCC(OC%11OC(CO)C(O)C(O)C%11O)C(O)C%10O)[C@@H](O)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O06 compound treatment 182400.0 12800.0 0.34 177800.0 7030.0 0.19 0.3763 0.9619 3615865 ACon1_001882 CC1C2CC3(CC(O)C4C(C)(CCCC4(C)C3(O)CC2)C(=O)OC5OC(CO)C(O)C(O)C5O)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O07 compound treatment 184680.0 15100.0 0.4 129440.0 -41300.0 -1.12 -0.5063 -0.4258 3554487 ACon1_001883 CN1C(Cc2ccccc2)C(=O)Nc3ccccc3C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O08 compound treatment 173400.0 3780.0 0.1 172360.0 1590.0 0.04 0.102 0.928 3615867 ACon1_001884 CC(=O)O[C@@H]1C[C@@]2(CO2)[C@](O)(CCc3ccoc3)[C@]4(CCC[C@@]5(C)C14)COC5=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O09 compound treatment 175440.0 5820.0 0.16 141320.0 -29400.0 -0.8 -0.4536 -0.5585 3615872 ACon1_001885 COC(=O)c1cccc(OC(C)C(=O)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O10 compound treatment 84200.0 -85400.0 -2.28 94680.0 -76100.0 -2.06 -3.0722 -0.9987 3615878 ACon1_001886 CC1C(C)c2cccnc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)C)[C@@H](O)[C@H](OC1=O)[C@]4(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O11 mock treatment 165600.0 -4020.0 -0.11 158160.0 -12600.0 -0.34 -0.3174 -0.887 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O12 mock treatment 168240.0 -1380.0 -0.04 145920.0 -24800.0 -0.67 -0.5018 -0.7448 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O13 compound treatment 14840.0 -155000.0 -4.14 12360.0 -158000.0 -4.29 -5.96 -0.9998 3615884 ACon1_001887 CCCCCc1cc(OC)c(CC=C(C)C)c(O)c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O14 compound treatment 185880.0 16300.0 0.43 173440.0 2670.0 0.07 0.3587 0.8136 3615887 ACon1_001888 CC(C)(O)C(O)Cc1cc(O)ccc1OC2OC(CO)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O15 compound treatment 154280.0 -15300.0 -0.41 150160.0 -20600.0 -0.56 -0.6846 -0.9886 3558264 ACon1_001889 O[C@@H]1C[C@](C[C@@H](O)[C@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)(OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O16 compound treatment 195160.0 25500.0 0.68 168560.0 -2210.0 -0.06 0.4408 0.6428 3615891 ACon1_001890 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)C1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O17 compound treatment 207600.0 38000.0 1.02 174000.0 3230.0 0.09 0.7802 0.7652 3615895 ACon1_001891 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O[C@@H]3OC[C@](O)(CO)[C@H]3O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O18 compound treatment 202680.0 33100.0 0.88 149120.0 -21600.0 -0.59 0.2109 0.1988 3615900 ACon1_001892 COC(=O)c1cc2cc(O)c(c(O)c2c(=O)o1)c3c(O)cc4cc(oc(=O)c4c3O)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O19 compound treatment 173600.0 3980.0 0.11 187600.0 16800.0 0.46 0.3975 0.8494 3615903 ACon1_001893 CC(=O)NC(CSC(CO)CCCCCCCCCC(=O)O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O20 compound treatment 164320.0 -5300.0 -0.14 169360.0 -1410.0 -0.04 -0.1272 -0.8662 3559173 ACon1_001894 COc1cc(OC)c(cc1OC)C(O)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O21 compound treatment 137920.0 -31700.0 -0.85 111480.0 -59300.0 -1.61 -1.7345 -0.9555 3615908 ACon1_001895 Cn/1c(=O)\c(=C\c2ccccc2)\n(C)c(=O)\c1=C\c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O22 compound treatment 169800.0 178.0 0.0 148880.0 -21900.0 -0.59 -0.4156 -0.7014 3559164 ACon1_001896 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@@H](OCCc3ccc(O)c(O)c3)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O23 compound treatment 205680.0 36100.0 0.96 163360.0 -7410.0 -0.2 0.5402 0.5484 3615916 ACon1_001897 CCC/C=C/C=C/C1CC(O)C(O)C(O)C1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 O24 compound treatment 157320.0 -12300.0 -0.33 133160.0 -37600.0 -1.02 -0.9526 -0.8903 3557540 ACon1_001898 COc1cc(O[C@@H]2O[C@H](CO[C@H]3OC[C@](O)(CO)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P01 compound treatment 152520.0 -17100.0 -0.46 162600.0 -8170.0 -0.22 -0.4798 -0.9443 3615923 ACon1_001899 C[C@H](CC/C=C(\C)/C(=O)OC1OC(CO)C(O)C(O)C1O)[C@H]2CC(O)[C@@]3(C)C4CC[C@@H]5[C@]6(C[C@@]46CC(O)[C@]23C)CC[C@H](O[C@@H]7OC(COC8OCC(O)C(O)C8O)C(O)C(O)C7O)C5(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P02 compound treatment 176640.0 7020.0 0.19 161360.0 -9410.0 -0.25 -0.0473 -0.1496 3615928 ACon1_001900 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]8O[C@H](CO)[C@H](O)[C@H](O)[C@H]8O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P03 compound treatment 148400.0 -21200.0 -0.57 138880.0 -31900.0 -0.86 -1.0118 -0.9793 3615934 ACon1_001901 CC1(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(=O)O)[C@](C)(CO)C5CC[C@@]4(C)C3(C)CC[C@@]2(C)[C@H](OC8OCC(O)C(OC9OC(CO)C(O)C(O)C9O)C8O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P04 compound treatment 10200.0 -159000.0 -4.26 7120.0 -164000.0 -4.43 -6.148 -0.9998 3615941 ACon1_001902 CCC(C)CCCCCCCCC1CC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P05 compound treatment 181480.0 11900.0 0.32 170800.0 34.1 0.0 0.2249 0.7092 3615944 ACon1_001903 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(OC%10OC(CO)C(O)C(O)C%10O)C(O)C9O)C(OC)C8O)C(C)O7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P06 compound treatment 11120.0 -159000.0 -4.24 8200.0 -163000.0 -4.4 -6.11 -0.9998 3553131 ACon1_001904 C[C@H]1CC[C@@H]2[C@H]([C@@H](C)C=C[C@H]2C1)C(=O)c3c(O)c(cn(O)c3=O)[C@]4(O)CC[C@@H](O)[C@H]5O[C@H]54 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P07 compound treatment 166480.0 -3140.0 -0.08 113320.0 -57400.0 -1.56 -1.1591 -0.7442 3615949 ACon1_001905 COC1OC(OC)C(O)(CC[C@@]2(O)[C@H](C)C[C@@H](O)C3[C@@](C)(CO)CCC[C@]32C)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P08 compound treatment 206080.0 36500.0 0.98 162360.0 -8410.0 -0.23 0.5287 0.5279 3557451 ACon1_001906 C[C@@]12C[C@H](O)C3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CC[C@@H]1C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P09 compound treatment 12720.0 -157000.0 -4.2 8840.0 -162000.0 -4.38 -6.0675 -0.9998 3615955 ACon1_001907 CC(=CCc1c(O)c(CC=C(C)C)c2OC(CC(=O)c2c1O)c3ccc(O)cc3O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P10 compound treatment 199360.0 29700.0 0.8 150240.0 -20500.0 -0.56 0.1695 0.1747 3559822 ACon1_001908 CC1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(C)CCC6(CCC54C)C(=O)OC7OC(CO)C(OC8OCC(OC9OC(CO)C(O)C(O)C9O)C(OC%10OCC(O)C(O)C%10O)C8O)C(O)C7O)C2(C)C)C(O)C(O)C1OC%11OCC(O)C(O)C%11O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P11 mock treatment 211200.0 41600.0 1.11 154040.0 -16700.0 -0.45 0.4662 0.3883 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P12 mock treatment 217360.0 47700.0 1.28 159800.0 -11000.0 -0.3 0.693 0.5286 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P13 compound treatment 160360.0 -9260.0 -0.25 136960.0 -33800.0 -0.92 -0.8223 -0.8673 3615961 ACon1_001909 COc1ccc(cc1O)C(C)C(=O)c2ccc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P14 compound treatment 138200.0 -31400.0 -0.84 132320.0 -38400.0 -1.04 -1.3303 -0.9944 3615963 ACon1_001910 OCC(=C)C(=O)O[C@H]1C[C@]23O[C@@H]3CC/C(=C/[C@H]4OC(=O)C(=C)[C@@H]41)/CO[C@@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P15 compound treatment 193320.0 23700.0 0.63 159400.0 -11400.0 -0.31 0.2307 0.3273 3559257 ACon1_001911 OC1(OCC2C(OCC21O)c3ccc4OCOc4c3)c5ccc6OCOc6c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P16 compound treatment 139480.0 -30100.0 -0.81 113840.0 -56900.0 -1.54 -1.6599 -0.9543 3615970 ACon1_001912 CC1(C)C(CCC2(C)C3CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C=C)C=C3CCC12)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P17 compound treatment 161640.0 -7980.0 -0.21 151360.0 -19400.0 -0.53 -0.5225 -0.9213 2116652 ACon1_001913 Oc1ccc(CCNC(=O)/C=C/c2ccc(O)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P18 compound treatment 169040.0 -582.0 -0.02 146800.0 -24000.0 -0.65 -0.4698 -0.7239 3615976 ACon1_001914 CC1OC(CC(O)C1O)c2cc3oc(cc(=O)c3c(O)c2O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P19 compound treatment 184840.0 15200.0 0.41 170920.0 154.0 0.0 0.2908 0.7143 3615980 ACon1_001915 CCC(C)C(OC1OC(C)C(O)C(O)C1O)C(C)C(=O)C(C)/C=C(\C)/CC(C)C(O)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P20 compound treatment 107240.0 -62400.0 -1.67 76640.0 -94100.0 -2.55 -2.9818 -0.9789 3615986 ACon1_001916 C[C@@H]1O[C@@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](C)O[C@H]2O[C@H]3[C@H](O)[C@@H](NC(=O)C)[C@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)CC[C@@]8(C(O)C[C@]76C)C(=O)OC9OCC(O)C(O)C9O)C4(C)C)O[C@@H]3COC%10OCC(O)C(OC%11OCC(O)C(O)C%11O)C%10O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P21 compound treatment 183120.0 13500.0 0.36 166640.0 -4130.0 -0.11 0.1763 0.4665 3615991 ACon1_001917 C/C=C/c1ccc(O)cc1C(=O)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P22 compound treatment 188160.0 18500.0 0.5 170840.0 74.1 0.0 0.3521 0.71 3615996 ACon1_001918 CC1=C2CC(CCC2(C)CCC1=O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P23 compound treatment 144160.0 -25500.0 -0.68 142400.0 -28400.0 -0.77 -1.0246 -0.9982 3559104 ACon1_001919 COC(=O)[C@H](O)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CC[C@@H](C3=C)[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2295 P24 compound treatment 176240.0 6620.0 0.18 192200.0 21400.0 0.58 0.5355 0.8827 3558533 ACon1_001920 OC[C@H]1O[C@@H](OC2OC=C3[C@@H](C[C@H]4N(CCc5c4[nH]c6ccccc56)C3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A01 compound treatment 239280.0 66500.0 1.78 238920.0 60100.0 1.63 2.4092 0.999 3616000 ACon1_001921 COC(=O)C12CC3CC(C(C)O)C2N(C3)CCc4c1[nH]c5cc(OC)ccc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A02 compound treatment 244160.0 71400.0 1.91 250640.0 71800.0 1.94 2.7259 1.0 3616002 ACon1_001922 C/C(=C\CC(C)(C)\C=C\Cc1ccoc1)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A03 compound treatment 263120.0 90400.0 2.42 284120.0 105000.0 2.85 3.7254 0.9966 3553562 ACon1_001923 CC(C)C1C(O)C2C(CCC(=O)C)C2(C)CC1OC(=O)/C=C/c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A04 compound treatment 227800.0 55100.0 1.47 256200.0 77400.0 2.1 2.5229 0.9851 3616008 ACon1_001924 C[C@@H]1CCOC(=O)/C=C/C=C\C(=O)O[C@@H]2C[C@H]3O[C@@H]4C=C(CO)CC[C@]4(COC(=O)[C@H]1O)[C@]2(C)[C@@]53CO5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A05 compound treatment 216200.0 43500.0 1.16 276480.0 97700.0 2.64 2.6917 0.9319 3554100 ACon1_001925 CCC(=O)OC1C(C)CC2(OC(=O)C)C1C(OC(=O)C)C3(CO3)CCC4C(/C=C(\C)/C2=O)C4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A06 compound treatment 226120.0 53400.0 1.43 259160.0 80400.0 2.18 2.5477 0.9791 3616012 ACon1_001926 COc1c(C2OCC(O)C(O)C2O)c(O)cc3oc(cc(=O)c13)c4ccc(OC5OC(C)C(O)C(O)C5O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A07 compound treatment 10520.0 -162000.0 -4.34 14920.0 -164000.0 -4.44 -6.2057 -0.9999 3616015 ACon1_001927 CCC/C=C/C(=O)O[C@H]1CC(C)(C)CC2[C@]34CCC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@@H]([C@@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@H](O)[C@H](O)[C@H]8O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O[C@@H]%10OC[C@](O)(CO)[C@H]%10O)[C@H]7O[C@@H]%11O[C@H](CO)[C@H](O)[C@H](O)[C@H]%11O)C(=O)O)C(C)(C)C6CC[C@@]5(C)[C@]4(C)C[C@@H](OC(=O)C)[C@]21[C@H](O)O3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A08 compound treatment 232760.0 60000.0 1.61 241840.0 63000.0 1.71 2.3418 0.9995 3616020 ACon1_001928 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@H]4O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c(oc3c2)c7ccc(O)cc7)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A09 compound treatment 191000.0 18300.0 0.49 225320.0 46500.0 1.26 1.2357 0.9149 3616025 ACon1_001929 CC1CC(=O)C2C34OC4(C(O)CC2(O)C1)C(O)c5c(O)cccc5C3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A10 compound treatment 186960.0 14200.0 0.38 221000.0 42200.0 1.14 1.0766 0.8942 3558789 ACon1_001930 OCC1OC(OC2C(O)C(O)C(CO)OC2OC3C(O)C(O)C(CO)OC3Oc4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)c(O)c6)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A11 compound treatment 220040.0 47300.0 1.27 224120.0 45300.0 1.23 1.762 0.9999 3616030 ACon1_001931 OCC1OC(C(O)C(O)C1OC2OCC(O)(CO)C2O)c3c(O)cc4OC(C(C(=O)c4c3O)c5c(oc6cc(O)cc(O)c6c5=O)c7ccc(O)cc7)c8ccc(O)cc8 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A12 compound treatment 238040.0 65300.0 1.75 260200.0 81400.0 2.2 2.7931 0.9934 3616033 ACon1_001932 OCC1OC(C(O)C(O)C1O)c2c(O)cc3occc(=O)c3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A13 mock treatment 208640.0 35900.0 0.96 234520.0 55700.0 1.51 1.7454 0.9762 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A14 mock treatment 218280.0 45500.0 1.22 244760.0 66000.0 1.79 2.1238 0.9826 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A15 compound treatment 242320.0 69600.0 1.86 221800.0 43000.0 1.16 2.139 0.9745 3616036 ACon1_001933 OC[C@H]1O[C@@H](Oc2ccc3c(=O)cc(oc3c2)c4ccc(O)cc4)[C@H](O[C@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A16 compound treatment 214320.0 41600.0 1.11 223440.0 44600.0 1.21 1.6408 0.9991 3616041 ACon1_001934 CCN1C[C@]2(C)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@](O)(C[C@@H]5OC)[C@]6(O)[C@@H](OC)C32)[C@H]16 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A17 compound treatment 8560.0 -164000.0 -4.39 10840.0 -168000.0 -4.55 -6.3209 -0.9998 3616047 ACon1_001935 C/C=C(/C)\C(=O)O[C@H]1CC(C)(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]6O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)C[C@@H](O)[C@@]12CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A18 compound treatment 30440.0 -142000.0 -3.81 37160.0 -142000.0 -3.83 -5.4032 -1.0 3552637 ACon1_001936 C[C@@H]1C[C@@H]2O[C@H]2/C=C\C=C\C(=O)Cc3c(Cl)c(O)cc(O)c3C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A19 compound treatment 36600.0 -136000.0 -3.64 17600.0 -161000.0 -4.36 -5.6611 -0.996 3616054 ACon1_001937 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4OC(=O)C)c2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A20 compound treatment 212920.0 40200.0 1.07 204240.0 25400.0 0.69 1.2467 0.9768 3559850 ACon1_001938 OC[C@H]1O[C@@H](OC(=O)/C=C/c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A21 compound treatment 110040.0 -62700.0 -1.68 135320.0 -43500.0 -1.18 -2.0185 -0.985 599 ACon1_001939 Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A22 compound treatment 222120.0 49400.0 1.32 229440.0 50600.0 1.37 1.9031 0.9998 3554279 ACon1_001940 CCCCCCC(C(=O)O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A23 compound treatment 230760.0 58000.0 1.55 229480.0 50700.0 1.37 2.0673 0.9981 3616064 ACon1_001941 COc1cc(oc(=O)c1C)/C(=C/C(C)(O)C(C)O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 A24 compound treatment 229240.0 56500.0 1.51 229680.0 50900.0 1.38 2.0424 0.9989 1099693 ACon1_001942 CC(C)(O)C(O)COc1c2occc2cc3ccc(=O)oc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B01 compound treatment 13680.0 -159000.0 -4.25 15520.0 -163000.0 -4.42 -6.1344 -0.9998 3498385 ACon1_001943 COC(=O)C1C(O)C=Cc2oc3cc(CO)cc(O)c3c(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B02 compound treatment 187240.0 14500.0 0.39 225840.0 47000.0 1.27 1.1745 0.8824 3554822 ACon1_001944 COc1cc(=O)oc(C(C)C(C)O)c1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B03 compound treatment 203960.0 31200.0 0.83 230960.0 52200.0 1.41 1.5888 0.9686 3616073 ACon1_001945 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@]1(C)O)C(=O)OC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B04 compound treatment 180880.0 8140.0 0.22 208960.0 30200.0 0.82 0.7311 0.8654 3559763 ACon1_001946 OC[C@H]1O[C@H](S/C(=N/OS(=O)(=O)O)/Cc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B05 compound treatment 206120.0 33400.0 0.89 217720.0 38900.0 1.05 1.3762 0.9966 3616080 ACon1_001947 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)C)[C@H](OC(=O)/C=C/c6ccccc6)[C@H]1OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B06 compound treatment 152640.0 -20100.0 -0.54 257040.0 78200.0 2.12 1.1173 0.5113 3553933 ACon1_001948 CC1=CC(=O)C2=C(C)CCC3[C@H](OC(=O)C3=C)[C@@]12O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B07 compound treatment 172600.0 -145.0 0.0 244000.0 65200.0 1.76 1.2452 0.7056 3616087 ACon1_001949 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(O)C(OC)C8O)C(C)O7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B08 compound treatment 173040.0 295.0 0.01 195560.0 16800.0 0.45 0.3263 0.7193 3553383 ACon1_001950 CC(=O)OC[C@H]1O[C@@H](Oc2ccccc2COC(=O)C3(O)C=CCCC3=O)[C@H](OC(=O)C)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B09 compound treatment 187280.0 14500.0 0.39 190400.0 11600.0 0.31 0.4968 0.9944 3554520 ACon1_001951 CO[C@H]1C(O[C@@H]2C[C@H]3O[C@@H]([C@@H](O)[C@H](O)[C@]3(O)O[C@H]12)C(=O)OC)n4cnc5c(N)ncnc45 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B10 compound treatment 167440.0 -5310.0 -0.14 200080.0 21300.0 0.58 0.3069 0.5174 1011613 ACon1_001952 Oc1cc(=O)oc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B11 compound treatment 12840.0 -160000.0 -4.28 16680.0 -162000.0 -4.39 -6.1281 -0.9999 2095401 ACon1_001953 CC(=CCCC1(C)Oc2c(C)cc3c4ccc(O)cc4[nH]c3c2C=C1)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B12 compound treatment 168400.0 -4350.0 -0.12 201760.0 23000.0 0.62 0.3572 0.565 3558299 ACon1_001954 OCCCc1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B13 mock treatment 165320.0 -7430.0 -0.2 182800.0 3990.0 0.11 -0.064 -0.2831 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B14 mock treatment 169360.0 -3390.0 -0.09 187480.0 8670.0 0.23 0.102 0.4053 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B15 compound treatment 184840.0 12100.0 0.32 221640.0 42800.0 1.16 1.0487 0.8711 1000142 ACon1_001955 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B16 compound treatment 169240.0 -3510.0 -0.09 189280.0 10500.0 0.28 0.1342 0.4493 3011353 ACon1_001956 Oc1ccccc1C(=O)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B17 compound treatment 174080.0 1340.0 0.04 191800.0 13000.0 0.35 0.274 0.7749 909 ACon1_001957 COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B18 compound treatment 180080.0 7340.0 0.2 180680.0 1870.0 0.05 0.1746 0.8615 1020611 ACon1_001958 Oc1cccc2oc(cc(=O)c12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B19 compound treatment 168040.0 -4710.0 -0.13 176240.0 -2570.0 -0.07 -0.1381 -0.9609 3557567 ACon1_001959 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](CO)C=C[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B20 compound treatment 232480.0 59700.0 1.6 211960.0 33200.0 0.9 1.7645 0.9628 3559544 ACon1_001960 C[C@H]1C[C@H](O)C[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B21 compound treatment 186560.0 13800.0 0.37 179080.0 272.0 0.01 0.2665 0.7211 3557523 ACon1_001961 C/C/1=C\CC[C@@]2(C)O[C@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B22 compound treatment 205360.0 32600.0 0.87 198640.0 19800.0 0.54 0.9965 0.9728 3177322 ACon1_001962 CC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B23 compound treatment 193880.0 21100.0 0.57 193280.0 14500.0 0.39 0.6768 0.984 3054971 ACon1_001963 O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 B24 compound treatment 161200.0 -11500.0 -0.31 185720.0 6910.0 0.19 -0.086 -0.2383 3557449 ACon1_001964 C[C@@]12CCC3[C@@H](CCC4=CC(=O)CC[C@]34C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C01 compound treatment 228920.0 56200.0 1.5 244520.0 65700.0 1.78 2.3204 0.9965 3616105 ACon1_001965 COc1ccc2OC3CCN(C3C(=O)NC(Cc4ccccc4)C(=O)N/C=C\c1c2)C(=O)C(NC(=O)C(C)N(C)C)C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C02 compound treatment 198520.0 25800.0 0.69 252360.0 73600.0 1.99 1.8955 0.8995 1034726 ACon1_001966 COc1ccc(cc1)c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C03 compound treatment 197440.0 24700.0 0.66 240600.0 61800.0 1.67 1.65 0.9174 3557683 ACon1_001967 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O[C@@H]8OC[C@](O)(CO)[C@H]8O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C04 compound treatment 178200.0 5460.0 0.15 215080.0 36300.0 0.98 0.7975 0.8034 3616115 ACon1_001968 COc1cc(ccc1O)c2oc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c(O)c3c(=O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C05 compound treatment 122880.0 -49900.0 -1.33 139520.0 -39300.0 -1.06 -1.6953 -0.9937 3555406 ACon1_001969 CON1c2ccccc2[C@@]3(C=C(O)C(=O)N4/C(=C/c5cnc[nH]5)/C(=O)N[C@]143)C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C06 compound treatment 186840.0 14100.0 0.38 205760.0 27000.0 0.73 0.7825 0.9528 3616121 ACon1_001970 CCCCCC(CC(O)CC(=O)OC(CCCCC)CC(CC(=O)O)OC1OC(CO)C(O)C(O)C1O)OC2OC(CO)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C07 compound treatment 11720.0 -161000.0 -4.31 16920.0 -162000.0 -4.38 -6.1447 -1.0 3616123 ACon1_001971 C/C=C(/C)\C(=O)O[C@H]1[C@H](OC(=O)/C=C/c2ccccc2)[C@@]3([C@H](O)O[C@@]45CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O[C@@H]%11OC[C@](O)(CO)[C@H]%11O)[C@H]8O[C@@H]%12O[C@H](CO)[C@H](O)[C@H](O)[C@H]%12O)C(=O)O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)C4CC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C08 compound treatment 11120.0 -162000.0 -4.32 15680.0 -163000.0 -4.42 -6.1798 -0.9999 3616129 ACon1_001972 CCCC(O)/C(=C/C1=C(C(=O)CC(CC(=O)O)OC(=O)N)C(=O)c2cccc(O)c2C1=O)/CC(C(=O)O)[N+](C)(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C09 compound treatment 164600.0 -8150.0 -0.22 189040.0 10200.0 0.28 0.0418 0.1187 3616135 ACon1_001973 O[C@H]1[C@@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3ccc(C(=O)CCc4ccc(O)cc4)c(O)c3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C10 compound treatment 156800.0 -15900.0 -0.43 174200.0 -4610.0 -0.12 -0.3898 -0.8772 1076495 ACon1_001974 CC1CCCCCC(=O)c2c(O)cc(O)cc2CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C11 mock treatment 161680.0 -11100.0 -0.3 177880.0 -928.0 -0.03 -0.227 -0.7644 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C12 mock treatment 165560.0 -7190.0 -0.19 190000.0 11200.0 0.3 0.0784 0.2184 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C13 compound treatment 168720.0 -4030.0 -0.11 185480.0 6670.0 0.18 0.0516 0.2454 3616143 ACon1_001975 C/C(=C/CCC(CO)C1CCC2(C)C3CCC4C5(CC35CCC12C)C(O)CC(OC6OC(CO)C(O)C(O)C6O)C4(C)C)/COC7OC(CO)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C14 compound treatment 160400.0 -12300.0 -0.33 186880.0 8070.0 0.22 -0.079 -0.1994 3616150 ACon1_001976 CCCCCCC(=O)OC1OC(CO)C(O)C2OCC(COC12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C15 mock treatment 187840.0 15100.0 0.4 171600.0 -7210.0 -0.2 0.1475 0.329 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C16 mock treatment 156080.0 -16700.0 -0.45 172240.0 -6570.0 -0.18 -0.4409 -0.9188 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C17 compound treatment 9240.0 -164000.0 -4.37 12280.0 -167000.0 -4.51 -6.2804 -0.9999 3616151 ACon1_001977 C/C=C(/C)\C(=O)O[C@H]1CC(C)(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]6O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)[C@@H](OC(=O)C)[C@@H](O)[C@@]12COC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C18 compound treatment 15600.0 -157000.0 -4.2 22440.0 -156000.0 -4.23 -5.9657 -1.0 3557642 ACon1_001978 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@H](O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC[C@@]78OC[C@]9(C8CC(C)(C)C[C@@H]9OC(=O)C)[C@H](O)C[C@]76C)C4(C)C)[C@@H]3O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C19 compound treatment 130920.0 -41800.0 -1.12 168400.0 -10400.0 -0.28 -0.9903 -0.8584 1147 ACon1_001979 COc1c2ccoc2cc3oc(=O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C20 compound treatment 210720.0 38000.0 1.02 229120.0 50300.0 1.36 1.6814 0.9896 3558157 ACon1_001980 COc1cc(O)c2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C21 compound treatment 12800.0 -160000.0 -4.28 13160.0 -166000.0 -4.48 -6.1963 -0.9997 3616160 ACon1_001981 CC1OC(OC2C(O)C(O)C(C)OC2OC3C(O)C(O)C(CO)OC3OC4C(O)C(OC(OC5CCC6(C)C(CCC7(C)C6CCC89OCC%10(CCC(C)(C)CC%109)C(O)CC87C)C5(C)C)C4OC%11OC(CO)C(O)C(O)C%11O)C(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C22 compound treatment 174520.0 1780.0 0.05 188840.0 10000.0 0.27 0.2256 0.8183 3558367 ACon1_001982 C[C@@H]1C[C@H]2OC[C@@]3(C)CCC[C@](C)(C23)[C@@]1(O)CCc4ccoc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C23 compound treatment 179200.0 6460.0 0.17 177040.0 -1770.0 -0.05 0.0882 0.4925 3616165 ACon1_001983 COc1ccc(/C=C/C(=O)O[C@@H]2[C@H](O)[C@@H](O)[C@H](C)O[C@H]2OC3C4O[C@]4(CO)[C@@H]5[C@H]3C=COC5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 C24 compound treatment 189520.0 16800.0 0.45 239160.0 60400.0 1.63 1.4726 0.8691 3557295 ACon1_001984 C/C=C/C1=CC(=O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D01 compound treatment 187600.0 14900.0 0.4 192400.0 13600.0 0.37 0.5412 0.9993 3616143 ACon1_001985 C/C(=C/CCC(CO)C1CCC2(C)C3CCC4C5(CC35CCC12C)C(O)CC(OC6OC(CO)C(O)C(O)C6O)C4(C)C)/COC7OC(CO)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D02 compound treatment 145720.0 -27000.0 -0.72 168600.0 -10200.0 -0.28 -0.7066 -0.913 3559089 ACon1_001986 OC1[C@H](OC(=O)c2cc(O)c(O)c(O)c2)OC3COC(=O)c4cc(O)c(O)c(O)c4-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]1[C@@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D03 compound treatment 193200.0 20500.0 0.55 200800.0 22000.0 0.6 0.8079 0.9991 3616174 ACon1_001987 OCC1OC(C(OC(=O)c2cc(O)c(O)c(O)c2)C(O)C1O)c3c(O)cc(O)c(C(=O)c4ccc(O)cc4)c3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D04 compound treatment 200040.0 27300.0 0.73 295080.0 116000.0 3.15 2.7421 0.8486 3559657 ACon1_001988 COc1cc(O)c(C(=O)CCc2ccc(OC)c(OC)c2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D05 compound treatment 244520.0 71800.0 1.92 204280.0 25500.0 0.69 1.8452 0.9045 3616180 ACon1_001989 CC1C2C(CC3C4CC(O[C@@H]5O[C@H](C)[C@@H](O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)[C@H](O)[C@H]5O)C7CC(O)CCC7(C)C4CCC23C)OC81OCC(C)CC8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D06 compound treatment 168520.0 -4230.0 -0.11 234960.0 56200.0 1.52 0.995 0.6527 3559746 ACon1_001990 COc1cc2N3[C@H]4[C@H]5[C@H]6C[C@@H]7N(CC[C@@]74c2cc1OC)CC6=CCO[C@H]5CC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D07 compound treatment 159640.0 -13100.0 -0.35 204920.0 26100.0 0.71 0.252 0.3194 3553158 ACon1_001991 C[C@H]1OC(=O)[C@@]23C(=C)[C@]4(C)OC(=O)[C@@]31O[C@]5([C@@H]4O)C(=C)[C@@]6(CC[C@]25C)C=CC(=O)OC6(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D08 compound treatment 125000.0 -47700.0 -1.28 133640.0 -45200.0 -1.22 -1.7677 -0.9998 3559359 ACon1_001992 O[C@@H]1CO[C@@H](O[C@@H](CCc2ccc(O)c(O)c2)CC(=O)CCc3ccc(O)c(O)c3)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D09 compound treatment 12440.0 -160000.0 -4.29 18120.0 -161000.0 -4.35 -6.1081 -1.0 3616190 ACon1_001993 C/C=C/[C@H]1[C@@H](C=C(C)[C@H]2CC[C@H](C)C[C@H]12)C(=O)c3c(O)c(c[nH]c3=O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D10 compound treatment 163320.0 -9430.0 -0.25 203760.0 25000.0 0.68 0.2994 0.4152 3554007 ACon1_001994 CC1CC2C=CC3COC(=O)C3(C)C2CC1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D11 mock treatment 163680.0 -9070.0 -0.24 197320.0 18500.0 0.5 0.1829 0.3286 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D12 mock treatment 175920.0 3180.0 0.08 193880.0 15100.0 0.41 0.3486 0.8364 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D13 compound treatment 161680.0 -11100.0 -0.3 205920.0 27100.0 0.73 0.3097 0.3914 3559637 ACon1_001995 COC(=O)C12CCC(C)C(C)C2C3=CCC4C5(C)CCC(OC(=O)C)C(C)(C)C5CCC4(C)C3(C)CC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D14 compound treatment 178560.0 5820.0 0.16 248280.0 69500.0 1.88 1.4399 0.763 3079231 ACon1_001996 CC1(C)O[C@H]2CC(=O)OC[C@@]23[C@H]1CC(=O)[C@]4(C)[C@@H]3CC[C@@]5(C)[C@@H](OC(=O)[C@H]6O[C@]654)c7ccoc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D15 mock treatment 161320.0 -11400.0 -0.31 180480.0 1670.0 0.05 -0.1841 -0.5959 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D16 mock treatment 162480.0 -10300.0 -0.27 194920.0 16100.0 0.44 0.1143 0.2217 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D17 compound treatment 11840.0 -161000.0 -4.3 35760.0 -143000.0 -3.87 -5.7818 -0.9986 2838 ACon1_001997 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D18 compound treatment 181880.0 9140.0 0.24 200040.0 21200.0 0.57 0.5792 0.9274 3559519 ACon1_001998 C[C@@H]1CC[C@]2(C)[C@H](CCC=C2C(=O)O)[C@@]1(C)CCc3ccoc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D19 compound treatment 10960.0 -162000.0 -4.33 14080.0 -165000.0 -4.46 -6.2135 -0.9999 1054601 ACon1_001999 Cc1cc2c3ccccc3[nH]c2c4C=CC(C)(C)Oc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D20 compound treatment 90320.0 -82400.0 -2.2 88080.0 -90700.0 -2.46 -3.2958 -0.9985 3559588 ACon1_002000 OC/C/1=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](O)C/C(=C\CC1)/C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D21 compound treatment 184680.0 11900.0 0.32 181640.0 2830.0 0.08 0.28 0.8527 3559469 ACon1_002001 CC1(C)CC2C1[C@@H](O)C/C(=C/CCC2=C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D22 compound treatment 171720.0 -1030.0 -0.03 189520.0 10700.0 0.29 0.1857 0.6374 3557446 ACon1_002002 C[C@@]12C[C@H](O)C3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D23 compound treatment 209600.0 36900.0 0.99 187600.0 8790.0 0.24 0.8654 0.8533 3559627 ACon1_002003 CCCCCCCCC#CCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 D24 compound treatment 174880.0 2140.0 0.06 178960.0 152.0 0.0 0.0433 0.7561 3557443 ACon1_002004 C[C@@]12C[C@H](O)C3[C@@H](CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E01 mock treatment 169880.0 -2870.0 -0.08 184760.0 5950.0 0.16 0.0598 0.3349 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E02 mock treatment 185080.0 12300.0 0.33 227080.0 48300.0 1.31 1.1574 0.8587 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E03 compound treatment 180200.0 7460.0 0.2 177840.0 -968.0 -0.03 0.1225 0.609 3557620 ACon1_002005 COC(=O)C(=C)[C@]1(O[C@]2(C)CC1=O)[C@H](C[C@@]3(C)OC(=O)/C(=C/C)/[C@]3(O)CC2)OC(=O)C(=C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E04 compound treatment 162800.0 -9950.0 -0.27 186160.0 7350.0 0.2 -0.0474 -0.1425 3616208 ACon1_002006 OCC1OC(OC2OC=C(C(CC(=O)O)C2C=C)C(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E05 compound treatment 155400.0 -17300.0 -0.46 189600.0 10800.0 0.29 -0.1215 -0.2215 3616212 ACon1_002007 OC1C(O)C(COC(=O)/C=C/c2ccc(O)cc2)OC(OC(=O)/C=C/c3ccc(O)c(O)c3)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E06 compound treatment 173240.0 495.0 0.01 209640.0 30800.0 0.83 0.5996 0.7182 3558000 ACon1_002008 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)/C=C/c7ccccc7)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E07 compound treatment 153240.0 -19500.0 -0.52 385360.0 207000.0 5.59 3.5851 0.6384 3555029 ACon1_002009 COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1OC5OC(COC(=O)CC(C)(O)CC(=O)O)C(O)C(O)C5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E08 compound treatment 169200.0 -3550.0 -0.09 285360.0 107000.0 2.88 1.9727 0.6835 3616218 ACon1_002010 CC1OC(Oc2cc(O)c3c(=O)c(OC4OCC(O)C(O)C4O)c(oc3c2)c5ccc(O)cc5)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E09 mock treatment 152600.0 -20100.0 -0.54 182920.0 4110.0 0.11 -0.3023 -0.5494 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E10 mock treatment 148160.0 -24600.0 -0.66 180520.0 1710.0 0.05 -0.4322 -0.6556 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E11 compound treatment 168520.0 -4230.0 -0.11 185680.0 6870.0 0.19 0.0516 0.2372 3616221 ACon1_002011 COc1cc(/C=C/C(=O)OC[C@H]2O[C@@H](O[C@@H]3OC=C[C@H]4[C@H](O)[C@@H]5O[C@]5(CO)[C@H]43)[C@H](O)[C@@H](O)[C@@H]2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E12 compound treatment 193880.0 21100.0 0.57 183880.0 5070.0 0.14 0.4968 0.854 3616227 ACon1_002012 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](C)[C@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E13 compound treatment 15680.0 -157000.0 -4.2 18520.0 -160000.0 -4.34 -6.0392 -0.9999 3616231 ACon1_002013 C/C(=C/CC[C@@H](CO)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@H]4[C@]5(C[C@@]35CC[C@]12C)[C@@H](O)C[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C4(C)C)/CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E14 compound treatment 192560.0 19800.0 0.53 190640.0 11800.0 0.32 0.6013 0.9709 3614428 ACon1_002014 COC(=O)c1c(C)cc2CC3(Oc2c(C)c1=O)C(C)CCC(C(C)(C)O)C3(C)CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E15 compound treatment 150640.0 -22100.0 -0.59 182320.0 3510.0 0.1 -0.3509 -0.5859 3616237 ACon1_002015 CC(=O)O[C@@H]1[C@@H](O)[C@H](OC(=O)c2ccccc2)[C@@H](CO)O[C@H]1Oc3cc(O)cc(O)c3C(=O)c4cccc(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E16 compound treatment 93280.0 -79500.0 -2.13 138400.0 -40400.0 -1.09 -2.2766 -0.9523 3616246 ACon1_002016 CC1C2C(CC3C4CC=C5CC(CCC5(C)C4CCC23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)OC91CCC(C)CN9 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E17 mock treatment 146520.0 -26200.0 -0.7 164120.0 -14700.0 -0.4 -0.7772 -0.9638 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E18 mock treatment 144200.0 -28500.0 -0.76 179480.0 672.0 0.02 -0.527 -0.6901 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E19 compound treatment 152680.0 -20100.0 -0.54 161040.0 -17800.0 -0.48 -0.7196 -0.9985 3616250 ACon1_002017 COc1cc(cc(O)c1OC)c2cc(O)c(OC)c(OC)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E20 compound treatment 12200.0 -161000.0 -4.29 13760.0 -165000.0 -4.47 -6.1961 -0.9998 3554291 ACon1_002018 CCCCCCCC(=O)OC1C(OC(=O)/C(=C/C)/C)C(=C2C3OC(=O)C(C)(O)C3(O)C(CC(C)(OC(=O)C)C12)OC(=O)CCC)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E21 compound treatment 140760.0 -32000.0 -0.86 160920.0 -17900.0 -0.48 -0.9474 -0.9637 3616255 ACon1_002019 CC[C@H]1C(=O)CC2C3CCC4C[C@@H](O)[C@]5(O)C[C@]4(CO5)C3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E22 compound treatment 163120.0 -9630.0 -0.26 188760.0 9950.0 0.27 0.0085 0.0227 3558178 ACon1_002020 CC1(O)CCCC2(C)CCC(CC12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E23 compound treatment 163120.0 -9630.0 -0.26 166320.0 -12500.0 -0.34 -0.4211 -0.991 3558962 ACon1_002021 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H](C)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 E24 compound treatment 69480.0 -103000.0 -2.76 105960.0 -72800.0 -1.97 -3.3477 -0.9864 3616265 ACon1_002022 CC(C)c1cc(O)c(C)c(c1O)c2c(C)c(O)cc(C(C)C)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F01 mock treatment 185920.0 13200.0 0.35 209120.0 30300.0 0.82 0.8295 0.9288 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F02 mock treatment 172960.0 215.0 0.01 210920.0 32100.0 0.87 0.6188 0.7118 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F03 compound treatment 190720.0 18000.0 0.48 202880.0 24100.0 0.65 0.8008 0.9888 3616267 ACon1_002023 C[C@H]1O[C@@H](OC2CC3C(=CC2(C)C=C)CCC4C(C)(C)C(CCC34C)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F04 compound treatment 92280.0 -80500.0 -2.15 131440.0 -47400.0 -1.28 -2.4287 -0.9694 3559767 ACon1_002024 COc1ccc(/C=C/C(=O)c2c(OC)cc(OC)c(CC=C(C)C)c2OC)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F05 compound treatment 200840.0 28100.0 0.75 191400.0 12600.0 0.34 0.7724 0.9361 3616273 ACon1_002025 C[C@H]1O[C@@H](OC(C)(CC/C=C(\C)/C(=O)O)C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F06 compound treatment 158680.0 -14100.0 -0.38 216920.0 38100.0 1.03 0.4636 0.4221 1020610 ACon1_002026 Oc1ccc2oc(cc(=O)c2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F07 compound treatment 171200.0 -1550.0 -0.04 198880.0 20100.0 0.54 0.355 0.6514 3616280 ACon1_002027 CC(=CCCC(C)(O)C1Cc2cc(cc(CC=C(C)C)c2O1)C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F08 compound treatment 147360.0 -25400.0 -0.68 193160.0 14400.0 0.39 -0.2054 -0.2625 3616283 ACon1_002028 CCCCOC(=O)C(N)CCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F09 mock treatment 151360.0 -21400.0 -0.57 169760.0 -9050.0 -0.24 -0.5777 -0.9284 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F10 mock treatment 164280.0 -8470.0 -0.23 166560.0 -12200.0 -0.33 -0.3946 -0.9827 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F11 compound treatment 167360.0 -5390.0 -0.14 152720.0 -26100.0 -0.71 -0.6013 -0.8341 3559302 ACon1_002029 CC(C1CCC2C3CC=C4CC(CC(O)C4(C)C3CCC12C)OC5OC(COC6OC(CO)C(O)C(O)C6O)C(O)C(O)C5O)C7CC(=C(C)C(=O)O7)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F12 compound treatment 143120.0 -29600.0 -0.79 213440.0 34600.0 0.94 0.1026 0.0836 3553842 ACon1_002030 CC1(C)[C@@H]2CC[C@]3(C2)[C@H](CC[C@@H]3C1=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F13 compound treatment 141320.0 -31400.0 -0.84 164320.0 -14500.0 -0.39 -0.8717 -0.9398 3559459 ACon1_002031 CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F14 compound treatment 158800.0 -13900.0 -0.37 170840.0 -7970.0 -0.22 -0.4163 -0.9661 3558542 ACon1_002032 COc1cc(/C=C/CO)ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F15 compound treatment 13720.0 -159000.0 -4.25 16600.0 -162000.0 -4.39 -6.113 -0.9999 3553373 ACon1_002033 CC(=O)OC[C@@]12CCC(=C[C@H]2O[C@@H]3[C@H](O)[C@@H](OC(=O)C)[C@@]1(C)[C@@]43CO4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F16 compound treatment 166120.0 -6630.0 -0.18 149960.0 -28800.0 -0.78 -0.6775 -0.846 3559439 ACon1_002034 C/C=C(/C)\C(=O)OC1Cc2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F17 mock treatment 168680.0 -4070.0 -0.11 175840.0 -2970.0 -0.08 -0.1337 -0.9889 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F18 mock treatment 145440.0 -27300.0 -0.73 159120.0 -19700.0 -0.53 -0.8933 -0.988 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F19 compound treatment 152480.0 -20300.0 -0.54 156160.0 -22600.0 -0.61 -0.8168 -0.9981 3559364 ACon1_002035 COc1cc2[nH]c3ccccc3c2cc1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F20 compound treatment 140720.0 -32000.0 -0.86 165480.0 -13300.0 -0.36 -0.8609 -0.9261 1308020 ACon1_002036 COc1ccc(cc1)c2cc(=O)c3ccccc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F21 compound treatment 154760.0 -18000.0 -0.48 185360.0 6550.0 0.18 -0.2147 -0.4188 1112402 ACon1_002037 COc1ccc2ccc(=O)oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F22 compound treatment 141240.0 -31500.0 -0.84 189280.0 10500.0 0.28 -0.3954 -0.4447 3557454 ACon1_002038 C[C@@]12CCC3[C@@H](CC[C@H]4CC(=O)CC[C@@]43C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F23 compound treatment 186080.0 13300.0 0.36 162840.0 -16000.0 -0.43 -0.0535 -0.0954 3559628 ACon1_002039 CCCCCCCCC#CCCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 F24 compound treatment 167000.0 -5750.0 -0.15 201640.0 22800.0 0.62 0.3284 0.5156 3557444 ACon1_002040 C[C@@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G01 compound treatment 175520.0 2780.0 0.07 179160.0 352.0 0.01 0.0592 0.7914 3616293 ACon1_002041 CCC1CN2CCC3(C2CC1/C(=C/OC)/C(=O)OC)C(=O)Nc4cccc(O)c43 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G02 compound treatment 159040.0 -13700.0 -0.37 191640.0 12800.0 0.35 -0.0136 -0.0269 3558908 ACon1_002042 CC1(C)CCC[C@@]2(C)C1CC(=O)c3cc(O)c(O)cc32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G03 mock treatment 194880.0 22100.0 0.59 186520.0 7710.0 0.21 0.5663 0.902 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G04 mock treatment 169080.0 -3670.0 -0.1 175240.0 -3570.0 -0.1 -0.1376 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G05 compound treatment 195880.0 23100.0 0.62 205160.0 26400.0 0.71 0.942 0.9975 3557720 ACon1_002043 COc1cc(O)c2c(=O)c(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H]4O)[C@H](O)[C@H](O)[C@H]3O)c(oc2c1)c6ccc(O)c(O)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G06 compound treatment 188320.0 15600.0 0.42 221000.0 42200.0 1.14 1.1023 0.9066 3616299 ACon1_002044 COC(=O)Cc1c(oc2cc(C)cc(O)c2c1=O)C(=CC(=O)O)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G07 compound treatment 185600.0 12900.0 0.34 186840.0 8030.0 0.22 0.3969 0.9756 3616301 ACon1_002045 O[C@H]1[C@@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3ccc(C(=O)/C=C/c4ccccc4)c(O)c3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G08 compound treatment 147800.0 -24900.0 -0.67 167880.0 -10900.0 -0.3 -0.681 -0.933 3616305 ACon1_002046 CC(C)(O)/C=C/C(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G09 compound treatment 156840.0 -15900.0 -0.43 172800.0 -6010.0 -0.16 -0.4158 -0.913 3553481 ACon1_002047 CC(C)(O)CCCC(C)(O)c1ccc(cc1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G10 compound treatment 164240.0 -8510.0 -0.23 191680.0 12900.0 0.35 0.0855 0.2056 3616309 ACon1_002048 CC1OC(OC2C(O)C(O)C(OC(=O)[C@@]34CCC(C)(C)CC4C5=CCC6[C@@]7(C)CC[C@H](OC8OC(C)C(OC9OCC(O)(COC%10OCC(O)C(OC%11OCC(OC%12OCC(O)(CO)C%12O)C(O)C%11O)C%10O)C9O)C(O)C8O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)CC3)OC2CO)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G11 compound treatment 141160.0 -31600.0 -0.84 180440.0 1630.0 0.04 -0.5662 -0.6692 3558718 ACon1_002049 COc1cc(/C=C/c2cc(O)cc(O)c2)ccc1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G12 compound treatment 173080.0 335.0 0.01 169520.0 -9290.0 -0.25 -0.1715 -0.6815 3616313 ACon1_002050 CC1OC(OC2C(O)C(O)C(COC3OCC(O)C(O)C3O)OC2OC(=O)C45CCC(C)(C)CC5C6=CCC7C8(C)CCC(OC9OC(CO)C(OC%10OC(C(OC%11OCC(O)C(O)C%11O)C(O)C%10O)C(=O)O)C(O)C9O)C(C)(CO)C8CCC7(C)C6(C)CC4)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G13 compound treatment 156240.0 -16500.0 -0.44 164280.0 -14500.0 -0.39 -0.5903 -0.9983 3616315 ACon1_002051 C[C@@H]1C[C@@H](OC(=O)C)C2[C@]3(C)CCC[C@]2(COC3=O)[C@@]1(O)CCc4ccoc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G14 compound treatment 156360.0 -16400.0 -0.44 160400.0 -18400.0 -0.5 -0.6623 -0.9979 3616319 ACon1_002052 C/C=C\C(=C\[C@H](C)C(=O)C[C@H](O)CC1CC(=O)NC(=O)C1)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G15 compound treatment 156320.0 -16400.0 -0.44 162440.0 -16400.0 -0.44 -0.624 -1.0 3616320 ACon1_002053 C[C@@H]([C@H]1CC[C@](C)(O1)C=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G16 compound treatment 151040.0 -21700.0 -0.58 162520.0 -16300.0 -0.44 -0.7223 -0.9908 3616324 ACon1_002054 CC1C2C(CC3C4CC=C5CC(CCC5(C)C4CCC23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O)OC81CCC(C)CN8 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G17 compound treatment 158560.0 -14200.0 -0.38 172720.0 -6090.0 -0.16 -0.3848 -0.9303 3616327 ACon1_002055 COc1cc(CC(CO)C(CO)Cc2cc(OC)c(O)c(c2)c3cc(CC(CO)C(CO)Cc4ccc(O)c(OC)c4)cc(OC)c3O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G18 compound treatment 14000.0 -159000.0 -4.25 15600.0 -163000.0 -4.42 -6.1269 -0.9998 3553093 ACon1_002056 C[C@H]1[C@H]2[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@]25[C@@H](/C=C/C[C@H](C)\C=C(/C)\[C@@H](O)C(=O)\C=C\C5=O)[C@@H]6O[C@@]61C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G19 mock treatment 155240.0 -17500.0 -0.47 168280.0 -10500.0 -0.29 -0.5326 -0.9717 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G20 mock treatment 164040.0 -8710.0 -0.23 165520.0 -13300.0 -0.36 -0.419 -0.9778 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G21 compound treatment 181280.0 8540.0 0.23 183400.0 4590.0 0.12 0.2493 0.9592 3616329 ACon1_002057 CC1=CC[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G22 compound treatment 155440.0 -17300.0 -0.46 182880.0 4070.0 0.11 -0.2494 -0.524 3616332 ACon1_002058 OC1COC(OCC2OC(O[C@H](C#N)c3ccccc3)C(O)C(O)C2O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G23 compound treatment 160960.0 -11800.0 -0.32 173600.0 -5210.0 -0.14 -0.3226 -0.9342 3616337 ACon1_002059 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OCC(O)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 G24 compound treatment 137000.0 -35700.0 -0.96 130520.0 -48300.0 -1.31 -1.6005 -0.9882 3616341 ACon1_002060 COc1c(O)c(C(=O)/C=C\c2ccccc2)c(OC)c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H01 compound treatment 198520.0 25800.0 0.69 225880.0 47100.0 1.27 1.3886 0.9584 3616345 ACon1_002061 CC1CCC2(C)C(CC(O)C(O)C32CO3)C1(C)CCC4=CC(O)OC4=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H02 compound treatment 171640.0 -1110.0 -0.03 173880.0 -4930.0 -0.13 -0.1152 -0.8433 3559239 ACon1_002062 O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](O)[C@H]1OC(=O)c4cc(O)c(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H03 mock treatment 184400.0 11700.0 0.31 268640.0 89800.0 2.43 1.9401 0.7913 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H04 mock treatment 174000.0 1260.0 0.03 280440.0 102000.0 2.75 1.9693 0.7157 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H05 compound treatment 216120.0 43400.0 1.16 255120.0 76300.0 2.07 2.2813 0.9628 3616347 ACon1_002063 CC(CC/C=C(\C)/C(=O)O)C1CC(O)C2(C)C3CCC4C5(CC35CC(O)C12C)CCC(OC6OCC(O)C(O)C6O)C4(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H06 compound treatment 183640.0 10900.0 0.29 231880.0 53100.0 1.44 1.222 0.8336 450 ACon1_002064 COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H07 compound treatment 170960.0 -1790.0 -0.05 142080.0 -36700.0 -0.99 -0.7368 -0.7402 3616351 ACon1_002065 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OC(=O)[C@@]34CCC(C)(C)CC4C5=CCC6[C@@]7(C)CC[C@H](OC8OC(CO)C(OC9OCC(O)C(O)C9O)C(O)C8O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)CC3O)O[C@H]2CO)[C@H](O)[C@H](O)[C@H]1O[C@H]%10OC[C@](O)(CO)[C@H]%10O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H08 compound treatment 15640.0 -157000.0 -4.2 17080.0 -162000.0 -4.38 -6.0675 -0.9998 3551814 ACon1_002066 CC(=CCc1c(O)c(CC=C(C)C)c2OC(CC(=O)c2c1O)c3ccc(O)cc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H09 compound treatment 163320.0 -9430.0 -0.25 174720.0 -4090.0 -0.11 -0.2565 -0.9317 3553447 ACon1_002067 CC(C)(C1CC[C@@]2(C)O[C@](C)(CCC2[C@@]1(C)CC(=O)O)C=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H10 compound treatment 174600.0 1860.0 0.05 215760.0 37000.0 1.0 0.7425 0.7413 3557584 ACon1_002068 C/C(=C\CO)/CC[C@H]1C(=C)CCC2[C@@](C)(CCC[C@]12C)C=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H11 compound treatment 187120.0 14400.0 0.38 195200.0 16400.0 0.44 0.5857 0.9975 2321 ACon1_002069 COc1ccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc2c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H12 compound treatment 170800.0 -1950.0 -0.05 226120.0 47300.0 1.28 0.8689 0.6778 3553497 ACon1_002070 CC(C)[C@]1(O)CC[C@]2(C)CC=C(C)C[C@H](O)[C@@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H13 compound treatment 13320.0 -159000.0 -4.26 15000.0 -164000.0 -4.43 -6.1512 -0.9998 3187885 ACon1_002071 CC[C@H]([C@H]1O[C@@](CC)(C[C@@H]1C)[C@H]2CC[C@](O)(CC)[C@H](C)O2)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H14 compound treatment 183560.0 10800.0 0.29 202560.0 23800.0 0.64 0.6592 0.935 3559539 ACon1_002072 C[C@H]1CCC2OC32CC4(O)OC(=O)C(=C4[C@@H](OC(=O)C(=C)C)[C@]13C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H15 compound treatment 174880.0 2140.0 0.06 187880.0 9070.0 0.25 0.2141 0.8489 3616359 ACon1_002073 CC(CNC(=O)CC[C@]1(C)[C@@H](CC(=O)N)[C@H]2N=C1/C(=C/3\N=C(/C=C/4\N=C(/C(=C\5/[C@@H](CCC(=O)N)[C@](C)(CC(=O)N)[C@@]2(C)N5[Co+]C#N)/C)\[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)\C(C)(C)[C@@H]3CCC(=O)N)/C)OP(=O)(O)O[C@@H]6[C@H](O)[C@@H](O[C@H]6CO)n7cnc8cc(C)c(C)cc78 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H16 compound treatment 199200.0 26500.0 0.71 194640.0 15800.0 0.43 0.8035 0.9711 3559651 ACon1_002074 COc1ccc2C(=O)/C(=C(\O)/c3ccccc3)/Oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H17 compound treatment 172400.0 -345.0 -0.01 163360.0 -15400.0 -0.42 -0.3022 -0.7225 3557456 ACon1_002075 C[C@H](CCC(=O)O)[C@H]1CCC2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3C=C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H18 compound treatment 207480.0 34700.0 0.93 155240.0 -23600.0 -0.64 0.2058 0.1826 3559549 ACon1_002076 C/C=C(/CO)\C(=O)O[C@@H]1CC[C@H]2C(=O)c3occ(C)c3C[C@]2(C)[C@H]1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H19 mock treatment 170320.0 -2430.0 -0.06 181760.0 2950.0 0.08 0.0106 0.1034 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H20 mock treatment 179640.0 6900.0 0.18 161840.0 -17000.0 -0.46 -0.1944 -0.3927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H21 compound treatment 174800.0 2060.0 0.05 171040.0 -7770.0 -0.21 -0.1098 -0.5053 3559433 ACon1_002077 CC#CCc1cc2ccccc2c(=O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H22 compound treatment 182560.0 9820.0 0.26 174600.0 -4210.0 -0.11 0.1051 0.3672 3557447 ACon1_002078 CC(=O)[C@H]1CCC2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H23 compound treatment 184760.0 12000.0 0.32 179360.0 552.0 0.01 0.2378 0.7392 3063892 ACon1_002079 COc1cc2ccc(=O)oc2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 H24 compound treatment 19520.0 -153000.0 -4.1 21520.0 -157000.0 -4.26 -5.9091 -0.9998 3559653 ACon1_002080 O/C(=C\C(=O)/C=C/c1ccc(O)cc1)/C=C/c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I01 compound treatment 165800.0 -6950.0 -0.19 173080.0 -5730.0 -0.16 -0.241 -0.996 3616365 ACon1_002081 C[C@]1(CN2C3C4C(O)[C@H]5C(O)C6[C@]73CC(=O)C1)C7[C@@H]2C[C@@]46CC5=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I02 compound treatment 69960.0 -103000.0 -2.75 73920.0 -105000.0 -2.84 -3.952 -0.9999 3616368 ACon1_002082 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(O)C6O)C(=O)O)C(CO)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I03 compound treatment 152120.0 -20600.0 -0.55 180920.0 2110.0 0.06 -0.3497 -0.6304 3558097 ACon1_002083 COc1cc(C[C@@H]2[C@@H](Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)COC2=O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I04 compound treatment 114000.0 -58700.0 -1.57 113080.0 -65700.0 -1.78 -2.3694 -0.9981 3559868 ACon1_002084 OC1C2NCCc3cc4OCOc4c(-c5ccccc15)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I05 mock treatment 159520.0 -13200.0 -0.35 180720.0 1910.0 0.05 -0.2135 -0.5973 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I06 mock treatment 163520.0 -9230.0 -0.25 169320.0 -9490.0 -0.26 -0.3561 -0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I07 compound treatment 15560.0 -157000.0 -4.2 15000.0 -164000.0 -4.43 -6.1088 -0.9996 3616375 ACon1_002085 CC(=CCC[C@@](C)(O)[C@H]1CC[C@]2(C)C1CC(O)C3[C@@]2(C)CCC4C(C)(C)[C@@H](O)C[C@@H](O)[C@@]43C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I08 compound treatment 153640.0 -19100.0 -0.51 180120.0 1310.0 0.04 -0.3362 -0.6564 3616379 ACon1_002086 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=C(Cl)C(=O)C(C)(O)C(O)C2CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I09 compound treatment 176600.0 3860.0 0.1 207280.0 28500.0 0.77 0.618 0.7946 3558841 ACon1_002087 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I10 compound treatment 38800.0 -134000.0 -3.58 45120.0 -134000.0 -3.62 -5.0927 -1.0 3616383 ACon1_002088 CCCCCC(=O)Cc1cc(O)c(O)c2Oc3c(CCCCC)c(C(=O)O)c(O)cc3OC(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I11 compound treatment 148960.0 -23800.0 -0.64 195760.0 17000.0 0.46 -0.1254 -0.1598 3616384 ACon1_002089 OCC12OC2C(O)C3C=COC(OC4OC(COC(=O)/C=C/c5ccccc5)C(O)C(O)C4O)C31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I12 compound treatment 23080.0 -150000.0 -4.0 24280.0 -155000.0 -4.18 -5.789 -0.9998 3616386 ACon1_002090 CO[C@H]1[C@H](O)[C@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)[C@@H](CC[C@]45O)C6=CC(=O)OC6)C2)O[C@@H](C)[C@@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I13 compound treatment 36400.0 -136000.0 -3.65 32920.0 -146000.0 -3.95 -5.3716 -0.9992 3616388 ACon1_002091 CC(=C)C(=O)O[C@H]1C[C@@]2(C)O[C@@H]2[C@H]3O[C@H]3C(=C)[C@@H](O)[C@H]4OC(=O)C(=C)[C@@H]41 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I14 compound treatment 152000.0 -20700.0 -0.55 167400.0 -11400.0 -0.31 -0.6108 -0.9617 3558106 ACon1_002092 OC[C@H]1O[C@@H](Oc2ccc3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I15 compound treatment 172160.0 -585.0 -0.02 190080.0 11300.0 0.31 0.2047 0.67 3616390 ACon1_002093 CC(=O)O[C@@H]1[C@@H](O)[C@H](OC(=O)c2ccccc2)[C@@H](CO)O[C@H]1Oc3cc(O)cc(O)c3C(=O)c4cc(O)cc(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I16 compound treatment 145560.0 -27200.0 -0.73 128960.0 -49800.0 -1.35 -1.4684 -0.9579 959 ACon1_002094 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I17 compound treatment 178640.0 5900.0 0.16 185840.0 7030.0 0.19 0.2461 0.9956 3557761 ACon1_002095 OCC1OC(OCC2OC(NCCc3ccc(O)cc3)C(O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I18 compound treatment 184240.0 11500.0 0.31 179640.0 832.0 0.02 0.2333 0.7569 3553773 ACon1_002096 CC/C=C\[C@H](O)[C@H](O)C1=C(C)C(=O)[C@@]2(O1)C(O)[C@](NC2=O)(OC)C(=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I19 compound treatment 192120.0 19400.0 0.52 194400.0 15600.0 0.42 0.6649 0.9948 3616392 ACon1_002097 Cc1cc(O)c(O)c(c1)C(=O)C(=O)c2c(O)cc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I20 compound treatment 178200.0 5460.0 0.15 165320.0 -13500.0 -0.37 -0.155 -0.3942 3552073 ACon1_002098 C/C=C/C=C/C(=O)C1=C(O)C(=C(O)C(C)(O)C1=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I21 mock treatment 165840.0 -6910.0 -0.18 163160.0 -15600.0 -0.42 -0.4302 -0.9308 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I22 mock treatment 145160.0 -27600.0 -0.74 196400.0 17600.0 0.48 -0.185 -0.2106 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I23 compound treatment 201960.0 29200.0 0.78 193480.0 14700.0 0.4 0.8335 0.9508 3616393 ACon1_002099 C/C=C\1/C(CC(=O)OCCc2ccc(O)c(O)c2)C(=COC1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 I24 compound treatment 175400.0 2660.0 0.07 184800.0 5990.0 0.16 0.1649 0.9313 3553755 ACon1_002100 CC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J01 compound treatment 176360.0 3620.0 0.1 175440.0 -3370.0 -0.09 0.0039 0.0294 3616395 ACon1_002101 Oc1ccc(cc1)[C@H]2[C@@H]([C@@H]3[C@H](c4ccc(O)cc4)c5c(O)cc(O)cc5OC3=O)C(=O)Oc6cc(O)cc(O)c26 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J02 compound treatment 46400.0 -126000.0 -3.38 29720.0 -149000.0 -4.04 -5.2437 -0.9961 3559240 ACon1_002102 O[C@H]1[C@H]2[C@H](CC(=O)O)C(=O)O[C@@H]3C(COC(=O)c4cc(O)c(O)c(O)c4)O[C@@H](OC(=O)c5cc(O)c(O)c(O)c5)C(OC(=O)c6cc(O)c(O)c(OC1=O)c26)[C@@H]3OC(=O)c7cc(O)c(O)c(O)c7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J03 compound treatment 159680.0 -13100.0 -0.35 195640.0 16800.0 0.46 0.0751 0.1308 3616397 ACon1_002103 COc1cc(cc2cc(oc12)c3ccc4OCOc4c3)C(O)CCOC5OC(CO)C(O)C(O)C5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J04 compound treatment 164760.0 -7990.0 -0.21 204320.0 25500.0 0.69 0.3374 0.4666 3559759 ACon1_002104 CC[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c3ccnc4ccc(OC)cc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J05 mock treatment 165240.0 -7510.0 -0.2 184960.0 6150.0 0.17 -0.0242 -0.0927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J06 mock treatment 156800.0 -15900.0 -0.43 186920.0 8110.0 0.22 -0.1463 -0.305 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J07 compound treatment 194600.0 21900.0 0.58 165960.0 -12800.0 -0.35 0.1674 0.2461 3616398 ACon1_002105 Cc1cc2c(CO)cc(O)cc2o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J08 compound treatment 160800.0 -11900.0 -0.32 149400.0 -29400.0 -0.8 -0.7889 -0.9196 1066 ACon1_002106 OC1OCC=C2OC(=O)C=C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J09 compound treatment 27400.0 -145000.0 -3.89 25560.0 -153000.0 -4.15 -5.6827 -0.9995 3555011 ACon1_002107 COC1CC(OC2CCC3(C)C(CCC4C3CCC5(C)C(C(CC45O)OC(=O)C)C6=CC(=O)OC6)C2)OC(C)C1OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J10 compound treatment 155440.0 -17300.0 -0.46 184320.0 5510.0 0.15 -0.2218 -0.456 3558451 ACon1_002108 CC1=C2CCC(C)(O)C=C2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J11 compound treatment 163560.0 -9190.0 -0.25 187800.0 8990.0 0.24 -0.0016 -0.0046 3559926 ACon1_002109 CC1CCC(=C)/C(=C\C=C/CC1(C)CCC2=CCOC2=O)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J12 compound treatment 144240.0 -28500.0 -0.76 164120.0 -14700.0 -0.4 -0.8203 -0.9539 3559949 ACon1_002110 C/C=C(/C)\C(=O)OC(C)(C)C1Cc2cc3ccc(=O)oc3cc2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J13 compound treatment 48680.0 -124000.0 -3.32 51160.0 -128000.0 -3.46 -4.7902 -0.9998 3553079 ACon1_002111 C[C@H]1[C@H]2[C@@H](CC1=O)C(=C)C[C@@H](OC(=O)/C(=C/CO)/COC(=O)/C(=C/CO)/C)C3[C@@H]2OC(=O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J14 compound treatment 170120.0 -2630.0 -0.07 161840.0 -17000.0 -0.46 -0.3745 -0.8058 3083213 ACon1_002112 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc3ccc(O)cc32)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J15 compound treatment 167840.0 -4910.0 -0.13 165040.0 -13800.0 -0.37 -0.3563 -0.9018 3558672 ACon1_002113 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C/C=C/3\[C@H](O)COC3=O)C(=C)CC[C@H]12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J16 compound treatment 180680.0 7940.0 0.21 158960.0 -19800.0 -0.54 -0.2299 -0.3979 3559659 ACon1_002114 CC(=CCn1cnc(N)c2ncnc12)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J17 compound treatment 159360.0 -13400.0 -0.36 157720.0 -21100.0 -0.57 -0.6569 -0.9747 3141 ACon1_002115 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)/C=C/c6cc(OC)c(OC)c(OC)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J18 compound treatment 156440.0 -16300.0 -0.44 145280.0 -33500.0 -0.91 -0.9502 -0.9436 2107849 ACon1_002116 C[C@@H]1CCC(=C)/C(=C\C=C/C[C@@]1(C)CCc2ccoc2)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J19 compound treatment 169200.0 -3550.0 -0.09 169640.0 -9170.0 -0.25 -0.2426 -0.9129 1054600 ACon1_002117 COc1cc(C=O)cc2c3ccccc3[nH]c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J20 compound treatment 156560.0 -16200.0 -0.43 196640.0 17800.0 0.48 0.0352 0.0543 1024517 ACon1_002118 COc1cc2CCNC(C)c2cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J21 mock treatment 184480.0 11700.0 0.31 164760.0 -14000.0 -0.38 -0.047 -0.0952 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J22 mock treatment 163040.0 -9710.0 -0.26 175400.0 -3410.0 -0.09 -0.2488 -0.9031 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J23 compound treatment 161000.0 -11700.0 -0.31 164480.0 -14300.0 -0.39 -0.4964 -0.9945 1528803 ACon1_002119 CC1(C)C2(C)CCC1(OC2=O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 J24 compound treatment 204480.0 31700.0 0.85 190400.0 11600.0 0.31 0.8222 0.9084 3559578 ACon1_002120 COC(=O)/C=C(/CC[C@@H]1C(=C)CC[C@@H]2C(C)(C)C[C@@H](O)C[C@@]12C)\COC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K01 compound treatment 177720.0 4980.0 0.13 174080.0 -4730.0 -0.13 0.0036 0.0195 3553784 ACon1_002121 CC[C@@H]1[C@@H](O)N2[C@H]3C[C@@]45C(O)C3C1CC2[C@@H]5N(C)c6ccccc64 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K02 compound treatment 143960.0 -28800.0 -0.77 150800.0 -28000.0 -0.76 -1.0806 -1.0 3557326 ACon1_002122 CC[C@H](C)[C@H]1NC(=O)[C@@H]2C[C@@]3([C@@H](Nc4ccccc43)N2C1=O)C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K03 compound treatment 174360.0 1620.0 0.04 162240.0 -16600.0 -0.45 -0.2866 -0.6361 3558174 ACon1_002123 CC(O)CCC1=CCC2C(CC1C)OC(=O)C2=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K04 compound treatment 229400.0 56700.0 1.52 198120.0 19300.0 0.52 1.4413 0.8991 3559931 ACon1_002124 CC(=O)NCCCN(CCCCN(CCCNC(=O)/C=C/c1ccc(O)cc1)C(=O)C)C(=O)/C=C/c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K05 compound treatment 169640.0 -3110.0 -0.08 167280.0 -11500.0 -0.31 -0.2794 -0.8652 3552912 ACon1_002125 C[C@]12O[C@@H]2CC3C(C)(C)CCC[C@]3(C)[C@]41CC[C@](C)(CC(=O)O)O4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K06 compound treatment 158000.0 -14700.0 -0.39 174920.0 -3890.0 -0.11 -0.3533 -0.8655 3616399 ACon1_002126 COc1c(C2OCC(OC(=O)C)C(OC(=O)C)C2OC(=O)C)c(O)cc3oc(cc(=O)c13)c4ccc(OC5OC(CO)C(O)C(O)C5O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K07 mock treatment 159080.0 -13700.0 -0.37 181520.0 2710.0 0.07 -0.2065 -0.554 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K08 mock treatment 176680.0 3940.0 0.11 187480.0 8670.0 0.23 0.2404 0.9345 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K09 compound treatment 177880.0 5140.0 0.14 173520.0 -5290.0 -0.14 -0.0041 -0.0207 3616400 ACon1_002127 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K10 compound treatment 177600.0 4860.0 0.13 185160.0 6350.0 0.17 0.2134 0.9904 3616402 ACon1_002128 CC1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6O)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K11 compound treatment 185400.0 12700.0 0.34 174240.0 -4570.0 -0.12 0.1519 0.4215 3616404 ACon1_002129 CC(C)C1CCC(=C2CCC(=CC12)C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K12 compound treatment 20960.0 -152000.0 -4.06 17560.0 -161000.0 -4.37 -5.9577 -0.9993 3616405 ACon1_002130 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(CO)[C@@H](CC[C@@H]4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K13 compound treatment 86480.0 -86300.0 -2.31 77240.0 -102000.0 -2.75 -3.576 -0.9962 3616407 ACon1_002131 C[C@@H]1[C@@H](C)c2ncccc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)c6ccccc6)[C@@H](O)[C@H](OC1=O)[C@]4(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K14 compound treatment 167200.0 -5550.0 -0.15 170560.0 -8250.0 -0.22 -0.2628 -0.9803 3616409 ACon1_002132 CCN1C[C@]2(C)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@](O)(C[C@@H]5OC)[C@]6(O)[C@@H](OC)C32)[C@H]16 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K15 mock treatment 190640.0 17900.0 0.48 187520.0 8710.0 0.24 0.5052 0.9468 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K16 mock treatment 164080.0 -8670.0 -0.23 157840.0 -21000.0 -0.57 -0.5653 -0.9219 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K17 compound treatment 129400.0 -43300.0 -1.16 119040.0 -59800.0 -1.62 -1.964 -0.9866 3616411 ACon1_002133 CC(CO)C(=O)O[C@H]1CC(C)(C=C)C([C@H]2OC(=O)C(=C)[C@@H]21)C(=C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K18 compound treatment 171960.0 -785.0 -0.02 188600.0 9790.0 0.27 0.1726 0.6491 3616413 ACon1_002134 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K19 compound treatment 200960.0 28200.0 0.75 182240.0 3430.0 0.09 0.5994 0.7882 3616414 ACon1_002135 CC(C)(O)/C=C/C1=CC(O)C(C)(O)CC1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K20 compound treatment 173360.0 615.0 0.02 171680.0 -7130.0 -0.19 -0.1248 -0.6445 3557979 ACon1_002136 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C1CC(O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K21 compound treatment 171400.0 -1350.0 -0.04 163880.0 -14900.0 -0.4 -0.3112 -0.767 1116462 ACon1_002137 Nc1c(O)cccc1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K22 compound treatment 155960.0 -16800.0 -0.45 175800.0 -3010.0 -0.08 -0.3751 -0.8219 3559068 ACon1_002138 COc1cc(cc(OC)c1OC)C2OC(C(C)C2C)c3cc(OC)c(OC)c(OC)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K23 mock treatment 176600.0 3860.0 0.1 166680.0 -12100.0 -0.33 -0.1593 -0.4627 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 K24 mock treatment 184920.0 12200.0 0.33 187360.0 8550.0 0.23 0.394 0.986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L01 compound treatment 171160.0 -1590.0 -0.04 174920.0 -3890.0 -0.11 -0.1044 -0.9201 3615597 ACon1_002139 COC1OC(=O)C(CCC2(C)C(C)CCC3(C)C2CC(O)C(O)C43CO4)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L02 compound treatment 71120.0 -102000.0 -2.72 72560.0 -106000.0 -2.88 -3.9561 -0.9996 3557877 ACon1_002140 OC[C@H]1O[C@@H](OC(CCc2ccc(O)cc2)CC(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L03 compound treatment 174320.0 1580.0 0.04 179160.0 352.0 0.01 0.0365 0.8457 3616416 ACon1_002141 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)[C@@H](OC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L04 compound treatment 173280.0 535.0 0.01 183640.0 4830.0 0.13 0.1026 0.7798 1091317 ACon1_002142 CC(C)CC(=O)CC1(C)CCC(O1)c2ccoc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L05 compound treatment 178280.0 5540.0 0.15 195200.0 16400.0 0.44 0.4185 0.8945 3616418 ACon1_002143 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccc(O)cc6)[C@H](OC(=O)C)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L06 compound treatment 14400.0 -158000.0 -4.24 12720.0 -166000.0 -4.5 -6.1744 -0.9996 3552811 ACon1_002144 C[C@@H]1OC(CC[C@@H]1O)O[C@@]23C(=O)C[C@](C)(O)C[C@@]3(O)C=CC4=C2C(=O)c5ccc([C@H]6C[C@@H](O[C@H]7CC[C@H](O[C@H]8C[C@@H](O)[C@H](O)[C@@H](C)O8)[C@H](C)O7)[C@H](O)[C@@H](C)O6)c(O)c5C4=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L07 mock treatment 177240.0 4500.0 0.12 155440.0 -23400.0 -0.63 -0.3623 -0.5626 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L08 mock treatment 171520.0 -1230.0 -0.03 183200.0 4390.0 0.12 0.0609 0.4938 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L09 compound treatment 181400.0 8660.0 0.23 176800.0 -2010.0 -0.05 0.1253 0.5268 3558762 ACon1_002145 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L10 compound treatment 180360.0 7620.0 0.2 176000.0 -2810.0 -0.08 0.0903 0.4152 3558525 ACon1_002146 COC(=O)CCCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L11 compound treatment 194000.0 21300.0 0.57 197240.0 18400.0 0.5 0.7549 0.9979 3558176 ACon1_002147 COc1cc(O)c2C(=O)[C@H](OC(=O)C)[C@H](Oc2c1)c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L12 compound treatment 176040.0 3300.0 0.09 154320.0 -24500.0 -0.66 -0.4065 -0.6078 3554563 ACon1_002148 COC(=O)[C@]12C(=O)C(C)C(=O)[C@]2(C)C(=C[C@@H]3[C@]1(C)CC[C@@H]4C(C)(C)[C@H](CC[C@]43CO)OC(=O)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L13 compound treatment 19120.0 -154000.0 -4.11 16600.0 -162000.0 -4.39 -6.0109 -0.9994 3559438 ACon1_002149 CC(C)CC(=O)OC1C(Oc2ccc3ccc(=O)oc3c12)C(C)(C)OC(=O)CC(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L14 compound treatment 173120.0 375.0 0.01 188000.0 9190.0 0.25 0.1831 0.735 3559513 ACon1_002150 C[C@]1(C[C@]23CCC4[C@](C)(CO)CCC[C@@]4(C)C3CC1)C=C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L15 mock treatment 184200.0 11500.0 0.31 152360.0 -26400.0 -0.72 -0.2896 -0.3719 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L16 mock treatment 180160.0 7420.0 0.2 143520.0 -35300.0 -0.96 -0.5353 -0.5486 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L17 compound treatment 168520.0 -4230.0 -0.11 150720.0 -28100.0 -0.76 -0.6176 -0.8034 3173755 ACon1_002151 C[C@@]12CC(=O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L18 compound treatment 163840.0 -8910.0 -0.24 160760.0 -18000.0 -0.49 -0.5139 -0.9455 3553165 ACon1_002152 CC#CC#C/C=C\1/OC2(OC=CC2OC(=O)C=C(C)C)C=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L19 compound treatment 36480.0 -136000.0 -3.64 33800.0 -145000.0 -3.93 -5.3533 -0.9993 3616420 ACon1_002153 COc1cc(O)c(O)c(OC)c1C(=O)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L20 compound treatment 163640.0 -9110.0 -0.24 152160.0 -26600.0 -0.72 -0.6823 -0.8961 3557450 ACon1_002154 C[C@@]12CCC3[C@@H](CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L21 compound treatment 169720.0 -3030.0 -0.08 181800.0 2990.0 0.08 1.0E-4 6.0E-4 1023016 ACon1_002155 COc1ccc2ccc(=O)oc2c1CC=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L22 compound treatment 162280.0 -10500.0 -0.28 154680.0 -24100.0 -0.65 -0.6598 -0.9285 3557458 ACon1_002156 C[C@@]12CCC3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)C2CC[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L23 mock treatment 169880.0 -2870.0 -0.08 172640.0 -6170.0 -0.17 -0.1723 -0.9376 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 L24 mock treatment 190600.0 17900.0 0.48 156480.0 -22300.0 -0.6 -0.0897 -0.1165 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M01 compound treatment 173680.0 935.0 0.03 162160.0 -16600.0 -0.45 -0.301 -0.6668 3555864 ACon1_002157 OC(=O)CCCCCCCC(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M02 compound treatment 11400.0 -161000.0 -4.32 8920.0 -170000.0 -4.6 -6.3039 -0.9995 3616422 ACon1_002158 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M03 compound treatment 102880.0 -69900.0 -1.87 59920.0 -119000.0 -3.22 -3.5973 -0.9666 3557282 ACon1_002159 C[C@@H]1O[C@@H](Oc2ccc(cc2)c3coc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)ccc4c3=O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M04 compound treatment 140080.0 -32700.0 -0.87 121280.0 -57500.0 -1.56 -1.7191 -0.9627 3553312 ACon1_002160 CC(=O)NC1CCCN(O)C(=O)/C=C(\C)/CCOC(=O)C(CCCN(O)C(=O)/C=C(\C)/CCOC(=O)C(CCCN(O)C(=O)/C=C(\C)/CCOC1=O)NC(=O)C)NC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M05 compound treatment 78080.0 -94700.0 -2.53 50640.0 -128000.0 -3.47 -4.2441 -0.988 3553564 ACon1_002161 CC(C)c1cc2C(O)[C@H]3OC(=O)[C@@]4(CCCC(C)(C)C34)c2c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M06 compound treatment 199760.0 27000.0 0.72 186440.0 7630.0 0.21 0.6571 0.8743 3616424 ACon1_002162 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M07 compound treatment 157640.0 -15100.0 -0.4 156280.0 -22500.0 -0.61 -0.717 -0.98 3616426 ACon1_002163 CC1CC(=O)C2C(O)(C1)CC(O)C34OC4c5c(O)cccc5C(=O)C23O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M08 compound treatment 179960.0 7220.0 0.19 181440.0 2630.0 0.07 0.1869 0.9083 3616427 ACon1_002164 CC(=O)OC(C)(C)/C=C/C(=O)[C@](C)(O)[C@H]1C(O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M09 mock treatment 177000.0 4260.0 0.11 169600.0 -9210.0 -0.25 -0.0958 -0.3495 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M10 mock treatment 204360.0 31600.0 0.85 217120.0 38300.0 1.04 1.3314 0.9949 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M11 compound treatment 175320.0 2580.0 0.07 176040.0 -2770.0 -0.07 -0.0043 -0.0421 3616429 ACon1_002165 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)[C@@H](OC(=O)/C=C/c4ccc(O)cc4)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M12 compound treatment 160920.0 -11800.0 -0.32 146440.0 -32400.0 -0.88 -0.8433 -0.9052 3616431 ACon1_002166 COc1c(O)cc2oc(cc(=O)c2c1O)c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M13 mock treatment 176560.0 3820.0 0.1 184360.0 5550.0 0.15 0.1784 0.9822 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M14 mock treatment 195120.0 22400.0 0.6 162960.0 -15800.0 -0.43 0.1198 0.1627 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M15 compound treatment 211000.0 38300.0 1.02 163720.0 -15100.0 -0.41 0.4347 0.3946 3616433 ACon1_002167 CC1OC(OC2C(O)C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)C(O)CC7(C(O)CC65C)C(=O)O)C3(C)C)OC2CO)C(O)C(OC8OCC(O)C(O)C8O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M16 compound treatment 194160.0 21400.0 0.57 151160.0 -27600.0 -0.75 -0.1242 -0.1318 3616434 ACon1_002168 CC(C)[C@H](NC(=O)[C@H](C)N(C)C)C(=O)N1CC[C@@H]2Oc3ccc(/C=C\NC(=O)[C@H](Cc4ccccc4)NC(=O)C21)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M17 compound treatment 195720.0 23000.0 0.61 196120.0 17300.0 0.47 0.766 0.9911 3616436 ACon1_002169 CC1(CO)CC(=O)CC2(C)C1CCC3=C2COC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M18 compound treatment 149200.0 -23500.0 -0.63 170000.0 -8810.0 -0.24 -0.6139 -0.9117 3554069 ACon1_002170 CC1CCC2C(C)(C)C(=O)CC[C@]2(C)C31Cc4c(O3)c5CN(C(CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M19 compound treatment 153400.0 -19300.0 -0.52 151640.0 -27200.0 -0.74 -0.886 -0.9852 3616437 ACon1_002171 CCCc1c(O)c2C(=O)c3c(O)cccc3C(=O)c2cc1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M20 compound treatment 176960.0 4220.0 0.11 155040.0 -23800.0 -0.64 -0.3753 -0.5745 3555795 ACon1_002172 O=C1NC2CCc3nc4ccccc4c(=O)n3C2=Nc5ccccc15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M21 compound treatment 168000.0 -4750.0 -0.13 172040.0 -6770.0 -0.18 -0.2193 -0.9839 3616438 ACon1_002173 O[C@H]1[C@H](O)[C@@H](COC(=O)c2ccc(O)cc2)O[C@@H](Oc3ccc(O)cc3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M22 compound treatment 149560.0 -23200.0 -0.62 153040.0 -25800.0 -0.7 -0.9318 -0.9983 3554747 ACon1_002174 COC1=CC(=O)CC(C)C21Oc3cc(OC)cc(OC)c3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M23 compound treatment 173400.0 655.0 0.02 191000.0 12200.0 0.33 0.2458 0.7436 3554983 ACon1_002175 COc1cc(O)c2C(=O)O[C@@]3(C)C[C@H](O)[C@@H](O)C=C3c2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 M24 compound treatment 28960.0 -144000.0 -3.85 22320.0 -156000.0 -4.24 -5.7153 -0.9988 3616440 ACon1_002176 Oc1ccc(CCCCC(=O)CCc2ccc(O)c(O)c2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N01 compound treatment 184520.0 11800.0 0.31 200600.0 21800.0 0.59 0.6399 0.9568 3616441 ACon1_002177 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3C=C(CO)[C@@H]4[C@H]3C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H]2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N02 compound treatment 92800.0 -79900.0 -2.14 79480.0 -99300.0 -2.69 -3.4135 -0.9936 3557494 ACon1_002178 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N03 compound treatment 32480.0 -140000.0 -3.75 11520.0 -167000.0 -4.53 -5.8554 -0.9956 3616443 ACon1_002179 C[C@@H]1[C@H]2[C@@H](CC1=O)C(=C)C[C@H](OC(=O)C(=C)CO)[C@@H]3[C@@H]2OC(=O)C3=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N04 compound treatment 176320.0 3580.0 0.1 180520.0 1710.0 0.05 0.1004 0.9447 3553392 ACon1_002180 CC(=O)OCC#Cc1ccc(s1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N05 compound treatment 12880.0 -160000.0 -4.28 10680.0 -168000.0 -4.55 -6.2422 -0.9995 3616445 ACon1_002181 C[C@@H]1CCOC(=O)/C=C/C=C\C(=O)O[C@@H]2C[C@H]3O[C@@H]4C=C(CC[C@]4(COC(=O)[C@H]1O)[C@]2(C)[C@@]53CO5)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N06 compound treatment 166440.0 -6310.0 -0.17 168200.0 -10600.0 -0.29 -0.3223 -0.9678 3559417 ACon1_002182 COC(=O)[C@@]1(C)CCC[C@]2(C)[C@@H](CCC3=CC(=O)OC3)C(=CC[C@@H]12)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N07 compound treatment 173480.0 735.0 0.02 167080.0 -11700.0 -0.32 -0.2106 -0.6621 3616447 ACon1_002183 CNc1ccccc1C(=O)OC2OC(C)C(O)C(O)C2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N08 compound treatment 162520.0 -10200.0 -0.27 185240.0 6430.0 0.17 -0.0703 -0.2167 3559635 ACon1_002184 CC(=CC(O)C/C(=C\CCC(C)(O)C=C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N09 mock treatment 175800.0 3060.0 0.08 175840.0 -2970.0 -0.08 0.001 0.0085 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N10 mock treatment 193320.0 20600.0 0.55 158600.0 -20200.0 -0.55 0.0023 0.003 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N11 compound treatment 170920.0 -1830.0 -0.05 181800.0 2990.0 0.08 0.0228 0.2407 3616448 ACon1_002185 CCC[C@@H](O)[C@H](O)[C@@H]1CC(=CC(=O)O1)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N12 compound treatment 228040.0 55300.0 1.48 208840.0 30000.0 0.81 1.6208 0.9603 3558517 ACon1_002186 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N13 mock treatment 177240.0 4500.0 0.12 202480.0 23700.0 0.64 0.5382 0.8254 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N14 mock treatment 179760.0 7020.0 0.19 200880.0 22100.0 0.6 0.5552 0.8865 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N15 compound treatment 17520.0 -155000.0 -4.15 13840.0 -165000.0 -4.47 -6.094 -0.9993 3557442 ACon1_002187 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)CCC3=C)\CCC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N16 compound treatment 201320.0 28600.0 0.76 144760.0 -34000.0 -0.92 -0.1113 -0.093 3552715 ACon1_002188 C[C@@H]1CCC2[C@@H](C)C(=O)OC3O[C@@]4(C)CCC1[C@@]23OO4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N17 compound treatment 173840.0 1100.0 0.03 164960.0 -13800.0 -0.37 -0.2444 -0.6499 3557445 ACon1_002189 CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N18 compound treatment 203360.0 30600.0 0.82 182320.0 3510.0 0.1 0.6463 0.7839 3559502 ACon1_002190 COC(=O)[C@]1(C)CCC[C@@]2(C)C3CC[C@@H]4C[C@]3(CC4=C)CCC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N19 compound treatment 228200.0 55500.0 1.48 229320.0 50500.0 1.37 2.0159 0.9992 3559390 ACon1_002191 Oc1ccc2C(=O)C(C(Oc2c1)c3ccc(O)c(O)c3)C4C(Oc5cc(O)ccc5C4=O)c6ccc(O)c(O)c6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N20 compound treatment 187520.0 14800.0 0.4 218920.0 40100.0 1.09 1.0473 0.9063 3559784 ACon1_002192 O=C1/C(=C/2\Nc3ccccc3C2=O)/Nc4ccccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N21 compound treatment 153200.0 -19500.0 -0.52 146520.0 -32300.0 -0.87 -0.9878 -0.9698 1090111 ACon1_002193 CC(=C)C1Cc2cc(ccc2O1)C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N22 compound treatment 183080.0 10300.0 0.28 155920.0 -22900.0 -0.62 -0.2427 -0.3577 3557455 ACon1_002194 C[C@@]12CCC3[C@@H](CCC4=CC(=O)C=C[C@]34C)C2CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N23 compound treatment 190040.0 17300.0 0.46 158920.0 -19900.0 -0.54 -0.0536 -0.0755 3553947 ACon1_002195 CC1=CCC[C@]2(C)CC[C@H](C[C@@H]12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 N24 compound treatment 193120.0 20400.0 0.55 185960.0 7150.0 0.19 0.5223 0.903 1737132 ACon1_002196 COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c2c34)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O01 compound treatment 167000.0 -5750.0 -0.15 163960.0 -14800.0 -0.4 -0.3929 -0.913 3554295 ACon1_002197 CCCCCCCC1OC(=O)CCC(O)/C=C/C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O02 compound treatment 153880.0 -18900.0 -0.5 154160.0 -24600.0 -0.67 -0.8287 -0.9905 3616449 ACon1_002198 CC1C(O)C=C2[C@@H](CC[C@@]3(O)[C@](C)([C@H](O)CC[C@]23C)C(=O)O)[C@H]1C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O03 compound treatment 127960.0 -44800.0 -1.2 132640.0 -46200.0 -1.25 -1.7309 -0.9998 3558022 ACon1_002199 C/C/1=C\[C@H](O)C2[C@H](OC(=O)C2=C)/C=C(\CO)/CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O04 compound treatment 134160.0 -38600.0 -1.03 147480.0 -31300.0 -0.85 -1.3295 -0.9952 3616451 ACon1_002200 CC(=O)N(O)CCCCCNC(=O)CC(O)(CC(=O)NCCCCCN(O)C(=O)C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O05 compound treatment 13080.0 -160000.0 -4.27 10760.0 -168000.0 -4.55 -6.2369 -0.9995 3616452 ACon1_002201 CCC/C=C/C(=O)OC1C(O)C2(C(O)OC34CCC5C6(C)CCC(OC7OC(C(O)C(OC8OC(CO)C(O)C(O)C8OC9OC(C)C(O)C(O)C9OC%10OCC(O)C(O)C%10O)C7OC%11OC(CO)C(O)C(O)C%11O)C(=O)O)C(C)(C)C6CCC5(C)C4(C)CC2OC(=O)C)C3CC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O06 compound treatment 193800.0 21100.0 0.56 187160.0 8350.0 0.23 0.5581 0.9196 3616299 ACon1_002202 COC(=O)Cc1c(oc2cc(C)cc(O)c2c1=O)C(=CC(=O)O)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O07 compound treatment 160400.0 -12300.0 -0.33 151680.0 -27100.0 -0.73 -0.7528 -0.9349 3616454 ACon1_002203 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)[C@@H]2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O08 compound treatment 148280.0 -24500.0 -0.65 147160.0 -31600.0 -0.86 -1.0686 -0.9912 3616455 ACon1_002204 OC[C@H]1O[C@@H](Oc2c(O)cccc2COC(=O)C3(O)C4C=CC(C5C4C=CC(=O)C5(O)C(=O)OCc6cccc(O)c6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C3=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O09 compound treatment 164200.0 -8550.0 -0.23 183440.0 4630.0 0.13 -0.0729 -0.2798 3616458 ACon1_002205 COc1cc(O)c(C(=O)c2c(O)cc(C)cc2O)c(c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O10 compound treatment 154560.0 -18200.0 -0.49 165320.0 -13500.0 -0.37 -0.6022 -0.99 1063449 ACon1_002206 COc1c(C)c(OCC=C(C)C)cc(CO)c1CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O11 mock treatment 183480.0 10700.0 0.29 162440.0 -16400.0 -0.44 -0.1103 -0.2089 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O12 mock treatment 167360.0 -5390.0 -0.14 157160.0 -21600.0 -0.59 -0.5163 -0.8554 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O13 compound treatment 150600.0 -22100.0 -0.59 163360.0 -15400.0 -0.42 -0.7146 -0.9855 3616460 ACon1_002207 C[C@H](CO)C1=C(O)C(=O)[C@@]2(C)C/C=C(\C)/CC/C=C(\C)/CC[C@H](O)\C(=C\C[C@H]12)\C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O14 compound treatment 188320.0 15600.0 0.42 154400.0 -24400.0 -0.66 -0.1727 -0.221 3616463 ACon1_002208 OC[C@H]1O[C@@H](OC2OC=C3C(CC4N(CCc5c4[nH]c6ccccc56)C3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O15 compound treatment 185520.0 12800.0 0.34 202520.0 23700.0 0.64 0.6956 0.9564 3616464 ACon1_002209 CC1OC(OC2C(O)C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)C8CC7(C(O)CC65C)C(=O)O8)C3(C)C)OC2CO)C(O)C(OC9OCC(O)C(O)C9O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O16 compound treatment 218480.0 45700.0 1.22 173400.0 -5410.0 -0.15 0.7615 0.6181 3616465 ACon1_002210 COC1OC2C(c3ccc4OCOc4c13)[N+](C)([O-])CCc5cc6OCOc6cc25 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O17 compound treatment 200280.0 27500.0 0.74 175320.0 -3490.0 -0.09 0.454 0.6114 3616466 ACon1_002211 CCC(C)C(O)(CC(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)C(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O18 compound treatment 184040.0 11300.0 0.3 154040.0 -24800.0 -0.67 -0.2605 -0.3542 3616469 ACon1_002212 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O19 compound treatment 189560.0 16800.0 0.45 185640.0 6830.0 0.18 0.4488 0.9229 3616471 ACon1_002213 CC(C)CC1NC(=O)C2(O)C1C(C)C(=CC2/C=C(\C)/CCC(O)C(O)/C=C/C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O20 compound treatment 189440.0 16700.0 0.45 216840.0 38000.0 1.03 1.0438 0.9301 3554660 ACon1_002214 COC(=O)C1(Cc2ccc(O)c(CC3OC3(C)C)c2)OC(=O)C(=C1c4ccc(O)cc4)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O21 compound treatment 182080.0 9340.0 0.25 221360.0 42600.0 1.15 0.9911 0.8408 3616474 ACon1_002215 C[C@H](CC/C=C(\C)/C(=O)OC1OC(CO)C(O)C(O)C1O)[C@H]2CC(OC3OCC(O)C(O)C3O)[C@@]4(C)C5CC[C@@H]6[C@]7(C[C@@]57CC(O)[C@]24C)CC[C@H](O[C@@H]8OC(CO)C(O)C(O)C8OC9OC(CO)C(O)C(O)C9O)C6(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O22 compound treatment 190200.0 17500.0 0.47 158040.0 -20800.0 -0.56 -0.0674 -0.0922 3558516 ACon1_002216 COC(=O)C(C(O)c1ccc(O)c(OC)c1)C(CO)Cc2ccc(O)c(OC)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O23 compound treatment 32640.0 -140000.0 -3.75 16840.0 -162000.0 -4.38 -5.7506 -0.9969 3616477 ACon1_002217 COC1(C)C(O)C(=O)C(=C(Oc2cc(C)c(C(=O)NCCc3ccc(O)c(O)c3)c(O)c2C)C1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 O24 compound treatment 218680.0 45900.0 1.23 179360.0 552.0 0.01 0.8794 0.7157 3616478 ACon1_002218 CC1CCC2(C)C(CC(O)C(O)C32CO3)C1(C)CCC4=CC(=O)OC4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P01 compound treatment 173640.0 895.0 0.02 175120.0 -3690.0 -0.1 -0.0537 -0.5227 3616479 ACon1_002219 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)O)OC(=O)CCc4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P02 compound treatment 163000.0 -9750.0 -0.26 177640.0 -1170.0 -0.03 -0.2067 -0.7871 3559761 ACon1_002220 CS(=O)(=O)CCC/C(=N\OS(=O)(=O)O)/S[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P03 compound treatment 182320.0 9580.0 0.26 166960.0 -11800.0 -0.32 -0.0457 -0.1113 3616481 ACon1_002221 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](OC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H](O)[C@@H]31 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P04 compound treatment 171160.0 -1590.0 -0.04 162800.0 -16000.0 -0.43 -0.3364 -0.7726 3559446 ACon1_002222 COc1cc2OC(C)(C)C=Cc2cc1C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P05 compound treatment 194480.0 21700.0 0.58 180640.0 1830.0 0.05 0.4462 0.7647 3558885 ACon1_002223 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](C=C)[C@@H]1C[C@@H]3N[C@@H](Cc4c3[nH]c5ccccc45)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P06 compound treatment 190960.0 18200.0 0.49 164960.0 -13800.0 -0.37 0.0794 0.1292 3558178 ACon1_002224 CC1(O)CCCC2(C)CCC(CC12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P07 compound treatment 184120.0 11400.0 0.3 157040.0 -21800.0 -0.59 -0.2016 -0.3039 3558887 ACon1_002225 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P08 compound treatment 217960.0 45200.0 1.21 151800.0 -27000.0 -0.73 0.3382 0.2393 3559717 ACon1_002226 CC1(C)CC(=O)c2ccc(O)cc2O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P09 compound treatment 169360.0 -3390.0 -0.09 145320.0 -33500.0 -0.91 -0.7051 -0.7739 3559894 ACon1_002227 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CCC4[C@@]5(C)CCC(=O)C(C)(C)C5C(O)C[C@]43C)C12)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P10 compound treatment 206640.0 33900.0 0.91 176120.0 -2690.0 -0.07 0.5896 0.6483 3557753 ACon1_002228 CC(O)/C=C/C1(O)C(=CC(=O)CC1(C)C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P11 mock treatment 191680.0 18900.0 0.51 159360.0 -19400.0 -0.53 -0.0142 -0.0194 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P12 mock treatment 181960.0 9220.0 0.25 170320.0 -8490.0 -0.23 0.0118 0.035 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P13 compound treatment 182000.0 9260.0 0.25 162400.0 -16400.0 -0.44 -0.139 -0.2734 3552932 ACon1_002229 C[C@H](CCCC(C)(C(=O)O)C(=O)O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P14 compound treatment 163560.0 -9190.0 -0.25 136920.0 -41900.0 -1.13 -0.9756 -0.8408 3553129 ACon1_002230 C[C@H]1CC[C@@H]2[C@@H](OC(=O)C2=C)[C@@]3(C)[C@H]1C=CC3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P15 compound treatment 63360.0 -109000.0 -2.93 63120.0 -116000.0 -3.13 -4.2836 -0.9994 346 ACon1_002231 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)[C@@H]4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P16 compound treatment 198000.0 25300.0 0.68 152760.0 -26000.0 -0.71 -0.021 -0.0215 3552697 ACon1_002232 C[C@@H]1CC[C@@H]2[C@@H]1[C@H]3[C@@H](CCC2(O)CO)C3(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P17 compound treatment 179800.0 7060.0 0.19 163680.0 -15100.0 -0.41 -0.1562 -0.3463 3557610 ACon1_002233 O[C@H]1[C@H](O)[C@@H](OC(=O)c2ccc(O)cc2)[C@H](Oc3ccc(O)cc3)O[C@@H]1COC(=O)CC(=O)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P18 compound treatment 101440.0 -71300.0 -1.91 10880.0 -168000.0 -4.55 -4.5634 -0.9256 3559496 ACon1_002234 COC(=O)C[C@H](C)CC[C@H]1[C@](C)(O)CCC2C(C)(C)CCC[C@]12C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P19 compound treatment 169000.0 -3750.0 -0.1 151560.0 -27200.0 -0.74 -0.5924 -0.7958 3554682 ACon1_002235 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@H](C[C@@H]31)OC(=O)C4=CO[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H]6[C@@H](C)[C@H](C[C@@H]64)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P20 compound treatment 146000.0 -26700.0 -0.72 132280.0 -46500.0 -1.26 -1.3966 -0.9641 3557448 ACon1_002236 C[C@@]12CCC3[C@@H](CCc4cc(O)ccc34)C2CC[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P21 compound treatment 162400.0 -10300.0 -0.28 173800.0 -5010.0 -0.14 -0.2915 -0.9461 3559463 ACon1_002237 C/C(=C\CCC(C)(O)C=C)/CCC(O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P22 compound treatment 141640.0 -31100.0 -0.83 149760.0 -29000.0 -0.79 -1.1444 -0.9996 3557457 ACon1_002238 C[C@@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C2CC[C@@H]1C(=O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P23 compound treatment 172280.0 -465.0 -0.01 152720.0 -26100.0 -0.71 -0.5082 -0.7194 3559434 ACon1_002239 CCCCCCCCCCCC=C=CCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2296 P24 compound treatment 200080.0 27300.0 0.73 175800.0 -3010.0 -0.08 0.4594 0.6245 3559647 ACon1_002240 COc1ccc2C(=O)/C(=C/c3ccccc3)/Oc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A01 compound treatment 8240.0 -162000.0 -4.33 10360.0 -171000.0 -4.64 -6.3434 -0.9994 3552712 ACon1_002241 C[C@@H]1CCC/C=C/[C@H]2C[C@@H](O)C[C@@H]2[C@@H](O)/C=C/C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A02 compound treatment 215240.0 45200.0 1.21 264480.0 82700.0 2.24 2.4365 0.9581 3559403 ACon1_002242 O=CNCCc1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A03 compound treatment 220840.0 50800.0 1.36 253800.0 72000.0 1.95 2.338 0.9844 1060832 ACon1_002243 OCC(Cc1ccccc1)NC(=O)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A04 compound treatment 273400.0 103000.0 2.76 297880.0 116000.0 3.14 4.176 0.998 3555658 ACon1_002244 O=C(N[C@H](COC(=O)[C@H](Cc1ccccc1)NC(=O)c2ccccc2)Cc3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A05 compound treatment 212800.0 42700.0 1.14 236880.0 55100.0 1.49 1.862 0.9914 3554875 ACon1_002245 COc1cc(ccc1O)[C@H]2[C@H]3COC4(O)[C@H]3C(=CC2C4=O)[C@H]5Oc6cc(O)cc(O)c6C(=O)[C@@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A06 compound treatment 8920.0 -161000.0 -4.31 12640.0 -169000.0 -4.58 -6.2869 -0.9995 1032994 ACon1_002246 O=C1CC(Oc2ccccc12)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A07 compound treatment 22920.0 -147000.0 -3.94 57440.0 -124000.0 -3.37 -5.1645 -0.997 3559373 ACon1_002247 C/C=C(\C)/C(=O)O[C@@H]1[C@H](OC(=O)C)[C@@H](C)[C@](C)(CC(=O)c2ccoc2)C3CCC=C(C)[C@]13C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A08 compound treatment 220120.0 50000.0 1.34 234920.0 53100.0 1.44 1.963 0.9994 3557592 ACon1_002248 CC1(C)CCCC2(C)C(CCC(=C)C(O)CO)C(C)(O)CCC12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A09 compound treatment 71120.0 -99000.0 -2.65 106640.0 -75200.0 -2.04 -3.3109 -0.9916 3559707 ACon1_002249 COc1ccc2C=C(COc2c1)c3cc(O)c(O)cc3OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A10 compound treatment 215880.0 45800.0 1.23 196120.0 14300.0 0.39 1.14 0.8873 3559278 ACon1_002250 CC1=CC(=O)C[C@]2(C)CC[C@H](CC12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A11 compound treatment 192000.0 21900.0 0.59 253480.0 71700.0 1.94 1.7864 0.8814 3559492 ACon1_002251 C[C@@H]1CCC2C(=CC(=O)CC2(C)C)[C@@]1(C)CC/C(=C/CO)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A12 compound treatment 177200.0 7120.0 0.19 190040.0 8220.0 0.22 0.292 0.997 3616487 ACon1_002252 CC1OC(=O)CC2C(=CC3CC(C)(C)CC321)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A13 mock treatment 212760.0 42700.0 1.14 245560.0 63700.0 1.73 2.0274 0.9799 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A14 mock treatment 196760.0 26700.0 0.71 249040.0 67200.0 1.82 1.7914 0.9164 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A15 compound treatment 144160.0 -25900.0 -0.69 171400.0 -10400.0 -0.28 -0.6897 -0.9214 3616488 ACon1_002253 CON1c2ccccc2[C@]3(C=C(OC)C(=O)N4/C(=C/c5cnc[nH]5)/C(=O)N[C@@]143)C(C)(C)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A16 compound treatment 216200.0 46100.0 1.23 280680.0 98900.0 2.68 2.7648 0.9382 1637425 ACon1_002254 Cc1cc(O)c(Cc2c(O)cc(C)oc2=O)c(=O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A17 compound treatment 236920.0 66800.0 1.79 271200.0 89400.0 2.42 2.9752 0.9889 3558320 ACon1_002255 COc1cc(/C=C/C(=O)NCCCCNC(=O)C)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A18 compound treatment 238640.0 68600.0 1.83 228040.0 46200.0 1.25 2.1816 0.9826 3553473 ACon1_002256 CC(C)(O)C1=CCC2(COC3C2)C1CCC3(O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A19 compound treatment 221720.0 51600.0 1.38 282840.0 101000.0 2.73 2.9106 0.95 3558714 ACon1_002257 COc1cc(O)c2c(=O)c(O[C@@H]3O[C@@H](CO)[C@H](O)[C@H]3O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)c(oc2c1)c5ccc(O)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A20 compound treatment 10000.0 -160000.0 -4.28 13080.0 -169000.0 -4.57 -6.258 -0.9995 3616491 ACon1_002258 COc1cc(oc(=O)c1C)/C(=C/C(=C\C(=O)O)/C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A21 compound treatment 233480.0 63400.0 1.7 236800.0 55000.0 1.49 2.2516 0.9979 3559881 ACon1_002259 CC(=CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)C[C@H](Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A22 compound treatment 186840.0 16800.0 0.45 233640.0 51800.0 1.4 1.309 0.8888 3616494 ACon1_002260 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@H]3[C@H](O)[C@@H](CO)O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5C=C[C@@]78OC[C@@]9(CCC(C)(C)C[C@H]98)[C@@H](O)C[C@]76C)[C@]4(C)CO)[C@@H]3O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A23 compound treatment 218360.0 48300.0 1.29 220360.0 38500.0 1.04 1.651 0.9944 3552806 ACon1_002261 C[C@@H]1O[C@@H](OCC2OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC[C@@H]6C7[C@@](C)(O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@@H](CC=C(C)C)O[C@@]7(O)[C@H](O)[C@]65C)C3(C)C)C(O)C(O)C2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 A24 compound treatment 245160.0 75100.0 2.01 239120.0 57300.0 1.55 2.517 0.9919 1062887 ACon1_002262 CC1C(=O)c2cc3OCOc3cc2CCN(C)Cc4c5OCOc5ccc14 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B01 compound treatment 196360.0 26300.0 0.7 259040.0 77200.0 2.09 1.9753 0.8956 1047225 ACon1_002263 COC1C(O)CC2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC2C1C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B02 mock treatment 211840.0 41800.0 1.12 204600.0 22800.0 0.62 1.2259 0.9608 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B03 compound treatment 187120.0 17000.0 0.46 227520.0 45700.0 1.24 1.1971 0.9079 3559335 ACon1_002264 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)/C(=C\C)/C1CC(=O)OCC(CO)C3CC(OC(=O)CC4\C(=C\C)\C(OC5OC(CO)C(O)C(O)C5O)OC=C4C(=O)OC)C(C)C3COC(=O)CC6\C(=C\C)\C(OC7OC(CO)C(O)C(O)C7O)OC=C6C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B04 mock treatment 182000.0 11900.0 0.32 252320.0 70500.0 1.91 1.575 0.8139 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B05 compound treatment 165800.0 -4280.0 -0.11 201760.0 19900.0 0.54 0.3008 0.545 3616499 ACon1_002265 CO[C@@H]1[C@H](Oc2c(CC=C(C)C)c(O)c(CC=C(C)C)c(O)c2C1=O)c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B06 mock treatment 186800.0 16700.0 0.45 242840.0 61000.0 1.65 1.4844 0.8673 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B07 compound treatment 152200.0 -17900.0 -0.48 205760.0 23900.0 0.65 0.1201 0.1491 3616501 ACon1_002266 O[C@H]1[C@@H](C[C@@](O)(C[C@H]1OC(=O)/C=C/c2ccc(O)cc2)C(=O)O)OC(=O)/C=C/c3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B08 mock treatment 164520.0 -5560.0 -0.15 185240.0 3420.0 0.09 -0.0397 -0.2265 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B09 compound treatment 212520.0 42400.0 1.14 225920.0 44100.0 1.19 1.6469 0.9997 3616503 ACon1_002267 COC(=O)[C@]12O[C@@H]2[C@@H](C[C@H]3[C@]4(C)C[C@H](OC(=O)[C@H]4CC[C@]31C)c5ccoc5)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B10 mock treatment 150760.0 -19300.0 -0.52 192680.0 10900.0 0.29 -0.1575 -0.2649 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B11 compound treatment 153600.0 -16500.0 -0.44 200720.0 18900.0 0.51 0.0501 0.0742 3616506 ACon1_002268 OC1C(O)C2C(C(C1C=C2/C=C/C(=O)O)c3ccc(O)c(O)c3)C(=O)OC(Cc4ccc(O)c(O)c4)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B12 mock treatment 164200.0 -5880.0 -0.16 200160.0 18300.0 0.5 0.2399 0.4605 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B13 mock treatment 172920.0 2840.0 0.08 195440.0 13600.0 0.37 0.3144 0.8352 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B14 mock treatment 171400.0 1320.0 0.04 197840.0 16000.0 0.43 0.3316 0.7621 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B15 compound treatment 175480.0 5400.0 0.14 205120.0 23300.0 0.63 0.5482 0.8471 3558465 ACon1_002269 CC1OC(OC2C(O)C(O)C(CO)OC2Oc3c(oc4cc(OC5OC(C)C(O)C(O)C5O)cc(O)c4c3=O)c6ccc(O)cc6)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B16 mock treatment 180680.0 10600.0 0.28 221400.0 39600.0 1.07 0.9582 0.8644 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B17 compound treatment 171840.0 1760.0 0.05 206400.0 24600.0 0.67 0.5038 0.7552 3555288 ACon1_002270 COc1ccc2CC3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2C54CCN3C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B18 mock treatment 181560.0 11500.0 0.31 203040.0 21200.0 0.57 0.6233 0.9569 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B19 compound treatment 168880.0 -1200.0 -0.03 203880.0 22100.0 0.6 0.3996 0.6681 3559140 ACon1_002271 C/C=C(/C)\C(=O)O[C@H]1CC(C)(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]6O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)[C@@H](O)[C@@H](O)[C@@]12CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B20 mock treatment 208440.0 38400.0 1.03 218120.0 36300.0 0.98 1.4204 0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B21 compound treatment 12720.0 -157000.0 -4.21 15440.0 -166000.0 -4.5 -6.1614 -0.9994 3559603 ACon1_002272 CC1(C)CCCC2C3(C)CCC(C)(CC3CCC21O)C(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B22 mock treatment 215280.0 45200.0 1.21 192160.0 10300.0 0.28 1.0529 0.8484 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B23 compound treatment 213280.0 43200.0 1.16 220080.0 38300.0 1.04 1.5495 0.9985 3558670 ACon1_002273 Oc1ccc2c(cc3NC(=O)c4cc5OCOc5c2c34)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 B24 mock treatment 261040.0 91000.0 2.43 250120.0 68300.0 1.85 3.0279 0.9908 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C01 compound treatment 169480.0 -601.0 -0.02 181240.0 -579.0 -0.02 -0.0225 -0.9999 3557715 ACon1_002274 OC[C@H]1O[C@@H](O[C@H](CCCCc2ccc(O)c(O)c2)CCc3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C02 compound treatment 11680.0 -158000.0 -4.24 14600.0 -167000.0 -4.53 -6.1971 -0.9995 3559945 ACon1_002275 OC[C@H]1O[C@@H](OC(C#N)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C03 compound treatment 158840.0 -11200.0 -0.3 206680.0 24900.0 0.67 0.2633 0.3572 3558659 ACon1_002276 CC(C)(O)c1ccc2c(CCC3C(C)(CCCC32C)C(=O)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C04 compound treatment 158640.0 -11400.0 -0.31 197760.0 15900.0 0.43 0.0888 0.1678 3553732 ACon1_002277 CC(NC(=O)/C=C/C(=O)O)C(=O)NC(C(C)c1c[nH]c2ccccc12)C(=O)NC(Cc3c[nH]c4ccccc34)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C05 compound treatment 64280.0 -106000.0 -2.83 78200.0 -104000.0 -2.81 -3.9847 -1.0 3553321 ACon1_002278 CC(=O)O[C@@H]/1C\C=C(/C)\C[C@@H](OC(=O)/C(=C/CO)/CO)C2[C@H](OC(=O)C2=C)/C=C1/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C06 compound treatment 174720.0 4640.0 0.12 208640.0 26800.0 0.73 0.6012 0.8161 3616509 ACon1_002279 CC1=C[C@H](O)[C@H]2C(C)(C)CCC[C@]2(C)[C@@]1(O)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C07 compound treatment 168800.0 -1280.0 -0.03 222000.0 40200.0 1.09 0.745 0.6845 3554995 ACon1_002280 COc1cc(O)cc2cc3OC(C)(O)CC(=O)c3c(O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C08 compound treatment 47480.0 -123000.0 -3.28 141200.0 -40600.0 -1.1 -3.0965 -0.8952 3554703 ACon1_002281 COC(=O)c1cc(O)cc(O)c1C(=O)c2c(O)cc(C)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C09 compound treatment 157760.0 -12300.0 -0.33 160960.0 -20900.0 -0.56 -0.6324 -0.9671 3559543 ACon1_002282 C[C@]12C[C@H]3OC(=O)C(=C)[C@H]3CC2C(=C)CC[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C10 compound treatment 169520.0 -561.0 -0.02 190840.0 9020.0 0.24 0.1621 0.6624 2107842 ACon1_002283 C[C@H]1C[C@@]2(O)[C@H]([C@H]1OC(=O)c3ccccc3)[C@@H](OC(=O)COC(=O)C)[C@]4(C[C@@H]5[C@H](CC(C)(C)C5=O)[C@](C)(C4OC(=O)C)[C@H]2OC(=O)C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C11 mock treatment 164240.0 -5840.0 -0.16 202840.0 21000.0 0.57 0.2919 0.4947 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C12 mock treatment 157080.0 -13000.0 -0.35 198520.0 16700.0 0.45 0.0738 0.1294 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C13 compound treatment 173080.0 3000.0 0.08 173240.0 -8580.0 -0.23 -0.1075 -0.4375 3554771 ACon1_002284 COc1c(O)ccc2C([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4cc(C)cc(O)c4C(=O)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C14 compound treatment 164920.0 -5160.0 -0.14 192520.0 10700.0 0.29 0.1072 0.3341 3616510 ACon1_002285 CC1CC(=O)C2=C(O1)OC3(C)CCC4(O)C(C)(C)C=CC(=O)C4(C)C3C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C15 mock treatment 155640.0 -14400.0 -0.39 188320.0 6500.0 0.18 -0.1487 -0.3503 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C16 mock treatment 148480.0 -21600.0 -0.58 185240.0 3420.0 0.09 -0.3431 -0.5863 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C17 compound treatment 163160.0 -6920.0 -0.19 198960.0 17100.0 0.46 0.1972 0.3947 3558911 ACon1_002286 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)[C@@H]2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C18 compound treatment 14120.0 -156000.0 -4.17 17640.0 -164000.0 -4.44 -6.0928 -0.9995 3559669 ACon1_002287 COC(=O)C1(C)CCCC(=C)C1CC/C(=C/CCC2=CC(=O)OC2)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C19 compound treatment 168680.0 -1400.0 -0.04 206200.0 24400.0 0.66 0.4402 0.6659 3555826 ACon1_002288 OC(=O)C1OC(=O)C(CCCCCCCCC=C)C1(O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C20 compound treatment 161400.0 -8680.0 -0.23 189000.0 7180.0 0.19 -0.0267 -0.0883 3616511 ACon1_002289 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3C=C(CO)[C@@H]4[C@H]3C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H]2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C21 compound treatment 178840.0 8760.0 0.23 208000.0 26200.0 0.71 0.6669 0.8933 3616514 ACon1_002290 O[C@H]1[C@@H](C[C@@](O)(C[C@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)C(=O)O)OC(=O)/C=C/c3ccc(O)c(O)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C22 compound treatment 167480.0 -2600.0 -0.07 204440.0 22600.0 0.61 0.3838 0.6228 3616517 ACon1_002291 COC(=O)CC1(C/C=C(\C)/CCC=C(C)C)CC(=O)CCC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C23 compound treatment 178720.0 8640.0 0.23 196040.0 14200.0 0.39 0.4356 0.9702 3555607 ACon1_002292 O[C@@H]1Cc2c(O)cc3O[C@]4(Oc5cc(O)cc(O)c5[C@H]([C@H]4O)c3c2O[C@@H]1c6ccc(O)cc6)c7ccc(O)cc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 C24 compound treatment 225840.0 55800.0 1.49 197440.0 15600.0 0.42 1.3537 0.8732 3069520 ACon1_002293 COc1ccc2CC3N(CCc4cc(OC)c(O)cc34)Cc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D01 compound treatment 169400.0 -681.0 -0.02 194120.0 12300.0 0.33 0.2226 0.6674 3616522 ACon1_002294 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3C=C[C@@]56OC[C@@]7(CCC(C)(C)C[C@H]76)[C@@H](O)C[C@]54C)[C@]2(C)CO)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O[C@@H]9O[C@H](CO)[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D02 mock treatment 210040.0 40000.0 1.07 211080.0 29300.0 0.79 1.3159 0.9891 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D03 compound treatment 197960.0 27900.0 0.75 233720.0 51900.0 1.41 1.5209 0.9561 3616525 ACon1_002295 OC[C@H]1O[C@@H](Oc2ccc3[C@@H]4Oc5cc6OCOc6cc5[C@@H]4COc3c2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D04 mock treatment 192640.0 22600.0 0.6 274600.0 92800.0 2.51 2.2028 0.8527 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D05 compound treatment 178240.0 8160.0 0.22 196200.0 14400.0 0.39 0.4296 0.9626 3616527 ACon1_002296 COC(=O)C1=C[C@@H](C[C@H]2[C@]3(C)C[C@H](OC(=O)[C@H]3CC[C@]21C)c4ccoc4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D06 mock treatment 166480.0 -3600.0 -0.1 236360.0 54500.0 1.48 0.976 0.6596 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D07 compound treatment 164800.0 -5280.0 -0.14 203680.0 21900.0 0.59 0.3186 0.5236 3616529 ACon1_002297 CC1OC(OC2C(O)COC(OC3C(O)C(C)OC(OC4C(OC(=O)C56CCC(C)(C)CC6C7=CCC8C9(C)CC(O)C(OC%10OC(C)C(O)C(OC%11OCC(O)C(OC%12OCC(OC%13OCC(O)(CO)C%13O)C(O)C%12O)C%11O)C%10O)C(C)(CO)C9CCC8(C)C7(C)CC5O)OC(C)C(O)C4OC%14OCC(O)C(O)C%14O)C3O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D08 mock treatment 175720.0 5640.0 0.15 222880.0 41100.0 1.11 0.8927 0.7958 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D09 compound treatment 134280.0 -35800.0 -0.96 140720.0 -41100.0 -1.11 -1.4639 -0.9972 3616530 ACon1_002298 CC(C)(O)CCc1cc2[C@@H]3COc4cc(O)ccc4[C@@H]3Oc2cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D10 mock treatment 187720.0 17600.0 0.47 199880.0 18100.0 0.49 0.6794 0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D11 mock treatment 168480.0 -1600.0 -0.04 221520.0 39700.0 1.07 0.7297 0.6784 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D12 mock treatment 165440.0 -4640.0 -0.12 212480.0 30700.0 0.83 0.4992 0.5947 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D13 compound treatment 176960.0 6880.0 0.18 217680.0 35900.0 0.97 0.8166 0.8264 3616533 ACon1_002299 CC1(CO)C(OC2OCC(O)C(O)C2OC3OC(CO)C(O)C(O)C3O)C(O)CC4(C)C1CCC5(C)C4CC=C6C7CC(=C)CCC7(CCC65C)C(=O)OC8OC(CO)C(O)C(O)C8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D14 mock treatment 166320.0 -3760.0 -0.1 231520.0 49700.0 1.35 0.8803 0.6524 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D15 mock treatment 177200.0 7120.0 0.19 208040.0 26200.0 0.71 0.6366 0.8662 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D16 mock treatment 180080.0 10000.0 0.27 222760.0 40900.0 1.11 0.9729 0.8532 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D17 compound treatment 140840.0 -29200.0 -0.78 174400.0 -7420.0 -0.2 -0.6951 -0.8608 3559611 ACon1_002300 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O[C@H]5CC[C@@]6(C)C(CC[C@]7(C)C6CC[C@@]89OC[C@@]%10(CCC(C)(C)CC%109)[C@H](O)C[C@]87C)C5(C)C)O[C@@H]3C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D18 mock treatment 191560.0 21500.0 0.57 196720.0 14900.0 0.4 0.6915 0.985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D19 compound treatment 173640.0 3560.0 0.1 218000.0 36200.0 0.98 0.7599 0.7722 3559413 ACon1_002301 COC(=O)[C@H]1CC[C@H](OC(=O)C)[C@]2(C)CC[C@@H](C(C)C)[C@@H](OC(=O)/C=C/c3ccccc3)C12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D20 mock treatment 156120.0 -14000.0 -0.37 185920.0 4100.0 0.11 -0.1856 -0.4763 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D21 compound treatment 177880.0 7800.0 0.21 183440.0 1620.0 0.04 0.1785 0.8375 3559708 ACon1_002302 CC(OC(=O)/C=C(/C)\COC(=O)C)c1ccc(O)c(c1)C(=O)C=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D22 mock treatment 204760.0 34700.0 0.93 183120.0 1300.0 0.04 0.6808 0.7334 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D23 compound treatment 178000.0 7920.0 0.21 153120.0 -28700.0 -0.78 -0.3996 -0.4962 3558805 ACon1_002303 CC1[C@@H]2CCC3(C)OC43C(O)C=C(C)C4[C@H]2OC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 D24 mock treatment 193440.0 23400.0 0.62 184920.0 3100.0 0.08 0.5012 0.795 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E01 mock treatment 171640.0 1560.0 0.04 174600.0 -7220.0 -0.2 -0.1087 -0.544 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E02 mock treatment 150360.0 -19700.0 -0.53 199520.0 17700.0 0.48 -0.0342 -0.0479 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E03 compound treatment 13360.0 -157000.0 -4.19 14960.0 -167000.0 -4.52 -6.1585 -0.9993 3616539 ACon1_002304 COc1cccc2C(=O)c3c(C(=O)c12)c(O)cc4CC(C)(O)CC(=O)c43 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E04 compound treatment 148520.0 -21600.0 -0.58 186880.0 5060.0 0.14 -0.3109 -0.5245 3616542 ACon1_002305 CC(O)/C=C/C1(O)C(C)CC(O)CC1(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E05 compound treatment 176880.0 6800.0 0.18 196560.0 14700.0 0.4 0.4108 0.9367 1054502 ACon1_002306 COc1cc2n(C)c3ccccc3c(=O)c2c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E06 compound treatment 156320.0 -13800.0 -0.37 241440.0 59600.0 1.61 0.8811 0.5322 3616546 ACon1_002307 CC1OC(OCC2(C)CCC3(CCC4(C)C(CCC5C6(C)CCC(O)C(C)(COC7OC(CO)C(O)C(O)C7O)C6CCC54C)C3=C2)C(=O)O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E07 compound treatment 156560.0 -13500.0 -0.36 177200.0 -4620.0 -0.13 -0.3442 -0.8993 3616548 ACon1_002308 CC(O)CC1CCC(O)C(C)C(=O)OC(CC(C)O)CCC(O)C(C)C(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E08 compound treatment 170880.0 799.0 0.02 196680.0 14900.0 0.4 0.2996 0.7436 3559871 ACon1_002309 C/C=C\1/CN2C3Cc4c([nH]c5ccc(O)cc45)C2(O)CC1C3CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E09 mock treatment 154520.0 -15600.0 -0.42 177360.0 -4460.0 -0.12 -0.3797 -0.8761 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E10 mock treatment 149360.0 -20700.0 -0.55 201200.0 19400.0 0.52 -0.0209 -0.0274 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E11 compound treatment 177880.0 7800.0 0.21 190480.0 8660.0 0.23 0.3133 0.9983 3559551 ACon1_002310 C[C@H]1C[C@H]2OC(=O)C(=C2CC/C(=C/CC1=O)/C)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E12 compound treatment 147040.0 -23000.0 -0.62 172360.0 -9460.0 -0.26 -0.6169 -0.9243 3616552 ACon1_002311 CC1CCC2C(=CC3(O)CC(C)(C)CC123)C(=O)OC4OC(C)C(O)C(O)C4O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E13 compound treatment 98240.0 -71800.0 -1.92 107280.0 -74500.0 -2.02 -2.7857 -0.9997 3420076 ACon1_002312 CC1CC(C)C(=O)C(C1)C(O)CC2CC(=O)NC(=O)C2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E14 compound treatment 14800.0 -155000.0 -4.15 18280.0 -164000.0 -4.43 -6.0677 -0.9995 3559755 ACon1_002313 CC1(CCCC(C)(C)C2C3CCC21)C3CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E15 compound treatment 171600.0 1520.0 0.04 169560.0 -12300.0 -0.33 -0.2059 -0.616 3554678 ACon1_002314 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/[C@@H]1CC(=O)OC[C@H]3O[C@@H](OCCc4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]3OC(=O)C[C@H]5\C(=C\C)\[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)OC=C5C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E16 compound treatment 173520.0 3440.0 0.09 198680.0 16900.0 0.46 0.3878 0.8328 3559326 ACon1_002315 CC(=CCC/C(=C/CC(O)/C(=C/Cc1cc(ccc1O)C(=O)O)/C)/C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E17 mock treatment 146360.0 -23700.0 -0.63 188760.0 6940.0 0.19 -0.3158 -0.4772 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E18 mock treatment 162600.0 -7480.0 -0.2 182720.0 901.0 0.02 -0.1243 -0.6163 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E19 compound treatment 169760.0 -321.0 -0.01 189080.0 7260.0 0.2 0.1329 0.6755 3553717 ACon1_002316 CC(CCCCC(O)C(CO)C(=O)OC(CCCCC(C)C/C(=C/C(=C/C(=O)O)/C)/C)C(CO)C(=O)O)C/C(=C/C(=C/C(=O)O)/C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E20 compound treatment 163200.0 -6880.0 -0.18 183760.0 1940.0 0.05 -0.093 -0.4858 3616556 ACon1_002317 O=C(NCCCCNCCCNC(=O)/C=C/c1ccccc1)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E21 compound treatment 172200.0 2120.0 0.06 186160.0 4340.0 0.12 0.1232 0.9441 3554770 ACon1_002318 COc1c(O)cc2C(Oc3cc4C(O)C(C)OC(=O)c4c(O)c3OC)C(C)OC(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E22 compound treatment 165040.0 -5040.0 -0.13 209400.0 27600.0 0.75 0.4326 0.5702 3616560 ACon1_002319 O[C@@H]1[C@@H](COC(=O)/C=C/C2(O)C=CC(=O)C=C2)O[C@@H](Oc3ccc(O)cc3)[C@H](O)[C@H]1OC(=O)/C=C/C4(O)C=CC(=O)C=C4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E23 compound treatment 121160.0 -48900.0 -1.31 113600.0 -68200.0 -1.85 -2.2312 -0.9858 1088382 ACon1_002320 CCC(C)C1NC(=O)C2CCCN2C(=O)C(CC(C)C)OC(=O)CCNC(=O)C(C)N(C)C(=O)C(C(C)C)N(C)C1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 E24 compound treatment 20760.0 -149000.0 -3.99 20160.0 -162000.0 -4.38 -5.919 -0.999 3616565 ACon1_002321 OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F01 mock treatment 177600.0 7520.0 0.2 200880.0 19100.0 0.52 0.5071 0.9156 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F02 mock treatment 184880.0 14800.0 0.4 182720.0 901.0 0.02 0.2972 0.7493 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F03 compound treatment 156280.0 -13800.0 -0.37 178040.0 -3780.0 -0.1 -0.3334 -0.8703 3212153 ACon1_002322 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F04 mock treatment 154720.0 -15400.0 -0.41 224920.0 43100.0 1.17 0.5345 0.4321 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F05 compound treatment 159360.0 -10700.0 -0.29 172080.0 -9740.0 -0.26 -0.3892 -0.9991 3616570 ACon1_002323 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H]4CN5CCc6c([nH]c7ccccc67)[C@]5(C[C@@H]31)O4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F06 mock treatment 148760.0 -21300.0 -0.57 215960.0 34100.0 0.92 0.2503 0.2305 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F07 compound treatment 157840.0 -12200.0 -0.33 171000.0 -10800.0 -0.29 -0.4386 -0.9985 3616572 ACon1_002324 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](COC3OCC(O)C(O)C3O)O[C@@H](Oc4cc(O)c5C(=O)CC(Oc5c4)c6ccc(O)cc6)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F08 mock treatment 157600.0 -12500.0 -0.33 175480.0 -6340.0 -0.17 -0.3574 -0.9521 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F09 mock treatment 157680.0 -12400.0 -0.33 177800.0 -4020.0 -0.11 -0.3115 -0.8923 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F10 mock treatment 174920.0 4840.0 0.13 176000.0 -5820.0 -0.16 -0.0199 -0.0975 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F11 compound treatment 168360.0 -1720.0 -0.05 160880.0 -20900.0 -0.57 -0.4334 -0.762 3616576 ACon1_002325 CC(=CCc1cc2C(=O)C(O)C(Oc2c3C(O)C(O)C(C)(C)Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F12 mock treatment 156640.0 -13400.0 -0.36 194320.0 12500.0 0.34 -0.0149 -0.0302 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F13 compound treatment 178320.0 8240.0 0.22 205680.0 23900.0 0.65 0.6126 0.8975 3616580 ACon1_002326 COc1cc(CC2COC(C2COC3OC(CO)C(O)C(O)C3O)c4ccc(O)c(OC)c4)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F14 mock treatment 148440.0 -21600.0 -0.58 195320.0 13500.0 0.37 -0.1509 -0.2204 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F15 compound treatment 156960.0 -13100.0 -0.35 184400.0 2580.0 0.07 -0.1988 -0.5554 2090754 ACon1_002327 COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F16 mock treatment 161640.0 -8440.0 -0.23 164760.0 -17100.0 -0.46 -0.4862 -0.9458 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F17 mock treatment 145880.0 -24200.0 -0.65 175120.0 -6700.0 -0.18 -0.586 -0.8716 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F18 mock treatment 170120.0 38.6 0.0 178320.0 -3500.0 -0.09 -0.0662 -0.6994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F19 compound treatment 159640.0 -10400.0 -0.28 193160.0 11300.0 0.31 0.0196 0.0473 3559435 ACon1_002328 COc1c2occc2c(OCC(OC(=O)/C(=C\C)/C)C(C)(C)O)c3ccc(=O)oc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F20 mock treatment 152480.0 -17600.0 -0.47 172720.0 -9100.0 -0.25 -0.5071 -0.9543 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F21 compound treatment 166280.0 -3800.0 -0.1 192760.0 10900.0 0.3 0.1375 0.4392 3558554 ACon1_002329 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@H]7OC[C@](O)(CO)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F22 mock treatment 154920.0 -15200.0 -0.41 194480.0 12700.0 0.34 -0.0444 -0.0836 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F23 compound treatment 163640.0 -6440.0 -0.17 171840.0 -9980.0 -0.27 -0.3129 -0.9764 3616583 ACon1_002330 OC(=O)c1cc(O)c(O)c(O)c1Oc2cc3C(=O)OC[C@H]4O[C@@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@H](OC(=O)c6cc(O)c(O)c(O)c6)[C@@H](OC(=O)c7cc(O)c(O)c(O)c7)[C@@H]4OC(=O)c8cc(O)c(O)c(O)c8-c3c(O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 F24 mock treatment 167200.0 -2880.0 -0.08 190680.0 8860.0 0.24 0.1151 0.4569 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G01 compound treatment 167920.0 -2160.0 -0.06 223160.0 41300.0 1.12 0.7505 0.6697 3557489 ACon1_002331 CC12CC3(CC2C1CC34)CC(O)C5C(C)(CO)CCCC45C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G02 compound treatment 187840.0 17800.0 0.48 217680.0 35900.0 0.97 1.0224 0.9459 3557405 ACon1_002332 CCCC(O)C(O)C1CC(=CC(=O)O1)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G03 mock treatment 180520.0 10400.0 0.28 175120.0 -6700.0 -0.18 0.0692 0.2078 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G04 mock treatment 158880.0 -11200.0 -0.3 214280.0 32500.0 0.88 0.4095 0.4411 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G05 compound treatment 164720.0 -5360.0 -0.14 166400.0 -15400.0 -0.42 -0.3966 -0.8985 3554767 ACon1_002333 COc1c(O)c2c(CCC3C(C)(C)CCC[C@@]32C(=O)O)cc1C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G06 compound treatment 171400.0 1320.0 0.04 178760.0 -3060.0 -0.08 -0.0336 -0.3735 3616588 ACon1_002334 COC(=O)c1cc(C)cc(O)c1C(=O)c2c(O)cccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G07 compound treatment 159680.0 -10400.0 -0.28 179120.0 -2700.0 -0.07 -0.2484 -0.8635 1034509 ACon1_002335 Cc1cc(=O)c2COc3cc(O)c(O)c(C(=O)O)c3-c2o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G08 compound treatment 124160.0 -45900.0 -1.23 133560.0 -48300.0 -1.31 -1.7924 -0.9995 3552648 ACon1_002336 C[C@@H]1C[C@H](O)/C=C/[C@H](O)[C@@H](O)CC(=O)O1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G09 compound treatment 165960.0 -4120.0 -0.11 168480.0 -13300.0 -0.36 -0.3333 -0.8828 3557256 ACon1_002337 CC(=O)c1c(O)cc(O)cc1CC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G10 compound treatment 25120.0 -145000.0 -3.88 26320.0 -155000.0 -4.21 -5.7186 -0.9992 3555790 ACon1_002338 O=C1NC(Cc2c[nH]c3ccccc23)C(=O)N4CCCC41 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G11 compound treatment 152480.0 -17600.0 -0.47 165000.0 -16800.0 -0.46 -0.6549 -0.9999 3616592 ACon1_002339 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(CO)CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G12 compound treatment 193160.0 23100.0 0.62 197440.0 15600.0 0.42 0.7356 0.983 3616597 ACon1_002340 CCCC1(O)Cc2c(O1)c3c(O)cccc3cc2C(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G13 compound treatment 183480.0 13400.0 0.36 185320.0 3500.0 0.09 0.3204 0.8644 3558181 ACon1_002341 COc1cc(ccc1O)C2OCC3C(OC(=O)C23)c4ccc5OCOc5c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G14 compound treatment 181760.0 11700.0 0.31 181240.0 -579.0 -0.02 0.2098 0.6708 1029487 ACon1_002342 OCC(O)Cc1ccc2OCOc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G15 compound treatment 156880.0 -13200.0 -0.35 181040.0 -779.0 -0.02 -0.2646 -0.748 3553721 ACon1_002343 CC(CCCCCC(O)C(CO)C(=O)O)C/C(=C/C(=C/C(=O)O)/C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G16 compound treatment 174600.0 4520.0 0.12 195080.0 13300.0 0.36 0.3393 0.8958 3554667 ACon1_002344 COC(=O)C1(CO)C2Cc3c(C4CC1/C(=C\C)/CN42)n(C)c5ccccc35 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G17 compound treatment 148560.0 -21500.0 -0.58 167440.0 -14400.0 -0.39 -0.6823 -0.9818 3558054 ACon1_002345 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\CO)/[C@@H]1CC(=O)OCCc3ccc(O)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G18 compound treatment 162800.0 -7280.0 -0.19 176720.0 -5100.0 -0.14 -0.2353 -0.9858 3553083 ACon1_002346 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5CC(CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)N9C[C@@H](C)CC[C@H]19 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G19 mock treatment 181720.0 11600.0 0.31 167200.0 -14600.0 -0.4 -0.0597 -0.1186 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G20 mock treatment 155320.0 -14800.0 -0.39 197320.0 15500.0 0.42 0.0175 0.0304 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G21 compound treatment 190800.0 20700.0 0.55 193360.0 11500.0 0.31 0.6128 0.9632 3557521 ACon1_002347 COc1cc(/C=C/C(=O)OC2C(O)C(O)C(OC3(CO)OC(CO)C(O)C3O)OC2COC(=O)c4cc(OC)c(OC)c(OC)c4)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G22 compound treatment 159320.0 -10800.0 -0.29 167720.0 -14100.0 -0.38 -0.4734 -0.9903 3557725 ACon1_002348 OC[C@H]1OC(Oc2cc(O)c3c(=O)c(O)c(oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G23 compound treatment 186960.0 16900.0 0.45 189560.0 7740.0 0.21 0.4674 0.9391 3558206 ACon1_002349 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]1OC(=O)/C=C/c6ccc(O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 G24 compound treatment 208720.0 38600.0 1.03 205200.0 23400.0 0.63 1.1784 0.9723 1011276 ACon1_002350 COc1ccc2CC3N(C)CCc4cc5OCOc5c(c34)-c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H01 compound treatment 175240.0 5160.0 0.14 207840.0 26000.0 0.7 0.5957 0.8298 3616603 ACon1_002351 O[C@H]1[C@H](O)[C@@H](COC(=O)CC(=O)O)O[C@@H](Oc2ccc3[C@@H]4Oc5cc6OCOc6cc5[C@@H]4COc3c2)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H02 mock treatment 192640.0 22600.0 0.6 233560.0 51700.0 1.4 1.4172 0.9292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H03 mock treatment 181640.0 11600.0 0.31 187720.0 5900.0 0.16 0.3316 0.9528 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H04 mock treatment 180120.0 10000.0 0.27 238720.0 56900.0 1.54 1.2791 0.818 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H05 compound treatment 208680.0 38600.0 1.03 228760.0 46900.0 1.27 1.6287 0.9947 3616608 ACon1_002352 COC(=O)C1=CC(=C[C@H]2[C@]3(C)C[C@H](OC(=O)[C@H]3CC[C@]21C)c4ccoc4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H06 mock treatment 188880.0 18800.0 0.5 231080.0 49300.0 1.33 1.2986 0.9111 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H07 compound treatment 163560.0 -6520.0 -0.17 214000.0 32200.0 0.87 0.4927 0.5545 3616611 ACon1_002353 CC(C)(CCO[C@@H]1O[C@H](CO[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)C[C@@H]3C(=CC[C@]4(C(=O)O)C3=CCC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)C6CC[C@]54C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H08 mock treatment 194280.0 24200.0 0.65 199320.0 17500.0 0.47 0.7927 0.9882 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H09 compound treatment 173440.0 3360.0 0.09 209600.0 27800.0 0.75 0.5953 0.786 3616613 ACon1_002354 Oc1ccccc1Cc2c(O)cc(O)c3C(=O)C[C@@H](Oc23)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H10 mock treatment 196440.0 26400.0 0.71 184360.0 2540.0 0.07 0.5472 0.7724 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H11 compound treatment 186440.0 16400.0 0.44 191760.0 9940.0 0.27 0.4997 0.9728 3558021 ACon1_002355 OCC1OC(C(O)C(O)C1O)c2c(O)cc(O)c3c(=O)cc(oc23)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H12 mock treatment 196480.0 26400.0 0.71 203560.0 21700.0 0.59 0.9155 0.9959 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H13 compound treatment 190040.0 20000.0 0.53 201920.0 20100.0 0.54 0.7623 1.0 3616618 ACon1_002356 CC(O)CCCc1cc(O)cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H14 mock treatment 177960.0 7880.0 0.21 204000.0 22200.0 0.6 0.5736 0.9014 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H15 compound treatment 202600.0 32500.0 0.87 174720.0 -7100.0 -0.19 0.4792 0.5379 3616621 ACon1_002357 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H16 mock treatment 162400.0 -7680.0 -0.21 197880.0 16100.0 0.43 0.1622 0.3372 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H17 compound treatment 25120.0 -145000.0 -3.88 37440.0 -144000.0 -3.91 -5.5057 -1.0 3559631 ACon1_002358 COc1ccc(OC)c(/C=C/C(=O)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H18 mock treatment 187600.0 17500.0 0.47 172880.0 -8940.0 -0.24 0.1602 0.3038 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H19 mock treatment 196520.0 26400.0 0.71 185760.0 3940.0 0.11 0.5755 0.8047 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H20 mock treatment 163520.0 -6560.0 -0.18 187160.0 5340.0 0.14 -0.0219 -0.0961 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H21 compound treatment 194960.0 24900.0 0.67 197440.0 15600.0 0.42 0.7696 0.9761 3559126 ACon1_002359 CO[C@]1(OC[C@@H]2[C@H](OC[C@@]21O)c3ccc4OCOc4c3)c5ccc6OCOc6c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H22 mock treatment 196320.0 26200.0 0.7 197480.0 15700.0 0.42 0.7961 0.9709 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H23 compound treatment 188240.0 18200.0 0.49 220280.0 38500.0 1.04 1.0797 0.9397 3558476 ACon1_002360 COc1cc(C[C@@H]2CO[C@H]([C@@H]2CO)c3ccc(O)c(OC)c3)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 H24 mock treatment 200680.0 30600.0 0.82 175920.0 -5900.0 -0.16 0.4658 0.5586 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I01 compound treatment 161560.0 -8520.0 -0.23 164480.0 -17300.0 -0.47 -0.4931 -0.945 1086162 ACon1_002361 COc1c2ccoc2c(OC)c3oc(=O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I02 compound treatment 172200.0 2120.0 0.06 209240.0 27400.0 0.74 0.565 0.7589 3557472 ACon1_002362 COC1=CC(=O)CC(C)C21Oc3cc(OC)cc(O)c3C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I03 compound treatment 158640.0 -11400.0 -0.31 173520.0 -8300.0 -0.22 -0.3753 -0.9884 3553181 ACon1_002363 CC(=C1CC[C@@]2(CO[C@@H]3C2)C1CC[C@]3(O)C(=O)O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I04 compound treatment 22280.0 -148000.0 -3.95 18600.0 -163000.0 -4.42 -5.9201 -0.9985 3616624 ACon1_002364 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(NC(=O)C(C)NC(=O)/C=C/C(=O)O)C(C)c3c[nH]c4ccccc34 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I05 mock treatment 155000.0 -15100.0 -0.4 168800.0 -13000.0 -0.35 -0.5345 -0.9977 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I06 mock treatment 171360.0 1280.0 0.03 199960.0 18100.0 0.49 0.3715 0.7545 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I07 compound treatment 157160.0 -12900.0 -0.35 174800.0 -7020.0 -0.19 -0.3788 -0.9603 3616627 ACon1_002365 C[C@H]1[C@H](O)CCC2=C[C@@H](O)[C@@]3(O[C@@H]3[C@]12C)C(=C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I08 compound treatment 156280.0 -13800.0 -0.37 194280.0 12500.0 0.34 -0.0225 -0.045 3557433 ACon1_002366 C[C@]1([C@H](O)CC(=O)c2coc3C(=O)c4c5CCC(=O)c5ccc41)c23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I09 compound treatment 161440.0 -8640.0 -0.23 204720.0 22900.0 0.62 0.275 0.4155 3554518 ACon1_002367 CO[C@H]1C(=O)Nc2ccc(CC=C(C)C)c(O)c2[C@]1(O)c3ccc(OC)cc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I10 compound treatment 169880.0 -201.0 -0.01 195800.0 14000.0 0.38 0.2638 0.697 3616630 ACon1_002368 COc1cc2oc(C)cc(=O)c2c(O)c1CSCC(O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I11 compound treatment 152040.0 -18000.0 -0.48 182640.0 821.0 0.02 -0.3255 -0.6738 3558142 ACon1_002369 OC[C@H]1O[C@@H](O[C@H]2C[C@@H]3[C@@H]([C@H]4OC(=O)C(=C)[C@@H]4[C@H](O)CC3=C)C2=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I12 compound treatment 29320.0 -141000.0 -3.77 24960.0 -157000.0 -4.25 -5.6652 -0.9982 3616631 ACon1_002370 C/C=C/CCCCC(=O)C(C)C(=O)N1CCC=C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I13 compound treatment 178120.0 8040.0 0.22 171680.0 -10100.0 -0.27 -0.042 -0.1206 3554843 ACon1_002371 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4OC(=O)C)c2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I14 compound treatment 164800.0 -5280.0 -0.14 158480.0 -23300.0 -0.63 -0.5467 -0.8444 1403 ACon1_002372 COC(=O)C1=CCCN(C)C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I15 compound treatment 187120.0 17000.0 0.46 215360.0 33500.0 0.91 0.9644 0.9492 3552057 ACon1_002373 C/C=C/C(O)C(C)CC(C)C(OC(=O)CCC(=O)O)C(C)/C=C/C=C/C=C(\C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I16 compound treatment 164000.0 -6080.0 -0.16 189040.0 7220.0 0.2 0.0232 0.0913 3554656 ACon1_002374 COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(=C32)C)c4ccoc4)[C@H](OC(=O)C)C5[C@@](C)(C=CC(=O)[C@]15C)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I17 compound treatment 186040.0 16000.0 0.43 196640.0 14800.0 0.4 0.5856 0.9995 3551981 ACon1_002375 C/C(=C\CCC1(C)C2CCC(C2)C1(C)O)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I18 compound treatment 16040.0 -154000.0 -4.12 16520.0 -165000.0 -4.48 -6.0779 -0.9991 3616633 ACon1_002376 COc1cc(cc2OCOc21)C3OCC4C(OCC34)c5ccc(OC)c(OC)c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I19 compound treatment 176160.0 6080.0 0.16 201720.0 19900.0 0.54 0.4959 0.8812 3559399 ACon1_002377 OC[C@H]1O[C@@H](O[C@H](C#N)c2ccccc2)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I20 compound treatment 156200.0 -13900.0 -0.37 221440.0 39600.0 1.07 0.4959 0.4369 3616634 ACon1_002378 CC(CC(C)OC(=O)/C=C/c1ccc(O)cc1)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I21 mock treatment 153600.0 -16500.0 -0.44 163040.0 -18800.0 -0.51 -0.6712 -0.9975 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I22 mock treatment 149120.0 -21000.0 -0.56 182800.0 981.0 0.03 -0.3777 -0.6729 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I23 compound treatment 173000.0 2920.0 0.08 173120.0 -8700.0 -0.24 -0.1113 -0.4487 3559277 ACon1_002379 CC(=O)C12CC(CCC2(C)CCC1O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 I24 compound treatment 174000.0 3920.0 0.1 209720.0 27900.0 0.76 0.6082 0.7976 3616636 ACon1_002380 OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](OC(=O)/C=C/C3(O)C=CC(=O)C=C3)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J01 compound treatment 183120.0 13000.0 0.35 173520.0 -8300.0 -0.22 0.0877 0.2115 3616638 ACon1_002381 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCC3(C)Oc4cc5occ(c6ccc(O)cc6)c(=O)c5c(O)c4C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J02 mock treatment 155880.0 -14200.0 -0.38 177560.0 -4260.0 -0.12 -0.3501 -0.882 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J03 compound treatment 160640.0 -9440.0 -0.25 189040.0 7220.0 0.2 -0.0403 -0.1263 3616640 ACon1_002382 CC(=CCc1c(O)c(CC=C(C)C)c2OC(CC(=O)c2c1O)c3ccccc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J04 mock treatment 155760.0 -14300.0 -0.38 206560.0 24700.0 0.67 0.2027 0.2628 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J05 mock treatment 167440.0 -2640.0 -0.07 183960.0 2140.0 0.06 -0.009 -0.0982 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J06 mock treatment 173600.0 3520.0 0.09 176560.0 -5260.0 -0.14 -0.0341 -0.1999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J07 compound treatment 33080.0 -137000.0 -3.66 27240.0 -155000.0 -4.18 -5.5504 -0.9978 3616641 ACon1_002383 CC1(CO)C(CCC2(C)C1CCC3(C)C2CC=C4C5CC(=C)CCC5(CCC43C)C(=O)OC6OC(CO)C(O)C(O)C6OC7OCC(O)C(O)C7O)OC8OC(CO)C(O)C(O)C8O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J08 mock treatment 154480.0 -15600.0 -0.42 159120.0 -22700.0 -0.61 -0.7296 -0.9822 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J09 compound treatment 135480.0 -34600.0 -0.93 135480.0 -46300.0 -1.25 -1.5415 -0.9888 3616643 ACon1_002384 COc1cc(cc2CC(Oc21)C(=C)C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J10 mock treatment 153320.0 -16800.0 -0.45 195800.0 14000.0 0.38 -0.0494 -0.0842 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J11 compound treatment 181600.0 11500.0 0.31 175880.0 -5940.0 -0.16 0.1042 0.2998 3616644 ACon1_002385 CC(=CCc1cc2[C@@H]3COc4c(O)c(O)ccc4[C@@H]3Oc2cc1O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J12 mock treatment 163320.0 -6760.0 -0.18 176440.0 -5380.0 -0.15 -0.2309 -0.9942 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J13 compound treatment 166160.0 -3920.0 -0.1 152760.0 -29100.0 -0.79 -0.6304 -0.7944 3616646 ACon1_002386 O[C@@H]1[C@@H](O)[C@H](Oc2ccc(cc2)c3coc4cc(O)ccc4c3=O)O[C@@H]([C@H]1O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J14 mock treatment 151440.0 -18600.0 -0.5 164880.0 -16900.0 -0.46 -0.6769 -0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J15 compound treatment 177480.0 7400.0 0.2 189000.0 7180.0 0.19 0.2774 1.0 3616648 ACon1_002387 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)CO[C@@H](O[C@H]3[C@H](C)O[C@@H](O[C@@H]4[C@@H](O)[C@H](CO)O[C@H]4OC(=O)[C@@]56CCC(C)(C)C[C@H]6C7=CCC8[C@@]9(C)C[C@H](O)[C@H](O[C@@H]%10O[C@@H]([C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@@](C)(CO)C9[C@H](O)C[C@@]8(C)[C@]7(C)C[C@H]5O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J16 mock treatment 163360.0 -6720.0 -0.18 159960.0 -21900.0 -0.59 -0.5456 -0.8821 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J17 compound treatment 156520.0 -13600.0 -0.36 174400.0 -7420.0 -0.2 -0.3985 -0.9611 3557669 ACon1_002388 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@H](O)C[C@@H](O)[C@]5(C)C4CC[C@]23C)O[C@]61OCC(=C)[C@H](O)[C@@H]6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J18 mock treatment 151960.0 -18100.0 -0.48 169600.0 -12200.0 -0.33 -0.5767 -0.9826 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J19 compound treatment 188440.0 18400.0 0.49 176560.0 -5260.0 -0.14 0.2466 0.4822 3559791 ACon1_002389 COc1ccc(cc1)C(=O)O[C@H]2CC(=CC[C@@]3(C)[C@@H](O)C[C@@](O)(C(C)C)[C@H]23)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J20 mock treatment 156720.0 -13400.0 -0.36 166960.0 -14900.0 -0.4 -0.5372 -0.9983 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J21 mock treatment 183800.0 13700.0 0.37 156160.0 -25700.0 -0.69 -0.2317 -0.2949 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J22 mock treatment 143240.0 -26800.0 -0.72 157960.0 -23900.0 -0.65 -0.9644 -0.9986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J23 mock treatment 166320.0 -3760.0 -0.1 178920.0 -2900.0 -0.08 -0.1266 -0.9924 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 J24 mock treatment 163680.0 -6400.0 -0.17 174640.0 -7180.0 -0.19 -0.2585 -0.998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K01 compound treatment 165160.0 -4920.0 -0.13 156960.0 -24900.0 -0.67 -0.569 -0.8297 3554199 ACon1_002390 CCc1c(O)cc(O)c2C(=O)C[C@@H](C)Oc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K02 compound treatment 165480.0 -4600.0 -0.12 190120.0 8300.0 0.22 0.0719 0.2805 3559924 ACon1_002391 CC1CCC(=C)/C(=C\C=C/CC1(C)CCC2=CC(=O)OC2O)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K03 compound treatment 195160.0 25100.0 0.67 176640.0 -5180.0 -0.14 0.3752 0.5475 3558269 ACon1_002392 C[C@@]1(O)CCC[C@]2(C)CC[C@H](C[C@@H]12)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K04 compound treatment 89640.0 -80400.0 -2.15 33160.0 -149000.0 -4.02 -4.3673 -0.957 3559641 ACon1_002393 O/C(=C\C(=O)/C=C/c1ccccc1)/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K05 compound treatment 156920.0 -13200.0 -0.35 168440.0 -13400.0 -0.36 -0.5051 -0.9999 3554959 ACon1_002394 COc1cc(O)c(C(=O)C)c(CC(=O)O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K06 compound treatment 157600.0 -12500.0 -0.33 171000.0 -10800.0 -0.29 -0.4432 -0.9979 3616650 ACon1_002395 COc1cc(oc(=O)c1C)/C(=C/C(C)O)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K07 mock treatment 160040.0 -10000.0 -0.27 160800.0 -21000.0 -0.57 -0.5923 -0.9413 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K08 mock treatment 180560.0 10500.0 0.28 176080.0 -5740.0 -0.16 0.0883 0.2756 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K09 compound treatment 137480.0 -32600.0 -0.87 149120.0 -32700.0 -0.89 -1.2426 -1.0 3559867 ACon1_002396 COc1c(O)cc2CCNC3Cc4ccccc4-c1c32 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K10 compound treatment 13320.0 -157000.0 -4.19 12520.0 -169000.0 -4.58 -6.2059 -0.999 3616653 ACon1_002397 CC(CCO)/C=C(/C)\C=C\C1=CC2=CC(=O)C(C)(O)C(O)C2=CO1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K11 compound treatment 12640.0 -157000.0 -4.21 13120.0 -169000.0 -4.57 -6.2073 -0.9992 3558744 ACon1_002398 COc1cc(/C=C/CO)cc(OC)c1OC\C=C(/C)\CCC=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K12 compound treatment 169000.0 -1080.0 -0.03 189320.0 7500.0 0.2 0.1231 0.6003 3616654 ACon1_002399 CC1CCCC[C@@H]2[C@@H](CC(=O)O1)[C@@H](O)C=CC2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K13 compound treatment 170000.0 -81.4 0.0 169480.0 -12300.0 -0.33 -0.2377 -0.7117 3557992 ACon1_002400 C[C@@H]1C[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@]2(COC(=O)C)[C@@H](C[C@@H]3[C@@H](OC(=O)C)[C@]12OC3(C)C)OC(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K14 compound treatment 15960.0 -154000.0 -4.12 15440.0 -166000.0 -4.5 -6.1001 -0.999 2732 ACon1_002401 Cc1cc(=O)oc2cc(O)ccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K15 mock treatment 163080.0 -7000.0 -0.19 171680.0 -10100.0 -0.27 -0.3265 -0.9826 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K16 mock treatment 175080.0 5000.0 0.13 141160.0 -40700.0 -1.1 -0.6838 -0.6167 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K17 compound treatment 171000.0 919.0 0.02 197800.0 16000.0 0.43 0.3233 0.7461 3554976 ACon1_002402 COc1cc(O)c(Oc2cc(C)cc(O)c2C(=O)O)c(CO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K18 compound treatment 151800.0 -18300.0 -0.49 172320.0 -9500.0 -0.26 -0.5276 -0.955 3616656 ACon1_002403 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)OC(=O)C)OC(=O)/C=C/c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K19 compound treatment 172240.0 2160.0 0.06 193080.0 11300.0 0.3 0.2564 0.8263 3559928 ACon1_002404 COC1OC(=O)C(=C1)CCC2(C)C/C=C\C=C(\C(=O)O)/C(=C)CCC2C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K20 compound treatment 57760.0 -112000.0 -3.0 41480.0 -140000.0 -3.8 -4.811 -0.9932 3558737 ACon1_002405 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K21 compound treatment 96280.0 -73800.0 -1.97 108560.0 -73300.0 -1.98 -2.7983 -1.0 3557421 ACon1_002406 Cc1cc(O)cc(Oc2cc(C)cc(O)c2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K22 compound treatment 11880.0 -158000.0 -4.23 12800.0 -169000.0 -4.58 -6.2278 -0.9992 3616657 ACon1_002407 CC1CCC2(CCC3(C(=O)O)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C)C(=O)OC6OC(CO)C(O)C(O)C6O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K23 mock treatment 152160.0 -17900.0 -0.48 175000.0 -6820.0 -0.18 -0.4695 -0.914 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 K24 mock treatment 172680.0 2600.0 0.07 187880.0 6060.0 0.16 0.1652 0.9269 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L01 compound treatment 185120.0 15000.0 0.4 167720.0 -14100.0 -0.38 0.0145 0.0262 3616659 ACon1_002408 C/C(=C\CCC(=C)C1(O)CCC(=CC1)C)/C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L02 mock treatment 159800.0 -10300.0 -0.28 195440.0 13600.0 0.37 0.0663 0.1441 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L03 compound treatment 75040.0 -95000.0 -2.54 38760.0 -143000.0 -3.87 -4.5362 -0.9792 3616661 ACon1_002409 OC(=O)C(Cc1ccc(O)c(O)c1)OC(=O)/C=C/c2ccc3O[C@@H]([C@@H](Oc3c2)C(=O)O)c4ccc(O)c(O)c4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L04 mock treatment 183160.0 13100.0 0.35 181720.0 -98.9 0.0 0.2455 0.7017 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L05 compound treatment 167720.0 -2360.0 -0.06 187080.0 5260.0 0.14 0.0561 0.3597 3616663 ACon1_002410 COC(=O)C1CC(=O)C[C@@H]2[C@@]1(C)CC[C@@H]3C(=O)O[C@@H](C[C@]32C)c4ccoc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L06 mock treatment 171360.0 1280.0 0.03 174400.0 -7420.0 -0.2 -0.1178 -0.5784 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L07 mock treatment 167040.0 -3040.0 -0.08 156840.0 -25000.0 -0.68 -0.5357 -0.7865 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L08 mock treatment 173200.0 3120.0 0.08 149160.0 -32700.0 -0.88 -0.5662 -0.6376 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L09 compound treatment 167080.0 -3000.0 -0.08 149320.0 -32500.0 -0.88 -0.6789 -0.7684 3616665 ACon1_002411 C/C(=C\CCC(C)(OC1OCC(O)C(O)C1OC(=O)\C(=C\CCC(C)(O)C=C)\C)C=C)/C(=O)OC2CC3(C(O)CC4(C)C(=CCC5C6(C)CCC(OC7OC(CO)C(OC8OC(CO)C(O)C(OC9OCC(O)C(O)C9O)C8O)C(O)C7O)C(C)(C)C6CCC54C)C3CC2(C)C)C(=O)OC%10OCC(OC%11OC(CO)C(O)C(OC%12OC(CO)C(OC%13OC(CO)C(O)C(O)C%13O)C(O)C%12O)C%11O)C(O)C%10O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L10 mock treatment 156760.0 -13300.0 -0.36 150320.0 -31500.0 -0.85 -0.855 -0.9251 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L11 compound treatment 12800.0 -157000.0 -4.21 11920.0 -170000.0 -4.6 -6.2273 -0.999 3616667 ACon1_002412 CC1OC(OC2C(O)C(O)C(C)OC2OC3(C)CC(OC4OC(CO)C(O)C(OC(=O)C)C4O)C5C(CCC6C(C)(C)CCCC65C)O3)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L12 mock treatment 179040.0 8960.0 0.24 150800.0 -31000.0 -0.84 -0.4244 -0.4859 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L13 compound treatment 155800.0 -14300.0 -0.38 153360.0 -28500.0 -0.77 -0.8149 -0.9476 3558283 ACon1_002413 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@@H](O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)[C@H](O)C[C@]5(C)C4CC[C@]23C)O[C@@]%111CCC(C)CO%11 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L14 mock treatment 160120.0 -9960.0 -0.27 174960.0 -6860.0 -0.19 -0.3197 -0.9844 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L15 mock treatment 181520.0 11400.0 0.31 151640.0 -30200.0 -0.82 -0.3614 -0.4142 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L16 mock treatment 156320.0 -13800.0 -0.37 156520.0 -25300.0 -0.68 -0.7446 -0.9576 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L17 compound treatment 169000.0 -1080.0 -0.03 156760.0 -25100.0 -0.68 -0.5002 -0.7366 3559686 ACon1_002414 COc1ccc(C[C@H]2COC(=O)[C@]2(O)Cc3ccc(O)c(OC)c3)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L18 mock treatment 138200.0 -31900.0 -0.85 165960.0 -15900.0 -0.43 -0.9066 -0.9496 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L19 compound treatment 175040.0 4960.0 0.13 172000.0 -9820.0 -0.27 -0.0942 -0.317 3557479 ACon1_002415 CC(=CCc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccc(O)c(O)c3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L20 mock treatment 138120.0 -32000.0 -0.85 161400.0 -20400.0 -0.55 -0.9954 -0.9777 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L21 compound treatment 148640.0 -21400.0 -0.57 166240.0 -15600.0 -0.42 -0.7038 -0.9886 3558013 ACon1_002416 CC(=O)O[C@H]1CC(C)(C)CC2[C@@]31CO[C@]42CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@H]9OC[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]7O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L22 mock treatment 146880.0 -23200.0 -0.62 172360.0 -9460.0 -0.26 -0.6199 -0.9234 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L23 mock treatment 160640.0 -9440.0 -0.25 183520.0 1700.0 0.05 -0.146 -0.5688 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 L24 mock treatment 153120.0 -17000.0 -0.45 152360.0 -29500.0 -0.8 -0.8847 -0.9643 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M01 compound treatment 172960.0 2880.0 0.08 173720.0 -8100.0 -0.22 -0.1006 -0.4329 3557425 ACon1_002417 C/C=C(\C)/C(=O)OC1CCC(=O)OC1\C=C\C(O)C(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M02 compound treatment 169240.0 -841.0 -0.02 204760.0 22900.0 0.62 0.4233 0.681 3557333 ACon1_002418 Cc1cc2cc(O)cc(O)c2c(=O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M03 compound treatment 184280.0 14200.0 0.38 159400.0 -22400.0 -0.61 -0.1606 -0.2243 3559679 ACon1_002419 COC(=O)[C@@H]1C[C@@H](O)C[C@]2(C)[C@@H]1CC[C@]3(C[C@H]4CC[C@H]32)[C@@H](O)C4=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M04 compound treatment 14760.0 -155000.0 -4.15 11720.0 -170000.0 -4.61 -6.194 -0.9987 1110474 ACon1_002420 COc1ccc2c(=O)c(O)c(oc2c1)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M05 compound treatment 174120.0 4040.0 0.11 155560.0 -26300.0 -0.71 -0.4263 -0.5928 3553164 ACon1_002421 C1Oc2ccc(cc2O1)[C@H]3OC[C@@H]4[C@H](OC[C@H]34)c5ccc6OCOc6c5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M06 compound treatment 180000.0 9920.0 0.27 159320.0 -22500.0 -0.61 -0.2431 -0.3659 3557719 ACon1_002422 CCCCC/C=C/C=C/C(O)CCCCCCCC(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M07 compound treatment 27120.0 -143000.0 -3.82 17000.0 -165000.0 -4.46 -5.8592 -0.997 3616668 ACon1_002423 CO[C@H]1C[C@H](C)[C@@H](OC)C2=CC(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M08 compound treatment 71120.0 -99000.0 -2.65 59680.0 -122000.0 -3.31 -4.2099 -0.9939 3559706 ACon1_002424 COc1cc(O)c2c(=O)cc(oc2c1)c3cc(OC)c(OC)c(O)c3OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M09 mock treatment 167680.0 -2400.0 -0.06 145760.0 -36100.0 -0.98 -0.7357 -0.752 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M10 mock treatment 162400.0 -7680.0 -0.21 163680.0 -18100.0 -0.49 -0.4925 -0.9252 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M11 compound treatment 13240.0 -157000.0 -4.2 12000.0 -170000.0 -4.6 -6.2174 -0.999 3558746 ACon1_002425 COc1cc(/C=C/CO)ccc1OC\C=C(/C)\CCC=C(C)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M12 compound treatment 32720.0 -137000.0 -3.67 30440.0 -151000.0 -4.1 -5.496 -0.9985 3616671 ACon1_002426 COc1c(O)cc2C(Oc3cc(C)oc(=O)c3)C(C)OC(=O)c2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M13 mock treatment 157160.0 -12900.0 -0.35 162880.0 -18900.0 -0.51 -0.6069 -0.9816 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M14 mock treatment 182880.0 12800.0 0.34 178760.0 -3060.0 -0.08 0.1835 0.521 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M15 compound treatment 152760.0 -17300.0 -0.46 144160.0 -37700.0 -1.02 -1.0485 -0.9363 3554561 ACon1_002427 COC(=O)[C@]1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(=C1c3ccc(O)cc3)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M16 compound treatment 194880.0 24800.0 0.66 185000.0 3180.0 0.09 0.5299 0.7923 3616673 ACon1_002428 COC(=O)[C@]1(O)[C@H](O)C(=O)C(=C1/C=C/C)Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M17 compound treatment 183840.0 13800.0 0.37 155040.0 -26800.0 -0.72 -0.2524 -0.3104 3554697 ACon1_002429 COC(=O)c1c(O)cc(C)cc1Oc2c(O)cc(OC)cc2CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M18 compound treatment 165080.0 -5000.0 -0.13 151400.0 -30400.0 -0.82 -0.6769 -0.8113 3616676 ACon1_002430 COc1cc(O)cc(C)c1C(=O)OC2C(CO)OC(C2OC(=O)C)n3ccc(=O)[nH]c3=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M19 compound treatment 157680.0 -12400.0 -0.33 195200.0 13400.0 0.36 0.0216 0.044 3616679 ACon1_002431 COC(CC(c1c(O)cc2cc(C)oc(=O)c2c1O)c3c(O)cc4cc(C)oc(=O)c4c3O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M20 compound treatment 155480.0 -14600.0 -0.39 167360.0 -14500.0 -0.39 -0.553 -1.0 3616682 ACon1_002432 OC[C@H]1O[C@@H](Oc2c(O)cccc2COC(=O)C3(O)C4C5C6C7C5C(C7C(O)(C(=O)OCc8cccc(O)c8O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C(=O)C64)C3=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M21 compound treatment 166480.0 -3600.0 -0.1 200200.0 18400.0 0.5 0.2838 0.5598 3552105 ACon1_002433 C/C=C/C1OC2=C(C(O)C1O)C(=O)OC2=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M22 compound treatment 184160.0 14100.0 0.38 171520.0 -10300.0 -0.28 0.0691 0.1475 3616684 ACon1_002434 CC1CCC2(CCC3(C(=O)O)C(=CCC4C5(C)CCC(OC6OC(C)C(O)C(=O)C6O)C(C)(C)C5CCC43C)C2C1C)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M23 compound treatment 180240.0 10200.0 0.27 167000.0 -14800.0 -0.4 -0.0915 -0.1889 3559395 ACon1_002435 C/C=C\1/[C@H](CC(=O)OCCc2ccc(O)cc2)C(=CO[C@H]1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 M24 compound treatment 158880.0 -11200.0 -0.3 158680.0 -23100.0 -0.63 -0.6548 -0.943 3559231 ACon1_002436 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)C)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N01 compound treatment 177240.0 7160.0 0.19 183560.0 1740.0 0.05 0.1687 0.8556 2090630 ACon1_002437 CC1OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)C(OC6OC(C)C(O)C(O)C6O)C(O)C2O)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N02 mock treatment 189880.0 19800.0 0.53 174280.0 -7540.0 -0.2 0.2302 0.4055 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N03 compound treatment 187080.0 17000.0 0.45 169080.0 -12700.0 -0.34 0.0777 0.1361 3616685 ACon1_002438 CC(=CCc1cc2C(=O)[C@H](O)[C@H](Oc2c(CC=C(C)C)c1O)c3ccc(O)cc3)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N04 mock treatment 170000.0 -81.4 0.0 195240.0 13400.0 0.36 0.2554 0.7029 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N05 compound treatment 43320.0 -127000.0 -3.39 22960.0 -159000.0 -4.3 -5.4387 -0.9931 3616688 ACon1_002439 C[C@]12C[C@H](OC(=O)[C@H]2CC[C@]3(C)[C@H]1CCC=C3C(=O)O)c4ccoc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N06 mock treatment 197840.0 27800.0 0.74 183680.0 1860.0 0.05 0.5607 0.7534 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N07 compound treatment 66240.0 -104000.0 -2.78 73160.0 -109000.0 -2.94 -4.0442 -0.9996 3616690 ACon1_002440 COc1cc2C[C@H]3COC(=O)[C@@H]3Cc4cc5OCOc5cc4-c2c(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N08 mock treatment 157240.0 -12800.0 -0.34 162240.0 -19600.0 -0.53 -0.6177 -0.9779 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N09 mock treatment 173280.0 3200.0 0.09 162240.0 -19600.0 -0.53 -0.3143 -0.5854 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N10 mock treatment 159160.0 -10900.0 -0.29 179960.0 -1860.0 -0.05 -0.2422 -0.8169 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N11 compound treatment 183600.0 13500.0 0.36 197760.0 15900.0 0.43 0.5609 0.9961 3616692 ACon1_002441 CO[C@@H]1[C@@H](O)[C@@H](O[C@H]2CC[C@]3(C)C4C[C@@H]5C(=C)[C@H](CC[C@]5(O)[C@@H]4CC[C@@H]3C2)C6=CC(=O)OC6)O[C@@H](C)[C@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N12 mock treatment 171360.0 1280.0 0.03 160160.0 -21700.0 -0.59 -0.3904 -0.6647 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N13 mock treatment 178440.0 8360.0 0.22 164680.0 -17100.0 -0.46 -0.17 -0.3301 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N14 mock treatment 171880.0 1800.0 0.05 169920.0 -11900.0 -0.32 -0.1938 -0.5949 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N15 compound treatment 74200.0 -95900.0 -2.56 90320.0 -91500.0 -2.48 -3.5651 -0.9998 3616695 ACon1_002442 COc1cc2nc3occc3c(OC)c2cc1OCC(O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N16 mock treatment 168520.0 -1560.0 -0.04 159920.0 -21900.0 -0.59 -0.4487 -0.755 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N17 compound treatment 162240.0 -7840.0 -0.21 163520.0 -18300.0 -0.5 -0.4986 -0.9268 3559633 ACon1_002443 C/C(=C/CCC(C)(O)C=C)/CCC(=O)C(C)(C)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N18 mock treatment 155720.0 -14400.0 -0.38 156960.0 -24900.0 -0.67 -0.7475 -0.9646 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N19 compound treatment 179400.0 9320.0 0.25 179040.0 -2780.0 -0.08 0.1231 0.4726 3558393 ACon1_002444 CC(C)C1CCC(=CCCC2(C)OC2C1OC3OC(COC(=O)C)C(O)C(O)C3O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N20 mock treatment 176120.0 6040.0 0.16 172920.0 -8900.0 -0.24 -0.0561 -0.1935 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N21 compound treatment 171720.0 1640.0 0.04 163400.0 -18400.0 -0.5 -0.3216 -0.6425 3558493 ACon1_002445 COc1cc(CC2COC(C2COC(=O)/C=C/c3ccc(O)cc3)c4ccc(O)c(OC)c4)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N22 mock treatment 194640.0 24600.0 0.66 168360.0 -13500.0 -0.36 0.2069 0.2754 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N23 mock treatment 148560.0 -21500.0 -0.58 170840.0 -11000.0 -0.3 -0.6172 -0.9527 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 N24 mock treatment 162720.0 -7360.0 -0.2 172480.0 -9340.0 -0.25 -0.318 -0.9924 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O01 compound treatment 173360.0 3280.0 0.09 178960.0 -2860.0 -0.08 0.0073 0.0623 3557529 ACon1_002446 COc1cc(OC)c2C(=O)CC(Oc2c1O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O02 compound treatment 59080.0 -111000.0 -2.97 57160.0 -125000.0 -3.37 -4.4859 -0.998 3559907 ACon1_002447 CC1(C2CC3CC21)C3(C)CCC(O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O03 compound treatment 12800.0 -157000.0 -4.21 10960.0 -171000.0 -4.63 -6.2456 -0.9989 3559525 ACon1_002448 O[C@]12CCC(=C)[C@@H]3CCC(=C)[C@@H]3[C@H]2OC(=O)C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O04 compound treatment 207080.0 37000.0 0.99 191760.0 9940.0 0.27 0.8901 0.8679 3559658 ACon1_002449 COc1ccc(CCC(=O)c2ccc(OC)cc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O05 compound treatment 192840.0 22800.0 0.61 154520.0 -27300.0 -0.74 -0.0921 -0.0962 360 ACon1_002450 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O06 compound treatment 193840.0 23800.0 0.64 191720.0 9900.0 0.27 0.6389 0.9263 3555974 ACon1_002451 OCCCCCCC(C(=O)O)C(=C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O07 compound treatment 167840.0 -2240.0 -0.06 155520.0 -26300.0 -0.71 -0.5458 -0.7639 3559619 ACon1_002452 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(CO)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O08 compound treatment 181360.0 11300.0 0.3 156120.0 -25700.0 -0.7 -0.2786 -0.3674 3557500 ACon1_002453 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/CC/C=C(\CO)/C[C@H]2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O09 compound treatment 168040.0 -2040.0 -0.05 173040.0 -8780.0 -0.24 -0.2067 -0.8475 3553872 ACon1_002454 CC1(C)O[C@H]2CC(=O)OC[C@@]23[C@H]1CC(=O)[C@]4(C)[C@@H]3CC[C@@]5(C)[C@@H](OC(=O)C=C54)c6ccoc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O10 compound treatment 163600.0 -6480.0 -0.17 162360.0 -19500.0 -0.53 -0.4951 -0.8927 3616698 ACon1_002455 CC1CCC(O)C2C=CC(C)(O)C(C)(C12)C(=O)CCO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O11 mock treatment 153920.0 -16200.0 -0.43 192440.0 10600.0 0.29 -0.1024 -0.1971 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O12 mock treatment 176280.0 6200.0 0.17 182000.0 181.0 0.0 0.1207 0.7277 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O13 compound treatment 64080.0 -106000.0 -2.84 50240.0 -132000.0 -3.56 -4.5238 -0.9936 3554856 ACon1_002456 COc1cc(C=C)cc2c(=O)oc3c(cc(OC)c4c(O)ccc([C@@H]5O[C@H](C)[C@H](O)[C@@H]([C@H]5O)N(C)C)c34)c12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O14 compound treatment 184280.0 14200.0 0.38 183120.0 1300.0 0.04 0.2935 0.7694 3559702 ACon1_002457 O[C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O15 compound treatment 161360.0 -8720.0 -0.23 163760.0 -18100.0 -0.49 -0.5107 -0.9427 3553713 ACon1_002458 CC(CCCCC(O)C(CO)C(=O)O)C/C(=C/C(=C/C(=O)O)/C)/C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O16 compound treatment 170520.0 439.0 0.01 182800.0 981.0 0.03 0.0271 0.9325 3553071 ACon1_002459 C[C@H]1[C@H](O)CCC2=CC(=O)C(=C(C)C)C[C@]12CO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O17 compound treatment 164880.0 -5200.0 -0.14 195120.0 13300.0 0.36 0.1562 0.4047 3553691 ACon1_002460 CC(CC(=O)N)OC(=O)c1cc(Cl)cc(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O18 compound treatment 14200.0 -156000.0 -4.17 12120.0 -170000.0 -4.59 -6.197 -0.9988 3616699 ACon1_002461 CC(=O)O[C@@]1(C)C[C@@H](OC(=O)/C=C/c2ccc(O)cc2)[C@H]3[C@@H]1C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O19 compound treatment 225320.0 55200.0 1.48 178280.0 -3540.0 -0.1 0.9771 0.6599 3559916 ACon1_002462 CC(C)(O)CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)[C@H](O)[C@H](Oc13)c4ccc(O)cc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O20 compound treatment 140080.0 -30000.0 -0.8 171280.0 -10500.0 -0.29 -0.7692 -0.9031 1017609 ACon1_002463 CC(=CCc1c(O)c2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc(O)cc4)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O21 compound treatment 155880.0 -14200.0 -0.38 180760.0 -1060.0 -0.03 -0.2889 -0.7583 3554292 ACon1_002464 CCCCCCCC(O)C(O)C1CC(=CC(=O)O1)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O22 compound treatment 168680.0 -1400.0 -0.04 162680.0 -19100.0 -0.52 -0.3929 -0.7563 3558536 ACon1_002465 CC1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(C)CCC6(CCC54C(=O)O)C(=O)OC7OC(CO)C(O)C(O)C7O)C2(C)C)C(O)C(O)C1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O23 compound treatment 180280.0 10200.0 0.27 176800.0 -5020.0 -0.14 0.0968 0.3177 3616706 ACon1_002466 CC1CC(=O)c2cc(O)c(O)cc2C1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 O24 compound treatment 172000.0 1920.0 0.05 162320.0 -19500.0 -0.53 -0.337 -0.6354 3615046 ACon1_002467 COC1OC2C(N(C)CCc3cc4OCOc4cc23)c5ccc6OCOc6c15 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P01 compound treatment 190240.0 20200.0 0.54 169560.0 -12300.0 -0.33 0.1466 0.2316 3616709 ACon1_002468 C[C@@]1(CCC2C(=CCC3[C@@](C)(CCC[C@]23C)C(=O)O)C1)C=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P02 mock treatment 171040.0 959.0 0.03 177280.0 -4540.0 -0.12 -0.0688 -0.5477 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P03 compound treatment 159400.0 -10700.0 -0.29 146000.0 -35800.0 -0.97 -0.8877 -0.8781 3616713 ACon1_002469 COC(=O)[C@@H](O)[C@@H]1[C@@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C[C@]54O[C@@H]6C([C@@]2(O)C[C@@]1(C)[C@@H]6O)[C@@]35O)c7ccoc7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P04 mock treatment 166200.0 -3880.0 -0.1 177760.0 -4060.0 -0.11 -0.1511 -0.9996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P05 compound treatment 178360.0 8280.0 0.22 165120.0 -16700.0 -0.45 -0.1631 -0.324 3616715 ACon1_002470 OC[C@H]1O[C@@H](Oc2ccc(cc2)c3coc4c([C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P06 mock treatment 174200.0 4120.0 0.11 175800.0 -6020.0 -0.16 -0.0373 -0.1897 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P07 compound treatment 174760.0 4680.0 0.13 177240.0 -4580.0 -0.12 8.0E-4 0.0048 3616718 ACon1_002471 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P08 mock treatment 181600.0 11500.0 0.31 160240.0 -21600.0 -0.58 -0.1952 -0.2956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P09 compound treatment 176320.0 6240.0 0.17 152280.0 -29500.0 -0.8 -0.4475 -0.5478 3616720 ACon1_002472 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCc3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P10 mock treatment 172640.0 2560.0 0.07 170960.0 -10900.0 -0.29 -0.1595 -0.5284 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P11 mock treatment 174560.0 4480.0 0.12 156200.0 -25600.0 -0.69 -0.4057 -0.5764 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P12 mock treatment 173200.0 3120.0 0.08 163640.0 -18200.0 -0.49 -0.289 -0.579 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P13 compound treatment 189560.0 19500.0 0.52 148880.0 -32900.0 -0.89 -0.2621 -0.2538 3616724 ACon1_002473 COc1cc2nc3occc3c(OC)c2cc1OCC(OC(=O)C)C(C)(C)OC(=O)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P14 mock treatment 202360.0 32300.0 0.86 163560.0 -18300.0 -0.49 0.261 0.2623 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P15 compound treatment 183520.0 13400.0 0.36 150920.0 -30900.0 -0.84 -0.3373 -0.3705 3616725 ACon1_002474 CCCCCc1cc(OC)c2CC(O)C(C)(C)Oc2c1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P16 mock treatment 158080.0 -12000.0 -0.32 143120.0 -38700.0 -1.05 -0.9678 -0.8832 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P17 compound treatment 160880.0 -9200.0 -0.25 152600.0 -29200.0 -0.79 -0.7334 -0.8853 1001668 ACon1_002475 CC(=CCCC1(C)Oc2c(C)cc3c4ccccc4[nH]c3c2C=C1)C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P18 mock treatment 163320.0 -6760.0 -0.18 143000.0 -38800.0 -1.05 -0.871 -0.8168 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P19 compound treatment 32080.0 -138000.0 -3.69 12280.0 -170000.0 -4.59 -5.8557 -0.9942 3554138 ACon1_002476 CCC(C)C(=O)O[C@@H]1[C@H]2[C@@H](O)[C@@H](C)C[C@]2(O)C(=O)[C@@H](C)/C=C/C(C)(C)[C@H](O)[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)CC)C1=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P20 mock treatment 149960.0 -20100.0 -0.54 160560.0 -21300.0 -0.58 -0.7875 -0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P21 compound treatment 158520.0 -11600.0 -0.31 159440.0 -22400.0 -0.61 -0.6471 -0.9513 3559753 ACon1_002477 COC1=CC2(CCN(C)[C@@H]3Cc4cc(OC)c(OC)cc42)C3=CC1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P22 mock treatment 168320.0 -1760.0 -0.05 162960.0 -18900.0 -0.51 -0.3943 -0.7691 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P23 mock treatment 166240.0 -3840.0 -0.1 175000.0 -6820.0 -0.18 -0.2032 -0.9617 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2297 P24 mock treatment 170600.0 519.0 0.01 174440.0 -7380.0 -0.2 -0.1314 -0.6564 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A01 compound treatment 201480.0 38300.0 1.02 203760.0 52300.0 1.42 1.7254 0.9874 3213058 CHDI2_000001 NNC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A02 compound treatment 8840.0 -154000.0 -4.13 7240.0 -144000.0 -3.91 -5.6803 -0.9996 3213102 CHDI2_000002 ONC(=O)CCCCCCC(=O)N/N=C/c1c(O)ccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A03 compound treatment 5160.0 -158000.0 -4.23 4120.0 -147000.0 -3.99 -5.8096 -0.9996 3213060 CHDI2_000003 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A04 compound treatment 7200.0 -156000.0 -4.17 4480.0 -147000.0 -3.98 -5.7641 -0.9997 3213106 CHDI2_000004 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A05 compound treatment 18080.0 -145000.0 -3.88 12280.0 -139000.0 -3.77 -5.409 -0.9999 3213064 CHDI2_000005 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A06 compound treatment 44680.0 -118000.0 -3.17 17600.0 -134000.0 -3.62 -4.8041 -0.9978 3213110 CHDI2_000006 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc([N+](=O)[O-])c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A07 compound treatment 13760.0 -149000.0 -4.0 6600.0 -145000.0 -3.92 -5.5995 -1.0 3213068 CHDI2_000007 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A08 compound treatment 209440.0 46300.0 1.24 129040.0 -22400.0 -0.61 0.4455 0.3231 3213114 CHDI2_000008 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(O)ccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A09 compound treatment 11320.0 -152000.0 -4.06 6440.0 -145000.0 -3.93 -5.6487 -0.9999 3213072 CHDI2_000009 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2OCCOc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A10 compound treatment 89760.0 -73400.0 -1.96 16400.0 -135000.0 -3.66 -3.9744 -0.9575 3213118 CHDI2_000010 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)n2ccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A11 compound treatment 118880.0 -44300.0 -1.18 83760.0 -67700.0 -1.83 -2.1341 -0.9777 3213076 CHDI2_000011 ONC(=O)CCCCCCC(=O)N/N=C/COCc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A12 compound treatment 26920.0 -136000.0 -3.64 11840.0 -140000.0 -3.78 -5.2503 -0.9998 3213122 CHDI2_000012 ONC(=O)CCCCCCC(=O)N/N=C/c1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A13 compound treatment 7840.0 -155000.0 -4.15 6080.0 -145000.0 -3.94 -5.7214 -0.9996 3214258 CHDI2_000013 ONC(=O)CCCCCC(=O)N/N=C/c1c(O)ccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A14 compound treatment 183120.0 20000.0 0.53 128440.0 -23000.0 -0.62 -0.0638 -0.0777 3214354 CHDI2_000014 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A15 compound treatment 8480.0 -155000.0 -4.14 6280.0 -145000.0 -3.93 -5.7055 -0.9997 3213080 CHDI2_000015 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A16 compound treatment 7640.0 -156000.0 -4.16 5280.0 -146000.0 -3.96 -5.7405 -0.9997 3213126 CHDI2_000016 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(I)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A17 compound treatment 6960.0 -156000.0 -4.18 4240.0 -147000.0 -3.99 -5.7733 -0.9997 3213084 CHDI2_000017 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A18 compound treatment 27600.0 -136000.0 -3.63 18200.0 -133000.0 -3.61 -5.1156 -1.0 3213130 CHDI2_000018 C/C=C(/C)\C=N\NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A19 compound treatment 33600.0 -130000.0 -3.47 20520.0 -131000.0 -3.55 -4.9577 -0.9999 3213088 CHDI2_000019 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A20 compound treatment 5640.0 -158000.0 -4.21 5040.0 -146000.0 -3.96 -5.7829 -0.9995 3213206 CHDI2_000020 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(s1)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A21 compound treatment 7120.0 -156000.0 -4.17 6000.0 -145000.0 -3.94 -5.7366 -0.9996 3213092 CHDI2_000021 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Br)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A22 compound treatment 35040.0 -128000.0 -3.43 32840.0 -119000.0 -3.21 -4.6947 -0.9995 3213138 CHDI2_000022 Cc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A23 mock treatment 239120.0 76000.0 2.03 230440.0 79000.0 2.14 2.948 0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 A24 mock treatment 222280.0 59100.0 1.58 219040.0 67600.0 1.83 2.4113 0.9974 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B01 compound treatment 239520.0 76400.0 2.04 241320.0 89800.0 2.43 3.1639 0.9962 3213059 CHDI2_000023 NNC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B02 compound treatment 14640.0 -149000.0 -3.97 22680.0 -129000.0 -3.49 -5.275 -0.9979 3213100 CHDI2_000024 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B03 compound treatment 184880.0 21700.0 0.58 196000.0 44500.0 1.21 1.2628 0.944 3213062 CHDI2_000025 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B04 compound treatment 100680.0 -62500.0 -1.67 87360.0 -64100.0 -1.74 -2.4095 -0.9998 3213104 CHDI2_000026 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B05 compound treatment 179880.0 16700.0 0.45 172120.0 20600.0 0.56 0.7111 0.9939 3213066 CHDI2_000027 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B06 compound treatment 157800.0 -5370.0 -0.14 139080.0 -12400.0 -0.34 -0.339 -0.9281 3213108 CHDI2_000028 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B07 compound treatment 145240.0 -17900.0 -0.48 143880.0 -7610.0 -0.21 -0.4847 -0.9288 3213070 CHDI2_000029 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B08 compound treatment 180520.0 17400.0 0.46 156560.0 5070.0 0.14 0.4254 0.8787 3213112 CHDI2_000030 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B09 compound treatment 181400.0 18200.0 0.49 137320.0 -14200.0 -0.38 0.0737 0.1188 3213074 CHDI2_000031 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3OCCOc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B10 compound treatment 165280.0 2110.0 0.06 151080.0 -407.0 -0.01 0.0322 0.559 3213116 CHDI2_000032 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B11 compound treatment 162320.0 -845.0 -0.02 145400.0 -6090.0 -0.16 -0.1325 -0.7967 3213078 CHDI2_000033 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/COCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B12 compound treatment 122120.0 -41000.0 -1.1 106640.0 -44800.0 -1.21 -1.6348 -0.9987 3213120 CHDI2_000034 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2c[nH]c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B13 compound treatment 147600.0 -15600.0 -0.42 145960.0 -5530.0 -0.15 -0.4002 -0.9046 3214500 CHDI2_000035 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B14 mock treatment 171440.0 8270.0 0.22 157080.0 5590.0 0.15 0.2636 0.9829 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B15 compound treatment 188600.0 25400.0 0.68 153360.0 1870.0 0.05 0.5169 0.7577 3213082 CHDI2_000036 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B16 compound treatment 199840.0 36700.0 0.98 152240.0 753.0 0.02 0.7081 0.7217 3213124 CHDI2_000037 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(I)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B17 compound treatment 131240.0 -31900.0 -0.85 92360.0 -59100.0 -1.6 -1.7357 -0.9567 3213086 CHDI2_000038 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B18 compound treatment 203440.0 40300.0 1.08 153160.0 1670.0 0.05 0.7938 0.7362 3213128 CHDI2_000039 C/C=C(/C)\C=N\NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B19 compound treatment 189960.0 26800.0 0.72 179400.0 27900.0 0.76 1.0411 0.9997 3213090 CHDI2_000040 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B20 compound treatment 87680.0 -75500.0 -2.02 65720.0 -85800.0 -2.32 -3.0696 -0.9976 3213204 CHDI2_000041 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B21 compound treatment 175000.0 11800.0 0.32 186160.0 34700.0 0.94 0.8876 0.896 3213094 CHDI2_000042 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Br)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B22 compound treatment 166760.0 3590.0 0.1 189760.0 38300.0 1.04 0.8007 0.7694 3213136 CHDI2_000043 Cc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B23 mock treatment 176480.0 13300.0 0.36 183440.0 32000.0 0.87 0.8635 0.9231 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 B24 mock treatment 261160.0 98000.0 2.62 227640.0 76200.0 2.06 3.3113 0.9929 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C01 compound treatment 38560.0 -125000.0 -3.33 35080.0 -116000.0 -3.15 -4.5852 -0.9996 3213144 CHDI2_000044 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Br)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C02 compound treatment 10280.0 -153000.0 -4.09 12120.0 -139000.0 -3.77 -5.5596 -0.9992 3213186 CHDI2_000045 Cc1ccsc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C03 compound treatment 6280.0 -157000.0 -4.2 5760.0 -146000.0 -3.95 -5.757 -0.9995 3213148 CHDI2_000046 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C04 compound treatment 10040.0 -153000.0 -4.1 7200.0 -144000.0 -3.91 -5.6584 -0.9997 3213190 CHDI2_000047 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C05 compound treatment 6880.0 -156000.0 -4.18 5080.0 -146000.0 -3.96 -5.7587 -0.9996 3213152 CHDI2_000048 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(O)ccc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C06 compound treatment 5960.0 -157000.0 -4.21 5240.0 -146000.0 -3.96 -5.773 -0.9995 3213194 CHDI2_000049 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C07 compound treatment 7120.0 -156000.0 -4.17 5200.0 -146000.0 -3.96 -5.7519 -0.9997 3213156 CHDI2_000050 COc1cc(Br)cc(/C=N/NC(=O)CCCCCCC(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C08 compound treatment 8480.0 -155000.0 -4.14 6080.0 -145000.0 -3.94 -5.7093 -0.9997 3213202 CHDI2_000051 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2ccccc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C09 compound treatment 8880.0 -154000.0 -4.13 6840.0 -145000.0 -3.92 -5.6872 -0.9997 3213160 CHDI2_000052 COc1ccc(Br)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C10 compound treatment 16880.0 -146000.0 -3.91 11640.0 -140000.0 -3.79 -5.444 -0.9999 3213134 CHDI2_000053 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C11 compound treatment 62680.0 -100000.0 -2.69 44080.0 -107000.0 -2.91 -3.9567 -0.9992 3214262 CHDI2_000054 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C12 compound treatment 14280.0 -149000.0 -3.98 9920.0 -142000.0 -3.83 -5.5261 -0.9998 3214366 CHDI2_000055 ONC(=O)CCCCCC(=O)N/N=C/c1c(F)c(F)c(F)c(F)c1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C13 compound treatment 25400.0 -138000.0 -3.69 22400.0 -129000.0 -3.49 -5.0769 -0.9996 3213164 CHDI2_000056 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C14 compound treatment 25160.0 -138000.0 -3.69 15320.0 -136000.0 -3.69 -5.2169 -1.0 3213198 CHDI2_000057 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C15 compound treatment 121280.0 -41900.0 -1.12 77400.0 -74100.0 -2.01 -2.2105 -0.9622 3214266 CHDI2_000058 ONC(=O)CCCCCC(=O)N/N=C/c1ccc([N+](=O)[O-])c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C16 compound treatment 138200.0 -25000.0 -0.67 127200.0 -24300.0 -0.66 -0.9371 -1.0 3214370 CHDI2_000059 ONC(=O)CCCCCC(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C17 compound treatment 18840.0 -144000.0 -3.86 14480.0 -137000.0 -3.71 -5.3525 -0.9998 3213168 CHDI2_000060 ONC(=O)CCCCCCC(=O)N/N=C/c1cc2OCOc2cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C18 compound treatment 9080.0 -154000.0 -4.12 6000.0 -145000.0 -3.94 -5.6995 -0.9997 3213210 CHDI2_000061 ONC(=O)CCCCCCC(=O)N/N=C/c1c(F)c(F)c(F)c(F)c1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C19 compound treatment 17360.0 -146000.0 -3.9 10200.0 -141000.0 -3.82 -5.4625 -1.0 3213172 CHDI2_000062 ONC(=O)CCCCCCC(=O)N/N=C/c1cccnc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C20 compound treatment 152280.0 -10900.0 -0.29 144920.0 -6570.0 -0.18 -0.3316 -0.972 3213214 CHDI2_000063 ONC(=O)CCCCCCC(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C21 compound treatment 12960.0 -150000.0 -4.02 11440.0 -140000.0 -3.79 -5.522 -0.9996 3213176 CHDI2_000064 ONC(=O)CCCCCCC(=O)N/N=C/c1ccncc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C22 compound treatment 15520.0 -148000.0 -3.95 10240.0 -141000.0 -3.82 -5.4965 -0.9999 3213218 CHDI2_000065 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C23 mock treatment 178000.0 14800.0 0.4 152920.0 1430.0 0.04 0.308 0.7726 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 C24 mock treatment 183000.0 19800.0 0.53 175840.0 24400.0 0.66 0.8414 0.9942 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D01 compound treatment 164360.0 1190.0 0.03 178080.0 26600.0 0.72 0.5317 0.7378 3213146 CHDI2_000066 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Br)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D02 compound treatment 171880.0 8710.0 0.23 170440.0 19000.0 0.51 0.5277 0.9363 3213184 CHDI2_000067 Cc1ccsc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D03 compound treatment 56120.0 -107000.0 -2.86 54960.0 -96500.0 -2.61 -3.8725 -0.999 3213150 CHDI2_000068 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D04 compound treatment 209720.0 46600.0 1.25 201320.0 49800.0 1.35 1.8345 0.9992 3213188 CHDI2_000069 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCCC(=O)Nc3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D05 compound treatment 70280.0 -92900.0 -2.48 48920.0 -103000.0 -2.78 -3.7203 -0.9985 3213154 CHDI2_000070 Oc1ccc(Br)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D06 compound treatment 79120.0 -84000.0 -2.25 48480.0 -103000.0 -2.79 -3.5615 -0.9943 3213192 CHDI2_000071 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D07 compound treatment 46080.0 -117000.0 -3.13 56760.0 -94700.0 -2.56 -4.0279 -0.9951 3213158 CHDI2_000072 COc1cc(Br)cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D08 compound treatment 203000.0 39800.0 1.07 194520.0 43000.0 1.17 1.5772 0.999 3213200 CHDI2_000073 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3ccccc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D09 compound treatment 76120.0 -87000.0 -2.33 54000.0 -97500.0 -2.64 -3.5126 -0.998 3213162 CHDI2_000074 COc1ccc(Br)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D10 compound treatment 157200.0 -5970.0 -0.16 141200.0 -10300.0 -0.28 -0.3098 -0.9651 3213132 CHDI2_000075 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D11 compound treatment 138200.0 -25000.0 -0.67 130360.0 -21100.0 -0.57 -0.8766 -0.997 3214504 CHDI2_000076 ONC(=O)CCCCCC(=O)N/N=C/c1c(O)cc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D12 mock treatment 195680.0 32500.0 0.87 155840.0 4350.0 0.12 0.6983 0.7957 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D13 compound treatment 81720.0 -81400.0 -2.18 71880.0 -79600.0 -2.16 -3.0644 -1.0 3213166 CHDI2_000077 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D14 compound treatment 190600.0 27400.0 0.73 196640.0 45200.0 1.22 1.3833 0.9702 3213196 CHDI2_000078 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D15 compound treatment 181600.0 18400.0 0.49 169560.0 18100.0 0.49 0.6947 1.0 3214508 CHDI2_000079 COc1cc(OC)c(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D16 compound treatment 158760.0 -4410.0 -0.12 152440.0 953.0 0.03 -0.0651 -0.5394 3214630 CHDI2_000080 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D17 compound treatment 91720.0 -71400.0 -1.91 64360.0 -87100.0 -2.36 -3.0192 -0.9945 3213170 CHDI2_000081 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D18 compound treatment 121800.0 -41400.0 -1.11 10960.0 -141000.0 -3.8 -3.4725 -0.8764 3213208 CHDI2_000082 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D19 compound treatment 205000.0 41800.0 1.12 137000.0 -14500.0 -0.39 0.5139 0.4334 3213174 CHDI2_000083 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccnc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D20 compound treatment 177920.0 14800.0 0.39 171720.0 20200.0 0.55 0.6664 0.9871 3213212 CHDI2_000084 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D21 compound treatment 163200.0 34.6 0.0 167880.0 16400.0 0.44 0.3145 0.7086 3213178 CHDI2_000085 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccncc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D22 compound treatment 189120.0 26000.0 0.69 167640.0 16200.0 0.44 0.8001 0.9752 3213216 CHDI2_000086 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D23 mock treatment 167760.0 4590.0 0.12 172440.0 21000.0 0.57 0.488 0.8408 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 D24 mock treatment 199040.0 35900.0 0.96 162920.0 11400.0 0.31 0.8974 0.89 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E01 compound treatment 194520.0 31400.0 0.84 155120.0 3630.0 0.1 0.6626 0.7847 3214270 CHDI2_000087 ONC(=O)CCCCCC(=O)N/N=C/c1cc(O)ccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E02 compound treatment 8320.0 -155000.0 -4.14 7320.0 -144000.0 -3.9 -5.6886 -0.9996 3214374 CHDI2_000088 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E03 compound treatment 6760.0 -156000.0 -4.18 6480.0 -145000.0 -3.93 -5.7342 -0.9995 3213224 CHDI2_000089 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Br)s1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E04 compound treatment 6480.0 -157000.0 -4.19 6920.0 -145000.0 -3.91 -5.731 -0.9994 3213262 CHDI2_000090 ONC(=O)CCCCCCC(=O)N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E05 compound treatment 6480.0 -157000.0 -4.19 5680.0 -146000.0 -3.95 -5.7548 -0.9996 3213228 CHDI2_000091 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E06 compound treatment 23000.0 -140000.0 -3.75 24400.0 -127000.0 -3.44 -5.084 -0.9991 3213266 CHDI2_000092 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E07 compound treatment 6800.0 -156000.0 -4.18 5600.0 -146000.0 -3.95 -5.7503 -0.9996 3213232 CHDI2_000093 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E08 compound treatment 45200.0 -118000.0 -3.16 29040.0 -122000.0 -3.31 -4.5752 -0.9997 3213270 CHDI2_000094 ONC(=O)CCCCCCC(=O)N/N=C/c1cccnc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E09 compound treatment 141760.0 -21400.0 -0.57 116520.0 -35000.0 -0.95 -1.0742 -0.971 3214274 CHDI2_000095 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)n2ccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E10 compound treatment 11440.0 -152000.0 -4.06 9320.0 -142000.0 -3.85 -5.5913 -0.9996 3214378 CHDI2_000096 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(Oc2ccccc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E11 compound treatment 42600.0 -121000.0 -3.22 44200.0 -107000.0 -2.9 -4.3342 -0.9986 3213236 CHDI2_000097 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E12 compound treatment 127840.0 -35300.0 -0.94 124000.0 -27500.0 -0.74 -1.1943 -0.993 3213274 CHDI2_000098 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E13 compound treatment 113040.0 -50100.0 -1.34 109440.0 -42000.0 -1.14 -1.753 -0.9967 3213240 CHDI2_000099 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E14 compound treatment 158720.0 -4450.0 -0.12 142880.0 -8610.0 -0.23 -0.2488 -0.9513 3213278 CHDI2_000100 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E15 compound treatment 13480.0 -150000.0 -4.0 10200.0 -141000.0 -3.82 -5.5359 -0.9997 3213244 CHDI2_000101 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E16 compound treatment 15120.0 -148000.0 -3.96 13600.0 -138000.0 -3.73 -5.4398 -0.9996 3213282 CHDI2_000102 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)N2CCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E17 compound treatment 36120.0 -127000.0 -3.4 26440.0 -125000.0 -3.39 -4.7968 -1.0 3214278 CHDI2_000103 ONC(=O)CCCCCC(=O)N/N=C/c1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E18 compound treatment 10760.0 -152000.0 -4.08 8240.0 -143000.0 -3.88 -5.6248 -0.9997 3214418 CHDI2_000104 ONC(=O)CCCCCC(=O)N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E19 compound treatment 159880.0 -3290.0 -0.09 145240.0 -6250.0 -0.17 -0.1817 -0.9535 3213248 CHDI2_000105 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E20 compound treatment 23560.0 -140000.0 -3.73 22600.0 -129000.0 -3.49 -5.1078 -0.9994 3213286 CHDI2_000106 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E21 compound treatment 156160.0 -7010.0 -0.19 142040.0 -9450.0 -0.26 -0.3133 -0.9883 3213252 CHDI2_000107 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E22 compound treatment 172840.0 9670.0 0.26 154320.0 2830.0 0.08 0.2372 0.8789 3213290 CHDI2_000108 CCCCCCC/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E23 mock treatment 158960.0 -4210.0 -0.11 143680.0 -7810.0 -0.21 -0.229 -0.9564 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 E24 mock treatment 155960.0 -7210.0 -0.19 166280.0 14800.0 0.4 0.1469 0.3305 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F01 compound treatment 149160.0 -14000.0 -0.37 134640.0 -16800.0 -0.46 -0.5874 -0.9952 3214512 CHDI2_000109 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F02 compound treatment 160000.0 -3170.0 -0.08 155600.0 4110.0 0.11 0.0189 0.1349 3214634 CHDI2_000110 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F03 compound treatment 163080.0 -85.4 0.0 123080.0 -28400.0 -0.77 -0.5454 -0.7092 3213226 CHDI2_000111 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Br)s2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F04 compound treatment 99960.0 -63200.0 -1.69 90200.0 -61300.0 -1.66 -2.3687 -1.0 3213260 CHDI2_000112 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F05 compound treatment 120080.0 -43100.0 -1.15 120600.0 -30900.0 -0.84 -1.4062 -0.9876 3213230 CHDI2_000113 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F06 compound treatment 162400.0 -765.0 -0.02 158600.0 7110.0 0.19 0.1217 0.6284 3213264 CHDI2_000114 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F07 compound treatment 18120.0 -145000.0 -3.88 14840.0 -137000.0 -3.7 -5.3593 -0.9997 3213234 CHDI2_000115 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F08 compound treatment 148840.0 -14300.0 -0.38 155640.0 4150.0 0.11 -0.1914 -0.4794 3213268 CHDI2_000116 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F09 compound treatment 130800.0 -32400.0 -0.87 150360.0 -1130.0 -0.03 -0.6337 -0.7316 3214516 CHDI2_000117 CC(C)(C)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F10 compound treatment 144560.0 -18600.0 -0.5 154360.0 2870.0 0.08 -0.2969 -0.5894 3214638 CHDI2_000118 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F11 compound treatment 170360.0 7190.0 0.19 161280.0 9790.0 0.27 0.3236 0.9876 3213238 CHDI2_000119 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F12 compound treatment 126840.0 -36300.0 -0.97 139920.0 -11600.0 -0.31 -0.9085 -0.8899 3213272 CHDI2_000120 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F13 compound treatment 150800.0 -12400.0 -0.33 146280.0 -5210.0 -0.14 -0.3336 -0.9277 3213242 CHDI2_000121 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F14 compound treatment 84400.0 -78800.0 -2.11 87680.0 -63800.0 -1.73 -2.7112 -0.9951 3213276 CHDI2_000122 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F15 compound treatment 141680.0 -21500.0 -0.57 132480.0 -19000.0 -0.51 -0.7702 -0.9985 3213246 CHDI2_000123 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F16 compound treatment 145040.0 -18100.0 -0.48 166800.0 15300.0 0.41 -0.0497 -0.0779 3213280 CHDI2_000124 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F17 compound treatment 113440.0 -49700.0 -1.33 97520.0 -54000.0 -1.46 -1.9736 -0.9989 3214520 CHDI2_000125 CC1=C(C/C=N/NC(=O)CCCCCC(=O)NO)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F18 compound treatment 138560.0 -24600.0 -0.66 138280.0 -13200.0 -0.36 -0.7182 -0.9589 3214641 CHDI2_000126 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F19 compound treatment 184280.0 21100.0 0.56 144640.0 -6850.0 -0.19 0.2683 0.4514 3213250 CHDI2_000127 OC(=O)c1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F20 compound treatment 119600.0 -43600.0 -1.17 112240.0 -39200.0 -1.06 -1.5753 -0.9989 3213284 CHDI2_000128 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F21 compound treatment 181240.0 18100.0 0.48 149920.0 -1570.0 -0.04 0.3119 0.6426 3213254 CHDI2_000129 OC(=O)c1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F22 compound treatment 179120.0 16000.0 0.43 160720.0 9230.0 0.25 0.4785 0.9675 3213288 CHDI2_000130 CCCCCCC/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F23 mock treatment 170320.0 7150.0 0.19 168360.0 16900.0 0.46 0.4583 0.9254 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 F24 mock treatment 155280.0 -7890.0 -0.21 153960.0 2470.0 0.07 -0.1018 -0.46 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G01 compound treatment 7240.0 -156000.0 -4.17 7560.0 -144000.0 -3.9 -5.7044 -0.9994 3213296 CHDI2_000131 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G02 compound treatment 13800.0 -149000.0 -4.0 14240.0 -137000.0 -3.72 -5.4525 -0.9993 3213336 CHDI2_000132 ONC(=O)CCCCCCC(=O)N/N=C/c1cccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G03 compound treatment 7800.0 -155000.0 -4.16 7840.0 -144000.0 -3.89 -5.6885 -0.9994 3214282 CHDI2_000133 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(I)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G04 compound treatment 71880.0 -91300.0 -2.44 89400.0 -62100.0 -1.68 -2.9151 -0.9834 3214422 CHDI2_000134 ONC(=O)CCCCCC(=O)N/N=C/c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G05 compound treatment 16360.0 -147000.0 -3.93 14600.0 -137000.0 -3.71 -5.3972 -0.9996 3213300 CHDI2_000135 ONC(=O)CCCCCCC(=O)N/N=C/c1cccnc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G06 compound treatment 8400.0 -155000.0 -4.14 8400.0 -143000.0 -3.87 -5.6664 -0.9994 3213340 CHDI2_000136 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G07 compound treatment 10880.0 -152000.0 -4.07 9880.0 -142000.0 -3.83 -5.5912 -0.9995 3213304 CHDI2_000137 ONC(=O)CCCCCCC(=O)N/N=C/C=C/c1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G08 compound treatment 149640.0 -13500.0 -0.36 151760.0 273.0 0.01 -0.2506 -0.6925 3213344 CHDI2_000138 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G09 compound treatment 130320.0 -32800.0 -0.88 132480.0 -19000.0 -0.51 -0.9851 -0.9675 3213308 CHDI2_000139 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G10 compound treatment 134600.0 -28600.0 -0.76 150840.0 -647.0 -0.02 -0.5527 -0.7231 3213348 CHDI2_000140 ONC(=O)CCCCCCC(=O)N/N=C/c1c(O)cc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G11 compound treatment 138880.0 -24300.0 -0.65 144280.0 -7210.0 -0.2 -0.5973 -0.8806 3213312 CHDI2_000141 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G12 compound treatment 127520.0 -35600.0 -0.95 138040.0 -13400.0 -0.36 -0.9316 -0.9128 3213352 CHDI2_000142 COc1cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G13 compound treatment 18160.0 -145000.0 -3.88 15760.0 -136000.0 -3.67 -5.3409 -0.9996 3213314 CHDI2_000143 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(C#N)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G14 compound treatment 88280.0 -74900.0 -2.0 85840.0 -65600.0 -1.78 -2.6731 -0.9982 3213356 CHDI2_000144 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G15 compound treatment 146480.0 -16700.0 -0.45 136120.0 -15400.0 -0.42 -0.6098 -0.9994 3213318 CHDI2_000145 ONC(=O)CCCCCCC(=O)N/N=C/C1CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G16 compound treatment 127160.0 -36000.0 -0.96 125840.0 -25600.0 -0.69 -1.172 -0.9871 3213360 CHDI2_000146 CC(C)(C)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G17 compound treatment 11360.0 -152000.0 -4.06 10840.0 -141000.0 -3.81 -5.5637 -0.9995 3213322 CHDI2_000147 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G18 compound treatment 57000.0 -106000.0 -2.84 53680.0 -97800.0 -2.65 -3.8804 -0.9994 3213364 CHDI2_000148 CC1=C(C/C=N/NC(=O)CCCCCCC(=O)NO)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G19 compound treatment 134960.0 -28200.0 -0.75 118760.0 -32700.0 -0.89 -1.16 -0.9968 3214286 CHDI2_000149 C/C=C(/C)\C=N\NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G20 compound treatment 128000.0 -35200.0 -0.94 149440.0 -2050.0 -0.06 -0.7043 -0.7475 3214426 CHDI2_000150 ONC(=O)CCCCCC(=O)N/N=C/c1cccnc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G21 compound treatment 9960.0 -153000.0 -4.1 9240.0 -142000.0 -3.85 -5.6208 -0.9995 3213326 CHDI2_000151 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)cc(Br)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G22 compound treatment 130160.0 -33000.0 -0.88 122560.0 -28900.0 -0.78 -1.178 -0.9982 3213368 CHDI2_000152 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G23 mock treatment 143560.0 -19600.0 -0.52 142040.0 -9450.0 -0.26 -0.5517 -0.9455 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 G24 mock treatment 146720.0 -16400.0 -0.44 155600.0 4110.0 0.11 -0.2323 -0.512 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H01 compound treatment 126800.0 -36400.0 -0.97 117640.0 -33800.0 -0.92 -1.3358 -0.9996 3213298 CHDI2_000153 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H02 compound treatment 158280.0 -4890.0 -0.13 151080.0 -407.0 -0.01 -0.1002 -0.764 3213334 CHDI2_000154 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H03 compound treatment 151560.0 -11600.0 -0.31 149440.0 -2050.0 -0.06 -0.2587 -0.8204 3214524 CHDI2_000155 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H04 compound treatment 173120.0 9950.0 0.27 152040.0 553.0 0.01 0.1989 0.7457 3214643 CHDI2_000156 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H05 compound treatment 139760.0 -23400.0 -0.63 158640.0 7150.0 0.19 -0.3058 -0.4666 3213302 CHDI2_000157 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccnc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H06 compound treatment 160160.0 -3010.0 -0.08 137680.0 -13800.0 -0.37 -0.3211 -0.84 3213338 CHDI2_000158 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H07 compound treatment 156600.0 -6570.0 -0.18 143320.0 -8170.0 -0.22 -0.2805 -0.9935 3213306 CHDI2_000159 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H08 compound treatment 163000.0 -165.0 0.0 161080.0 9590.0 0.26 0.1805 0.695 3213342 CHDI2_000160 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H09 compound treatment 148760.0 -14400.0 -0.39 147880.0 -3610.0 -0.1 -0.3415 -0.8591 3213310 CHDI2_000161 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H10 compound treatment 122160.0 -41000.0 -1.1 124240.0 -27200.0 -0.74 -1.2972 -0.9814 3213346 CHDI2_000162 Oc1cc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H11 compound treatment 150800.0 -12400.0 -0.33 159240.0 7750.0 0.21 -0.0855 -0.2182 3213313 CHDI2_000163 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H12 compound treatment 151680.0 -11500.0 -0.31 169400.0 17900.0 0.48 0.1257 0.2189 3213350 CHDI2_000164 COc1cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H13 compound treatment 113600.0 -49600.0 -1.33 116840.0 -34600.0 -0.94 -1.6007 -0.9856 3213316 CHDI2_000165 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(C#N)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H14 compound treatment 144200.0 -19000.0 -0.51 166120.0 14600.0 0.4 -0.0786 -0.1221 3213354 CHDI2_000166 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H15 compound treatment 148840.0 -14300.0 -0.38 162520.0 11000.0 0.3 -0.0597 -0.123 3213320 CHDI2_000167 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H16 compound treatment 155560.0 -7610.0 -0.2 149400.0 -2090.0 -0.06 -0.1838 -0.8705 3213358 CHDI2_000168 CC(C)(C)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H17 compound treatment 139240.0 -23900.0 -0.64 177720.0 26200.0 0.71 0.0497 0.0519 3213324 CHDI2_000169 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H18 compound treatment 111480.0 -51700.0 -1.38 120680.0 -30800.0 -0.83 -1.5673 -0.9707 3213362 CHDI2_000170 CC1=C(C/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H19 compound treatment 138040.0 -25100.0 -0.67 154280.0 2790.0 0.08 -0.4218 -0.6236 3214528 CHDI2_000171 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H20 compound treatment 128080.0 -35100.0 -0.94 141440.0 -10000.0 -0.27 -0.8559 -0.876 3214646 CHDI2_000172 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H21 compound treatment 16600.0 -147000.0 -3.92 18880.0 -133000.0 -3.59 -5.3107 -0.999 3213328 CHDI2_000173 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H22 compound treatment 125040.0 -38100.0 -1.02 149080.0 -2410.0 -0.07 -0.7672 -0.7508 3213366 CHDI2_000174 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H23 mock treatment 179440.0 16300.0 0.44 137640.0 -13800.0 -0.37 0.0428 0.0744 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 H24 mock treatment 153160.0 -10000.0 -0.27 144200.0 -7290.0 -0.2 -0.3287 -0.9887 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I01 compound treatment 7040.0 -156000.0 -4.18 7880.0 -144000.0 -3.89 -5.7021 -0.9994 3213374 CHDI2_000175 COc1cc(Cl)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I02 compound treatment 152360.0 -10800.0 -0.29 147840.0 -3650.0 -0.1 -0.2742 -0.8977 3213415 CHDI2_000176 ONC(=O)CCCCCCC(=O)NN=C1CCCCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I03 compound treatment 9080.0 -154000.0 -4.12 10520.0 -141000.0 -3.82 -5.613 -0.9993 3213378 CHDI2_000177 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Cl)cc(Cl)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I04 compound treatment 141800.0 -21400.0 -0.57 157880.0 6390.0 0.17 -0.2817 -0.4718 3213417 CHDI2_000178 ONC(=O)CCCCCCC(=O)NN=C1CCCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I05 compound treatment 10160.0 -153000.0 -4.09 10960.0 -141000.0 -3.8 -5.5841 -0.9993 3214362 CHDI2_000179 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(s1)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I06 compound treatment 145640.0 -17500.0 -0.47 132000.0 -19500.0 -0.53 -0.7045 -0.9983 3214430 CHDI2_000180 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCC(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I07 compound treatment 100560.0 -62600.0 -1.67 104320.0 -47200.0 -1.28 -2.0871 -0.991 3213382 CHDI2_000181 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)cc([N+](=O)[O-])c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I08 compound treatment 128960.0 -34200.0 -0.91 144320.0 -7170.0 -0.19 -0.7842 -0.8384 3213419 CHDI2_000182 ONC(=O)CCCCCCC(=O)NN=C1CCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I09 compound treatment 10640.0 -153000.0 -4.08 11240.0 -140000.0 -3.8 -5.5697 -0.9994 3213386 CHDI2_000183 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I10 mock treatment 135000.0 -28200.0 -0.75 152680.0 1190.0 0.03 -0.5099 -0.6762 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I11 compound treatment 13520.0 -150000.0 -4.0 17320.0 -134000.0 -3.63 -5.3988 -0.9988 3213390 CHDI2_000184 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2OCCc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I12 compound treatment 11040.0 -152000.0 -4.07 10720.0 -141000.0 -3.81 -5.5721 -0.9995 3213422 CHDI2_000185 COc1cc(Br)c(/C=N/NC(=O)CCCCCCC(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I13 compound treatment 38280.0 -125000.0 -3.34 51720.0 -99800.0 -2.7 -4.272 -0.9944 3213394 CHDI2_000186 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I14 compound treatment 144360.0 -18800.0 -0.5 145920.0 -5570.0 -0.15 -0.4623 -0.8803 3213426 CHDI2_000187 ONC(=O)CCCCCCC(=O)N/N=C/CCC1CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I15 compound treatment 67760.0 -95400.0 -2.55 63080.0 -88400.0 -2.39 -3.4969 -0.9995 3213398 CHDI2_000188 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I16 compound treatment 11120.0 -152000.0 -4.07 11200.0 -140000.0 -3.8 -5.5614 -0.9994 3213430 CHDI2_000189 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I17 compound treatment 142600.0 -20600.0 -0.55 159760.0 8270.0 0.22 -0.2306 -0.3883 3213402 CHDI2_000190 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I18 compound treatment 124280.0 -38900.0 -1.04 136280.0 -15200.0 -0.41 -1.0266 -0.9177 3213434 CHDI2_000191 ONC(=O)CCCCCCC(=O)N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I19 compound treatment 103640.0 -59500.0 -1.59 124720.0 -26800.0 -0.72 -1.6383 -0.9365 3213406 CHDI2_000192 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I20 mock treatment 167480.0 4310.0 0.12 179240.0 27800.0 0.75 0.6129 0.8063 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I21 compound treatment 45640.0 -118000.0 -3.14 49160.0 -102000.0 -2.77 -4.1818 -0.998 3214294 CHDI2_000193 Cc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I22 compound treatment 177040.0 13900.0 0.37 142400.0 -9090.0 -0.25 0.0885 0.1987 3214434 CHDI2_000194 ONC(=O)CCCCCC(=O)N/N=C/c1ccc[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I23 mock treatment 141520.0 -21600.0 -0.58 147360.0 -4130.0 -0.11 -0.4884 -0.8283 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 I24 mock treatment 151440.0 -11700.0 -0.31 152720.0 1230.0 0.03 -0.1982 -0.6283 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J01 compound treatment 174680.0 11500.0 0.31 154240.0 2750.0 0.07 0.2705 0.8536 3213376 CHDI2_000195 COc1cc(Cl)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J02 compound treatment 158000.0 -5170.0 -0.14 151760.0 273.0 0.01 -0.0925 -0.6683 3213414 CHDI2_000196 Oc1ccccc1NC(=O)CCCCCCC(=O)NN=C2CCCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J03 compound treatment 39400.0 -124000.0 -3.31 52080.0 -99400.0 -2.69 -4.2439 -0.9947 3213380 CHDI2_000197 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J04 compound treatment 187000.0 23800.0 0.64 153800.0 2310.0 0.06 0.4951 0.7728 3213416 CHDI2_000198 Oc1ccccc1NC(=O)CCCCCCC(=O)NN=C2CCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J05 compound treatment 135960.0 -27200.0 -0.73 134040.0 -17400.0 -0.47 -0.8486 -0.9781 3214571 CHDI2_000199 ONC(=O)CCCCCC(=O)NN=C1CCCCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J06 compound treatment 9840.0 -153000.0 -4.1 11760.0 -140000.0 -3.78 -5.5748 -0.9992 3214650 CHDI2_000200 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Oc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J07 compound treatment 89600.0 -73600.0 -1.97 171240.0 19800.0 0.53 -1.0133 -0.4969 3213384 CHDI2_000201 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J08 compound treatment 144720.0 -18400.0 -0.49 151280.0 -207.0 -0.01 -0.3528 -0.7151 3213418 CHDI2_000202 Oc1ccccc1NC(=O)CCCCCCC(=O)NN=C2CCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J09 compound treatment 13360.0 -150000.0 -4.01 13840.0 -138000.0 -3.73 -5.4684 -0.9993 3213388 CHDI2_000203 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J10 mock treatment 132040.0 -31100.0 -0.83 159840.0 8350.0 0.23 -0.4288 -0.497 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J11 compound treatment 127440.0 -35700.0 -0.96 131200.0 -20300.0 -0.55 -1.0641 -0.9654 3213392 CHDI2_000204 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3OCCc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J12 compound treatment 126640.0 -36500.0 -0.98 129160.0 -22300.0 -0.6 -1.1183 -0.9734 3213420 CHDI2_000205 COc1cc(Br)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J13 compound treatment 35040.0 -128000.0 -3.43 39320.0 -112000.0 -3.04 -4.5706 -0.9982 3213396 CHDI2_000206 Oc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J14 compound treatment 115840.0 -47300.0 -1.27 113000.0 -38500.0 -1.04 -1.6319 -0.9953 3213424 CHDI2_000207 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/CCC2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J15 compound treatment 31240.0 -132000.0 -3.53 24560.0 -127000.0 -3.44 -4.925 -0.9999 3213400 CHDI2_000208 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J16 compound treatment 137040.0 -26100.0 -0.7 150440.0 -1050.0 -0.03 -0.5142 -0.7352 3213428 CHDI2_000209 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J17 compound treatment 146120.0 -17000.0 -0.46 168280.0 16800.0 0.45 -9.0E-4 -0.0014 3213404 CHDI2_000210 Oc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J18 compound treatment 141520.0 -21600.0 -0.58 152120.0 633.0 0.02 -0.3973 -0.6859 3213432 CHDI2_000211 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J19 compound treatment 115480.0 -47700.0 -1.28 121320.0 -30200.0 -0.82 -1.4794 -0.9768 3213408 CHDI2_000212 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J20 mock treatment 134360.0 -28800.0 -0.77 151560.0 73.3 0.0 -0.5434 -0.7053 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J21 compound treatment 136800.0 -26400.0 -0.71 146800.0 -4690.0 -0.13 -0.5884 -0.8211 3214573 CHDI2_000213 ONC(=O)CCCCCC(=O)NN=C1CCCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J22 compound treatment 145200.0 -18000.0 -0.48 143440.0 -8050.0 -0.22 -0.4938 -0.936 3214654 CHDI2_000214 ONC(=O)CCCCCC(=O)N/N=C/c1cc[n+]([O-])cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J23 mock treatment 152840.0 -10300.0 -0.28 152920.0 1430.0 0.04 -0.1679 -0.6018 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 J24 mock treatment 187880.0 24700.0 0.66 149080.0 -2410.0 -0.07 0.4214 0.6343 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K01 compound treatment 64680.0 -98500.0 -2.63 82440.0 -69000.0 -1.87 -3.1845 -0.9859 3213436 CHDI2_000215 COc1cccc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K02 compound treatment 150720.0 -12400.0 -0.33 136440.0 -15000.0 -0.41 -0.5234 -0.995 3213474 CHDI2_000216 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K03 compound treatment 11560.0 -152000.0 -4.06 19440.0 -132000.0 -3.57 -5.3953 -0.998 3213440 CHDI2_000217 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K04 compound treatment 131080.0 -32100.0 -0.86 148600.0 -2890.0 -0.08 -0.6621 -0.7683 3213478 CHDI2_000218 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K05 compound treatment 129360.0 -33800.0 -0.9 133840.0 -17600.0 -0.48 -0.9772 -0.9555 3213444 CHDI2_000219 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K06 compound treatment 155640.0 -7530.0 -0.2 134640.0 -16800.0 -0.46 -0.4648 -0.9324 3213482 CHDI2_000220 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K07 compound treatment 133800.0 -29400.0 -0.79 149080.0 -2410.0 -0.07 -0.6015 -0.7631 3214298 CHDI2_000221 Cc1[nH]cnc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K08 compound treatment 16880.0 -146000.0 -3.91 21160.0 -130000.0 -3.53 -5.2617 -0.9987 3214438 CHDI2_000222 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)N2CCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K09 compound treatment 118680.0 -44500.0 -1.19 148640.0 -2850.0 -0.08 -0.8959 -0.7513 3213448 CHDI2_000223 CC1(C)COC(CCC/C=N/NC(=O)CCCCCCC(=O)NO)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K10 compound treatment 125160.0 -38000.0 -1.02 145960.0 -5530.0 -0.15 -0.8246 -0.8025 3213485 CHDI2_000224 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K11 compound treatment 142880.0 -20300.0 -0.54 162760.0 11300.0 0.31 -0.1679 -0.2697 3213452 CHDI2_000225 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K12 compound treatment 130840.0 -32300.0 -0.86 146880.0 -4610.0 -0.12 -0.6996 -0.8008 3213487 CHDI2_000226 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K13 compound treatment 8960.0 -154000.0 -4.12 11640.0 -140000.0 -3.79 -5.5938 -0.9991 3213456 CHDI2_000227 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)cs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K14 compound treatment 117480.0 -45700.0 -1.22 141960.0 -9530.0 -0.26 -1.0465 -0.8379 3213490 CHDI2_000228 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K15 compound treatment 13160.0 -150000.0 -4.01 17840.0 -134000.0 -3.62 -5.3957 -0.9987 3214342 CHDI2_000229 Cc1ccsc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K16 compound treatment 24560.0 -139000.0 -3.71 33080.0 -118000.0 -3.21 -4.8883 -0.9974 3214442 CHDI2_000230 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K17 compound treatment 126880.0 -36300.0 -0.97 133840.0 -17600.0 -0.48 -1.0241 -0.9467 3213460 CHDI2_000231 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K18 compound treatment 8360.0 -155000.0 -4.14 11120.0 -140000.0 -3.8 -5.6151 -0.9991 3213494 CHDI2_000232 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Oc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K19 compound treatment 9520.0 -154000.0 -4.11 11200.0 -140000.0 -3.8 -5.5916 -0.9992 3213464 CHDI2_000233 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc-2c(Cc3ccccc32)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K20 compound treatment 144440.0 -18700.0 -0.5 142120.0 -9370.0 -0.25 -0.5335 -0.9503 3213498 CHDI2_000234 ONC(=O)CCCCCCC(=O)N/N=C/c1cc[n+]([O-])cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K21 compound treatment 14560.0 -149000.0 -3.98 16400.0 -135000.0 -3.66 -5.3967 -0.9991 3213468 CHDI2_000235 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(F)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K22 compound treatment 8880.0 -154000.0 -4.13 9160.0 -142000.0 -3.85 -5.6428 -0.9994 3213502 CHDI2_000236 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2ccccc2n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K23 mock treatment 150600.0 -12600.0 -0.34 140200.0 -11300.0 -0.31 -0.4537 -0.9989 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 K24 mock treatment 149240.0 -13900.0 -0.37 150400.0 -1090.0 -0.03 -0.2842 -0.7606 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L01 compound treatment 171880.0 8710.0 0.23 169720.0 18200.0 0.49 0.5139 0.9413 3213438 CHDI2_000237 COc1cccc(OC)c1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L02 compound treatment 159240.0 -3930.0 -0.1 153200.0 1710.0 0.05 -0.0414 -0.3611 3213472 CHDI2_000238 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L03 compound treatment 146520.0 -16600.0 -0.45 139640.0 -11800.0 -0.32 -0.5416 -0.987 3213442 CHDI2_000239 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L04 compound treatment 159760.0 -3410.0 -0.09 144800.0 -6690.0 -0.18 -0.1924 -0.9495 3213476 CHDI2_000240 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L05 compound treatment 149760.0 -13400.0 -0.36 143640.0 -7850.0 -0.21 -0.4038 -0.9688 3213446 CHDI2_000241 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L06 compound treatment 158280.0 -4890.0 -0.13 155120.0 3630.0 0.1 -0.0229 -0.1397 3213480 CHDI2_000242 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L07 compound treatment 132240.0 -30900.0 -0.83 146080.0 -5410.0 -0.15 -0.6884 -0.8195 3214575 CHDI2_000243 ONC(=O)CCCCCC(=O)NN=C1CCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L08 compound treatment 10920.0 -152000.0 -4.07 14000.0 -137000.0 -3.72 -5.5115 -0.999 3214658 CHDI2_000244 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2ccccc2n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L09 compound treatment 157640.0 -5530.0 -0.15 166560.0 15100.0 0.41 0.184 0.424 3213450 CHDI2_000245 CC1(C)COC(CCC/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L10 compound treatment 137400.0 -25800.0 -0.69 148560.0 -2930.0 -0.08 -0.5434 -0.7832 3213484 CHDI2_000246 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L11 compound treatment 126920.0 -36200.0 -0.97 147960.0 -3530.0 -0.1 -0.7531 -0.773 3213454 CHDI2_000247 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCCC(=O)Nc3ccccc3O)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L12 compound treatment 135720.0 -27400.0 -0.73 141080.0 -10400.0 -0.28 -0.7183 -0.9135 3213486 CHDI2_000248 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L13 compound treatment 109000.0 -54200.0 -1.45 117440.0 -34000.0 -0.92 -1.6763 -0.9762 3213458 CHDI2_000249 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)cs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L14 compound treatment 138960.0 -24200.0 -0.65 144440.0 -7050.0 -0.19 -0.5927 -0.8781 3213488 CHDI2_000250 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L15 mock treatment 134640.0 -28500.0 -0.76 145600.0 -5890.0 -0.16 -0.6522 -0.8367 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L16 compound treatment 18080.0 -145000.0 -3.88 22280.0 -129000.0 -3.5 -5.2176 -0.9987 3214702 CHDI2_000251 Cc1ccccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L17 compound treatment 125920.0 -37200.0 -1.0 153760.0 2270.0 0.06 -0.6609 -0.6622 3213462 CHDI2_000252 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L18 compound treatment 137960.0 -25200.0 -0.67 142600.0 -8890.0 -0.24 -0.6469 -0.9036 3213492 CHDI2_000253 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L19 compound treatment 147200.0 -16000.0 -0.43 164800.0 13300.0 0.36 -0.0471 -0.0843 3213466 CHDI2_000254 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L20 compound treatment 132280.0 -30900.0 -0.83 164960.0 13500.0 0.36 -0.3263 -0.3613 3213496 CHDI2_000255 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L21 compound treatment 127600.0 -35600.0 -0.95 125320.0 -26200.0 -0.71 -1.1736 -0.9895 3213470 CHDI2_000256 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(F)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L22 compound treatment 98680.0 -64500.0 -1.72 106280.0 -45200.0 -1.22 -2.0851 -0.9859 3213500 CHDI2_000257 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3ccccc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L23 mock treatment 154120.0 -9050.0 -0.24 133880.0 -17600.0 -0.48 -0.5081 -0.9506 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 L24 mock treatment 176920.0 13800.0 0.37 136440.0 -15000.0 -0.41 -0.0279 -0.0508 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M01 compound treatment 28120.0 -135000.0 -3.61 71360.0 -80100.0 -2.17 -4.0882 -0.9702 3213504 CHDI2_000258 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M02 compound treatment 8600.0 -155000.0 -4.13 12840.0 -139000.0 -3.75 -5.5776 -0.9988 3213546 CHDI2_000259 Cc1ccccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M03 compound treatment 7560.0 -156000.0 -4.16 9760.0 -142000.0 -3.84 -5.6563 -0.9992 3213508 CHDI2_000260 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(F)c(Oc2ccccc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M04 compound treatment 25240.0 -138000.0 -3.69 66720.0 -84800.0 -2.29 -4.2315 -0.9739 3213550 CHDI2_000261 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M05 compound treatment 8760.0 -154000.0 -4.13 13160.0 -138000.0 -3.74 -5.5685 -0.9988 3213512 CHDI2_000262 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(F)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M06 compound treatment 127760.0 -35400.0 -0.95 164440.0 13000.0 0.35 -0.4217 -0.4176 3213554 CHDI2_000263 ONC(=O)CCCCCCC(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M07 compound treatment 150440.0 -12700.0 -0.34 149800.0 -1690.0 -0.05 -0.273 -0.7948 3213516 CHDI2_000264 ONC(=O)CCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M08 compound treatment 130960.0 -32200.0 -0.86 131000.0 -20500.0 -0.55 -1.0013 -0.9773 3213557 CHDI2_000265 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M09 compound treatment 8480.0 -155000.0 -4.14 11760.0 -140000.0 -3.78 -5.6006 -0.999 3214350 CHDI2_000266 ONC(=O)CCCCCC(=O)N/N=C/c1cccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M10 compound treatment 44600.0 -119000.0 -3.17 70720.0 -80800.0 -2.19 -3.7887 -0.9835 3214450 CHDI2_000267 ONC(=O)CCCCCC(=O)N/N=C/c1nccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M11 compound treatment 7520.0 -156000.0 -4.16 11560.0 -140000.0 -3.79 -5.6226 -0.9989 3213520 CHDI2_000268 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M12 compound treatment 28240.0 -135000.0 -3.61 30840.0 -121000.0 -3.27 -4.8616 -0.9988 3213560 CHDI2_000269 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M13 compound treatment 6160.0 -157000.0 -4.2 8160.0 -143000.0 -3.88 -5.7134 -0.9992 3214358 CHDI2_000270 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2ccccc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M14 compound treatment 21080.0 -142000.0 -3.8 26160.0 -125000.0 -3.39 -5.0866 -0.9984 3214492 CHDI2_000271 ONC(=O)CCCCCC(=O)N/N=C/c1cccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M15 compound treatment 116760.0 -46400.0 -1.24 145120.0 -6370.0 -0.17 -0.9996 -0.7976 3213524 CHDI2_000272 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(c1)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M16 compound treatment 8200.0 -155000.0 -4.15 11760.0 -140000.0 -3.78 -5.6059 -0.999 3213564 CHDI2_000273 CCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)NO)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M17 compound treatment 26240.0 -137000.0 -3.66 31640.0 -120000.0 -3.24 -4.8841 -0.9982 3213528 CHDI2_000274 ONC(=O)CCCCCCC(=O)N/N=C/c1ccco1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M18 compound treatment 7000.0 -156000.0 -4.18 9720.0 -142000.0 -3.84 -5.6676 -0.9991 3213568 CHDI2_000275 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(I)cc(I)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M19 compound treatment 35040.0 -128000.0 -3.43 41080.0 -110000.0 -2.99 -4.5369 -0.9977 3213532 CHDI2_000276 ONC(=O)CCCCCCC(=O)N/N=C/c1ccoc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M20 compound treatment 34360.0 -129000.0 -3.45 41080.0 -110000.0 -2.99 -4.5498 -0.9975 3213572 CHDI2_000277 CN(C)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M21 compound treatment 19720.0 -143000.0 -3.84 25560.0 -126000.0 -3.41 -5.1238 -0.9983 3213536 CHDI2_000278 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M22 compound treatment 8360.0 -155000.0 -4.14 9640.0 -142000.0 -3.84 -5.6434 -0.9993 3213576 CHDI2_000279 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M23 mock treatment 164920.0 1750.0 0.05 152080.0 593.0 0.02 0.0445 0.898 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 M24 mock treatment 166000.0 2830.0 0.08 145240.0 -6250.0 -0.17 -0.066 -0.3559 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N01 compound treatment 194120.0 31000.0 0.83 156800.0 5310.0 0.14 0.6872 0.8177 3213506 CHDI2_000280 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N02 compound treatment 134160.0 -29000.0 -0.78 152560.0 1070.0 0.03 -0.5281 -0.6801 3213544 CHDI2_000281 Cc1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N03 compound treatment 159960.0 -3210.0 -0.09 182240.0 30800.0 0.83 0.5281 0.6309 3213510 CHDI2_000282 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N04 compound treatment 151040.0 -12100.0 -0.32 145680.0 -5810.0 -0.16 -0.3405 -0.9447 3213548 CHDI2_000283 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N05 compound treatment 113640.0 -49500.0 -1.32 126360.0 -25100.0 -0.68 -1.4177 -0.952 3213514 CHDI2_000284 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(F)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N06 compound treatment 140480.0 -22700.0 -0.61 170520.0 19000.0 0.52 -0.0647 -0.0813 3213552 CHDI2_000285 O[C@@H](/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N07 compound treatment 127640.0 -35500.0 -0.95 165880.0 14400.0 0.39 -0.3964 -0.386 3213518 CHDI2_000286 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N08 compound treatment 130480.0 -32700.0 -0.87 185600.0 34100.0 0.92 0.0348 0.0274 3213556 CHDI2_000287 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N09 compound treatment 111280.0 -51900.0 -1.39 143040.0 -8450.0 -0.23 -1.1431 -0.8127 3214582 CHDI2_000288 ONC(=O)CCCCCC(=O)N/N=C/CCC1CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N10 compound treatment 113560.0 -49600.0 -1.33 178720.0 27200.0 0.74 -0.4169 -0.2747 3214710 CHDI2_000289 ONC(=O)CCCCCC(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N11 compound treatment 66280.0 -96900.0 -2.59 100120.0 -51400.0 -1.39 -2.8158 -0.9574 3213522 CHDI2_000290 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N12 compound treatment 110200.0 -53000.0 -1.42 129240.0 -22200.0 -0.6 -1.4277 -0.9274 3213558 CHDI2_000291 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N13 compound treatment 6080.0 -157000.0 -4.2 8400.0 -143000.0 -3.87 -5.7103 -0.9992 3214586 CHDI2_000292 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N14 compound treatment 127600.0 -35600.0 -0.95 132280.0 -19200.0 -0.52 -1.0404 -0.9596 3214713 CHDI2_000293 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N15 compound treatment 114360.0 -48800.0 -1.31 133480.0 -18000.0 -0.49 -1.2678 -0.9098 3213526 CHDI2_000294 OB(O)c1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N16 compound treatment 150080.0 -13100.0 -0.35 159560.0 8070.0 0.22 -0.093 -0.2253 3213562 CHDI2_000295 CCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N17 compound treatment 127840.0 -35300.0 -0.94 141120.0 -10400.0 -0.28 -0.8666 -0.8792 3213530 CHDI2_000296 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccco2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N18 compound treatment 7680.0 -155000.0 -4.16 11480.0 -140000.0 -3.79 -5.6211 -0.9989 3213566 CHDI2_000297 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N19 compound treatment 136440.0 -26700.0 -0.71 142520.0 -8970.0 -0.24 -0.6771 -0.8969 3213534 CHDI2_000298 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccoc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N20 compound treatment 170760.0 7590.0 0.2 147240.0 -4250.0 -0.11 0.0624 0.2671 3213570 CHDI2_000299 CN(C)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N21 compound treatment 122120.0 -41000.0 -1.1 116320.0 -35200.0 -0.95 -1.4495 -0.9975 3213538 CHDI2_000300 Oc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N22 compound treatment 142600.0 -20600.0 -0.55 164080.0 12600.0 0.34 -0.1479 -0.2285 3213574 CHDI2_000301 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCCC(=O)Nc4ccccc4O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N23 mock treatment 155560.0 -7610.0 -0.2 139720.0 -11800.0 -0.32 -0.3691 -0.9765 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 N24 mock treatment 168880.0 5710.0 0.15 133040.0 -18400.0 -0.5 -0.245 -0.4692 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O01 compound treatment 19120.0 -144000.0 -3.85 38720.0 -113000.0 -3.05 -4.8832 -0.9934 3213582 CHDI2_000302 OCCOc1ccccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O02 compound treatment 152120.0 -11000.0 -0.3 139160.0 -12300.0 -0.33 -0.4449 -0.9982 3213628 CHDI2_000303 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(o1)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O03 compound treatment 11840.0 -151000.0 -4.05 35600.0 -116000.0 -3.14 -5.0806 -0.9921 3213586 CHDI2_000304 OCCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O04 compound treatment 11240.0 -152000.0 -4.06 18320.0 -133000.0 -3.61 -5.4228 -0.9982 3213632 CHDI2_000305 Cn1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O05 compound treatment 15440.0 -148000.0 -3.95 30560.0 -121000.0 -3.27 -5.109 -0.9956 3213590 CHDI2_000306 OCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O06 compound treatment 5000.0 -158000.0 -4.23 7720.0 -144000.0 -3.89 -5.7437 -0.9991 3213636 CHDI2_000307 ONC(=O)CCCCCCC(=O)N/N=C/c1cn(Cc2ccccc2)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O07 compound treatment 5920.0 -157000.0 -4.21 11720.0 -140000.0 -3.78 -5.6498 -0.9986 3213594 CHDI2_000308 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O08 compound treatment 9560.0 -154000.0 -4.11 17480.0 -134000.0 -3.63 -5.4706 -0.9981 3213640 CHDI2_000309 ONC(=O)CCCCCCC(=O)N/N=C/C1=CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O09 compound treatment 7000.0 -156000.0 -4.18 10440.0 -141000.0 -3.82 -5.6538 -0.999 3213598 CHDI2_000310 COc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O10 compound treatment 103240.0 -59900.0 -1.6 130840.0 -20600.0 -0.56 -1.5287 -0.9005 3213643 CHDI2_000311 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O11 compound treatment 14080.0 -149000.0 -3.99 27000.0 -124000.0 -3.37 -5.2029 -0.9965 3214290 CHDI2_000312 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O12 compound treatment 6400.0 -157000.0 -4.19 8080.0 -143000.0 -3.88 -5.7104 -0.9993 3214496 CHDI2_000313 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O13 compound treatment 6440.0 -157000.0 -4.19 9520.0 -142000.0 -3.84 -5.682 -0.9991 3213602 CHDI2_000314 COc1cc(/C=C/C=N/NC(=O)CCCCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O14 compound treatment 114680.0 -48500.0 -1.3 121880.0 -29600.0 -0.8 -1.4838 -0.9732 3213646 CHDI2_000315 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O15 compound treatment 7640.0 -156000.0 -4.16 10120.0 -141000.0 -3.83 -5.6478 -0.9991 3213606 CHDI2_000316 Cc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O16 compound treatment 119560.0 -43600.0 -1.17 144680.0 -6810.0 -0.18 -0.9551 -0.8088 3213650 CHDI2_000317 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O17 compound treatment 60880.0 -102000.0 -2.74 95440.0 -56000.0 -1.52 -3.0076 -0.9613 3213610 CHDI2_000318 OCc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O18 compound treatment 115120.0 -48000.0 -1.29 139040.0 -12400.0 -0.34 -1.147 -0.8633 3213654 CHDI2_000319 C/C(=N\NC(=O)CCCCCCC(=O)NO)/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O19 compound treatment 6280.0 -157000.0 -4.2 8320.0 -143000.0 -3.88 -5.708 -0.9992 3213614 CHDI2_000320 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2ccccc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O20 compound treatment 96000.0 -67200.0 -1.8 97640.0 -53800.0 -1.46 -2.3012 -0.9946 3213658 CHDI2_000321 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O21 compound treatment 5960.0 -157000.0 -4.21 7800.0 -144000.0 -3.89 -5.724 -0.9992 3213618 CHDI2_000322 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(o1)c2cccc(Cl)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O22 compound treatment 22040.0 -141000.0 -3.77 61800.0 -89700.0 -2.43 -4.3862 -0.9772 3213662 CHDI2_000323 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O23 mock treatment 138760.0 -24400.0 -0.65 136240.0 -15200.0 -0.41 -0.7535 -0.9756 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 O24 mock treatment 182080.0 18900.0 0.51 143200.0 -8290.0 -0.22 0.1991 0.3598 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P01 compound treatment 185560.0 22400.0 0.6 156040.0 4550.0 0.12 0.5107 0.8351 3213584 CHDI2_000324 OCCOc1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P02 compound treatment 164080.0 915.0 0.02 139880.0 -11600.0 -0.31 -0.2049 -0.6501 3213626 CHDI2_000325 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P03 compound treatment 129840.0 -33300.0 -0.89 135480.0 -16000.0 -0.43 -0.9367 -0.9451 3213588 CHDI2_000326 OCCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P04 compound treatment 104960.0 -58200.0 -1.56 118400.0 -33100.0 -0.9 -1.7343 -0.9655 3213630 CHDI2_000327 Cn1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P05 compound treatment 118440.0 -44700.0 -1.2 152880.0 1390.0 0.04 -0.8193 -0.6845 3213592 CHDI2_000328 OCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P06 compound treatment 38280.0 -125000.0 -3.34 47600.0 -104000.0 -2.81 -4.3508 -0.9963 3213634 CHDI2_000329 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P07 compound treatment 104760.0 -58400.0 -1.56 113880.0 -37600.0 -1.02 -1.8246 -0.9785 3213596 CHDI2_000330 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P08 compound treatment 139800.0 -23400.0 -0.62 176000.0 24500.0 0.66 0.0273 0.03 3213638 CHDI2_000331 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C2=CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P09 compound treatment 82840.0 -80300.0 -2.15 103920.0 -47600.0 -1.29 -2.4299 -0.97 3213600 CHDI2_000332 COc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P10 compound treatment 121520.0 -41600.0 -1.11 163520.0 12000.0 0.33 -0.5573 -0.4802 3213642 CHDI2_000333 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P11 compound treatment 82360.0 -80800.0 -2.16 117680.0 -33800.0 -0.92 -2.1755 -0.9269 3214590 CHDI2_000334 ONC(=O)CCCCCC(=O)N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P12 compound treatment 55960.0 -107000.0 -2.87 95600.0 -55900.0 -1.51 -3.0976 -0.9554 3214716 CHDI2_000335 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P13 compound treatment 89600.0 -73600.0 -1.97 117920.0 -33600.0 -0.91 -2.034 -0.9384 3213604 CHDI2_000336 COc1cc(/C=C/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P14 compound treatment 131200.0 -32000.0 -0.86 146440.0 -5050.0 -0.14 -0.7012 -0.8098 3213644 CHDI2_000337 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P15 compound treatment 70760.0 -92400.0 -2.47 87920.0 -63600.0 -1.72 -2.9646 -0.9843 3213608 CHDI2_000338 Cc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P16 compound treatment 121480.0 -41700.0 -1.12 152080.0 593.0 0.02 -0.7771 -0.6968 3213648 CHDI2_000339 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P17 compound treatment 114800.0 -48400.0 -1.29 152600.0 1110.0 0.03 -0.8935 -0.6904 3213612 CHDI2_000340 OCc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P18 compound treatment 125600.0 -37600.0 -1.0 136760.0 -14700.0 -0.4 -0.9924 -0.918 3213652 CHDI2_000341 C/C(=N\NC(=O)CCCCCCC(=O)Nc1ccccc1O)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P19 compound treatment 32520.0 -131000.0 -3.49 22240.0 -129000.0 -3.5 -4.9452 -1.0 3213616 CHDI2_000342 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3ccccc3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P20 compound treatment 103080.0 -60100.0 -1.61 114600.0 -36900.0 -1.0 -1.8426 -0.9738 3213656 CHDI2_000343 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P21 compound treatment 39320.0 -124000.0 -3.31 74560.0 -76900.0 -2.08 -3.8151 -0.975 3213620 CHDI2_000344 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P22 compound treatment 128440.0 -34700.0 -0.93 122720.0 -28800.0 -0.78 -1.2075 -0.9962 3213660 CHDI2_000345 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P23 mock treatment 163160.0 -5.41 0.0 135800.0 -15700.0 -0.42 -0.3004 -0.7073 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2403 P24 mock treatment 172600.0 9430.0 0.25 144040.0 -7450.0 -0.2 0.0359 0.1111 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A01 compound treatment 204560.0 52900.0 1.41 194400.0 54400.0 1.47 2.0413 0.9998 3214214 CHDI2_000346 NNC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A02 compound treatment 223280.0 71600.0 1.92 192360.0 52300.0 1.42 2.3563 0.989 3214215 CHDI2_000347 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A03 compound treatment 24160.0 -128000.0 -3.41 21920.0 -118000.0 -3.2 -4.6727 -0.9995 3214216 CHDI2_000348 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A04 compound treatment 160280.0 8620.0 0.23 124720.0 -15300.0 -0.41 -0.1302 -0.2744 3214218 CHDI2_000349 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A05 compound treatment 30200.0 -121000.0 -3.25 18000.0 -122000.0 -3.3 -4.6335 -1.0 3214220 CHDI2_000350 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A06 compound treatment 187640.0 36000.0 0.96 149000.0 8970.0 0.24 0.8521 0.8586 3214222 CHDI2_000351 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A07 compound treatment 40640.0 -111000.0 -2.97 13920.0 -126000.0 -3.41 -4.5141 -0.9976 3214224 CHDI2_000352 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A08 compound treatment 195440.0 43800.0 1.17 145400.0 5370.0 0.15 0.9307 0.7888 3214226 CHDI2_000353 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A09 compound treatment 35640.0 -116000.0 -3.1 18320.0 -122000.0 -3.3 -4.5245 -0.9996 3214228 CHDI2_000354 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2OCCOc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A10 compound treatment 168600.0 16900.0 0.45 124080.0 -16000.0 -0.43 0.015 0.0239 3214230 CHDI2_000355 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3OCCOc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A11 compound treatment 195200.0 43500.0 1.16 139280.0 -754.0 -0.02 0.809 0.6946 3214232 CHDI2_000356 ONC(=O)CCCCCC(=O)N/N=C/COCc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A12 compound treatment 220880.0 69200.0 1.85 185720.0 45700.0 1.24 2.1838 0.9808 3214234 CHDI2_000357 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/COCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A13 compound treatment 36160.0 -116000.0 -3.09 19960.0 -120000.0 -3.25 -4.4832 -0.9997 3214720 CHDI2_000358 CCOc1cccc(/C=N/NC(=O)CCCCCC(=O)NO)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A14 compound treatment 8000.0 -144000.0 -3.84 7560.0 -132000.0 -3.59 -5.2532 -0.9994 3553354 CHDI2_000359 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A15 compound treatment 5160.0 -147000.0 -3.92 3560.0 -136000.0 -3.69 -5.3835 -0.9996 3214236 CHDI2_000360 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A16 compound treatment 119800.0 -31900.0 -0.85 86280.0 -53800.0 -1.46 -1.6317 -0.9675 3214238 CHDI2_000361 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A17 compound treatment 8640.0 -143000.0 -3.83 4240.0 -136000.0 -3.68 -5.3047 -0.9998 3214240 CHDI2_000362 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A18 compound treatment 29240.0 -122000.0 -3.27 15440.0 -125000.0 -3.37 -4.7006 -0.9999 3214242 CHDI2_000363 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A19 compound treatment 54240.0 -97400.0 -2.61 32960.0 -107000.0 -2.9 -3.8924 -0.9986 3214244 CHDI2_000364 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A20 compound treatment 197080.0 45400.0 1.21 182160.0 42100.0 1.14 1.6655 0.9995 3214246 CHDI2_000365 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A21 compound treatment 9440.0 -142000.0 -3.8 6680.0 -133000.0 -3.61 -5.2428 -0.9997 3214248 CHDI2_000366 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Br)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A22 compound treatment 117760.0 -33900.0 -0.91 100040.0 -40000.0 -1.08 -1.4068 -0.9961 3214250 CHDI2_000367 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Br)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A23 mock treatment 211280.0 59600.0 1.59 198240.0 58200.0 1.58 2.2419 1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 A24 mock treatment 210800.0 59100.0 1.58 181880.0 41800.0 1.13 1.9196 0.9866 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B01 compound treatment 11840.0 -140000.0 -3.74 7880.0 -132000.0 -3.58 -5.1745 -0.9998 3214256 CHDI2_000368 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B02 compound treatment 216920.0 65300.0 1.75 158200.0 18200.0 0.49 1.5821 0.8724 3214824 CHDI2_000369 NNC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B03 compound treatment 142120.0 -9540.0 -0.26 96000.0 -44000.0 -1.19 -1.0234 -0.8395 3214260 CHDI2_000370 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B04 compound treatment 65800.0 -85900.0 -2.3 41840.0 -98200.0 -2.66 -3.5038 -0.9973 3214826 CHDI2_000371 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B05 compound treatment 174240.0 22600.0 0.6 114240.0 -25800.0 -0.7 -0.0667 -0.0723 3214264 CHDI2_000372 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B06 compound treatment 172680.0 21000.0 0.56 123280.0 -16800.0 -0.45 0.0768 0.1063 3214830 CHDI2_000373 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B07 compound treatment 147160.0 -4500.0 -0.12 114680.0 -25400.0 -0.69 -0.5705 -0.8187 3214268 CHDI2_000374 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B08 compound treatment 142920.0 -8740.0 -0.23 109080.0 -31000.0 -0.84 -0.7579 -0.8712 3214834 CHDI2_000375 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B09 compound treatment 152440.0 777.0 0.02 99720.0 -40300.0 -1.09 -0.757 -0.6935 3214272 CHDI2_000376 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B10 compound treatment 151240.0 -423.0 -0.01 110880.0 -29200.0 -0.79 -0.5661 -0.7172 3214838 CHDI2_000377 ONC(=O)CCCCC(=O)N/N=C/c1ccc2OCCOc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B11 compound treatment 88360.0 -63300.0 -1.69 46680.0 -93400.0 -2.53 -2.9844 -0.981 3214276 CHDI2_000378 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2c[nH]c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B12 compound treatment 158760.0 7100.0 0.19 133760.0 -6270.0 -0.17 0.0141 0.0555 3214842 CHDI2_000379 ONC(=O)CCCCC(=O)N/N=C/COCc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B13 compound treatment 165280.0 13600.0 0.36 150880.0 10800.0 0.29 0.4652 0.9943 3553415 CHDI2_000380 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B14 compound treatment 143520.0 -8140.0 -0.22 129280.0 -10800.0 -0.29 -0.3599 -0.9898 3553478 CHDI2_000381 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c(O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B15 compound treatment 45720.0 -106000.0 -2.83 26960.0 -113000.0 -3.06 -4.1684 -0.9993 3214280 CHDI2_000382 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(I)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B16 compound treatment 17840.0 -134000.0 -3.58 6240.0 -134000.0 -3.62 -5.0924 -1.0 3214846 CHDI2_000383 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B17 compound treatment 178720.0 27100.0 0.72 134640.0 -5390.0 -0.15 0.4085 0.5533 3214284 CHDI2_000384 C/C=C(/C)\C=N\NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B18 compound treatment 14480.0 -137000.0 -3.67 4880.0 -135000.0 -3.66 -5.182 -1.0 3214850 CHDI2_000385 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B19 compound treatment 120560.0 -31100.0 -0.83 69720.0 -70300.0 -1.9 -1.9343 -0.9311 3214360 CHDI2_000386 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B20 compound treatment 148920.0 -2740.0 -0.07 113840.0 -26200.0 -0.71 -0.5533 -0.7761 3214854 CHDI2_000387 ONC(=O)CCCCC(=O)N/N=C/c1cccc(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B21 compound treatment 147720.0 -3940.0 -0.11 114880.0 -25200.0 -0.68 -0.5561 -0.807 3214292 CHDI2_000388 Cc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B22 compound treatment 148680.0 -2980.0 -0.08 122000.0 -18000.0 -0.49 -0.4016 -0.8119 3214858 CHDI2_000389 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Br)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B23 mock treatment 209720.0 58100.0 1.55 138800.0 -1230.0 -0.03 1.0745 0.6917 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 B24 mock treatment 209560.0 57900.0 1.55 189040.0 49000.0 1.33 2.0332 0.997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C01 compound treatment 76360.0 -75300.0 -2.01 69400.0 -70600.0 -1.91 -2.7764 -0.9997 3214300 CHDI2_000390 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Br)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C02 compound treatment 164680.0 13000.0 0.35 114920.0 -25100.0 -0.68 -0.2345 -0.307 3214302 CHDI2_000391 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Br)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C03 compound treatment 30960.0 -121000.0 -3.23 24040.0 -116000.0 -3.14 -4.5035 -0.9999 3214304 CHDI2_000392 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C04 compound treatment 22480.0 -129000.0 -3.46 11200.0 -129000.0 -3.49 -4.9097 -1.0 3214306 CHDI2_000393 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C05 compound treatment 22920.0 -129000.0 -3.44 17520.0 -123000.0 -3.32 -4.7804 -0.9998 3214308 CHDI2_000394 ONC(=O)CCCCCC(=O)N/N=C/c1cc(O)ccc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C06 compound treatment 23760.0 -128000.0 -3.42 14920.0 -125000.0 -3.39 -4.8143 -1.0 3214310 CHDI2_000395 Oc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C07 compound treatment 7680.0 -144000.0 -3.85 4240.0 -136000.0 -3.68 -5.3228 -0.9997 3214312 CHDI2_000396 COc1cc(Br)cc(/C=N/NC(=O)CCCCCC(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C08 compound treatment 43520.0 -108000.0 -2.89 33920.0 -106000.0 -2.87 -4.0768 -1.0 3214314 CHDI2_000397 COc1cc(Br)cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C09 compound treatment 11080.0 -141000.0 -3.76 6200.0 -134000.0 -3.62 -5.221 -0.9998 3214316 CHDI2_000398 COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C10 compound treatment 28600.0 -123000.0 -3.29 15160.0 -125000.0 -3.38 -4.7181 -0.9999 3214318 CHDI2_000399 COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C11 compound treatment 11440.0 -140000.0 -3.75 7800.0 -132000.0 -3.58 -5.1836 -0.9997 3214724 CHDI2_000400 ONC(=O)CCCCCC(=O)N/N=C/c1cc(I)cc(I)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C12 compound treatment 162360.0 10700.0 0.29 140120.0 86.5 0.0 0.204 0.7129 3553358 CHDI2_000401 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C13 compound treatment 12320.0 -139000.0 -3.73 9720.0 -130000.0 -3.53 -5.1302 -0.9996 3214320 CHDI2_000402 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C14 compound treatment 27680.0 -124000.0 -3.32 24600.0 -115000.0 -3.13 -4.5548 -0.9996 3214322 CHDI2_000403 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C15 compound treatment 33600.0 -118000.0 -3.16 25600.0 -114000.0 -3.1 -4.4237 -1.0 3214728 CHDI2_000404 CN(C)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C16 compound treatment 149200.0 -2460.0 -0.07 118520.0 -21500.0 -0.58 -0.4584 -0.7821 3553362 CHDI2_000405 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C17 compound treatment 12840.0 -139000.0 -3.71 6840.0 -133000.0 -3.61 -5.1755 -0.9999 3214324 CHDI2_000406 ONC(=O)CCCCCC(=O)N/N=C/c1cc2OCOc2cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C18 compound treatment 36720.0 -115000.0 -3.07 19520.0 -121000.0 -3.26 -4.4811 -0.9996 3214326 CHDI2_000407 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C19 compound treatment 51480.0 -100000.0 -2.68 28920.0 -111000.0 -3.01 -4.0219 -0.9983 3214328 CHDI2_000408 ONC(=O)CCCCCC(=O)N/N=C/c1cccnc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C20 compound treatment 85080.0 -66600.0 -1.78 49880.0 -90200.0 -2.44 -2.9852 -0.988 3214330 CHDI2_000409 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccnc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C21 compound treatment 38760.0 -113000.0 -3.02 22640.0 -117000.0 -3.18 -4.3828 -0.9997 3214332 CHDI2_000410 ONC(=O)CCCCCC(=O)N/N=C/c1ccncc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C22 compound treatment 68160.0 -83500.0 -2.23 43120.0 -96900.0 -2.62 -3.4346 -0.9968 3214334 CHDI2_000411 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccncc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C23 mock treatment 143200.0 -8460.0 -0.23 139600.0 -434.0 -0.01 -0.1684 -0.7428 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 C24 mock treatment 196920.0 45300.0 1.21 136960.0 -3070.0 -0.08 0.7972 0.657 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D01 compound treatment 107160.0 -44500.0 -1.19 83640.0 -56400.0 -1.53 -1.9213 -0.9924 3214340 CHDI2_000412 Cc1ccsc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D02 compound treatment 134280.0 -17400.0 -0.46 121680.0 -18400.0 -0.5 -0.6801 -0.9995 3214910 CHDI2_000413 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Br)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D03 compound treatment 161360.0 9700.0 0.26 136880.0 -3150.0 -0.09 0.123 0.4506 3214344 CHDI2_000414 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCC(=O)Nc3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D04 compound treatment 30080.0 -122000.0 -3.25 19440.0 -121000.0 -3.26 -4.6082 -1.0 3214914 CHDI2_000415 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D05 compound treatment 13640.0 -138000.0 -3.69 9200.0 -131000.0 -3.54 -5.1152 -0.9998 3214348 CHDI2_000416 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D06 compound treatment 32080.0 -120000.0 -3.2 19640.0 -120000.0 -3.26 -4.5665 -1.0 3214918 CHDI2_000417 ONC(=O)CCCCC(=O)N/N=C/c1cc(O)ccc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D07 compound treatment 16760.0 -135000.0 -3.61 10720.0 -129000.0 -3.5 -5.0271 -0.9999 3214356 CHDI2_000418 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3ccccc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D08 compound treatment 32800.0 -119000.0 -3.18 16400.0 -124000.0 -3.35 -4.6149 -0.9997 3214922 CHDI2_000419 COc1cc(Br)cc(/C=N/NC(=O)CCCCC(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D09 compound treatment 134480.0 -17200.0 -0.46 109240.0 -30800.0 -0.83 -0.9145 -0.9606 3214288 CHDI2_000420 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D10 compound treatment 11520.0 -140000.0 -3.75 8360.0 -132000.0 -3.56 -5.1713 -0.9997 3214926 CHDI2_000421 COc1ccc(Br)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D11 compound treatment 211640.0 60000.0 1.6 152840.0 12800.0 0.35 1.3796 0.8405 3553419 CHDI2_000422 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D12 compound treatment 126320.0 -25300.0 -0.68 121520.0 -18500.0 -0.5 -0.8337 -0.989 3553482 CHDI2_000423 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c(O)cc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D13 compound treatment 140440.0 -11200.0 -0.3 127600.0 -12400.0 -0.34 -0.4503 -0.9984 3214352 CHDI2_000424 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D14 compound treatment 17040.0 -135000.0 -3.6 14040.0 -126000.0 -3.41 -4.9582 -0.9996 3214930 CHDI2_000425 COc1ccc(Br)cc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D15 compound treatment 146400.0 -5260.0 -0.14 120960.0 -19100.0 -0.52 -0.4647 -0.8682 3553423 CHDI2_000426 ONC(=O)c1cccc(c1)C(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D16 compound treatment 163440.0 11800.0 0.32 135240.0 -4790.0 -0.13 0.131 0.3845 3553485 CHDI2_000427 COc1cc(OC)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D17 compound treatment 163880.0 12200.0 0.33 145280.0 5250.0 0.14 0.3315 0.9304 3214364 CHDI2_000428 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D18 compound treatment 14400.0 -137000.0 -3.67 9200.0 -131000.0 -3.54 -5.1008 -0.9998 3214934 CHDI2_000429 ONC(=O)CCCCC(=O)N/N=C/c1cc2OCOc2cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D19 compound treatment 213320.0 61700.0 1.65 158880.0 18800.0 0.51 1.527 0.8845 3214368 CHDI2_000430 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D20 compound treatment 109520.0 -42100.0 -1.13 79760.0 -60300.0 -1.63 -1.9509 -0.9837 3214938 CHDI2_000431 ONC(=O)CCCCC(=O)N/N=C/c1cccnc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D21 compound treatment 122320.0 -29300.0 -0.78 110280.0 -29800.0 -0.81 -1.1246 -0.9999 3214372 CHDI2_000432 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D22 compound treatment 78480.0 -73200.0 -1.96 50720.0 -89300.0 -2.42 -3.0939 -0.9945 3214942 CHDI2_000433 ONC(=O)CCCCC(=O)N/N=C/c1ccncc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D23 mock treatment 169320.0 17700.0 0.47 163440.0 23400.0 0.63 0.782 0.9895 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 D24 mock treatment 150400.0 -1260.0 -0.03 152280.0 12200.0 0.33 0.2105 0.6318 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E01 compound treatment 6920.0 -145000.0 -3.87 6080.0 -134000.0 -3.63 -5.302 -0.9995 3214732 CHDI2_000434 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E02 compound treatment 182680.0 31000.0 0.83 129960.0 -10100.0 -0.27 0.3938 0.4509 3553366 CHDI2_000435 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(O)ccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E03 compound treatment 13720.0 -138000.0 -3.69 10400.0 -130000.0 -3.51 -5.0907 -0.9997 3214380 CHDI2_000436 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Br)s1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E04 compound treatment 91560.0 -60100.0 -1.61 69000.0 -71000.0 -1.92 -2.4966 -0.996 3214382 CHDI2_000437 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Br)s2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E05 compound treatment 71240.0 -80400.0 -2.15 58240.0 -81800.0 -2.21 -3.0869 -0.9999 3214384 CHDI2_000438 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E06 compound treatment 34120.0 -118000.0 -3.14 27200.0 -113000.0 -3.05 -4.3832 -0.9999 3214386 CHDI2_000439 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E07 compound treatment 6160.0 -146000.0 -3.89 4960.0 -135000.0 -3.66 -5.3378 -0.9995 3214388 CHDI2_000440 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E08 compound treatment 11240.0 -140000.0 -3.76 6960.0 -133000.0 -3.6 -5.2034 -0.9998 3214390 CHDI2_000441 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E09 compound treatment 9720.0 -142000.0 -3.8 6920.0 -133000.0 -3.6 -5.233 -0.9997 3214736 CHDI2_000442 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(c(F)c1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E10 compound treatment 155000.0 3340.0 0.09 134720.0 -5310.0 -0.14 -0.0386 -0.228 3553369 CHDI2_000443 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E11 compound treatment 107400.0 -44300.0 -1.18 90680.0 -49400.0 -1.34 -1.782 -0.9982 3214392 CHDI2_000444 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E12 compound treatment 167040.0 15400.0 0.41 131120.0 -8910.0 -0.24 0.1202 0.2521 3214394 CHDI2_000445 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E13 compound treatment 110560.0 -41100.0 -1.1 104000.0 -36000.0 -0.98 -1.4672 -0.9982 3214396 CHDI2_000446 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E14 compound treatment 131000.0 -20700.0 -0.55 130400.0 -9630.0 -0.26 -0.5752 -0.9412 3214398 CHDI2_000447 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E15 compound treatment 36440.0 -115000.0 -3.08 28880.0 -111000.0 -3.01 -4.3072 -0.9999 3214400 CHDI2_000448 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E16 compound treatment 119920.0 -31700.0 -0.85 104400.0 -35600.0 -0.96 -1.2825 -0.998 3214402 CHDI2_000449 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E17 compound treatment 157320.0 5660.0 0.15 130560.0 -9470.0 -0.26 -0.0744 -0.2497 3214784 CHDI2_000450 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(o1)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E18 compound treatment 139600.0 -12100.0 -0.32 124960.0 -15100.0 -0.41 -0.5167 -0.9932 3553372 CHDI2_000451 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c[nH]c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E19 compound treatment 145200.0 -6460.0 -0.17 122680.0 -17400.0 -0.47 -0.4544 -0.9078 3214404 CHDI2_000452 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E20 compound treatment 148360.0 -3300.0 -0.09 128240.0 -11800.0 -0.32 -0.2882 -0.8701 3214406 CHDI2_000453 OC(=O)c1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E21 compound treatment 149400.0 -2260.0 -0.06 128960.0 -11100.0 -0.3 -0.2548 -0.8331 3214408 CHDI2_000454 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E22 compound treatment 144560.0 -7100.0 -0.19 128480.0 -11600.0 -0.31 -0.3555 -0.9714 3214410 CHDI2_000455 OC(=O)c1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E23 mock treatment 151320.0 -343.0 -0.01 146760.0 6730.0 0.18 0.1223 0.6706 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 E24 mock treatment 134600.0 -17100.0 -0.46 127640.0 -12400.0 -0.34 -0.56 -0.9885 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F01 compound treatment 177960.0 26300.0 0.7 135920.0 -4110.0 -0.11 0.4186 0.5878 3553427 CHDI2_000456 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F02 compound treatment 150480.0 -1180.0 -0.03 164440.0 24400.0 0.66 0.4448 0.6725 3553487 CHDI2_000457 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F03 compound treatment 53720.0 -97900.0 -2.62 39800.0 -100000.0 -2.71 -3.7713 -0.9998 3214416 CHDI2_000458 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F04 compound treatment 36160.0 -116000.0 -3.09 37760.0 -102000.0 -2.77 -4.1425 -0.9985 3214990 CHDI2_000459 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Br)s1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F05 compound treatment 139920.0 -11700.0 -0.31 141360.0 1330.0 0.04 -0.1967 -0.6222 3214420 CHDI2_000460 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F06 compound treatment 102920.0 -48700.0 -1.3 88560.0 -51500.0 -1.39 -1.9073 -0.9994 3214994 CHDI2_000461 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F07 compound treatment 118000.0 -33700.0 -0.9 120840.0 -19200.0 -0.52 -1.0041 -0.9659 3214424 CHDI2_000462 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F08 compound treatment 12720.0 -139000.0 -3.72 10080.0 -130000.0 -3.52 -5.1157 -0.9996 3214998 CHDI2_000463 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccccc2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F09 compound treatment 103200.0 -48500.0 -1.3 97200.0 -42800.0 -1.16 -1.7366 -0.9985 3553430 CHDI2_000464 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F10 compound treatment 137160.0 -14500.0 -0.39 134720.0 -5310.0 -0.14 -0.376 -0.9088 3553491 CHDI2_000465 CC(C)(C)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F11 compound treatment 159400.0 7740.0 0.21 127080.0 -13000.0 -0.35 -0.1016 -0.2496 3214428 CHDI2_000466 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F12 compound treatment 142840.0 -8820.0 -0.24 125960.0 -14100.0 -0.38 -0.4363 -0.9735 3215002 CHDI2_000467 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F13 compound treatment 103240.0 -48400.0 -1.3 103880.0 -36200.0 -0.98 -1.608 -0.9905 3214432 CHDI2_000468 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F14 compound treatment 139520.0 -12100.0 -0.32 141320.0 1290.0 0.03 -0.205 -0.6277 3215006 CHDI2_000469 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F15 compound treatment 136640.0 -15000.0 -0.4 123040.0 -17000.0 -0.46 -0.6095 -0.9977 3214436 CHDI2_000470 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F16 compound treatment 118960.0 -32700.0 -0.87 109160.0 -30900.0 -0.84 -1.2096 -0.9997 3215010 CHDI2_000471 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F17 compound treatment 11400.0 -140000.0 -3.75 11840.0 -128000.0 -3.47 -5.107 -0.9992 3553434 CHDI2_000472 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F18 compound treatment 142960.0 -8700.0 -0.23 128880.0 -11200.0 -0.3 -0.3781 -0.9917 3553494 CHDI2_000473 CC1=C(C/C=N/NC(=O)c2cccc(c2)C(=O)NO)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F19 compound treatment 95560.0 -56100.0 -1.5 90120.0 -49900.0 -1.35 -2.0166 -0.9986 3214440 CHDI2_000474 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F20 compound treatment 135480.0 -16200.0 -0.43 120760.0 -19300.0 -0.52 -0.675 -0.9957 3215014 CHDI2_000475 ONC(=O)CCCCC(=O)N/N=C/c1cccc(c1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F21 compound treatment 157440.0 5780.0 0.15 183920.0 43900.0 1.19 0.9494 0.7924 3214444 CHDI2_000476 CCCCCCC/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F22 compound treatment 159200.0 7540.0 0.2 123440.0 -16600.0 -0.45 -0.1751 -0.3556 3215018 CHDI2_000477 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F23 mock treatment 130520.0 -21100.0 -0.57 143080.0 3050.0 0.08 -0.3416 -0.5977 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 F24 mock treatment 147280.0 -4380.0 -0.12 134320.0 -5710.0 -0.15 -0.1923 -0.9907 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G01 compound treatment 15880.0 -136000.0 -3.63 17560.0 -122000.0 -3.32 -4.9128 -0.999 3214452 CHDI2_000478 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G02 compound treatment 106120.0 -45500.0 -1.22 87680.0 -52400.0 -1.42 -1.8636 -0.9972 3214454 CHDI2_000479 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G03 compound treatment 25280.0 -126000.0 -3.38 24000.0 -116000.0 -3.14 -4.6117 -0.9993 3214788 CHDI2_000480 Cn1cc(/C=N/NC(=O)CCCCCC(=O)NO)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G04 compound treatment 136120.0 -15500.0 -0.42 147480.0 7450.0 0.2 -0.1514 -0.3277 3553376 CHDI2_000481 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(I)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G05 compound treatment 40040.0 -112000.0 -2.99 39040.0 -101000.0 -2.73 -4.0446 -0.999 3214456 CHDI2_000482 ONC(=O)CCCCCC(=O)N/N=C/c1cccnc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G06 compound treatment 106040.0 -45600.0 -1.22 110360.0 -29700.0 -0.8 -1.431 -0.9794 3214458 CHDI2_000483 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccnc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G07 compound treatment 17680.0 -134000.0 -3.58 17040.0 -123000.0 -3.33 -4.8887 -0.9993 3214460 CHDI2_000484 ONC(=O)CCCCCC(=O)N/N=C/C=C/c1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G08 compound treatment 117600.0 -34100.0 -0.91 104160.0 -35900.0 -0.97 -1.331 -0.9995 3214462 CHDI2_000485 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G09 compound treatment 127440.0 -24200.0 -0.65 124560.0 -15500.0 -0.42 -0.7544 -0.9777 3214464 CHDI2_000486 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G10 compound treatment 142640.0 -9020.0 -0.24 148000.0 7970.0 0.22 -0.0182 -0.0561 3214466 CHDI2_000487 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G11 compound treatment 129160.0 -22500.0 -0.6 141400.0 1370.0 0.04 -0.3995 -0.6624 3214468 CHDI2_000488 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G12 compound treatment 142560.0 -9100.0 -0.24 139040.0 -994.0 -0.03 -0.1912 -0.7805 3214469 CHDI2_000489 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G13 compound treatment 36120.0 -116000.0 -3.09 33320.0 -107000.0 -2.89 -4.2282 -0.9994 3214470 CHDI2_000490 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(C#N)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G14 compound treatment 109240.0 -42400.0 -1.13 119320.0 -20700.0 -0.56 -1.1989 -0.9472 3214472 CHDI2_000491 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(C#N)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G15 compound treatment 132440.0 -19200.0 -0.51 138240.0 -1790.0 -0.05 -0.3979 -0.7705 3214474 CHDI2_000492 ONC(=O)CCCCCC(=O)N/N=C/C1CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G16 compound treatment 143720.0 -7940.0 -0.21 129920.0 -10100.0 -0.27 -0.3438 -0.9921 3214476 CHDI2_000493 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G17 compound treatment 18480.0 -133000.0 -3.56 15240.0 -125000.0 -3.38 -4.908 -0.9996 3214478 CHDI2_000494 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G18 compound treatment 99120.0 -52500.0 -1.41 103560.0 -36500.0 -0.99 -1.692 -0.9851 3214480 CHDI2_000495 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G19 compound treatment 11240.0 -140000.0 -3.76 10560.0 -129000.0 -3.51 -5.1345 -0.9994 3214792 CHDI2_000496 ONC(=O)CCCCCC(=O)N/N=C/c1cn(Cc2ccccc2)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G20 compound treatment 155360.0 3700.0 0.1 123680.0 -16400.0 -0.44 -0.2431 -0.536 3553380 CHDI2_000497 C/C=C(/C)\C=N\NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G21 compound treatment 10120.0 -142000.0 -3.79 9880.0 -130000.0 -3.52 -5.1687 -0.9994 3214482 CHDI2_000498 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)cc(Br)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G22 compound treatment 9000.0 -143000.0 -3.82 9080.0 -131000.0 -3.55 -5.2052 -0.9993 3214484 CHDI2_000499 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G23 mock treatment 138640.0 -13000.0 -0.35 135120.0 -4910.0 -0.13 -0.3404 -0.9128 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 G24 mock treatment 149560.0 -2100.0 -0.06 132640.0 -7390.0 -0.2 -0.1813 -0.872 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H01 compound treatment 148040.0 -3620.0 -0.1 122160.0 -17900.0 -0.48 -0.4107 -0.8322 3214490 CHDI2_000500 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H02 compound treatment 41600.0 -110000.0 -2.94 37920.0 -102000.0 -2.76 -4.0365 -0.9995 3215062 CHDI2_000501 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H03 compound treatment 169880.0 18200.0 0.49 168080.0 28000.0 0.76 0.8815 0.977 3553438 CHDI2_000502 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H04 compound treatment 170520.0 18900.0 0.5 160480.0 20400.0 0.55 0.7481 0.9989 3553498 CHDI2_000503 NC(=O)COc1ccccc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H05 compound treatment 102920.0 -48700.0 -1.3 110240.0 -29800.0 -0.81 -1.4923 -0.9733 3214494 CHDI2_000504 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H06 compound treatment 133480.0 -18200.0 -0.49 119880.0 -20200.0 -0.55 -0.7297 -0.9984 3215066 CHDI2_000505 ONC(=O)CCCCC(=O)N/N=C/c1cccnc1Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H07 compound treatment 158200.0 6540.0 0.17 167080.0 27000.0 0.73 0.6414 0.852 3214498 CHDI2_000506 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H08 compound treatment 112680.0 -39000.0 -1.04 111800.0 -28200.0 -0.76 -1.2778 -0.9883 3215070 CHDI2_000507 ONC(=O)CCCCC(=O)N/N=C/C=C/c1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H09 compound treatment 144600.0 -7060.0 -0.19 132080.0 -7950.0 -0.22 -0.2858 -0.9979 3214502 CHDI2_000508 Oc1cc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H10 compound treatment 171040.0 19400.0 0.52 153560.0 13500.0 0.37 0.6254 0.9855 3215074 CHDI2_000509 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H11 compound treatment 180640.0 29000.0 0.78 168160.0 28100.0 0.76 1.0865 1.0 3214506 CHDI2_000510 COc1cc(OC)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H12 compound treatment 165360.0 13700.0 0.37 147680.0 7650.0 0.21 0.4054 0.9635 3215078 CHDI2_000511 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H13 compound treatment 153680.0 2020.0 0.05 149560.0 9530.0 0.26 0.2205 0.8369 3214510 CHDI2_000512 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H14 compound treatment 138760.0 -12900.0 -0.35 144160.0 4130.0 0.11 -0.1651 -0.455 3215080 CHDI2_000513 ONC(=O)CCCCC(=O)N/N=C/c1ccc(C#N)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H15 compound treatment 163840.0 12200.0 0.33 162120.0 22100.0 0.6 0.6531 0.9592 3214514 CHDI2_000514 CC(C)(C)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H16 compound treatment 168760.0 17100.0 0.46 156320.0 16300.0 0.44 0.6352 0.9998 3215084 CHDI2_000515 ONC(=O)CCCCC(=O)N/N=C/C1CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H17 compound treatment 162400.0 10700.0 0.29 146040.0 6010.0 0.16 0.3181 0.9637 3214518 CHDI2_000516 CC1=C(C/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H18 compound treatment 35680.0 -116000.0 -3.1 63800.0 -76200.0 -2.06 -3.6531 -0.9804 3215088 CHDI2_000517 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H19 compound treatment 166880.0 15200.0 0.41 156280.0 16200.0 0.44 0.5988 0.9993 3553442 CHDI2_000518 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H20 compound treatment 173080.0 21400.0 0.57 160800.0 20800.0 0.56 0.8026 1.0 3553502 CHDI2_000519 NC(=O)COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H21 compound treatment 144680.0 -6980.0 -0.19 133400.0 -6630.0 -0.18 -0.2591 -0.9998 3214522 CHDI2_000520 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H22 compound treatment 10480.0 -141000.0 -3.78 10040.0 -130000.0 -3.52 -5.1589 -0.9994 3215092 CHDI2_000521 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)cc(Br)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H23 mock treatment 174000.0 22300.0 0.6 140800.0 766.0 0.02 0.4372 0.7312 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 H24 mock treatment 156720.0 5060.0 0.14 152840.0 12800.0 0.35 0.3408 0.9158 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I01 compound treatment 10560.0 -141000.0 -3.77 10960.0 -129000.0 -3.49 -5.1397 -0.9993 3214530 CHDI2_000522 COc1cc(Cl)c(/C=N/NC(=O)CCCCCC(=O)NO)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I02 compound treatment 144360.0 -7300.0 -0.2 134760.0 -5270.0 -0.14 -0.2391 -0.9881 3214532 CHDI2_000523 COc1cc(Cl)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I03 compound treatment 51560.0 -100000.0 -2.68 25520.0 -115000.0 -3.1 -4.0855 -0.9973 3214534 CHDI2_000524 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Cl)cc(Cl)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I04 compound treatment 12000.0 -140000.0 -3.74 12240.0 -128000.0 -3.46 -5.088 -0.9993 3214536 CHDI2_000525 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I05 compound treatment 41400.0 -110000.0 -2.95 43760.0 -96300.0 -2.61 -3.9285 -0.9981 3214796 CHDI2_000526 ONC(=O)CCCCCC(=O)N/N=C/C1=CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I06 compound treatment 147480.0 -4180.0 -0.11 155360.0 15300.0 0.41 0.2143 0.4986 3553384 CHDI2_000527 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I07 compound treatment 92640.0 -59000.0 -1.58 96040.0 -44000.0 -1.19 -1.9585 -0.9903 3214538 CHDI2_000528 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)cc([N+](=O)[O-])c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I08 compound treatment 69800.0 -81900.0 -2.19 65800.0 -74200.0 -2.01 -2.9694 -0.9991 3214540 CHDI2_000529 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I09 compound treatment 9800.0 -142000.0 -3.79 9800.0 -130000.0 -3.53 -5.1763 -0.9993 3214542 CHDI2_000530 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I10 compound treatment 11320.0 -140000.0 -3.75 12960.0 -127000.0 -3.44 -5.0871 -0.9991 3214544 CHDI2_000531 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I11 compound treatment 37880.0 -114000.0 -3.04 27920.0 -112000.0 -3.04 -4.2983 -1.0 3214546 CHDI2_000532 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2OCCc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I12 compound treatment 121160.0 -30500.0 -0.82 117480.0 -22600.0 -0.61 -1.0087 -0.9898 3214548 CHDI2_000533 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3OCCc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I13 compound treatment 101240.0 -50400.0 -1.35 90840.0 -49200.0 -1.33 -1.8954 -1.0 3214550 CHDI2_000534 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I14 compound treatment 58320.0 -93300.0 -2.5 54680.0 -85400.0 -2.31 -3.3994 -0.9993 3214552 CHDI2_000535 Oc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I15 compound treatment 100240.0 -51400.0 -1.38 97960.0 -42100.0 -1.14 -1.778 -0.9956 3214554 CHDI2_000536 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I16 compound treatment 63560.0 -88100.0 -2.36 59960.0 -80100.0 -2.17 -3.1993 -0.9991 3214556 CHDI2_000537 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I17 compound treatment 157080.0 5420.0 0.14 150480.0 10400.0 0.28 0.3024 0.9517 3214558 CHDI2_000538 ONC(=O)CCCCCC(=O)N/N=C/c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I18 compound treatment 159280.0 7620.0 0.2 163200.0 23200.0 0.63 0.5876 0.891 3214560 CHDI2_000539 Oc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I19 compound treatment 149240.0 -2420.0 -0.06 137440.0 -2590.0 -0.07 -0.0955 -0.9992 3214562 CHDI2_000540 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I20 compound treatment 158160.0 6500.0 0.17 154360.0 14300.0 0.39 0.3971 0.9344 3214564 CHDI2_000541 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I21 compound treatment 148760.0 -2900.0 -0.08 140120.0 86.5 0.0 -0.0533 -0.6855 3214799 CHDI2_000542 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I22 compound treatment 188320.0 36700.0 0.98 127480.0 -12600.0 -0.34 0.453 0.4365 3553388 CHDI2_000543 Cc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I23 mock treatment 153240.0 1580.0 0.04 164880.0 24800.0 0.67 0.5055 0.75 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 I24 mock treatment 165320.0 13700.0 0.37 146160.0 6130.0 0.17 0.3756 0.9362 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J01 compound treatment 212400.0 60700.0 1.62 154240.0 14200.0 0.38 1.4208 0.851 3214570 CHDI2_000544 Oc1ccccc1NC(=O)CCCCCC(=O)NN=C2CCCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J02 compound treatment 51640.0 -100000.0 -2.68 60320.0 -79700.0 -2.16 -3.4178 -0.9943 3215140 CHDI2_000545 COc1cc(Cl)c(/C=N/NC(=O)CCCCC(=O)NO)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J03 compound treatment 148760.0 -2900.0 -0.08 137040.0 -2990.0 -0.08 -0.1122 -0.9998 3214572 CHDI2_000546 Oc1ccccc1NC(=O)CCCCCC(=O)NN=C2CCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J04 compound treatment 23640.0 -128000.0 -3.42 35800.0 -104000.0 -2.82 -4.4168 -0.9954 3215144 CHDI2_000547 ONC(=O)CCCCC(=O)N/N=C/c1cc(Cl)cc(Cl)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J05 compound treatment 159560.0 7900.0 0.21 146200.0 6170.0 0.17 0.2674 0.9932 3553446 CHDI2_000548 Cc1ncc(CO)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J06 compound treatment 128880.0 -22800.0 -0.61 132520.0 -7510.0 -0.2 -0.5748 -0.8946 3554234 CHDI2_000549 ONC(=O)c1cccc(c1)C(=O)NN=C2CCCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J07 compound treatment 134520.0 -17100.0 -0.46 138880.0 -1150.0 -0.03 -0.3463 -0.7535 3214574 CHDI2_000550 Oc1ccccc1NC(=O)CCCCCC(=O)NN=C2CCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J08 compound treatment 104160.0 -47500.0 -1.27 107200.0 -32800.0 -0.89 -1.527 -0.9847 3215148 CHDI2_000551 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)cc([N+](=O)[O-])c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J09 compound treatment 127920.0 -23700.0 -0.64 141440.0 1410.0 0.04 -0.4222 -0.6635 3214215 CHDI2_000552 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J10 compound treatment 12600.0 -139000.0 -3.72 17080.0 -123000.0 -3.33 -4.984 -0.9985 3215152 CHDI2_000553 CCN(CC)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J11 compound treatment 33960.0 -118000.0 -3.15 28560.0 -111000.0 -3.02 -4.3602 -0.9998 3214576 CHDI2_000554 COc1cc(Br)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J12 compound treatment 105440.0 -46200.0 -1.24 109200.0 -30800.0 -0.83 -1.4645 -0.9817 3215156 CHDI2_000555 ONC(=O)CCCCC(=O)N/N=C/c1ccc2OCCc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J13 compound treatment 97520.0 -54100.0 -1.45 93880.0 -46200.0 -1.25 -1.9076 -0.9973 3214580 CHDI2_000556 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/CCC2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J14 compound treatment 84320.0 -67300.0 -1.8 83920.0 -56100.0 -1.52 -2.3479 -0.9964 3215160 CHDI2_000557 ONC(=O)CCCCC(=O)N/N=C/c1cccc(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J15 compound treatment 82280.0 -69400.0 -1.86 88880.0 -51200.0 -1.38 -2.2916 -0.9896 3214584 CHDI2_000558 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J16 compound treatment 113000.0 -38700.0 -1.03 134520.0 -5510.0 -0.15 -0.8368 -0.8009 3215164 CHDI2_000559 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J17 compound treatment 140040.0 -11600.0 -0.31 138760.0 -1270.0 -0.03 -0.2442 -0.7807 3214588 CHDI2_000560 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J18 compound treatment 139880.0 -11800.0 -0.32 141360.0 1330.0 0.04 -0.1975 -0.6225 3215168 CHDI2_000561 ONC(=O)CCCCC(=O)N/N=C/c1cc(O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J19 compound treatment 136040.0 -15600.0 -0.42 136320.0 -3710.0 -0.1 -0.3666 -0.8529 3214215 CHDI2_000562 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J20 compound treatment 138400.0 -13300.0 -0.35 149040.0 9010.0 0.24 -0.0784 -0.1822 3215172 CHDI2_000563 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J21 compound treatment 129400.0 -22300.0 -0.6 148560.0 8530.0 0.23 -0.2579 -0.4037 3553450 CHDI2_000564 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J22 compound treatment 134920.0 -16700.0 -0.45 125560.0 -14500.0 -0.39 -0.5937 -0.9978 3554232 CHDI2_000565 ONC(=O)c1cccc(c1)C(=O)NN=C2CCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J23 mock treatment 134080.0 -17600.0 -0.47 121680.0 -18400.0 -0.5 -0.6839 -0.9996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 J24 mock treatment 172080.0 20400.0 0.55 123480.0 -16600.0 -0.45 0.0693 0.0981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K01 compound treatment 205520.0 53900.0 1.44 147160.0 7130.0 0.19 1.1551 0.7947 3214592 CHDI2_000566 COc1cccc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K02 compound treatment 145640.0 -6020.0 -0.16 136400.0 -3630.0 -0.1 -0.1835 -0.972 3214594 CHDI2_000567 COc1cccc(OC)c1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K03 compound treatment 61600.0 -90100.0 -2.41 85320.0 -54700.0 -1.48 -2.7509 -0.9727 3214596 CHDI2_000568 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K04 compound treatment 114920.0 -36700.0 -0.98 122200.0 -17800.0 -0.48 -1.0364 -0.9464 3214598 CHDI2_000569 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K05 compound treatment 124480.0 -27200.0 -0.73 120680.0 -19400.0 -0.52 -0.8846 -0.9871 3214600 CHDI2_000570 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K06 compound treatment 135560.0 -16100.0 -0.43 125560.0 -14500.0 -0.39 -0.5816 -0.9989 3214602 CHDI2_000571 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K07 compound treatment 140760.0 -10900.0 -0.29 131160.0 -8870.0 -0.24 -0.3761 -0.9954 3214802 CHDI2_000572 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K08 compound treatment 126720.0 -24900.0 -0.67 138000.0 -2030.0 -0.06 -0.5107 -0.7629 3553391 CHDI2_000573 Cc1[nH]cnc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K09 compound treatment 136280.0 -15400.0 -0.41 149200.0 9170.0 0.25 -0.1155 -0.2403 3214604 CHDI2_000574 CC1(C)COC(CCC/C=N/NC(=O)CCCCCC(=O)NO)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K10 compound treatment 134840.0 -16800.0 -0.45 143280.0 3250.0 0.09 -0.256 -0.5584 3214606 CHDI2_000575 CC1(C)COC(CCC/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K11 compound treatment 136480.0 -15200.0 -0.41 147960.0 7930.0 0.21 -0.1354 -0.2949 3214608 CHDI2_000576 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K12 compound treatment 120440.0 -31200.0 -0.84 138560.0 -1470.0 -0.04 -0.6188 -0.74 3214610 CHDI2_000577 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCC(=O)Nc3ccccc3O)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K13 compound treatment 15040.0 -137000.0 -3.65 14320.0 -126000.0 -3.4 -4.9907 -0.9994 3214612 CHDI2_000578 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)cs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K14 compound treatment 59680.0 -92000.0 -2.46 65760.0 -74300.0 -2.01 -3.1616 -0.995 3214614 CHDI2_000579 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)cs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K15 compound treatment 133520.0 -18100.0 -0.49 132080.0 -7950.0 -0.22 -0.4954 -0.9331 3214806 CHDI2_000580 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K16 compound treatment 124600.0 -27100.0 -0.72 139240.0 -794.0 -0.02 -0.5271 -0.7278 3553395 CHDI2_000581 Cc1ccsc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K17 compound treatment 114920.0 -36700.0 -0.98 129720.0 -10300.0 -0.28 -0.8924 -0.8734 3214616 CHDI2_000582 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K18 compound treatment 132560.0 -19100.0 -0.51 136800.0 -3230.0 -0.09 -0.4232 -0.8164 3214618 CHDI2_000583 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K19 compound treatment 9600.0 -142000.0 -3.8 10040.0 -130000.0 -3.52 -5.1755 -0.9993 3214620 CHDI2_000584 ONC(=O)CCCCCC(=O)N/N=C/c1ccc-2c(Cc3ccccc32)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K20 compound treatment 24360.0 -127000.0 -3.41 53600.0 -86400.0 -2.34 -4.0624 -0.9832 3214622 CHDI2_000585 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K21 compound treatment 32800.0 -119000.0 -3.18 30000.0 -110000.0 -2.98 -4.3546 -0.9995 3214624 CHDI2_000586 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(F)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K22 compound treatment 132640.0 -19000.0 -0.51 111400.0 -28600.0 -0.78 -0.9079 -0.9792 3214626 CHDI2_000587 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(F)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K23 mock treatment 139040.0 -12600.0 -0.34 126560.0 -13500.0 -0.36 -0.4967 -0.9993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 K24 mock treatment 148600.0 -3060.0 -0.08 139200.0 -834.0 -0.02 -0.0739 -0.8695 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L01 compound treatment 195240.0 43600.0 1.17 137200.0 -2830.0 -0.08 0.77 0.6591 3214628 CHDI2_000588 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L02 compound treatment 152240.0 577.0 0.02 132640.0 -7390.0 -0.2 -0.1306 -0.6506 3215202 CHDI2_000589 COc1cccc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L03 compound treatment 156000.0 4340.0 0.12 146760.0 6730.0 0.18 0.2108 0.9763 3214632 CHDI2_000590 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L04 compound treatment 149440.0 -2220.0 -0.06 124320.0 -15700.0 -0.43 -0.3429 -0.7982 3215206 CHDI2_000591 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L05 compound treatment 143680.0 -7980.0 -0.21 141320.0 1290.0 0.03 -0.1264 -0.5841 3214636 CHDI2_000592 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L06 compound treatment 156160.0 4500.0 0.12 175640.0 35600.0 0.96 0.7667 0.7892 3215210 CHDI2_000593 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L07 compound treatment 137480.0 -14200.0 -0.38 143360.0 3330.0 0.09 -0.2046 -0.5247 3553454 CHDI2_000594 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L08 compound treatment 129600.0 -22100.0 -0.59 150880.0 10800.0 0.29 -0.2097 -0.3181 3553643 CHDI2_000595 ONC(=O)c1cccc(c1)C(=O)N/N=C/Cc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L09 compound treatment 120240.0 -31400.0 -0.84 134880.0 -5150.0 -0.14 -0.693 -0.8134 3214640 CHDI2_000596 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L10 compound treatment 129880.0 -21800.0 -0.58 136240.0 -3790.0 -0.1 -0.4846 -0.8191 3215214 CHDI2_000597 CC1(C)COC(CCC/C=N/NC(=O)CCCCC(=O)NO)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L11 compound treatment 128280.0 -23400.0 -0.63 127360.0 -12700.0 -0.34 -0.6849 -0.96 3214642 CHDI2_000598 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L12 compound treatment 132320.0 -19300.0 -0.52 127240.0 -12800.0 -0.35 -0.6108 -0.981 3215218 CHDI2_000599 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCC(=O)NO)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L13 compound treatment 127160.0 -24500.0 -0.66 127000.0 -13000.0 -0.35 -0.713 -0.9578 3214644 CHDI2_000600 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L14 compound treatment 87760.0 -63900.0 -1.71 85800.0 -54200.0 -1.47 -2.2469 -0.9971 3215222 CHDI2_000601 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)cs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L15 compound treatment 76280.0 -75400.0 -2.02 63840.0 -76200.0 -2.06 -2.8844 -0.9999 3553458 CHDI2_000602 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L16 compound treatment 134280.0 -17400.0 -0.46 158680.0 18600.0 0.5 0.0282 0.041 3553647 CHDI2_000603 COC(=O)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L17 compound treatment 27240.0 -124000.0 -3.33 44520.0 -95500.0 -2.59 -4.1818 -0.9922 3214648 CHDI2_000604 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L18 compound treatment 125000.0 -26700.0 -0.71 133080.0 -6950.0 -0.19 -0.6374 -0.8642 3215226 CHDI2_000605 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L19 compound treatment 138120.0 -13500.0 -0.36 140680.0 646.0 0.02 -0.2438 -0.6722 3214652 CHDI2_000606 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L20 compound treatment 8680.0 -143000.0 -3.82 9760.0 -130000.0 -3.53 -5.1983 -0.9992 3215230 CHDI2_000607 ONC(=O)CCCCC(=O)N/N=C/c1ccc-2c(Cc3ccccc32)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L21 compound treatment 88200.0 -63500.0 -1.7 88960.0 -51100.0 -1.38 -2.1781 -0.9948 3214656 CHDI2_000608 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3ccccc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L22 compound treatment 123800.0 -27900.0 -0.75 121600.0 -18400.0 -0.5 -0.8799 -0.981 3215234 CHDI2_000609 ONC(=O)CCCCC(=O)N/N=C/c1ccc(F)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L23 mock treatment 145560.0 -6100.0 -0.16 123040.0 -17000.0 -0.46 -0.4407 -0.9029 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 L24 mock treatment 140680.0 -11000.0 -0.29 126560.0 -13500.0 -0.36 -0.4657 -0.9942 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M01 compound treatment 148320.0 -3340.0 -0.09 133920.0 -6110.0 -0.17 -0.1803 -0.9582 3214660 CHDI2_000610 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M02 compound treatment 175680.0 24000.0 0.64 123880.0 -16200.0 -0.44 0.145 0.1866 3214662 CHDI2_000611 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M03 compound treatment 7800.0 -144000.0 -3.85 10640.0 -129000.0 -3.5 -5.1981 -0.9989 3214664 CHDI2_000612 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(F)c(Oc2ccccc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M04 compound treatment 7040.0 -145000.0 -3.87 8960.0 -131000.0 -3.55 -5.2446 -0.9991 3214666 CHDI2_000613 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M05 compound treatment 20640.0 -131000.0 -3.5 24760.0 -115000.0 -3.12 -4.6849 -0.9983 3214668 CHDI2_000614 ONC(=O)CCCCCC(=O)N/N=C/c1cc(F)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M06 compound treatment 55360.0 -96300.0 -2.58 67120.0 -72900.0 -1.97 -3.2173 -0.9914 3214670 CHDI2_000615 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(F)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M07 compound treatment 121760.0 -29900.0 -0.8 124080.0 -16000.0 -0.43 -0.871 -0.9582 3214672 CHDI2_000616 ONC(=O)CCCCCC(=O)N/N=C/c1coc2ccccc2c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M08 compound treatment 148640.0 -3020.0 -0.08 136160.0 -3870.0 -0.1 -0.1313 -0.9917 3214674 CHDI2_000617 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M09 compound treatment 39480.0 -112000.0 -3.0 56480.0 -83600.0 -2.26 -3.7213 -0.9903 3214814 CHDI2_000618 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M10 compound treatment 143320.0 -8340.0 -0.22 167480.0 27400.0 0.74 0.3676 0.4738 3553403 CHDI2_000619 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M11 compound treatment 21120.0 -131000.0 -3.49 24680.0 -115000.0 -3.12 -4.6774 -0.9984 3214676 CHDI2_000620 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M12 compound treatment 53280.0 -98400.0 -2.63 56400.0 -83600.0 -2.26 -3.4618 -0.9972 3214678 CHDI2_000621 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M13 compound treatment 125440.0 -26200.0 -0.7 125400.0 -14600.0 -0.4 -0.7761 -0.9634 3214818 CHDI2_000622 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M14 compound treatment 156120.0 4460.0 0.12 156680.0 16600.0 0.45 0.403 0.8644 3553407 CHDI2_000623 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3ccccc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M15 compound treatment 117000.0 -34700.0 -0.93 117040.0 -23000.0 -0.62 -1.0958 -0.9812 3214680 CHDI2_000624 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(c1)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M16 compound treatment 119240.0 -32400.0 -0.87 119040.0 -21000.0 -0.57 -1.0151 -0.979 3214682 CHDI2_000625 OB(O)c1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M17 compound treatment 51440.0 -100000.0 -2.68 73280.0 -66800.0 -1.81 -3.1735 -0.9816 3214684 CHDI2_000626 ONC(=O)CCCCCC(=O)N/N=C/c1ccco1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M18 compound treatment 120240.0 -31400.0 -0.84 124080.0 -16000.0 -0.43 -0.8997 -0.9521 3214686 CHDI2_000627 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccco2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M19 compound treatment 79680.0 -72000.0 -1.93 92480.0 -47600.0 -1.29 -2.2718 -0.9808 3214688 CHDI2_000628 ONC(=O)CCCCCC(=O)N/N=C/c1ccoc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M20 compound treatment 130600.0 -21100.0 -0.56 118040.0 -22000.0 -0.6 -0.8194 -0.9996 3214690 CHDI2_000629 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccoc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M21 compound treatment 103840.0 -47800.0 -1.28 101640.0 -38400.0 -1.04 -1.6395 -0.9947 3214692 CHDI2_000630 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M22 compound treatment 103520.0 -48100.0 -1.29 113320.0 -26700.0 -0.72 -1.422 -0.9628 3214694 CHDI2_000631 Oc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M23 mock treatment 170280.0 18600.0 0.5 149280.0 9250.0 0.25 0.5291 0.9494 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 M24 mock treatment 140640.0 -11000.0 -0.29 124880.0 -15200.0 -0.41 -0.4986 -0.9869 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N01 compound treatment 86640.0 -65000.0 -1.74 101840.0 -38200.0 -1.03 -1.961 -0.9692 3214700 CHDI2_000632 Cc1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N02 compound treatment 159200.0 7540.0 0.2 149440.0 9410.0 0.25 0.3226 0.9933 3215270 CHDI2_000633 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c(F)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N03 compound treatment 124400.0 -27300.0 -0.73 134720.0 -5310.0 -0.14 -0.6174 -0.8306 3214704 CHDI2_000634 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N04 compound treatment 22600.0 -129000.0 -3.45 54240.0 -85800.0 -2.32 -4.0835 -0.9814 3215274 CHDI2_000635 ONC(=O)CCCCC(=O)N/N=C/c1ccc(F)c(Oc2ccccc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N05 compound treatment 142640.0 -9020.0 -0.24 134280.0 -5750.0 -0.16 -0.2808 -0.9776 3214708 CHDI2_000636 O[C@@H](/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N06 compound treatment 69600.0 -82100.0 -2.2 88400.0 -51600.0 -1.4 -2.5406 -0.9763 3215278 CHDI2_000637 ONC(=O)CCCCC(=O)N/N=C/c1cc(F)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N07 compound treatment 129800.0 -21900.0 -0.58 135960.0 -4070.0 -0.11 -0.4915 -0.8259 3214712 CHDI2_000638 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N08 compound treatment 138840.0 -12800.0 -0.34 133280.0 -6750.0 -0.18 -0.3718 -0.9566 3215282 CHDI2_000639 ONC(=O)CCCCC(=O)N/N=C/c1coc2ccccc2c1=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N09 compound treatment 117560.0 -34100.0 -0.91 150400.0 10400.0 0.28 -0.4466 -0.4679 3553466 CHDI2_000640 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2nccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N10 compound treatment 152440.0 777.0 0.02 154720.0 14700.0 0.4 0.2958 0.7431 3553651 CHDI2_000641 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc3ccccc3n2S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N11 compound treatment 114200.0 -37500.0 -1.0 107080.0 -33000.0 -0.89 -1.3394 -0.9983 3214714 CHDI2_000642 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N12 compound treatment 40600.0 -111000.0 -2.97 43560.0 -96500.0 -2.61 -3.9475 -0.9979 3215286 CHDI2_000643 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N13 compound treatment 132560.0 -19100.0 -0.51 132320.0 -7710.0 -0.21 -0.509 -0.9221 3553471 CHDI2_000644 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N14 compound treatment 8920.0 -143000.0 -3.82 10480.0 -130000.0 -3.51 -5.1799 -0.9991 3553510 CHDI2_000645 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N15 compound treatment 93000.0 -58700.0 -1.57 98440.0 -41600.0 -1.13 -1.9058 -0.9868 3214718 CHDI2_000646 CCOc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N16 compound treatment 130640.0 -21000.0 -0.56 150200.0 10200.0 0.28 -0.203 -0.3243 3215290 CHDI2_000647 ONC(=O)CCCCC(=O)N/N=C/c1cccc(c1)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N17 compound treatment 8200.0 -143000.0 -3.84 10600.0 -129000.0 -3.5 -5.1913 -0.999 3214722 CHDI2_000648 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N18 compound treatment 121840.0 -29800.0 -0.8 133520.0 -6510.0 -0.18 -0.6888 -0.8431 3215294 CHDI2_000649 ONC(=O)CCCCC(=O)N/N=C/c1ccco1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N19 compound treatment 146120.0 -5540.0 -0.15 132560.0 -7470.0 -0.2 -0.2479 -0.9883 3214726 CHDI2_000650 CN(C)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N20 compound treatment 128640.0 -23000.0 -0.62 116480.0 -23600.0 -0.64 -0.8863 -0.9998 3215298 CHDI2_000651 ONC(=O)CCCCC(=O)N/N=C/c1ccoc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N21 compound treatment 97880.0 -53800.0 -1.44 102040.0 -38000.0 -1.03 -1.7446 -0.9865 3214730 CHDI2_000652 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCC(=O)Nc4ccccc4O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N22 compound treatment 125360.0 -26300.0 -0.7 127360.0 -12700.0 -0.34 -0.7401 -0.9455 3215302 CHDI2_000653 ONC(=O)CCCCC(=O)N/N=C/c1cccc(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N23 mock treatment 135720.0 -15900.0 -0.43 115800.0 -24200.0 -0.66 -0.7655 -0.9782 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 N24 mock treatment 158240.0 6580.0 0.18 136080.0 -3950.0 -0.11 0.0487 0.2366 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O01 compound treatment 98880.0 -52800.0 -1.41 98640.0 -41400.0 -1.12 -1.7908 -0.9935 3214738 CHDI2_000654 OCCOc1ccccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O02 compound treatment 188640.0 37000.0 0.99 125800.0 -14200.0 -0.39 0.4269 0.4022 3214740 CHDI2_000655 OCCOc1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O03 compound treatment 121600.0 -30100.0 -0.8 115560.0 -24500.0 -0.66 -1.0371 -0.9954 3214742 CHDI2_000656 OCCOc1cccc(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O04 compound treatment 120440.0 -31200.0 -0.84 124320.0 -15700.0 -0.43 -0.8914 -0.951 3214744 CHDI2_000657 OCCOc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O05 compound treatment 52080.0 -99600.0 -2.66 102240.0 -37800.0 -1.02 -2.607 -0.9136 3214746 CHDI2_000658 OCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O06 compound treatment 119920.0 -31700.0 -0.85 121120.0 -18900.0 -0.51 -0.9625 -0.9707 3214748 CHDI2_000659 OCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O07 compound treatment 13800.0 -138000.0 -3.69 29760.0 -110000.0 -2.99 -4.7186 -0.9945 3214750 CHDI2_000660 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O08 compound treatment 43440.0 -108000.0 -2.89 54360.0 -85700.0 -2.32 -3.687 -0.994 3214752 CHDI2_000661 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O09 compound treatment 13800.0 -138000.0 -3.69 37840.0 -102000.0 -2.77 -4.5639 -0.99 3214754 CHDI2_000662 COc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O10 compound treatment 33000.0 -119000.0 -3.17 49720.0 -90300.0 -2.45 -3.9733 -0.9917 3214756 CHDI2_000663 COc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O11 compound treatment 53120.0 -98500.0 -2.64 81680.0 -58400.0 -1.58 -2.9809 -0.97 3214822 CHDI2_000664 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O12 compound treatment 130520.0 -21100.0 -0.57 135840.0 -4190.0 -0.11 -0.4802 -0.8324 3553411 CHDI2_000665 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O13 compound treatment 73720.0 -77900.0 -2.08 92960.0 -47100.0 -1.27 -2.3754 -0.9721 3214758 CHDI2_000666 COc1cc(/C=C/C=N/NC(=O)CCCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O14 compound treatment 99840.0 -51800.0 -1.39 104160.0 -35900.0 -0.97 -1.6669 -0.9849 3214760 CHDI2_000667 COc1cc(/C=C/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O15 compound treatment 8000.0 -144000.0 -3.84 15360.0 -125000.0 -3.38 -5.1039 -0.9979 3214762 CHDI2_000668 Cc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O16 compound treatment 25200.0 -126000.0 -3.38 50640.0 -89400.0 -2.42 -4.1032 -0.9865 3214764 CHDI2_000669 Cc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O17 compound treatment 110120.0 -41500.0 -1.11 121160.0 -18900.0 -0.51 -1.1471 -0.9379 3214766 CHDI2_000670 OCc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O18 compound treatment 110920.0 -40700.0 -1.09 126720.0 -13300.0 -0.36 -1.0255 -0.8934 3214768 CHDI2_000671 OCc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O19 compound treatment 6000.0 -146000.0 -3.9 10280.0 -130000.0 -3.51 -5.239 -0.9987 3214770 CHDI2_000672 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2ccccc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O20 compound treatment 14800.0 -137000.0 -3.66 11480.0 -129000.0 -3.48 -5.0496 -0.9997 3214772 CHDI2_000673 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3ccccc3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O21 compound treatment 5200.0 -146000.0 -3.92 6360.0 -134000.0 -3.62 -5.3292 -0.9992 3214774 CHDI2_000674 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(o1)c2cccc(Cl)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O22 compound treatment 7800.0 -144000.0 -3.85 9240.0 -131000.0 -3.54 -5.2249 -0.9991 3214776 CHDI2_000675 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O23 mock treatment 140000.0 -11700.0 -0.31 134480.0 -5550.0 -0.15 -0.3269 -0.944 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 O24 mock treatment 167920.0 16300.0 0.43 133320.0 -6710.0 -0.18 0.179 0.3797 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P01 compound treatment 192960.0 41300.0 1.1 147480.0 7450.0 0.2 0.9237 0.8226 3214782 CHDI2_000676 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P02 compound treatment 150320.0 -1340.0 -0.04 138520.0 -1510.0 -0.04 -0.0544 -0.9978 3215348 CHDI2_000677 OCCOc1ccccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P03 compound treatment 122200.0 -29500.0 -0.79 115960.0 -24100.0 -0.65 -1.0181 -0.9955 3214786 CHDI2_000678 Cn1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P04 compound treatment 108080.0 -43600.0 -1.17 121600.0 -18400.0 -0.5 -1.1772 -0.9283 3215352 CHDI2_000679 OCCOc1cccc(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P05 compound treatment 24120.0 -128000.0 -3.41 30280.0 -110000.0 -2.97 -4.5134 -0.9976 3214790 CHDI2_000680 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P06 compound treatment 116520.0 -35100.0 -0.94 142000.0 1970.0 0.05 -0.6271 -0.666 3215356 CHDI2_000681 OCCOc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P07 compound treatment 116240.0 -35400.0 -0.95 125360.0 -14700.0 -0.4 -0.9509 -0.9255 3214794 CHDI2_000682 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C2=CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P08 compound treatment 81360.0 -70300.0 -1.88 93320.0 -46700.0 -1.26 -2.224 -0.9814 3215360 CHDI2_000683 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P09 compound treatment 108600.0 -43100.0 -1.15 135560.0 -4470.0 -0.12 -0.9001 -0.7772 3214798 CHDI2_000684 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P10 compound treatment 81800.0 -69900.0 -1.87 108200.0 -31800.0 -0.86 -1.9308 -0.9382 3215364 CHDI2_000685 COc1ccc(O)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P11 compound treatment 115400.0 -36300.0 -0.97 118560.0 -21500.0 -0.58 -1.097 -0.97 3553474 CHDI2_000686 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P12 compound treatment 125440.0 -26200.0 -0.7 145160.0 5130.0 0.14 -0.3978 -0.5564 3553514 CHDI2_000687 ONC(=O)c1cccc(c1)C(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P13 compound treatment 116800.0 -34900.0 -0.93 131720.0 -8310.0 -0.23 -0.8186 -0.8533 3214800 CHDI2_000688 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P14 compound treatment 125720.0 -25900.0 -0.69 128840.0 -11200.0 -0.3 -0.705 -0.931 3215368 CHDI2_000689 COc1cc(/C=C/C=N/NC(=O)CCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P15 compound treatment 116920.0 -34700.0 -0.93 121080.0 -19000.0 -0.51 -1.02 -0.9608 3214804 CHDI2_000690 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P16 compound treatment 13280.0 -138000.0 -3.7 48720.0 -91300.0 -2.47 -4.3654 -0.9807 3215372 CHDI2_000691 Cc1ccc(O)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P17 compound treatment 114560.0 -37100.0 -0.99 141680.0 1650.0 0.04 -0.6703 -0.6747 3214808 CHDI2_000692 C/C(=N\NC(=O)CCCCCC(=O)Nc1ccccc1O)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P18 compound treatment 106120.0 -45500.0 -1.22 117760.0 -22300.0 -0.6 -1.2878 -0.9474 3215376 CHDI2_000693 OCc1ccc(/C=N/NC(=O)CCCCC(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P19 compound treatment 77880.0 -73800.0 -1.97 97360.0 -42700.0 -1.16 -2.2125 -0.9675 3214812 CHDI2_000694 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P20 compound treatment 7080.0 -145000.0 -3.87 22000.0 -118000.0 -3.2 -4.9942 -0.9955 3215380 CHDI2_000695 ONC(=O)CCCCC(=O)N/N=C/c1ccc2ccccc2c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P21 compound treatment 114040.0 -37600.0 -1.01 103080.0 -37000.0 -1.0 -1.419 -1.0 3214816 CHDI2_000696 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P22 compound treatment 4760.0 -147000.0 -3.93 5280.0 -135000.0 -3.65 -5.3582 -0.9993 3215384 CHDI2_000697 ONC(=O)CCCCC(=O)N/N=C/c1ccc(o1)c2cccc(Cl)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P23 mock treatment 139360.0 -12300.0 -0.33 128680.0 -11400.0 -0.31 -0.45 -0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2404 P24 mock treatment 153320.0 1660.0 0.04 131760.0 -8270.0 -0.22 -0.127 -0.5564 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A01 compound treatment 6520.0 -133000.0 -3.55 6840.0 -143000.0 -3.86 -5.24 -0.9991 3214868 CHDI2_000698 ONC(=O)CCCCC(=O)N/N=C/c1c(O)ccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A02 compound treatment 196600.0 57400.0 1.54 204720.0 55300.0 1.5 2.1433 0.9999 3551921 CHDI2_000699 NNC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A03 compound treatment 150760.0 11600.0 0.31 196600.0 47100.0 1.28 1.1208 0.8537 3214872 CHDI2_000700 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A04 compound treatment 196480.0 57300.0 1.53 193880.0 44400.0 1.2 1.9335 0.9928 3552997 CHDI2_000701 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A05 compound treatment 166240.0 27000.0 0.72 201600.0 52100.0 1.41 1.5093 0.9517 3214876 CHDI2_000702 ONC(=O)CCCCC(=O)N/N=C/c1ccc([N+](=O)[O-])c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A06 compound treatment 193400.0 54200.0 1.45 191800.0 42300.0 1.15 1.8354 0.9932 3553001 CHDI2_000703 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A07 compound treatment 172680.0 33500.0 0.9 180960.0 31500.0 0.85 1.236 0.9997 3214880 CHDI2_000704 ONC(=O)CCCCC(=O)N/N=C/c1cc(O)ccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A08 compound treatment 178000.0 38800.0 1.04 186760.0 37300.0 1.01 1.4476 0.9999 3553005 CHDI2_000705 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A09 compound treatment 168160.0 29000.0 0.77 182360.0 32900.0 0.89 1.1773 0.9976 3214884 CHDI2_000706 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)n2ccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A10 compound treatment 174200.0 35000.0 0.94 175960.0 26500.0 0.72 1.169 0.9914 3553009 CHDI2_000707 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3OCCOc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A11 compound treatment 116120.0 -23100.0 -0.62 173640.0 24200.0 0.65 0.0261 0.029 3214888 CHDI2_000708 ONC(=O)CCCCC(=O)N/N=C/c1c[nH]c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A12 compound treatment 172360.0 33200.0 0.89 175760.0 26300.0 0.71 1.1304 0.9941 3553013 CHDI2_000709 ONC(=O)c1cccc(c1)C(=O)N/N=C/COCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A13 compound treatment 183320.0 44100.0 1.18 193600.0 44100.0 1.19 1.6792 1.0 3553655 CHDI2_000710 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A14 compound treatment 193240.0 54000.0 1.45 207920.0 58500.0 1.58 2.141 0.999 3553589 CHDI2_000711 CCOc1cccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A15 compound treatment 51960.0 -87200.0 -2.33 81720.0 -67700.0 -1.83 -2.9471 -0.9929 3214892 CHDI2_000712 ONC(=O)CCCCC(=O)N/N=C/c1ccc(I)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A16 compound treatment 160160.0 21000.0 0.56 183400.0 33900.0 0.92 1.0459 0.9719 3553017 CHDI2_000713 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A17 compound treatment 171000.0 31800.0 0.85 183040.0 33600.0 0.91 1.244 0.9994 3214896 CHDI2_000714 C/C=C(/C)\C=N\NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A18 compound treatment 214040.0 74800.0 2.0 207640.0 58200.0 1.57 2.529 0.993 3553021 CHDI2_000715 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A19 compound treatment 112680.0 -26500.0 -0.71 182960.0 33500.0 0.91 0.1394 0.1211 3214972 CHDI2_000716 ONC(=O)CCCCC(=O)N/N=C/c1ccc(s1)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A20 compound treatment 191200.0 52000.0 1.39 192920.0 43500.0 1.18 1.8152 0.9965 3553025 CHDI2_000717 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A21 compound treatment 174760.0 35600.0 0.95 191320.0 41900.0 1.13 1.4737 0.9962 3214904 CHDI2_000718 Cc1ccc(/C=N/NC(=O)CCCCC(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A22 compound treatment 214920.0 75700.0 2.03 219480.0 70000.0 1.9 2.7723 0.9995 3553029 CHDI2_000719 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Br)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A23 mock treatment 203960.0 64800.0 1.73 207920.0 58500.0 1.58 2.3437 0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 A24 mock treatment 185800.0 46600.0 1.25 191720.0 42300.0 1.14 1.6901 0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B01 compound treatment 198720.0 59500.0 1.59 216640.0 67200.0 1.82 2.4115 0.9978 3551923 CHDI2_000720 NNC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B02 compound treatment 10160.0 -129000.0 -3.45 11120.0 -138000.0 -3.75 -5.0892 -0.9992 3553956 CHDI2_000721 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B03 compound treatment 183560.0 44400.0 1.19 182320.0 32900.0 0.89 1.4678 0.9899 3553662 CHDI2_000722 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B04 compound treatment 152360.0 13200.0 0.35 160840.0 11400.0 0.31 0.4665 0.9978 3553960 CHDI2_000723 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B05 compound treatment 130520.0 -8690.0 -0.23 178560.0 29100.0 0.79 0.3926 0.4781 3553666 CHDI2_000724 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B06 compound treatment 125200.0 -14000.0 -0.37 199320.0 49900.0 1.35 0.6894 0.4922 3553964 CHDI2_000725 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B07 compound treatment 112440.0 -26800.0 -0.72 169280.0 19800.0 0.54 -0.127 -0.1419 3553670 CHDI2_000726 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B08 compound treatment 118000.0 -21200.0 -0.57 153240.0 3770.0 0.1 -0.3289 -0.5706 3553968 CHDI2_000727 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(O)ccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B09 compound treatment 132880.0 -6330.0 -0.17 162880.0 13400.0 0.36 0.1371 0.3422 3553675 CHDI2_000728 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3OCCOc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B10 compound treatment 124960.0 -14200.0 -0.38 148440.0 -1030.0 -0.03 -0.2891 -0.7566 3553971 CHDI2_000729 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B11 compound treatment 131760.0 -7450.0 -0.2 154640.0 5170.0 0.14 -0.0418 -0.1717 3553679 CHDI2_000730 ONC(=O)c1ccc(cc1)C(=O)N/N=C/COCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B12 compound treatment 142320.0 3110.0 0.08 157080.0 7610.0 0.21 0.2046 0.9204 3553975 CHDI2_000731 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c[nH]c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B13 compound treatment 13080.0 -126000.0 -3.37 13560.0 -136000.0 -3.68 -4.9873 -0.9991 3552713 CHDI2_000732 Oc1ccc2ccccc2c1/C=N/NC(=O)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B14 compound treatment 141880.0 2670.0 0.07 156360.0 6890.0 0.19 0.1825 0.9132 3552763 CHDI2_000733 COc1cc(/C=N/NC(=O)c2ccccn2)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B15 compound treatment 137640.0 -1570.0 -0.04 163720.0 14300.0 0.39 0.2432 0.6265 3553682 CHDI2_000734 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B16 compound treatment 129280.0 -9930.0 -0.27 153440.0 3970.0 0.11 -0.1117 -0.3899 3553978 CHDI2_000735 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(I)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B17 compound treatment 148200.0 8990.0 0.24 184480.0 35000.0 0.95 0.8404 0.8593 3553686 CHDI2_000736 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B18 compound treatment 159120.0 19900.0 0.53 185320.0 35900.0 0.97 1.063 0.9601 3553981 CHDI2_000737 C/C=C(/C)\C=N\NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B19 compound treatment 177040.0 37800.0 1.01 146480.0 -2990.0 -0.08 0.6584 0.6486 3553690 CHDI2_000738 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B20 compound treatment 130240.0 -8970.0 -0.24 181160.0 31700.0 0.86 0.4371 0.4906 3553985 CHDI2_000739 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B21 compound treatment 149040.0 9830.0 0.26 164360.0 14900.0 0.4 0.4711 0.9786 3553695 CHDI2_000740 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Br)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B22 compound treatment 212440.0 73200.0 1.96 197840.0 48400.0 1.31 2.3112 0.9808 3553989 CHDI2_000741 Cc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B23 mock treatment 197280.0 58100.0 1.55 187640.0 38200.0 1.03 1.8292 0.9804 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 B24 mock treatment 194840.0 55600.0 1.49 202080.0 52600.0 1.42 2.0594 0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C01 compound treatment 34160.0 -105000.0 -2.81 48080.0 -101000.0 -2.74 -3.9278 -0.9999 3214952 CHDI2_000742 Cc1ccsc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C02 compound treatment 182120.0 42900.0 1.15 189920.0 40500.0 1.1 1.5861 0.9997 3553037 CHDI2_000743 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Br)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C03 compound treatment 130600.0 -8610.0 -0.23 138280.0 -11200.0 -0.3 -0.377 -0.9909 3214956 CHDI2_000744 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C04 compound treatment 127480.0 -11700.0 -0.31 166400.0 16900.0 0.46 0.1023 0.1842 3553041 CHDI2_000745 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C05 compound treatment 10080.0 -129000.0 -3.45 12920.0 -137000.0 -3.7 -5.0563 -0.9994 3214960 CHDI2_000746 ONC(=O)CCCCC(=O)N/N=C/c1cccc2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C06 compound treatment 127720.0 -11500.0 -0.31 157760.0 8290.0 0.22 -0.0585 -0.1537 3553045 CHDI2_000747 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(O)ccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C07 compound treatment 7880.0 -131000.0 -3.51 11560.0 -138000.0 -3.73 -5.1239 -0.9995 3214968 CHDI2_000748 ONC(=O)CCCCC(=O)N/N=C/c1ccc2ccccc2c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C08 compound treatment 40960.0 -98200.0 -2.63 34760.0 -115000.0 -3.11 -4.0541 -0.9966 3553049 CHDI2_000749 COc1cc(Br)cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C09 compound treatment 46800.0 -92400.0 -2.47 97120.0 -52300.0 -1.42 -2.7499 -0.9651 3214900 CHDI2_000750 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C10 compound treatment 136240.0 -2970.0 -0.08 150560.0 1090.0 0.03 -0.0352 -0.4153 3553053 CHDI2_000751 COc1ccc(Br)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C11 compound treatment 135520.0 -3690.0 -0.1 155200.0 5730.0 0.16 0.04 0.2175 3553658 CHDI2_000752 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCC#C)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C12 compound treatment 11120.0 -128000.0 -3.43 14200.0 -135000.0 -3.66 -5.0121 -0.9994 3553593 CHDI2_000753 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C13 compound treatment 109520.0 -29700.0 -0.79 110200.0 -39300.0 -1.06 -1.3132 -0.9897 3214964 CHDI2_000754 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C14 compound treatment 134720.0 -4490.0 -0.12 187080.0 37600.0 1.02 0.6352 0.6195 3553057 CHDI2_000755 COc1ccc(Br)cc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C15 compound treatment 135040.0 -4170.0 -0.11 144160.0 -5310.0 -0.14 -0.1804 -0.9922 3553517 CHDI2_000756 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C16 compound treatment 124920.0 -14300.0 -0.38 172960.0 23500.0 0.64 0.1795 0.2419 3553597 CHDI2_000757 CN(C)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C17 compound treatment 134880.0 -4330.0 -0.12 156320.0 6850.0 0.19 0.0493 0.2256 3214976 CHDI2_000758 ONC(=O)CCCCC(=O)N/N=C/c1c(F)c(F)c(F)c(F)c1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C18 compound treatment 133920.0 -5290.0 -0.14 158080.0 8610.0 0.23 0.0649 0.2379 3553061 CHDI2_000759 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C19 compound treatment 120880.0 -18300.0 -0.49 142680.0 -6790.0 -0.18 -0.4766 -0.9103 3214980 CHDI2_000760 ONC(=O)CCCCC(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C20 compound treatment 133480.0 -5730.0 -0.15 175680.0 26200.0 0.71 0.3935 0.542 3553065 CHDI2_000761 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccnc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C21 compound treatment 120640.0 -18600.0 -0.5 154920.0 5450.0 0.15 -0.2468 -0.4763 3214984 CHDI2_000762 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C22 compound treatment 149920.0 10700.0 0.29 182480.0 33000.0 0.89 0.8346 0.8892 3553069 CHDI2_000763 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccncc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C23 mock treatment 159960.0 20800.0 0.56 191080.0 41600.0 1.13 1.1891 0.9468 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 C24 mock treatment 176320.0 37100.0 0.99 189400.0 39900.0 1.08 1.4664 0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D01 compound treatment 170120.0 30900.0 0.83 166920.0 17500.0 0.47 0.9188 0.9648 3553703 CHDI2_000764 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Br)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D02 compound treatment 136600.0 -2610.0 -0.07 147480.0 -1990.0 -0.05 -0.0873 -0.9917 3553995 CHDI2_000765 Cc1ccsc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D03 compound treatment 144560.0 5350.0 0.14 149680.0 214.0 0.01 0.1053 0.7351 3553706 CHDI2_000766 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D04 compound treatment 179560.0 40400.0 1.08 217120.0 67700.0 1.83 2.0583 0.9682 3553998 CHDI2_000767 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3ccc(cc3)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D05 compound treatment 137680.0 -1530.0 -0.04 166000.0 16500.0 0.45 0.2876 0.6399 3553710 CHDI2_000768 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(O)ccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D06 compound treatment 86400.0 -52800.0 -1.41 103760.0 -45700.0 -1.24 -1.8738 -0.9978 3554002 CHDI2_000769 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D07 compound treatment 23320.0 -116000.0 -3.1 19560.0 -130000.0 -3.52 -4.6787 -0.998 3553714 CHDI2_000770 COc1cc(Br)cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D08 compound treatment 124080.0 -15100.0 -0.4 142480.0 -6990.0 -0.19 -0.4199 -0.94 3554006 CHDI2_000771 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3ccccc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D09 compound treatment 112600.0 -26600.0 -0.71 128120.0 -21300.0 -0.58 -0.9119 -0.9947 3553718 CHDI2_000772 COc1ccc(Br)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D10 compound treatment 133000.0 -6210.0 -0.17 140200.0 -9270.0 -0.25 -0.2948 -0.9799 3554009 CHDI2_000773 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D11 compound treatment 131880.0 -7330.0 -0.2 124360.0 -25100.0 -0.68 -0.6192 -0.8754 3552716 CHDI2_000774 Oc1ccc(/C=N/NC(=O)c2ccccn2)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D12 compound treatment 147280.0 8070.0 0.22 163520.0 14100.0 0.38 0.4217 0.964 3552765 CHDI2_000775 Fc1c(F)c(F)c(/C=N/NC(=O)c2ccccn2)c(F)c1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D13 compound treatment 163720.0 24500.0 0.66 154160.0 4690.0 0.13 0.5535 0.8287 3553722 CHDI2_000776 COc1ccc(Br)cc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D14 compound treatment 142400.0 3190.0 0.09 173560.0 24100.0 0.65 0.5216 0.7929 3554013 CHDI2_000777 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D15 compound treatment 117840.0 -21400.0 -0.57 157000.0 7530.0 0.2 -0.2599 -0.4283 3552720 CHDI2_000778 Oc1cc(/C=N/NC(=O)c2ccccn2)ccc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D16 compound treatment 133440.0 -5770.0 -0.15 169080.0 19600.0 0.53 0.2664 0.4817 3552767 CHDI2_000779 C=CCC/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D17 compound treatment 102400.0 -36800.0 -0.98 140800.0 -8670.0 -0.23 -0.8621 -0.8518 3553726 CHDI2_000780 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D18 compound treatment 133480.0 -5730.0 -0.15 174560.0 25100.0 0.68 0.372 0.5342 3554017 CHDI2_000781 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D19 compound treatment 128920.0 -10300.0 -0.28 178040.0 28600.0 0.77 0.3524 0.4292 3553730 CHDI2_000782 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccnc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D20 compound treatment 132360.0 -6850.0 -0.18 144240.0 -5230.0 -0.14 -0.2296 -0.9918 3554021 CHDI2_000783 ONC(=O)c1ccc(cc1)C(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D21 compound treatment 128120.0 -11100.0 -0.3 153880.0 4410.0 0.12 -0.1252 -0.3916 3553734 CHDI2_000784 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccncc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D22 compound treatment 105080.0 -34100.0 -0.91 111440.0 -38000.0 -1.03 -1.3734 -0.9982 3554025 CHDI2_000785 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D23 mock treatment 154320.0 15100.0 0.4 159400.0 9930.0 0.27 0.476 0.9804 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 D24 mock treatment 158120.0 18900.0 0.51 159400.0 9930.0 0.27 0.5479 0.9563 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E01 compound treatment 179320.0 40100.0 1.07 171200.0 21700.0 0.59 1.1747 0.96 3553522 CHDI2_000786 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E02 compound treatment 8400.0 -131000.0 -3.5 9480.0 -140000.0 -3.79 -5.1539 -0.9992 3553601 CHDI2_000787 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4cccc(c4)C(=O)NO)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E03 compound treatment 8240.0 -131000.0 -3.5 9240.0 -140000.0 -3.8 -5.1615 -0.9992 3215028 CHDI2_000788 ONC(=O)CCCCC(=O)N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E04 compound treatment 125360.0 -13800.0 -0.37 141480.0 -7990.0 -0.22 -0.4148 -0.9671 3553077 CHDI2_000789 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Br)s2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E05 compound treatment 114600.0 -24600.0 -0.66 133160.0 -16300.0 -0.44 -0.7776 -0.9811 3215032 CHDI2_000790 ONC(=O)CCCCC(=O)N/N=C/c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E06 compound treatment 134600.0 -4610.0 -0.12 143800.0 -5670.0 -0.15 -0.1956 -0.9941 3553081 CHDI2_000791 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E07 compound treatment 102920.0 -36300.0 -0.97 121640.0 -27800.0 -0.75 -1.219 -0.9921 3215036 CHDI2_000792 ONC(=O)CCCCC(=O)N/N=C/c1cccnc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E08 compound treatment 10280.0 -129000.0 -3.45 11240.0 -138000.0 -3.74 -5.0847 -0.9992 3553084 CHDI2_000793 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E09 compound treatment 110840.0 -28400.0 -0.76 131080.0 -18400.0 -0.5 -0.8885 -0.9791 3553525 CHDI2_000794 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E10 compound treatment 31880.0 -107000.0 -2.87 42440.0 -107000.0 -2.9 -4.0788 -1.0 3553605 CHDI2_000795 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E11 compound treatment 113760.0 -25400.0 -0.68 119000.0 -30500.0 -0.82 -1.0645 -0.9955 3215040 CHDI2_000796 Cc1ncc(CO)c(/C=N/NC(=O)CCCCC(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E12 compound treatment 120440.0 -18800.0 -0.5 133880.0 -15600.0 -0.42 -0.6533 -0.9963 3553088 CHDI2_000797 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E13 compound treatment 122640.0 -16600.0 -0.44 130440.0 -19000.0 -0.52 -0.6776 -0.9972 3215044 CHDI2_000798 ONC(=O)CCCCC(=O)N/N=C/c1ccc[nH]1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E14 compound treatment 128360.0 -10800.0 -0.29 122320.0 -27100.0 -0.73 -0.7248 -0.9174 3553092 CHDI2_000799 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E15 compound treatment 89160.0 -50000.0 -1.34 93680.0 -55800.0 -1.51 -2.0145 -0.9982 3215048 CHDI2_000800 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)N2CCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E16 compound treatment 110640.0 -28600.0 -0.76 148400.0 -1070.0 -0.03 -0.5608 -0.7333 3553096 CHDI2_000801 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E17 compound treatment 124080.0 -15100.0 -0.4 141120.0 -8350.0 -0.23 -0.4459 -0.9621 3553530 CHDI2_000802 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E18 compound treatment 118560.0 -20600.0 -0.55 137120.0 -12300.0 -0.33 -0.6269 -0.9711 3553608 CHDI2_000803 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E19 compound treatment 86880.0 -52300.0 -1.4 114200.0 -35300.0 -0.95 -1.6648 -0.9826 3215052 CHDI2_000804 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E20 compound treatment 139720.0 512.0 0.01 136000.0 -13500.0 -0.36 -0.2481 -0.6801 3553100 CHDI2_000805 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(c2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E21 compound treatment 124440.0 -14800.0 -0.4 140920.0 -8550.0 -0.23 -0.4429 -0.9675 3215056 CHDI2_000806 CCCCCCC/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E22 compound treatment 123200.0 -16000.0 -0.43 150000.0 534.0 0.01 -0.2926 -0.6828 3553104 CHDI2_000807 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E23 mock treatment 125000.0 -14200.0 -0.38 133880.0 -15600.0 -0.42 -0.5671 -0.9986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 E24 mock treatment 135560.0 -3650.0 -0.1 133360.0 -16100.0 -0.44 -0.3773 -0.8445 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F01 compound treatment 185120.0 45900.0 1.23 179200.0 29700.0 0.8 1.4376 0.979 1936929 CHDI2_000808 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F02 compound treatment 73280.0 -65900.0 -1.76 77080.0 -72400.0 -1.96 -2.6327 -0.9986 3552769 CHDI2_000809 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F03 compound treatment 99400.0 -39800.0 -1.06 105000.0 -44500.0 -1.2 -1.6042 -0.9981 3553741 CHDI2_000810 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Br)s2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F04 compound treatment 9440.0 -130000.0 -3.47 10520.0 -139000.0 -3.76 -5.1143 -0.9992 3554032 CHDI2_000811 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F05 compound treatment 127200.0 -12000.0 -0.32 131680.0 -17800.0 -0.48 -0.5676 -0.9806 3553745 CHDI2_000812 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F06 compound treatment 131440.0 -7770.0 -0.21 140520.0 -8950.0 -0.24 -0.3182 -0.9971 3554034 CHDI2_000813 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F07 compound treatment 10920.0 -128000.0 -3.43 11240.0 -138000.0 -3.74 -5.0726 -0.9991 3553748 CHDI2_000814 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F08 compound treatment 127160.0 -12000.0 -0.32 115640.0 -33800.0 -0.92 -0.8754 -0.9017 3554036 CHDI2_000815 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F09 compound treatment 110160.0 -29000.0 -0.78 122880.0 -26600.0 -0.72 -1.0584 -0.9993 3552725 CHDI2_000816 O=C(N/N=C/c1ccc(cc1)n2ccnc2)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F10 compound treatment 109240.0 -30000.0 -0.8 109760.0 -39700.0 -1.07 -1.3269 -0.9896 3552771 CHDI2_000817 O=C(N/N=C/c1cccc(Oc2ccccc2)c1)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F11 compound treatment 117880.0 -21300.0 -0.57 128160.0 -21300.0 -0.58 -0.8113 -1.0 3553752 CHDI2_000818 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F12 compound treatment 110600.0 -28600.0 -0.77 118440.0 -31000.0 -0.84 -1.135 -0.9989 3554038 CHDI2_000819 Cc1ncc(CO)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F13 compound treatment 137240.0 -1970.0 -0.05 119960.0 -29500.0 -0.8 -0.6021 -0.7521 3553756 CHDI2_000820 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F14 compound treatment 124600.0 -14600.0 -0.39 129400.0 -20100.0 -0.54 -0.6604 -0.9869 3554040 CHDI2_000821 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F15 compound treatment 106480.0 -32700.0 -0.88 117560.0 -31900.0 -0.86 -1.2298 -1.0 3553759 CHDI2_000822 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F16 compound treatment 68160.0 -71000.0 -1.9 73160.0 -76300.0 -2.07 -2.8046 -0.9991 3554042 CHDI2_000823 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F17 compound treatment 131840.0 -7370.0 -0.2 130040.0 -19400.0 -0.53 -0.5112 -0.9103 3552730 CHDI2_000824 O=C(N/N=C/c1c[nH]c2ccccc12)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F18 compound treatment 116560.0 -22600.0 -0.61 112320.0 -37100.0 -1.01 -1.1395 -0.9706 3552773 CHDI2_000825 O=C(N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3)c4ccccn4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F19 compound treatment 121000.0 -18200.0 -0.49 144840.0 -4630.0 -0.13 -0.4329 -0.8609 3553763 CHDI2_000826 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(c2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F20 compound treatment 62960.0 -76200.0 -2.04 68600.0 -80900.0 -2.19 -2.9902 -0.9994 3554044 CHDI2_000827 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F21 compound treatment 138040.0 -1170.0 -0.03 150280.0 814.0 0.02 -0.0065 -0.1703 3553767 CHDI2_000828 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F22 compound treatment 122960.0 -16200.0 -0.43 121440.0 -28000.0 -0.76 -0.8438 -0.965 3554046 CHDI2_000829 CCCCCCC/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F23 mock treatment 150080.0 10900.0 0.29 143440.0 -6030.0 -0.16 0.0903 0.2707 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 F24 mock treatment 140720.0 1510.0 0.04 163600.0 14100.0 0.38 0.2992 0.7775 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G01 compound treatment 145400.0 6190.0 0.17 151520.0 2050.0 0.06 0.1564 0.8954 3215102 CHDI2_000830 ONC(=O)CCCCC(=O)N/N=C/c1cccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G02 compound treatment 142240.0 3030.0 0.08 181080.0 31600.0 0.86 0.6625 0.7707 3553111 CHDI2_000831 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G03 compound treatment 139960.0 752.0 0.02 129560.0 -19900.0 -0.54 -0.3668 -0.6802 3553531 CHDI2_000832 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G04 compound treatment 133160.0 -6050.0 -0.16 139400.0 -10100.0 -0.27 -0.3071 -0.969 3553612 CHDI2_000833 Cn1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G05 compound treatment 86080.0 -53100.0 -1.42 86800.0 -62700.0 -1.7 -2.2045 -0.9961 3215106 CHDI2_000834 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G06 compound treatment 106680.0 -32500.0 -0.87 126920.0 -22500.0 -0.61 -1.0468 -0.985 3553115 CHDI2_000835 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccnc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G07 compound treatment 117040.0 -22200.0 -0.59 113840.0 -35600.0 -0.96 -1.1013 -0.9727 3215110 CHDI2_000836 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G08 compound treatment 116200.0 -23000.0 -0.62 124000.0 -25500.0 -0.69 -0.9227 -0.9984 3553118 CHDI2_000837 ONC(=O)c1cccc(c1)C(=O)N/N=C/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G09 compound treatment 100120.0 -39100.0 -1.05 111520.0 -37900.0 -1.03 -1.4657 -1.0 3215114 CHDI2_000838 ONC(=O)CCCCC(=O)N/N=C/c1c(O)cc(O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G10 compound treatment 107920.0 -31300.0 -0.84 117480.0 -32000.0 -0.87 -1.2041 -0.9999 3553123 CHDI2_000839 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G11 compound treatment 113720.0 -25500.0 -0.68 129400.0 -20100.0 -0.54 -0.8662 -0.9937 3215118 CHDI2_000840 COc1cc(OC)c(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G12 compound treatment 118320.0 -20900.0 -0.56 121240.0 -28200.0 -0.76 -0.9354 -0.9882 3553127 CHDI2_000841 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G13 compound treatment 112520.0 -26700.0 -0.71 109120.0 -40300.0 -1.09 -1.2771 -0.9788 3215122 CHDI2_000842 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G14 compound treatment 112320.0 -26900.0 -0.72 112440.0 -37000.0 -1.0 -1.2174 -0.9867 3553128 CHDI2_000843 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(C#N)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G15 compound treatment 111080.0 -28100.0 -0.75 126040.0 -23400.0 -0.63 -0.9805 -0.9964 3215126 CHDI2_000844 CC(C)(C)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G16 compound treatment 101240.0 -38000.0 -1.02 114320.0 -35100.0 -0.95 -1.3909 -0.9995 3553133 CHDI2_000845 ONC(=O)c1cccc(c1)C(=O)N/N=C/C2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G17 compound treatment 117600.0 -21600.0 -0.58 127880.0 -21600.0 -0.58 -0.8219 -1.0 3215130 CHDI2_000846 CC1=C(C/C=N/NC(=O)CCCCC(=O)NO)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G18 compound treatment 122920.0 -16300.0 -0.44 124520.0 -24900.0 -0.68 -0.7856 -0.9775 3553137 CHDI2_000847 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G19 compound treatment 115000.0 -24200.0 -0.65 138640.0 -10800.0 -0.29 -0.6651 -0.9358 3553533 CHDI2_000848 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G20 compound treatment 125320.0 -13900.0 -0.37 139000.0 -10500.0 -0.28 -0.463 -0.9911 3553614 CHDI2_000849 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G21 compound treatment 146960.0 7750.0 0.21 144240.0 -5230.0 -0.14 0.0466 0.1856 3215134 CHDI2_000850 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G22 compound treatment 9440.0 -130000.0 -3.47 10600.0 -139000.0 -3.76 -5.1128 -0.9992 3553141 CHDI2_000851 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G23 mock treatment 121960.0 -17200.0 -0.46 123680.0 -25800.0 -0.7 -0.8199 -0.9798 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 G24 mock treatment 131520.0 -7690.0 -0.21 138040.0 -11400.0 -0.31 -0.3641 -0.9803 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H01 compound treatment 167360.0 28200.0 0.75 177760.0 28300.0 0.77 1.0741 1.0 3553774 CHDI2_000852 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H02 compound treatment 140240.0 1030.0 0.03 141600.0 -7870.0 -0.21 -0.1311 -0.6104 3554050 CHDI2_000853 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H03 compound treatment 106440.0 -32800.0 -0.88 119840.0 -29600.0 -0.8 -1.1869 -0.999 3552734 CHDI2_000854 Ic1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H04 compound treatment 125240.0 -14000.0 -0.37 156840.0 7370.0 0.2 -0.123 -0.2904 3552775 CHDI2_000855 O=C(N/N=C/c1ccccn1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H05 compound treatment 114480.0 -24700.0 -0.66 119080.0 -30400.0 -0.82 -1.0494 -0.9942 3553778 CHDI2_000856 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccnc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H06 compound treatment 101440.0 -37800.0 -1.01 115280.0 -34200.0 -0.93 -1.3688 -0.999 3554054 CHDI2_000857 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H07 compound treatment 110120.0 -29100.0 -0.78 105200.0 -44300.0 -1.2 -1.3976 -0.9781 3553782 CHDI2_000858 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H08 compound treatment 126360.0 -12800.0 -0.34 121320.0 -28100.0 -0.76 -0.7818 -0.9353 3554058 CHDI2_000859 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c(O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H09 compound treatment 120240.0 -19000.0 -0.51 114040.0 -35400.0 -0.96 -1.0369 -0.9557 3553785 CHDI2_000860 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H10 compound treatment 102200.0 -37000.0 -0.99 103400.0 -46100.0 -1.25 -1.5818 -0.9935 3554062 CHDI2_000861 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c(O)cc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H11 compound treatment 112840.0 -26400.0 -0.71 108440.0 -41000.0 -1.11 -1.2841 -0.976 3553788 CHDI2_000862 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H12 compound treatment 123400.0 -15800.0 -0.42 132080.0 -17400.0 -0.47 -0.6318 -0.9986 3554066 CHDI2_000863 COc1cc(OC)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H13 compound treatment 101880.0 -37300.0 -1.0 110440.0 -39000.0 -1.06 -1.4531 -0.9996 3553791 CHDI2_000864 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(C#N)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H14 compound treatment 122240.0 -17000.0 -0.45 129440.0 -20000.0 -0.54 -0.7043 -0.9961 3554070 CHDI2_000865 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H15 compound treatment 110200.0 -29000.0 -0.78 118040.0 -31400.0 -0.85 -1.1503 -0.9989 3553793 CHDI2_000866 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H16 compound treatment 110800.0 -28400.0 -0.76 120440.0 -29000.0 -0.79 -1.093 -0.9999 3554074 CHDI2_000867 CC(C)(C)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H17 compound treatment 97920.0 -41300.0 -1.1 100880.0 -48600.0 -1.32 -1.711 -0.9962 3553797 CHDI2_000868 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H18 compound treatment 153920.0 14700.0 0.39 128760.0 -20700.0 -0.56 -0.1181 -0.1725 3554078 CHDI2_000869 CC1=C(C/C=N/NC(=O)c2ccc(cc2)C(=O)NO)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H19 compound treatment 106360.0 -32800.0 -0.88 137040.0 -12400.0 -0.34 -0.8592 -0.9132 3552737 CHDI2_000870 C/C=C(/C)\C=N\NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H20 compound treatment 101800.0 -37400.0 -1.0 119120.0 -30300.0 -0.82 -1.2885 -0.9952 3552777 CHDI2_000871 O=C(N/N=C/c1cccnc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H21 compound treatment 10080.0 -129000.0 -3.45 11080.0 -138000.0 -3.75 -5.0915 -0.9992 3553801 CHDI2_000872 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H22 compound treatment 123320.0 -15900.0 -0.42 126800.0 -22700.0 -0.61 -0.7344 -0.9839 3554082 CHDI2_000873 NC(=O)COc1ccccc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H23 mock treatment 120640.0 -18600.0 -0.5 149120.0 -346.0 -0.01 -0.3578 -0.7203 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 H24 mock treatment 116600.0 -22600.0 -0.6 125240.0 -24200.0 -0.66 -0.8914 -0.9992 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I01 compound treatment 181760.0 42600.0 1.14 172320.0 22900.0 0.62 1.2423 0.959 3215181 CHDI2_000874 ONC(=O)CCCCC(=O)NN=C1CCCCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I02 compound treatment 177840.0 38600.0 1.03 195760.0 46300.0 1.25 1.6169 0.9954 3553148 CHDI2_000875 COc1cc(Cl)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I03 compound treatment 121560.0 -17600.0 -0.47 132640.0 -16800.0 -0.46 -0.6559 -0.9998 3215183 CHDI2_000876 ONC(=O)CCCCC(=O)NN=C1CCCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I04 compound treatment 17240.0 -122000.0 -3.26 14440.0 -135000.0 -3.66 -4.8918 -0.9984 3553152 CHDI2_000877 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I05 compound treatment 18320.0 -121000.0 -3.23 19760.0 -130000.0 -3.51 -4.7695 -0.9992 3553537 CHDI2_000878 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I06 compound treatment 114320.0 -24900.0 -0.67 116720.0 -32700.0 -0.89 -1.0976 -0.99 3553618 CHDI2_000879 ONC(=O)c1cccc(c1)C(=O)N/N=C/C2=CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I07 compound treatment 119160.0 -20000.0 -0.54 128000.0 -21500.0 -0.58 -0.7901 -0.9992 3215185 CHDI2_000880 ONC(=O)CCCCC(=O)NN=C1CCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I08 compound treatment 116520.0 -22700.0 -0.61 108800.0 -40700.0 -1.1 -1.2076 -0.9606 3553156 CHDI2_000881 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I09 compound treatment 113200.0 -26000.0 -0.7 119760.0 -29700.0 -0.8 -1.0606 -0.9974 3214824 CHDI2_000882 NNC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I10 compound treatment 12600.0 -127000.0 -3.39 11680.0 -138000.0 -3.73 -5.0324 -0.9988 3553212 CHDI2_000883 CCN(CC)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I11 compound treatment 16520.0 -123000.0 -3.28 23240.0 -126000.0 -3.42 -4.7369 -0.9998 3215188 CHDI2_000884 COc1cc(Br)c(/C=N/NC(=O)CCCCC(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I12 compound treatment 121040.0 -18200.0 -0.49 138200.0 -11300.0 -0.3 -0.5593 -0.9748 3553216 CHDI2_000885 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3OCCc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I13 compound treatment 114560.0 -24600.0 -0.66 120400.0 -29100.0 -0.79 -1.0226 -0.9961 3215192 CHDI2_000886 ONC(=O)CCCCC(=O)N/N=C/CCC1CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I14 compound treatment 89720.0 -49500.0 -1.32 86040.0 -63400.0 -1.72 -2.1502 -0.9917 3553220 CHDI2_000887 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I15 compound treatment 10960.0 -128000.0 -3.43 10400.0 -139000.0 -3.76 -5.0879 -0.9989 3215196 CHDI2_000888 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I16 compound treatment 113360.0 -25800.0 -0.69 112680.0 -36800.0 -1.0 -1.1931 -0.9841 3553224 CHDI2_000889 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I17 compound treatment 131600.0 -7610.0 -0.2 129120.0 -20300.0 -0.55 -0.5334 -0.9083 3215200 CHDI2_000890 ONC(=O)CCCCC(=O)N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I18 compound treatment 124160.0 -15000.0 -0.4 146800.0 -2670.0 -0.07 -0.3357 -0.8208 3553228 CHDI2_000891 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(O)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I19 compound treatment 146120.0 6910.0 0.18 129680.0 -19800.0 -0.54 -0.248 -0.4377 3214824 CHDI2_000892 NNC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I20 compound treatment 144000.0 4790.0 0.13 172200.0 22700.0 0.62 0.5258 0.8364 3553231 CHDI2_000893 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I21 compound treatment 122040.0 -17200.0 -0.46 141080.0 -8390.0 -0.23 -0.4853 -0.9472 3553541 CHDI2_000894 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I22 compound treatment 126320.0 -12900.0 -0.34 135000.0 -14500.0 -0.39 -0.5207 -0.998 3553622 CHDI2_000895 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I23 mock treatment 150960.0 11800.0 0.31 132120.0 -17300.0 -0.47 -0.1098 -0.1943 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 I24 mock treatment 129200.0 -10000.0 -0.27 152720.0 3250.0 0.09 -0.127 -0.4506 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J01 compound treatment 179680.0 40500.0 1.08 169000.0 19500.0 0.53 1.1394 0.9457 3553809 CHDI2_000896 COc1cc(Cl)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J02 compound treatment 151960.0 12800.0 0.34 167080.0 17600.0 0.48 0.5784 0.9865 3554238 CHDI2_000897 ONC(=O)c1ccc(cc1)C(=O)NN=C2CCCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J03 compound treatment 42960.0 -96200.0 -2.57 39440.0 -110000.0 -2.98 -3.9267 -0.9974 3553812 CHDI2_000898 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J04 compound treatment 124160.0 -15000.0 -0.4 151440.0 1970.0 0.05 -0.2468 -0.6079 3554236 CHDI2_000899 ONC(=O)c1ccc(cc1)C(=O)NN=C2CCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J05 compound treatment 136000.0 -3210.0 -0.09 125520.0 -23900.0 -0.65 -0.5191 -0.7938 3552741 CHDI2_000900 [O-][N+](=O)c1ccc(/C=N/NC(=O)c2ccccn2)s1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J06 compound treatment 114480.0 -24700.0 -0.66 117480.0 -32000.0 -0.87 -1.08 -0.9912 3552779 CHDI2_000901 Cc1ncc(CO)c(/C=N/NC(=O)c2ccccn2)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J07 compound treatment 130160.0 -9050.0 -0.24 111800.0 -37700.0 -1.02 -0.8922 -0.8513 3553816 CHDI2_000902 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J08 compound treatment 126800.0 -12400.0 -0.33 116920.0 -32500.0 -0.88 -0.8577 -0.911 3554206 CHDI2_000903 ONC(=O)c1ccc(cc1)C(=O)N/N=C/Cc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J09 compound treatment 11880.0 -127000.0 -3.41 10640.0 -139000.0 -3.76 -5.0659 -0.9988 3553820 CHDI2_000904 CCN(CC)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J10 compound treatment 125280.0 -13900.0 -0.37 122840.0 -26600.0 -0.72 -0.7731 -0.9528 3554209 CHDI2_000905 COC(=O)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J11 compound treatment 99640.0 -39600.0 -1.06 100160.0 -49300.0 -1.33 -1.6923 -0.9934 3553823 CHDI2_000906 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3OCCc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J12 compound treatment 117680.0 -21500.0 -0.58 125440.0 -24000.0 -0.65 -0.8671 -0.9982 3554090 CHDI2_000907 COc1cc(Br)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J13 compound treatment 46280.0 -92900.0 -2.49 59480.0 -90000.0 -2.44 -3.4803 -0.9999 3553827 CHDI2_000908 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(O)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J14 compound treatment 146200.0 6990.0 0.19 138760.0 -10700.0 -0.29 -0.0727 -0.2108 3554213 CHDI2_000909 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc3ccccc3n2S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J15 compound treatment 96440.0 -42800.0 -1.14 93200.0 -56300.0 -1.52 -1.886 -0.99 3553831 CHDI2_000910 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J16 compound treatment 12080.0 -127000.0 -3.4 10600.0 -139000.0 -3.76 -5.0629 -0.9987 3554094 CHDI2_000911 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J17 compound treatment 152400.0 13200.0 0.35 152880.0 3410.0 0.09 0.3149 0.8632 3553835 CHDI2_000912 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(O)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J18 compound treatment 120280.0 -18900.0 -0.51 117920.0 -31500.0 -0.85 -0.9619 -0.9688 3554098 CHDI2_000913 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J19 compound treatment 158720.0 19500.0 0.52 157040.0 7570.0 0.21 0.514 0.9167 3553839 CHDI2_000914 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J20 compound treatment 125800.0 -13400.0 -0.36 108360.0 -41100.0 -1.11 -1.0405 -0.8899 3554217 CHDI2_000915 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J21 compound treatment 146040.0 6830.0 0.18 128320.0 -21100.0 -0.57 -0.2756 -0.4586 3552745 CHDI2_000916 Cc1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J22 compound treatment 160080.0 20900.0 0.56 173000.0 23500.0 0.64 0.8453 0.9978 1936582 CHDI2_000917 O=C(N/N=C/c1ccc[nH]1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J23 mock treatment 127400.0 -11800.0 -0.32 130200.0 -19300.0 -0.52 -0.5922 -0.9711 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 J24 mock treatment 124800.0 -14400.0 -0.39 157720.0 8250.0 0.22 -0.1145 -0.257 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K01 compound treatment 163720.0 24500.0 0.66 163160.0 13700.0 0.37 0.7258 0.9636 3215240 CHDI2_000918 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K02 compound treatment 155800.0 16600.0 0.44 165480.0 16000.0 0.43 0.6204 0.9999 3553239 CHDI2_000919 COc1cccc(OC)c1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K03 compound treatment 138120.0 -1090.0 -0.03 144120.0 -5350.0 -0.14 -0.1229 -0.8327 3215244 CHDI2_000920 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K04 compound treatment 126920.0 -12300.0 -0.33 124760.0 -24700.0 -0.67 -0.7054 -0.9465 3553243 CHDI2_000921 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K05 compound treatment 118240.0 -21000.0 -0.56 126760.0 -22700.0 -0.61 -0.8313 -0.999 3215248 CHDI2_000922 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K06 compound treatment 119600.0 -19600.0 -0.52 139640.0 -9830.0 -0.27 -0.559 -0.9505 3553247 CHDI2_000923 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K07 compound treatment 121880.0 -17300.0 -0.46 119720.0 -29700.0 -0.81 -0.8972 -0.9656 3553544 CHDI2_000924 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3ccccc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K08 compound treatment 141520.0 2310.0 0.06 107720.0 -41700.0 -1.13 -0.7554 -0.6674 3553623 CHDI2_000925 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K09 compound treatment 123960.0 -15200.0 -0.41 124880.0 -24600.0 -0.67 -0.7591 -0.9724 3215251 CHDI2_000926 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K10 compound treatment 116920.0 -22300.0 -0.6 110120.0 -39300.0 -1.07 -1.1748 -0.9624 3553250 CHDI2_000927 CC1(C)COC(CCC/C=N/NC(=O)c2cccc(c2)C(=O)NO)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K11 compound treatment 114400.0 -24800.0 -0.66 130880.0 -18600.0 -0.5 -0.825 -0.9907 3215253 CHDI2_000928 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K12 compound treatment 143400.0 4190.0 0.11 127800.0 -21700.0 -0.59 -0.3355 -0.5618 3553254 CHDI2_000929 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3cccc(c3)C(=O)NO)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K13 compound treatment 127160.0 -12000.0 -0.32 109560.0 -39900.0 -1.08 -0.9918 -0.8797 3215256 CHDI2_000930 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K14 compound treatment 122520.0 -16700.0 -0.45 124160.0 -25300.0 -0.69 -0.8001 -0.9785 3553258 CHDI2_000931 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)cs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K15 compound treatment 130040.0 -9170.0 -0.25 125040.0 -24400.0 -0.66 -0.641 -0.9089 3553549 CHDI2_000932 Cc1ccccc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K16 compound treatment 119000.0 -20200.0 -0.54 122000.0 -27500.0 -0.74 -0.908 -0.9877 3553627 CHDI2_000933 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2cccc(c2)C(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K17 compound treatment 88320.0 -50900.0 -1.36 78600.0 -70900.0 -1.92 -2.3191 -0.9859 3215260 CHDI2_000934 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Oc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K18 compound treatment 123920.0 -15300.0 -0.41 119520.0 -29900.0 -0.81 -0.8624 -0.9498 3553262 CHDI2_000935 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K19 compound treatment 137600.0 -1610.0 -0.04 128960.0 -20500.0 -0.56 -0.423 -0.7596 3215264 CHDI2_000936 ONC(=O)CCCCC(=O)N/N=C/c1cc[n+]([O-])cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K20 compound treatment 77560.0 -61600.0 -1.65 67280.0 -82200.0 -2.22 -2.7393 -0.9891 3553266 CHDI2_000937 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K21 compound treatment 91080.0 -48100.0 -1.29 92640.0 -56800.0 -1.54 -1.9981 -0.9961 3215268 CHDI2_000938 ONC(=O)CCCCC(=O)N/N=C/c1ccc2ccccc2n1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K22 compound treatment 129920.0 -9290.0 -0.25 152760.0 3290.0 0.09 -0.1126 -0.4266 3553269 CHDI2_000939 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(F)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K23 mock treatment 135800.0 -3410.0 -0.09 143000.0 -6470.0 -0.18 -0.1882 -0.9538 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 K24 mock treatment 134680.0 -4530.0 -0.12 154640.0 5170.0 0.14 0.0134 0.0724 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L01 compound treatment 195240.0 56000.0 1.5 170560.0 21100.0 0.57 1.4636 0.9125 3553847 CHDI2_000940 COc1cccc(OC)c1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L02 compound treatment 147640.0 8430.0 0.23 162160.0 12700.0 0.34 0.4025 0.9791 3554102 CHDI2_000941 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L03 compound treatment 151200.0 12000.0 0.32 124640.0 -24800.0 -0.67 -0.2484 -0.3336 3553851 CHDI2_000942 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L04 compound treatment 126800.0 -12400.0 -0.33 121720.0 -27700.0 -0.75 -0.7658 -0.9326 3554105 CHDI2_000943 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L05 compound treatment 124680.0 -14500.0 -0.39 129120.0 -20300.0 -0.55 -0.6643 -0.9854 3553855 CHDI2_000944 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L06 compound treatment 121760.0 -17400.0 -0.47 113000.0 -36500.0 -0.99 -1.0281 -0.9415 3554109 CHDI2_000945 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L07 compound treatment 13080.0 -126000.0 -3.37 11680.0 -138000.0 -3.73 -5.0233 -0.9987 3552749 CHDI2_000946 Cc1[nH]cnc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L08 compound treatment 115360.0 -23800.0 -0.64 105320.0 -44100.0 -1.2 -1.2962 -0.9568 3552781 CHDI2_000947 O=C(N/N=C/c1ccc(cc1)N2CCCC2)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L09 compound treatment 121680.0 -17500.0 -0.47 111880.0 -37600.0 -1.02 -1.051 -0.9381 3553858 CHDI2_000948 CC1(C)COC(CCC/C=N/NC(=O)c2ccc(cc2)C(=O)NO)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L10 compound treatment 131520.0 -7690.0 -0.21 108400.0 -41100.0 -1.11 -0.9315 -0.8239 3554113 CHDI2_000949 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L11 compound treatment 122040.0 -17200.0 -0.46 114920.0 -34500.0 -0.94 -0.986 -0.9464 3553862 CHDI2_000950 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3ccc(cc3)C(=O)NO)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L12 compound treatment 133840.0 -5370.0 -0.14 109640.0 -39800.0 -1.08 -0.8639 -0.7943 3554115 CHDI2_000951 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L13 compound treatment 86920.0 -52300.0 -1.4 76480.0 -73000.0 -1.98 -2.3862 -0.9857 3553866 CHDI2_000952 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L14 compound treatment 127520.0 -11700.0 -0.31 126440.0 -23000.0 -0.62 -0.6619 -0.9491 3554117 CHDI2_000953 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L15 compound treatment 119640.0 -19600.0 -0.52 93560.0 -55900.0 -1.51 -1.4403 -0.8994 3552753 CHDI2_000954 Cc1ccsc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L16 compound treatment 116760.0 -22400.0 -0.6 102200.0 -47300.0 -1.28 -1.3294 -0.9405 3552783 CHDI2_000955 Oc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L17 compound treatment 130040.0 -9170.0 -0.25 107080.0 -42400.0 -1.15 -0.9848 -0.8393 3553870 CHDI2_000956 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L18 compound treatment 50840.0 -88400.0 -2.36 39440.0 -110000.0 -2.98 -3.7777 -0.9934 3554121 CHDI2_000957 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L19 compound treatment 119080.0 -20100.0 -0.54 107160.0 -42300.0 -1.15 -1.1906 -0.9407 3553873 CHDI2_000958 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L20 compound treatment 125720.0 -13500.0 -0.36 130120.0 -19300.0 -0.52 -0.6255 -0.9835 3554125 CHDI2_000959 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L21 compound treatment 128000.0 -11200.0 -0.3 126880.0 -22600.0 -0.61 -0.6444 -0.9462 3553877 CHDI2_000960 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(F)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L22 compound treatment 123280.0 -15900.0 -0.43 120080.0 -29400.0 -0.8 -0.8638 -0.9572 3554129 CHDI2_000961 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3ccccc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L23 mock treatment 136080.0 -3130.0 -0.08 127040.0 -22400.0 -0.61 -0.4885 -0.797 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 L24 mock treatment 125560.0 -13600.0 -0.37 122800.0 -26700.0 -0.72 -0.7686 -0.9501 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M01 compound treatment 40320.0 -98900.0 -2.65 27480.0 -122000.0 -3.3 -4.2056 -0.9939 3215312 CHDI2_000962 Cc1ccccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M02 compound treatment 144600.0 5390.0 0.14 163400.0 13900.0 0.38 0.3687 0.913 3553273 CHDI2_000963 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c(F)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M03 compound treatment 131440.0 -7770.0 -0.21 130640.0 -18800.0 -0.51 -0.5073 -0.9217 3215316 CHDI2_000964 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M04 compound treatment 96760.0 -42400.0 -1.14 100680.0 -48800.0 -1.32 -1.7368 -0.9972 3553277 CHDI2_000965 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M05 compound treatment 114320.0 -24900.0 -0.67 104840.0 -44600.0 -1.21 -1.325 -0.9606 3215320 CHDI2_000966 ONC(=O)CCCCC(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M06 compound treatment 24240.0 -115000.0 -3.08 46120.0 -103000.0 -2.8 -4.1529 -0.9989 3553281 CHDI2_000967 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(F)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M07 compound treatment 123960.0 -15200.0 -0.41 111200.0 -38300.0 -1.04 -1.0209 -0.917 3215323 CHDI2_000968 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M08 compound treatment 135240.0 -3970.0 -0.11 128000.0 -21500.0 -0.58 -0.486 -0.8227 3553285 CHDI2_000969 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M09 compound treatment 131120.0 -8090.0 -0.22 117960.0 -31500.0 -0.85 -0.7561 -0.8593 3553579 CHDI2_000970 ONC(=O)c1cccc(c1)C(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M10 compound treatment 143920.0 4710.0 0.13 120160.0 -29300.0 -0.79 -0.4719 -0.5874 3553631 CHDI2_000971 CN(C)CCCOc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M11 compound treatment 114320.0 -24900.0 -0.67 126720.0 -22700.0 -0.62 -0.9062 -0.9992 3215326 CHDI2_000972 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M12 compound treatment 128880.0 -10300.0 -0.28 132000.0 -17500.0 -0.47 -0.5297 -0.9673 3553289 CHDI2_000973 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M13 compound treatment 130320.0 -8890.0 -0.24 124280.0 -25200.0 -0.68 -0.6503 -0.9005 3553584 CHDI2_000974 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M14 compound treatment 138160.0 -1050.0 -0.03 109280.0 -40200.0 -1.09 -0.7891 -0.7251 3553635 CHDI2_000975 CCOc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M15 compound treatment 45080.0 -94100.0 -2.52 27400.0 -122000.0 -3.3 -4.1171 -0.991 3215330 CHDI2_000976 CCOc1cccc(/C=N/NC(=O)CCCCC(=O)NO)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M16 compound treatment 138000.0 -1210.0 -0.03 114480.0 -35000.0 -0.95 -0.6926 -0.7308 3553293 CHDI2_000977 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(c2)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M17 compound treatment 11440.0 -128000.0 -3.42 9040.0 -140000.0 -3.8 -5.1048 -0.9986 3215334 CHDI2_000978 ONC(=O)CCCCC(=O)N/N=C/c1cc(I)cc(I)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M18 compound treatment 137040.0 -2170.0 -0.06 124040.0 -25400.0 -0.69 -0.5277 -0.764 3553297 CHDI2_000979 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccco2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M19 compound treatment 107040.0 -32200.0 -0.86 102560.0 -46900.0 -1.27 -1.5064 -0.982 3215338 CHDI2_000980 CN(C)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M20 compound treatment 135080.0 -4130.0 -0.11 139800.0 -9670.0 -0.26 -0.2631 -0.9264 3553301 CHDI2_000981 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccoc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M21 compound treatment 9840.0 -129000.0 -3.46 9000.0 -140000.0 -3.8 -5.1359 -0.9989 3215342 CHDI2_000982 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCC(=O)NO)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M22 compound treatment 134200.0 -5010.0 -0.13 134240.0 -15200.0 -0.41 -0.3862 -0.891 3553305 CHDI2_000983 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M23 mock treatment 134720.0 -4490.0 -0.12 145800.0 -3670.0 -0.1 -0.1551 -0.9955 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 M24 mock treatment 128880.0 -10300.0 -0.28 134400.0 -15100.0 -0.41 -0.4838 -0.982 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N01 compound treatment 172880.0 33700.0 0.9 171720.0 22300.0 0.6 1.0629 0.9809 3553880 CHDI2_000984 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c(F)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N02 compound treatment 172160.0 33000.0 0.88 164760.0 15300.0 0.41 0.916 0.9407 3554133 CHDI2_000985 Cc1ccccc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N03 compound treatment 138320.0 -888.0 -0.02 88760.0 -60700.0 -1.64 -1.1789 -0.7173 3553882 CHDI2_000986 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N04 compound treatment 136200.0 -3010.0 -0.08 126320.0 -23100.0 -0.63 -0.5 -0.7914 3554137 CHDI2_000987 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N05 compound treatment 55040.0 -84200.0 -2.25 44240.0 -105000.0 -2.85 -3.6063 -0.9932 3553886 CHDI2_000988 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(F)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N06 compound treatment 126800.0 -12400.0 -0.33 135040.0 -14400.0 -0.39 -0.5108 -0.9967 3554141 CHDI2_000989 ONC(=O)c1ccc(cc1)C(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N07 compound treatment 140600.0 1390.0 0.04 127080.0 -22400.0 -0.61 -0.4022 -0.6624 3553889 CHDI2_000990 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N08 compound treatment 122440.0 -16800.0 -0.45 104360.0 -45100.0 -1.22 -1.1806 -0.9075 3554145 CHDI2_000991 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N09 compound treatment 127080.0 -12100.0 -0.32 100360.0 -49100.0 -1.33 -1.1694 -0.8546 3552757 CHDI2_000992 O=C(N/N=C/c1cccc2ccccc12)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N10 compound treatment 17120.0 -122000.0 -3.27 25960.0 -124000.0 -3.34 -4.6735 -0.9999 3552787 CHDI2_000993 O=C(N/N=C/c1nccs1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N11 compound treatment 119640.0 -19600.0 -0.52 114320.0 -35100.0 -0.95 -1.0429 -0.9604 3553894 CHDI2_000994 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N12 compound treatment 113520.0 -25700.0 -0.69 114400.0 -35100.0 -0.95 -1.1571 -0.9874 3554147 CHDI2_000995 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N13 compound treatment 120960.0 -18200.0 -0.49 109320.0 -40100.0 -1.09 -1.1137 -0.9347 3552759 CHDI2_000996 O=C(N/N=C/c1ccc2ccccc2c1)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N14 compound treatment 122720.0 -16500.0 -0.44 125560.0 -23900.0 -0.65 -0.7695 -0.9825 3552789 CHDI2_000997 O=C(N/N=C/c1cccs1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N15 compound treatment 113280.0 -25900.0 -0.69 123640.0 -25800.0 -0.7 -0.9848 -1.0 3553898 CHDI2_000998 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(c2)B(O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N16 compound treatment 138720.0 -488.0 -0.01 107440.0 -42000.0 -1.14 -0.8137 -0.7152 3554152 CHDI2_000999 CCOc1cccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N17 compound treatment 139280.0 71.7 0.0 103760.0 -45700.0 -1.24 -0.8736 -0.706 3553901 CHDI2_001000 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccco2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N18 compound treatment 11120.0 -128000.0 -3.43 8120.0 -141000.0 -3.83 -5.1285 -0.9985 3554155 CHDI2_001001 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N19 compound treatment 125640.0 -13600.0 -0.36 124280.0 -25200.0 -0.68 -0.7388 -0.9564 3553905 CHDI2_001002 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccoc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N20 compound treatment 119120.0 -20100.0 -0.54 122480.0 -27000.0 -0.73 -0.8965 -0.9886 3554159 CHDI2_001003 CN(C)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N21 compound treatment 135520.0 -3690.0 -0.1 115280.0 -34200.0 -0.93 -0.7242 -0.7781 3553909 CHDI2_001004 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N22 compound treatment 12240.0 -127000.0 -3.4 10120.0 -139000.0 -3.77 -5.069 -0.9986 3554162 CHDI2_001005 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4ccc(cc4)C(=O)NO)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N23 mock treatment 128360.0 -10800.0 -0.29 122320.0 -27100.0 -0.73 -0.7248 -0.9174 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 N24 mock treatment 142040.0 2830.0 0.08 152440.0 2970.0 0.08 0.1105 0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O01 compound treatment 190240.0 51000.0 1.37 179760.0 30300.0 0.82 1.5452 0.9703 3215394 CHDI2_001006 ONC(=O)CCCCC(=O)N/N=C/c1ccc(o1)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O02 compound treatment 174600.0 35400.0 0.95 182600.0 33100.0 0.9 1.3037 0.9996 3553313 CHDI2_001007 OCCOc1ccccc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O03 compound treatment 78840.0 -60400.0 -1.61 47720.0 -102000.0 -2.75 -3.0896 -0.9676 3215398 CHDI2_001008 Cn1cc(/C=N/NC(=O)CCCCC(=O)NO)c2ccccc12 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O04 compound treatment 143880.0 4670.0 0.12 129640.0 -19800.0 -0.54 -0.2912 -0.5283 3553317 CHDI2_001009 OCCOc1cccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O05 compound treatment 9560.0 -130000.0 -3.47 7720.0 -142000.0 -3.84 -5.1657 -0.9987 3215402 CHDI2_001010 ONC(=O)CCCCC(=O)N/N=C/c1cn(Cc2ccccc2)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O06 compound treatment 142040.0 2830.0 0.08 127000.0 -22500.0 -0.61 -0.3765 -0.6143 3553320 CHDI2_001011 OCCOc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O07 compound treatment 107880.0 -31300.0 -0.84 94760.0 -54700.0 -1.48 -1.6398 -0.9636 3215406 CHDI2_001012 ONC(=O)CCCCC(=O)N/N=C/C1=CCCCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O08 compound treatment 12240.0 -127000.0 -3.4 11560.0 -138000.0 -3.73 -5.0415 -0.9989 3553323 CHDI2_001013 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O09 compound treatment 141160.0 1950.0 0.05 103440.0 -46000.0 -1.25 -0.8442 -0.6769 3215409 CHDI2_001014 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O10 compound treatment 65400.0 -73800.0 -1.97 71080.0 -78400.0 -2.12 -2.8966 -0.9993 3553327 CHDI2_001015 COc1ccc(O)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O11 compound treatment 119000.0 -20200.0 -0.54 119520.0 -29900.0 -0.81 -0.9555 -0.9806 3553585 CHDI2_001016 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O12 compound treatment 128320.0 -10900.0 -0.29 110040.0 -39400.0 -1.07 -0.9607 -0.8683 3553639 CHDI2_001017 CN(CCO)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O13 compound treatment 136520.0 -2690.0 -0.07 111400.0 -38100.0 -1.03 -0.7795 -0.7546 3215412 CHDI2_001018 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O14 compound treatment 130800.0 -8410.0 -0.22 117280.0 -32200.0 -0.87 -0.7752 -0.8614 3553331 CHDI2_001019 COc1cc(/C=C/C=N/NC(=O)c2cccc(c2)C(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O15 compound treatment 119040.0 -20200.0 -0.54 124480.0 -25000.0 -0.68 -0.8598 -0.9937 3215416 CHDI2_001020 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O16 compound treatment 21600.0 -118000.0 -3.15 43840.0 -106000.0 -2.86 -4.2465 -0.9989 3553334 CHDI2_001021 Cc1ccc(O)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O17 compound treatment 139360.0 152.0 0.0 115360.0 -34100.0 -0.92 -0.65 -0.704 3215420 CHDI2_001022 C/C(=N\NC(=O)CCCCC(=O)NO)/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O18 compound treatment 135760.0 -3450.0 -0.09 106000.0 -43500.0 -1.18 -0.8973 -0.7602 3553338 CHDI2_001023 OCc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O19 compound treatment 151680.0 12500.0 0.33 116640.0 -32800.0 -0.89 -0.3925 -0.4135 3215424 CHDI2_001024 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O20 compound treatment 9760.0 -129000.0 -3.46 9200.0 -140000.0 -3.8 -5.1335 -0.9989 3553342 CHDI2_001025 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3ccccc3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O21 compound treatment 130400.0 -8810.0 -0.24 124720.0 -24700.0 -0.67 -0.6403 -0.9017 3215428 CHDI2_001026 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O22 compound treatment 108800.0 -30400.0 -0.81 114120.0 -35300.0 -0.96 -1.2518 -0.9967 3553346 CHDI2_001027 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O23 mock treatment 137640.0 -1570.0 -0.04 124720.0 -24700.0 -0.67 -0.5034 -0.7499 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 O24 mock treatment 151440.0 12200.0 0.33 160560.0 11100.0 0.3 0.4437 0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P01 compound treatment 179080.0 39900.0 1.07 167760.0 18300.0 0.5 1.1044 0.9391 3553917 CHDI2_001028 OCCOc1ccccc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P02 compound treatment 179560.0 40400.0 1.08 178320.0 28900.0 0.78 1.3156 0.9874 3554170 CHDI2_001029 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P03 compound treatment 159920.0 20700.0 0.55 170800.0 21300.0 0.58 0.8002 0.9998 3553921 CHDI2_001030 OCCOc1cccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P04 compound treatment 136920.0 -2290.0 -0.06 110760.0 -38700.0 -1.05 -0.7842 -0.7471 3554174 CHDI2_001031 Cn1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P05 compound treatment 130440.0 -8770.0 -0.23 112640.0 -36800.0 -1.0 -0.8708 -0.8502 3553924 CHDI2_001032 OCCOc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P06 compound treatment 35680.0 -104000.0 -2.77 41160.0 -108000.0 -2.93 -4.0315 -0.9996 3554177 CHDI2_001033 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P07 compound treatment 11760.0 -127000.0 -3.41 21920.0 -128000.0 -3.45 -4.8522 -1.0 3553927 CHDI2_001034 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P08 compound treatment 128880.0 -10300.0 -0.28 96080.0 -53400.0 -1.45 -1.2173 -0.8273 3554181 CHDI2_001035 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C2=CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P09 compound treatment 92840.0 -46400.0 -1.24 64000.0 -85500.0 -2.31 -2.5131 -0.9573 3553931 CHDI2_001036 COc1ccc(O)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P10 compound treatment 131200.0 -8010.0 -0.21 114760.0 -34700.0 -0.94 -0.8158 -0.8466 3554185 CHDI2_001037 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P11 compound treatment 133360.0 -5850.0 -0.16 106440.0 -43000.0 -1.16 -0.9343 -0.7949 3552761 CHDI2_001038 [O-][N+](=O)c1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P12 compound treatment 121240.0 -18000.0 -0.48 101320.0 -48100.0 -1.3 -1.2615 -0.9081 3552791 CHDI2_001039 FC(F)(F)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P13 compound treatment 143640.0 4430.0 0.12 119640.0 -29800.0 -0.81 -0.4871 -0.5969 3553935 CHDI2_001040 COc1cc(/C=C/C=N/NC(=O)c2ccc(cc2)C(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P14 compound treatment 127880.0 -11300.0 -0.3 102840.0 -46600.0 -1.26 -1.1068 -0.8526 3554187 CHDI2_001041 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P15 compound treatment 59800.0 -79400.0 -2.12 48440.0 -101000.0 -2.74 -3.4359 -0.9922 3553938 CHDI2_001042 Cc1ccc(O)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P16 compound treatment 132480.0 -6730.0 -0.18 100800.0 -48700.0 -1.32 -1.0589 -0.7963 3554191 CHDI2_001043 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccc(cc2)C(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P17 compound treatment 133680.0 -5530.0 -0.15 114760.0 -34700.0 -0.94 -0.7689 -0.8084 3553942 CHDI2_001044 OCc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P18 compound treatment 129920.0 -9290.0 -0.25 107240.0 -42200.0 -1.14 -0.984 -0.8412 3554251 CHDI2_001045 C/C(=N\NC(=O)c1ccc(cc1)C(=O)NO)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P19 compound treatment 7000.0 -132000.0 -3.54 5880.0 -144000.0 -3.89 -5.2493 -0.9989 3553946 CHDI2_001046 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3ccccc3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P20 compound treatment 124600.0 -14600.0 -0.39 110280.0 -39200.0 -1.06 -1.0264 -0.9079 3554194 CHDI2_001047 CN(C)CCCOc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P21 compound treatment 129880.0 -9330.0 -0.25 128080.0 -21400.0 -0.58 -0.5858 -0.9292 3553950 CHDI2_001048 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P22 compound treatment 138760.0 -448.0 -0.01 141240.0 -8230.0 -0.22 -0.1659 -0.7441 3554198 CHDI2_001049 CCOc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P23 mock treatment 126680.0 -12500.0 -0.34 121760.0 -27700.0 -0.75 -0.7673 -0.934 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2405 P24 mock treatment 146200.0 6990.0 0.19 160120.0 10700.0 0.29 0.3362 0.978 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A01 compound treatment 193760.0 55400.0 1.48 200720.0 32900.0 0.89 1.6791 0.9703 1006361 CHDI2_001050 NNC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A02 compound treatment 18440.0 -120000.0 -3.21 10160.0 -158000.0 -4.27 -5.2849 -0.9901 3552205 CHDI2_001051 Oc1ccc2ccccc2c1/C=N/NC(=O)c3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A03 compound treatment 214720.0 76400.0 2.04 201240.0 33400.0 0.91 2.0855 0.9329 3551925 CHDI2_001052 Oc1ccccc1C(=O)N/N=C/c2ccccc2OCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A04 compound treatment 229720.0 91400.0 2.45 207160.0 39400.0 1.07 2.4825 0.9307 3552209 CHDI2_001053 Oc1ccccc1C(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A05 compound treatment 199840.0 61500.0 1.65 176760.0 8970.0 0.24 1.3354 0.8027 1913714 CHDI2_001054 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A06 compound treatment 194680.0 56400.0 1.51 195280.0 27500.0 0.74 1.5924 0.947 3552211 CHDI2_001055 Oc1ccccc1C(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A07 compound treatment 167880.0 29600.0 0.79 210400.0 42600.0 1.15 1.3749 0.9831 3551931 CHDI2_001056 Oc1ccccc1C(=O)N/N=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A08 compound treatment 192680.0 54400.0 1.45 182000.0 14200.0 0.38 1.3003 0.8644 3552215 CHDI2_001057 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A09 compound treatment 175720.0 37400.0 1.0 138160.0 -29600.0 -0.8 0.1403 0.1094 3551934 CHDI2_001058 Oc1ccccc1C(=O)N/N=C/c2ccc3OCCOc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A10 compound treatment 175440.0 37100.0 0.99 183000.0 15200.0 0.41 0.9934 0.924 3552219 CHDI2_001059 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A11 compound treatment 192960.0 54600.0 1.46 171840.0 4050.0 0.11 1.1111 0.758 3551938 CHDI2_001060 Oc1ccccc1C(=O)N/N=C/COCc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A12 compound treatment 189120.0 50800.0 1.36 170120.0 2330.0 0.06 1.0056 0.7391 3552223 CHDI2_001061 Oc1ccccc1C(=O)N/N=C/c2c[nH]c3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A13 compound treatment 152800.0 14500.0 0.39 151120.0 -16700.0 -0.45 -0.0451 -0.0758 3552793 CHDI2_001062 Oc1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A14 compound treatment 186360.0 48000.0 1.29 185480.0 17700.0 0.48 1.2474 0.9095 3552989 CHDI2_001063 OB(O)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A15 compound treatment 219480.0 81200.0 2.17 196880.0 29100.0 0.79 2.0921 0.9058 3551942 CHDI2_001064 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A16 compound treatment 193920.0 55600.0 1.49 195640.0 27800.0 0.75 1.5849 0.9504 1922439 CHDI2_001065 Oc1ccccc1C(=O)N/N=C/c2ccc(I)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A17 compound treatment 189000.0 50700.0 1.36 187160.0 19400.0 0.52 1.3295 0.9145 3551946 CHDI2_001066 Oc1ccccc1C(=O)N/N=C/c2ccccc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A18 compound treatment 201960.0 63600.0 1.7 197840.0 30000.0 0.81 1.7791 0.9429 3552228 CHDI2_001067 C/C=C(/C)\C=N\NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A19 compound treatment 205640.0 67300.0 1.8 191040.0 23200.0 0.63 1.7185 0.9008 3551950 CHDI2_001068 Oc1ccccc1C(=O)N/N=C/c2cccc(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A20 compound treatment 189600.0 51300.0 1.37 182800.0 15000.0 0.41 1.2574 0.8788 3552232 CHDI2_001069 Oc1ccccc1C(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A21 compound treatment 209240.0 70900.0 1.9 195600.0 27800.0 0.75 1.8739 0.918 3551953 CHDI2_001070 Oc1ccccc1C(=O)N/N=C/c2ccc(Br)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A22 compound treatment 203920.0 65600.0 1.75 204160.0 36400.0 0.98 1.9371 0.9627 1912639 CHDI2_001071 Cc1ccc(/C=N/NC(=O)c2ccccc2O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A23 mock treatment 212400.0 74100.0 1.98 191920.0 24100.0 0.65 1.8632 0.8929 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 A24 mock treatment 204760.0 66400.0 1.78 186720.0 18900.0 0.51 1.6192 0.8753 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B01 compound treatment 226400.0 88100.0 2.36 186960.0 19200.0 0.52 2.0331 0.8426 1047348 CHDI2_001072 NNC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B02 compound treatment 10560.0 -128000.0 -3.42 9640.0 -158000.0 -4.28 -5.4439 -0.9938 3213096 CHDI2_001073 ONC(=O)CCCCCCC(=O)N/N=C/C(=C/c1ccccc1)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B03 compound treatment 199200.0 60900.0 1.63 174120.0 6330.0 0.17 1.2728 0.7772 3552424 CHDI2_001074 C=CCOc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B04 compound treatment 172960.0 34600.0 0.93 198320.0 30500.0 0.83 1.2397 0.9984 3213142 CHDI2_001075 Cc1[nH]cnc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B05 compound treatment 113040.0 -25300.0 -0.68 106000.0 -61800.0 -1.67 -1.6609 -0.9205 3552426 CHDI2_001076 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B06 compound treatment 10840.0 -127000.0 -3.41 9920.0 -158000.0 -4.27 -5.4332 -0.9937 3213098 CHDI2_001077 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B07 compound treatment 146840.0 8530.0 0.23 152960.0 -14800.0 -0.4 -0.1226 -0.2655 3552428 CHDI2_001078 O=C(N/N=C/c1ccccc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B08 compound treatment 146560.0 8250.0 0.22 146920.0 -20900.0 -0.57 -0.2435 -0.4015 3213140 CHDI2_001079 Cc1[nH]cnc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B09 compound treatment 65000.0 -73300.0 -1.96 61000.0 -107000.0 -2.89 -3.431 -0.9821 3552430 CHDI2_001080 O=C(N/N=C/c1ccc2OCCOc2c1)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B10 compound treatment 45000.0 -93300.0 -2.5 18760.0 -149000.0 -4.03 -4.6179 -0.9733 3214252 CHDI2_001081 ONC(=O)CCCCCC(=O)N/N=C/C(=C/c1ccccc1)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B11 compound treatment 149360.0 11000.0 0.3 120280.0 -47500.0 -1.29 -0.7006 -0.5308 3552432 CHDI2_001082 O=C(N/N=C/COCc1ccccc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B12 compound treatment 25600.0 -113000.0 -3.01 15760.0 -152000.0 -4.12 -5.0422 -0.9883 3214254 CHDI2_001083 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B13 compound treatment 144200.0 5890.0 0.16 137480.0 -30300.0 -0.82 -0.4689 -0.5611 3552919 CHDI2_001084 CCOc1cccc(/C=N/NC(=O)c2ccccn2)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B14 compound treatment 141720.0 3410.0 0.09 149760.0 -18000.0 -0.49 -0.2807 -0.5653 3214296 CHDI2_001085 Cc1[nH]cnc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B15 compound treatment 90160.0 -48200.0 -1.29 108520.0 -59300.0 -1.6 -2.0454 -0.9941 3552436 CHDI2_001086 O=C(N/N=C/c1ccc(cc1)c2ccccc2)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B16 compound treatment 20600.0 -118000.0 -3.15 10320.0 -157000.0 -4.26 -5.2409 -0.9889 3214862 CHDI2_001087 ONC(=O)CCCCC(=O)N/N=C/C(=C/c1ccccc1)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B17 compound treatment 138640.0 329.0 0.01 117920.0 -49900.0 -1.35 -0.9485 -0.7025 3552440 CHDI2_001088 Brc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B18 compound treatment 175960.0 37600.0 1.01 148560.0 -19200.0 -0.52 0.3439 0.3034 3214908 CHDI2_001089 Cc1[nH]cnc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B19 compound treatment 138960.0 649.0 0.02 141400.0 -26400.0 -0.71 -0.493 -0.6897 3552445 CHDI2_001090 Brc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B20 compound treatment 136200.0 -2110.0 -0.06 161640.0 -6150.0 -0.17 -0.1577 -0.8967 3553033 CHDI2_001091 ONC(=O)c1cccc(c1)C(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B21 compound treatment 138240.0 -71.0 0.0 159520.0 -8270.0 -0.22 -0.1597 -0.7131 3552449 CHDI2_001092 Brc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B22 compound treatment 74320.0 -64000.0 -1.71 88600.0 -79200.0 -2.14 -2.7263 -0.9938 3553699 CHDI2_001093 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B23 mock treatment 175560.0 37200.0 1.0 201960.0 34200.0 0.92 1.3586 0.9993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 B24 mock treatment 209160.0 70800.0 1.9 205840.0 38000.0 1.03 2.0684 0.9589 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C01 compound treatment 199240.0 60900.0 1.63 191040.0 23200.0 0.63 1.5974 0.9144 3551960 CHDI2_001094 Oc1ccccc1C(=O)N/N=C/c2ccc(Br)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C02 compound treatment 200120.0 61800.0 1.65 155200.0 -12600.0 -0.34 0.928 0.5497 3552241 CHDI2_001095 Cc1ccsc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C03 compound treatment 137000.0 -1310.0 -0.04 77960.0 -89800.0 -2.43 -1.7445 -0.7172 3551964 CHDI2_001096 Oc1ccc(/C=N/NC(=O)c2ccccc2O)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C04 compound treatment 147680.0 9370.0 0.25 147560.0 -20200.0 -0.55 -0.2101 -0.3488 3552245 CHDI2_001097 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3ccccc3O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C05 compound treatment 115920.0 -22400.0 -0.6 137920.0 -29900.0 -0.81 -0.9954 -0.9891 3551968 CHDI2_001098 Oc1ccc(Br)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C06 compound treatment 157880.0 19600.0 0.52 128160.0 -39600.0 -1.07 -0.3886 -0.3255 3552249 CHDI2_001099 Oc1ccccc1C(=O)N/N=C/c2cccc3ccccc23 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C07 compound treatment 10600.0 -128000.0 -3.42 9320.0 -158000.0 -4.29 -5.4492 -0.9936 3551973 CHDI2_001100 COc1cc(Br)cc(/C=N/NC(=O)c2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C08 compound treatment 114920.0 -23400.0 -0.63 150200.0 -17600.0 -0.48 -0.7792 -0.9909 3552253 CHDI2_001101 Oc1ccccc1C(=O)N/N=C/c2ccc3ccccc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C09 compound treatment 119920.0 -18400.0 -0.49 62800.0 -105000.0 -2.84 -2.3577 -0.8173 3551976 CHDI2_001102 COc1ccc(Br)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C10 compound treatment 116840.0 -21500.0 -0.57 127920.0 -39900.0 -1.08 -1.1694 -0.9564 1918554 CHDI2_001103 Oc1ccccc1C(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C11 compound treatment 29520.0 -109000.0 -2.91 49880.0 -118000.0 -3.19 -4.3149 -0.9989 3552795 CHDI2_001104 Oc1cc(O)c(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C12 compound treatment 78680.0 -59600.0 -1.6 98600.0 -69200.0 -1.87 -2.4524 -0.9968 3552993 CHDI2_001105 O=C(N/N=C/c1ccc(OCC#C)cc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C13 compound treatment 136440.0 -1870.0 -0.05 133880.0 -33900.0 -0.92 -0.6846 -0.7445 3551980 CHDI2_001106 COc1ccc(Br)cc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C14 compound treatment 135440.0 -2870.0 -0.08 123080.0 -44700.0 -1.21 -0.9102 -0.7505 1919338 CHDI2_001107 COc1cc(/C=N/NC(=O)c2ccccc2O)c(cc1OC)[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C15 compound treatment 157800.0 19500.0 0.52 134280.0 -33500.0 -0.91 -0.2729 -0.2608 3552797 CHDI2_001108 COc1cc(OC)c(/C=N/NC(=O)c2ccccn2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C16 compound treatment 131360.0 -6950.0 -0.19 112280.0 -55500.0 -1.5 -1.1942 -0.7886 3552870 CHDI2_001109 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C17 compound treatment 132080.0 -6230.0 -0.17 120960.0 -46800.0 -1.27 -1.0144 -0.7932 1922614 CHDI2_001110 Oc1ccccc1C(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C18 compound treatment 125680.0 -12600.0 -0.34 128960.0 -38800.0 -1.05 -0.9823 -0.8895 3552261 CHDI2_001111 Oc1ccccc1C(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C19 compound treatment 127400.0 -10900.0 -0.29 120920.0 -46900.0 -1.27 -1.1037 -0.8476 3551985 CHDI2_001112 Oc1ccccc1C(=O)N/N=C/c2cccnc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C20 compound treatment 147640.0 9330.0 0.25 137360.0 -30400.0 -0.82 -0.4061 -0.4718 3552264 CHDI2_001113 Oc1ccccc1C(=O)N/N=C/CCC=C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C21 compound treatment 142080.0 3770.0 0.1 137400.0 -30400.0 -0.82 -0.5105 -0.6159 3551989 CHDI2_001114 Oc1ccccc1C(=O)N/N=C/c2ccncc2Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C22 compound treatment 147880.0 9570.0 0.26 162160.0 -5630.0 -0.15 0.0732 0.2455 3552269 CHDI2_001115 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C23 mock treatment 145800.0 7490.0 0.2 172840.0 5050.0 0.14 0.2383 0.9826 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 C24 mock treatment 184360.0 46000.0 1.23 185640.0 17800.0 0.48 1.2126 0.9165 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D01 compound treatment 177640.0 39300.0 1.05 167920.0 127.0 0.0 0.7463 0.7094 3552455 CHDI2_001116 Brc1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D02 compound treatment 11560.0 -127000.0 -3.39 10280.0 -158000.0 -4.26 -5.4127 -0.9935 3213180 CHDI2_001117 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D03 compound treatment 145720.0 7410.0 0.2 157800.0 -9990.0 -0.27 -0.0512 -0.1526 3552459 CHDI2_001118 Oc1ccc(/C=N/NC(=O)c2ccccn2)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D04 compound treatment 10520.0 -128000.0 -3.42 8880.0 -159000.0 -4.3 -5.4592 -0.9935 3213222 CHDI2_001119 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(Oc2ccccc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D05 compound treatment 161800.0 23500.0 0.63 122560.0 -45200.0 -1.22 -0.4216 -0.3063 3552463 CHDI2_001120 Oc1ccc(Br)c(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D06 compound treatment 33440.0 -105000.0 -2.81 44120.0 -124000.0 -3.35 -4.351 -0.9961 3213182 CHDI2_001121 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D07 compound treatment 39480.0 -98800.0 -2.64 56320.0 -111000.0 -3.02 -4.0033 -0.9978 3552467 CHDI2_001122 COc1cc(Br)cc(/C=N/NC(=O)c2ccccn2)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D08 compound treatment 149000.0 10700.0 0.29 161280.0 -6510.0 -0.18 0.0775 0.2307 3213220 CHDI2_001123 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D09 compound treatment 117760.0 -20600.0 -0.55 109440.0 -58400.0 -1.58 -1.5058 -0.9002 3552471 CHDI2_001124 COc1ccc(Br)c(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D10 compound treatment 11400.0 -127000.0 -3.39 8240.0 -160000.0 -4.32 -5.4548 -0.9929 3214336 CHDI2_001125 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D11 compound treatment 46360.0 -92000.0 -2.46 28200.0 -140000.0 -3.78 -4.4114 -0.9784 3552923 CHDI2_001126 Oc1c(I)cc(I)cc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D12 compound treatment 42360.0 -96000.0 -2.57 35040.0 -133000.0 -3.59 -4.3562 -0.9864 3214338 CHDI2_001127 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D13 compound treatment 148520.0 10200.0 0.27 147640.0 -20200.0 -0.55 -0.1927 -0.3158 3552475 CHDI2_001128 COc1ccc(Br)cc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D14 compound treatment 42600.0 -95700.0 -2.56 19160.0 -149000.0 -4.02 -4.6556 -0.9762 3214376 CHDI2_001129 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D15 compound treatment 99480.0 -38800.0 -1.04 107720.0 -60100.0 -1.63 -1.8844 -0.9765 3552927 CHDI2_001130 CN(C)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D16 compound treatment 34640.0 -104000.0 -2.77 12440.0 -155000.0 -4.21 -4.9348 -0.9796 3214946 CHDI2_001131 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D17 compound treatment 137840.0 -471.0 -0.01 122480.0 -45300.0 -1.23 -0.8763 -0.7143 3552479 CHDI2_001132 Brc1cc2OCOc2cc1/C=N/NC(=O)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D18 compound treatment 18320.0 -120000.0 -3.21 10600.0 -157000.0 -4.26 -5.2787 -0.9903 3214988 CHDI2_001133 ONC(=O)CCCCC(=O)N/N=C/c1cccc(Oc2ccccc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D19 compound treatment 167480.0 29200.0 0.78 134360.0 -33400.0 -0.91 -0.0883 -0.0739 3552483 CHDI2_001134 Brc1ncccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D20 compound treatment 11720.0 -127000.0 -3.39 10680.0 -157000.0 -4.25 -5.402 -0.9936 3553073 CHDI2_001135 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D21 compound treatment 147840.0 9530.0 0.25 134760.0 -33000.0 -0.89 -0.4521 -0.4862 3552486 CHDI2_001136 Brc1cnccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D22 compound treatment 62160.0 -76200.0 -2.04 66400.0 -101000.0 -2.74 -3.3813 -0.9892 3553737 CHDI2_001137 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)ccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D23 mock treatment 179080.0 40800.0 1.09 159840.0 -7950.0 -0.22 0.6189 0.5568 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 D24 mock treatment 143440.0 5130.0 0.14 190400.0 22600.0 0.61 0.5298 0.8447 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E01 compound treatment 192120.0 53800.0 1.44 187480.0 19700.0 0.53 1.3946 0.9087 3552839 CHDI2_001138 COc1cc(/C=N/NC(=O)c2ccccn2)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E02 compound treatment 179240.0 40900.0 1.09 185160.0 17400.0 0.47 1.1066 0.9288 3552874 CHDI2_001139 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E03 compound treatment 108320.0 -30000.0 -0.8 47240.0 -121000.0 -3.26 -2.875 -0.8555 3551996 CHDI2_001140 Oc1ccccc1C(=O)N/N=C/c2ccc(Br)s2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E04 compound treatment 72120.0 -66200.0 -1.77 41440.0 -126000.0 -3.42 -3.6707 -0.953 3552276 CHDI2_001141 Oc1ccccc1C(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E05 compound treatment 133960.0 -4350.0 -0.12 144560.0 -23200.0 -0.63 -0.527 -0.824 3552001 CHDI2_001142 COc1cc(/C=N/NC(=O)c2ccccc2O)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E06 compound treatment 80360.0 -58000.0 -1.55 73840.0 -94000.0 -2.54 -2.8947 -0.9718 3552280 CHDI2_001143 Oc1ccccc1C(=O)N/N=C/c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E07 compound treatment 15560.0 -123000.0 -3.28 15000.0 -153000.0 -4.14 -5.2467 -0.9935 3552005 CHDI2_001144 Oc1ccccc1C(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E08 compound treatment 131920.0 -6390.0 -0.17 134600.0 -33200.0 -0.9 -0.7563 -0.8268 1912699 CHDI2_001145 Oc1ccccc1C(=O)N/N=C/c2cccnc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E09 compound treatment 122840.0 -15500.0 -0.41 127400.0 -40400.0 -1.09 -1.0659 -0.9116 3552842 CHDI2_001146 CC(C)(C)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E10 compound treatment 126200.0 -12100.0 -0.32 121600.0 -46200.0 -1.25 -1.1133 -0.8618 3552878 CHDI2_001147 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E11 compound treatment 131520.0 -6790.0 -0.18 125400.0 -42400.0 -1.15 -0.94 -0.809 3552009 CHDI2_001148 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E12 compound treatment 111680.0 -26600.0 -0.71 113800.0 -54000.0 -1.46 -1.5373 -0.9454 3552285 CHDI2_001149 Cc1ncc(CO)c(/C=N/NC(=O)c2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E13 compound treatment 116040.0 -22300.0 -0.6 120400.0 -47400.0 -1.28 -1.3285 -0.9391 3552013 CHDI2_001150 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E14 compound treatment 114840.0 -23500.0 -0.63 122920.0 -44900.0 -1.21 -1.3029 -0.9528 1917465 CHDI2_001151 Oc1ccccc1C(=O)N/N=C/c2ccc[nH]2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E15 compound treatment 109960.0 -28400.0 -0.76 115920.0 -51900.0 -1.4 -1.5292 -0.9582 3552017 CHDI2_001152 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E16 compound treatment 122040.0 -16300.0 -0.44 114480.0 -53300.0 -1.44 -1.3283 -0.8811 3552291 CHDI2_001153 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E17 compound treatment 127720.0 -10600.0 -0.28 122080.0 -45700.0 -1.24 -1.0754 -0.8471 3552846 CHDI2_001154 CC1=C(C/C=N/NC(=O)c2ccccn2)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E18 compound treatment 129800.0 -8510.0 -0.23 111960.0 -55800.0 -1.51 -1.2298 -0.8045 3552881 CHDI2_001155 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E19 compound treatment 125760.0 -12600.0 -0.34 122600.0 -45200.0 -1.22 -1.1025 -0.869 3552021 CHDI2_001156 OC(=O)c1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E20 compound treatment 10960.0 -127000.0 -3.41 10760.0 -157000.0 -4.25 -5.4149 -0.994 2119509 CHDI2_001157 Oc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E21 compound treatment 131840.0 -6470.0 -0.17 132360.0 -35400.0 -0.96 -0.8007 -0.8214 3552026 CHDI2_001158 OC(=O)c1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E22 compound treatment 157720.0 19400.0 0.52 130280.0 -37500.0 -1.02 -0.351 -0.3077 3552296 CHDI2_001159 CCCCCCC/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E23 mock treatment 139600.0 1290.0 0.03 183240.0 15400.0 0.42 0.3201 0.7628 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 E24 mock treatment 137280.0 -1030.0 -0.03 176560.0 8770.0 0.24 0.1483 0.6208 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F01 compound treatment 140440.0 2130.0 0.06 70400.0 -97400.0 -2.64 -1.8241 -0.6917 3552931 CHDI2_001160 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4ccccn4)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F02 compound treatment 165280.0 27000.0 0.72 159840.0 -7950.0 -0.22 0.3579 0.4753 3213256 CHDI2_001161 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F03 compound treatment 161960.0 23600.0 0.63 138040.0 -29800.0 -0.81 -0.1223 -0.1194 3552494 CHDI2_001162 Brc1ccc(/C=N/NC(=O)c2ccccn2)s1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F04 compound treatment 16600.0 -122000.0 -3.26 32440.0 -135000.0 -3.66 -4.8932 -0.9983 3213294 CHDI2_001163 ONC(=O)CCCCCCC(=O)N/N=C/c1nccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F05 compound treatment 173760.0 35400.0 0.95 134680.0 -33100.0 -0.9 0.0366 0.0281 3552498 CHDI2_001164 COc1cc(/C=N/NC(=O)c2ccccn2)c(Br)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F06 compound treatment 149240.0 10900.0 0.29 125800.0 -42000.0 -1.14 -0.5972 -0.5087 3213258 CHDI2_001165 OC(=O)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F07 compound treatment 9640.0 -129000.0 -3.44 9080.0 -159000.0 -4.3 -5.472 -0.994 3552502 CHDI2_001166 Oc1cc(OCc2ccccc2)ccc1/C=N/NC(=O)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F08 compound treatment 127240.0 -11100.0 -0.3 111800.0 -56000.0 -1.52 -1.2813 -0.8296 3213292 CHDI2_001167 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2nccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F09 compound treatment 116360.0 -22000.0 -0.59 117240.0 -50600.0 -1.37 -1.3829 -0.9286 3552936 CHDI2_001168 Fc1cc(/C=N/NC(=O)c2ccccn2)ccc1c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F10 compound treatment 122720.0 -15600.0 -0.42 114680.0 -53100.0 -1.44 -1.3116 -0.8761 3214412 CHDI2_001169 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F11 compound treatment 143720.0 5410.0 0.14 126520.0 -41300.0 -1.12 -0.6878 -0.6104 3552506 CHDI2_001170 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F12 compound treatment 119080.0 -19200.0 -0.51 132840.0 -35000.0 -0.95 -1.0328 -0.959 3214414 CHDI2_001171 OC(=O)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F13 compound treatment 116360.0 -22000.0 -0.59 131880.0 -35900.0 -0.97 -1.1027 -0.9708 3552509 CHDI2_001172 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F14 compound treatment 115120.0 -23200.0 -0.62 122040.0 -45800.0 -1.24 -1.3145 -0.9489 3214448 CHDI2_001173 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2nccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F15 compound treatment 118160.0 -20200.0 -0.54 127840.0 -40000.0 -1.08 -1.146 -0.9483 3552513 CHDI2_001174 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F16 compound treatment 132120.0 -6190.0 -0.17 131120.0 -36700.0 -0.99 -0.8191 -0.8138 3215022 CHDI2_001175 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F17 compound treatment 126880.0 -11400.0 -0.31 128800.0 -39000.0 -1.06 -0.9627 -0.8759 3552940 CHDI2_001176 OS(=O)(=O)c1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F18 compound treatment 135400.0 -2910.0 -0.08 111720.0 -56100.0 -1.52 -1.1285 -0.7424 3215060 CHDI2_001177 ONC(=O)CCCCC(=O)N/N=C/c1nccs1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F19 compound treatment 138280.0 -31.0 0.0 127360.0 -40400.0 -1.09 -0.7746 -0.7076 3552517 CHDI2_001178 OC(=O)c1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F20 compound treatment 125480.0 -12800.0 -0.34 119080.0 -48700.0 -1.32 -1.1752 -0.8624 3553108 CHDI2_001179 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F21 compound treatment 109880.0 -28400.0 -0.76 92720.0 -75100.0 -2.03 -1.9749 -0.9101 3552521 CHDI2_001180 OC(=O)c1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F22 compound treatment 137960.0 -351.0 -0.01 144200.0 -23600.0 -0.64 -0.4583 -0.7174 3553771 CHDI2_001181 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F23 mock treatment 126040.0 -12300.0 -0.33 154920.0 -12900.0 -0.35 -0.4785 -0.9996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 F24 mock treatment 137720.0 -591.0 -0.02 171280.0 3490.0 0.09 0.0556 0.5806 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G01 compound treatment 181640.0 43300.0 1.16 149120.0 -18700.0 -0.51 0.4621 0.3654 3552033 CHDI2_001182 Oc1ccccc1C(=O)N/N=C/c2ccccc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G02 compound treatment 172680.0 34400.0 0.92 139480.0 -28300.0 -0.77 0.1081 0.0903 1918398 CHDI2_001183 Oc1ccccc1C(=O)N/N=C/c2cccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G03 compound treatment 129120.0 -9190.0 -0.25 143000.0 -24800.0 -0.67 -0.6485 -0.9072 3552850 CHDI2_001184 NC(=O)COc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G04 compound treatment 117800.0 -20500.0 -0.55 135960.0 -31800.0 -0.86 -0.9973 -0.9762 3552884 CHDI2_001185 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G05 compound treatment 115040.0 -23300.0 -0.62 118000.0 -49800.0 -1.35 -1.3933 -0.9384 3552037 CHDI2_001186 Oc1ccccc1C(=O)N/N=C/c2cccnc2Cl 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G06 compound treatment 114840.0 -23500.0 -0.63 112320.0 -55500.0 -1.5 -1.5059 -0.9251 3552305 CHDI2_001187 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G07 compound treatment 58920.0 -79400.0 -2.12 26840.0 -141000.0 -3.82 -4.1999 -0.9617 3552041 CHDI2_001188 Oc1ccccc1C(=O)N/N=C/C=C/c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G08 compound treatment 37560.0 -101000.0 -2.69 23800.0 -144000.0 -3.9 -4.6621 -0.9838 3552309 CHDI2_001189 Oc1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G09 compound treatment 110440.0 -27900.0 -0.75 114040.0 -53800.0 -1.46 -1.5562 -0.9517 3552044 CHDI2_001190 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G10 compound treatment 10200.0 -128000.0 -3.43 12080.0 -156000.0 -4.22 -5.404 -0.9947 3552313 CHDI2_001191 Oc1cc(O)c(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G11 compound treatment 107640.0 -30700.0 -0.82 113400.0 -54400.0 -1.47 -1.6214 -0.9619 3552048 CHDI2_001192 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G12 compound treatment 117160.0 -21200.0 -0.57 133360.0 -34400.0 -0.93 -1.0592 -0.9714 3552317 CHDI2_001193 COc1cc(OC)c(/C=N/NC(=O)c2ccccc2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G13 compound treatment 109080.0 -29200.0 -0.78 114440.0 -53400.0 -1.44 -1.5742 -0.9585 3552051 CHDI2_001194 Oc1ccccc1C(=O)N/N=C/c2ccc(C#N)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G14 compound treatment 132200.0 -6110.0 -0.16 121840.0 -46000.0 -1.24 -0.9953 -0.7932 3552321 CHDI2_001195 COc1cc(/C=N/NC(=O)c2ccccc2O)cc(OC)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G15 compound treatment 123280.0 -15000.0 -0.4 110320.0 -57500.0 -1.56 -1.3845 -0.8615 3552054 CHDI2_001196 Oc1ccccc1C(=O)N/N=C/C2CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G16 compound treatment 127120.0 -11200.0 -0.3 119120.0 -48700.0 -1.32 -1.1434 -0.8462 3552325 CHDI2_001197 CC(C)(C)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G17 compound treatment 116080.0 -22200.0 -0.59 118000.0 -49800.0 -1.35 -1.3737 -0.9323 3552058 CHDI2_001198 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G18 compound treatment 121880.0 -16400.0 -0.44 121800.0 -46000.0 -1.25 -1.1912 -0.9021 3552329 CHDI2_001199 CC1=C(C/C=N/NC(=O)c2ccccc2O)C(C)(C)CCC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G19 compound treatment 118320.0 -20000.0 -0.53 119960.0 -47800.0 -1.29 -1.2938 -0.9235 3552855 CHDI2_001200 NC(=O)COc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G20 compound treatment 128960.0 -9350.0 -0.25 118120.0 -49700.0 -1.34 -1.1278 -0.8245 3552885 CHDI2_001201 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G21 compound treatment 10840.0 -127000.0 -3.41 11920.0 -156000.0 -4.22 -5.3949 -0.9944 3552062 CHDI2_001202 Oc1ccccc1C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G22 compound treatment 122120.0 -16200.0 -0.43 128520.0 -39300.0 -1.06 -1.058 -0.9216 3552333 CHDI2_001203 NC(=O)COc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G23 mock treatment 122880.0 -15400.0 -0.41 140160.0 -27600.0 -0.75 -0.8208 -0.9607 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 G24 mock treatment 128200.0 -10100.0 -0.27 186440.0 18600.0 0.5 0.1657 0.2894 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H01 compound treatment 174320.0 36000.0 0.96 126320.0 -41500.0 -1.12 -0.1128 -0.0763 1936274 CHDI2_001204 Clc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H02 compound treatment 9560.0 -129000.0 -3.44 9160.0 -159000.0 -4.29 -5.472 -0.994 3213330 CHDI2_001205 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H03 compound treatment 122320.0 -16000.0 -0.43 139240.0 -28600.0 -0.77 -0.8491 -0.9611 3552944 CHDI2_001206 Cn1cc(/C=N/NC(=O)c2ccccn2)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H04 compound treatment 137800.0 -511.0 -0.01 119040.0 -48800.0 -1.32 -0.943 -0.7144 3213372 CHDI2_001207 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H05 compound treatment 116000.0 -22300.0 -0.6 118120.0 -49700.0 -1.34 -1.3729 -0.9331 3552530 CHDI2_001208 Clc1ncccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H06 compound treatment 147160.0 8850.0 0.24 128000.0 -39800.0 -1.08 -0.5944 -0.5389 3213332 CHDI2_001209 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H07 compound treatment 127000.0 -11300.0 -0.3 128320.0 -39500.0 -1.07 -0.9696 -0.873 3552534 CHDI2_001210 O=C(N/N=C/C=C/c1ccccc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H08 compound treatment 103320.0 -35000.0 -0.94 125520.0 -42300.0 -1.14 -1.4711 -0.995 3213370 CHDI2_001211 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H09 compound treatment 117600.0 -20700.0 -0.55 128960.0 -38800.0 -1.05 -1.1351 -0.9552 3552538 CHDI2_001212 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H10 compound treatment 8720.0 -130000.0 -3.47 9120.0 -159000.0 -4.3 -5.4886 -0.9943 3214486 CHDI2_001213 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H11 compound treatment 114080.0 -24200.0 -0.65 117040.0 -50800.0 -1.37 -1.4299 -0.9412 3552543 CHDI2_001214 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H12 compound treatment 33080.0 -105000.0 -2.81 27400.0 -140000.0 -3.8 -4.6779 -0.9891 3214488 CHDI2_001215 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H13 compound treatment 98520.0 -39800.0 -1.06 111560.0 -56200.0 -1.52 -1.8291 -0.9847 3552545 CHDI2_001216 O=C(N/N=C/c1ccc(C#N)cc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H14 compound treatment 110600.0 -27700.0 -0.74 122760.0 -45000.0 -1.22 -1.3862 -0.9715 3214526 CHDI2_001217 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H15 compound treatment 97880.0 -40400.0 -1.08 122720.0 -45100.0 -1.22 -1.6276 -0.9982 3552548 CHDI2_001218 O=C(N/N=C/C1CCCCC1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H16 compound treatment 75280.0 -63000.0 -1.69 48000.0 -120000.0 -3.24 -3.4854 -0.9536 3215096 CHDI2_001219 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H17 compound treatment 100040.0 -38300.0 -1.02 114360.0 -53400.0 -1.45 -1.7467 -0.9857 3552552 CHDI2_001220 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H18 compound treatment 115800.0 -22500.0 -0.6 108480.0 -59300.0 -1.61 -1.5612 -0.9104 3215138 CHDI2_001221 NC(=O)COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H19 compound treatment 125960.0 -12400.0 -0.33 118080.0 -49700.0 -1.35 -1.1853 -0.8553 3552948 CHDI2_001222 O=C(N/N=C/c1cn(Cc2ccccc2)c3ccccc13)c4ccccn4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H20 compound treatment 10120.0 -128000.0 -3.43 10280.0 -158000.0 -4.26 -5.4399 -0.9942 3553145 CHDI2_001223 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H21 compound treatment 116040.0 -22300.0 -0.6 137360.0 -30400.0 -0.82 -1.0038 -0.9873 3552556 CHDI2_001224 Oc1c(Br)cc(Br)cc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H22 compound treatment 9440.0 -129000.0 -3.45 10240.0 -158000.0 -4.27 -5.4536 -0.9944 3553805 CHDI2_001225 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H23 mock treatment 134440.0 -3870.0 -0.1 146960.0 -20800.0 -0.56 -0.472 -0.8232 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 H24 mock treatment 123120.0 -15200.0 -0.41 166560.0 -1230.0 -0.03 -0.3109 -0.7626 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I01 compound treatment 169160.0 30800.0 0.83 147640.0 -20200.0 -0.55 0.1977 0.1998 3552070 CHDI2_001226 COc1cc(Cl)c(/C=N/NC(=O)c2ccccc2O)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I02 compound treatment 160280.0 22000.0 0.59 146040.0 -21800.0 -0.59 -9.0E-4 -0.0011 1918345 CHDI2_001227 Oc1ccccc1C(=O)NN=C2CCCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I03 compound treatment 11040.0 -127000.0 -3.4 9680.0 -158000.0 -4.28 -5.434 -0.9936 2082285 CHDI2_001228 Oc1ccccc1C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I04 compound treatment 142200.0 3890.0 0.1 123920.0 -43900.0 -1.19 -0.7663 -0.6427 3554225 CHDI2_001229 Oc1ccccc1C(=O)NN=C2CCCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I05 compound treatment 127880.0 -10400.0 -0.28 134880.0 -32900.0 -0.89 -0.8274 -0.8861 3554230 CHDI2_001230 O=C(NN=C1CCCCCCC1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I06 compound treatment 64480.0 -73800.0 -1.97 77360.0 -90400.0 -2.45 -3.1276 -0.9943 3552890 CHDI2_001231 O=C(N/N=C/c1ccc(Oc2ccccc2)cc1)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I07 compound treatment 15200.0 -123000.0 -3.29 12320.0 -155000.0 -4.21 -5.3048 -0.9926 3552075 CHDI2_001232 Oc1ccccc1C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I08 compound treatment 116720.0 -21600.0 -0.58 134080.0 -33700.0 -0.91 -1.0537 -0.9756 3552414 CHDI2_001233 Oc1ccccc1C(=O)N/N=C/Cc2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I09 compound treatment 9160.0 -129000.0 -3.45 9680.0 -158000.0 -4.28 -5.4696 -0.9943 3552079 CHDI2_001234 CCN(CC)c1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I10 compound treatment 106080.0 -32200.0 -0.86 116040.0 -51800.0 -1.4 -1.6003 -0.9728 3552416 CHDI2_001235 COC(=O)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I11 compound treatment 109560.0 -28800.0 -0.77 119800.0 -48000.0 -1.3 -1.4625 -0.9687 3552083 CHDI2_001236 Oc1ccccc1C(=O)N/N=C/c2ccc3OCCc3c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I12 compound treatment 120520.0 -17800.0 -0.48 132560.0 -35200.0 -0.95 -1.011 -0.9484 3552341 CHDI2_001237 COc1cc(Br)c(/C=N/NC(=O)c2ccccc2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I13 compound treatment 17560.0 -121000.0 -3.23 18800.0 -149000.0 -4.03 -5.1361 -0.9939 3552087 CHDI2_001238 Oc1cccc(/C=N/NC(=O)c2ccccc2O)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I14 compound treatment 125880.0 -12400.0 -0.33 119320.0 -48500.0 -1.31 -1.163 -0.8591 3552418 CHDI2_001239 Oc1ccccc1C(=O)N/N=C/c2cc3ccccc3n2S(=O)(=O)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I15 compound treatment 10720.0 -128000.0 -3.41 10400.0 -157000.0 -4.26 -5.4263 -0.9939 3552091 CHDI2_001240 Oc1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I16 compound treatment 88840.0 -49500.0 -1.32 105560.0 -62200.0 -1.68 -2.127 -0.9929 3552345 CHDI2_001241 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I17 compound treatment 116160.0 -22200.0 -0.59 128880.0 -38900.0 -1.05 -1.1639 -0.963 3552095 CHDI2_001242 Oc1ccc(O)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I18 compound treatment 128800.0 -9510.0 -0.25 138000.0 -29800.0 -0.81 -0.7502 -0.8871 3552349 CHDI2_001243 Oc1ccccc1C(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I19 compound treatment 109040.0 -29300.0 -0.78 127480.0 -40300.0 -1.09 -1.3254 -0.9867 3552098 CHDI2_001244 Oc1ccc(/C=N/NC(=O)c2ccccc2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I20 compound treatment 120840.0 -17500.0 -0.47 120840.0 -47000.0 -1.27 -1.2293 -0.9077 3552420 CHDI2_001245 OB(O)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I21 compound treatment 134800.0 -3510.0 -0.09 118000.0 -49800.0 -1.35 -1.0196 -0.7545 3554228 CHDI2_001246 O=C(NN=C1CCCCCC1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I22 compound treatment 120720.0 -17600.0 -0.47 121400.0 -46400.0 -1.26 -1.2208 -0.9102 3552894 CHDI2_001247 [O-][n+]1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I23 mock treatment 128880.0 -9430.0 -0.25 168920.0 1130.0 0.03 -0.1568 -0.6171 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 I24 mock treatment 137040.0 -1270.0 -0.03 162280.0 -5510.0 -0.15 -0.1296 -0.8465 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J01 compound treatment 173800.0 35500.0 0.95 141280.0 -26500.0 -0.72 0.1637 0.1376 3552565 CHDI2_001248 COc1cc(Cl)c(/C=N/NC(=O)c2ccccn2)c(Cl)c1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J02 compound treatment 40080.0 -98200.0 -2.63 50200.0 -118000.0 -3.18 -4.1091 -0.9955 3213410 CHDI2_001249 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J03 compound treatment 34600.0 -104000.0 -2.77 26680.0 -141000.0 -3.82 -4.663 -0.9876 3552569 CHDI2_001250 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J04 mock treatment 168080.0 29800.0 0.8 133640.0 -34200.0 -0.92 -0.0907 -0.0744 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J05 compound treatment 131200.0 -7110.0 -0.19 126240.0 -41600.0 -1.12 -0.93 -0.8151 3552951 CHDI2_001251 O=C(N/N=C/C1=CCCCC1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J06 compound treatment 130120.0 -8190.0 -0.22 125000.0 -42800.0 -1.16 -0.9741 -0.8262 3213412 CHDI2_001252 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J07 compound treatment 112280.0 -26000.0 -0.7 110640.0 -57200.0 -1.55 -1.5864 -0.935 3552573 CHDI2_001253 Oc1c(/C=N/NC(=O)c2ccccn2)cc(Br)cc1[N+](=O)[O-] 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J08 mock treatment 124960.0 -13400.0 -0.36 120760.0 -47000.0 -1.27 -1.1529 -0.8718 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J09 compound treatment 10680.0 -128000.0 -3.41 10600.0 -157000.0 -4.26 -5.4232 -0.994 3552578 CHDI2_001254 CCN(CC)c1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J10 compound treatment 62640.0 -75700.0 -2.02 67160.0 -101000.0 -2.72 -3.3577 -0.9893 3214566 CHDI2_001255 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J11 compound treatment 115280.0 -23000.0 -0.62 127520.0 -40300.0 -1.09 -1.2066 -0.9635 3552582 CHDI2_001256 O=C(N/N=C/c1ccc2OCCc2c1)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J12 compound treatment 123560.0 -14800.0 -0.39 121320.0 -46500.0 -1.26 -1.1686 -0.8863 3214568 CHDI2_001257 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J13 compound treatment 34880.0 -103000.0 -2.77 35880.0 -132000.0 -3.57 -4.4815 -0.992 3552586 CHDI2_001258 Oc1cccc(/C=N/NC(=O)c2ccccn2)c1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J14 compound treatment 115160.0 -23200.0 -0.62 126960.0 -40800.0 -1.11 -1.2196 -0.9625 3214215 CHDI2_001259 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J15 compound treatment 15160.0 -123000.0 -3.29 14720.0 -153000.0 -4.14 -5.2596 -0.9935 3552590 CHDI2_001260 Oc1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J16 compound treatment 106440.0 -31900.0 -0.85 121560.0 -46200.0 -1.25 -1.4879 -0.9825 3215176 CHDI2_001261 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J17 compound treatment 135200.0 -3110.0 -0.08 139920.0 -27900.0 -0.75 -0.5924 -0.7804 3552594 CHDI2_001262 Oc1ccc(O)c(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J18 compound treatment 110920.0 -27400.0 -0.73 119640.0 -48200.0 -1.3 -1.4399 -0.9629 3214824 CHDI2_001263 NNC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J19 compound treatment 103920.0 -34400.0 -0.92 104840.0 -63000.0 -1.7 -1.8556 -0.9581 1936679 CHDI2_001264 Oc1ccc(/C=N/NC(=O)c2ccccn2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J20 compound treatment 139440.0 1130.0 0.03 128520.0 -39300.0 -1.06 -0.7305 -0.6867 3553235 CHDI2_001265 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J21 compound treatment 125840.0 -12500.0 -0.33 131280.0 -36500.0 -0.99 -0.9349 -0.8961 3552955 CHDI2_001266 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J22 compound treatment 124320.0 -14000.0 -0.37 128200.0 -39600.0 -1.07 -1.0226 -0.9007 3553843 CHDI2_001267 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J23 mock treatment 130880.0 -7430.0 -0.2 150960.0 -16800.0 -0.46 -0.4628 -0.9308 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 J24 mock treatment 131200.0 -7110.0 -0.19 169160.0 1370.0 0.04 -0.1083 -0.559 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K01 compound treatment 182480.0 44200.0 1.18 171400.0 3610.0 0.1 0.9045 0.7629 3552103 CHDI2_001268 COc1cccc(OC)c1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K02 compound treatment 153240.0 14900.0 0.4 133680.0 -34100.0 -0.92 -0.3707 -0.3684 3552353 CHDI2_001269 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K03 compound treatment 134520.0 -3790.0 -0.1 144400.0 -23400.0 -0.63 -0.5195 -0.81 1913656 CHDI2_001270 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K04 compound treatment 120720.0 -17600.0 -0.47 132560.0 -35200.0 -0.95 -1.0072 -0.947 3552357 CHDI2_001271 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K05 compound treatment 105720.0 -32600.0 -0.87 120640.0 -47200.0 -1.28 -1.5191 -0.9827 3552108 CHDI2_001272 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K06 compound treatment 117000.0 -21300.0 -0.57 123600.0 -44200.0 -1.2 -1.2491 -0.9425 3552361 CHDI2_001273 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K07 compound treatment 109120.0 -29200.0 -0.78 118400.0 -49400.0 -1.34 -1.4977 -0.9672 3552977 CHDI2_001274 O=C(N/N=C/Cc1ccccc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K08 compound treatment 104560.0 -33800.0 -0.9 131080.0 -36700.0 -0.99 -1.3412 -0.9988 3552898 CHDI2_001275 O=C(N/N=C/c1ccc2ccccc2n1)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K09 compound treatment 130360.0 -7950.0 -0.21 128640.0 -39200.0 -1.06 -0.8999 -0.8324 3552111 CHDI2_001276 CC1(C)COC(CCC/C=N/NC(=O)c2ccccc2O)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K10 compound treatment 118200.0 -20100.0 -0.54 128560.0 -39200.0 -1.06 -1.1314 -0.9503 3552365 CHDI2_001277 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K11 compound treatment 118040.0 -20300.0 -0.54 123760.0 -44000.0 -1.19 -1.2263 -0.9364 3552115 CHDI2_001278 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3ccccc3O)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K12 compound treatment 126640.0 -11700.0 -0.31 148880.0 -18900.0 -0.51 -0.5828 -0.9718 3552366 CHDI2_001279 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K13 compound treatment 84760.0 -53600.0 -1.43 92800.0 -75000.0 -2.03 -2.4485 -0.9854 3552118 CHDI2_001280 Oc1ccccc1C(=O)N/N=C/c2cc(Br)cs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K14 compound treatment 123880.0 -14400.0 -0.39 132760.0 -35000.0 -0.95 -0.9436 -0.9215 3552369 CHDI2_001281 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K15 compound treatment 113600.0 -24700.0 -0.66 125640.0 -42200.0 -1.14 -1.2743 -0.9663 3552981 CHDI2_001282 COC(=O)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K16 compound treatment 101000.0 -37300.0 -1.0 114800.0 -53000.0 -1.43 -1.7202 -0.9843 3552902 CHDI2_001283 Cc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K17 compound treatment 117160.0 -21200.0 -0.57 120320.0 -47500.0 -1.29 -1.3088 -0.9321 3552121 CHDI2_001284 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K18 compound treatment 88040.0 -50300.0 -1.34 95160.0 -72600.0 -1.97 -2.3413 -0.9828 3552373 CHDI2_001285 Oc1ccccc1C(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K19 compound treatment 122960.0 -15400.0 -0.41 128440.0 -39400.0 -1.07 -1.0437 -0.9141 3552125 CHDI2_001286 Oc1ccccc1C(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K20 compound treatment 119640.0 -18700.0 -0.5 116760.0 -51000.0 -1.38 -1.3301 -0.9054 3552377 CHDI2_001287 Oc1ccccc1C(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K21 compound treatment 119360.0 -19000.0 -0.51 135080.0 -32700.0 -0.89 -0.9847 -0.965 1922658 CHDI2_001288 Oc1ccccc1C(=O)N/N=C/c2ccc(F)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K22 compound treatment 137440.0 -871.0 -0.02 137040.0 -30800.0 -0.83 -0.6052 -0.7266 3552381 CHDI2_001289 Oc1ccccc1C(=O)N/N=C/c2ccc3ccccc3n2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K23 mock treatment 133720.0 -4590.0 -0.12 147920.0 -19900.0 -0.54 -0.4673 -0.8467 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 K24 mock treatment 129480.0 -8830.0 -0.24 167880.0 87.1 0.0 -0.1654 -0.7 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L01 compound treatment 163920.0 25600.0 0.69 141280.0 -26500.0 -0.72 -0.0232 -0.0233 3552603 CHDI2_001290 COc1cccc(OC)c1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L02 compound treatment 51920.0 -86400.0 -2.31 40760.0 -127000.0 -3.44 -4.0658 -0.9813 3214346 CHDI2_001291 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L03 compound treatment 134520.0 -3790.0 -0.1 134160.0 -33600.0 -0.91 -0.7155 -0.781 3552607 CHDI2_001292 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L04 compound treatment 113680.0 -24600.0 -0.66 142560.0 -25200.0 -0.68 -0.9489 -0.9998 3214446 CHDI2_001293 CCCCCCC/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L05 compound treatment 129680.0 -8630.0 -0.23 131160.0 -36600.0 -0.99 -0.8645 -0.849 3552611 CHDI2_001294 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L06 compound treatment 14760.0 -124000.0 -3.3 18720.0 -149000.0 -4.04 -5.1906 -0.9951 3214578 CHDI2_001295 COc1cc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L07 compound treatment 118240.0 -20100.0 -0.54 120600.0 -47200.0 -1.28 -1.283 -0.9258 3552957 CHDI2_001296 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L08 compound treatment 102920.0 -35400.0 -0.95 114320.0 -53500.0 -1.45 -1.693 -0.9788 3214706 CHDI2_001297 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L09 compound treatment 104080.0 -34200.0 -0.92 132160.0 -35600.0 -0.96 -1.3296 -0.9997 3552614 CHDI2_001298 CC1(C)COC(CCC/C=N/NC(=O)c2ccccn2)OC1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L10 compound treatment 104200.0 -34100.0 -0.91 121240.0 -46600.0 -1.26 -1.5364 -0.9874 3214810 CHDI2_001299 C/C(=N\NC(=O)CCCCCC(=O)NO)/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L11 compound treatment 126920.0 -11400.0 -0.3 128120.0 -39700.0 -1.07 -0.9749 -0.8732 3552618 CHDI2_001300 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3ccccn3)o2)n1C 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L12 compound treatment 117440.0 -20900.0 -0.56 116480.0 -51300.0 -1.39 -1.3771 -0.9198 3553399 CHDI2_001301 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3cccc(c3)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L13 compound treatment 107280.0 -31000.0 -0.83 113640.0 -54200.0 -1.47 -1.6236 -0.9637 3552622 CHDI2_001302 Brc1csc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L14 compound treatment 114840.0 -23500.0 -0.63 116520.0 -51300.0 -1.39 -1.4255 -0.9357 3553462 CHDI2_001303 CCCCCCC/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L15 compound treatment 115640.0 -22700.0 -0.61 146840.0 -21000.0 -0.57 -0.8299 -0.9994 3552961 CHDI2_001304 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccn2)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L16 compound treatment 109840.0 -28500.0 -0.76 130440.0 -37400.0 -1.01 -1.2536 -0.9902 3553506 CHDI2_001305 COc1cc(Br)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L17 compound treatment 124320.0 -14000.0 -0.37 134280.0 -33500.0 -0.91 -0.9062 -0.9233 3552626 CHDI2_001306 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L18 compound treatment 112520.0 -25800.0 -0.69 120320.0 -47500.0 -1.29 -1.3966 -0.9575 3553553 CHDI2_001307 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L19 compound treatment 114760.0 -23600.0 -0.63 122840.0 -45000.0 -1.22 -1.306 -0.953 3552630 CHDI2_001308 O=C(N/N=C/c1ccc-2c(Cc3ccccc32)c1)c4ccccn4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L20 compound treatment 117000.0 -21300.0 -0.57 124320.0 -43500.0 -1.18 -1.2353 -0.9446 3554247 CHDI2_001309 C/C(=N\NC(=O)c1cccc(c1)C(=O)NO)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L21 compound treatment 111440.0 -26900.0 -0.72 124680.0 -43100.0 -1.17 -1.3336 -0.9729 3552634 CHDI2_001310 Fc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L22 compound treatment 117680.0 -20600.0 -0.55 125480.0 -42300.0 -1.15 -1.2002 -0.9439 3552755 CHDI2_001311 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L23 mock treatment 129120.0 -9190.0 -0.25 163240.0 -4550.0 -0.12 -0.261 -0.949 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 L24 mock treatment 124880.0 -13400.0 -0.36 180280.0 12500.0 0.34 -0.015 -0.0304 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M01 compound treatment 167120.0 28800.0 0.77 181400.0 13600.0 0.37 0.8054 0.9429 3552129 CHDI2_001312 Oc1ccc(/C=N/NC(=O)c2ccccc2O)cc1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M02 compound treatment 152600.0 14300.0 0.38 124320.0 -43500.0 -1.18 -0.5619 -0.4541 3552383 CHDI2_001313 Cc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M03 compound treatment 107480.0 -30800.0 -0.82 43040.0 -125000.0 -3.38 -2.9713 -0.8547 3552133 CHDI2_001314 Oc1ccccc1C(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M04 compound treatment 120480.0 -17800.0 -0.48 128920.0 -38900.0 -1.05 -1.0814 -0.9359 3552385 CHDI2_001315 COc1cc(/C=N/NC(=O)c2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M05 compound treatment 18240.0 -120000.0 -3.21 13160.0 -155000.0 -4.19 -5.2312 -0.9914 3552138 CHDI2_001316 Oc1ccc(F)cc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M06 compound treatment 137920.0 -391.0 -0.01 153520.0 -14300.0 -0.39 -0.2806 -0.726 3552386 CHDI2_001317 O[C@@H](/C=N/NC(=O)c1ccccc1O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M07 compound treatment 10800.0 -128000.0 -3.41 12400.0 -155000.0 -4.21 -5.3865 -0.9946 3552142 CHDI2_001318 Oc1ccccc1C(=O)N/N=C/c2coc3ccccc3c2=O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M08 compound treatment 125800.0 -12500.0 -0.33 141480.0 -26300.0 -0.71 -0.7403 -0.9407 3552388 CHDI2_001319 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M09 compound treatment 121120.0 -17200.0 -0.46 130040.0 -37800.0 -1.02 -1.0479 -0.935 3552985 CHDI2_001320 O=C(N/N=C/c1cc2ccccc2n1S(=O)(=O)c3ccccc3)c4ccccn4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M10 compound treatment 112920.0 -25400.0 -0.68 138080.0 -29700.0 -0.8 -1.0491 -0.9965 3552910 CHDI2_001321 O[C@@H](/C=N/NC(=O)c1ccccn1)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M11 compound treatment 109720.0 -28600.0 -0.76 125880.0 -41900.0 -1.13 -1.3431 -0.9816 3552146 CHDI2_001322 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M12 compound treatment 120000.0 -18300.0 -0.49 118160.0 -49600.0 -1.34 -1.2965 -0.9065 1919426 CHDI2_001323 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M13 compound treatment 121080.0 -17200.0 -0.46 126000.0 -41800.0 -1.13 -1.126 -0.9216 3552862 CHDI2_001324 O=C(N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3)c4ccccn4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M14 compound treatment 125880.0 -12400.0 -0.33 145240.0 -22600.0 -0.61 -0.6669 -0.9592 3552913 CHDI2_001325 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M15 compound treatment 114920.0 -23400.0 -0.63 148960.0 -18800.0 -0.51 -0.8029 -0.9948 3552150 CHDI2_001326 OB(O)c1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M16 compound treatment 122520.0 -15800.0 -0.42 139800.0 -28000.0 -0.76 -0.8345 -0.9619 3552389 CHDI2_001327 CCOc1cccc(/C=N/NC(=O)c2ccccc2O)c1OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M17 compound treatment 133240.0 -5070.0 -0.14 133840.0 -34000.0 -0.92 -0.7459 -0.8028 1913661 CHDI2_001328 Oc1ccccc1C(=O)N/N=C/c2ccco2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M18 compound treatment 112360.0 -26000.0 -0.69 127120.0 -40700.0 -1.1 -1.2695 -0.9753 3552391 CHDI2_001329 Oc1ccccc1C(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M19 compound treatment 129360.0 -8950.0 -0.24 143040.0 -24800.0 -0.67 -0.6432 -0.9038 3552154 CHDI2_001330 Oc1ccccc1C(=O)N/N=C/c2ccoc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M20 compound treatment 110800.0 -27500.0 -0.74 125200.0 -42600.0 -1.15 -1.3357 -0.9765 1912672 CHDI2_001331 CN(C)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M21 compound treatment 123040.0 -15300.0 -0.41 112920.0 -54900.0 -1.49 -1.3393 -0.8693 3552158 CHDI2_001332 Oc1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M22 compound treatment 62960.0 -75400.0 -2.02 73960.0 -93800.0 -2.54 -3.2215 -0.9934 1919995 CHDI2_001333 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4ccccc4O)ccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M23 mock treatment 143520.0 5210.0 0.14 156480.0 -11300.0 -0.31 -0.118 -0.3508 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 M24 mock treatment 136160.0 -2150.0 -0.06 160280.0 -7510.0 -0.2 -0.1845 -0.8729 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N01 compound treatment 125560.0 -12800.0 -0.34 115200.0 -52600.0 -1.42 -1.248 -0.8524 3552638 CHDI2_001334 Oc1ccc(/C=N/NC(=O)c2ccccn2)cc1F 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N02 compound treatment 48520.0 -89800.0 -2.4 50840.0 -117000.0 -3.17 -3.9372 -0.9907 3213540 CHDI2_001335 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N03 compound treatment 124000.0 -14300.0 -0.38 127960.0 -39800.0 -1.08 -1.0332 -0.9029 3552642 CHDI2_001336 Fc1ccc(/C=N/NC(=O)c2ccccn2)cc1Oc3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N04 compound treatment 8840.0 -129000.0 -3.46 9880.0 -158000.0 -4.28 -5.4718 -0.9945 3213580 CHDI2_001337 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(c(F)c1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N05 compound treatment 93880.0 -44400.0 -1.19 95080.0 -72700.0 -1.97 -2.2323 -0.9708 3552646 CHDI2_001338 Oc1ccc(F)cc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N06 compound treatment 123800.0 -14500.0 -0.39 123240.0 -44600.0 -1.21 -1.1273 -0.8897 3213542 CHDI2_001339 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N07 compound treatment 122840.0 -15500.0 -0.41 119080.0 -48700.0 -1.32 -1.2251 -0.8864 3552650 CHDI2_001340 O=C(N/N=C/c1coc2ccccc2c1=O)c3ccccn3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N08 compound treatment 112880.0 -25400.0 -0.68 147440.0 -20400.0 -0.55 -0.8706 -0.9945 3213578 CHDI2_001341 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N09 compound treatment 113280.0 -25000.0 -0.67 134680.0 -33100.0 -0.9 -1.1073 -0.9897 3552965 CHDI2_001342 CN(C)CCCOc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N10 compound treatment 82280.0 -56000.0 -1.5 99600.0 -68200.0 -1.85 -2.3652 -0.9947 3214696 CHDI2_001343 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N11 compound treatment 119120.0 -19200.0 -0.51 120760.0 -47000.0 -1.27 -1.2633 -0.9202 3552654 CHDI2_001344 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N12 compound treatment 105560.0 -32800.0 -0.88 123080.0 -44700.0 -1.21 -1.4754 -0.9874 3214698 CHDI2_001345 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N13 compound treatment 113520.0 -24800.0 -0.66 121880.0 -45900.0 -1.24 -1.3478 -0.9567 3552969 CHDI2_001346 CCOc1cc(/C=N/NC(=O)c2ccccn2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N14 compound treatment 9680.0 -129000.0 -3.44 12960.0 -155000.0 -4.19 -5.3969 -0.9952 3214734 CHDI2_001347 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N15 compound treatment 92840.0 -45500.0 -1.22 109400.0 -58400.0 -1.58 -1.9779 -0.9916 3552658 CHDI2_001348 OB(O)c1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N16 compound treatment 103800.0 -34500.0 -0.92 136560.0 -31200.0 -0.85 -1.2506 -0.999 3215306 CHDI2_001349 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N17 compound treatment 108560.0 -29800.0 -0.8 136400.0 -31400.0 -0.85 -1.1637 -0.9995 1937927 CHDI2_001350 O=C(N/N=C/c1ccco1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N18 compound treatment 8080.0 -130000.0 -3.48 11880.0 -156000.0 -4.22 -5.4479 -0.9955 3215346 CHDI2_001351 ONC(=O)CCCCC(=O)N/N=C/c1ccc(c(F)c1)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N19 compound treatment 114440.0 -23900.0 -0.64 116840.0 -51000.0 -1.38 -1.4269 -0.9387 3552663 CHDI2_001352 O=C(N/N=C/c1ccoc1)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N20 compound treatment 123000.0 -15300.0 -0.41 136320.0 -31500.0 -0.85 -0.8921 -0.9436 3553309 CHDI2_001353 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N21 compound treatment 93240.0 -45100.0 -1.21 95800.0 -72000.0 -1.95 -2.2307 -0.9733 3552665 CHDI2_001354 Oc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N22 compound treatment 116760.0 -21600.0 -0.58 139240.0 -28600.0 -0.77 -0.9542 -0.9896 3553913 CHDI2_001355 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N23 mock treatment 128520.0 -9790.0 -0.26 170080.0 2290.0 0.06 -0.1414 -0.5255 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 N24 mock treatment 149680.0 11400.0 0.3 167240.0 -553.0 -0.01 0.2045 0.6715 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O01 compound treatment 173440.0 35100.0 0.94 178920.0 11100.0 0.3 0.8774 0.8892 3552163 CHDI2_001356 OCCOc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O02 compound treatment 188960.0 50600.0 1.35 134200.0 -33600.0 -0.91 0.3149 0.193 3552395 CHDI2_001357 Oc1ccccc1C(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O03 compound treatment 122440.0 -15900.0 -0.42 139720.0 -28100.0 -0.76 -0.8376 -0.9622 3552167 CHDI2_001358 OCCOc1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O04 compound treatment 139160.0 849.0 0.02 129520.0 -38300.0 -1.04 -0.7166 -0.6914 3552397 CHDI2_001359 Cn1cc(/C=N/NC(=O)c2ccccc2O)c3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O05 compound treatment 110520.0 -27800.0 -0.74 136160.0 -31600.0 -0.86 -1.1312 -0.9975 3552171 CHDI2_001360 OCCOc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O06 compound treatment 49120.0 -89200.0 -2.39 85880.0 -81900.0 -2.22 -3.2551 -0.9993 3552399 CHDI2_001361 Oc1ccccc1C(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O07 compound treatment 7640.0 -131000.0 -3.5 8880.0 -159000.0 -4.3 -5.5136 -0.9947 3552175 CHDI2_001362 COc1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O08 compound treatment 97440.0 -40900.0 -1.09 122920.0 -44900.0 -1.21 -1.6321 -0.9986 3552401 CHDI2_001363 Oc1ccccc1C(=O)N/N=C/C2=CCCCC2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O09 compound treatment 11160.0 -127000.0 -3.4 10680.0 -157000.0 -4.25 -5.4126 -0.9939 3552179 CHDI2_001364 COc1ccc(O)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O10 compound treatment 111800.0 -26500.0 -0.71 120320.0 -47500.0 -1.29 -1.4102 -0.9607 3552403 CHDI2_001365 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1ccccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O11 compound treatment 96040.0 -42300.0 -1.13 117840.0 -50000.0 -1.35 -1.7558 -0.996 3552866 CHDI2_001366 O=C(N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3)c4ccccn4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O12 compound treatment 86280.0 -52000.0 -1.39 106440.0 -61400.0 -1.66 -2.1586 -0.9961 3552915 CHDI2_001367 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O13 compound treatment 93160.0 -45200.0 -1.21 106280.0 -61500.0 -1.67 -2.0315 -0.9876 3552184 CHDI2_001368 COc1cc(/C=C/C=N/NC(=O)c2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O14 compound treatment 104000.0 -34300.0 -0.92 125960.0 -41800.0 -1.13 -1.4498 -0.9946 3552404 CHDI2_001369 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O15 compound treatment 41080.0 -97200.0 -2.6 23960.0 -144000.0 -3.89 -4.5925 -0.9807 3552188 CHDI2_001370 Cc1ccc(O)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O16 compound treatment 106920.0 -31400.0 -0.84 130560.0 -37200.0 -1.01 -1.3065 -0.9959 3552406 CHDI2_001371 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O17 compound treatment 141920.0 3610.0 0.1 131920.0 -35900.0 -0.97 -0.6185 -0.6337 3552191 CHDI2_001372 OCc1ccc(/C=N/NC(=O)c2ccccc2O)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O18 compound treatment 103240.0 -35100.0 -0.94 161680.0 -6110.0 -0.17 -0.7804 -0.8192 3554239 CHDI2_001373 C/C(=N\NC(=O)c1ccccc1O)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O19 compound treatment 8400.0 -130000.0 -3.47 10440.0 -157000.0 -4.26 -5.4694 -0.9949 3552195 CHDI2_001374 Oc1ccccc1C(=O)N/N=C/c2ccc3ccccc3c2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O20 compound treatment 132200.0 -6110.0 -0.16 145760.0 -22000.0 -0.6 -0.5374 -0.8688 3552408 CHDI2_001375 CN(C)CCCOc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O21 compound treatment 11000.0 -127000.0 -3.41 35600.0 -132000.0 -3.58 -4.9386 -0.9997 3552199 CHDI2_001376 Oc1ccccc1C(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O22 compound treatment 110960.0 -27400.0 -0.73 143240.0 -24600.0 -0.66 -0.9873 -0.9989 3552410 CHDI2_001377 CCOc1cc(/C=N/NC(=O)c2ccccc2O)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O23 mock treatment 112480.0 -25800.0 -0.69 159040.0 -8750.0 -0.24 -0.6561 -0.8983 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 O24 mock treatment 136480.0 -1830.0 -0.05 187320.0 19500.0 0.53 0.3392 0.6389 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P01 compound treatment 180040.0 41700.0 1.12 147240.0 -20600.0 -0.56 0.3958 0.3174 3552673 CHDI2_001378 OCCOc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P02 compound treatment 150720.0 12400.0 0.33 120680.0 -47100.0 -1.28 -0.6672 -0.5062 3213622 CHDI2_001379 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)c(O)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P03 compound treatment 93200.0 -45100.0 -1.21 101040.0 -66800.0 -1.81 -2.1311 -0.9807 3552677 CHDI2_001380 OCCOc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P04 compound treatment 28760.0 -110000.0 -2.93 44480.0 -123000.0 -3.34 -4.4327 -0.9979 3213666 CHDI2_001381 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P05 compound treatment 97320.0 -41000.0 -1.1 120920.0 -46900.0 -1.27 -1.6726 -0.9974 3552680 CHDI2_001382 OCCOc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P06 compound treatment 108720.0 -29600.0 -0.79 125280.0 -42500.0 -1.15 -1.3735 -0.9833 3213624 CHDI2_001383 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P07 compound treatment 41360.0 -97000.0 -2.59 40760.0 -127000.0 -3.44 -4.2656 -0.9903 3552684 CHDI2_001384 COc1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P08 compound treatment 100000.0 -38300.0 -1.02 125200.0 -42600.0 -1.15 -1.54 -0.9983 3213664 CHDI2_001385 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P09 compound treatment 80480.0 -57800.0 -1.55 97880.0 -69900.0 -1.89 -2.4322 -0.995 3552688 CHDI2_001386 COc1ccc(O)c(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P10 compound treatment 97560.0 -40800.0 -1.09 117480.0 -50300.0 -1.36 -1.7339 -0.9939 3214778 CHDI2_001387 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)c(O)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P11 compound treatment 81640.0 -56700.0 -1.52 96200.0 -71600.0 -1.94 -2.4424 -0.9926 3552973 CHDI2_001388 CN(CCO)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P12 compound treatment 110200.0 -28100.0 -0.75 111560.0 -56200.0 -1.52 -1.6082 -0.9471 3214780 CHDI2_001389 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P13 compound treatment 111440.0 -26900.0 -0.72 138440.0 -29400.0 -0.79 -1.0702 -0.9987 3552692 CHDI2_001390 COc1cc(/C=C/C=N/NC(=O)c2ccccn2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P14 compound treatment 95880.0 -42400.0 -1.13 123400.0 -44400.0 -1.2 -1.6524 -0.9996 3214820 CHDI2_001391 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P15 compound treatment 78640.0 -59700.0 -1.6 87760.0 -80000.0 -2.17 -2.6607 -0.9887 3552696 CHDI2_001392 Cc1ccc(O)c(/C=N/NC(=O)c2ccccn2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P16 compound treatment 102840.0 -35500.0 -0.95 117600.0 -50200.0 -1.36 -1.6318 -0.9846 3215388 CHDI2_001393 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)c(O)c(Br)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P17 compound treatment 107760.0 -30600.0 -0.82 133280.0 -34500.0 -0.93 -1.2385 -0.9978 3552700 CHDI2_001394 OCc1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P18 compound treatment 102960.0 -35400.0 -0.95 124000.0 -43800.0 -1.19 -1.507 -0.9937 3215432 CHDI2_001395 CN(CCO)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P19 compound treatment 87680.0 -50600.0 -1.35 91280.0 -76500.0 -2.07 -2.4223 -0.9788 3552703 CHDI2_001396 Oc1c(/C=N/NC(=O)c2ccccn2)ccc3ccccc13 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P20 compound treatment 105360.0 -33000.0 -0.88 123560.0 -44200.0 -1.2 -1.47 -0.9886 3553350 CHDI2_001397 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P21 compound treatment 72840.0 -65500.0 -1.75 101840.0 -66000.0 -1.79 -2.5009 -1.0 3552707 CHDI2_001398 Clc1cccc(c1)c2ccc(/C=N/NC(=O)c3ccccn3)o2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P22 compound treatment 116640.0 -21700.0 -0.58 145640.0 -22200.0 -0.6 -0.834 -0.9999 3553954 CHDI2_001399 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P23 mock treatment 126160.0 -12200.0 -0.33 158520.0 -9270.0 -0.25 -0.4073 -0.9919 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2406 P24 mock treatment 138880.0 569.0 0.02 159680.0 -8110.0 -0.22 -0.1445 -0.6565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A01 compound treatment 175920.0 38100.0 1.02 194480.0 56100.0 1.52 1.7929 0.9811 3553992 CHDI2_001400 Cc1[nH]cnc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A02 compound treatment 47240.0 -90600.0 -2.42 43280.0 -95100.0 -2.58 -3.5354 -0.9995 3634596 CHDI2_001401 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A03 compound treatment 9160.0 -129000.0 -3.44 9560.0 -129000.0 -3.49 -4.9011 -1.0 3551957 CHDI2_001402 Oc1ccccc1C(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A04 compound treatment 7600.0 -130000.0 -3.48 7800.0 -131000.0 -3.54 -4.9643 -1.0 3634598 CHDI2_001403 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A05 compound treatment 164240.0 26400.0 0.71 182360.0 43900.0 1.19 1.34 0.9689 3552237 CHDI2_001404 Cc1[nH]cnc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A06 compound treatment 171280.0 33400.0 0.89 191000.0 52600.0 1.42 1.6386 0.9749 3634600 CHDI2_001405 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OC/C=C/COc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A07 compound treatment 163480.0 25600.0 0.69 115760.0 -22700.0 -0.61 0.0507 0.0551 3552453 CHDI2_001406 Br/C(=C\c1ccccc1)/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A08 compound treatment 7480.0 -130000.0 -3.49 5840.0 -133000.0 -3.59 -5.0041 -0.9999 3634602 CHDI2_001407 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A09 compound treatment 22680.0 -115000.0 -3.08 11840.0 -127000.0 -3.43 -4.6018 -0.9986 3634604 CHDI2_001408 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN3CCCCCCC3)CC(O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A10 compound treatment 170120.0 32300.0 0.86 191960.0 53500.0 1.45 1.635 0.9693 3634605 CHDI2_001409 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A11 compound treatment 164800.0 26900.0 0.72 184800.0 46400.0 1.26 1.3973 0.9652 3562114 CHDI2_001410 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A12 compound treatment 7480.0 -130000.0 -3.49 8560.0 -130000.0 -3.52 -4.9521 -1.0 3634607 CHDI2_001411 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A13 compound treatment 103200.0 -34700.0 -0.93 117960.0 -20500.0 -0.55 -1.0473 -0.9697 3561878 CHDI2_001412 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A14 compound treatment 8000.0 -130000.0 -3.47 8640.0 -130000.0 -3.51 -4.9407 -1.0 3634609 CHDI2_001413 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A15 compound treatment 177200.0 39300.0 1.05 189880.0 51500.0 1.39 1.7291 0.9904 3614528 CHDI2_001414 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A16 compound treatment 9600.0 -128000.0 -3.43 8880.0 -130000.0 -3.51 -4.9058 -0.9999 3634611 CHDI2_001415 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A17 compound treatment 182600.0 44700.0 1.2 203680.0 65300.0 1.77 2.0954 0.982 3614462 CHDI2_001416 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A18 compound treatment 13720.0 -124000.0 -3.32 9160.0 -129000.0 -3.5 -4.8226 -0.9997 3634613 CHDI2_001417 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A19 compound treatment 157480.0 19600.0 0.52 162680.0 24300.0 0.66 0.8354 0.9938 3614540 CHDI2_001418 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A20 compound treatment 9080.0 -129000.0 -3.44 9720.0 -129000.0 -3.48 -4.8996 -1.0 3634615 CHDI2_001419 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A21 compound treatment 7800.0 -130000.0 -3.48 8960.0 -129000.0 -3.5 -4.9384 -1.0 3614392 CHDI2_001420 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A22 compound treatment 183440.0 45600.0 1.22 201000.0 62600.0 1.69 2.06 0.987 3634617 CHDI2_001421 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A23 mock treatment 196600.0 58700.0 1.57 207440.0 69000.0 1.87 2.4322 0.9963 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 A24 mock treatment 176080.0 38200.0 1.02 202520.0 64100.0 1.74 1.9499 0.9681 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B01 compound treatment 150360.0 12500.0 0.33 181360.0 42900.0 1.16 1.0583 0.875 3634619 CHDI2_001422 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B02 compound treatment 136800.0 -1070.0 -0.03 158360.0 19900.0 0.54 0.3616 0.6688 3634621 CHDI2_001423 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B03 compound treatment 150080.0 12200.0 0.33 193800.0 55400.0 1.5 1.2912 0.8414 3634623 CHDI2_001424 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B04 compound treatment 162160.0 24300.0 0.65 165360.0 26900.0 0.73 0.9752 0.9983 3634625 CHDI2_001425 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B05 compound treatment 138400.0 534.0 0.01 160880.0 22500.0 0.61 0.4401 0.7235 3634627 CHDI2_001426 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B06 compound treatment 167080.0 29200.0 0.78 155360.0 16900.0 0.46 0.8769 0.9677 3634629 CHDI2_001427 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OC/C=C/COc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B07 compound treatment 9520.0 -128000.0 -3.43 7760.0 -131000.0 -3.54 -4.9288 -0.9999 3634631 CHDI2_001428 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B08 compound treatment 129880.0 -7990.0 -0.21 133240.0 -5180.0 -0.14 -0.2502 -0.9792 3634633 CHDI2_001429 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B09 compound treatment 135720.0 -2150.0 -0.06 150080.0 11700.0 0.32 0.1826 0.5692 3634635 CHDI2_001430 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B10 compound treatment 136000.0 -1870.0 -0.05 174600.0 36200.0 0.98 0.6573 0.6702 3634637 CHDI2_001431 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B11 compound treatment 9160.0 -129000.0 -3.44 8880.0 -130000.0 -3.51 -4.9142 -1.0 3634639 CHDI2_001432 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B12 compound treatment 138120.0 254.0 0.01 149480.0 11100.0 0.3 0.2165 0.723 3634641 CHDI2_001433 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B13 compound treatment 134920.0 -2950.0 -0.08 169520.0 31100.0 0.84 0.5396 0.6381 3634643 CHDI2_001434 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B14 compound treatment 136840.0 -1030.0 -0.03 165880.0 27500.0 0.74 0.5063 0.6805 3634645 CHDI2_001435 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B15 compound treatment 13120.0 -125000.0 -3.34 11600.0 -127000.0 -3.43 -4.7872 -0.9999 3634647 CHDI2_001436 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B16 compound treatment 133640.0 -4230.0 -0.11 170560.0 32100.0 0.87 0.5353 0.6101 3634649 CHDI2_001437 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B17 compound treatment 144800.0 6930.0 0.19 188200.0 49800.0 1.35 1.0841 0.7969 3634651 CHDI2_001438 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B18 compound treatment 157040.0 19200.0 0.51 196320.0 57900.0 1.57 1.4711 0.8919 3634653 CHDI2_001439 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B19 compound treatment 156040.0 18200.0 0.49 185280.0 46900.0 1.27 1.2408 0.9133 3634655 CHDI2_001440 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B20 compound treatment 145840.0 7970.0 0.21 221480.0 83100.0 2.25 1.7409 0.7707 3634657 CHDI2_001441 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B21 compound treatment 148160.0 10300.0 0.28 212120.0 73700.0 2.0 1.6056 0.7971 3634659 CHDI2_001442 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B22 compound treatment 156520.0 18700.0 0.5 217640.0 79200.0 2.14 1.8694 0.8489 3634661 CHDI2_001443 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B23 mock treatment 160760.0 22900.0 0.61 191440.0 53000.0 1.44 1.448 0.9279 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 B24 mock treatment 178040.0 40200.0 1.07 212160.0 73700.0 2.0 2.1715 0.9578 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C01 compound treatment 42560.0 -95300.0 -2.55 32920.0 -105000.0 -2.86 -3.8222 -0.9984 3554029 CHDI2_001444 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C02 compound treatment 8800.0 -129000.0 -3.45 9280.0 -129000.0 -3.5 -4.9133 -1.0 3634663 CHDI2_001445 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C03 compound treatment 107360.0 -30500.0 -0.82 112520.0 -25900.0 -0.7 -1.0728 -0.9971 3551993 CHDI2_001446 Oc1ccc(Br)cc1/C=N/NC(=O)c2ccccc2O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C04 compound treatment 124000.0 -13900.0 -0.37 119720.0 -18700.0 -0.51 -0.6202 -0.9883 3634665 CHDI2_001447 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C05 compound treatment 163040.0 25200.0 0.67 151400.0 13000.0 0.35 0.7246 0.954 3552272 CHDI2_001448 Oc1ccccc1C(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C06 compound treatment 11560.0 -126000.0 -3.38 9800.0 -129000.0 -3.48 -4.8512 -0.9999 3634667 CHDI2_001449 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OC/C=C/COc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C07 compound treatment 82320.0 -55500.0 -1.49 77840.0 -60600.0 -1.64 -2.2103 -0.9988 3552490 CHDI2_001450 Oc1ccc(Br)cc1/C=N/NC(=O)c2ccccn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C08 compound treatment 9080.0 -129000.0 -3.44 8320.0 -130000.0 -3.52 -4.9264 -0.9999 3634669 CHDI2_001451 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C09 compound treatment 12600.0 -125000.0 -3.35 8840.0 -130000.0 -3.51 -4.8499 -0.9997 3634671 CHDI2_001452 CN(CC=C)CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C10 compound treatment 134520.0 -3350.0 -0.09 143560.0 5140.0 0.14 0.0351 0.2123 3634672 CHDI2_001453 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C11 compound treatment 10600.0 -127000.0 -3.4 9560.0 -129000.0 -3.49 -4.8739 -0.9999 3634674 CHDI2_001454 OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)O)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C12 compound treatment 10880.0 -127000.0 -3.4 10200.0 -128000.0 -3.47 -4.8564 -0.9999 3634675 CHDI2_001455 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C13 compound treatment 141480.0 3610.0 0.1 188240.0 49800.0 1.35 1.0221 0.7559 3614424 CHDI2_001456 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C14 compound treatment 116680.0 -21200.0 -0.57 137040.0 -1380.0 -0.04 -0.4271 -0.7521 3634677 CHDI2_001457 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C15 compound treatment 141520.0 3650.0 0.1 144760.0 6340.0 0.17 0.1905 0.9644 3614530 CHDI2_001458 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C16 compound treatment 13640.0 -124000.0 -3.32 11400.0 -127000.0 -3.44 -4.7812 -0.9999 3634679 CHDI2_001459 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C17 compound treatment 132360.0 -5510.0 -0.15 138760.0 341.0 0.01 -0.0976 -0.6615 3614464 CHDI2_001460 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C18 compound treatment 123600.0 -14300.0 -0.38 140080.0 1660.0 0.04 -0.238 -0.6195 3634681 CHDI2_001461 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C19 compound treatment 124080.0 -13800.0 -0.37 150520.0 12100.0 0.33 -0.0291 -0.059 3614594 CHDI2_001462 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C20 compound treatment 145840.0 7970.0 0.21 153320.0 14900.0 0.4 0.4361 0.9556 3634683 CHDI2_001463 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C21 compound treatment 13160.0 -125000.0 -3.34 12520.0 -126000.0 -3.41 -4.7688 -0.9999 3614389 CHDI2_001464 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C22 compound treatment 136760.0 -1110.0 -0.03 150040.0 11600.0 0.31 0.2015 0.6378 3634685 CHDI2_001465 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C23 mock treatment 133480.0 -4390.0 -0.12 166040.0 27600.0 0.75 0.4458 0.589 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 C24 mock treatment 145920.0 8050.0 0.22 167640.0 29200.0 0.79 0.7117 0.8681 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D01 compound treatment 148400.0 10500.0 0.28 140520.0 2100.0 0.06 0.2395 0.833 3634687 CHDI2_001466 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D02 compound treatment 151600.0 13700.0 0.37 140880.0 2460.0 0.07 0.3069 0.8219 3634689 CHDI2_001467 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D03 compound treatment 171720.0 33900.0 0.91 188200.0 49800.0 1.35 1.5933 0.9813 3634691 CHDI2_001468 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D04 compound treatment 130680.0 -7190.0 -0.19 159680.0 21300.0 0.58 0.2711 0.4467 3634693 CHDI2_001469 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D05 compound treatment 195720.0 57900.0 1.55 169720.0 31300.0 0.85 1.6935 0.9598 3634695 CHDI2_001470 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D06 compound treatment 150640.0 12800.0 0.34 157840.0 19400.0 0.53 0.6134 0.9782 3634697 CHDI2_001471 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D07 compound treatment 173720.0 35900.0 0.96 167640.0 29200.0 0.79 1.2375 0.9954 3634699 CHDI2_001472 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D08 compound treatment 128280.0 -9590.0 -0.26 136480.0 -1940.0 -0.05 -0.2184 -0.8346 3634701 CHDI2_001473 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D09 compound treatment 132960.0 -4910.0 -0.13 167680.0 29300.0 0.79 0.4674 0.582 3634703 CHDI2_001474 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D10 compound treatment 117680.0 -20200.0 -0.54 140920.0 2500.0 0.07 -0.3339 -0.6136 3634705 CHDI2_001475 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D11 compound treatment 144280.0 6410.0 0.17 176560.0 38100.0 1.03 0.8515 0.8134 3634707 CHDI2_001476 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D12 compound treatment 127640.0 -10200.0 -0.27 146880.0 8460.0 0.23 -0.0314 -0.0881 3634709 CHDI2_001477 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D13 compound treatment 168360.0 30500.0 0.82 144080.0 5660.0 0.15 0.6851 0.8255 3634711 CHDI2_001478 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D14 compound treatment 123360.0 -14500.0 -0.39 127640.0 -10800.0 -0.29 -0.4807 -0.9901 3634713 CHDI2_001479 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D15 compound treatment 181160.0 43300.0 1.16 152000.0 13600.0 0.37 1.0789 0.8879 3634715 CHDI2_001480 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D16 compound treatment 152120.0 14300.0 0.38 127320.0 -11100.0 -0.3 0.0571 0.1177 3634717 CHDI2_001481 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D17 compound treatment 163920.0 26100.0 0.7 156720.0 18300.0 0.5 0.8431 0.986 3634719 CHDI2_001482 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D18 compound treatment 130400.0 -7470.0 -0.2 147480.0 9060.0 0.25 0.0322 0.1019 3634721 CHDI2_001483 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D19 compound treatment 209440.0 71600.0 1.91 164160.0 25700.0 0.7 1.8465 0.9063 3634723 CHDI2_001484 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D20 compound treatment 143160.0 5290.0 0.14 126440.0 -12000.0 -0.32 -0.1292 -0.3651 3634725 CHDI2_001485 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D21 compound treatment 185600.0 47700.0 1.28 166320.0 27900.0 0.76 1.437 0.9686 3634727 CHDI2_001486 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D22 compound treatment 158680.0 20800.0 0.56 187280.0 48900.0 1.32 1.329 0.926 3634729 CHDI2_001487 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D23 mock treatment 162280.0 24400.0 0.65 177000.0 38600.0 1.04 1.2003 0.9744 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 D24 mock treatment 140720.0 2850.0 0.08 151040.0 12600.0 0.34 0.2956 0.8443 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E01 compound treatment 128320.0 -9550.0 -0.26 130960.0 -7460.0 -0.2 -0.3233 -0.9933 3554048 CHDI2_001488 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2nccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E02 compound treatment 125280.0 -12600.0 -0.34 111280.0 -27100.0 -0.73 -0.7576 -0.9374 3634731 CHDI2_001489 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E03 compound treatment 140000.0 2130.0 0.06 149440.0 11000.0 0.3 0.2513 0.8274 3552029 CHDI2_001490 OC(=O)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E04 compound treatment 130120.0 -7750.0 -0.21 125640.0 -12800.0 -0.35 -0.3911 -0.9699 3634733 CHDI2_001491 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E05 compound treatment 139920.0 2050.0 0.05 131720.0 -6700.0 -0.18 -0.0894 -0.4717 3552300 CHDI2_001492 Oc1ccccc1C(=O)N/N=C/c2nccs2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E06 compound treatment 138320.0 454.0 0.01 138120.0 -299.0 -0.01 0.0029 0.1959 3634735 CHDI2_001493 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E07 compound treatment 117120.0 -20700.0 -0.55 116800.0 -21600.0 -0.59 -0.8063 -0.9996 3552525 CHDI2_001494 OC(=O)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E08 compound treatment 12000.0 -126000.0 -3.37 13240.0 -125000.0 -3.39 -4.777 -1.0 3634737 CHDI2_001495 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E09 compound treatment 9760.0 -128000.0 -3.43 9760.0 -129000.0 -3.48 -4.886 -1.0 3634739 CHDI2_001496 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3)Cc4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E10 compound treatment 120440.0 -17400.0 -0.47 123240.0 -15200.0 -0.41 -0.6202 -0.998 3634740 CHDI2_001497 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E11 compound treatment 23520.0 -114000.0 -3.06 26240.0 -112000.0 -3.04 -4.3102 -1.0 3634742 CHDI2_001498 CN(C[C@H]1C[C@H](OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccc(CO)cc3)Cc4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E12 compound treatment 127400.0 -10500.0 -0.28 126000.0 -12400.0 -0.34 -0.4357 -0.9959 3634743 CHDI2_001499 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E13 compound treatment 126440.0 -11400.0 -0.31 116800.0 -21600.0 -0.59 -0.63 -0.9541 3614478 CHDI2_001500 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E14 compound treatment 129360.0 -8510.0 -0.23 130640.0 -7780.0 -0.21 -0.3098 -0.9993 3634745 CHDI2_001501 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E15 compound treatment 133920.0 -3950.0 -0.11 120680.0 -17700.0 -0.48 -0.4142 -0.8424 3614432 CHDI2_001502 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E16 compound treatment 145120.0 7250.0 0.19 126280.0 -12100.0 -0.33 -0.0952 -0.2494 3634747 CHDI2_001503 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E17 compound treatment 146000.0 8130.0 0.22 131040.0 -7380.0 -0.2 0.0126 0.0426 3614467 CHDI2_001504 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E18 compound treatment 137080.0 -786.0 -0.02 130120.0 -8300.0 -0.22 -0.1737 -0.7699 3634749 CHDI2_001505 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E19 compound treatment 127920.0 -9950.0 -0.27 125400.0 -13000.0 -0.35 -0.4373 -0.9904 3614596 CHDI2_001506 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E20 compound treatment 144920.0 7050.0 0.19 150080.0 11700.0 0.32 0.3566 0.9697 3634751 CHDI2_001507 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E21 compound treatment 152800.0 14900.0 0.4 160840.0 22400.0 0.61 0.7117 0.9794 3614386 CHDI2_001508 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E22 compound treatment 141840.0 3970.0 0.11 145120.0 6700.0 0.18 0.2034 0.9676 3634753 CHDI2_001509 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E23 mock treatment 138520.0 654.0 0.02 128400.0 -10000.0 -0.27 -0.1794 -0.6601 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 E24 mock treatment 133720.0 -4150.0 -0.11 135000.0 -3420.0 -0.09 -0.1439 -0.996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F01 compound treatment 163560.0 25700.0 0.69 152720.0 14300.0 0.39 0.7597 0.9631 3634755 CHDI2_001510 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F02 compound treatment 171800.0 33900.0 0.91 159800.0 21400.0 0.58 1.0511 0.9764 3634757 CHDI2_001511 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F03 compound treatment 157960.0 20100.0 0.54 150360.0 11900.0 0.32 0.6086 0.9704 3634759 CHDI2_001512 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F04 compound treatment 136520.0 -1350.0 -0.04 131000.0 -7420.0 -0.2 -0.1675 -0.8208 3634761 CHDI2_001513 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F05 compound treatment 172880.0 35000.0 0.94 160000.0 21600.0 0.58 1.0754 0.9742 3634763 CHDI2_001514 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F06 compound treatment 154760.0 16900.0 0.45 136920.0 -1500.0 -0.04 0.2908 0.641 3634765 CHDI2_001515 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F07 compound treatment 127640.0 -10200.0 -0.27 121920.0 -16500.0 -0.45 -0.5093 -0.9723 3634767 CHDI2_001516 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F08 compound treatment 124000.0 -13900.0 -0.37 124280.0 -14100.0 -0.38 -0.5329 -0.9999 3634769 CHDI2_001517 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F09 compound treatment 140160.0 2290.0 0.06 147880.0 9460.0 0.26 0.2245 0.8524 3634771 CHDI2_001518 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F10 compound treatment 137160.0 -706.0 -0.02 130080.0 -8340.0 -0.23 -0.173 -0.7636 3634773 CHDI2_001519 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F11 compound treatment 125000.0 -12900.0 -0.34 133480.0 -4940.0 -0.13 -0.3379 -0.9152 3634775 CHDI2_001520 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F12 compound treatment 147040.0 9170.0 0.25 126760.0 -11700.0 -0.32 -0.0497 -0.1242 3634777 CHDI2_001521 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F13 compound treatment 12440.0 -125000.0 -3.35 11440.0 -127000.0 -3.44 -4.8031 -0.9999 3634779 CHDI2_001522 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F14 compound treatment 134600.0 -3270.0 -0.09 124360.0 -14100.0 -0.38 -0.3309 -0.8474 3634781 CHDI2_001523 COc1cc(OC/C=C/COc2cc(OC)c(\C=N\NC(=O)CCCCC(=O)NO)c(OC)c2)cc(OC)c1\C=N\NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F15 compound treatment 14800.0 -123000.0 -3.29 13320.0 -125000.0 -3.39 -4.7225 -0.9999 3634783 CHDI2_001524 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F16 compound treatment 126800.0 -11100.0 -0.3 135400.0 -3020.0 -0.08 -0.2671 -0.8698 3634785 CHDI2_001525 COc1cc(OCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F17 compound treatment 23920.0 -114000.0 -3.05 16640.0 -122000.0 -3.3 -4.4864 -0.9992 3634787 CHDI2_001526 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F18 compound treatment 126520.0 -11300.0 -0.3 123200.0 -15200.0 -0.41 -0.5059 -0.9887 3634789 CHDI2_001527 COc1cc(OCCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F19 compound treatment 137440.0 -426.0 -0.01 129720.0 -8700.0 -0.24 -0.1746 -0.7404 3634791 CHDI2_001528 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F20 compound treatment 129480.0 -8390.0 -0.22 108640.0 -29800.0 -0.81 -0.7287 -0.8708 3634793 CHDI2_001529 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OC\C=C\COc2c(OC)cc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F21 compound treatment 137680.0 -186.0 0.0 132840.0 -5580.0 -0.15 -0.1103 -0.73 3634795 CHDI2_001530 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F22 compound treatment 136720.0 -1150.0 -0.03 116920.0 -21500.0 -0.58 -0.4332 -0.7433 3634797 CHDI2_001531 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F23 mock treatment 145000.0 7130.0 0.19 152560.0 14100.0 0.38 0.4056 0.9483 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 F24 mock treatment 145000.0 7130.0 0.19 127880.0 -10500.0 -0.29 -0.0668 -0.1947 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G01 compound treatment 124000.0 -13900.0 -0.37 120600.0 -17800.0 -0.48 -0.6034 -0.9916 3554086 CHDI2_001532 NC(=O)COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G02 compound treatment 121440.0 -16400.0 -0.44 118840.0 -19600.0 -0.53 -0.6855 -0.9957 3634799 CHDI2_001533 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G03 compound treatment 128640.0 -9230.0 -0.25 128880.0 -9540.0 -0.26 -0.3571 -0.9997 3552065 CHDI2_001534 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G04 compound treatment 126400.0 -11500.0 -0.31 117720.0 -20700.0 -0.56 -0.6131 -0.9598 3634801 CHDI2_001535 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G05 compound treatment 122840.0 -15000.0 -0.4 127040.0 -11400.0 -0.31 -0.502 -0.9914 3552337 CHDI2_001536 NC(=O)COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G06 compound treatment 142200.0 4330.0 0.12 114520.0 -23900.0 -0.65 -0.3755 -0.5713 3634803 CHDI2_001537 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G07 compound treatment 11560.0 -126000.0 -3.38 11360.0 -127000.0 -3.44 -4.8213 -1.0 3552561 CHDI2_001538 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G08 compound treatment 100080.0 -37800.0 -1.01 105200.0 -33200.0 -0.9 -1.3506 -0.9983 3634805 CHDI2_001539 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G09 compound treatment 10720.0 -127000.0 -3.4 9840.0 -129000.0 -3.48 -4.8663 -0.9999 3634807 CHDI2_001540 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(OC(O2)c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G10 compound treatment 111080.0 -26800.0 -0.72 117200.0 -21200.0 -0.57 -0.9128 -0.994 3634808 CHDI2_001541 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G11 compound treatment 88160.0 -49700.0 -1.33 84960.0 -53500.0 -1.45 -1.9635 -0.9991 3634810 CHDI2_001542 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)c2ccc(NC(=O)CCCC#C)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G12 compound treatment 116720.0 -21100.0 -0.57 121200.0 -17200.0 -0.47 -0.7296 -0.9954 3634811 CHDI2_001543 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G13 compound treatment 119680.0 -18200.0 -0.49 120120.0 -18300.0 -0.5 -0.6943 -1.0 3614494 CHDI2_001544 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G14 compound treatment 110560.0 -27300.0 -0.73 122160.0 -16300.0 -0.44 -0.8277 -0.9706 3634813 CHDI2_001545 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G15 compound treatment 117240.0 -20600.0 -0.55 116880.0 -21500.0 -0.58 -0.8025 -0.9996 3614437 CHDI2_001546 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G16 compound treatment 106520.0 -31300.0 -0.84 115320.0 -23100.0 -0.63 -1.0351 -0.9896 3634815 CHDI2_001547 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G17 compound treatment 115960.0 -21900.0 -0.59 113400.0 -25000.0 -0.68 -0.8933 -0.9974 3614479 CHDI2_001548 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G18 compound treatment 121040.0 -16800.0 -0.45 113080.0 -25300.0 -0.69 -0.8033 -0.9791 3634817 CHDI2_001549 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G19 compound treatment 135160.0 -2710.0 -0.07 128280.0 -10100.0 -0.27 -0.2453 -0.864 3614693 CHDI2_001550 COC(=O)c1cn(CC(=O)O)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G20 compound treatment 119800.0 -18100.0 -0.48 126080.0 -12300.0 -0.33 -0.5779 -0.9837 3634819 CHDI2_001551 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G21 compound treatment 9040.0 -129000.0 -3.45 9800.0 -129000.0 -3.48 -4.8988 -1.0 3614403 CHDI2_001552 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G22 compound treatment 118200.0 -19700.0 -0.53 119480.0 -18900.0 -0.51 -0.7345 -0.9999 3634821 CHDI2_001553 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G23 mock treatment 128520.0 -9350.0 -0.25 126240.0 -12200.0 -0.33 -0.4099 -0.9907 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 G24 mock treatment 132200.0 -5670.0 -0.15 129600.0 -8820.0 -0.24 -0.276 -0.9759 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H01 compound treatment 138560.0 694.0 0.02 140240.0 1820.0 0.05 0.048 0.911 3634823 CHDI2_001554 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H02 compound treatment 170080.0 32200.0 0.86 132640.0 -5780.0 -0.16 0.4987 0.5694 3634825 CHDI2_001555 COc1cc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCC(=O)NO)c(OC)c2)ccc1\C=N\NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H03 compound treatment 151440.0 13600.0 0.36 159600.0 21200.0 0.57 0.6622 0.9757 3634827 CHDI2_001556 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H04 compound treatment 170920.0 33100.0 0.88 127400.0 -11000.0 -0.3 0.4143 0.4439 3634829 CHDI2_001557 COc1cc(OCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H05 compound treatment 142760.0 4890.0 0.13 145720.0 7300.0 0.2 0.2323 0.98 3634831 CHDI2_001558 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H06 compound treatment 132400.0 -5470.0 -0.15 121160.0 -17300.0 -0.47 -0.4338 -0.886 3634833 CHDI2_001559 COc1cc(OCCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H07 compound treatment 114000.0 -23900.0 -0.64 126920.0 -11500.0 -0.31 -0.6715 -0.9455 3634835 CHDI2_001560 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H08 compound treatment 116240.0 -21600.0 -0.58 124160.0 -14300.0 -0.39 -0.682 -0.9807 3634837 CHDI2_001561 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccc(COc3ccc(\C=N\NC(=O)CCCCC(=O)NO)cc3)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H09 compound treatment 88840.0 -49000.0 -1.31 90160.0 -48300.0 -1.31 -1.8511 -1.0 3634839 CHDI2_001562 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H10 compound treatment 114520.0 -23300.0 -0.62 117840.0 -20600.0 -0.56 -0.8355 -0.9984 3634841 CHDI2_001563 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2cccc(COc3ccc(\C=N\NC(=O)CCCCC(=O)NO)cc3)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H11 compound treatment 12960.0 -125000.0 -3.34 15560.0 -123000.0 -3.33 -4.7144 -1.0 3634843 CHDI2_001564 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H12 compound treatment 116040.0 -21800.0 -0.58 116400.0 -22000.0 -0.6 -0.8343 -0.9999 3634845 CHDI2_001565 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccccc2COc3ccc(\C=N\NC(=O)CCCCC(=O)NO)cc3)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H13 compound treatment 11560.0 -126000.0 -3.38 11640.0 -127000.0 -3.43 -4.8159 -1.0 3634847 CHDI2_001566 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H14 compound treatment 137080.0 -786.0 -0.02 128440.0 -9980.0 -0.27 -0.2059 -0.7598 3634849 CHDI2_001567 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccccc2c3ccccc3COc4ccc(\C=N\NC(=O)CCCCC(=O)NO)cc4)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H15 compound treatment 103000.0 -34900.0 -0.93 114000.0 -24400.0 -0.66 -1.1269 -0.9858 3634851 CHDI2_001568 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H16 compound treatment 136000.0 -1870.0 -0.05 146600.0 8180.0 0.22 0.1213 0.5344 3634853 CHDI2_001569 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H17 compound treatment 119600.0 -18300.0 -0.49 132400.0 -6020.0 -0.16 -0.4607 -0.8945 3634855 CHDI2_001570 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H18 compound treatment 121520.0 -16300.0 -0.44 121080.0 -17300.0 -0.47 -0.6411 -0.9994 3634857 CHDI2_001571 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H19 compound treatment 11000.0 -127000.0 -3.39 11440.0 -127000.0 -3.44 -4.8304 -1.0 3634859 CHDI2_001572 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H20 compound treatment 114640.0 -23200.0 -0.62 125440.0 -13000.0 -0.35 -0.6878 -0.9636 3634861 CHDI2_001573 Cc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c(O)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H21 compound treatment 8720.0 -129000.0 -3.45 9520.0 -129000.0 -3.49 -4.9102 -1.0 3634863 CHDI2_001574 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H22 compound treatment 130600.0 -7270.0 -0.19 138760.0 341.0 0.01 -0.1309 -0.6728 3634865 CHDI2_001575 Cc1cc(/C=N/NC(=O)CCCCCC(=O)NO)c(O)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H23 mock treatment 144560.0 6690.0 0.18 122680.0 -15700.0 -0.43 -0.1747 -0.3779 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 H24 mock treatment 122880.0 -15000.0 -0.4 122200.0 -16200.0 -0.44 -0.5939 -0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I01 compound treatment 90000.0 -47900.0 -1.28 98560.0 -39900.0 -1.08 -1.6684 -0.9964 3554221 CHDI2_001576 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCC#C)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I02 compound treatment 138200.0 334.0 0.01 127280.0 -11100.0 -0.3 -0.2069 -0.6858 3634867 CHDI2_001577 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I03 compound treatment 131600.0 -6270.0 -0.17 132240.0 -6180.0 -0.17 -0.2368 -1.0 1922557 CHDI2_001578 COc1ccc(/C=N/NC(=O)c2ccccc2O)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I04 compound treatment 115720.0 -22100.0 -0.59 120280.0 -18100.0 -0.49 -0.7661 -0.9957 3634869 CHDI2_001579 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I05 compound treatment 132440.0 -5430.0 -0.15 120280.0 -18100.0 -0.49 -0.4499 -0.8785 3552422 CHDI2_001580 Oc1ccccc1C(=O)N/N=C/c2ccc(OCC#C)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I06 compound treatment 160280.0 22400.0 0.6 130080.0 -8340.0 -0.23 0.2643 0.4126 3634871 CHDI2_001581 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I07 compound treatment 124960.0 -12900.0 -0.35 133200.0 -5220.0 -0.14 -0.344 -0.9223 3552599 CHDI2_001582 COc1ccc(/C=N/NC(=O)c2ccccn2)c(OC)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I08 compound treatment 71400.0 -66500.0 -1.78 70800.0 -67600.0 -1.83 -2.5516 -0.9999 3634873 CHDI2_001583 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I09 compound treatment 130320.0 -7550.0 -0.2 140840.0 2420.0 0.07 -0.0964 -0.4542 3634875 CHDI2_001584 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)NCCOCCOCCNC(=O)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I10 compound treatment 115560.0 -22300.0 -0.6 129920.0 -8500.0 -0.23 -0.5846 -0.9142 3634876 CHDI2_001585 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I11 compound treatment 20000.0 -118000.0 -3.15 18640.0 -120000.0 -3.24 -4.5223 -0.9999 468 CHDI2_001586 ONC(=O)CCCCCCC(=O)Nc1ccccc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I12 compound treatment 140200.0 2330.0 0.06 136400.0 -2020.0 -0.05 0.0055 0.0662 3634878 CHDI2_001587 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I13 compound treatment 113840.0 -24000.0 -0.64 125040.0 -13400.0 -0.36 -0.7106 -0.9632 3614495 CHDI2_001588 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I14 compound treatment 113280.0 -24600.0 -0.66 147480.0 9060.0 0.25 -0.2916 -0.4154 3634880 CHDI2_001589 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I15 compound treatment 99760.0 -38100.0 -1.02 107440.0 -31000.0 -0.84 -1.3138 -0.9953 3614442 CHDI2_001590 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I16 compound treatment 114680.0 -23200.0 -0.62 137960.0 -459.0 -0.01 -0.4473 -0.7211 3634882 CHDI2_001591 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I17 compound treatment 111480.0 -26400.0 -0.71 125240.0 -13200.0 -0.36 -0.7514 -0.9501 3614485 CHDI2_001592 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I18 compound treatment 120880.0 -17000.0 -0.45 131760.0 -6660.0 -0.18 -0.4488 -0.9181 3634884 CHDI2_001593 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I19 compound treatment 121800.0 -16100.0 -0.43 131680.0 -6740.0 -0.18 -0.4329 -0.9272 3614695 CHDI2_001594 COC(=O)c1cn(CCC(=O)O)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I20 compound treatment 141760.0 3890.0 0.1 142160.0 3740.0 0.1 0.1453 0.9999 3634886 CHDI2_001595 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I21 compound treatment 9040.0 -129000.0 -3.45 9880.0 -129000.0 -3.48 -4.8973 -1.0 3614398 CHDI2_001596 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I22 compound treatment 133400.0 -4470.0 -0.12 117600.0 -20800.0 -0.56 -0.483 -0.8383 3634888 CHDI2_001597 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I23 mock treatment 124320.0 -13500.0 -0.36 131920.0 -6500.0 -0.18 -0.3806 -0.945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 I24 mock treatment 140440.0 2570.0 0.07 131000.0 -7420.0 -0.2 -0.0933 -0.4396 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J01 compound treatment 141720.0 3850.0 0.1 141000.0 2580.0 0.07 0.1223 0.982 3634890 CHDI2_001598 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J02 compound treatment 141080.0 3210.0 0.09 140240.0 1820.0 0.05 0.0956 0.9651 3634892 CHDI2_001599 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J03 compound treatment 124680.0 -13200.0 -0.35 136120.0 -2300.0 -0.06 -0.2934 -0.8192 3634894 CHDI2_001600 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J04 compound treatment 171800.0 33900.0 0.91 159960.0 21500.0 0.58 1.0542 0.9771 3634896 CHDI2_001601 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J05 compound treatment 135840.0 -2030.0 -0.05 122680.0 -15700.0 -0.43 -0.3396 -0.7907 3634898 CHDI2_001602 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J06 compound treatment 132960.0 -4910.0 -0.13 129440.0 -8980.0 -0.24 -0.2647 -0.9581 3634900 CHDI2_001603 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J07 compound treatment 119320.0 -18500.0 -0.5 124440.0 -14000.0 -0.38 -0.6184 -0.9911 3634902 CHDI2_001604 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J08 compound treatment 113920.0 -23900.0 -0.64 109200.0 -29200.0 -0.79 -1.0123 -0.9945 3634904 CHDI2_001605 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J09 compound treatment 38680.0 -99200.0 -2.65 41560.0 -96900.0 -2.62 -3.7302 -1.0 3634906 CHDI2_001606 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J10 compound treatment 134000.0 -3870.0 -0.1 148600.0 10200.0 0.28 0.1218 0.4137 3634908 CHDI2_001607 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J11 compound treatment 147760.0 9890.0 0.26 156200.0 17800.0 0.48 0.5275 0.9603 3634910 CHDI2_001608 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J12 compound treatment 132640.0 -5230.0 -0.14 123440.0 -15000.0 -0.41 -0.3856 -0.8989 3634912 CHDI2_001609 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J13 compound treatment 11400.0 -126000.0 -3.38 11480.0 -127000.0 -3.44 -4.822 -1.0 3634914 CHDI2_001610 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J14 compound treatment 138200.0 334.0 0.01 136560.0 -1860.0 -0.05 -0.0293 -0.5726 3634916 CHDI2_001611 COc1cc(OC/C=C/COc2cc(OC)c(\C=N\NC(=O)CCCCCC(=O)NO)c(OC)c2)cc(OC)c1\C=N\NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J15 compound treatment 10320.0 -128000.0 -3.41 11400.0 -127000.0 -3.44 -4.844 -1.0 3634918 CHDI2_001612 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J16 compound treatment 115400.0 -22500.0 -0.6 121160.0 -17300.0 -0.47 -0.7553 -0.9923 3634920 CHDI2_001613 COc1cc(OCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J17 compound treatment 9480.0 -128000.0 -3.43 11320.0 -127000.0 -3.44 -4.8614 -1.0 3634922 CHDI2_001614 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J18 compound treatment 102880.0 -35000.0 -0.94 115880.0 -22500.0 -0.61 -1.0932 -0.9785 3634924 CHDI2_001615 COc1cc(OCCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J19 compound treatment 121360.0 -16500.0 -0.44 134360.0 -4060.0 -0.11 -0.3899 -0.857 3634926 CHDI2_001616 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J20 compound treatment 107880.0 -30000.0 -0.8 111760.0 -26700.0 -0.72 -1.0775 -0.9986 3634928 CHDI2_001617 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OC\C=C\COc2c(OC)cc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J21 compound treatment 75880.0 -62000.0 -1.66 91040.0 -47400.0 -1.28 -2.0794 -0.992 3634930 CHDI2_001618 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J22 compound treatment 119440.0 -18400.0 -0.49 125280.0 -13100.0 -0.36 -0.6 -0.9872 3634932 CHDI2_001619 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J23 mock treatment 137640.0 -226.0 -0.01 140160.0 1740.0 0.05 0.0291 0.6115 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 J24 mock treatment 137960.0 94.2 0.0 125360.0 -13100.0 -0.35 -0.2482 -0.702 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K01 compound treatment 128960.0 -8910.0 -0.24 130240.0 -8180.0 -0.22 -0.325 -0.9993 3552785 CHDI2_001620 CCCCCCC/C=N/NC(=O)c1ccccn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K02 compound treatment 142160.0 4290.0 0.11 133040.0 -5380.0 -0.15 -0.0218 -0.1173 3634934 CHDI2_001621 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K03 compound treatment 137600.0 -266.0 -0.01 119000.0 -19400.0 -0.53 -0.3768 -0.7166 3552859 CHDI2_001622 COc1cc(Br)c(/C=N/NC(=O)c2ccccn2)cc1OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K04 compound treatment 138360.0 494.0 0.01 130960.0 -7460.0 -0.2 -0.1334 -0.6594 3634936 CHDI2_001623 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K05 compound treatment 108840.0 -29000.0 -0.78 114520.0 -23900.0 -0.65 -1.0065 -0.9959 3552906 CHDI2_001624 COc1cc(/C=N/NC(=O)c2ccccn2)ccc1O 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K06 compound treatment 122880.0 -15000.0 -0.4 142440.0 4020.0 0.11 -0.2065 -0.4971 3634938 CHDI2_001625 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K07 compound treatment 129560.0 -8310.0 -0.22 129440.0 -8980.0 -0.24 -0.329 -0.999 3554243 CHDI2_001626 C/C(=N\NC(=O)c1ccccn1)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K08 compound treatment 128280.0 -9590.0 -0.26 155240.0 16800.0 0.46 0.1407 0.2692 3634940 CHDI2_001627 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K09 compound treatment 120400.0 -17500.0 -0.47 122520.0 -15900.0 -0.43 -0.6347 -0.9992 3634942 CHDI2_001628 ONC(=O)CCCCCCC(=O)Nc1cccc(c1)C(=O)NCCOCCOCCNC(=O)c2cccc(NC(=O)CCCCCCC(=O)NO)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K10 compound treatment 123320.0 -14500.0 -0.39 132400.0 -6020.0 -0.16 -0.3904 -0.9254 3634943 CHDI2_001629 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K11 compound treatment 106280.0 -31600.0 -0.84 100000.0 -38400.0 -1.04 -1.3329 -0.9947 3634945 CHDI2_001630 ONC(=O)/C=C/c1ccc(CN(CCC2=C[N]c3ccccc23)C(=O)CCCCC(=O)N(CCC4=C[N]c5ccccc45)Cc6ccc(\C=C\C(=O)NO)cc6)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K12 compound treatment 123640.0 -14200.0 -0.38 139480.0 1060.0 0.03 -0.2488 -0.6519 3634947 CHDI2_001631 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K13 compound treatment 114600.0 -23300.0 -0.62 122920.0 -15500.0 -0.42 -0.7368 -0.9816 3614498 CHDI2_001632 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K14 compound treatment 120200.0 -17700.0 -0.47 133680.0 -4740.0 -0.13 -0.4249 -0.8677 3634949 CHDI2_001633 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K15 compound treatment 116040.0 -21800.0 -0.58 131200.0 -7220.0 -0.2 -0.551 -0.895 3614446 CHDI2_001634 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K16 compound treatment 116800.0 -21100.0 -0.56 128360.0 -10100.0 -0.27 -0.591 -0.9443 3634951 CHDI2_001635 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K17 compound treatment 112720.0 -25100.0 -0.67 126920.0 -11500.0 -0.31 -0.6957 -0.9387 3614488 CHDI2_001636 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K18 compound treatment 114760.0 -23100.0 -0.62 124680.0 -13700.0 -0.37 -0.7 -0.9705 3634953 CHDI2_001637 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K19 compound treatment 9800.0 -128000.0 -3.43 11200.0 -127000.0 -3.44 -4.8576 -1.0 3614383 CHDI2_001638 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K20 compound treatment 113360.0 -24500.0 -0.66 133440.0 -4980.0 -0.13 -0.5588 -0.835 3634955 CHDI2_001639 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K21 compound treatment 123560.0 -14300.0 -0.38 136280.0 -2140.0 -0.06 -0.3115 -0.805 1917883 CHDI2_001640 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K22 compound treatment 120480.0 -17400.0 -0.47 118120.0 -20300.0 -0.55 -0.7174 -0.9965 3634957 CHDI2_001641 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K23 mock treatment 129920.0 -7950.0 -0.21 131440.0 -6980.0 -0.19 -0.2839 -0.9983 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 K24 mock treatment 130880.0 -6990.0 -0.19 140000.0 1580.0 0.04 -0.1019 -0.5314 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L01 compound treatment 122840.0 -15000.0 -0.4 135400.0 -3020.0 -0.08 -0.342 -0.8338 3634959 CHDI2_001642 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L02 compound treatment 145320.0 7450.0 0.2 143600.0 5180.0 0.14 0.2402 0.9852 3634961 CHDI2_001643 COc1cc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)c(OC)c2)ccc1\C=N\NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L03 compound treatment 10520.0 -127000.0 -3.41 11880.0 -127000.0 -3.43 -4.831 -1.0 3634963 CHDI2_001644 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L04 compound treatment 141440.0 3570.0 0.1 159680.0 21300.0 0.58 0.4746 0.8134 3634965 CHDI2_001645 COc1cc(OCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L05 compound treatment 100960.0 -36900.0 -0.99 93120.0 -45300.0 -1.23 -1.5652 -0.9942 3634967 CHDI2_001646 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L06 compound treatment 143840.0 5970.0 0.16 135840.0 -2580.0 -0.07 0.0636 0.3648 3634969 CHDI2_001647 COc1cc(OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L07 compound treatment 119160.0 -18700.0 -0.5 130720.0 -7700.0 -0.21 -0.5012 -0.9247 3634971 CHDI2_001648 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L08 compound treatment 120560.0 -17300.0 -0.46 136280.0 -2140.0 -0.06 -0.3683 -0.7894 3634973 CHDI2_001649 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccc(COc3ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc3)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L09 compound treatment 9440.0 -128000.0 -3.44 11600.0 -127000.0 -3.43 -4.8568 -1.0 3634975 CHDI2_001650 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L10 compound treatment 124520.0 -13300.0 -0.36 141280.0 2860.0 0.08 -0.1977 -0.5411 3634977 CHDI2_001651 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2cccc(COc3ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc3)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L11 compound treatment 9520.0 -128000.0 -3.43 10120.0 -128000.0 -3.47 -4.8836 -1.0 3634979 CHDI2_001652 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L12 compound treatment 116280.0 -21600.0 -0.58 126120.0 -12300.0 -0.33 -0.6437 -0.9658 3634981 CHDI2_001653 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2COc3ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc3)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L13 compound treatment 9760.0 -128000.0 -3.43 11240.0 -127000.0 -3.44 -4.8576 -1.0 3634983 CHDI2_001654 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L14 compound treatment 128360.0 -9510.0 -0.25 132560.0 -5860.0 -0.16 -0.292 -0.9742 3634985 CHDI2_001655 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2c3ccccc3COc4ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc4)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L15 compound treatment 77280.0 -60600.0 -1.62 106840.0 -31600.0 -0.85 -1.7505 -0.9553 3634987 CHDI2_001656 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L16 compound treatment 113360.0 -24500.0 -0.66 132880.0 -5540.0 -0.15 -0.5695 -0.847 3634989 CHDI2_001657 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(\C=N\NC(=O)CCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L17 compound treatment 49160.0 -88700.0 -2.37 75840.0 -62600.0 -1.69 -2.8758 -0.9864 3634991 CHDI2_001658 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L18 compound treatment 116520.0 -21300.0 -0.57 121320.0 -17100.0 -0.46 -0.7311 -0.9946 3634993 CHDI2_001659 Cc1cc(/C=N/NC(=O)CCCCC(=O)NO)c(O)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L19 compound treatment 120320.0 -17500.0 -0.47 124520.0 -13900.0 -0.38 -0.5979 -0.994 3634995 CHDI2_001660 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L20 compound treatment 118200.0 -19700.0 -0.53 132640.0 -5780.0 -0.16 -0.4826 -0.8794 3634997 CHDI2_001661 ONC(=O)CCCCC(=O)N/N=C/c1ccc(\C=N\NC(=O)CCCCC(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L21 compound treatment 96640.0 -41200.0 -1.1 102600.0 -35800.0 -0.97 -1.4654 -0.9979 3634999 CHDI2_001662 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L22 compound treatment 129840.0 -8030.0 -0.21 120040.0 -18400.0 -0.5 -0.5036 -0.9294 3635001 CHDI2_001663 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OCCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L23 mock treatment 136000.0 -1870.0 -0.05 121240.0 -17200.0 -0.47 -0.3642 -0.7785 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 L24 mock treatment 123160.0 -14700.0 -0.39 137040.0 -1380.0 -0.04 -0.3046 -0.7708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M01 compound treatment 44440.0 -93400.0 -2.5 53560.0 -84900.0 -2.3 -3.3916 -0.9991 3554166 CHDI2_001664 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M02 compound treatment 153000.0 15100.0 0.4 121200.0 -17200.0 -0.47 -0.0434 -0.0703 3635003 CHDI2_001665 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M03 compound treatment 124120.0 -13700.0 -0.37 126080.0 -12300.0 -0.33 -0.4962 -0.9989 1922299 CHDI2_001666 Oc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M04 compound treatment 132640.0 -5230.0 -0.14 140600.0 2180.0 0.06 -0.0571 -0.3763 3635005 CHDI2_001667 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M05 compound treatment 121480.0 -16400.0 -0.44 125200.0 -13200.0 -0.36 -0.563 -0.9949 3552393 CHDI2_001668 Oc1ccccc1C(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M06 compound treatment 119440.0 -18400.0 -0.49 129040.0 -9380.0 -0.25 -0.5281 -0.9524 3635007 CHDI2_001669 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M07 compound treatment 109400.0 -28500.0 -0.76 108000.0 -30400.0 -0.82 -1.1207 -0.9992 3552669 CHDI2_001670 Oc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M08 compound treatment 113920.0 -23900.0 -0.64 130040.0 -8380.0 -0.23 -0.6133 -0.9026 3635009 CHDI2_001671 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M09 compound treatment 9240.0 -129000.0 -3.44 10640.0 -128000.0 -3.46 -4.879 -1.0 3635011 CHDI2_001672 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)c2ccccc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M10 compound treatment 123000.0 -14900.0 -0.4 128720.0 -9700.0 -0.26 -0.4669 -0.9797 3635012 CHDI2_001673 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M11 compound treatment 8680.0 -129000.0 -3.46 10320.0 -128000.0 -3.47 -4.8957 -1.0 3635014 CHDI2_001674 ONC(=O)/C=C/c1ccc(CNCCC2=C[N]c3ccccc23)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M12 compound treatment 139160.0 1290.0 0.03 119560.0 -18900.0 -0.51 -0.3365 -0.6577 3635016 CHDI2_001675 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M13 compound treatment 126080.0 -11800.0 -0.32 124920.0 -13500.0 -0.37 -0.4813 -0.9973 3614499 CHDI2_001676 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M14 compound treatment 102920.0 -34900.0 -0.93 137120.0 -1300.0 -0.04 -0.6858 -0.7332 3635018 CHDI2_001677 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M15 compound treatment 106920.0 -30900.0 -0.83 131360.0 -7060.0 -0.19 -0.7205 -0.8481 3614451 CHDI2_001678 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M16 compound treatment 120080.0 -17800.0 -0.48 135840.0 -2580.0 -0.07 -0.3858 -0.8023 3635020 CHDI2_001679 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M17 compound treatment 120280.0 -17600.0 -0.47 128960.0 -9460.0 -0.26 -0.5137 -0.9591 3614488 CHDI2_001680 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M18 compound treatment 105720.0 -32100.0 -0.86 120200.0 -18200.0 -0.49 -0.9568 -0.9652 3635022 CHDI2_001681 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M19 compound treatment 8000.0 -130000.0 -3.47 9960.0 -128000.0 -3.48 -4.9154 -1.0 3614396 CHDI2_001682 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M20 compound treatment 120880.0 -17000.0 -0.45 124800.0 -13600.0 -0.37 -0.582 -0.9946 3635024 CHDI2_001683 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M21 compound treatment 123480.0 -14400.0 -0.38 141600.0 3180.0 0.09 -0.2112 -0.5356 3614688 CHDI2_001684 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M22 compound treatment 121680.0 -16200.0 -0.43 131680.0 -6740.0 -0.18 -0.4352 -0.9262 3635026 CHDI2_001685 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M23 mock treatment 135440.0 -2430.0 -0.06 150960.0 12500.0 0.34 0.1942 0.5618 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 M24 mock treatment 122800.0 -15100.0 -0.4 139520.0 1100.0 0.03 -0.2639 -0.653 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N01 compound treatment 145600.0 7730.0 0.21 146320.0 7900.0 0.21 0.2975 0.9999 3635028 CHDI2_001686 Cc1cc(/C=N/NC(=O)CCCCC(=O)Nc2ccccc2O)c(O)c(/C=N/NC(=O)CCCCC(=O)Nc3ccccc3O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N02 compound treatment 151800.0 13900.0 0.37 159360.0 20900.0 0.57 0.6644 0.9793 3635030 CHDI2_001687 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N03 compound treatment 119120.0 -18700.0 -0.5 153040.0 14600.0 0.4 -0.0747 -0.1169 3635032 CHDI2_001688 Cc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c(/C=N/NC(=O)CCCCCC(=O)Nc3ccccc3O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N04 compound treatment 129920.0 -7950.0 -0.21 145680.0 7260.0 0.2 -0.0113 -0.039 3635034 CHDI2_001689 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N05 compound treatment 129280.0 -8590.0 -0.23 131320.0 -7100.0 -0.19 -0.2983 -0.9961 3635036 CHDI2_001690 Cc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc3ccccc3O)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N06 compound treatment 144000.0 6130.0 0.16 143720.0 5300.0 0.14 0.2175 0.9978 3635038 CHDI2_001691 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N07 compound treatment 103040.0 -34800.0 -0.93 131880.0 -6540.0 -0.18 -0.7839 -0.8267 3635040 CHDI2_001692 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(\C=N\NC(=O)CCCCC(=O)Nc3ccccc3O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N08 compound treatment 118680.0 -19200.0 -0.51 134400.0 -4020.0 -0.11 -0.4398 -0.8384 3635042 CHDI2_001693 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N09 compound treatment 107560.0 -30300.0 -0.81 123960.0 -14500.0 -0.39 -0.85 -0.9442 3635044 CHDI2_001694 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(\C=N\NC(=O)CCCCCC(=O)Nc3ccccc3O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N10 compound treatment 121640.0 -16200.0 -0.43 123720.0 -14700.0 -0.4 -0.5883 -0.9991 3635046 CHDI2_001695 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N11 compound treatment 115560.0 -22300.0 -0.6 111120.0 -27300.0 -0.74 -0.9445 -0.9944 3635048 CHDI2_001696 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(\C=N\NC(=O)CCCCCCC(=O)Nc3ccccc3O)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N12 compound treatment 127040.0 -10800.0 -0.29 132000.0 -6420.0 -0.17 -0.3276 -0.9702 3635050 CHDI2_001697 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OCC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N13 compound treatment 7920.0 -130000.0 -3.48 8560.0 -130000.0 -3.52 -4.9437 -1.0 3635052 CHDI2_001698 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(\C=N\NC(=O)CCCCCCC(=O)NO)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N14 compound treatment 12760.0 -125000.0 -3.35 24160.0 -114000.0 -3.09 -4.5536 -0.9992 3635054 CHDI2_001699 COc1cc(OC/C=C/COc2cc(OC)c(\C=N\NC(=O)CCCCCCC(=O)NO)c(OC)c2)cc(OC)c1\C=N\NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N15 compound treatment 8160.0 -130000.0 -3.47 9680.0 -129000.0 -3.49 -4.9178 -1.0 3635056 CHDI2_001700 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OCCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N16 compound treatment 122520.0 -15300.0 -0.41 138960.0 541.0 0.01 -0.2799 -0.6815 3635058 CHDI2_001701 COc1cc(OCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N17 compound treatment 8480.0 -129000.0 -3.46 10320.0 -128000.0 -3.47 -4.8995 -1.0 3635060 CHDI2_001702 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OCCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N18 compound treatment 98400.0 -39500.0 -1.06 135040.0 -3380.0 -0.09 -0.8112 -0.7655 3635062 CHDI2_001703 COc1cc(OCCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N19 compound treatment 98560.0 -39300.0 -1.05 134360.0 -4060.0 -0.11 -0.8211 -0.7768 3635064 CHDI2_001704 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4o3)CC(O2)c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N20 compound treatment 31360.0 -107000.0 -2.85 12520.0 -126000.0 -3.41 -4.4246 -0.996 3635065 CHDI2_001705 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OC\C=C\COc2c(OC)cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N21 compound treatment 101360.0 -36500.0 -0.98 123600.0 -14800.0 -0.4 -0.9742 -0.9228 3215593 CHDI2_001706 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N22 compound treatment 10760.0 -127000.0 -3.4 15400.0 -123000.0 -3.33 -4.7591 -0.9999 3635067 CHDI2_001707 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N23 mock treatment 119120.0 -18700.0 -0.5 122280.0 -16100.0 -0.44 -0.6635 -0.9976 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 N24 mock treatment 151920.0 14100.0 0.38 134960.0 -3460.0 -0.09 0.1996 0.5152 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O01 compound treatment 124760.0 -13100.0 -0.35 158320.0 19900.0 0.54 0.1331 0.207 3554202 CHDI2_001708 CN(CCO)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O02 compound treatment 145720.0 7850.0 0.21 133360.0 -5060.0 -0.14 0.0517 0.2062 3635069 CHDI2_001709 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O03 compound treatment 108280.0 -29600.0 -0.79 120280.0 -18100.0 -0.49 -0.9068 -0.9737 3552203 CHDI2_001710 Oc1ccccc1C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O04 compound treatment 121600.0 -16300.0 -0.44 133560.0 -4860.0 -0.13 -0.4007 -0.8815 3635071 CHDI2_001711 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O05 compound treatment 124080.0 -13800.0 -0.37 120920.0 -17500.0 -0.47 -0.5957 -0.9923 3552412 CHDI2_001712 CN(CCO)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O06 compound treatment 115920.0 -21900.0 -0.59 140240.0 1820.0 0.05 -0.3802 -0.6455 3635073 CHDI2_001713 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O07 compound treatment 106360.0 -31500.0 -0.84 129960.0 -8460.0 -0.23 -0.7578 -0.8678 3552710 CHDI2_001714 Oc1c(Br)cc(/C=N/NC(=O)c2ccccn2)cc1Br 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O08 compound treatment 111320.0 -26500.0 -0.71 133080.0 -5340.0 -0.14 -0.6043 -0.8339 3635075 CHDI2_001715 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O09 compound treatment 6440.0 -131000.0 -3.52 8000.0 -130000.0 -3.53 -4.9825 -1.0 3635077 CHDI2_001716 OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O10 compound treatment 114400.0 -23500.0 -0.63 114600.0 -23800.0 -0.64 -0.8998 -0.9999 3635078 CHDI2_001717 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O11 compound treatment 14400.0 -123000.0 -3.3 13240.0 -125000.0 -3.39 -4.7316 -0.9999 3635080 CHDI2_001718 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O12 compound treatment 116600.0 -21300.0 -0.57 116480.0 -21900.0 -0.59 -0.8222 -0.9998 3635081 CHDI2_001719 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O13 compound treatment 105560.0 -32300.0 -0.86 102200.0 -36200.0 -0.98 -1.3044 -0.998 3614501 CHDI2_001720 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O14 compound treatment 103640.0 -34200.0 -0.92 119240.0 -19200.0 -0.52 -1.0145 -0.9639 3635083 CHDI2_001721 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O15 compound treatment 116200.0 -21700.0 -0.58 123480.0 -14900.0 -0.4 -0.6958 -0.9845 3614455 CHDI2_001722 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O16 compound treatment 124760.0 -13100.0 -0.35 135640.0 -2780.0 -0.08 -0.3011 -0.8398 3635085 CHDI2_001723 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O17 compound treatment 115000.0 -22900.0 -0.61 123680.0 -14700.0 -0.4 -0.7146 -0.9786 3614538 CHDI2_001724 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O18 compound treatment 115760.0 -22100.0 -0.59 137080.0 -1340.0 -0.04 -0.4438 -0.7491 3635087 CHDI2_001725 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O19 compound treatment 14920.0 -123000.0 -3.29 12160.0 -126000.0 -3.42 -4.7424 -0.9998 3614394 CHDI2_001726 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O20 compound treatment 125560.0 -12300.0 -0.33 127560.0 -10900.0 -0.29 -0.4406 -0.9984 3635089 CHDI2_001727 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O21 compound treatment 119160.0 -18700.0 -0.5 121200.0 -17200.0 -0.47 -0.6834 -0.9994 3614525 CHDI2_001728 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O22 compound treatment 105280.0 -32600.0 -0.87 117920.0 -20500.0 -0.55 -1.0088 -0.9762 3635091 CHDI2_001729 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O23 mock treatment 121640.0 -16200.0 -0.43 127080.0 -11300.0 -0.31 -0.524 -0.9856 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 O24 mock treatment 125960.0 -11900.0 -0.32 137040.0 -1380.0 -0.04 -0.2516 -0.7846 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P01 compound treatment 148680.0 10800.0 0.29 150760.0 12300.0 0.33 0.4408 0.9974 3635093 CHDI2_001730 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccc3)CC(O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P02 compound treatment 71760.0 -66100.0 -1.77 51320.0 -87100.0 -2.36 -2.9177 -0.9899 3635094 CHDI2_001731 COc1cc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)c(OC)c2)ccc1\C=N\NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P03 compound treatment 116200.0 -21700.0 -0.58 136080.0 -2340.0 -0.06 -0.4546 -0.7797 3215583 CHDI2_001732 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P04 compound treatment 51920.0 -85900.0 -2.3 54280.0 -84100.0 -2.28 -3.2363 -1.0 3635096 CHDI2_001733 COc1cc(OCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P05 compound treatment 117880.0 -20000.0 -0.53 130960.0 -7460.0 -0.2 -0.5208 -0.9114 3635098 CHDI2_001734 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P06 compound treatment 107480.0 -30400.0 -0.81 122960.0 -15500.0 -0.42 -0.8707 -0.9524 3635099 CHDI2_001735 COc1cc(OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P07 compound treatment 97720.0 -40100.0 -1.07 115160.0 -23300.0 -0.63 -1.2046 -0.9677 3635101 CHDI2_001736 CC(C)OCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P08 compound treatment 18280.0 -120000.0 -3.2 26880.0 -112000.0 -3.02 -4.3971 -0.9996 3635102 CHDI2_001737 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccc(COc3ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc3)cc2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P09 compound treatment 35080.0 -103000.0 -2.75 71560.0 -66900.0 -1.81 -3.224 -0.9794 3215599 CHDI2_001738 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P10 compound treatment 5960.0 -132000.0 -3.53 20360.0 -118000.0 -3.2 -4.7549 -0.9988 3635104 CHDI2_001739 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2cccc(COc3ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc3)c2)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P11 compound treatment 2840.0 -135000.0 -3.61 3480.0 -135000.0 -3.65 -5.1371 -1.0 3635106 CHDI2_001740 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(COc3ccccc3)CC(O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P12 compound treatment 3880.0 -134000.0 -3.58 3920.0 -134000.0 -3.64 -5.109 -1.0 3635107 CHDI2_001741 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2COc3ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc3)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P13 compound treatment 3640.0 -134000.0 -3.59 4120.0 -134000.0 -3.64 -5.1097 -1.0 3635109 CHDI2_001742 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@@H]2O[C@H](CSc3ccncc3)C[C@@H](O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P14 compound treatment 5640.0 -132000.0 -3.54 6160.0 -132000.0 -3.58 -5.0328 -1.0 3635110 CHDI2_001743 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2c3ccccc3COc4ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc4)cc1 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P15 compound treatment 102160.0 -35700.0 -0.96 116520.0 -21900.0 -0.59 -1.0946 -0.9737 3635112 CHDI2_001744 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@H]2O[C@@H](CSc3ccncc3)C[C@H](O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P16 compound treatment 45280.0 -92600.0 -2.48 72000.0 -66400.0 -1.8 -3.0227 -0.9876 3635113 CHDI2_001745 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCc2ccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc3OC)cc2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P17 compound treatment 105200.0 -32700.0 -0.87 113160.0 -25300.0 -0.68 -1.1014 -0.9926 3635115 CHDI2_001746 COCC1CC(OC(O1)c2ccc(cc2)C3OC(COC)CC(O3)c4ccc(NC(=O)CCCCCCC(=O)NO)cc4)c5ccc(NC(=O)CCCCCCC(=O)NO)cc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P18 compound treatment 108560.0 -29300.0 -0.78 109080.0 -29300.0 -0.79 -1.1159 -1.0 3635116 CHDI2_001747 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCc2cccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc3OC)c2 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P19 compound treatment 107480.0 -30400.0 -0.81 111720.0 -26700.0 -0.72 -1.0858 -0.9983 3215595 CHDI2_001748 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P20 compound treatment 52760.0 -85100.0 -2.28 64440.0 -74000.0 -2.0 -3.0259 -0.998 3635118 CHDI2_001749 COc1cc(OCc2ccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c3)cc2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P21 compound treatment 4040.0 -134000.0 -3.58 4960.0 -133000.0 -3.61 -5.086 -1.0 3635120 CHDI2_001750 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(Cc3ccccc3)Cc4ccccc4)CC(O2)c5ccccc5 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P22 compound treatment 10360.0 -128000.0 -3.41 15080.0 -123000.0 -3.34 -4.7728 -0.9999 3635121 CHDI2_001751 COc1cc(OCc2cccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c3)c2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P23 mock treatment 114880.0 -23000.0 -0.61 114200.0 -24200.0 -0.66 -0.8984 -0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.2407 P24 mock treatment 134080.0 -3790.0 -0.1 132240.0 -6180.0 -0.17 -0.1899 -0.9711 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A01 mock treatment 193760.0 47600.0 1.27 188760.0 42200.0 1.14 1.7078 0.9985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A02 mock treatment 180120.0 34000.0 0.91 207320.0 60700.0 1.64 1.8051 0.9609 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A03 mock treatment 197320.0 51200.0 1.37 221760.0 75200.0 2.04 2.4069 0.9813 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A04 mock treatment 182920.0 36800.0 0.98 170800.0 24200.0 0.66 1.159 0.9806 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A05 mock treatment 184120.0 38000.0 1.02 185480.0 38900.0 1.05 1.4627 0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A06 mock treatment 190760.0 44600.0 1.19 163400.0 16800.0 0.46 1.1656 0.9128 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A07 mock treatment 208200.0 62000.0 1.66 139600.0 -6980.0 -0.19 1.0399 0.6226 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A08 mock treatment 187960.0 41800.0 1.12 153320.0 6740.0 0.18 0.9197 0.8118 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A09 mock treatment 198720.0 52600.0 1.41 138520.0 -8060.0 -0.22 0.8399 0.5903 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A10 mock treatment 192240.0 46100.0 1.23 155720.0 9140.0 0.25 1.0466 0.8325 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A11 mock treatment 182440.0 36300.0 0.97 185520.0 38900.0 1.05 1.4317 0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A12 mock treatment 185760.0 39600.0 1.06 202400.0 55800.0 1.51 1.8176 0.9849 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A13 mock treatment 181960.0 35800.0 0.96 197200.0 50600.0 1.37 1.6462 0.9846 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A14 mock treatment 189000.0 42800.0 1.15 198840.0 52300.0 1.41 1.8107 0.9945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A15 mock treatment 193080.0 46900.0 1.26 177520.0 30900.0 0.84 1.4798 0.9807 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A16 mock treatment 201360.0 55200.0 1.48 155400.0 8820.0 0.24 1.2129 0.8109 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A17 mock treatment 199080.0 52900.0 1.42 160840.0 14300.0 0.39 1.274 0.8682 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A18 mock treatment 189560.0 43400.0 1.16 158880.0 12300.0 0.33 1.0564 0.8747 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A19 mock treatment 173600.0 27400.0 0.73 148360.0 1780.0 0.05 0.5531 0.7519 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A20 mock treatment 181520.0 35400.0 0.95 148120.0 1540.0 0.04 0.6983 0.7376 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A21 mock treatment 186600.0 40400.0 1.08 135600.0 -11000.0 -0.3 0.5547 0.4945 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A22 mock treatment 192800.0 46600.0 1.25 182720.0 36100.0 0.98 1.574 0.9928 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A23 mock treatment 195880.0 49700.0 1.33 147360.0 781.0 0.02 0.9554 0.7183 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base A24 mock treatment 192480.0 46300.0 1.24 171800.0 25200.0 0.68 1.3589 0.9606 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B01 mock treatment 193000.0 46800.0 1.25 175480.0 28900.0 0.78 1.4392 0.9743 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B02 mock treatment 186400.0 40200.0 1.08 161880.0 15300.0 0.41 1.054 0.9139 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B03 mock treatment 208040.0 61900.0 1.66 152440.0 5860.0 0.16 1.2826 0.7713 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B04 mock treatment 170800.0 24600.0 0.66 169680.0 23100.0 0.63 0.9083 0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B05 mock treatment 183080.0 36900.0 0.99 171720.0 25100.0 0.68 1.1796 0.9835 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B06 mock treatment 152640.0 6480.0 0.17 173960.0 27400.0 0.74 0.6467 0.8496 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B07 mock treatment 148560.0 2400.0 0.06 151560.0 4980.0 0.13 0.1408 0.9425 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B08 mock treatment 156920.0 10800.0 0.29 158320.0 11700.0 0.32 0.4283 0.9988 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B09 mock treatment 177040.0 30900.0 0.83 161600.0 15000.0 0.41 0.8716 0.9467 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B10 mock treatment 181200.0 35000.0 0.94 142920.0 -3660.0 -0.1 0.5927 0.6289 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B11 mock treatment 192720.0 46600.0 1.25 136120.0 -10500.0 -0.28 0.6804 0.5327 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B12 mock treatment 182280.0 36100.0 0.97 162440.0 15900.0 0.43 0.9868 0.9333 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B13 mock treatment 181040.0 34900.0 0.93 151400.0 4820.0 0.13 0.752 0.7982 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B14 mock treatment 184560.0 38400.0 1.03 143520.0 -3060.0 -0.08 0.6678 0.648 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B15 mock treatment 187920.0 41800.0 1.12 146560.0 -19.5 0.0 0.7895 0.7068 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B16 mock treatment 188320.0 42200.0 1.13 158240.0 11700.0 0.32 1.0207 0.8715 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B17 mock treatment 202400.0 56200.0 1.5 157200.0 10600.0 0.29 1.2671 0.8273 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B18 mock treatment 184720.0 38600.0 1.03 148520.0 1940.0 0.05 0.7665 0.7422 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B19 mock treatment 192520.0 46400.0 1.24 150960.0 4380.0 0.12 0.9608 0.7712 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B20 mock treatment 184040.0 37900.0 1.01 151160.0 4580.0 0.12 0.8042 0.7878 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B21 mock treatment 219120.0 73000.0 1.95 135880.0 -10700.0 -0.29 1.1752 0.5956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B22 mock treatment 176200.0 30000.0 0.8 148000.0 1420.0 0.04 0.5954 0.7401 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B23 mock treatment 182400.0 36200.0 0.97 142760.0 -3820.0 -0.1 0.6124 0.6281 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base B24 mock treatment 189240.0 43100.0 1.15 144880.0 -1700.0 -0.05 0.7823 0.6783 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C01 mock treatment 187040.0 40900.0 1.09 154440.0 7860.0 0.21 0.9237 0.8292 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C02 mock treatment 162520.0 16400.0 0.44 141480.0 -5100.0 -0.14 0.2118 0.4616 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C03 mock treatment 142040.0 -4120.0 -0.11 173320.0 26700.0 0.72 0.434 0.5927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C04 mock treatment 145680.0 -478.0 -0.01 162120.0 15500.0 0.42 0.2884 0.6853 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C05 mock treatment 153000.0 6840.0 0.18 144160.0 -2420.0 -0.07 0.0831 0.4275 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C06 mock treatment 146560.0 402.0 0.01 152440.0 5860.0 0.16 0.1198 0.7533 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C07 mock treatment 141920.0 -4240.0 -0.11 145680.0 -899.0 -0.02 -0.0974 -0.8398 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C08 mock treatment 150720.0 4560.0 0.12 162680.0 16100.0 0.44 0.3945 0.8715 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C09 mock treatment 134560.0 -11600.0 -0.31 155280.0 8700.0 0.24 -0.0528 -0.1356 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C10 mock treatment 140440.0 -5720.0 -0.15 163760.0 17200.0 0.47 0.2207 0.4508 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C11 mock treatment 141080.0 -5080.0 -0.14 157480.0 10900.0 0.3 0.1126 0.3467 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C12 mock treatment 153520.0 7360.0 0.2 138640.0 -7940.0 -0.21 -0.0127 -0.0437 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C13 mock treatment 154160.0 8000.0 0.21 149080.0 2500.0 0.07 0.1992 0.8874 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C14 mock treatment 145760.0 -398.0 -0.01 155440.0 8860.0 0.24 0.1621 0.675 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C15 mock treatment 158080.0 11900.0 0.32 143160.0 -3420.0 -0.09 0.16 0.4819 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C16 mock treatment 141080.0 -5080.0 -0.14 151160.0 4580.0 0.12 -0.0084 -0.0455 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C17 mock treatment 143720.0 -2440.0 -0.07 157680.0 11100.0 0.3 0.1664 0.541 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C18 mock treatment 140040.0 -6120.0 -0.16 152840.0 6260.0 0.17 0.0041 0.0175 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C19 mock treatment 142080.0 -4080.0 -0.11 140600.0 -5980.0 -0.16 -0.1916 -0.9815 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C20 mock treatment 150320.0 4160.0 0.11 148040.0 1460.0 0.04 0.1067 0.903 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C21 mock treatment 158160.0 12000.0 0.32 147200.0 621.0 0.02 0.2389 0.7431 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C22 mock treatment 156560.0 10400.0 0.28 154200.0 7620.0 0.21 0.3426 0.9892 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C23 mock treatment 175520.0 29400.0 0.79 131160.0 -15400.0 -0.42 0.2602 0.2925 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base C24 mock treatment 182120.0 36000.0 0.96 132840.0 -13700.0 -0.37 0.4172 0.4045 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D01 mock treatment 153160.0 7000.0 0.19 171320.0 24700.0 0.67 0.606 0.8714 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D02 mock treatment 143560.0 -2600.0 -0.07 186160.0 39600.0 1.07 0.7085 0.6599 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D03 mock treatment 160800.0 14600.0 0.39 181440.0 34900.0 0.94 0.9443 0.9241 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D04 mock treatment 194040.0 47900.0 1.28 172920.0 26300.0 0.71 1.4099 0.9618 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D05 mock treatment 184920.0 38800.0 1.04 189360.0 42800.0 1.16 1.5521 0.9985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D06 mock treatment 193520.0 47400.0 1.27 178640.0 32100.0 0.87 1.5095 0.983 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D07 mock treatment 157560.0 11400.0 0.3 168680.0 22100.0 0.6 0.6387 0.9511 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D08 mock treatment 163520.0 17400.0 0.46 197640.0 51100.0 1.38 1.3058 0.8955 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D09 mock treatment 154440.0 8280.0 0.22 197680.0 51100.0 1.38 1.1349 0.81 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D10 mock treatment 166840.0 20700.0 0.55 188960.0 42400.0 1.15 1.2025 0.944 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D11 mock treatment 152400.0 6240.0 0.17 203520.0 56900.0 1.54 1.2081 0.7791 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D12 mock treatment 177040.0 30900.0 0.83 169880.0 23300.0 0.63 1.0301 0.9911 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D13 mock treatment 171360.0 25200.0 0.67 175240.0 28700.0 0.78 1.0253 0.9975 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D14 mock treatment 159160.0 13000.0 0.35 177600.0 31000.0 0.84 0.8397 0.9238 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D15 mock treatment 170960.0 24800.0 0.66 153320.0 6740.0 0.18 0.5981 0.8693 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D16 mock treatment 159440.0 13300.0 0.36 178320.0 31700.0 0.86 0.8588 0.9236 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D17 mock treatment 156000.0 9840.0 0.26 182240.0 35700.0 0.97 0.8688 0.8682 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D18 mock treatment 162280.0 16100.0 0.43 171840.0 25300.0 0.68 0.7885 0.9753 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D19 mock treatment 169480.0 23300.0 0.62 202640.0 56100.0 1.52 1.5143 0.9228 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D20 mock treatment 149120.0 2960.0 0.08 189320.0 42700.0 1.16 0.8742 0.7538 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D21 mock treatment 162280.0 16100.0 0.43 163640.0 17100.0 0.46 0.6315 0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D22 mock treatment 153240.0 7080.0 0.19 161280.0 14700.0 0.4 0.4154 0.9424 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D23 mock treatment 172480.0 26300.0 0.7 151840.0 5260.0 0.14 0.5986 0.8333 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base D24 mock treatment 180360.0 34200.0 0.91 179240.0 32700.0 0.88 1.2721 0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E01 mock treatment 182160.0 36000.0 0.96 145120.0 -1460.0 -0.04 0.653 0.6775 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E02 mock treatment 159520.0 13400.0 0.36 162200.0 15600.0 0.42 0.5518 0.9965 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E03 mock treatment 138080.0 -8080.0 -0.22 160320.0 13700.0 0.37 0.1102 0.2563 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E04 mock treatment 143080.0 -3080.0 -0.08 141920.0 -4660.0 -0.13 -0.1474 -0.9786 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E05 mock treatment 151240.0 5080.0 0.14 159800.0 13200.0 0.36 0.3492 0.9121 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E06 mock treatment 134320.0 -11800.0 -0.32 160840.0 14300.0 0.39 0.0491 0.0983 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E07 mock treatment 132400.0 -13800.0 -0.37 135800.0 -10800.0 -0.29 -0.4666 -0.9934 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E08 mock treatment 130920.0 -15200.0 -0.41 153560.0 6980.0 0.19 -0.1546 -0.3441 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E09 mock treatment 139160.0 -7000.0 -0.19 159200.0 12600.0 0.34 0.1092 0.2804 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E10 mock treatment 132920.0 -13200.0 -0.35 153560.0 6980.0 0.19 -0.1168 -0.2909 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E11 mock treatment 146560.0 402.0 0.01 160680.0 14100.0 0.38 0.2775 0.7267 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E12 mock treatment 134480.0 -11700.0 -0.31 163640.0 17100.0 0.46 0.1057 0.1896 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E13 mock treatment 147120.0 962.0 0.03 137760.0 -8820.0 -0.24 -0.1506 -0.6273 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E14 mock treatment 139280.0 -6880.0 -0.18 167560.0 21000.0 0.57 0.2715 0.4548 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E15 mock treatment 159200.0 13000.0 0.35 152760.0 6180.0 0.17 0.365 0.9434 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E16 mock treatment 136880.0 -9280.0 -0.25 149560.0 2980.0 0.08 -0.1184 -0.4538 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E17 mock treatment 143200.0 -2960.0 -0.08 154200.0 7620.0 0.21 0.0899 0.407 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E18 mock treatment 132120.0 -14000.0 -0.38 139200.0 -7380.0 -0.2 -0.4068 -0.9564 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E19 mock treatment 143200.0 -2960.0 -0.08 146880.0 301.0 0.01 -0.0502 -0.6311 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E20 mock treatment 162560.0 16400.0 0.44 145800.0 -779.0 -0.02 0.2953 0.6723 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E21 mock treatment 137040.0 -9120.0 -0.24 151560.0 4980.0 0.13 -0.0771 -0.2767 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E22 mock treatment 154720.0 8560.0 0.23 151880.0 5300.0 0.14 0.2634 0.9746 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E23 mock treatment 149840.0 3680.0 0.1 160800.0 14200.0 0.38 0.3419 0.8603 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base E24 mock treatment 145520.0 -638.0 -0.02 143400.0 -3180.0 -0.09 -0.0729 -0.8312 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F01 mock treatment 141080.0 -5080.0 -0.14 148960.0 2380.0 0.06 -0.0505 -0.3358 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F02 mock treatment 143440.0 -2720.0 -0.07 174680.0 28100.0 0.76 0.4865 0.6366 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F03 mock treatment 142880.0 -3280.0 -0.09 155440.0 8860.0 0.24 0.1076 0.4213 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F04 mock treatment 159120.0 13000.0 0.35 172600.0 26000.0 0.7 0.7433 0.9467 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F05 mock treatment 145760.0 -398.0 -0.01 167680.0 21100.0 0.57 0.3964 0.6938 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F06 mock treatment 161040.0 14900.0 0.4 180040.0 33500.0 0.91 0.922 0.9318 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F07 mock treatment 136720.0 -9440.0 -0.25 150960.0 4380.0 0.12 -0.0947 -0.3394 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F08 mock treatment 148960.0 2800.0 0.07 155200.0 8620.0 0.23 0.218 0.8894 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F09 mock treatment 139840.0 -6320.0 -0.17 146560.0 -19.5 0.0 -0.1199 -0.7093 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F10 mock treatment 151640.0 5480.0 0.15 158440.0 11900.0 0.32 0.3307 0.9369 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F11 mock treatment 156880.0 10700.0 0.29 163920.0 17300.0 0.47 0.5347 0.972 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F12 mock treatment 140920.0 -5240.0 -0.14 148920.0 2340.0 0.06 -0.0543 -0.3529 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F13 mock treatment 129720.0 -16400.0 -0.44 160880.0 14300.0 0.39 -0.0372 -0.0634 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F14 mock treatment 147920.0 1760.0 0.05 144400.0 -2180.0 -0.06 -0.0084 -0.1113 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F15 mock treatment 139440.0 -6720.0 -0.18 160760.0 14200.0 0.38 0.1444 0.3406 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F16 mock treatment 145960.0 -198.0 -0.01 163000.0 16400.0 0.44 0.3106 0.6986 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F17 mock treatment 151520.0 5360.0 0.14 154760.0 8180.0 0.22 0.258 0.9779 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F18 mock treatment 144720.0 -1440.0 -0.04 145640.0 -939.0 -0.03 -0.0452 -0.9798 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F19 mock treatment 130800.0 -15400.0 -0.41 165120.0 18500.0 0.5 0.0644 0.0993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F20 mock treatment 139680.0 -6480.0 -0.17 147160.0 581.0 0.02 -0.1114 -0.6403 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F21 mock treatment 128880.0 -17300.0 -0.46 152960.0 6380.0 0.17 -0.2047 -0.4148 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F22 mock treatment 157000.0 10800.0 0.29 163920.0 17300.0 0.47 0.537 0.9732 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F23 mock treatment 141240.0 -4920.0 -0.13 140120.0 -6460.0 -0.17 -0.2167 -0.9902 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base F24 mock treatment 141800.0 -4360.0 -0.12 149960.0 3380.0 0.09 -0.0177 -0.1196 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G01 mock treatment 144800.0 -1360.0 -0.04 145120.0 -1460.0 -0.04 -0.0536 -0.9991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G02 mock treatment 128120.0 -18000.0 -0.48 160480.0 13900.0 0.38 -0.0751 -0.1227 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G03 mock treatment 142240.0 -3920.0 -0.1 140880.0 -5700.0 -0.15 -0.1832 -0.9822 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G04 mock treatment 137560.0 -8600.0 -0.23 142200.0 -4380.0 -0.12 -0.2465 -0.9525 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G05 mock treatment 127720.0 -18400.0 -0.49 146680.0 101.0 0.0 -0.3468 -0.7032 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G06 mock treatment 130200.0 -16000.0 -0.43 144240.0 -2340.0 -0.06 -0.3466 -0.8032 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G07 mock treatment 125200.0 -21000.0 -0.56 128120.0 -18500.0 -0.5 -0.7498 -0.9984 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G08 mock treatment 127160.0 -19000.0 -0.51 136960.0 -9620.0 -0.26 -0.5435 -0.9518 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G09 mock treatment 132080.0 -14100.0 -0.38 135000.0 -11600.0 -0.31 -0.488 -0.9958 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G10 mock treatment 123160.0 -23000.0 -0.62 133440.0 -13100.0 -0.36 -0.6865 -0.9661 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G11 mock treatment 130080.0 -16100.0 -0.43 126400.0 -20200.0 -0.55 -0.6904 -0.993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G12 mock treatment 134840.0 -11300.0 -0.3 142680.0 -3900.0 -0.11 -0.2887 -0.9005 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G13 mock treatment 136360.0 -9800.0 -0.26 138720.0 -7860.0 -0.21 -0.3358 -0.9946 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G14 mock treatment 133560.0 -12600.0 -0.34 130960.0 -15600.0 -0.42 -0.5373 -0.9937 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G15 mock treatment 138480.0 -7680.0 -0.21 130560.0 -16000.0 -0.43 -0.4519 -0.9417 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G16 mock treatment 131760.0 -14400.0 -0.39 143400.0 -3180.0 -0.09 -0.3332 -0.8443 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G17 mock treatment 131760.0 -14400.0 -0.39 142920.0 -3660.0 -0.1 -0.3424 -0.861 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G18 mock treatment 129760.0 -16400.0 -0.44 135880.0 -10700.0 -0.29 -0.515 -0.9797 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G19 mock treatment 131600.0 -14600.0 -0.39 143600.0 -2980.0 -0.08 -0.3324 -0.8358 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G20 mock treatment 131480.0 -14700.0 -0.39 137240.0 -9340.0 -0.25 -0.4564 -0.9773 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G21 mock treatment 150920.0 4760.0 0.13 148000.0 1420.0 0.04 0.1173 0.8813 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G22 mock treatment 127720.0 -18400.0 -0.49 160120.0 13500.0 0.37 -0.0895 -0.1457 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G23 mock treatment 133760.0 -12400.0 -0.33 135400.0 -11200.0 -0.3 -0.4485 -0.999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base G24 mock treatment 125080.0 -21100.0 -0.56 139800.0 -6780.0 -0.18 -0.5285 -0.8913 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H01 mock treatment 130600.0 -15600.0 -0.42 149400.0 2820.0 0.08 -0.2403 -0.5679 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H02 mock treatment 151120.0 4960.0 0.13 156040.0 9460.0 0.26 0.2749 0.9531 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H03 mock treatment 143040.0 -3120.0 -0.08 156360.0 9780.0 0.26 0.1282 0.462 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H04 mock treatment 137560.0 -8600.0 -0.23 174000.0 27400.0 0.74 0.3623 0.4662 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H05 mock treatment 147440.0 1280.0 0.03 150520.0 3940.0 0.11 0.0997 0.8895 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H06 mock treatment 128560.0 -17600.0 -0.47 159920.0 13300.0 0.36 -0.0775 -0.1306 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H07 mock treatment 133560.0 -12600.0 -0.34 142600.0 -3980.0 -0.11 -0.3145 -0.8888 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H08 mock treatment 138400.0 -7760.0 -0.21 147160.0 581.0 0.02 -0.1356 -0.6517 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H09 mock treatment 136240.0 -9920.0 -0.27 137800.0 -8780.0 -0.24 -0.3557 -0.9985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H10 mock treatment 128320.0 -17800.0 -0.48 144080.0 -2500.0 -0.07 -0.3852 -0.7994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H11 mock treatment 120920.0 -25200.0 -0.68 147840.0 1260.0 0.03 -0.4532 -0.6705 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H12 mock treatment 142840.0 -3320.0 -0.09 155800.0 9220.0 0.25 0.1137 0.4293 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H13 mock treatment 132080.0 -14100.0 -0.38 147680.0 1100.0 0.03 -0.2452 -0.6491 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H14 mock treatment 146080.0 -78.4 0.0 129520.0 -17100.0 -0.46 -0.3281 -0.7103 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H15 mock treatment 135480.0 -10700.0 -0.29 127960.0 -18600.0 -0.5 -0.5584 -0.9638 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H16 mock treatment 146960.0 802.0 0.02 148480.0 1900.0 0.05 0.0515 0.9247 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H17 mock treatment 131680.0 -14500.0 -0.39 134680.0 -11900.0 -0.32 -0.5016 -0.9958 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H18 mock treatment 139200.0 -6960.0 -0.19 135440.0 -11100.0 -0.3 -0.3449 -0.9731 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H19 mock treatment 122120.0 -24000.0 -0.64 161520.0 14900.0 0.4 -0.1687 -0.222 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H20 mock treatment 129600.0 -16600.0 -0.44 140080.0 -6500.0 -0.18 -0.4376 -0.9182 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H21 mock treatment 128720.0 -17400.0 -0.47 137440.0 -9140.0 -0.25 -0.5048 -0.956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H22 mock treatment 127360.0 -18800.0 -0.5 141040.0 -5540.0 -0.15 -0.4616 -0.8797 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H23 mock treatment 134160.0 -12000.0 -0.32 143640.0 -2940.0 -0.08 -0.2832 -0.8565 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base H24 mock treatment 128680.0 -17500.0 -0.47 124880.0 -21700.0 -0.59 -0.746 -0.9936 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I01 mock treatment 146600.0 442.0 0.01 153880.0 7300.0 0.2 0.1481 0.748 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I02 mock treatment 142360.0 -3800.0 -0.1 169920.0 23300.0 0.63 0.375 0.5859 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I03 mock treatment 145640.0 -518.0 -0.01 137800.0 -8780.0 -0.24 -0.1779 -0.7471 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I04 mock treatment 141400.0 -4760.0 -0.13 162880.0 16300.0 0.44 0.222 0.4835 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I05 mock treatment 135840.0 -10300.0 -0.28 148400.0 1820.0 0.05 -0.1603 -0.5718 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I06 mock treatment 137480.0 -8680.0 -0.23 165720.0 19100.0 0.52 0.2023 0.3562 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I07 mock treatment 136080.0 -10100.0 -0.27 143720.0 -2860.0 -0.08 -0.2454 -0.8748 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I08 mock treatment 134160.0 -12000.0 -0.32 161160.0 14600.0 0.39 0.0522 0.1026 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I09 mock treatment 128600.0 -17600.0 -0.47 146720.0 141.0 0.0 -0.3294 -0.7014 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I10 mock treatment 146080.0 -78.4 0.0 145000.0 -1580.0 -0.04 -0.0317 -0.7409 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I11 mock treatment 136400.0 -9760.0 -0.26 142040.0 -4540.0 -0.12 -0.2715 -0.941 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I12 mock treatment 160960.0 14800.0 0.4 156160.0 9580.0 0.26 0.4634 0.979 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I13 mock treatment 138960.0 -7200.0 -0.19 142600.0 -3980.0 -0.11 -0.2123 -0.9623 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I14 mock treatment 136320.0 -9840.0 -0.26 134720.0 -11900.0 -0.32 -0.4131 -0.9951 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I15 mock treatment 148480.0 2320.0 0.06 130600.0 -16000.0 -0.43 -0.262 -0.5995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I16 mock treatment 140160.0 -6000.0 -0.16 145760.0 -819.0 -0.02 -0.1291 -0.7973 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I17 mock treatment 131360.0 -14800.0 -0.4 144240.0 -2340.0 -0.06 -0.3247 -0.8099 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I18 mock treatment 136600.0 -9560.0 -0.26 148720.0 2140.0 0.06 -0.1398 -0.5333 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I19 mock treatment 144560.0 -1600.0 -0.04 167400.0 20800.0 0.56 0.3683 0.6516 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I20 mock treatment 132200.0 -14000.0 -0.37 160360.0 13800.0 0.37 -2.0E-4 -4.0E-4 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I21 mock treatment 150080.0 3920.0 0.1 165040.0 18500.0 0.5 0.4276 0.8373 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I22 mock treatment 130640.0 -15500.0 -0.42 169080.0 22500.0 0.61 0.1372 0.1861 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I23 mock treatment 155360.0 9200.0 0.25 139720.0 -6860.0 -0.19 0.0427 0.1386 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base I24 mock treatment 128880.0 -17300.0 -0.46 148800.0 2220.0 0.06 -0.2843 -0.61 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J01 mock treatment 150440.0 4280.0 0.11 143320.0 -3260.0 -0.09 0.0186 0.1286 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J02 mock treatment 135160.0 -11000.0 -0.29 146080.0 -499.0 -0.01 -0.2176 -0.7388 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J03 mock treatment 136520.0 -9640.0 -0.26 139000.0 -7580.0 -0.21 -0.3274 -0.9936 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J04 mock treatment 139520.0 -6640.0 -0.18 169440.0 22900.0 0.62 0.3121 0.4847 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J05 mock treatment 143360.0 -2800.0 -0.07 145320.0 -1260.0 -0.03 -0.077 -0.9366 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J06 mock treatment 144080.0 -2080.0 -0.06 145800.0 -779.0 -0.02 -0.0542 -0.912 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J07 mock treatment 154720.0 8560.0 0.23 134840.0 -11700.0 -0.32 -0.0628 -0.1603 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J08 mock treatment 139880.0 -6280.0 -0.17 143480.0 -3100.0 -0.08 -0.1781 -0.9486 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J09 mock treatment 143040.0 -3120.0 -0.08 142000.0 -4580.0 -0.12 -0.1466 -0.9814 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J10 mock treatment 140600.0 -5560.0 -0.15 141720.0 -4860.0 -0.13 -0.1982 -0.9981 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J11 mock treatment 132320.0 -13800.0 -0.37 156600.0 10000.0 0.27 -0.0699 -0.1524 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J12 mock treatment 129680.0 -16500.0 -0.44 148920.0 2340.0 0.06 -0.2669 -0.5993 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J13 mock treatment 152560.0 6400.0 0.17 143080.0 -3500.0 -0.09 0.0541 0.2764 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J14 mock treatment 138520.0 -7640.0 -0.2 140760.0 -5820.0 -0.16 -0.2559 -0.9918 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J15 mock treatment 129960.0 -16200.0 -0.43 133760.0 -12800.0 -0.35 -0.5518 -0.9939 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J16 mock treatment 130440.0 -15700.0 -0.42 128840.0 -17700.0 -0.48 -0.6369 -0.9978 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J17 mock treatment 147480.0 1320.0 0.04 139360.0 -7220.0 -0.2 -0.1132 -0.57 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J18 mock treatment 129600.0 -16600.0 -0.44 118480.0 -28100.0 -0.76 -0.8511 -0.9669 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J19 mock treatment 138000.0 -8160.0 -0.22 143800.0 -2780.0 -0.08 -0.2075 -0.899 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J20 mock treatment 133040.0 -13100.0 -0.35 137400.0 -9180.0 -0.25 -0.4238 -0.9857 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J21 mock treatment 169280.0 23100.0 0.62 142800.0 -3780.0 -0.1 0.365 0.5822 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J22 mock treatment 125120.0 -21000.0 -0.56 137440.0 -9140.0 -0.25 -0.5729 -0.9319 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J23 mock treatment 141680.0 -4480.0 -0.12 130040.0 -16500.0 -0.45 -0.4013 -0.8658 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base J24 mock treatment 127280.0 -18900.0 -0.5 159560.0 13000.0 0.35 -0.1086 -0.1765 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K01 mock treatment 155720.0 9560.0 0.26 137720.0 -8860.0 -0.24 0.0113 0.0321 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K02 mock treatment 130800.0 -15400.0 -0.41 148080.0 1500.0 0.04 -0.2618 -0.6341 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K03 mock treatment 143200.0 -2960.0 -0.08 144640.0 -1940.0 -0.05 -0.0931 -0.9801 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K04 mock treatment 141000.0 -5160.0 -0.14 148000.0 1420.0 0.04 -0.0704 -0.4913 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K05 mock treatment 126720.0 -19400.0 -0.52 147080.0 501.0 0.01 -0.3581 -0.6884 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K06 mock treatment 151480.0 5320.0 0.14 176080.0 29500.0 0.8 0.6654 0.8202 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K07 mock treatment 137680.0 -8480.0 -0.23 152560.0 5980.0 0.16 -0.0459 -0.1646 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K08 mock treatment 139640.0 -6520.0 -0.17 150480.0 3900.0 0.11 -0.0486 -0.2385 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K09 mock treatment 143320.0 -2840.0 -0.08 131600.0 -15000.0 -0.41 -0.3404 -0.8252 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K10 mock treatment 144080.0 -2080.0 -0.06 130080.0 -16500.0 -0.45 -0.3552 -0.789 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K11 mock treatment 134720.0 -11400.0 -0.31 142840.0 -3740.0 -0.1 -0.2879 -0.8934 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K12 mock treatment 145640.0 -518.0 -0.01 136120.0 -10500.0 -0.28 -0.21 -0.7408 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K13 mock treatment 124520.0 -21600.0 -0.58 146120.0 -459.0 -0.01 -0.4181 -0.7221 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K14 mock treatment 143720.0 -2440.0 -0.07 135080.0 -11500.0 -0.31 -0.2663 -0.8371 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K15 mock treatment 138000.0 -8160.0 -0.22 144640.0 -1940.0 -0.05 -0.1914 -0.8529 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K16 mock treatment 154880.0 8720.0 0.23 132400.0 -14200.0 -0.38 -0.1065 -0.237 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K17 mock treatment 121720.0 -24400.0 -0.65 116120.0 -30500.0 -0.82 -1.0453 -0.9934 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K18 mock treatment 130960.0 -15200.0 -0.41 135400.0 -11200.0 -0.3 -0.5015 -0.9894 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K19 mock treatment 141880.0 -4280.0 -0.11 127200.0 -19400.0 -0.52 -0.4519 -0.8416 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K20 mock treatment 122160.0 -24000.0 -0.64 142400.0 -4180.0 -0.11 -0.5339 -0.8191 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K21 mock treatment 127840.0 -18300.0 -0.49 137920.0 -8660.0 -0.23 -0.5122 -0.943 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K22 mock treatment 132720.0 -13400.0 -0.36 164200.0 17600.0 0.48 0.0831 0.1392 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K23 mock treatment 131360.0 -14800.0 -0.4 153360.0 6780.0 0.18 -0.1501 -0.344 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base K24 mock treatment 136080.0 -10100.0 -0.27 143080.0 -3500.0 -0.09 -0.2576 -0.9016 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L01 mock treatment 164600.0 18400.0 0.49 133480.0 -13100.0 -0.35 0.098 0.1614 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L02 mock treatment 140760.0 -5400.0 -0.14 151200.0 4620.0 0.13 -0.0137 -0.0715 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L03 mock treatment 136600.0 -9560.0 -0.26 135800.0 -10800.0 -0.29 -0.3871 -0.9978 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L04 mock treatment 136440.0 -9720.0 -0.26 131960.0 -14600.0 -0.4 -0.4637 -0.9792 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L05 mock treatment 133200.0 -13000.0 -0.35 137080.0 -9500.0 -0.26 -0.4269 -0.9892 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L06 mock treatment 157440.0 11300.0 0.3 139960.0 -6620.0 -0.18 0.0867 0.2469 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L07 mock treatment 131160.0 -15000.0 -0.4 130040.0 -16500.0 -0.45 -0.6003 -0.9985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L08 mock treatment 143240.0 -2920.0 -0.08 127320.0 -19300.0 -0.52 -0.4239 -0.804 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L09 mock treatment 134480.0 -11700.0 -0.31 134280.0 -12300.0 -0.33 -0.4563 -0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L10 mock treatment 146360.0 202.0 0.01 135120.0 -11500.0 -0.31 -0.2156 -0.6947 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L11 mock treatment 136000.0 -10200.0 -0.27 146080.0 -499.0 -0.01 -0.2017 -0.7414 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L12 mock treatment 138360.0 -7800.0 -0.21 128400.0 -18200.0 -0.49 -0.4955 -0.927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L13 mock treatment 124840.0 -21300.0 -0.57 129960.0 -16600.0 -0.45 -0.7214 -0.9931 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L14 mock treatment 124120.0 -22000.0 -0.59 136200.0 -10400.0 -0.28 -0.6155 -0.9426 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L15 mock treatment 132840.0 -13300.0 -0.36 132960.0 -13600.0 -0.37 -0.5126 -0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L16 mock treatment 137680.0 -8480.0 -0.23 119640.0 -26900.0 -0.73 -0.6761 -0.8852 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L17 mock treatment 144640.0 -1520.0 -0.04 132680.0 -13900.0 -0.38 -0.2948 -0.7789 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L18 mock treatment 131760.0 -14400.0 -0.39 127920.0 -18700.0 -0.51 -0.6295 -0.991 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L19 mock treatment 137480.0 -8680.0 -0.23 131720.0 -14900.0 -0.4 -0.4486 -0.9659 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L20 mock treatment 143480.0 -2680.0 -0.07 140120.0 -6460.0 -0.17 -0.1743 -0.9224 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L21 mock treatment 120840.0 -25300.0 -0.68 120600.0 -26000.0 -0.7 -0.9762 -0.9998 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L22 mock treatment 121400.0 -24800.0 -0.66 130040.0 -16500.0 -0.45 -0.7849 -0.9818 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L23 mock treatment 128600.0 -17600.0 -0.47 148400.0 1820.0 0.05 -0.2973 -0.6294 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base L24 mock treatment 123480.0 -22700.0 -0.61 118560.0 -28000.0 -0.76 -0.9653 -0.9939 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M01 mock treatment 169880.0 23700.0 0.63 127400.0 -19200.0 -0.52 0.0815 0.0994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M02 mock treatment 124280.0 -21900.0 -0.59 148000.0 1420.0 0.04 -0.3866 -0.6592 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M03 mock treatment 131840.0 -14300.0 -0.38 132080.0 -14500.0 -0.39 -0.5484 -0.9999 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M04 mock treatment 157760.0 11600.0 0.31 154520.0 7940.0 0.21 0.3714 0.9839 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M05 mock treatment 151520.0 5360.0 0.14 121240.0 -25300.0 -0.69 -0.3837 -0.5474 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M06 mock treatment 142200.0 -3960.0 -0.11 145440.0 -1140.0 -0.03 -0.0967 -0.8767 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M07 mock treatment 124440.0 -21700.0 -0.58 139000.0 -7580.0 -0.21 -0.5559 -0.9022 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M08 mock treatment 138480.0 -7680.0 -0.21 138480.0 -8100.0 -0.22 -0.3003 -0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M09 mock treatment 139440.0 -6720.0 -0.18 137440.0 -9140.0 -0.25 -0.302 -0.9877 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M10 mock treatment 139360.0 -6800.0 -0.18 137040.0 -9540.0 -0.26 -0.3112 -0.9853 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M11 mock treatment 134200.0 -12000.0 -0.32 125400.0 -21200.0 -0.57 -0.6316 -0.962 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M12 mock treatment 139960.0 -6200.0 -0.17 139840.0 -6740.0 -0.18 -0.2463 -0.9989 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M13 mock treatment 147440.0 1280.0 0.03 134040.0 -12500.0 -0.34 -0.2158 -0.6325 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M14 mock treatment 144600.0 -1560.0 -0.04 131560.0 -15000.0 -0.41 -0.317 -0.7755 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M15 mock treatment 183400.0 37200.0 1.0 126080.0 -20500.0 -0.55 0.312 0.2736 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M16 mock treatment 143600.0 -2560.0 -0.07 134880.0 -11700.0 -0.32 -0.2724 -0.8405 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M17 mock treatment 132080.0 -14100.0 -0.38 138600.0 -7980.0 -0.22 -0.419 -0.9652 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M18 mock treatment 135600.0 -10600.0 -0.28 129120.0 -17500.0 -0.47 -0.5339 -0.9697 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M19 mock treatment 136960.0 -9200.0 -0.25 135600.0 -11000.0 -0.3 -0.3842 -0.9956 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M20 mock treatment 142280.0 -3880.0 -0.1 133080.0 -13500.0 -0.37 -0.3318 -0.8733 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M21 mock treatment 149440.0 3280.0 0.09 127880.0 -18700.0 -0.51 -0.2959 -0.5759 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M22 mock treatment 123200.0 -23000.0 -0.61 144840.0 -1740.0 -0.05 -0.4675 -0.7591 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M23 mock treatment 154440.0 8280.0 0.22 134760.0 -11800.0 -0.32 -0.0696 -0.1789 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base M24 mock treatment 140960.0 -5200.0 -0.14 143480.0 -3100.0 -0.08 -0.1577 -0.9708 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N01 mock treatment 182760.0 36600.0 0.98 144720.0 -1860.0 -0.05 0.6567 0.6699 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N02 mock treatment 145320.0 -838.0 -0.02 150240.0 3660.0 0.1 0.0542 0.5336 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N03 mock treatment 135840.0 -10300.0 -0.28 152320.0 5740.0 0.16 -0.0853 -0.2692 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N04 mock treatment 143360.0 -2800.0 -0.07 157640.0 11100.0 0.3 0.1588 0.5145 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N05 mock treatment 149120.0 2960.0 0.08 159160.0 12600.0 0.34 0.2968 0.8489 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N06 mock treatment 129600.0 -16600.0 -0.44 136720.0 -9860.0 -0.27 -0.5019 -0.9706 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N07 mock treatment 123560.0 -22600.0 -0.6 129120.0 -17500.0 -0.47 -0.7617 -0.9926 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N08 mock treatment 144560.0 -1600.0 -0.04 129080.0 -17500.0 -0.47 -0.3652 -0.7678 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N09 mock treatment 163720.0 17600.0 0.47 124280.0 -22300.0 -0.6 -0.0947 -0.1238 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N10 mock treatment 156360.0 10200.0 0.27 133440.0 -13100.0 -0.36 -0.0586 -0.1307 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N11 mock treatment 140000.0 -6160.0 -0.16 134320.0 -12300.0 -0.33 -0.3512 -0.9477 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N12 mock treatment 145040.0 -1120.0 -0.03 137800.0 -8780.0 -0.24 -0.1892 -0.7899 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N13 mock treatment 150240.0 4080.0 0.11 124840.0 -21700.0 -0.59 -0.339 -0.5663 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N14 mock treatment 160960.0 14800.0 0.4 142120.0 -4460.0 -0.12 0.1946 0.4701 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N15 mock treatment 135160.0 -11000.0 -0.29 127800.0 -18800.0 -0.51 -0.5675 -0.9662 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N16 mock treatment 162920.0 16800.0 0.45 123240.0 -23300.0 -0.63 -0.1298 -0.1675 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N17 mock treatment 143640.0 -2520.0 -0.07 137960.0 -8620.0 -0.23 -0.2126 -0.8755 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N18 mock treatment 140080.0 -6080.0 -0.16 130440.0 -16100.0 -0.44 -0.4239 -0.9093 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N19 mock treatment 132320.0 -13800.0 -0.37 126640.0 -19900.0 -0.54 -0.6434 -0.9831 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N20 mock treatment 132600.0 -13600.0 -0.36 154480.0 7900.0 0.21 -0.1052 -0.2499 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N21 mock treatment 129520.0 -16600.0 -0.45 137080.0 -9500.0 -0.26 -0.4966 -0.966 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N22 mock treatment 123560.0 -22600.0 -0.6 138080.0 -8500.0 -0.23 -0.5901 -0.9124 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N23 mock treatment 132240.0 -13900.0 -0.37 132880.0 -13700.0 -0.37 -0.5255 -1.0 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base N24 mock treatment 121840.0 -24300.0 -0.65 147080.0 501.0 0.01 -0.4504 -0.6922 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O01 mock treatment 174960.0 28800.0 0.77 149600.0 3020.0 0.08 0.6026 0.7778 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O02 mock treatment 124280.0 -21900.0 -0.59 131680.0 -14900.0 -0.4 -0.699 -0.9835 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O03 mock treatment 120840.0 -25300.0 -0.68 128840.0 -17700.0 -0.48 -0.8185 -0.9858 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O04 mock treatment 125320.0 -20800.0 -0.56 149680.0 3100.0 0.08 -0.3348 -0.5939 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O05 mock treatment 151880.0 5720.0 0.15 123160.0 -23400.0 -0.63 -0.3401 -0.5214 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O06 mock treatment 137600.0 -8560.0 -0.23 146000.0 -579.0 -0.02 -0.173 -0.7538 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O07 mock treatment 141880.0 -4280.0 -0.11 117680.0 -28900.0 -0.78 -0.6342 -0.802 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O08 mock treatment 147640.0 1480.0 0.04 146320.0 -259.0 -0.01 0.0231 0.5728 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O09 mock treatment 139800.0 -6360.0 -0.17 112920.0 -33700.0 -0.91 -0.7646 -0.8248 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O10 mock treatment 126040.0 -20100.0 -0.54 142800.0 -3780.0 -0.1 -0.4529 -0.8267 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O11 mock treatment 137760.0 -8400.0 -0.22 115080.0 -31500.0 -0.85 -0.7618 -0.8639 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O12 mock treatment 123760.0 -22400.0 -0.6 119080.0 -27500.0 -0.74 -0.9501 -0.9942 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O13 mock treatment 127880.0 -18300.0 -0.49 113280.0 -33300.0 -0.9 -0.9832 -0.9587 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O14 mock treatment 126320.0 -19800.0 -0.53 156040.0 9460.0 0.26 -0.1941 -0.3295 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O15 mock treatment 121400.0 -24800.0 -0.66 137680.0 -8900.0 -0.24 -0.6387 -0.9062 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O16 mock treatment 132880.0 -13300.0 -0.36 115080.0 -31500.0 -0.85 -0.8542 -0.9246 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O17 mock treatment 138480.0 -7680.0 -0.21 124920.0 -21700.0 -0.59 -0.5599 -0.9011 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O18 mock treatment 139400.0 -6760.0 -0.18 117080.0 -29500.0 -0.8 -0.6925 -0.8458 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O19 mock treatment 133600.0 -12600.0 -0.34 139320.0 -7260.0 -0.2 -0.3765 -0.9674 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O20 mock treatment 128760.0 -17400.0 -0.47 157360.0 10800.0 0.29 -0.1227 -0.2234 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O21 mock treatment 130720.0 -15400.0 -0.41 134160.0 -12400.0 -0.34 -0.5298 -0.9948 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O22 mock treatment 121480.0 -24700.0 -0.66 129720.0 -16900.0 -0.46 -0.7895 -0.9838 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O23 mock treatment 125880.0 -20300.0 -0.54 134240.0 -12300.0 -0.33 -0.6198 -0.9729 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base O24 mock treatment 144720.0 -1440.0 -0.04 131080.0 -15500.0 -0.42 -0.3239 -0.7687 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P01 mock treatment 174640.0 28500.0 0.76 151200.0 4620.0 0.13 0.6272 0.8123 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P02 mock treatment 146880.0 722.0 0.02 132040.0 -14500.0 -0.39 -0.2647 -0.6716 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P03 mock treatment 129720.0 -16400.0 -0.44 120360.0 -26200.0 -0.71 -0.8128 -0.9735 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P04 mock treatment 130160.0 -16000.0 -0.43 128920.0 -17700.0 -0.48 -0.6407 -0.9985 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P05 mock treatment 129000.0 -17200.0 -0.46 128480.0 -18100.0 -0.49 -0.671 -0.9995 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P06 mock treatment 139400.0 -6760.0 -0.18 132920.0 -13700.0 -0.37 -0.3893 -0.9458 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P07 mock treatment 120120.0 -26000.0 -0.7 129880.0 -16700.0 -0.45 -0.8122 -0.9781 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P08 mock treatment 135720.0 -10400.0 -0.28 116760.0 -29800.0 -0.81 -0.7683 -0.8994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P09 mock treatment 133720.0 -12400.0 -0.33 114760.0 -31800.0 -0.86 -0.8444 -0.9144 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P10 mock treatment 137000.0 -9160.0 -0.24 124040.0 -22500.0 -0.61 -0.6047 -0.9196 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P11 mock treatment 133200.0 -13000.0 -0.35 129440.0 -17100.0 -0.46 -0.5732 -0.9897 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P12 mock treatment 134560.0 -11600.0 -0.31 125040.0 -21500.0 -0.58 -0.6317 -0.9564 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P13 mock treatment 114880.0 -31300.0 -0.84 122360.0 -24200.0 -0.66 -1.0552 -0.9927 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P14 mock treatment 121040.0 -25100.0 -0.67 131520.0 -15100.0 -0.41 -0.7634 -0.9713 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P15 mock treatment 117280.0 -28900.0 -0.77 110120.0 -36500.0 -0.99 -1.2442 -0.9926 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P16 mock treatment 128800.0 -17400.0 -0.46 111560.0 -35000.0 -0.95 -0.9987 -0.946 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P17 mock treatment 119240.0 -26900.0 -0.72 118080.0 -28500.0 -0.77 -1.0547 -0.9994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P18 mock treatment 131680.0 -14500.0 -0.39 117080.0 -29500.0 -0.8 -0.8386 -0.9448 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P19 mock treatment 120440.0 -25700.0 -0.69 133880.0 -12700.0 -0.34 -0.7296 -0.9486 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P20 mock treatment 114320.0 -31800.0 -0.85 121360.0 -25200.0 -0.68 -1.085 -0.994 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P21 mock treatment 117480.0 -28700.0 -0.77 129280.0 -17300.0 -0.47 -0.8736 -0.972 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P22 mock treatment 119240.0 -26900.0 -0.72 121280.0 -25300.0 -0.68 -0.9935 -0.9997 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P23 mock treatment 128440.0 -17700.0 -0.47 131960.0 -14600.0 -0.4 -0.615 -0.996 1108.0004 CellTiterGlo(1108.0004) e-CadherinSyntheticLethalAssay 1108.0004.Base P24 mock treatment 144480.0 -1680.0 -0.04 138240.0 -8340.0 -0.23 -0.1914 -0.8314