ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A01 mock treatment 110080.0 -63200.0 -1.96 171440.0 16100.0 0.42 -1.089 -0.5439 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A02 mock treatment 208760.0 35500.0 1.1 215200.0 59800.0 1.55 1.877 0.9856 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A03 compound treatment 52880.0 -120000.0 -3.73 40920.0 -114000.0 -2.97 -4.7402 -0.9937 3076292 SMP2_000001 C[C@H](CCCC(C)(C)O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A04 compound treatment 217320.0 44100.0 1.36 231720.0 76400.0 1.98 2.3681 0.9833 170 SMP2_000002 CCCCCCCC[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A05 compound treatment 213320.0 40100.0 1.24 198560.0 43200.0 1.12 1.6712 0.9987 3076293 SMP2_000003 CN(C)CC/C=C/1\c2ccccc2CC(O)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A06 compound treatment 51600.0 -122000.0 -3.77 18360.0 -137000.0 -3.56 -5.1827 -0.9996 2153 SMP2_000004 C[C@@H]1[C@@H](OC(=O)/C=C/C=C/c2ccccc2)[C@@]3(OC4(O[C@@H]3[C@@H]5[C@@H]6O[C@]6(CO)[C@@H](O)[C@@]7(O)[C@@H](C=C(C)C7=O)[C@@]15O4)c8ccccc8)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A07 compound treatment 171080.0 -2190.0 -0.07 74920.0 -80400.0 -2.09 -1.5258 -0.7297 3471112 SMP2_000005 CCOC(=O)CCC(=O)OC1C(CC(C)OC1OC2C(C)C(OC3CC(C)(OC)C(O)C(C)O3)C(C)C(=O)OC(CC)C(C)(O)C(O)C(C)C(=O)C(C)CC2(C)O)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A08 compound treatment 181240.0 7970.0 0.25 177720.0 22400.0 0.58 0.5855 0.9274 2199 SMP2_000006 CC(C(C)c1ccc(O)cn1)C(N)C(=O)NC([C@H]2O[C@H]([C@@H](O)[C@H]2O)N3C=CC(=O)CC3=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A09 compound treatment 184160.0 10900.0 0.34 144760.0 -10600.0 -0.28 0.0439 0.1008 698 SMP2_000007 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A10 compound treatment 13640.0 -160000.0 -4.95 9680.0 -146000.0 -3.79 -6.1739 -0.9913 3199281 SMP2_000008 CC(=C[C@@H](O)C1=C[C@@H](O)[C@@H]2O[C@@H]2C1=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A11 compound treatment 177080.0 3810.0 0.12 201960.0 46600.0 1.21 0.9397 0.7724 1001979 SMP2_000009 NCCC[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A12 compound treatment 119840.0 -53400.0 -1.66 85520.0 -69800.0 -1.81 -2.4537 -0.9989 3199282 SMP2_000010 C[C@@H]1[C@@H](OC(=O)C)[C@]2(OC(=O)C)[C@H]([C@@H]3C=C(CO)C[C@]4(O)[C@@H](C=C(C)C4=O)[C@]13O)C2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A13 compound treatment 172680.0 -588.0 -0.02 199720.0 44400.0 1.15 0.8021 0.6958 1497 SMP2_000011 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)C2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A14 compound treatment 162440.0 -10800.0 -0.34 225400.0 70000.0 1.82 1.0496 0.5672 1000212 SMP2_000012 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A15 compound treatment 187560.0 14300.0 0.44 213400.0 58000.0 1.51 1.3795 0.8777 3199283 SMP2_000013 COC1/C=C\OC2(C)Oc3c(C2=O)c4c(O)cc(NC(=O)\C(=C/C=C\C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)\C)c(O)c4c(O)c3C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A16 compound treatment 21160.0 -152000.0 -4.71 17880.0 -137000.0 -3.57 -5.8584 -0.9907 2267 SMP2_000014 CO[C@H]1[C@H](O)C(O)[C@@H](OC1CO)n2c3c(Cl)cccc3c4c5C(=O)NC(=O)c5c6c7cccc(Cl)c7[nH]c6c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A17 compound treatment 205760.0 32500.0 1.01 164520.0 9160.0 0.24 0.8802 0.8508 706 SMP2_000015 Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A18 compound treatment 13960.0 -159000.0 -4.94 14480.0 -141000.0 -3.66 -6.0787 -0.9892 1098997 SMP2_000016 CCC1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A19 compound treatment 147200.0 -26100.0 -0.81 102480.0 -52900.0 -1.37 -1.5427 -0.9679 1001956 SMP2_000017 CC(C)C1N(C)c2cccc3[nH]cc(CC(CO)NC1=O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A20 compound treatment 240720.0 67500.0 2.09 214960.0 59600.0 1.55 2.5729 0.9891 1912779 SMP2_000018 CC(NC(=O)c1ccccc1/N=C/c2c(O)ccc3ccccc23)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A21 compound treatment 147200.0 -26100.0 -0.81 123040.0 -32300.0 -0.84 -1.1649 -0.9998 230 SMP2_000019 CCCCCC(=O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A22 compound treatment 8640.0 -165000.0 -5.1 7920.0 -147000.0 -3.83 -6.3157 -0.99 464 SMP2_000020 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A23 compound treatment 282160.0 109000.0 3.37 286160.0 131000.0 3.4 4.7889 1.0 548 SMP2_000021 N[C@H]1C[C@H]([C@H](O)[C@@H]1O)n2cc(I)c3c(N)ncnc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 A24 compound treatment 103320.0 -69900.0 -2.17 189640.0 34300.0 0.89 -0.9027 -0.3852 3199284 SMP2_000022 C/C(=C/CNc1ncnc2[nH]cnc12)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B01 mock treatment 229880.0 56600.0 1.75 224240.0 68900.0 1.79 2.5059 0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B02 mock treatment 215280.0 42000.0 1.3 233520.0 78200.0 2.03 2.3565 0.9769 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B03 compound treatment 223960.0 50700.0 1.57 214680.0 59300.0 1.54 2.2005 1.0 1001866 SMP2_000023 NC(CCCNC(=N)N)C(=O)CC(Cc1ccccc1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B04 compound treatment 12720.0 -161000.0 -4.97 11480.0 -144000.0 -3.74 -6.1609 -0.9901 3076299 SMP2_000024 C[C@@H]1CCOC(=O)/C=C\C=C/C(=O)O[C@@H]2C[C@@H]3OC4C=C(C)CCC4(COC(=O)[C@H]1O)[C@]2(C)[C@@]53CO5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B05 compound treatment 182320.0 9050.0 0.28 185800.0 30400.0 0.79 0.7576 0.9028 3199377 SMP2_000025 CO[C@@H]1C[C@H](C)O[C@@H](CC[C@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)/C(=C/C[C@H](O)C[C@H]3O[C@@H](CC=C3)C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@H](C)[C@H](OC(=O)/C(=C/C[C@H](O)C[C@H]4O[C@@H](CC=C4)C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@@H]2C)/C)[C@@H](C)[C@@H](O)[C@@H](C)CC[C@@H]5C[C@@H](C[C@H](C)O5)OC)/C)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B06 compound treatment 115240.0 -58000.0 -1.8 68840.0 -86500.0 -2.25 -2.8609 -0.9939 3076300 SMP2_000026 CC1(C)C(O)C2(C)CCC1C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B07 compound treatment 162000.0 -11300.0 -0.35 172120.0 16800.0 0.44 0.0611 0.1094 3199378 SMP2_000027 CC(CO)C1CC(O)C2(C)OC3CC4OC5CC6(C)OC7CCC8OC9CC%10(C)OC%11C(CC%10OC9CC(C)C8OC7CC6OC5(C)CC=CC4OC3CC2O1)OC(=O)C=C%11C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B08 compound treatment 184040.0 10800.0 0.33 140640.0 -14700.0 -0.38 -0.0344 -0.0678 3076301 SMP2_000028 Cn1cc(C[C@@H](N)C(=O)O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B09 compound treatment 11240.0 -162000.0 -5.02 9520.0 -146000.0 -3.79 -6.2294 -0.9904 28 SMP2_000029 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B10 compound treatment 14680.0 -159000.0 -4.91 9000.0 -146000.0 -3.8 -6.1636 -0.992 3199379 SMP2_000030 CC(C)CC(CO)NC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)(C)NC(=O)C(CC(C)C)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B11 compound treatment 141960.0 -31300.0 -0.97 219360.0 64000.0 1.66 0.4899 0.2545 2006 SMP2_000031 O[C@H]1C2OC2[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B12 compound treatment 121440.0 -51800.0 -1.61 91320.0 -64000.0 -1.66 -2.3121 -0.9998 3076303 SMP2_000032 CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B13 compound treatment 21400.0 -152000.0 -4.71 12120.0 -143000.0 -3.72 -5.959 -0.9933 3076304 SMP2_000033 CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C/2\C(=O)Nc3ccc(Cl)cc23)c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B14 compound treatment 220040.0 46800.0 1.45 226960.0 71600.0 1.86 2.3402 0.9924 1000114 SMP2_000034 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B15 compound treatment 268200.0 94900.0 2.94 203040.0 47700.0 1.24 2.9559 0.9261 277 SMP2_000035 OC[C@H]1O[C@H]([C@H](O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B16 compound treatment 183280.0 10000.0 0.31 188640.0 33300.0 0.86 0.8308 0.9043 3076306 SMP2_000036 CC(=O)c1ccc(cc1O)N2CCOCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B17 compound treatment 33600.0 -140000.0 -4.33 10520.0 -145000.0 -3.76 -5.7211 -0.9976 2095622 SMP2_000037 CC(=CCC/C(=C/CC/C(=C/Cc1c(O)c2ccccc2oc1=O)/C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B18 compound treatment 183880.0 10600.0 0.33 221760.0 66400.0 1.73 1.4525 0.827 1670 SMP2_000038 Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B19 compound treatment 23120.0 -150000.0 -4.65 10200.0 -145000.0 -3.77 -5.9566 -0.9946 2090 SMP2_000039 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B20 compound treatment 18600.0 -155000.0 -4.79 6880.0 -148000.0 -3.86 -6.1166 -0.9942 1096696 SMP2_000040 Oc1ccc(cc1CC=C)c2cc(CC=C)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B21 compound treatment 194840.0 21600.0 0.67 169800.0 14400.0 0.38 0.7379 0.9627 3199380 SMP2_000041 NC1=NC(=O)/C(=C\2/CCNC(=O)c3[nH]c(Br)cc23)/N1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B22 compound treatment 134640.0 -38600.0 -1.2 186280.0 30900.0 0.8 -0.2782 -0.193 2137 SMP2_000042 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B23 compound treatment 64600.0 -109000.0 -3.37 57200.0 -98200.0 -2.55 -4.1843 -0.9906 3104545 SMP2_000043 CC1CC(C)/C=C(/C)\CC(C)C(=O)NC(C)C(=O)N(C)C(Cc2c(Br)[nH]c3ccccc23)C(=O)NC(CC(=O)O1)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 B24 compound treatment 6480.0 -167000.0 -5.17 6720.0 -149000.0 -3.86 -6.3851 -0.9897 907437 SMP2_000044 CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@@H](N)CCCCN 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C01 mock treatment 212600.0 39300.0 1.22 215400.0 60000.0 1.56 1.9648 0.9925 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C02 mock treatment 216280.0 43000.0 1.33 189760.0 34400.0 0.89 1.5744 0.9811 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C03 compound treatment 93400.0 -79900.0 -2.47 66280.0 -89100.0 -2.31 -3.3865 -0.9994 907417 SMP2_000045 COc1cc2[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@@H]3CCc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C04 compound treatment 170240.0 -3030.0 -0.09 150160.0 -5200.0 -0.14 -0.1619 -0.9842 180 SMP2_000046 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(N)C(=O)NCC(=O)O)[C@@H](O)CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C05 compound treatment 8880.0 -164000.0 -5.09 8160.0 -147000.0 -3.82 -6.3061 -0.99 3199382 SMP2_000047 C[C@@H]1CCC2[C@H](C[C@]3(C)C(=CCC4[C@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C06 compound treatment 9440.0 -164000.0 -5.08 7480.0 -148000.0 -3.84 -6.3063 -0.9906 3104900 SMP2_000048 C/C(=C\CCC1C=CC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C07 compound treatment 32760.0 -141000.0 -4.35 19160.0 -136000.0 -3.54 -5.5808 -0.9947 907313 SMP2_000049 Oc1c(I)cc2c(Oc3c(I)c(O)c(I)cc3C42OC(=O)c5ccccc54)c1I 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C08 compound treatment 171000.0 -2270.0 -0.07 171280.0 15900.0 0.41 0.2428 0.5787 3076308 SMP2_000050 CCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C09 compound treatment 175440.0 2170.0 0.07 180840.0 25500.0 0.66 0.5157 0.775 1002910 SMP2_000051 OC(C(O)C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C10 compound treatment 152640.0 -20600.0 -0.64 176360.0 21000.0 0.55 -0.0661 -0.0787 453 SMP2_000052 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C11 compound treatment 38760.0 -135000.0 -4.17 37200.0 -118000.0 -3.07 -5.1179 -0.9887 3199383 SMP2_000053 C[C@@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC[C@@]32C)[C@]45O[C@@H]5C[C@@H](C14)c6ccc(=O)oc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C12 compound treatment 190280.0 17000.0 0.53 218560.0 63200.0 1.64 1.5339 0.8894 3199384 SMP2_000054 CC[C@H]1OC(=O)C[C@@H](O)C[C@@H](OC[C@]2(C)OC(C)[C@@H](O[C@@]3(C)C[C@@](C)(O)[C@@H](O)C(C)O3)[C@H](C2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C\C(=C/C1CO[C@@H]4OC(C)[C@@H](O)[C@H](OC)C4OC)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C13 compound treatment 174880.0 1610.0 0.05 153960.0 -1400.0 -0.04 0.0096 0.1556 3076309 SMP2_000055 C[C@]12CC[C@H](C3CCC(C)(C)OC3)[C@@]2(C)[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5[C@@H](O)C[C@]41C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C14 compound treatment 181400.0 8130.0 0.25 149400.0 -5960.0 -0.15 0.0687 0.2322 222 SMP2_000056 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C15 compound treatment 105480.0 -67800.0 -2.1 13000.0 -142000.0 -3.7 -4.1007 -0.964 3076310 SMP2_000057 CC1(C)CC[C@H](F)[C@@]2(CO[C@@]3(O)[C@H](O)[C@H]12)[C@@H]4CC[C@@H]5[C@@H](O)[C@@]43C(=O)C5=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C16 compound treatment 172400.0 -868.0 -0.03 200120.0 44800.0 1.16 0.8034 0.6906 3199385 SMP2_000058 OC[C@@H]1C[C@H](N[C@@H]2C=C(CO)[C@@H](O)[C@H](O)[C@H]2O)C(O)C(O)[C@@H]1O[C@@H]3OC(CO)[C@@H](O)[C@H](O)[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C17 compound treatment 216120.0 42900.0 1.33 153800.0 -1560.0 -0.04 0.9102 0.6852 1448 SMP2_000059 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C18 compound treatment 163360.0 -9910.0 -0.31 53440.0 -102000.0 -2.65 -2.0896 -0.7838 31 SMP2_000060 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C19 compound treatment 11200.0 -162000.0 -5.02 8000.0 -147000.0 -3.83 -6.2582 -0.991 95 SMP2_000061 CCCCCC(O)/C=C/C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C20 compound treatment 7600.0 -166000.0 -5.13 6760.0 -149000.0 -3.86 -6.3598 -0.9901 2065223 SMP2_000062 CN(C)c1ccc(cc1)C(O)(c2ccccc2)c3ccc(cc3)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C21 compound treatment 16760.0 -157000.0 -4.85 12000.0 -143000.0 -3.72 -6.0629 -0.9915 3199386 SMP2_000063 CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)/C(=C\C=C/[C@H](O)[C@@H](OC(=O)N)/C(=C\[C@H](C)[C@H]1O)/C)/C)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C22 compound treatment 208160.0 34900.0 1.08 217440.0 62100.0 1.61 1.905 0.9811 2041 SMP2_000064 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C23 compound treatment 259440.0 86200.0 2.67 205480.0 50100.0 1.3 2.8088 0.9455 3076311 SMP2_000065 COc1cc2ccnc3cc[nH]c(c1OC)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 C24 compound treatment 129880.0 -43400.0 -1.34 168840.0 13500.0 0.35 -0.7029 -0.506 907566 SMP2_000066 C/C(=C\CNc1ncnc2n(cnc12)C3OC(CO)[C@@H](O)[C@H]3O)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D01 mock treatment 168240.0 -5030.0 -0.16 178800.0 23400.0 0.61 0.3205 0.5098 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D02 mock treatment 182160.0 8890.0 0.28 161920.0 6560.0 0.17 0.3154 0.9734 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D03 compound treatment 139920.0 -33300.0 -1.03 126040.0 -29300.0 -0.76 -1.2693 -0.9888 3199387 SMP2_000067 CCC1/C=C(/C)\CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)C(O)CC1=O)/C(=C/C4CCC(O)C(C4)OC)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D04 compound treatment 241760.0 68500.0 2.12 170000.0 14600.0 0.38 1.7696 0.8208 907555 SMP2_000068 CC1=C[C@H]2O[C@@H]3C[C@@H](O)C(C)(C43CO4)[C@@]2(CO)CC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D05 compound treatment 18000.0 -155000.0 -4.81 19160.0 -136000.0 -3.54 -5.9042 -0.9886 1962 SMP2_000069 CN(CC[C@H](N)CC(=O)N[C@H]1C=C[C@H](O[C@@H]1C(=O)O)n2ccc(N)nc2=O)C(=N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D06 compound treatment 131320.0 -41900.0 -1.3 155640.0 281.0 0.01 -0.9139 -0.7031 852250 SMP2_000070 C1CCC(NC1)c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D07 compound treatment 156760.0 -16500.0 -0.51 164480.0 9120.0 0.24 -0.1941 -0.3443 3076314 SMP2_000071 O[C@@H]1C=CC(Br)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D08 compound treatment 141600.0 -31700.0 -0.98 126560.0 -28800.0 -0.75 -1.2229 -0.9911 3076315 SMP2_000072 OC[C@H]1O[C@H](C[C@@H]1O)n2cc(I)c(O)nc2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D09 compound treatment 197440.0 24200.0 0.75 24280.0 -131000.0 -3.41 -1.8787 -0.5387 3199389 SMP2_000073 CCCCCCCc1c(C)c(O)cc2c3ccccc3[nH]c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D10 compound treatment 157200.0 -16100.0 -0.5 150680.0 -4680.0 -0.12 -0.438 -0.8547 3199390 SMP2_000074 COc1ccc(cc1)C(O)(C2CC2)c3cncnc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D11 compound treatment 11560.0 -162000.0 -5.01 10640.0 -145000.0 -3.76 -6.2018 -0.99 832324 SMP2_000075 COc1cc(OC)c2c(=O)c(C)c(CC[C@@H](C)[C@@H](C)[C@@H](C)[C@@H](C)/C=C/C=C/C(=C/C)/C)oc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D12 compound treatment 147560.0 -25700.0 -0.8 161000.0 5640.0 0.15 -0.4596 -0.5675 2085117 SMP2_000076 COc1ccc(OC)c2c(=S)c3ccccc3[nH]c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D13 compound treatment 136240.0 -37000.0 -1.15 134480.0 -20900.0 -0.54 -1.1949 -0.9415 251 SMP2_000077 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D14 compound treatment 12960.0 -160000.0 -4.97 10680.0 -145000.0 -3.76 -6.1704 -0.9906 2007 SMP2_000078 CO[C@@H]1[C@@H](OC(=O)c2ccc(C)[nH]2)[C@@H](O)[C@H](CC1(C)C)Oc3ccc4CC(NC(=O)c5[nH]cc(CC(=O)Nc6cc7ccc(O[C@@H]8OC(C)(C)[C@H](OC)[C@@H](OC(=O)c9ccc(C)[nH]9)[C@H]8O)c(C)c7oc6=O)c5C)C(=O)Oc4c3C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D15 compound treatment 136960.0 -36300.0 -1.12 150760.0 -4600.0 -0.12 -0.88 -0.7778 751 SMP2_000079 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D16 compound treatment 138240.0 -35000.0 -1.09 130680.0 -24700.0 -0.64 -1.2209 -0.9685 3076316 SMP2_000080 Oc1cc(ccc1C(=O)c2ccccc2)N3CCOCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D17 compound treatment 172160.0 -1110.0 -0.03 139520.0 -15800.0 -0.41 -0.3153 -0.7635 3076317 SMP2_000081 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@H](C[C@H](C[C@@H](C)C\C(=C/[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC)[C@H](C[C@H]4C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D18 compound treatment 156960.0 -16300.0 -0.51 147800.0 -7560.0 -0.2 -0.4962 -0.9152 1392 SMP2_000082 CNC(C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D19 compound treatment 138520.0 -34700.0 -1.08 163840.0 8480.0 0.22 -0.6055 -0.551 610 SMP2_000083 O=S(=O)(N1CCCNCC1)c2cccc3cnccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D20 compound treatment 113120.0 -60100.0 -1.86 149600.0 -5760.0 -0.15 -1.4236 -0.7614 3076318 SMP2_000084 Oc1nccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D21 compound treatment 9400.0 -164000.0 -5.08 50040.0 -105000.0 -2.74 -5.5252 -0.9579 616 SMP2_000085 COc1cc(O)c2c(=O)c(OC)c3CC(C)C(C(=O)C)c4c(OC)c(=O)c5c(O)cc(OC)c6c1c2c3c4c56 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D22 compound treatment 144000.0 -29300.0 -0.91 24840.0 -131000.0 -3.39 -3.0392 -0.8658 1096695 SMP2_000086 Oc1ccc(CC=C)cc1c2cc(CC=C)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D23 compound treatment 168240.0 -5030.0 -0.16 135080.0 -20300.0 -0.53 -0.4827 -0.8786 3176136 SMP2_000087 C[C@@H]1C2NCC(C)C[C@H]2O[C@@]31CCC4C5CC=C6CC(O)CCC6(C)C5C(=O)C4=C3C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 D24 compound treatment 118320.0 -54900.0 -1.7 121640.0 -33700.0 -0.88 -1.8234 -0.9523 3076319 SMP2_000088 Nc1nc(OCC2CCCCC2)c3[nH]cnc3n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E01 mock treatment 210320.0 37100.0 1.15 188400.0 33000.0 0.86 1.4188 0.9898 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E02 mock treatment 175960.0 2690.0 0.08 151280.0 -4080.0 -0.11 -0.016 -0.1184 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E03 compound treatment 148560.0 -24700.0 -0.77 144640.0 -10700.0 -0.28 -0.7383 -0.9062 445 SMP2_000089 NC(=O)c1cccc(N)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E04 compound treatment 46280.0 -127000.0 -3.93 40360.0 -115000.0 -2.99 -4.8951 -0.9908 1057045 SMP2_000090 COC(=O)c1ccc(O)c2nc3c(C=O)c(O)cc(O)c3nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E05 compound treatment 139680.0 -33600.0 -1.04 132480.0 -22900.0 -0.59 -1.1562 -0.9647 1949 SMP2_000091 NOC(=O)C1=CC(=C(c2ccc(O)c(c2)C(=O)ON)c3ccc(O)c(c3)C(=O)ON)C=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E06 compound treatment 92160.0 -81100.0 -2.51 80840.0 -74500.0 -1.94 -3.1461 -0.9917 2180 SMP2_000092 COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C(C)C)c4n2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E07 compound treatment 53600.0 -120000.0 -3.71 56640.0 -98700.0 -2.56 -4.4356 -0.9838 1020463 SMP2_000093 Oc1cc2ccc(=O)oc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E08 compound treatment 122680.0 -50600.0 -1.57 145560.0 -9800.0 -0.25 -1.2884 -0.8113 3076699 SMP2_000094 CN1CCC[C@H]1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E09 compound treatment 11400.0 -162000.0 -5.02 8920.0 -146000.0 -3.8 -6.2369 -0.9907 1694 SMP2_000095 Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E10 compound treatment 32520.0 -141000.0 -4.36 36360.0 -119000.0 -3.09 -5.27 -0.9858 2345 SMP2_000096 Nc1ncnc2n(ccc12)[C@@H]3O[C@H](CO)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E11 compound treatment 146840.0 -26400.0 -0.82 181720.0 26400.0 0.68 -0.0947 -0.0887 3199487 SMP2_000097 C[C@@H]1CC[C@@]2(C[C@H](C)C3C(=CCC4[C@@]3(C)C[C@@H](O)C5[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]45C)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E12 compound treatment 131080.0 -42200.0 -1.31 133240.0 -22100.0 -0.57 -1.3307 -0.9319 2240 SMP2_000098 CC(C)C[C@H](NP(=O)(O)OC1OC(C)C(O)C(O)C1O)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E13 compound treatment 166200.0 -7070.0 -0.22 145840.0 -9520.0 -0.25 -0.3297 -0.9982 1000145 SMP2_000099 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E14 compound treatment 13840.0 -159000.0 -4.94 11200.0 -144000.0 -3.75 -6.1415 -0.9907 267 SMP2_000100 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E15 compound treatment 186360.0 13100.0 0.41 154240.0 -1120.0 -0.03 0.2663 0.6548 1114632 SMP2_000101 CC1OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)C(O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E16 compound treatment 121520.0 -51700.0 -1.6 76440.0 -78900.0 -2.05 -2.5837 -0.9926 1000121 SMP2_000102 C/C(=C\CO)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E17 compound treatment 92040.0 -81200.0 -2.52 95720.0 -59600.0 -1.55 -2.8754 -0.9729 1599897 SMP2_000103 O=c1n2CCc3c([nH]c4ccccc34)-c2nc5ccccc15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E18 compound treatment 140760.0 -32500.0 -1.01 151760.0 -3600.0 -0.09 -0.7784 -0.7694 2354 SMP2_000104 COc1ccc2C3C4[C@H](CC(C)(C)OO[C@H](C=C(C)C)N4c2c1)N5C(=O)[C@@H]6CCCN6C(=O)[C@]5(O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E19 compound treatment 190520.0 17300.0 0.53 147800.0 -7560.0 -0.2 0.2391 0.4199 1001870 SMP2_000105 C/C(=C/C(=O)O)/C=C/[C@@]1(O)C(=CC(=O)CC1(C)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E20 compound treatment 146000.0 -27300.0 -0.84 152040.0 -3320.0 -0.09 -0.6584 -0.7752 296 SMP2_000106 Nc1ncnc2N(=CNc21)C3CCCO3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E21 compound treatment 128440.0 -44800.0 -1.39 149040.0 -6320.0 -0.16 -1.0983 -0.7852 600 SMP2_000107 COC(=O)/C=C/c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E22 compound treatment 24880.0 -148000.0 -4.6 26120.0 -129000.0 -3.36 -5.6255 -0.9881 2327 SMP2_000108 CCC(C)C1NC2C=Cc3c(cc(nc3C2O)C(=O)OC(C)C(NCC(=O)c4csc(n4)C(NC(=O)c5csc(n5)/C(=C\C)/NC(=O)C(NC(=O)c6csc(n6)C7(CCC(=NC7)c8nc(cs8)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)NC(=C)C(C)NC(=O)C(=C)NCC(C)NC1=O)C(C)O)C(C)(O)C(C)O)c9nccs9)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E23 compound treatment 7280.0 -166000.0 -5.14 6840.0 -149000.0 -3.86 -6.3654 -0.99 3076759 SMP2_000109 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](COP(=O)(O)OCC[N+](C)(C)C)NC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 E24 compound treatment 96440.0 -76800.0 -2.38 105760.0 -49600.0 -1.29 -2.5945 -0.9585 3199491 SMP2_000110 C/C=C/C1OC2=C(C(=O)C[C@H](C)O2)C(=O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F01 mock treatment 203120.0 29900.0 0.92 157640.0 2280.0 0.06 0.6959 0.7509 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F02 mock treatment 142320.0 -30900.0 -0.96 166680.0 11300.0 0.29 -0.4701 -0.4686 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F03 compound treatment 153680.0 -19600.0 -0.61 160600.0 5240.0 0.14 -0.3329 -0.5351 907179 SMP2_000111 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)C(O)CC1(C)C)/C=C/C=C(\C)/C=C/C2=C(C)C(=O)C(O)CC2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F04 compound treatment 28400.0 -145000.0 -4.49 24640.0 -131000.0 -3.4 -5.5756 -0.9905 3076760 SMP2_000112 COc1cc(O)c2c3oc4cc(O)c(O)cc4c3c(=O)oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F05 compound treatment 145240.0 -28000.0 -0.87 153080.0 -2280.0 -0.06 -0.6559 -0.7536 328 SMP2_000113 C/C=C(/C)\C=C\1/CN=C2N(CCC2(O)C1=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F06 compound treatment 156760.0 -16500.0 -0.51 169000.0 13600.0 0.35 -0.1111 -0.1785 3076761 SMP2_000114 CNCC/C=C/1\c2ccccc2CC(O)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F07 compound treatment 146400.0 -26900.0 -0.83 151760.0 -3600.0 -0.09 -0.6548 -0.7816 3199493 SMP2_000115 CCC/C=C/C=C/C(=O)O[C@H]1\C(=C\C(=O)OC)\C[C@H]2C[C@@H](OC(=O)C[C@H](O)C[C@H]3C[C@H](OC(=O)C)C(C)(C)[C@](O)(C[C@@H]4C/C(=C/C(=O)OC)/C[C@@H](O4)/C=C\C(C)(C)[C@]1(O)O2)O3)[C@@H](C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F08 compound treatment 144760.0 -28500.0 -0.88 132080.0 -23300.0 -0.6 -1.0523 -0.9829 1046629 SMP2_000116 Nc1cc2c3ccccc3ccc2c4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F09 compound treatment 11280.0 -162000.0 -5.02 11560.0 -144000.0 -3.74 -6.191 -0.9894 1037664 SMP2_000117 CSCS(=O)CC(CO)NC(=O)C=Cc1c(C)nc(O)nc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F10 compound treatment 135400.0 -37900.0 -1.17 150120.0 -5240.0 -0.14 -0.9259 -0.7839 1943 SMP2_000118 CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@@]4(C)O[C@H](CO)[C@@H](N)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F11 compound treatment 130880.0 -42400.0 -1.31 134560.0 -20800.0 -0.54 -1.3108 -0.923 3199494 SMP2_000119 CC[C@@H]1C[C@@]1(NC(=O)C2=C[C@H](CC)C[C@H]3[C@@H]2CCC3=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F12 compound treatment 12000.0 -161000.0 -5.0 10840.0 -145000.0 -3.76 -6.1885 -0.9901 1320 SMP2_000120 C[C@]1(CC[C@]2(C)CC[C@]3(C)C4=CC=C5C=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F13 compound treatment 87320.0 -85900.0 -2.66 94040.0 -61300.0 -1.59 -3.0097 -0.9698 745 SMP2_000121 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F14 compound treatment 10400.0 -163000.0 -5.05 10080.0 -145000.0 -3.77 -6.2375 -0.9898 2008 SMP2_000122 CC1=C(SCCO)C(=O)c2ccccc2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F15 compound treatment 169280.0 -3990.0 -0.12 162720.0 7360.0 0.19 0.0479 0.2102 3199495 SMP2_000123 CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)COP(=O)(O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F16 compound treatment 133880.0 -39400.0 -1.22 148120.0 -7240.0 -0.19 -0.996 -0.8066 3076763 SMP2_000124 Oc1ccc2c(Oc3cc(O)ccc3C42OC(=O)c5ccc(Nc6nc(Cl)nc(Cl)n6)cc54)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F17 compound treatment 133960.0 -39300.0 -1.22 156560.0 1200.0 0.03 -0.8391 -0.6888 1433 SMP2_000125 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F18 compound treatment 132680.0 -40600.0 -1.26 145520.0 -9840.0 -0.26 -1.07 -0.8338 1100216 SMP2_000126 CC(=CCCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC54C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F19 compound treatment 11600.0 -162000.0 -5.01 10520.0 -145000.0 -3.76 -6.2031 -0.9901 3000453 SMP2_000127 C[C@@H]1CC2OC(=O)C(=C)C2[C@H](O)[C@@]3(C)[C@H]1C=CC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F20 compound treatment 144160.0 -29100.0 -0.9 132040.0 -23300.0 -0.61 -1.0662 -0.9813 3060680 SMP2_000128 Oc1ccccc1N2CC=C(NC2=O)c3cccc(c3)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F21 compound treatment 9360.0 -164000.0 -5.08 9400.0 -146000.0 -3.79 -6.2728 -0.9897 1907753 SMP2_000129 CC[C@@H]1[C@H](C)C[C@@H]2[C@H]3C[C@H]4CCC(=O)C5=C(O)[C@H](CCCNC(=O)/C=C\C[C@@H]4[C@H]3C=C[C@@H]12)NC5=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F22 compound treatment 7640.0 -166000.0 -5.13 7040.0 -148000.0 -3.85 -6.3538 -0.99 1001972 SMP2_000130 CCCC[C@@H](C)/C=C(\C)/C=C(\C)/C(=O)NC1=C[C@@](O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)[C@@H]3O[C@@H]3C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F23 compound treatment 155920.0 -17300.0 -0.54 205040.0 49700.0 1.29 0.5327 0.3809 3076765 SMP2_000131 CO[C@H]1[C@@H](CC(=O)O[C@H](C)C/C=C\C=C/[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(=O)CC(C)C)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 F24 compound treatment 36520.0 -137000.0 -4.24 22680.0 -133000.0 -3.45 -5.4337 -0.9948 288 SMP2_000132 C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G01 mock treatment 176840.0 3570.0 0.11 166960.0 11600.0 0.3 0.2914 0.9075 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G02 mock treatment 157040.0 -16200.0 -0.5 141200.0 -14200.0 -0.37 -0.6157 -0.9882 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G03 compound treatment 143240.0 -30000.0 -0.93 163240.0 7880.0 0.2 -0.5131 -0.5386 2407 SMP2_000133 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ncc(C)s3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G04 compound treatment 97600.0 -75700.0 -2.34 107560.0 -47800.0 -1.24 -2.536 -0.9558 907364 SMP2_000134 CCC(C(=O)NC/C=C\C=C(\C)/C(OC)C(C)C1OC(\C=C/C=C\C=C(\C)/C(=O)c2c(O)cc[nH]c2=O)C(O)C1O)C3(O)OC(\C=C/C=C\C)C(C)(C)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G05 compound treatment 138560.0 -34700.0 -1.08 143880.0 -11500.0 -0.3 -0.9713 -0.8704 1978 SMP2_000135 OC(=O)/C=C/c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G06 compound treatment 10880.0 -162000.0 -5.03 10480.0 -145000.0 -3.76 -6.2196 -0.9898 3076766 SMP2_000136 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G07 compound treatment 112800.0 -60500.0 -1.87 119000.0 -36400.0 -0.94 -1.9928 -0.9497 1117 SMP2_000137 Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cnc2[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G08 compound treatment 117800.0 -55500.0 -1.72 121640.0 -33700.0 -0.88 -1.8348 -0.9511 313 SMP2_000138 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G09 compound treatment 114400.0 -58900.0 -1.82 153920.0 -1440.0 -0.04 -1.3162 -0.7214 3076819 SMP2_000139 COCC(=O)c1ncn-2c1[C@@H]3CCNC3C(=O)c4cc(OC)ccc42 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G10 compound treatment 95840.0 -77400.0 -2.4 87440.0 -67900.0 -1.76 -2.9442 -0.9886 3199591 SMP2_000140 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCCC)COC(=O)Cc5ccc(O)c(OC)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G11 compound treatment 136160.0 -37100.0 -1.15 124080.0 -31300.0 -0.81 -1.3877 -0.9856 939 SMP2_000141 Cc1cccc(Nc2ccccc2C(=O)O)c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G12 compound treatment 155800.0 -17500.0 -0.54 99840.0 -55500.0 -1.44 -1.4027 -0.9104 3076821 SMP2_000142 CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G13 compound treatment 109840.0 -63400.0 -1.97 127360.0 -28000.0 -0.73 -1.9041 -0.9086 1012954 SMP2_000143 OC(Cc1ccncc1)C(Cl)(Cl)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G14 compound treatment 107400.0 -65900.0 -2.04 117200.0 -38200.0 -0.99 -2.1442 -0.945 4637 SMP2_000144 C[C@@H]1C[C@]2(OC(=O)C)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G15 compound treatment 119160.0 -54100.0 -1.68 126600.0 -28800.0 -0.75 -1.7139 -0.9337 942 SMP2_000145 OC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G16 compound treatment 11640.0 -162000.0 -5.01 11800.0 -144000.0 -3.73 -6.1787 -0.9895 3199592 SMP2_000146 CCCC[C@]1(CC[C@]2(CC[C@H](C)[C@@H](C/C=C(\C)/C=C/[C@H](O)[C@@H](C)/C=C/C(=O)O)O2)O[C@H]1\C=C\C(=C\C(=O)O)\C)OC(=O)CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G17 compound treatment 141640.0 -31600.0 -0.98 149520.0 -5840.0 -0.15 -0.8002 -0.807 1011013 SMP2_000147 Nc1ccc2nc3ccc(N)cc3[s+]c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G18 compound treatment 115360.0 -57900.0 -1.79 132600.0 -22800.0 -0.59 -1.6869 -0.8929 3076824 SMP2_000148 NC(=O)OCC1N=C(N)N2CCC(O)(O)C32NC(=NC13)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G19 compound treatment 146160.0 -27100.0 -0.84 152160.0 -3200.0 -0.08 -0.6527 -0.7733 3199593 SMP2_000149 COc1cc(ccc1O)[C@H]2Oc3cc(ccc3O[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G20 compound treatment 112320.0 -60900.0 -1.89 130840.0 -24500.0 -0.64 -1.7858 -0.896 3185114 SMP2_000150 CC[C@]1(C=CCN2CC[C@]3([C@H]4N(C)c5cc(OC)ccc53)[C@@H]21)[C@@H](OC(=O)C)[C@]4(O)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G21 compound treatment 130600.0 -42700.0 -1.32 154360.0 -999.0 -0.03 -0.9532 -0.7208 3199594 SMP2_000151 C[C@@H]1[C@@H](O)[C@]2(O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G22 compound treatment 122880.0 -50400.0 -1.56 129960.0 -25400.0 -0.66 -1.5706 -0.9266 3076825 SMP2_000152 NC(=O)C1CCCN1C(=O)C(Cc2c[nH]cn2)NC(=O)C3CCC(=O)N3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G23 compound treatment 26320.0 -147000.0 -4.55 24280.0 -131000.0 -3.41 -5.6278 -0.9898 1095351 SMP2_000153 COC1=C(Br)C(O)C(O)(CC#N)C=C1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 G24 compound treatment 126280.0 -47000.0 -1.46 114160.0 -41200.0 -1.07 -1.7864 -0.9886 3 SMP2_000154 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H01 mock treatment 182040.0 8770.0 0.27 159400.0 4040.0 0.11 0.2664 0.9144 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H02 mock treatment 160080.0 -13200.0 -0.41 157320.0 1960.0 0.05 -0.2529 -0.6142 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H03 compound treatment 159880.0 -13400.0 -0.41 147920.0 -7440.0 -0.19 -0.43 -0.9396 3199595 SMP2_000155 CCC(C)C(NC(=O)C1CC(=O)NCC(=O)NC(Cc2ccccc2)C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(Cc3c[nH]c4ccccc34)C(=O)NCC(=O)NC(CC(=O)N)C(=O)N1)C(=O)NC(Cc5ccccc5)C(=O)NCC(=O)NC(Cc6c[nH]cn6)C(=O)NC(Cc7ccc(O)cc7)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(Cc8ccccc8)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H04 compound treatment 10120.0 -163000.0 -5.06 9600.0 -146000.0 -3.79 -6.2524 -0.9899 1303231 SMP2_000156 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H05 compound treatment 123240.0 -50000.0 -1.55 129560.0 -25800.0 -0.67 -1.5701 -0.9297 3076826 SMP2_000157 Nc1ccccc1NC(=O)CCCCCCC(=O)Nc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H06 compound treatment 148320.0 -24900.0 -0.77 140320.0 -15000.0 -0.39 -0.8229 -0.9501 3076827 SMP2_000158 OC[C@H]1CC2CCN1CC2C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H07 compound treatment 17440.0 -156000.0 -4.83 20880.0 -134000.0 -3.49 -5.8848 -0.9874 3199596 SMP2_000159 OC(=O)c1cc(/C=C/c2ccc(/C=C/c3ccc(O)c(c3)C(=O)O)c(Br)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H08 compound treatment 16800.0 -156000.0 -4.85 17880.0 -137000.0 -3.57 -5.954 -0.9887 1088673 SMP2_000160 CC(C)C1NC(=O)C(NC(=O)c2cc(N)c(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H09 compound treatment 131320.0 -41900.0 -1.3 125400.0 -30000.0 -0.78 -1.4695 -0.9699 3069011 SMP2_000161 NCCC(=O)NCCc1c[nH]cn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H10 compound treatment 133200.0 -40100.0 -1.24 120480.0 -34900.0 -0.91 -1.5187 -0.988 1025 SMP2_000162 CC(C)CC(=O)OC1C(O[C@@H]2C[C@H]([C@H]3CC[C@]4(C[C@@H]5CC[C@H]4[C@]3(C)C2)[C@@H](O)C5=C)C(=O)O)OC(CO)C(OS(=O)(=O)O)C1OS(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H11 compound treatment 154320.0 -18900.0 -0.59 148880.0 -6480.0 -0.17 -0.5342 -0.8746 1018447 SMP2_000163 Oc1ccc2c(c1)oc3c2c(=O)oc4cc(O)ccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H12 compound treatment 127600.0 -45700.0 -1.42 152240.0 -3120.0 -0.08 -1.0579 -0.7464 1000068 SMP2_000164 CC1=C(N2[C@H](SC1)C(NC(=O)C(N)c3ccccc3)C2=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H13 compound treatment 111400.0 -61900.0 -1.92 108440.0 -46900.0 -1.22 -2.2175 -0.9761 526 SMP2_000165 C[C@@H](O)[C@@H]1O[C@H]1/C=C/[C@@H]2O[C@H]2[C@H](O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H14 compound treatment 100280.0 -73000.0 -2.26 104880.0 -50500.0 -1.31 -2.5266 -0.9664 460 SMP2_000166 CCC1NC(=O)C([C@H](O)[C@H](C)C/C=C/C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H15 compound treatment 134280.0 -39000.0 -1.21 144760.0 -10600.0 -0.28 -1.0489 -0.8466 907301 SMP2_000167 CCC(C)C(O)C(C)C(=O)C(C)/C=C(\C)/CC(C)C1OC(=O)C1CC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H16 compound treatment 134920.0 -38300.0 -1.19 134520.0 -20800.0 -0.54 -1.223 -0.9367 3076266 SMP2_000168 CO[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H17 compound treatment 155760.0 -17500.0 -0.54 128800.0 -26600.0 -0.69 -0.8716 -0.9929 1001938 SMP2_000169 COC[C@H]1CC[C@H]2[C@@H](C)[C@@H](O)[C@H](OC3OC(COC(C)(C)C=C)[C@H](O)C(OC(=O)C)[C@@H]3O)C4=C(CC(O)[C@]4(C)C=C12)C(C)COC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H18 compound treatment 11080.0 -162000.0 -5.03 11040.0 -144000.0 -3.75 -6.205 -0.9896 829 SMP2_000170 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H19 compound treatment 122200.0 -51100.0 -1.58 104800.0 -50600.0 -1.31 -2.0478 -0.9957 2334 SMP2_000171 C/C(=C\1/C(=O)NC(Cc2ccccc2)C1=O)/Nc3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H20 compound treatment 125600.0 -47700.0 -1.48 129960.0 -25400.0 -0.66 -1.511 -0.9341 2109 SMP2_000172 OCc1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H21 compound treatment 102800.0 -70500.0 -2.18 100880.0 -54500.0 -1.42 -2.5448 -0.978 2106 SMP2_000173 COC1=CC(=O)C(=C(C[C@]2(C)[C@@H](C)CC[C@@]3(C)[C@H]2CCCC3=C)C1=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H22 compound treatment 121280.0 -52000.0 -1.61 126640.0 -28700.0 -0.75 -1.6667 -0.9388 1260 SMP2_000174 N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H23 compound treatment 15640.0 -158000.0 -4.88 14840.0 -141000.0 -3.65 -6.0352 -0.9897 3076270 SMP2_000175 C[C@]12C=Cc3occc3C2CC[C@]4(C[C@H]5CCC41)C[C@]5(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 H24 compound treatment 178480.0 5210.0 0.16 150480.0 -4880.0 -0.13 0.0245 0.1196 3199601 SMP2_000176 CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC1=O)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I01 mock treatment 180000.0 6730.0 0.21 156640.0 1280.0 0.03 0.171 0.8097 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I02 mock treatment 152280.0 -21000.0 -0.65 138080.0 -17300.0 -0.45 -0.7773 -0.9836 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I03 compound treatment 130880.0 -42400.0 -1.31 145840.0 -9520.0 -0.25 -1.1036 -0.8257 3076271 SMP2_000177 OC(=O)/C=C/c1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I04 compound treatment 8800.0 -164000.0 -5.1 9160.0 -146000.0 -3.8 -6.2894 -0.9895 3199602 SMP2_000178 C/C(=C\CCC1=CC(=O)OC1O)/CC/C=C(\C)/CCC2=C(C)CCCC2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I05 compound treatment 7120.0 -166000.0 -5.15 8240.0 -147000.0 -3.82 -6.3432 -0.9893 1135 SMP2_000179 OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I06 compound treatment 131000.0 -42300.0 -1.31 127680.0 -27700.0 -0.72 -1.4346 -0.9602 252 SMP2_000180 CCCCCCOC(=O)[C@]1(O)C[C@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I07 compound treatment 123160.0 -50100.0 -1.55 127520.0 -27800.0 -0.72 -1.6093 -0.9396 3076272 SMP2_000181 COC(=O)C1=CO[C@@H](O[C@@H]2OC(CO)[C@H](O)[C@@H](O)[C@H]2O)[C@H]3[C@@H]1CC=C3CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I08 compound treatment 132600.0 -40700.0 -1.26 136680.0 -18700.0 -0.49 -1.2342 -0.914 3199603 SMP2_000182 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCCCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I09 compound treatment 117120.0 -56100.0 -1.74 136360.0 -19000.0 -0.49 -1.5792 -0.8733 2129 SMP2_000183 OCC(O)C1OC(=O)C(=C1O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I10 compound treatment 74800.0 -98500.0 -3.05 86720.0 -68600.0 -1.78 -3.4184 -0.9673 3199692 SMP2_000184 CCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCC)COC(=O)Cc5ccc(O)c(OC)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I11 compound treatment 40720.0 -133000.0 -4.11 41400.0 -114000.0 -2.96 -4.9978 -0.9871 1865 SMP2_000185 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I12 mock treatment 125800.0 -47500.0 -1.47 116400.0 -39000.0 -1.01 -1.7558 -0.9834 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I13 compound treatment 112360.0 -60900.0 -1.89 120040.0 -35300.0 -0.92 -1.9834 -0.9451 3472730 SMP2_000186 CC12CCC3C(CC=C4CC(O)CCC34C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I14 compound treatment 132600.0 -40700.0 -1.26 117840.0 -37500.0 -0.97 -1.5803 -0.992 3076274 SMP2_000187 Oc1ccc(cc1)C2COc3cc(O)ccc3C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I15 compound treatment 9560.0 -164000.0 -5.07 10280.0 -145000.0 -3.77 -6.2522 -0.9893 2288 SMP2_000188 CC(=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I16 compound treatment 105680.0 -67600.0 -2.09 112600.0 -42800.0 -1.11 -2.2664 -0.956 3199693 SMP2_000189 COC(C(C)C1CC(O)C2(C)OC2/C=C\C(C)C3CC(CC(=O)O3)CC4OC4C(=O)O1)C(=CC=CC(=Cc5coc(C)n5)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I17 compound treatment 128160.0 -45100.0 -1.4 145960.0 -9400.0 -0.24 -1.161 -0.8183 1025605 SMP2_000190 OCCN(CCO)CCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I18 compound treatment 97720.0 -75500.0 -2.34 106560.0 -48800.0 -1.27 -2.5518 -0.9585 3060146 SMP2_000191 Oc1ccc(cc1)c2nc(c([nH]2)c3ccc(F)cc3)c4ccncc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I19 compound treatment 130840.0 -42400.0 -1.31 110880.0 -44500.0 -1.16 -1.7468 -0.9979 1874 SMP2_000192 Oc1cccc2c(O)nccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I20 compound treatment 94120.0 -79100.0 -2.45 109920.0 -45400.0 -1.18 -2.5689 -0.9438 1080610 SMP2_000193 COc1ccc(O)c2c(=O)c3c(OC)cc4OC5OC=CC5c4c3oc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I21 compound treatment 144240.0 -29000.0 -0.9 144520.0 -10800.0 -0.28 -0.8351 -0.8861 2290 SMP2_000194 C[C@]1(CC(N)CCC(N)C(=O)O)O[C@](C)([C@@H](O)[C@H]1O)n2cnc3c(N)ncnc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I22 compound treatment 108040.0 -65200.0 -2.02 98800.0 -56600.0 -1.47 -2.4682 -0.9877 3076167 SMP2_000195 CC(C)C1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)/C=C(/C)\C=C/CNC(=O)\C=C/C1C)n3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I23 compound treatment 123120.0 -50100.0 -1.55 142200.0 -13200.0 -0.34 -1.3405 -0.8425 1077786 SMP2_000196 CC(C)CC1N2C(=O)C(NC(=O)C3CN(C)C4Cc5c[nH]c6cccc(C4=C3)c56)(OC2(O)C7CCCN7C1=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 I24 compound treatment 114800.0 -58500.0 -1.81 36280.0 -119000.0 -3.09 -3.4688 -0.9675 325 SMP2_000197 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J01 mock treatment 194680.0 21400.0 0.66 150160.0 -5200.0 -0.14 0.3736 0.5518 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J02 mock treatment 164680.0 -8590.0 -0.27 139000.0 -16400.0 -0.43 -0.4887 -0.9746 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J03 compound treatment 140560.0 -32700.0 -1.01 144720.0 -10600.0 -0.28 -0.9121 -0.8683 3076170 SMP2_000198 OC[C@@H]1[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J04 compound treatment 161800.0 -11500.0 -0.36 129240.0 -26100.0 -0.68 -0.7311 -0.9544 677 SMP2_000199 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J05 compound treatment 123080.0 -50200.0 -1.56 124600.0 -30800.0 -0.8 -1.6647 -0.9521 2060246 SMP2_000200 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C/C=C/3\[C@H](O)COC3=O)C(=C)CCC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J06 compound treatment 184880.0 11600.0 0.36 189160.0 33800.0 0.88 0.8754 0.9224 414 SMP2_000201 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J07 compound treatment 121680.0 -51600.0 -1.6 144400.0 -11000.0 -0.28 -1.3316 -0.8202 1972 SMP2_000202 COC(=O)/C(=C\Nc1ccc(Oc2ccccc2OC(C)C)nc1)/NC(=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J08 compound treatment 129280.0 -44000.0 -1.36 125480.0 -29900.0 -0.78 -1.5127 -0.9644 3189311 SMP2_000203 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](N)C2=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J09 compound treatment 9040.0 -164000.0 -5.09 10680.0 -145000.0 -3.76 -6.2563 -0.9889 2109607 SMP2_000204 CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(=O)O)c2c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J10 compound treatment 10160.0 -163000.0 -5.05 17600.0 -138000.0 -3.58 -6.1046 -0.9857 1960 SMP2_000205 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J11 compound treatment 92640.0 -80600.0 -2.5 111080.0 -44300.0 -1.15 -2.58 -0.9381 3199694 SMP2_000206 CC1[C@H]2NC[C@@H](C)C[C@H]2O[C@@]31CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J12 compound treatment 7160.0 -166000.0 -5.15 8200.0 -147000.0 -3.82 -6.343 -0.9893 874122 SMP2_000207 COc1c(O)c2c(=O)cc3OCOc4cc(O)c5c(=O)c(OC)c(CC(C)O)c6c(c1CC(C)O)c2c3c4c56 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J13 compound treatment 109000.0 -64300.0 -1.99 134880.0 -20500.0 -0.53 -1.7843 -0.8657 1301 SMP2_000208 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J14 compound treatment 90000.0 -83300.0 -2.58 88160.0 -67200.0 -1.75 -3.059 -0.9819 1001900 SMP2_000209 Nc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J15 compound treatment 128320.0 -44900.0 -1.39 111400.0 -44000.0 -1.14 -1.7924 -0.9952 2056 SMP2_000210 CC(C)CC(NC(=O)NC(C1CCNC(=N1)N)C(=O)NC(CCC(=O)N)C(=O)NC(C)C=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J16 compound treatment 71240.0 -102000.0 -3.16 125560.0 -29800.0 -0.77 -2.7829 -0.855 599 SMP2_000211 Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J17 compound treatment 137200.0 -36100.0 -1.12 136040.0 -19300.0 -0.5 -1.1452 -0.9347 162 SMP2_000212 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J18 compound treatment 133560.0 -39700.0 -1.23 165520.0 10200.0 0.26 -0.6833 -0.543 3076285 SMP2_000213 CN1C(=O)/C(=C/2\Nc3ccccc3\C2=N\O)/c4ccc(Br)cc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J19 compound treatment 42200.0 -131000.0 -4.06 48040.0 -107000.0 -2.79 -4.8433 -0.9832 3199695 SMP2_000214 CC1O[C@@H](O[C@H]2C[C@@H](C=O)C3C(CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)c6ccc(=O)oc6)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O[C@@H]7OC(CO)[C@@H](O)[C@@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J20 compound treatment 97680.0 -75600.0 -2.34 86720.0 -68600.0 -1.78 -2.9172 -0.991 3076287 SMP2_000215 COc1cc(O)c(CC=C(C)C)c2OC(CC(=O)c12)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J21 compound treatment 131600.0 -41700.0 -1.29 145960.0 -9400.0 -0.24 -1.0856 -0.8262 2411 SMP2_000216 NCC1O[C@@H](O[C@@H]2[C@H](N)C[C@@H](N)C(O[C@H]3OC(CO)[C@@H](O)[C@@H](N)[C@H]3O)C2O)[C@H](N)C[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J22 compound treatment 141640.0 -31600.0 -0.98 170960.0 15600.0 0.41 -0.4063 -0.3831 3199697 SMP2_000217 CCC(=O)O[C@H]1C(C)O[C@](C)(C[C@]1(C)O)O[C@@H]2C(C)O[C@@H](CO[C@@H]3[C@@H](C)[C@@H](CC(=O)O[C@H](C)C/C=C\C=C/[C@H](O)[C@H](C)C[C@@H]3CC(=O)C)OC(=O)CC)[C@H](O)[C@@H]2N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J23 compound treatment 7840.0 -165000.0 -5.13 8200.0 -147000.0 -3.82 -6.3281 -0.9896 3076290 SMP2_000218 C[C@@H]1[C@H](O)[C@@H](C)[C@H]2O[C@@H]1CC[C@H](C)/C=C(/C)\C[C@@H](C)C[C@H](C)[C@]3(O)OC4=C(C)C(=O)C(=C2C4=C3)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 J24 compound treatment 120080.0 -53200.0 -1.65 83600.0 -71800.0 -1.86 -2.4837 -0.9981 3199698 SMP2_000219 CC(NC(=O)C(NC(=O)c1nc(nc(N)c1C)C(CC(=O)N)NCC(N)C(=O)N)C(OC2OC(CO)C(O)C(O)C2(C)OC3OC(CO)C(O)C(O)(C3O)C(=O)N)c4cnc[nH]4)C(O)C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)c6nc(cs6)C(=O)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K01 mock treatment 157000.0 -16300.0 -0.5 140800.0 -14600.0 -0.38 -0.6239 -0.99 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K02 mock treatment 142400.0 -30900.0 -0.96 120800.0 -34600.0 -0.9 -1.3112 -0.9995 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K03 compound treatment 22400.0 -151000.0 -4.67 27560.0 -128000.0 -3.32 -5.6534 -0.986 3076443 SMP2_000220 CC(C)CCC[C@@H](C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K04 compound treatment 10240.0 -163000.0 -5.05 17360.0 -138000.0 -3.59 -6.1072 -0.9859 25 SMP2_000221 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K05 compound treatment 81960.0 -91300.0 -2.83 94040.0 -61300.0 -1.59 -3.1271 -0.9631 3076448 SMP2_000222 CCC1=CC2C[C@@H]3c4[nH]c5ccccc5c4CCN(C2)[C@@]31C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K06 compound treatment 7960.0 -165000.0 -5.12 9880.0 -145000.0 -3.78 -6.2946 -0.9888 309 SMP2_000223 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K07 compound treatment 7520.0 -166000.0 -5.14 10880.0 -144000.0 -3.75 -6.2859 -0.9881 1000097 SMP2_000224 Cc1c(C)c2OC(C)(COc3ccc(CC4SC(=O)NC4=O)cc3)CCc2c(C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K08 compound treatment 47920.0 -125000.0 -3.88 80520.0 -74800.0 -1.94 -4.1213 -0.9489 2113458 SMP2_000225 CCC(=O)NCCc1c2scnc2c3nccc4c5ccccc5[nH]c1c43 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K09 compound treatment 146760.0 -26500.0 -0.82 178280.0 22900.0 0.6 -0.1597 -0.1574 3076491 SMP2_000226 CCCCCCCCCCCCCCCC(=O)OCC(O)[C@H]1OC(=O)C(=C1O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K10 compound treatment 125400.0 -47900.0 -1.48 110640.0 -44700.0 -1.16 -1.8704 -0.9927 3184 SMP2_000227 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O/C(=C\CCCC(=O)O)/C[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K11 compound treatment 17520.0 -156000.0 -4.83 22520.0 -133000.0 -3.45 -5.8529 -0.9865 1313 SMP2_000228 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K12 compound treatment 110920.0 -62300.0 -1.93 117880.0 -37500.0 -0.97 -2.0546 -0.9497 3199699 SMP2_000229 CC(C)Nc1cccnc1N2CCN(CC2)C(=O)c3cc4cc(O)ccc4[nH]3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K13 compound treatment 112040.0 -61200.0 -1.9 130080.0 -25300.0 -0.66 -1.8059 -0.8995 2709 SMP2_000230 Cc1ncc(CO)c(CO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K14 compound treatment 13560.0 -160000.0 -4.95 13840.0 -142000.0 -3.68 -6.0992 -0.9893 3076498 SMP2_000231 CC1CC2OC2/C=C\C=C/C(=O)Cc3c(Cl)c(O)cc(O)c3C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K15 compound treatment 132880.0 -40400.0 -1.25 141160.0 -14200.0 -0.37 -1.1458 -0.8782 3076544 SMP2_000232 CCN(CC)CCCC(C)Nc1nc(C)cc(Nc2ccc3nc(C)cc(N)c3c2)n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K16 compound treatment 131040.0 -42200.0 -1.31 181160.0 25800.0 0.67 -0.4512 -0.3069 633 SMP2_000233 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K17 compound treatment 14280.0 -159000.0 -4.93 20840.0 -135000.0 -3.5 -5.9548 -0.9859 3199700 SMP2_000234 CC1OC2OC3[C@@H](O)[C@@H](O)CO[C@H]3OC(=O)[C@@]45CCC(C)(C)C[C@H]5C6=CC[C@@H]7[C@@]8(C)C[C@H](O)[C@H](O[C@@H]9OC(CO)[C@@H](O)[C@H](O)C9O[C@@H]%10OC[C@@H](OC(=O)C[C@](C)(O)CC(=O)O[C@@H]1C(O[C@@H]%11OC[C@@H](O)[C@H](O)C%11O)[C@@H]2O)C(O)C%10O)[C@@](C)(CO)[C@@H]8CC[C@@]7(C)[C@]6(C)CC4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K18 compound treatment 139600.0 -33700.0 -1.04 136240.0 -19100.0 -0.5 -1.0889 -0.9424 3076548 SMP2_000235 NC1N=CC(=N1)[C@H]2[C@H](CNC(=O)c3cc(Br)c[nH]3)[C@@H](CNC(=O)c4cc(Br)c[nH]4)[C@@H]2C5=NC(N)N=C5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K19 compound treatment 119440.0 -53800.0 -1.67 130400.0 -25000.0 -0.65 -1.6379 -0.9153 3076550 SMP2_000236 CCCCC[C@H](O)[C@H](SCC(N)C(=O)O)/C=C/C=C/C=C\C/C=C\CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K20 compound treatment 31320.0 -142000.0 -4.4 41240.0 -114000.0 -2.97 -5.2067 -0.9816 3199701 SMP2_000237 CO[C@@H]1C[C@H](C)O[C@@H](CC[C@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)/C=C\C(=C/C[C@@H](O)C[C@@H]3CCC[C@@H](C[C@H](OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@H](C)[C@H](OC(=O)/C=C\C(=C/C[C@@H](O)C[C@@H]4CCC[C@@H](CC(OC)[C@@H](C)[C@@H](O)C[C@@H](O)[C@@H]2C)O4)\C)[C@@H](C)[C@@H](O)[C@@H](C)CC[C@H]5C[C@@H](C[C@H](C)O5)OC)O3)\C)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K21 compound treatment 90920.0 -82300.0 -2.55 100160.0 -55200.0 -1.43 -2.8183 -0.9629 3076553 SMP2_000238 CC(C)CCC[C@@H](C)[C@H]1C[C@H](O)C2=C3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K22 compound treatment 8280.0 -165000.0 -5.11 9200.0 -146000.0 -3.8 -6.3001 -0.9893 2329 SMP2_000239 C[C@@H]1C[C@@]2(OC3(Cc4ccccc4)O[C@@H]2[C@@H]5C=C(COC(=O)Cc6ccc(O)cc6)C[C@@]7(O)[C@@H](C=C(C)C7=O)[C@@]15O3)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K23 compound treatment 109640.0 -63600.0 -1.97 106640.0 -48700.0 -1.27 -2.2891 -0.9771 1000035 SMP2_000240 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 K24 compound treatment 121920.0 -51300.0 -1.59 145200.0 -10200.0 -0.26 -1.3117 -0.8133 1100080 SMP2_000241 OCC1OC(C(O)C1O)n2cccnc2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L01 mock treatment 170600.0 -2670.0 -0.08 133360.0 -22000.0 -0.57 -0.4626 -0.8011 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L02 mock treatment 155720.0 -17500.0 -0.54 147880.0 -7480.0 -0.19 -0.5219 -0.9038 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L03 compound treatment 141840.0 -31400.0 -0.97 142480.0 -12900.0 -0.33 -0.9252 -0.8985 155 SMP2_000242 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L04 compound treatment 131040.0 -42200.0 -1.31 171800.0 16400.0 0.43 -0.6231 -0.4527 410 SMP2_000243 CC(=N)NCc1cccc(CN)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L05 compound treatment 134960.0 -38300.0 -1.19 117440.0 -37900.0 -0.99 -1.536 -0.9957 1000029 SMP2_000244 CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]cn1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4)C(C)C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L06 compound treatment 119720.0 -53500.0 -1.66 113600.0 -41800.0 -1.09 -1.9404 -0.9788 3199703 SMP2_000245 CCC1OC2(C[C@@H]3CC(C/C=C(/C)\C(O[C@@H]4C[C@@H](C)C(O[C@H]5C[C@H](OC)C(O)[C@H](C)O5)[C@H](C4)OC)C(C)\C=C/C=C\6/COC7C6[C@@H](C=C(C)[C@H]7O)C(=O)O3)O2)C=CC1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L07 compound treatment 88040.0 -85200.0 -2.64 94000.0 -61400.0 -1.59 -2.9946 -0.9708 3076615 SMP2_000246 COC1/C=C\C=C(\C)/Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)CC(OC(=O)C(C)C)C3(C)OC3C(C)C4CC1(O)NC(=O)O4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L08 compound treatment 8160.0 -165000.0 -5.12 9200.0 -146000.0 -3.8 -6.3027 -0.9892 3199793 SMP2_000247 CCN1C[C@]2(COC)CCC(OC)[C@]3(C4C[C@@]5(O)[C@H](OC(=O)c6ccc(OC)cc6)C4[C@](C[C@H]5OC)(OC(=O)C)[C@H]7[C@H](OC)C32)[C@@H]71 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L09 compound treatment 16240.0 -157000.0 -4.87 18520.0 -137000.0 -3.56 -5.9545 -0.9881 1983 SMP2_000248 CC(C)c1cc2C3CC4C(C)(C)CCCC4(C(=O)O3)c2c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L10 compound treatment 115680.0 -57600.0 -1.78 136960.0 -18400.0 -0.48 -1.5998 -0.866 3199794 SMP2_000249 C[C@@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC[C@@]32C)[C@]45O[C@@H]5[C@H](OC(=O)C)[C@@H](C14)c6ccc(=O)oc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L11 compound treatment 45240.0 -128000.0 -3.97 44400.0 -111000.0 -2.88 -4.8436 -0.9877 3199795 SMP2_000250 CC1C2C(Cc3ccccc3)NC(=O)C24C(/C=C\CC(C)CC(C)(O)/C=C\C4O)C(O)C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L12 compound treatment 50000.0 -123000.0 -3.82 47880.0 -107000.0 -2.79 -4.6754 -0.9882 964 SMP2_000251 CN(C)N=Nc1[nH]cnc1C(=O)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L13 compound treatment 9760.0 -164000.0 -5.07 11320.0 -144000.0 -3.74 -6.2287 -0.9889 3076672 SMP2_000252 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)C(O)C2O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L14 compound treatment 160240.0 -13000.0 -0.4 180640.0 25300.0 0.66 0.179 0.2322 1001931 SMP2_000253 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L15 compound treatment 107400.0 -65900.0 -2.04 159160.0 3800.0 0.1 -1.3733 -0.6721 831956 SMP2_000254 COc1c(O)ccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L16 compound treatment 105320.0 -67900.0 -2.11 110680.0 -44700.0 -1.16 -2.3096 -0.9606 604 SMP2_000255 Oc1c(Br)cc(/C=C\2/C3C=C(I)C=CC3NC2=O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L17 compound treatment 125640.0 -47600.0 -1.48 112440.0 -42900.0 -1.12 -1.832 -0.9905 3199797 SMP2_000256 C[C@@]1([C@H]2[C@H](C(=O)O)[C@]3(CC4CC[C@H]3[C@@]52CC[C@@H]1O)CC4=C)C(=O)O5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L18 compound treatment 9840.0 -163000.0 -5.06 10440.0 -145000.0 -3.77 -6.2431 -0.9894 604 SMP2_000257 Oc1c(Br)cc(/C=C\2/C3C=C(I)C=CC3NC2=O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L19 compound treatment 130680.0 -42600.0 -1.32 128840.0 -26500.0 -0.69 -1.4203 -0.9541 97 SMP2_000258 CCCCC/C=C\C[C@@H]1O[C@H]1\C=C\C(O)C/C=C\CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L20 compound treatment 116320.0 -56900.0 -1.76 137640.0 -17700.0 -0.46 -1.5732 -0.8627 3199798 SMP2_000259 CC1CC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L21 compound treatment 86720.0 -86500.0 -2.68 92520.0 -62800.0 -1.63 -3.0507 -0.9717 2108 SMP2_000260 COc1cc2C/C(=C\c3cc(C)c(O)c(C)c3)/C(=O)c2c(N)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L22 compound treatment 98440.0 -74800.0 -2.32 99640.0 -55700.0 -1.45 -2.6631 -0.9743 440 SMP2_000261 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L23 compound treatment 138280.0 -35000.0 -1.08 124760.0 -30600.0 -0.8 -1.3288 -0.9884 1201 SMP2_000262 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 L24 compound treatment 109080.0 -64200.0 -1.99 66560.0 -88800.0 -2.31 -3.0378 -0.9973 648 SMP2_000263 Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M01 mock treatment 160440.0 -12800.0 -0.4 146360.0 -9000.0 -0.23 -0.4464 -0.968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M02 mock treatment 186120.0 12900.0 0.4 141000.0 -14400.0 -0.37 0.0178 0.0326 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M03 compound treatment 64560.0 -109000.0 -3.37 105800.0 -49600.0 -1.29 -3.2923 -0.913 549 SMP2_000264 Nc1ncnc2nc(cc(c3cccc(Br)c3)c12)c4ccc(nc4)N5CCOCC5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M04 compound treatment 97160.0 -76100.0 -2.36 157480.0 2120.0 0.06 -1.6285 -0.6904 1092656 SMP2_000265 CC1OC(CC(=O)O)CC2=C1C(=O)c3c(O)cccc3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M05 compound treatment 124000.0 -49300.0 -1.53 113400.0 -42000.0 -1.09 -1.8503 -0.9864 1000067 SMP2_000266 NC(C(=O)NC1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M06 compound treatment 7360.0 -166000.0 -5.14 9560.0 -146000.0 -3.79 -6.3136 -0.9887 535 SMP2_000267 ONC(=O)CCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M07 compound treatment 32920.0 -140000.0 -4.35 50680.0 -105000.0 -2.72 -4.9982 -0.9745 3177114 SMP2_000268 CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M08 compound treatment 122840.0 -50400.0 -1.56 126280.0 -29100.0 -0.76 -1.6391 -0.9444 241 SMP2_000269 CC[C@@H](C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NCC(N)CS 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M09 compound treatment 120400.0 -52900.0 -1.64 114840.0 -40500.0 -1.05 -1.9027 -0.9772 3076808 SMP2_000270 CC1(C)[C@H]2C[C@@H]1C(=C)[C@H](O)C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M10 compound treatment 99520.0 -73700.0 -2.29 143840.0 -11500.0 -0.3 -1.8274 -0.7929 220 SMP2_000271 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M11 compound treatment 9320.0 -164000.0 -5.08 10280.0 -145000.0 -3.77 -6.2575 -0.9892 1579 SMP2_000272 CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M12 compound treatment 124640.0 -48600.0 -1.51 123440.0 -31900.0 -0.83 -1.6518 -0.9604 284 SMP2_000273 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M13 compound treatment 134520.0 -38700.0 -1.2 128680.0 -26700.0 -0.69 -1.3391 -0.9659 3076815 SMP2_000274 CC(O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M14 compound treatment 120200.0 -53100.0 -1.64 155760.0 401.0 0.01 -1.1553 -0.7026 1102317 SMP2_000275 COc1ccc(cc1)C23Oc4cc(OC)cc(OC)c4C3(O)C(O)C(C2c5ccccc5)C(=O)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M15 compound treatment 130400.0 -42900.0 -1.33 141800.0 -13600.0 -0.35 -1.1883 -0.8648 1907751 SMP2_000276 CN/C(=N\c1ccc(cc1)C2=NNC(=O)CC2C)/NC#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M16 compound treatment 44120.0 -129000.0 -4.0 34560.0 -121000.0 -3.14 -5.0489 -0.9928 536 SMP2_000277 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M17 compound treatment 6720.0 -167000.0 -5.16 7800.0 -148000.0 -3.83 -6.36 -0.9893 3076873 SMP2_000278 COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)/C=C/c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M18 compound treatment 35400.0 -138000.0 -4.27 33160.0 -122000.0 -3.18 -5.2657 -0.9893 536 SMP2_000279 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M19 compound treatment 47280.0 -126000.0 -3.9 65000.0 -90400.0 -2.35 -4.4204 -0.9704 3199800 SMP2_000280 CC(C)CCC[C@@H](C)[C@H]1CC(=O)[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M20 compound treatment 106040.0 -67200.0 -2.08 130000.0 -25400.0 -0.66 -1.9388 -0.8874 3199801 SMP2_000281 CO[C@@H]([C@H](O)CC(=O)[C@@H](C)[C@@H](O)CC[C@@H](C)C1O[C@]2(CC[C@@H](C)C(CC[C@H](C)C(=O)C)O2)CC[C@@H]1C)[C@H](OC(=O)C[C@@H](O)C3=C(C)C(=O)OC3=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M21 compound treatment 134200.0 -39100.0 -1.21 184280.0 28900.0 0.75 -0.3246 -0.2278 257 SMP2_000282 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M22 compound treatment 119760.0 -53500.0 -1.66 149280.0 -6080.0 -0.16 -1.284 -0.771 3076883 SMP2_000283 CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(=O)N)NC(=O)C(CCC(=O)N)NC1=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M23 compound treatment 160960.0 -12300.0 -0.38 137480.0 -17900.0 -0.46 -0.5981 -0.9952 2059 SMP2_000284 CC(C)CC(N)C(O)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 M24 compound treatment 12040.0 -161000.0 -5.0 16440.0 -139000.0 -3.61 -6.0847 -0.9873 2350 SMP2_000285 Cc1c(C)c2OC(C)(CN3CCN(CC3)c4cc(nc(n4)N5CCCC5)N6CCCC6)CCc2c(C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N01 mock treatment 167840.0 -5430.0 -0.17 183120.0 27800.0 0.72 0.3911 0.5281 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N02 mock treatment 183120.0 9850.0 0.31 146320.0 -9040.0 -0.23 0.0498 0.1292 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N03 compound treatment 138720.0 -34500.0 -1.07 147000.0 -8360.0 -0.22 -0.9105 -0.8336 3076955 SMP2_000286 CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)CC23C(=O)O[C@@H]4OC(=O)[C@H](O)C413 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N04 compound treatment 88240.0 -85000.0 -2.63 107360.0 -48000.0 -1.25 -2.7448 -0.9417 907302 SMP2_000287 CN1CC[C@]2(C)C1N(C)c3ccc(O)cc32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N05 compound treatment 139560.0 -33700.0 -1.04 130600.0 -24800.0 -0.64 -1.1934 -0.9729 3199802 SMP2_000288 CSC(=S)NCc1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N06 compound treatment 123600.0 -49700.0 -1.54 147320.0 -8040.0 -0.21 -1.2359 -0.7958 398 SMP2_000289 OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N07 compound treatment 34400.0 -139000.0 -4.3 40880.0 -114000.0 -2.97 -5.1458 -0.9837 1975 SMP2_000290 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1c5ccc(=O)oc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N08 compound treatment 75920.0 -97300.0 -3.02 108840.0 -46500.0 -1.21 -2.9875 -0.9194 1026746 SMP2_000291 OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N09 compound treatment 26600.0 -147000.0 -4.54 37160.0 -118000.0 -3.07 -5.385 -0.9818 810 SMP2_000292 CCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N10 compound treatment 43520.0 -130000.0 -4.02 58160.0 -97200.0 -2.53 -4.6285 -0.9749 3176068 SMP2_000293 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N11 compound treatment 109840.0 -63400.0 -1.97 94560.0 -60800.0 -1.58 -2.5067 -0.9941 2018 SMP2_000294 NC1=NC(=O)/C(=C/2\CCNC(=O)c3[nH]ccc23)/N1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N12 compound treatment 104240.0 -69000.0 -2.14 113720.0 -41600.0 -1.08 -2.2774 -0.9501 1090 SMP2_000295 CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N13 compound treatment 120160.0 -53100.0 -1.65 127360.0 -28000.0 -0.73 -1.678 -0.9326 3199804 SMP2_000296 CC(C)CC(NC(=O)C(Cc1ccc(OP(O)(O)O)cc1)NC(=O)C2CCCN2C(=O)C)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N14 compound treatment 6360.0 -167000.0 -5.17 8080.0 -147000.0 -3.83 -6.3627 -0.989 1000674 SMP2_000297 COc1cccc2C(=O)c3c(O)c4CC(O)(CC(OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N15 compound treatment 6240.0 -167000.0 -5.18 7840.0 -148000.0 -3.83 -6.3698 -0.9891 1084811 SMP2_000298 Cc1c2[nH]c3ccc(O)cc3c2c(C)c4cnccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N16 compound treatment 84000.0 -89300.0 -2.77 122160.0 -33200.0 -0.86 -2.5658 -0.8856 3077040 SMP2_000299 CC(C)[C@H]1CN2CCC[C@H]2[C@@]3(O)O[C@](CC(=O)[C@H]4CN(C)[C@@H]5Cc6c[nH]c7cccc(C5=C4)c67)(C(C)C)C(=O)N13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N17 compound treatment 127520.0 -45700.0 -1.42 139360.0 -16000.0 -0.42 -1.2963 -0.8775 1108916 SMP2_000300 NCCCCC(NC(=O)C(Cc1c[nH]cn1)NC(=O)CN)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N18 compound treatment 12960.0 -160000.0 -4.97 20360.0 -135000.0 -3.51 -5.9925 -0.9855 3177114 SMP2_000301 CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N19 compound treatment 127080.0 -46200.0 -1.43 114720.0 -40600.0 -1.06 -1.7586 -0.9888 3076041 SMP2_000302 COc1cc(/C=C/c2cccc[n+]2C)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N20 compound treatment 125320.0 -47900.0 -1.49 119680.0 -35700.0 -0.93 -1.706 -0.9742 1734 SMP2_000303 Nc1nnc(c(N)n1)c2cccc(Cl)c2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N21 compound treatment 124120.0 -49100.0 -1.52 153800.0 -1560.0 -0.04 -1.1054 -0.7257 3076048 SMP2_000304 OC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N22 compound treatment 13600.0 -160000.0 -4.95 17680.0 -138000.0 -3.58 -6.0277 -0.9873 1000089 SMP2_000305 COC1C(C)OC(OC2CC(C)(O)C(C(=O)OC)c3cc4C(=O)c5c6OC7OC(C)(C(O)C(C7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)C(OC)C1(C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N23 compound treatment 38560.0 -135000.0 -4.17 33120.0 -122000.0 -3.18 -5.1972 -0.9909 628 SMP2_000306 Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 N24 compound treatment 175840.0 2570.0 0.08 159800.0 4440.0 0.12 0.1379 0.9836 1273 SMP2_000307 C[C@@]12CC(=O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O01 mock treatment 163360.0 -9910.0 -0.31 164440.0 9080.0 0.24 -0.0502 -0.1297 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O02 mock treatment 172040.0 -1230.0 -0.04 118480.0 -36900.0 -0.96 -0.7045 -0.7346 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O03 compound treatment 114040.0 -59200.0 -1.84 126600.0 -28800.0 -0.75 -1.826 -0.9216 1059696 SMP2_000308 CC1CCC2(C)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O04 compound treatment 126520.0 -46700.0 -1.45 109360.0 -46000.0 -1.2 -1.8693 -0.9954 988 SMP2_000309 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O05 compound treatment 133840.0 -39400.0 -1.22 191160.0 35800.0 0.93 -0.2061 -0.1342 413 SMP2_000310 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O06 compound treatment 115120.0 -58100.0 -1.8 121760.0 -33600.0 -0.87 -1.8913 -0.9447 3199805 SMP2_000311 NC(=O)OC[C@H]1[C@@H]2NC(=N)N[C@]23N(CCC3(O)O)C(=N)N1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O07 compound treatment 13880.0 -159000.0 -4.94 28680.0 -127000.0 -3.29 -5.8195 -0.9806 2081802 SMP2_000312 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O08 compound treatment 106080.0 -67200.0 -2.08 107640.0 -47700.0 -1.24 -2.3488 -0.9693 1080649 SMP2_000313 CC1(CC2(O)OC3O1)C4(CC2C34COC(=O)c5ccccc5)OC6OC(CO)C(O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O09 compound treatment 68560.0 -105000.0 -3.24 96240.0 -59100.0 -1.54 -3.3803 -0.9417 3076119 SMP2_000314 CNc1ccc2ccccc2c1N=Nc3ccc(N=Nc4ccccc4)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O10 compound treatment 125160.0 -48100.0 -1.49 111640.0 -43700.0 -1.14 -1.8573 -0.991 1072985 SMP2_000315 CC1C(O)C2(O)C(C3C=C(CO)CC4(O)C(C=C(C)C4=O)C13O)C2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O11 compound treatment 120480.0 -52800.0 -1.64 111880.0 -43500.0 -1.13 -1.9554 -0.9837 3076122 SMP2_000316 CC(=C[C@H](C=C)C(C)(C)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O12 compound treatment 47480.0 -126000.0 -3.9 47280.0 -108000.0 -2.81 -4.7416 -0.9871 3001166 SMP2_000317 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O13 compound treatment 6960.0 -166000.0 -5.15 7760.0 -148000.0 -3.84 -6.3555 -0.9894 189 SMP2_000318 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O14 compound treatment 104440.0 -68800.0 -2.13 114800.0 -40600.0 -1.05 -2.2532 -0.9472 3199895 SMP2_000319 CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)O)NC(=O)C3CCCN3C(=O)C(CC(=O)N)NC(=O)C4CCCN4C(=O)C(N)CCCCN)C(=O)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O15 compound treatment 5920.0 -167000.0 -5.19 7000.0 -148000.0 -3.85 -6.3922 -0.9893 2305 SMP2_000320 COC1=C(N)C(=O)c2nc(ccc2C1=O)c3nc(C(=O)O)c(C)c(c3N)c4ccc(OC)c(OC)c4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O16 compound treatment 112720.0 -60500.0 -1.88 112240.0 -43100.0 -1.12 -2.1188 -0.9696 3076126 SMP2_000321 Nc1ncnc2n([C@@H]3OC4COP(O)(S)O[C@@H]4C3O)c(nc12)N5CCCCC5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O17 compound treatment 35520.0 -138000.0 -4.27 51520.0 -104000.0 -2.7 -4.9258 -0.9755 2080871 SMP2_000322 CC1=C(O)C(=O)[C@@H]2O[C@@H]2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O18 compound treatment 91840.0 -81400.0 -2.52 114160.0 -41200.0 -1.07 -2.541 -0.9271 3076175 SMP2_000323 COc1cc(ccc1O)[C@H]2Oc3cc(ccc3O[C@@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O19 compound treatment 10320.0 -163000.0 -5.05 11640.0 -144000.0 -3.73 -6.2106 -0.989 3199896 SMP2_000324 CC(C)CCC[C@@H](C)[C@H]1CC(=O)C2=C3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O20 compound treatment 137360.0 -35900.0 -1.11 123600.0 -31800.0 -0.83 -1.3702 -0.9892 3076177 SMP2_000325 COc1cc(ccc1O)c2cc(=O)c3c(O)cc(OC4OC(CO)C(O)C(O)C4OS(=O)(=O)O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O21 compound treatment 47400.0 -126000.0 -3.9 39440.0 -116000.0 -3.01 -4.8874 -0.9918 2119025 SMP2_000326 Nc1nc(S)c2nc[nH]c2n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O22 compound treatment 12520.0 -161000.0 -4.98 12520.0 -143000.0 -3.71 -6.1462 -0.9895 2081802 SMP2_000327 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O23 compound treatment 13240.0 -160000.0 -4.96 5480.0 -150000.0 -3.89 -6.2598 -0.9929 316 SMP2_000328 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 O24 compound treatment 15200.0 -158000.0 -4.9 42680.0 -113000.0 -2.93 -5.5334 -0.9697 1004963 SMP2_000329 CC1CCC2(CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P01 mock treatment 133000.0 -40300.0 -1.25 113680.0 -41700.0 -1.08 -1.648 -0.9975 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P02 mock treatment 151200.0 -22100.0 -0.68 138200.0 -17200.0 -0.45 -0.7988 -0.9785 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P03 compound treatment 90000.0 -83300.0 -2.58 134880.0 -20500.0 -0.53 -2.2006 -0.8354 3199897 SMP2_000330 CS[C@]12CC3=CC=CC(O)[C@H]3N2C(=O)[C@@](CO)(SC)N(C)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P04 compound treatment 122760.0 -50500.0 -1.56 115840.0 -39500.0 -1.03 -1.8327 -0.9791 2060488 SMP2_000331 CC(=CCC[C@@](C)(O)C=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P05 compound treatment 104200.0 -69100.0 -2.14 105240.0 -50100.0 -1.3 -2.4341 -0.9716 1968 SMP2_000332 C[C@@H]1CC2OC3CC4OC(=O)C=C(C)C4O[C@@]3(C)CC2OC5CC[C@@]6(C)O[C@@]7(C)CC8OC9CC%10O[C@@]%11(C)[C@@H](O)C[C@@H](CC(=C)C=O)OC%11CC%10OC9C=CC[C@]8(C)OC7CC6OC15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P06 compound treatment 120800.0 -52500.0 -1.63 101840.0 -53500.0 -1.39 -2.1328 -0.997 1000053 SMP2_000333 OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P07 compound treatment 5640.0 -168000.0 -5.19 11520.0 -144000.0 -3.74 -6.3153 -0.987 1977 SMP2_000334 CC12CCc3occc3[C@H]2CCC4(CC5CC[C@H]41)C[C@]5(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P08 compound treatment 112520.0 -60700.0 -1.88 117920.0 -37400.0 -0.97 -2.0188 -0.9528 1693 SMP2_000335 NCCCNCCSP(=O)(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P09 compound treatment 7560.0 -166000.0 -5.13 35560.0 -120000.0 -3.11 -5.8316 -0.9712 3199899 SMP2_000336 CC[C@@H]1[C@H](O)[C@@H](C)C/C(=C\C=C/C(=C(\OC(=O)\C(=C/C(=C\[C@H](C)C1O)/C)\OC)/[C@@H](C)[C@@H](O)[C@H](C)[C@@]2(O)C[C@@H](OC3CC(O)C(OC(=O)N)C(C)O3)[C@H](C)[C@H](O2)/C=C/C)/OC)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P10 compound treatment 53320.0 -120000.0 -3.72 128360.0 -27000.0 -0.7 -3.124 -0.826 446 SMP2_000337 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P11 compound treatment 44400.0 -129000.0 -3.99 57560.0 -97800.0 -2.54 -4.6202 -0.9762 360 SMP2_000338 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P12 compound treatment 43440.0 -130000.0 -4.02 29800.0 -126000.0 -3.26 -5.1513 -0.9946 3068886 SMP2_000339 CC(C)/N=c/1\cc2n(c3ccc(Cl)cc3)c4ccccc4nc2cc1Nc5ccc(Cl)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P13 compound treatment 90480.0 -82800.0 -2.57 101360.0 -54000.0 -1.4 -2.8059 -0.9597 1817 SMP2_000340 CC(=O)O[C@@]12CO[C@H]2C[C@@H](O)[C@@]3(C)[C@H]1[C@H](OC(=O)c4ccccc4)[C@@]5(O)C[C@H](OC(=O)[C@@H](O)[C@H](NC(=O)OC(C)(C)C)c6ccccc6)C(=C([C@H](O)C3=O)C5(C)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P14 compound treatment 116520.0 -56700.0 -1.76 101160.0 -54200.0 -1.41 -2.2391 -0.9939 3076236 SMP2_000341 COc1ccc(C=Cc2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P15 compound treatment 3640.0 -170000.0 -5.26 5640.0 -150000.0 -3.89 -6.4672 -0.989 832320 SMP2_000342 CC[C@H](C)[C@H](NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)C)C(=O)N[C@@H](C(=O)C)C(=O)N[C@@H](CC(C)C)[C@@]1(O)O[C@H](C)[C@H](N[C@@]1(C)CO)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P16 compound treatment 24520.0 -149000.0 -4.61 67280.0 -88100.0 -2.29 -4.8772 -0.9478 2069 SMP2_000343 CC12CCC3C(CCC4=C(O)C(=O)CCC34C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P17 compound treatment 119200.0 -54100.0 -1.68 107440.0 -47900.0 -1.25 -2.065 -0.9893 3199902 SMP2_000344 CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(N)CO)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NC(Cc4ccccc4)C(=O)NCC(=O)NC(Cc5ccccc5)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P18 compound treatment 6720.0 -167000.0 -5.16 6560.0 -149000.0 -3.87 -6.3828 -0.9899 2100 SMP2_000345 COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@H]2c3cc4OCOc4cc3CCN5CCC[C@]25C=C1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P19 compound treatment 101160.0 -72100.0 -2.23 118560.0 -36800.0 -0.96 -2.2559 -0.9283 613 SMP2_000346 Oc1cc(/C=C/c2ccc(O)c(O)c2)oc(=O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P20 compound treatment 109760.0 -63500.0 -1.97 112200.0 -43200.0 -1.12 -2.1844 -0.9645 3076242 SMP2_000347 CC1(C)O[C@H]2CC(=O)OC[C@]23[C@H]4CC[C@@](C)([C@@H](OC5OC(CO)C(O)C(O)C5O)c6ccoc6)[C@@]7(O[C@@H]7C(=O)O)[C@]4(C)C(=O)C[C@]13C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P21 compound treatment 59200.0 -114000.0 -3.53 53760.0 -102000.0 -2.64 -4.3658 -0.9897 3199903 SMP2_000348 C/C=C(/C)\C(=O)O[C@H]1C(=C[C@]2([C@H](C)C[C@H]3[C@@H](C3(C)C)[C@]4(C)C=C(CO)[C@@H](O)[C@@]12O)C4=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P22 compound treatment 145240.0 -28000.0 -0.87 139920.0 -15400.0 -0.4 -0.8977 -0.9384 1048361 SMP2_000349 c1ccc2c(c1)[nH]c3cnccc32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P23 compound treatment 155800.0 -17500.0 -0.54 137320.0 -18000.0 -0.47 -0.7141 -0.9974 832145 SMP2_000350 OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H]2NC(=O)C(=O)N21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2099 P24 compound treatment 53920.0 -119000.0 -3.7 53520.0 -102000.0 -2.65 -4.4859 -0.9865 2260 SMP2_000351 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(CO)c8c1c2c(c34)c(c65)c78 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A01 mock treatment 93080.0 -33000.0 -1.02 84440.0 -40100.0 -1.04 -1.4591 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A02 mock treatment 124040.0 -2040.0 -0.06 147080.0 22600.0 0.59 0.3701 0.6271 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A03 mock treatment 137960.0 11900.0 0.37 168920.0 44400.0 1.15 1.0764 0.8885 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A04 mock treatment 127720.0 1640.0 0.05 185600.0 61100.0 1.59 1.1585 0.7293 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A05 mock treatment 137320.0 11200.0 0.35 210560.0 86100.0 2.24 1.8274 0.8075 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A06 mock treatment 139560.0 13500.0 0.42 196720.0 72200.0 1.88 1.6222 0.8438 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A07 mock treatment 79160.0 -46900.0 -1.45 209480.0 85000.0 2.21 0.5333 0.2017 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A08 mock treatment 119840.0 -6240.0 -0.19 198720.0 74200.0 1.93 1.2269 0.633 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A09 mock treatment 94960.0 -31100.0 -0.96 220680.0 96200.0 2.5 1.0852 0.4051 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A10 mock treatment 98160.0 -27900.0 -0.87 203480.0 79000.0 2.05 0.8393 0.3769 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A11 mock treatment 122400.0 -3680.0 -0.11 216120.0 91600.0 2.38 1.6026 0.6724 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A12 mock treatment 133640.0 7560.0 0.23 204200.0 79700.0 2.07 1.6299 0.7821 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A13 mock treatment 153400.0 27300.0 0.85 217800.0 93300.0 2.42 2.3127 0.9007 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A14 mock treatment 128240.0 2160.0 0.07 222120.0 97600.0 2.54 1.8408 0.7255 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A15 mock treatment 140120.0 14000.0 0.43 214320.0 89800.0 2.33 1.9578 0.8247 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A16 mock treatment 125080.0 -1000.0 -0.03 227640.0 103000.0 2.68 1.873 0.6988 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A17 mock treatment 138200.0 12100.0 0.38 222160.0 97700.0 2.54 2.0598 0.803 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A18 mock treatment 137600.0 11500.0 0.36 204160.0 79700.0 2.07 1.7159 0.8169 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A19 mock treatment 150360.0 24300.0 0.75 226600.0 102000.0 2.65 2.4078 0.8732 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A20 mock treatment 163040.0 37000.0 1.15 213520.0 89000.0 2.31 2.4453 0.9474 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A21 mock treatment 128120.0 2040.0 0.06 179840.0 55300.0 1.44 1.0614 0.7374 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A22 mock treatment 149240.0 23200.0 0.72 175040.0 50500.0 1.31 1.4359 0.9596 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A23 mock treatment 120720.0 -5360.0 -0.17 141320.0 16800.0 0.44 0.1916 0.4096 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 A24 mock treatment 100360.0 -25700.0 -0.8 91120.0 -33400.0 -0.87 -1.1768 -0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B01 mock treatment 133920.0 7840.0 0.24 149320.0 24800.0 0.64 0.6277 0.9109 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B02 mock treatment 156480.0 30400.0 0.94 202960.0 78500.0 2.04 2.1075 0.9385 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B03 compound treatment 147160.0 21100.0 0.65 164920.0 40400.0 1.05 1.2044 0.9739 2277 HSCI1_000001 CCc1nc([nH]c1c2ccncc2)c3ccc(OC)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B04 compound treatment 12080.0 -114000.0 -3.53 11760.0 -113000.0 -2.93 -4.569 -0.9957 656 HSCI1_000002 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B05 compound treatment 112960.0 -13100.0 -0.41 119840.0 -4660.0 -0.12 -0.3731 -0.8794 2114187 HSCI1_000003 CCOC(=O)c1cccc(NC(=O)CBr)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B06 compound treatment 10280.0 -116000.0 -3.59 10320.0 -114000.0 -2.97 -4.6349 -0.9955 1362420 HSCI1_000004 Oc1c(I)cc(Cl)cc1C(=O)Nc2cc(ccc2Cl)S(=O)(=O)c3ccc(Cl)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B07 compound treatment 63400.0 -62700.0 -1.94 20240.0 -104000.0 -2.71 -3.2888 -0.9867 3175973 HSCI1_000005 COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B08 compound treatment 6240.0 -120000.0 -3.71 9880.0 -115000.0 -2.98 -4.7315 -0.994 3175974 HSCI1_000006 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1CCC(O)C(O)C1O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B09 compound treatment 42560.0 -83500.0 -2.59 38680.0 -85800.0 -2.23 -3.4066 -0.9972 9 HSCI1_000007 [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B10 compound treatment 76760.0 -49300.0 -1.53 130960.0 6460.0 0.17 -0.9619 -0.6256 571 HSCI1_000008 CCCCCCCCCCCCCCCCCCOC[C@H](COC(=O)OC1C(O)C(O)C(O)C(CO)C1O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B11 mock treatment 133640.0 7560.0 0.23 133040.0 8540.0 0.22 0.3225 0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B12 mock treatment 147040.0 21000.0 0.65 151960.0 27500.0 0.71 0.9637 0.9989 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B13 mock treatment 138080.0 12000.0 0.37 197440.0 72900.0 1.9 1.603 0.83 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B14 mock treatment 152080.0 26000.0 0.81 195960.0 71500.0 1.86 1.8825 0.9301 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B15 compound treatment 120000.0 -6080.0 -0.19 176880.0 52400.0 1.36 0.8291 0.6034 3055039 HSCI1_000009 Cn1cnc2nc(NCCO)nc(NCc3ccccc3)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B16 compound treatment 7840.0 -118000.0 -3.66 12480.0 -112000.0 -2.91 -4.6487 -0.9935 3175975 HSCI1_000010 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1C(O)C(O)C(O)CC1OC)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B17 compound treatment 7040.0 -119000.0 -3.69 41160.0 -83300.0 -2.17 -4.1393 -0.9678 3055043 HSCI1_000011 CCCCCCCCCCCCCCC[C@@H](O)[C@H](N)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B18 compound treatment 6400.0 -120000.0 -3.71 10440.0 -114000.0 -2.96 -4.7177 -0.9938 2326 HSCI1_000012 CCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B19 compound treatment 82760.0 -43300.0 -1.34 164120.0 39600.0 1.03 -0.2212 -0.1308 2026 HSCI1_000013 CCCCCCCCCCNc1cc(CO)c2cc[nH]c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B20 compound treatment 16040.0 -110000.0 -3.41 20240.0 -104000.0 -2.71 -4.3265 -0.9935 193 HSCI1_000014 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B21 compound treatment 64440.0 -61600.0 -1.91 94320.0 -30200.0 -0.78 -1.905 -0.9227 3055048 HSCI1_000015 Nc1nc(Cl)nc2n(cnc12)C3OC(CO)[C@H](O)[C@H]3F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B22 compound treatment 6520.0 -120000.0 -3.7 8360.0 -116000.0 -3.02 -4.7533 -0.9948 3175977 HSCI1_000016 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@]41OC(=O)CCCCCCCCC)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B23 mock treatment 122400.0 -3680.0 -0.11 182360.0 57900.0 1.5 0.9824 0.6515 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 B24 mock treatment 111880.0 -14200.0 -0.44 142800.0 18300.0 0.48 0.0251 0.0387 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C01 mock treatment 119200.0 -6880.0 -0.21 161960.0 37500.0 0.97 0.5375 0.5393 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C02 mock treatment 153400.0 27300.0 0.85 201000.0 76500.0 1.99 2.004 0.9276 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C03 compound treatment 167520.0 41400.0 1.28 144520.0 20000.0 0.52 1.2757 0.9209 2257 HSCI1_000017 COc1ccc(cc1)C(=O)CBr 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C04 compound treatment 137520.0 11400.0 0.35 110160.0 -14300.0 -0.37 -0.0129 -0.025 561 HSCI1_000018 C[C@@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C05 compound treatment 158000.0 31900.0 0.99 126960.0 2460.0 0.06 0.7445 0.7513 2256 HSCI1_000019 Oc1ccc(cc1)C(=O)CBr 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C06 compound treatment 105040.0 -21000.0 -0.65 101000.0 -23500.0 -0.61 -0.8928 -0.9995 1000099 HSCI1_000020 C[C@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C07 compound treatment 137560.0 11500.0 0.36 129680.0 5180.0 0.13 0.3466 0.9117 2258 HSCI1_000021 OC(=O)COc1ccc(cc1)C(=O)CBr 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C08 compound treatment 72200.0 -53900.0 -1.67 125600.0 1100.0 0.03 -1.1603 -0.6949 2227 HSCI1_000022 CCCCCCCCCCCCCCCC(=O)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C09 compound treatment 7520.0 -119000.0 -3.67 10800.0 -114000.0 -2.95 -4.6866 -0.9942 2147 HSCI1_000023 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(=O)(F)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C10 compound treatment 80480.0 -45600.0 -1.41 99200.0 -25300.0 -0.66 -1.4639 -0.9394 617 HSCI1_000024 COc1cc(OC)c(/C=C\2/C(=O)Nc3ccccc23)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C11 mock treatment 130000.0 3920.0 0.12 111720.0 -12800.0 -0.33 -0.149 -0.4215 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C12 mock treatment 146480.0 20400.0 0.63 136520.0 12000.0 0.31 0.6677 0.9472 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C13 mock treatment 146480.0 20400.0 0.63 138800.0 14300.0 0.37 0.7096 0.968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C14 mock treatment 122840.0 -3240.0 -0.1 129000.0 4500.0 0.12 0.0117 0.0755 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C15 mock treatment 132720.0 6640.0 0.21 143240.0 18700.0 0.49 0.4897 0.9264 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C16 mock treatment 115320.0 -10800.0 -0.33 173440.0 48900.0 1.27 0.6634 0.5046 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C17 compound treatment 113800.0 -12300.0 -0.38 170320.0 45800.0 1.19 0.5727 0.4582 3055108 HSCI1_000025 CSCC1OC([C@@H](O)[C@H]1O)n2ccc3c(N)ncnc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C18 compound treatment 7680.0 -118000.0 -3.67 11240.0 -113000.0 -2.94 -4.675 -0.994 3055110 HSCI1_000026 ClCC(=O)c1cc(Br)c(Br)s1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C19 compound treatment 123040.0 -3040.0 -0.09 157280.0 32800.0 0.85 0.5356 0.625 2121 HSCI1_000027 Oc1ccc(cc1)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C20 compound treatment 130320.0 4240.0 0.13 203240.0 78700.0 2.05 1.5395 0.7509 1916983 HSCI1_000028 CC(C)C(N1C(=O)/C(=C/c2ccccc2)/SC1=S)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C21 compound treatment 6240.0 -120000.0 -3.71 8280.0 -116000.0 -3.02 -4.7609 -0.9947 2188 HSCI1_000029 Oc1ccc(O)c2C(=O)C(=C(Cl)C(=O)c12)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C22 compound treatment 24720.0 -101000.0 -3.14 24400.0 -100000.0 -2.6 -4.0599 -0.9956 563 HSCI1_000030 Oc1ccc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C23 compound treatment 129920.0 3840.0 0.12 147440.0 22900.0 0.6 0.5056 0.8317 1031143 HSCI1_000031 CS(=O)(=O)SCCN 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 C24 mock treatment 124920.0 -1160.0 -0.04 129000.0 4500.0 0.12 0.0572 0.4673 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D01 mock treatment 112320.0 -13800.0 -0.43 140480.0 16000.0 0.42 -0.0079 -0.0133 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D02 mock treatment 145600.0 19500.0 0.6 148160.0 23700.0 0.61 0.8623 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D03 compound treatment 46480.0 -79600.0 -2.47 41200.0 -83300.0 -2.16 -3.2745 -0.9979 551 HSCI1_000032 CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D04 compound treatment 168160.0 42100.0 1.3 156080.0 31600.0 0.82 1.5021 0.9751 3479696 HSCI1_000033 OC(=O)C(CCCCNC(=O)CNC(=O)c1cccc(c1)C(=O)NCC(=O)NCCCCC(NC(=O)OCc2ccc(cc2)C(F)(F)F)C(=O)O)NC(=O)OCc3ccc(cc3)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D05 compound treatment 115760.0 -10300.0 -0.32 104120.0 -20400.0 -0.53 -0.6006 -0.9709 674 HSCI1_000034 CCOC(=O)c1c(C)[nH]c(/C=C/2\C(=O)Nc3ccccc23)c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D06 compound treatment 9080.0 -117000.0 -3.63 9480.0 -115000.0 -2.99 -4.6767 -0.9954 146 HSCI1_000035 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D07 compound treatment 122600.0 -3480.0 -0.11 153680.0 29200.0 0.76 0.4598 0.6004 3175981 HSCI1_000036 O=c1sn(Cc2ccccc2)c(=S)n1Cc3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D08 compound treatment 67400.0 -58700.0 -1.82 90240.0 -34300.0 -0.89 -1.9151 -0.946 1000097 HSCI1_000037 Cc1c(C)c2OC(C)(COc3ccc(CC4SC(=O)NC4=O)cc3)CCc2c(C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D09 compound treatment 83520.0 -42600.0 -1.32 129480.0 4980.0 0.13 -0.841 -0.6346 628 HSCI1_000038 Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D10 compound treatment 131680.0 5600.0 0.17 112920.0 -11600.0 -0.3 -0.0901 -0.2595 3175982 HSCI1_000039 COc1ccc(Nc2nccc(NCCO)n2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D11 mock treatment 136840.0 10800.0 0.33 124040.0 -456.0 -0.01 0.2273 0.6815 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D12 mock treatment 139760.0 13700.0 0.42 115520.0 -8980.0 -0.23 0.1347 0.2785 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D13 mock treatment 141640.0 15600.0 0.48 139880.0 15400.0 0.4 0.6234 0.9957 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D14 mock treatment 131400.0 5320.0 0.16 117920.0 -6580.0 -0.17 -0.0044 -0.0184 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D15 mock treatment 129880.0 3800.0 0.12 124920.0 424.0 0.01 0.0909 0.7699 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D16 mock treatment 144560.0 18500.0 0.57 148440.0 23900.0 0.62 0.8447 0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D17 compound treatment 44280.0 -81800.0 -2.53 65720.0 -58800.0 -1.53 -2.8722 -0.9706 584 HSCI1_000040 Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D18 compound treatment 76120.0 -50000.0 -1.55 79920.0 -44600.0 -1.16 -1.9137 -0.9898 2180 HSCI1_000041 COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C(C)C)c4n2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D19 compound treatment 81280.0 -44800.0 -1.39 102000.0 -22500.0 -0.58 -1.395 -0.9261 3055161 HSCI1_000042 COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D20 compound treatment 155560.0 29500.0 0.91 163400.0 38900.0 1.01 1.3605 0.9987 2067 HSCI1_000043 CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D21 compound treatment 79920.0 -46200.0 -1.43 89520.0 -35000.0 -0.91 -1.654 -0.976 3055164 HSCI1_000044 N/C(=C(/C#N)\c1ccccc1C(F)(F)F)/Sc2ccc(N)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D22 compound treatment 134760.0 8680.0 0.27 135320.0 10800.0 0.28 0.3889 0.9997 2407 HSCI1_000045 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ncc(C)s3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D23 compound treatment 28000.0 -98100.0 -3.04 28840.0 -95700.0 -2.49 -3.9064 -0.995 550 HSCI1_000046 COC1=C(Br)[C@H](O)[C@](O)(CC#N)C=C1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 D24 mock treatment 97000.0 -29100.0 -0.9 113840.0 -10700.0 -0.28 -0.833 -0.8836 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E01 mock treatment 107880.0 -18200.0 -0.56 160760.0 36300.0 0.94 0.2674 0.2435 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E02 mock treatment 138520.0 12400.0 0.39 156160.0 31700.0 0.82 0.8542 0.9403 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E03 mock treatment 127080.0 995.0 0.03 142240.0 17700.0 0.46 0.3478 0.7527 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E04 mock treatment 122480.0 -3600.0 -0.11 135280.0 10800.0 0.28 0.1191 0.395 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E05 compound treatment 140920.0 14800.0 0.46 129800.0 5300.0 0.14 0.4225 0.8804 2294 HSCI1_000047 CC(=O)NC(C(=O)O)C(C)(C)SN=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E06 compound treatment 128560.0 2480.0 0.08 129200.0 4700.0 0.12 0.1406 0.9748 3175983 HSCI1_000048 CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCC/C=C/C/C=C/C\C=C\C\C=C\CCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E07 compound treatment 98240.0 -27800.0 -0.86 117000.0 -7500.0 -0.19 -0.7478 -0.8455 640 HSCI1_000049 O=C/1Nc2ccccc2\C1=C\c3ccc[nH]3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E08 compound treatment 136840.0 10800.0 0.33 132040.0 7540.0 0.2 0.3742 0.968 1907779 HSCI1_000050 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E09 mock treatment 123680.0 -2400.0 -0.07 130080.0 5580.0 0.15 0.0499 0.3059 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E10 mock treatment 130840.0 4760.0 0.15 133440.0 8940.0 0.23 0.2685 0.9758 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E11 compound treatment 10040.0 -116000.0 -3.6 10680.0 -114000.0 -2.96 -4.6336 -0.9953 627 HSCI1_000051 C=CC(=O)c1ccc2ccccc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E12 compound treatment 19080.0 -107000.0 -3.32 18080.0 -106000.0 -2.76 -4.2996 -0.9959 536 HSCI1_000052 ONC(=O)CCCCCN1C(=O)c2cccc3cccc(C1=O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E13 compound treatment 130920.0 4840.0 0.15 139480.0 15000.0 0.39 0.3812 0.9139 593 HSCI1_000053 Oc1ccc2ccc(=O)oc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E14 compound treatment 11720.0 -114000.0 -3.54 12800.0 -112000.0 -2.9 -4.5578 -0.9951 3055208 HSCI1_000054 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E15 mock treatment 129840.0 3760.0 0.12 131640.0 7140.0 0.19 0.2135 0.9747 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E16 mock treatment 125160.0 -925.0 -0.03 123920.0 -576.0 -0.01 -0.0309 -0.9542 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E17 mock treatment 125640.0 -445.0 -0.01 141400.0 16900.0 0.44 0.3008 0.6846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E18 mock treatment 124680.0 -1400.0 -0.04 129480.0 4980.0 0.13 0.0608 0.4449 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E19 compound treatment 120000.0 -6080.0 -0.19 131360.0 6860.0 0.18 -0.0072 -0.0278 1912 HSCI1_000055 [O-][N+](=O)c1cccc2cn[nH]c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E20 compound treatment 12600.0 -113000.0 -3.52 60160.0 -64300.0 -1.67 -3.6684 -0.9422 3175984 HSCI1_000056 CCCC(=O)OCSC(=S)OC1CC2CC1C3CCCC23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E21 compound treatment 85560.0 -40500.0 -1.26 105480.0 -19000.0 -0.49 -1.2373 -0.9169 596 HSCI1_000057 CN(C)c1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E22 compound treatment 12160.0 -114000.0 -3.53 19320.0 -105000.0 -2.73 -4.4284 -0.992 564 HSCI1_000058 Oc1ccc(/C=C(\C#N)/C(=O)NCCCCc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E23 compound treatment 36560.0 -89500.0 -2.77 44880.0 -79600.0 -2.07 -3.4242 -0.9896 2175 HSCI1_000059 CCCCCCCCN1C(=O)C(=C(C)C1(C)O)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 E24 mock treatment 90440.0 -35600.0 -1.1 108760.0 -15700.0 -0.41 -1.0701 -0.9086 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F01 mock treatment 106280.0 -19800.0 -0.61 166720.0 42200.0 1.1 0.3418 0.2719 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F02 mock treatment 137240.0 11200.0 0.35 140720.0 16200.0 0.42 0.5425 0.9951 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F03 mock treatment 132600.0 6520.0 0.2 138680.0 14200.0 0.37 0.4033 0.9599 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F04 mock treatment 150240.0 24200.0 0.75 168280.0 43800.0 1.14 1.3336 0.9794 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F05 compound treatment 85200.0 -40900.0 -1.27 78560.0 -45900.0 -1.19 -1.7397 -0.9996 2108 HSCI1_000060 COc1cc2C/C(=C\c3cc(C)c(O)c(C)c3)/C(=O)c2c(N)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F06 compound treatment 142720.0 16600.0 0.52 126240.0 1740.0 0.05 0.3965 0.7663 2303 HSCI1_000061 COc1cc2CCN3Cc4c(OC)c(O)ccc4CC3c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F07 compound treatment 70720.0 -55400.0 -1.72 55440.0 -69100.0 -1.79 -2.4818 -0.9997 1967 HSCI1_000062 Brc1cccc(Nc2ncnc3cc4[nH]cnc4cc23)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F08 compound treatment 50000.0 -76100.0 -2.36 86960.0 -37500.0 -0.98 -2.3566 -0.9237 1918768 HSCI1_000063 Clc1ccc(C(=O)n2nnc3ccccc23)c(Cl)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F09 mock treatment 142560.0 16500.0 0.51 125480.0 984.0 0.03 0.379 0.7416 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F10 mock treatment 140880.0 14800.0 0.46 117960.0 -6540.0 -0.17 0.2041 0.4174 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F11 compound treatment 137840.0 11800.0 0.36 137240.0 12700.0 0.33 0.4917 0.9989 583 HSCI1_000064 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCCO)nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F12 compound treatment 125880.0 -205.0 -0.01 104640.0 -19900.0 -0.52 -0.3693 -0.7158 1085933 HSCI1_000065 COC(=O)c1ccccc1NC(=O)c2ccc(F)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F13 compound treatment 60920.0 -65200.0 -2.02 87880.0 -36600.0 -0.95 -2.1005 -0.9411 675 HSCI1_000066 Brc1ccc2NC(=O)/C(=C\c3cc4CCCCc4[nH]3)/c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F14 compound treatment 134080.0 8000.0 0.25 139680.0 15200.0 0.39 0.4541 0.9749 2144 HSCI1_000067 O=C(Nc1ccccc1)C2C(=O)NC(=S)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F15 mock treatment 122240.0 -3840.0 -0.12 125560.0 1060.0 0.03 -0.0647 -0.529 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F16 mock treatment 132080.0 6000.0 0.19 122080.0 -2420.0 -0.06 0.087 0.4435 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F17 mock treatment 137680.0 11600.0 0.36 130040.0 5540.0 0.14 0.3559 0.9195 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F18 mock treatment 127200.0 1120.0 0.03 120640.0 -3860.0 -0.1 -0.0464 -0.438 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F19 compound treatment 10160.0 -116000.0 -3.59 11800.0 -113000.0 -2.93 -4.6104 -0.9949 643 HSCI1_000068 CNc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F20 compound treatment 13880.0 -112000.0 -3.48 27880.0 -96600.0 -2.51 -4.2334 -0.9872 122 HSCI1_000069 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F21 compound treatment 65920.0 -60200.0 -1.86 88520.0 -36000.0 -0.93 -1.9792 -0.949 590 HSCI1_000070 CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F22 compound treatment 131960.0 5880.0 0.18 147080.0 22600.0 0.59 0.5436 0.8849 2060831 HSCI1_000071 O=C1CCCC(=O)C1CC2C(=O)CCCC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F23 compound treatment 105680.0 -20400.0 -0.63 102640.0 -21900.0 -0.57 -0.8486 -0.9986 3176054 HSCI1_000072 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1)\[N+]#[C-])/Sc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 F24 mock treatment 86400.0 -39700.0 -1.23 133520.0 9020.0 0.23 -0.7037 -0.5622 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G01 mock treatment 117520.0 -8560.0 -0.27 158600.0 34100.0 0.89 0.4389 0.4745 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G02 compound treatment 9680.0 -116000.0 -3.61 10400.0 -114000.0 -2.96 -4.6466 -0.9953 305 HSCI1_000073 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G03 mock treatment 137200.0 11100.0 0.34 131920.0 7420.0 0.19 0.3799 0.9625 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G04 mock treatment 133760.0 7680.0 0.24 122120.0 -2380.0 -0.06 0.1245 0.5067 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G05 mock treatment 123160.0 -2920.0 -0.09 127240.0 2740.0 0.07 -0.0137 -0.1186 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G06 mock treatment 122720.0 -3360.0 -0.1 120560.0 -3940.0 -0.1 -0.146 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G07 compound treatment 12880.0 -113000.0 -3.51 8720.0 -116000.0 -3.01 -4.6074 -0.9971 2073 HSCI1_000074 CC(=CCC/C(=C/CC/C(=C/CSc1nc[nH]n1)/C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G08 compound treatment 100280.0 -25800.0 -0.8 103680.0 -20800.0 -0.54 -0.9478 -0.9819 3176055 HSCI1_000075 CCOc1cc(/C=C(/C#N)\C(=O)N)cc(CSc2ccccc2)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G09 compound treatment 123320.0 -2760.0 -0.09 130960.0 6460.0 0.17 0.0582 0.3086 2335 HSCI1_000076 COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G10 compound treatment 11840.0 -114000.0 -3.54 13360.0 -111000.0 -2.89 -4.5449 -0.9949 3055275 HSCI1_000077 CC(C)(C)OC(=O)NC(CC(=O)CCl)C(=O)Cc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G11 compound treatment 10480.0 -116000.0 -3.58 9440.0 -115000.0 -2.99 -4.6467 -0.996 2134 HSCI1_000078 COc1cc(O)c(cc1/C=C/C(=O)c2ccc(O)cc2)C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G12 compound treatment 115560.0 -10500.0 -0.33 109680.0 -14800.0 -0.38 -0.5028 -0.9966 3055277 HSCI1_000079 COc1cc(cc(CN(C)CCc2ccc(cc2)[N+](=O)[O-])c1O)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G13 compound treatment 121800.0 -4280.0 -0.13 115960.0 -8540.0 -0.22 -0.2507 -0.9699 1002387 HSCI1_000080 Oc1ccc(C=C(C#N)C#N)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G14 compound treatment 121960.0 -4120.0 -0.13 133480.0 8980.0 0.23 0.0747 0.2806 3176058 HSCI1_000081 C[C@@H]1[C@@H](O)[C@@]2(O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@]13O)C2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G15 compound treatment 135320.0 9240.0 0.29 117840.0 -6660.0 -0.17 0.08 0.2394 672 HSCI1_000082 Oc1ccc(CC(C#N)C#N)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G16 compound treatment 55560.0 -70500.0 -2.19 61040.0 -63500.0 -1.65 -2.711 -0.9904 3176059 HSCI1_000083 OCc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G17 mock treatment 120800.0 -5280.0 -0.16 124360.0 -136.0 0.0 -0.1183 -0.7222 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G18 mock treatment 121840.0 -4240.0 -0.13 112640.0 -11900.0 -0.31 -0.3108 -0.928 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G19 mock treatment 130640.0 4560.0 0.14 129160.0 4660.0 0.12 0.1855 0.9971 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G20 mock treatment 114400.0 -11700.0 -0.36 117000.0 -7500.0 -0.19 -0.3937 -0.9577 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G21 compound treatment 139040.0 13000.0 0.4 128680.0 4180.0 0.11 0.3607 0.8674 3415700 HSCI1_000084 CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G22 compound treatment 8960.0 -117000.0 -3.63 9600.0 -115000.0 -2.99 -4.6771 -0.9953 3176060 HSCI1_000085 CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]4CCCC[C@@H]4N)nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G23 compound treatment 83640.0 -42400.0 -1.32 87160.0 -37300.0 -0.97 -1.6159 -0.9888 3055326 HSCI1_000086 Cc1ccc(cc1)c2cn3c4CCCCc4sc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 G24 mock treatment 103480.0 -22600.0 -0.7 123080.0 -1420.0 -0.04 -0.5213 -0.7432 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H01 mock treatment 122480.0 -3600.0 -0.11 147160.0 22700.0 0.59 0.3374 0.5629 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H02 compound treatment 133240.0 7160.0 0.22 138960.0 14500.0 0.38 0.4225 0.9683 1886 HSCI1_000087 NCCOB(c1ccccc1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H03 mock treatment 135920.0 9840.0 0.3 134200.0 9700.0 0.25 0.3938 0.9956 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H04 mock treatment 134120.0 8040.0 0.25 148640.0 24100.0 0.63 0.6196 0.9181 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H05 mock treatment 144280.0 18200.0 0.56 138600.0 14100.0 0.37 0.6578 0.9782 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H06 mock treatment 122040.0 -4040.0 -0.13 141000.0 16500.0 0.43 0.2146 0.4803 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H07 compound treatment 33040.0 -93000.0 -2.88 22280.0 -102000.0 -2.66 -3.9165 -0.9992 2278 HSCI1_000088 Oc1cc(ccc1NC(=O)Nc2ccccc2Br)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H08 compound treatment 9520.0 -117000.0 -3.61 9000.0 -115000.0 -3.0 -4.6758 -0.9958 1891 HSCI1_000089 Clc1oc(=O)c2ccccc2c1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H09 compound treatment 46480.0 -79600.0 -2.47 34640.0 -89900.0 -2.33 -3.395 -0.9996 1966 HSCI1_000090 Cn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H10 compound treatment 137720.0 11600.0 0.36 136240.0 11700.0 0.31 0.4707 0.9966 3176061 HSCI1_000091 CC1(CCC2(C)O1)C(C2C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H11 compound treatment 119720.0 -6360.0 -0.2 95000.0 -29500.0 -0.77 -0.6814 -0.861 291 HSCI1_000092 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H12 compound treatment 125880.0 -205.0 -0.01 115600.0 -8900.0 -0.23 -0.1679 -0.7262 3055333 HSCI1_000093 O=C/1Nc2ccccc2\C1=C/c3c[nH]cn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H13 compound treatment 115880.0 -10200.0 -0.32 95280.0 -29200.0 -0.76 -0.7604 -0.9246 3176062 HSCI1_000094 CC[C@@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H14 compound treatment 135000.0 8920.0 0.28 134240.0 9740.0 0.25 0.3743 0.9991 1040138 HSCI1_000095 COc1cc(C=O)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H15 compound treatment 161160.0 35100.0 1.09 167120.0 42600.0 1.11 1.5516 1.0 3176063 HSCI1_000096 CC(C)n1cnc2c(NCc3ccccc3O)nc(NCCCO)nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H16 compound treatment 133160.0 7080.0 0.22 120240.0 -4260.0 -0.11 0.0768 0.3128 2109 HSCI1_000097 OCc1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H17 mock treatment 126600.0 515.0 0.02 123600.0 -896.0 -0.02 -0.0052 -0.1836 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H18 mock treatment 120600.0 -5480.0 -0.17 124680.0 184.0 0.0 -0.1168 -0.687 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H19 mock treatment 131240.0 5160.0 0.16 142320.0 17800.0 0.46 0.4404 0.899 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H20 mock treatment 133080.0 7000.0 0.22 120800.0 -3700.0 -0.1 0.0853 0.36 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H21 compound treatment 113160.0 -12900.0 -0.4 113440.0 -11100.0 -0.29 -0.4863 -0.9867 3176064 HSCI1_000098 O/N=C\1/C(=C\2/C(=O)Nc3ccc(cc23)S(=O)(=O)O)/Nc4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H22 compound treatment 135560.0 9480.0 0.29 123920.0 -576.0 -0.01 0.197 0.6702 2069332 HSCI1_000099 CC(=O)/C(=N/O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H23 compound treatment 69480.0 -56600.0 -1.75 81160.0 -43300.0 -1.13 -2.0364 -0.977 642 HSCI1_000100 COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 H24 mock treatment 101800.0 -24300.0 -0.75 110840.0 -13700.0 -0.35 -0.783 -0.9412 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I01 mock treatment 123360.0 -2720.0 -0.08 147160.0 22700.0 0.59 0.3567 0.5996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I02 compound treatment 55160.0 -70900.0 -2.2 37040.0 -87500.0 -2.27 -3.1607 -0.9999 666 HSCI1_000101 CC(C)c1cc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc(C(C)C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I03 compound treatment 105720.0 -20400.0 -0.63 7680.0 -117000.0 -3.04 -2.5924 -0.8362 3176066 HSCI1_000102 CCCCC/C=C/C/C=C/C\C=C\C\C=C\CCCC(=O)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I04 compound treatment 11400.0 -115000.0 -3.55 9400.0 -115000.0 -2.99 -4.6273 -0.9963 2104844 HSCI1_000103 Oc1ccc(O)c(CNc2ccc(cc2)C(=O)OC3(CC4CC5CC(C4)C3)C5)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I05 mock treatment 122720.0 -3360.0 -0.1 127440.0 2940.0 0.08 -0.0196 -0.1519 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I06 mock treatment 131720.0 5640.0 0.17 124200.0 -296.0 -0.01 0.118 0.6753 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I07 mock treatment 129960.0 3880.0 0.12 123320.0 -1180.0 -0.03 0.0633 0.5108 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I08 mock treatment 122040.0 -4040.0 -0.13 116440.0 -8060.0 -0.21 -0.2366 -0.9699 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I09 compound treatment 10560.0 -116000.0 -3.58 9840.0 -115000.0 -2.98 -4.6376 -0.9958 626 HSCI1_000104 CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I10 compound treatment 124280.0 -1800.0 -0.06 120280.0 -4220.0 -0.11 -0.117 -0.9513 3055340 HSCI1_000105 Cc1ccc(N/N=C/2\C(=O)Nc3ccc(Br)cc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I11 compound treatment 120240.0 -5840.0 -0.18 132120.0 7620.0 0.2 0.012 0.0447 568 HSCI1_000106 COc1ccc(C=C(C#N)C#N)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I12 compound treatment 74360.0 -51700.0 -1.6 72240.0 -52300.0 -1.36 -2.0933 -0.9966 3176067 HSCI1_000107 Ic1cccc(CSc2nnc(o2)c3ccncc3)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I13 compound treatment 123360.0 -2720.0 -0.08 97960.0 -26500.0 -0.69 -0.5472 -0.7878 558 HSCI1_000108 Oc1ccc(C=C(C#N)C#N)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I14 compound treatment 31800.0 -94300.0 -2.92 31160.0 -93300.0 -2.43 -3.7806 -0.9957 3176068 HSCI1_000109 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I15 compound treatment 35120.0 -91000.0 -2.82 37160.0 -87300.0 -2.27 -3.5976 -0.9942 1975 HSCI1_000110 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1c5ccc(=O)oc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I16 compound treatment 133200.0 7120.0 0.22 115320.0 -9180.0 -0.24 -0.0127 -0.0391 1001980 HSCI1_000111 CCCCCCCC/C=C/CCCCCCCC(=O)OCC(CO)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I17 compound treatment 10240.0 -116000.0 -3.59 9280.0 -115000.0 -2.99 -4.6549 -0.9959 130 HSCI1_000112 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I18 compound treatment 15200.0 -111000.0 -3.44 15880.0 -109000.0 -2.82 -4.425 -0.9952 1922639 HSCI1_000113 CC(C)C(N1C(=O)/C(=C/c2ccc(Br)cc2)/SC1=S)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I19 mock treatment 157960.0 31900.0 0.99 131000.0 6500.0 0.17 0.8179 0.8162 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I20 mock treatment 122920.0 -3160.0 -0.1 131920.0 7420.0 0.19 0.0671 0.3099 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I21 mock treatment 143760.0 17700.0 0.55 137560.0 13100.0 0.34 0.6273 0.9735 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I22 mock treatment 139600.0 13500.0 0.42 148200.0 23700.0 0.62 0.7316 0.9823 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I23 compound treatment 93600.0 -32500.0 -1.01 86640.0 -37900.0 -0.98 -1.4072 -0.9999 565 HSCI1_000114 Oc1cc(C=C(C#N)C#N)cc(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 I24 mock treatment 106640.0 -19400.0 -0.6 109960.0 -14500.0 -0.38 -0.6931 -0.9747 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J01 mock treatment 126760.0 675.0 0.02 142720.0 18200.0 0.47 0.3496 0.7376 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J02 compound treatment 69720.0 -56400.0 -1.75 37440.0 -87100.0 -2.26 -2.8344 -0.9918 3176070 HSCI1_000115 OC(=O)c1c(Br)c(Br)c(Br)c(Br)c1c2c3ccc(O)cc3oc4cc(=O)ccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J03 compound treatment 127040.0 955.0 0.03 95200.0 -29300.0 -0.76 -0.5173 -0.6791 294 HSCI1_000116 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J04 compound treatment 146160.0 20100.0 0.62 153640.0 29100.0 0.76 0.9753 0.9952 3055387 HSCI1_000117 C[C@@]12CCC3C(CCC4=C[C@H](O)CCC34)C2CC[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J05 mock treatment 138880.0 12800.0 0.4 127920.0 3420.0 0.09 0.3432 0.8448 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J06 mock treatment 121920.0 -4160.0 -0.13 140600.0 16100.0 0.42 0.2046 0.4673 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J07 mock treatment 144960.0 18900.0 0.58 118840.0 -5660.0 -0.15 0.3096 0.5134 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J08 mock treatment 112960.0 -13100.0 -0.41 130840.0 6340.0 0.16 -0.171 -0.3897 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J09 compound treatment 133800.0 7720.0 0.24 105240.0 -19300.0 -0.5 -0.1848 -0.3332 633 HSCI1_000118 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J10 compound treatment 10160.0 -116000.0 -3.59 8840.0 -116000.0 -3.01 -4.6647 -0.9961 2251 HSCI1_000119 O=C(NC1=CC(=O)c2ccccc2C1=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J11 compound treatment 10400.0 -116000.0 -3.58 9800.0 -115000.0 -2.98 -4.6419 -0.9958 645 HSCI1_000120 Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J12 compound treatment 73560.0 -52500.0 -1.63 71040.0 -53500.0 -1.39 -2.1329 -0.9969 3176071 HSCI1_000121 Nc1nc(Cl)nc2n(cnc12)C3C[C@@H](O)C(CO)O3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J13 compound treatment 87240.0 -38800.0 -1.2 84600.0 -39900.0 -1.04 -1.5841 -0.9972 646 HSCI1_000122 CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J14 compound treatment 40440.0 -85600.0 -2.65 40000.0 -84500.0 -2.2 -3.4288 -0.9956 854065 HSCI1_000123 CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J15 compound treatment 70160.0 -55900.0 -1.73 53600.0 -70900.0 -1.84 -2.5278 -0.9995 670 HSCI1_000124 CN(C)S(=O)(=O)c1ccc2NC(=O)/C(=C\c3cc4CCCCc4[nH]3)/c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J16 compound treatment 40720.0 -85400.0 -2.64 23880.0 -101000.0 -2.61 -3.7189 -1.0 3176072 HSCI1_000125 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)c4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J17 compound treatment 43320.0 -82800.0 -2.56 49960.0 -74500.0 -1.94 -3.1828 -0.9904 1996 HSCI1_000126 CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J18 compound treatment 142240.0 16200.0 0.5 135920.0 11400.0 0.3 0.5638 0.9689 2268 HSCI1_000127 CC(=CC1C(C(=O)OCc2coc(Cc3ccccc3)c2)C1(C)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J19 mock treatment 136960.0 10900.0 0.34 130320.0 5820.0 0.15 0.3453 0.9347 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J20 mock treatment 129120.0 3040.0 0.09 125800.0 1300.0 0.03 0.0904 0.9049 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J21 mock treatment 144880.0 18800.0 0.58 141160.0 16700.0 0.43 0.7179 0.9893 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J22 mock treatment 126800.0 715.0 0.02 122000.0 -2500.0 -0.06 -0.0302 -0.4405 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J23 compound treatment 25880.0 -100000.0 -3.1 35040.0 -89500.0 -2.32 -3.839 -0.9898 654 HSCI1_000128 CC(C)C(CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 J24 mock treatment 96920.0 -29200.0 -0.9 129920.0 5420.0 0.14 -0.5393 -0.5897 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K01 mock treatment 135120.0 9040.0 0.28 100640.0 -23900.0 -0.62 -0.2404 -0.3534 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K02 compound treatment 120360.0 -5720.0 -0.18 64160.0 -60300.0 -1.57 -1.234 -0.7821 3055432 HSCI1_000129 CCOC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cc(OC)c(OC)c(OC)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K03 compound treatment 130320.0 4240.0 0.13 106840.0 -17700.0 -0.46 -0.2316 -0.4854 570 HSCI1_000130 NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K04 compound treatment 135040.0 8960.0 0.28 121520.0 -2980.0 -0.08 0.1415 0.4913 1005921 HSCI1_000131 OCC1OC(Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K05 compound treatment 131520.0 5440.0 0.17 113040.0 -11500.0 -0.3 -0.0914 -0.2673 559 HSCI1_000132 OC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K06 compound treatment 112440.0 -13600.0 -0.42 81680.0 -42800.0 -1.11 -1.0856 -0.9122 620 HSCI1_000133 COc1cc(/C=C(\C#N)/C(=O)c2ccc(O)c(O)c2)cc(I)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K07 mock treatment 115080.0 -11000.0 -0.34 118880.0 -5620.0 -0.15 -0.3443 -0.9283 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K08 mock treatment 120000.0 -6080.0 -0.19 124600.0 104.0 0.0 -0.1314 -0.6969 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K09 mock treatment 126360.0 275.0 0.01 134760.0 10300.0 0.27 0.1946 0.7293 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K10 mock treatment 133680.0 7600.0 0.24 124360.0 -136.0 0.0 0.1639 0.6964 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K11 compound treatment 126600.0 515.0 0.02 111160.0 -13300.0 -0.35 -0.2337 -0.6738 553 HSCI1_000134 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K12 compound treatment 15120.0 -111000.0 -3.44 11280.0 -113000.0 -2.94 -4.5112 -0.997 3176129 HSCI1_000135 Oc1cc(/C=C(\C#N)/C(=O)NCCCc2ccccc2)cc(I)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K13 compound treatment 111680.0 -14400.0 -0.45 93240.0 -31300.0 -0.81 -0.8899 -0.9603 1000035 HSCI1_000136 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K14 compound treatment 118240.0 -7840.0 -0.24 85480.0 -39000.0 -1.01 -0.8887 -0.8525 1 HSCI1_000137 Oc1ccc(/C=C(\C#N)/C(=O)NCCCNC(=O)\C(=C\c2ccc(O)c(O)c2)\C#N)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K15 mock treatment 119720.0 -6360.0 -0.2 132920.0 8420.0 0.22 0.0153 0.052 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K16 mock treatment 138560.0 12500.0 0.39 114960.0 -9540.0 -0.25 0.0981 0.2137 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K17 compound treatment 136320.0 10200.0 0.32 112640.0 -11900.0 -0.31 0.0064 0.0145 554 HSCI1_000138 Oc1cc(C=C(C#N)C#N)cc([N+](=O)[O-])c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K18 compound treatment 98720.0 -27400.0 -0.85 80560.0 -43900.0 -1.14 -1.4068 -0.9893 3176130 HSCI1_000139 CN(C)c1ccc2c(c3ccccc3C(=O)O)c4ccc(=[N+](C)C)cc4oc2c1.CC(=O)NCCSS(=O)(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K19 compound treatment 140720.0 14600.0 0.45 127720.0 3220.0 0.08 0.3799 0.8238 555 HSCI1_000140 Cc1cc2ncc(nc2cc1C)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K20 compound treatment 125800.0 -285.0 -0.01 126640.0 2140.0 0.06 0.0331 0.5877 2311 HSCI1_000141 COC(=O)c1c(c2cc(OC)c(OC)c(OC)c2)c3ccnc(OCc4ncccn4)c3c(=O)n1Cc5ccnc(C)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K21 mock treatment 112760.0 -13300.0 -0.41 127440.0 2940.0 0.08 -0.2379 -0.5665 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K22 mock treatment 128200.0 2120.0 0.07 113320.0 -11200.0 -0.29 -0.159 -0.5341 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K23 mock treatment 132000.0 5920.0 0.18 128880.0 4380.0 0.11 0.2101 0.9738 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 K24 mock treatment 125360.0 -725.0 -0.02 104880.0 -19600.0 -0.51 -0.3763 -0.7375 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L01 mock treatment 127160.0 1080.0 0.03 112960.0 -11500.0 -0.3 -0.1884 -0.6247 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L02 compound treatment 129080.0 3000.0 0.09 114520.0 -9980.0 -0.26 -0.1177 -0.4274 1995 HSCI1_000142 CN(C1CCCCC1)C(=O)CCCOc2ccc3[nH]c(=O)ccc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L03 compound treatment 25040.0 -101000.0 -3.13 21840.0 -103000.0 -2.67 -4.0999 -0.9968 3176131 HSCI1_000143 Nc1ncnc2n(cc(I)c12)C3OC(CO)[C@H](O)[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L04 compound treatment 130200.0 4120.0 0.13 111280.0 -13200.0 -0.34 -0.1527 -0.4168 3055484 HSCI1_000144 COc1cc(SC)ccc1c2nc3ccncc3[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L05 compound treatment 113680.0 -12400.0 -0.38 93240.0 -31300.0 -0.81 -0.846 -0.9416 1907775 HSCI1_000145 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L06 compound treatment 72600.0 -53500.0 -1.66 22680.0 -102000.0 -2.65 -3.0425 -0.9746 3176132 HSCI1_000146 COc1ccc(cc1)C(=C2C(=O)Nc3ccccc23)c4ccc(OC)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L07 mock treatment 124960.0 -1120.0 -0.03 123760.0 -736.0 -0.02 -0.0382 -0.9601 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L08 mock treatment 122600.0 -3480.0 -0.11 120120.0 -4380.0 -0.11 -0.1568 -0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L09 mock treatment 132920.0 6840.0 0.21 121120.0 -3380.0 -0.09 0.0877 0.3827 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L10 mock treatment 125360.0 -725.0 -0.02 126640.0 2140.0 0.06 0.0235 0.3914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L11 compound treatment 108440.0 -17600.0 -0.55 96080.0 -28400.0 -0.74 -0.9087 -0.9891 3055486 HSCI1_000147 O=C1NC(=O)c2c1c3c4ccccc4n5C6CCC(O6)n7c8ccccc8c2c7c53 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L12 compound treatment 139400.0 13300.0 0.41 105200.0 -19300.0 -0.5 -0.0628 -0.0967 3176133 HSCI1_000148 OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L13 compound treatment 18320.0 -108000.0 -3.34 17960.0 -107000.0 -2.77 -4.3184 -0.9957 3176134 HSCI1_000149 O/N=C\1/C(=C\2/C(=O)Nc3ccc(I)cc23)/Nc4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L14 compound treatment 118000.0 -8080.0 -0.25 122600.0 -1900.0 -0.05 -0.212 -0.8303 3055490 HSCI1_000150 COc1cc(ccc1c2nc3ccncc3[nH]2)S(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L15 mock treatment 109200.0 -16900.0 -0.52 115360.0 -9140.0 -0.24 -0.5378 -0.9361 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L16 mock treatment 113040.0 -13000.0 -0.4 113600.0 -10900.0 -0.28 -0.486 -0.9848 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L17 compound treatment 113000.0 -13100.0 -0.41 104600.0 -19900.0 -0.52 -0.6522 -0.9928 3176135 HSCI1_000151 C[S+](O)c1ccc(CSc2nc(c([nH]2)c3ccc(F)cc3)c4ccncc4)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L18 compound treatment 120680.0 -5400.0 -0.17 120280.0 -4220.0 -0.11 -0.1959 -0.9788 2109556 HSCI1_000152 Nc1n[nH]c2nc3ccccc3nc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L19 compound treatment 68680.0 -57400.0 -1.78 50600.0 -73900.0 -1.92 -2.6154 -0.9993 3176136 HSCI1_000153 C[C@@H]1C2NCC(C)C[C@H]2O[C@@]31CCC4C5CC=C6CC(O)CCC6(C)C5C(=O)C4=C3C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L20 compound treatment 15880.0 -110000.0 -3.41 18320.0 -106000.0 -2.76 -4.3653 -0.9944 3055494 HSCI1_000154 OB(O)c1ccc(cc1)C(=O)/C=C/c2ccc(I)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L21 mock treatment 117960.0 -8120.0 -0.25 123840.0 -656.0 -0.02 -0.1901 -0.7533 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L22 mock treatment 126160.0 75.2 0.0 127280.0 2780.0 0.07 0.0528 0.7295 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L23 mock treatment 119320.0 -6760.0 -0.21 121720.0 -2780.0 -0.07 -0.1992 -0.8987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 L24 mock treatment 112600.0 -13500.0 -0.42 120000.0 -4500.0 -0.12 -0.3781 -0.8714 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M01 mock treatment 123840.0 -2240.0 -0.07 111600.0 -12900.0 -0.34 -0.2861 -0.8361 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M02 compound treatment 82440.0 -43600.0 -1.35 18360.0 -106000.0 -2.76 -2.9062 -0.9462 2095175 HSCI1_000155 Oc1ccc(/C=C(\C#N)/C(=O)NC2CCC(CC3CCC(CC3)NC(=O)\C(=C\c4ccc(O)c(O)c4)\C#N)CC2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M03 compound treatment 138400.0 12300.0 0.38 94080.0 -30400.0 -0.79 -0.289 -0.3293 552 HSCI1_000156 NC(=C(C#N)C#N)/C(=C/c1ccc(O)cc1)/C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M04 compound treatment 141440.0 15400.0 0.48 102840.0 -21700.0 -0.56 -0.0615 -0.0834 613 HSCI1_000157 Oc1cc(/C=C/c2ccc(O)c(O)c2)oc(=O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M05 compound treatment 143400.0 17300.0 0.54 120920.0 -3580.0 -0.09 0.3137 0.5761 657 HSCI1_000158 COc1ccc(/C=C(\C#N)/c2cccnc2)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M06 compound treatment 78960.0 -47100.0 -1.46 42320.0 -82200.0 -2.14 -2.5423 -0.9828 3176139 HSCI1_000159 CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCCCCCCCC)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M07 compound treatment 135840.0 9760.0 0.3 111640.0 -12900.0 -0.33 -0.0225 -0.0499 671 HSCI1_000160 NC(=C(C#N)C#N)/C(=C/c1cc(O)c(O)c(O)c1)/C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M08 compound treatment 132640.0 6560.0 0.2 123040.0 -1460.0 -0.04 0.1169 0.5656 3176140 HSCI1_000161 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)[C@@H]3S 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M09 mock treatment 114960.0 -11100.0 -0.34 121440.0 -3060.0 -0.08 -0.2999 -0.8478 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M10 mock treatment 119720.0 -6360.0 -0.2 113840.0 -10700.0 -0.28 -0.3352 -0.9862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M11 mock treatment 122640.0 -3440.0 -0.11 127960.0 3460.0 0.09 -0.0118 -0.0848 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M12 mock treatment 119880.0 -6200.0 -0.19 121040.0 -3460.0 -0.09 -0.1994 -0.9399 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M13 mock treatment 135320.0 9240.0 0.29 125440.0 944.0 0.02 0.2197 0.7649 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M14 mock treatment 122800.0 -3280.0 -0.1 122800.0 -1700.0 -0.04 -0.1031 -0.9299 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M15 compound treatment 73480.0 -52600.0 -1.63 44320.0 -80200.0 -2.08 -2.6256 -0.9926 585 HSCI1_000162 Oc1ccc(C(=O)/C=C/c2ccc(O)c(O)c2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M16 compound treatment 119520.0 -6560.0 -0.2 61520.0 -63000.0 -1.64 -1.3009 -0.7889 2024 HSCI1_000163 CN(N=O)c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M17 compound treatment 12800.0 -113000.0 -3.51 13600.0 -111000.0 -2.88 -4.5195 -0.9952 569 HSCI1_000164 COC(=O)c1ccc(NCc2cc(O)ccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M18 compound treatment 143760.0 17700.0 0.55 102440.0 -22100.0 -0.57 -0.018 -0.0227 1890 HSCI1_000165 CN(N=O)c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M19 compound treatment 141720.0 15600.0 0.48 108720.0 -15800.0 -0.41 0.0527 0.083 1008455 HSCI1_000166 BrCC(=O)c1ccc(Br)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M20 compound treatment 123800.0 -2280.0 -0.07 88080.0 -36400.0 -0.95 -0.7191 -0.7579 3176141 HSCI1_000167 CCN(N=O)c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M21 compound treatment 97920.0 -28200.0 -0.87 87280.0 -37200.0 -0.97 -1.3008 -0.9987 560 HSCI1_000168 Oc1ccc(/C=C(\C#N)/C(=O)Nc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M22 compound treatment 29720.0 -96400.0 -2.99 52480.0 -72000.0 -1.87 -3.4344 -0.9747 566 HSCI1_000169 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M23 mock treatment 134280.0 8200.0 0.25 130920.0 6420.0 0.17 0.2976 0.9793 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 M24 mock treatment 125440.0 -645.0 -0.02 124200.0 -296.0 -0.01 -0.0196 -0.9141 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N01 mock treatment 136000.0 9920.0 0.31 115120.0 -9380.0 -0.24 0.045 0.1147 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N02 compound treatment 148120.0 22000.0 0.68 122320.0 -2180.0 -0.06 0.4428 0.6463 837968 HSCI1_000170 Nc1ncnc2n(cnc12)C3CCCO3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N03 compound treatment 137680.0 11600.0 0.36 112320.0 -12200.0 -0.32 0.0303 0.0634 3176143 HSCI1_000171 CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)CCC(=O)O)[C@@]3(C)O[C@](C)(CC(=O)[C@@]32O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N04 compound treatment 95720.0 -30400.0 -0.94 50280.0 -74200.0 -1.93 -2.0288 -0.9456 831810 HSCI1_000172 Brc1c(Br)c(Br)c2[nH]nnc2c1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N05 compound treatment 15800.0 -110000.0 -3.42 9600.0 -115000.0 -2.99 -4.5272 -0.9977 3054768 HSCI1_000173 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C\[C@H](O)CCC[C@@H](C)C/C=C\[C@H]4C(=O)C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N06 compound treatment 11120.0 -115000.0 -3.56 5720.0 -119000.0 -3.09 -4.701 -0.9974 3054769 HSCI1_000174 Cn1sc(=O)n(Cc2ccccc2)c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N07 compound treatment 49080.0 -77000.0 -2.39 19040.0 -105000.0 -2.74 -3.6246 -0.9976 621 HSCI1_000175 CS(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4cccc(I)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N08 compound treatment 72480.0 -53600.0 -1.66 42120.0 -82400.0 -2.14 -2.6879 -0.9921 3054770 HSCI1_000176 c1ccc(cc1)c2n[nH]c3c2oc4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N09 mock treatment 134360.0 8280.0 0.26 113240.0 -11300.0 -0.29 -0.0255 -0.0656 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N10 mock treatment 123000.0 -3080.0 -0.1 124960.0 464.0 0.01 -0.0591 -0.6132 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N11 mock treatment 121880.0 -4200.0 -0.13 120040.0 -4460.0 -0.12 -0.174 -0.9983 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N12 mock treatment 124120.0 -1960.0 -0.06 125640.0 1140.0 0.03 -0.022 -0.3253 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N13 mock treatment 125960.0 -125.0 0.0 124520.0 23.6 0.0 -0.0023 -0.5879 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N14 mock treatment 123760.0 -2320.0 -0.07 135000.0 10500.0 0.27 0.142 0.5032 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N15 compound treatment 63560.0 -62500.0 -1.94 31240.0 -93300.0 -2.42 -3.0832 -0.9939 3176144 HSCI1_000177 CC1C2C(Cc3ccccc3)NC(=O)C42OC(=O)O/C=C\C(C)(O)C(=O)C(C)C/C=C\C4C5OC51C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N16 compound treatment 135480.0 9400.0 0.29 133000.0 8500.0 0.22 0.3621 0.9907 1056418 HSCI1_000178 Nc1ncnc2n(cnc12)C3CCC(CO)O3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N17 compound treatment 119960.0 -6120.0 -0.19 111000.0 -13500.0 -0.35 -0.3822 -0.9584 2177 HSCI1_000179 CC(C)CC[C@@H](O)[C@](C)(O)C1CC[C@@]2(O)C3=CC(=O)[C@]4(O)C[C@@H](O)[C@@H](O)C[C@]4(C)C3[C@H](O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N18 compound treatment 55480.0 -70600.0 -2.19 34440.0 -90100.0 -2.34 -3.2015 -0.9994 3054771 HSCI1_000180 COc1ccc2NC(=O)/C(=C\c3c[nH]cn3)/c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N19 compound treatment 107440.0 -18600.0 -0.58 82160.0 -42300.0 -1.1 -1.1863 -0.9548 3176146 HSCI1_000181 CCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)CCC)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N20 compound treatment 7800.0 -118000.0 -3.66 5080.0 -119000.0 -3.1 -4.7855 -0.9966 2127 HSCI1_000182 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N21 compound treatment 7200.0 -119000.0 -3.68 5160.0 -119000.0 -3.1 -4.7972 -0.9963 3054772 HSCI1_000183 CC(C)(O)/C=C/C(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4C(C=C(O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N22 compound treatment 22840.0 -103000.0 -3.2 16320.0 -108000.0 -2.81 -4.2495 -0.9979 1937872 HSCI1_000184 [O-][N+](=O)c1ccccc1c2ccc(C=C3C(=O)N(C(=S)N(C3=O)c4ccccc4)c5ccccc5)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N23 mock treatment 122840.0 -3240.0 -0.1 131840.0 7340.0 0.19 0.0638 0.2959 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 N24 mock treatment 108280.0 -17800.0 -0.55 128520.0 4020.0 0.1 -0.3162 -0.5631 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O01 mock treatment 104120.0 -22000.0 -0.68 107480.0 -17000.0 -0.44 -0.7939 -0.9782 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O02 mock treatment 131160.0 5080.0 0.16 102680.0 -21800.0 -0.57 -0.2896 -0.4924 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O03 compound treatment 31400.0 -94700.0 -2.93 8920.0 -116000.0 -3.0 -4.1979 -0.9999 5 HSCI1_000185 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O04 compound treatment 53680.0 -72400.0 -2.24 6600.0 -118000.0 -3.06 -3.7524 -0.9883 2090 HSCI1_000186 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O05 compound treatment 15720.0 -110000.0 -3.42 5480.0 -119000.0 -3.09 -4.6047 -0.9987 2107241 HSCI1_000187 ClC1=C(N2C(=O)CCC2=O)C(=O)c3ccccc3C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O06 compound treatment 123200.0 -2880.0 -0.09 111600.0 -12900.0 -0.34 -0.3001 -0.8655 651 HSCI1_000188 Nc1ncnc2n(ncc12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O07 compound treatment 104920.0 -21200.0 -0.66 66960.0 -57500.0 -1.49 -1.5208 -0.9316 562 HSCI1_000189 Oc1ccc(/C=C(\C#N)/C(=O)c2ccc(O)c(O)c2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O08 compound treatment 122320.0 -3760.0 -0.12 110520.0 -14000.0 -0.36 -0.3393 -0.8895 3176147 HSCI1_000190 CS/C(=C(\C#N)/C(=C(\N)/SC)/[N+]#[C-])/N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O09 compound treatment 118520.0 -7560.0 -0.23 75280.0 -49200.0 -1.28 -1.07 -0.823 3176148 HSCI1_000191 OCc1cc2ncnc(Nc3ccc(O)cc3)c2cc1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O10 compound treatment 80920.0 -45200.0 -1.4 33360.0 -91100.0 -2.37 -2.6639 -0.9685 3054774 HSCI1_000192 Nc1ccc(cc1)c2cc(=O)c3cc(O)ccc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O11 mock treatment 126000.0 -84.8 0.0 110840.0 -13700.0 -0.35 -0.2528 -0.7123 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O12 mock treatment 109280.0 -16800.0 -0.52 118080.0 -6420.0 -0.17 -0.4861 -0.8891 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O13 mock treatment 74720.0 -51400.0 -1.59 51000.0 -73500.0 -1.91 -2.4757 -0.9959 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O14 mock treatment 130200.0 4120.0 0.13 103200.0 -21300.0 -0.55 -0.3011 -0.5303 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O15 compound treatment 19440.0 -107000.0 -3.3 8840.0 -116000.0 -3.01 -4.4614 -0.9989 3176208 HSCI1_000193 COc1ccc(N=O)c(CCc2cc(OC)ccc2N=O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O16 compound treatment 135080.0 9000.0 0.28 109280.0 -15200.0 -0.4 -0.0825 -0.1705 3054775 HSCI1_000194 CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)OCCF 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O17 compound treatment 85480.0 -40600.0 -1.26 50520.0 -74000.0 -1.92 -2.2488 -0.9789 1860 HSCI1_000195 CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O18 compound treatment 136040.0 9960.0 0.31 74120.0 -50400.0 -1.31 -0.7074 -0.5261 634 HSCI1_000196 OC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O19 compound treatment 143200.0 17100.0 0.53 117720.0 -6780.0 -0.18 0.2505 0.4483 589 HSCI1_000197 Nc1cc(Nc2ccc(cc2)S(=O)(=O)N)ncn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O20 compound treatment 12200.0 -114000.0 -3.53 8400.0 -116000.0 -3.02 -4.6281 -0.997 3054776 HSCI1_000198 Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O21 compound treatment 85280.0 -40800.0 -1.26 60040.0 -64500.0 -1.67 -2.0782 -0.9904 557 HSCI1_000199 Cc1cc2ncc(nc2cc1C)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O22 compound treatment 11080.0 -115000.0 -3.56 9000.0 -115000.0 -3.0 -4.6417 -0.9963 1000586 HSCI1_000200 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O23 mock treatment 121400.0 -4680.0 -0.15 131920.0 7420.0 0.19 0.0337 0.1398 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 O24 mock treatment 108640.0 -17400.0 -0.54 106240.0 -18300.0 -0.47 -0.7176 -0.9979 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P01 mock treatment 73080.0 -53000.0 -1.64 91000.0 -33500.0 -0.87 -1.7767 -0.9559 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P02 mock treatment 110240.0 -15800.0 -0.49 94560.0 -29900.0 -0.78 -0.8972 -0.9754 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P03 mock treatment 124040.0 -2040.0 -0.06 90520.0 -34000.0 -0.88 -0.669 -0.7559 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P04 mock treatment 125680.0 -405.0 -0.01 93440.0 -31100.0 -0.81 -0.5795 -0.718 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P05 mock treatment 130960.0 4880.0 0.15 95360.0 -29100.0 -0.76 -0.4285 -0.5551 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P06 mock treatment 115200.0 -10900.0 -0.34 102280.0 -22200.0 -0.58 -0.6467 -0.9672 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P07 mock treatment 112680.0 -13400.0 -0.42 85560.0 -38900.0 -1.01 -1.0091 -0.9227 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P08 mock treatment 139320.0 13200.0 0.41 91240.0 -33300.0 -0.86 -0.321 -0.3356 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P09 mock treatment 114560.0 -11500.0 -0.36 90520.0 -34000.0 -0.88 -0.8767 -0.9207 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P10 mock treatment 116000.0 -10100.0 -0.31 87880.0 -36600.0 -0.95 -0.8937 -0.8924 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P11 mock treatment 132720.0 6640.0 0.21 88280.0 -36200.0 -0.94 -0.52 -0.5399 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P12 mock treatment 110520.0 -15600.0 -0.48 111280.0 -13200.0 -0.34 -0.5838 -0.9861 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P13 mock treatment 162120.0 36000.0 1.12 87080.0 -37400.0 -0.97 0.1021 0.0689 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P14 mock treatment 135720.0 9640.0 0.3 97640.0 -26900.0 -0.7 -0.2823 -0.372 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P15 mock treatment 130640.0 4560.0 0.14 93360.0 -31100.0 -0.81 -0.4723 -0.5751 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P16 mock treatment 120120.0 -5960.0 -0.18 89120.0 -35400.0 -0.92 -0.7806 -0.8326 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P17 mock treatment 128880.0 2800.0 0.09 94480.0 -30000.0 -0.78 -0.4902 -0.6247 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P18 mock treatment 115920.0 -10200.0 -0.31 83840.0 -40700.0 -1.06 -0.9697 -0.8797 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P19 mock treatment 134560.0 8480.0 0.26 87920.0 -36600.0 -0.95 -0.4863 -0.4932 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P20 mock treatment 146800.0 20700.0 0.64 88040.0 -36500.0 -0.95 -0.2159 -0.1887 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P21 mock treatment 117000.0 -9080.0 -0.28 93840.0 -30700.0 -0.8 -0.7623 -0.9023 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P22 mock treatment 113640.0 -12400.0 -0.39 100600.0 -23900.0 -0.62 -0.7117 -0.9737 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P23 mock treatment 99040.0 -27000.0 -0.84 108160.0 -16300.0 -0.42 -0.8927 -0.9503 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2104 P24 mock treatment 71320.0 -54800.0 -1.7 77920.0 -46600.0 -1.21 -2.0556 -0.9863 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A01 mock treatment 105520.0 -28200.0 -0.87 92560.0 -42400.0 -1.1 -1.397 -0.9933 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A02 mock treatment 140600.0 6900.0 0.21 182160.0 47200.0 1.23 1.0178 0.818 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A03 mock treatment 155680.0 22000.0 0.68 215840.0 80900.0 2.1 1.967 0.8907 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A04 mock treatment 153240.0 19500.0 0.61 202120.0 67100.0 1.74 1.6614 0.8999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A05 mock treatment 135800.0 2100.0 0.06 183000.0 48000.0 1.25 0.9281 0.7429 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A06 mock treatment 93240.0 -40500.0 -1.25 148000.0 13000.0 0.34 -0.6474 -0.4986 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A07 mock treatment 135080.0 1380.0 0.04 217000.0 82000.0 2.13 1.537 0.7211 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A08 mock treatment 117000.0 -16700.0 -0.52 209720.0 74700.0 1.94 1.0071 0.5011 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A09 mock treatment 112040.0 -21700.0 -0.67 207880.0 72900.0 1.89 0.8646 0.4303 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A10 mock treatment 120680.0 -13000.0 -0.4 209880.0 74900.0 1.95 1.0906 0.5488 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A11 mock treatment 133760.0 56.7 0.0 217960.0 83000.0 2.16 1.5257 0.7077 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A12 mock treatment 170760.0 37100.0 1.15 204200.0 69200.0 1.8 2.0835 0.9765 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A13 mock treatment 164640.0 30900.0 0.96 191680.0 56700.0 1.47 1.7194 0.9783 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A14 mock treatment 155640.0 21900.0 0.68 202680.0 67700.0 1.76 1.7243 0.9145 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A15 mock treatment 155160.0 21500.0 0.66 138480.0 3490.0 0.09 0.5343 0.7963 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A16 mock treatment 128880.0 -4820.0 -0.15 182520.0 47500.0 1.24 0.7676 0.617 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A17 mock treatment 164440.0 30700.0 0.95 167720.0 32700.0 0.85 1.2748 0.9984 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A18 mock treatment 141960.0 8260.0 0.26 182520.0 47500.0 1.24 1.0542 0.8358 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A19 mock treatment 148800.0 15100.0 0.47 208520.0 73500.0 1.91 1.6818 0.855 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A20 mock treatment 163200.0 29500.0 0.91 195480.0 60500.0 1.57 1.7577 0.9667 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A21 mock treatment 182640.0 48900.0 1.52 190680.0 55700.0 1.45 2.0954 0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A22 mock treatment 174280.0 40600.0 1.26 180120.0 45100.0 1.17 1.7182 0.9994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A23 mock treatment 123120.0 -10600.0 -0.33 118960.0 -16000.0 -0.42 -0.5263 -0.993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 A24 mock treatment 94400.0 -39300.0 -1.22 96360.0 -38600.0 -1.0 -1.5708 -0.9954 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B01 mock treatment 164480.0 30800.0 0.95 195040.0 60100.0 1.56 1.7776 0.9721 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B02 mock treatment 158760.0 25100.0 0.78 211760.0 76800.0 1.99 1.9595 0.9154 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B03 compound treatment 20440.0 -113000.0 -3.51 22280.0 -113000.0 -2.93 -4.5522 -0.996 577 HSCI1_000201 CN1C(=O)C(=C(C1=O)c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B04 compound treatment 111720.0 -22000.0 -0.68 155960.0 21000.0 0.54 -0.0963 -0.1104 614 HSCI1_000202 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c65 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B05 compound treatment 143960.0 10300.0 0.32 131720.0 -3270.0 -0.08 0.1647 0.5007 907102 HSCI1_000203 NCCCCCCNS(=O)(=O)c1cccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B06 compound treatment 164360.0 30700.0 0.95 171600.0 36600.0 0.95 1.3443 1.0 1012954 HSCI1_000204 OC(Cc1ccncc1)C(Cl)(Cl)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B07 compound treatment 29880.0 -104000.0 -3.22 72760.0 -62200.0 -1.62 -3.418 -0.9493 3176210 HSCI1_000205 CCCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B08 compound treatment 66880.0 -66800.0 -2.07 119840.0 -15100.0 -0.39 -1.7423 -0.8267 321 HSCI1_000206 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B09 compound treatment 6760.0 -127000.0 -3.93 11520.0 -123000.0 -3.21 -5.0497 -0.9949 3176211 HSCI1_000207 C[C@@H](O)[C@]1(C)CC[C@@H](O1)[C@]2(C)CC[C@@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C/C[C@@H](C)C[C@@H](C)/C(=C/C(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(=O)O)/O)O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B10 compound treatment 81640.0 -52100.0 -1.61 132920.0 -2070.0 -0.05 -1.1786 -0.7302 3103895 HSCI1_000208 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B11 mock treatment 158440.0 24700.0 0.77 153360.0 18400.0 0.48 0.8795 0.974 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B12 mock treatment 150960.0 17300.0 0.53 143120.0 8130.0 0.21 0.5275 0.9175 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B13 mock treatment 143000.0 9300.0 0.29 164120.0 29100.0 0.76 0.7389 0.9124 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B14 mock treatment 152880.0 19200.0 0.59 126000.0 -8990.0 -0.23 0.255 0.3995 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B15 compound treatment 20040.0 -114000.0 -3.52 65600.0 -69400.0 -1.8 -3.7651 -0.9516 1940 HSCI1_000209 NSC(=S)N1CCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B16 compound treatment 111200.0 -22500.0 -0.7 159920.0 24900.0 0.65 -0.0349 -0.0367 1000071 HSCI1_000210 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B17 compound treatment 129640.0 -4060.0 -0.13 183400.0 48400.0 1.26 0.8004 0.6332 3176212 HSCI1_000211 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B18 compound treatment 105760.0 -27900.0 -0.87 126760.0 -8230.0 -0.21 -0.7634 -0.856 831767 HSCI1_000212 NCCCNCCCCNCCCN 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B19 compound treatment 169080.0 35400.0 1.1 139680.0 4690.0 0.12 0.8613 0.7809 3054778 HSCI1_000213 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B20 compound treatment 142600.0 8900.0 0.28 129000.0 -5990.0 -0.16 0.0849 0.2683 2293 HSCI1_000214 CSC(=N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B21 compound treatment 148320.0 14600.0 0.45 160920.0 25900.0 0.67 0.7967 0.9813 1001920 HSCI1_000215 CNC[C@H](O)c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B22 compound treatment 160400.0 26700.0 0.83 179080.0 44100.0 1.15 1.395 0.9872 3054779 HSCI1_000216 CN/C(=N\C)/NCCC[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B23 mock treatment 143800.0 10100.0 0.31 203480.0 68500.0 1.78 1.4796 0.8189 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 B24 mock treatment 153800.0 20100.0 0.62 170520.0 35500.0 0.92 1.0931 0.9816 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C01 mock treatment 128520.0 -5180.0 -0.16 194720.0 59700.0 1.55 0.9839 0.6306 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C02 mock treatment 156120.0 22400.0 0.69 252360.0 117000.0 3.05 2.6476 0.8465 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C03 compound treatment 146760.0 13100.0 0.4 230280.0 95300.0 2.48 2.0368 0.8119 2022 HSCI1_000217 CC1(C)C(C=C(Br)Br)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C04 compound treatment 82840.0 -50900.0 -1.58 104600.0 -30400.0 -0.79 -1.6727 -0.9489 3176214 HSCI1_000218 COc1ccc2c(cc(C)c3nnc(SCC(=O)Nc4cccc(c4)C(=O)C)n32)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C05 compound treatment 62760.0 -70900.0 -2.2 81920.0 -53100.0 -1.38 -2.5293 -0.9748 3054780 HSCI1_000219 CCCCc1c([nH]c2nccnc12)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C06 compound treatment 9880.0 -124000.0 -3.84 11480.0 -124000.0 -3.21 -4.982 -0.9961 3054781 HSCI1_000220 NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+](=O)[O-])cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C07 compound treatment 64800.0 -68900.0 -2.13 53600.0 -81400.0 -2.11 -3.0049 -1.0 360 HSCI1_000221 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C08 compound treatment 28800.0 -105000.0 -3.25 30240.0 -105000.0 -2.72 -4.2228 -0.9961 2260 HSCI1_000222 Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(CO)c8c1c2c(c34)c(c65)c78 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C09 compound treatment 121160.0 -12500.0 -0.39 147960.0 13000.0 0.34 -0.0365 -0.0709 3054782 HSCI1_000223 O=c1cc(oc2c1ccc3ccccc32)N4CCOCC4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C10 compound treatment 56120.0 -77600.0 -2.4 65160.0 -69800.0 -1.81 -2.9827 -0.9904 3176215 HSCI1_000224 C1CCC(CC1)n2cnc3c(Nc4ccc(cc4)N5CCOCC5)nc(Oc6cccc7ccccc67)nc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C11 mock treatment 131720.0 -1980.0 -0.06 128080.0 -6910.0 -0.18 -0.1704 -0.898 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C12 mock treatment 171840.0 38100.0 1.18 128280.0 -6710.0 -0.17 0.7123 0.5964 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C13 mock treatment 148360.0 14700.0 0.45 134400.0 -587.0 -0.02 0.3103 0.683 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C14 mock treatment 146520.0 12800.0 0.4 129080.0 -5910.0 -0.15 0.1723 0.4046 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C15 mock treatment 150560.0 16900.0 0.52 135880.0 893.0 0.02 0.3857 0.7378 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C16 mock treatment 138080.0 4380.0 0.14 131560.0 -3430.0 -0.09 0.0329 0.203 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C17 compound treatment 144640.0 10900.0 0.34 135000.0 12.9 0.0 0.2399 0.7078 3176216 HSCI1_000225 CCCCCCCCCCCCCCCCC(=C)OOCC(COP(=O)(ON)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(=O)(O)ON)[C@H](OP(=O)(O)ON)[C@H]1O)OOC(=C)CC/C=C/C/C=C/C\C=C\C\C=C\CCCCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C18 compound treatment 85440.0 -48300.0 -1.5 135080.0 92.9 0.0 -1.0557 -0.706 907140 HSCI1_000226 NCCCCNS(=O)(=O)c1ccc2ccccc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C19 compound treatment 123240.0 -10500.0 -0.32 151440.0 16500.0 0.43 0.073 0.1361 3054783 HSCI1_000227 Nc1nc2n(cnc2c(=O)[nH]1)C3OC(COP(=O)(O)OP(=S)(O)O)[C@H](O)[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C20 compound treatment 16080.0 -118000.0 -3.64 18080.0 -117000.0 -3.04 -4.7249 -0.9959 2081802 HSCI1_000228 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)c(CN(C)C)c5cc4Cn3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C21 compound treatment 137680.0 3980.0 0.12 151360.0 16400.0 0.43 0.3879 0.8759 3176218 HSCI1_000229 Nc1nc2n(C3OC4COP(O)(O)OC4C3O)c(Br)nc2c(=O)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C22 compound treatment 70000.0 -63700.0 -1.97 66840.0 -68100.0 -1.77 -2.6477 -0.9985 3054784 HSCI1_000230 Nc1nc(Cl)nc2n(cnc12)C3C[C@@H](O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C23 compound treatment 28800.0 -105000.0 -3.25 43200.0 -91800.0 -2.38 -3.9847 -0.9884 1338 HSCI1_000231 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 C24 mock treatment 132040.0 -1660.0 -0.05 172720.0 37700.0 0.98 0.6568 0.669 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D01 mock treatment 122320.0 -11400.0 -0.35 159840.0 24900.0 0.65 0.2072 0.2816 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D02 mock treatment 146600.0 12900.0 0.4 176160.0 41200.0 1.07 1.039 0.9098 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D03 compound treatment 7800.0 -126000.0 -3.9 10160.0 -125000.0 -3.24 -5.0519 -0.9958 3176219 HSCI1_000232 O/N=C/1\C(=C/2\C(=O)Nc3cc(Br)ccc23)\Nc4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D04 compound treatment 75560.0 -58100.0 -1.8 78560.0 -56400.0 -1.47 -2.3106 -0.9948 3054785 HSCI1_000233 O=C1NC(=O)c2c1ccc(Nc3ccccc3)c2Nc4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D05 compound treatment 8080.0 -126000.0 -3.89 9720.0 -125000.0 -3.25 -5.0538 -0.996 1277018 HSCI1_000234 COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D06 compound treatment 36320.0 -97400.0 -3.02 27720.0 -107000.0 -2.79 -4.1044 -0.9992 1919 HSCI1_000235 CCCCCc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D07 compound treatment 31240.0 -102000.0 -3.17 65880.0 -69100.0 -1.8 -3.5146 -0.9636 3176221 HSCI1_000236 C1C[C@H](N/C/2=N/CCCCCCCCCCC2)[C@@H](C1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D08 compound treatment 175720.0 42000.0 1.3 185920.0 50900.0 1.32 1.8563 1.0 3054786 HSCI1_000237 OCC1OC([C@@H](O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D09 compound treatment 9520.0 -124000.0 -3.85 12440.0 -123000.0 -3.18 -4.9723 -0.9956 3176222 HSCI1_000238 COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D10 compound treatment 162760.0 29100.0 0.9 143840.0 8850.0 0.23 0.7993 0.8601 407 HSCI1_000239 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D11 mock treatment 150960.0 17300.0 0.53 135200.0 213.0 0.01 0.382 0.7144 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D12 mock treatment 141600.0 7900.0 0.24 127840.0 -7150.0 -0.19 0.0417 0.1358 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D13 mock treatment 155800.0 22100.0 0.68 136000.0 1010.0 0.03 0.5027 0.7337 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D14 mock treatment 166320.0 32600.0 1.01 163000.0 28000.0 0.73 1.2293 0.987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D15 mock treatment 136560.0 2860.0 0.09 158120.0 23100.0 0.6 0.4876 0.8026 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D16 mock treatment 141000.0 7300.0 0.23 139680.0 4690.0 0.12 0.2461 0.958 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D17 compound treatment 114720.0 -19000.0 -0.59 139040.0 4050.0 0.11 -0.3414 -0.5714 3054787 HSCI1_000240 N/N=C(/N)\NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D18 compound treatment 123160.0 -10500.0 -0.33 139800.0 4810.0 0.13 -0.1426 -0.4076 907294 HSCI1_000241 CN(C)C(=N)NCCC[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D19 compound treatment 133400.0 -303.0 -0.01 190200.0 55200.0 1.43 1.0078 0.7025 3176223 HSCI1_000242 CSC(=N)NCCC[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D20 compound treatment 138880.0 5180.0 0.16 147440.0 12500.0 0.32 0.3422 0.9476 3054789 HSCI1_000243 CNC(=N)NCCC[C@@H](N)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D21 compound treatment 128240.0 -5460.0 -0.17 134880.0 -107.0 0.0 -0.1217 -0.7186 3176224 HSCI1_000244 OP(=O)(O)C(Cl)(Cl)P(=O)(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D22 compound treatment 137360.0 3660.0 0.11 151200.0 16200.0 0.42 0.378 0.8665 3176225 HSCI1_000245 CNC(=N)NCCC[C@H](N)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D23 compound treatment 137080.0 3380.0 0.1 156560.0 21600.0 0.56 0.4703 0.8248 2215 HSCI1_000246 CCCNC(=N)NCCCC(N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 D24 mock treatment 105440.0 -28300.0 -0.88 145880.0 10900.0 0.28 -0.4191 -0.4554 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E01 mock treatment 111120.0 -22600.0 -0.7 167560.0 32600.0 0.85 0.1037 0.0944 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E02 mock treatment 147920.0 14200.0 0.44 160560.0 25600.0 0.66 0.7813 0.9801 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E03 mock treatment 131440.0 -2260.0 -0.07 145000.0 10000.0 0.26 0.1344 0.4987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E04 mock treatment 132240.0 -1460.0 -0.05 156760.0 21800.0 0.57 0.368 0.6484 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E05 compound treatment 116800.0 -16900.0 -0.52 147680.0 12700.0 0.33 -0.1371 -0.2216 3176226 HSCI1_000247 CCCCc1c([nH]c2nccnc12)c3ccc(OC)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E06 compound treatment 6920.0 -127000.0 -3.93 7560.0 -127000.0 -3.31 -5.1189 -0.9964 2371 HSCI1_000248 CCCCCCCCNC(=O)C(Cc1ccc(OCc2ccncc2)cc1)NC(=O)C3CCC(CN)CC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E07 compound treatment 6080.0 -128000.0 -3.95 6880.0 -128000.0 -3.33 -5.1498 -0.9963 1989 HSCI1_000249 Clc1[nH]c2ccccc2c1/C=C\3/C(=O)Nc4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E08 compound treatment 6880.0 -127000.0 -3.93 7760.0 -127000.0 -3.31 -5.1161 -0.9963 1416171 HSCI1_000250 OC(CN1CCNCC1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E09 mock treatment 130920.0 -2780.0 -0.09 140080.0 5090.0 0.13 0.0326 0.2063 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E10 mock treatment 133400.0 -303.0 -0.01 140920.0 5930.0 0.15 0.1024 0.6628 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E11 compound treatment 117320.0 -16400.0 -0.51 106760.0 -28200.0 -0.73 -0.8776 -0.9838 663 HSCI1_000251 Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E12 compound treatment 16360.0 -117000.0 -3.64 14000.0 -121000.0 -3.14 -4.7938 -0.9974 1000089 HSCI1_000252 COC1C(C)OC(OC2CC(C)(O)C(C(=O)OC)c3cc4C(=O)c5c6OC7OC(C)(C(O)C(C7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)C(OC)C1(C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E13 compound treatment 152680.0 19000.0 0.59 134320.0 -667.0 -0.02 0.4035 0.686 3054791 HSCI1_000253 Nc1nc2n(cnc2c(=O)[nH]1)C3OC4COP(O)(O)OC4C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E14 compound treatment 138480.0 4780.0 0.15 128720.0 -6270.0 -0.16 -0.0105 -0.0477 3176276 HSCI1_000254 NCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-])C(=O)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E15 mock treatment 137160.0 3460.0 0.11 142160.0 7170.0 0.19 0.2075 0.9654 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E16 mock treatment 147040.0 13300.0 0.41 130800.0 -4190.0 -0.11 0.2153 0.5038 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E17 mock treatment 136920.0 3220.0 0.1 129240.0 -5750.0 -0.15 -0.0351 -0.1956 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E18 mock treatment 156720.0 23000.0 0.71 131520.0 -3470.0 -0.09 0.4406 0.6129 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E19 compound treatment 132560.0 -1140.0 -0.04 139160.0 4170.0 0.11 0.0516 0.4525 1000095 HSCI1_000255 CC(O)C(O)[C@H]1CNc2nc(N)[nH]c(=O)c2N1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E20 compound treatment 136840.0 3140.0 0.1 149400.0 14400.0 0.37 0.3335 0.8621 3054834 HSCI1_000256 NCCNC[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E21 compound treatment 148520.0 14800.0 0.46 145840.0 10900.0 0.28 0.524 0.9726 423 HSCI1_000257 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E22 compound treatment 126720.0 -6980.0 -0.22 162840.0 27900.0 0.72 0.3587 0.4749 2114444 HSCI1_000258 O=c1n(CCN2CCCCC2)c(=O)c3ccc4c5ccc6c(=O)n(CCN7CCCCC7)c(=O)c8ccc(c9ccc1c3c94)c5c86 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E23 compound treatment 135280.0 1580.0 0.05 191520.0 56500.0 1.47 1.0732 0.7302 832002 HSCI1_000259 CC(=N)NCCC[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 E24 mock treatment 104400.0 -29300.0 -0.91 169520.0 34500.0 0.9 -0.0076 -0.0059 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F01 mock treatment 118560.0 -15100.0 -0.47 186200.0 51200.0 1.33 0.6091 0.4317 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F02 mock treatment 139720.0 6020.0 0.19 166880.0 31900.0 0.83 0.7178 0.8451 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F03 mock treatment 144040.0 10300.0 0.32 160920.0 25900.0 0.67 0.7029 0.9422 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F04 mock treatment 152640.0 18900.0 0.59 152320.0 17300.0 0.45 0.7333 0.9915 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F05 compound treatment 8680.0 -125000.0 -3.87 9640.0 -125000.0 -3.26 -5.0421 -0.9963 3176278 HSCI1_000260 CC(=O)O/N=C/1\C(=C/2\C(=O)Nc3cc(Br)ccc23)\Nc4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F06 compound treatment 148080.0 14400.0 0.45 155480.0 20500.0 0.53 0.6915 0.9961 1505 HSCI1_000261 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F07 compound treatment 21320.0 -112000.0 -3.48 21480.0 -114000.0 -2.95 -4.5477 -0.9966 3054836 HSCI1_000262 COc1ccc(CNc2nc(nc3n(cnc23)C(C)C)N(CCO)CCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F08 compound treatment 11360.0 -122000.0 -3.79 12120.0 -123000.0 -3.19 -4.9379 -0.9963 1980 HSCI1_000263 CC1(C2CCC(O2)C1(C)C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F09 mock treatment 137120.0 3420.0 0.11 143920.0 8930.0 0.23 0.239 0.9368 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F10 mock treatment 143000.0 9300.0 0.29 136320.0 1330.0 0.03 0.2282 0.7865 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F11 compound treatment 83800.0 -49900.0 -1.55 88960.0 -46000.0 -1.2 -1.939 -0.9919 832084 HSCI1_000264 NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c4nc[nH]c4n2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F12 compound treatment 156160.0 22500.0 0.7 126640.0 -8350.0 -0.22 0.3387 0.4647 445 HSCI1_000265 NC(=O)c1cccc(N)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F13 compound treatment 138880.0 5180.0 0.16 115840.0 -19100.0 -0.5 -0.2384 -0.456 2194 HSCI1_000266 OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(c3)[N+](=O)[O-])ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F14 compound treatment 145240.0 11500.0 0.36 138200.0 3210.0 0.08 0.3118 0.8494 2025 HSCI1_000267 NCCCC(N)(C(F)F)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F15 mock treatment 139680.0 5980.0 0.19 128320.0 -6670.0 -0.17 0.0085 0.0333 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F16 mock treatment 150040.0 16300.0 0.51 132920.0 -2070.0 -0.05 0.3199 0.6286 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F17 mock treatment 139320.0 5620.0 0.17 133760.0 -1230.0 -0.03 0.1005 0.5681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F18 mock treatment 136880.0 3180.0 0.1 131400.0 -3590.0 -0.09 0.0037 0.0273 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F19 compound treatment 111120.0 -22600.0 -0.7 117640.0 -17300.0 -0.45 -0.8135 -0.9774 2259 HSCI1_000268 CN1CCc2cc3OCOc3cc2C(=O)Cc4ccc5OCOc5c4C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F20 compound treatment 151680.0 18000.0 0.56 130840.0 -4150.0 -0.11 0.3177 0.5599 2674 HSCI1_000269 N[C@@H](CCC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F21 compound treatment 91680.0 -42000.0 -1.3 103200.0 -31800.0 -0.83 -1.5047 -0.9759 3176279 HSCI1_000270 CC[C@]1(O)C[C@H]2CN(C1)CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)[C@@H]7[C@@]86CCN9CC=C[C@@](CC)([C@H]98)[C@@H](OC(=O)C)[C@]7(O)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F22 compound treatment 120240.0 -13500.0 -0.42 157120.0 22100.0 0.58 0.1117 0.1572 2129 HSCI1_000271 OCC(O)C1OC(=O)C(=C1O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F23 compound treatment 10080.0 -124000.0 -3.83 12360.0 -123000.0 -3.19 -4.9615 -0.9958 1000078 HSCI1_000272 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 F24 mock treatment 96200.0 -37500.0 -1.16 217800.0 82800.0 2.15 0.6998 0.2862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G01 mock treatment 141600.0 7900.0 0.24 149600.0 14600.0 0.38 0.4415 0.9774 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G02 compound treatment 11800.0 -122000.0 -3.78 18280.0 -117000.0 -3.03 -4.815 -0.9941 25 HSCI1_000273 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G03 mock treatment 135640.0 1940.0 0.06 138680.0 3690.0 0.1 0.1103 0.9745 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G04 mock treatment 140680.0 6980.0 0.22 145760.0 10800.0 0.28 0.3508 0.9918 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G05 mock treatment 135600.0 1900.0 0.06 131800.0 -3190.0 -0.08 -0.017 -0.1674 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G06 mock treatment 143960.0 10300.0 0.32 147400.0 12400.0 0.32 0.4528 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G07 compound treatment 8880.0 -125000.0 -3.87 9160.0 -126000.0 -3.27 -5.0466 -0.9965 3054838 HSCI1_000274 CC(C)(c1ccc(NS(=O)(=O)C(F)(F)F)cc1)c2ccc(cc2)C(C)(C)c3cccc(NS(=O)(=O)C(F)(F)F)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G08 compound treatment 148160.0 14500.0 0.45 129480.0 -5510.0 -0.14 0.2156 0.4584 546 HSCI1_000275 Cc1ncc2ccccc2c1C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G09 compound treatment 23160.0 -111000.0 -3.43 13480.0 -122000.0 -3.16 -4.6543 -0.9992 1947905 HSCI1_000276 Clc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G10 compound treatment 146640.0 12900.0 0.4 129880.0 -5110.0 -0.13 0.1896 0.4491 636 HSCI1_000277 C/C(=C(\C#N)/C(=O)Nc1cccc(F)c1)/O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G11 compound treatment 22400.0 -111000.0 -3.45 27720.0 -107000.0 -2.79 -4.4094 -0.9944 3176281 HSCI1_000278 COc1ccc(CNC(=O)Nc2ncc(s2)[N+](=O)[O-])cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G12 compound treatment 153880.0 20200.0 0.63 128200.0 -6790.0 -0.18 0.3174 0.4886 3054840 HSCI1_000279 CC1OC(C[C@H]1O)n2cnc3c(N)ncnc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G13 compound treatment 11040.0 -123000.0 -3.8 11880.0 -123000.0 -3.2 -4.9493 -0.9963 2319 HSCI1_000280 CN(C)CC1Cc2ccccc2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G14 compound treatment 137960.0 4260.0 0.13 108600.0 -26400.0 -0.69 -0.3915 -0.5608 3176282 HSCI1_000281 N[C@@H](CCN/C(=N/O)/N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G15 compound treatment 135400.0 1700.0 0.05 140920.0 5930.0 0.15 0.1462 0.8975 2145 HSCI1_000282 NC(=N)NCCS 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G16 compound treatment 148400.0 14700.0 0.46 126200.0 -8790.0 -0.23 0.1606 0.3152 3583 HSCI1_000283 Cn1cc(NC(=O)c2cc(NC(=O)CNC(=N)N)cn2C)cc1C(=O)NCCC(=N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G17 mock treatment 134960.0 1260.0 0.04 123000.0 -12000.0 -0.31 -0.1927 -0.6139 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G18 mock treatment 133760.0 56.7 0.0 133360.0 -1630.0 -0.04 -0.0287 -0.6771 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G19 mock treatment 148760.0 15100.0 0.47 155680.0 20700.0 0.54 0.7101 0.9975 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G20 mock treatment 123720.0 -9980.0 -0.31 126520.0 -8470.0 -0.22 -0.3743 -0.9861 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G21 compound treatment 142400.0 8700.0 0.27 141480.0 6490.0 0.17 0.3098 0.9746 1030173 HSCI1_000284 NC(=N)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G22 compound treatment 16240.0 -117000.0 -3.64 20680.0 -114000.0 -2.97 -4.6737 -0.9949 3176283 HSCI1_000285 COc1cc(ccc1[n+]2nc(nn2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)c5ccc(c(OC)c5)[n+]6nc(nn6c7ccc(cc7)[N+](=O)[O-])c8ccccc8 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G23 compound treatment 127640.0 -6060.0 -0.19 146880.0 11900.0 0.31 0.0857 0.2369 469 HSCI1_000286 CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 G24 mock treatment 111360.0 -22300.0 -0.69 147360.0 12400.0 0.32 -0.2622 -0.3435 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H01 mock treatment 126080.0 -7620.0 -0.24 123760.0 -11200.0 -0.29 -0.3733 -0.9945 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H02 compound treatment 133240.0 -463.0 -0.01 152360.0 17400.0 0.45 0.309 0.6843 1594 HSCI1_000287 N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H03 mock treatment 139800.0 6100.0 0.19 137960.0 2970.0 0.08 0.1882 0.9221 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H04 mock treatment 144520.0 10800.0 0.34 144280.0 9290.0 0.24 0.4077 0.9871 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H05 mock treatment 177600.0 43900.0 1.36 151760.0 16800.0 0.44 1.2699 0.8891 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H06 mock treatment 145840.0 12100.0 0.38 147400.0 12400.0 0.32 0.494 0.9971 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H07 compound treatment 26360.0 -107000.0 -3.33 19200.0 -116000.0 -3.01 -4.4791 -0.9987 3054842 HSCI1_000288 CSc1nc(c([nH]1)c2ccnc(NC(C)c3ccccc3)c2)c4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H08 compound treatment 198920.0 65200.0 2.02 191560.0 56600.0 1.47 2.4682 0.9878 1961 HSCI1_000289 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H09 compound treatment 31680.0 -102000.0 -3.16 27520.0 -107000.0 -2.79 -4.2097 -0.9981 572 HSCI1_000290 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H10 compound treatment 134120.0 417.0 0.01 131560.0 -3430.0 -0.09 -0.0538 -0.5983 1907755 HSCI1_000291 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H11 compound treatment 33080.0 -101000.0 -3.12 39600.0 -95400.0 -2.48 -3.9571 -0.9935 574 HSCI1_000292 NCCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H12 compound treatment 79160.0 -54500.0 -1.69 85520.0 -49500.0 -1.29 -2.1038 -0.9909 3176284 HSCI1_000293 COc1cc2C3CC[C@]4(C)[C@@H](O)CCC4C3CCc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H13 compound treatment 129480.0 -4220.0 -0.13 137440.0 2450.0 0.06 -0.0475 -0.3261 2195 HSCI1_000294 OS(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c3)ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H14 compound treatment 124760.0 -8940.0 -0.28 121480.0 -13500.0 -0.35 -0.4441 -0.9932 1714 HSCI1_000295 CN(C)C(=N)NC(=N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H15 compound treatment 127440.0 -6260.0 -0.19 127920.0 -7070.0 -0.18 -0.2671 -0.9996 2197 HSCI1_000296 OS(=O)(=O)c1ccc(NC(=O)c2cc(NC(=O)Nc3cc(cc(c3)C(=O)Nc4ccc(cc4S(=O)(=O)O)S(=O)(=O)O)C(=O)Nc5ccc(cc5S(=O)(=O)O)S(=O)(=O)O)cc(c2)C(=O)Nc6ccc(cc6S(=O)(=O)O)S(=O)(=O)O)c(c1)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H16 compound treatment 132160.0 -1540.0 -0.05 159120.0 24100.0 0.63 0.4096 0.6513 3054849 HSCI1_000297 CCNC(=N)NCCC[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H17 mock treatment 146600.0 12900.0 0.4 128080.0 -6910.0 -0.18 0.1557 0.3553 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H18 mock treatment 140760.0 7060.0 0.22 142520.0 7530.0 0.2 0.293 0.9985 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H19 mock treatment 142680.0 8980.0 0.28 144080.0 9090.0 0.24 0.3637 0.9967 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H20 mock treatment 134520.0 817.0 0.03 142440.0 7450.0 0.19 0.1548 0.7928 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H21 compound treatment 11360.0 -122000.0 -3.79 11160.0 -124000.0 -3.22 -4.9555 -0.9967 3054896 HSCI1_000298 NC(=O)c1cn(C2OC(CO)[C@H](O)[C@@H]2O)c3ncnc(N)c13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H22 compound treatment 145200.0 11500.0 0.36 132160.0 -2830.0 -0.07 0.1999 0.5497 2063 HSCI1_000299 CCOC(=O)c1cnc2n(CC)ncc2c1NN=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H23 compound treatment 100120.0 -33600.0 -1.04 116960.0 -18000.0 -0.47 -1.067 -0.935 606 HSCI1_000300 CNCCNS(=O)(=O)c1cccc2cnccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 H24 mock treatment 114560.0 -19100.0 -0.59 124240.0 -10700.0 -0.28 -0.6169 -0.9409 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I01 mock treatment 111200.0 -22500.0 -0.7 119480.0 -15500.0 -0.4 -0.7779 -0.966 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I02 compound treatment 137680.0 3980.0 0.12 137120.0 2130.0 0.06 0.1263 0.9349 662 HSCI1_000301 Cc1nc(c(o1)c2ccncc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I03 compound treatment 79760.0 -53900.0 -1.67 77960.0 -57000.0 -1.48 -2.2296 -0.9982 3054901 HSCI1_000302 Clc1cc(Cl)c(NC(=O)Nc2ccncc2)c(Cl)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I04 compound treatment 83800.0 -49900.0 -1.55 74840.0 -60100.0 -1.56 -2.1984 -1.0 2110413 HSCI1_000303 Cc1cc(C)c(/C=C/2\C(=O)Nc3ccccc23)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I05 mock treatment 119760.0 -13900.0 -0.43 136720.0 1730.0 0.05 -0.2736 -0.63 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I06 mock treatment 142080.0 8380.0 0.26 132160.0 -2830.0 -0.07 0.1316 0.4878 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I07 mock treatment 147960.0 14300.0 0.44 138720.0 3730.0 0.1 0.3809 0.8423 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I08 mock treatment 126960.0 -6740.0 -0.21 138240.0 3250.0 0.08 -0.088 -0.3903 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I09 compound treatment 141040.0 7340.0 0.23 139080.0 4090.0 0.11 0.2359 0.9401 2023 HSCI1_000304 CCCCn1c(=O)n(CCCC)c2ncn(CC(=O)C)c2c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I10 compound treatment 97040.0 -36700.0 -1.14 107600.0 -27400.0 -0.71 -1.3064 -0.9746 2196 HSCI1_000305 OS(=O)(=O)c1cc(c2c(NC(=O)c3ccc(NC(=O)c4ccc(NC(=O)Nc5ccc(cc5)C(=O)Nc6ccc(cc6)C(=O)Nc7ccc(c8cc(cc(c78)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)cc4)cc3)ccc(c2c1)S(=O)(=O)O)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I11 compound treatment 75080.0 -58600.0 -1.82 92240.0 -42700.0 -1.11 -2.0698 -0.9721 3054905 HSCI1_000306 Oc1ccc(cc1O)C(=O)/C(=C/c2ccc3oc(=O)[nH]c3c2)/C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I12 compound treatment 106680.0 -27000.0 -0.84 117200.0 -17800.0 -0.46 -0.9189 -0.9608 3054907 HSCI1_000307 Cc1nc2cc3nc(cnc3cc2n1C)c4cccs4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I13 compound treatment 150640.0 16900.0 0.52 141240.0 6250.0 0.16 0.486 0.8846 3479224 HSCI1_000308 CC(=N)NCCCCC(N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I14 compound treatment 26280.0 -107000.0 -3.33 25280.0 -110000.0 -2.85 -4.3692 -0.997 2061 HSCI1_000309 Oc1cc(c2cc(ccc2c1N=Nc3ccc4ccccc4c3O)[N+](=O)[O-])S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I15 compound treatment 134880.0 1180.0 0.04 131040.0 -3950.0 -0.1 -0.0467 -0.4294 2087 HSCI1_000310 NC(CCC(=O)NC(CSN=O)C(=O)NCC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I16 compound treatment 125240.0 -8460.0 -0.26 127400.0 -7590.0 -0.2 -0.3248 -0.9901 1870 HSCI1_000311 NC(=N)SCCc1cccc(CCSC(=N)N)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I17 compound treatment 72280.0 -61400.0 -1.9 73760.0 -61200.0 -1.59 -2.4706 -0.996 2408 HSCI1_000312 NCCC(O)(P(=O)(O)O)P(=O)(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I18 compound treatment 136000.0 2300.0 0.07 136720.0 1730.0 0.05 0.0822 0.9756 3054955 HSCI1_000313 Cc1ccc(cc1)S(=O)(=O)N[C@H](CCCCN)C(=O)CCl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I19 mock treatment 144920.0 11200.0 0.35 147440.0 12500.0 0.32 0.4745 0.9994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I20 mock treatment 135120.0 1420.0 0.04 154640.0 19700.0 0.51 0.3921 0.7651 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I21 mock treatment 140320.0 6620.0 0.21 137720.0 2730.0 0.07 0.1952 0.8996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I22 mock treatment 135520.0 1820.0 0.06 156960.0 22000.0 0.57 0.4435 0.7731 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I23 compound treatment 156240.0 22500.0 0.7 149680.0 14700.0 0.38 0.7637 0.9596 1956 HSCI1_000314 N[C@H](CSCCB(O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 I24 mock treatment 102960.0 -30700.0 -0.95 123600.0 -11400.0 -0.3 -0.8828 -0.885 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J01 mock treatment 125880.0 -7820.0 -0.24 118360.0 -16600.0 -0.43 -0.4769 -0.9627 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J02 compound treatment 60160.0 -73500.0 -2.28 57000.0 -78000.0 -2.03 -3.0441 -0.9983 1005830 HSCI1_000315 Cc1cc(ccc1N=Nc2cc(c3ccccc3c2N)S(=O)(=O)O)c4ccc(N=Nc5cc(c6ccccc6c5N)S(=O)(=O)O)c(C)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J03 compound treatment 27560.0 -106000.0 -3.29 20240.0 -115000.0 -2.98 -4.4337 -0.9988 573 HSCI1_000316 CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J04 compound treatment 7120.0 -127000.0 -3.92 6400.0 -129000.0 -3.34 -5.1358 -0.9968 1038990 HSCI1_000317 FC(F)(F)c1ccc2Sc3ccccc3N(CCCN4CCN(CCCl)CC4)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J05 mock treatment 136000.0 2300.0 0.07 133080.0 -1910.0 -0.05 0.0153 0.1762 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J06 mock treatment 138480.0 4780.0 0.15 158400.0 23400.0 0.61 0.5348 0.8542 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J07 mock treatment 135960.0 2260.0 0.07 137160.0 2170.0 0.06 0.0894 0.9944 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J08 mock treatment 135400.0 1700.0 0.05 142600.0 7610.0 0.2 0.177 0.865 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J09 compound treatment 68520.0 -65200.0 -2.02 54160.0 -80800.0 -2.1 -2.9131 -0.9998 3054961 HSCI1_000318 OCc1cc2ncnc(Nc3cc(Br)c(O)c(Br)c3)c2cc1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J10 compound treatment 9120.0 -125000.0 -3.86 9640.0 -125000.0 -3.26 -5.0325 -0.9964 1979 HSCI1_000319 Clc1ccc(cc1)C(c2ccc(Cl)cc2)[n+]3ccn(CC(OCc4ccc(Cl)cc4Cl)c5ccc(Cl)cc5Cl)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J11 compound treatment 8880.0 -125000.0 -3.87 8720.0 -126000.0 -3.28 -5.0547 -0.9966 580 HSCI1_000320 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCN)c4ccccc34)c5ccccc15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J12 compound treatment 138440.0 4740.0 0.15 129320.0 -5670.0 -0.15 -3.0E-4 -0.0016 3054964 HSCI1_000321 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CCC[C@]2(C)C3C(=O)C[C@@](C)(O[C@]13C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J13 compound treatment 20760.0 -113000.0 -3.5 18760.0 -116000.0 -3.02 -4.6099 -0.9973 907101 HSCI1_000322 NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J14 compound treatment 135240.0 1540.0 0.05 133360.0 -1630.0 -0.04 0.0038 0.0593 3176334 HSCI1_000323 CC(C)[C@@]1(C)[C@@H]([C@H](OO)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@@]1(C)[C@@]5(O)C[C@@]3(C)[C@@]6(O)CCC(=C)[C@@H](O)[C@]46O5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J15 compound treatment 155480.0 21800.0 0.67 135040.0 52.9 0.0 0.4781 0.7085 3054966 HSCI1_000324 C[C@@H]1CNCCCN1S(=O)(=O)c2cccc3cncc(C)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J16 compound treatment 153400.0 19700.0 0.61 128360.0 -6630.0 -0.17 0.3098 0.4885 3176335 HSCI1_000325 CN1CCN(CCCC(=O)O[C@H]2[C@@H](O)[C@H]3C(C)(C)CC[C@H](O)[C@]3(C)[C@@]4(O)C(=O)C[C@@](C)(O[C@]24C)C=C)CC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J17 compound treatment 13560.0 -120000.0 -3.72 12280.0 -123000.0 -3.19 -4.8867 -0.997 1049343 HSCI1_000326 CCC(C)C1NC(=O)C(NC(=O)c2c(N)c(=O)c(C)c3oc4c(C)ccc(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J18 compound treatment 135840.0 2140.0 0.07 122280.0 -12700.0 -0.33 -0.1866 -0.5543 3054969 HSCI1_000327 C[C@@]12CCC(=O)C=C2CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@@]4(O)C[C@H](O)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J19 mock treatment 141160.0 7460.0 0.23 140800.0 5810.0 0.15 0.2702 0.9788 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J20 mock treatment 133640.0 -63.3 0.0 133600.0 -1390.0 -0.04 -0.0269 -0.7445 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J21 mock treatment 137040.0 3340.0 0.1 135720.0 733.0 0.02 0.0866 0.8235 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J22 mock treatment 131640.0 -2060.0 -0.06 126760.0 -8230.0 -0.21 -0.1964 -0.8801 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J23 compound treatment 114280.0 -19400.0 -0.6 103960.0 -31000.0 -0.81 -0.9956 -0.9896 3054970 HSCI1_000328 NC(=NCCSSCCN=C(N)N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 J24 mock treatment 120160.0 -13500.0 -0.42 147800.0 12800.0 0.33 -0.0613 -0.1145 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K01 mock treatment 130880.0 -2820.0 -0.09 100960.0 -34000.0 -0.88 -0.687 -0.7733 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K02 compound treatment 90440.0 -43300.0 -1.34 77320.0 -57700.0 -1.5 -2.0074 -0.9985 637 HSCI1_000329 C/C(=C(\C#N)/C(=O)Nc1ccc(OC(F)(F)F)cc1)/O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K03 compound treatment 77960.0 -55700.0 -1.73 41800.0 -93200.0 -2.42 -2.9334 -0.9863 391 HSCI1_000330 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K04 compound treatment 6360.0 -127000.0 -3.95 4120.0 -131000.0 -3.4 -5.1944 -0.9973 3055003 HSCI1_000331 O=C1c2ccccc2-[n+]3ccc4c5ccccc5[nH]c4c13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K05 compound treatment 76760.0 -56900.0 -1.76 25520.0 -109000.0 -2.84 -3.2588 -0.9736 3055004 HSCI1_000332 Fc1ccc(cc1)C(=O)/C=C/2\C(=O)Nc3ccc(Br)cc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K06 compound treatment 8520.0 -125000.0 -3.88 7840.0 -127000.0 -3.3 -5.0787 -0.9968 3176336 HSCI1_000333 CC(C)(C)C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c3ccccc32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K07 mock treatment 116800.0 -16900.0 -0.52 123040.0 -11900.0 -0.31 -0.5898 -0.9688 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K08 mock treatment 134440.0 737.0 0.02 126760.0 -8230.0 -0.21 -0.135 -0.628 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K09 mock treatment 127200.0 -6500.0 -0.2 152760.0 17800.0 0.46 0.1841 0.3653 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K10 mock treatment 128120.0 -5580.0 -0.17 134280.0 -707.0 -0.02 -0.1353 -0.7778 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K11 compound treatment 44960.0 -88700.0 -2.75 45440.0 -89500.0 -2.33 -3.5895 -0.9965 3055006 HSCI1_000334 COc1cccc(c1)c2cc(NCc3ccc4OCOc4c3)nc(N)n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K12 compound treatment 125520.0 -8180.0 -0.25 130920.0 -4070.0 -0.11 -0.254 -0.9247 3176337 HSCI1_000335 COc1ccc(cc1)c2cnc3c(cnn3c2)c4ccsc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K13 compound treatment 39760.0 -93900.0 -2.91 35240.0 -99700.0 -2.59 -3.8909 -0.9983 3055009 HSCI1_000336 CC1=C(O)C(=O)[C@H]2O[C@H]2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K14 compound treatment 127520.0 -6180.0 -0.19 119480.0 -15500.0 -0.4 -0.4204 -0.9422 1709 HSCI1_000337 NCCCC(O)(P(=O)(O)O)P(=O)(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K15 mock treatment 140920.0 7220.0 0.22 139920.0 4930.0 0.13 0.2487 0.9651 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K16 mock treatment 143560.0 9860.0 0.31 126960.0 -8030.0 -0.21 0.0685 0.1852 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K17 compound treatment 10880.0 -123000.0 -3.81 8960.0 -126000.0 -3.27 -5.0064 -0.9972 3176338 HSCI1_000338 CCCCCCCCCCCCCCCCOCC(COCC(F)(F)F)OP(=O)(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K18 compound treatment 131400.0 -2300.0 -0.07 144080.0 9090.0 0.24 0.1166 0.4724 1932 HSCI1_000339 OP(=O)(O)Oc1cccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K19 compound treatment 122680.0 -11000.0 -0.34 112800.0 -22200.0 -0.58 -0.6491 -0.9688 95 HSCI1_000340 CCCCCC(O)/C=C/C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K20 compound treatment 11080.0 -123000.0 -3.8 9440.0 -126000.0 -3.26 -4.9932 -0.9971 3176339 HSCI1_000341 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)C[C@H](O)C3=C)\CCC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K21 mock treatment 149560.0 15900.0 0.49 136360.0 1370.0 0.04 0.3726 0.7565 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K22 mock treatment 122360.0 -11300.0 -0.35 101360.0 -33600.0 -0.87 -0.8663 -0.9199 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K23 mock treatment 130800.0 -2900.0 -0.09 123840.0 -11100.0 -0.29 -0.2684 -0.885 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 K24 mock treatment 129960.0 -3740.0 -0.12 134800.0 -187.0 0.0 -0.0854 -0.7361 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L01 mock treatment 130480.0 -3220.0 -0.1 109840.0 -25100.0 -0.65 -0.5326 -0.8058 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L02 compound treatment 21760.0 -112000.0 -3.47 15480.0 -120000.0 -3.11 -4.6483 -0.9985 594 HSCI1_000342 Cc1nc2sccn2c(=O)c1CCN3CCC(=C(c4ccccc4)c5ccc(F)cc5)CC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L03 compound treatment 5320.0 -128000.0 -3.98 3960.0 -131000.0 -3.4 -5.2201 -0.997 581 HSCI1_000343 Cn1cc(C2=C(C(=O)NC2=O)c3c4CC(CN)CCn4c5ccccc35)c6ccccc16 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L04 compound treatment 32640.0 -101000.0 -3.13 10920.0 -124000.0 -3.22 -4.4937 -0.9999 1002019 HSCI1_000344 COc1ccc2C3CC[C@]4(C)[C@H](CCC4C3CCc2c1)NCCCCCCN5C(=O)C=CC5=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L05 compound treatment 46400.0 -87300.0 -2.71 32000.0 -103000.0 -2.68 -3.8049 -1.0 3055016 HSCI1_000345 COc1cc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(Oc5ccccc5)cc4)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L06 compound treatment 12640.0 -121000.0 -3.75 8720.0 -126000.0 -3.28 -4.9723 -0.9978 2348 HSCI1_000346 COc1ccc2C3CC[C@]4(C)[C@H](CCC4C3CCc2c1)NCCCCCCN5C(=O)CCC5=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L07 mock treatment 124560.0 -9140.0 -0.28 131600.0 -3390.0 -0.09 -0.2626 -0.885 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L08 mock treatment 112000.0 -21700.0 -0.67 125120.0 -9870.0 -0.26 -0.6568 -0.9126 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L09 mock treatment 119160.0 -14500.0 -0.45 126160.0 -8830.0 -0.23 -0.4808 -0.9509 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L10 mock treatment 124120.0 -9580.0 -0.3 122160.0 -12800.0 -0.33 -0.4456 -0.9983 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L11 compound treatment 10120.0 -124000.0 -3.83 9200.0 -126000.0 -3.27 -5.0187 -0.9969 582 HSCI1_000347 CN(C)CC1CCn2c(C1)c(C3=C(C(=O)NC3=O)c4cn(C)c5ccccc45)c6ccccc26 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L12 compound treatment 14840.0 -119000.0 -3.68 13000.0 -122000.0 -3.17 -4.8454 -0.9972 595 HSCI1_000348 Fc1ccc(cc1)C(=C2CCN(CCn3c(=O)c4ccccc4[nH]c3=S)CC2)c5ccc(F)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L13 compound treatment 146000.0 12300.0 0.38 120680.0 -14300.0 -0.37 0.0066 0.0123 3176385 HSCI1_000349 NCC1OC(OC2C(N)CC(N)C(O)C2O[C@@H]3OC[C@H](COCC4OCC(O)C(O)C4N)[C@@H]3O)C(N)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L14 compound treatment 131480.0 -2220.0 -0.07 116440.0 -18500.0 -0.48 -0.3895 -0.8001 3055065 HSCI1_000350 Nc1ncn([C@@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L15 mock treatment 135480.0 1780.0 0.06 128760.0 -6230.0 -0.16 -0.0755 -0.4417 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L16 mock treatment 124160.0 -9540.0 -0.3 128400.0 -6590.0 -0.17 -0.3301 -0.9662 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L17 compound treatment 126480.0 -7220.0 -0.22 101000.0 -34000.0 -0.88 -0.7827 -0.8592 372 HSCI1_000351 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L18 compound treatment 130040.0 -3660.0 -0.11 118040.0 -16900.0 -0.44 -0.3916 -0.8612 1367 HSCI1_000352 Cc1cc(O)ccc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L19 compound treatment 10600.0 -123000.0 -3.81 8960.0 -126000.0 -3.27 -5.0126 -0.9971 3055069 HSCI1_000353 CC/C(=C(\c1ccc(O)cc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L20 compound treatment 120040.0 -13700.0 -0.42 135560.0 573.0 0.01 -0.2888 -0.6818 2237 HSCI1_000354 FS(=O)(=O)Cc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L21 mock treatment 129080.0 -4620.0 -0.14 118680.0 -16300.0 -0.42 -0.4009 -0.8963 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L22 mock treatment 131320.0 -2380.0 -0.07 131040.0 -3950.0 -0.1 -0.1247 -0.987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L23 mock treatment 137360.0 3660.0 0.11 131800.0 -3190.0 -0.08 0.0216 0.1536 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 L24 mock treatment 136880.0 3180.0 0.1 142040.0 7050.0 0.18 0.1992 0.9575 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M01 mock treatment 116920.0 -16800.0 -0.52 123440.0 -11500.0 -0.3 -0.5799 -0.9658 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M02 compound treatment 134280.0 577.0 0.02 151720.0 16700.0 0.43 0.3201 0.7355 1900 HSCI1_000355 COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M03 compound treatment 20480.0 -113000.0 -3.51 11800.0 -123000.0 -3.2 -4.7439 -0.999 3055072 HSCI1_000356 Cn1cc(/C=C/2\C(=O)Nc3ccc(cc23)S(=O)(=O)N)c4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M04 compound treatment 26080.0 -108000.0 -3.33 17960.0 -117000.0 -3.04 -4.508 -0.9989 292 HSCI1_000357 O=C1NCc2c1c3c4ccccc4[nH]c3c5[nH]c6ccccc6c25 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M05 compound treatment 95480.0 -38200.0 -1.18 67160.0 -67800.0 -1.76 -2.0836 -0.9813 907290 HSCI1_000358 CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](O)[C@@]3(C)O[C@](C)(CC(=O)[C@@]32O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M06 compound treatment 142880.0 9180.0 0.28 100400.0 -34600.0 -0.9 -0.4344 -0.4609 3055076 HSCI1_000359 NS(=O)(=O)c1ccc(N/C=C/2\C(=O)Nc3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M07 compound treatment 117280.0 -16400.0 -0.51 85800.0 -49200.0 -1.28 -1.2635 -0.9185 3055122 HSCI1_000360 OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c5cccc1c52 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M08 compound treatment 37000.0 -96700.0 -3.0 30400.0 -105000.0 -2.72 -4.0402 -0.9988 3176387 HSCI1_000361 Nc1cccc(c1)c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M09 mock treatment 123080.0 -10600.0 -0.33 117160.0 -17800.0 -0.46 -0.5603 -0.986 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M10 mock treatment 129040.0 -4660.0 -0.14 131440.0 -3550.0 -0.09 -0.1673 -0.9764 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M11 mock treatment 122200.0 -11500.0 -0.36 133200.0 -1790.0 -0.05 -0.2849 -0.7925 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M12 mock treatment 117480.0 -16200.0 -0.5 119200.0 -15800.0 -0.41 -0.6455 -0.9949 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M13 mock treatment 120560.0 -13100.0 -0.41 118160.0 -16800.0 -0.44 -0.5971 -0.9994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M14 mock treatment 145360.0 11700.0 0.36 137760.0 2770.0 0.07 0.3063 0.8318 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M15 compound treatment 157040.0 23300.0 0.72 127680.0 -7310.0 -0.19 0.377 0.5043 2796 HSCI1_000362 CCCCCCCC/C=C\CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M16 compound treatment 10960.0 -123000.0 -3.8 9360.0 -126000.0 -3.26 -4.9973 -0.9971 3176388 HSCI1_000363 COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@H]1[C@@H]2c3cc4OCOc4cc3CCN5CCC[C@]25C=C1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M17 compound treatment 36520.0 -97200.0 -3.01 20720.0 -114000.0 -2.97 -4.2286 -1.0 1000076 HSCI1_000364 CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M18 compound treatment 123960.0 -9740.0 -0.3 104840.0 -30100.0 -0.78 -0.7673 -0.9141 2058 HSCI1_000365 OC(=O)C1C(C2CCC1O2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M19 compound treatment 140320.0 6620.0 0.21 112480.0 -22500.0 -0.58 -0.2685 -0.4334 1000072 HSCI1_000366 CC(C)OP(=O)(F)OC(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M20 compound treatment 8800.0 -125000.0 -3.87 7080.0 -128000.0 -3.32 -5.0865 -0.9971 3176389 HSCI1_000367 CC(=O)O[C@@H]1CC2[C@@]3(C)CCCC(C)(C)C3CC[C@@]2(C)C4CC=C(C=O)[C@H](C=O)[C@@]14C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M21 compound treatment 130920.0 -2780.0 -0.09 118160.0 -16800.0 -0.44 -0.3701 -0.8306 3176390 HSCI1_000368 CCCC(=O)OC1C(OC2COP(O)(O)OC12)n3cnc4c(=O)[nH]c(NOC(=C)CC)nc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M22 compound treatment 90280.0 -43400.0 -1.35 72960.0 -62000.0 -1.61 -2.091 -0.996 3055129 HSCI1_000369 CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@@]21C)c5ccc(cc5)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M23 mock treatment 137440.0 3740.0 0.12 131600.0 -3390.0 -0.09 0.0196 0.135 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 M24 mock treatment 119800.0 -13900.0 -0.43 127400.0 -7590.0 -0.2 -0.444 -0.9372 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N01 mock treatment 133720.0 16.7 0.0 112840.0 -22100.0 -0.58 -0.4065 -0.7065 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N02 compound treatment 98920.0 -34800.0 -1.08 91240.0 -43700.0 -1.14 -1.5658 -0.9996 600 HSCI1_000370 COC(=O)/C=C/c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N03 compound treatment 6440.0 -127000.0 -3.94 4760.0 -130000.0 -3.38 -5.1809 -0.9971 630 HSCI1_000371 COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C/C=C/c3ccc(Cl)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N04 compound treatment 5880.0 -128000.0 -3.96 4160.0 -131000.0 -3.4 -5.2042 -0.9971 2283 HSCI1_000372 CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N05 compound treatment 89800.0 -43900.0 -1.36 67160.0 -67800.0 -1.76 -2.2081 -0.9918 629 HSCI1_000373 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2CN(C)C/C=C/c3ccc(Cl)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N06 compound treatment 136240.0 2540.0 0.08 113120.0 -21900.0 -0.57 -0.3462 -0.6035 1884 HSCI1_000374 Cc1ccnc(N)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N07 compound treatment 9720.0 -124000.0 -3.84 7200.0 -128000.0 -3.32 -5.0642 -0.9974 1918023 HSCI1_000375 CC[n+]1c(/C=C/N(C)c2ccccc2)n(c3ccccc3)c4ccc(cc14)c5nc6ccccc6s5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N08 compound treatment 142760.0 9060.0 0.28 116760.0 -18200.0 -0.47 -0.1365 -0.2479 2344 HSCI1_000376 FC(F)(F)C(=O)CC(=O)c1cccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N09 mock treatment 127160.0 -6540.0 -0.2 123920.0 -11100.0 -0.29 -0.3467 -0.9854 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N10 mock treatment 130040.0 -3660.0 -0.11 127320.0 -7670.0 -0.2 -0.2211 -0.9644 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N11 mock treatment 119680.0 -14000.0 -0.43 130200.0 -4790.0 -0.12 -0.3952 -0.8744 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N12 mock treatment 136200.0 2500.0 0.08 125320.0 -9670.0 -0.25 -0.1229 -0.4677 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N13 mock treatment 136840.0 3140.0 0.1 132200.0 -2790.0 -0.07 0.0175 0.1445 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N14 mock treatment 131720.0 -1980.0 -0.06 128360.0 -6630.0 -0.17 -0.1652 -0.9036 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N15 compound treatment 12000.0 -122000.0 -3.77 10080.0 -125000.0 -3.25 -4.9613 -0.9972 1000048 HSCI1_000377 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N16 compound treatment 152760.0 19100.0 0.59 126440.0 -8550.0 -0.22 0.2605 0.4129 2187 HSCI1_000378 O=C(NC1CCCCC1)NC2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N17 compound treatment 132680.0 -1020.0 -0.03 109680.0 -25300.0 -0.66 -0.4874 -0.7403 2083 HSCI1_000379 CC(CCC(=O)NCC(=O)O)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N18 compound treatment 130120.0 -3580.0 -0.11 115680.0 -19300.0 -0.5 -0.4332 -0.8432 1934 HSCI1_000380 NNC(=N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N19 compound treatment 119200.0 -14500.0 -0.45 81920.0 -53100.0 -1.38 -1.2927 -0.8914 30 HSCI1_000381 COC(=O)C1=C(C)NC(=C(C1c2ccccc2C(F)(F)F)[N+](=O)[O-])C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N20 compound treatment 12240.0 -121000.0 -3.76 7440.0 -128000.0 -3.31 -5.0046 -0.998 420 HSCI1_000382 CCN1C(=O)C=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N21 compound treatment 122840.0 -10900.0 -0.34 102240.0 -32700.0 -0.85 -0.8397 -0.9176 3054850 HSCI1_000383 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N22 compound treatment 104040.0 -29700.0 -0.92 85800.0 -49200.0 -1.28 -1.5536 -0.9869 2003 HSCI1_000384 CNC1CCc2cc(OC)c(OC)c(OC)c2-c3ccc(OC)c(=O)cc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N23 mock treatment 128520.0 -5180.0 -0.16 115480.0 -19500.0 -0.51 -0.472 -0.8877 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 N24 mock treatment 125800.0 -7900.0 -0.24 123440.0 -11500.0 -0.3 -0.3853 -0.9949 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O01 mock treatment 106440.0 -27300.0 -0.84 115840.0 -19100.0 -0.5 -0.9491 -0.9681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O02 mock treatment 128680.0 -5020.0 -0.16 162240.0 27300.0 0.71 0.3907 0.5388 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O03 compound treatment 7200.0 -127000.0 -3.92 5600.0 -129000.0 -3.36 -5.1488 -0.9971 3054852 HSCI1_000385 O=C/1Nc2ccc(cc2\C1=C\c3ccc[nH]3)c4cccnc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O04 compound treatment 66640.0 -67100.0 -2.08 42800.0 -92200.0 -2.4 -3.163 -0.9975 3176393 HSCI1_000386 Cn1nc(N)c2cn(C3OC(CO)C(O)C3O)c4ncnc1c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O05 compound treatment 13280.0 -120000.0 -3.73 4800.0 -130000.0 -3.38 -5.0303 -0.9988 3176394 HSCI1_000387 C1CCC(CC1)Nc2nc(Nc3ccc(cc3)N4CCOCC4)nc5[nH]cnc25 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O06 compound treatment 90160.0 -43500.0 -1.35 45320.0 -89700.0 -2.33 -2.6014 -0.9663 575 HSCI1_000388 O=C1NC(=O)C(=C1c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O07 compound treatment 63480.0 -70200.0 -2.18 49640.0 -85300.0 -2.22 -3.1066 -1.0 3176395 HSCI1_000389 CCCCN1C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@@H](N2C1=O)c5ccc(OC)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O08 compound treatment 66880.0 -66800.0 -2.07 28240.0 -107000.0 -2.77 -3.4253 -0.9896 2116778 HSCI1_000390 CCOC(=O)c1cnc2oc3ccc(O)cc3c2c1c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O09 compound treatment 23440.0 -110000.0 -3.42 19360.0 -116000.0 -3.0 -4.5402 -0.9979 3176396 HSCI1_000391 CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c3ncn(C(C)C)c3n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O10 compound treatment 90920.0 -42800.0 -1.33 67720.0 -67300.0 -1.75 -2.1732 -0.9907 676 HSCI1_000392 COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O11 mock treatment 126280.0 -7420.0 -0.23 123760.0 -11200.0 -0.29 -0.3689 -0.9931 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O12 mock treatment 143480.0 9780.0 0.3 115200.0 -19800.0 -0.51 -0.1493 -0.2503 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O13 mock treatment 118400.0 -15300.0 -0.47 128280.0 -6710.0 -0.17 -0.4585 -0.9076 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O14 mock treatment 113160.0 -20500.0 -0.64 126600.0 -8390.0 -0.22 -0.6042 -0.898 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O15 compound treatment 130400.0 -3300.0 -0.1 125640.0 -9350.0 -0.24 -0.2441 -0.9262 1398 HSCI1_000393 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O16 compound treatment 10800.0 -123000.0 -3.81 8840.0 -126000.0 -3.28 -5.0104 -0.9972 2060355 HSCI1_000394 CC1=C(C=C)/C(=C/c2[nH]c(Cc3[nH]c(\C=C\4/NC(=O)C(=C4C)C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)/NC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O17 compound treatment 129880.0 -3820.0 -0.12 118600.0 -16400.0 -0.43 -0.3848 -0.8708 1929 HSCI1_000395 Nc1cccc2c(=O)[nH]ccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O18 compound treatment 132080.0 -1620.0 -0.05 94240.0 -40700.0 -1.06 -0.7842 -0.7399 2286 HSCI1_000396 CCSC(=N)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O19 compound treatment 121560.0 -12100.0 -0.38 131560.0 -3430.0 -0.09 -0.329 -0.8509 23 HSCI1_000397 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O20 compound treatment 10240.0 -123000.0 -3.83 5920.0 -129000.0 -3.35 -5.0763 -0.9978 3054913 HSCI1_000398 Cc1ccc(cc1)S(=O)(=O)N[C@H](Cc2ccccc2)C(=O)CCl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O21 compound treatment 8320.0 -125000.0 -3.88 6240.0 -129000.0 -3.35 -5.1125 -0.9972 3176397 HSCI1_000399 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C/3\C[C@@H](O)C[C@H](O)C3=C)/CCC[C@@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O22 compound treatment 126760.0 -6940.0 -0.22 112640.0 -22300.0 -0.58 -0.5627 -0.9087 988 HSCI1_000400 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O23 mock treatment 140920.0 7220.0 0.22 127760.0 -7230.0 -0.19 0.0253 0.0868 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 O24 mock treatment 140240.0 6540.0 0.2 131840.0 -3150.0 -0.08 0.0854 0.391 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P01 mock treatment 73480.0 -60200.0 -1.87 88440.0 -46500.0 -1.21 -2.1746 -0.978 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P02 mock treatment 116880.0 -16800.0 -0.52 115920.0 -19100.0 -0.5 -0.7189 -0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P03 mock treatment 126800.0 -6900.0 -0.21 103800.0 -31200.0 -0.81 -0.7242 -0.8642 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P04 mock treatment 132280.0 -1420.0 -0.04 96480.0 -38500.0 -1.0 -0.7387 -0.7376 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P05 mock treatment 133600.0 -103.0 0.0 99680.0 -35300.0 -0.92 -0.6509 -0.7096 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P06 mock treatment 116440.0 -17300.0 -0.53 105040.0 -29900.0 -0.78 -0.9284 -0.9833 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P07 mock treatment 95280.0 -38400.0 -1.19 103600.0 -31400.0 -0.82 -1.4185 -0.983 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P08 mock treatment 109400.0 -24300.0 -0.75 98800.0 -36200.0 -0.94 -1.1973 -0.9939 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P09 mock treatment 122560.0 -11100.0 -0.35 95200.0 -39800.0 -1.03 -0.9751 -0.8947 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P10 mock treatment 125280.0 -8420.0 -0.26 94400.0 -40600.0 -1.05 -0.9302 -0.8563 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P11 mock treatment 120960.0 -12700.0 -0.39 115240.0 -19700.0 -0.51 -0.642 -0.9916 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P12 mock treatment 115400.0 -18300.0 -0.57 119040.0 -15900.0 -0.41 -0.694 -0.9881 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P13 mock treatment 124240.0 -9460.0 -0.29 116840.0 -18100.0 -0.47 -0.5407 -0.9739 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P14 mock treatment 109760.0 -23900.0 -0.74 123640.0 -11300.0 -0.29 -0.7331 -0.9183 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P15 mock treatment 124160.0 -9540.0 -0.3 109520.0 -25500.0 -0.66 -0.677 -0.9341 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P16 mock treatment 119200.0 -14500.0 -0.45 98800.0 -36200.0 -0.94 -0.9826 -0.9429 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P17 mock treatment 113040.0 -20700.0 -0.64 94600.0 -40400.0 -1.05 -1.1947 -0.9719 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P18 mock treatment 118760.0 -14900.0 -0.46 104440.0 -30500.0 -0.79 -0.8886 -0.9671 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P19 mock treatment 118640.0 -15100.0 -0.47 104040.0 -30900.0 -0.8 -0.8986 -0.9665 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P20 mock treatment 116840.0 -16900.0 -0.52 102720.0 -32300.0 -0.84 -0.9623 -0.9741 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P21 mock treatment 125680.0 -8020.0 -0.25 104000.0 -31000.0 -0.81 -0.7451 -0.8842 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P22 mock treatment 127480.0 -6220.0 -0.19 114240.0 -20700.0 -0.54 -0.5175 -0.904 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P23 mock treatment 104280.0 -29400.0 -0.91 105640.0 -29300.0 -0.76 -1.1838 -0.9961 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2105 P24 mock treatment 72400.0 -61300.0 -1.9 115520.0 -19500.0 -0.51 -1.7008 -0.8653 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A01 compound treatment 76720.0 -48500.0 -1.5 18880.0 -16300.0 -0.42 -1.3627 -0.8725 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A02 compound treatment 106720.0 -18500.0 -0.57 21360.0 -13800.0 -0.36 -0.6599 -0.9746 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A03 compound treatment 138640.0 13400.0 0.42 28880.0 -6310.0 -0.16 0.1776 0.3979 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A04 compound treatment 130360.0 5120.0 0.16 24760.0 -10400.0 -0.27 -0.0795 -0.253 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A05 compound treatment 96560.0 -28700.0 -0.89 25160.0 -10000.0 -0.26 -0.8127 -0.8776 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A06 compound treatment 101480.0 -23800.0 -0.74 23600.0 -11600.0 -0.3 -0.7335 -0.9222 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A07 compound treatment 74880.0 -50400.0 -1.56 24400.0 -10800.0 -0.28 -1.3016 -0.821 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A08 compound treatment 93440.0 -31800.0 -0.99 18640.0 -16600.0 -0.43 -1.0008 -0.9309 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A09 compound treatment 59080.0 -66200.0 -2.05 20440.0 -14800.0 -0.38 -1.7205 -0.825 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A10 compound treatment 79360.0 -45900.0 -1.42 23360.0 -11800.0 -0.31 -1.2226 -0.8406 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A11 compound treatment 66040.0 -59200.0 -1.83 15600.0 -19600.0 -0.51 -1.657 -0.8705 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A12 compound treatment 125120.0 -119.0 0.0 23640.0 -11600.0 -0.3 -0.2149 -0.7157 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A13 mock treatment 151960.0 26700.0 0.83 26720.0 -8470.0 -0.22 0.4298 0.5017 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A14 mock treatment 142120.0 16900.0 0.52 30800.0 -4390.0 -0.11 0.2891 0.5401 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A15 compound treatment 125880.0 641.0 0.02 32200.0 -2990.0 -0.08 -0.0409 -0.5101 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A16 compound treatment 143200.0 18000.0 0.56 30520.0 -4670.0 -0.12 0.3077 0.5401 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A17 compound treatment 164800.0 39600.0 1.23 36200.0 1010.0 0.03 0.8853 0.722 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A18 compound treatment 130480.0 5240.0 0.16 27920.0 -7270.0 -0.19 -0.0188 -0.0754 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A19 compound treatment 91480.0 -33800.0 -1.05 28160.0 -7030.0 -0.18 -0.8688 -0.8182 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A20 compound treatment 174080.0 48800.0 1.51 36240.0 1050.0 0.03 1.0893 0.7197 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A21 compound treatment 110360.0 -14900.0 -0.46 29400.0 -5790.0 -0.15 -0.4324 -0.8916 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A22 compound treatment 164440.0 39200.0 1.21 31240.0 -3950.0 -0.1 0.7862 0.645 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A23 compound treatment 95880.0 -29400.0 -0.91 23200.0 -12000.0 -0.31 -0.8636 -0.8981 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 A24 compound treatment 99440.0 -25800.0 -0.8 24560.0 -10600.0 -0.28 -0.7606 -0.8993 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B01 compound treatment 104400.0 -20800.0 -0.65 22680.0 -12500.0 -0.33 -0.6865 -0.9496 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B02 compound treatment 192280.0 67000.0 2.08 44600.0 9410.0 0.24 1.6417 0.7849 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B03 compound treatment 197760.0 72500.0 2.25 42640.0 7450.0 0.19 1.7257 0.7652 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B04 compound treatment 135040.0 9800.0 0.3 29440.0 -5750.0 -0.15 0.109 0.3222 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B05 compound treatment 215720.0 90500.0 2.8 48560.0 13400.0 0.35 2.228 0.7887 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B06 compound treatment 158440.0 33200.0 1.03 43840.0 8650.0 0.22 0.8863 0.8417 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B07 compound treatment 135880.0 10600.0 0.33 41560.0 6370.0 0.17 0.3501 0.9491 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B08 compound treatment 142000.0 16800.0 0.52 48000.0 12800.0 0.33 0.6025 0.9769 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B09 compound treatment 173360.0 48100.0 1.49 42440.0 7250.0 0.19 1.1874 0.7901 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B10 compound treatment 80280.0 -45000.0 -1.39 38040.0 2850.0 0.07 -0.9327 -0.6686 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B11 compound treatment 182200.0 57000.0 1.76 44640.0 9450.0 0.25 1.4215 0.7978 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B12 compound treatment 120160.0 -5080.0 -0.16 23800.0 -11400.0 -0.3 -0.3206 -0.9563 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B13 mock treatment 188080.0 62800.0 1.95 40800.0 5610.0 0.15 1.4798 0.7579 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B14 mock treatment 207440.0 82200.0 2.55 44080.0 8890.0 0.23 1.9643 0.7681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B15 compound treatment 185800.0 60600.0 1.88 44120.0 8930.0 0.23 1.4909 0.7885 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B16 compound treatment 83760.0 -41500.0 -1.29 23360.0 -11800.0 -0.31 -1.1262 -0.8522 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B17 compound treatment 159000.0 33800.0 1.05 43680.0 8490.0 0.22 0.8956 0.8378 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B18 compound treatment 103640.0 -21600.0 -0.67 45520.0 10300.0 0.27 -0.2835 -0.3932 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B19 compound treatment 191000.0 65800.0 2.04 43240.0 8050.0 0.21 1.5886 0.7756 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B20 compound treatment 202000.0 76800.0 2.38 49600.0 14400.0 0.37 1.9465 0.8084 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B21 compound treatment 205600.0 80400.0 2.49 44080.0 8890.0 0.23 1.9239 0.7694 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B22 compound treatment 144200.0 19000.0 0.59 34680.0 -513.0 -0.01 0.406 0.6909 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B23 compound treatment 168440.0 43200.0 1.34 40480.0 5290.0 0.14 1.0436 0.7756 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 B24 compound treatment 92920.0 -32300.0 -1.0 17160.0 -18000.0 -0.47 -1.0394 -0.9401 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C01 compound treatment 83680.0 -41600.0 -1.29 27040.0 -8150.0 -0.21 -1.0603 -0.8125 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C02 compound treatment 156960.0 31700.0 0.98 41040.0 5850.0 0.15 0.8024 0.8068 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C03 compound treatment 163160.0 37900.0 1.17 41960.0 6770.0 0.18 0.9552 0.804 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C04 compound treatment 155160.0 29900.0 0.93 37360.0 2170.0 0.06 0.6954 0.7487 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C05 compound treatment 175200.0 50000.0 1.55 45240.0 10000.0 0.26 1.2792 0.8148 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C06 compound treatment 187960.0 62700.0 1.94 41320.0 6130.0 0.16 1.4867 0.7625 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C07 compound treatment 95920.0 -29300.0 -0.91 31960.0 -3230.0 -0.08 -0.7018 -0.7692 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C08 compound treatment 150640.0 25400.0 0.79 32440.0 -2750.0 -0.07 0.5059 0.6402 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C09 compound treatment 113680.0 -11600.0 -0.36 38600.0 3410.0 0.09 -0.1907 -0.5168 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C10 compound treatment 93880.0 -31400.0 -0.97 28000.0 -7190.0 -0.19 -0.8192 -0.8279 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C11 mock treatment 188960.0 63700.0 1.97 42400.0 7210.0 0.19 1.5285 0.7707 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C12 mock treatment 185280.0 60000.0 1.86 38680.0 3490.0 0.09 1.3795 0.7407 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C13 compound treatment 218200.0 93000.0 2.88 42040.0 6850.0 0.18 2.1625 0.7494 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C14 compound treatment 99760.0 -25500.0 -0.79 33320.0 -1870.0 -0.05 -0.5926 -0.7493 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C15 mock treatment 209240.0 84000.0 2.6 42240.0 7050.0 0.18 1.9699 0.755 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C16 mock treatment 163960.0 38700.0 1.2 47080.0 11900.0 0.31 1.0668 0.8611 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C17 compound treatment 184520.0 59300.0 1.84 45160.0 9970.0 0.26 1.4819 0.7989 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C18 compound treatment 80600.0 -44600.0 -1.38 30200.0 -4990.0 -0.13 -1.0697 -0.77 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C19 compound treatment 158880.0 33600.0 1.04 40480.0 5290.0 0.14 0.8342 0.7934 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C20 compound treatment 195600.0 70400.0 2.18 39160.0 3970.0 0.1 1.6145 0.7397 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C21 compound treatment 183240.0 58000.0 1.8 45760.0 10600.0 0.27 1.4649 0.8058 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C22 compound treatment 157880.0 32600.0 1.01 46480.0 11300.0 0.29 0.9225 0.8761 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C23 compound treatment 151360.0 26100.0 0.81 47760.0 12600.0 0.33 0.8032 0.9203 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 C24 compound treatment 145040.0 19800.0 0.61 32160.0 -3030.0 -0.08 0.3781 0.6113 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D01 compound treatment 132760.0 7520.0 0.23 44520.0 9330.0 0.24 0.3361 0.9998 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D02 compound treatment 107560.0 -17700.0 -0.55 11000.0 -24200.0 -0.63 -0.8318 -0.9976 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D03 compound treatment 156800.0 31600.0 0.98 54400.0 19200.0 0.5 1.0444 0.9513 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D04 compound treatment 144280.0 19000.0 0.59 53000.0 17800.0 0.46 0.7443 0.9928 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D05 compound treatment 184040.0 58800.0 1.82 77920.0 42700.0 1.11 2.0733 0.9718 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D06 compound treatment 98720.0 -26500.0 -0.82 10840.0 -24400.0 -0.63 -1.0284 -0.9917 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D07 compound treatment 162520.0 37300.0 1.16 62000.0 26800.0 0.7 1.3093 0.9707 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D08 compound treatment 169280.0 44000.0 1.36 57400.0 22200.0 0.58 1.3729 0.9267 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D09 compound treatment 148960.0 23700.0 0.73 52280.0 17100.0 0.44 0.8336 0.9709 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D10 compound treatment 181760.0 56500.0 1.75 59760.0 24600.0 0.64 1.6897 0.9065 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D11 mock treatment 164920.0 39700.0 1.23 53800.0 18600.0 0.48 1.2112 0.9168 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D12 mock treatment 157640.0 32400.0 1.0 44840.0 9650.0 0.25 0.8871 0.8573 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D13 compound treatment 142560.0 17300.0 0.54 48760.0 13600.0 0.35 0.6288 0.9792 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D14 compound treatment 174000.0 48800.0 1.51 59600.0 24400.0 0.63 1.5167 0.9257 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D15 mock treatment 169840.0 44600.0 1.38 56200.0 21000.0 0.55 1.3631 0.9174 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D16 mock treatment 175080.0 49800.0 1.54 56920.0 21700.0 0.56 1.4912 0.9069 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D17 compound treatment 171200.0 46000.0 1.42 54480.0 19300.0 0.5 1.3613 0.9017 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D18 compound treatment 161200.0 36000.0 1.11 57200.0 22000.0 0.57 1.1922 0.9519 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D19 compound treatment 140800.0 15600.0 0.48 49720.0 14500.0 0.38 0.6078 0.9927 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D20 compound treatment 108120.0 -17100.0 -0.53 37440.0 2250.0 0.06 -0.3338 -0.6255 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D21 compound treatment 147800.0 22600.0 0.7 63000.0 27800.0 0.72 1.0052 0.9999 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D22 compound treatment 96800.0 -28400.0 -0.88 26560.0 -8630.0 -0.22 -0.7817 -0.8597 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D23 compound treatment 156320.0 31100.0 0.96 43200.0 8010.0 0.21 0.8281 0.8405 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 D24 compound treatment 72520.0 -52700.0 -1.63 17320.0 -17900.0 -0.46 -1.4834 -0.8735 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E01 mock treatment 164800.0 39600.0 1.23 33880.0 -1310.0 -0.03 0.8426 0.6872 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E02 mock treatment 135640.0 10400.0 0.32 40760.0 5570.0 0.14 0.3302 0.9347 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E03 compound treatment 132960.0 7720.0 0.24 29440.0 -5750.0 -0.15 0.0635 0.225 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E04 compound treatment 163240.0 38000.0 1.18 36960.0 1770.0 0.05 0.865 0.7341 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E05 compound treatment 122280.0 -2960.0 -0.09 38000.0 2810.0 0.07 -0.0133 -0.1131 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E06 compound treatment 149600.0 24400.0 0.75 37520.0 2330.0 0.06 0.5765 0.7613 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E07 compound treatment 141440.0 16200.0 0.5 41640.0 6450.0 0.17 0.4734 0.8946 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E08 compound treatment 84600.0 -40600.0 -1.26 28680.0 -6510.0 -0.17 -1.01 -0.795 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E09 mock treatment 122560.0 -2680.0 -0.08 39760.0 4570.0 0.12 0.0252 0.1741 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E10 mock treatment 158720.0 33500.0 1.04 38880.0 3690.0 0.1 0.8013 0.7691 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E11 compound treatment 145600.0 20400.0 0.63 37600.0 2410.0 0.06 0.4903 0.7734 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E12 compound treatment 149080.0 23800.0 0.74 32600.0 -2590.0 -0.07 0.4747 0.64 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E13 compound treatment 129320.0 4080.0 0.13 40920.0 5730.0 0.15 0.1946 0.9967 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E14 compound treatment 152120.0 26900.0 0.83 29520.0 -5670.0 -0.15 0.4847 0.5731 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E15 compound treatment 146240.0 21000.0 0.65 33440.0 -1750.0 -0.05 0.4279 0.656 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E16 compound treatment 24840.0 -100000.0 -3.11 6080.0 -29100.0 -0.76 -2.7346 -0.8542 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E17 mock treatment 135880.0 10600.0 0.33 45240.0 10000.0 0.26 0.4177 0.9933 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E18 mock treatment 147480.0 22200.0 0.69 42160.0 6970.0 0.18 0.6153 0.8636 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E19 compound treatment 128040.0 2800.0 0.09 44000.0 8810.0 0.23 0.2232 0.9119 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E20 compound treatment 171640.0 46400.0 1.44 36280.0 1090.0 0.03 1.0366 0.7209 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E21 compound treatment 112640.0 -12600.0 -0.39 42040.0 6850.0 0.18 -0.1502 -0.3502 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E22 compound treatment 146480.0 21200.0 0.66 39680.0 4490.0 0.12 0.5478 0.8196 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E23 compound treatment 130800.0 5560.0 0.17 30960.0 -4230.0 -0.11 0.0441 0.2156 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 E24 compound treatment 100120.0 -25100.0 -0.78 30480.0 -4710.0 -0.12 -0.6369 -0.8084 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F01 mock treatment 170000.0 44800.0 1.39 36760.0 1570.0 0.04 1.0095 0.7276 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F02 mock treatment 129080.0 3840.0 0.12 48000.0 12800.0 0.33 0.3195 0.9039 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F03 compound treatment 129440.0 4200.0 0.13 49640.0 14400.0 0.38 0.3575 0.8997 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F04 compound treatment 91320.0 -33900.0 -1.05 15080.0 -20100.0 -0.52 -1.1127 -0.948 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F05 compound treatment 140680.0 15400.0 0.48 44440.0 9250.0 0.24 0.5082 0.9492 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F06 compound treatment 159040.0 33800.0 1.05 42240.0 7050.0 0.18 0.87 0.8183 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F07 compound treatment 132040.0 6800.0 0.21 33320.0 -1870.0 -0.05 0.1146 0.5299 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F08 compound treatment 123840.0 -1400.0 -0.04 15640.0 -19600.0 -0.51 -0.3899 -0.7647 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F09 mock treatment 129840.0 4600.0 0.14 40480.0 5290.0 0.14 0.1979 0.9998 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F10 mock treatment 133080.0 7840.0 0.24 40360.0 5170.0 0.13 0.2667 0.9609 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F11 compound treatment 126800.0 1560.0 0.05 44280.0 9090.0 0.24 0.2012 0.8346 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F12 compound treatment 143760.0 18500.0 0.57 39560.0 4370.0 0.11 0.486 0.8308 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F13 compound treatment 135240.0 10000.0 0.31 38720.0 3530.0 0.09 0.2839 0.8786 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F14 compound treatment 115280.0 -9960.0 -0.31 29720.0 -5470.0 -0.14 -0.3187 -0.9381 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F15 compound treatment 143800.0 18600.0 0.58 43040.0 7850.0 0.2 0.5508 0.9027 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F16 compound treatment 96200.0 -29000.0 -0.9 20240.0 -15000.0 -0.39 -0.9109 -0.9295 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F17 mock treatment 136080.0 10800.0 0.34 41040.0 5850.0 0.15 0.3449 0.9357 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F18 mock treatment 127920.0 2680.0 0.08 43320.0 8130.0 0.21 0.2081 0.9169 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F19 compound treatment 115160.0 -10100.0 -0.31 35360.0 167.0 0.0 -0.2178 -0.6972 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F20 compound treatment 105960.0 -19300.0 -0.6 14360.0 -20800.0 -0.54 -0.8051 -0.9988 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F21 compound treatment 157720.0 32500.0 1.01 45920.0 10700.0 0.28 0.9087 0.8702 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F22 compound treatment 100120.0 -25100.0 -0.78 33480.0 -1710.0 -0.04 -0.5818 -0.7463 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F23 compound treatment 131960.0 6720.0 0.21 38720.0 3530.0 0.09 0.2121 0.932 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 F24 compound treatment 117560.0 -7680.0 -0.24 28200.0 -6990.0 -0.18 -0.2967 -0.9911 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G01 compound treatment 166080.0 40800.0 1.27 38280.0 3090.0 0.08 0.9515 0.7504 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G02 compound treatment 41800.0 -83400.0 -2.59 8080.0 -27100.0 -0.7 -2.3262 -0.8681 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G03 mock treatment 139160.0 13900.0 0.43 42640.0 7450.0 0.19 0.4418 0.9346 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G04 mock treatment 125680.0 441.0 0.01 37440.0 2250.0 0.06 0.0509 0.8496 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G05 compound treatment 145480.0 20200.0 0.63 41280.0 6090.0 0.16 0.5553 0.8586 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G06 compound treatment 122040.0 -3200.0 -0.1 25520.0 -9670.0 -0.25 -0.2478 -0.9172 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G07 compound treatment 101760.0 -23500.0 -0.73 29680.0 -5510.0 -0.14 -0.6157 -0.8304 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G08 compound treatment 125160.0 -79.0 0.0 22720.0 -12500.0 -0.32 -0.2309 -0.7124 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G09 compound treatment 147240.0 22000.0 0.68 41160.0 5970.0 0.16 0.5917 0.8463 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G10 compound treatment 118480.0 -6760.0 -0.21 43960.0 8770.0 0.23 0.013 0.042 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G11 compound treatment 139240.0 14000.0 0.43 47200.0 12000.0 0.31 0.5274 0.9869 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G12 compound treatment 134360.0 9120.0 0.28 32360.0 -2830.0 -0.07 0.1478 0.5061 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G13 compound treatment 126440.0 1200.0 0.04 40120.0 4930.0 0.13 0.1168 0.8764 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G14 compound treatment 125320.0 81.0 0.0 35040.0 -153.0 0.0 -0.001 -0.2199 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G15 compound treatment 152760.0 27500.0 0.85 39880.0 4690.0 0.12 0.6891 0.8 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G16 compound treatment 94320.0 -30900.0 -0.96 26960.0 -8230.0 -0.21 -0.8287 -0.8442 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G17 compound treatment 127520.0 2280.0 0.07 31280.0 -3910.0 -0.1 -0.0219 -0.177 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G18 compound treatment 120720.0 -4520.0 -0.14 45120.0 9930.0 0.26 0.0834 0.2841 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G19 mock treatment 124880.0 -359.0 -0.01 42920.0 7730.0 0.2 0.1341 0.6669 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G20 mock treatment 121440.0 -3800.0 -0.12 43600.0 8410.0 0.22 0.0712 0.2871 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G21 compound treatment 131560.0 6320.0 0.2 49320.0 14100.0 0.37 0.398 0.9567 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G22 compound treatment 131800.0 6560.0 0.2 45200.0 10000.0 0.26 0.3276 0.9926 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G23 compound treatment 132240.0 7000.0 0.22 39480.0 4290.0 0.11 0.2322 0.952 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 G24 compound treatment 111120.0 -14100.0 -0.44 25680.0 -9510.0 -0.25 -0.4841 -0.9635 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H01 compound treatment 159000.0 33800.0 1.05 33280.0 -1910.0 -0.05 0.7045 0.6728 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H02 compound treatment 134720.0 9480.0 0.29 41240.0 6050.0 0.16 0.3188 0.957 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H03 mock treatment 120720.0 -4520.0 -0.14 47520.0 12300.0 0.32 0.1275 0.3647 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H04 mock treatment 131000.0 5760.0 0.18 43040.0 7850.0 0.2 0.2704 0.9978 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H05 compound treatment 161320.0 36100.0 1.12 36680.0 1490.0 0.04 0.8178 0.7311 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H06 compound treatment 125160.0 -79.0 0.0 18920.0 -16300.0 -0.42 -0.3007 -0.7112 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H07 compound treatment 160400.0 35200.0 1.09 46440.0 11200.0 0.29 0.977 0.8662 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H08 compound treatment 141760.0 16500.0 0.51 43400.0 8210.0 0.21 0.5128 0.9247 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H09 compound treatment 115240.0 -10000.0 -0.31 39120.0 3930.0 0.1 -0.1469 -0.4504 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H10 compound treatment 138760.0 13500.0 0.42 42200.0 7010.0 0.18 0.425 0.9304 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H11 compound treatment 121600.0 -3640.0 -0.11 35440.0 247.0 0.01 -0.0752 -0.6657 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H12 compound treatment 118400.0 -6840.0 -0.21 22160.0 -13000.0 -0.34 -0.3893 -0.9745 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H13 compound treatment 115720.0 -9520.0 -0.29 35760.0 567.0 0.01 -0.1981 -0.6709 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H14 compound treatment 119560.0 -5680.0 -0.18 40440.0 5250.0 0.14 -0.028 -0.1259 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H15 compound treatment 135600.0 10400.0 0.32 39680.0 4490.0 0.12 0.3094 0.906 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H16 compound treatment 106320.0 -18900.0 -0.59 23000.0 -12200.0 -0.32 -0.6385 -0.9583 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H17 compound treatment 115120.0 -10100.0 -0.31 38640.0 3450.0 0.09 -0.1584 -0.4857 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H18 compound treatment 139600.0 14400.0 0.44 41160.0 5970.0 0.16 0.4243 0.9004 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H19 mock treatment 110080.0 -15200.0 -0.47 39800.0 4610.0 0.12 -0.2475 -0.5106 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H20 mock treatment 128960.0 3720.0 0.12 38720.0 3530.0 0.09 0.1463 0.9935 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H21 compound treatment 127440.0 2200.0 0.07 32520.0 -2670.0 -0.07 -9.0E-4 -0.0091 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H22 compound treatment 93640.0 -31600.0 -0.98 30920.0 -4270.0 -0.11 -0.7708 -0.7823 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H23 compound treatment 130560.0 5320.0 0.16 37480.0 2290.0 0.06 0.1586 0.905 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 H24 compound treatment 108880.0 -16400.0 -0.51 24680.0 -10500.0 -0.27 -0.5516 -0.9579 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I01 compound treatment 159240.0 34000.0 1.05 29160.0 -6030.0 -0.16 0.6341 0.5953 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I02 compound treatment 127720.0 2480.0 0.08 33760.0 -1430.0 -0.04 0.028 0.3282 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I03 compound treatment 130320.0 5080.0 0.16 33760.0 -1430.0 -0.04 0.085 0.5254 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I04 compound treatment 142080.0 16800.0 0.52 40600.0 5410.0 0.14 0.4683 0.8666 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I05 mock treatment 126640.0 1400.0 0.04 36840.0 1650.0 0.04 0.061 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I06 mock treatment 129280.0 4040.0 0.13 35920.0 727.0 0.02 0.1019 0.8047 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I07 compound treatment 127480.0 2240.0 0.07 34760.0 -433.0 -0.01 0.0411 0.585 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I08 compound treatment 120080.0 -5160.0 -0.16 33320.0 -1870.0 -0.05 -0.1474 -0.8824 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I09 compound treatment 126600.0 1360.0 0.04 35200.0 7.27 0.0 0.03 0.7103 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I10 compound treatment 136120.0 10900.0 0.34 33160.0 -2030.0 -0.05 0.201 0.5891 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I11 compound treatment 118400.0 -6840.0 -0.21 32840.0 -2350.0 -0.06 -0.1931 -0.8754 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I12 compound treatment 124600.0 -639.0 -0.02 37720.0 2530.0 0.07 0.0324 0.4729 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I13 compound treatment 107120.0 -18100.0 -0.56 33720.0 -1470.0 -0.04 -0.424 -0.7536 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I14 compound treatment 107920.0 -17300.0 -0.54 29680.0 -5510.0 -0.14 -0.4807 -0.8655 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I15 compound treatment 126680.0 1440.0 0.04 40000.0 4810.0 0.12 0.1199 0.9039 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I16 compound treatment 122000.0 -3240.0 -0.1 30720.0 -4470.0 -0.12 -0.1531 -0.9973 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I17 compound treatment 115000.0 -10200.0 -0.32 34960.0 -233.0 -0.01 -0.2286 -0.7205 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I18 compound treatment 33280.0 -92000.0 -2.85 7440.0 -27800.0 -0.72 -2.5247 -0.859 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I19 compound treatment 134720.0 9480.0 0.29 36960.0 1770.0 0.05 0.2402 0.8078 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I20 compound treatment 130800.0 5560.0 0.17 33560.0 -1630.0 -0.04 0.0918 0.5176 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I21 mock treatment 145240.0 20000.0 0.62 40080.0 4890.0 0.13 0.528 0.8347 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I22 mock treatment 134440.0 9200.0 0.29 41760.0 6570.0 0.17 0.3222 0.9699 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I23 compound treatment 131080.0 5840.0 0.18 34000.0 -1190.0 -0.03 0.1061 0.5776 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 I24 compound treatment 93320.0 -31900.0 -0.99 19920.0 -15300.0 -0.4 -0.9799 -0.9196 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J01 compound treatment 143600.0 18400.0 0.57 31840.0 -3350.0 -0.09 0.3407 0.5919 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J02 compound treatment 103160.0 -22100.0 -0.68 25400.0 -9790.0 -0.25 -0.6637 -0.9092 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J03 compound treatment 112200.0 -13000.0 -0.4 46760.0 11600.0 0.3 -0.0732 -0.1453 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J04 compound treatment 138160.0 12900.0 0.4 46240.0 11000.0 0.29 0.4861 0.9867 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J05 mock treatment 119760.0 -5480.0 -0.17 48000.0 12800.0 0.33 0.1153 0.3085 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J06 mock treatment 134440.0 9200.0 0.29 40680.0 5490.0 0.14 0.3024 0.9487 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J07 compound treatment 141480.0 16200.0 0.5 43720.0 8530.0 0.22 0.5125 0.9321 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J08 compound treatment 85520.0 -39700.0 -1.23 4160.0 -31000.0 -0.81 -1.4404 -0.979 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J09 compound treatment 102640.0 -22600.0 -0.7 33920.0 -1270.0 -0.03 -0.5185 -0.7397 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J10 compound treatment 118880.0 -6360.0 -0.2 36000.0 807.0 0.02 -0.1245 -0.6283 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J11 compound treatment 115440.0 -9800.0 -0.3 35640.0 447.0 0.01 -0.2065 -0.6795 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J12 compound treatment 103440.0 -21800.0 -0.68 12920.0 -22300.0 -0.58 -0.8868 -0.997 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J13 compound treatment 118640.0 -6600.0 -0.2 31560.0 -3630.0 -0.09 -0.2113 -0.9384 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J14 compound treatment 103800.0 -21400.0 -0.66 10320.0 -24900.0 -0.65 -0.9267 -0.9999 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J15 compound treatment 117880.0 -7360.0 -0.23 34240.0 -953.0 -0.02 -0.1787 -0.7793 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J16 compound treatment 71160.0 -54100.0 -1.68 4680.0 -30500.0 -0.79 -1.7454 -0.9416 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J17 compound treatment 114760.0 -10500.0 -0.32 35840.0 647.0 0.02 -0.2177 -0.6696 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J18 compound treatment 94600.0 -30600.0 -0.95 10640.0 -24600.0 -0.64 -1.1224 -0.9813 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J19 compound treatment 125680.0 441.0 0.01 33880.0 -1310.0 -0.03 -0.0145 -0.3935 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J20 compound treatment 106520.0 -18700.0 -0.58 8920.0 -26300.0 -0.68 -0.8928 -0.9967 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J21 mock treatment 125720.0 481.0 0.01 37000.0 1810.0 0.05 0.0437 0.8879 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J22 mock treatment 114440.0 -10800.0 -0.33 38040.0 2850.0 0.07 -0.1843 -0.5378 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J23 compound treatment 118480.0 -6760.0 -0.21 30880.0 -4310.0 -0.11 -0.2273 -0.9571 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 J24 compound treatment 55760.0 -69500.0 -2.15 4680.0 -30500.0 -0.79 -2.0828 -0.9079 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K01 compound treatment 125960.0 721.0 0.02 17560.0 -17600.0 -0.46 -0.3082 -0.6718 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K02 compound treatment 123680.0 -1560.0 -0.05 33720.0 -1470.0 -0.04 -0.0612 -0.9933 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K03 compound treatment 100440.0 -24800.0 -0.77 15880.0 -19300.0 -0.5 -0.8982 -0.9787 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K04 compound treatment 119560.0 -5680.0 -0.18 29600.0 -5590.0 -0.15 -0.2272 -0.9955 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K05 compound treatment 113920.0 -11300.0 -0.35 30360.0 -4830.0 -0.13 -0.3368 -0.9041 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K06 compound treatment 130560.0 5320.0 0.16 27600.0 -7590.0 -0.2 -0.0229 -0.0891 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K07 mock treatment 109680.0 -15600.0 -0.48 35880.0 687.0 0.02 -0.3283 -0.6804 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K08 mock treatment 109400.0 -15800.0 -0.49 33520.0 -1670.0 -0.04 -0.3778 -0.7667 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K09 compound treatment 119320.0 -5920.0 -0.18 18920.0 -16300.0 -0.42 -0.4287 -0.9301 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K10 compound treatment 44480.0 -80800.0 -2.5 8240.0 -27000.0 -0.7 -2.2646 -0.8715 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K11 compound treatment 138600.0 13400.0 0.41 25040.0 -10200.0 -0.26 0.1062 0.2163 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K12 compound treatment 138160.0 12900.0 0.4 29360.0 -5830.0 -0.15 0.1759 0.411 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K13 compound treatment 120000.0 -5240.0 -0.16 31240.0 -3950.0 -0.1 -0.1874 -0.9756 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K14 compound treatment 118120.0 -7120.0 -0.22 30760.0 -4430.0 -0.12 -0.2374 -0.9541 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K15 mock treatment 109640.0 -15600.0 -0.48 31720.0 -3470.0 -0.09 -0.4056 -0.8249 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K16 mock treatment 128000.0 2760.0 0.09 29480.0 -5710.0 -0.15 -0.0445 -0.2596 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K17 compound treatment 123640.0 -1600.0 -0.05 32960.0 -2230.0 -0.06 -0.0761 -0.9969 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K18 compound treatment 126240.0 1000.0 0.03 30760.0 -4430.0 -0.12 -0.0595 -0.4989 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K19 compound treatment 124560.0 -679.0 -0.02 37120.0 1930.0 0.05 0.0205 0.378 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K20 compound treatment 120920.0 -4320.0 -0.13 32720.0 -2470.0 -0.06 -0.1401 -0.9435 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K21 compound treatment 119960.0 -5280.0 -0.16 40320.0 5130.0 0.13 -0.0215 -0.1017 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K22 compound treatment 114600.0 -10600.0 -0.33 31120.0 -4070.0 -0.11 -0.3079 -0.8894 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K23 mock treatment 117400.0 -7840.0 -0.24 36440.0 1250.0 0.03 -0.1488 -0.6074 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 K24 mock treatment 144280.0 19000.0 0.59 27600.0 -7590.0 -0.2 0.2777 0.4464 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L01 compound treatment 141640.0 16400.0 0.51 35080.0 -113.0 0.0 0.3573 0.703 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L02 compound treatment 66800.0 -58400.0 -1.81 3120.0 -32100.0 -0.83 -1.8696 -0.938 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L03 compound treatment 143880.0 18600.0 0.58 41240.0 6050.0 0.16 0.5195 0.8679 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L04 compound treatment 86000.0 -39200.0 -1.22 8840.0 -26400.0 -0.68 -1.3439 -0.9631 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L05 compound treatment 143600.0 18400.0 0.57 47000.0 11800.0 0.31 0.6192 0.958 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L06 compound treatment 120600.0 -4640.0 -0.14 17080.0 -18100.0 -0.47 -0.4344 -0.8828 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L07 mock treatment 127720.0 2480.0 0.08 35840.0 647.0 0.02 0.0662 0.8419 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L08 mock treatment 114200.0 -11000.0 -0.34 38440.0 3250.0 0.08 -0.1822 -0.5172 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L09 compound treatment 150520.0 25300.0 0.78 38080.0 2890.0 0.08 0.6069 0.7713 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L10 compound treatment 94800.0 -30400.0 -0.94 3200.0 -32000.0 -0.83 -1.2547 -0.998 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L11 compound treatment 122880.0 -2360.0 -0.07 34800.0 -393.0 -0.01 -0.0589 -0.7981 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L12 compound treatment 155680.0 30400.0 0.94 29840.0 -5350.0 -0.14 0.5686 0.5964 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L13 compound treatment 126040.0 801.0 0.02 33120.0 -2070.0 -0.05 -0.0205 -0.3463 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L14 compound treatment 123760.0 -1480.0 -0.05 12640.0 -22600.0 -0.59 -0.4468 -0.7601 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L15 mock treatment 118360.0 -6880.0 -0.21 30520.0 -4670.0 -0.12 -0.2366 -0.9644 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L16 mock treatment 127960.0 2720.0 0.08 33480.0 -1710.0 -0.04 0.0281 0.2953 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L17 compound treatment 114600.0 -10600.0 -0.33 32640.0 -2550.0 -0.07 -0.28 -0.8327 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L18 compound treatment 108480.0 -16800.0 -0.52 18040.0 -17200.0 -0.45 -0.6823 -0.9971 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L19 compound treatment 120960.0 -4280.0 -0.13 31840.0 -3350.0 -0.09 -0.1553 -0.9792 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L20 compound treatment 80520.0 -44700.0 -1.39 8640.0 -26600.0 -0.69 -1.4676 -0.9482 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L21 compound treatment 129000.0 3760.0 0.12 30920.0 -4270.0 -0.11 0.0039 0.0242 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L22 compound treatment 47120.0 -78100.0 -2.42 2960.0 -32200.0 -0.84 -2.3037 -0.8995 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L23 mock treatment 114080.0 -11200.0 -0.35 31600.0 -3590.0 -0.09 -0.3105 -0.867 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 L24 mock treatment 135080.0 9840.0 0.3 23440.0 -11800.0 -0.31 -3.0E-4 -7.0E-4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M01 compound treatment 157560.0 32300.0 1.0 32320.0 -2870.0 -0.07 0.6554 0.6526 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M02 compound treatment 121480.0 -3760.0 -0.12 33640.0 -1550.0 -0.04 -0.1109 -0.8996 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M03 compound treatment 120800.0 -4440.0 -0.14 31720.0 -3470.0 -0.09 -0.1611 -0.9791 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M04 compound treatment 128480.0 3240.0 0.1 24240.0 -11000.0 -0.28 -0.1302 -0.4315 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M05 compound treatment 121920.0 -3320.0 -0.1 32160.0 -3030.0 -0.08 -0.1284 -0.9914 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M06 compound treatment 136840.0 11600.0 0.36 31200.0 -3990.0 -0.1 0.1808 0.4833 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M07 compound treatment 116320.0 -8920.0 -0.28 29400.0 -5790.0 -0.15 -0.3018 -0.9592 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M08 compound treatment 131320.0 6080.0 0.19 25480.0 -9710.0 -0.25 -0.0452 -0.1436 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M09 mock treatment 123080.0 -2160.0 -0.07 29200.0 -5990.0 -0.16 -0.1574 -0.9288 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M10 mock treatment 129520.0 4280.0 0.13 26760.0 -8430.0 -0.22 -0.0611 -0.2387 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M11 compound treatment 105440.0 -19800.0 -0.61 24960.0 -10200.0 -0.27 -0.6218 -0.93 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M12 compound treatment 116280.0 -8960.0 -0.28 26120.0 -9070.0 -0.24 -0.363 -0.9967 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M13 mock treatment 111960.0 -13300.0 -0.41 30000.0 -5190.0 -0.13 -0.3863 -0.8922 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M14 mock treatment 127160.0 1920.0 0.06 29160.0 -6030.0 -0.16 -0.0687 -0.41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M15 compound treatment 106600.0 -18600.0 -0.58 30560.0 -4630.0 -0.12 -0.4935 -0.8365 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M16 compound treatment 112320.0 -12900.0 -0.4 31920.0 -3270.0 -0.09 -0.3432 -0.8386 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M17 compound treatment 128920.0 3680.0 0.11 34200.0 -993.0 -0.03 0.0624 0.5337 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M18 compound treatment 123840.0 -1400.0 -0.04 32720.0 -2470.0 -0.06 -0.0761 -0.9817 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M19 mock treatment 114200.0 -11000.0 -0.34 38800.0 3610.0 0.09 -0.1756 -0.4951 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M20 compound treatment 125960.0 721.0 0.02 32720.0 -2470.0 -0.06 -0.0296 -0.4357 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M21 mock treatment 110920.0 -14300.0 -0.44 31480.0 -3710.0 -0.1 -0.3819 -0.8412 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M22 compound treatment 125640.0 401.0 0.01 32240.0 -2950.0 -0.08 -0.0455 -0.585 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M23 mock treatment 109520.0 -15700.0 -0.49 32320.0 -2870.0 -0.07 -0.3972 -0.8061 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 M24 compound treatment 56920.0 -68300.0 -2.12 16360.0 -18800.0 -0.49 -1.8428 -0.8482 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N01 compound treatment 158600.0 33400.0 1.03 36240.0 1050.0 0.03 0.7502 0.7255 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N02 compound treatment 19760.0 -105000.0 -3.27 3040.0 -32200.0 -0.84 -2.9017 -0.8602 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N03 compound treatment 138160.0 12900.0 0.4 40040.0 4850.0 0.13 0.3721 0.8867 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N04 compound treatment 105440.0 -19800.0 -0.61 36560.0 1370.0 0.04 -0.4087 -0.665 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N05 compound treatment 150880.0 25600.0 0.79 32520.0 -2670.0 -0.07 0.5127 0.6428 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N06 compound treatment 147600.0 22400.0 0.69 23120.0 -12100.0 -0.31 0.2681 0.3525 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N07 compound treatment 142040.0 16800.0 0.52 33800.0 -1390.0 -0.04 0.3425 0.6564 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N08 compound treatment 133520.0 8280.0 0.26 20400.0 -14800.0 -0.38 -0.0904 -0.1955 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N09 mock treatment 118280.0 -6960.0 -0.22 34040.0 -1150.0 -0.03 -0.1736 -0.7977 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N10 mock treatment 120040.0 -5200.0 -0.16 28600.0 -6590.0 -0.17 -0.235 -0.9995 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N11 compound treatment 108000.0 -17200.0 -0.53 28040.0 -7150.0 -0.19 -0.5091 -0.9002 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N12 compound treatment 74480.0 -50800.0 -1.57 4680.0 -30500.0 -0.79 -1.6727 -0.9497 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N13 mock treatment 114480.0 -10800.0 -0.33 31760.0 -3430.0 -0.09 -0.2988 -0.8658 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N14 mock treatment 149320.0 24100.0 0.75 31880.0 -3310.0 -0.09 0.4667 0.6214 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N15 compound treatment 111160.0 -14100.0 -0.44 33440.0 -1750.0 -0.05 -0.3407 -0.7767 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N16 compound treatment 133120.0 7880.0 0.24 35120.0 -72.7 0.0 0.1713 0.7016 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N17 compound treatment 117800.0 -7440.0 -0.23 31560.0 -3630.0 -0.09 -0.2297 -0.9223 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N18 compound treatment 93280.0 -32000.0 -0.99 6760.0 -28400.0 -0.74 -1.2226 -0.9896 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N19 compound treatment 115280.0 -9960.0 -0.31 32000.0 -3190.0 -0.08 -0.2769 -0.8664 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N20 compound treatment 123160.0 -2080.0 -0.06 17600.0 -17600.0 -0.46 -0.3688 -0.7989 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N21 compound treatment 131040.0 5800.0 0.18 39240.0 4050.0 0.11 0.2015 0.9674 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N22 compound treatment 90440.0 -34800.0 -1.08 14400.0 -20800.0 -0.54 -1.1444 -0.9489 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N23 compound treatment 132360.0 7120.0 0.22 37000.0 1810.0 0.05 0.1892 0.8388 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 N24 compound treatment 7760.0 -117000.0 -3.64 1880.0 -33300.0 -0.87 -3.1859 -0.8515 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O01 mock treatment 169160.0 43900.0 1.36 25920.0 -9270.0 -0.24 0.7919 0.573 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O02 compound treatment 136040.0 10800.0 0.33 30560.0 -4630.0 -0.12 0.1515 0.4261 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O03 mock treatment 103160.0 -22100.0 -0.68 30680.0 -4510.0 -0.12 -0.5666 -0.8164 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O04 mock treatment 116520.0 -8720.0 -0.27 30760.0 -4430.0 -0.12 -0.2725 -0.9278 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O05 mock treatment 111920.0 -13300.0 -0.41 29560.0 -5630.0 -0.15 -0.3953 -0.9028 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O06 mock treatment 90760.0 -34500.0 -1.07 28520.0 -6670.0 -0.17 -0.878 -0.8112 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O07 mock treatment 107280.0 -18000.0 -0.56 24040.0 -11200.0 -0.29 -0.5984 -0.9538 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O08 mock treatment 108920.0 -16300.0 -0.51 31040.0 -4150.0 -0.11 -0.4338 -0.8391 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O09 mock treatment 100240.0 -25000.0 -0.77 28680.0 -6510.0 -0.17 -0.6674 -0.8417 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O10 mock treatment 99880.0 -25400.0 -0.79 27920.0 -7270.0 -0.19 -0.6892 -0.8528 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O11 mock treatment 105000.0 -20200.0 -0.63 26520.0 -8670.0 -0.23 -0.6028 -0.9046 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O12 mock treatment 103800.0 -21400.0 -0.66 26400.0 -8790.0 -0.23 -0.6313 -0.8986 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O13 mock treatment 97720.0 -27500.0 -0.85 27840.0 -7350.0 -0.19 -0.738 -0.8446 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O14 mock treatment 112800.0 -12400.0 -0.39 26320.0 -8870.0 -0.23 -0.4355 -0.9698 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O15 mock treatment 118400.0 -6840.0 -0.21 29080.0 -6110.0 -0.16 -0.2621 -0.9899 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O16 mock treatment 116680.0 -8560.0 -0.27 25360.0 -9830.0 -0.26 -0.3682 -0.9998 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O17 mock treatment 111920.0 -13300.0 -0.41 26960.0 -8230.0 -0.21 -0.4431 -0.9532 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O18 mock treatment 101200.0 -24000.0 -0.74 26560.0 -8630.0 -0.22 -0.6853 -0.881 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O19 mock treatment 123400.0 -1840.0 -0.06 26720.0 -8470.0 -0.22 -0.196 -0.8617 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O20 mock treatment 112600.0 -12600.0 -0.39 31280.0 -3910.0 -0.1 -0.3488 -0.8621 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O21 mock treatment 97080.0 -28200.0 -0.87 31760.0 -3430.0 -0.09 -0.68 -0.7754 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O22 mock treatment 108800.0 -16400.0 -0.51 30480.0 -4710.0 -0.12 -0.4468 -0.8528 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O23 mock treatment 102720.0 -22500.0 -0.7 28000.0 -7190.0 -0.19 -0.6255 -0.866 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 O24 mock treatment 153280.0 28000.0 0.87 20560.0 -14600.0 -0.38 0.3455 0.3643 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P01 compound treatment 107320.0 -17900.0 -0.56 26760.0 -8430.0 -0.22 -0.5475 -0.9173 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P02 compound treatment 124040.0 -1200.0 -0.04 15840.0 -19400.0 -0.5 -0.3818 -0.7573 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P03 compound treatment 117320.0 -7920.0 -0.25 26960.0 -8230.0 -0.21 -0.3248 -0.9977 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P04 compound treatment 97960.0 -27300.0 -0.85 17120.0 -18100.0 -0.47 -0.9297 -0.9615 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P05 compound treatment 129920.0 4680.0 0.15 22920.0 -12300.0 -0.32 -0.1229 -0.3509 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P06 compound treatment 117560.0 -7680.0 -0.24 21600.0 -13600.0 -0.35 -0.418 -0.9815 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P07 compound treatment 108200.0 -17000.0 -0.53 30440.0 -4750.0 -0.12 -0.4606 -0.8496 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P08 compound treatment 107360.0 -17900.0 -0.55 10760.0 -24400.0 -0.63 -0.8406 -0.9977 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P09 compound treatment 102080.0 -23200.0 -0.72 27080.0 -8110.0 -0.21 -0.6565 -0.8777 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P10 compound treatment 114680.0 -10600.0 -0.33 16840.0 -18400.0 -0.48 -0.5685 -0.9831 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P11 mock treatment 103840.0 -21400.0 -0.66 28800.0 -6390.0 -0.17 -0.5863 -0.8577 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P12 mock treatment 85000.0 -40200.0 -1.25 26040.0 -9150.0 -0.24 -1.0498 -0.8271 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P13 compound treatment 108680.0 -16600.0 -0.51 22360.0 -12800.0 -0.33 -0.5986 -0.9782 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P14 compound treatment 108800.0 -16400.0 -0.51 8200.0 -27000.0 -0.7 -0.8561 -0.9877 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P15 compound treatment 114000.0 -11200.0 -0.35 23040.0 -12200.0 -0.32 -0.4695 -0.9988 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P16 compound treatment 95600.0 -29600.0 -0.92 9120.0 -26100.0 -0.68 -1.1284 -0.9888 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P17 compound treatment 104720.0 -20500.0 -0.64 25560.0 -9630.0 -0.25 -0.6265 -0.917 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P18 compound treatment 78240.0 -47000.0 -1.46 7080.0 -28100.0 -0.73 -1.5462 -0.9491 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P19 compound treatment 113400.0 -11800.0 -0.37 23960.0 -11200.0 -0.29 -0.4658 -0.9936 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P20 compound treatment 101760.0 -23500.0 -0.73 8560.0 -26600.0 -0.69 -1.0037 -0.9997 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P21 compound treatment 113160.0 -12100.0 -0.37 25360.0 -9830.0 -0.26 -0.4453 -0.9827 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P22 compound treatment 12880.0 -112000.0 -3.48 1760.0 -33400.0 -0.87 -3.076 -0.8573 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P23 compound treatment 128280.0 3040.0 0.09 23880.0 -11300.0 -0.29 -0.1412 -0.4575 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2130 P24 compound treatment 13600.0 -112000.0 -3.46 2520.0 -32700.0 -0.85 -3.0462 -0.8553 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A01 compound treatment 108640.0 -59200.0 -1.84 108120.0 -43400.0 -1.13 -2.0955 -0.9727 1001670 ACon1_000001 COc1cc(O)c2C(=O)CC(Oc2c1)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A02 compound treatment 158040.0 -9830.0 -0.3 123240.0 -28300.0 -0.74 -0.7354 -0.9238 1023904 ACon1_000002 Oc1ccc2C(=O)c3cc(O)ccc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A03 compound treatment 8960.0 -159000.0 -4.92 6280.0 -145000.0 -3.77 -6.1505 -0.9914 3552049 ACon1_000003 C/C=C(\COC(=O)C)/C(=O)O[C@H]1[C@@H]2[C@H](OC(=O)C2=C)C3C(=C(C)[C@H]1O)C(=O)[C@H]4O[C@]43C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A04 compound treatment 148520.0 -19300.0 -0.6 111120.0 -40400.0 -1.05 -1.1666 -0.9646 1039 ACon1_000004 CC[C@]1(CCCN2CCc3c4[C@@H]21)CC(=O)n4c5ccccc35 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A05 compound treatment 158840.0 -9030.0 -0.28 75240.0 -76300.0 -1.98 -1.5997 -0.7989 3559511 ACon1_000005 COC(=O)CC(=O)OC[C@@]1(C)CCC[C@]2(C)[C@H]3CC[C@]4(C)C[C@@]3(CCC12)C=C4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A06 compound treatment 72480.0 -95400.0 -2.96 64600.0 -86900.0 -2.26 -3.6873 -0.9912 3551992 ACon1_000006 C/C/1=C\CCC2=CC(C\C(=C\C3OC(=O)C(=C)C3CC1)\C)OC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A07 compound treatment 93440.0 -74400.0 -2.31 67920.0 -83600.0 -2.17 -3.1671 -0.9996 3189572 ACon1_000007 CN1Cc2c3OCOc3ccc2[C@H]4[C@@H](O)Cc5cc6OCOc6cc5[C@H]41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A08 compound treatment 197600.0 29700.0 0.92 96480.0 -55100.0 -1.43 -0.3603 -0.2117 1116885 ACon1_000008 CCC(C)C1NC(=O)C(=C1O)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A09 compound treatment 175800.0 7930.0 0.25 103320.0 -48200.0 -1.25 -0.7122 -0.5578 3559537 ACon1_000009 C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2C[C@]3(C)[C@@H](O)[C@@H](O)CC13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A10 compound treatment 199560.0 31700.0 0.98 99080.0 -52500.0 -1.36 -0.2696 -0.1605 3559847 ACon1_000010 OC[C@H]1O[C@@H](OCCC(=O)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A11 compound treatment 196400.0 28500.0 0.88 138520.0 -13000.0 -0.34 0.3858 0.4075 3559600 ACon1_000011 COc1ccc2oc(c(O)c(=O)c2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A12 compound treatment 132560.0 -35300.0 -1.09 69800.0 -81700.0 -2.12 -2.2755 -0.9524 3557478 ACon1_000012 CC(=CCc1c(O)ccc2C(=O)CC(Oc12)c3ccc(O)c(O)c3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A13 mock treatment 161080.0 -6790.0 -0.21 148720.0 -2830.0 -0.07 -0.2006 -0.9008 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A14 mock treatment 177320.0 9450.0 0.29 140360.0 -11200.0 -0.29 0.0016 0.0038 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A15 compound treatment 177920.0 10100.0 0.31 126640.0 -24900.0 -0.65 -0.2373 -0.3305 1138815 ACon1_000013 COc1cccc2OC(CC(=O)c12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A16 compound treatment 130880.0 -37000.0 -1.15 62200.0 -89300.0 -2.32 -2.4519 -0.9471 3553257 ACon1_000014 CC(=O)N(O)CCCC1NC(=O)CNC(=O)CNC(=O)CNC(=O)C(CCCN(O)C(=O)C)NC(=O)C(CCCN(O)C(=O)C)NC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A17 compound treatment 186200.0 18300.0 0.57 63840.0 -87700.0 -2.28 -1.2097 -0.5151 1527185 ACon1_000015 COc1ccccc1c2cc(=O)c3ccccc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A18 compound treatment 182040.0 14200.0 0.44 30280.0 -121000.0 -3.15 -1.9175 -0.6027 3558773 ACon1_000016 CC1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A19 compound treatment 160840.0 -7030.0 -0.22 108560.0 -43000.0 -1.12 -0.9437 -0.8293 3559667 ACon1_000017 CCC1=CC2CN3CCc4c([nH]c5ccccc45)[C@@](C2)([C@H]31)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A20 compound treatment 195360.0 27500.0 0.85 165440.0 13900.0 0.36 0.8576 0.9269 3558449 ACon1_000018 C[C@@H]1OC(OC[C@H]2O[C@@H](Oc3cc(O)c4c(=O)cc(oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A21 compound treatment 127160.0 -40700.0 -1.26 137160.0 -14400.0 -0.37 -1.1562 -0.8789 1530 ACon1_000019 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A22 compound treatment 162320.0 -5550.0 -0.17 169360.0 17800.0 0.46 0.2057 0.4168 3559224 ACon1_000020 CC(=O)c1ccc2OC(Cc2c1)C(=C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A23 compound treatment 152640.0 -15200.0 -0.47 162440.0 10900.0 0.28 -0.1335 -0.2426 3554786 ACon1_000021 COc1cc(/C=C/2\Oc3cc(O)ccc3C2=O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 A24 compound treatment 100240.0 -67600.0 -2.1 108120.0 -43400.0 -1.13 -2.2795 -0.9578 3559348 ACon1_000022 CC(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccccc2COC(=O)C3(O)C=CCCC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B01 compound treatment 5520.0 -162000.0 -5.03 4600.0 -147000.0 -3.82 -6.2567 -0.9907 3557968 ACon1_000023 CC(=CCc1c(O)c(CC=C(C)C)c2occ(c3ccc(O)cc3)c(=O)c2c1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B02 compound treatment 8800.0 -159000.0 -4.93 6560.0 -145000.0 -3.77 -6.1488 -0.9912 3555955 ACon1_000024 OCC(=C)C(=O)O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3[C@H](CC2=C)OC(=O)C(=C)CO)C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B03 compound treatment 191000.0 23100.0 0.72 134680.0 -16900.0 -0.44 0.1969 0.2344 3552206 ACon1_000025 C[C@@]1(CO)C(O)CC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B04 compound treatment 101920.0 -65900.0 -2.04 78440.0 -73100.0 -1.9 -2.788 -0.9993 3554785 ACon1_000026 COc1c2occ(COC(=O)C)c2c(C=O)c3c(C)cccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B05 compound treatment 173320.0 5450.0 0.17 91440.0 -60100.0 -1.56 -0.9848 -0.6269 3557493 ACon1_000027 CC1(C)CCCC2(C3CCC4CC3(CC4(O)CO)CCC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B06 compound treatment 171920.0 4050.0 0.13 113440.0 -38100.0 -0.99 -0.6113 -0.6125 3614336 ACon1_000028 CC[C@@H]1OC(=O)[C@@H](C)[C@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@@H](C)[C@H](O)[C@](C)(C[C@H](C)C(=O)[C@@H](C)[C@H](O)[C@@]1(C)O)O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B07 compound treatment 182800.0 14900.0 0.46 94440.0 -57100.0 -1.48 -0.722 -0.4645 3557846 ACon1_000029 O[C@@H]1[C@@H](O)[C@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)O[C@@H]([C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B08 compound treatment 163520.0 -4350.0 -0.13 81560.0 -70000.0 -1.82 -1.3811 -0.7574 3557557 ACon1_000030 C/C(=C/CC\C(=C\CC\C(=C\CC/C(=C\CO)/CO)\C)\C)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B09 compound treatment 181280.0 13400.0 0.42 78200.0 -73300.0 -1.91 -1.0537 -0.5402 3554854 ACon1_000031 COc1cc(C)cc(C(=O)O)c1C2=C(O)C(=O)c3c(O)cccc3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B10 compound treatment 149920.0 -17900.0 -0.56 99200.0 -52300.0 -1.36 -1.355 -0.9221 3553850 ACon1_000032 CC1(C)C[C@H](O)C[C@@]2(C)[C@H]1[C@H](O)C=C3COC(=O)[C@@]32O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B11 compound treatment 134320.0 -33500.0 -1.04 75640.0 -75900.0 -1.97 -2.1296 -0.9552 2060482 ACon1_000033 CC(C)c1cc2CCC3C(C)(C)CCC[C@]3(C(=O)O)c2c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B12 compound treatment 201640.0 33800.0 1.05 128720.0 -22800.0 -0.59 0.3206 0.2665 3559288 ACon1_000034 CC1OC(OC2C(O)C(O[C@H]3[C@H](C)O[C@@H](OC4C(O)C(O)COC4OC(=O)[C@@]56CCC(C)(C)CC6C7=CCC8[C@@]9(C)C[C@H](O)[C@H](OC%10OC(CO)C(O)C(O)C%10O)[C@@](C)(CO)C9[C@H](O)C[C@@]8(C)[C@]7(C)CC5)[C@H](O)[C@@H]3O)OCC2O[C@H]%11OC[C@](O)(CO)[C@H]%11O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B13 mock treatment 147120.0 -20700.0 -0.64 137040.0 -14500.0 -0.38 -0.7211 -0.9677 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B14 mock treatment 157640.0 -10200.0 -0.32 138760.0 -12800.0 -0.33 -0.459 -0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B15 compound treatment 35000.0 -133000.0 -4.12 19480.0 -132000.0 -3.43 -5.3374 -0.9959 3559345 ACon1_000035 CC(=CCc1cc(cc(O)c1O)c2coc3c(CC=C(C)C)c(O)cc(O)c3c2=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B16 compound treatment 136040.0 -31800.0 -0.99 93880.0 -57700.0 -1.5 -1.7568 -0.9794 3554649 ACon1_000036 COC(=O)C(=C)[C@]1(O[C@]2(C)CC1=O)[C@H](C[C@@]3(C)OC(=O)/C(=C/C)/[C@]3(O)CC2)OC(=O)C(CO)CN4CCCC4C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B17 compound treatment 166240.0 -1630.0 -0.05 106960.0 -44600.0 -1.16 -0.8548 -0.7372 3559460 ACon1_000037 CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B18 compound treatment 143600.0 -24300.0 -0.75 143360.0 -8190.0 -0.21 -0.6821 -0.8729 3557695 ACon1_000038 COC(=O)[C@@]1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6OC[C@@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B19 compound treatment 150880.0 -17000.0 -0.53 127040.0 -24500.0 -0.64 -0.8224 -0.9955 3558409 ACon1_000039 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B20 compound treatment 143640.0 -24200.0 -0.75 126000.0 -25500.0 -0.66 -1.0002 -0.9981 3557530 ACon1_000040 COC(=O)C(=C)[C@@H]1[C@@H](O)C[C@@]2(COC(=O)C(=C)[C@@H]2[C@H]1O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B21 compound treatment 144320.0 -23500.0 -0.73 144320.0 -7230.0 -0.19 -0.6487 -0.861 3559391 ACon1_000041 COc1cc(cc(OC)c1O)C2C(CO[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)O)C(CO)Cc4cc(OC)c(O)c(O)c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B22 compound treatment 35400.0 -132000.0 -4.1 27360.0 -124000.0 -3.23 -5.1839 -0.9929 3557713 ACon1_000042 CO[C@H]1[C@@H](O)[C@@H](C)O[C@@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4(O)CC(OC(=O)C)C3=C2)C6=CC(=O)OC6)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B23 compound treatment 173120.0 5250.0 0.16 133240.0 -18300.0 -0.48 -0.2213 -0.4401 3559546 ACon1_000043 CC12CCC=C(CO)C2CC3C(C1)OC(=O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 B24 compound treatment 139400.0 -28500.0 -0.88 122760.0 -28800.0 -0.75 -1.1526 -0.9966 3557636 ACon1_000044 OC(=O)[C@@H](OC(=O)/C=C/c1ccc(O)c(O)c1)[C@](O)(Cc2ccc(O)c(O)c2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C01 compound treatment 120960.0 -46900.0 -1.45 104560.0 -47000.0 -1.22 -1.891 -0.9962 3558824 ACon1_000045 OCC(=C)C(=O)O[C@H]1CC(=C)[C@@H]2C[C@H](O)C(=C)[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C02 compound treatment 186160.0 18300.0 0.57 117520.0 -34000.0 -0.88 -0.2244 -0.2136 3559748 ACon1_000046 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C03 compound treatment 162440.0 -5430.0 -0.17 126160.0 -25400.0 -0.66 -0.5853 -0.8598 831758 ACon1_000047 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C04 compound treatment 139880.0 -28000.0 -0.87 99160.0 -52400.0 -1.36 -1.5757 -0.9763 1054577 ACon1_000048 COc1cc(cc(OC)c1OC)c2cc(=O)c3c(O)c(OC)c(OC)c(OC)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C05 compound treatment 184360.0 16500.0 0.51 133160.0 -18400.0 -0.48 0.0235 0.0336 3558524 ACon1_000049 COc1c(O)c2c(=O)c(O)c(oc2c(OC)c1OC)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C06 compound treatment 158720.0 -9150.0 -0.28 142440.0 -9110.0 -0.24 -0.3677 -0.996 3559371 ACon1_000050 COC(=O)C1=CO[C@@H](OC2OC(O)C(O)C(O)C2CO)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C07 compound treatment 14920.0 -153000.0 -4.74 9000.0 -143000.0 -3.7 -5.9699 -0.9926 3559455 ACon1_000051 COc1cc(/C=C/C(=O)OC2CC3CCC2(C)C3(C)C)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C08 compound treatment 175200.0 7330.0 0.23 131960.0 -19600.0 -0.51 -0.1992 -0.3574 3559354 ACon1_000052 CC(CCC1(C)C(C)CCC2(C)C1CC(=O)C=C2C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C09 compound treatment 154120.0 -13700.0 -0.43 118440.0 -33100.0 -0.86 -0.9094 -0.9474 3553479 ACon1_000053 CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C10 compound treatment 198920.0 31100.0 0.96 133800.0 -17700.0 -0.46 0.3543 0.3321 3553171 ACon1_000054 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)[C@H]([C@H](O)C(C)(C)C5CC[C@]43C)C(=O)O)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C11 mock treatment 156800.0 -11100.0 -0.34 135000.0 -16500.0 -0.43 -0.5465 -0.9937 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C12 mock treatment 155960.0 -11900.0 -0.37 137440.0 -14100.0 -0.37 -0.52 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C13 compound treatment 146680.0 -21200.0 -0.66 143520.0 -8030.0 -0.21 -0.6117 -0.888 1016235 ACon1_000055 O=c1cc(oc2ccccc12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C14 compound treatment 145480.0 -22400.0 -0.69 130800.0 -20700.0 -0.54 -0.8717 -0.9922 3553953 ACon1_000056 CC12CC3(CC2C1CC34)CC(O)C5C(CO)(CO)CC(=O)CC45C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C15 mock treatment 138240.0 -29600.0 -0.92 128000.0 -23500.0 -0.61 -1.0817 -0.9806 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C16 mock treatment 125360.0 -42500.0 -1.32 123440.0 -28100.0 -0.73 -1.4477 -0.9613 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C17 compound treatment 144440.0 -23400.0 -0.73 112000.0 -39500.0 -1.03 -1.2398 -0.9855 1134 ACon1_000057 CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C18 compound treatment 140800.0 -27100.0 -0.84 109920.0 -41600.0 -1.08 -1.3578 -0.9921 3557809 ACon1_000058 COc1cc(/C=C/CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C19 compound treatment 13080.0 -155000.0 -4.8 9320.0 -142000.0 -3.7 -6.0044 -0.9917 3559685 ACon1_000059 COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)CCc2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C20 compound treatment 144600.0 -23300.0 -0.72 79360.0 -72200.0 -1.88 -1.836 -0.9137 3559829 ACon1_000060 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C21 compound treatment 166000.0 -1870.0 -0.06 122840.0 -28700.0 -0.75 -0.5683 -0.7596 297849 ACon1_000061 COc1ccc2c(c1)[nH]c3c(C)nccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C22 compound treatment 165840.0 -2030.0 -0.06 103200.0 -48300.0 -1.26 -0.9327 -0.7415 3559835 ACon1_000062 COc1cc2ccc(=O)oc2c(CC=C(C)C)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C23 compound treatment 39200.0 -129000.0 -3.99 17680.0 -134000.0 -3.48 -5.2785 -0.9977 3559675 ACon1_000063 Oc1ccc(cc1)[C@@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2[C@H]4[C@@H](Oc5cc(O)cc(O)c5C4=O)c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 C24 compound treatment 131280.0 -36600.0 -1.13 110480.0 -41100.0 -1.07 -1.5561 -0.9995 3557563 ACon1_000064 CC(=CC(O)C/C(=C/COc1ccc2ccc(=O)oc2c1)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D01 compound treatment 97760.0 -70100.0 -2.17 92560.0 -59000.0 -1.53 -2.6197 -0.9854 4614 ACon1_000065 CCCCCCC/C=C\[C@H](O)C#CC#C[C@@H](O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D02 compound treatment 24920.0 -143000.0 -4.43 23880.0 -128000.0 -3.32 -5.4774 -0.9899 3559481 ACon1_000066 C/C/1=C\[C@H]2OC(=O)C(=C)C2[C@@H](C\C(=C\CC1)\C)OC(=O)\C(=C\CO)\CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D03 compound treatment 179440.0 11600.0 0.36 130360.0 -21200.0 -0.55 -0.1357 -0.2065 3558310 ACon1_000067 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D04 compound treatment 21120.0 -147000.0 -4.55 16240.0 -135000.0 -3.52 -5.7011 -0.9919 3559638 ACon1_000068 CC(=CCc1c(O)cc2OC(CC(=O)c2c1O)c3ccc(O)cc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D05 compound treatment 184240.0 16400.0 0.51 167960.0 16400.0 0.43 0.6603 0.9963 3555862 ACon1_000069 OC(=O)CCCCCCC/C=C/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D06 compound treatment 236680.0 68800.0 2.13 164120.0 12600.0 0.33 1.7387 0.806 3559157 ACon1_000070 COc1c(CO)c(O)cc2C(=O)c3ccccc3C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D07 compound treatment 163480.0 -4390.0 -0.14 85240.0 -66300.0 -1.72 -1.3143 -0.7605 3557565 ACon1_000071 CC(=CCC/C(=C/COc1ccc2ccc(=O)oc2c1)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D08 compound treatment 177400.0 9530.0 0.3 140840.0 -10700.0 -0.28 0.0122 0.0299 3554888 ACon1_000072 COc1cc(ccc1O)c2oc3cc(O)c(OC)c(O)c3c(=O)c2O[C@@H]4O[C@H](CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O[C@@H]6OCC(O)(CO)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D09 compound treatment 147840.0 -20000.0 -0.62 123600.0 -27900.0 -0.73 -0.9522 -0.9969 3558155 ACon1_000073 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)c(oc3c2)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D10 compound treatment 199880.0 32000.0 0.99 102880.0 -48700.0 -1.26 -0.1927 -0.1199 3614338 ACon1_000074 CC(C)C(NC(=O)c1ccc(O)cc1)C(=O)N2CCCC2C(=O)Nc3c(O)cccc3C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D11 mock treatment 175760.0 7890.0 0.24 142360.0 -9190.0 -0.24 0.0041 0.0121 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D12 mock treatment 162640.0 -5230.0 -0.16 130680.0 -20900.0 -0.54 -0.4979 -0.8799 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D13 compound treatment 141840.0 -26000.0 -0.81 145120.0 -6430.0 -0.17 -0.6883 -0.8358 1251 ACon1_000075 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D14 compound treatment 156400.0 -11500.0 -0.36 141960.0 -9590.0 -0.25 -0.4274 -0.9849 3554269 ACon1_000076 CCCCCC(O)CC(O)CC(=O)OC(CC(O)CCCCC)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D15 mock treatment 173040.0 5170.0 0.16 135400.0 -16100.0 -0.42 -0.1833 -0.4082 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D16 mock treatment 170960.0 3090.0 0.1 142920.0 -8630.0 -0.22 -0.0907 -0.3721 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D17 compound treatment 175560.0 7690.0 0.24 106280.0 -45300.0 -1.18 -0.6631 -0.5526 3559890 ACon1_000077 COc1c(O)cc2occ(c3ccccc3O)c(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D18 compound treatment 141000.0 -26900.0 -0.83 152720.0 1170.0 0.03 -0.5671 -0.6808 3557697 ACon1_000078 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D19 compound treatment 178520.0 10700.0 0.33 128760.0 -22800.0 -0.59 -0.1852 -0.2733 3557614 ACon1_000079 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D20 compound treatment 93880.0 -74000.0 -2.29 52120.0 -99400.0 -2.58 -3.4477 -0.9982 3554651 ACon1_000080 COC(=O)C(=C)[C@H]1[C@H](O)C2C(=C)C(=O)OC[C@]2(C[C@@H]1OC(=O)C(=C)CO)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D21 compound treatment 160920.0 -6950.0 -0.22 160720.0 9170.0 0.24 0.0163 0.0509 3558580 ACon1_000081 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D22 compound treatment 155360.0 -12500.0 -0.39 127400.0 -24100.0 -0.63 -0.7177 -0.9732 3557892 ACon1_000082 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C)[C@H]3C[C@H](OC(=O)C)[C@](O)(COC(=O)C)[C@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D23 compound treatment 151000.0 -16900.0 -0.52 154440.0 2890.0 0.08 -0.3164 -0.5993 3559584 ACon1_000083 CC1(C)[C@H](O)CC[C@@]2(C)[C@@H]3CC[C@@](C)(CC3=CC[C@H]12)C(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 D24 compound treatment 36720.0 -131000.0 -4.06 25120.0 -126000.0 -3.28 -5.1961 -0.9944 3554996 ACon1_000084 COC1CC(O[C@H]2CC[C@@]3(C)[C@H](CC[C@]4(CC[C@H](C5=CC(=O)OC5)[C@@]6(C)CCC34)C6=O)C2)OC(C)C1OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E01 mock treatment 162640.0 -5230.0 -0.16 122360.0 -29200.0 -0.76 -0.6508 -0.8392 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E02 mock treatment 184320.0 16500.0 0.51 144400.0 -7150.0 -0.19 0.2292 0.4224 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E03 compound treatment 179600.0 11700.0 0.36 149160.0 -2390.0 -0.06 0.2132 0.5781 451 ACon1_000085 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E04 compound treatment 151080.0 -16800.0 -0.52 103280.0 -48300.0 -1.25 -1.2546 -0.924 687 ACon1_000086 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E05 compound treatment 196000.0 28100.0 0.87 133600.0 -17900.0 -0.47 0.2866 0.29 1225 ACon1_000087 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E06 compound treatment 92000.0 -75900.0 -2.35 72720.0 -78800.0 -2.05 -3.1104 -0.9976 3557593 ACon1_000088 C/C(=C/CO)/CC[C@@H]1[C@@](C)(O)CCC2C(C)(C)CCC[C@@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E07 compound treatment 48440.0 -119000.0 -3.7 24840.0 -127000.0 -3.29 -4.9445 -0.9983 3559517 ACon1_000089 C[C@@H]1CC[C@]2(C)[C@H](CCC=C2C)[C@]1(CCc3ccoc3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E08 compound treatment 203520.0 35700.0 1.1 131400.0 -20100.0 -0.52 0.411 0.3362 3557755 ACon1_000090 COc1cc(CCCO)cc2C(CO)C(Oc21)c3ccc(O[C@H]4O[C@H](C)[C@@H](O)[C@H](O)[C@@H]4O)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E09 mock treatment 158760.0 -9110.0 -0.28 128800.0 -22700.0 -0.59 -0.6174 -0.9428 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E10 mock treatment 169160.0 1290.0 0.04 151520.0 -27.5 0.0 0.0278 0.6944 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E11 compound treatment 121440.0 -46400.0 -1.44 45720.0 -106000.0 -2.75 -2.9615 -0.9543 3559616 ACon1_000091 CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E12 compound treatment 152800.0 -15100.0 -0.47 137880.0 -13700.0 -0.36 -0.5812 -0.9909 3557829 ACon1_000092 CC(C)(O)[C@@H]1CC[C@@]2(C)C[C@@H](O)CC(=C)C2C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E13 compound treatment 160600.0 -7270.0 -0.23 144040.0 -7510.0 -0.2 -0.2971 -0.9974 1052342 ACon1_000093 Oc1ccc2c(=O)cc(oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E14 compound treatment 141920.0 -25900.0 -0.8 153200.0 1650.0 0.04 -0.5381 -0.6684 3555904 ACon1_000094 OC[C@H]1O[C@@H](Oc2cc(O)cc3OC(O)(Cc4ccc(O)cc4)C(=O)c32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E15 compound treatment 175000.0 7130.0 0.22 146920.0 -4630.0 -0.12 0.0713 0.2833 3554527 ACon1_000095 COC(=O)[C@@]1(O)C=CC[C@@H]2[C@@]3(C)C[C@H](OC(=O)[C@H]3CC[C@]21C)c4ccoc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E16 compound treatment 176680.0 8810.0 0.27 130080.0 -21500.0 -0.56 -0.2013 -0.3241 3558041 ACon1_000096 O[C@H]1CO[C@@H](OC[C@H]2O[C@@H](OC/C=C/c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E17 mock treatment 155240.0 -12600.0 -0.39 134840.0 -16700.0 -0.43 -0.5836 -0.9987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E18 mock treatment 148040.0 -19800.0 -0.61 134560.0 -17000.0 -0.44 -0.7465 -0.9868 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E19 compound treatment 158280.0 -9590.0 -0.3 132120.0 -19400.0 -0.5 -0.567 -0.968 976 ACon1_000097 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E20 compound treatment 163240.0 -4630.0 -0.14 154920.0 3370.0 0.09 -0.0394 -0.2345 3554687 ACon1_000098 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E21 compound treatment 157160.0 -10700.0 -0.33 127480.0 -24100.0 -0.63 -0.6767 -0.956 3553328 ACon1_000099 CC(=O)O[C@@H]1[C@H]2CC[C@@H]3[C@@]1(C[C@@]2(C)O)C[C@@H](O)[C@@]4(O)[C@@H](C[C@H](O)C4(C)C)[C@]3(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E22 compound treatment 154400.0 -13500.0 -0.42 77480.0 -74100.0 -1.92 -1.6559 -0.8409 3559845 ACon1_000100 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E23 compound treatment 168240.0 374.0 0.01 117120.0 -34400.0 -0.89 -0.6243 -0.6979 1013994 ACon1_000101 Oc1ccc(O)c2C(=O)c3ccccc3C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 E24 compound treatment 127600.0 -40300.0 -1.25 96800.0 -54700.0 -1.42 -1.8881 -0.9979 3554732 ACon1_000102 COC(=O)c1cccc2nc3c(cccc3nc12)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F01 mock treatment 166440.0 -1430.0 -0.04 132760.0 -18800.0 -0.49 -0.3764 -0.768 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F02 mock treatment 173920.0 6050.0 0.19 168400.0 16900.0 0.44 0.4423 0.9284 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F03 compound treatment 199640.0 31800.0 0.98 144240.0 -7310.0 -0.19 0.5619 0.5604 3557765 ACon1_000103 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4cc(O)c(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F04 compound treatment 183640.0 15800.0 0.49 100440.0 -51100.0 -1.33 -0.5934 -0.4194 3559590 ACon1_000104 CC1=CC(=O)C2=C(C)CCC3[C@H](OC(=O)C3=C)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F05 compound treatment 165480.0 -2390.0 -0.07 158720.0 7170.0 0.19 0.0795 0.3965 3557685 ACon1_000105 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F06 compound treatment 174880.0 7010.0 0.22 142960.0 -8590.0 -0.22 -0.0041 -0.0132 3554203 ACon1_000106 CCc1c(O)cc(OC)c2C(=O)C[C@@H](C)Oc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F07 compound treatment 40680.0 -127000.0 -3.94 14600.0 -137000.0 -3.56 -5.3027 -0.9987 3558903 ACon1_000107 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@](C)(CO)C5CC[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F08 compound treatment 174360.0 6490.0 0.2 157160.0 5610.0 0.15 0.2454 0.9875 3557773 ACon1_000108 COc1cc(/C=C/CO)cc(OC)c1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F09 mock treatment 152160.0 -15700.0 -0.49 132560.0 -19000.0 -0.49 -0.693 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F10 mock treatment 145760.0 -22100.0 -0.68 139520.0 -12000.0 -0.31 -0.7053 -0.9368 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F11 compound treatment 190280.0 22400.0 0.69 153840.0 2290.0 0.06 0.5332 0.7649 3559308 ACon1_000109 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](OC(=O)C)[C@@H](O)[C@H]4O)c(oc3c2)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F12 compound treatment 175120.0 7250.0 0.22 132720.0 -18800.0 -0.49 -0.187 -0.3473 1216977 ACon1_000110 CC1(C)Oc2ccc3ccc(=O)oc3c2CC1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F13 compound treatment 179800.0 11900.0 0.37 156880.0 5330.0 0.14 0.3594 0.9103 3559144 ACon1_000111 CC1CCC2(CCC3(C)C(=CCC4C5(C)C[C@@H](O)[C@@H](O)C(C)(CO)C5CCC43C)C2C1(C)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F14 compound treatment 178600.0 10700.0 0.33 153920.0 2370.0 0.06 0.2788 0.8241 3552034 ACon1_000112 C/C=C(\C)/C(=O)OC(\C=C\C(O)C(C)O)C1OC(=O)C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F15 compound treatment 179680.0 11800.0 0.37 144200.0 -7350.0 -0.19 0.1238 0.3 3552812 ACon1_000113 C[C@@H]1OC(O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)/C=C/c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F16 compound treatment 164360.0 -3510.0 -0.11 144600.0 -6950.0 -0.18 -0.2045 -0.9705 3557622 ACon1_000114 COc1ccc(CCC(=O)O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F17 mock treatment 152440.0 -15400.0 -0.48 142360.0 -9190.0 -0.24 -0.5068 -0.9485 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F18 mock treatment 149960.0 -17900.0 -0.55 141200.0 -10300.0 -0.27 -0.5824 -0.9447 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F19 compound treatment 172160.0 4290.0 0.13 139320.0 -12200.0 -0.32 -0.1306 -0.3791 3552693 ACon1_000115 C[C@@H]1CC[C@@]2(CC[C@]3(C)C4=CCC5C(C)(C)[C@H](CC[C@]5(C)C4CC[C@@]3(C)[C@@H]2[C@H]1C)O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F20 compound treatment 158080.0 -9790.0 -0.3 136200.0 -15300.0 -0.4 -0.4964 -0.9909 3554774 ACon1_000116 COc1c(OC/C=C(\C)/CC2OC(=O)C(=C2)C)ccc3ccc(=O)oc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F21 compound treatment 164640.0 -3230.0 -0.1 156600.0 5050.0 0.13 0.0221 0.1342 3559078 ACon1_000117 CC1OC(OC2C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC65C)C(=O)OC8OC(CO)C(O)C(O)C8O)C3(C)C)OC(C2O)C(=O)O)C(OC9OC(CO)C(O)C(O)C9O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F22 compound treatment 176360.0 8490.0 0.26 105760.0 -45800.0 -1.19 -0.6551 -0.5377 3557936 ACon1_000118 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)c(c4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)cc6)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F23 compound treatment 156720.0 -11100.0 -0.35 146880.0 -4670.0 -0.12 -0.33 -0.9014 3553532 ACon1_000119 CC(C)C(=O)OC1c2c(C)coc2C(=O)C3[C@@H](O)CC[C@H](C)[C@@]13C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 F24 compound treatment 147760.0 -20100.0 -0.62 94840.0 -56700.0 -1.47 -1.4824 -0.9267 3614339 ACon1_000120 O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G01 compound treatment 75560.0 -92300.0 -2.86 71400.0 -80100.0 -2.08 -3.4949 -0.9878 3559490 ACon1_000121 CC1(C)CCC[C@@]2(C)[C@H](CC/C(=C/CO)/CO)C(=CCC12)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G02 compound treatment 128880.0 -39000.0 -1.21 97760.0 -53800.0 -1.4 -1.8424 -0.9974 3060043 ACon1_000122 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G03 mock treatment 165680.0 -2190.0 -0.07 151640.0 92.5 0.0 -0.0462 -0.6816 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G04 mock treatment 167400.0 -466.0 -0.01 149960.0 -1590.0 -0.04 -0.0394 -0.9011 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G05 compound treatment 140760.0 -27100.0 -0.84 119120.0 -32400.0 -0.84 -1.1897 -1.0 3559421 ACon1_000123 C[C@H](C[C@@H]1CC=CC(=O)O1)OC(=O)CCc2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G06 compound treatment 141000.0 -26900.0 -0.83 96120.0 -55400.0 -1.44 -1.607 -0.9661 3559357 ACon1_000124 COc1cc(OC)c(C(=O)/C=C/c2ccccc2)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G07 compound treatment 88440.0 -79400.0 -2.46 91720.0 -59800.0 -1.55 -2.8394 -0.9755 3559500 ACon1_000125 C[C@@]1(CCC2C(=C1)CCC3[C@@](C)(CCCC23C)C(=O)O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G08 compound treatment 12440.0 -155000.0 -4.82 9680.0 -142000.0 -3.69 -6.0118 -0.9913 3553967 ACon1_000126 CC1CC(=O)c2c(O)c3c(O)cc(O)c(c4c(O)cc(O)c5c(O)c6C(=O)CC(C)Oc6cc45)c3cc2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G09 compound treatment 144280.0 -23600.0 -0.73 113600.0 -37900.0 -0.99 -1.214 -0.9891 3559571 ACon1_000127 COC(=O)/C=C(/CC[C@@H]1C(=C)CC[C@@H]2C(C)(C)CCC[C@@]12C)\COC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G10 compound treatment 157960.0 -9910.0 -0.31 142640.0 -8910.0 -0.23 -0.3807 -0.9903 3557671 ACon1_000128 OCCC(=O)c1ccc(O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G11 compound treatment 81360.0 -86500.0 -2.68 36920.0 -115000.0 -2.98 -4.0013 -0.9986 3559625 ACon1_000129 COC(=O)C1(C)CCCC(=C)C1CC/C(=C/CCc2ccoc2)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G12 compound treatment 177800.0 9930.0 0.31 161640.0 10100.0 0.26 0.4031 0.9968 3554892 ACon1_000130 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G13 compound treatment 166840.0 -1030.0 -0.03 154040.0 2490.0 0.06 0.0233 0.3231 3552088 ACon1_000131 C/C=C/C=C/C(=O)NCCc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G14 compound treatment 145080.0 -22800.0 -0.71 125360.0 -26200.0 -0.68 -0.9804 -0.9998 3554659 ACon1_000132 COC(=O)C1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(=C1c3ccc(O)cc3)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G15 compound treatment 147480.0 -20400.0 -0.63 111160.0 -40400.0 -1.05 -1.1887 -0.9705 3559582 ACon1_000133 CC1=CC[C@H](O)[C@@]2(C)C[C@@H](O)[C@@H]3[C@@H](OC(=O)C3=C)[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G16 compound treatment 177840.0 9970.0 0.31 140800.0 -10700.0 -0.28 0.0211 0.0506 3552120 ACon1_000134 C[C@@]1(C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12)OC(=O)/C=C/c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G17 compound treatment 153560.0 -14300.0 -0.44 144800.0 -6750.0 -0.18 -0.4374 -0.9176 926 ACon1_000135 Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G18 compound treatment 158200.0 -9670.0 -0.3 144000.0 -7550.0 -0.2 -0.3504 -0.9789 3559321 ACon1_000136 CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)C3[C@H](O)CC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)C6CC[C@]54C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G19 mock treatment 156480.0 -11400.0 -0.35 143560.0 -7990.0 -0.21 -0.3962 -0.968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G20 mock treatment 156840.0 -11000.0 -0.34 136440.0 -15100.0 -0.39 -0.5191 -0.9976 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G21 compound treatment 171800.0 3930.0 0.12 143160.0 -8390.0 -0.22 -0.0679 -0.272 3559673 ACon1_000137 CC(=O)OCC1=C[C@@H](O)[C@@H]2C=CO[C@@H](OC3OC(CO)C(O)C(O)C3O)[C@@H]21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G22 compound treatment 155440.0 -12400.0 -0.39 143760.0 -7790.0 -0.2 -0.4153 -0.9549 3557624 ACon1_000138 COc1ccc(/C=C/C(=O)O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G23 compound treatment 156600.0 -11300.0 -0.35 145120.0 -6430.0 -0.17 -0.3649 -0.943 895 ACon1_000139 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 G24 compound treatment 148800.0 -19100.0 -0.59 127440.0 -24100.0 -0.63 -0.8606 -0.9996 3551965 ACon1_000140 C/C(=C\CC[C@](C)(O)C=C)/C(=O)O[C@@H]1[C@@H]2O[C@]2(C)[C@H]3[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C[C@@]13O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H01 compound treatment 168760.0 894.0 0.03 137640.0 -13900.0 -0.36 -0.2359 -0.651 3559838 ACon1_000141 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H02 compound treatment 168280.0 414.0 0.01 145600.0 -5950.0 -0.15 -0.1002 -0.6462 3559607 ACon1_000142 COC1=CC(=O)O[C@@H](CCc2ccccc2)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H03 mock treatment 175360.0 7490.0 0.23 152920.0 1370.0 0.04 0.1894 0.8063 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H04 mock treatment 196360.0 28500.0 0.88 152000.0 453.0 0.01 0.6326 0.7165 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H05 compound treatment 151120.0 -16700.0 -0.52 130240.0 -21300.0 -0.55 -0.7584 -0.9995 1322 ACon1_000143 COc1cc2ccc(=O)oc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H06 compound treatment 159800.0 -8070.0 -0.25 135560.0 -16000.0 -0.42 -0.4705 -0.9704 3559370 ACon1_000144 COc1cc2oc(=O)ccc2cc1CC(O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H07 compound treatment 18200.0 -150000.0 -4.64 16480.0 -135000.0 -3.51 -5.7606 -0.9906 3558770 ACon1_000145 Oc1cc(cc(O)c1O)C(=O)OC[C@H]2O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](OC(=O)c4cc(O)c(O)c(O)c4)[C@@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@@H]2OC(=O)c6cc(O)c(O)c(O)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H08 compound treatment 141840.0 -26000.0 -0.81 130440.0 -21100.0 -0.55 -0.958 -0.9824 3557705 ACon1_000146 O=C(/C=C/CCc1ccc2OCOc2c1)N3CCCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H09 compound treatment 34160.0 -134000.0 -4.14 27720.0 -124000.0 -3.22 -5.2045 -0.9922 3553890 ACon1_000147 CC1(O)CC(=O)c2c(C1)ccc3C(=O)c4c(O)cccc4C(=O)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H10 compound treatment 171960.0 4090.0 0.13 142080.0 -9470.0 -0.25 -0.0843 -0.3044 3554182 ACon1_000148 CCC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H11 compound treatment 147640.0 -20200.0 -0.63 138520.0 -13000.0 -0.34 -0.6825 -0.9582 3557869 ACon1_000149 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H12 compound treatment 153640.0 -14200.0 -0.44 132400.0 -19100.0 -0.5 -0.6635 -0.9982 3555354 ACon1_000150 COc1oc2cccc(C)c2c(=O)c1C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H13 compound treatment 181320.0 13500.0 0.42 172640.0 21100.0 0.55 0.6823 0.9909 3553324 ACon1_000151 CC(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](COC(=O)C2(O)C=CCCC2=O)O[C@H]1Oc3ccccc3COC(=O)C4(O)C=CCCC4=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H14 compound treatment 75680.0 -92200.0 -2.86 70080.0 -81500.0 -2.12 -3.5165 -0.9891 3557583 ACon1_000152 CC1CCC2=C(CCCC2(C)C(=O)O)C1(C)CCc3ccoc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H15 compound treatment 162040.0 -5830.0 -0.18 146800.0 -4750.0 -0.12 -0.2149 -0.9828 3558739 ACon1_000153 COc1cc(OC)c2ccc(=O)oc2c1CC(O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H16 compound treatment 49000.0 -119000.0 -3.68 39400.0 -112000.0 -2.91 -4.6647 -0.9933 3557708 ACon1_000154 C[C@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)C4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H17 compound treatment 144480.0 -23400.0 -0.72 124800.0 -26700.0 -0.69 -1.0038 -0.9998 3557703 ACon1_000155 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H18 compound treatment 151040.0 -16800.0 -0.52 112320.0 -39200.0 -1.02 -1.0894 -0.9515 3557644 ACon1_000156 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@H](O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC[C@@]78OC[C@@]9(CCC(C)(C)CC98)[C@H](O)C[C@]76C)C4(C)C)[C@@H]3O[C@@H]%10O[C@H](CO)[C@@H](O[C@@H]%11OC[C@@H](O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H19 mock treatment 168400.0 534.0 0.02 148120.0 -3430.0 -0.09 -0.0513 -0.5661 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H20 mock treatment 174920.0 7050.0 0.22 141200.0 -10300.0 -0.27 -0.0356 -0.1027 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H21 compound treatment 166960.0 -906.0 -0.03 148720.0 -2830.0 -0.07 -0.0718 -0.913 3559541 ACon1_000157 C[C@]12C[C@H]3OC(=O)C(=C)[C@H]3C[C@H]2C(=C)[C@H](O)C[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H22 compound treatment 149960.0 -17900.0 -0.55 110960.0 -40600.0 -1.05 -1.138 -0.955 3557933 ACon1_000158 C/C=C(/C)\C(=O)OC1C(OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H23 compound treatment 184800.0 16900.0 0.52 145080.0 -6470.0 -0.17 0.2522 0.4577 3555130 ACon1_000159 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O)c(OC)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 H24 compound treatment 123400.0 -44500.0 -1.38 111720.0 -39800.0 -1.03 -1.706 -0.99 3557750 ACon1_000160 O[C@@H]1C=C(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I01 compound treatment 8160.0 -160000.0 -4.95 8520.0 -143000.0 -3.72 -6.1268 -0.99 3559527 ACon1_000161 CC1=CC[C@@H]2[C@H]1[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](CC2=C)OC(=O)/C(=C/CO)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I02 compound treatment 128960.0 -38900.0 -1.21 118000.0 -33500.0 -0.87 -1.4688 -0.9873 2120761 ACon1_000162 COc1cc(OC)c(C(=O)/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I03 compound treatment 16080.0 -152000.0 -4.7 14840.0 -137000.0 -3.55 -5.8372 -0.9904 3559509 ACon1_000163 COC(=O)CCC(=O)OC[C@]1(C)CCC[C@@]2(C)C3CC[C@@]4(C)CC3(CCC12)C=C4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I04 compound treatment 197760.0 29900.0 0.93 200520.0 49000.0 1.27 1.5547 0.9878 3557562 ACon1_000164 C/C(=C\COc1ccc2ccc(=O)oc2c1)/CC3OC(=O)C(=C3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I05 mock treatment 165000.0 -2870.0 -0.09 148240.0 -3310.0 -0.09 -0.1236 -0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I06 mock treatment 172160.0 4290.0 0.13 163640.0 12100.0 0.31 0.3162 0.9269 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I07 compound treatment 139160.0 -28700.0 -0.89 99640.0 -51900.0 -1.35 -1.5826 -0.9796 3552640 ACon1_000165 C[C@@H]1C[C@@H]2OC(=O)C(=C)[C@H]2C[C@@]3(C)[C@H]1CCC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I08 compound treatment 22640.0 -145000.0 -4.5 24000.0 -128000.0 -3.31 -5.5252 -0.9887 3557649 ACon1_000166 COc1c(O)c2c(=O)cc(oc2cc1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I09 compound treatment 42880.0 -125000.0 -3.87 42400.0 -109000.0 -2.84 -4.7437 -0.9883 1036721 ACon1_000167 Oc1c(oc2ccccc2c1=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I10 compound treatment 154960.0 -12900.0 -0.4 138040.0 -13500.0 -0.35 -0.5309 -0.9979 3555603 ACon1_000168 O[C@@H]1[C@@H](O)[C@H](Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)O[C@@H]([C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I11 compound treatment 159520.0 -8350.0 -0.26 121320.0 -30200.0 -0.79 -0.7382 -0.8928 3553943 ACon1_000169 CC1=CCC[C@@H]2[C@@](C)(CCc3ccoc3)[C@@H](CC[C@]21C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I12 compound treatment 154880.0 -13000.0 -0.4 163680.0 12100.0 0.32 -0.0616 -0.1205 3554710 ACon1_000170 COC(=O)c1cc(O)cc(OC)c1Oc2cc(C)cc(O)c2C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I13 compound treatment 185080.0 17200.0 0.53 176800.0 25300.0 0.66 0.8411 0.9947 3559593 ACon1_000171 COc1ccc(cc1)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I14 compound treatment 160800.0 -7070.0 -0.22 163360.0 11800.0 0.31 0.0622 0.165 3553879 ACon1_000172 CC1(C)O[C@H]2CC(=O)OC[C@]23C4CC[C@@]5(C)[C@@H](OC(=O)[C@H]6O[C@]65[C@]4(C)C(=O)C(=C13)O)c7ccoc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I15 compound treatment 168400.0 534.0 0.02 153680.0 2130.0 0.06 0.0509 0.8798 1032910 ACon1_000173 COc1ccc2OC(CC(=O)c2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I16 compound treatment 166280.0 -1590.0 -0.05 154560.0 3010.0 0.08 0.0206 0.2228 1362 ACon1_000174 COc1c2occc2cc3ccc(=O)oc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I17 compound treatment 141840.0 -26000.0 -0.81 129160.0 -22400.0 -0.58 -0.9815 -0.9871 1568908 ACon1_000175 COc1cccc2oc(cc(=O)c12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I18 compound treatment 161080.0 -6790.0 -0.21 148800.0 -2750.0 -0.07 -0.1992 -0.8969 1498810 ACon1_000176 CC(=CCOc1c2ccoc2cc3oc(=O)ccc13)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I19 compound treatment 173840.0 5970.0 0.19 160800.0 9250.0 0.24 0.3009 0.9917 1913676 ACon1_000177 COc1ccc(cc1)C(=O)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I20 compound treatment 182640.0 14800.0 0.46 150160.0 -1390.0 -0.04 0.2982 0.6494 3559840 ACon1_000178 COc1cc2oc(=O)ccc2c(OC)c1CC(O)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I21 mock treatment 166120.0 -1750.0 -0.05 172200.0 20700.0 0.54 0.3412 0.6326 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I22 mock treatment 172120.0 4250.0 0.13 156920.0 5370.0 0.14 0.1919 0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I23 compound treatment 169080.0 1210.0 0.04 172240.0 20700.0 0.54 0.4068 0.7547 1539 ACon1_000179 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 I24 compound treatment 137600.0 -30300.0 -0.94 118040.0 -33500.0 -0.87 -1.2787 -0.9993 3559836 ACon1_000180 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O)[C@]3(C)CO)[C@H](O)[C@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J01 compound treatment 134640.0 -33200.0 -1.03 159320.0 7770.0 0.2 -0.5852 -0.5578 3557805 ACon1_000181 CC1=CC(CC2(C)OC2COc3c4occc4cc5ccc(=O)oc35)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J02 compound treatment 163440.0 -4430.0 -0.14 154560.0 3010.0 0.08 -0.0416 -0.2636 3559624 ACon1_000182 COc1ccc(cc1)C2CC(=O)Oc3cc(O)cc(O)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J03 compound treatment 159680.0 -8190.0 -0.25 159960.0 8410.0 0.22 -0.0248 -0.0741 3559225 ACon1_000183 CC(=O)OCC(=C)[C@@H]1Cc2cc(ccc2O1)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J04 compound treatment 180360.0 12500.0 0.39 141160.0 -10400.0 -0.27 0.0829 0.1756 2060480 ACon1_000184 Oc1ccc(cc1)C2CC(=O)c3ccccc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J05 mock treatment 188440.0 20600.0 0.64 167360.0 15800.0 0.41 0.7413 0.9774 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J06 mock treatment 179920.0 12100.0 0.37 144280.0 -7270.0 -0.19 0.1306 0.312 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J07 compound treatment 167440.0 -426.0 -0.01 158760.0 7210.0 0.19 0.1232 0.6556 3559346 ACon1_000185 C[C@H]1[C@H]2[C@H](CC3C4C[C@H](OC5OC(C)C(O)C(O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)C5O)C7C[C@@H](O)CC[C@]7(C)C4CC[C@]23C)OC81OCC(C)CC8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J08 compound treatment 163200.0 -4670.0 -0.14 152760.0 1210.0 0.03 -0.08 -0.5403 3614341 ACon1_000186 COc1c2C(=O)OCc2c(C)c3OC4(C)CC5(O)OCC6(C)OC7(CCC(C)(C4Cc13)C65O7)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J09 compound treatment 155440.0 -12400.0 -0.39 150880.0 -668.0 -0.02 -0.2845 -0.7382 3554184 ACon1_000187 CCC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC3CCC(O3)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J10 compound treatment 190880.0 23000.0 0.71 167400.0 15900.0 0.41 0.7955 0.966 3557772 ACon1_000188 COc1cc(OC)c2ccc(=O)oc2c1CC(O)C(C)(C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J11 compound treatment 239560.0 71700.0 2.22 172160.0 20600.0 0.54 1.9495 0.8531 3199169 ACon1_000189 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J12 compound treatment 172840.0 4970.0 0.15 156920.0 5370.0 0.14 0.2077 0.9988 3557412 ACon1_000190 Oc1ccc(/C=C\NC=O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J13 compound treatment 17440.0 -150000.0 -4.66 16120.0 -135000.0 -3.52 -5.7839 -0.9904 3552568 ACon1_000191 C[C@@H](C1CC[C@H]2C3C[C@H]4O[C@]45[C@@H](O)C=CC(=O)[C@]5(C)C3CC[C@]12C)C6CC(=C(CO)C(=O)O6)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J14 compound treatment 202160.0 34300.0 1.06 198760.0 47200.0 1.23 1.6188 0.9974 3614342 ACon1_000192 O[C@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J15 compound treatment 71640.0 -96200.0 -2.98 54360.0 -97200.0 -2.53 -3.8938 -0.9966 3557791 ACon1_000193 CC(=CCc1c2OC(CC(=O)c2c(O)c3C=CC(C)(C)Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J16 compound treatment 138880.0 -29000.0 -0.9 148200.0 -3350.0 -0.09 -0.6966 -0.772 3557677 ACon1_000194 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O[C@@H]8OC[C@](O)(CO)[C@H]8O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J17 compound treatment 139240.0 -28600.0 -0.89 159120.0 7570.0 0.2 -0.4881 -0.5372 3558159 ACon1_000195 COc1cc(ccc1O)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J18 compound treatment 13640.0 -154000.0 -4.78 13280.0 -138000.0 -3.59 -5.9193 -0.9901 3557646 ACon1_000196 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@H](O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC[C@@]78OC[C@@]9(CCC(C)(C)CC98)[C@H](O)C[C@]76C)C4(C)C)[C@@H]3O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J19 compound treatment 176760.0 8890.0 0.28 161320.0 9770.0 0.25 0.3744 0.9992 3559382 ACon1_000197 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3ccc(O)cc3)[C@H](O)[C@@H](OC(=O)c4ccc(O)cc4)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J20 compound treatment 171360.0 3490.0 0.11 162880.0 11300.0 0.29 0.2848 0.9077 3557547 ACon1_000198 CC(OC1OC(CO)C(O)C(O)C1O)/C=C/C2(O)C(C)CC(=O)CC2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J21 mock treatment 180920.0 13100.0 0.4 172320.0 20800.0 0.54 0.6676 0.9899 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J22 mock treatment 184640.0 16800.0 0.52 162000.0 10500.0 0.27 0.5595 0.9542 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J23 compound treatment 167720.0 -146.0 0.0 158280.0 6730.0 0.17 0.1205 0.6886 3559530 ACon1_000199 C[C@H]1C[C@@H]2O[C@@]31CCC(=C3[C@H]4OC(=O)C(=C)[C@@H]24)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 J24 compound treatment 155440.0 -12400.0 -0.39 139080.0 -12500.0 -0.32 -0.5013 -0.9963 3557731 ACon1_000200 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc3occ(c4ccc(O)cc4)c(=O)c13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K01 compound treatment 122600.0 -45300.0 -1.4 172360.0 20800.0 0.54 -0.6094 -0.4054 3558170 ACon1_000201 C/C/1=C\CC\C(=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](C1)OC(=O)C(=C)C(O)CO)\CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K02 compound treatment 159040.0 -8830.0 -0.27 156720.0 5170.0 0.13 -0.0983 -0.3227 1449 ACon1_000202 CN1[C@@H](CCC1=O)c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K03 compound treatment 80320.0 -87500.0 -2.71 76440.0 -75100.0 -1.95 -3.298 -0.9869 3553119 ACon1_000203 C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2CC3=C(C)C(=O)C[C@@H]13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K04 compound treatment 162920.0 -4950.0 -0.15 168400.0 16900.0 0.44 0.2013 0.4338 3557742 ACon1_000204 CC(=CCc1cc(O)ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K05 compound treatment 126400.0 -41500.0 -1.28 112880.0 -38700.0 -1.0 -1.6189 -0.9926 3559441 ACon1_000205 COc1cc(ccc1O)c2oc3cc(O)c(OC)c(O)c3c(=O)c2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K06 compound treatment 120640.0 -47200.0 -1.46 133720.0 -17800.0 -0.46 -1.3622 -0.8875 3557579 ACon1_000206 OCC1OC(C(O)C(O)C1O)c2c(O)cc3oc(cc(=O)c3c2O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K07 mock treatment 168600.0 734.0 0.02 152640.0 1090.0 0.03 0.0361 0.9939 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K08 mock treatment 165040.0 -2830.0 -0.09 158560.0 7010.0 0.18 0.0669 0.331 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K09 compound treatment 177160.0 9290.0 0.29 168560.0 17000.0 0.44 0.5162 0.9784 1442461 ACon1_000207 COc1ccc2c(=O)cc(oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K10 compound treatment 171680.0 3810.0 0.12 170280.0 18700.0 0.49 0.4277 0.854 3554705 ACon1_000208 COC(=O)c1cc(O)cc(OC)c1C(=O)c2c(O)cc(C)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K11 compound treatment 23960.0 -144000.0 -4.46 22960.0 -129000.0 -3.34 -5.5154 -0.9899 3054523 ACon1_000209 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K12 compound treatment 188200.0 20300.0 0.63 181360.0 29800.0 0.77 0.9932 0.9947 3559363 ACon1_000210 C/C/1=C\CC\C(=C\CC\C(=C\C2OC(=O)C(=C)C2CC1)\C)\C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K13 compound treatment 172240.0 4370.0 0.14 161080.0 9530.0 0.25 0.271 0.9597 1250866 ACon1_000211 COc1ccc(cc1)C2CC(=O)c3ccccc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K14 compound treatment 166240.0 -1630.0 -0.05 170920.0 19400.0 0.5 0.3203 0.6332 3557490 ACon1_000212 CC12CCCC(CO)(CO)C2C(=O)CC3(CC4CCC31)CC4=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K15 mock treatment 188240.0 20400.0 0.63 153840.0 2290.0 0.06 0.4885 0.7704 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K16 mock treatment 167120.0 -746.0 -0.02 182080.0 30500.0 0.79 0.5446 0.6862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K17 compound treatment 161400.0 -6470.0 -0.2 163680.0 12100.0 0.32 0.0812 0.2175 3559604 ACon1_000213 Oc1ccc2C(=O)/C(=C/c3ccc(O)c(O)c3)/Oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K18 compound treatment 13080.0 -155000.0 -4.8 14040.0 -138000.0 -3.57 -5.9176 -0.9895 3557612 ACon1_000214 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)[C@H](O[C@@H]3O[C@@H](C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]3OC(=O)C)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K19 compound treatment 109440.0 -58400.0 -1.81 88000.0 -63500.0 -1.65 -2.4476 -0.9989 3559756 ACon1_000215 CC(=CCC[C@](C)(O)C1CC[C@]2(C)C1CC[C@@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]32C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K20 compound treatment 144600.0 -23300.0 -0.72 172200.0 20700.0 0.54 -0.1303 -0.145 3559323 ACon1_000216 CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)C3[C@H](O)CC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)C6CC[C@]54C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K21 compound treatment 158720.0 -9150.0 -0.28 153400.0 1850.0 0.05 -0.1664 -0.5787 1026747 ACon1_000217 OC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K22 compound treatment 214720.0 46900.0 1.45 173640.0 22100.0 0.57 1.4324 0.9176 3559843 ACon1_000218 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K23 mock treatment 169800.0 1930.0 0.06 163920.0 12400.0 0.32 0.2697 0.8247 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 K24 mock treatment 148160.0 -19700.0 -0.61 160720.0 9170.0 0.24 -0.2632 -0.4016 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L01 compound treatment 119040.0 -48800.0 -1.51 159760.0 8210.0 0.21 -0.9189 -0.6014 3526 ACon1_000219 Oc1ccc2ccc(=O)oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L02 compound treatment 26560.0 -141000.0 -4.38 23400.0 -128000.0 -3.33 -5.4503 -0.9909 3559553 ACon1_000220 C/C=C(\C)/C(=O)O[C@H]1C=C(CO)C(=O)[C@H](OC(=O)C)[C@H]1C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L03 compound treatment 30560.0 -137000.0 -4.25 17680.0 -134000.0 -3.48 -5.4678 -0.995 3558112 ACon1_000221 COc1cc(O)cc(O)c1C(=O)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L04 compound treatment 239240.0 71400.0 2.21 223560.0 72000.0 1.87 2.8868 0.9965 3559775 ACon1_000222 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@]61CC[C@@H](C)CO6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L05 compound treatment 240800.0 72900.0 2.26 198960.0 47400.0 1.23 2.469 0.9593 2137 ACon1_000223 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L06 compound treatment 135680.0 -32200.0 -1.0 141760.0 -9790.0 -0.25 -0.885 -0.8599 3559437 ACon1_000224 CC(=CC(=O)OC(C)(C)[C@H]1Oc2ccc3ccc(=O)oc3c2[C@H]1OC(=O)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L07 mock treatment 169480.0 1610.0 0.05 152800.0 1250.0 0.03 0.0584 0.9784 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L08 mock treatment 172200.0 4330.0 0.13 149360.0 -2190.0 -0.06 0.0548 0.3755 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L09 compound treatment 55040.0 -113000.0 -3.5 60680.0 -90900.0 -2.36 -4.1414 -0.9817 3559831 ACon1_000225 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L10 compound treatment 183200.0 15300.0 0.48 155320.0 3770.0 0.1 0.4053 0.8354 3558043 ACon1_000226 COc1cc(CC(CO)C(CO)Cc2ccc(O)c(OC)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L11 compound treatment 207720.0 39900.0 1.23 199800.0 48300.0 1.25 1.7597 1.0 3554965 ACon1_000227 COc1cc(O)c(C(=O)O)c(c1)c2cc(O)c(O)cc2C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L12 compound treatment 162640.0 -5230.0 -0.16 146640.0 -4910.0 -0.13 -0.2047 -0.993 3180152 ACon1_000228 CC(=C)[C@@H]1CC[C@]2(COC(=O)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)C)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L13 compound treatment 176360.0 8490.0 0.26 165480.0 13900.0 0.36 0.4421 0.9877 3551952 ACon1_000229 C/C(=C\1/CCC2(COC3C2)C1CCC3(O)C(=O)O)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L14 compound treatment 180240.0 12400.0 0.38 157600.0 6050.0 0.16 0.3823 0.9226 3557691 ACon1_000230 CC(C)C1C(OC(=O)/C=C/c2ccccc2)C3OC1CC(C)(O)C(CCC3(C)O)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L15 mock treatment 178400.0 10500.0 0.33 184120.0 32600.0 0.85 0.8292 0.9142 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L16 mock treatment 179360.0 11500.0 0.36 160560.0 9010.0 0.23 0.4174 0.9793 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L17 compound treatment 171240.0 3370.0 0.1 178960.0 27400.0 0.71 0.5776 0.8023 1029504 ACon1_000231 Oc1cc(O)c2C(=O)CC(Oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L18 compound treatment 183240.0 15400.0 0.48 210960.0 59400.0 1.54 1.4284 0.8842 3557784 ACon1_000232 O[C@H]1CO[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L19 compound treatment 176160.0 8290.0 0.26 171440.0 19900.0 0.52 0.5472 0.948 3555882 ACon1_000233 OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L20 compound treatment 170920.0 3050.0 0.09 151720.0 173.0 0.0 0.0701 0.7398 3557549 ACon1_000234 C[C@](OC(=O)/C=C/c1ccc(O)c(O)c1)([C@@H](O)CO)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L21 compound treatment 181280.0 13400.0 0.42 158640.0 7090.0 0.18 0.4242 0.933 3559569 ACon1_000235 COC(=O)/C=C(\C)/CC[C@@H]1C(=C)CC[C@@H]2C(C)(C)CCC[C@@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L22 compound treatment 88320.0 -79500.0 -2.46 78560.0 -73000.0 -1.9 -3.0838 -0.9916 3557634 ACon1_000236 C/C=C(/C)\C(=O)OC1C(OC(=O)/C(=C\C)/C)C(C)(C)Oc2ccc3ccc(=O)oc3c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L23 mock treatment 192560.0 24700.0 0.77 168880.0 17300.0 0.45 0.8595 0.9681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 L24 mock treatment 143840.0 -24000.0 -0.74 159600.0 8050.0 0.21 -0.3785 -0.4894 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M01 compound treatment 132520.0 -35300.0 -1.1 190600.0 39100.0 1.01 -0.0569 -0.0381 3559074 ACon1_000237 COc1cc(O)c2C(=O)C[C@@H](Oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M02 compound treatment 153000.0 -14900.0 -0.46 147240.0 -4310.0 -0.11 -0.4048 -0.8541 959 ACon1_000238 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M03 compound treatment 179040.0 11200.0 0.35 165560.0 14000.0 0.36 0.5023 0.9997 1002015 ACon1_000239 O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M04 compound treatment 130400.0 -37500.0 -1.16 161880.0 10300.0 0.27 -0.631 -0.5296 3557491 ACon1_000240 CC12CC3(CC2C1CC34)CCC5C(CO)(CO)CC(=O)CC45C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M05 compound treatment 128960.0 -38900.0 -1.21 140280.0 -11300.0 -0.29 -1.0594 -0.854 3559514 ACon1_000241 CC(CC[C@@]1(C)[C@H](C)CC[C@]2(C)C1CC(=O)C=C2C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M06 compound treatment 186080.0 18200.0 0.56 187720.0 36200.0 0.94 1.0636 0.9702 3558910 ACon1_000242 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@](C)(CO)C5CC[C@]43C)[C@@H]2[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M07 compound treatment 166160.0 -1710.0 -0.05 188960.0 37400.0 0.97 0.65 0.6677 3559317 ACon1_000243 C[C@@H]1CC[C@@H](/C=C(\C)/C(=O)O)C2=C(C)C[C@@H](OC(=O)C)[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M08 compound treatment 91800.0 -76100.0 -2.36 104120.0 -47400.0 -1.23 -2.5379 -0.9543 3552818 ACon1_000244 C[C@]1(CC[C@]2(C)CC[C@]3(C)C4=CC(=O)c5cc(O)c(O)cc5[C@]4(C)CC[C@@]3(C)[C@@H]2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M09 mock treatment 178160.0 10300.0 0.32 168400.0 16900.0 0.44 0.5352 0.9879 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M10 mock treatment 186840.0 19000.0 0.59 159600.0 8050.0 0.21 0.5636 0.9033 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M11 compound treatment 194080.0 26200.0 0.81 152560.0 1010.0 0.03 0.5929 0.7296 3553135 ACon1_000245 C[C@H]1CC[C@H](OC(=O)C)[C@H]2C(=O)c3occ(C)c3[C@@H](OC(=O)C)[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M12 compound treatment 196000.0 28100.0 0.87 160520.0 8970.0 0.23 0.7812 0.8658 3554653 ACon1_000246 COC(=O)C(=C)CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M13 mock treatment 170120.0 2250.0 0.07 159360.0 7810.0 0.2 0.1929 0.8987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M14 mock treatment 171080.0 3210.0 0.1 154200.0 2650.0 0.07 0.1191 0.9838 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M15 compound treatment 122680.0 -45200.0 -1.4 165000.0 13500.0 0.35 -0.7428 -0.5148 3551999 ACon1_000247 C/C=C(/C)\C(=O)O[C@@H]1C[C@@H](OC(=O)/C(=C\C)/C)[C@](C)(CO)C2C3[C@H](C)CC(=O)C2[C@@]31C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M16 compound treatment 183360.0 15500.0 0.48 199800.0 48300.0 1.25 1.226 0.9132 3552704 ACon1_000248 C[C@@H]1CC[C@H](O)/C=C/C(=O)O[C@H](C)CC[C@H](O)/C=C/C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M17 compound treatment 189840.0 22000.0 0.68 163760.0 12200.0 0.32 0.7058 0.9396 1502018 ACon1_000249 COc1ccc2oc(cc(=O)c2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M18 compound treatment 149120.0 -18700.0 -0.58 167600.0 16100.0 0.42 -0.1158 -0.1619 3557806 ACon1_000250 COC(=O)C1=CO[C@@H](OC2OC(O)C(O)C(O)C2CO)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)OC(=O)/C=C/c5ccc(OC6OC(CO)C(O)C(O)C6O)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M19 compound treatment 178720.0 10900.0 0.34 173360.0 21800.0 0.57 0.6386 0.9689 1012 ACon1_000251 Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M20 compound treatment 168840.0 974.0 0.03 187720.0 36200.0 0.94 0.6859 0.7294 3559846 ACon1_000252 OC[C@H]1O[C@@H](Oc2ccccc2/C=C/C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M21 compound treatment 174720.0 6850.0 0.21 158120.0 6570.0 0.17 0.2709 0.9942 3559747 ACon1_000253 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M22 compound treatment 170480.0 2610.0 0.08 166000.0 14500.0 0.38 0.3228 0.8403 3554833 ACon1_000254 COc1cc(C)c(C(=O)O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2OC(=O)C)n3ccc(=O)[nH]c3=O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M23 compound treatment 181560.0 13700.0 0.42 172160.0 20600.0 0.54 0.6787 0.9933 3559655 ACon1_000255 COc1cc(/C=C/C(=O)OCC[N+](C)(C)C)cc(OC)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 M24 compound treatment 120040.0 -47800.0 -1.48 131640.0 -19900.0 -0.52 -1.4136 -0.9006 3559343 ACon1_000256 COc1ccc(/C=C/C(=O)O[C@@H]2[C@@H](CO)O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@H]2O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N01 compound treatment 150960.0 -16900.0 -0.52 164920.0 13400.0 0.35 -0.1247 -0.1984 3558015 ACon1_000257 COc1c(O)cc2OC(CC(=O)c2c1O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N02 compound treatment 118560.0 -49300.0 -1.53 203240.0 51700.0 1.34 -0.1305 -0.0642 3559555 ACon1_000258 COC(=O)[C@@]1(C)CCC[C@]2(C)[C@@H](CC/C(=C/C(=O)O)/C)C(=C)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N03 compound treatment 64720.0 -103000.0 -3.2 107480.0 -44100.0 -1.14 -3.0695 -0.9042 3557706 ACon1_000259 O=C(CCCCCC/C=C/c1ccc2OCOc2c1)N3CCCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N04 compound treatment 171040.0 3170.0 0.1 189440.0 37900.0 0.98 0.7657 0.7739 1538 ACon1_000260 Oc1ccc(c(O)c1)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N05 compound treatment 156720.0 -11100.0 -0.35 198880.0 47300.0 1.23 0.6254 0.4896 3557638 ACon1_000261 COC(=O)c1ccccc1O[C@@H]2O[C@H](CO[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N06 compound treatment 191240.0 23400.0 0.72 183040.0 31500.0 0.82 1.0907 0.9981 3614343 ACon1_000262 CC(C)C(NC(=O)C)C(=O)O[C@H]1CCC(C)(C)[C@@H]2CC=C3C(=O)OCC3(O)[C@@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N07 compound treatment 153680.0 -14200.0 -0.44 164560.0 13000.0 0.34 -0.0717 -0.1294 3553729 ACon1_000263 CC(CO)CCCC(C)(O)c1ccc(cc1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N08 compound treatment 143440.0 -24400.0 -0.76 158760.0 7210.0 0.19 -0.4027 -0.5164 3614345 ACon1_000264 CC1(CCOC2OC(CO)C(O)C(O)C2O)CCC3C(=CCC4C(C)(CCCC34C)C(=O)O)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N09 mock treatment 181640.0 13800.0 0.43 164880.0 13300.0 0.35 0.5467 0.9946 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N10 mock treatment 171920.0 4050.0 0.13 148360.0 -3190.0 -0.08 0.0303 0.2011 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N11 compound treatment 193480.0 25600.0 0.79 173080.0 21500.0 0.56 0.9568 0.9854 3559351 ACon1_000265 CCCCC(CCC)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N12 compound treatment 166160.0 -1710.0 -0.05 92720.0 -58800.0 -1.53 -1.1182 -0.7311 3559523 ACon1_000266 CC(=CC(=O)O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)C3CCC2=C)C1=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N13 mock treatment 182000.0 14100.0 0.44 163600.0 12100.0 0.31 0.5311 0.9865 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N14 mock treatment 186160.0 18300.0 0.57 158840.0 7290.0 0.19 0.5348 0.8948 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N15 compound treatment 166240.0 -1630.0 -0.05 213320.0 61800.0 1.61 1.0993 0.6846 2181 ACon1_000267 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3cc(O)c(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N16 compound treatment 127640.0 -40200.0 -1.25 170280.0 18700.0 0.49 -0.5372 -0.4015 3557681 ACon1_000268 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N17 compound treatment 122800.0 -45100.0 -1.4 135120.0 -16400.0 -0.43 -1.2892 -0.8829 3557477 ACon1_000269 Oc1ccc2C(=O)CC(Oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N18 compound treatment 132520.0 -35300.0 -1.1 185240.0 33700.0 0.88 -0.1554 -0.1108 270 ACon1_000270 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N19 compound treatment 169280.0 1410.0 0.04 155440.0 3890.0 0.1 0.1025 0.9299 3558281 ACon1_000271 CC(C)C(O)CC(C)O[C@@H]1O[C@H](CO[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N20 compound treatment 97320.0 -70500.0 -2.19 107360.0 -44200.0 -1.15 -2.3575 -0.9548 3553516 ACon1_000272 CC(C)C(=O)O[C@@H]1C[C@@]2(C)O[C@](O)(C[C@@H]2O)[C@@H](C)C[C@H]3OC(=O)C(=C)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N21 compound treatment 124480.0 -43400.0 -1.34 165120.0 13600.0 0.35 -0.7012 -0.5045 3559609 ACon1_000273 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O[C@@H]5O[C@H](CO)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O[C@H]6CC[C@@]7(C)C(CC[C@]8(C)C7CC[C@@]9%10OC[C@@]%11(CCC(C)(C)CC%11%10)[C@H](O)C[C@]98C)C6(C)C)O[C@@H]3C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N22 compound treatment 140520.0 -27300.0 -0.85 135360.0 -16200.0 -0.42 -0.8965 -0.9478 3552601 ACon1_000274 C[C@@H](CC[C@H]1C(=CC(=O)C2C(C)(C)CCC[C@]12C)C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N23 compound treatment 144800.0 -23100.0 -0.71 147080.0 -4470.0 -0.12 -0.5874 -0.8113 1307633 ACon1_000275 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 N24 compound treatment 136080.0 -31800.0 -0.98 143800.0 -7750.0 -0.2 -0.8388 -0.8344 3557790 ACon1_000276 CC1CCC(=O)C2(O)CC(=O)C3C(C3(C)C)C12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O01 compound treatment 139440.0 -28400.0 -0.88 175200.0 23700.0 0.61 -0.1882 -0.1753 3559471 ACon1_000277 C[C@@]12CCCC(=C)[C@@H]2C[C@@](O)(CC1)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O02 compound treatment 35560.0 -132000.0 -4.1 39040.0 -113000.0 -2.92 -4.9658 -0.9863 3185117 ACon1_000278 CC(=O)O[C@H]1CC[C@]2(C=O)[C@H]3CC[C@]4(C)[C@H](CC[C@]4(O)[C@@H]3CC[C@]2(O)C1)C5=CC(=O)OC5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O03 compound treatment 177320.0 9450.0 0.29 176160.0 24600.0 0.64 0.6593 0.9373 2069231 ACon1_000279 CC(=CCc1cc(ccc1O)C(=O)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O04 compound treatment 167520.0 -346.0 -0.01 174640.0 23100.0 0.6 0.4167 0.6944 2091975 ACon1_000280 C/C=C/C=C/[C@H]1Cc2cc(O)cc(O)c2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O05 compound treatment 156400.0 -11500.0 -0.36 181920.0 30400.0 0.79 0.3068 0.3545 3559534 ACon1_000281 CC1C[C@@H]2OC(=O)C(=C)C2C[C@]34O[C@]4(C)CCC13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O06 compound treatment 170880.0 3010.0 0.09 200720.0 49200.0 1.28 0.9695 0.7568 3614346 ACon1_000282 O[C@@H]1C[C@](C[C@@H](O)[C@H]1O)(OC(=O)/C=C/c2ccc(O)c(O)c2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O07 compound treatment 129880.0 -38000.0 -1.18 160800.0 9250.0 0.24 -0.6623 -0.5513 3558551 ACon1_000283 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)OC8OC(CO)C(O)C(O)C8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O08 compound treatment 141880.0 -26000.0 -0.81 180520.0 29000.0 0.75 -0.037 -0.0336 1000088 ACon1_000284 OC1C(Oc2cc(O)cc(O)c2C1=O)c3cc(O)c(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O09 compound treatment 141760.0 -26100.0 -0.81 180360.0 28800.0 0.75 -0.0426 -0.0387 3559591 ACon1_000285 C[C@@]1(O)C[C@@]2(CC1CC[C@H]23)CCC4C(C)(C)[C@H](CC[C@@]34C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O10 compound treatment 157560.0 -10300.0 -0.32 188760.0 37200.0 0.97 0.4579 0.4497 3554190 ACon1_000286 CCC/C=C/C=C/C1C[C@@H](O)[C@@H](O)C(=O)[C@H]1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O11 mock treatment 192440.0 24600.0 0.76 172080.0 20500.0 0.53 0.9156 0.9849 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O12 mock treatment 163760.0 -4110.0 -0.13 162840.0 11300.0 0.29 0.1175 0.3674 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O13 compound treatment 77280.0 -90600.0 -2.81 80320.0 -71200.0 -1.85 -3.2933 -0.9796 3069775 ACon1_000287 CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O14 compound treatment 46920.0 -121000.0 -3.75 51680.0 -99900.0 -2.59 -4.4847 -0.9839 3557505 ACon1_000288 CC(C)C(O)C(=O)O[C@H]/1C\C=C(/C)\C[C@@H](OC(=O)/C(=C/CO)/CO)[C@@H]2[C@H](OC(=O)C2=C)/C=C1/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O15 compound treatment 121240.0 -46600.0 -1.44 126320.0 -25200.0 -0.66 -1.485 -0.9361 3559563 ACon1_000289 CC1=CC(=O)[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1CC[C@@](C)(O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O16 compound treatment 165000.0 -2870.0 -0.09 239400.0 87900.0 2.28 1.5513 0.6791 3559243 ACon1_000290 COc1cc(cc(OC)c1O)C2C(CO)C(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)Cc4cc(OC)c(O)c(OC)c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O17 compound treatment 43520.0 -124000.0 -3.85 16400.0 -135000.0 -3.51 -5.2074 -0.9989 3559643 ACon1_000291 OC(CCc1ccccc1)CC(=O)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O18 compound treatment 148400.0 -19500.0 -0.6 157600.0 6050.0 0.16 -0.3153 -0.5058 3559322 ACon1_000292 CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)C3[C@H](O)CC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)C6CC[C@]54C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O19 compound treatment 163760.0 -4110.0 -0.13 200760.0 49200.0 1.28 0.8142 0.6336 1071301 ACon1_000293 COc1ccc2CC(=O)c3cc4OCOc4cc3CCN(C)Cc2c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O20 compound treatment 171000.0 3130.0 0.1 170400.0 18900.0 0.49 0.415 0.8311 3557261 ACon1_000294 OC(=O)CCC(=O)Cc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O21 compound treatment 186440.0 18600.0 0.58 203120.0 51600.0 1.34 1.3545 0.9288 1010377 ACon1_000295 Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O22 compound treatment 92280.0 -75600.0 -2.34 109800.0 -41700.0 -1.08 -2.4231 -0.9388 3557778 ACon1_000296 C/C(=C\CO)/CC[C@H]1C(=C)CCC2[C@@](C)(CO)CCC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O23 compound treatment 167160.0 -706.0 -0.02 173360.0 21800.0 0.57 0.3853 0.6793 2080073 ACon1_000297 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 O24 compound treatment 154560.0 -13300.0 -0.41 189760.0 38200.0 0.99 0.4105 0.3819 3559339 ACon1_000298 COc1c(O)c2c(=O)c(coc2cc1O[C@@H]3O[C@H](CO[C@H]4OC[C@](O)(CO)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)c5ccc(O)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P01 compound treatment 102600.0 -65300.0 -2.02 79800.0 -71700.0 -1.86 -2.7481 -0.9992 3554303 ACon1_000299 CCCCCCCCCC[C@H](C(=O)O)[C@@]1(CCC(=O)O1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P02 compound treatment 119680.0 -48200.0 -1.49 111360.0 -40200.0 -1.04 -1.7941 -0.9847 3553173 ACon1_000300 CC(=C)[C@@H]1CC[C@](C)(O)[C@H](C1)OC(=O)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P03 compound treatment 97960.0 -69900.0 -2.17 141400.0 -10100.0 -0.26 -1.718 -0.7874 3557492 ACon1_000301 CC12CC3(CC2C1CC34)CCC5C(CO)(CO)CC(O)CC45C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P04 compound treatment 131400.0 -36500.0 -1.13 153240.0 1690.0 0.04 -0.7679 -0.6791 3554488 ACon1_000302 CN1CC(C=C2[C@H]1Cc3c[nH]c4cccc2c34)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C5=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P05 compound treatment 152760.0 -15100.0 -0.47 200600.0 49100.0 1.27 0.5703 0.42 3558904 ACon1_000303 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(CO)(CO)C5CC[C@]43C)C2[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P06 compound treatment 156360.0 -11500.0 -0.36 161760.0 10200.0 0.27 -0.0645 -0.1451 3614348 ACon1_000304 COc1cc(O)c2C(=O)OC(O)(CO)C(C)c2c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P07 compound treatment 75920.0 -91900.0 -2.85 89240.0 -62300.0 -1.62 -3.1592 -0.9641 3557880 ACon1_000305 COc1cc(OC)cc(/C=C/c2ccc(O)cc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P08 compound treatment 87760.0 -80100.0 -2.48 161840.0 10300.0 0.27 -1.566 -0.6273 3614349 ACon1_000306 CC(=CCC/C(=C/CC/C(=C/Cc1c(O)cc2C(=O)N(Cc2c1O)C(CCC(=O)O)C(=O)O)/C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P09 compound treatment 138040.0 -29800.0 -0.92 205800.0 54300.0 1.41 0.3433 0.2037 3559304 ACon1_000307 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](OC(=O)C)[C@H]4O)c(oc3c2)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P10 compound treatment 132240.0 -35600.0 -1.1 198680.0 47100.0 1.22 0.0854 0.0518 3559823 ACon1_000308 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](OC6OC[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P11 mock treatment 160160.0 -7710.0 -0.24 183480.0 31900.0 0.83 0.4178 0.484 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P12 mock treatment 164840.0 -3030.0 -0.09 180120.0 28600.0 0.74 0.4586 0.6129 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P13 compound treatment 117120.0 -50700.0 -1.57 189520.0 38000.0 0.99 -0.4142 -0.2231 3559341 ACon1_000309 O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3ccc(/C=C/c4cc(O)cc(O)c4)cc3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P14 compound treatment 39760.0 -128000.0 -3.97 51840.0 -99700.0 -2.59 -4.6386 -0.9786 3557710 ACon1_000310 CO[C@@H]1[C@H](O)[C@@H](O[C@H]2C[C@@H](O)[C@@]3(C)[C@H](CC[C@@H]4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)O[C@H](C)[C@@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P15 compound treatment 139360.0 -28500.0 -0.88 196000.0 44500.0 1.16 0.1922 0.1322 3559388 ACon1_000311 COc1cc2occ(c3ccc(O[C@@H]4O[C@H](CO[C@@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3)c(=O)c2c(O)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P16 compound treatment 8120.0 -160000.0 -4.95 12000.0 -140000.0 -3.63 -6.0638 -0.9883 3557667 ACon1_000312 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@@H](C[C@@H](O)[C@]5(C)C4CC[C@]23C)O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)O[C@@]81CCC(=C)CO8 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P17 compound treatment 144280.0 -23600.0 -0.73 189880.0 38300.0 1.0 0.1875 0.1518 3614351 ACon1_000313 O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H]1OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P18 compound treatment 30880.0 -137000.0 -4.24 52840.0 -98700.0 -2.56 -4.8148 -0.9709 3552822 ACon1_000314 C[C@]1(CCC[C@]2(C)[C@@H]1CC[C@]3(C[C@@H]4CC=C32)CC4=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P19 compound treatment 136680.0 -31200.0 -0.97 163880.0 12300.0 0.32 -0.4567 -0.4486 3557267 ACon1_000315 NC(=O)Cc1ccc(O)c(Cl)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P20 compound treatment 84120.0 -83700.0 -2.59 106840.0 -44700.0 -1.16 -2.6562 -0.9343 3557599 ACon1_000316 C[C@H]1CCC(CC=C1CCC(=O)C)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P21 compound treatment 45320.0 -123000.0 -3.8 39760.0 -112000.0 -2.9 -4.7387 -0.9912 3614352 ACon1_000317 COc1ccc(cc1)C(=O)O[C@H]2CC(=CCC3(C)CC[C@@](O)(C(C)C)[C@H]23)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P22 compound treatment 126160.0 -41700.0 -1.29 109400.0 -42100.0 -1.1 -1.6881 -0.9966 3557663 ACon1_000318 C[C@@H](CC[C@H]1[C@](C)(O)CCC2C(C)(C)CCC[C@]12C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P23 compound treatment 133960.0 -33900.0 -1.05 157960.0 6410.0 0.17 -0.625 -0.5876 1113986 ACon1_000319 O=c1cccc2C3CNCC(C3)Cn21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2290 P24 compound treatment 106560.0 -61300.0 -1.9 85040.0 -66500.0 -1.73 -2.5651 -0.9989 3557792 ACon1_000320 C/C=C(\C)/C(=O)O[C@H]1C[C@@H]2O[C@]2(C)[C@@H]3[C@H]4OC(=O)C(=C)[C@@H]4C[C@@H](O)[C@@]13C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A01 compound treatment 81440.0 -71400.0 -2.21 94520.0 -53300.0 -1.38 -2.5437 -0.9745 3557665 ACon1_000321 COc1cc(O)c2c(=O)c(OC)c(oc2c1)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A02 compound treatment 143000.0 -9860.0 -0.31 132320.0 -15500.0 -0.4 -0.5005 -0.9908 3558065 ACon1_000322 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A03 compound treatment 139800.0 -13100.0 -0.4 147000.0 -799.0 -0.02 -0.3009 -0.7424 3557987 ACon1_000323 COc1ccc(cc1)c2coc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(O)c3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A04 compound treatment 144240.0 -8620.0 -0.27 144160.0 -3640.0 -0.09 -0.2558 -0.9025 3558147 ACon1_000324 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8OC[C@H](O)[C@H](O)[C@H]8O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A05 compound treatment 172520.0 19700.0 0.61 205160.0 57400.0 1.49 1.4846 0.9221 3558051 ACon1_000325 COc1cc2ccc(=O)oc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A06 compound treatment 102800.0 -50100.0 -1.55 94000.0 -53800.0 -1.4 -2.0852 -0.9987 3558231 ACon1_000326 COc1cc(O)c2c(=O)c(OC)c(oc2c1)c3cc(O)c(OC)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A07 compound treatment 158720.0 5860.0 0.18 149200.0 1400.0 0.04 0.1541 0.8324 3558131 ACon1_000327 OCC1OC(Oc2cc(O)cc(/C=C/c3ccccc3)c2)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A08 compound treatment 16080.0 -137000.0 -4.24 17240.0 -131000.0 -3.39 -5.3955 -0.9939 3553198 ACon1_000328 CC(=CCc1cc(cc(CC=C(C)C)c1O)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A09 compound treatment 173800.0 20900.0 0.65 156000.0 8200.0 0.21 0.6094 0.8925 3558232 ACon1_000329 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@H](CC[C@@H]31)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A10 compound treatment 146200.0 -6660.0 -0.21 157680.0 9880.0 0.26 0.0356 0.108 3553751 ACon1_000330 CC(O)C(O)/C=C/C=C/C(=O)O[C@@H]1C=C2COC(=O)[C@]2(O)[C@@]3(C)CCCC(C)(C)C13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A11 compound treatment 161840.0 8980.0 0.28 163760.0 16000.0 0.41 0.49 0.9811 3614354 ACon1_000331 CCCCCCCC(=O)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@](O)(CC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A12 compound treatment 183320.0 30500.0 0.94 183800.0 36000.0 0.94 1.3288 1.0 3614356 ACon1_000332 COc1c(O)cc2C(O)C(C)OC(=O)c3c(O)c(OC)c(O)c(O)c3C(O)C(C)OC(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A13 mock treatment 143920.0 -8940.0 -0.28 172120.0 24300.0 0.63 0.2509 0.3637 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A14 mock treatment 175480.0 22600.0 0.7 170960.0 23200.0 0.6 0.9211 0.9971 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A15 compound treatment 159080.0 6220.0 0.19 161120.0 13300.0 0.35 0.381 0.9618 3553760 ACon1_000333 CC(O)CCCCC(C(=O)O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A16 compound treatment 117920.0 -34900.0 -1.08 133920.0 -13900.0 -0.36 -1.0205 -0.8943 3559671 ACon1_000334 CC(CCOC(=O)C)CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A17 compound treatment 77560.0 -75300.0 -2.33 84920.0 -62900.0 -1.63 -2.8051 -0.9848 3559515 ACon1_000335 COC(=O)/C=C(\C)/CCC1(C)C(C)CCC2(C)C1CC(=O)C=C2C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A18 compound treatment 118480.0 -34400.0 -1.07 110240.0 -37600.0 -0.98 -1.4433 -0.999 2082296 ACon1_000336 O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A19 compound treatment 14720.0 -138000.0 -4.28 10640.0 -137000.0 -3.56 -5.5466 -0.9959 3553961 ACon1_000337 CC1CC(=O)C2=C(C1)C(Cl)C(O)C3(O)C(O)c4c(O)cccc4C(=O)C23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A20 compound treatment 171360.0 18500.0 0.57 166040.0 18200.0 0.47 0.7404 0.9955 3557551 ACon1_000338 COc1c(OC2OC(CO)C(O)C(O)C2O)cc(O)c3C(=O)CC(Oc13)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A21 compound treatment 84160.0 -68700.0 -2.13 87480.0 -60300.0 -1.57 -2.6134 -0.9887 3557759 ACon1_000339 C[C@@H]1CC[C@]2(C)CC[C@]3(CO)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@H]1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A22 compound treatment 144320.0 -8540.0 -0.26 146080.0 -1720.0 -0.04 -0.2187 -0.8149 3557801 ACon1_000340 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](O[C@@H]3[C@@H](O)[C@H](C)O[C@@H](OC/C(=C/CC/C(=C/CC/C(=C/CCC(C)(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C=C)/C)/C)/C)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A23 compound treatment 103600.0 -49300.0 -1.53 103120.0 -44700.0 -1.16 -1.9002 -0.9909 3557890 ACon1_000341 COc1cc(cc(OC)c1OC)C(=O)OC2OC(CO)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 A24 compound treatment 80400.0 -72500.0 -2.25 86240.0 -61600.0 -1.6 -2.7186 -0.9862 3558223 ACon1_000342 COc1cc(O)cc(OC)c1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B01 compound treatment 158120.0 5260.0 0.16 132440.0 -15400.0 -0.4 -0.167 -0.3874 3559333 ACon1_000343 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)/C(=C\C)/C1CC(=O)OCC3C(C)C(CC3C(CO)CO)OC(=O)CC4\C(=C\C)\C(OC5OC(CO)C(O)C(O)C5O)OC=C4C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B02 compound treatment 157680.0 4820.0 0.15 163400.0 15600.0 0.41 0.3922 0.9079 3559681 ACon1_000344 CC(=O)OC[C@]12CCC[C@]3(C)[C@@H]2[C@@H](OC1=O)[C@H](OC(=O)C)[C@]4(C[C@H]5CC[C@H]43)CC5=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B03 compound treatment 181480.0 28600.0 0.89 167320.0 19500.0 0.51 0.9857 0.9649 3557417 ACon1_000345 C[C@H]1[C@H](O)CCC2=CC(=O)C(=C[C@]12C)C(C)(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B04 compound treatment 154240.0 1380.0 0.04 152600.0 4800.0 0.12 0.1184 0.898 3559419 ACon1_000346 COC(=O)/C=C/c1ccc(OC)c(/C=C/C(C)(C)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B05 compound treatment 148440.0 -4420.0 -0.14 154680.0 6880.0 0.18 0.0295 0.1312 3559255 ACon1_000347 COc1c(O)c2c(=O)cc(oc2cc1O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B06 compound treatment 22040.0 -131000.0 -4.05 21720.0 -126000.0 -3.28 -5.1826 -0.9944 3555950 ACon1_000348 Oc1cccc(C(=O)NCC[C@@H](CNC(=O)c2cccc(O)c2O)NC(=O)c3cccc(O)c3O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B07 compound treatment 132640.0 -20200.0 -0.63 118440.0 -29400.0 -0.76 -0.9824 -0.9952 3555286 ACon1_000349 COc1ccc2[C@H](C)[C@H]3N(CCc4cc(OC)c(OC)cc34)Cc2c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B08 compound treatment 154480.0 1620.0 0.05 123600.0 -24200.0 -0.63 -0.4091 -0.6487 715 ACon1_000350 COc1c2ccoc2c(OC)c3oc(C)cc(=O)c13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B09 compound treatment 152160.0 -702.0 -0.02 137640.0 -10200.0 -0.26 -0.202 -0.7628 3559310 ACon1_000351 COc1cc(O)c2c(=O)c(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)c(oc2c1)c5ccc(O)c(O)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B10 compound treatment 157000.0 4140.0 0.13 145680.0 -2120.0 -0.06 0.0517 0.3708 3555614 ACon1_000352 O[C@@H]1CO[C@@H](OC[C@H]2O[C@@H](Oc3cccc4cc5COC(=O)c5c(O)c34)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B11 compound treatment 114760.0 -38100.0 -1.18 114200.0 -33600.0 -0.87 -1.4521 -0.989 1352 ACon1_000353 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B12 compound treatment 164760.0 11900.0 0.37 135240.0 -12600.0 -0.33 0.0299 0.0608 3552679 ACon1_000354 C[C@@H]1CC(=O)[C@]2(COC(=O)C)[C@H](CC[C@H](OC(=O)C)[C@@]32CO3)[C@]41C[C@H](OC4=O)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B13 mock treatment 124800.0 -28100.0 -0.87 127800.0 -20000.0 -0.52 -0.9822 -0.9697 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B14 mock treatment 117880.0 -35000.0 -1.08 128960.0 -18800.0 -0.49 -1.1125 -0.9355 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B15 compound treatment 122200.0 -30700.0 -0.95 112440.0 -35400.0 -0.92 -1.3214 -0.9999 3559749 ACon1_000355 CC(C)CC(=O)O[C@@H]1C/C(=C\CC\C(=C\[C@H]2OC(=O)C(=C)C21)\C)/C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B16 compound treatment 149280.0 -3580.0 -0.11 141600.0 -6200.0 -0.16 -0.1924 -0.9835 3554812 ACon1_000356 COc1cc(/C=C/C(=O)O[C@H]2C[C@H]3[C@@H]([C@H]2C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B17 compound treatment 153280.0 418.0 0.01 142480.0 -5320.0 -0.14 -0.0886 -0.638 3559769 ACon1_000357 COc1cc(/C=C/2\Oc3cc(O)cc(O)c3C2=O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B18 compound treatment 135200.0 -17700.0 -0.55 137440.0 -10400.0 -0.27 -0.5773 -0.9466 3557998 ACon1_000358 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)/C=C/c6ccccc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B19 compound treatment 9520.0 -143000.0 -4.44 9760.0 -138000.0 -3.59 -5.6767 -0.9944 3559817 ACon1_000359 COc1c(CC=C(C)C)cc(cc1CC=C(C)C)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B20 compound treatment 37840.0 -115000.0 -3.56 33600.0 -114000.0 -2.97 -4.6182 -0.9959 3554713 ACon1_000360 COC(=O)c1cc(OC)cc(OC)c1C(=O)c2coc(/C=C/C)c(OC)c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B21 compound treatment 53360.0 -99500.0 -3.08 23520.0 -124000.0 -3.23 -4.4633 -0.9997 3553590 ACon1_000361 CC(C)C1CCC2(C)CCC(O)C(C)(O)C2C1OC(=O)/C=C/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B22 compound treatment 144200.0 -8660.0 -0.27 147480.0 -319.0 -0.01 -0.1956 -0.7286 3558127 ACon1_000362 OCC1OC(OC2OC=CC3(O)C(OC(=O)c4ccc(O)cc4)C=C(CO)C23)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B23 compound treatment 143960.0 -8900.0 -0.28 148560.0 761.0 0.02 -0.181 -0.6547 3553394 ACon1_000363 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 B24 compound treatment 29560.0 -123000.0 -3.82 28000.0 -120000.0 -3.11 -4.9025 -0.9948 3553902 ACon1_000364 CC1=C(C)C(=O)O[C@@H](C1)[C@](C)(O)C2(O)CC[C@@]3(O)[C@@H]4CC=C5CC=CC(=O)[C@]5(C)C4CC[C@]23C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C01 compound treatment 140960.0 -11900.0 -0.37 130680.0 -17100.0 -0.44 -0.5753 -0.9957 3557813 ACon1_000365 OC1COC(Oc2cc(O)c3C[C@H](O)[C@H](Oc3c2)c4ccc(O)c(O)c4)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C02 compound treatment 176440.0 23600.0 0.73 181280.0 33500.0 0.87 1.1317 0.9962 3558044 ACon1_000366 OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C03 compound treatment 156680.0 3820.0 0.12 152400.0 4600.0 0.12 0.1682 1.0 3557757 ACon1_000367 COc1cc(O)cc2occ(c3ccc(O)cc3)c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C04 compound treatment 152280.0 -582.0 -0.02 143440.0 -4360.0 -0.11 -0.0928 -0.8095 3552816 ACon1_000368 C[C@]1(C[C@H](O)[C@@H]2[C@H](OC(=O)C2=C)[C@H]1C(=C)CO)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C05 compound treatment 153440.0 578.0 0.02 166920.0 19100.0 0.5 0.364 0.7321 3558075 ACon1_000369 OC[C@H]1O[C@@H](OCCc2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1OC(=O)/C=C/c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C06 compound treatment 152960.0 98.1 0.0 157240.0 9440.0 0.25 0.1756 0.7158 3554832 ACon1_000370 COc1cc(c(OC)cc1O)c2coc3cc(O)cc(O)c3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C07 compound treatment 111400.0 -41500.0 -1.28 86720.0 -61100.0 -1.59 -2.0306 -0.9945 3558135 ACon1_000371 COc1cc2OC(CC(=O)c2c(OC)c1C)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C08 compound treatment 94760.0 -58100.0 -1.8 104960.0 -42800.0 -1.11 -2.06 -0.9733 3559269 ACon1_000372 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C09 compound treatment 146560.0 -6300.0 -0.2 121560.0 -26200.0 -0.68 -0.6201 -0.8745 703 ACon1_000373 OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C10 compound treatment 138880.0 -14000.0 -0.43 140520.0 -7280.0 -0.19 -0.4401 -0.931 3553121 ACon1_000374 C[C@H]1CC(=O)C2=C(C1)C(O)C(O)[C@]3(O)[C@@H](O)c4c(O)cccc4C(=O)[C@@H]23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C11 mock treatment 114280.0 -38600.0 -1.2 112240.0 -35600.0 -0.92 -1.4986 -0.9919 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C12 mock treatment 129520.0 -23300.0 -0.72 125520.0 -22300.0 -0.58 -0.9207 -0.9939 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C13 compound treatment 84560.0 -68300.0 -2.12 77360.0 -70400.0 -1.83 -2.7906 -0.9974 3558186 ACon1_000375 CC1=C2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3[C@H](C1)OC(=O)Cc4ccc(O)cc4)C(=CC2=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C14 compound treatment 144120.0 -8740.0 -0.27 115880.0 -31900.0 -0.83 -0.778 -0.8917 3557399 ACon1_000376 OC1C=CC(O)C23OC13C(O)C=CC42Oc5cccc6cccc(O4)c56 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C15 mock treatment 133760.0 -19100.0 -0.59 123160.0 -24600.0 -0.64 -0.8712 -0.9992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C16 mock treatment 137000.0 -15900.0 -0.49 130480.0 -17300.0 -0.45 -0.6657 -0.999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C17 compound treatment 144840.0 -8020.0 -0.25 130440.0 -17400.0 -0.45 -0.4947 -0.9606 3553202 ACon1_000377 CC(=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C(O)CC(OC(=O)C)/C(=C/COCC(O)C(O)C(O)C(O)CO)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C18 compound treatment 131040.0 -21800.0 -0.68 135920.0 -11900.0 -0.31 -0.6963 -0.9369 3557463 ACon1_000378 COc1cc(oc(=O)c1)C2C3(O)CC4OC(=O)C3(O)C(C(=O)c5ccccc5)C2(O)C4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C19 compound treatment 45560.0 -107000.0 -3.32 34640.0 -113000.0 -2.94 -4.4299 -0.9981 3558937 ACon1_000379 O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](OC(=O)c4cc(O)c(O)c(O)c4)[C@H]1OC(=O)c5cc(O)c(O)c(O)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C20 compound treatment 166520.0 13700.0 0.42 161440.0 13600.0 0.35 0.5499 0.9961 3552950 ACon1_000380 C[C@H]1[C@@H]2[C@H](OC(=O)C)C(=O)[C@@]3(C)[C@@H](CC[C@H]4/C(=C(\CCC=C(C)C)/C(=O)O)/[C@H](C[C@@]43C)OC(=O)C)[C@@]2(C)C=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C21 compound treatment 157840.0 4980.0 0.15 135760.0 -12000.0 -0.31 -0.1121 -0.3215 3557766 ACon1_000381 CC1=C2C/C=C(\C)/C(C/C=C(\C)/CC2OC1=O)OC3OC(CO)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C22 compound treatment 136840.0 -16000.0 -0.5 130320.0 -17500.0 -0.45 -0.6722 -0.999 3559361 ACon1_000382 C[C@@H]([C@H]1CCC2C3CC=C4C[C@H](C[C@H](O)[C@]4(C)C3CC[C@]12C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C6CC(=C(CO)C(=O)O6)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C23 compound treatment 132080.0 -20800.0 -0.64 129600.0 -18200.0 -0.47 -0.7897 -0.9885 3553616 ACon1_000383 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C)[C@H]3C[C@H](O)[C@](O)(COC(=O)C)[C@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 C24 compound treatment 125520.0 -27300.0 -0.85 112120.0 -35700.0 -0.93 -1.2546 -0.999 3558764 ACon1_000384 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(OC)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D01 compound treatment 140160.0 -12700.0 -0.39 118080.0 -29700.0 -0.77 -0.8243 -0.9511 3559335 ACon1_000385 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)/C(=C\C)/C1CC(=O)OCC(CO)C3CC(OC(=O)CC4\C(=C\C)\C(OC5OC(CO)C(O)C(O)C5O)OC=C4C(=O)OC)C(C)C3COC(=O)CC6\C(=C\C)\C(OC7OC(CO)C(O)C(O)C7O)OC=C6C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D02 compound treatment 12080.0 -141000.0 -4.36 11360.0 -136000.0 -3.55 -5.5912 -0.9947 3552117 ACon1_000386 C/C=C\C(=O)O[C@@H]1C[C@H]2O[C@@H]3C=C(C)C(=O)C[C@]3(C)[C@]1(C)[C@@]42CO4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D03 compound treatment 108800.0 -44100.0 -1.37 108120.0 -39700.0 -1.03 -1.6944 -0.9904 3554011 ACon1_000387 CC1CCC(=C(CC/C(=C\COC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)/C)C1(C)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D04 compound treatment 152600.0 -262.0 -0.01 164240.0 16400.0 0.43 0.2963 0.6936 3559732 ACon1_000388 CC1=C[C@H]2OC(=O)C(=C)[C@H]2C[C@@H]3[C@H]1CC[C@@]3(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D05 compound treatment 48400.0 -104000.0 -3.24 67800.0 -80000.0 -2.08 -3.7585 -0.9771 3558877 ACon1_000389 C/C/1=C\CC\C(=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](C1)OC(=O)C(=C)CO)\CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D06 compound treatment 95280.0 -57600.0 -1.78 101360.0 -46400.0 -1.21 -2.1148 -0.9819 1607 ACon1_000390 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D07 compound treatment 122680.0 -30200.0 -0.94 156680.0 8880.0 0.23 -0.4981 -0.5171 3557737 ACon1_000391 CCCCCC(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D08 compound treatment 138880.0 -14000.0 -0.43 144560.0 -3240.0 -0.08 -0.3658 -0.829 3614357 ACon1_000392 O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D09 compound treatment 121320.0 -31500.0 -0.98 133000.0 -14800.0 -0.38 -0.963 -0.9169 3559940 ACon1_000393 COc1cc(ccc1O)C2C(CO)C(CO)Cc3cc(OC)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D10 compound treatment 127880.0 -25000.0 -0.77 122280.0 -25500.0 -0.66 -1.0162 -0.997 3557859 ACon1_000394 CC1(C)Oc2ccc3ccc(=O)oc3c2[C@@H](O)[C@H]1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D11 mock treatment 121160.0 -31700.0 -0.98 129280.0 -18500.0 -0.48 -1.0348 -0.9461 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D12 mock treatment 122760.0 -30100.0 -0.93 140560.0 -7240.0 -0.19 -0.7925 -0.8329 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D13 compound treatment 140400.0 -12500.0 -0.39 150040.0 2240.0 0.06 -0.2319 -0.5937 3557863 ACon1_000395 CCC(C)C(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D14 compound treatment 146680.0 -6180.0 -0.19 138400.0 -9400.0 -0.24 -0.3081 -0.9928 3558515 ACon1_000396 C[C@H]1Oc2c(C(CC(=O)O)c3ccccc3)c4OC(C)(C)C=Cc4c(O)c2C(=O)[C@H]1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D15 mock treatment 148680.0 -4180.0 -0.13 131280.0 -16500.0 -0.43 -0.3951 -0.8813 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D16 mock treatment 137480.0 -15400.0 -0.48 130560.0 -17200.0 -0.45 -0.6537 -0.9995 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D17 compound treatment 171720.0 18900.0 0.58 140320.0 -7480.0 -0.19 0.2758 0.4478 3559665 ACon1_000397 CCC(C[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2C3=CC(=O)[C@H]4[C@H](C)[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)c5ccccc5)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D18 compound treatment 178400.0 25500.0 0.79 145240.0 -2560.0 -0.07 0.5125 0.6454 3559379 ACon1_000398 O[C@@H]1CO[C@@H](OC[C@H]2O[C@@H](OC/C=C/c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@@H](O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D19 compound treatment 168640.0 15800.0 0.49 181240.0 33400.0 0.87 0.9601 0.963 3559700 ACon1_000399 CO[C@@H]1C[C@@]2(CC=C)[C@H](C)[C@H](OC2=C(OC)C1=O)c3ccc4OCOc4c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D20 compound treatment 162240.0 9380.0 0.29 155240.0 7440.0 0.19 0.3422 0.9804 3552828 ACon1_000400 C[C@]12CC[C@H](C[C@H]2[C@H](CCC3(O)[C@@H]4C[C@@H](CC[C@@]4(C)C=CC3=O)C(=C)C(=O)O)C(=O)C=C1)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D21 compound treatment 124880.0 -28000.0 -0.87 127840.0 -20000.0 -0.52 -0.9798 -0.9698 3559727 ACon1_000401 COC(=O)CC(C)CC[C@H]1C(=CC[C@H]2C(C)(C)[C@H](O)CC[C@]12C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D22 compound treatment 89480.0 -63400.0 -1.96 85880.0 -61900.0 -1.61 -2.5263 -0.9951 3558274 ACon1_000402 C[C@@H]1C[C@@H](OC(=O)C)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCC3=CC(=O)OC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D23 compound treatment 152920.0 58.1 0.0 162040.0 14200.0 0.37 0.2629 0.7105 3553349 ACon1_000403 CC(=O)O[C@H]1CC(=C2[C@@H]3OC(=O)C(=C)[C@@H]3CC[C@@]2(C)C1)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 D24 compound treatment 150640.0 -2220.0 -0.07 162480.0 14700.0 0.38 0.2211 0.5703 3554883 ACon1_000404 COc1cc(ccc1O)c2cc(=O)c3c(O)c(OC)c(O)c(OC)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E01 mock treatment 143880.0 -8980.0 -0.28 129600.0 -18200.0 -0.47 -0.5311 -0.9681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E02 mock treatment 149640.0 -3220.0 -0.1 155600.0 7800.0 0.2 0.0727 0.3219 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E03 compound treatment 122000.0 -30900.0 -0.96 124200.0 -23600.0 -0.61 -1.1097 -0.9769 3557985 ACon1_000405 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](C)O[C@@H](OCC3OC(Oc4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)c(O)c6)C(O)C(O)C3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E04 compound treatment 144960.0 -7900.0 -0.24 145200.0 -2600.0 -0.07 -0.2209 -0.8697 3557740 ACon1_000406 COc1ccc(/C=C/C(=O)O[C@@H]2[C@@H](O)[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@H]6O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]6O)[C@@H]2OC(=O)C)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E05 compound treatment 150080.0 -2780.0 -0.09 138480.0 -9320.0 -0.24 -0.2322 -0.9033 3558077 ACon1_000407 O[C@H]1[C@H](O)[C@@H](COC(=O)/C=C/c2ccc(O)c(O)c2)O[C@@H](OCCc3ccc(O)c(O)c3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E06 compound treatment 154800.0 1940.0 0.06 142200.0 -5600.0 -0.15 -0.0604 -0.3838 3558242 ACon1_000408 COc1cc2c(=O)c(coc2cc1O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E07 compound treatment 137720.0 -15100.0 -0.47 129800.0 -18000.0 -0.47 -0.6624 -1.0 1524104 ACon1_000409 Oc1cc(O)c2C(=O)CC(Oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E08 compound treatment 111600.0 -41300.0 -1.28 112560.0 -35200.0 -0.92 -1.5514 -0.9866 2060441 ACon1_000410 OC(=O)c1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E09 mock treatment 133440.0 -19400.0 -0.6 121600.0 -26200.0 -0.68 -0.9069 -0.9981 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E10 mock treatment 142200.0 -10700.0 -0.33 124960.0 -22800.0 -0.59 -0.6532 -0.9618 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E11 compound treatment 143000.0 -9860.0 -0.31 127600.0 -20200.0 -0.52 -0.5872 -0.9669 3614358 ACon1_000411 C[C@H]1CCC[C@@H](O)CC(=O)c2c(O)cc(O)cc2CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E12 compound treatment 170120.0 17300.0 0.53 168840.0 21000.0 0.55 0.7647 0.9999 3553963 ACon1_000412 CC1CC(=O)C2=C(C1)C3OC3C4(O)C(O)c5c(O)cccc5C(=O)C24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E13 compound treatment 153160.0 298.0 0.01 129320.0 -18500.0 -0.48 -0.333 -0.6934 2565 ACon1_000413 COC1=CC(=O)OC1(O)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E14 compound treatment 111640.0 -41200.0 -1.28 111360.0 -36400.0 -0.95 -1.5726 -0.9891 3554186 ACon1_000414 CCC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC3CCC(O3)C(C)C(=O)OC(C)CC4CCC(O4)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E15 compound treatment 125240.0 -27600.0 -0.86 120760.0 -27000.0 -0.7 -1.1019 -0.9952 3614360 ACon1_000415 COC1CC(=O)C2(C3C(CC(C)C)NC2=O)C(C=C(C)C3C)/C=C(\C)/CCC(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E16 compound treatment 160840.0 7980.0 0.25 156280.0 8480.0 0.22 0.3306 0.9984 3559688 ACon1_000416 COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O)c(OC)c3)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E17 mock treatment 145000.0 -7860.0 -0.24 135680.0 -12100.0 -0.31 -0.3949 -0.992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E18 mock treatment 141000.0 -11900.0 -0.37 137720.0 -10100.0 -0.26 -0.4451 -0.9862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E19 compound treatment 188720.0 35900.0 1.11 159080.0 11300.0 0.29 0.9929 0.8641 3557588 ACon1_000417 CC(=CCc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(CC=C(C)C)c1C(O)C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E20 compound treatment 135560.0 -17300.0 -0.54 136480.0 -11300.0 -0.29 -0.587 -0.96 3557280 ACon1_000418 C[C@H]1CC/C=C(\C)/[C@@H](O)/C=C/[C@@](C)(O)\C=C\C(=O)O[C@@H]1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E21 compound treatment 159920.0 7060.0 0.22 151560.0 3760.0 0.1 0.2237 0.9341 3557796 ACon1_000419 C/C(=C\CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C=C)/CC[C@H](O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E22 compound treatment 133720.0 -19100.0 -0.59 137800.0 -10000.0 -0.26 -0.6031 -0.9314 3554684 ACon1_000420 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](C=C)[C@@H]1C[C@H]3N(CCc4cc(O)c(O)cc34)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E23 compound treatment 134280.0 -18600.0 -0.58 132120.0 -15700.0 -0.41 -0.6952 -0.9856 3557854 ACon1_000421 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 E24 compound treatment 107360.0 -45500.0 -1.41 117640.0 -30200.0 -0.78 -1.551 -0.9616 3559947 ACon1_000422 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C\c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F01 mock treatment 148600.0 -4260.0 -0.13 148720.0 921.0 0.02 -0.0764 -0.5696 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F02 mock treatment 152320.0 -542.0 -0.02 143800.0 -4000.0 -0.1 -0.0853 -0.8109 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F03 compound treatment 145320.0 -7540.0 -0.23 148080.0 281.0 0.01 -0.1601 -0.6847 3558066 ACon1_000423 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F04 compound treatment 169040.0 16200.0 0.5 182240.0 34400.0 0.89 0.9872 0.9625 3559407 ACon1_000424 CC1=C2CC([C@@H](O)CC2(C)CCC1)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F05 compound treatment 127920.0 -24900.0 -0.77 118880.0 -28900.0 -0.75 -1.0778 -0.9999 3559280 ACon1_000425 COc1cc(cc(OC)c1O)c2cc(=O)c3c(O)c(OC)c(OC)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F06 compound treatment 139200.0 -13700.0 -0.42 138920.0 -8880.0 -0.23 -0.4624 -0.9593 3555180 ACon1_000426 COc1ccc(CCc2cc(OC)cc(=O)o2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F07 compound treatment 146040.0 -6820.0 -0.21 140560.0 -7240.0 -0.19 -0.2825 -0.9983 3559863 ACon1_000427 CCC1CN2CCc3cc(OC)c(OC)cc3C2CC1CC4=NCCc5cc(OC)c(OC)cc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F08 compound treatment 46760.0 -106000.0 -3.29 46280.0 -102000.0 -2.64 -4.1898 -0.994 3553794 ACon1_000428 CC[C@H](C)/C=C(\C)/C=C/C(=O)Cc1cc(O)c(C)c(O)c1C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F09 mock treatment 134720.0 -18100.0 -0.56 121560.0 -26200.0 -0.68 -0.8796 -0.9954 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F10 mock treatment 132240.0 -20600.0 -0.64 136520.0 -11300.0 -0.29 -0.659 -0.9375 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F11 compound treatment 124760.0 -28100.0 -0.87 153600.0 5800.0 0.15 -0.5091 -0.5761 3554484 ACon1_000429 CN1C(=O)c2ccccc2NC(=O)[C@@]31O[C@@H]3c4cccc(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F12 compound treatment 146840.0 -6020.0 -0.19 127240.0 -20600.0 -0.53 -0.5097 -0.9007 3557861 ACon1_000430 CC(=CC(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F13 compound treatment 148760.0 -4100.0 -0.13 141160.0 -6640.0 -0.17 -0.2118 -0.9887 2060491 ACon1_000431 CC(C)CC(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F14 compound treatment 108040.0 -44800.0 -1.39 107680.0 -40100.0 -1.04 -1.7191 -0.99 3552813 ACon1_000432 C[C@@H]1Oc2c(C(CC(=O)O)c3ccccc3)c4OC(C)(C)C=Cc4c(O)c2C(=O)[C@H]1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F15 compound treatment 14600.0 -138000.0 -4.28 14360.0 -133000.0 -3.47 -5.4808 -0.9945 3553624 ACon1_000433 CC(C)CC(=O)O[C@H]1C(CC2O[C@]2(C)C1=O)C(=C)C(=O)/C=C/C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F16 compound treatment 139880.0 -13000.0 -0.4 138560.0 -9240.0 -0.24 -0.4542 -0.9696 3557942 ACon1_000434 CC1CCC2(C)C(CC(=O)C=C2C)C1(C)CC/C(=C\C(=O)O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F17 mock treatment 139600.0 -13300.0 -0.41 123160.0 -24600.0 -0.64 -0.7432 -0.977 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F18 mock treatment 137920.0 -14900.0 -0.46 130120.0 -17700.0 -0.46 -0.6522 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F19 compound treatment 138760.0 -14100.0 -0.44 136520.0 -11300.0 -0.29 -0.5162 -0.9811 3559629 ACon1_000435 C/C=C(/C)\C(=O)O[C@H]1C[C@@](C)(O)C(=O)[C@@H](OC(=O)/C(=C\C)/C)[C@@]2(C)CC[C@@](O)(C(C)C)[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F20 compound treatment 153200.0 338.0 0.01 133120.0 -14700.0 -0.38 -0.2623 -0.6874 3554672 ACon1_000436 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F21 compound treatment 125720.0 -27100.0 -0.84 121480.0 -26300.0 -0.68 -1.0782 -0.9947 3559533 ACon1_000437 C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2CC3=C(C)C(=O)C[C@@H]13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F22 compound treatment 132000.0 -20900.0 -0.65 143480.0 -4320.0 -0.11 -0.5364 -0.8176 3558196 ACon1_000438 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccc(O)c(O)c6)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F23 compound treatment 24600.0 -128000.0 -3.97 19280.0 -129000.0 -3.34 -5.1714 -0.9963 3559742 ACon1_000439 C/C=C(/C)\C(=O)O[C@H]1C=C(CO)C(=O)[C@H](OC(=O)\C(=C\CO)\C)[C@H]1C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 F24 compound treatment 65120.0 -87700.0 -2.72 76000.0 -71800.0 -1.87 -3.2415 -0.9831 1003829 ACon1_000440 CCCCCCC(O)CC=CCCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G01 compound treatment 111800.0 -41100.0 -1.27 106960.0 -40800.0 -1.06 -1.65 -0.9959 3557821 ACon1_000441 OC[C@@]1(O)CO[C@H](OC[C@H]2O[C@@H](OC(CCCCc3ccc(O)cc3)CCc4ccc(O)cc4)[C@H](O[C@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@@H]2O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G02 compound treatment 145280.0 -7580.0 -0.23 156160.0 8360.0 0.22 -0.0125 -0.0391 1119359 ACon1_000442 COc1cc2ccc(=O)oc2c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G03 mock treatment 143560.0 -9300.0 -0.29 141280.0 -6520.0 -0.17 -0.3236 -0.9679 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G04 mock treatment 142800.0 -10100.0 -0.31 130960.0 -16800.0 -0.44 -0.5298 -0.9862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G05 compound treatment 149840.0 -3020.0 -0.09 141760.0 -6040.0 -0.16 -0.1772 -0.9696 3557908 ACon1_000443 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G06 compound treatment 160800.0 7940.0 0.25 148680.0 881.0 0.02 0.1901 0.7696 3552802 ACon1_000444 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G07 compound treatment 146360.0 -6500.0 -0.2 126280.0 -21500.0 -0.56 -0.5378 -0.9049 3558163 ACon1_000445 CC1(C)O[C@@]2(C)CC[C@@H]1CC2OC3OC(CO)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G08 compound treatment 146120.0 -6740.0 -0.21 146000.0 -1800.0 -0.05 -0.1808 -0.8444 3614356 ACon1_000446 COc1c(O)cc2C(O)C(C)OC(=O)c3c(O)c(OC)c(O)c(O)c3C(O)C(C)OC(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G09 compound treatment 153480.0 618.0 0.02 143440.0 -4360.0 -0.11 -0.0665 -0.5793 1658516 ACon1_000447 CC(C)(O)C(O)COc1c2ccoc2cc3oc(=O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G10 compound treatment 143880.0 -8980.0 -0.28 138760.0 -9040.0 -0.23 -0.3629 -0.9964 3614362 ACon1_000448 CC(=CCC/C(=C/CCC1(C)Oc2c3CN(C(CCC(=O)O)C(=O)O)C(=O)c3cc(O)c2CC1O)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G11 compound treatment 136640.0 -16200.0 -0.5 135400.0 -12400.0 -0.32 -0.5832 -0.9769 3553707 ACon1_000449 CC(CCC1C(C)(O)C(=O)C=C2C(C)(C)CCCC12C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G12 compound treatment 120520.0 -32300.0 -1.0 97600.0 -50200.0 -1.3 -1.6309 -0.9915 3554773 ACon1_000450 COc1c(O)ccc2oc3c(OC)c4OC5(C)CCCC(O5)c4c(O)c3c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G13 compound treatment 126080.0 -26800.0 -0.83 119080.0 -28700.0 -0.75 -1.1144 -0.9986 3553974 ACon1_000451 CC1CC(=O)OC(C)C(O)/C=C/C(=O)OC(C)C(O)/C=C/C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G14 compound treatment 134440.0 -18400.0 -0.57 133440.0 -14400.0 -0.37 -0.6674 -0.9788 3555129 ACon1_000452 COc1ccc(cc1)C2(O)C(O)C(=O)Nc3ccccc32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G15 compound treatment 133560.0 -19300.0 -0.6 131160.0 -16600.0 -0.43 -0.7286 -0.9873 3557302 ACon1_000453 CC(=O)NCCc1ccc(O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G16 compound treatment 162320.0 9460.0 0.29 168440.0 20600.0 0.54 0.5865 0.9596 3559689 ACon1_000454 CO[C@H]1C[C@@H]2N3CC(O)[C@@]2(C=C1)c4cc5OCOc5cc4C3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G17 compound treatment 137120.0 -15700.0 -0.49 135000.0 -12800.0 -0.33 -0.58 -0.9826 3557386 ACon1_000455 CC1CCCC2OC2C(=O)c3c(O)cc(O)cc3CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G18 compound treatment 36320.0 -117000.0 -3.61 84920.0 -62900.0 -1.63 -3.7086 -0.9357 3553155 ACon1_000456 C[C@H]1O[C@H](C[C@@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@H]2O)c3ccc4C(=O)C5=C(C=C[C@]6(O)C[C@@](C)(O)CC(=O)[C@]56O)C(=O)c4c3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G19 mock treatment 151680.0 -1180.0 -0.04 147640.0 -159.0 0.0 -0.0288 -0.7818 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G20 mock treatment 146280.0 -6580.0 -0.2 133040.0 -14800.0 -0.38 -0.4154 -0.9563 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G21 compound treatment 156360.0 3500.0 0.11 154480.0 6680.0 0.17 0.1994 0.9743 3554304 ACon1_000457 CCCCCCCCCCC1C(=O)OC(C(=O)O)C1(O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G22 compound treatment 139440.0 -13400.0 -0.42 124760.0 -23000.0 -0.6 -0.7173 -0.9842 1059159 ACon1_000458 COC(=O)C1=COC(C)C2CN3CCC4(C3CC21)C(=O)Nc5ccccc54 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G23 compound treatment 63720.0 -89100.0 -2.76 66160.0 -81600.0 -2.12 -3.453 -0.9915 3557966 ACon1_000459 CC(=CCc1c(O)ccc2c(=O)c(coc12)c3ccc(O)cc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 G24 compound treatment 118280.0 -34600.0 -1.07 132680.0 -15100.0 -0.39 -1.0354 -0.9073 3554685 ACon1_000460 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@H](O)C[C@]3(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H01 compound treatment 132920.0 -19900.0 -0.62 108280.0 -39500.0 -1.03 -1.163 -0.9705 3559300 ACon1_000461 C[C@@H]1O[C@@H](O[C@H]2[C@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC[C@@H]6C7[C@@](C)(O)[C@@H](CC=C(C)C)O[C@@]7(O)[C@H](O)[C@]65C)C3(C)C)O[C@H](CO)[C@H](O)[C@@H]2O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H02 compound treatment 58760.0 -94100.0 -2.92 53560.0 -94200.0 -2.45 -3.7931 -0.9962 3559819 ACon1_000462 C/C=C(\C)/C(=O)O[C@@H]1C[C@@](C)(O)C(=O)C[C@@H](O)\C(=C\[C@H]2OC(=O)C(=C)[C@@H]21)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H03 mock treatment 144600.0 -8260.0 -0.26 152160.0 4360.0 0.11 -0.1009 -0.3604 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H04 mock treatment 160240.0 7380.0 0.23 152560.0 4760.0 0.12 0.2491 0.9584 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H05 compound treatment 143400.0 -9460.0 -0.29 135680.0 -12100.0 -0.31 -0.43 -0.9994 3557937 ACon1_000463 COc1ccc(cc1)c2coc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H06 compound treatment 17600.0 -135000.0 -4.19 19360.0 -128000.0 -3.34 -5.3233 -0.9936 3559369 ACon1_000464 CC(=C)C1CCC2(CCC3(C)C(CCC4C5(C)C(C=O)C(O)C(C)(C)C5CCC43C)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H07 compound treatment 139520.0 -13300.0 -0.41 127560.0 -20200.0 -0.53 -0.6642 -0.9929 3059949 ACon1_000465 CC(=O)NCCc1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H08 compound treatment 66760.0 -86100.0 -2.67 82320.0 -65500.0 -1.7 -3.0895 -0.9764 3553802 ACon1_000466 CC[C@H](C)/C=C(\C)/C=C/C1=CC2=CC(=O)[C@]3(C)OC(=O)[C@H]([C@@H]3C2=CO1)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H09 compound treatment 54000.0 -98900.0 -3.06 56040.0 -91800.0 -2.38 -3.8518 -0.9923 3553991 ACon1_000467 Cc1cc(O)c(Oc2cc(C)cc(O)c2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H10 compound treatment 145680.0 -7180.0 -0.22 117280.0 -30500.0 -0.79 -0.7181 -0.8719 3557512 ACon1_000468 COc1cc(cc(OC)c1O)C(=O)OCC2(O)COC(OCC3OC(Oc4c(OC)cc(CO)cc4OC)C(O)C(O)C3O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H11 compound treatment 139280.0 -13600.0 -0.42 118840.0 -29000.0 -0.75 -0.8296 -0.9623 3557927 ACon1_000469 CCC/C=C/1\OC(=O)C2=C1CCC(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H12 compound treatment 145840.0 -7020.0 -0.22 141600.0 -6200.0 -0.16 -0.2677 -0.989 3558562 ACon1_000470 COc1cc2ccc(=O)oc2cc1OCC=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H13 compound treatment 144280.0 -8580.0 -0.27 131840.0 -16000.0 -0.41 -0.4812 -0.9769 3554565 ACon1_000471 COC(=O)[C@]12C(=O)C(C)C(=O)[C@]2(C)C(=C[C@H]3[C@]4(C)CC[C@H](OC(=O)C)C(C)(C)[C@H]4CC[C@@]31C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H14 compound treatment 149680.0 -3180.0 -0.1 137560.0 -10200.0 -0.27 -0.2578 -0.9088 3558607 ACon1_000472 COc1c2CC(Oc2cc3oc(CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(=O)c13)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H15 compound treatment 147520.0 -5340.0 -0.17 139440.0 -8360.0 -0.22 -0.2706 -0.991 3555928 ACon1_000473 Oc1cc2O/C(=C\c3cc(O)c(O)c(O)c3)/C(=O)c2c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H16 compound treatment 153920.0 1060.0 0.03 140000.0 -7800.0 -0.2 -0.1201 -0.5851 3554273 ACon1_000474 CCCCCC[C@H](O)[C@@H]1C[C@@H](O)C2=C(O1)[C@@H](O)CCC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H17 compound treatment 110680.0 -42200.0 -1.31 103800.0 -44000.0 -1.14 -1.7325 -0.9978 3554214 ACon1_000475 CCCC#CC#CCCCCCCCCCCC(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H18 compound treatment 150520.0 -2340.0 -0.07 142320.0 -5480.0 -0.14 -0.152 -0.9511 3554824 ACon1_000476 COc1cc(=O)oc(c1C)[C@@]2(C)O[C@H]2/C(=C\C(=C\[C@@]3(C)O[C@@H](C)[C@]4(C)OC43)\C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H19 mock treatment 159600.0 6740.0 0.21 158720.0 10900.0 0.28 0.3483 0.9886 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H20 mock treatment 156960.0 4100.0 0.13 141120.0 -6680.0 -0.17 -0.0329 -0.1531 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H21 compound treatment 158960.0 6100.0 0.19 134600.0 -13200.0 -0.34 -0.1089 -0.2781 3559440 ACon1_000477 COc1c(OC)c2c(C)cccc2oc1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H22 compound treatment 11160.0 -142000.0 -4.39 11080.0 -137000.0 -3.55 -5.6165 -0.9945 3553645 ACon1_000478 CC(C)CC1NC(=O)C23C1C(C)C(=CC3/C=C(\C)/CCC(O)C(O)/C=C/C2=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H23 compound treatment 56840.0 -96000.0 -2.98 63200.0 -84600.0 -2.2 -3.6581 -0.9889 3553179 ACon1_000479 CC(=C)C(=O)O[C@H]1CC(=C)C2C[C@H](O)[C@](O)(CO)C2[C@H]3OC(=O)C(=C)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 H24 compound treatment 92520.0 -60300.0 -1.87 112440.0 -35400.0 -0.92 -1.9717 -0.9465 3558419 ACon1_000480 CC(=O)O[C@H]1C(=C)C2C[C@]31CCC4[C@@](C)(CCC[C@@]4(C)C3CC2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I01 compound treatment 94720.0 -58100.0 -1.8 104560.0 -43200.0 -1.12 -2.0683 -0.9742 3557823 ACon1_000481 OC[C@H]1O[C@@H](OC(CCCCc2ccc(O)cc2)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I02 compound treatment 118840.0 -34000.0 -1.05 99400.0 -48400.0 -1.26 -1.6346 -0.9962 3558086 ACon1_000482 CC1(C)OC2(C)CCC1CC2OC3OC(COC(=O)c4cc(O)c(O)c(O)c4)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I03 compound treatment 134560.0 -18300.0 -0.57 133960.0 -13800.0 -0.36 -0.6552 -0.9758 3557594 ACon1_000483 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](C)O[C@@H](OC[C@H]3O[C@@H](Oc4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)cc6)[C@H](O)[C@@H](O)[C@H]3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I04 compound treatment 15760.0 -137000.0 -4.25 13520.0 -134000.0 -3.49 -5.4709 -0.9952 3554871 ACon1_000484 COc1cc(cc2OCOc21)[C@H](OC(=O)/C(=C\C)/C)[C@@H](C)OC(=O)[C@](C)(O)[C@H](C)OC(=O)/C(=C\C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I05 mock treatment 151920.0 -942.0 -0.03 145480.0 -2320.0 -0.06 -0.0632 -0.9446 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I06 mock treatment 152240.0 -622.0 -0.02 144760.0 -3040.0 -0.08 -0.0695 -0.8546 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I07 compound treatment 56600.0 -96300.0 -2.98 62520.0 -85300.0 -2.22 -3.6758 -0.9893 3554216 ACon1_000485 CCCC(=O)O[C@@H]1C[C@@](C)(OC(=O)C)C2C[C@H](OC(=O)/C(=C/C)/C)C(=C2[C@H]3OC(=O)[C@](C)(O)[C@@]31O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I08 compound treatment 149680.0 -3180.0 -0.1 142600.0 -5200.0 -0.14 -0.1652 -0.988 3558194 ACon1_000486 CC(=O)O[C@@]1(C)C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I09 compound treatment 147200.0 -5660.0 -0.18 150800.0 3000.0 0.08 -0.0689 -0.3589 3553540 ACon1_000487 CC(C)C(NC=O)C(=O)OCC(O)C(O)C(O)C(O)COC(=O)C(NC=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I10 compound treatment 172280.0 19400.0 0.6 150040.0 2240.0 0.06 0.4666 0.7719 3552799 ACon1_000488 C[C@@H]1O[C@@H](OC(=O)Cc2ccccc2)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I11 compound treatment 143040.0 -9820.0 -0.3 146920.0 -879.0 -0.02 -0.2313 -0.758 3553147 ACon1_000489 C[C@H]1CCC[C@H]2C[C@@]3(O)OC(=O)C(=C3C[C@]12C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I12 compound treatment 182320.0 29500.0 0.91 176960.0 29200.0 0.76 1.1812 0.9957 3554781 ACon1_000490 COc1c2C(=O)OCc2c(C)c3OC4(C)CC(O)C(C(C)(C)O)C(C)(CCC(=O)O)C4Cc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I13 compound treatment 137520.0 -15300.0 -0.48 140080.0 -7720.0 -0.2 -0.4779 -0.9264 3559698 ACon1_000491 C[C@H]1C[C@@]2(O)[C@H]([C@H]1O)[C@@H](O)C(=C)[C@H](O)C[C@H]3[C@@H](/C=C(\C)/C2=O)C3(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I14 compound treatment 153640.0 778.0 0.02 155240.0 7440.0 0.19 0.1538 0.7892 3614364 ACon1_000492 CC1OC(=O)C23C(=C)C4(C)OC(=O)C31OC4C5=C(CO)C6(CCC52C)C(O)CC(=O)OC6(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I15 compound treatment 164160.0 11300.0 0.35 147680.0 -119.0 0.0 0.2454 0.7008 3553199 ACon1_000493 CC(=CCc1ccc(Oc2c(O)cc(C)cc2CO)c(C(=O)O)c1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I16 compound treatment 163760.0 10900.0 0.34 143840.0 -3960.0 -0.1 0.166 0.4704 3185114 ACon1_000494 CC[C@]1(C=CCN2CC[C@]3([C@H]4N(C)c5cc(OC)ccc53)[C@@H]21)[C@@H](OC(=O)C)[C@]4(O)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I17 compound treatment 169800.0 16900.0 0.52 162360.0 14600.0 0.38 0.6386 0.9871 3559677 ACon1_000495 C/C(=C\C(=O)O)/CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I18 compound treatment 141040.0 -11800.0 -0.37 125760.0 -22000.0 -0.57 -0.6639 -0.9767 804 ACon1_000496 COc1c(C)c2COC(=O)c2c(O)c1C/C=C(\C)/CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I19 compound treatment 165360.0 12500.0 0.39 148320.0 521.0 0.01 0.2834 0.7314 3557626 ACon1_000497 COc1ccc(CCC(=O)O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I20 compound treatment 15480.0 -137000.0 -4.26 13920.0 -134000.0 -3.48 -5.4696 -0.995 3557415 ACon1_000498 COC(=O)C[C@@H]1C[C@@H](C)C2C([C@@H]1O)C(=O)c3c(O)c4C5CC(O)C(O)(C(C)O5)c4c(O)c3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I21 mock treatment 197800.0 44900.0 1.39 182520.0 34700.0 0.9 1.6225 0.9779 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I22 mock treatment 178040.0 25200.0 0.78 169240.0 21400.0 0.56 0.9456 0.9864 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I23 compound treatment 180760.0 27900.0 0.86 177680.0 29900.0 0.78 1.1602 0.9986 3557848 ACon1_000499 O[C@@H]1[C@@H](O)[C@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)O[C@@H]([C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 I24 compound treatment 111880.0 -41000.0 -1.27 136760.0 -11000.0 -0.29 -1.1007 -0.8455 3557958 ACon1_000500 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C1CCC3(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J01 compound treatment 55280.0 -97600.0 -3.02 53760.0 -94000.0 -2.44 -3.8657 -0.9944 3554282 ACon1_000501 CCCCCCC(O)CCCCCC/C=C/[C@H](OC(=O)C)[C@@H](O)[C@H](O)[C@H](N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J02 compound treatment 148240.0 -4620.0 -0.14 140200.0 -7600.0 -0.2 -0.2409 -0.9876 831700 ACon1_000502 CC(O)(CC(=O)O)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J03 compound treatment 127200.0 -25700.0 -0.8 131600.0 -16200.0 -0.42 -0.8598 -0.9558 3559146 ACon1_000503 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J04 compound treatment 180840.0 28000.0 0.87 169320.0 21500.0 0.56 1.0084 0.9775 3559332 ACon1_000504 CC1C2CCC3(C)C(O)CC=C(C)C3C2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J05 mock treatment 163400.0 10500.0 0.33 165760.0 18000.0 0.47 0.5609 0.9847 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J06 mock treatment 161080.0 8220.0 0.25 155960.0 8160.0 0.21 0.33 0.9959 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J07 compound treatment 138760.0 -14100.0 -0.44 141280.0 -6520.0 -0.17 -0.4287 -0.9149 3559937 ACon1_000505 C[C@H]1O[C@@H](OC[C@H]2O[C@@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CCC6=C5CC[C@]7(CCC(C)(C)C[C@@H]67)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C3(C)C)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J08 compound treatment 125200.0 -27700.0 -0.86 130920.0 -16900.0 -0.44 -0.9162 -0.9516 3558531 ACon1_000506 O[C@H]1[C@@H](C[C@](C[C@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)(OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O)OC(=O)/C=C/c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J09 compound treatment 176560.0 23700.0 0.73 157440.0 9640.0 0.25 0.6963 0.8975 2060122 ACon1_000507 CC1(C)Oc2cc3oc(=O)ccc3cc2C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J10 compound treatment 165680.0 12800.0 0.4 152880.0 5080.0 0.13 0.3742 0.8941 3558561 ACon1_000508 COc1cc2ccc(=O)oc2cc1OCC3OC3(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J11 compound treatment 119560.0 -33300.0 -1.03 117760.0 -30000.0 -0.78 -1.2815 -0.9905 3552721 ACon1_000509 C[C@@H]1CCC2C(C)(C)[C@H](O)CC[C@]2(C)[C@]31Cc4c(O3)c5CNC(=O)c5cc4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J12 compound treatment 180640.0 27800.0 0.86 183440.0 35600.0 0.93 1.2634 0.9993 3555910 ACon1_000510 OC[C@H]1O[C@@H](Oc2cccc3cc4COC(=O)c4c(O)c23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J13 compound treatment 95720.0 -57100.0 -1.77 101400.0 -46400.0 -1.21 -2.1044 -0.9825 154 ACon1_000511 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J14 compound treatment 165320.0 12500.0 0.39 157120.0 9320.0 0.24 0.4442 0.9748 3554559 ACon1_000512 COC(=O)[C@]1(C)OC(=O)[C@@H]2[C@](C)(C(=C)C[C@]3(O)[C@@]4(C)CCC(=O)C(C)(C)C4=C(O)C(=O)[C@@]23C)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J15 compound treatment 176800.0 23900.0 0.74 156680.0 8880.0 0.23 0.6876 0.8852 1038770 ACon1_000513 COc1cc(O)c2c(=O)c(OC)c(oc2c1)c3ccc(OC)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J16 compound treatment 163640.0 10800.0 0.33 162800.0 15000.0 0.39 0.5118 0.997 3558004 ACon1_000514 OC[C@H]1O[C@@H](O[C@@H]2OC=C([C@H]3CC=C(COC(=O)/C=C/c4ccccc4)[C@H]32)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J17 compound treatment 75640.0 -77200.0 -2.39 77520.0 -70300.0 -1.83 -2.9831 -0.9911 3552617 ACon1_000515 C[C@@H]1[C@@H](C[C@]23COC(=O)C3=CCC[C@@H]2[C@@]1(C)CC(OC(=O)C)c4ccoc4)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J18 compound treatment 144680.0 -8180.0 -0.25 131000.0 -16800.0 -0.44 -0.4879 -0.9666 1062454 ACon1_000516 COc1c(O)cc2oc(cc(=O)c2c1O)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J19 compound treatment 172400.0 19500.0 0.61 175520.0 27700.0 0.72 0.9374 0.9963 3559776 ACon1_000517 CCOC(=O)C1C(=O)C(=O)Nc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J20 compound treatment 62360.0 -90500.0 -2.8 67840.0 -80000.0 -2.08 -3.4519 -0.9891 3554280 ACon1_000518 CCCCCCC(C)C/C(=C\C(CO)\C=C(/C)\C=C\C(O)C(C)(C)c1cc(O)c([C@H]2O[C@@H](CO)C[C@@H](O)[C@@H]2O)c(=O)o1)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J21 mock treatment 159280.0 6420.0 0.2 161000.0 13200.0 0.34 0.3832 0.9664 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J22 mock treatment 160800.0 7940.0 0.25 183400.0 35600.0 0.93 0.828 0.8651 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J23 compound treatment 174320.0 21500.0 0.66 165080.0 17300.0 0.45 0.7876 0.9817 3554751 ACon1_000519 COC1=CC(=O)O[C@@H](CCc2ccccc2)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 J24 compound treatment 113040.0 -39800.0 -1.23 159720.0 11900.0 0.31 -0.6534 -0.5137 3558337 ACon1_000520 O[C@@H]1C=C(C[C@@H](O[C@@H]2O[C@H](COC(=O)/C=C/c3ccccc3)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K01 compound treatment 106080.0 -46800.0 -1.45 100600.0 -47200.0 -1.23 -1.8921 -0.9965 3557834 ACon1_000521 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]4OC[C@](O)(CO)[C@H]4O)[C@H]2OC(=O)/C=C/c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K02 compound treatment 107640.0 -45200.0 -1.4 102800.0 -45000.0 -1.17 -1.8175 -0.996 3558087 ACon1_000522 OCC1OC(Oc2cc(O)c(C(=O)O)c(/C=C/c3ccccc3)c2)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K03 compound treatment 153440.0 578.0 0.02 152720.0 4920.0 0.13 0.1031 0.7984 3558017 ACon1_000523 COc1cc(O)c2c(=O)c(OC3OC(CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H]4O)C(O)C(O)C3O)c(oc2c1)c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K04 compound treatment 11200.0 -142000.0 -4.39 11400.0 -136000.0 -3.54 -5.6097 -0.9944 3554289 ACon1_000524 CCCCCCCC(=O)O[C@H]1[C@H](OC(=O)/C(=C/C)/C)C(=C2[C@H]3OC(=O)[C@](C)(O)[C@]3(O)[C@@H](C[C@@](C)(OC(=O)C)[C@H]12)OC(=O)C(C)CC)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K05 compound treatment 188160.0 35300.0 1.09 157080.0 9280.0 0.24 0.9439 0.8428 3558061 ACon1_000525 CC1CC(O)C2C(OC(=O)C2=C)C3=C(C)C(=O)CC13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K06 compound treatment 168920.0 16100.0 0.5 158280.0 10500.0 0.27 0.5444 0.9598 3555625 ACon1_000526 O[C@H]1[C@H](O)[C@@H](COC(=O)c2ccccc2)O[C@@H](Oc3ccc(O)cc3COC(=O)C4(O)C=CCCC4=O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K07 mock treatment 162640.0 9780.0 0.3 147880.0 81.3 0.0 0.2157 0.712 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K08 mock treatment 162880.0 10000.0 0.31 151520.0 3720.0 0.1 0.2879 0.8854 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K09 compound treatment 179320.0 26500.0 0.82 177480.0 29700.0 0.77 1.125 0.9995 3559841 ACon1_000527 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@H](COC(=O)C)[C@@H](O)[C@@H](O)[C@H]5O)c(O)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K10 compound treatment 161680.0 8820.0 0.27 157040.0 9240.0 0.24 0.363 0.9979 3554769 ACon1_000528 COc1c(O)cc2C(O)C(C)OC(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K11 compound treatment 181680.0 28800.0 0.89 197240.0 49400.0 1.28 1.5398 0.9842 3557888 ACon1_000529 OC[C@H]1O[C@@H](OC(C#N)c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K12 compound treatment 165720.0 12900.0 0.4 156720.0 8920.0 0.23 0.4456 0.9668 3614365 ACon1_000530 CC1(CO)CCCC2(C)C1C(=O)CC3=C2COC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K13 compound treatment 159040.0 6180.0 0.19 165960.0 18200.0 0.47 0.469 0.9211 3559595 ACon1_000531 C/C/1=C\CC[C@@]2(C)O[C@@H]2C[C@H]3[C@H](C1)OC(=O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K14 compound treatment 170120.0 17300.0 0.53 163360.0 15600.0 0.4 0.664 0.9905 3557305 ACon1_000532 COc1cc(O)cc(C(=O)O)c1Oc2cc(C)cc(O)c2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K15 mock treatment 197840.0 45000.0 1.39 170200.0 22400.0 0.58 1.397 0.925 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K16 mock treatment 165680.0 12800.0 0.4 161560.0 13800.0 0.36 0.5337 0.9986 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K17 compound treatment 174800.0 21900.0 0.68 167000.0 19200.0 0.5 0.8334 0.9884 3614366 ACon1_000533 CC(C)CC1NC(=O)C(C)NC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K18 compound treatment 174360.0 21500.0 0.67 164440.0 16600.0 0.43 0.7768 0.9781 3559135 ACon1_000534 O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K19 compound treatment 157760.0 4900.0 0.15 155240.0 7440.0 0.19 0.244 0.9928 3557598 ACon1_000535 COc1c(O)cc2oc(c(OC)c(=O)c2c1O)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K20 compound treatment 175240.0 22400.0 0.69 173720.0 25900.0 0.67 0.9665 0.9999 3558949 ACon1_000536 C[C@@H]1O[C@@H](O[C@@H]2CO[C@@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@]3(C)CO)[C@H](O)[C@H]2O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K21 compound treatment 176160.0 23300.0 0.72 166760.0 19000.0 0.49 0.8588 0.9827 3552947 ACon1_000537 C[C@H]1[C@@H](O)C[C@H]2[C@@H]1[C@H](OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K22 compound treatment 147560.0 -5300.0 -0.16 150680.0 2880.0 0.07 -0.0632 -0.3502 1092498 ACon1_000538 OCC(O)c1nc(CO)cc2c3ccccc3[nH]c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K23 mock treatment 160480.0 7620.0 0.24 169160.0 21400.0 0.56 0.5594 0.9274 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 K24 mock treatment 121480.0 -31400.0 -0.97 145080.0 -2720.0 -0.07 -0.7375 -0.7565 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L01 compound treatment 124880.0 -28000.0 -0.87 111840.0 -36000.0 -0.93 -1.2737 -0.9993 3554760 ACon1_000539 COc1c(CO)c(O)cc2C(O)CCC(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L02 compound treatment 152480.0 -382.0 -0.01 155440.0 7640.0 0.2 0.132 0.6638 3559718 ACon1_000540 C[C@H]1C[C@H](O)C[C@H]2[C@H](OC(=O)C=C(C)C)[C@H](O)[C@H](C[C@]12C)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L03 compound treatment 38080.0 -115000.0 -3.56 45080.0 -103000.0 -2.67 -4.402 -0.99 3558002 ACon1_000541 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)/C=C/c7ccccc7)[C@H]1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L04 compound treatment 106080.0 -46800.0 -1.45 118120.0 -29700.0 -0.77 -1.5702 -0.9564 3559482 ACon1_000542 C/C=C(\C)/C(=O)O[C@@H]1C\C(=C\CC\C(=C\[C@H]2OC(=O)C(=C)C21)\C)\C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L05 compound treatment 151440.0 -1420.0 -0.04 146080.0 -1720.0 -0.04 -0.0627 -1.0 592 ACon1_000543 Oc1ccc(cc1)c2coc3cc(O)ccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L06 compound treatment 170640.0 17800.0 0.55 181440.0 33600.0 0.87 1.0076 0.9752 3614367 ACon1_000544 C[C@H]1[C@H](O)CCC2=CC(=O)[C@H](C[C@]12C)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L07 mock treatment 160480.0 7620.0 0.24 150840.0 3040.0 0.08 0.2228 0.895 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L08 mock treatment 181960.0 29100.0 0.9 162360.0 14600.0 0.38 0.905 0.9256 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L09 compound treatment 138120.0 -14700.0 -0.46 145600.0 -2200.0 -0.06 -0.3634 -0.7894 1024930 ACon1_000545 COc1c2C=CC(C)(C)Oc2cc3oc(=O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L10 compound treatment 163200.0 10300.0 0.32 174280.0 26500.0 0.69 0.713 0.9395 3558539 ACon1_000546 OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC[C@@]3(O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L11 compound treatment 129240.0 -23600.0 -0.73 119000.0 -28800.0 -0.75 -1.0466 -0.9999 3557749 ACon1_000547 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)OCC(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L12 compound treatment 167080.0 14200.0 0.44 161640.0 13800.0 0.36 0.5658 0.9949 3555408 ACon1_000548 CSC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]1[C@H]23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L13 compound treatment 174160.0 21300.0 0.66 152200.0 4400.0 0.11 0.5475 0.8175 1010501 ACon1_000549 Cn1c(=O)n(C)c2c(=O)n(C)c(=O)n(C)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L14 compound treatment 192600.0 39700.0 1.23 208800.0 61000.0 1.58 1.9914 0.9922 3558008 ACon1_000550 COc1cc(/C=C/C(=O)O[C@@H]2C[C@](O)(C[C@@H](O)[C@@H]2O)C(=O)O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L15 mock treatment 167560.0 14700.0 0.46 155000.0 7200.0 0.19 0.4543 0.9228 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L16 mock treatment 162960.0 10100.0 0.31 160880.0 13100.0 0.34 0.4616 0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L17 compound treatment 156280.0 3420.0 0.11 159600.0 11800.0 0.31 0.2917 0.8992 2060138 ACon1_000551 C[C@]1([C@H]2[C@H](C(=O)O)[C@]3(CC(=C)[C@@]4(O)C3)[C@@H](CC4)[C@]52OC1=O)[C@@H](O)C=C5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L18 compound treatment 170640.0 17800.0 0.55 168280.0 20500.0 0.53 0.7658 0.9999 3558019 ACon1_000552 CC1C2CC3C(CCC(=O)C)C3(C)CC2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L19 compound treatment 43600.0 -109000.0 -3.39 35040.0 -113000.0 -2.93 -4.4655 -0.9974 3559721 ACon1_000553 C/C(=C\CO)/C(=O)O[C@@H]1C\C(=C\CC[C@@]2(C)OC2[C@H]3OC(=O)C(=C)C31)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L20 compound treatment 107200.0 -45700.0 -1.41 114720.0 -33100.0 -0.86 -1.6082 -0.9715 3558114 ACon1_000554 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(COC(=O)/C=C/c5ccccc5)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L21 compound treatment 87760.0 -65100.0 -2.02 60880.0 -86900.0 -2.26 -3.0233 -0.9984 3553337 ACon1_000555 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@]2(C)[C@@H](CC3[C@H](OC(=O)C3=C)[C@H]2C1=C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L22 compound treatment 171760.0 18900.0 0.59 165160.0 17400.0 0.45 0.733 0.9917 3558119 ACon1_000556 COc1ccc(/C=C/C(=O)OC2CC(C)(O)C3C(OC4OC(CO)C(O)C(O)C4O)OC=CC23O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L23 mock treatment 185600.0 32700.0 1.01 159880.0 12100.0 0.31 0.9392 0.8845 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 L24 mock treatment 122520.0 -30300.0 -0.94 126360.0 -21400.0 -0.56 -1.0587 -0.9688 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M01 compound treatment 103320.0 -49500.0 -1.54 83840.0 -64000.0 -1.66 -2.2605 -0.9992 3557875 ACon1_000557 CC(CCc1ccc(O)cc1)O[C@@H]2O[C@H](CO[C@H]3OC[C@](O)(CO)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M02 compound treatment 91120.0 -61700.0 -1.91 90160.0 -57600.0 -1.5 -2.4117 -0.9927 3558144 ACon1_000558 Cc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M03 compound treatment 155760.0 2900.0 0.09 153920.0 6120.0 0.16 0.176 0.9634 3557783 ACon1_000559 O[C@H]1CO[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M04 compound treatment 190920.0 38100.0 1.18 160360.0 12600.0 0.33 1.0646 0.8701 353 ACon1_000560 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M05 compound treatment 124680.0 -28200.0 -0.87 126640.0 -21200.0 -0.55 -1.0062 -0.9751 3555963 ACon1_000561 OCC1OC(OC(=O)c2c(O)cc(O)cc2/C=C/c3ccccc3)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M06 compound treatment 35160.0 -118000.0 -3.65 40000.0 -108000.0 -2.8 -4.5593 -0.9915 3557538 ACon1_000562 CC1CC2OC(=O)C(=C)C2CC3OC31/C=C/C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M07 compound treatment 12000.0 -141000.0 -4.36 11280.0 -137000.0 -3.55 -5.5944 -0.9947 3558167 ACon1_000563 CCCCCC(=O)OC1C(OC(=O)/C(=C/C)/C)C(=C2C3OC(=O)C(C)(O)C3(O)C(CC(C)(OC(=O)C)C12)OC(=O)CCC)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M08 compound treatment 155480.0 2620.0 0.08 157400.0 9600.0 0.25 0.2338 0.8911 3558079 ACon1_000564 CC(=O)O[C@@]1(C)C[C@@H](O)[C@@H]2C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M09 mock treatment 167400.0 14500.0 0.45 163640.0 15800.0 0.41 0.6096 0.999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M10 mock treatment 164760.0 11900.0 0.37 167280.0 19500.0 0.51 0.6186 0.9879 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M11 compound treatment 173200.0 20300.0 0.63 175320.0 27500.0 0.72 0.9512 0.998 3558160 ACon1_000565 COc1cc(O)c2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M12 compound treatment 172800.0 19900.0 0.62 94240.0 -53600.0 -1.39 -0.5472 -0.3594 3614369 ACon1_000566 COc1ccc(C(=O)Oc2ccc(C)c3CC(C)OC(=O)c23)c4CC(C)OC(=O)c14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M13 mock treatment 169280.0 16400.0 0.51 155160.0 7360.0 0.19 0.495 0.9107 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M14 mock treatment 165080.0 12200.0 0.38 156040.0 8240.0 0.21 0.4191 0.9636 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M15 compound treatment 142320.0 -10500.0 -0.33 127480.0 -20300.0 -0.53 -0.6043 -0.9734 3554270 ACon1_000567 CCCCCC(O)CC(O)CC(=O)OC(CCCCC)CC(O)CC(=O)OCC(O)C(O)C(O)C(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M16 compound treatment 11920.0 -141000.0 -4.37 11200.0 -137000.0 -3.55 -5.5976 -0.9947 3559697 ACon1_000568 CC1(C)[C@H](O)CC[C@@]2(C)[C@H](COc3ccc4ccc(=O)oc4c3)C(=C)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M17 compound treatment 101520.0 -51300.0 -1.59 95480.0 -52300.0 -1.36 -2.0861 -0.9969 3614370 ACon1_000569 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@@H]3[C@@H](O)[C@H](O)[C@H](O[C@H]3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)C[C@@H](O)[C@]8(C)CC[C@]76C)[C@@]4(C)CO)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M18 compound treatment 148560.0 -4300.0 -0.13 157280.0 9480.0 0.25 0.0799 0.2854 3554688 ACon1_000570 COC(=O)C1=CO[C@@H](OC2OC(CO)C(O)C(O)C2O)[C@H](C=C)[C@@H]1CCOC(=O)c3cc(O)c(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M19 compound treatment 143760.0 -9100.0 -0.28 177120.0 29300.0 0.76 0.3393 0.4177 3553705 ACon1_000571 CC(CCC1(O)OC(=O)C=C1C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M20 compound treatment 170440.0 17600.0 0.54 154560.0 6760.0 0.18 0.5093 0.89 3559384 ACon1_000572 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@H](C[C@@H]31)OC(=O)C4=CO[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H]6[C@@H](C)[C@@H](O)C[C@@H]64 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M21 compound treatment 175160.0 22300.0 0.69 165240.0 17400.0 0.45 0.809 0.9791 3557814 ACon1_000573 COc1cc(cc(OC)c1O)C2C(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(CO)Cc4cc(OC)c(O)c(OC)c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M22 compound treatment 101720.0 -51100.0 -1.58 118520.0 -29300.0 -0.76 -1.6584 -0.9435 1023017 ACon1_000574 COc1cc2oc(=O)ccc2cc1CC=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M23 compound treatment 166440.0 13600.0 0.42 159720.0 11900.0 0.31 0.5165 0.9887 3558029 ACon1_000575 COc1ccc(CCO[C@@H]2O[C@H](CO[C@@H]3OC[C@H](O)[C@H](O)[C@H]3O)[C@@H](OC(=O)/C=C/c4ccc(O)c(OC)c4)[C@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H]2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 M24 compound treatment 109360.0 -43500.0 -1.35 116760.0 -31000.0 -0.81 -1.5234 -0.9698 3559875 ACon1_000576 COc1ccc(cc1)c2oc3cc(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)cc(O)c3c(=O)c2O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N01 compound treatment 109520.0 -43300.0 -1.34 105120.0 -42700.0 -1.11 -1.7337 -0.9955 3558056 ACon1_000577 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCc3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N02 compound treatment 133920.0 -18900.0 -0.59 137320.0 -10500.0 -0.27 -0.6075 -0.939 2118288 ACon1_000578 CCCC#C/C=C/1\OC(=O)C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N03 compound treatment 145960.0 -6900.0 -0.21 135920.0 -11900.0 -0.31 -0.3695 -0.9839 3558083 ACon1_000579 CC(=O)OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N04 compound treatment 79040.0 -73800.0 -2.29 85560.0 -62200.0 -1.62 -2.7609 -0.9856 3553187 ACon1_000580 CC(=CCC/C(=C/COc1cc(=O)oc2cccc(C)c12)/COC(=O)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N05 compound treatment 138880.0 -14000.0 -0.43 153600.0 5800.0 0.15 -0.1997 -0.4355 3173763 ACon1_000581 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N06 compound treatment 173680.0 20800.0 0.65 164240.0 16400.0 0.43 0.7582 0.98 1733214 ACon1_000582 Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N07 compound treatment 113840.0 -39000.0 -1.21 115600.0 -32200.0 -0.84 -1.4465 -0.9838 1043213 ACon1_000583 COC(=O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N08 compound treatment 166480.0 13600.0 0.42 143480.0 -4320.0 -0.11 0.219 0.5016 3558609 ACon1_000584 COc1cc(ccc1O)[C@H]2OC[C@](O)(Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)[C@@H]2CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N09 mock treatment 154160.0 1300.0 0.04 161160.0 13400.0 0.35 0.2739 0.7838 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N10 mock treatment 158120.0 5260.0 0.16 156720.0 8920.0 0.23 0.2791 0.9851 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N11 compound treatment 151040.0 -1820.0 -0.06 127040.0 -20800.0 -0.54 -0.4213 -0.7769 3553255 ACon1_000585 CC(=O)CCCC1Cc2cccc(O)c2C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N12 compound treatment 148480.0 -4380.0 -0.14 140280.0 -7520.0 -0.2 -0.2341 -0.9842 3553375 ACon1_000586 CC(=O)OC[C@@]12CCC(=CC2O[C@@H]3[C@H](O)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@]1(C)C53CO5)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N13 mock treatment 164840.0 12000.0 0.37 149520.0 1720.0 0.04 0.2941 0.7866 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N14 mock treatment 172800.0 19900.0 0.62 162840.0 15000.0 0.39 0.7132 0.9756 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N15 compound treatment 41160.0 -112000.0 -3.46 45560.0 -102000.0 -2.66 -4.3257 -0.9915 1303116 ACon1_000587 Oc1cc(O)c(C(=O)CCc2ccccc2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N16 compound treatment 151280.0 -1580.0 -0.05 116360.0 -31400.0 -0.82 -0.6123 -0.7482 3557944 ACon1_000588 C/C(=C\C(=O)O)/CCC1=C(C)CCC2C(C)(C)CCC[C@@]21C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N17 compound treatment 123800.0 -29100.0 -0.9 113080.0 -34700.0 -0.9 -1.2746 -1.0 3559690 ACon1_000589 COC(=O)C1[C@@H]2Cc3c([nH]c4ccccc34)C(=O)C[C@@H]1/C(=C\C)/CN2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N18 compound treatment 147320.0 -5540.0 -0.17 140920.0 -6880.0 -0.18 -0.2478 -0.9998 3558020 ACon1_000590 OC[C@H]1OC([C@H](O)[C@@H](O)[C@H]1O)c2c(O)cc(O)c3c(=O)cc(oc23)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N19 compound treatment 108800.0 -44100.0 -1.37 91640.0 -56200.0 -1.46 -1.9971 -0.9994 3559729 ACon1_000591 CC1=CC2(CC1CC=C23)CCC4[C@](C)(CO)[C@H](O)CC[C@]43C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N20 compound treatment 160000.0 7140.0 0.22 172280.0 24500.0 0.64 0.6062 0.9001 3558252 ACon1_000592 COc1cc2occc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N21 compound treatment 10680.0 -142000.0 -4.41 12400.0 -135000.0 -3.52 -5.6027 -0.9938 3553911 ACon1_000593 CC1=C2[C@@H]3OC(=O)C(=C)[C@@H]3CC(=O)[C@@]2(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N22 compound treatment 159520.0 6660.0 0.21 157400.0 9600.0 0.25 0.3223 0.9955 3558104 ACon1_000594 CC1CC(=O)[C@@]2(O)[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)OCCc4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N23 compound treatment 122800.0 -30100.0 -0.93 118000.0 -29800.0 -0.77 -1.2061 -0.9958 3554077 ACon1_000595 Cc1cccc2oc(=O)c3c(O[C@@]4(C[C@]3(C)C=C)OC[C@@]5(C)O[C@H]54)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 N24 compound treatment 6840.0 -146000.0 -4.52 6720.0 -141000.0 -3.67 -5.7912 -0.9945 3558467 ACon1_000596 Oc1cc(O)cc(CCCCCCC/C=C\C/C=C\CC=C)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O01 compound treatment 108680.0 -44200.0 -1.37 117720.0 -30100.0 -0.78 -1.5206 -0.9647 3557850 ACon1_000597 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O02 compound treatment 54120.0 -98700.0 -3.06 67720.0 -80100.0 -2.08 -3.6346 -0.9823 3558145 ACon1_000598 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@@H]2OC(=O)[C@@]34CCC(C)(C)CC4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@](C)(C7CC[C@@]6(C)[C@]5(C)CC3)C(=O)O)[C@H](O)[C@H](O)[C@H]1O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O03 compound treatment 155680.0 2820.0 0.09 153960.0 6160.0 0.16 0.1749 0.9594 3554994 ACon1_000599 COc1cc(O)cc(c2cc(O)c(O)cc2C)c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O04 compound treatment 62320.0 -90500.0 -2.81 70680.0 -77100.0 -2.0 -3.4006 -0.9864 3558210 ACon1_000600 Oc1ccc(/C=C/C(=O)NCCCCN(CCCN(CCCNC(=O)\C=C\c2ccc(O)cc2)C(=O)\C=C\c3ccc(O)cc3)C(=O)\C=C\c4ccc(O)cc4)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O05 compound treatment 166520.0 13700.0 0.42 141200.0 -6600.0 -0.17 0.178 0.3898 3558099 ACon1_000601 COc1ccc(cc1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O[C@@H]5O[C@H](CO)C(O)[C@H](O)[C@H]5O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O06 compound treatment 56120.0 -96700.0 -3.0 33560.0 -114000.0 -2.97 -4.2184 -1.0 3557819 ACon1_000602 COC(=O)/C=C(\C)/CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O07 compound treatment 108080.0 -44800.0 -1.39 104760.0 -43000.0 -1.12 -1.7719 -0.9943 3558175 ACon1_000603 CC1CC2OC(=O)C(=C)C2CC=C1CCC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O08 compound treatment 108360.0 -44500.0 -1.38 113400.0 -34400.0 -0.89 -1.607 -0.978 3557525 ACon1_000604 CC1OC(OC2C(O)C(OCCc3ccc(O)c(O)c3)OC(CO)C2OC(=O)/C=C/c4ccc(O)c(O)c4)C(OC5OCC(O)C(O)C5O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O09 compound treatment 148160.0 -4700.0 -0.15 139440.0 -8360.0 -0.22 -0.2566 -0.9811 3614377 ACon1_000605 C[C@H]1[C@H](O)CCC2=CC(=O)[C@@]3(O[C@@H]3[C@]12C)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O10 compound treatment 23720.0 -129000.0 -4.0 27040.0 -121000.0 -3.14 -5.0481 -0.9928 3558377 ACon1_000606 CC(=CCc1c(O)cc2occ(c3ccc(O)cc3O)c(=O)c2c1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O11 mock treatment 172840.0 20000.0 0.62 185160.0 37400.0 0.97 1.1241 0.9764 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O12 mock treatment 170520.0 17700.0 0.55 159440.0 11600.0 0.3 0.6008 0.961 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O13 compound treatment 150480.0 -2380.0 -0.07 146520.0 -1280.0 -0.03 -0.0757 -0.9351 3558336 ACon1_000607 COc1cc(cc(OC)c1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc5OCOc5c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O14 compound treatment 153560.0 698.0 0.02 132800.0 -15000.0 -0.39 -0.2603 -0.6668 3559606 ACon1_000608 COc1cc(CCc2ccc3OCOc3c2)oc(=O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O15 compound treatment 113440.0 -39400.0 -1.22 97520.0 -50300.0 -1.31 -1.7875 -0.9994 3553200 ACon1_000609 CC(=CCCC(C)(O)C(O)CC(OC(=O)C)/C(=C/COCC(O)C(O)C(O)C(O)CO)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O16 compound treatment 32360.0 -121000.0 -3.73 31760.0 -116000.0 -3.02 -4.7721 -0.9944 3074726 ACon1_000610 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5CC[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O17 compound treatment 105920.0 -46900.0 -1.45 105680.0 -42100.0 -1.09 -1.8023 -0.9902 3557679 ACon1_000611 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O18 compound treatment 132560.0 -20300.0 -0.63 147960.0 161.0 0.0 -0.4418 -0.7024 3559274 ACon1_000612 COc1cc(OC)c(O[C@@H]2O[C@H](COC(=O)c3cc(O)c(O)c(O)c3)[C@@H](O)[C@H](O)[C@H]2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O19 compound treatment 31120.0 -122000.0 -3.77 31080.0 -117000.0 -3.03 -4.8117 -0.9941 3557735 ACon1_000613 COC1CC(O[C@H]2CC[C@@]3(C)C(CCC4C3CC[C@]5(C)C(CCC45O)C6=CC(=O)OC6)C2)OC(C)C1OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O20 compound treatment 161560.0 8700.0 0.27 170920.0 23100.0 0.6 0.6154 0.9346 3558277 ACon1_000614 C[C@@H]1O[C@@H](O[C@H]2[C@H](C)O[C@@H](Oc3c(oc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc(O)c4c3=O)c6ccc(O)cc6)[C@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O21 compound treatment 71000.0 -81900.0 -2.54 76120.0 -71700.0 -1.86 -3.1105 -0.9885 3557827 ACon1_000615 OC(CCCCc1ccc(O)cc1)CCc2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O22 compound treatment 138600.0 -14300.0 -0.44 151680.0 3880.0 0.1 -0.2412 -0.5321 3557897 ACon1_000616 C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O23 compound treatment 172680.0 19800.0 0.61 140720.0 -7080.0 -0.18 0.3041 0.4745 3555034 ACon1_000617 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)O[C@@H](C)[C@H](O)[C@H]2OC(=O)C)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 O24 compound treatment 113160.0 -39700.0 -1.23 114400.0 -33400.0 -0.87 -1.4835 -0.9854 3559877 ACon1_000618 OC[C@H]1O[C@@H](Oc2cc(O)c(C(=O)CCc3ccc(O)cc3)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P01 compound treatment 81400.0 -71500.0 -2.21 70520.0 -77300.0 -2.01 -2.9855 -0.9988 3559267 ACon1_000619 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CCC4[C@@]5(C)[C@H]([C@H](O)[C@](C)(CO)C5CC[C@]43C)C(=O)O)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P02 compound treatment 4520.0 -148000.0 -4.6 4720.0 -143000.0 -3.72 -5.8788 -0.9945 3559411 ACon1_000620 CC(C)[C@@H]1CC[C@@]2(C)CCC[C@@](C)(O)[C@@H]2[C@H]1OC(=O)/C=C/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P03 compound treatment 36280.0 -117000.0 -3.61 51720.0 -96100.0 -2.5 -4.3194 -0.9837 3557780 ACon1_000621 C/C(=C\CO)/CC[C@H]1C(=C)CCC2[C@](C)(CCC[C@]12C)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P04 compound treatment 141080.0 -11800.0 -0.37 140040.0 -7760.0 -0.2 -0.4007 -0.9608 1506 ACon1_000622 OCc1cc(=O)c(O)co1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P05 compound treatment 136880.0 -16000.0 -0.5 134040.0 -13800.0 -0.36 -0.6029 -0.9872 3557935 ACon1_000623 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P06 compound treatment 57120.0 -95700.0 -2.97 63200.0 -84600.0 -2.2 -3.6519 -0.9891 3554108 ACon1_000624 CCC(C)/C=C(\C)/C=C/C1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P07 compound treatment 111240.0 -41600.0 -1.29 111280.0 -36500.0 -0.95 -1.5829 -0.9886 1043213 ACon1_000625 COC(=O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P08 compound treatment 156840.0 3980.0 0.12 123280.0 -24500.0 -0.64 -0.3633 -0.5599 3557255 ACon1_000626 OC(=O)C(=C)Oc1cccc(c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P09 compound treatment 130920.0 -21900.0 -0.68 122360.0 -25400.0 -0.66 -0.9481 -0.9999 3559264 ACon1_000627 COc1cc2oc(cc(=O)c2c(O)c1OC)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P10 compound treatment 134240.0 -18600.0 -0.58 122040.0 -25800.0 -0.67 -0.8812 -0.9973 3553970 ACon1_000628 Cc1cc(=O)c2c(O)c3CC(Oc3cc2o1)C(C)(C)OC4OC(CO)C(O)C(O)C4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P11 mock treatment 162800.0 9940.0 0.31 128000.0 -19800.0 -0.51 -0.146 -0.2435 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P12 mock treatment 170920.0 18100.0 0.56 155880.0 8080.0 0.21 0.5441 0.9105 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P13 compound treatment 96680.0 -56200.0 -1.74 79840.0 -68000.0 -1.77 -2.4795 -1.0 3553930 ACon1_000629 CC1=CC(=O)C[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3CC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P14 compound treatment 172920.0 20100.0 0.62 141160.0 -6640.0 -0.17 0.3175 0.4922 3557957 ACon1_000630 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C(C)C(O)CC31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P15 compound treatment 100440.0 -52400.0 -1.62 103840.0 -44000.0 -1.14 -1.9562 -0.9852 3559851 ACon1_000631 COc1cc(O)c(C(=O)/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P16 compound treatment 8040.0 -145000.0 -4.49 10360.0 -137000.0 -3.57 -5.6981 -0.9936 3554298 ACon1_000632 CCCCCCCCCC(O)CC(O)CC(O)CC1CC=CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P17 compound treatment 92080.0 -60800.0 -1.88 86920.0 -60900.0 -1.58 -2.4502 -0.9962 3559696 ACon1_000633 COc1cc2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc5OCOc5c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P18 compound treatment 132760.0 -20100.0 -0.62 110120.0 -37700.0 -0.98 -1.1327 -0.9762 3558198 ACon1_000634 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccc(O)c(O)c6)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P19 compound treatment 73880.0 -79000.0 -2.45 68200.0 -79600.0 -2.07 -3.1929 -0.9965 3559409 ACon1_000635 CC(C)[C@@H]1CC[C@@]2(C)[C@H](O)CC[C@@](C)(O)[C@@H]2[C@@H]1OC(=O)/C=C/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P20 compound treatment 130960.0 -21900.0 -0.68 137040.0 -10800.0 -0.28 -0.6775 -0.9231 3558052 ACon1_000636 COc1cc2ccc(=O)oc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P21 compound treatment 34760.0 -118000.0 -3.66 39040.0 -109000.0 -2.83 -4.5857 -0.9918 1001932 ACon1_000637 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P22 compound treatment 118920.0 -33900.0 -1.05 116520.0 -31300.0 -0.81 -1.3183 -0.9919 3559888 ACon1_000638 Oc1ccc(c(O)c1)c2coc3cc(O)cc(O)c3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P23 compound treatment 118600.0 -34300.0 -1.06 112880.0 -34900.0 -0.91 -1.3922 -0.9969 3559630 ACon1_000639 CC(C)C(=O)OCC(=C)C1Oc2cc(ccc2C1OC(=O)C(C)C)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2291 P24 compound treatment 105640.0 -47200.0 -1.46 97080.0 -50700.0 -1.32 -1.9664 -0.9986 3558347 ACon1_000640 C[C@]1(CCC[C@]2(C)C1CC[C@]3(CC4CC[C@]32O)CC4=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A01 compound treatment 73520.0 -71200.0 -2.21 79640.0 -67500.0 -1.75 -2.8003 -0.9936 3558339 ACon1_000641 COC(=O)C1=C[C@@H](O)[C@@H](O)[C@@H](C1)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)/C=C/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A02 compound treatment 74560.0 -70200.0 -2.17 88000.0 -59200.0 -1.54 -2.624 -0.9856 3558365 ACon1_000642 CC(=CCC/C(=C/C(C/C(=C/C(CC(C)(O)C=C)OC(=O)C)/C)OC(=O)C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A03 compound treatment 82760.0 -62000.0 -1.92 89920.0 -57200.0 -1.49 -2.409 -0.992 3558431 ACon1_000643 CC(=CCC(O)/C(=C/CCC(C)(OC1OC(CO)C(O)C(O)C1O)C=C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A04 compound treatment 77520.0 -67200.0 -2.08 78200.0 -69000.0 -1.79 -2.7392 -0.9972 3559889 ACon1_000644 CCC(=O)OCC1=CCCC2C(C)(CCC(C)CC(=O)O)C(C)CCC21C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A05 compound treatment 108400.0 -36300.0 -1.13 182880.0 35700.0 0.93 -0.1394 -0.0955 3558559 ACon1_000645 COc1cc2ccc(=O)oc2cc1OCC(O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A06 compound treatment 97400.0 -47300.0 -1.47 155120.0 7960.0 0.21 -0.8904 -0.6013 3558221 ACon1_000646 C[C@@H]1CC[C@]2(C)[C@H](CC[C@@H](O)[C@]2(C)O)[C@@]1(C)CC(=O)c3ccoc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A07 compound treatment 72840.0 -71900.0 -2.23 167520.0 20400.0 0.53 -1.2007 -0.5245 3614399 ACon1_000647 COc1cc(O)cc2cc3C[C@](C)(O)CC(=O)c3c(O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A08 compound treatment 51920.0 -92800.0 -2.88 97640.0 -49500.0 -1.29 -2.9429 -0.9342 3559065 ACon1_000648 COc1cc2OC(C)(C)C=Cc2c3oc(cc(=O)c13)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A09 compound treatment 75560.0 -69200.0 -2.14 117760.0 -29400.0 -0.76 -2.0553 -0.9035 3557259 ACon1_000649 COc1c(C)c(oc(=O)c1C)[C@@]2(C)O[C@H]2/C(=C\C(=C\[C@@]3(C)O[C@@H](C)[C@]4(C)OC43)\C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A10 compound treatment 85400.0 -59300.0 -1.84 132600.0 -14600.0 -0.38 -1.567 -0.8351 3559150 ACon1_000650 COc1ccc(cc1O)c2coc3cc(O)ccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A11 compound treatment 102880.0 -41800.0 -1.3 171000.0 23800.0 0.62 -0.4786 -0.3331 3553959 ACon1_000651 CC1C2C(CC(C)(O)C3CC4OC4(C)C3(O)C2=O)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A12 compound treatment 113680.0 -31000.0 -0.96 198040.0 50900.0 1.32 0.2549 0.1559 3614402 ACon1_000652 COc1ccc(cc1)C2Oc3cc(OC)ccc3CC2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A13 mock treatment 124240.0 -20500.0 -0.63 168440.0 21300.0 0.55 -0.0576 -0.0684 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A14 mock treatment 116160.0 -28600.0 -0.88 201000.0 53800.0 1.4 0.3636 0.2196 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A15 compound treatment 119320.0 -25400.0 -0.79 204560.0 57400.0 1.49 0.4982 0.2954 3557496 ACon1_000653 CC(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)/C=C/[C@@]2(O)C(=CC(=O)CC2(C)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A16 compound treatment 119760.0 -25000.0 -0.77 167840.0 20700.0 0.54 -0.1668 -0.1771 3554158 ACon1_000654 CCC(C)C1NC(=O)c2c1n(C)c3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A17 compound treatment 115840.0 -28900.0 -0.89 142560.0 -4600.0 -0.12 -0.7171 -0.7944 3558190 ACon1_000655 C[C@H]1[C@@]2(O)[C@H](CC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@@]32C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)O[C@@]71CCC(C)CO7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A18 compound treatment 100040.0 -44700.0 -1.38 175920.0 28800.0 0.75 -0.4504 -0.2863 3554284 ACon1_000656 CCCCCCC1OC(=O)CCCC(O)/C=C\C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A19 compound treatment 125040.0 -19700.0 -0.61 189520.0 42400.0 1.1 0.3472 0.2759 3551961 ACon1_000657 C/C(=C\C(=O)OC1C(=CC=C(C=O)C1(C)C)C)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A20 compound treatment 120640.0 -24100.0 -0.75 176760.0 29600.0 0.77 0.0164 0.0153 3558454 ACon1_000658 CC1CCC23CCC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C13C(=CC2(C)C)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A21 compound treatment 122600.0 -22100.0 -0.69 136360.0 -10800.0 -0.28 -0.6829 -0.9223 3558413 ACon1_000659 C[C@]1(O)CC[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](COC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A22 compound treatment 49000.0 -95700.0 -2.97 25200.0 -122000.0 -3.17 -4.3378 -0.9995 3553177 ACon1_000660 CC(=C)C(=O)O[C@H]1C[C@@]2(C)OC(=CC2=O)/C(=C\[C@H]3OC(=O)C(=C)C31)/COC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A23 compound treatment 129920.0 -14800.0 -0.46 134000.0 -13200.0 -0.34 -0.5659 -0.9895 3558349 ACon1_000661 CCC(C)C(=O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(=O)CC(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 A24 compound treatment 86680.0 -58000.0 -1.8 65200.0 -82000.0 -2.13 -2.7773 -0.9965 3559855 ACon1_000662 CC/C=C\C=C\C(O)C/C=C\CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B01 compound treatment 84120.0 -60600.0 -1.88 91400.0 -55800.0 -1.45 -2.352 -0.9918 3558522 ACon1_000663 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3C[C@H](O)[C@@](C)(O)[C@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B02 compound treatment 5600.0 -139000.0 -4.31 6600.0 -141000.0 -3.65 -5.6304 -0.9966 3558331 ACon1_000664 CC1OC(OC2C(O)C(O)COC2OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC65C)C(=O)O)C3(C)CO)C(O)C(OC8OCC(OC(=O)C)C(OC(=O)C)C8O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B03 compound treatment 30200.0 -115000.0 -3.55 21480.0 -126000.0 -3.27 -4.818 -0.9991 3558658 ACon1_000665 C[C@@H]1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C(=C)C)[C@@](C)(O)C(=O)[C@H]3O[C@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B04 compound treatment 129040.0 -15700.0 -0.49 154560.0 7400.0 0.19 -0.2075 -0.3971 3557543 ACon1_000666 CC(OC1OC(CO)C(O)C(O)C1O)/C=C/C2(O)C(C)CC(O)CC2(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B05 compound treatment 134120.0 -10600.0 -0.33 149040.0 1880.0 0.05 -0.1976 -0.5951 3558677 ACon1_000667 C[C@@]1(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC[C@@]3(C)[C@H](CCC4=CCOC4=O)C(=C)CC[C@H]13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B06 compound treatment 124160.0 -20600.0 -0.64 152640.0 5480.0 0.14 -0.3497 -0.5357 3559891 ACon1_000668 CC(CO[C@@H]1O[C@H](COC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H](O)[C@H](O)[C@H]1O)C3(O)COC(=O)C3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B07 compound treatment 106000.0 -38700.0 -1.2 148800.0 1640.0 0.04 -0.8181 -0.6815 3558735 ACon1_000669 CC1CCC2(C)C(CCC=C2C(=O)O)C1(C)CCC3=CC(=O)OC3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B08 compound treatment 108560.0 -36200.0 -1.12 155800.0 8640.0 0.22 -0.6334 -0.5543 3557836 ACon1_000670 COc1cc(/C=C/C(=O)O[C@@H]2[C@@H](CO[C@@H]3OC[C@](O)(CO)[C@H]3O)O[C@@H](OCCc4ccc(O)c(O)c4)[C@H](O)[C@H]2O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B09 compound treatment 123120.0 -21600.0 -0.67 154520.0 7360.0 0.19 -0.3379 -0.4855 3558686 ACon1_000671 COc1cc(/C=C/C(=O)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2OC(=O)\C=C\c4cc(OC)c(O)c(OC)c4)cc(OC)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B10 compound treatment 104840.0 -39900.0 -1.24 141800.0 -5360.0 -0.14 -0.9721 -0.7818 1417265 ACon1_000672 OC1CCn2c1nc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B11 compound treatment 24880.0 -120000.0 -3.71 46480.0 -101000.0 -2.62 -4.4752 -0.9853 3557345 ACon1_000673 CC(=O)c1c(O)cc(O)c(C(=O)C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B12 compound treatment 77120.0 -67600.0 -2.09 135000.0 -12200.0 -0.32 -1.7044 -0.8046 3558110 ACon1_000674 COc1cc(/C=C/c2ccccc2)cc(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B13 mock treatment 139200.0 -5520.0 -0.17 148680.0 1520.0 0.04 -0.0929 -0.5293 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B14 mock treatment 143320.0 -1400.0 -0.04 144800.0 -2360.0 -0.06 -0.0739 -0.9857 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B15 compound treatment 108280.0 -36400.0 -1.13 146760.0 -396.0 -0.01 -0.8056 -0.7135 3559744 ACon1_000675 CC(CCO)CC[C@@H]1C(=C)CC[C@@H]2[C@@](C)(CCC[C@@]12C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B16 compound treatment 28200.0 -117000.0 -3.61 61520.0 -85600.0 -2.23 -4.1262 -0.973 3553396 ACon1_000676 CC(=O)OCC1(C)CC2[C@]3(CO[C@]42CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]3O)[C@@H](O)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B17 compound treatment 108240.0 -36500.0 -1.13 182560.0 35400.0 0.92 -0.1487 -0.1021 3489715 ACon1_000677 CC1CCC2(CCC3(C(=O)O)C(=CCC4C5(C)CCC(OC6OC(C)C(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1C)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B18 compound treatment 129720.0 -15000.0 -0.46 158200.0 11000.0 0.29 -0.1257 -0.2301 3557359 ACon1_000678 CC(C)[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)n4c1nc5ccccc5c4=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B19 compound treatment 131800.0 -12900.0 -0.4 156200.0 9040.0 0.23 -0.1169 -0.2518 3558569 ACon1_000679 CC1=C(CCC2=CC(O)OC2=O)[C@@]3(C)CCC[C@@]4(C)[C@@H]3C(OC4=O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B20 compound treatment 157720.0 13000.0 0.4 174520.0 27400.0 0.71 0.7876 0.9638 3557575 ACon1_000680 OCCc1ccc(O)c(OC2OC(CO)C(O)C(O)C2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B21 compound treatment 142520.0 -2200.0 -0.07 158680.0 11500.0 0.3 0.1636 0.5327 3557374 ACon1_000681 C/C=C/C=C/C1C=CC2CC(C)CCC2C1(C)\C(=C/3\C(=O)NC(C(C)O)C3=O)\O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B22 compound treatment 156640.0 11900.0 0.37 193840.0 46700.0 1.21 1.1189 0.8824 3558646 ACon1_000682 CC(C)(O)CCC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(CC(O)C(OC5OC(CO)C(O)C(O)C5O)C4(C)C)C3(C)C(=O)CC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B23 compound treatment 133520.0 -11200.0 -0.35 183080.0 35900.0 0.93 0.4147 0.4164 3558270 ACon1_000683 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@@H](O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H]2OC(=O)/C=C/c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 B24 compound treatment 112680.0 -32000.0 -0.99 123640.0 -23500.0 -0.61 -1.134 -0.9728 3558889 ACon1_000684 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)OC7OC(CO)C(O)C(O)C7O)C2(C)C)[C@H](O)[C@@H](O)[C@@H]1OC8OC(CO)C(O)C(O)C8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C01 compound treatment 92480.0 -52200.0 -1.62 125560.0 -21600.0 -0.56 -1.5413 -0.8997 3558360 ACon1_000685 COC(=O)[C@]1(C)CC[C@H](OC(=O)C)[C@@]2(C)C1C[C@@H](OC(=O)C)C3=C2CC[C@](C)(C=C)[C@@H]3OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C02 compound treatment 29840.0 -115000.0 -3.56 33960.0 -113000.0 -2.94 -4.5966 -0.9955 3558319 ACon1_000686 C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CCC3=C2)c6ccc(=O)oc6)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C03 compound treatment 76400.0 -68300.0 -2.12 67840.0 -79300.0 -2.06 -2.954 -0.9999 3558457 ACon1_000687 CC(CC[C@@]1(C)[C@H](C)CC[C@]2(C)C1CCC=C2CO)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C04 compound treatment 132560.0 -12200.0 -0.38 152280.0 5120.0 0.13 -0.1722 -0.4311 3553465 ACon1_000688 CC(C)(O)[C@@H]1CC[C@]2(CO)[C@@H](O)CC[C@](C)(O)[C@H]2[C@@H]1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C05 compound treatment 117280.0 -27400.0 -0.85 126920.0 -20200.0 -0.53 -0.9729 -0.9733 3558579 ACon1_000689 COc1cc2OC(CC(=O)c2c(O)c1OC)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C06 compound treatment 115640.0 -29100.0 -0.9 147800.0 644.0 0.02 -0.6252 -0.6938 3554662 ACon1_000690 COC(=O)C1(Cc2ccc(O)cc2)OC(=O)C(=C1c3ccc(O)cc3)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C07 compound treatment 116840.0 -27900.0 -0.86 145840.0 -1320.0 -0.03 -0.635 -0.7345 3558617 ACon1_000691 COC(=O)C1=COC(O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OCCc4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C08 compound treatment 101080.0 -43600.0 -1.35 164520.0 17400.0 0.45 -0.6371 -0.4469 3559200 ACon1_000692 COc1cc2occ(c3ccc4OCOc4c3)c(=O)c2c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C09 compound treatment 49640.0 -95100.0 -2.95 100080.0 -47100.0 -1.22 -2.948 -0.9242 3554819 ACon1_000693 COc1cc(=O)oc(/C(=C/C(=C/C(=C/C2(C)OC(C)C3(C)OC32)/C)/C)/C)c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C10 compound treatment 8640.0 -136000.0 -4.22 12880.0 -134000.0 -3.49 -5.4484 -0.9956 3558246 ACon1_000694 CC(C)C(=O)c1c(O)cc2OC(C)(C)C(CC=C(C)C)Cc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C11 mock treatment 64560.0 -80200.0 -2.48 145680.0 -1480.0 -0.04 -1.7833 -0.7179 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C12 mock treatment 46840.0 -97900.0 -3.03 163480.0 16300.0 0.42 -1.8445 -0.6023 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C13 compound treatment 128880.0 -15800.0 -0.49 191360.0 44200.0 1.15 0.4651 0.3724 3558047 ACon1_000695 COc1cc(CCO)ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C14 compound treatment 115680.0 -29000.0 -0.9 173360.0 26200.0 0.68 -0.1548 -0.1372 3614417 ACon1_000696 COC1CC(OC(O)C(O)C(O)C(O)C(O)CO)c2c(O)c3c(=O)oc(C)cc3cc2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C15 mock treatment 137680.0 -7040.0 -0.22 188320.0 41200.0 1.07 0.6021 0.5516 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C16 mock treatment 133640.0 -11100.0 -0.34 154680.0 7520.0 0.2 -0.1045 -0.2645 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C17 compound treatment 117320.0 -27400.0 -0.85 149600.0 2440.0 0.06 -0.5554 -0.6524 3558236 ACon1_000697 CC(C)C1(CC12)C(=O)CC2(C)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C18 compound treatment 10520.0 -134000.0 -4.16 13480.0 -134000.0 -3.47 -5.3962 -0.996 3557265 ACon1_000698 CC(=CCC/C(=C/CC/C(=C/Cc1c(C)cc(O)cc1O)/C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C19 compound treatment 84200.0 -60500.0 -1.88 103680.0 -43500.0 -1.13 -2.1247 -0.9706 3558297 ACon1_000699 CC(C)c1cc2CCC3C(C)(C)CCC[C@]3(C(=O)O)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C20 compound treatment 154920.0 10200.0 0.32 172800.0 25600.0 0.67 0.6947 0.9419 3558260 ACon1_000700 CC(C)C(O)(C(C)O)C(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C21 compound treatment 48160.0 -96600.0 -2.99 12920.0 -134000.0 -3.49 -4.5818 -0.9971 3558324 ACon1_000701 CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C22 compound treatment 134720.0 -10000.0 -0.31 171040.0 23900.0 0.62 0.2198 0.3168 3558258 ACon1_000702 C[C@H](O)C1=CC2(CC[C@H]3[C@@H]2[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C23 compound treatment 98520.0 -46200.0 -1.43 76240.0 -70900.0 -1.84 -2.3151 -0.9922 3555893 ACon1_000703 OC[C@H]1O[C@@H](Oc2cc(C(=O)O)c(O)c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 C24 compound treatment 117000.0 -27700.0 -0.86 126560.0 -20600.0 -0.54 -0.9857 -0.9741 3557293 ACon1_000704 COC(=O)c1cccc2oc3cc(CO)cc(O)c3c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D01 compound treatment 12200.0 -133000.0 -4.11 20320.0 -127000.0 -3.3 -5.2337 -0.9941 3557722 ACon1_000705 COc1ccc2ccc(=O)oc2c1CC(O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D02 compound treatment 143800.0 -918.0 -0.03 154000.0 6840.0 0.18 0.1056 0.5865 3553508 ACon1_000706 CC(C)C(=O)O[C@@H]1[C@@H](OC(=O)C)[C@@H](OC(=O)C)C(C)(C)/C=C/[C@@](C)(O)C(=O)[C@@]2(O)[C@H](OC(=O)C)[C@@](C)(OC(=O)C)[C@H](OC(=O)C)[C@@H]2[C@H]3OC(=O)CC[C@]31OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D03 compound treatment 163760.0 19000.0 0.59 171480.0 24300.0 0.63 0.8641 0.9994 3558643 ACon1_000707 COc1cc(OC2OC(COC3OCC(O)(CO)C3O)C(O)C(O)C2O)c4c(cc(=O)oc4c1)c5ccc(O)c(O)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D04 compound treatment 175360.0 30600.0 0.95 171040.0 23900.0 0.62 1.1102 0.9788 1279467 ACon1_000708 COC(=O)C(Cc1ccccc1)NC(=O)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D05 compound treatment 162560.0 17800.0 0.55 167080.0 19900.0 0.52 0.757 0.9995 3614423 ACon1_000709 COC(=O)C1=CC=CC(CC(O)C(=O)O)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D06 compound treatment 178200.0 33500.0 1.04 183000.0 35800.0 0.93 1.3921 0.9986 3558535 ACon1_000710 C[C@@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C2(C)C)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D07 compound treatment 152480.0 7760.0 0.24 167920.0 20800.0 0.54 0.5516 0.9337 3614426 ACon1_000711 CC1CC(=O)C2=C(O1)OC3(C)CCC4(O)C(C)(C)C5OC5C(=O)C4(C)C3C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D08 compound treatment 79320.0 -65400.0 -2.03 136080.0 -11100.0 -0.29 -1.6363 -0.7995 3554252 ACon1_000712 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCC(O)COP(=O)(O)OCC[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D09 compound treatment 109800.0 -34900.0 -1.08 145800.0 -1360.0 -0.04 -0.7899 -0.7297 3558720 ACon1_000713 COc1cc(/C=C/c2cc(O)cc(O)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D10 compound treatment 166280.0 21600.0 0.67 139000.0 -8160.0 -0.21 0.3226 0.4602 3554771 ACon1_000714 COc1c(O)ccc2C([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4cc(C)cc(O)c4C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D11 mock treatment 137920.0 -6800.0 -0.21 141080.0 -6080.0 -0.16 -0.2606 -0.9899 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D12 mock treatment 98080.0 -46600.0 -1.45 127480.0 -19700.0 -0.51 -1.3833 -0.9025 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D13 compound treatment 159800.0 15100.0 0.47 182120.0 35000.0 0.91 0.9728 0.9522 3614428 ACon1_000715 COC(=O)c1c(C)cc2CC3(Oc2c(C)c1=O)C(C)CCC(C(C)(C)O)C3(C)CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D14 compound treatment 168120.0 23400.0 0.73 149200.0 2040.0 0.05 0.5503 0.7569 3553648 ACon1_000716 CC(C)CC1NC(=O)C2CCCN2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D15 mock treatment 139120.0 -5600.0 -0.17 134040.0 -13100.0 -0.34 -0.3636 -0.9509 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D16 mock treatment 152920.0 8200.0 0.25 145200.0 -1960.0 -0.05 0.1438 0.5547 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D17 compound treatment 145520.0 802.0 0.02 170680.0 23500.0 0.61 0.4498 0.7352 3558202 ACon1_000717 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)C)[C@H]1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D18 compound treatment 181640.0 36900.0 1.14 149800.0 2640.0 0.07 0.8575 0.7482 3558526 ACon1_000718 COc1ccc2ccc(=O)oc2c1CC(O)C(C)(C)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D19 compound treatment 172080.0 27400.0 0.85 195160.0 48000.0 1.25 1.4814 0.9823 3614429 ACon1_000719 COc1cccc2oc3OC=C(CO)C=C(C(=O)O)c3c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D20 compound treatment 178080.0 33400.0 1.03 144920.0 -2240.0 -0.06 0.6899 0.6663 3558603 ACon1_000720 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)O[C@@H]6OC[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D21 compound treatment 180800.0 36100.0 1.12 161280.0 14100.0 0.37 1.05 0.8924 3614430 ACon1_000721 C[C@@H]1C[C@H]2OC(=O)[C@@]3(C)CCC[C@](C)(C23)[C@@]1(O)CCC4=CC(=O)OC4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D22 compound treatment 220040.0 75300.0 2.33 189200.0 42000.0 1.09 2.4227 0.9402 3558751 ACon1_000722 COc1ccc(cc1OC)[C@@H]2O[C@H]([C@@H](C)[C@@H]2C)c3ccc(OC)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D23 compound treatment 150640.0 5920.0 0.18 178120.0 31000.0 0.8 0.6986 0.8466 3554692 ACon1_000723 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OC[C@H]3O[C@@H](OCCc4ccc(O)cc4)[C@H](OC(=O)CC5\C(=C\C)\C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)OC=C5C(=O)OC)[C@@H](O)[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 D24 compound treatment 48720.0 -96000.0 -2.97 30200.0 -117000.0 -3.04 -4.252 -0.9999 3554061 ACon1_000724 CC1CCC/C=C/C(=O)c2c(O)cc(O)cc2CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E01 mock treatment 102280.0 -42400.0 -1.31 133280.0 -13900.0 -0.36 -1.1847 -0.8689 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E02 mock treatment 126200.0 -18500.0 -0.57 170760.0 23600.0 0.61 0.028 0.0333 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E03 compound treatment 116480.0 -28200.0 -0.87 112400.0 -34800.0 -0.9 -1.2572 -0.9999 3558404 ACon1_000725 CC(C)c1ccc2c(CCC3[C@@](C)(CCC[C@@]32C)C(=O)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E04 compound treatment 117560.0 -27200.0 -0.84 157120.0 9960.0 0.26 -0.4119 -0.4679 3558499 ACon1_000726 OCC1OC(Oc2ccc(/C=C/C(=O)OC3COC(OCC4OC(OC(C#N)c5ccccc5)C(O)C(O)C4O)C(O)C3O)cc2)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E05 compound treatment 107480.0 -37200.0 -1.15 125080.0 -22100.0 -0.57 -1.2214 -0.948 3558134 ACon1_000727 Cc1c(O)cc2OC(CC(=O)c2c1O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E06 compound treatment 116080.0 -28600.0 -0.89 122960.0 -24200.0 -0.63 -1.072 -0.9858 2082654 ACon1_000728 COc1ccc(cc1OC)c2oc3c(OC)c(OC)c(OC)c(O)c3c(=O)c2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E07 compound treatment 117280.0 -27400.0 -0.85 131040.0 -16100.0 -0.42 -0.8972 -0.9468 3557964 ACon1_000729 CC(=O)OC1C(O)C(O)C(CO)OC1Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E08 compound treatment 24760.0 -120000.0 -3.72 41360.0 -106000.0 -2.75 -4.5719 -0.989 3614436 ACon1_000730 COc1ccc(cc1)c2coc3c(CC=C(C)C)c(O)c(OC)cc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E09 mock treatment 117960.0 -26800.0 -0.83 130440.0 -16700.0 -0.43 -0.8934 -0.9545 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E10 mock treatment 130760.0 -14000.0 -0.43 138000.0 -9160.0 -0.24 -0.474 -0.9604 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E11 compound treatment 68960.0 -75800.0 -2.35 77400.0 -69800.0 -1.81 -2.9414 -0.9918 1102884 ACon1_000731 Cc1cc(O)c(O)c(Oc2cc(C)cc(O)c2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E12 compound treatment 96440.0 -48300.0 -1.5 108480.0 -38700.0 -1.0 -1.7683 -0.9813 3614439 ACon1_000732 Cc1cc(O)c(C)c2OC(=O)c3c(C)cc(O)c(C)c3Oc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E13 compound treatment 139840.0 -4880.0 -0.15 134520.0 -12600.0 -0.33 -0.339 -0.938 3558045 ACon1_000733 O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)/C=C/c2ccccc2)[C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E14 compound treatment 130640.0 -14100.0 -0.44 145040.0 -2120.0 -0.05 -0.3473 -0.79 3557896 ACon1_000734 CC1OC(OCC2OC(Oc3cc(O)c4c(=O)c(coc4c3)c5ccc(O)cc5)C(O)C(O)C2O)C(O)C(O)C1OC6OC(CO)C(O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E15 compound treatment 125320.0 -19400.0 -0.6 144600.0 -2560.0 -0.07 -0.472 -0.7805 3555889 ACon1_000735 OC[C@H]1O[C@@H](OC/C/2=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](O)C/C(=C\CC2)/C=O)[C@H](OC(=O)Cc4ccc(O)cc4)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E16 compound treatment 93560.0 -51200.0 -1.59 111920.0 -35200.0 -0.92 -1.7682 -0.966 3557786 ACon1_000736 CC1(C)[C@@H](O)C(=O)C[C@@]2(C)C1CC[C@@]3(C)O[C@](C)(CCC32)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E17 mock treatment 124800.0 -19900.0 -0.62 148280.0 1120.0 0.03 -0.4157 -0.6729 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E18 mock treatment 119960.0 -24800.0 -0.77 140440.0 -6720.0 -0.17 -0.6658 -0.8463 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E19 compound treatment 142880.0 -1840.0 -0.06 143600.0 -3560.0 -0.09 -0.1056 -0.973 3558389 ACon1_000737 CC(C)C1CC=C(C)C(O)CCC(=C)CC1OC2OC(COC(=O)C)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E20 compound treatment 151120.0 6400.0 0.2 155520.0 8360.0 0.22 0.2939 0.999 3558256 ACon1_000738 OC[C@H]1O[C@@H](Oc2ccc(/C=C/C(=O)O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E21 compound treatment 133280.0 -11400.0 -0.35 151240.0 4080.0 0.11 -0.1756 -0.4745 3558369 ACon1_000739 C[C@@H]1C[C@H]2OC(=O)[C@@]3(C)CCC[C@](C)(C23)[C@@]1(O)CCc4ccoc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E22 compound treatment 86240.0 -58500.0 -1.81 101280.0 -45900.0 -1.19 -2.1241 -0.9794 3558332 ACon1_000740 Oc1ccc(cc1O)C2OC[C@@H]3[C@H](OC[C@H]23)c4ccc5OCOc5c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E23 compound treatment 151720.0 7000.0 0.22 160520.0 13400.0 0.35 0.3989 0.9744 3558345 ACon1_000741 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](OC(=O)C)[C@@H]2OC(=O)C)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 E24 compound treatment 100720.0 -44000.0 -1.36 126040.0 -21100.0 -0.55 -1.3519 -0.92 3557578 ACon1_000742 OCC1OC(C(O)C(O)C1O)c2c(O)cc3oc(cc(=O)c3c2O)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F01 mock treatment 136800.0 -7920.0 -0.25 155480.0 8320.0 0.22 -0.0205 -0.0628 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F02 mock treatment 155560.0 10800.0 0.34 145800.0 -1360.0 -0.04 0.2126 0.6295 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F03 compound treatment 134760.0 -9960.0 -0.31 128600.0 -18600.0 -0.48 -0.5591 -0.9767 3558651 ACon1_000743 C[C@@H]1C[C@@H](O)C2[C@@](C)(CO)CCC[C@]2(C)[C@@]1(O)CCc3ccoc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F04 compound treatment 174960.0 30200.0 0.94 157800.0 10600.0 0.28 0.8581 0.8784 3614448 ACon1_000744 COC(CC(OC)c1c(O)cc2cc(C)oc(=O)c2c1O)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F05 compound treatment 20240.0 -124000.0 -3.86 18040.0 -129000.0 -3.35 -5.0994 -0.9976 3552924 ACon1_000745 C[C@H](CCC(=C)[C@@H](C)C(=O)O)[C@H]1CCC2(C)C3=C(C[C@H](O)[C@]12C)[C@@]4(C)CC[C@@H](OC(=O)CC(=O)O)C(C)(C)C4CC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F06 compound treatment 157440.0 12700.0 0.39 160000.0 12800.0 0.33 0.5147 0.9966 3554676 ACon1_000746 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCc3ccc(OC(=O)C[C@H]4\C(=C/C)\[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)OC=C4C(=O)OC)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F07 compound treatment 11120.0 -134000.0 -4.14 13160.0 -134000.0 -3.48 -5.3889 -0.9963 3554523 ACon1_000747 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)\C(=C/C)\C)C1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F08 compound treatment 118400.0 -26300.0 -0.82 125480.0 -21700.0 -0.56 -0.9748 -0.9837 3558636 ACon1_000748 CC(O)CCC1=CC[C@H]2OC(=O)C(=C)[C@@H]2CC1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F09 mock treatment 144880.0 162.0 0.01 132640.0 -14500.0 -0.38 -0.2631 -0.6976 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F10 mock treatment 133200.0 -11500.0 -0.36 129880.0 -17300.0 -0.45 -0.5698 -0.9935 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F11 compound treatment 160360.0 15600.0 0.48 136880.0 -10300.0 -0.27 0.1539 0.2782 3558527 ACon1_000749 COc1ccc2ccc(=O)oc2c1C(OC(=O)C)C(=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F12 compound treatment 12040.0 -133000.0 -4.11 13320.0 -134000.0 -3.48 -5.3658 -0.9965 3558182 ACon1_000750 C/C=C(\C)/C(=O)O[C@H]1[C@H](OC(=O)C)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H]6O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@]43C)C2CC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F13 compound treatment 45680.0 -99000.0 -3.07 52200.0 -95000.0 -2.47 -3.9144 -0.9942 3559736 ACon1_000751 CC(C)C(=O)O[C@@H]1c2c(C)coc2C(=O)[C@@H]3[C@@H](OC(=O)C=C(C)C)[C@H](O)C[C@H](C)[C@@]13C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F14 compound treatment 70960.0 -73800.0 -2.29 83600.0 -63600.0 -1.65 -2.7837 -0.9873 3553501 ACon1_000752 CC(C)[C@]1(O)CC2=CC[C@H](OC1=O)/C(=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](C2)OC(=O)/C(=C/CO)/CO)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F15 compound treatment 104320.0 -40400.0 -1.25 145480.0 -1680.0 -0.04 -0.9159 -0.7313 3559723 ACon1_000753 C/C(=C\CO)/C(=O)O[C@@H]1C\C(=C\CC[C@@]2(CO)OC2[C@H]3OC(=O)C(=C)C31)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F16 compound treatment 155640.0 10900.0 0.34 149800.0 2640.0 0.07 0.2879 0.8337 3558093 ACon1_000754 COC1CC(O[C@H]2CC[C@]3(C)C4[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(C)[C@H](CC[C@]5(O)C4CC=C3C2)C(=O)C)OC(C)C1OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F17 mock treatment 143800.0 -918.0 -0.03 132400.0 -14800.0 -0.38 -0.2912 -0.7575 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F18 mock treatment 128480.0 -16200.0 -0.5 135640.0 -11500.0 -0.3 -0.5673 -0.9692 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F19 compound treatment 154040.0 9320.0 0.29 157200.0 10000.0 0.26 0.3888 0.9987 3554275 ACon1_000755 CCCCCC1=C(O)/C(=C/C(=O)O)/OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F20 compound treatment 153000.0 8280.0 0.26 139560.0 -7600.0 -0.2 0.0419 0.1294 3558634 ACon1_000756 CCC(C)(O)CC(=O)O[C@H]/1C[C@@H]2[C@H](OC(=O)C2=C)[C@@H]3O[C@]3(C)CC\C=C1/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F21 compound treatment 142280.0 -2440.0 -0.08 144800.0 -2360.0 -0.06 -0.0967 -0.9945 3614460 ACon1_000757 CCC(C)/C=C(\C)/C=C/C1=CC2=C(Cl)C(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F22 compound treatment 139200.0 -5520.0 -0.17 166680.0 19500.0 0.51 0.2378 0.4442 3555003 ACon1_000758 COc1cc(oc(=O)c1)c2c(C)cc(O)cc2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F23 compound treatment 152840.0 8120.0 0.25 129560.0 -17600.0 -0.46 -0.1453 -0.2785 3557852 ACon1_000759 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@](C)(C5CC[C@]43C)C(=O)O)C2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 F24 compound treatment 87160.0 -57600.0 -1.78 135920.0 -11200.0 -0.29 -1.4675 -0.812 3558059 ACon1_000760 COc1ccc(cc1)C2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](OC5OCC(O)(CO)C5O)[C@H](O)[C@H]4O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G01 compound treatment 106200.0 -38500.0 -1.19 116880.0 -30300.0 -0.79 -1.4001 -0.9795 3558424 ACon1_000761 COc1ccc(cc1)c2coc3c(OC)c(OC)cc(OC4OC(CO)C(O)C(O)C4OC5OCC(O)C(O)C5O)c3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G02 compound treatment 113760.0 -31000.0 -0.96 152400.0 5240.0 0.14 -0.5819 -0.6006 3558440 ACon1_000762 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H](C(=C)CO)[C@@](C)(C[C@@H]2O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G03 mock treatment 136000.0 -8720.0 -0.27 140880.0 -6280.0 -0.16 -0.3063 -0.9708 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G04 mock treatment 133960.0 -10800.0 -0.33 141600.0 -5560.0 -0.14 -0.3378 -0.9299 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G05 compound treatment 126440.0 -18300.0 -0.57 132080.0 -15100.0 -0.39 -0.6774 -0.9838 3552674 ACon1_000763 C[C@@H]1CC(=O)[C@]2(COC(=O)C)[C@H](CC[C@H](O)[C@@]32CO3)[C@]41C[C@H](OC4=O)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G06 compound treatment 132640.0 -12100.0 -0.37 142120.0 -5040.0 -0.13 -0.3571 -0.9009 3557361 ACon1_000764 COc1cc(OC)c2c(=O)oc(CC(O)CC(=O)C)cc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G07 compound treatment 92840.0 -51900.0 -1.61 113520.0 -33600.0 -0.87 -1.7546 -0.959 1080935 ACon1_000765 Cc1c(O)cc2OC(CC(=O)c2c1O)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G08 compound treatment 101400.0 -43300.0 -1.34 134040.0 -13100.0 -0.34 -1.19 -0.8594 3614466 ACon1_000766 COc1cc(O)c-2c(CCc3cc(OC)c(OC)cc32)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G09 compound treatment 103920.0 -40800.0 -1.26 113800.0 -33400.0 -0.87 -1.5067 -0.983 3557989 ACon1_000767 CC(C)(O)C1Oc2cc3occ(c4ccc(O)cc4)c(=O)c3c(O)c2C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G10 compound treatment 13240.0 -131000.0 -4.07 13720.0 -133000.0 -3.47 -5.3322 -0.9968 3559169 ACon1_000768 COc1ccc(cc1)C(O)CNC(=O)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G11 compound treatment 124040.0 -20700.0 -0.64 159520.0 12400.0 0.32 -0.2259 -0.3151 3558069 ACon1_000769 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C)[C@H]3CCC(CO)[C@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G12 compound treatment 147680.0 2960.0 0.09 142480.0 -4680.0 -0.12 -0.021 -0.138 3555309 ACon1_000770 COc1cccc2C(=O)OC(c21)c3ccc4C(O)C(C)CC(=O)c4c3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G13 compound treatment 135960.0 -8760.0 -0.27 128240.0 -18900.0 -0.49 -0.5394 -0.9608 3558151 ACon1_000771 OC[C@H]1O[C@@H](OC/C/2=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](O)C/C(=C\CC2)/C=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G14 compound treatment 129880.0 -14800.0 -0.46 127160.0 -20000.0 -0.52 -0.6925 -0.9981 3557929 ACon1_000772 C[C@@]12C[C@@H](O)[C@@H]3C[C@@]2(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@]3(COC(=O)c5ccccc5)C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G15 compound treatment 133760.0 -11000.0 -0.34 146000.0 -1160.0 -0.03 -0.2613 -0.7666 3558123 ACon1_000773 COc1ccc(/C=C/C(=O)O[C@]2(C)CCC3[C@@H]2[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G16 compound treatment 136680.0 -8040.0 -0.25 141920.0 -5240.0 -0.14 -0.2723 -0.9595 3557915 ACon1_000774 COc1c(OC2OC(CO)C(O)C(O)C2O)ccc(O)c1C(=O)OCc3ccccc3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G17 compound treatment 142080.0 -2640.0 -0.08 145440.0 -1720.0 -0.04 -0.0893 -0.9593 3614471 ACon1_000775 COc1cc(/C=C/C(=O)NCC(O)c2ccc(O)cc2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G18 compound treatment 128800.0 -15900.0 -0.49 161040.0 13900.0 0.36 -0.0937 -0.1533 3558265 ACon1_000776 COc1ccc(cc1)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G19 mock treatment 141800.0 -2920.0 -0.09 142520.0 -4640.0 -0.12 -0.1491 -0.99 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G20 mock treatment 139040.0 -5680.0 -0.18 155880.0 8720.0 0.23 0.0359 0.1251 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G21 compound treatment 147600.0 2880.0 0.09 158400.0 11200.0 0.29 0.2697 0.8829 3558300 ACon1_000777 CC(CO)C(=O)O[C@H]1C[C@@]2(C)[C@H](O)CCC(=O)[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G22 compound treatment 139680.0 -5040.0 -0.16 146240.0 -916.0 -0.02 -0.1272 -0.8056 1047948 ACon1_000778 COc1cc(cc(OC)c1OC)C2OCC3C(OCC23)c4cc(OC)c(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G23 compound treatment 23000.0 -122000.0 -3.77 9240.0 -138000.0 -3.58 -5.2006 -0.9997 3558322 ACon1_000779 CC(C)c1cc2C(O)C[C@H]3C(C)(C)CCC[C@]3(C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 G24 compound treatment 104280.0 -40400.0 -1.25 117360.0 -29800.0 -0.77 -1.4334 -0.9732 3558519 ACon1_000780 OCC1C(O)CC2C1C(=O)OCC2=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H01 compound treatment 121920.0 -22800.0 -0.71 117480.0 -29700.0 -0.77 -1.0447 -0.999 3614474 ACon1_000781 COc1c2C(=O)OCc2c(C)c3OC4(C)CC(O)C5(O)C(C)(CCC(=O)OC5(C)C)C4Cc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H02 compound treatment 10720.0 -134000.0 -4.15 9440.0 -138000.0 -3.58 -5.466 -0.9973 3558708 ACon1_000782 C[C@@H]/1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C(=C)C)[C@@](C)(O)C(=O)/C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H03 mock treatment 145240.0 522.0 0.02 140600.0 -6560.0 -0.17 -0.109 -0.6371 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H04 mock treatment 141040.0 -3680.0 -0.11 165840.0 18700.0 0.49 0.2627 0.5268 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H05 compound treatment 128240.0 -16500.0 -0.51 124840.0 -22300.0 -0.58 -0.771 -0.998 3552202 ACon1_000783 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](CC(O)C3=CCOC3=O)C(=C)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H06 compound treatment 12440.0 -132000.0 -4.1 12000.0 -135000.0 -3.51 -5.3813 -0.997 3558285 ACon1_000784 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@@H](O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)[C@H](O)C[C@]5(C)C4CC[C@]23C)O[C@@]%101CCC(C)CO%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H07 compound treatment 101240.0 -43500.0 -1.35 107320.0 -39800.0 -1.04 -1.6845 -0.9915 3558479 ACon1_000785 C[C@@]1(CCC2=C(C1)C(=O)CC3[C@@](C)(CCC[C@@]32C)C(=O)O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H08 compound treatment 103360.0 -41400.0 -1.28 117560.0 -29600.0 -0.77 -1.4499 -0.9702 3553528 ACon1_000786 CC(C)C(=O)OC/C(=C/CCC(=C)C1CC=C(CO)C(C1)OC(=O)C(C)C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H09 compound treatment 154880.0 10200.0 0.31 147960.0 804.0 0.02 0.2374 0.7524 3558737 ACon1_000787 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H10 compound treatment 86080.0 -58600.0 -1.82 144520.0 -2640.0 -0.07 -1.3331 -0.7332 3559235 ACon1_000788 CC1OC(O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)OC7OC(CO)C(OC8OC(CO)C(O)C(O)C8O)C(O)C7O)C2(C)C)C(O)C(O)C1OC9OCC(O)(COC%10OCC(O)C(OC%11OCC(OC%12OCC(O)(CO)C%12O)C(O)C%11O)C%10O)C9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H11 compound treatment 138760.0 -5960.0 -0.18 138480.0 -8680.0 -0.23 -0.2899 -0.9951 3557942 ACon1_000789 CC1CCC2(C)C(CC(=O)C=C2C)C1(C)CC/C(=C\C(=O)O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H12 compound treatment 154680.0 9960.0 0.31 186920.0 39800.0 1.03 0.9488 0.8799 3552656 ACon1_000790 C[C@@H]1C[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@]2(COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)c3ccccc3)[C@@H]4[C@@H](OC(=O)C)[C@]12OC4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H13 compound treatment 140040.0 -4680.0 -0.14 137840.0 -9320.0 -0.24 -0.2736 -0.9699 1712662 ACon1_000791 COc1ccc2CC(=O)c3cc4OCOc4cc3CCN(C)Cc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H14 compound treatment 143320.0 -1400.0 -0.04 156120.0 8960.0 0.23 0.1341 0.5659 3557252 ACon1_000792 CC1CCC2C(C)(C)[C@@H](O)CC[C@]2(C)C31Cc4c(O3)c5CN(C(CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H15 compound treatment 151720.0 7000.0 0.22 139120.0 -8040.0 -0.21 0.0058 0.0192 3559760 ACon1_000793 COc1cc(OC)c2c(=O)c(OC)c(oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H16 compound treatment 151880.0 7160.0 0.22 166440.0 19300.0 0.5 0.5112 0.9329 3558095 ACon1_000794 COC1CC(O[C@H]2CC[C@]3(C)C4[C@H](OC(=O)C)[C@@H](OC(=O)/C(=C/C)/C)[C@]5(C)[C@H](CC[C@]5(O)[C@]4(O)CC=C3C2)C(=O)C)OC(C)C1OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H17 compound treatment 148960.0 4240.0 0.13 138880.0 -8280.0 -0.22 -0.0591 -0.2345 3557608 ACon1_000795 COC(=O)C1=CCC[C@@H]2[C@@]3(CC(OC3=O)c4ccoc4)[C@H](C)CC[C@]21C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H18 compound treatment 120800.0 -23900.0 -0.74 123000.0 -24200.0 -0.63 -0.9678 -0.9966 3558016 ACon1_000796 COc1c(oc2c(OC)c(O)cc(O)c2c1=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H19 mock treatment 139480.0 -5240.0 -0.16 154360.0 7200.0 0.19 0.0176 0.071 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H20 mock treatment 135680.0 -9040.0 -0.28 141440.0 -5720.0 -0.15 -0.303 -0.956 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H21 compound treatment 147720.0 3000.0 0.09 146080.0 -1080.0 -0.03 0.046 0.4737 3558356 ACon1_000797 CCC1C2O[C@H]3OC=C([C@H]4C=C[C@]2(OC1=O)[C@@H]34)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H22 compound treatment 145280.0 562.0 0.02 148240.0 1080.0 0.03 0.0322 0.9732 3558238 ACon1_000798 CC(O)(C=C)C(O)CC1C(=C)CCC2C(C)(CCCC12C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H23 compound treatment 126960.0 -17800.0 -0.55 155880.0 8720.0 0.23 -0.2288 -0.3844 3553600 ACon1_000799 CC(C)C1NC(=O)/C(=C/c2nc[nH]c2C(C)(C)C=C)/NC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 H24 compound treatment 82840.0 -61900.0 -1.92 93080.0 -54100.0 -1.41 -2.3492 -0.9883 3558108 ACon1_000800 CC1(C)[C@H]2C[C@@H]1C(=CC2)CO[C@@H]3O[C@H](CO[C@@H]4O[C@@H](CO)[C@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I01 compound treatment 116880.0 -27800.0 -0.86 100440.0 -46700.0 -1.21 -1.4682 -0.986 3558341 ACon1_000801 COC(=O)C1=C[C@@H](O)[C@@H](O)[C@@H](C1)O[C@@H]2O[C@H](COC(=O)/C=C/c3ccccc3)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I02 compound treatment 159200.0 14500.0 0.45 136880.0 -10300.0 -0.27 0.1285 0.2461 3558497 ACon1_000802 CC1=CC(=O)C2=C(C)C[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]4[C@H](OC(=O)C4=C)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I03 compound treatment 101040.0 -43700.0 -1.35 79040.0 -68100.0 -1.77 -2.2084 -0.9912 3558461 ACon1_000803 CC(CC[C@@]1(C)[C@H](C)CC[C@]2(C)C1CCC=C2COC(=O)C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I04 compound treatment 169200.0 24500.0 0.76 146880.0 -276.0 -0.01 0.5313 0.7004 3558501 ACon1_000804 CC(OC1OC(CO)C(O)C(O)C1O)C2C(O)CC3C4CCC5=CC(=O)CCC5(C)C4CCC23C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I05 mock treatment 155760.0 11000.0 0.34 150160.0 3000.0 0.08 0.2971 0.8467 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I06 mock treatment 142400.0 -2320.0 -0.07 148200.0 1040.0 0.03 -0.0316 -0.4116 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I07 compound treatment 140320.0 -4400.0 -0.14 176600.0 29400.0 0.77 0.4446 0.5722 3557857 ACon1_000805 COc1c2ccoc2c(OC)c3oc(CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(=O)c13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I08 compound treatment 156360.0 11600.0 0.36 164560.0 17400.0 0.45 0.5748 0.9937 3614493 ACon1_000806 COc1cc(O)c2c(=O)cc(oc2c1OC)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I09 compound treatment 147560.0 2840.0 0.09 153200.0 6040.0 0.16 0.1733 0.9626 3557926 ACon1_000807 CC1(C)C2CC(OC3OC(CO)C(O)C(O)C3O)C1(C)CC2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I10 compound treatment 127760.0 -17000.0 -0.53 146440.0 -716.0 -0.02 -0.3847 -0.7317 3558796 ACon1_000808 COc1cc(O)c(OC)c2OC(CC(=O)c12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I11 compound treatment 116320.0 -28400.0 -0.88 122320.0 -24800.0 -0.65 -1.0785 -0.9884 3558071 ACon1_000809 CC(C)CC(=O)O[C@@H]1OC=C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)/C=C/c3ccc(O)cc3)[C@H]4CCC(CO)[C@H]41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I12 compound treatment 166960.0 22200.0 0.69 164280.0 17100.0 0.44 0.8019 0.9776 2084711 ACon1_000810 CC(=CCc1c(O)ccc2ccc(=O)oc12)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I13 compound treatment 160920.0 16200.0 0.5 143360.0 -3800.0 -0.1 0.2852 0.5575 3558138 ACon1_000811 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(COC(=O)/C=C/c5ccc(O)cc5)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I14 compound treatment 167640.0 22900.0 0.71 160080.0 12900.0 0.34 0.7397 0.9415 3555622 ACon1_000812 O[C@H]1[C@@H](O)[C@H](OC(=O)Cc2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1OC(=O)Cc3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I15 compound treatment 164320.0 19600.0 0.61 146640.0 -516.0 -0.01 0.42 0.6913 3558149 ACon1_000813 OC[C@H]1O[C@@H](OC/C/2=C\[C@H]3OC(=O)C(=C)[C@@H]3[C@@H]4C/C(=C\CC2)/C(=O)O4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I16 compound treatment 149360.0 4640.0 0.14 141280.0 -5880.0 -0.15 -0.0062 -0.0298 3557723 ACon1_000814 CC1[C@@H]2CC/C(=C/CC/C(=C/[C@H]2OC1=O)/C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I17 compound treatment 151920.0 7200.0 0.22 138360.0 -8800.0 -0.23 -0.0038 -0.0119 3558279 ACon1_000815 C/C(=C\CCC(O)C(C)(C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)/CCC(C)(O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I18 compound treatment 148920.0 4200.0 0.13 122680.0 -24500.0 -0.64 -0.3576 -0.5509 3558214 ACon1_000816 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/[C@H](C/C=C(\C)/C[C@@H]2O)OC(=O)C(=C)[C@@H]3CCC(=C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=C)[C@@H]4C3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I19 compound treatment 186560.0 41800.0 1.3 157200.0 10000.0 0.26 1.1013 0.8327 3614503 ACon1_000817 CC1OC(=O)CC2C(=CC3(O)CC(C)(C)CC213)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I20 compound treatment 104800.0 -39900.0 -1.24 106120.0 -41000.0 -1.07 -1.6285 -0.9973 1072848 ACon1_000818 COc1c(oc2cc(O)cc(O)c2c1=O)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I21 mock treatment 159160.0 14400.0 0.45 159160.0 12000.0 0.31 0.537 0.9844 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I22 mock treatment 161240.0 16500.0 0.51 155840.0 8680.0 0.23 0.5215 0.9322 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I23 compound treatment 118680.0 -26000.0 -0.81 80520.0 -66600.0 -1.73 -1.7947 -0.9396 3554830 ACon1_000819 COc1cc(c(OC)c2oc3cc(O)c(O)cc3c12)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 I24 compound treatment 109280.0 -35400.0 -1.1 114640.0 -32500.0 -0.84 -1.3738 -0.9916 3558502 ACon1_000820 COc1cc2OCOc2cc1c3coc4cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)ccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J01 compound treatment 9240.0 -135000.0 -4.2 7440.0 -140000.0 -3.63 -5.5352 -0.9974 3553370 ACon1_000821 CC(=O)OC[C@@]12C[C@H](O)C(=C[C@H]2O[C@@H]3[C@H](O)[C@@H](OC(=O)C)[C@@]1(C)[C@@]43CO4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J02 compound treatment 151040.0 6320.0 0.2 114280.0 -32900.0 -0.85 -0.4655 -0.5312 3558605 ACon1_000822 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5[C@H](O)C[C@]43C)C2C1)C(=O)OC6OCC(OC7OCC(O)C(O)C7O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J03 compound treatment 149720.0 5000.0 0.15 144360.0 -2800.0 -0.07 0.0582 0.3402 3558664 ACon1_000823 CC(C(=O)O)[C@@]12CC[C@H](C)[C@H](CCC(=O)O)C(C)C2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J04 compound treatment 143920.0 -798.0 -0.02 140760.0 -6400.0 -0.17 -0.135 -0.8035 3559918 ACon1_000824 CC(=CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)[C@H](O)[C@H](Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J05 mock treatment 194600.0 49900.0 1.55 165480.0 18300.0 0.48 1.4295 0.8839 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J06 mock treatment 162200.0 17500.0 0.54 151880.0 4720.0 0.12 0.4698 0.8459 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J07 compound treatment 157880.0 13200.0 0.41 142640.0 -4520.0 -0.12 0.2054 0.484 3558736 ACon1_000825 CC1CCC2(C)C(CCC=C2C(=O)O)C1(C)CCC3=CC(O)OC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J08 compound treatment 161240.0 16500.0 0.51 141840.0 -5320.0 -0.14 0.2643 0.4985 3558372 ACon1_000826 CC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]1[C@H]23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J09 compound treatment 152200.0 7480.0 0.23 168600.0 21400.0 0.56 0.5579 0.9245 3558673 ACon1_000827 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c3c(=O)cc(oc3c1OC)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J10 compound treatment 154640.0 9920.0 0.31 147920.0 764.0 0.02 0.2314 0.7512 3553747 ACon1_000828 CC(O)C(C)CC/C=C(\C)/C(O)C/C=C(\C)/C=C/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J11 compound treatment 151440.0 6720.0 0.21 150240.0 3080.0 0.08 0.2039 0.9139 3614508 ACon1_000829 COc1cc(oc(=O)c1C)/C(=C/C(C)CCCC(=O)O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J12 compound treatment 15360.0 -129000.0 -4.01 14040.0 -133000.0 -3.46 -5.2798 -0.9973 3554483 ACon1_000830 CN1C(=O)C23CC4=CC=CC(OC(=O)C)C4N3C(=O)C1(CO)SS2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J13 compound treatment 164720.0 20000.0 0.62 161040.0 13900.0 0.36 0.6933 0.9668 3559771 ACon1_000831 COc1ccc(/C=C/2\Oc3cc(O)cc(O)c3C2=O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J14 compound treatment 157120.0 12400.0 0.38 157560.0 10400.0 0.27 0.4629 0.9852 3557886 ACon1_000832 COc1cc(CCCO)cc2C(CO)C(Oc21)c3ccc(OC)c(OC4OC(CO)C(O)C(O)C4O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J15 compound treatment 134040.0 -10700.0 -0.33 131360.0 -15800.0 -0.41 -0.5242 -0.9943 3559738 ACon1_000833 COC1=CC(C)c2c(C)c3c(C)coc3c(OC)c2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J16 compound treatment 15560.0 -129000.0 -4.0 12880.0 -134000.0 -3.49 -5.2968 -0.9977 3558192 ACon1_000834 C[C@H]1[C@H]2[C@H](CC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]6O)O[C@@]91CCC(C)CO9 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J17 compound treatment 165120.0 20400.0 0.63 161120.0 14000.0 0.36 0.7036 0.9653 3558487 ACon1_000835 CC1=C2[C@H](O)C(=O)O[C@H](c3ccoc3)[C@]2(C)CC[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J18 compound treatment 138280.0 -6440.0 -0.2 128080.0 -19100.0 -0.5 -0.4915 -0.92 3553097 ACon1_000836 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/[C@H](C/C=C(\C)/C[C@@H]2O)OC(=O)C(=C)[C@@H]3CCC(=C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO[C@H]6OC[C@](O)(CO)[C@H]6O)[C@@H](O)[C@H](O)[C@H]5O)C(=C)[C@@H]4C3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J19 compound treatment 156520.0 11800.0 0.37 153520.0 6360.0 0.17 0.3755 0.9356 3614518 ACon1_000837 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=CC(=O)C(C)(O)C(O)C2CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J20 compound treatment 13480.0 -131000.0 -4.07 11680.0 -135000.0 -3.52 -5.3644 -0.9974 3558583 ACon1_000838 C/C=C(/C)\C(=O)OC1C(=C)C2CC31CCC4[C@](C)(CCC[C@]4(C)C3CC2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J21 mock treatment 174080.0 29400.0 0.91 151640.0 4480.0 0.12 0.7257 0.7912 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J22 mock treatment 150640.0 5920.0 0.18 145480.0 -1680.0 -0.04 0.099 0.5248 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J23 compound treatment 34400.0 -110000.0 -3.42 40920.0 -106000.0 -2.76 -4.3688 -0.9944 3558317 ACon1_000839 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@H]3CC[C@]4(C)C5CC[C@]6(C)[C@H](CC[C@]6(O)[C@@H]5CCC4=C3)c7ccc(=O)oc7)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 J24 compound treatment 32480.0 -112000.0 -3.48 17120.0 -130000.0 -3.38 -4.8482 -0.9999 3614523 ACon1_000840 COC1C(=O)Nc2ccc3C=CC(C)(CCC=C(C)C)Oc3c2C1(O)c4ccc(OC)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K01 compound treatment 122440.0 -22300.0 -0.69 92360.0 -54800.0 -1.42 -1.4948 -0.9448 3558362 ACon1_000841 CC(=CCC/C(=C/C(O)C/C(=C/C(O)CC(C)(O)C=C)/C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K02 compound treatment 91240.0 -53500.0 -1.66 80400.0 -66800.0 -1.73 -2.3981 -0.9997 3558452 ACon1_000842 COc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K03 compound treatment 163960.0 19200.0 0.6 142400.0 -4760.0 -0.12 0.3342 0.5489 3558557 ACon1_000843 C/C(=C/COc1c(OC2OC(CO)C(O)C(O)C2O)ccc3ccc(=O)oc13)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K04 compound treatment 171520.0 26800.0 0.83 149200.0 2040.0 0.05 0.6248 0.7508 3558485 ACon1_000844 CC1[C@H]2C[C@@H]3[C@@H](CC[C@@]3(C)O)C(=C)CC2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K05 compound treatment 129560.0 -15200.0 -0.47 122320.0 -24800.0 -0.65 -0.7884 -0.9878 3557306 ACon1_000845 CC1=CC2O[C@@H]3[C@H](O)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@](C)(C53CO5)[C@@]2(CO)CC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K06 compound treatment 153520.0 8800.0 0.27 160040.0 12900.0 0.33 0.4296 0.9948 3614529 ACon1_000846 COc1ccc2C(=O)[C@]3(O)[C@@H](COc4cc5OCOc5cc43)Oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K07 mock treatment 150440.0 5720.0 0.18 150920.0 3760.0 0.1 0.1945 0.9607 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K08 mock treatment 143280.0 -1440.0 -0.04 145600.0 -1560.0 -0.04 -0.0601 -0.9988 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K09 compound treatment 161440.0 16700.0 0.52 145080.0 -2080.0 -0.05 0.3282 0.6301 3558035 ACon1_000847 CC1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C(CO)C(O)CC31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K10 compound treatment 14200.0 -131000.0 -4.04 12680.0 -134000.0 -3.49 -5.3302 -0.9973 3554481 ACon1_000848 CN1C(=O)[C@@]2(Cc3ccccc3)SSS[C@]1(CO)C(=O)N2C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K11 compound treatment 42320.0 -102000.0 -3.17 42120.0 -105000.0 -2.73 -4.1733 -0.9972 3614533 ACon1_000849 CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC(O)CC(O)CC(=O)O)C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K12 compound treatment 164640.0 19900.0 0.62 150120.0 2960.0 0.08 0.4909 0.7892 3558064 ACon1_000850 COc1cc2oc(cc(=O)c2c(O)c1OC)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K13 compound treatment 159560.0 14800.0 0.46 150560.0 3400.0 0.09 0.3877 0.8279 3558118 ACon1_000851 COc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(=O)O)cc(O)c3c(=O)cc(oc13)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K14 compound treatment 171680.0 27000.0 0.84 158760.0 11600.0 0.3 0.8039 0.9052 3557898 ACon1_000852 C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K15 mock treatment 144440.0 -278.0 -0.01 161440.0 14300.0 0.37 0.2563 0.6905 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K16 mock treatment 149560.0 4840.0 0.15 148920.0 1760.0 0.05 0.1385 0.8829 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K17 compound treatment 166400.0 21700.0 0.67 136600.0 -10600.0 -0.27 0.2811 0.3874 3558293 ACon1_000853 CC(C)c1cc2CCC3C(C)(CO)C[C@H](O)C[C@]3(C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K18 compound treatment 166080.0 21400.0 0.66 147040.0 -116.0 0.0 0.4659 0.7039 3558216 ACon1_000854 CC1=C2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3CC1)C(=CC2=O)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K19 compound treatment 145920.0 1200.0 0.04 85200.0 -62000.0 -1.61 -1.112 -0.6906 3553957 ACon1_000855 CC1C(OC(=O)C)C(OC(=O)C)C2=C(CCCC2(C)C)C1(C)CCC(C)(O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K20 compound treatment 145920.0 1200.0 0.04 153160.0 6000.0 0.16 0.1366 0.852 3558262 ACon1_000856 CC(C)C(O)(C(=O)C)C(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K21 compound treatment 143720.0 -998.0 -0.03 142120.0 -5040.0 -0.13 -0.1144 -0.8508 3558329 ACon1_000857 COc1c(O)cc(CCc2cc(O)cc(O)c2)cc1CC(O)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K22 compound treatment 141800.0 -2920.0 -0.09 113040.0 -34100.0 -0.89 -0.6907 -0.7752 3553545 ACon1_000858 CC(C)C(OC(=O)C)c1nc2ccccc2c(=O)n1C3CC4(OC3=O)C5N(O)C(C)(C)C(=O)N5c6ccccc64 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K23 mock treatment 156040.0 11300.0 0.35 151480.0 4320.0 0.11 0.3275 0.8891 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 K24 mock treatment 148760.0 4040.0 0.13 106240.0 -40900.0 -1.06 -0.6632 -0.6195 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L01 compound treatment 12040.0 -133000.0 -4.11 18480.0 -129000.0 -3.34 -5.271 -0.9947 3552660 ACon1_000859 C[C@@H]1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C)[C@@](C)(O)C(=O)[C@H]3O[C@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L02 compound treatment 10560.0 -134000.0 -4.16 13080.0 -134000.0 -3.48 -5.4026 -0.9961 3558654 ACon1_000860 COc1cc(/C=C/C(=O)CC(=O)\C=C\c2ccc(O)c(O)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L03 compound treatment 120960.0 -23800.0 -0.74 116320.0 -30800.0 -0.8 -1.0871 -0.9991 3558666 ACon1_000861 C[C@H]1CC[C@@H]2[C@@H](OC(=O)C2=C)C(=C)[C@H]1CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L04 compound treatment 149240.0 4520.0 0.14 124040.0 -23100.0 -0.6 -0.3256 -0.528 3559920 ACon1_000862 CC(=CCc1c(O[C@@H]2O[C@H](COC(=O)CC(=O)O)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)[C@H](O)[C@H](Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L05 compound treatment 147760.0 3040.0 0.09 115880.0 -31300.0 -0.81 -0.508 -0.6209 3558706 ACon1_000863 CC1C2C3=CCC4C5(C)C[C@@H](O)[C@H](O)C(C)(CO)C5CCC4(C)C3(C)CCC2(CCC1=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L06 compound treatment 13080.0 -132000.0 -4.08 10440.0 -137000.0 -3.55 -5.3959 -0.9976 3558287 ACon1_000864 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)O[C@@]%111CCC(C)CO%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L07 mock treatment 158720.0 14000.0 0.43 150200.0 3040.0 0.08 0.3627 0.8225 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L08 mock treatment 173040.0 28300.0 0.88 151720.0 4560.0 0.12 0.7044 0.7954 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L09 compound treatment 149960.0 5240.0 0.16 166800.0 19600.0 0.51 0.4758 0.8882 3552042 ACon1_000865 C/C=C(\C)/CC(/C=C(\C)/C(O)C(C)/C=C(\C)/C(O)C(C)/C=C/C(O)C/C=C/C(O)C(O)C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L10 compound treatment 168840.0 24100.0 0.75 161360.0 14200.0 0.37 0.7895 0.9471 3558492 ACon1_000866 COc1cc(CC2COC(C2COC(=O)C)c3ccc(O)c(OC)c3)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L11 compound treatment 89160.0 -55600.0 -1.72 41040.0 -106000.0 -2.76 -3.1669 -0.9743 3614544 ACon1_000867 CC1CCC/C=C/2\C3C(OC(=C3C(=O)O1)\C=C\C=C\C=C\C(=O)O)C=CC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L12 compound treatment 155520.0 10800.0 0.33 156240.0 9080.0 0.24 0.4036 0.9854 3554712 ACon1_000868 COC(=O)c1cc(OC)cc(O)c1C(=O)c2c(O)cc(C)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L13 compound treatment 186400.0 41700.0 1.29 155040.0 7880.0 0.2 1.0581 0.8092 3559773 ACon1_000869 COc1cc(/C=C/2\Oc3cc(O)cc(O)c3C2=O)cc(OC)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L14 compound treatment 112720.0 -32000.0 -0.99 120360.0 -26800.0 -0.7 -1.1934 -0.985 3558463 ACon1_000870 CC(C)c1cc2C3OC(=O)[C@@]4(CCCC(C)(C)C4[C@H]3O)c2c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L15 mock treatment 177720.0 33000.0 1.02 142200.0 -4960.0 -0.13 0.632 0.6132 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L16 mock treatment 157000.0 12300.0 0.38 146560.0 -596.0 -0.02 0.2581 0.6778 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L17 compound treatment 176880.0 32200.0 1.0 148280.0 1120.0 0.03 0.7253 0.7275 3555854 ACon1_000871 OC(=O)CCC1OC(=O)C(=C1c2ccccc2)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L18 compound treatment 159520.0 14800.0 0.46 132720.0 -14400.0 -0.38 0.0591 0.0997 3553101 ACon1_000872 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/[C@H](C/C=C(\C)/C[C@@H]2O)OC(=O)C(=C)[C@@H]3CCC(=C)[C@@H]4C[C@H](O[C@@H]5O[C@H](COC(=O)CC(=O)O)[C@@H](O)[C@H](O)[C@H]5O)C(=C)[C@@H]4C3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L19 compound treatment 157880.0 13200.0 0.41 170720.0 23600.0 0.61 0.7213 0.9805 3614554 ACon1_000873 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=C(Cl)C(=O)C(C)(O)C(O)C2=CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L20 compound treatment 15320.0 -129000.0 -4.01 11080.0 -136000.0 -3.54 -5.3351 -0.998 3558638 ACon1_000874 C/C=C(/C)\C(=O)O[C@H]\1C[C@@H]2[C@H](OC(=O)C2=C)[C@@H]3O[C@]3(C)CC/C=C1\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L21 compound treatment 158800.0 14100.0 0.44 156560.0 9400.0 0.24 0.4813 0.9625 3554505 ACon1_000875 CO[C@@H]1C[C@]2(CC=C)[C@@H](C)[C@@H](OC2=C(OC)C1=O)c3cc4OCOc4c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L22 compound treatment 141040.0 -3680.0 -0.11 138080.0 -9080.0 -0.24 -0.2473 -0.9443 3558750 ACon1_000876 CC(=CCCC(=CCCC(=CC1C(O)C=C(C)C1=O)C)C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L23 mock treatment 158720.0 14000.0 0.43 155520.0 8360.0 0.22 0.4604 0.9489 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 L24 mock treatment 128120.0 -16600.0 -0.51 127840.0 -19300.0 -0.5 -0.7185 -0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M01 compound treatment 108440.0 -36300.0 -1.12 96480.0 -50700.0 -1.32 -1.7259 -0.9969 2112282 ACon1_000877 CC1=C2C(=O)O[C@@H](c3ccoc3)[C@]2(C)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M02 compound treatment 138640.0 -6080.0 -0.19 126520.0 -20600.0 -0.54 -0.5123 -0.9015 3558453 ACon1_000878 COc1cc(ccc1O)c2cc(=O)c3c(O)c(OC)c(OC)c(O)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M03 compound treatment 172720.0 28000.0 0.87 127120.0 -20000.0 -0.52 0.2454 0.2425 3558587 ACon1_000879 COc1cc(C[C@@H]2COC([C@@H]2CO)c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)ccc1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M04 compound treatment 143280.0 -1440.0 -0.04 121440.0 -25700.0 -0.67 -0.504 -0.7526 3554680 ACon1_000880 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/[C@@H]1CC(=O)OCC(C3CCC(C)C3C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M05 compound treatment 15880.0 -129000.0 -3.99 14200.0 -133000.0 -3.45 -5.2655 -0.9974 3553941 ACon1_000881 CC1=CC2O[C@@H]3[C@H](O)[C@@H](O)[C@@](C)(C43CO4)[C@@]2(CO)CC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M06 compound treatment 23640.0 -121000.0 -3.75 22080.0 -125000.0 -3.25 -4.9507 -0.9974 3559292 ACon1_000882 CO[C@H]1C[C@@H](Oc2c(CC=C(C)C)c(OC)cc(OC)c12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M07 compound treatment 136080.0 -8640.0 -0.27 125400.0 -21800.0 -0.57 -0.589 -0.9417 3557952 ACon1_000883 COc1ccc(C2COc3cc(O)ccc3C2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M08 compound treatment 146800.0 2080.0 0.06 121360.0 -25800.0 -0.67 -0.4283 -0.6361 3554197 ACon1_000884 CCC1(C)C(O)C2=COC(=C(C)C2=CC1=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M09 mock treatment 151040.0 6320.0 0.2 127320.0 -19800.0 -0.52 -0.2259 -0.4098 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M10 mock treatment 152880.0 8160.0 0.25 143680.0 -3480.0 -0.09 0.115 0.4281 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M11 compound treatment 160040.0 15300.0 0.47 144520.0 -2640.0 -0.07 0.2873 0.5989 3553758 ACon1_000885 CC(O)CCCC1Cc2cccc(O)c2C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M12 compound treatment 139360.0 -5360.0 -0.17 132120.0 -15000.0 -0.39 -0.3936 -0.9273 3554988 ACon1_000886 COc1cc(O)c2c(=O)oc3c(O)c(OC)cc(C)c3c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M13 mock treatment 139640.0 -5080.0 -0.16 143040.0 -4120.0 -0.11 -0.1869 -0.9823 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M14 mock treatment 154160.0 9440.0 0.29 141400.0 -5760.0 -0.15 0.1011 0.3078 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M15 compound treatment 149200.0 4480.0 0.14 135200.0 -12000.0 -0.31 -0.1215 -0.357 3614568 ACon1_000887 CC1OC(OC(=O)C2=CC3CC(C)(C)CC34C2CC(=O)OC4C)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M16 compound treatment 149400.0 4680.0 0.15 130600.0 -16600.0 -0.43 -0.2016 -0.4441 3557904 ACon1_000888 Cc1c(O[C@@H]2O[C@H](COC(=O)CC(C)(O)CC(=O)O)C[C@H](O)[C@H]2O)occc1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M17 compound treatment 142240.0 -2480.0 -0.08 141360.0 -5800.0 -0.15 -0.1608 -0.9511 3554555 ACon1_000889 COC(=O)[C@]1(C)CCC[C@@]2(C)C1CC(OC(=O)C)C3=C2CC(OC(=O)C)[C@](C)(C=C)C3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M18 compound treatment 93240.0 -51500.0 -1.6 70920.0 -76200.0 -1.98 -2.5285 -0.9942 3557955 ACon1_000890 CC(O)CCCCCCCCCC(Cc1cc(O)cc(O)c1)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M19 compound treatment 172680.0 28000.0 0.87 146400.0 -756.0 -0.02 0.5987 0.6909 3558411 ACon1_000891 C[C@]1(O)CC[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](COC(=O)c4ccc(O)cc4)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M20 compound treatment 165640.0 20900.0 0.65 131080.0 -16100.0 -0.42 0.163 0.2114 3554267 ACon1_000892 CCCCCC(O)C1OC(=O)CCC(O)C(O)/C=C/C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M21 compound treatment 156680.0 12000.0 0.37 145240.0 -1920.0 -0.05 0.2269 0.6067 3558351 ACon1_000893 Cc1cc(O)c2C(=O)c3c(O)cc(OC4OC(COC(=O)CC(=O)O)C(O)C(O)C4O)cc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M22 compound treatment 156800.0 12100.0 0.37 129920.0 -17200.0 -0.45 -0.052 -0.089 3552748 ACon1_000894 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(=O)C)[C@H](O[C@@H]3[C@@H](O)[C@H](C)O[C@@H](Oc4ccc5c(=O)c(coc5c4)c6ccc(O)cc6)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M23 compound treatment 118560.0 -26200.0 -0.81 114320.0 -32800.0 -0.85 -1.1764 -0.9997 3558422 ACon1_000895 CC(=O)OC1C(=C)C2C[C@]31CCC4[C@@](C)(CCC[C@@]4(C)C3CC2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 M24 compound treatment 127240.0 -17500.0 -0.54 109560.0 -37600.0 -0.98 -1.0737 -0.9613 3558504 ACon1_000896 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H]3[C@@H](C[C@H](O)C3=C)C(=C)C[C@@H]2O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N01 compound treatment 122360.0 -22400.0 -0.69 117240.0 -29900.0 -0.78 -1.0395 -0.9984 3555900 ACon1_000897 OC[C@H]1O[C@@H](Oc2cc(O)cc3oc(=O)cc(c4ccc(O)c(O)c4)c23)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N02 compound treatment 178640.0 33900.0 1.05 132240.0 -14900.0 -0.39 0.4692 0.4188 3614577 ACon1_000898 CC1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(OC6OCC(O)C(O)C6O)C(C)(C)C5CCC43C)C2C1O)C(=O)OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N03 compound treatment 172560.0 27800.0 0.86 111160.0 -36000.0 -0.94 -0.0513 -0.0403 3558675 ACon1_000899 COc1ccccc1c2cc(=O)c3c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(OC)c(OC)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N04 compound treatment 145680.0 962.0 0.03 110400.0 -36800.0 -0.96 -0.6542 -0.6847 3559922 ACon1_000900 CC(=CCc1c(O[C@@H]2O[C@H](COC(=O)CC(=O)O)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)C[C@H](Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N05 compound treatment 156640.0 11900.0 0.37 137560.0 -9600.0 -0.25 0.0849 0.1905 3614580 ACon1_000901 CC1=CCC2C(C)(CO)CCCC2(C)C1CC34OC4C(O)C(=CC3O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N06 compound treatment 12520.0 -132000.0 -4.1 8920.0 -138000.0 -3.59 -5.4361 -0.9979 3558417 ACon1_000902 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](OC(=O)C)[C@@H]2OC(=O)\C=C\c7ccc(OC)cc7)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N07 compound treatment 145240.0 522.0 0.02 123680.0 -23500.0 -0.61 -0.4199 -0.6881 3557311 ACon1_000903 CC(C)CCC(O)C1CC(CO)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N08 compound treatment 152520.0 7800.0 0.24 137760.0 -9400.0 -0.24 -0.0017 -0.0049 3558683 ACon1_000904 CC(C)(O)CCC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(CC(OC5OC(CO)C(O)C(O)C5O)C(O)C4(C)C)C3(C)CCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N09 mock treatment 144720.0 1.94 0.0 145520.0 -1640.0 -0.04 -0.03 -0.7061 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N10 mock treatment 148440.0 3720.0 0.12 144280.0 -2880.0 -0.07 0.0287 0.209 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N11 compound treatment 128720.0 -16000.0 -0.5 110520.0 -36600.0 -0.95 -1.0236 -0.9538 3614587 ACon1_000905 CC1CCC/C=C/C/C=C\C(OC(=O)/C=C\C=C\C=C\C(=O)O)/C=C/C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N12 compound treatment 125480.0 -19200.0 -0.6 153880.0 6720.0 0.17 -0.2979 -0.4797 3558740 ACon1_000906 COc1ccc(cc1)c2oc3cc(OC)cc(O)c3c(=O)c2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N13 mock treatment 156440.0 11700.0 0.36 140880.0 -6280.0 -0.16 0.1415 0.3555 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N14 mock treatment 145160.0 442.0 0.01 152880.0 5720.0 0.15 0.1149 0.769 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N15 compound treatment 167520.0 22800.0 0.71 108920.0 -38200.0 -0.99 -0.2029 -0.1664 3559368 ACon1_000907 CC(=C)C1CCC2(CCC3(C)C(CCC4C5(C)C(C=O)C(O)C(C)(CO)C5CCC43C)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N16 compound treatment 53840.0 -90900.0 -2.82 40400.0 -107000.0 -2.77 -3.9525 -1.0 3552752 ACon1_000908 C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C)C4C[C@@H](O)[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CCC3=C2)c6ccc(=O)oc6)[C@H](O)[C@H](O)[C@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N17 compound treatment 152120.0 7400.0 0.23 136720.0 -10400.0 -0.27 -0.0296 -0.0832 3553640 ACon1_000909 CC(C)Cc1cnc(CCC(=O)N)c(=O)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N18 compound treatment 159440.0 14700.0 0.46 111600.0 -35600.0 -0.92 -0.3307 -0.321 3558595 ACon1_000910 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O[C@H]7OC[C@](O)(CO)[C@H]7O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N19 compound treatment 128000.0 -16700.0 -0.52 82960.0 -64200.0 -1.67 -1.5457 -0.885 3614597 ACon1_000911 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=C(Cl)C(=O)C(C)(O)C(OC(=O)C)C2CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N20 compound treatment 71360.0 -73400.0 -2.27 63920.0 -83200.0 -2.16 -3.1365 -0.9997 3558712 ACon1_000912 CC(C)C(=O)OC/C(=C/CCC(=C)C1CC=C(COC(=O)C(C)C)C(O)C1)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N21 compound treatment 146120.0 1400.0 0.04 126480.0 -20700.0 -0.54 -0.3492 -0.6478 3614600 ACon1_000913 CC(CCO)/C=C(\C)/C=C/C1=CC2=CC(=O)C(C)(O)C(O)C2=CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N22 compound treatment 38000.0 -107000.0 -3.31 21240.0 -126000.0 -3.27 -4.6515 -1.0 3559260 ACon1_000914 CC1OC(OC2C(O)C(CO)OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)OC8OCC(OC9OCC(O)C(O)C9O)C(O)C8O)C3(C)C)C2O)C(O)C(OC%10OCC(O)(CO)C%10O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N23 compound treatment 151880.0 7160.0 0.22 134000.0 -13200.0 -0.34 -0.0848 -0.2081 3558089 ACon1_000915 COC1CC(O[C@H]2CC[C@]3(C)C4[C@H](O)[C@@H](O)[C@]5(C)[C@H](CC[C@]5(O)C4CC=C3C2)[C@H](C)O)OC(C)C1OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 N24 compound treatment 138560.0 -6160.0 -0.19 132760.0 -14400.0 -0.37 -0.3994 -0.9512 3557301 ACon1_000916 CC(OC(=O)c1cccc(O)c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O01 compound treatment 102600.0 -42100.0 -1.31 129080.0 -18100.0 -0.47 -1.2549 -0.9048 3557296 ACon1_000917 C[C@@H]1Cc2c(O)c(O)cc(O)c2C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O02 compound treatment 74200.0 -70500.0 -2.18 67160.0 -80000.0 -2.08 -3.0147 -0.9997 3497202 ACon1_000918 CC(=CCO)CCC1C(C)(O)CCC2C(C)(C)CCCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O03 compound treatment 167440.0 22700.0 0.7 123200.0 -24000.0 -0.62 0.0577 0.0614 3558589 ACon1_000919 CSC(=O)OCC1=C[C@H](O)[C@H]2[C@@H]1[C@H](OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O04 compound treatment 159840.0 15100.0 0.47 137400.0 -9760.0 -0.25 0.1521 0.2855 3558219 ACon1_000920 C[C@@H]1CC[C@]2(C)[C@H](CC[C@@H](O)[C@]2(C)O)[C@@]1(C)CC/C(=C/CO)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O05 compound treatment 164880.0 20200.0 0.62 117800.0 -29400.0 -0.76 -0.0976 -0.099 1045397 ACon1_000921 COc1ccc(cc1OC)c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O06 compound treatment 127160.0 -17600.0 -0.54 109440.0 -37700.0 -0.98 -1.0776 -0.9614 1046376 ACon1_000922 COc1c(O)c2c(=O)cc(oc2c(OC)c1OC)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O07 compound treatment 156320.0 11600.0 0.36 106720.0 -40400.0 -1.05 -0.4887 -0.4401 3557981 ACon1_000923 OC[C@H]1O[C@@H](OC2OC=C(C3CCC(=C)C32)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O08 compound treatment 149920.0 5200.0 0.16 99640.0 -47500.0 -1.23 -0.759 -0.6096 3554706 ACon1_000924 COC(=O)c1cc(O)cc(OC)c1C(=O)c2c(O)cc(C)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O09 compound treatment 142160.0 -2560.0 -0.08 89200.0 -58000.0 -1.51 -1.1208 -0.7433 3551984 ACon1_000925 C/C(=C\OC(=O)/C=C/c1ccc(O)cc1)/C(O)C2OC(=O)/C(=C\COC3OC(CO)C(O)C(O)C3O)/C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O10 compound treatment 128800.0 -15900.0 -0.49 104800.0 -42400.0 -1.1 -1.1269 -0.9345 3558809 ACon1_000926 CC(C)(O)[C@@H]1Cc2cc3cc(c(=O)oc3cc2O1)C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O11 mock treatment 155360.0 10600.0 0.33 146320.0 -836.0 -0.02 0.2178 0.6591 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O12 mock treatment 163240.0 18500.0 0.57 144400.0 -2760.0 -0.07 0.3552 0.6141 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O13 compound treatment 155400.0 10700.0 0.33 151440.0 4280.0 0.11 0.3127 0.8956 3553125 ACon1_000927 C[C@H]1CC(O)C23COC(=O)[C@@H]3CCC[C@@H]2[C@]41C[C@H](OC4=O)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O14 compound treatment 155440.0 10700.0 0.33 149160.0 2000.0 0.05 0.2717 0.8081 3557917 ACon1_000928 C[C@]1(C[C@]2(O)O[C@@H]3O1)[C@]4(C[C@@H]2C34COC(=O)c5ccccc5)O[C@@H]6O[C@H](COC(=O)c7ccccc7)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O15 compound treatment 188720.0 44000.0 1.36 132720.0 -14400.0 -0.38 0.6988 0.4942 3555917 ACon1_000929 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3oc4c(O)c(O)ccc4c(=O)c3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O16 compound treatment 257240.0 113000.0 3.49 108480.0 -38700.0 -1.0 1.7547 0.4836 3557831 ACon1_000930 CC1OC(OC2C(O)C(O)C(Oc3cc(O)c4c(=O)c(coc4c3)c5ccc(O)c(O)c5)OC2CO)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O17 compound treatment 181600.0 36900.0 1.14 136360.0 -10800.0 -0.28 0.6097 0.5182 3557287 ACon1_000931 CCCC1CCC(C(=C)C(=O)O)C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O18 compound treatment 178600.0 33900.0 1.05 123520.0 -23600.0 -0.61 0.3081 0.2533 3558352 ACon1_000932 C[C@]12C[C@H](OC(=O)C(=C)C(O)CO)[C@@H]3[C@H](OC(=O)C3=C)C2C(CC[C@H]1O)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O19 compound treatment 184800.0 40100.0 1.24 170320.0 23200.0 0.6 1.3038 0.9447 1062453 ACon1_000933 COc1c(O)cc2oc(cc(=O)c2c1O)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O20 compound treatment 150920.0 6200.0 0.19 125720.0 -21400.0 -0.56 -0.2579 -0.4378 3557279 ACon1_000934 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3cc(OC)cc(OC)c3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O21 compound treatment 168400.0 23700.0 0.73 151600.0 4440.0 0.12 0.6005 0.8084 3558330 ACon1_000935 CC(C)(O)C1Cc2cc(CCc3cc(O)cc(O)c3)ccc2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O22 compound treatment 121280.0 -23400.0 -0.73 89560.0 -57600.0 -1.5 -1.5717 -0.9449 3553357 ACon1_000936 CC(=O)OC/C/1=C/CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O23 compound treatment 143520.0 -1200.0 -0.04 123200.0 -24000.0 -0.62 -0.4664 -0.7479 3558425 ACon1_000937 COc1cc(/C=C/C(=O)OCc2ccccc2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 O24 compound treatment 150040.0 5320.0 0.16 121160.0 -26000.0 -0.68 -0.361 -0.5192 3555971 ACon1_000938 OCCC(CO)c1c(O)cc2C(=O)c3cc(O)cc(O)c3C(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P01 compound treatment 5360.0 -139000.0 -4.32 4760.0 -142000.0 -3.7 -5.6694 -0.997 3558656 ACon1_000939 C[C@@H]/1C[C@H]2OC(=O)C(=C)[C@@H]2[C@H](OC(=O)C(=C)C)[C@@H](OC(=O)C)[C@@](C)(O)C(=O)/C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P02 compound treatment 136840.0 -7880.0 -0.24 115960.0 -31200.0 -0.81 -0.7457 -0.881 3558684 ACon1_000940 CC(=O)OC1CC2(C)C3CC=C4C(CC(OC5OC(CO)C(O)C(O)C5O)C(O)C4(C)C)C3(C)CCC2(C)C1C(C)(O)C(=O)CCC(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P03 compound treatment 136400.0 -8320.0 -0.26 116120.0 -31000.0 -0.81 -0.7524 -0.8888 3558685 ACon1_000941 CC(=O)OC1CC2(C)C3CC=C4C(CC(O)C(O)C4(C)C)C3(C)CCC2(C)C1C(C)(O)C(=O)CCC(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P04 compound treatment 151400.0 6680.0 0.21 113160.0 -34000.0 -0.88 -0.4782 -0.5271 3554701 ACon1_000942 COC(=O)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P05 compound treatment 149080.0 4360.0 0.14 124960.0 -22200.0 -0.58 -0.3122 -0.5271 3614622 ACon1_000943 CC1=CCC2C(C)(CCCC2(C)C1CC34OC4C(O)C(=C)C(O)C3O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P06 compound treatment 153480.0 8760.0 0.27 122640.0 -24500.0 -0.64 -0.2584 -0.3733 3558470 ACon1_000944 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@](C)(C5CC[C@]43C)C(=O)O)C2C1)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P07 compound treatment 66520.0 -78200.0 -2.42 58000.0 -89200.0 -2.32 -3.3513 -0.9997 3553189 ACon1_000945 CC(=CCC/C(=C\CC\C(=C\CC\C(=C\CO)\CO)\C)/C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P08 compound treatment 10960.0 -134000.0 -4.14 6840.0 -140000.0 -3.65 -5.5085 -0.998 3554753 ACon1_000946 COc1c(C)cc(C(=O)/C=C/c2ccccc2)c(O)c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P09 compound treatment 39200.0 -106000.0 -3.27 25920.0 -121000.0 -3.15 -4.5392 -0.9998 3552709 ACon1_000947 C[C@@H]1CCC(=O)[C@H](C)[C@@]1(C)/C=C/C(=C/Cc2c(O)c(Cl)c(C)c(C=O)c2O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P10 compound treatment 187760.0 43000.0 1.33 124560.0 -22600.0 -0.59 0.5279 0.3623 3558180 ACon1_000948 COc1cc(CCCO)cc2[C@@H](CO)[C@@H](Oc21)c3ccc(OC)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P11 mock treatment 153680.0 8960.0 0.28 130240.0 -16900.0 -0.44 -0.1144 -0.2201 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P12 mock treatment 162640.0 17900.0 0.56 152480.0 5320.0 0.14 0.4905 0.8571 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P13 compound treatment 151440.0 6720.0 0.21 141240.0 -5920.0 -0.15 0.0386 0.1491 3553333 ACon1_000949 CC(=O)O[C@@H]1C[C@](C)(C=C)C=C2[C@H](O)CC3C(C)(C)CC[C@@H](OC(=O)C)[C@]3(C)C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P14 compound treatment 165720.0 21000.0 0.65 115480.0 -31700.0 -0.82 -0.1218 -0.1161 3558552 ACon1_000950 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P15 compound treatment 159240.0 14500.0 0.45 134240.0 -12900.0 -0.34 0.0809 0.1441 3559386 ACon1_000951 CC(C)C(O)CC(C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P16 compound treatment 181040.0 36300.0 1.13 116800.0 -30400.0 -0.79 0.2381 0.1732 3558472 ACon1_000952 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@](C)(C5CC[C@]43C)C(=O)O)C2C1)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P17 compound treatment 193240.0 48500.0 1.5 127040.0 -20100.0 -0.52 0.6935 0.4357 3558567 ACon1_000953 CC1=C(CCC2=CC(=O)OC2O)[C@@]3(C)CCC[C@@]4(C)[C@@H]3C(OC4=O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P18 compound treatment 154640.0 9920.0 0.31 107120.0 -40000.0 -1.04 -0.5182 -0.4777 3558599 ACon1_000954 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)OC6OCC(O[C@H]7OC[C@](O)(CO)[C@H]7O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P19 compound treatment 160880.0 16200.0 0.5 119680.0 -27500.0 -0.71 -0.1507 -0.1728 3614634 ACon1_000955 CC(C)C1NC(=O)C(CC2(O)C3NC(Cc4ccccc4)C(=O)N3c5ccccc52)NC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P20 compound treatment 68080.0 -76600.0 -2.37 24200.0 -123000.0 -3.19 -3.9381 -0.9893 3551644 ACon1_000956 CC1Oc2c3C=CC(C)(C)Oc3c4c(cc(=O)oc4c2C(=O)C1C)c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P21 compound treatment 160360.0 15600.0 0.48 140240.0 -6920.0 -0.18 0.2156 0.4172 3554485 ACon1_000957 CN1C(=O)c2ccccc2NC(=O)[C@@]31O[C@@H]3c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P22 compound treatment 146400.0 1680.0 0.05 135880.0 -11300.0 -0.29 -0.1703 -0.5723 3554963 ACon1_000958 COc1cc(O)c(C(=O)O)c(c1)c2c(C)cc(oc2=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P23 compound treatment 87240.0 -57500.0 -1.78 71640.0 -75500.0 -1.96 -2.6467 -0.9988 3558309 ACon1_000959 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2292 P24 compound treatment 114360.0 -30400.0 -0.94 139280.0 -7880.0 -0.2 -0.8098 -0.8413 3557994 ACon1_000960 C[C@@H]1C[C@H](OC(=O)c2ccccc2)[C@H](OC(=O)C)[C@@]3(COC(=O)C)[C@H](C[C@@H]4[C@@H](OC(=O)c5ccccc5)[C@]13OC4(C)C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A01 compound treatment 5240.0 -154000.0 -4.76 5720.0 -144000.0 -3.75 -6.0203 -0.9931 3554483 ACon1_000961 CN1C(=O)C23CC4=CC=CC(OC(=O)C)C4N3C(=O)C1(CO)SS2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A02 compound treatment 114120.0 -44700.0 -1.39 115640.0 -34600.0 -0.9 -1.6153 -0.9779 3554004 ACon1_000962 CC1CC23OC3(/C=C(/C)\C(O)C(O)C4C(C(O)C(C)C2=O)C4(C)C)C1OC5OC(CO)C(O)C(O)C5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A03 compound treatment 124200.0 -34700.0 -1.07 151520.0 1310.0 0.03 -0.7353 -0.6843 3614644 ACon1_000963 CC(C)CC1NC(=O)C23C1C(=CC(O)C3/C=C/CCC4OC4(C)C(O)CC2=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A04 compound treatment 137760.0 -21100.0 -0.65 123480.0 -26700.0 -0.69 -0.9534 -0.9995 3558783 ACon1_000964 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A05 compound treatment 127240.0 -31600.0 -0.98 138200.0 -12000.0 -0.31 -0.9134 -0.8883 3553738 ACon1_000965 CC(O)(CC[C@H]1C(=C)CCC2[C@@](C)(CCC[C@]12C)C(=O)O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A06 compound treatment 6320.0 -153000.0 -4.73 6960.0 -143000.0 -3.72 -5.9739 -0.993 3558578 ACon1_000966 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A07 compound treatment 7200.0 -152000.0 -4.7 7520.0 -143000.0 -3.71 -5.9443 -0.9931 3558828 ACon1_000967 C/C/1=C\CCC2=CC(OC2=O)C(C)(C)/C=C\C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A08 compound treatment 20560.0 -138000.0 -4.29 21520.0 -129000.0 -3.34 -5.3944 -0.9925 3554998 ACon1_000968 COC1CC(O[C@H]2CC[C@@]3(C)[C@H](CCC45OC56CC=C(C7=CC(=O)OC7)[C@@]6(C)CCC43)C2)OC(C)C1O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A09 compound treatment 106520.0 -52300.0 -1.62 104240.0 -46000.0 -1.19 -1.9913 -0.9887 3558621 ACon1_000969 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(OC)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A10 compound treatment 20840.0 -138000.0 -4.28 15640.0 -135000.0 -3.5 -5.4963 -0.995 3558846 ACon1_000970 C/C(=C\CC[C@H](CO)[C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]4(C)CCC(=O)C(C)(C)C4CC3)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A11 compound treatment 96280.0 -62600.0 -1.94 118080.0 -32100.0 -0.83 -1.9614 -0.9291 3614654 ACon1_000971 CC(O)CC(=O)c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A12 compound treatment 118560.0 -40300.0 -1.25 119160.0 -31000.0 -0.81 -1.4534 -0.9776 3553484 ACon1_000972 CC(C)(OO)C1=C[C@]23CCC4[C@@](C)(CCC[C@]4(C)C3C[C@@H]1OO2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A13 mock treatment 154920.0 -3940.0 -0.12 141040.0 -9170.0 -0.24 -0.2548 -0.9519 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A14 mock treatment 152440.0 -6420.0 -0.2 136800.0 -13400.0 -0.35 -0.387 -0.9647 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A15 compound treatment 147200.0 -11700.0 -0.36 146360.0 -3850.0 -0.1 -0.3262 -0.87 3558823 ACon1_000973 CC1CCC2C1C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)OC4C5OC5(C)C6C(OC7OC(CO)C(O)C(O)C7O)OC=CC46O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A16 compound treatment 120000.0 -38900.0 -1.2 114200.0 -36000.0 -0.94 -1.513 -0.9922 3558930 ACon1_000974 OC1CCC(O)C(O)(C1O)C(=O)OCc2cc(O)ccc2OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A17 compound treatment 125080.0 -33800.0 -1.05 125920.0 -24300.0 -0.63 -1.1863 -0.9706 3558444 ACon1_000975 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A18 compound treatment 7720.0 -151000.0 -4.68 7800.0 -142000.0 -3.7 -5.9278 -0.9932 3558953 ACon1_000976 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A19 compound treatment 110360.0 -48500.0 -1.5 149640.0 -566.0 -0.01 -1.0731 -0.714 1113957 ACon1_000977 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A20 compound treatment 78320.0 -80500.0 -2.5 77600.0 -72600.0 -1.89 -3.0986 -0.9905 3558990 ACon1_000978 CCCCCC(CC(=O)CCc1ccc(O)c(OC)c1)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A21 compound treatment 4920.0 -154000.0 -4.77 5400.0 -145000.0 -3.76 -6.0332 -0.9931 3558623 ACon1_000979 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A22 compound treatment 5400.0 -153000.0 -4.75 5320.0 -145000.0 -3.76 -6.0242 -0.9933 3558955 ACon1_000980 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A23 compound treatment 149120.0 -9740.0 -0.3 145000.0 -5210.0 -0.14 -0.3091 -0.9344 3554993 ACon1_000981 COc1cc(O)cc(c1)C2=C(C)CC(O)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 A24 compound treatment 98200.0 -60700.0 -1.88 104320.0 -45900.0 -1.19 -2.1721 -0.9759 3552069 ACon1_000982 C/C=C/C=C/C(=O)C1=C(O)[C@]2(C)C3C(=C(O)C4(C)C1[C@]5(C)O[C@@]4(O)[C@@]3(C)O[C@@]52O)C(=O)\C=C\C=C\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B01 compound treatment 152840.0 -6020.0 -0.19 156120.0 5910.0 0.15 -0.0233 -0.0963 3558240 ACon1_000983 C[C@@H]1O[C@@H](Oc2ccc3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B02 compound treatment 144040.0 -14800.0 -0.46 138120.0 -12100.0 -0.31 -0.5468 -0.9828 3554879 ACon1_000984 COc1cc(ccc1O)C2C(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(CO)Cc4cc(OC)c(O)cc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B03 compound treatment 142640.0 -16200.0 -0.5 135320.0 -14900.0 -0.39 -0.6289 -0.9916 3559896 ACon1_000985 COc1ccc(cc1OC)c2oc3cc(OC)c(OC)c(O)c3c(=O)c2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B04 compound treatment 106120.0 -52700.0 -1.63 103640.0 -46600.0 -1.21 -2.0111 -0.9891 2060503 ACon1_000986 C1Oc2ccc(cc2O1)[C@H]3OC[C@@H]4[C@@H](OC[C@H]34)c5ccc6OCOc6c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B05 compound treatment 155440.0 -3420.0 -0.11 144400.0 -5810.0 -0.15 -0.1817 -0.9851 3557603 ACon1_000987 CC1(CCCC2(C)C3CCC4CC3(CC4(O)CO)CCC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B06 compound treatment 141000.0 -17900.0 -0.55 136240.0 -14000.0 -0.36 -0.6479 -0.979 3559134 ACon1_000988 Oc1ccc(cc1O)C2CC(=O)c3ccc(O)c(O)c3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B07 compound treatment 122520.0 -36300.0 -1.13 108240.0 -42000.0 -1.09 -1.5673 -0.9999 3558984 ACon1_000989 C/C(=C\CCC1(C)C2CC3C(C2)C31C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B08 compound treatment 126240.0 -32600.0 -1.01 134280.0 -15900.0 -0.41 -1.0073 -0.9223 3559662 ACon1_000990 COC1=CC(=O)O[C@@H](CCc2ccccc2)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B09 compound treatment 10840.0 -148000.0 -4.59 10280.0 -140000.0 -3.64 -5.8139 -0.9934 3554161 ACon1_000991 CCC(C)CC(C)/C=C(\C)/[C@H]1OC2=C([C@@H](O)[C@@H]1O)C(=C)N(OC)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B10 compound treatment 104560.0 -54300.0 -1.68 133240.0 -17000.0 -0.44 -1.5014 -0.8632 3558358 ACon1_000992 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)[C@H](C)OC(=O)/C=C/c5ccc(O)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B11 compound treatment 131040.0 -27800.0 -0.86 145320.0 -4890.0 -0.13 -0.6993 -0.8026 3558976 ACon1_000993 COc1ccc(cc1)C2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B12 compound treatment 139880.0 -19000.0 -0.59 161120.0 10900.0 0.28 -0.2154 -0.3298 2102488 ACon1_000994 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B13 mock treatment 153840.0 -5020.0 -0.16 155320.0 5110.0 0.13 -0.0161 -0.0786 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B14 mock treatment 150560.0 -8300.0 -0.26 146520.0 -3690.0 -0.1 -0.2496 -0.9094 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B15 compound treatment 10720.0 -148000.0 -4.59 10960.0 -139000.0 -3.62 -5.804 -0.9931 3559076 ACon1_000995 CC1C2C(CC3C4CC=C5C[C@@H](O)CC(O)[C@]5(C)C4CC[C@]23C)OC61CCC(C)CO6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B16 compound treatment 126240.0 -32600.0 -1.01 126920.0 -23300.0 -0.61 -1.1426 -0.9699 3558644 ACon1_000996 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c3c(cc(=O)oc3c1)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B17 compound treatment 121280.0 -37600.0 -1.16 110480.0 -39700.0 -1.03 -1.5533 -0.9982 3559113 ACon1_000997 Cc1c(O)c(C)c2oc(cc(=O)c2c1O)c3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B18 compound treatment 153680.0 -5180.0 -0.16 142240.0 -7970.0 -0.21 -0.2599 -0.9921 3559079 ACon1_000998 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3ccc(C=C)cc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B19 compound treatment 126200.0 -32700.0 -1.01 127800.0 -22400.0 -0.58 -1.1273 -0.9655 3558382 ACon1_000999 C[C@@H]1OC(O[C@H]2[C@H](O)[C@@H](COC(=O)/C=C/c3ccc(O)c(O)c3)O[C@@H](OCCc4ccc(O)c(O)c4)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B20 compound treatment 150680.0 -8180.0 -0.25 140080.0 -10100.0 -0.26 -0.3653 -0.9998 3559123 ACon1_001000 O[C@@]12CO[C@@H]([C@H]2CO[C@@H]1c3ccc4OCOc4c3)c5ccc6OCOc6c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B21 compound treatment 7120.0 -152000.0 -4.7 7160.0 -143000.0 -3.72 -5.9527 -0.9932 3559488 ACon1_001001 C/C=C(\COC(=O)C)/C(=O)O[C@@H]1CC2(C)OC(=CC2=O)\C(=C/[C@@H]3OC(=O)C(=C)C31)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B22 compound treatment 168800.0 9940.0 0.31 139680.0 -10500.0 -0.27 0.0243 0.0591 3553151 ACon1_001002 C[C@H]1CCCC2=CC[C@H](C[C@]12C)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B23 compound treatment 73680.0 -85200.0 -2.64 83680.0 -66500.0 -1.73 -3.0885 -0.9789 3552728 ACon1_001003 C[C@@H]1CCC2C(C)(C)CCC[C@@]2(C)[C@@]1(O)CCC(=CCO)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 B24 compound treatment 9400.0 -149000.0 -4.63 9400.0 -141000.0 -3.66 -5.8616 -0.9932 329 ACon1_001004 CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C01 compound treatment 97640.0 -61200.0 -1.9 108520.0 -41700.0 -1.08 -2.1072 -0.9647 3614681 ACon1_001005 CO[C@H]1C(=O)Nc2ccc(/C=C/C(=C)C)c(O)c2[C@]1(O)c3ccc(OC)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C02 compound treatment 105640.0 -53200.0 -1.65 109280.0 -40900.0 -1.06 -1.918 -0.9775 3558734 ACon1_001006 CC1(C)C2CC[C@]3(CC4CC[C@H]3[C@]2(C)CCC1=O)C[C@@]4(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C03 compound treatment 96040.0 -62800.0 -1.95 76320.0 -73900.0 -1.92 -2.7339 -1.0 3553883 ACon1_001007 CC1(C)Oc2c(CCO)c3occ(c4ccc(O)c(O)c4)c(=O)c3c(O)c2C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C04 compound treatment 140560.0 -18300.0 -0.57 154440.0 4230.0 0.11 -0.3232 -0.5595 3555922 ACon1_001008 OC1C(O)C(COC(=O)CC2(O)C=CC(=O)C=C2)OC(OC(=O)CC3(O)C=CC(=O)C=C3)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C05 compound treatment 144720.0 -14100.0 -0.44 153040.0 2830.0 0.07 -0.2578 -0.5801 3552112 ACon1_001009 C/C=C\1/[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)OC=C3[C@H]1CC(=O)OC[C@@H]4[C@@H](C)[C@@H](C[C@H]4C(C)CO)OC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C06 compound treatment 150880.0 -7980.0 -0.25 132920.0 -17300.0 -0.45 -0.4925 -0.9605 3558787 ACon1_001010 C[C@@H]1O[C@@H](OCC2OC(OC3C(O)C(O)C(CO)OC3OC4C(O)C(O)C(CO)OC4Oc5c(oc6cc(O)cc(O)c6c5=O)c7ccc(O)c(O)c7)C(O)C(O)C2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C07 compound treatment 131040.0 -27800.0 -0.86 131480.0 -18700.0 -0.49 -0.9536 -0.9634 3558850 ACon1_001011 C[C@@H]1C(=O)[C@@H](O)[C@]2(COC(=O)C)[C@H](CCC[C@@]32CO3)[C@]41CC(OC4OC(=O)C)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C08 compound treatment 116920.0 -41900.0 -1.3 131120.0 -19100.0 -0.5 -1.2696 -0.9127 3558834 ACon1_001012 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C09 compound treatment 120120.0 -38700.0 -1.2 138320.0 -11900.0 -0.31 -1.0672 -0.861 3554277 ACon1_001013 CCCCCC1CC(O)C(O)C(CC(=O)OC(CCC)CCCC(CC(=O)O1)OC2OC(CO)C(O)C(O)C2NC(=O)C)OC(=O)CC(C)(O)CC(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C10 compound treatment 107120.0 -51700.0 -1.6 152440.0 2230.0 0.06 -1.0926 -0.6811 3558858 ACon1_001014 CC1OC(OC2C(O)C(C)OC(OCC3OC(OC4C(C)OC(Oc5cc(O)c6c(=O)c(O)c(oc6c5)c7ccc(O)c(O)c7)C(O)C4O)C(O)C(O)C3OC(=O)/C=C/c8ccc(O)cc8)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C11 mock treatment 61480.0 -97400.0 -3.02 159440.0 9230.0 0.24 -1.9639 -0.6488 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C12 mock treatment 116960.0 -41900.0 -1.3 151080.0 874.0 0.02 -0.902 -0.6946 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C13 compound treatment 112560.0 -46300.0 -1.43 120200.0 -30000.0 -0.78 -1.5657 -0.9589 3558742 ACon1_001015 CC1=CCC2[C@](C)(CCC[C@]2(C)[C@H]1CCc3ccoc3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C14 compound treatment 95960.0 -62900.0 -1.95 138920.0 -11300.0 -0.29 -1.5855 -0.8044 3558795 ACon1_001016 CC(O)(CC(=O)O)CC(=O)OCC1OC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C15 mock treatment 149120.0 -9740.0 -0.3 150440.0 234.0 0.01 -0.2091 -0.6927 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C16 mock treatment 126720.0 -32100.0 -1.0 137400.0 -12800.0 -0.33 -0.9395 -0.8947 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C17 compound treatment 114960.0 -43900.0 -1.36 128560.0 -21600.0 -0.56 -1.3596 -0.9236 3558891 ACon1_001017 CCCC1CCCCCCCCCC(=O)OC2C(OC3OC(CO)C(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4OC(=O)C(C)CC)C(O)C3O)C(O)C(C)OC2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C18 compound treatment 9520.0 -149000.0 -4.63 10360.0 -140000.0 -3.63 -5.8413 -0.9928 3558933 ACon1_001018 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O[C@@H]3OC[C@H](O)[C@H](O)[C@H]3O)O[C@H]1O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)CC[C@@]8(CC[C@]76C)C(=O)O)C4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C19 compound treatment 109520.0 -49300.0 -1.53 126880.0 -23300.0 -0.61 -1.5096 -0.9179 3614691 ACon1_001019 CC1CC(=O)c2c(C1)ccc3C(=O)c4cccc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)c4C(=O)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C20 compound treatment 142560.0 -16300.0 -0.51 136920.0 -13300.0 -0.35 -0.6013 -0.9828 3553736 ACon1_001020 CC(NC(=O)c1ccccc1N)C(=O)N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C21 compound treatment 47280.0 -112000.0 -3.46 67040.0 -83200.0 -2.16 -3.9727 -0.9744 3558991 ACon1_001021 CCCCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C22 compound treatment 95000.0 -63900.0 -1.98 95320.0 -54900.0 -1.43 -2.4076 -0.9871 3559021 ACon1_001022 CC(=C)C(=O)O[C@H]1[C@@H]2[C@H](OC(=O)C2=C)/C=C(\CO)/CC/C=C(/C=O)\[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C23 compound treatment 84920.0 -73900.0 -2.29 84600.0 -65600.0 -1.7 -2.8254 -0.9894 1102980 ACon1_001023 COc1cc(cc(OC)c1OC)C2C3C(COC3=O)Cc4cc5OCOc5cc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 C24 compound treatment 125480.0 -33400.0 -1.03 120200.0 -30000.0 -0.78 -1.2827 -0.9903 3552625 ACon1_001024 C[C@@H]1C[C@@H](O)[C@]23CO[C@]3(CO)CCC[C@@H]2[C@]41C[C@H](OC4=O)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D01 compound treatment 144680.0 -14200.0 -0.44 151720.0 1510.0 0.04 -0.2829 -0.6412 3558448 ACon1_001025 O[C@@H]1[C@@H](O)[C@H](Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)O[C@@H]([C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D02 compound treatment 141640.0 -17200.0 -0.53 144800.0 -5410.0 -0.14 -0.4767 -0.8638 1035250 ACon1_001026 CC(=O)c1c(O)cc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D03 compound treatment 205560.0 46700.0 1.45 178720.0 28500.0 0.74 1.547 0.9517 3558681 ACon1_001027 CC(C)C1CCC(C)(O)C2CCC(C21)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D04 compound treatment 115080.0 -43800.0 -1.36 143840.0 -6370.0 -0.17 -1.0762 -0.7875 3559064 ACon1_001028 COc1cc2OC(C)(C)C=Cc2c3O[C@H](CC(=O)c13)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D05 compound treatment 210200.0 51300.0 1.59 188640.0 38400.0 1.0 1.8309 0.9748 3558585 ACon1_001029 COc1cc(C[C@H]2CO[C@@H]([C@H]2CO)c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D06 compound treatment 189680.0 30800.0 0.95 212000.0 61800.0 1.61 1.8105 0.9692 3555816 ACon1_001030 OC(=O)C(CCCCCCCCC=C)C1(CCC(=O)O1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D07 compound treatment 111720.0 -47100.0 -1.46 119200.0 -31000.0 -0.81 -1.6025 -0.9607 3557965 ACon1_001031 COc1cc2oc(c(OC)c(=O)c2c(O)c1OC)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D08 compound treatment 183880.0 25000.0 0.78 153560.0 3350.0 0.09 0.6097 0.7817 3559355 ACon1_001032 COc1cc(CC(CO)C(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)Cc3cc(OC)c(O)c(OC)c3)cc(OC)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D09 compound treatment 66600.0 -92300.0 -2.86 74560.0 -75600.0 -1.97 -3.4112 -0.9833 3558973 ACon1_001033 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D10 compound treatment 155560.0 -3300.0 -0.1 163200.0 13000.0 0.34 0.1664 0.4716 3554278 ACon1_001034 CCCCCC1OC2=C(C(O)C1(C)O)C(=O)N(OC)C2CSCC(O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D11 mock treatment 195080.0 36200.0 1.12 171880.0 21700.0 0.56 1.1917 0.9491 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D12 mock treatment 154240.0 -4620.0 -0.14 165920.0 15700.0 0.41 0.1874 0.4332 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D13 compound treatment 134240.0 -24600.0 -0.76 149320.0 -886.0 -0.02 -0.5557 -0.7281 3558978 ACon1_001035 C/C(=C\C(=O)O)/CCC1C(=C)CCC2C(C)(C)C(O)CCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D14 compound treatment 122280.0 -36600.0 -1.13 139560.0 -10600.0 -0.28 -0.9971 -0.8546 3558688 ACon1_001036 CC(C)(C=C)c1cc2cc3ccoc3cc2oc1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D15 mock treatment 190200.0 31300.0 0.97 181720.0 31500.0 0.82 1.2656 0.9964 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D16 mock treatment 207360.0 48500.0 1.5 176240.0 26000.0 0.68 1.5409 0.935 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D17 compound treatment 113440.0 -45400.0 -1.41 134160.0 -16000.0 -0.42 -1.29 -0.8788 3559116 ACon1_001037 OC(=O)[C@]1(O)C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H](OC(=O)/C=C/c3ccc(O)c(O)c3)[C@@H](C1)OC(=O)/C=C/c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D18 compound treatment 103840.0 -55000.0 -1.7 98760.0 -51400.0 -1.34 -2.1507 -0.9928 3558901 ACon1_001038 O[C@@H](CCc1ccccc1)CC(=O)CCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D19 compound treatment 85360.0 -73500.0 -2.28 107520.0 -42700.0 -1.11 -2.3946 -0.9453 3554848 ACon1_001039 COc1cc(C)c(Oc2cc(C)cc(O)c2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D20 compound treatment 151640.0 -7220.0 -0.22 168080.0 17900.0 0.46 0.1702 0.3301 3559313 ACon1_001040 COC(=O)C[C@H]1/C(=C/COC(=O)\C=C\c2ccccc2)/[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D21 compound treatment 151680.0 -7180.0 -0.22 183160.0 33000.0 0.86 0.4481 0.5065 3552014 ACon1_001041 C/C=C(/C)\C(=O)O[C@H]1C(=C)[C@@H]2C[C@]31CC[C@@H]4[C@@](C)(CCC[C@@]4(C)[C@]3(O)CC2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D22 compound treatment 143520.0 -15300.0 -0.48 140880.0 -9330.0 -0.24 -0.5075 -0.9511 3559586 ACon1_001042 CC(=O)OC/C/1=C\[C@H]2OC(=O)C(=C)[C@@H]2CC\C(=C\CC1)\CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D23 compound treatment 150200.0 -8660.0 -0.27 185320.0 35100.0 0.91 0.4554 0.4788 3554758 ACon1_001043 COc1c(ccc2Oc3c(O)cc(C)cc3COC(=O)c12)C(O)CC(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 D24 compound treatment 145120.0 -13700.0 -0.43 152480.0 2270.0 0.06 -0.2593 -0.6032 3557336 ACon1_001044 CC(O)CC1=CC(OC1=O)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E01 mock treatment 102720.0 -56100.0 -1.74 118480.0 -31700.0 -0.82 -1.8129 -0.9418 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E02 mock treatment 157160.0 -1700.0 -0.05 147840.0 -2370.0 -0.06 -0.0808 -0.9971 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E03 compound treatment 139200.0 -19700.0 -0.61 156960.0 6750.0 0.18 -0.3067 -0.4837 3553538 ACon1_001045 CC(C)C(NC(=O)C(Cc1ccccc1)NC(=O)C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E04 compound treatment 169640.0 10800.0 0.33 137440.0 -12800.0 -0.33 0.0016 0.0034 3555006 ACon1_001046 COc1cc(OC)c2C(=O)OC(C)Cc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E05 compound treatment 136760.0 -22100.0 -0.68 124400.0 -25800.0 -0.67 -0.9584 -0.9999 3558819 ACon1_001047 O[C@H]1C[C@@H]2[C@@H]([C@H]3OC(=O)C(=C)[C@@H]3[C@H](O)CC2=C)C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E06 compound treatment 143320.0 -15500.0 -0.48 140360.0 -9850.0 -0.26 -0.5214 -0.9562 3614704 ACon1_001048 Cc1c(O)cc2C(=O)C(O)(CCCO)OCc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E07 compound treatment 124240.0 -34600.0 -1.07 128160.0 -22000.0 -0.57 -1.1636 -0.9568 3558866 ACon1_001049 C[C@@H]1O[C@@H](OC[C@H]2O[C@H]([C@H](O)[C@@H](O)[C@@H]2O)c3c(O)cc4oc(cc(=O)c4c3O)c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E08 compound treatment 114440.0 -44400.0 -1.38 144240.0 -5970.0 -0.16 -1.0829 -0.7818 3558836 ACon1_001050 C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E09 mock treatment 137520.0 -21300.0 -0.66 150400.0 194.0 0.01 -0.464 -0.7017 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E10 mock treatment 155280.0 -3580.0 -0.11 145600.0 -4610.0 -0.12 -0.1631 -0.9993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E11 compound treatment 136640.0 -22200.0 -0.69 141760.0 -8450.0 -0.22 -0.6421 -0.8884 3558576 ACon1_001051 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)C(C)(C)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E12 compound treatment 143600.0 -15300.0 -0.47 145280.0 -4930.0 -0.13 -0.4249 -0.8673 3558478 ACon1_001052 CC(C)(O)c1cc(O)c2c(CCC3C(C)(CCCC32C)C(=O)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E13 compound treatment 160200.0 1340.0 0.04 154520.0 4310.0 0.11 0.1086 0.9084 3558756 ACon1_001053 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCC(C)[C@@H]3C[C@H]4OC(=O)C5=CO[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)/C(=C/C)/[C@@H]5CC(=O)OC[C@@H]3[C@H]4C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E14 compound treatment 107440.0 -51400.0 -1.59 126480.0 -23700.0 -0.62 -1.5625 -0.9146 1859 ACon1_001054 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E15 compound treatment 151000.0 -7860.0 -0.24 157120.0 6910.0 0.18 -0.0452 -0.1494 3558832 ACon1_001055 C/C/1=C\CC\C(=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@@H](O)C1)\CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E16 compound treatment 135200.0 -23700.0 -0.73 147160.0 -3050.0 -0.08 -0.5744 -0.7789 3555940 ACon1_001056 OC1CCC(=O)C(O)C1(O)C(=O)OCc2cc(O)ccc2OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E17 mock treatment 139160.0 -19700.0 -0.61 153320.0 3110.0 0.08 -0.3745 -0.6081 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E18 mock treatment 145280.0 -13600.0 -0.42 146960.0 -3250.0 -0.08 -0.3572 -0.8323 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E19 compound treatment 110720.0 -48100.0 -1.49 102760.0 -47400.0 -1.23 -1.9265 -0.9955 3557853 ACon1_001057 CC1CCC2(CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C5CCC43C)C(=O)O)C2C1(C)O)C(=O)OC6OC(CO)C(O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E20 compound treatment 138600.0 -20300.0 -0.63 156120.0 5910.0 0.15 -0.3353 -0.5187 3558986 ACon1_001058 COc1cc(CCC(O)CC(O)CCc2ccc(O)c(OC)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E21 compound treatment 9440.0 -149000.0 -4.63 9360.0 -141000.0 -3.66 -5.8615 -0.9932 3559000 ACon1_001059 CCCCCCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E22 compound treatment 108320.0 -50500.0 -1.57 107000.0 -43200.0 -1.12 -1.9012 -0.9867 3559026 ACon1_001060 CC1(C)[C@@H](O)CC[C@@]2(C)[C@@H]3CC[C@@](C)(C=C3CC[C@H]12)C(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E23 compound treatment 101040.0 -57800.0 -1.79 92920.0 -57300.0 -1.49 -2.3193 -0.9958 3558682 ACon1_001061 CC(C)c1ccc2c(c1)C(O)CC3C(C)(CO)CCCC32C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 E24 compound treatment 101560.0 -57300.0 -1.78 111560.0 -38600.0 -1.0 -1.9655 -0.9636 3552689 ACon1_001062 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@@H](O)C(C)(C)C5CC[C@]43C)C2[C@]1(C)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F01 mock treatment 128240.0 -30600.0 -0.95 145480.0 -4730.0 -0.12 -0.7577 -0.792 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F02 mock treatment 152000.0 -6860.0 -0.21 153400.0 3190.0 0.08 -0.0917 -0.4016 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F03 compound treatment 95920.0 -62900.0 -1.95 95960.0 -54200.0 -1.41 -2.3757 -0.9873 3558778 ACon1_001063 Oc1ccc(/C=C/c2cc(O)cc(O)c2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F04 compound treatment 158920.0 57.4 0.0 177600.0 27400.0 0.71 0.5046 0.7089 3559033 ACon1_001064 COc1cc(ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F05 compound treatment 149440.0 -9420.0 -0.29 137360.0 -12800.0 -0.33 -0.4425 -0.9978 425 ACon1_001065 Oc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F06 compound treatment 158160.0 -703.0 -0.02 151320.0 1110.0 0.03 0.0051 0.1403 3559139 ACon1_001066 C[C@]1(CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@@]3(CCC12)C(=O)C4=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F07 compound treatment 89520.0 -69300.0 -2.15 88120.0 -62100.0 -1.61 -2.6599 -0.99 3558995 ACon1_001067 CCCCCCCC(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F08 compound treatment 169480.0 10600.0 0.33 152480.0 2270.0 0.06 0.2744 0.821 3557648 ACon1_001068 OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)/C=C/c2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F09 mock treatment 158400.0 -463.0 -0.01 148000.0 -2210.0 -0.06 -0.0507 -0.8575 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F10 mock treatment 155560.0 -3300.0 -0.1 154680.0 4470.0 0.12 0.0098 0.0636 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F11 compound treatment 156800.0 -2060.0 -0.06 147120.0 -3090.0 -0.08 -0.1019 -0.9937 3558481 ACon1_001069 COc1cc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F12 compound treatment 162280.0 3420.0 0.11 171080.0 20900.0 0.54 0.4584 0.8295 3557470 ACon1_001070 CCc1cc(O)c(C)c(O)c1C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F13 compound treatment 136280.0 -22600.0 -0.7 143880.0 -6330.0 -0.16 -0.611 -0.8501 3559015 ACon1_001071 Oc1ccc(cc1)[C@H]2CC(=O)c3c(O)cc(O)c([C@H]4[C@@H](Oc5cc(O)cc(O)c5C4=O)c6ccc(O)cc6)c3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F14 compound treatment 163560.0 4700.0 0.15 173000.0 22800.0 0.59 0.5217 0.8554 3555967 ACon1_001072 OCC1OC(OC(CCc2ccccc2)CC(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F15 compound treatment 157720.0 -1140.0 -0.04 149160.0 -1050.0 -0.03 -0.0442 -0.9915 3557355 ACon1_001073 CCCC[C@@H](O)c1cc(OC)cc(=O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F16 compound treatment 118800.0 -40100.0 -1.24 135400.0 -14800.0 -0.38 -1.1498 -0.8847 3558989 ACon1_001074 CCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F17 mock treatment 166360.0 7500.0 0.23 161760.0 11600.0 0.3 0.3765 0.992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F18 mock treatment 158560.0 -303.0 -0.01 153960.0 3750.0 0.1 0.0623 0.6362 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F19 compound treatment 194000.0 35100.0 1.09 184160.0 34000.0 0.88 1.3937 0.9946 3559597 ACon1_001075 COc1cc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O)c(OC)c3)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F20 compound treatment 24440.0 -134000.0 -4.17 39320.0 -111000.0 -2.88 -4.9824 -0.9838 3552025 ACon1_001076 C/C=C(\C)/C(=O)O[C@H]1C=CC(=O)O[C@H]1\C=C\[C@H](O)[C@H](C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F21 compound treatment 83160.0 -75700.0 -2.35 67560.0 -82600.0 -2.15 -3.177 -0.999 3553341 ACon1_001077 CC(=O)O[C@@H]1CC2[C@@]3(C)CCC(OC(=O)CC(=O)O)C(C)(C)C3CC[C@@]2(C)[C@]4(C)CCC(O)(C14)[C@]5(C)CCC(O5)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F22 compound treatment 83600.0 -75300.0 -2.33 85880.0 -64300.0 -1.67 -2.8308 -0.9867 3555308 ACon1_001078 COc1cccc2C(=O)c3c(ccc4CC(C)(O)CC(=O)c43)C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F23 compound treatment 64520.0 -94300.0 -2.92 57440.0 -92800.0 -2.41 -3.7713 -0.9954 3559897 ACon1_001079 CC(=CCc1c(O)cc(O)c2c(=O)cc(oc12)c3ccc(O)cc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 F24 compound treatment 120120.0 -38700.0 -1.2 118480.0 -31700.0 -0.82 -1.4317 -0.9832 3558760 ACon1_001080 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@@H](O)C[C@@]31O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G01 compound treatment 107920.0 -50900.0 -1.58 103760.0 -46400.0 -1.21 -1.9694 -0.9912 3558179 ACon1_001081 COc1cc(CCCO)cc2C(COC3OC(CO)C(O)C(O)C3O)C(Oc21)c4ccc(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G02 compound treatment 13800.0 -145000.0 -4.49 12520.0 -138000.0 -3.58 -5.7079 -0.9936 3554828 ACon1_001082 COc1cc(c(O)c(O)c1c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G03 mock treatment 159720.0 857.0 0.03 153720.0 3510.0 0.09 0.0834 0.8765 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G04 mock treatment 161920.0 3060.0 0.09 135080.0 -15100.0 -0.39 -0.2109 -0.5217 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G05 compound treatment 165640.0 6780.0 0.21 135760.0 -14400.0 -0.38 -0.1169 -0.2718 3555886 ACon1_001083 OC[C@H]1O[C@@H](O[C@H]2C[C@@H]3[C@@H]([C@H]4OC(=O)C(=C)[C@@H]4[C@H](O)CC3=C)C2=C)[C@H](O)[C@@H](O)[C@@H]1OC(=O)/C=C/c5ccc(O)c(O)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G06 compound treatment 154040.0 -4820.0 -0.15 137360.0 -12800.0 -0.33 -0.3417 -0.9343 3614713 ACon1_001084 CC1CC(O)c2c(C1)ccc3C(O)c4c(O)cccc4C(=O)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G07 compound treatment 163080.0 4220.0 0.13 139160.0 -11000.0 -0.29 -0.1105 -0.3505 3558875 ACon1_001085 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3CC=C(CO)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G08 compound treatment 150000.0 -8860.0 -0.27 152720.0 2510.0 0.07 -0.148 -0.5242 3558860 ACon1_001086 C/C(=C\CCC(C)(O)C=C)/C(=O)OCC1CCC2C1C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G09 compound treatment 129280.0 -29600.0 -0.92 136040.0 -14200.0 -0.37 -0.9084 -0.9197 3558972 ACon1_001087 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@H]1C)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G10 compound treatment 98560.0 -60300.0 -1.87 122800.0 -27400.0 -0.71 -1.8247 -0.9126 3557781 ACon1_001088 O[C@H]1[C@@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G11 compound treatment 12880.0 -146000.0 -4.52 13920.0 -136000.0 -3.54 -5.7023 -0.9927 1105254 ACon1_001089 CC12CCC3C4(C)C=CC(=O)C(C)(C)C4CC(O)C3(C)C2=CCC1c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G12 compound treatment 146240.0 -12600.0 -0.39 141520.0 -8690.0 -0.23 -0.4361 -0.9659 3558250 ACon1_001090 CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H]2Oc3cc4oc(=O)ccc4cc3[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G13 compound treatment 158400.0 -463.0 -0.01 127200.0 -23000.0 -0.6 -0.4328 -0.7239 3553160 ACon1_001091 C[C@H]1OC(=O)[C@@H](C)[C@@H]1C[C@@H](O)[C@](C)(O)[C@H]2CC[C@@]3(O)C4=CC(=O)[C@@H]5C[C@@H](O)[C@@H](O)C[C@]5(C)C4CC[C@]23C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G14 compound treatment 164680.0 5820.0 0.18 154880.0 4670.0 0.12 0.2133 0.9815 3558272 ACon1_001092 C[C@H]1[C@H](C[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O)OC(=O)/C=C/c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G15 compound treatment 39640.0 -119000.0 -3.69 34160.0 -116000.0 -3.02 -4.7441 -0.9949 3558437 ACon1_001093 CO[C@@H]1CC(OC2CCC3(C)C(CCC4(CCC(C5=CC(=O)OC5)C6(C)CCC34)C6=O)C2)O[C@H](C)[C@@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G16 compound treatment 37400.0 -121000.0 -3.76 60520.0 -89700.0 -2.33 -4.3089 -0.9734 3559145 ACon1_001094 CC(C)(O)CC(O)CC(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G17 compound treatment 153880.0 -4980.0 -0.15 147480.0 -2730.0 -0.07 -0.1592 -0.9375 3557962 ACon1_001095 OC[C@H]1O[C@@H](O[C@@H]2OC=CC3C(O)C=C(COC(=O)c4ccccc4)C32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G18 compound treatment 161400.0 2540.0 0.08 155680.0 5470.0 0.14 0.1562 0.9609 3558116 ACon1_001096 COc1c(O)c2c(=O)cc(oc2cc1O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(=O)O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G19 mock treatment 166320.0 7460.0 0.23 146080.0 -4130.0 -0.11 0.0876 0.3439 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G20 mock treatment 150800.0 -8060.0 -0.25 144320.0 -5890.0 -0.15 -0.2848 -0.9723 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G21 compound treatment 178640.0 19800.0 0.61 158040.0 7830.0 0.2 0.5772 0.894 3554700 ACon1_001097 COC(=O)c1cc(CO)cc(O)c1C(=O)c2c(O)cccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G22 compound treatment 134160.0 -24700.0 -0.77 130920.0 -19300.0 -0.5 -0.8955 -0.9789 3558581 ACon1_001098 C[C@@]1(CCC[C@]2(C)C3CCC4CC3(CCC12)C=C4CO)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G23 compound treatment 123520.0 -35300.0 -1.1 110120.0 -40100.0 -1.04 -1.5108 -0.9997 3555287 ACon1_001099 COc1ccc2c(C=O)c(oc2c1)c3ccc(OC)c(O)c3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 G24 compound treatment 6760.0 -152000.0 -4.71 6560.0 -144000.0 -3.73 -5.9716 -0.9933 1787154 ACon1_001100 CC(=CCc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccccc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H01 compound treatment 123000.0 -35900.0 -1.11 112960.0 -37200.0 -0.97 -1.47 -0.9976 3558364 ACon1_001101 CCCCCOC(=O)c1ccccc1C(=O)OCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H02 compound treatment 87040.0 -71800.0 -2.23 77920.0 -72300.0 -1.88 -2.9017 -0.9964 3558698 ACon1_001102 CC(=O)OC/C=C(\CO)/CC/C=C(\C)/CC/C=C(\CC/C=C(\C)/COC(=O)C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H03 mock treatment 148920.0 -9940.0 -0.31 151560.0 1350.0 0.04 -0.193 -0.6223 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H04 mock treatment 163040.0 4180.0 0.13 133560.0 -16600.0 -0.43 -0.2143 -0.4747 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H05 compound treatment 161280.0 2420.0 0.07 154320.0 4110.0 0.11 0.1286 0.9849 3558811 ACon1_001103 COc1cc(/C=C/C=O)cc(OC)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H06 compound treatment 147280.0 -11600.0 -0.36 149680.0 -526.0 -0.01 -0.2634 -0.7335 3559864 ACon1_001104 OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](C[C@@H]4N(Cc5c4nc6ccccc6c5O)C3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H07 compound treatment 152480.0 -6380.0 -0.2 140280.0 -9930.0 -0.26 -0.3222 -0.9914 3557308 ACon1_001105 CCCCCCCCC(C(O)CC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H08 compound treatment 175440.0 16600.0 0.51 153360.0 3150.0 0.08 0.4212 0.8097 1001923 ACon1_001106 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H09 compound treatment 153200.0 -5660.0 -0.18 163960.0 13800.0 0.36 0.1286 0.3231 3557902 ACon1_001107 COc1cc(cc(OC)c1O)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4cc(OC)c(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H10 compound treatment 21040.0 -138000.0 -4.27 60800.0 -89400.0 -2.32 -4.6622 -0.959 3553984 ACon1_001108 Cc1cc(O)c(Cc2c(O)cc(C)c(C=O)c2O)c(O)c1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H11 compound treatment 81080.0 -77800.0 -2.41 84080.0 -66100.0 -1.72 -2.9191 -0.9862 3559002 ACon1_001109 Oc1ccc(CCCc2ccc3OCOc3c2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H12 compound treatment 151320.0 -7540.0 -0.23 169880.0 19700.0 0.51 0.1962 0.3491 3554509 ACon1_001110 CO[C@H]/1\C=C\[C@@](C)(O)/C=C/C(=O)O[C@H](C)[C@@H](C)CC\C=C1/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H13 compound treatment 99480.0 -59400.0 -1.84 99160.0 -51000.0 -1.33 -2.2389 -0.9871 3559031 ACon1_001111 CC(C)(O)CCC(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)C3CC=C4C(C[C@H](O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H14 compound treatment 14440.0 -144000.0 -4.47 13800.0 -136000.0 -3.54 -5.6703 -0.9933 3554525 ACon1_001112 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)C(C)(O)CCl)C1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H15 compound treatment 128680.0 -30200.0 -0.94 133800.0 -16400.0 -0.43 -0.9627 -0.9367 3553997 ACon1_001113 Cc1cc(O)cc2oc3cc(O)cc(O)c3c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H16 compound treatment 177480.0 18600.0 0.58 159120.0 8910.0 0.23 0.5717 0.9197 1106761 ACon1_001114 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C(C=C)C1CC3CC(=O)CC(CC(=O)CCc4ccc(O)cc4)O3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H17 compound treatment 169720.0 10900.0 0.34 159840.0 9630.0 0.25 0.4149 0.9894 3559112 ACon1_001115 C[C@@H]([C@H]1CC[C@](C)(O1)C=C)C(=O)/C=C/C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H18 compound treatment 165960.0 7100.0 0.22 169880.0 19700.0 0.51 0.517 0.929 3558839 ACon1_001116 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H19 mock treatment 178800.0 19900.0 0.62 161600.0 11400.0 0.3 0.6462 0.9433 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H20 mock treatment 151800.0 -7060.0 -0.22 142800.0 -7410.0 -0.19 -0.2908 -0.9979 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H21 compound treatment 159520.0 657.0 0.02 159520.0 9310.0 0.24 0.1855 0.7639 1111461 ACon1_001117 CC(=CCOc1c2occc2cc3ccc(=O)oc13)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H22 compound treatment 10640.0 -148000.0 -4.59 11640.0 -139000.0 -3.6 -5.7933 -0.9927 3558469 ACon1_001118 OC(=O)c1c(O)cccc1CCCCCCC/C=C\C/C=C\CC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H23 compound treatment 118600.0 -40300.0 -1.25 110320.0 -39900.0 -1.04 -1.6149 -0.9958 3559898 ACon1_001119 C[C@@H]1C(O)O[C@@H]2[C@H]1[C@@H](O)C[C@](C)(C=C)[C@H]2C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 H24 compound treatment 109360.0 -49500.0 -1.53 112200.0 -38000.0 -0.99 -1.7828 -0.9773 3559171 ACon1_001120 OC[C@H]1O[C@@H](Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4C(=O)C[C@@H](Oc4c2)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I01 compound treatment 8040.0 -151000.0 -4.67 6800.0 -143000.0 -3.73 -5.9392 -0.9937 3554132 ACon1_001121 CCC(C)C(=O)c1c(O)cc2OC(C)(C)C(CC=C(C)C)Cc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I02 compound treatment 10320.0 -149000.0 -4.6 8760.0 -141000.0 -3.68 -5.8532 -0.9938 3553195 ACon1_001122 CC(=CCc1c(oc2c(CC=C(C)C)c(O)cc(O)c2c1=O)c3ccc(O)cc3O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I03 compound treatment 24120.0 -135000.0 -4.17 24600.0 -126000.0 -3.26 -5.2598 -0.9926 3559282 ACon1_001123 OC[C@H]1O[C@@H](Oc2ccc(CC=C)cc2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I04 compound treatment 171320.0 12500.0 0.39 169840.0 19600.0 0.51 0.6337 0.9905 3558801 ACon1_001124 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H]3C(=C[C@@H](O)[C@@]3(C)O)[C@@](C)(O)C[C@@H]2OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I05 mock treatment 188880.0 30000.0 0.93 147720.0 -2490.0 -0.06 0.612 0.6564 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I06 mock treatment 164040.0 5180.0 0.16 150960.0 754.0 0.02 0.1273 0.7876 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I07 compound treatment 210240.0 51400.0 1.59 163320.0 13100.0 0.34 1.3666 0.8394 3474459 ACon1_001125 OCC1OC(Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)C(OC5OCC(O)(CO)C5O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I08 compound treatment 150400.0 -8460.0 -0.26 148160.0 -2050.0 -0.05 -0.223 -0.8335 3554178 ACon1_001126 CCC(CCCCC(=O)CCCCC1CCC(=O)O1)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](OC(=O)/C=C/c4ccc(O)cc4)[C@H](OC(=O)C)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I09 compound treatment 14360.0 -145000.0 -4.48 14280.0 -136000.0 -3.53 -5.6633 -0.9931 3558998 ACon1_001127 CCCCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I10 compound treatment 157520.0 -1340.0 -0.04 155200.0 4990.0 0.13 0.0623 0.4575 3557509 ACon1_001128 OCC1OC(C(O)C(O)C1O)c2c(O)c(C3OCC(O)C(O)C3O)c(O)c4c(=O)cc(oc24)c5ccc(O)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I11 compound treatment 167880.0 9020.0 0.28 160960.0 10800.0 0.28 0.3952 1.0 3558722 ACon1_001129 CC1OC(OCC2OC(OCCc3ccc(O)c(O)c3)C(OC(=O)C)C(OC4OC(C)C(O)C(O)C4O)C2OC(=O)/C=C/c5ccc(O)c(O)c5)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I12 compound treatment 163040.0 4180.0 0.13 181600.0 31400.0 0.82 0.6683 0.8092 3558629 ACon1_001130 OC[C@H]1O[C@@H](Oc2cc3occc3cc2CCC(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I13 compound treatment 170840.0 12000.0 0.37 156520.0 6310.0 0.16 0.3784 0.9326 3558785 ACon1_001131 CC1(C)C2CCC1(C)C(C2)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I14 compound treatment 128000.0 -30900.0 -0.96 122160.0 -28000.0 -0.73 -1.1915 -0.991 3558926 ACon1_001132 Oc1ccc(/C=C/c2ccc(O)cc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I15 compound treatment 189760.0 30900.0 0.96 160240.0 10000.0 0.26 0.8613 0.8681 3558862 ACon1_001133 CC1CCC2C1C(OC3OC(CO)C(O)C(O)C3O)OC=C2C(=O)OC4C5OC5(C)C6C(OC7OC(CO)C(OC(=O)/C(=C/CCC(C)(O)C=C)/C)C(O)C7O)OC=CC46O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I16 compound treatment 164560.0 5700.0 0.18 156800.0 6590.0 0.17 0.246 0.9999 3558948 ACon1_001134 COc1cc(/C=C\C(=O)O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I17 compound treatment 172560.0 13700.0 0.42 163600.0 13400.0 0.35 0.5462 0.9951 3557339 ACon1_001135 C[C@H]1OC(=O)c2c(O)ccc(O)c2[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I18 compound treatment 147680.0 -11200.0 -0.35 147920.0 -2290.0 -0.06 -0.287 -0.8164 3557346 ACon1_001136 CC(C)CCCC/C=C\CCCCCCCC(=O)OCC(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I19 compound treatment 73120.0 -85700.0 -2.66 80240.0 -70000.0 -1.82 -3.164 -0.9829 3557913 ACon1_001137 CC1OC(OC2C(O)C(O)COC2OC3C(O)C(O)C(OC3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7C8CC(C)(C)CC(O)[C@]8(C)CC[C@]76C)C4(C)C)C(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I20 compound treatment 142080.0 -16800.0 -0.52 150600.0 394.0 0.01 -0.3604 -0.693 3558986 ACon1_001138 COc1cc(CCC(O)CC(O)CCc2ccc(O)c(OC)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I21 mock treatment 174400.0 15500.0 0.48 168840.0 18600.0 0.48 0.6828 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I22 mock treatment 159520.0 657.0 0.02 151080.0 874.0 0.02 0.0305 0.9985 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I23 compound treatment 9920.0 -149000.0 -4.61 10240.0 -140000.0 -3.64 -5.8348 -0.993 3554969 ACon1_001139 COc1cc(O)c(CC=C(C)C)cc1C(=O)/C=C/c2ccc(O)c(CC=C(C)C)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 I24 compound treatment 116760.0 -42100.0 -1.3 136080.0 -14100.0 -0.37 -1.182 -0.8722 3554553 ACon1_001140 COC(=O)[C@]1(C)CC[C@H](O)[C@@]2(C)C1C[C@@H](OC(=O)C)C3=C2[C@H](O)C[C@](C)(C=C)[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J01 compound treatment 154600.0 -4260.0 -0.13 156920.0 6710.0 0.17 0.03 0.137 3557527 ACon1_001141 OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J02 compound treatment 147400.0 -11500.0 -0.36 151760.0 1550.0 0.04 -0.2226 -0.6227 3558547 ACon1_001142 COc1ccc(cc1OC)[C@@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J03 compound treatment 124360.0 -34500.0 -1.07 132600.0 -17600.0 -0.46 -1.0794 -0.9283 3554707 ACon1_001143 COC(=O)c1cc(O)cc(OC)c1Oc2c(Cl)c(C)c(Cl)c(O)c2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J04 compound treatment 161040.0 2180.0 0.07 152240.0 2030.0 0.05 0.0851 0.9927 3559048 ACon1_001144 CC(C)(O)C(O)Cc1cc2ccc(=O)oc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J05 mock treatment 169680.0 10800.0 0.34 151120.0 914.0 0.02 0.2538 0.7553 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J06 mock treatment 191080.0 32200.0 1.0 145920.0 -4290.0 -0.11 0.6271 0.6244 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J07 compound treatment 16040.0 -143000.0 -4.43 13720.0 -136000.0 -3.55 -5.6367 -0.994 3559004 ACon1_001145 Oc1cc(O)c(C(=O)CCCCCCCCc2ccccc2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J08 compound treatment 180800.0 21900.0 0.68 164720.0 14500.0 0.38 0.7473 0.9614 3558537 ACon1_001146 C/C(=C\CC1C(=C)CCC2C(C)(CCCC12C)C(=O)O)/C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J09 compound treatment 154720.0 -4140.0 -0.13 172920.0 22700.0 0.59 0.3266 0.5407 3558931 ACon1_001147 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3O[C@@H](CC(=O)c3c2O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J10 compound treatment 165320.0 6460.0 0.2 151440.0 1230.0 0.03 0.1642 0.8101 3557887 ACon1_001148 COc1cc(ccc1O)C2OCC3C(OCC23)c4ccc(OC5OC(CO)C(O)C(O)C5O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J11 compound treatment 140800.0 -18100.0 -0.56 135160.0 -15000.0 -0.39 -0.6722 -0.9846 3557666 ACon1_001149 CC(=O)OCC(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J12 compound treatment 73800.0 -85100.0 -2.64 75480.0 -74700.0 -1.94 -3.2366 -0.9887 3554146 ACon1_001150 CCC(C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J13 compound treatment 167160.0 8300.0 0.26 147280.0 -2930.0 -0.08 0.128 0.4776 3559043 ACon1_001151 CC(C)(O)C1CCC(C)(O1)C2[C@H](O)C[C@@]3(C)C4CC=C5C(C[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)C5(C)C)[C@]4(C)C(=O)C[C@]23C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J14 compound treatment 175560.0 16700.0 0.52 161280.0 11100.0 0.29 0.5693 0.9617 3557343 ACon1_001152 CCC/C=C\CC(N)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J15 compound treatment 175840.0 17000.0 0.53 174000.0 23800.0 0.62 0.8091 0.9968 3559081 ACon1_001153 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3ccc(C=C)cc3)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J16 compound treatment 50760.0 -108000.0 -3.35 89840.0 -60400.0 -1.57 -3.4775 -0.9402 3552097 ACon1_001154 C/C=C/C=C/C=C/C(=O)O[C@@H]1C=C2CO[C@@H](O)[C@]2(O)[C@@]3(C)CCCC(C)(C)[C@H]13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J17 compound treatment 194800.0 35900.0 1.11 186280.0 36100.0 0.94 1.4501 0.9963 3559133 ACon1_001155 OC1C(O)c2ccc(O)c(O)c2OC1c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J18 compound treatment 193080.0 34200.0 1.06 182200.0 32000.0 0.83 1.3375 0.9928 3558873 ACon1_001156 O[C@H]1[C@@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J19 compound treatment 160800.0 1940.0 0.06 160160.0 9950.0 0.26 0.2253 0.8487 3554748 ACon1_001157 COC1=CC(=O)O[C@@H](/C=C/c2ccccc2)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J20 compound treatment 172200.0 13300.0 0.41 166320.0 16100.0 0.42 0.5883 1.0 3558844 ACon1_001158 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J21 mock treatment 186000.0 27100.0 0.84 158480.0 8270.0 0.21 0.7466 0.8602 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J22 mock treatment 147840.0 -11000.0 -0.34 157280.0 7070.0 0.18 -0.1115 -0.2875 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J23 compound treatment 119360.0 -39500.0 -1.22 162320.0 12100.0 0.31 -0.6429 -0.5087 3555129 ACon1_001159 COc1ccc(cc1)C2(O)C(O)C(=O)Nc3ccccc32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 J24 compound treatment 92200.0 -66700.0 -2.07 103240.0 -47000.0 -1.22 -2.3234 -0.9685 3552652 ACon1_001160 C[C@@H]1C[C@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@H](COC(=O)C)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H]2O)[C@]4(C)[C@H](CCC=C4C)[C@@]1(C)CC[C@](C)(O[C@@H]5O[C@H](C)[C@H](O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)[C@H](O)[C@H]5O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K01 compound treatment 140640.0 -18200.0 -0.56 148600.0 -1610.0 -0.04 -0.4287 -0.7573 3554770 ACon1_001161 COc1c(O)cc2C(Oc3cc4C(O)C(C)OC(=O)c4c(O)c3OC)C(C)OC(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K02 compound treatment 99040.0 -59800.0 -1.85 107040.0 -43200.0 -1.12 -2.1037 -0.971 3558741 ACon1_001162 C[C@@]1(CCC[C@]2(C)[C@@H](CCc3ccoc3)C(=C)CCC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K03 compound treatment 161520.0 2660.0 0.08 156640.0 6430.0 0.17 0.1764 0.9468 3558575 ACon1_001163 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)[C@@](C)(CO)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K04 compound treatment 168520.0 9660.0 0.3 157880.0 7670.0 0.2 0.3526 0.9805 3553892 ACon1_001164 CC1[C@@H]2CC[C@@]3(C)[C@H](O)C[C@H](O)C(=C)C3[C@H]2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K05 compound treatment 149200.0 -9660.0 -0.3 145200.0 -5010.0 -0.13 -0.3037 -0.9303 3558807 ACon1_001165 C[C@H]1[C@@H]2CC/C(=C/C[C@H](O)/C(=C/[C@H]2OC1=O)/C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K06 compound treatment 155080.0 -3780.0 -0.12 167720.0 17500.0 0.46 0.2389 0.5084 3552732 ACon1_001166 C[C@@H]1N2[C@H]3N(C1=O)c4ccccc4[C@@]3(O)C[C@@H]5C(=O)N[C@]2(C)c6nc7ccccc7c(=O)n56 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K07 mock treatment 157600.0 -1260.0 -0.04 130400.0 -19800.0 -0.51 -0.3915 -0.7587 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K08 mock treatment 152920.0 -5940.0 -0.18 151120.0 914.0 0.02 -0.1134 -0.6108 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K09 compound treatment 173680.0 14800.0 0.46 162880.0 12700.0 0.33 0.5575 0.9867 3558702 ACon1_001167 CC(=CCC/C(=C/CC/C(=C/CC\C(=C\COC(=O)C)\COC(=O)C)/C)/C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K10 compound treatment 171560.0 12700.0 0.39 167360.0 17200.0 0.45 0.5934 0.9981 3558881 ACon1_001168 COc1cc(ccc1O)[C@H]2Oc3c(cc(CCCO)cc3O)[C@@H]2CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K11 compound treatment 158720.0 -143.0 0.0 151960.0 1750.0 0.05 0.0291 0.6356 3558728 ACon1_001169 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)c([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)c(C(=O)CCc4ccc(O)cc4)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K12 compound treatment 160360.0 1500.0 0.05 168640.0 18400.0 0.48 0.3715 0.772 3558883 ACon1_001170 COc1c(CCC(=O)O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc3occc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K13 compound treatment 170120.0 11300.0 0.35 152880.0 2670.0 0.07 0.2958 0.8316 3558821 ACon1_001171 OCC1OC(OC2CC3C(C4OC(=O)C(=C)C4C(O)CC3=C)C2=C)C(O)C(OC(=O)/C=C/c5ccc(O)c(O)c5)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K14 compound treatment 175640.0 16800.0 0.52 146440.0 -3770.0 -0.1 0.2984 0.5641 3558928 ACon1_001172 CC(C)C1C(OC(=O)/C=C/c2ccccc2)C3OC1CC(C)(O)C(O)CCC3(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K15 mock treatment 158760.0 -103.0 0.0 158200.0 7990.0 0.21 0.1446 0.6962 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K16 mock treatment 165360.0 6500.0 0.2 168200.0 18000.0 0.47 0.473 0.9291 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K17 compound treatment 47640.0 -111000.0 -3.45 79880.0 -70300.0 -1.83 -3.7289 -0.956 3558508 ACon1_001173 CC(C)C(=O)O[C@@H]1[C@@H](OC(=O)C)[C@@H](OC(=O)C)C(C)(C)/C=C/C(C)C(=O)C2(O)C[C@@](C)(OC(=O)C)[C@H](OC(=O)C)C2[C@H]3OC(=O)CC[C@]31OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K18 compound treatment 186000.0 27100.0 0.84 162000.0 11800.0 0.31 0.8113 0.9065 3558941 ACon1_001174 CC(C)CC(=O)c1c(O)cc(O)cc1OC2OC(COC(=O)c3cc(O)c(O)c(O)c3)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K19 compound treatment 14480.0 -144000.0 -4.47 16400.0 -134000.0 -3.48 -5.6217 -0.9922 3558693 ACon1_001175 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)C(C)(O)C(C)Cl)C1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K20 compound treatment 125960.0 -32900.0 -1.02 125640.0 -24600.0 -0.64 -1.1722 -0.9746 3558988 ACon1_001176 CCCCCC(O)CC(O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K21 compound treatment 14440.0 -144000.0 -4.47 16320.0 -134000.0 -3.48 -5.624 -0.9922 3559019 ACon1_001177 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](C)O[C@@H](O[C@@H]4[C@@H](O)[C@@H](O)CO[C@H]4O[C@H]5CC[C@@]6(C)C(CC[C@]7(C)C6CC=C8[C@@H]9CC(C)(C)CC[C@@]9(CC[C@]87C)C(=O)O)[C@]5(C)CO)[C@@H]3O)O[C@H](CO)[C@H]2O[C@@H]%10O[C@H](CO)[C@@H](O[C@@H]%11OC[C@@H](O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K22 compound treatment 113800.0 -45100.0 -1.4 132080.0 -18100.0 -0.47 -1.3203 -0.896 3559027 ACon1_001178 CC(=O)OC[C@]1(O)C[C@@]2(C[C@H]1CC[C@H]23)CC[C@@H]4[C@@](C)(CCC[C@@]34C)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K23 mock treatment 151920.0 -6940.0 -0.22 151640.0 1430.0 0.04 -0.1258 -0.576 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 K24 mock treatment 152080.0 -6780.0 -0.21 156560.0 6350.0 0.17 -0.0319 -0.1192 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L01 compound treatment 153560.0 -5300.0 -0.16 155960.0 5750.0 0.15 -0.0105 -0.0471 3554154 ACon1_001179 CCC(C)c1cnc(Cc2ccccc2)c(=O)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L02 compound treatment 144240.0 -14600.0 -0.45 156960.0 6750.0 0.18 -0.1963 -0.404 3557616 ACon1_001180 COc1cc(cc(OC)c1O)C2C(COC3OCC(O)C(O)C3O)C(CO)Cc4cc(OC)c(O)c(OC)c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L03 compound treatment 149480.0 -9380.0 -0.29 157200.0 6990.0 0.18 -0.0771 -0.2248 3554516 ACon1_001181 CO[C@H]1C(=O)Nc2ccc(/C=C/C3(C)CCC(C)(C)CO3)c(O)c2[C@]1(O)c4ccc(OC)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L04 compound treatment 159560.0 697.0 0.02 142880.0 -7330.0 -0.19 -0.1193 -0.6228 3559072 ACon1_001182 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](OC(=O)/C=C/c4ccc(O)cc4)[C@@H](O)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L05 compound treatment 97600.0 -61300.0 -1.9 74600.0 -75600.0 -1.96 -2.7313 -0.9999 3557828 ACon1_001183 Oc1ccc(CCCCC(=O)CCc2ccc(O)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L06 compound treatment 13840.0 -145000.0 -4.49 12920.0 -137000.0 -3.57 -5.6996 -0.9935 2095398 ACon1_001184 CC(=CCCC1(C)Oc2ccc3c4cc(C)c(O)cc4[nH]c3c2C=C1)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L07 mock treatment 154680.0 -4180.0 -0.13 142840.0 -7370.0 -0.19 -0.227 -0.982 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L08 mock treatment 164560.0 5700.0 0.18 141760.0 -8450.0 -0.22 -0.0303 -0.1077 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L09 compound treatment 167040.0 8180.0 0.25 137320.0 -12900.0 -0.33 -0.0576 -0.1371 3558935 ACon1_001185 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L10 compound treatment 185280.0 26400.0 0.82 149200.0 -1010.0 -0.03 0.5603 0.6842 3558649 ACon1_001186 CC1=CCC2C(C)(C)CCC[C@]2(C)[C@]31CC[C@](C)(CC(=O)O)O3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L11 compound treatment 195680.0 36800.0 1.14 157240.0 7030.0 0.18 0.9359 0.8101 3557542 ACon1_001187 Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)c(C4C(Oc5cc(O)cc(O)c5C4=O)c6ccc(O)c(O)c6)c3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L12 compound treatment 199240.0 40400.0 1.25 179360.0 29200.0 0.76 1.4203 0.9711 3558613 ACon1_001188 OC[C@H]1O[C@@H](OCCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L13 compound treatment 62880.0 -96000.0 -2.97 60160.0 -90000.0 -2.34 -3.7573 -0.9929 3558939 ACon1_001189 CC(=O)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L14 compound treatment 15120.0 -144000.0 -4.45 14920.0 -135000.0 -3.52 -5.6349 -0.9931 3558993 ACon1_001190 CCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L15 mock treatment 166040.0 7180.0 0.22 144320.0 -5890.0 -0.15 0.0491 0.182 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L16 mock treatment 150400.0 -8460.0 -0.26 149800.0 -406.0 -0.01 -0.1929 -0.7349 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L17 compound treatment 194720.0 35900.0 1.11 183920.0 33700.0 0.88 1.405 0.9931 3559131 ACon1_001191 C[C@@]1(CCC[C@@]2(C)C3CCC4CC3(C[C@@]4(O)CO)CCC12)C(=O)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L18 compound treatment 235360.0 76500.0 2.37 159520.0 9310.0 0.24 1.8471 0.7753 3559237 ACon1_001192 O[C@H]1[C@@H](Oc2c([C@H]3[C@@H](Oc4cc(O)cc(O)c4C3=O)c5ccc(O)cc5)c(O)cc(O)c2C1=O)c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L19 compound treatment 87040.0 -71800.0 -2.23 87840.0 -62400.0 -1.62 -2.7194 -0.9879 3559639 ACon1_001193 CC(=O)/C=C(\O)/C=C/c1ccc(O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L20 compound treatment 130720.0 -28100.0 -0.87 140120.0 -10100.0 -0.26 -0.8019 -0.8807 3554658 ACon1_001194 COC(=O)C1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(=C1c3ccc(O)c(O)c3)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L21 compound treatment 151960.0 -6900.0 -0.21 149200.0 -1010.0 -0.03 -0.1697 -0.7876 3557983 ACon1_001195 CC1CCC2C1C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L22 compound treatment 133040.0 -25800.0 -0.8 148000.0 -2210.0 -0.06 -0.6063 -0.7558 3554257 ACon1_001196 CCCCC[C@@H]1OC2=C([C@H](O)[C@]1(C)O)C(=O)N(OC)C2=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L23 mock treatment 155800.0 -3060.0 -0.09 148520.0 -1690.0 -0.04 -0.0981 -0.9383 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 L24 mock treatment 148840.0 -10000.0 -0.31 154320.0 4110.0 0.11 -0.144 -0.4384 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M01 compound treatment 116640.0 -42200.0 -1.31 113000.0 -37200.0 -0.97 -1.6086 -0.9889 2110684 ACon1_001197 COC(=O)[C@]12C(=O)C(C)C(=O)[C@]2(C)C(=C[C@@H]3[C@]1(C)CC[C@@H]4C(C)(C)[C@H](CC[C@]43C=O)OC(=O)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M02 compound treatment 132960.0 -25900.0 -0.8 143480.0 -6730.0 -0.17 -0.6911 -0.8414 3558775 ACon1_001198 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)O)C2(C)C)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M03 compound treatment 142480.0 -16400.0 -0.51 138360.0 -11800.0 -0.31 -0.5766 -0.9713 3557303 ACon1_001199 COc1cc(O)cc2CC(C)OC(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M04 compound treatment 148880.0 -9980.0 -0.31 153080.0 2870.0 0.07 -0.1659 -0.5214 3558815 ACon1_001200 C[C@@H]1O[C@@H](O[C@@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@]2(C)CO)[C@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M05 compound treatment 113520.0 -45300.0 -1.4 71040.0 -79200.0 -2.06 -2.4479 -0.9827 3553725 ACon1_001201 CC(CO)C(=O)O[C@H]1C/C(=C/CC/C(=C/[C@H]2OC(=O)C(CN3CCCC3C(=O)O)[C@@H]21)/CO)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M06 compound treatment 168600.0 9740.0 0.3 167600.0 17400.0 0.45 0.5329 0.9807 3558829 ACon1_001202 CC1CCCC2=CC(OC2=O)C(C)(C)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M07 compound treatment 155160.0 -3700.0 -0.11 150560.0 354.0 0.01 -0.0746 -0.6483 3558899 ACon1_001203 CC(C)C(=O)OCC1(CO1)c2ccc(C)cc2OC(=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M08 compound treatment 162640.0 3780.0 0.12 146480.0 -3730.0 -0.1 0.0143 0.0942 3558868 ACon1_001204 CC(=O)CCCCCCCc1[nH]c2ccccc2c(=O)c1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M09 mock treatment 165040.0 6180.0 0.19 154520.0 4310.0 0.11 0.2146 0.9675 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M10 mock treatment 161160.0 2300.0 0.07 157320.0 7110.0 0.18 0.181 0.914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M11 compound treatment 15640.0 -143000.0 -4.44 14960.0 -135000.0 -3.51 -5.6227 -0.9933 3558753 ACon1_001205 CC(=CCc1c(oc2c3C=CC(C)(C)Oc3cc(O)c2c1=O)c4ccc(O)cc4O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M12 compound treatment 160280.0 1420.0 0.04 152040.0 1830.0 0.05 0.0648 0.9992 3558895 ACon1_001206 C[C@H]1O[C@@H](OC(C)(C)C2CCC(=CC2)C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M13 mock treatment 178000.0 19100.0 0.59 147880.0 -2330.0 -0.06 0.3766 0.6318 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M14 mock treatment 164560.0 5700.0 0.18 160720.0 10500.0 0.27 0.318 0.9777 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M15 compound treatment 169960.0 11100.0 0.34 155200.0 4990.0 0.13 0.3349 0.9112 3558864 ACon1_001207 C/C(=C\CC[C@@](C)(O)C=C)/C(=O)O[C@@H]1[C@@H]2O[C@]2(C)[C@H]3[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C[C@@]13OC(=O)\C(=C\CC[C@](C)(O)C=C)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M16 compound treatment 22440.0 -136000.0 -4.23 21560.0 -129000.0 -3.34 -5.3525 -0.9932 3558691 ACon1_001208 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)C(=C)CO)C1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M17 compound treatment 159720.0 857.0 0.03 144920.0 -5290.0 -0.14 -0.0783 -0.5599 3558897 ACon1_001209 CC(C)C(=O)OCC(O)(COC(=O)C(C)C)c1ccc(C)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M18 compound treatment 172280.0 13400.0 0.42 159280.0 9070.0 0.24 0.4607 0.9639 3558942 ACon1_001210 CC1=CCC(CC1)C(C)(C)O[C@@H]2O[C@H](COC(=O)c3cc(O)c(O)c(O)c3)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M19 compound treatment 9840.0 -149000.0 -4.62 10680.0 -140000.0 -3.63 -5.8284 -0.9928 3553659 ACon1_001211 CC(C)CCCC/C=C\CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M20 compound treatment 18280.0 -141000.0 -4.36 19840.0 -130000.0 -3.39 -5.4752 -0.9923 3558700 ACon1_001212 CC(=O)OC/C=C(\C)/CC/C=C(\C)/C(C/C=C(\CC/C=C(\C)/COC(=O)C)/C(=O)O)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M21 compound treatment 146920.0 -11900.0 -0.37 149680.0 -526.0 -0.01 -0.2713 -0.7327 3614729 ACon1_001213 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccc(O)cc6)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M22 compound treatment 10440.0 -148000.0 -4.6 10280.0 -140000.0 -3.64 -5.8226 -0.9932 3559009 ACon1_001214 CCCCCCCC/C=C\CCCCCCCc1cccc(O)c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M23 compound treatment 181800.0 22900.0 0.71 176560.0 26400.0 0.68 0.9867 0.9998 3558724 ACon1_001215 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](OC(=O)C)[C@@H](O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H]2OC(=O)/C=C/c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 M24 compound treatment 18200.0 -141000.0 -4.36 13960.0 -136000.0 -3.54 -5.585 -0.9947 3558423 ACon1_001216 C[C@]1(CCC[C@@]2(C)C3CCC4CC3(CC4=C)CCC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N01 compound treatment 59040.0 -99800.0 -3.09 61400.0 -88800.0 -2.31 -3.8186 -0.9896 1000005 ACon1_001217 CCCCCC(O)/C=C/C=C\CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N02 compound treatment 48800.0 -110000.0 -3.41 10760.0 -139000.0 -3.62 -4.9734 -0.9995 2119184 ACon1_001218 CC(=CCC/C(=C/Cc1cc2ccc(=O)oc2cc1O)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N03 compound treatment 155600.0 -3260.0 -0.1 162320.0 12100.0 0.31 0.1511 0.457 3553469 ACon1_001219 CC(C)(O)C1=CC23CC[C@H]4[C@@](C)(CCC[C@]4(C)C3C[C@@H]1OO2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N04 compound treatment 138960.0 -19900.0 -0.62 146360.0 -3850.0 -0.1 -0.5067 -0.8111 3614731 ACon1_001220 CC1=C[C@@H](O)[C@H]2C(C)(C)CCC[C@]2(C)[C@@]1(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N05 compound treatment 174560.0 15700.0 0.49 147400.0 -2810.0 -0.07 0.2924 0.5945 3558777 ACon1_001221 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(CC[C@]54C(=O)O)C(=O)O)C2(C)C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N06 compound treatment 159600.0 737.0 0.02 152080.0 1870.0 0.05 0.0506 0.9405 3559649 ACon1_001222 Oc1ccc(/C=C/C(=O)c2c(O)cc(O)cc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N07 compound treatment 158200.0 -663.0 -0.02 145160.0 -5050.0 -0.13 -0.1072 -0.808 3553701 ACon1_001223 CC(CCC=C(C)C)C1CC(O)C(C)(O)C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N08 compound treatment 171280.0 12400.0 0.38 158800.0 8590.0 0.22 0.43 0.9665 3557653 ACon1_001224 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N09 mock treatment 156760.0 -2100.0 -0.07 125600.0 -24600.0 -0.64 -0.4981 -0.7751 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N10 mock treatment 139640.0 -19200.0 -0.6 157280.0 7070.0 0.18 -0.2912 -0.4671 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N11 compound treatment 108520.0 -50300.0 -1.56 101600.0 -48600.0 -1.26 -1.996 -0.9945 3559029 ACon1_001225 CC(C)(O)CCC(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)C3CC=C4C(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N12 compound treatment 158640.0 -223.0 -0.01 145320.0 -4890.0 -0.13 -0.0946 -0.7444 1077975 ACon1_001226 COc1cc(CCC(=O)O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N13 mock treatment 156720.0 -2140.0 -0.07 133120.0 -17100.0 -0.44 -0.3609 -0.8039 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N14 mock treatment 158520.0 -343.0 -0.01 146320.0 -3890.0 -0.1 -0.0789 -0.7772 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N15 compound treatment 162440.0 3580.0 0.11 148400.0 -1810.0 -0.05 0.0452 0.3756 2060475 ACon1_001227 COc1cc(OC)c2C(=O)CC(Oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N16 compound treatment 208120.0 49300.0 1.53 172160.0 22000.0 0.57 1.4826 0.9099 3558625 ACon1_001228 COc1c(O)cc(cc1O)c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N17 compound treatment 170880.0 12000.0 0.37 150560.0 354.0 0.01 0.2698 0.7244 3559125 ACon1_001229 COc1ccc(cc1OC)C2OCC3[C@@H](OCC23)c4ccc(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N18 compound treatment 158080.0 -783.0 -0.02 150560.0 354.0 0.01 -0.0106 -0.41 3559207 ACon1_001230 CC1(C)C(O)CCC2(C)C3CCC4CC3(CCC12)C=C4CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N19 compound treatment 31880.0 -127000.0 -3.93 49440.0 -101000.0 -2.62 -4.6334 -0.9804 3559663 ACon1_001231 CC(=CCc1c(O)cc(O)c(C(=O)/C=C/c2ccc(O)cc2)c1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N20 compound treatment 80800.0 -78100.0 -2.42 91080.0 -59100.0 -1.54 -2.7966 -0.976 3559567 ACon1_001232 COC(=O)[C@]1(C)CCC[C@]2(C)[C@@H](CCc3ccoc3)C(=CC[C@@H]12)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N21 compound treatment 148000.0 -10900.0 -0.34 142400.0 -7810.0 -0.2 -0.3814 -0.9706 3558313 ACon1_001233 COc1cc(/C=C/C(=O)NCCc2ccc(O)cc2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N22 compound treatment 9760.0 -149000.0 -4.62 30760.0 -119000.0 -3.1 -5.4613 -0.9813 3554671 ACon1_001234 COC(=O)C1=C2C(Oc3cc(CO)cc(O)c3C2=O)C(O)C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N23 compound treatment 110520.0 -48300.0 -1.5 129640.0 -20600.0 -0.53 -1.437 -0.9036 3558632 ACon1_001235 C/C=C(\C)/C(=O)OC(C)(C)C1Cc2cc3ccc(=O)oc3cc2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 N24 compound treatment 125320.0 -33500.0 -1.04 112760.0 -37400.0 -0.97 -1.4229 -0.9995 3559148 ACon1_001236 OCC1OC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)C(O[C@H]5OC[C@](O)(CO)[C@H]5O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O01 compound treatment 100880.0 -58000.0 -1.8 92280.0 -57900.0 -1.51 -2.3346 -0.9961 3559908 ACon1_001237 CC1(CO)Oc2cc(O)c3c(=O)c(coc3c2C=C1)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O02 compound treatment 140160.0 -18700.0 -0.58 130720.0 -19500.0 -0.51 -0.7678 -0.9977 3558779 ACon1_001238 C[C@H](C[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O03 compound treatment 149720.0 -9140.0 -0.28 150160.0 -45.6 0.0 -0.2011 -0.7101 3553208 ACon1_001239 CC(=O)c1cc(C)c(O)c(COC2OC(CO)C(O)C(O)C2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O04 compound treatment 155480.0 -3380.0 -0.1 150120.0 -85.6 0.0 -0.0757 -0.722 3558817 ACon1_001240 C[C@@H]1O[C@@H](O[C@@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@]2(C)CO)[C@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O05 compound treatment 132400.0 -26500.0 -0.82 119880.0 -30300.0 -0.79 -1.1369 -0.9998 3558838 ACon1_001241 COc1cc(CCC(O)CC(=O)CCc2ccccc2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O06 compound treatment 34240.0 -125000.0 -3.86 22840.0 -127000.0 -3.31 -5.0704 -0.997 3558830 ACon1_001242 CC(=O)OC1/C=C(/CCC=C(C)C(=O)C=CC1(C)C)\C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O07 compound treatment 165360.0 6500.0 0.2 163320.0 13100.0 0.34 0.3833 0.9685 3554193 ACon1_001243 CCC[C@H]1C[C@H]2OC(=O)c3c(O)c(OC)c(OC)cc3[C@H]2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O08 compound treatment 187240.0 28400.0 0.88 193160.0 43000.0 1.12 1.4109 0.993 3558870 ACon1_001244 CC(=O)CCCCCCCc1cc(=O)c2ccccc2[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O09 compound treatment 172240.0 13400.0 0.41 159000.0 8790.0 0.23 0.4547 0.9606 3614735 ACon1_001245 OC[C@H]1O[C@@H](Oc2ccc(/C=C/c3cc(O)cc(O)c3)cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O10 compound treatment 170920.0 12100.0 0.37 155520.0 5310.0 0.14 0.3618 0.9084 3558880 ACon1_001246 CC1OC(OC2C(O)C(O)C(OC2Oc3cc(O)c4c(=O)cc(oc4c3)c5ccc(O)c(O)c5)C(=O)O)C(O)C(O)C1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O11 mock treatment 136800.0 -22100.0 -0.68 146840.0 -3370.0 -0.09 -0.5452 -0.7911 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O12 mock treatment 161760.0 2900.0 0.09 146960.0 -3250.0 -0.08 0.0038 0.0313 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O13 compound treatment 71960.0 -86900.0 -2.69 44120.0 -106000.0 -2.76 -3.853 -0.9999 3558794 ACon1_001247 CCCCCCCCCCCC(O)CC(=O)OCC(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O14 compound treatment 150960.0 -7900.0 -0.24 148520.0 -1690.0 -0.04 -0.2041 -0.8206 3555946 ACon1_001248 OC1CCC(O)(C(=O)O)C1(O)C(=O)OCc2cc(O)ccc2OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O15 compound treatment 188120.0 29300.0 0.91 161360.0 11200.0 0.29 0.8459 0.8889 3558871 ACon1_001249 CC(=O)c1c(O)cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O16 compound treatment 13680.0 -145000.0 -4.5 12960.0 -137000.0 -3.57 -5.7024 -0.9934 3558697 ACon1_001250 COC(=O)/C/1=C/CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3[C@@H](OC(=O)/C(=C/C)/C)C1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O17 compound treatment 166280.0 7420.0 0.23 148000.0 -2210.0 -0.06 0.122 0.515 3558900 ACon1_001251 CCC(C)C(=O)OCC1(CO1)c2ccc(C)cc2OC(=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O18 compound treatment 209280.0 50400.0 1.56 185640.0 35400.0 0.92 1.7556 0.9682 3557674 ACon1_001252 OC1COC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O19 compound treatment 164480.0 5620.0 0.17 158720.0 8510.0 0.22 0.2795 0.993 3558944 ACon1_001253 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O20 compound treatment 175200.0 16300.0 0.51 148720.0 -1490.0 -0.04 0.3306 0.6513 3559017 ACon1_001254 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O21 compound treatment 168360.0 9500.0 0.29 159080.0 8870.0 0.23 0.3711 0.9927 3555821 ACon1_001255 OC(=O)C(CCCCCCOC(=O)C(=O)OCCCCCCC(C(=O)O)C(=C)C(=O)O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O22 compound treatment 8360.0 -151000.0 -4.66 9800.0 -140000.0 -3.65 -5.877 -0.9926 3559011 ACon1_001256 CCCCCCCCCC/C=C\CCCCCCCc1cccc(O)c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O23 compound treatment 161760.0 2900.0 0.09 148600.0 -1610.0 -0.04 0.034 0.3433 3558726 ACon1_001257 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2c3c(O)cc(O)c4c(=O)cc(oc34)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 O24 compound treatment 152520.0 -6340.0 -0.2 151600.0 1390.0 0.04 -0.1133 -0.5672 3557891 ACon1_001258 OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)CC(Oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P01 compound treatment 76720.0 -82100.0 -2.55 67440.0 -82800.0 -2.15 -3.3203 -0.9965 1104287 ACon1_001259 CCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P02 compound treatment 36480.0 -122000.0 -3.79 32200.0 -118000.0 -3.07 -4.8494 -0.9944 3559023 ACon1_001260 CC(=C)C(=O)OC1CC(CO)CCC/C(=C/C2OC(=O)C(=C)C21)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P03 compound treatment 148320.0 -10500.0 -0.33 134520.0 -15700.0 -0.41 -0.5192 -0.994 3558101 ACon1_001261 COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P04 compound treatment 176000.0 17100.0 0.53 159880.0 9670.0 0.25 0.5532 0.9417 3554885 ACon1_001262 COc1cc(ccc1O)C2Oc3c(C2CO)c(ccc3O)[C@@H]4Oc5cc(O)cc(O)c5C(=O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P05 compound treatment 133320.0 -25500.0 -0.79 142200.0 -8010.0 -0.21 -0.7067 -0.8636 1034727 ACon1_001263 COc1ccc(cc1)c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P06 compound treatment 141600.0 -17300.0 -0.53 138520.0 -11700.0 -0.3 -0.5929 -0.964 3559423 ACon1_001264 OCC(Cc1ccc2OCOc2c1)C(CO)Cc3ccc4OCOc4c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P07 compound treatment 164280.0 5420.0 0.17 165600.0 15400.0 0.4 0.4015 0.9256 1096015 ACon1_001265 CC12CC(O)CC(C)(C)C2=CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P08 compound treatment 157400.0 -1460.0 -0.05 135080.0 -15100.0 -0.39 -0.3099 -0.7835 1115322 ACon1_001266 COc1ccn(C)c(=O)c1C#N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P09 compound treatment 151440.0 -7420.0 -0.23 200080.0 49900.0 1.3 0.7537 0.5727 3558968 ACon1_001267 O[C@@H]1Cc2c(O)cc3O[C@]4(Oc5cc(O)cc(O)c5[C@H]([C@H]4O)c3c2O[C@@H]1c6ccc(O)c(O)c6)c7ccc(O)cc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P10 compound treatment 17520.0 -141000.0 -4.38 16240.0 -134000.0 -3.48 -5.558 -0.9935 288 ACon1_001268 C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P11 mock treatment 160240.0 1380.0 0.04 158800.0 8590.0 0.22 0.1881 0.8273 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P12 mock treatment 163600.0 4740.0 0.15 126320.0 -23900.0 -0.62 -0.335 -0.5254 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P13 compound treatment 94120.0 -64700.0 -2.01 93760.0 -56400.0 -1.47 -2.4555 -0.9882 3558980 ACon1_001269 C/C(=C\C(=O)O)/CCC1C(=C)CCC2C(C)(CO)CCCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P14 compound treatment 8400.0 -150000.0 -4.66 7480.0 -143000.0 -3.71 -5.9188 -0.9936 3558996 ACon1_001270 CCCCCCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P15 compound treatment 10360.0 -149000.0 -4.6 8800.0 -141000.0 -3.67 -5.8516 -0.9938 3555936 ACon1_001271 Oc1ccc(/C=C/c2cc3O[C@H]([C@@H](c3c(O)c2)c4cc5O[C@@H]([C@H](c5c(O)c4)c6cc(O)cc(O)c6)c7ccc(O)c(O)c7)c8ccc(O)cc8)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P16 compound treatment 162640.0 3780.0 0.12 151240.0 1030.0 0.03 0.1018 0.8474 3559197 ACon1_001272 CO/C(=C\1/OC(=O)C=C1OC)/[C@@H]2O[C@H]2c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P17 compound treatment 171480.0 12600.0 0.39 154200.0 3990.0 0.1 0.3498 0.8649 3559114 ACon1_001273 COc1ccc(cc1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc5OCOc5c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P18 compound treatment 178640.0 19800.0 0.61 163000.0 12800.0 0.33 0.6684 0.9587 1025510 ACon1_001274 COc1ccc(cc1OC)C2OCC3(O)C(OCC23)c4ccc(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P19 compound treatment 33920.0 -125000.0 -3.87 35760.0 -114000.0 -2.97 -4.8401 -0.9915 2141039 ACon1_001275 CO[C@H]1C[C@H](O[C@H]2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P20 compound treatment 150160.0 -8700.0 -0.27 145360.0 -4850.0 -0.13 -0.2797 -0.9399 3552212 ACon1_001276 C[C@@H]([C@@H]1CC[C@@](C)(O1)C=C)C(=O)CC=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P21 compound treatment 48920.0 -110000.0 -3.41 36760.0 -113000.0 -2.95 -4.4931 -0.9974 3552101 ACon1_001277 C/C=C/C=C/C=C/C(=O)O[C@@H]1C=C2COC(=O)[C@]2(O)[C@@]3(C)CCCC(C)(C)[C@H]13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P22 compound treatment 38160.0 -121000.0 -3.74 56880.0 -93300.0 -2.42 -4.3591 -0.978 3558924 ACon1_001278 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)C(CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P23 compound treatment 104600.0 -54300.0 -1.68 123040.0 -27200.0 -0.71 -1.688 -0.9257 3557752 ACon1_001279 OCC1OC(Oc2cc(O)c3C(=O)C(O)C(Oc3c2)c4ccc(O)cc4)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2293 P24 compound treatment 76440.0 -82400.0 -2.55 77000.0 -73200.0 -1.9 -3.1508 -0.9895 1102176 ACon1_001280 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C=CC3(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A01 compound treatment 17840.0 -50700.0 -1.57 17560.0 -82400.0 -2.14 -2.626 -0.9885 3555976 ACon1_001281 ON1CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A02 compound treatment 45320.0 -23300.0 -0.72 64880.0 -35100.0 -0.91 -1.1545 -0.9932 3557285 ACon1_001282 COC(=O)[C@]12Oc3cc(C)c(c(O)c3C(=O)C2=C(O)CC[C@@H]1O)c4ccc(O)c5C(=O)C6=C(O)C[C@H](C)[C@H](OC(=O)C)[C@@]6(Oc45)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A03 compound treatment 3600.0 -65000.0 -2.01 5000.0 -95000.0 -2.47 -3.1687 -0.9949 3554124 ACon1_001283 CCC(C)[C@@H]1N(C)C(=O)[C@H](OC(=O)[C@H](C(C)CC)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)CC)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A04 compound treatment 45480.0 -23100.0 -0.72 61600.0 -38400.0 -1.0 -1.2113 -0.9868 3558541 ACon1_001284 OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC=C3[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A05 compound treatment 21880.0 -46700.0 -1.45 27520.0 -72500.0 -1.88 -2.3545 -0.9916 3559091 ACon1_001285 OC1[C@H](OC(=O)c2cc(O)c(O)c(O)c2)OC3COC(=O)c4cc(O)c(O)c(O)c4-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]1[C@@H]3OC(=O)c6cc(O)c(O)c(O)c6c7c(O)c(O)c(O)cc7C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A06 compound treatment 58440.0 -10100.0 -0.31 75160.0 -24800.0 -0.64 -0.6782 -0.9455 3559109 ACon1_001286 COc1c(O)c(O)cc2ccc3cccc(O)c3c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A07 compound treatment 40320.0 -28300.0 -0.88 66160.0 -33800.0 -0.88 -1.2405 -1.0 3557604 ACon1_001287 COc1cc(O[C@@H]2O[C@H](COC3OCC(O)C(O)C3O)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A08 compound treatment 42760.0 -25800.0 -0.8 57880.0 -42100.0 -1.09 -1.3392 -0.9882 3559066 ACon1_001288 OC[C@H]1O[C@@H](Oc2ccc(COC(=O)CC(O)(CC(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3)C(=O)OCc5ccc(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)cc5)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A09 compound treatment 42680.0 -25900.0 -0.8 70840.0 -29100.0 -0.76 -1.1028 -0.9996 3559055 ACon1_001289 C[C@@H]1O[C@@H](O[C@@H]2C=C(CO)[C@@H]3[C@H]2C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H](O)[C@H]1OC(=O)/C=C/c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A10 compound treatment 4280.0 -64300.0 -1.99 6240.0 -93700.0 -2.44 -3.131 -0.995 3559247 ACon1_001290 COc1c(C)c(O)c(C)c(O)c1C(=O)CCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A11 compound treatment 47160.0 -21400.0 -0.66 64920.0 -35100.0 -0.91 -1.1135 -0.9879 3552701 ACon1_001291 C[C@@H]1CC[C@]2(C)[C@@]3(C)CC[C@@]2(OC3=O)[C@]41C[C@@H](OC4=O)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A12 compound treatment 45440.0 -23100.0 -0.72 67920.0 -32100.0 -0.83 -1.096 -0.9972 3559273 ACon1_001292 COC(=O)[C@H](OC(=O)C)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CC[C@@H](C3=C)[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A13 mock treatment 42680.0 -25900.0 -0.8 71720.0 -28300.0 -0.73 -1.0867 -0.999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A14 mock treatment 48160.0 -20400.0 -0.63 88120.0 -11900.0 -0.31 -0.6653 -0.9452 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A15 compound treatment 45560.0 -23000.0 -0.71 74760.0 -25200.0 -0.66 -0.9677 -0.9991 2097145 ACon1_001293 COc1c(ccc2Oc3c(O)cc(C)cc3COC(=O)c12)C(CC(C)C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A16 compound treatment 8200.0 -60400.0 -1.87 9040.0 -90900.0 -2.36 -2.9937 -0.9933 3559137 ACon1_001294 O=C(CCc1ccccc1)/C=C/CCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A17 compound treatment 46080.0 -22500.0 -0.7 81760.0 -18200.0 -0.47 -0.8277 -0.9822 3552685 ACon1_001295 C[C@@H]1CC(=O)C2=C(C1)C[C@@H](O)[C@]3(O)[C@@H](O)c4c(O)cccc4C(=O)C23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A18 compound treatment 13840.0 -54700.0 -1.7 23120.0 -76900.0 -2.0 -2.6115 -0.9967 3559173 ACon1_001296 COc1cc(OC)c(cc1OC)C(O)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A19 compound treatment 55200.0 -13400.0 -0.41 98160.0 -1810.0 -0.05 -0.3266 -0.7823 3189183 ACon1_001297 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]3NC(=N)N)O[C@@H](C)[C@]2(O)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A20 compound treatment 51880.0 -16700.0 -0.52 76040.0 -23900.0 -0.62 -0.8057 -0.9958 3559107 ACon1_001298 CC1(C)[C@H](O)[C@H](O)C[C@]2(C)[C@H]3CCC(C)(C=C3CCC12)C(=O)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A21 compound treatment 39440.0 -29100.0 -0.9 43680.0 -56300.0 -1.46 -1.6728 -0.9732 3557672 ACon1_001299 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4cc(O)c(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A22 compound treatment 52680.0 -15900.0 -0.49 84560.0 -15400.0 -0.4 -0.6317 -0.9947 3559201 ACon1_001300 COc1cc(cc(OC)c1OC)C2OCC3C(OCC23)c4cc(OC)c(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A23 compound treatment 92680.0 24100.0 0.75 126600.0 26600.0 0.69 1.0171 0.9993 2089505 ACon1_001301 Cc1cc(O)cc2oc(=O)c3c(O)cc(O)cc3c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 A24 compound treatment 44360.0 -24200.0 -0.75 54800.0 -45200.0 -1.17 -1.3607 -0.9767 3557367 ACon1_001302 CC(=O)O[C@@H]1C[C@@]2(C)[C@]3(CO3)[C@@H]1O[C@@H]4C=C(C)C(O)C[C@@]42C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B01 compound treatment 57040.0 -11500.0 -0.36 70440.0 -29500.0 -0.77 -0.7956 -0.9397 3553926 ACon1_001303 CC1=CC(=O)[C@H]2C(C)(C)CCC[C@]2(C)[C@@]1(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B02 compound treatment 3320.0 -65300.0 -2.02 4880.0 -95100.0 -2.47 -3.1771 -0.9951 3614774 ACon1_001304 CCCC(O)c1c(O)cccc1C(=O)CC(O)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B03 compound treatment 104840.0 36300.0 1.12 164120.0 64100.0 1.67 1.9728 0.9816 3553162 ACon1_001305 C[C@H]1OC(=O)c2c(O)c(C(=O)O)c(O)c(C)c2[C@@H]1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B04 compound treatment 56240.0 -12300.0 -0.38 73600.0 -26400.0 -0.69 -0.755 -0.9621 3614776 ACon1_001306 COc1ccc(/C=C/c2cc(OC)cc3OC(C)(C)CCc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B05 compound treatment 5400.0 -63200.0 -1.96 7280.0 -92700.0 -2.41 -3.0874 -0.9947 3614779 ACon1_001307 C/C=C(/C)\C(=O)O[C@H]1[C@H](OC(=O)/C(=C\C)/C)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(OC7OC(C)C(O)C(OC8OC(CO)C(O)C(O)C8O)C7O)C6O)C(=O)O)C(C)(C)C5CC[C@]43C)[C@@H]2CC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B06 compound treatment 85840.0 17300.0 0.53 142800.0 42800.0 1.11 1.1649 0.9436 1032451 ACon1_001308 CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B07 compound treatment 79400.0 10800.0 0.34 98960.0 -1010.0 -0.03 0.2183 0.6496 3614784 ACon1_001309 CC(C)C1=C(O)C(=O)C2=C([C@@H](CC3C(C)(C)CCC[C@@]32CO)OC(=O)C)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B08 compound treatment 86880.0 18300.0 0.57 145640.0 45700.0 1.19 1.2398 0.9428 3614787 ACon1_001310 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]([C@H](C)OC(=O)C)[C@@H]1CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B09 compound treatment 85560.0 17000.0 0.53 138560.0 38600.0 1.0 1.0808 0.9546 3614791 ACon1_001311 CCC(C)CCC(O)C1=C(C)C(O)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B10 compound treatment 33360.0 -35200.0 -1.09 39440.0 -60500.0 -1.57 -1.8839 -0.9841 3554503 ACon1_001312 CO[C@@H]1[C@@H](O)[C@H](C)O[C@@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)[C@@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B11 compound treatment 53320.0 -15300.0 -0.47 45800.0 -54200.0 -1.41 -1.3298 -0.8955 3614794 ACon1_001313 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B12 compound treatment 77080.0 8490.0 0.26 124840.0 24900.0 0.65 0.643 0.9216 3614796 ACon1_001314 COc1c(C)c(OC/C=C(\C)/C(=O)OCC(O)C(O)C(O)C(O)CO)cc(CO)c1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B13 mock treatment 78720.0 10100.0 0.31 125240.0 25300.0 0.66 0.6862 0.943 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B14 mock treatment 86880.0 18300.0 0.57 133440.0 33500.0 0.87 1.0157 0.9785 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B15 compound treatment 27800.0 -40800.0 -1.26 37800.0 -62200.0 -1.62 -2.0359 -0.9926 3614799 ACon1_001315 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(CO)[C@@H](CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B16 compound treatment 76880.0 8290.0 0.26 150840.0 50900.0 1.32 1.1163 0.829 3614803 ACon1_001316 CCN1C[C@]2(C)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@@](C[C@@H]5OC)(OC)C6[C@@H](O)C32)[C@@H]61 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B17 compound treatment 5480.0 -63100.0 -1.96 9760.0 -90200.0 -2.34 -3.0401 -0.9959 3614807 ACon1_001317 COc1cc(c(OC)c2oc3cc(O)c(O)cc3c12)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B18 compound treatment 74320.0 5730.0 0.18 125520.0 25500.0 0.66 0.595 0.8659 3614809 ACon1_001318 COc1ccc2nccc(C(O)C3CC4CC[N+]3([O-])CC4C=C)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B19 compound treatment 74840.0 6250.0 0.19 124920.0 24900.0 0.65 0.5953 0.88 3614812 ACon1_001319 CC1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(CCC6(CCC54C)C(=O)OC7OC(CO)C(O)C(O)C7O)C(=O)O)C2(C)CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B20 compound treatment 67920.0 -668.0 -0.02 126800.0 26800.0 0.7 0.4783 0.6858 3614813 ACon1_001320 CCN1C[C@]2(COC)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](OC)[C@@H]4[C@](O)(C[C@@H]5OC)[C@]6(O)CC32)[C@H]16 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B21 compound treatment 7320.0 -61300.0 -1.9 9960.0 -90000.0 -2.34 -2.9961 -0.9946 3558920 ACon1_001321 Oc1cc(cc(O)c1O)C(=O)O[C@@H]2O[C@@H]3COC(=O)c4cc(O)c(O)c(O)c4-c5c(O)c(O)c(O)cc5C(=O)O[C@H]3[C@H](OC(=O)c6cc(O)c(O)c(O)c6)[C@H]2OC(=O)c7cc(O)c(O)c(O)c7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B22 compound treatment 60440.0 -8150.0 -0.25 93280.0 -6690.0 -0.17 -0.3015 -0.9834 1099690 ACon1_001322 COC(=O)C12CC3CC(C(C)O)C2N(C3)CCc4c1[nH]c5ccc(OC)cc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B23 compound treatment 63160.0 -5430.0 -0.17 87760.0 -12200.0 -0.32 -0.3433 -0.9559 3614819 ACon1_001323 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@H](O)[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O[C@@H]7OC[C@H](O)[C@H](O)[C@H]7O)[C@H]6O)C(=O)O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]8OC[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 B24 compound treatment 52200.0 -16400.0 -0.51 75200.0 -24800.0 -0.64 -0.8142 -0.9931 3614822 ACon1_001324 COc1cc2CCN(C)C3(Cc4ccc5OCOc5c4C3O)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C01 compound treatment 8440.0 -60100.0 -1.86 8680.0 -91300.0 -2.37 -2.9951 -0.9929 3180147 ACon1_001325 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(O)c(OC)cc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C02 compound treatment 7000.0 -61600.0 -1.91 10560.0 -89400.0 -2.32 -2.9921 -0.9952 3558915 ACon1_001326 Oc1ccc(cc1)C2Oc3cc(O)cc(O)c3C(=O)C2C4C(Oc5cc(O)cc(O)c5C4=O)c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C03 compound treatment 48480.0 -20100.0 -0.62 71040.0 -28900.0 -0.75 -0.9721 -0.9956 3559041 ACon1_001327 COc1ccc(/C=C/C(=O)O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C04 compound treatment 69160.0 573.0 0.02 86200.0 -13800.0 -0.36 -0.2405 -0.6712 3559084 ACon1_001328 OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c(C(=O)c3ccc(O)cc3)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C05 compound treatment 66600.0 -1990.0 -0.06 115320.0 15300.0 0.4 0.2384 0.5909 3554661 ACon1_001329 COC(=O)C1(Cc2ccc(O)cc2)OC(=O)C(=C1c3ccc(O)cc3)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C06 compound treatment 56600.0 -12000.0 -0.37 101600.0 1630.0 0.04 -0.2327 -0.6226 3558716 ACon1_001330 COc1cc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)ccc1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C07 compound treatment 20640.0 -47900.0 -1.49 37160.0 -62800.0 -1.63 -2.2045 -0.9989 3552084 ACon1_001331 C/C=C/C=C/C(=O)N1CC[C@]23[C@@H]1N4CC[C@]3([C@H]5Nc6ccccc62)c7c(cccc7[C@@H]4C8OC8(C)C)N5C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C08 compound treatment 66200.0 -2390.0 -0.07 121280.0 21300.0 0.55 0.3392 0.6072 3559229 ACon1_001332 OC[C@H]1O[C@@H](Oc2ccc(cc2)c3cc(=O)c4c(O)cc(O)cc4o3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C09 compound treatment 39560.0 -29000.0 -0.9 58560.0 -41400.0 -1.08 -1.3968 -0.996 3559102 ACon1_001333 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C3(C)C)O[C@@H]([C@H]2O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C10 compound treatment 20240.0 -48300.0 -1.5 26960.0 -73000.0 -1.9 -2.4007 -0.9932 3559180 ACon1_001334 C[C@@H]1O[C@@H](O[C@H]2[C@@H](O)[C@@H](C)O[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5C=CC7=C8CC(C)(C)CC[C@]8(CO)CC[C@]76C)[C@]4(C)CO)O[C@@H]3CO)[C@@H]2O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C11 mock treatment 55200.0 -13400.0 -0.41 109360.0 9390.0 0.24 -0.1208 -0.2511 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C12 mock treatment 56600.0 -12000.0 -0.37 98080.0 -1890.0 -0.05 -0.2974 -0.7938 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C13 compound treatment 54720.0 -13900.0 -0.43 75920.0 -24100.0 -0.62 -0.7457 -0.9833 3558601 ACon1_001335 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)OC6OCC(OC7OCC(O)C(O)C7O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C14 compound treatment 51040.0 -17500.0 -0.54 107080.0 7110.0 0.18 -0.2539 -0.4421 3557383 ACon1_001336 CO[C@H]1C(O[C@@H]2C[C@H]3O[C@@H]([C@@H](O)[C@H](OC(=O)/C(=C/C)/CO)[C@]3(O)O[C@H]12)C(=O)OC)n4cnc5c(N)ncnc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C15 mock treatment 52960.0 -15600.0 -0.48 102240.0 2270.0 0.06 -0.3007 -0.6165 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C16 mock treatment 57600.0 -11000.0 -0.34 113560.0 13600.0 0.35 0.0089 0.0182 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C17 compound treatment 35560.0 -33000.0 -1.02 58560.0 -41400.0 -1.08 -1.4845 -0.9997 3555977 ACon1_001337 ON1CCCCCNC(=O)CCC(=O)N(O)CCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C18 compound treatment 70280.0 1690.0 0.05 122280.0 22300.0 0.58 0.4469 0.7679 3559187 ACon1_001338 CC(C)C[C@@](O)(CC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C19 compound treatment 76720.0 8130.0 0.25 118040.0 18100.0 0.47 0.5101 0.9574 3614831 ACon1_001339 C[C@H]1O[C@@H](OC/2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(=O)O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)/C=C/C=C/CC\C=C\C=C\C=C\C=C2)[C@@H](O)[C@@H](N)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C20 compound treatment 81320.0 12700.0 0.39 137880.0 37900.0 0.98 0.9754 0.9193 3559183 ACon1_001340 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(=O)O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C21 compound treatment 5240.0 -63300.0 -1.96 8640.0 -91300.0 -2.37 -3.0659 -0.9956 3558289 ACon1_001341 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)O[C@@]%101CCC(C)CO%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C22 compound treatment 77040.0 8450.0 0.26 111360.0 11400.0 0.3 0.3944 0.9981 3559203 ACon1_001342 C[C@H]1[C@@H]2CC[C@]3(C)O[C@]4(C)C(O)[C@@H]5[C@H]6[C@H](C(=C7[C@@H]6C[C@@](C)(O)C[C@H]8[C@H](C)C(=O)O[C@@H]87)C)C4(C53)[C@H]2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C23 compound treatment 59280.0 -9310.0 -0.29 72920.0 -27100.0 -0.7 -0.7009 -0.9226 3554240 ACon1_001343 CCCCC/C=C\C/C=C\C(O)CCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 C24 compound treatment 47080.0 -21500.0 -0.67 67560.0 -32400.0 -0.84 -1.0667 -0.9933 3555026 ACon1_001344 COc1cc2[C@@H]3CCN4CC=C[C@]56CC[C@H]3[C@]64N(C(=O)C5)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D01 compound treatment 87680.0 19100.0 0.59 126120.0 26100.0 0.68 0.8987 0.9976 3553596 ACon1_001345 CC(C)C1NC(=O)/C(=C/c2c[nH]cn2)/NC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D02 compound treatment 91080.0 22500.0 0.7 89920.0 -10100.0 -0.26 0.3081 0.414 3614835 ACon1_001346 OCc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D03 compound treatment 102680.0 34100.0 1.06 159880.0 59900.0 1.56 1.8476 0.9822 3559559 ACon1_001347 C[C@@H]1C2[C@@H](CC(C)C(=O)C/C=C(\C)/C[C@@H]2O)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D04 compound treatment 15360.0 -53200.0 -1.65 20880.0 -79100.0 -2.06 -2.6193 -0.9941 3614837 ACon1_001348 C[C@H]1C2[C@H](CC3C4CC=C5C[C@@H](O)C[C@@H](O[C@@H]6OC[C@H](O)[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]8OC(=O)C)[C@]5(C)C4CC[C@]23C)O[C@]91OCC(=C)[C@H](OC%10OC(C)C(O)C(O)C%10O)[C@@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D05 compound treatment 129960.0 61400.0 1.9 176160.0 76200.0 1.98 2.7444 0.9998 3614840 ACon1_001349 OCc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D06 compound treatment 55640.0 -12900.0 -0.4 87880.0 -12100.0 -0.31 -0.5058 -0.9927 3614842 ACon1_001350 COc1cc(OC)c(CC=C(C)C)c(/C=C/c2ccc(OC)c(OC)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D07 compound treatment 83640.0 15100.0 0.47 118720.0 18700.0 0.49 0.6742 0.9998 1054271 ACon1_001351 COc1ccc(cc1O)c2cc(=O)c3c(O)c(OC)c(OC)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D08 compound treatment 107360.0 38800.0 1.2 137440.0 37500.0 0.97 1.5379 0.9946 3614846 ACon1_001352 CC/C=C/c1ccc(C)cc1\C=C\CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D09 compound treatment 109600.0 41000.0 1.27 169480.0 69500.0 1.81 2.1756 0.9852 3614849 ACon1_001353 OC[C@H]1O[C@@H](OC(=O)/C=C/c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D10 compound treatment 83720.0 15100.0 0.47 131000.0 31000.0 0.81 0.9016 0.9667 3614853 ACon1_001354 CCC(O)C(O)/C=C\C/C=C\CCCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D11 mock treatment 103320.0 34700.0 1.08 146360.0 46400.0 1.21 1.6132 0.9984 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D12 mock treatment 106440.0 37900.0 1.17 149040.0 49100.0 1.27 1.7308 0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D13 compound treatment 68560.0 -27.5 0.0 126120.0 26100.0 0.68 0.4798 0.7062 3614858 ACon1_001355 OC(=O)C(Cc1ccc(O)c(O)c1)OC(=O)C2C(C(C2c3ccc(O)c(O)c3)c4ccc(O)c(O)c4)C(=O)OC(Cc5ccc(O)c(O)c5)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D14 compound treatment 83040.0 14500.0 0.45 161960.0 62000.0 1.61 1.4555 0.8707 3614860 ACon1_001356 OC/C=C\1/CN2CC[C@]34[C@@H]2C[C@@H]1[C@@H]5[C@@H]4N(C(=O)CC5O)c6ccccc63 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D15 mock treatment 88120.0 19500.0 0.61 157480.0 57500.0 1.49 1.4845 0.9208 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D16 mock treatment 85960.0 17400.0 0.54 161840.0 61900.0 1.61 1.5173 0.895 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D17 compound treatment 82240.0 13700.0 0.42 116920.0 16900.0 0.44 0.6105 0.9998 3614863 ACon1_001357 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D18 compound treatment 108600.0 40000.0 1.24 150400.0 50400.0 1.31 1.8031 0.9996 1099692 ACon1_001358 CCC1C2N3CCC24C(=C(C1CC3)C(=O)OC)Nc5ccccc54 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D19 compound treatment 23320.0 -45300.0 -1.4 41400.0 -58600.0 -1.52 -2.0679 -0.9992 3614868 ACon1_001359 CCCCCCCCCC(O)C(C)C(O)C(CO)/C=C(\C)/C1=CC(=O)C(C)CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D20 compound treatment 85880.0 17300.0 0.54 134840.0 34900.0 0.91 1.0195 0.9686 3614872 ACon1_001360 CCC1CC2CC3(C1N(CCc4c3[nH]c5ccc(OC)cc45)C2=O)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D21 compound treatment 82400.0 13800.0 0.43 106520.0 6550.0 0.17 0.4229 0.9183 3614874 ACon1_001361 CC(C1CC(O)C(C)(C)O1)C2CC[C@@]3(C)C4CC[C@H]5C(C)C(CC[C@]65C[C@@]46CC[C@]23C)OC7OC(COC(=O)C)C(OC8OC(CO)C(OC9OC(CO)C(O)C(O)C9O)C(OC%10OC(C)C(O)C(O)C%10O)C8O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D22 compound treatment 72120.0 3530.0 0.11 115040.0 15100.0 0.39 0.3542 0.8714 3614877 ACon1_001362 CC(C)C(NC=O)C(=O)N1CCC2Oc3ccc(/C=C\NC(=O)C(Cc4ccccc4)NC(=O)C21)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D23 compound treatment 47080.0 -21500.0 -0.67 68600.0 -31400.0 -0.82 -1.0476 -0.995 3614881 ACon1_001363 CO[C@H]1[C@H](O)[C@@H](O)[C@H](OC2CC3C(=CC2(C)C=C)CCC4C(C)(C)C(CCC34C)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O)O[C@@H]1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 D24 compound treatment 51360.0 -17200.0 -0.53 82520.0 -17500.0 -0.45 -0.6981 -0.9967 3614885 ACon1_001364 COc1ccc2[nH]c3C4CC/5C(CO)C(Cc3c2c1)[N+]4([O-])C\C5=C\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E01 mock treatment 46560.0 -22000.0 -0.68 58240.0 -41700.0 -1.08 -1.2493 -0.9751 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E02 mock treatment 58080.0 -10500.0 -0.33 77880.0 -22100.0 -0.57 -0.6361 -0.9639 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E03 compound treatment 47080.0 -21500.0 -0.67 59400.0 -40600.0 -1.05 -1.2166 -0.9755 3559005 ACon1_001365 CC1OC(O[C@H]2[C@@H](C)O[C@@H](OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O[C@@H]%10O[C@H](CO)[C@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@@](C)(C=O)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](OC%11OC(CO)C(O)C(O)C%11O)[C@H]2O)C(O)C(O)C1OC%12OCC(O)C(O)C%12O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E04 compound treatment 74200.0 5610.0 0.17 91160.0 -8810.0 -0.23 -0.0389 -0.1354 3472823 ACon1_001366 COc1ccc(cc1)C(C)C(=O)c2ccc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E05 compound treatment 42680.0 -25900.0 -0.8 58440.0 -41500.0 -1.08 -1.3307 -0.9894 3554702 ACon1_001367 COC(=O)c1cc(O)cc(O)c1C(=O)c2c(O)c(Cl)c(C)c(Cl)c2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E06 compound treatment 49760.0 -18800.0 -0.58 67960.0 -32000.0 -0.83 -1.0006 -0.9849 3559119 ACon1_001368 O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(OC(=O)c4cc(O)c(O)c(O)c4)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E07 compound treatment 78040.0 9450.0 0.29 94800.0 -5170.0 -0.13 0.1121 0.3478 3558966 ACon1_001369 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E08 compound treatment 10560.0 -58000.0 -1.8 13640.0 -86300.0 -2.24 -2.8575 -0.994 3559152 ACon1_001370 OC[C@H]1O[C@@H](Oc2ccccc2COC(=O)C3(O)C=CCCC3=O)[C@H](OC(=O)c4ccccc4)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E09 mock treatment 52640.0 -15900.0 -0.49 85120.0 -14900.0 -0.39 -0.6223 -0.9925 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E10 mock treatment 48880.0 -19700.0 -0.61 81400.0 -18600.0 -0.48 -0.773 -0.9932 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E11 compound treatment 46880.0 -21700.0 -0.67 73360.0 -26600.0 -0.69 -0.9645 -0.9999 3554750 ACon1_001371 COC1=CC(=O)O[C@@H](CCc2ccc3OCOc3c2)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E12 compound treatment 27160.0 -41400.0 -1.28 36880.0 -63100.0 -1.64 -2.0668 -0.9927 3558916 ACon1_001372 CC1OC(OC2C(O)C(O)C(CO)OC2OC3C(O)C(O)C(OC3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)C[C@@H](O)[C@]8(C)CC[C@]76C)C4(C)C)C(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E13 compound treatment 53840.0 -14700.0 -0.46 62600.0 -37400.0 -0.97 -1.0097 -0.9409 3555404 ACon1_001373 CON1c2ccccc2[C@@]3(C=C(O)C(=O)N4/C(=C/c5c[nH]cn5)/C(=O)N[C@]143)C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E14 compound treatment 39720.0 -28900.0 -0.89 76240.0 -23700.0 -0.62 -1.0685 -0.9835 3558010 ACon1_001374 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2OC4OC(CO)C(O)C(O)C4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E15 compound treatment 50440.0 -18100.0 -0.56 90160.0 -9810.0 -0.25 -0.5779 -0.936 3554188 ACon1_001375 CCC(O)CC1CCC(O1)C(C)C(=O)OC(CC)CC2CCC(O2)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E16 compound treatment 22720.0 -45900.0 -1.42 28120.0 -71900.0 -1.87 -2.325 -0.9909 3557363 ACon1_001376 CC1=CC2OC3[C@H](O)C[C@@](C)([C@@]43CO4)[C@@]2(CO)[C@H](O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E17 mock treatment 59560.0 -9030.0 -0.28 87480.0 -12500.0 -0.32 -0.4273 -0.9973 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E18 mock treatment 62280.0 -6310.0 -0.2 97440.0 -2530.0 -0.07 -0.1847 -0.8958 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E19 compound treatment 56160.0 -12400.0 -0.39 89440.0 -10500.0 -0.27 -0.4658 -0.986 1001646 ACon1_001377 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@@H]3OC(=O)C)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](OC(=O)C)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E20 compound treatment 9600.0 -59000.0 -1.83 12480.0 -87500.0 -2.27 -2.8998 -0.9941 3557369 ACon1_001378 CC1(C[C@@H](O)[C@H]2C3[C@H]1O)C2(C)CCC[C@]3(C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E21 compound treatment 32440.0 -36100.0 -1.12 49600.0 -50400.0 -1.31 -1.7174 -0.997 3553566 ACon1_001379 CC(C)c1cc2CCC3C(C)(COC(=O)C)C[C@H](O)C[C@]3(C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E22 compound treatment 64280.0 -4310.0 -0.13 104680.0 4710.0 0.12 -0.0079 -0.0435 3558597 ACon1_001380 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)C2C1)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E23 compound treatment 68720.0 133.0 0.0 89400.0 -10600.0 -0.27 -0.1913 -0.6965 3553861 ACon1_001381 CC1(C)CCC[C@@]2(C)[C@H]1[C@H](O)C=C3COC(=O)[C@@]32O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 E24 compound treatment 49200.0 -19400.0 -0.6 78440.0 -21500.0 -0.56 -0.8204 -0.9994 3557439 ACon1_001382 OC(=O)C[C@@H](NCCN[C@H](CC(=O)O)C(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F01 mock treatment 74400.0 5810.0 0.18 112600.0 12600.0 0.33 0.3594 0.9601 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F02 mock treatment 81640.0 13100.0 0.4 115800.0 15800.0 0.41 0.5768 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F03 compound treatment 72000.0 3410.0 0.11 82360.0 -17600.0 -0.46 -0.2488 -0.5298 3559574 ACon1_001383 C[C@H]1CC[C@H](CC2=C(C)C(=O)C[C@@H]12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F04 compound treatment 70720.0 2130.0 0.07 102000.0 2030.0 0.05 0.084 0.9937 3614899 ACon1_001384 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)CC3)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F05 compound treatment 6080.0 -62500.0 -1.94 8160.0 -91800.0 -2.39 -3.0563 -0.9947 3614903 ACon1_001385 C/C=C(\C)/C(=O)OC1C(OC(=O)\C=C(\C)/CC(=O)O)C2(CO)C(O)CC3(C)C(=CCC4C5(C)CCC(OC6OC(C(O)C(OC7OC(C)C(O)C(OC8OC(CO)C(O)C(O)C8O)C7O)C6O)C(=O)O)C(C)(C)C5CCC43C)C2CC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F06 compound treatment 102400.0 33800.0 1.05 141000.0 41000.0 1.07 1.4946 1.0 2119735 ACon1_001386 C[N+](C)(C)C(Cc1c[nH]c2ccccc12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F07 compound treatment 67520.0 -1070.0 -0.03 108760.0 8790.0 0.23 0.1381 0.5984 3614907 ACon1_001387 CCCCCCCC(O)/C=C\C(O)CCC(O)CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F08 compound treatment 87680.0 19100.0 0.59 135840.0 35900.0 0.93 1.0773 0.9759 3614911 ACon1_001388 COc1cc(ccc1O)C2OCC3(OC4OC(CO)C(O)C(O)C4O)C(OCC23)c5ccc(O)c(OC)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F09 mock treatment 81840.0 13300.0 0.41 123160.0 23200.0 0.6 0.7164 0.9825 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F10 mock treatment 80200.0 11600.0 0.36 141320.0 41300.0 1.07 1.0141 0.8951 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F11 compound treatment 74520.0 5930.0 0.18 122800.0 22800.0 0.59 0.5494 0.8847 3614913 ACon1_001389 CC1CC(=O)C2=C(O1)OC3(C)CCC4(O)C(C)(C)CCC(=O)C4(C)C3C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F12 compound treatment 86400.0 17800.0 0.55 131800.0 31800.0 0.83 0.975 0.9807 3614916 ACon1_001390 COC(=O)C[C@H]1/C(=C/C)/[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)OC=C1C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F13 compound treatment 66360.0 -2230.0 -0.07 119040.0 19100.0 0.5 0.3015 0.6028 3614920 ACon1_001391 CC1(C)CCC[C@@]2(C)[C@H]1[C@H](O)C=C(CO)[C@]2(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F14 compound treatment 61840.0 -6750.0 -0.21 103160.0 3190.0 0.08 -0.0893 -0.3969 3614922 ACon1_001392 OC/C=C\1/CN2CCC3(C2CC1C4=CCC(=O)N5C43)c6ccccc56 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F15 compound treatment 76440.0 7850.0 0.24 119240.0 19300.0 0.5 0.526 0.9451 3614924 ACon1_001393 CC(C)CCCCC(=O)OC1OC(CO)C(O)C2OCC(COC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F16 compound treatment 60280.0 -8310.0 -0.26 79440.0 -20500.0 -0.53 -0.5592 -0.9441 1244529 ACon1_001394 CN1CCc2cc3OCOc3c4-c5ccccc5CC1c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F17 mock treatment 72080.0 3490.0 0.11 129240.0 29300.0 0.76 0.6142 0.7997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F18 mock treatment 76640.0 8050.0 0.25 122000.0 22000.0 0.57 0.5811 0.9308 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F19 compound treatment 61440.0 -7150.0 -0.22 77480.0 -22500.0 -0.58 -0.5698 -0.9118 3614927 ACon1_001395 COc1cc-2c(C[C@H]3COC(=O)[C@@H]3Cc4c(OC)c(OC)c(OC)cc42)c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F20 compound treatment 90240.0 21700.0 0.67 124680.0 24700.0 0.64 0.9283 0.9998 3614931 ACon1_001396 CC(=O)N1CCC(CCC(=O)c2ccnc3ccccc23)C(C1)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F21 compound treatment 53280.0 -15300.0 -0.47 84720.0 -15300.0 -0.4 -0.6156 -0.996 3614932 ACon1_001397 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC3=C[C@@H]4C(=CC[C@H]5[C@]6(C)C[C@@H](O)[C@H]([C@@](C)(OC(=O)C)C(=O)/C=C/C(C)(C)O)[C@@]6(C)CC(=O)[C@]54C)C(C)(C)C3=O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F22 compound treatment 76440.0 7850.0 0.24 104760.0 4790.0 0.12 0.26 0.9515 3614935 ACon1_001398 CCN1C[C@]2(COC)CC[C@H](O)[C@]3(C4C[C@H]5[C@@H](OC(=O)C)C4[C@@](C[C@@H]5OC)(OC(=O)C)C6[C@H](OC)C32)[C@@H]61 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F23 compound treatment 61840.0 -6750.0 -0.21 64640.0 -35300.0 -0.92 -0.797 -0.8465 3554229 ACon1_001399 CCCc1c(C(=O)O)c(O)cc2C(=O)c3cccc(O)c3C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 F24 compound treatment 49680.0 -18900.0 -0.59 72320.0 -27700.0 -0.72 -0.9223 -0.9949 3614940 ACon1_001400 CN1CCc2cc3OCOc3cc2C4OC(O)c5c6OCOc6ccc5C41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G01 compound treatment 40040.0 -28500.0 -0.88 58200.0 -41800.0 -1.09 -1.3929 -0.9948 3554156 ACon1_001401 CCC(C)C1NC(=O)C(CCC(=O)O)N(C)C(=O)C(C(C)C)N(C)C(=O)CNC(=O)C2CCCN2C(=O)C(Cc3ccccc3)NC(=O)C(OC(=O)C(CCC(=O)O)N(C)C(=O)C(NC(=O)C4CCCCN4C1=O)C(C)C)C(C)CC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G02 compound treatment 53480.0 -15100.0 -0.47 67200.0 -32800.0 -0.85 -0.9331 -0.9603 3558958 ACon1_001402 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2OC(=O)/C=C/c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G03 mock treatment 56040.0 -12500.0 -0.39 74960.0 -25000.0 -0.65 -0.7344 -0.9698 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G04 mock treatment 61280.0 -7310.0 -0.23 89040.0 -10900.0 -0.28 -0.361 -0.9937 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G05 compound treatment 68600.0 12.5 0.0 93760.0 -6210.0 -0.16 -0.1139 -0.7054 3557320 ACon1_001403 CN/1C(=O)c2ccccc2NC(=O)\C1=C/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G06 compound treatment 53000.0 -15600.0 -0.48 76040.0 -23900.0 -0.62 -0.7812 -0.9922 3559121 ACon1_001404 O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(OC(=O)c4cc(O)c(O)c(O)c4)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G07 compound treatment 52240.0 -16300.0 -0.51 72040.0 -27900.0 -0.73 -0.8713 -0.9845 3559035 ACon1_001405 OC[C@@]12O[C@H]2[C@@H](O)[C@@H]3C=CO[C@@H](O[C@@H]4O[C@H](COC(=O)/C=C/c5ccc(O)cc5)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G08 compound treatment 12040.0 -56500.0 -1.75 18640.0 -81300.0 -2.11 -2.7332 -0.9957 3559216 ACon1_001406 CC(=CCC/C(=C/Cc1cc(cc(CC=C(C)C)c1O)C(=O)O)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G09 compound treatment 57360.0 -11200.0 -0.35 73600.0 -26400.0 -0.69 -0.7305 -0.9506 3559155 ACon1_001407 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)C[C@@H](O)[C@@]31O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G10 compound treatment 6800.0 -61800.0 -1.91 9240.0 -90700.0 -2.36 -3.0207 -0.9947 1089114 ACon1_001408 COc1cc(O)c(Cc2ccccc2O)c(O)c1C(=O)CCc3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G11 compound treatment 71960.0 3370.0 0.1 93720.0 -6250.0 -0.16 -0.041 -0.2122 3553711 ACon1_001409 CC(CCCc1ccoc1)C2CC=C(CCC=C(C)C)C(=O)O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G12 compound treatment 70560.0 1970.0 0.06 94600.0 -5370.0 -0.14 -0.0555 -0.3641 3557253 ACon1_001410 CC(=CCC/C(=C/CC[C@]1(C)Oc2c3CNC(=O)c3cc(O)c2C[C@@H]1O)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G13 compound treatment 61440.0 -7150.0 -0.22 86320.0 -13700.0 -0.35 -0.4074 -0.9743 3554972 ACon1_001411 COc1cc(O)c(CCO)c2O[C@H](C)CC(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G14 compound treatment 52000.0 -16600.0 -0.51 87520.0 -12500.0 -0.32 -0.5922 -0.9751 3557300 ACon1_001412 CC(O)CC1CCC(O1)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G15 compound treatment 41560.0 -27000.0 -0.84 70200.0 -29800.0 -0.77 -1.1391 -0.9992 3553811 ACon1_001413 CC[C@H](O)C[C@@H]1CC[C@@H](O1)[C@@H](C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G16 compound treatment 60560.0 -8030.0 -0.25 82160.0 -17800.0 -0.46 -0.5031 -0.9576 3558027 ACon1_001414 C[C@@H]1O[C@@H](O[C@@H]2C=C(CO)[C@@H]3[C@H]2C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](OC(=O)/C=C/c5ccc(O)cc5)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G17 compound treatment 36400.0 -32200.0 -1.0 55240.0 -44700.0 -1.16 -1.5271 -0.9971 3553505 ACon1_001415 CC(C)[C@H]1OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C1=O)C(C)C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G18 compound treatment 69800.0 1210.0 0.04 96600.0 -3370.0 -0.09 -0.0354 -0.3712 3557922 ACon1_001416 CC(=O)OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G19 mock treatment 68560.0 -27.5 0.0 109720.0 9750.0 0.25 0.1785 0.7047 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G20 mock treatment 71440.0 2850.0 0.09 106680.0 6710.0 0.17 0.1857 0.9505 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G21 compound treatment 100400.0 31800.0 0.99 137160.0 37200.0 0.97 1.3802 1.0 3552815 ACon1_001417 C[C@]1(C[C@]2(O)O[C@@H]3O1)[C@]4(C[C@@H]2[C@@]34COC(=O)c5ccccc5)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G22 compound treatment 66120.0 -2470.0 -0.08 84000.0 -16000.0 -0.41 -0.3475 -0.8235 1109010 ACon1_001418 COc1cc(cc2OCOc21)C3OCC4C(OCC34)c5cc(OC)c(OC)c(OC)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G23 compound treatment 68920.0 333.0 0.01 89360.0 -10600.0 -0.28 -0.1877 -0.6802 3557629 ACon1_001419 COc1cc(ccc1O)c2oc3cc(O)cc(O)c3c(=O)c2OC4OC(CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C(O)C(O)C4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 G24 compound treatment 53560.0 -15000.0 -0.47 78920.0 -21100.0 -0.55 -0.716 -0.9968 3553937 ACon1_001420 CC1=CC(=O)C2C(C)(C)C(O)CCC2(C)C1(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H01 compound treatment 59360.0 -9230.0 -0.29 93680.0 -6290.0 -0.16 -0.3178 -0.9648 3555028 ACon1_001421 COc1cc2C(O)CCC(=O)c2c(O)c1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H02 compound treatment 4600.0 -64000.0 -1.98 5480.0 -94500.0 -2.46 -3.138 -0.9944 3614951 ACon1_001422 Cc1cc(O)c2C(=O)C3=C(C(O)C(O)C(O)C3O)C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H03 mock treatment 79400.0 10800.0 0.34 119520.0 19500.0 0.51 0.596 0.9796 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H04 mock treatment 89440.0 20900.0 0.65 135440.0 35500.0 0.92 1.1085 0.9849 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H05 compound treatment 7760.0 -60800.0 -1.88 8960.0 -91000.0 -2.36 -3.0048 -0.9937 1074963 ACon1_001423 Cc1cc(O)c2C(=O)C3=C(O)C4C(O)C5C6C(O)C(C(=C7C(=O)c8c(O)cc(C)cc8C(=O)C647)O)C53C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H06 compound treatment 66440.0 -2150.0 -0.07 102600.0 2630.0 0.07 0.0012 0.0129 3614955 ACon1_001424 CCCCCC(CC(O)CC(=O)OC(CCCCC)CC(CC(=O)O)OC1OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C(O)C1O)OC3OC(CO)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H07 compound treatment 71240.0 2650.0 0.08 104200.0 4230.0 0.11 0.1358 0.9898 3614956 ACon1_001425 C[C@H]1OC(=O)[C@@]2(C(=C)[C@]3(C)C[C@@H]4C(=C)[C@]5(CC[C@]42C)C=CC(=O)OC5(C)C)[C@@]1(O)C3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H08 compound treatment 77520.0 8930.0 0.28 114040.0 14100.0 0.37 0.4542 0.9906 3614960 ACon1_001426 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H09 compound treatment 20560.0 -48000.0 -1.49 27920.0 -72100.0 -1.87 -2.376 -0.9935 3614965 ACon1_001427 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](O)[C@H](O[C@@H]9OC[C@H](O)[C@H](O)[C@H]9O)[C@H]1O[C@@H]%10OC[C@@H](O)[C@H](O[C@@H]%11OC[C@H](O)[C@H](O)[C@H]%11O)[C@H]%10O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H10 compound treatment 76480.0 7890.0 0.24 122920.0 22900.0 0.6 0.5945 0.9225 3614969 ACon1_001428 C[C@H]1OC(=O)CC[C@@H](O)/C=C/[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H11 compound treatment 9640.0 -58900.0 -1.83 12360.0 -87600.0 -2.28 -2.9012 -0.994 3614972 ACon1_001429 COc1cc(ccc1O)C2OC(c3ccc(O)c(OC)c3)C(C)(O)C2C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H12 compound treatment 80720.0 12100.0 0.38 115680.0 15700.0 0.41 0.5544 0.9992 3614974 ACon1_001430 C[C@@H]1CCC2C(C)(C)[C@H](OC(=O)C)[C@@H](O)C[C@]2(C)C31Cc4c(O3)c5CN([C@@H](CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H13 compound treatment 11240.0 -57300.0 -1.78 33000.0 -67000.0 -1.74 -2.4869 -0.9999 3559258 ACon1_001431 CC1OC(OC2C(O)C(CO)OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)OC8OCC(OC9OCC(O)C(O)C9O)C(O)C8O)C3(C)C)C2O)C(O)C(OC%10OCC(O)(CO)C%10O)C1OC%11OCC(O)(CO)C%11O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H14 compound treatment 62600.0 -5990.0 -0.19 99400.0 -572.0 -0.01 -0.1417 -0.7613 3614977 ACon1_001432 COc1cc2N3C4C5C(CC3=O)OCC=C6CN(C)CCC4(C(=O)CC56)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H15 compound treatment 64920.0 -3670.0 -0.11 87040.0 -12900.0 -0.34 -0.3179 -0.8964 3614978 ACon1_001433 CC1CC(=O)C2=C(O1)OC3(C)CCC4C(C)(C)C(O)CC(O)C4(C)C3C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H16 compound treatment 70160.0 1570.0 0.05 110800.0 10800.0 0.28 0.2334 0.8174 3614980 ACon1_001434 OC(C1CC2CC[N+]1([O-])CC2C=C)c3ccnc4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H17 compound treatment 76360.0 7770.0 0.24 105320.0 5350.0 0.14 0.2685 0.9659 3614982 ACon1_001435 CC1OC(OC2C(O)C(OC3OC(C)C(OC(=O)C)C(O)C3O)C(CO)OC2OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](OC9OC(CO)C(OC%10OC(CO)C(OC%11OCC(O)C(O)C%11O)C(O)C%10O)C(O)C9O)[C@@](C)(CO)C8CC[C@@]7(C)[C@]6(C)CC4)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H18 compound treatment 77120.0 8530.0 0.26 107640.0 7670.0 0.2 0.3278 0.9903 3614986 ACon1_001436 C=CC1CN(CCC1CCC(=O)c2ccnc3ccccc23)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H19 mock treatment 85640.0 17100.0 0.53 126880.0 26900.0 0.7 0.868 0.9905 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H20 mock treatment 78520.0 9930.0 0.31 115280.0 15300.0 0.4 0.4989 0.992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H21 compound treatment 18560.0 -50000.0 -1.55 26520.0 -73500.0 -1.91 -2.4456 -0.9947 3614988 ACon1_001437 OC[C@H]1O[C@@H](Oc2c(O)cccc2COC(=O)C3(O)C4C=CC(C3=O)c5ccc(O)c(O)c45)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H22 compound treatment 69040.0 453.0 0.01 89640.0 -10300.0 -0.27 -0.1799 -0.6693 3614991 ACon1_001438 C=Cc1cncc2c(=O)n3CCc4c([nH]c5ccccc45)-c3cc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H23 compound treatment 65680.0 -2910.0 -0.09 85360.0 -14600.0 -0.38 -0.3322 -0.8513 3614994 ACon1_001439 CC1OC(O[C@H]2[C@@H](O)C[C@]3(C)C4CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@@]5(C)[C@]4(C)C[C@@H](O)C3[C@]2(C)CO)C(=O)OC7OC(C)C(OC8OCC(OC9OCC(O)C(OC%10OCC(O)C(O)C%10O)C9O)C(O)C8O)C(O)C7O)C(O)C(OC%11OC(CO)C(O)C(O)C%11O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 H24 compound treatment 38120.0 -30500.0 -0.94 54000.0 -46000.0 -1.19 -1.5122 -0.9932 3614997 ACon1_001440 CN1Cc2cc3OCOc3cc2CCC(=O)c4cc5OCOc5cc4C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I01 compound treatment 35800.0 -32800.0 -1.02 57080.0 -42900.0 -1.11 -1.5064 -0.9989 3552717 ACon1_001441 C[C@@H]1CCC2C(C)(C)[C@H](O)CC[C@]2(C)[C@]31Cc4c(O3)c5CN([C@@H](CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I02 compound treatment 57400.0 -11200.0 -0.35 79960.0 -20000.0 -0.52 -0.6128 -0.9806 3559086 ACon1_001442 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C(O)CC3(C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I03 compound treatment 62280.0 -6310.0 -0.2 67920.0 -32100.0 -0.83 -0.7271 -0.85 3559083 ACon1_001443 OCC1OC(OC2C(O)C(O)C(CO)OC2Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I04 compound treatment 58760.0 -9830.0 -0.3 75080.0 -24900.0 -0.65 -0.6726 -0.9409 3559093 ACon1_001444 COc1cc(ccc1O)[C@@H]2[C@@H](CO)[C@](O)(CO)Cc3cc(OC)c(O)cc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I05 mock treatment 69560.0 973.0 0.03 79120.0 -20900.0 -0.54 -0.3618 -0.6668 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I06 mock treatment 59000.0 -9590.0 -0.3 80560.0 -19400.0 -0.5 -0.5667 -0.9681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I07 compound treatment 5600.0 -63000.0 -1.95 7840.0 -92100.0 -2.39 -3.0727 -0.9949 3558957 ACon1_001445 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I08 compound treatment 40800.0 -27800.0 -0.86 48800.0 -51200.0 -1.33 -1.549 -0.9779 3557372 ACon1_001446 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@]54OO[C@@]23C=C5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I09 compound treatment 5560.0 -63000.0 -1.95 8640.0 -91300.0 -2.37 -3.0589 -0.9953 3615002 ACon1_001447 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O)O[C@@]%101CC[C@@](C)(CO[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)O%10 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I10 compound treatment 52440.0 -16100.0 -0.5 70000.0 -30000.0 -0.78 -0.9044 -0.9771 3558208 ACon1_001448 COc1cc(/C=C/C(=O)O[C@H]2[C@H](O)[C@@H](C)O[C@H](O[C@@H]3C4O[C@]4(CO)C5C3C=CO[C@H]5O[C@H]6O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]6O)[C@H]2OC(=O)C)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I11 compound treatment 53080.0 -15500.0 -0.48 72200.0 -27800.0 -0.72 -0.85 -0.9805 3553143 ACon1_001449 C[C@H]1CC[C@H]2O[C@]23C(=O)c4occ(C)c4[C@@H](OC(=O)C)[C@]13C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I12 compound treatment 10240.0 -58300.0 -1.81 12720.0 -87300.0 -2.27 -2.8814 -0.9937 3557701 ACon1_001450 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I13 compound treatment 53280.0 -15300.0 -0.47 64960.0 -35000.0 -0.91 -0.9786 -0.9539 3552066 ACon1_001451 C/C=C/C=C/C(=C/1\[C@@H]2[C@@H]([C@@H](C(=O)\C=C\C=C\C)[C@](C)(C1=O)C(=O)C2(C)O)[C@]3(C)OC(=O)C(=C3O)C)/O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I14 compound treatment 52520.0 -16100.0 -0.5 81800.0 -18200.0 -0.47 -0.6859 -0.9996 3558037 ACon1_001452 OC[C@H]1O[C@@H](Oc2ccccc2COC(=O)c3c(O)cccc3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I15 compound treatment 56680.0 -11900.0 -0.37 83000.0 -17000.0 -0.44 -0.5727 -0.9961 3555441 ACon1_001453 CSCC1OC(C(O)C1O)n2cnc3c(=O)[nH]cnc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I16 compound treatment 65320.0 -3270.0 -0.1 80040.0 -19900.0 -0.52 -0.4378 -0.8296 3557495 ACon1_001454 CC1OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)C(O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I17 compound treatment 7280.0 -61300.0 -1.9 15840.0 -84100.0 -2.19 -2.8889 -0.9976 3555348 ACon1_001455 COc1nc(C/C=C(\C)/C\C=C\C(=C\[C@@H](C)[C@@H](O)\C(=C\C)\C)\C)c(C)c(O)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I18 compound treatment 69320.0 733.0 0.02 107920.0 7950.0 0.21 0.1621 0.7801 3559191 ACon1_001456 CC(C)C[C@@](O)([C@H](O)C(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)C(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I19 compound treatment 80840.0 12300.0 0.38 108000.0 8030.0 0.21 0.4159 0.9602 3555032 ACon1_001457 COc1cc2nc3occc3c(OC)c2cc1OCC(OC(=O)C)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I20 compound treatment 80240.0 11700.0 0.36 95920.0 -4050.0 -0.11 0.1809 0.4809 3559208 ACon1_001458 COC(=O)[C@]1(C)CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3(C[C@H]4C(=O)O)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I21 mock treatment 81120.0 12500.0 0.39 104000.0 4030.0 0.1 0.3486 0.8668 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I22 mock treatment 77480.0 8890.0 0.28 109440.0 9470.0 0.25 0.3688 0.9984 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I23 compound treatment 69320.0 733.0 0.02 72920.0 -27100.0 -0.7 -0.481 -0.6839 3552080 ACon1_001459 C/C=C/C=C/C(=O)c1cc(C)c(O)c(C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 I24 compound treatment 62280.0 -6310.0 -0.2 69480.0 -30500.0 -0.79 -0.6984 -0.8559 3557310 ACon1_001460 CC(O)Cc1cc2c(C)cc(O)cc2c(=O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J01 compound treatment 29360.0 -39200.0 -1.22 42720.0 -57300.0 -1.49 -1.9113 -0.995 3557337 ACon1_001461 C[C@H](O)CC1=C[C@H](O)[C@@H](C)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J02 compound treatment 5560.0 -63000.0 -1.95 7400.0 -92600.0 -2.41 -3.0817 -0.9947 3553966 ACon1_001462 CC1CC(=O)c2c(C1)ccc3C(O)c4c(O)cccc4C(=O)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J03 compound treatment 75240.0 6650.0 0.21 113160.0 13200.0 0.34 0.388 0.9704 3559779 ACon1_001463 C[C@H]1[C@@H](O)[C@H](O)C[C@]2(C)CC[C@H](C=C12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J04 compound treatment 93480.0 24900.0 0.77 129120.0 29100.0 0.76 1.0809 1.0 3615013 ACon1_001464 CC(=O)Cc1cc(O)cc2oc(C)cc(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J05 mock treatment 86200.0 17600.0 0.55 108480.0 8510.0 0.22 0.5422 0.9209 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J06 mock treatment 83320.0 14700.0 0.46 128320.0 28300.0 0.74 0.8436 0.9735 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J07 compound treatment 73760.0 5170.0 0.16 98640.0 -1330.0 -0.03 0.0889 0.5419 3615015 ACon1_001465 COC(=O)Cc1c(CCC(=O)O)oc2cc(C)cc(O)c2c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J08 compound treatment 81480.0 12900.0 0.4 89360.0 -10600.0 -0.28 0.0875 0.1803 1057044 ACon1_001466 COc1ccc(cc1O)c2oc3cc(O)cc(O)c3c(=O)c2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J09 compound treatment 55480.0 -13100.0 -0.41 66240.0 -33700.0 -0.88 -0.9069 -0.9389 3615018 ACon1_001467 O[C@@H]1CO[C@@H](OC(CCCCc2ccc(O)cc2)CCc3ccc(O)cc3)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J10 compound treatment 89120.0 20500.0 0.64 111360.0 11400.0 0.3 0.6591 0.9394 3615022 ACon1_001468 COC(=O)c1c(C)cc2CC3(Oc2c(C)c1=O)C(C)CCC4C3(C)C=CC(=O)OC4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J11 compound treatment 38280.0 -30300.0 -0.94 72160.0 -27800.0 -0.72 -1.175 -0.9916 3615023 ACon1_001469 CC1CCC2C(C)(C)CCCC2(C)C1(O)/C=C/C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J12 compound treatment 79880.0 11300.0 0.35 97840.0 -2130.0 -0.06 0.2082 0.5878 2060335 ACon1_001470 Oc1ccc2C3Oc4cc5OCOc5cc4C3COc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J13 compound treatment 70480.0 1890.0 0.06 111280.0 11300.0 0.29 0.2492 0.8318 3615027 ACon1_001471 C[C@H]1[C@H]2OC3=C(C(=O)OC3(C)O)C(=O)[C@]1(C)[C@H]4CCCC[C@]4(O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J14 compound treatment 25440.0 -43100.0 -1.34 52560.0 -47400.0 -1.23 -1.8164 -0.9992 3615031 ACon1_001472 C1Oc2cc3CCNC4Cc5ccccc5-c(c2O1)c43 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J15 compound treatment 53480.0 -15100.0 -0.47 79880.0 -20100.0 -0.52 -0.7001 -0.9985 3557473 ACon1_001473 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(CO)COP(=O)(O)OCC[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J16 compound treatment 79760.0 11200.0 0.35 112440.0 12500.0 0.32 0.4739 0.9995 1093674 ACon1_001474 COc1ccc(Cc2nccc3cc(O)c(OC)cc23)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J17 compound treatment 7960.0 -60600.0 -1.88 31080.0 -68900.0 -1.79 -2.594 -0.9997 3615035 ACon1_001475 CCCCCCCCCC(O)C(C)C(O)C(CO)/C=C(\C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J18 compound treatment 61920.0 -6670.0 -0.21 79080.0 -20900.0 -0.54 -0.5299 -0.9124 1014127 ACon1_001476 COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J19 compound treatment 60720.0 -7870.0 -0.24 82000.0 -18000.0 -0.47 -0.5026 -0.9541 3615039 ACon1_001477 COC(=O)c1cc(O)c(O)c(O)c1c2c(O)c(O)c3oc(=O)c4cc(O)c(O)c5oc(=O)c2c3c45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J20 compound treatment 64520.0 -4070.0 -0.13 90960.0 -9010.0 -0.23 -0.2547 -0.9578 3615041 ACon1_001478 CCC1C2C34CC[N+]2([O-])CCC1C(=C4Nc5c3cccc5OC)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J21 mock treatment 84560.0 16000.0 0.49 94080.0 -5890.0 -0.15 0.2417 0.4666 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J22 mock treatment 76720.0 8130.0 0.25 95280.0 -4690.0 -0.12 0.092 0.3286 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J23 compound treatment 30040.0 -38500.0 -1.19 26640.0 -73300.0 -1.91 -2.1919 -0.9747 3615043 ACon1_001479 CCCC(O)c1c(O)cccc1C/2(O)CC(=O)C\C2=C/C(O)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 J24 compound treatment 33720.0 -34900.0 -1.08 42440.0 -57500.0 -1.49 -1.8209 -0.9873 3615046 ACon1_001480 COC1OC2C(N(C)CCc3cc4OCOc4cc23)c5ccc6OCOc6c15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K01 compound treatment 26400.0 -42200.0 -1.31 31640.0 -68300.0 -1.78 -2.1797 -0.9887 3559758 ACon1_001481 CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K02 compound treatment 63120.0 -5470.0 -0.17 67280.0 -32700.0 -0.85 -0.7204 -0.8317 3559087 ACon1_001482 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)OC(=O)C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K03 compound treatment 54440.0 -14100.0 -0.44 71400.0 -28600.0 -0.74 -0.8349 -0.9684 3559128 ACon1_001483 C[N+](C)(C)C(Cc1ccccc1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K04 compound treatment 56080.0 -12500.0 -0.39 70000.0 -30000.0 -0.78 -0.8247 -0.9481 3558370 ACon1_001484 CC(=O)OCC1=C[C@H](O)[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K05 compound treatment 49520.0 -19100.0 -0.59 68120.0 -31900.0 -0.83 -1.003 -0.9863 3559003 ACon1_001485 COc1ccc(CC2C(Cc3ccc4OCOc4c3)COC2=O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K06 compound treatment 6040.0 -62500.0 -1.94 7560.0 -92400.0 -2.4 -3.0682 -0.9944 3553192 ACon1_001486 CC(=CCc1c(O)cc2oc3c(CC=C(C)C)c(O)c(O)c(CC=C(C)C)c3c(=O)c2c1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K07 mock treatment 63400.0 -5190.0 -0.16 79800.0 -20200.0 -0.52 -0.4843 -0.8833 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K08 mock treatment 55520.0 -13100.0 -0.4 73480.0 -26500.0 -0.69 -0.773 -0.968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K09 compound treatment 7320.0 -61300.0 -1.9 8720.0 -91300.0 -2.37 -3.0189 -0.9939 3554961 ACon1_001487 COc1cc(O)c(C(=O)c2c(C)cc(O)cc2OC)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K10 compound treatment 69200.0 613.0 0.02 89520.0 -10500.0 -0.27 -0.1786 -0.6561 3558843 ACon1_001488 COc1cc2c(ccc3cc(OC)c(OC)c(O)c32)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K11 compound treatment 55560.0 -13000.0 -0.4 80960.0 -19000.0 -0.49 -0.6347 -0.995 1254 ACon1_001489 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K12 compound treatment 15880.0 -52700.0 -1.63 31400.0 -68600.0 -1.78 -2.4146 -0.9991 3557313 ACon1_001490 C[C@H]1CC[C@@H]2[C@H]([C@@H](C)C=C[C@H]2C1)C(=O)c3c(O)c(c[nH]c3=O)[C@]4(O)CC[C@@H](O)[C@H]5O[C@H]54 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K13 compound treatment 23520.0 -45100.0 -1.4 51920.0 -48100.0 -1.25 -1.8702 -0.9984 3555009 ACon1_001491 COc1cc(OC)c2c(O)c3CO[C@@H](C)[C@@H](O)c3c(c4c5[C@H](O)[C@H](C)OCc5c(O)c6c(OC)cc(OC)cc46)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K14 compound treatment 58560.0 -10000.0 -0.31 76680.0 -23300.0 -0.61 -0.6476 -0.952 3559158 ACon1_001492 Cc1ccc2C(=O)c3cc(O[C@@H]4O[C@H](CO[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)ccc3C(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K15 mock treatment 62600.0 -5990.0 -0.19 88040.0 -11900.0 -0.31 -0.3504 -0.9699 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K16 mock treatment 65280.0 -3310.0 -0.1 79640.0 -20300.0 -0.53 -0.446 -0.8288 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K17 compound treatment 44680.0 -23900.0 -0.74 66080.0 -33900.0 -0.88 -1.1465 -0.9963 3552826 ACon1_001493 C[C@]1(CO)CCC[C@@]2(C)C1[C@H](O)CC3=C2COC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K18 compound treatment 7680.0 -60900.0 -1.89 9360.0 -90600.0 -2.35 -2.9992 -0.994 3559193 ACon1_001494 CC(C)C[C@](CC(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)OCc4ccc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K19 compound treatment 87560.0 19000.0 0.59 114760.0 14800.0 0.38 0.6874 0.9788 3557988 ACon1_001495 OC[C@H]1O[C@@H](Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K20 compound treatment 72800.0 4210.0 0.13 102240.0 2270.0 0.06 0.134 0.9354 3557832 ACon1_001496 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]4OC[C@](O)(CO)[C@H]4O)[C@H]2OC(=O)/C=C/c5ccc(O)c(O)c5)[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K21 compound treatment 86080.0 17500.0 0.54 98560.0 -1410.0 -0.04 0.3573 0.6577 3557515 ACon1_001497 OC[C@@]1(O)CO[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K22 compound treatment 22720.0 -45900.0 -1.42 28920.0 -71100.0 -1.85 -2.3103 -0.9916 3559214 ACon1_001498 CC/C=C\C=C\1/C(CCCCCCCC(=O)O)C=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K23 mock treatment 69240.0 653.0 0.02 94560.0 -5410.0 -0.14 -0.0851 -0.5993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 K24 mock treatment 56840.0 -11700.0 -0.36 78880.0 -21100.0 -0.55 -0.6449 -0.9802 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L01 compound treatment 60160.0 -8430.0 -0.26 81800.0 -18200.0 -0.47 -0.5185 -0.961 3552939 ACon1_001499 C[C@H](O)c1nc2ccccc2c(=O)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L02 compound treatment 70160.0 1570.0 0.05 89200.0 -10800.0 -0.28 -0.1635 -0.5754 3615055 ACon1_001500 CC/C=C/c1ccc(C)cc1CCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L03 compound treatment 85560.0 17000.0 0.53 91920.0 -8050.0 -0.21 0.2239 0.3956 3559801 ACon1_001501 C[C@@H]1[C@H]2[C@H](OC1=O)[C@H]3C(=CC(=O)C3=C(C)C[C@@H]2O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L04 compound treatment 8160.0 -60400.0 -1.87 10160.0 -89800.0 -2.33 -2.974 -0.994 3615060 ACon1_001502 COc1cc(O)c(CC=C(C)C)c(/C=C/c2ccc(OC)c(O)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L05 compound treatment 72520.0 3930.0 0.12 78200.0 -21800.0 -0.57 -0.3139 -0.5424 3615064 ACon1_001503 COc1cc(CCC(=O)N2CCC=CC2=O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L06 compound treatment 76880.0 8290.0 0.26 112240.0 12300.0 0.32 0.4071 0.9943 3615066 ACon1_001504 CCCC1=C(/C=C/C(=O)O)C(=O)C(O1)C(C)(C)C2OC(=C(/C=C/C(=O)O)C2=O)CCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L07 mock treatment 83640.0 15100.0 0.47 104240.0 4270.0 0.11 0.4082 0.8515 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L08 mock treatment 75760.0 7170.0 0.22 104080.0 4110.0 0.11 0.2326 0.9435 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L09 compound treatment 5040.0 -63500.0 -1.97 6720.0 -93300.0 -2.42 -3.1056 -0.9947 2113350 ACon1_001505 COc1cc(CC(C)C(C)Cc2ccc(O)c(OC)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L10 compound treatment 68960.0 373.0 0.01 105560.0 5590.0 0.15 0.1108 0.7609 3615071 ACon1_001506 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OC[C@@H]3[C@H](C)[C@H](C[C@H]3C(CO)CO)OC(=O)CC4\C(=C\C)\C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)OC=C4C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L11 compound treatment 5040.0 -63500.0 -1.97 7280.0 -92700.0 -2.41 -3.0953 -0.995 3615072 ACon1_001507 CC1CC(=O)[C@]2(C)CC[C@]3(C)C(=C(O)C(O)C4[C@@]5(C)CC[C@H](O)C(C)(C5CC[C@]43C)C(=O)O)C2C1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L12 compound treatment 70120.0 1530.0 0.05 109840.0 9870.0 0.26 0.2149 0.824 3557524 ACon1_001508 OC1COC(OCC2OC(OCc3ccccc3)C(O)C(O)C2O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L13 compound treatment 5560.0 -63000.0 -1.95 8640.0 -91300.0 -2.37 -3.0589 -0.9953 3615077 ACon1_001509 CC1CCC2C(C)(C)CCCC2(C)C1(O)C/C=C(\CCOC(=O)C)/COC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L14 compound treatment 75320.0 6730.0 0.21 95920.0 -4050.0 -0.11 0.0731 0.3127 3615080 ACon1_001510 CCC(O)CC1CCCC(CC(O)c2ccccc2)N1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L15 mock treatment 79480.0 10900.0 0.34 92080.0 -7890.0 -0.21 0.0936 0.2371 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L16 mock treatment 75560.0 6970.0 0.22 102200.0 2230.0 0.06 0.1937 0.866 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L17 compound treatment 24400.0 -44200.0 -1.37 33360.0 -66600.0 -1.73 -2.192 -0.9933 3615082 ACon1_001511 C[C@H]1CC[C@@H]2N(C1)C[C@H]3[C@@H]4C[C@]5(O[C@@]6(O)[C@H]7C[C@@H](O)[C@H]5[C@]4(O)[C@@H](O)[C@H](O)[C@@H]3[C@]2(C)O)[C@@]7(C)CC[C@@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L18 compound treatment 73600.0 5010.0 0.16 87680.0 -12300.0 -0.32 -0.116 -0.3267 3615084 ACon1_001512 CCN1C[C@]2(C)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@@](C[C@@H]5OC)(OC)C6[C@@H](OC(=O)C)C32)[C@@H]61 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L19 compound treatment 50720.0 -17900.0 -0.55 48160.0 -51800.0 -1.35 -1.3434 -0.9229 3615086 ACon1_001513 CC(C)C1NC(=O)C(C)NC(=O)CCCNC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)NC(=O)C(NC(=O)C(NC1=O)C(C)c4ccccc4)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L20 compound treatment 80160.0 11600.0 0.36 86840.0 -13100.0 -0.34 0.0123 0.0248 1050697 ACon1_001514 CC(C)C(O)(C(C)O)C(=O)OCC1=CCN2CCC(O)C21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L21 compound treatment 61040.0 -7550.0 -0.23 62120.0 -37900.0 -0.98 -0.8608 -0.8515 3615088 ACon1_001515 C[C@@H]1O[C@@H](O[C@H]2[C@H](C)O[C@@H](OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H]8O)[C@@](C)(CO)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](O[C@@H]%11O[C@@H](CO)[C@H](O)[C@H]%11O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L22 compound treatment 69480.0 893.0 0.03 72920.0 -27100.0 -0.7 -0.4775 -0.6788 3615092 ACon1_001516 COc1cc2CCN(C)C3c4c(CC3(O)c2cc1O)ccc5OCOc54 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L23 mock treatment 63320.0 -5270.0 -0.16 96440.0 -3530.0 -0.09 -0.1803 -0.9629 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 L24 mock treatment 42800.0 -25800.0 -0.8 79800.0 -20200.0 -0.52 -0.9356 -0.9791 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M01 compound treatment 43920.0 -24700.0 -0.76 59120.0 -40900.0 -1.06 -1.291 -0.987 3553702 ACon1_001517 CC(CCC1(C)C(C)CCC2(CO)C1CCC=C2CO)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M02 compound treatment 50240.0 -18300.0 -0.57 52760.0 -47200.0 -1.23 -1.2694 -0.9389 3559098 ACon1_001518 COc1c(O)cc(cc1O)[C@@H]2Oc3cc(O)cc(O)c3C[C@@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M03 compound treatment 53680.0 -14900.0 -0.46 68960.0 -31000.0 -0.81 -0.8964 -0.9651 3559053 ACon1_001519 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]1OC(=O)/C=C/c6ccccc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M04 compound treatment 61480.0 -7110.0 -0.22 73080.0 -26900.0 -0.7 -0.6498 -0.887 3559037 ACon1_001520 COc1cc(ccc1O)C(=O)O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M05 compound treatment 58720.0 -9870.0 -0.31 69080.0 -30900.0 -0.8 -0.7838 -0.9125 3554112 ACon1_001521 CCC(C)/C=C/C1=CC2=C(Cl)C(=O)C3(C)OC(=O)C(C3C2=CO1)C(=O)C(C)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M06 compound treatment 65960.0 -2630.0 -0.08 81720.0 -18300.0 -0.47 -0.3929 -0.8165 3559185 ACon1_001522 C[C@]12C[C@H](OC(=O)C2CC[C@]3(C)[C@H]1[C@@H]4OC(=O)[C@@]3(O)C=C4)c5ccoc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M07 compound treatment 54080.0 -14500.0 -0.45 70520.0 -29500.0 -0.77 -0.859 -0.9678 3559057 ACon1_001523 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3[C@@H]4O[C@]4(CO)[C@@H]5[C@H]3C=CO[C@H]5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@@H]2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M08 compound treatment 48080.0 -20500.0 -0.64 55200.0 -44800.0 -1.16 -1.2719 -0.9595 3557382 ACon1_001524 CC(=O)N(O)CCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M09 mock treatment 53160.0 -15400.0 -0.48 75240.0 -24700.0 -0.64 -0.7924 -0.9894 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M10 mock treatment 59280.0 -9310.0 -0.29 76640.0 -23300.0 -0.61 -0.6326 -0.9423 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M11 compound treatment 9960.0 -58600.0 -1.82 12440.0 -87500.0 -2.27 -2.8927 -0.9938 3553353 ACon1_001525 CC(=O)OC/1C\C=C(/C)\CC(OC(=O)/C(=C\CO)/C)C2C(OC(=O)C2=C)\C=C1/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M12 compound treatment 59480.0 -9110.0 -0.28 81800.0 -18200.0 -0.47 -0.5334 -0.9697 3558922 ACon1_001526 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@]1(C)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M13 mock treatment 51440.0 -17100.0 -0.53 80680.0 -19300.0 -0.5 -0.7301 -0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M14 mock treatment 52040.0 -16500.0 -0.51 67320.0 -32700.0 -0.85 -0.9624 -0.9709 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M15 compound treatment 36040.0 -32500.0 -1.01 50480.0 -49500.0 -1.29 -1.6224 -0.9928 3554846 ACon1_001527 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(OC)c2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M16 compound treatment 64640.0 -3950.0 -0.12 71280.0 -28700.0 -0.75 -0.6136 -0.8123 3558380 ACon1_001528 COc1cc(CCOC2OC(CO)C(OC(=O)/C=C/c3ccc(O)c(OC)c3)C(OC4OC(C)C(O)C(O)C4O)C2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M17 compound treatment 67880.0 -708.0 -0.02 84400.0 -15600.0 -0.4 -0.3016 -0.7443 3554709 ACon1_001529 COC(=O)c1cc(O)cc(OC)c1Oc2cc(C)cc(O)c2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M18 compound treatment 6000.0 -62600.0 -1.94 7440.0 -92500.0 -2.4 -3.0713 -0.9943 3557627 ACon1_001530 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O[C@@H]6OC[C@](O)(CO)[C@H]6O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M19 compound treatment 3760.0 -64800.0 -2.01 4400.0 -95600.0 -2.48 -3.1762 -0.9945 3552018 ACon1_001531 C/C=C(/C)\C(=O)O[C@H]1C=C(C)C[C@H](OC(=O)c2ccc(O)cc2)C3[C@@](O)(CC[C@@]31C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M20 compound treatment 8560.0 -60000.0 -1.86 12040.0 -87900.0 -2.28 -2.9307 -0.9948 3558024 ACon1_001532 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccc(O)cc6)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M21 compound treatment 73120.0 4530.0 0.14 96000.0 -3970.0 -0.1 0.0263 0.1511 3553253 ACon1_001533 CC(=O)Cc1cc(=O)c2c(C)cc(O)c(C3OC(CO)C(O)C(O)C3O)c2o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M22 compound treatment 63520.0 -5070.0 -0.16 78880.0 -21100.0 -0.55 -0.4985 -0.8745 3559206 ACon1_001534 CC1(C)C(O)CCC2(C)C3CCC4CC3(CC4(O)CO)CCC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M23 compound treatment 60320.0 -8270.0 -0.26 67240.0 -32700.0 -0.85 -0.7825 -0.881 3559039 ACon1_001535 COc1cc(/C=C/C(=O)O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 M24 compound treatment 44840.0 -23700.0 -0.74 65520.0 -34500.0 -0.9 -1.1533 -0.9953 3553939 ACon1_001536 CC1=CC(=O)C2C(C)(C)CC(O)CC2(C)C1(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N01 compound treatment 58720.0 -9870.0 -0.31 71960.0 -28000.0 -0.73 -0.7308 -0.9258 1037131 ACon1_001537 Cc1cc(C)c(O)c(c1)C(=O)CC2CC(=O)NC(=O)C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N02 compound treatment 68120.0 -468.0 -0.01 81200.0 -18800.0 -0.49 -0.3551 -0.7278 3615103 ACon1_001538 CC1CC(O)CC(C)(C)C1(O)/C=C/C(CO)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N03 compound treatment 66840.0 -1750.0 -0.05 81720.0 -18300.0 -0.47 -0.3736 -0.7828 3559788 ACon1_001539 CC(C)[C@@H]1CC[C@@](C)(O)[C@@H]2C[C@H](O)[C@@H]([C@H]21)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N04 compound treatment 78840.0 10300.0 0.32 104240.0 4270.0 0.11 0.303 0.9006 3615108 ACon1_001540 CC(C)(O)CCC(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4C(C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N05 compound treatment 13040.0 -55500.0 -1.72 19280.0 -80700.0 -2.1 -2.6995 -0.9952 3069522 ACon1_001541 COc1cc(/C=C/C(=O)N2CCC=CC2=O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N06 compound treatment 76480.0 7890.0 0.24 93520.0 -6450.0 -0.17 0.0544 0.1834 3615112 ACon1_001542 CCCC(O)c1ccc(C)cc1CCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N07 compound treatment 104280.0 35700.0 1.11 140000.0 40000.0 1.04 1.5174 0.9995 3615113 ACon1_001543 Cc1cc(C(=O)Oc2c(C)cc(C(=O)O)c(O)c2C)c(O)c(C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N08 compound treatment 75760.0 7170.0 0.22 96800.0 -3170.0 -0.08 0.0989 0.4171 3559245 ACon1_001544 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2c3c(O)cc4oc(cc(=O)c4c3O)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N09 mock treatment 72600.0 4010.0 0.12 89120.0 -10900.0 -0.28 -0.1115 -0.3617 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N10 mock treatment 67920.0 -668.0 -0.02 102240.0 2270.0 0.06 0.027 0.433 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N11 compound treatment 64280.0 -4310.0 -0.13 74280.0 -25700.0 -0.67 -0.5664 -0.832 3615116 ACon1_001545 COC(/C=C/CC\C=C\C(=O)O)C(O)C(C)C(O)/C(=C/C(C)C(=O)CCCC1CC(=O)NC(=O)C1)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N12 compound treatment 60560.0 -8030.0 -0.25 88240.0 -11700.0 -0.3 -0.3914 -0.9949 3615120 ACon1_001546 CCCC[C@H](O)[C@@H]1CC(=CC(=O)O1)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N13 mock treatment 64000.0 -4590.0 -0.14 100480.0 508.0 0.01 -0.0912 -0.6387 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N14 mock treatment 72240.0 3650.0 0.11 95680.0 -4290.0 -0.11 0.0012 0.0073 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N15 compound treatment 62520.0 -6070.0 -0.19 87680.0 -12300.0 -0.32 -0.3588 -0.9681 3615123 ACon1_001547 COC(=O)c1cccc(O)c1C(=O)c2c(O)cc(C)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N16 compound treatment 64520.0 -4070.0 -0.13 69440.0 -30500.0 -0.79 -0.6501 -0.8093 3615126 ACon1_001548 COc1ccc(cc1Cl)C(=O)NCCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N17 compound treatment 38520.0 -30100.0 -0.93 52640.0 -47300.0 -1.23 -1.5284 -0.9906 3615128 ACon1_001549 COc1cc(OC)c(cc1OC)c2coc3c4C=CC(C)(C)Oc4c(OC)cc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N18 compound treatment 53200.0 -15400.0 -0.48 69320.0 -30700.0 -0.8 -0.9003 -0.9699 2259 ACon1_001550 CN1CCc2cc3OCOc3cc2C(=O)Cc4ccc5OCOc5c4C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N19 compound treatment 27760.0 -40800.0 -1.27 29400.0 -70600.0 -1.83 -2.1911 -0.9836 3615132 ACon1_001551 COc1ccc2C[C@@H]3[C@H](COC3=O)[C@H](OC(=O)/C(=C\C)/C)c4cc(OC)c(OC)cc4-c2c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N20 compound treatment 43920.0 -24700.0 -0.76 59360.0 -40600.0 -1.06 -1.2866 -0.9875 3615136 ACon1_001552 CC(O)c1cncc2c(=O)n3CCc4c([nH]c5ccccc45)-c3cc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N21 compound treatment 28720.0 -39900.0 -1.24 41800.0 -58200.0 -1.51 -1.9422 -0.995 3615138 ACon1_001553 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@](C)(CO)C7[C@H](O)C[C@@]6(C)[C@]5(C)CC3)[C@H](O)[C@H](O)[C@H]1O[C@@H]9OC[C@@H](O)[C@H](O[C@@H]%10OC[C@](O)(CO)[C@H]%10O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N22 compound treatment 65000.0 -3590.0 -0.11 79120.0 -20900.0 -0.54 -0.4617 -0.8348 3615141 ACon1_001554 C/C=C(/C)\C(=O)OC1CCN2CC=C(COC(=O)C(O)(C(C)O)C(C)(C)O)C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N23 compound treatment 3160.0 -65400.0 -2.03 3840.0 -96100.0 -2.5 -3.1997 -0.9946 3614951 ACon1_001555 Cc1cc(O)c2C(=O)C3=C(C(O)C(O)C(O)C3O)C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 N24 compound treatment 33520.0 -35100.0 -1.09 57400.0 -42600.0 -1.11 -1.5505 -1.0 3615144 ACon1_001556 CO/C=C(/C1CC2N(CCC23C(=O)Nc4ccccc43)CC1C=C)\C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O01 compound treatment 33760.0 -34800.0 -1.08 45800.0 -54200.0 -1.41 -1.7583 -0.9914 3559328 ACon1_001557 CC1OC1(C)C(=O)O[C@@H]2CC[C@]3(C)CC(=O)C(=C(C)C)C[C@H]3[C@]2(C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O02 compound treatment 46920.0 -21700.0 -0.67 72920.0 -27100.0 -0.7 -0.9717 -0.9997 3559070 ACon1_001558 C[C@@H]1C[C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2O)[C@]5(C)[C@H](CCC=C5C)[C@@]1(C)CC[C@](C)(O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O03 compound treatment 47200.0 -21400.0 -0.66 86200.0 -13800.0 -0.36 -0.7216 -0.9582 1093459 ACon1_001559 COc1cc(CC2COC(=O)C2(O)Cc3ccc(O)c(OC)c3)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O04 compound treatment 41800.0 -26800.0 -0.83 46400.0 -53600.0 -1.39 -1.5712 -0.9695 3559095 ACon1_001560 C/C=C(/C)\C(=O)O[C@H]1C[C@]2(C)O[C@@H]2[C@H]3O[C@H]3C(=C)[C@@H](O)[C@H]4OC(=O)C(=C)[C@@H]41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O05 compound treatment 56160.0 -12400.0 -0.39 64560.0 -35400.0 -0.92 -0.9229 -0.9253 3558913 ACon1_001561 OC(=O)C[C@](O)(Cc1ccc(O)cc1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O06 compound treatment 51480.0 -17100.0 -0.53 61960.0 -38000.0 -0.99 -1.0732 -0.9574 3559222 ACon1_001562 COc1c(O)cc(cc1O)c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]4O[C@@H](C)[C@H](OC(=O)C)[C@@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O07 compound treatment 52040.0 -16500.0 -0.51 54320.0 -45700.0 -1.19 -1.2013 -0.9296 3557351 ACon1_001563 C[C@@H](OC(=O)C)[C@@H]1[C@]23O[C@@]3([C@H](O)c4c(O)c(ccc4C2=O)c5ccc6C(=O)[C@@]78O[C@@]8([C@H](O)c6c5O)C(=O)C[C@](C)(O)[C@@H]7[C@@H](C)OC(=O)C)C(=O)C[C@]1(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O08 compound treatment 54400.0 -14200.0 -0.44 61680.0 -38300.0 -0.99 -1.0144 -0.9326 3559212 ACon1_001564 CC(C)C(C)(O)C(=O)OCC1=CCN2CCC(O)C21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O09 compound treatment 7560.0 -61000.0 -1.89 9000.0 -91000.0 -2.36 -3.0085 -0.9939 3615151 ACon1_001565 C[C@@H]1C2[C@H](CC3[C@@H]4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)O[C@@]91CC[C@@](C)(CO[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)O9 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O10 compound treatment 40120.0 -28500.0 -0.88 53120.0 -46900.0 -1.22 -1.4845 -0.9875 3557334 ACon1_001566 CC(C)(C=C)[C@]12C[C@@H]3N([C@@H]2Nc4ccccc41)C(=O)/C(=C/c5cnc[nH]5)/NC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O11 mock treatment 60560.0 -8030.0 -0.25 79720.0 -20300.0 -0.53 -0.548 -0.9415 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O12 mock treatment 59480.0 -9110.0 -0.28 84560.0 -15400.0 -0.4 -0.4827 -0.9853 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O13 compound treatment 4440.0 -64100.0 -1.99 5800.0 -94200.0 -2.45 -3.1356 -0.9947 3554512 ACon1_001567 CO[C@H]1/C=C/C=C(\C)/C[C@H](C)[C@H](O)[C@H](C)/C=C(\C)/C=C(\OC)/C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)C(=O)\C=C\[C@H](C)[C@H](O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O14 compound treatment 61600.0 -6990.0 -0.22 72720.0 -27300.0 -0.71 -0.6538 -0.883 3180421 ACon1_001568 COc1ccc2[C@@H]3COc4cc(O)ccc4[C@@H]3Oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O15 compound treatment 61520.0 -7070.0 -0.22 71040.0 -28900.0 -0.75 -0.6864 -0.8767 3557322 ACon1_001569 CC/C=C/C=C/1\CO[C@@]2(CC[C@@H](CO)O2)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O16 compound treatment 65560.0 -3030.0 -0.09 73640.0 -26300.0 -0.68 -0.5501 -0.7966 3557362 ACon1_001570 CC(=O)c1nc2ccccc2c(=O)[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O17 compound treatment 4120.0 -64500.0 -2.0 5320.0 -94700.0 -2.46 -3.1514 -0.9947 3553815 ACon1_001571 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)C(O)[C@@H](C)C(=O)[C@@](C)(O)C(O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O18 compound treatment 49400.0 -19200.0 -0.59 42320.0 -57700.0 -1.5 -1.4796 -0.9181 3558879 ACon1_001572 CC(CO)C(=O)O[C@H]1C/C(=C/CC/C(=C/[C@H]2OC(=O)C(=C)[C@@H]21)/CO)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O19 compound treatment 4600.0 -64000.0 -1.98 5720.0 -94300.0 -2.45 -3.1336 -0.9945 3554106 ACon1_001573 CCC(C)(O)C(=O)O[C@@H]1[C@H]2[C@@H](C)[C@@H](O)[C@]3(O)OC[C@]42[C@H]3[C@@]5(C)[C@H](O)C(=O)C=C(C)[C@@H]5C[C@H]4OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O20 compound treatment 6640.0 -61900.0 -1.92 11880.0 -88100.0 -2.29 -2.9757 -0.9962 3559210 ACon1_001574 C[C@@]1(CO)CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3(CC4=C)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O21 compound treatment 93840.0 25300.0 0.78 108360.0 8390.0 0.22 0.7074 0.8709 3558433 ACon1_001575 CC1OC(OC2C(OC3OCC(O)C(O)C3O)C(OCCc4ccc(O)c(O)c4)OC(CO)C2OC(=O)/C=C/c5ccc(O)c(O)c5)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O22 compound treatment 4840.0 -63700.0 -1.98 5560.0 -94400.0 -2.45 -3.1313 -0.9942 3557365 ACon1_001576 CC(=O)O[C@@H]1C[C@@]2(C)[C@]3(CO3)[C@@H]1O[C@@H]4C=C(C)C(O)[C@H](O)[C@@]42C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O23 compound treatment 56880.0 -11700.0 -0.36 75840.0 -24100.0 -0.63 -0.6999 -0.9662 3558906 ACon1_001577 CCC(C)C(=O)OC/C=C(\C)/CC[C@H]1C(=C)C(O)CC2[C@@](C)(COC(=O)C)CC(O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 O24 compound treatment 46680.0 -21900.0 -0.68 65840.0 -34100.0 -0.89 -1.1071 -0.9913 3557395 ACon1_001578 CC1(CO)CC(O)CC2(C)C1CCC3=C2COC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P01 compound treatment 33280.0 -35300.0 -1.09 56080.0 -43900.0 -1.14 -1.58 -0.9998 1000475 ACon1_001579 O=c1ccc2cc3ccoc3cc2o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P02 compound treatment 46640.0 -21900.0 -0.68 51440.0 -48500.0 -1.26 -1.3725 -0.958 3615161 ACon1_001580 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(=O)O)[C@](C)(C5CC[C@]43C)C(=O)O)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P03 compound treatment 58960.0 -9630.0 -0.3 74480.0 -25500.0 -0.66 -0.6793 -0.9351 3553075 ACon1_001581 C[C@H]1[C@H](O)CCC2=CC(=O)C(=C[C@]12C)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P04 compound treatment 21400.0 -47200.0 -1.46 24480.0 -75500.0 -1.96 -2.4208 -0.9895 3615165 ACon1_001582 Cc1cc(O)c(C)c2Oc3c(C)c(O)c(O)c(C)c3OC(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P05 compound treatment 52400.0 -16200.0 -0.5 73000.0 -27000.0 -0.7 -0.8502 -0.9865 3615168 ACon1_001583 Oc1cccc2C(=O)Nc3ccccc3-c4nc5ccccc5c(=O)n4-c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P06 compound treatment 56640.0 -11900.0 -0.37 64640.0 -35300.0 -0.92 -0.9109 -0.9202 3615170 ACon1_001584 CC1CC(OC=O)C2C(C)C(CCC2(C)C31CCC4(COC(=O)C4)O3)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P07 compound treatment 14400.0 -54200.0 -1.68 16960.0 -83000.0 -2.16 -2.7124 -0.9923 3615172 ACon1_001585 COC1CC(OC2C(C)OC(CC2OC)OC3C(C)OC(CC3OC)OC4C(C)OC(CC4OC)O[C@H]5CC[C@]6(C)C7CC(OC(=O)c8ccccc8)[C@]9(C)[C@@](O)(CC[C@]9(O)[C@]7(O)CC=C6C5)C(=O)C)OC(C)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P08 compound treatment 56480.0 -12100.0 -0.38 69920.0 -30100.0 -0.78 -0.8174 -0.9436 3615176 ACon1_001586 O[C@@H]1[C@@H](O)[C@H](Oc2c(O)c(c(O)cc2c3ccccc3)c4ccccc4)O[C@@H]([C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P09 compound treatment 49880.0 -18700.0 -0.58 62720.0 -37300.0 -0.97 -1.0943 -0.9699 3615180 ACon1_001587 Cc1cc2C(=O)c3ccccc3C(=O)c2cc1O[C@@H]4O[C@H](CO[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P10 compound treatment 35440.0 -33100.0 -1.03 68360.0 -31600.0 -0.82 -1.307 -0.9939 3615183 ACon1_001588 CC(=O)[C@@]12C[C@@H](CC[C@@]2(C)CC[C@@H]1O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P11 mock treatment 59880.0 -8710.0 -0.27 85360.0 -14600.0 -0.38 -0.4592 -0.986 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P12 mock treatment 57840.0 -10700.0 -0.33 84840.0 -15100.0 -0.39 -0.5135 -0.9966 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P13 compound treatment 18760.0 -49800.0 -1.54 29440.0 -70500.0 -1.83 -2.3875 -0.9964 3615185 ACon1_001589 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)CO[C@@H](O[C@H]3[C@H](C)O[C@@H](O[C@@H]4[C@@H](O)[C@@H](O)CO[C@H]4OC(=O)[C@@]56CCC(C)(C)C[C@H]6C7=CCC8[C@@]9(C)C[C@H](O)[C@H](O[C@@H]%10O[C@@H]([C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@@](C)(CO)C9[C@H](O)C[C@@]8(C)[C@]7(C)C[C@H]5O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P14 compound treatment 12040.0 -56500.0 -1.75 18080.0 -81900.0 -2.13 -2.7435 -0.9953 3615189 ACon1_001590 COc1cc(nc(/C=N/O)c1S(=O)C)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P15 compound treatment 51000.0 -17600.0 -0.54 51360.0 -48600.0 -1.26 -1.2785 -0.9294 3557312 ACon1_001591 CC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC3CCC(O3)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P16 compound treatment 46360.0 -22200.0 -0.69 66280.0 -33700.0 -0.88 -1.106 -0.993 3615194 ACon1_001592 CC(C)(C=C)C12CC3N(C2Nc4ccccc41)C(=O)C(Cc5c[nH]cn5)NC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P17 compound treatment 45960.0 -22600.0 -0.7 60200.0 -39800.0 -1.03 -1.2265 -0.9821 3558732 ACon1_001593 O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P18 compound treatment 40160.0 -28400.0 -0.88 49720.0 -50300.0 -1.31 -1.5461 -0.9816 3615196 ACon1_001594 COC(=O)C1(CO)C/2CCN(C\C2=C/C)Cc3c1[nH]c4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P19 compound treatment 50880.0 -17700.0 -0.55 67880.0 -32100.0 -0.83 -0.9776 -0.9794 3615200 ACon1_001595 C/C(=C\CCC(C)(O)C=C)/C(=O)OC1C2OC2(C)C3C(OC4OC(COC5OC(CO)C(O)C(O)C5O)C(O)C(O)C4O)OC=CC13O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P20 compound treatment 46720.0 -21900.0 -0.68 62600.0 -37400.0 -0.97 -1.1657 -0.9845 2096349 ACon1_001596 COc1cc2CCN(C)C3(Cc4ccc5OCOc5c4C3=O)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P21 compound treatment 67080.0 -1510.0 -0.05 91040.0 -8930.0 -0.23 -0.1971 -0.8327 1054272 ACon1_001597 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P22 compound treatment 26000.0 -42600.0 -1.32 32040.0 -67900.0 -1.77 -2.1812 -0.9897 1874510 ACon1_001598 CC1C2C(CC3C4CC=C5CC(O)CCC5(C)C4CCC23C)OC61CCC(C)CN6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P23 compound treatment 38800.0 -29800.0 -0.92 58160.0 -41800.0 -1.09 -1.4208 -0.9967 3615206 ACon1_001599 CC1OC(O[C@H]2[C@@H](O)C[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)CC[C@@]6(CC[C@]54C)C(=O)OC7OC(C)C(OC8OCC(OC9OCC(O)C(OC%10OCC(O)C(O)C%10O)C9O)C(O)C8O)C(O)C7O)[C@]2(C)CO)C(O)C(OC%11OC(CO)C(O)C(O)C%11O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2294 P24 compound treatment 31520.0 -37100.0 -1.15 50320.0 -49700.0 -1.29 -1.7244 -0.9983 1707947 ACon1_001600 CN1CCc2cc3OCOc3cc2C1C4OC(=O)c5c6OCOc6ccc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A01 compound treatment 56520.0 -79200.0 -2.46 43280.0 -73700.0 -1.91 -3.0901 -0.9924 3615211 ACon1_001601 COc1cc2CCN(C)C3Cc4ccc(O)c(O)c4-c(c1OC)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A02 compound treatment 55480.0 -80300.0 -2.49 49560.0 -67400.0 -1.75 -2.9975 -0.9853 3615213 ACon1_001602 CC1OC(Oc2cc(O)c(C3OC(C)C(O)C(O)C3O)c4oc(cc(=O)c24)c5ccc(O)cc5)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A03 compound treatment 19000.0 -117000.0 -3.62 19440.0 -97500.0 -2.53 -4.3501 -0.9848 3484788 ACon1_001603 CCC(C)C1NC(=O)C2CCCN2C(=O)C(CC=C)OC(=O)CCNC(=O)C(C)N(C)C(=O)C(C(C)C)N(C)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A04 compound treatment 75000.0 -60800.0 -1.88 61160.0 -55800.0 -1.45 -2.3567 -0.9917 3615215 ACon1_001604 COc1cc(cc(OC)c1O)C(=O)OC[C@@]2(O)CO[C@H](OC3C(O)C(O)C(Oc4cc(OC)c(OC)c(OC)c4)OC3CO)[C@@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A05 compound treatment 83040.0 -52700.0 -1.63 66560.0 -50400.0 -1.31 -2.0813 -0.994 3557487 ACon1_001605 CC1(O)CC2(CC1CCC23)CC(=O)C4C(CO)(CCCC34C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A06 compound treatment 91160.0 -44600.0 -1.38 68760.0 -48200.0 -1.25 -1.863 -0.9988 3615219 ACon1_001606 CCCCCC(=O)CC(O)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A07 compound treatment 87800.0 -48000.0 -1.49 76000.0 -41000.0 -1.06 -1.8036 -0.9866 3553900 ACon1_001607 CC1[C@H]2[C@@H](CC1=O)C(=C)C[C@@H](O)[C@@H]3[C@@H]2OC(=O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A08 compound treatment 35200.0 -101000.0 -3.12 12760.0 -104000.0 -2.71 -4.1179 -0.9976 3615221 ACon1_001608 CC1(CCCC2(C)C1C(O)CC3(CC4(O)CC=C32)C(=O)C4=C)C(=O)OC5OC(CO)C(O)C(O)C5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A09 compound treatment 84680.0 -51100.0 -1.58 68120.0 -48900.0 -1.27 -2.0167 -0.994 3615223 ACon1_001609 C[C@@]1(O)C[C@@H](O)C[C@]2(C)CC[C@H](CC12)C(=C)C(=O)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A10 compound treatment 78920.0 -56800.0 -1.76 67360.0 -49600.0 -1.29 -2.1569 -0.9882 3615227 ACon1_001610 C[C@@]12CCC[C@@]3(C)C2[C@@H](C[C@@]4(CO4)[C@]3(O)CCc5ccoc5)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A11 compound treatment 71840.0 -63900.0 -1.98 66040.0 -50900.0 -1.32 -2.3363 -0.9808 1088391 ACon1_001611 CC1=CC(=O)c2c(O)cccc2C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A12 compound treatment 100680.0 -35100.0 -1.09 61360.0 -55600.0 -1.44 -1.7904 -0.9902 3615231 ACon1_001612 COC(/C=C/C(OC(=O)C)C(C)OC(=O)C)C(O)C1CC=CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A13 mock treatment 113880.0 -21900.0 -0.68 77560.0 -39400.0 -1.02 -1.2035 -0.98 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A14 mock treatment 108080.0 -27700.0 -0.86 82720.0 -34300.0 -0.89 -1.2358 -0.9998 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A15 compound treatment 59720.0 -76000.0 -2.36 59920.0 -57100.0 -1.48 -2.7142 -0.9751 3615235 ACon1_001613 OC1Cc2c(O)c3C(C(O)C(Oc3cc2OC1c4ccc(O)c(O)c4)c5ccc(O)c(O)c5)c6ccc(O)cc6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A16 compound treatment 26440.0 -109000.0 -3.39 21240.0 -95700.0 -2.49 -4.154 -0.9885 3615238 ACon1_001614 CC(C)/C=C/C=C(\C)/CC/C=C(\C)/CCOc1c(O)cc2C(=O)NCc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A17 compound treatment 11320.0 -124000.0 -3.86 12040.0 -105000.0 -2.73 -4.6543 -0.9856 3615241 ACon1_001615 C[C@@H]1O[C@@H](OC(=O)c2c(C)coc2C)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A18 compound treatment 51840.0 -83900.0 -2.6 43240.0 -73700.0 -1.92 -3.1933 -0.9887 3615246 ACon1_001616 C[C@@H]1O[C@@H](OC2C(O)C(O)C(OC3C(O)COC(O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7C8CC(C)(C)CC[C@@]8(CC[C@]76C)C(=O)OC9OC(CO)C(O)C(O)C9O)C4(C)C)C3O)OC2C(=O)O)[C@H](O)[C@H](OC%10OC(CO)C(O)C(O)C%10O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A19 compound treatment 112520.0 -23200.0 -0.72 90640.0 -26300.0 -0.68 -0.993 -0.9997 3615250 ACon1_001617 OC1CCC(=O)c2c(O)cccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A20 compound treatment 14320.0 -121000.0 -3.76 13680.0 -103000.0 -2.68 -4.5585 -0.9863 3559151 ACon1_001618 CC(CCC1(O)OC2CC3C4CCC5CC(CCC5(C)C4CCC3(C)C2C1C)OC6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)COC8OC(CO)C(O)C(O)C8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A21 compound treatment 118520.0 -17200.0 -0.53 97800.0 -19200.0 -0.5 -0.73 -0.9994 3615252 ACon1_001619 OC(=O)CCCCCCC/C=C\CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A22 compound treatment 109560.0 -26200.0 -0.81 89400.0 -27600.0 -0.72 -1.0806 -0.9981 1018507 ACon1_001620 Oc1ccc(C=O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A23 compound treatment 78000.0 -57800.0 -1.79 54560.0 -62400.0 -1.62 -2.4122 -0.9988 3615257 ACon1_001621 CC(=O)OC(CCCCc1ccc(O)c(O)c1)CCc2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 A24 compound treatment 72680.0 -63100.0 -1.95 68080.0 -48900.0 -1.27 -2.2804 -0.9782 3559182 ACon1_001622 COc1cc(cc(OC)c1O)C2OC[C@@H]3[C@H](OC[C@H]23)c4cc(OC)c(O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B01 compound treatment 105440.0 -30300.0 -0.94 80360.0 -36600.0 -0.95 -1.337 -1.0 3615259 ACon1_001623 COc1cc(/C=C/C(=O)O[C@@H]2[C@H](O)[C@@H](OC3OC(CO)C(O)C(O)C3O)[C@H](C)O[C@H]2OCC4OC(Oc5c(oc6cc(O)cc(O)c6c5=O)c7ccc(O)cc7)C(O)C(O)C4O)cc(OC)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B02 compound treatment 119000.0 -16800.0 -0.52 91600.0 -25400.0 -0.66 -0.8334 -0.993 3615262 ACon1_001624 OCCCCCCCC=C(C(=O)O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B03 compound treatment 103800.0 -32000.0 -0.99 95880.0 -21100.0 -0.55 -1.0878 -0.9611 3615264 ACon1_001625 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B04 compound treatment 17760.0 -118000.0 -3.66 10240.0 -107000.0 -2.77 -4.5463 -0.9907 3615266 ACon1_001626 CN1C(=O)c2ccccc2-n3c(nc4ccccc4c3=O)[C@]51O[C@H]5c6ccccc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B05 compound treatment 5320.0 -130000.0 -4.04 4560.0 -112000.0 -2.92 -4.9232 -0.9873 3615270 ACon1_001627 COc1c(Cc2ccccc2O)c(O)c(Cc3ccccc3O)c(O)c1C(=O)CCc4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B06 compound treatment 7680.0 -128000.0 -3.97 6440.0 -111000.0 -2.87 -4.837 -0.9874 3615272 ACon1_001628 CCC(C)CC(C)/C=C\C1OC2=C(C(O)C1O)C(=O)OC2(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B07 compound treatment 83640.0 -52100.0 -1.61 85760.0 -31200.0 -0.81 -1.7154 -0.9492 3615275 ACon1_001629 CC(=CCCC(C)(O)C(O)Cc1cc(cc(CC=C(C)C)c1O)C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B08 compound treatment 95760.0 -40000.0 -1.24 85000.0 -32000.0 -0.83 -1.4638 -0.9811 3054974 ACon1_001630 COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]21 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B09 compound treatment 113920.0 -21800.0 -0.68 99160.0 -17800.0 -0.46 -0.8058 -0.9828 3615278 ACon1_001631 CC(=O)c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(/C=C/C(C)(C)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B10 compound treatment 101360.0 -34400.0 -1.07 85600.0 -31400.0 -0.82 -1.3301 -0.9912 3559815 ACon1_001632 COc1cc(ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c3oc4cc(O)cc(O)c4c(=O)c3O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B11 compound treatment 54120.0 -81600.0 -2.53 59160.0 -57800.0 -1.5 -2.8509 -0.969 3559060 ACon1_001633 COc1cc2OC[C@@H]3Oc4c5C[C@H](Oc5ccc4C(=O)[C@]3(O)c2cc1OC)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B12 compound treatment 31320.0 -104000.0 -3.24 27200.0 -89800.0 -2.33 -3.9376 -0.9871 3076873 ACon1_001634 COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)/C=C/c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B13 mock treatment 160080.0 24300.0 0.75 131320.0 14300.0 0.37 0.7964 0.9474 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B14 mock treatment 137040.0 1280.0 0.04 117080.0 108.0 0.0 0.03 0.7554 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B15 compound treatment 124040.0 -11700.0 -0.36 106840.0 -10100.0 -0.26 -0.443 -0.9875 3615283 ACon1_001635 COc1cc(oc(=O)c1C)C(C)C=C(C)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B16 compound treatment 81200.0 -54600.0 -1.69 67400.0 -49600.0 -1.29 -2.1062 -0.991 3615285 ACon1_001636 OC(=O)c1cc(O)c(O)c(O)c1c2c(O)c(O)c3oc(=O)c4cc(O)c(O)c5oc(=O)c2c3c45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B17 compound treatment 103960.0 -31800.0 -0.99 96680.0 -20300.0 -0.53 -1.0696 -0.9571 3615286 ACon1_001637 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(O)C6O)C(=O)O)C(CO)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)OC7OC(CO)C(OC8OC(CO)C(O)C(O)C8O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B18 compound treatment 99120.0 -36600.0 -1.14 107440.0 -9530.0 -0.25 -0.9779 -0.8416 3615290 ACon1_001638 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@H]4O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c(oc3c2)c7ccc(O)c(O)c7)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B19 compound treatment 121760.0 -14000.0 -0.43 104280.0 -12700.0 -0.33 -0.54 -0.9908 3615295 ACon1_001639 COc1cc2c(cc1O)C(=O)CC3C(C)(C)C(=O)CCC32C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B20 compound treatment 118600.0 -17200.0 -0.53 129440.0 12500.0 0.32 -0.1469 -0.236 3615297 ACon1_001640 CC1(CCO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC3C(=CCC4[C@@](C)(CCC[C@]34C)C(=O)O)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B21 compound treatment 120720.0 -15000.0 -0.47 101040.0 -15900.0 -0.41 -0.6223 -0.9983 3615299 ACon1_001641 COC1(C)C(O)C(=O)C(=C(Oc2cc(C)cc(O)c2C)C1=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B22 compound treatment 127120.0 -8640.0 -0.27 127360.0 10400.0 0.27 0.0015 0.004 3615301 ACon1_001642 COc1cc(/C=C/COC2OC(CO)C(O)C(O)C2O)cc3C(CO)C(Oc31)c4ccc(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B23 compound treatment 136280.0 517.0 0.02 107080.0 -9890.0 -0.26 -0.1704 -0.6617 3615306 ACon1_001643 COc1cc2oc(cc(=O)c2c(OC)c1OC)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 B24 compound treatment 100200.0 -35600.0 -1.1 85560.0 -31400.0 -0.82 -1.3563 -0.9891 3558267 ACon1_001644 C[C@@]12CC[C@@H](O)C(=C)C2C[C@@H](CC1)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C01 compound treatment 75560.0 -60200.0 -1.87 65200.0 -51800.0 -1.35 -2.2702 -0.9871 3615308 ACon1_001645 COC(=O)[C@@H]1C[C@@]2(C=CC[N+]3([O-])CC[C@]45[C@H]23)C(C)[C@]51Nc6ccccc64 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C02 compound treatment 71520.0 -64200.0 -1.99 53800.0 -63200.0 -1.64 -2.5681 -0.9954 3615312 ACon1_001646 OCC1OC(OCC2OC(OC(CCc3ccccc3)CC(=O)CCc4ccccc4)C(O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C03 compound treatment 54240.0 -81500.0 -2.53 40320.0 -76700.0 -1.99 -3.1944 -0.9931 3554647 ACon1_001647 COC(=O)C(=C)[C@]1(O[C@@]/23CC[C@@](C)(O)CC1=O)[C@H](C[C@@]3(C)OC(=O)\C2=C\C)OC(=O)C(=C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C04 compound treatment 103520.0 -32200.0 -1.0 76880.0 -40100.0 -1.04 -1.443 -0.9998 3615314 ACon1_001648 COc1cc(cc(OC)c1O)C(=O)OC[C@@]2(O)CO[C@H](OC3C(O)C(O)C(OC(C)/C=C/C4(O)C(C)CC(O)CC4(C)C)OC3CO)[C@@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C05 compound treatment 122080.0 -13700.0 -0.42 103080.0 -13900.0 -0.36 -0.555 -0.9968 3553387 ACon1_001649 CC(=O)OC1CC2C(C=C1C)C(C(CC2(C)O)OC(=O)/C(=C/CO)/CO)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C06 compound treatment 112440.0 -23300.0 -0.72 96000.0 -21000.0 -0.54 -0.8963 -0.9903 3615318 ACon1_001650 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@H]1C)C(=O)OC6OC(COC7OC(CO)C(O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)C(O)C7O)C(O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C07 compound treatment 7160.0 -129000.0 -3.98 7040.0 -110000.0 -2.86 -4.8373 -0.9867 3558295 ACon1_001651 CC(C)c1cc2CCC3C(C)(C)C[C@H](O)C[C@]3(C)c2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C08 compound treatment 92680.0 -43100.0 -1.33 71800.0 -45200.0 -1.17 -1.7738 -0.9979 3615325 ACon1_001652 CC1OC(OC2C(O)C(O)C(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)OC8OC(CO)C(O)C(O)C8O)C3(C)C)OC2C(=O)O)C(OC9OCC(O)C(O)C9O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C09 compound treatment 115280.0 -20500.0 -0.63 93640.0 -23300.0 -0.61 -0.8774 -0.9997 3558212 ACon1_001653 C[C@@]1(O)CCC2[C@H](OC(=O)C2=C)[C@@H]3[C@H]1C[C@H](O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C10 compound treatment 82680.0 -53100.0 -1.64 69840.0 -47100.0 -1.22 -2.0289 -0.9895 3615328 ACon1_001654 CC1OC(OCC2OC(OCC3(C)C(O)CCC4(C)C3CCC5(C)C4CCC6C7=CC(C)(C)CCC7(CCC65C)C(=O)O)C(O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C11 mock treatment 84840.0 -50900.0 -1.58 103120.0 -13900.0 -0.36 -1.3702 -0.8467 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C12 mock treatment 140640.0 4880.0 0.15 123800.0 6830.0 0.18 0.2323 0.9968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C13 compound treatment 134680.0 -1080.0 -0.03 98600.0 -18400.0 -0.48 -0.3613 -0.7549 3553489 ACon1_001655 CC(C)[C@@H](NC(=O)C)C(=O)O[C@H]1CCC(C)(C)[C@@H]2CCC3=C(COC3=O)[C@@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C14 compound treatment 21360.0 -114000.0 -3.54 13040.0 -104000.0 -2.7 -4.416 -0.991 3615331 ACon1_001656 CCCCCCCCC/C=C/CCCCC(=O)C1C(=O)CCC(O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C15 mock treatment 118160.0 -17600.0 -0.55 112840.0 -4130.0 -0.11 -0.4616 -0.8304 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C16 mock treatment 106360.0 -29400.0 -0.91 90880.0 -26100.0 -0.68 -1.1236 -0.9894 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C17 compound treatment 78480.0 -57300.0 -1.77 74840.0 -42100.0 -1.09 -2.0291 -0.973 3615336 ACon1_001657 OC(=O)C(OC(=O)/C=C/c1ccc(O)c(O)c1)C(OC(=O)/C=C/c2ccc(O)c(O)c2)C(OC(=O)/C=C/c3ccc(O)c(O)c3)C(OC(=O)/C=C/c4ccc(O)c(O)c4)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C18 compound treatment 26640.0 -109000.0 -3.38 15960.0 -101000.0 -2.62 -4.2467 -0.9922 3615339 ACon1_001658 CC(C)/C=C/C=C(\C)/CCC\C(=C\COc1c(O)cc2C(=O)NCc2c1O)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C19 compound treatment 6560.0 -129000.0 -4.0 5840.0 -111000.0 -2.89 -4.8725 -0.9871 3554116 ACon1_001659 CCC(C)[C@@H]1N(C)C(=O)[C@@H](CC(C)C)OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C20 compound treatment 113360.0 -22400.0 -0.69 88800.0 -28200.0 -0.73 -1.0084 -0.9996 3615343 ACon1_001660 C[C@H]1O[C@@H](O[C@H]2C[C@@H]3[C@@H](CC2(C)C)C4=CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(C=O)C6CC[C@@]5(C)[C@]4(C)CC3=O)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C21 compound treatment 111680.0 -24100.0 -0.75 99600.0 -17400.0 -0.45 -0.8468 -0.971 3558893 ACon1_001661 Oc1ccc(CCNC(=O)/C=C/c2ccc(O)c(O)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C22 compound treatment 7680.0 -128000.0 -3.97 8080.0 -109000.0 -2.83 -4.8068 -0.9862 3559174 ACon1_001662 OC[C@H]1O[C@@H](Oc2cc(O)cc3OC(CC(=O)c23)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C23 compound treatment 68480.0 -67300.0 -2.08 83000.0 -34000.0 -0.88 -2.0983 -0.9268 3615348 ACon1_001663 OCC(=C)C(=O)O[C@H]1CC(=C)[C@@H]2C[C@H](O)C(=C)[C@@H]2[C@H]3OC(=O)C(CN4CCCC4C(=O)O)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 C24 compound treatment 6800.0 -129000.0 -4.0 6320.0 -111000.0 -2.88 -4.8584 -0.987 3559220 ACon1_001664 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H]1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D01 compound treatment 69400.0 -66400.0 -2.06 82600.0 -34400.0 -0.89 -2.0855 -0.9303 3615352 ACon1_001665 C/C(=C\Cc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc3ccc(=O)oc13)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D02 compound treatment 134120.0 -1640.0 -0.05 129560.0 12600.0 0.33 0.1953 0.59 3615355 ACon1_001666 O[C@@H]1CC(=O)c2cccc(O)c2[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D03 compound treatment 10280.0 -125000.0 -3.89 9360.0 -108000.0 -2.8 -4.7264 -0.9869 3615359 ACon1_001667 OCCCCC/C=C\C/C=C\C(O)CC1CCC(CC(=O)O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D04 compound treatment 23280.0 -112000.0 -3.49 19200.0 -97800.0 -2.54 -4.2607 -0.9879 3615363 ACon1_001668 COCC1OC(OC(C)(C)C2CCC3(C)C=C(CCC3O2)C4CCC5C4(C)CC(O)C6OC(CCC56C)C(C)(C)OC7OC(CO)C(O)C(O)C7NC(=O)C)C(NC(=O)C)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D05 compound treatment 153920.0 18200.0 0.56 131240.0 14300.0 0.37 0.66 0.9795 3615365 ACon1_001669 Cc1cc(O)c2c(=O)c3c(cc(O)cc3oc2c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D06 compound treatment 7360.0 -128000.0 -3.98 7200.0 -110000.0 -2.85 -4.83 -0.9867 3615368 ACon1_001670 CCC(C)C1NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)CC(CCCCCCCCCC(C)C)OC1=O)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D07 compound treatment 128320.0 -7440.0 -0.23 130960.0 14000.0 0.36 0.0939 0.2182 3615370 ACon1_001671 CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H](O)COc2c3ccoc3cc4oc(=O)ccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D08 compound treatment 147200.0 11400.0 0.35 139880.0 22900.0 0.6 0.6715 0.9693 3554551 ACon1_001672 COC(=O)[C@]1(C)CC[C@@H](OC(=O)C)[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3([C@H](OC(=O)C)C4=C)[C@H](CC12)OC(=O)[C@]5(C)O[C@@H]5C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D09 compound treatment 66200.0 -69600.0 -2.16 70600.0 -46400.0 -1.2 -2.376 -0.9622 3615375 ACon1_001673 ON1CCCCCNC(=O)CCC(=O)N(O)CCCCNC(=O)CCC(=O)N(O)CCCCNC(=O)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D10 compound treatment 9480.0 -126000.0 -3.91 8320.0 -109000.0 -2.82 -4.763 -0.9872 3559785 ACon1_001674 COc1ccc(cc1)C2CC(=O)c3c(O)c(CC=C(C)C)c(O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D11 mock treatment 150000.0 14200.0 0.44 147840.0 30900.0 0.8 0.8791 0.9604 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D12 mock treatment 185120.0 49400.0 1.53 142360.0 25400.0 0.66 1.5478 0.9293 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D13 compound treatment 116600.0 -19200.0 -0.59 88600.0 -28400.0 -0.74 -0.9411 -0.9942 3559167 ACon1_001675 COc1cc(/C=C/CO)cc2[C@@H](CO)[C@H](Oc21)c3ccc(OC4OC(CO)C(O)C(O)C4O)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D14 compound treatment 9480.0 -126000.0 -3.91 8840.0 -108000.0 -2.81 -4.7534 -0.9868 3615378 ACon1_001676 CCCCCCc1cc(O)c(C)c(OC(=O)C)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D15 mock treatment 147760.0 12000.0 0.37 147880.0 30900.0 0.8 0.8307 0.9387 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D16 mock treatment 151560.0 15800.0 0.49 136280.0 19300.0 0.5 0.7009 0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D17 compound treatment 128680.0 -7080.0 -0.22 127600.0 10600.0 0.28 0.0401 0.1137 3615380 ACon1_001677 COc1cc(oc(=O)c1C)C(C)CC(C)(O)CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D18 compound treatment 133280.0 -2480.0 -0.08 123000.0 6030.0 0.16 0.0564 0.323 3615382 ACon1_001678 COC(=O)C[C@H]1C(C)(C)[C@H](OC(=O)C)[C@]2(O)CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D19 compound treatment 11160.0 -125000.0 -3.86 9400.0 -108000.0 -2.8 -4.7063 -0.9874 3559250 ACon1_001679 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](OC6OC(C(O)C(O)C6O)C(=O)O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D20 compound treatment 7440.0 -128000.0 -3.98 5680.0 -111000.0 -2.89 -4.8562 -0.9878 3615386 ACon1_001680 COc1ccc(/C=C/c2cc(OC)cc(O)c2CC=C(C)C)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D21 compound treatment 97840.0 -37900.0 -1.18 78760.0 -38200.0 -0.99 -1.5329 -0.9965 3615390 ACon1_001681 CC/C=C\CC/1C(=O)C=C\C1=C\CCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D22 compound treatment 124680.0 -11100.0 -0.34 126680.0 9710.0 0.25 -0.0644 -0.1513 3615393 ACon1_001682 CC1C2C(O)C(=O)C3(C)C(CCC4/C(=C(\CCC=C(C)C)/C(=O)O)/C(CC43C)OC(=O)C)C2(C)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D23 compound treatment 13240.0 -123000.0 -3.8 11960.0 -105000.0 -2.73 -4.6137 -0.9869 3559227 ACon1_001683 COc1cc(O[C@@H]2O[C@H](CO[C@H]3OC[C@](O)(COC(=O)c4ccc(O)c(OC)c4)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 D24 compound treatment 96320.0 -39400.0 -1.22 100880.0 -16100.0 -0.42 -1.1598 -0.8979 3615396 ACon1_001684 CCN1C[C@]2(C)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@](O)(C[C@@H]5OC)C6[C@@H](OC)C32)[C@@H]61 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E01 mock treatment 65440.0 -70300.0 -2.18 68720.0 -48300.0 -1.25 -2.4272 -0.9655 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E02 mock treatment 92160.0 -43600.0 -1.35 74160.0 -42800.0 -1.11 -1.7419 -0.9953 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E03 compound treatment 10440.0 -125000.0 -3.88 8200.0 -109000.0 -2.83 -4.7442 -0.9878 3557617 ACon1_001685 CC1CC[C@H](OC(=O)c2ccoc2)[C@@]3(C)[C@H](C[C@@H]4C[C@]13OC4(C)C)OC(=O)c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E04 compound treatment 86440.0 -49300.0 -1.53 67800.0 -49200.0 -1.28 -1.984 -0.996 3615401 ACon1_001686 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@@H](OC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E05 compound treatment 110960.0 -24800.0 -0.77 99200.0 -17800.0 -0.46 -0.8699 -0.9703 3557658 ACon1_001687 COc1c(oc2cc(O)cc(O)c2c1=O)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E06 compound treatment 100200.0 -35600.0 -1.1 80320.0 -36700.0 -0.95 -1.4525 -0.9974 3615406 ACon1_001688 CO[C@@H]1[C@@H](C)O[C@@H](OC2CC3C(=CC2(C)C=C)CCC4C(C)(C)C(CCC34C)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E07 compound treatment 12920.0 -123000.0 -3.81 11880.0 -105000.0 -2.73 -4.6222 -0.9867 3552666 ACon1_001689 C[C@@H]1C[C@H]2OCC3=CCC[C@@H]([C@@]23CO)[C@]1(CC(O)c4ccoc4)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E08 compound treatment 104560.0 -31200.0 -0.97 87400.0 -29600.0 -0.77 -1.2269 -0.9935 3615410 ACon1_001690 COC1OC(O)C(O)C21CC[C@@]3(O2)[C@H](C)C[C@H]4OC(=O)[C@@]5(C)CCC[C@]3(C)C45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E09 mock treatment 123960.0 -11800.0 -0.37 84920.0 -32100.0 -0.83 -0.8475 -0.9317 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E10 mock treatment 108240.0 -27500.0 -0.85 95000.0 -22000.0 -0.57 -1.0067 -0.981 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E11 compound treatment 112040.0 -23700.0 -0.74 96960.0 -20000.0 -0.52 -0.8874 -0.9856 3615414 ACon1_001691 CC(C)CCCC(C)(O)c1ccc(cc1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E12 compound treatment 124520.0 -11200.0 -0.35 101760.0 -15200.0 -0.4 -0.5258 -0.998 3615416 ACon1_001692 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)CC[C@@]31O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E13 compound treatment 98960.0 -36800.0 -1.14 81960.0 -35000.0 -0.91 -1.4496 -0.9937 905 ACon1_001693 CO[C@@H]1[C@@H](OC(=O)N)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E14 compound treatment 83720.0 -52000.0 -1.61 69680.0 -47300.0 -1.23 -2.0091 -0.991 3615420 ACon1_001694 CC1CCC2(C)C(CC(O)C(O)C2(O)CO)C1(C)CCc3ccoc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E15 compound treatment 95000.0 -40800.0 -1.26 78400.0 -38600.0 -1.0 -1.6017 -0.9934 3615422 ACon1_001695 OCC1OC(C(OC(=O)c2cc(O)c(O)c(O)c2)C(O)C1O)c3c(O)cc(O)c4c(=O)cc(oc34)c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E16 compound treatment 91000.0 -44800.0 -1.39 81240.0 -35700.0 -0.93 -1.6372 -0.9809 3615425 ACon1_001696 CCCCCC[C@H](O)/C=C/CC1=C(O)CC[C@H](O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E17 mock treatment 136560.0 797.0 0.02 93840.0 -23100.0 -0.6 -0.4075 -0.6775 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E18 mock treatment 121040.0 -14700.0 -0.46 99360.0 -17600.0 -0.46 -0.6461 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E19 compound treatment 122880.0 -12900.0 -0.4 95120.0 -21900.0 -0.57 -0.6837 -0.9851 3558102 ACon1_001697 COc1ccc(cc1OC)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E20 compound treatment 8640.0 -127000.0 -3.94 7040.0 -110000.0 -2.86 -4.8049 -0.9875 3558556 ACon1_001698 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E21 compound treatment 108560.0 -27200.0 -0.84 91680.0 -25300.0 -0.66 -1.0607 -0.9924 3615429 ACon1_001699 OC(CCc1ccc(O)c(O)c1)CC(=O)CCc2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E22 compound treatment 134280.0 -1480.0 -0.05 94520.0 -22500.0 -0.58 -0.445 -0.7604 3559178 ACon1_001700 CC1(CC(O)C2C=COC(OC3OC(CO)C(O)C(O)C3O)C21)OC(=O)/C=C/c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E23 compound treatment 114800.0 -21000.0 -0.65 102320.0 -14700.0 -0.38 -0.7285 -0.9676 3615432 ACon1_001701 CC(=O)NC(Cc1c[nH]c2cc(Cl)ccc12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 E24 compound treatment 71840.0 -63900.0 -1.98 67680.0 -49300.0 -1.28 -2.3061 -0.9777 3557371 ACon1_001702 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O)c2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F01 mock treatment 95160.0 -40600.0 -1.26 105520.0 -11500.0 -0.3 -1.1 -0.8509 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F02 mock treatment 134880.0 -883.0 -0.03 142880.0 25900.0 0.67 0.4567 0.6778 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F03 compound treatment 106840.0 -28900.0 -0.9 98320.0 -18700.0 -0.48 -0.9764 -0.9583 3615435 ACon1_001703 C[C@H](CC/C=C(\C)/C(=O)O)[C@H]1CC(O)[C@@]2(C)C3CC[C@@H]4[C@]5(C[C@@]35CC(O)[C@]12C)CC[C@H](O[C@@H]6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F04 compound treatment 102040.0 -33700.0 -1.04 89800.0 -27200.0 -0.71 -1.2381 -0.9818 3615438 ACon1_001704 CC1OC(OC2C(O)C(O)C(CO)OC2Oc3c(oc4cc(OC5OC(C)C(O)C(O)C5O)cc(O)c4c3=O)c6ccc(O)c(O)c6)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F05 compound treatment 116280.0 -19500.0 -0.6 109120.0 -7850.0 -0.2 -0.5711 -0.8963 3615441 ACon1_001705 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(C)OC(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F06 compound treatment 151120.0 15400.0 0.48 113000.0 -3970.0 -0.1 0.2635 0.5412 3554104 ACon1_001706 CCC(C)(NC(=O)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(=O)N)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F07 compound treatment 124000.0 -11800.0 -0.36 122880.0 5910.0 0.15 -0.1492 -0.3772 3615443 ACon1_001707 COc1cc(O)c2c(=O)oc(/C=C/C(=O)O)cc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F08 compound treatment 40920.0 -94800.0 -2.94 41920.0 -75100.0 -1.95 -3.4568 -0.9802 3559796 ACon1_001708 CC(=O)OC1CCC2(C)C(CC[C@@H]3[C@@H]2CCC4(C)C(CCC34O)C5=CC(=O)OC5)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F09 mock treatment 146920.0 11200.0 0.35 117000.0 28.1 0.0 0.245 0.7086 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F10 mock treatment 137880.0 2120.0 0.07 130400.0 13400.0 0.35 0.2931 0.8256 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F11 compound treatment 78800.0 -57000.0 -1.76 80760.0 -36200.0 -0.94 -1.9133 -0.9566 3615449 ACon1_001709 C[C@H](CC/C=C(\C)/C(=O)O)[C@H]1CC[C@@]2(C)C3CC[C@@H]4[C@]5(C[C@@]35CC(O)[C@]12C)CC[C@H](OC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6O)C4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F12 compound treatment 33000.0 -103000.0 -3.18 28640.0 -88300.0 -2.3 -3.8743 -0.9871 3557871 ACon1_001710 OC(=O)[C@]1(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H](OC(=O)/C=C/c3ccc(O)c(O)c3)[C@@H](C1)OC(=O)/C=C/c4ccc(O)c(O)c4)OC(=O)/C=C/c5ccc(O)c(O)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F13 compound treatment 16960.0 -119000.0 -3.68 13760.0 -103000.0 -2.68 -4.4992 -0.9879 3553379 ACon1_001711 CC(=O)OC[C@]1(C)[C@H](CC[C@@]2(C)[C@H]1C[C@H](OC(=O)C)[C@@]3(C)Oc4cc(oc(=O)c4[C@H](O)[C@H]23)c5cccnc5)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F14 compound treatment 78760.0 -57000.0 -1.77 68560.0 -48400.0 -1.26 -2.1383 -0.9862 3615454 ACon1_001712 CC1CCC2C(C)(C)CCCC2(C)C1(O)C/C=C(\CCOC(=O)C)/C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F15 compound treatment 129560.0 -6200.0 -0.19 103160.0 -13800.0 -0.36 -0.3897 -0.9572 3615457 ACon1_001713 CC1CC(=O)C2=C(CCC3(O)C(O)c4c(O)cccc4C(=O)C23)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F16 compound treatment 141840.0 6080.0 0.19 115160.0 -1810.0 -0.05 0.0999 0.5145 3615460 ACon1_001714 OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4c(=O)cc(Oc5ccc(O)cc5)oc4c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F17 mock treatment 136680.0 917.0 0.03 122040.0 5070.0 0.13 0.1132 0.8404 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F18 mock treatment 130560.0 -5200.0 -0.16 127360.0 10400.0 0.27 0.0769 0.2445 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F19 compound treatment 85800.0 -50000.0 -1.55 73480.0 -43500.0 -1.13 -1.8937 -0.988 3559265 ACon1_001715 COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(=C32)C)c4ccoc4)[C@@H]5OC[C@@]6(C)C5[C@]1(C)[C@H](C[C@H]6OC(=O)C)OC(=O)/C(=C/C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F20 compound treatment 130720.0 -5040.0 -0.16 108880.0 -8090.0 -0.21 -0.2591 -0.9893 3615464 ACon1_001716 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H](Cl)[C@@](O)(COC(=O)c4ccccc4)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F21 compound treatment 116400.0 -19400.0 -0.6 95520.0 -21500.0 -0.56 -0.8183 -0.9993 3615468 ACon1_001717 C[C@H](CC/C=C(\C)/C(=O)OC1OC(CO)C(O)C1O)[C@H]2CC(O)[C@@]3(C)C4CC[C@@H]5[C@]6(C[C@@]46CC(O)[C@]23C)CC[C@H](O[C@@H]7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O)C5(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F22 compound treatment 127000.0 -8760.0 -0.27 111480.0 -5490.0 -0.14 -0.2929 -0.9549 3615471 ACon1_001718 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=CC43OC(=O)C(=C4)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F23 compound treatment 91760.0 -44000.0 -1.36 78440.0 -38500.0 -1.0 -1.672 -0.9885 3615473 ACon1_001719 CCCCCCCCC#CC#C/C=C/CCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 F24 compound treatment 24120.0 -112000.0 -3.46 17400.0 -99600.0 -2.59 -4.2754 -0.9898 3615477 ACon1_001720 COc1cc(nc(/C=N/O)c1SC)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G01 compound treatment 82120.0 -53600.0 -1.66 64600.0 -52400.0 -1.36 -2.1375 -0.9951 3615480 ACon1_001721 C/C=C/C#CC#C[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)\C=C\CCCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G02 compound treatment 99120.0 -36600.0 -1.14 82720.0 -34300.0 -0.89 -1.4321 -0.9927 3615484 ACon1_001722 CC1OC(Oc2ccc(cc2)c3cc(=O)c4c(O)cc(OC5OC(CO)C(O)C(O)C5O)cc4o3)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G03 mock treatment 113320.0 -22400.0 -0.7 88680.0 -28300.0 -0.74 -1.0115 -0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G04 mock treatment 129600.0 -6160.0 -0.19 94440.0 -22500.0 -0.59 -0.549 -0.8915 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G05 compound treatment 138960.0 3200.0 0.1 94840.0 -22100.0 -0.58 -0.3366 -0.5768 3552804 ACon1_001723 C[C@@H]1O[C@@H](Oc2ccc(cc2)c3coc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc(O)c4c3=O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G06 compound treatment 89920.0 -45800.0 -1.42 74920.0 -42100.0 -1.09 -1.777 -0.9916 3615487 ACon1_001724 OCC1OC(C(OC(=O)c2cc(O)c(O)c(O)c2)C(OC(=O)c3cc(O)c(O)c(O)c3)C1O)c4c(O)cc(O)c(C(=O)c5ccc(O)cc5)c4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G07 compound treatment 50160.0 -85600.0 -2.65 51640.0 -65300.0 -1.7 -3.0758 -0.9767 3557601 ACon1_001725 CO[C@@H]1[C@H]2OC(=O)[C@@]3(CCCC(C)(C)C23)c4c(O)c(O)c(cc14)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G08 compound treatment 118040.0 -17700.0 -0.55 94040.0 -22900.0 -0.6 -0.8096 -0.9992 3615490 ACon1_001726 CC1(CO)CC[C@@]2(COC34C=CC5[C@@]6(C)CC[C@H](OC7OCC(O)C(O)C7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)CC2O)C3C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G09 compound treatment 104600.0 -31200.0 -0.97 86800.0 -30200.0 -0.78 -1.2371 -0.9947 3559858 ACon1_001727 CCCCC[C@H](O)[C@H](O)/C=C/[C@@H](O)CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G10 compound treatment 125080.0 -10700.0 -0.33 95360.0 -21600.0 -0.56 -0.6311 -0.9682 3615494 ACon1_001728 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](OC(=O)/C=C/c3ccc(O)cc3)[C@H](O)[C@H]2O)[C@H]4[C@@H]1[C@H](O)C[C@]4(C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G11 compound treatment 71520.0 -64200.0 -1.99 65040.0 -51900.0 -1.35 -2.3616 -0.9821 3557471 ACon1_001729 COC(=O)c1cccc2oc3cc(C)cc(O)c3c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G12 compound treatment 80960.0 -54800.0 -1.7 62920.0 -54100.0 -1.4 -2.1938 -0.9956 3615499 ACon1_001730 C[C@H]1CCc2cccnc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)c6ccccc6)[C@@H](O)[C@H](OC1=O)[C@]4(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G13 compound treatment 99280.0 -36500.0 -1.13 64440.0 -52500.0 -1.36 -1.7645 -0.9956 3615503 ACon1_001731 CCCCCCCCCCCCCCCC(=O)CCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G14 compound treatment 112600.0 -23200.0 -0.72 96760.0 -20200.0 -0.53 -0.8788 -0.9882 3557525 ACon1_001732 CC1OC(OC2C(O)C(OCCc3ccc(O)c(O)c3)OC(CO)C2OC(=O)/C=C/c4ccc(O)c(O)c4)C(OC5OCC(O)C(O)C5O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G15 compound treatment 121960.0 -13800.0 -0.43 102120.0 -14900.0 -0.39 -0.5753 -0.9987 3615506 ACon1_001733 Cc1ccc(c(O)c1)C(O)(CO)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G16 compound treatment 122640.0 -13100.0 -0.41 81640.0 -35300.0 -0.92 -0.9366 -0.9329 3615508 ACon1_001734 COc1cc(CCC(O)CC(O)CCc2ccc(O)c(O)c2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G17 compound treatment 104880.0 -30900.0 -0.96 76480.0 -40500.0 -1.05 -1.4206 -0.9989 3615509 ACon1_001735 COc1cccc2C(=O)c3c(C(O)c12)c(SCC(NC(=O)C)C(=O)O)cc4C(O)C(C)CC(=O)c43 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G18 compound treatment 113560.0 -22200.0 -0.69 96160.0 -20800.0 -0.54 -0.8688 -0.9929 3615511 ACon1_001736 CCC(C)C(NC(=O)C(C)(C)NC(=O)C(C)(CC)NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)NC(=O)CCC(NC(=O)C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G19 mock treatment 130280.0 -5480.0 -0.17 124320.0 7350.0 0.19 0.0149 0.0582 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G20 mock treatment 132400.0 -3360.0 -0.1 128160.0 11200.0 0.29 0.1319 0.4271 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G21 compound treatment 141000.0 5240.0 0.16 109560.0 -7410.0 -0.19 -0.0214 -0.0851 2106469 ACon1_001737 COc1ccc2ccc(=O)oc2c1C(O)C(O)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G22 compound treatment 122880.0 -12900.0 -0.4 101280.0 -15700.0 -0.41 -0.5705 -0.9999 3615514 ACon1_001738 COC1=CC(=O)OC1C(O)C(O)C(OC(=O)C)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G23 compound treatment 110640.0 -25100.0 -0.78 103000.0 -14000.0 -0.36 -0.8071 -0.9397 3615516 ACon1_001739 C[C@@H]1O[C@@H](Oc2ccc(cc2O)C3Oc4cc(O)cc(O)c4C(=O)C3O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 G24 compound treatment 5160.0 -131000.0 -4.05 3920.0 -113000.0 -2.94 -4.9385 -0.9876 3559198 ACon1_001740 C[C@H]1[C@@]2(O)[C@H](CC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@@]32C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)O[C@@]91CCC(C)CO9 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H01 compound treatment 21960.0 -114000.0 -3.53 28360.0 -88600.0 -2.3 -4.1214 -0.9787 3615520 ACon1_001741 CC(=O)OC[C@]1(C)[C@@H](CC[C@@]2(C)C3CCC4CC3(CC4(O)CO)CC[C@H]12)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H02 compound treatment 101240.0 -34500.0 -1.07 94400.0 -22600.0 -0.59 -1.1711 -0.96 3615525 ACon1_001742 COC(=O)[C@H](O)[C@H]1C(C)(C)[C@H](OC(=O)C)[C@]2(O)CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H03 mock treatment 154160.0 18400.0 0.57 123840.0 6870.0 0.18 0.5293 0.8861 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H04 mock treatment 144600.0 8840.0 0.27 124720.0 7750.0 0.2 0.336 0.9886 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H05 compound treatment 148800.0 13000.0 0.4 137360.0 20400.0 0.53 0.6602 0.991 3615530 ACon1_001743 COc1c(O)cc2c(=O)oc3c(OC)c(O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)cc5c(=O)oc1c2c53 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H06 compound treatment 64040.0 -71700.0 -2.22 56200.0 -60800.0 -1.58 -2.6879 -0.986 3552916 ACon1_001744 C[C@H](/C=C/C=C(\C)/C(=O)N[C@H]1[C@@H](C)[C@@H](C)OC1=O)[C@H]2CC[C@@]3(C)[C@@H]4CCC5[C@]6(C[C@@]46CC[C@]23C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O[C@@H]9O[C@H](CO[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@@H](O)[C@H](O)[C@H]9O[C@@H]%11O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%11O)C5(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H07 compound treatment 61640.0 -74100.0 -2.3 60080.0 -56900.0 -1.48 -2.6692 -0.9773 2060370 ACon1_001745 COc1cc2OCOc2cc1c3coc4c5C=CC(C)(C)Oc5c(OC)cc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H08 compound treatment 48800.0 -87000.0 -2.69 35920.0 -81100.0 -2.11 -3.3944 -0.9926 3559797 ACon1_001746 CO[C@H]1C[C@H](OC2CCC3(C)[C@@H](CCC4C3CCC5(C)C(CC(OC(=O)C)C45O)C6=CC(=O)OC6)C2)O[C@@H](C)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H09 compound treatment 81360.0 -54400.0 -1.69 70320.0 -46700.0 -1.21 -2.049 -0.9869 3615536 ACon1_001747 CC1OC(O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5[C@@H]6CC(C)(C)C[C@@H](O)[C@]6(C)CC[C@]54C)[C@@]2(C)CO)C(OC7OC(C(O)C(O)C7OC8OCC(O)C(O)C8O)C(=O)O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H10 compound treatment 38960.0 -96800.0 -3.0 35200.0 -81800.0 -2.12 -3.6232 -0.9857 3559799 ACon1_001748 C[C@@H]1O[C@@H](OC2CCC3(C)[C@@H](CCC4C3CCC5(C)C(CCC45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H11 compound treatment 113680.0 -22100.0 -0.68 107640.0 -9330.0 -0.24 -0.6553 -0.9027 3055308 ACon1_001749 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)C[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H12 compound treatment 139920.0 4160.0 0.13 144840.0 27900.0 0.72 0.6031 0.82 3615541 ACon1_001750 CCCC1=CC(=O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H13 compound treatment 161600.0 25800.0 0.8 121960.0 4990.0 0.13 0.6577 0.811 3558466 ACon1_001751 O[C@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H14 compound treatment 142640.0 6880.0 0.21 128040.0 11100.0 0.29 0.354 0.9891 3615544 ACon1_001752 C[C@@H]1C[C@H]2OC(=O)[C@@]3(C)CCC[C@](C)(C23)[C@]41CCC5(COC(O)C5)O4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H15 compound treatment 128280.0 -7480.0 -0.23 113920.0 -3050.0 -0.08 -0.22 -0.8979 3615548 ACon1_001753 COc1ccc(CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(=O)C)c3cc(C)oc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H16 compound treatment 75760.0 -60000.0 -1.86 66000.0 -51000.0 -1.32 -2.2511 -0.9862 3615551 ACon1_001754 COc1cc2C[C@@H]3[C@H](COC3=O)[C@@H](OC(=O)C)c4cc5OCOc5cc4-c2c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H17 compound treatment 105440.0 -30300.0 -0.94 82400.0 -34600.0 -0.9 -1.2995 -0.9997 3615554 ACon1_001755 CC1OC(OCC2OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CCC6=C5CC[C@]7(CCC(C)(C)CC67)C(=O)OC8OC(CO)C(O)C(O)C8O)C3(C)C)C(O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H18 compound treatment 139200.0 3440.0 0.11 101880.0 -15100.0 -0.39 -0.202 -0.497 3615558 ACon1_001756 C[C@@H]1O[C@H]2Oc3c(oc4cc(O)c(c(O)c4c3=O)-c5cc(/C=C/C(=O)OC[C@H]6O[C@@H](O[C@H]([C@H]1O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]6O)ccc5O)c7ccc(O)c(O)c7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H19 mock treatment 150760.0 15000.0 0.46 128480.0 11500.0 0.3 0.54 0.9773 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H20 mock treatment 139400.0 3640.0 0.11 122400.0 5430.0 0.14 0.1794 0.9938 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H21 compound treatment 140160.0 4400.0 0.14 119000.0 2030.0 0.05 0.1336 0.9146 3615562 ACon1_001757 CC1CCC2C(C)(C=O)C(O)CCC2(C)C1CC/C(=C\C(=O)O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H22 compound treatment 115240.0 -20500.0 -0.64 103920.0 -13100.0 -0.34 -0.6894 -0.9567 3558771 ACon1_001758 CC1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C)C(O)C(O)C6O)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H23 compound treatment 55160.0 -80600.0 -2.5 41800.0 -75200.0 -1.95 -3.1471 -0.9926 3615567 ACon1_001759 COc1ccc2c3[C@H](OCC=C(C)C)[C@]4(O)N([C@H]5CC(C)(C)OO[C@H](C=C(C)C)n(c53)c2c1)C(=O)[C@@H]6CCCN6C4=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 H24 compound treatment 71280.0 -64500.0 -2.0 69560.0 -47400.0 -1.23 -2.2839 -0.973 1055133 ACon1_001760 COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I01 compound treatment 15680.0 -120000.0 -3.72 13880.0 -103000.0 -2.68 -4.525 -0.987 3615574 ACon1_001761 CNC1CCC23CC34CCC5(C)C(C(C)N(C)C(=O)C)C(O)CC5(C)C4CCC2C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I02 compound treatment 75480.0 -60300.0 -1.87 60960.0 -56000.0 -1.46 -2.3498 -0.9924 3615576 ACon1_001762 C[C@@H]1O[C@@H](OC(=O)[C@@]23CCC(C)(C)CC3C4=CCC5[C@@]6(C)C[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]2O)[C@@H](O[C@@H]8OC[C@@H](O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O[C@@H]%10OC[C@@H](O)[C@@H](O)[C@@H]%10O)[C@@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I03 compound treatment 43760.0 -92000.0 -2.85 40880.0 -76100.0 -1.98 -3.4137 -0.984 3555361 ACon1_001763 COCC1C(=O)O[C@H]2C[C@@]3(C)OC(=O)/C(=C/C)/[C@]43CC[C@@](C)(O)CC(=O)[C@]12O4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I04 compound treatment 95120.0 -40600.0 -1.26 84080.0 -32900.0 -0.85 -1.4948 -0.9822 3615580 ACon1_001764 CC1(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)CC[C@]2(CC1O)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I05 mock treatment 129120.0 -6640.0 -0.21 107880.0 -9090.0 -0.24 -0.3126 -0.9976 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I06 mock treatment 134240.0 -1520.0 -0.05 100280.0 -16700.0 -0.43 -0.34 -0.7794 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I07 compound treatment 21400.0 -114000.0 -3.54 16800.0 -100000.0 -2.6 -4.346 -0.9885 3615585 ACon1_001765 O[C@@H]1[C@@H](COC(=O)/C=C/c2ccc(O)cc2)O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H]1OC(=O)/C=C/c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I08 compound treatment 124560.0 -11200.0 -0.35 109280.0 -7690.0 -0.2 -0.3868 -0.9656 3615588 ACon1_001766 C[C@H]1[C@H](O)C=CC2=CC(=O)[C@@](O)(C[C@]12C)C(=C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I09 compound treatment 139400.0 3640.0 0.11 104760.0 -12200.0 -0.32 -0.1447 -0.4296 3554244 ACon1_001767 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCC(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I10 compound treatment 67720.0 -68000.0 -2.11 49320.0 -67700.0 -1.76 -2.7337 -0.9959 3615592 ACon1_001768 C[C@H]1CCc2ccncc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)C)[C@@H](O)[C@H](O)[C@]4(C)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I11 compound treatment 32400.0 -103000.0 -3.2 30520.0 -86500.0 -2.25 -3.853 -0.9849 3555007 ACon1_001769 COc1cc(OC)c2c(O)c3C(=O)CC(C)(O)Oc3cc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I12 compound treatment 132400.0 -3360.0 -0.1 102680.0 -14300.0 -0.37 -0.3363 -0.8718 3615597 ACon1_001770 COC1OC(=O)C(CCC2(C)C(C)CCC3(C)C2CC(O)C(O)C43CO4)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I13 compound treatment 120200.0 -15600.0 -0.48 80040.0 -36900.0 -0.96 -1.0195 -0.9493 3615600 ACon1_001771 COc1ccc(OC2OC(COC3OCC(O)C(O)C3O)C(O)C(O)C2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I14 compound treatment 130920.0 -4840.0 -0.15 86160.0 -30800.0 -0.8 -0.6722 -0.8253 3615602 ACon1_001772 COc1cc(O)c-2c(CCc3cc(O)c(OC)cc32)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I15 compound treatment 89480.0 -46300.0 -1.43 67240.0 -49700.0 -1.29 -1.9277 -0.9986 3615604 ACon1_001773 O[C@@H]1[C@@H](Oc2c([C@H]3C[C@@H](Oc4cc(O)ccc34)c5ccc(O)c(O)c5)c(O)cc(O)c2C1=O)c6ccc(O)c(O)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I16 compound treatment 93120.0 -42600.0 -1.32 84440.0 -32500.0 -0.85 -1.532 -0.9767 3615608 ACon1_001774 CC1(C)C2CC[C@]3(C[C@H]4CC[C@H]3[C@@]52CC[C@@]1(O)OC5)CC4(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I17 compound treatment 139840.0 4080.0 0.13 120480.0 3510.0 0.09 0.1538 0.9872 3615612 ACon1_001775 OC[C@H]1O[C@@H](Oc2ccc(C(=O)CCc3ccc(O)cc3)c(O)c2)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I18 compound treatment 114280.0 -21500.0 -0.67 97160.0 -19800.0 -0.51 -0.8347 -0.9919 3558031 ACon1_001776 COc1ccc(/C=C/C(=O)OC2C(C)OC(OC3C4OC4(CO)C5C3C=COC5OC6OC(CO)C(O)C(O)C6O)C(O)C2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I19 compound treatment 29720.0 -106000.0 -3.29 31120.0 -85900.0 -2.23 -3.9006 -0.9822 3554120 ACon1_001777 CCC(C)[C@@H]1N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I20 compound treatment 53120.0 -82600.0 -2.56 37440.0 -79500.0 -2.07 -3.2719 -0.9943 3559162 ACon1_001778 Oc1ccc(cc1)[C@H]2[C@H]([C@@H]3[C@H](c4ccc(O)cc4)c5ccc(O)cc5OC3=O)C(=O)Oc6cc(O)ccc26 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I21 mock treatment 142160.0 6400.0 0.2 131200.0 14200.0 0.37 0.4016 0.9573 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I22 mock treatment 136320.0 557.0 0.02 129200.0 12200.0 0.32 0.2369 0.7444 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I23 compound treatment 144080.0 8320.0 0.26 116320.0 -652.0 -0.02 0.1703 0.6592 3615618 ACon1_001779 COc1cc(CCC(=O)O)oc(=O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 I24 compound treatment 5800.0 -130000.0 -4.03 4680.0 -112000.0 -2.92 -4.9105 -0.9875 3615620 ACon1_001780 CC(C)C(=C)CCC(C)[C@H]1CC=C2C3=C([C@@H](O)[C@H](OC(=O)C)[C@]12C)[C@@]4(C)C[C@@H](O)[C@H](O)C(C)(C)C4CC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J01 compound treatment 119960.0 -15800.0 -0.49 110560.0 -6410.0 -0.17 -0.464 -0.8972 3615624 ACon1_001781 CC(=CCc1c(O)ccc2cc(O)c(=O)oc12)COC3OC(CO)C(O)C(O)C3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J02 compound treatment 115560.0 -20200.0 -0.63 93520.0 -23500.0 -0.61 -0.8735 -0.9999 3615625 ACon1_001782 CC1OC(OC2C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC65C)C(=O)OC8OC(CO)C(OC9OCC(OC%10OCC(O)C(O)C%10O)C(O)C9O)C(O)C8O)C3(C)C)OC(C2O)C(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J03 compound treatment 128200.0 -7560.0 -0.23 103800.0 -13200.0 -0.34 -0.4077 -0.9829 3615627 ACon1_001783 CC1(CO)CC(O)[C@@]2(CCC34CC4(C=CC5[C@@]6(C)C[C@@H](O)[C@H](O)C(CO)(CO)C6CC[C@]53C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J04 compound treatment 16800.0 -119000.0 -3.69 15760.0 -101000.0 -2.63 -4.4659 -0.9863 3558573 ACon1_001784 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](O)C(C)(C)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J05 mock treatment 145160.0 9400.0 0.29 126520.0 9550.0 0.25 0.3813 0.9968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J06 mock treatment 134160.0 -1600.0 -0.05 127440.0 10500.0 0.27 0.1572 0.5686 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J07 compound treatment 107520.0 -28200.0 -0.88 85680.0 -31300.0 -0.81 -1.1937 -0.9993 3615632 ACon1_001785 COc1cc(O)cc(C)c1C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(OC)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J08 compound treatment 39120.0 -96600.0 -2.99 38680.0 -78300.0 -2.03 -3.5558 -0.9823 3559809 ACon1_001786 CO[C@H]1[C@@H](O)[C@@H](C)O[C@@H](OC2CCC3(C)C(CC[C@@H]4[C@@H]3CCC5(C)C(C(O)CC45O)C6=CC(=O)OC6)C2)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J09 compound treatment 78120.0 -57600.0 -1.79 50560.0 -66400.0 -1.73 -2.4831 -0.9999 3557709 ACon1_001787 COc1cc(cc(OC)c1O)C2C(COC3OC(CO)C(O)C(O)C3O)C(CO)Cc4cc(OC)c(O)c(OC)c24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J10 compound treatment 112680.0 -23100.0 -0.72 108360.0 -8610.0 -0.22 -0.6639 -0.886 3559803 ACon1_001788 CC12CC[C@H]3C(CCC4(O)CC(O)CCC34O)C2(O)CCC1C5=CC(=O)OC5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J11 compound treatment 16840.0 -119000.0 -3.68 16160.0 -101000.0 -2.62 -4.4577 -0.986 3559166 ACon1_001789 COc1cc2OCOc2cc1c3coc4c5C=CC(C)(C)Oc5ccc4c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J12 compound treatment 85360.0 -50400.0 -1.56 60520.0 -56500.0 -1.47 -2.1415 -0.9995 3615637 ACon1_001790 O[C@@H]1CO[C@@H](OC(CCc2ccc(O)cc2)CC(=O)CCc3ccc(O)cc3)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J13 compound treatment 113320.0 -22400.0 -0.7 103440.0 -13500.0 -0.35 -0.7403 -0.9501 3557350 ACon1_001791 C[C@@H]1CC(=O)c2c(C1)ccc3C(=O)c4c(O)cccc4C(=O)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J14 compound treatment 12880.0 -123000.0 -3.81 10600.0 -106000.0 -2.76 -4.6466 -0.9876 3615642 ACon1_001792 CC1(CCCC2(C)C3CCC(=C)C(C=C)C3CCC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J15 compound treatment 139520.0 3760.0 0.12 126160.0 9190.0 0.24 0.2511 0.9455 3615644 ACon1_001793 Cc1cc2c(CO)cc(SCC(O)C(=O)O)cc2o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J16 compound treatment 160520.0 24800.0 0.77 119760.0 2790.0 0.07 0.5936 0.7705 3615646 ACon1_001794 OCC1OC(Oc2c(O)cccc2COC(=O)C3(O)C=CCCC3=O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J17 compound treatment 106360.0 -29400.0 -0.91 86320.0 -30700.0 -0.8 -1.2073 -0.9978 3615649 ACon1_001795 OC(CNC(=O)/C=C/c1ccc(O)cc1)c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J18 compound treatment 140280.0 4520.0 0.14 135320.0 18300.0 0.48 0.4361 0.8777 3615653 ACon1_001796 C[C@@H]1O[C@H]2Oc3c(oc4cc(O)c(c(O)c4c3=O)-c5cc(/C=C/C(=O)OC[C@H]6O[C@@H](O[C@H]([C@H]1O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]6O)ccc5O)c7ccc(O)cc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J19 compound treatment 135720.0 -42.6 0.0 123400.0 6430.0 0.17 0.1172 0.7015 3615657 ACon1_001797 COCC1OC(OC(C)(C)C(O)CCC2(C)C/C(=C/3\CCC4C3(C)CC(O)C5OC(CCC45C)C(C)(C)OC6OC(COC)C(O)C(O)C6NC(=O)C)/CCC2O)C(NC(=O)C)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J20 compound treatment 129080.0 -6680.0 -0.21 116960.0 -11.9 0.0 -0.1466 -0.7082 3615662 ACon1_001798 CC1OC(Oc2cc(O)c3c(=O)cc(oc3c2C4OC(CO)C(O)C(O)C4O)c5ccc(O)cc5)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J21 mock treatment 186160.0 50400.0 1.56 136800.0 19800.0 0.52 1.4685 0.893 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J22 mock treatment 128400.0 -7360.0 -0.23 122200.0 5230.0 0.14 -0.0653 -0.2458 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J23 compound treatment 27120.0 -109000.0 -3.37 18880.0 -98100.0 -2.55 -4.1825 -0.9906 3615664 ACon1_001799 CC(C)CC1NC(=O)C(CC(C)C)N(O[C@@H]2O[C@H](COC(=O)CCC(=O)O)[C@@H](O)[C@H](O)[C@H]2O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 J24 compound treatment 68720.0 -67000.0 -2.08 60440.0 -56500.0 -1.47 -2.5075 -0.9856 3615667 ACon1_001800 COc1ccc2nccc(C(O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K01 compound treatment 83280.0 -52500.0 -1.63 67320.0 -49700.0 -1.29 -2.0621 -0.9934 3615669 ACon1_001801 CCN1CC2(COC)CCC(O)C3(C4CC5C(O)C4C(O)(CC5OC)C6C(OC)C32)C61 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K02 compound treatment 96400.0 -39400.0 -1.22 67920.0 -49100.0 -1.27 -1.7636 -0.9998 3615671 ACon1_001802 CC1=CCC(CC1)C(C)(C)O[C@@H]2O[C@H](CO[C@@H]3O[C@H](COC(=O)c4cc(O)c(O)c(O)c4)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K03 compound treatment 116480.0 -19300.0 -0.6 80080.0 -36900.0 -0.96 -1.1003 -0.9741 3558951 ACon1_001803 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6OC[C@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K04 compound treatment 125560.0 -10200.0 -0.32 98320.0 -18700.0 -0.48 -0.5662 -0.9786 3615676 ACon1_001804 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3ccc(CC=C)cc3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K05 compound treatment 105800.0 -30000.0 -0.93 93200.0 -23800.0 -0.62 -1.0932 -0.9804 3555002 ACon1_001805 COc1cc(oc(=O)c1)[C@H](Cc2ccccc2)NC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K06 compound treatment 54440.0 -81300.0 -2.52 46960.0 -70000.0 -1.82 -3.068 -0.9872 3615680 ACon1_001806 C/C(=C/CCC(CO)C1CCC2(C)C3CCC4C5(CC35CCC12C)CCC(OC6OC(CO)C(O)C(O)C6O)C4(C)C)/COC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K07 mock treatment 129480.0 -6280.0 -0.19 99640.0 -17300.0 -0.45 -0.4561 -0.9296 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K08 mock treatment 139680.0 3920.0 0.12 105280.0 -11700.0 -0.3 -0.129 -0.3943 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K09 compound treatment 138320.0 2560.0 0.08 98760.0 -18200.0 -0.47 -0.2786 -0.5806 3553885 ACon1_001807 CC1(CC(=O)O)CCC2(O1)C(=CCC3C(C)(C)C(O)CCC32C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K10 compound treatment 127680.0 -8080.0 -0.25 88840.0 -28100.0 -0.73 -0.6939 -0.8981 3615685 ACon1_001808 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)OC(=O)C)OC(=O)/C=C\c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K11 compound treatment 124120.0 -11600.0 -0.36 92320.0 -24700.0 -0.64 -0.708 -0.9631 3558491 ACon1_001809 COc1cc(ccc1O)[C@H]2OC[C@@H]3[C@H](OC[C@H]23)c4ccc(O)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K12 compound treatment 142160.0 6400.0 0.2 118760.0 1790.0 0.05 0.173 0.8498 3615689 ACon1_001810 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)O)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K13 compound treatment 132800.0 -2960.0 -0.09 102480.0 -14500.0 -0.38 -0.3312 -0.8545 3557476 ACon1_001811 OCC1OC(C(O)C(O)C1O)c2c(O)c(C3OCC(O)C(O)C3O)c4oc(cc(=O)c4c2O)c5ccc(O)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K14 compound treatment 103160.0 -32600.0 -1.01 95320.0 -21700.0 -0.56 -1.1121 -0.9618 3615693 ACon1_001812 OC[C@H]1O[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K15 mock treatment 145400.0 9640.0 0.3 113760.0 -3210.0 -0.08 0.1521 0.4907 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K16 mock treatment 140880.0 5120.0 0.16 106000.0 -11000.0 -0.29 -0.0895 -0.2743 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K17 compound treatment 124000.0 -11800.0 -0.36 100920.0 -16100.0 -0.42 -0.5526 -0.9977 3615697 ACon1_001813 CC(=CCc1cc(CC(N)C(=O)O)ccc1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K18 compound treatment 125920.0 -9840.0 -0.3 90960.0 -26000.0 -0.68 -0.6936 -0.9354 3615699 ACon1_001814 Cc1cc2C(=O)c3cc(O)cc(O)c3C(=O)c2c(O)c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K19 compound treatment 125440.0 -10300.0 -0.32 104000.0 -13000.0 -0.34 -0.4645 -0.9997 1012497 ACon1_001815 NC(Cc1c[nH]c2ccccc12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K20 compound treatment 126000.0 -9760.0 -0.3 112280.0 -4690.0 -0.12 -0.3001 -0.9202 3558198 ACon1_001816 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](OC(=O)/C=C/c6ccc(O)c(O)c6)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K21 compound treatment 96080.0 -39700.0 -1.23 86520.0 -30500.0 -0.79 -1.4289 -0.9773 3615703 ACon1_001817 COC(CCc1ccc(O)c(O)c1)CC(=O)CCc2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K22 compound treatment 113400.0 -22400.0 -0.69 107920.0 -9050.0 -0.24 -0.6563 -0.8969 3615705 ACon1_001818 C/C=C/C=C/C(=O)O[C@@H]1C=C(CO)[C@](O)(CO)[C@@]2(C)CCCC(C)(C)[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K23 mock treatment 126320.0 -9440.0 -0.29 107800.0 -9170.0 -0.24 -0.3754 -0.9948 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 K24 mock treatment 120120.0 -15600.0 -0.48 92880.0 -24100.0 -0.63 -0.7853 -0.992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L01 compound treatment 93080.0 -42700.0 -1.32 75960.0 -41000.0 -1.07 -1.6886 -0.9943 3557532 ACon1_001819 C[C@@H](O)/C=C/[C@@]1(O)C(C)(C)C[C@@H](C[C@@]1(C)O)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L02 compound treatment 130680.0 -5080.0 -0.16 113920.0 -3050.0 -0.08 -0.1674 -0.9496 3615710 ACon1_001820 COc1c(O)c2c(=O)c(O)c(oc2cc1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L03 compound treatment 8440.0 -127000.0 -3.95 8160.0 -109000.0 -2.83 -4.7887 -0.9867 3615714 ACon1_001821 COc1cc(O)c(C(=O)CCc2ccccc2)c(O)c1Cc3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L04 compound treatment 126840.0 -8920.0 -0.28 116240.0 -732.0 -0.02 -0.2089 -0.754 3615716 ACon1_001822 C[C@@]1([C@H](O)CC[C@]2(C)C3CCC(=C)[C@H](C=C)[C@@H]3CC[C@@]12O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L05 compound treatment 127280.0 -8480.0 -0.26 100800.0 -16200.0 -0.42 -0.483 -0.9745 3615720 ACon1_001823 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C3C1C(O)C=C3CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L06 compound treatment 12640.0 -123000.0 -3.81 9400.0 -108000.0 -2.8 -4.6739 -0.9883 3557431 ACon1_001824 CC(C)CCCCCCCCC/C=C/C(=O)NC1C(O)C(O)C(CC(O)C2OC(C(O)C2O)n3ccc(=O)[nH]c3=O)OC1OC4OC(CO)C(O)C(O)C4NC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L07 mock treatment 143520.0 7760.0 0.24 134080.0 17100.0 0.44 0.4843 0.9583 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L08 mock treatment 148160.0 12400.0 0.38 131600.0 14600.0 0.38 0.5404 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L09 compound treatment 138240.0 2480.0 0.08 129920.0 12900.0 0.34 0.2922 0.8467 3615722 ACon1_001825 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(O)C5(C)C(O)(CCC54O)C(=O)C)C2)OC(C)C1OC6CC(OC)C(OC7OC(C)C(O)C(OC)C7O)C(C)O6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L10 compound treatment 45920.0 -89800.0 -2.78 43760.0 -73200.0 -1.9 -3.3135 -0.9828 3559811 ACon1_001826 C[C@H]1O[C@H](C[C@H](OC(=O)C)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)OC4CC(O)C5(C)C(CC[C@@H]6[C@@H]5CCC7(C)C(CCC67O)C8=CC(=O)OC8)C4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L11 compound treatment 140800.0 5040.0 0.16 120920.0 3950.0 0.1 0.1829 0.9793 3615725 ACon1_001827 COC(=O)C(NC(=O)c1cccc(NC=O)c1O)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L12 compound treatment 139480.0 3720.0 0.12 135160.0 18200.0 0.47 0.4156 0.8544 3615727 ACon1_001828 Cc1cc2C(=O)OC(c2c(O)c1)c3c(O)cccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L13 compound treatment 116360.0 -19400.0 -0.6 99000.0 -18000.0 -0.47 -0.7553 -0.9922 3557341 ACon1_001829 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)O[C@@]91CC[C@@](C)(CO)O9 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L14 compound treatment 42560.0 -93200.0 -2.89 28680.0 -88300.0 -2.29 -3.6642 -0.9935 3615729 ACon1_001830 COC1CC(OC2C(C)OC(CC2OC)OC3C(C)OC(CC3OC)OC4C(C)OCC(OC5C(O)C(O[C@H]6CC[C@]7(C)C8CC(OC(=O)c9ccccc9)[C@]%10(C)[C@@](O)(CC[C@]%10(O)[C@]8(O)CC=C7C6)C(=O)C)OC(CO)C5OC%11OC(CO)C(O)C(O)C%11O)C4OC)OC(C)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L15 mock treatment 149080.0 13300.0 0.41 138040.0 21100.0 0.55 0.6789 0.9903 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L16 mock treatment 147920.0 12200.0 0.38 137160.0 20200.0 0.52 0.6373 0.9868 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L17 compound treatment 170000.0 34200.0 1.06 111600.0 -5370.0 -0.14 0.6514 0.6088 3559248 ACon1_001831 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](CO)O[C@H]2OC(=O)[C@@]34CCC(C)(C)C[C@H]4C5=CCC6[C@@]7(C)C[C@H](O)[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@@](C)(CO)C7[C@H](O)C[C@@]6(C)[C@]5(C)C[C@H]3O)[C@H](O)[C@H](O)[C@H]1O[C@@H]9OC[C@@H](O)[C@H](O[C@H]%10OC[C@](O)(CO)[C@H]%10O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L18 compound treatment 128960.0 -6800.0 -0.21 108320.0 -8650.0 -0.22 -0.308 -0.9995 3615734 ACon1_001832 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(COC(=O)c6cc(O)c(O)c(O)c6)C5[C@H](O)C[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L19 compound treatment 139040.0 3280.0 0.1 119560.0 2590.0 0.07 0.1194 0.98 3615738 ACon1_001833 C/C(=C\CC(C)(C)CCC(=O)c1ccoc1)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L20 compound treatment 110880.0 -24900.0 -0.77 98040.0 -18900.0 -0.49 -0.893 -0.9764 3615742 ACon1_001834 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(COC(=O)c5ccccc5)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L21 compound treatment 13360.0 -122000.0 -3.79 14320.0 -103000.0 -2.67 -4.5677 -0.9852 3559153 ACon1_001835 CC/C=C\C[C@H]1[C@@H](CCCCCCCC(=O)O)C=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L22 compound treatment 98200.0 -37600.0 -1.16 81320.0 -35700.0 -0.93 -1.478 -0.9936 3615746 ACon1_001836 Oc1ccc2C3Oc4cc5OCOc5cc4C3COc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L23 mock treatment 138200.0 2440.0 0.08 105040.0 -11900.0 -0.31 -0.1658 -0.5197 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 L24 mock treatment 102520.0 -33200.0 -1.03 84360.0 -32600.0 -0.85 -1.3275 -0.9953 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M01 compound treatment 50160.0 -85600.0 -2.65 43360.0 -73600.0 -1.91 -3.2279 -0.9871 3615749 ACon1_001837 COc1ccc2[nH]c3C4CC/5C(CO)C(Cc3c2c1)N4C\C5=C\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M02 compound treatment 30720.0 -105000.0 -3.25 21400.0 -95600.0 -2.48 -4.0573 -0.9911 3615752 ACon1_001838 C[C@@H]1O[C@@H](OC(=O)[C@@]23CCC(C)(C)CC3C4=CCC5[C@@]6(C)C[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]2O)[C@@H](O[C@@H]8OC[C@@H](O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O[C@@H]%10OC[C@@H](O)[C@H](O)[C@H]%10O)[C@@H]9O)[C@H](O)[C@H]8O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M03 compound treatment 84000.0 -51800.0 -1.6 64600.0 -52400.0 -1.36 -2.0963 -0.9967 3557747 ACon1_001839 C/C(=C\C(=O)O)/CCC1C(C)(O)CCC2C(C)(CO)CCCC12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M04 compound treatment 100560.0 -35200.0 -1.09 83080.0 -33900.0 -0.88 -1.3939 -0.9944 3615755 ACon1_001840 CCC(C)CCC(O)C1CC(CO)OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M05 compound treatment 82800.0 -53000.0 -1.64 73200.0 -43800.0 -1.14 -1.9646 -0.984 3554765 ACon1_001841 COc1c(O)c2c(CCC3C(C)(C)[C@@H]4CC[C@@]32C(=O)O4)cc1C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M06 compound treatment 110400.0 -25400.0 -0.79 81040.0 -35900.0 -0.93 -1.2158 -0.9963 3615758 ACon1_001842 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3C=C(CO)[C@@H]4[C@H]3C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H]2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M07 compound treatment 96960.0 -38800.0 -1.2 91560.0 -25400.0 -0.66 -1.317 -0.9602 812 ACon1_001843 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M08 compound treatment 111720.0 -24000.0 -0.74 84360.0 -32600.0 -0.85 -1.1259 -0.9979 3615763 ACon1_001844 CCCCCC/C=C\[N+](=N[C@@H](COC)[C@H](C)O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M09 mock treatment 134640.0 -1120.0 -0.03 91920.0 -25100.0 -0.65 -0.4849 -0.7438 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M10 mock treatment 133160.0 -2600.0 -0.08 115600.0 -1370.0 -0.04 -0.0822 -0.9326 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M11 compound treatment 113000.0 -22800.0 -0.71 92280.0 -24700.0 -0.64 -0.9524 -0.9989 3615766 ACon1_001845 CCC/C=C/C=C/C1CC(O)C(O)C1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M12 compound treatment 124880.0 -10900.0 -0.34 95960.0 -21000.0 -0.55 -0.6245 -0.9732 3615770 ACon1_001846 CC1CC(=O)CC(C)(C)C1(O)/C=C/C(CO)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M13 mock treatment 146280.0 10500.0 0.33 100800.0 -16200.0 -0.42 -0.0667 -0.1254 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M14 mock treatment 137480.0 1720.0 0.05 104800.0 -12200.0 -0.32 -0.186 -0.58 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M15 compound treatment 88880.0 -46900.0 -1.45 61480.0 -55500.0 -1.44 -2.0467 -1.0 3615774 ACon1_001847 OC1Cc2c(OC1c3ccc(O)c(O)c3)cc(O)c4C(CC(Oc24)c5ccc(O)c(O)c5)c6ccc(O)c(O)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M16 compound treatment 87120.0 -48600.0 -1.51 65680.0 -51300.0 -1.33 -2.0081 -0.9981 3615776 ACon1_001848 COc1cc(CCC(O)CC(=O)CCc2ccc(O)cc2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M17 compound treatment 140280.0 4520.0 0.14 102600.0 -14400.0 -0.37 -0.1651 -0.4139 3615778 ACon1_001849 COc1c(O)c(C(=O)CCc2ccccc2)c(OC)c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M18 compound treatment 70280.0 -65500.0 -2.03 57960.0 -59000.0 -1.53 -2.5189 -0.9905 3615780 ACon1_001850 CC1(C)CC2C3=CCC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6O)C(C)(C)C5CCC4(C)C3(C)CC(O)C2(CC1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M19 compound treatment 87480.0 -48300.0 -1.5 82760.0 -34200.0 -0.89 -1.6864 -0.9691 3615782 ACon1_001851 CC(C)(C=C)[C@]12C[C@@H]3N([C@@H]2Nc4ccccc41)C(=O)c5ccccc5NC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M20 compound treatment 133440.0 -2320.0 -0.07 117960.0 988.0 0.03 -0.0327 -0.4284 3615785 ACon1_001852 CC1=CC2OC3[C@H](O)C[C@@](C)([C@@]43CO4)[C@@]2(CO)CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M21 compound treatment 97520.0 -38200.0 -1.18 92400.0 -24600.0 -0.64 -1.2893 -0.9579 3615790 ACon1_001853 CC1C[C@]2(CC3C(C)(C)[C@@]4(C[C@]53CN2C1=O)C(=O)Nc6c4ccc7OC(C)(C)CC(=O)c67)C(=O)N5C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M22 compound treatment 39960.0 -95800.0 -2.97 30920.0 -86100.0 -2.24 -3.68 -0.9902 3557357 ACon1_001854 CC(C)[C@@H](OC(=O)C)c1nc2ccccc2c(=O)n1[C@@H]3C[C@]4(OC3=O)[C@H]5N(O)[C@@H](C)C(=O)N5c6ccccc64 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M23 compound treatment 139320.0 3560.0 0.11 94520.0 -22500.0 -0.58 -0.3346 -0.5635 3559013 ACon1_001855 Oc1ccc(cc1)[C@@H]2Oc3cc(O)cc(O)c3C(=O)[C@H]2c4c(O)cc(O)c5c(=O)cc(oc45)c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 M24 compound treatment 77560.0 -58200.0 -1.8 80400.0 -36600.0 -0.95 -1.9471 -0.9552 3559205 ACon1_001856 COc1cc(cc(OC)c1OC)[C@H]2OC[C@@H]3[C@@H](OC[C@H]23)c4cc(OC)c(OC)c(OC)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N01 compound treatment 82120.0 -53600.0 -1.66 83360.0 -33600.0 -0.87 -1.7928 -0.9549 3615795 ACon1_001857 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(O)C5(C)C(O)(CCC54O)C(C)O)C2)OC(C)C1OC6CC(OC)C(OC7OC(C)C(O)C(OC)C7O)C(C)O6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N02 compound treatment 116160.0 -19600.0 -0.61 108080.0 -8890.0 -0.23 -0.5928 -0.9123 3615797 ACon1_001858 C[C@@H]1OC(=O)[C@]2(C(=C)[C@@]3(C)OC(=O)[C@@]12O)C4(C)CC[C@]5(C=CC(=O)OC5(C)C)C(=C4[C@H]3OC(=O)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N03 compound treatment 129080.0 -6680.0 -0.21 135440.0 18500.0 0.48 0.1929 0.3691 3615800 ACon1_001859 C/C=C/C1C2OC3=C(C(=O)OC3(C)O)C(=O)C1(C)C4CC(O)C(C)CC4C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N04 compound treatment 141320.0 5560.0 0.17 128400.0 11400.0 0.3 0.3317 0.9664 3615805 ACon1_001860 COc1cc(ccc1O)[C@@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)Oc3ccc(/C=C/CO)cc3OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N05 compound treatment 11960.0 -124000.0 -3.84 10920.0 -106000.0 -2.76 -4.6609 -0.9868 3615808 ACon1_001861 C/C(=C\Cc1c(O)ccc2ccc(=O)oc12)/CO[C@@H]3O[C@H](COC(=O)CC(=O)OC[C@H]4O[C@@H](OC(C)(C)C5Cc6cc7cc(O)c(=O)oc7cc6O5)[C@H](O)[C@@H](O)[C@@H]4O)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N06 compound treatment 114120.0 -21600.0 -0.67 96120.0 -20900.0 -0.54 -0.8573 -0.9944 3557396 ACon1_001862 COC(=O)c1cc(C)cc(OC)c1C2=C(O)C(=O)c3c(O)cccc3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N07 compound treatment 123000.0 -12800.0 -0.4 112840.0 -4130.0 -0.11 -0.3555 -0.8677 3615812 ACon1_001863 COc1cc-2c(CCc3cc(O)c(O)cc32)c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N08 compound treatment 171720.0 36000.0 1.11 175000.0 58000.0 1.51 1.8539 0.9889 3557452 ACon1_001864 C[C@@]12CCC3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CC[C@]1(O)C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N09 mock treatment 144920.0 9160.0 0.28 142320.0 25300.0 0.66 0.6663 0.9292 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N10 mock treatment 130680.0 -5080.0 -0.16 140440.0 23500.0 0.61 0.3198 0.5078 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N11 compound treatment 96000.0 -39800.0 -1.23 114320.0 -2650.0 -0.07 -0.9199 -0.7455 3615814 ACon1_001865 CC1CC(=O)C2=C(CCC34OC42C(=O)c5cccc(O)c5C3O)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N12 compound treatment 153840.0 18100.0 0.56 135760.0 18800.0 0.49 0.7413 0.9977 3554299 ACon1_001866 CCCCCCCCCC[C@H](C(=O)O)[C@@](O)(CCC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N13 mock treatment 140200.0 4440.0 0.14 144160.0 27200.0 0.71 0.5967 0.8292 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N14 mock treatment 146000.0 10200.0 0.32 146720.0 29700.0 0.77 0.7708 0.9226 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N15 compound treatment 152360.0 16600.0 0.51 113280.0 -3690.0 -0.1 0.2958 0.5655 2121 ACon1_001867 Oc1ccc(cc1)c2oc3cc(O)cc(O)c3c(=O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N16 compound treatment 133480.0 -2280.0 -0.07 107840.0 -9130.0 -0.24 -0.2178 -0.8796 3615816 ACon1_001868 CC(C1CC(O)C(C)(C)O1)C2CC[C@@]3(C)C4CC[C@H]5C(C)C(CC[C@]65C[C@@]46CC[C@]23C)OC7OC(COC(=O)C)C(OC8OC(CO)C(OC9OC(CO)C(O)C(O)C9O)C(OC%10OC(C)C(O)C(O)C%10O)C8O)C(OC(=O)C)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N17 compound treatment 153360.0 17600.0 0.55 136280.0 19300.0 0.5 0.7403 0.9991 3615822 ACon1_001869 CC12CC(OC(=O)C2CCC3(C)C1C4OC(=O)C3(O)C5OC54)c6ccoc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N18 compound treatment 142440.0 6680.0 0.21 122760.0 5790.0 0.15 0.2526 0.9877 3615824 ACon1_001870 C/C(=C\Cc1c(O)cc2oc(C)cc(=O)c2c1O)/CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N19 compound treatment 133280.0 -2480.0 -0.08 133040.0 16100.0 0.42 0.2408 0.5673 3615829 ACon1_001871 COCC1OC(OC(C)(C)C2CCC3(C)C4CC/C(=C\5/CCC(O)C(C)(CCC(O)C(C)(C)O)C5)/C4(C)CC(O)C3O2)C(NC(=O)C)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N20 compound treatment 125560.0 -10200.0 -0.32 129040.0 12100.0 0.31 -0.0018 -0.0041 3615833 ACon1_001872 CCCCCC1CC(CC(=O)O1)OC2OC(CO)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N21 compound treatment 94360.0 -41400.0 -1.28 78360.0 -38600.0 -1.0 -1.6165 -0.9926 3554654 ACon1_001873 COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(=C32)C)c4ccoc4)[C@H](O)C5[C@@](C)(C=CC(=O)[C@]15C)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N22 compound treatment 158960.0 23200.0 0.72 103400.0 -13600.0 -0.35 0.2589 0.3234 3558591 ACon1_001874 CC(=CCC[C@@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)C=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N23 compound treatment 139400.0 3640.0 0.11 88680.0 -28300.0 -0.74 -0.4401 -0.5918 3615837 ACon1_001875 C[C@@H]1CCC2C(C)(C)[C@@H](CC[C@]2(C)[C@]31Cc4c(O3)c5CNC(=O)c5cc4O)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 N24 compound treatment 75240.0 -60500.0 -1.88 67000.0 -50000.0 -1.3 -2.2441 -0.9839 3615844 ACon1_001876 COC(=O)C12C(O)C34CC2N5C/C(=C/C)/C1CC5C4N(C)c6ccccc63 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O01 compound treatment 56720.0 -79000.0 -2.45 47360.0 -69600.0 -1.81 -3.0107 -0.9889 3615850 ACon1_001877 COc1cc2CCNC3Cc4ccccc4-c(c1OC)c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O02 compound treatment 46120.0 -89600.0 -2.78 32960.0 -84000.0 -2.18 -3.5075 -0.9929 3615852 ACon1_001878 C[C@@H]1O[C@@H](OC2C(O)C(O)C(CO)OC2O[C@@H]3[C@@H](O)[C@H](O)[C@H](O[C@H]3O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7C8CC(C)(C)C(O)C(O)[C@]8(C)CC[C@]76C)C4(C)C)C(=O)O)[C@H](O)[C@H](O)[C@H]1OC9OCC(O)C(O)C9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O03 compound treatment 96680.0 -39100.0 -1.21 84920.0 -32100.0 -0.83 -1.4452 -0.9833 3552644 ACon1_001879 C[C@@H]1C[C@]2(O[C@H](O)[C@@]3(C)O[C@H]32)O[C@H]4C[C@@]5(C)[C@@H]6CC[C@@H]7[C@]8(C[C@@]68C[C@@H](OC(=O)C)[C@]5(C)[C@H]41)CC[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)C7(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O04 compound treatment 65800.0 -70000.0 -2.17 63240.0 -53700.0 -1.4 -2.52 -0.9774 3615859 ACon1_001880 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O05 compound treatment 81600.0 -54200.0 -1.68 60640.0 -56300.0 -1.46 -2.2216 -0.9977 3558011 ACon1_001881 CC(=O)OC[C@]1(C)CC2[C@]3(CO[C@]42CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]3OC%10OCC(OC%11OC(CO)C(O)C(O)C%11O)C(O)C%10O)[C@@H](O)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O06 compound treatment 126080.0 -9680.0 -0.3 96360.0 -20600.0 -0.54 -0.5908 -0.9625 3615865 ACon1_001882 CC1C2CC3(CC(O)C4C(C)(CCCC4(C)C3(O)CC2)C(=O)OC5OC(CO)C(O)C(O)C5O)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O07 compound treatment 117280.0 -18500.0 -0.57 104800.0 -12200.0 -0.32 -0.6286 -0.9608 3554487 ACon1_001883 CN1C(Cc2ccccc2)C(=O)Nc3ccccc3C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O08 compound treatment 141800.0 6040.0 0.19 122360.0 5390.0 0.14 0.2313 0.9898 3615867 ACon1_001884 CC(=O)O[C@@H]1C[C@@]2(CO2)[C@](O)(CCc3ccoc3)[C@]4(CCC[C@@]5(C)C14)COC5=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O09 compound treatment 126320.0 -9440.0 -0.29 106000.0 -11000.0 -0.29 -0.4085 -0.9999 3615872 ACon1_001885 COC(=O)c1cccc(OC(C)C(=O)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O10 compound treatment 62600.0 -73200.0 -2.27 62000.0 -55000.0 -1.43 -2.6129 -0.9752 3615878 ACon1_001886 CC1C(C)c2cccnc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)C)[C@@H](O)[C@H](OC1=O)[C@]4(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O11 mock treatment 131400.0 -4360.0 -0.14 127720.0 10700.0 0.28 0.1019 0.3284 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O12 mock treatment 142160.0 6400.0 0.2 133360.0 16400.0 0.43 0.4413 0.9395 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O13 compound treatment 12000.0 -124000.0 -3.83 12400.0 -105000.0 -2.72 -4.6328 -0.9858 3615884 ACon1_001887 CCCCCc1cc(OC)c(CC=C(C)C)c(O)c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O14 compound treatment 134320.0 -1440.0 -0.04 128440.0 11500.0 0.3 0.1791 0.5944 3615887 ACon1_001888 CC(C)(O)C(O)Cc1cc(O)ccc1OC2OC(CO)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O15 compound treatment 142840.0 7080.0 0.22 118120.0 1150.0 0.03 0.1762 0.796 3558264 ACon1_001889 O[C@@H]1C[C@](C[C@@H](O)[C@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)(OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O16 compound treatment 132480.0 -3280.0 -0.1 98080.0 -18900.0 -0.49 -0.419 -0.8359 3615891 ACon1_001890 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)C1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O17 compound treatment 173080.0 37300.0 1.16 160400.0 43400.0 1.13 1.6155 0.9999 3615895 ACon1_001891 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O[C@@H]3OC[C@](O)(CO)[C@H]3O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O18 compound treatment 131240.0 -4520.0 -0.14 127480.0 10500.0 0.27 0.094 0.3062 3615900 ACon1_001892 COC(=O)c1cc2cc(O)c(c(O)c2c(=O)o1)c3c(O)cc4cc(oc(=O)c4c3O)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O19 compound treatment 154120.0 18400.0 0.57 142760.0 25800.0 0.67 0.876 0.9967 3615903 ACon1_001893 CC(=O)NC(CSC(CO)CCCCCCCCCC(=O)O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O20 compound treatment 62560.0 -73200.0 -2.27 49560.0 -67400.0 -1.75 -2.8424 -0.9918 3559173 ACon1_001894 COc1cc(OC)c(cc1OC)C(O)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O21 compound treatment 42920.0 -92800.0 -2.88 32720.0 -84300.0 -2.19 -3.582 -0.9909 3615908 ACon1_001895 Cn/1c(=O)\c(=C\c2ccccc2)\n(C)c(=O)\c1=C\c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O22 compound treatment 131560.0 -4200.0 -0.13 109440.0 -7530.0 -0.2 -0.2305 -0.9804 3559164 ACon1_001896 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@@H](OCCc3ccc(O)c(O)c3)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O23 compound treatment 134840.0 -923.0 -0.03 124440.0 7470.0 0.19 0.117 0.5965 3615916 ACon1_001897 CCC/C=C/C=C/C1CC(O)C(O)C(O)C1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 O24 compound treatment 9640.0 -126000.0 -3.91 7520.0 -109000.0 -2.84 -4.7742 -0.9878 3557540 ACon1_001898 COc1cc(O[C@@H]2O[C@H](CO[C@H]3OC[C@](O)(CO)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P01 compound treatment 18360.0 -117000.0 -3.64 11640.0 -105000.0 -2.74 -4.5074 -0.9902 3615923 ACon1_001899 C[C@H](CC/C=C(\C)/C(=O)OC1OC(CO)C(O)C(O)C1O)[C@H]2CC(O)[C@@]3(C)C4CC[C@@H]5[C@]6(C[C@@]46CC(O)[C@]23C)CC[C@H](O[C@@H]7OC(COC8OCC(O)C(O)C8O)C(O)C(O)C7O)C5(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P02 compound treatment 13960.0 -122000.0 -3.77 9600.0 -107000.0 -2.79 -4.6413 -0.9889 3615928 ACon1_001900 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]8O[C@H](CO)[C@H](O)[C@H](O)[C@H]8O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P03 compound treatment 25280.0 -110000.0 -3.42 19200.0 -97800.0 -2.54 -4.2169 -0.9892 3615934 ACon1_001901 CC1(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(=O)O)[C@](C)(CO)C5CC[C@@]4(C)C3(C)CC[C@@]2(C)[C@H](OC8OCC(O)C(OC9OC(CO)C(O)C(O)C9O)C8O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P04 compound treatment 4840.0 -131000.0 -4.06 4360.0 -113000.0 -2.93 -4.9374 -0.9871 3615941 ACon1_001902 CCC(C)CCCCCCCCC1CC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P05 compound treatment 86640.0 -49100.0 -1.52 74640.0 -42300.0 -1.1 -1.854 -0.9873 3615944 ACon1_001903 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(OC%10OC(CO)C(O)C(O)C%10O)C(O)C9O)C(OC)C8O)C(C)O7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P06 compound treatment 7680.0 -128000.0 -3.97 7480.0 -109000.0 -2.84 -4.8179 -0.9867 3553131 ACon1_001904 C[C@H]1CC[C@@H]2[C@H]([C@@H](C)C=C[C@H]2C1)C(=O)c3c(O)c(cn(O)c3=O)[C@]4(O)CC[C@@H](O)[C@H]5O[C@H]54 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P07 compound treatment 33200.0 -103000.0 -3.18 31680.0 -85300.0 -2.22 -3.8141 -0.9845 3615949 ACon1_001905 COC1OC(OC)C(O)(CC[C@@]2(O)[C@H](C)C[C@@H](O)C3[C@@](C)(CO)CCC[C@]32C)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P08 compound treatment 142120.0 6360.0 0.2 138880.0 21900.0 0.57 0.5418 0.8995 3557451 ACon1_001906 C[C@@]12C[C@H](O)C3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CC[C@@H]1C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P09 compound treatment 8160.0 -128000.0 -3.95 7920.0 -109000.0 -2.83 -4.7993 -0.9867 3615955 ACon1_001907 CC(=CCc1c(O)c(CC=C(C)C)c2OC(CC(=O)c2c1O)c3ccc(O)cc3O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P10 compound treatment 124640.0 -11100.0 -0.34 137080.0 20100.0 0.52 0.1258 0.2009 3559822 ACon1_001908 CC1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(C)CCC6(CCC54C)C(=O)OC7OC(CO)C(OC8OCC(OC9OC(CO)C(O)C(O)C9O)C(OC%10OCC(O)C(O)C%10O)C8O)C(O)C7O)C2(C)C)C(O)C(O)C1OC%11OCC(O)C(O)C%11O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P11 mock treatment 140560.0 4800.0 0.15 144240.0 27300.0 0.71 0.6061 0.8372 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P12 mock treatment 145560.0 9800.0 0.3 147040.0 30100.0 0.78 0.7671 0.9152 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P13 compound treatment 30240.0 -106000.0 -3.27 26440.0 -90500.0 -2.35 -3.9752 -0.9869 3615961 ACon1_001909 COc1ccc(cc1O)C(C)C(=O)c2ccc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P14 compound treatment 59960.0 -75800.0 -2.35 51480.0 -65500.0 -1.7 -2.864 -0.9875 3615963 ACon1_001910 OCC(=C)C(=O)O[C@H]1C[C@]23O[C@@H]3CC/C(=C/[C@H]4OC(=O)C(=C)[C@@H]41)/CO[C@@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P15 compound treatment 81360.0 -54400.0 -1.69 67920.0 -49100.0 -1.27 -2.0931 -0.9905 3559257 ACon1_001911 OC1(OCC2C(OCC21O)c3ccc4OCOc4c3)c5ccc6OCOc6c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P16 compound treatment 94000.0 -41800.0 -1.29 67840.0 -49100.0 -1.28 -1.8177 -1.0 3615970 ACon1_001912 CC1(C)C(CCC2(C)C3CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C=C)C=C3CCC12)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P17 compound treatment 59920.0 -75800.0 -2.35 46600.0 -70400.0 -1.83 -2.9546 -0.9923 2116652 ACon1_001913 Oc1ccc(CCNC(=O)/C=C/c2ccc(O)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P18 compound treatment 116120.0 -19600.0 -0.61 119040.0 2070.0 0.05 -0.3924 -0.6422 3615976 ACon1_001914 CC1OC(CC(O)C1O)c2cc3oc(cc(=O)c3c(O)c2O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P19 compound treatment 102800.0 -33000.0 -1.02 93320.0 -23700.0 -0.61 -1.1567 -0.9704 3615980 ACon1_001915 CCC(C)C(OC1OC(C)C(O)C(O)C1O)C(C)C(=O)C(C)/C=C(\C)/CC(C)C(O)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P20 compound treatment 61960.0 -73800.0 -2.29 55200.0 -61800.0 -1.61 -2.7519 -0.985 3615986 ACon1_001916 C[C@@H]1O[C@@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](C)O[C@H]2O[C@H]3[C@H](O)[C@@H](NC(=O)C)[C@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC=C7[C@@H]8CC(C)(C)CC[C@@]8(C(O)C[C@]76C)C(=O)OC9OCC(O)C(O)C9O)C4(C)C)O[C@@H]3COC%10OCC(O)C(OC%11OCC(O)C(O)C%11O)C%10O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P21 compound treatment 122600.0 -13200.0 -0.41 102160.0 -14800.0 -0.38 -0.5605 -0.9996 3615991 ACon1_001917 C/C=C/c1ccc(O)cc1C(=O)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P22 compound treatment 115840.0 -19900.0 -0.62 98160.0 -18800.0 -0.49 -0.7821 -0.9933 3615996 ACon1_001918 CC1=C2CC(CCC2(C)CCC1=O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P23 compound treatment 58640.0 -77100.0 -2.39 57480.0 -59500.0 -1.55 -2.7827 -0.9778 3559104 ACon1_001919 COC(=O)[C@H](O)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CC[C@@H](C3=C)[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2295 P24 compound treatment 59680.0 -76100.0 -2.36 54360.0 -62600.0 -1.63 -2.8173 -0.9836 3558533 ACon1_001920 OC[C@H]1O[C@@H](OC2OC=C3[C@@H](C[C@H]4N(CCc5c4[nH]c6ccccc56)C3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A01 compound treatment 78920.0 -55200.0 -1.71 91680.0 -43700.0 -1.14 -2.013 -0.9802 3616000 ACon1_001921 COC(=O)C12CC3CC(C(C)O)C2N(C3)CCc4c1[nH]c5cc(OC)ccc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A02 compound treatment 159640.0 25500.0 0.79 151760.0 16400.0 0.42 0.8594 0.9577 3616002 ACon1_001922 C/C(=C\CC(C)(C)\C=C\Cc1ccoc1)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A03 compound treatment 153600.0 19500.0 0.6 113360.0 -22000.0 -0.57 0.0215 0.0259 3553562 ACon1_001923 CC(C)C1C(O)C2C(CCC(=O)C)C2(C)CC1OC(=O)/C=C/c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A04 compound treatment 174000.0 39900.0 1.24 122280.0 -13100.0 -0.34 0.6324 0.4935 3616008 ACon1_001924 C[C@@H]1CCOC(=O)/C=C/C=C\C(=O)O[C@@H]2C[C@H]3O[C@@H]4C=C(CO)CC[C@]4(COC(=O)[C@H]1O)[C@]2(C)[C@@]53CO5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A05 compound treatment 142040.0 7910.0 0.25 103920.0 -31500.0 -0.82 -0.4052 -0.4745 3554100 ACon1_001925 CCC(=O)OC1C(C)CC2(OC(=O)C)C1C(OC(=O)C)C3(CO3)CCC4C(/C=C(\C)/C2=O)C4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A06 compound treatment 202600.0 68500.0 2.12 154240.0 18800.0 0.49 1.8462 0.848 3616012 ACon1_001926 COc1c(C2OCC(O)C(O)C2O)c(O)cc3oc(cc(=O)c13)c4ccc(OC5OC(C)C(O)C(O)C5O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A07 compound treatment 11200.0 -123000.0 -3.81 6800.0 -129000.0 -3.34 -5.0561 -0.9979 3616015 ACon1_001927 CCC/C=C/C(=O)O[C@H]1CC(C)(C)CC2[C@]34CCC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@@H]([C@@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@H](O)[C@H](O)[C@H]8O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O[C@@H]%10OC[C@](O)(CO)[C@H]%10O)[C@H]7O[C@@H]%11O[C@H](CO)[C@H](O)[C@H](O)[C@H]%11O)C(=O)O)C(C)(C)C6CC[C@@]5(C)[C@]4(C)C[C@@H](OC(=O)C)[C@]21[C@H](O)O3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A08 compound treatment 179840.0 45700.0 1.42 106760.0 -28600.0 -0.74 0.4752 0.297 3616020 ACon1_001928 C[C@@H]1O[C@@H](Oc2cc(O)c3c(=O)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5OC[C@@H](O)[C@H](O)[C@H]5O)[C@H]4O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c(oc3c2)c7ccc(O)cc7)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A09 compound treatment 126120.0 -8010.0 -0.25 34400.0 -101000.0 -2.62 -2.0312 -0.7706 3616025 ACon1_001929 CC1CC(=O)C2C34OC4(C(O)CC2(O)C1)C(O)c5c(O)cccc5C3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A10 compound treatment 149680.0 15500.0 0.48 82080.0 -53300.0 -1.39 -0.639 -0.4357 3558789 ACon1_001930 OCC1OC(OC2C(O)C(O)C(CO)OC2OC3C(O)C(O)C(CO)OC3Oc4c(oc5cc(O)cc(O)c5c4=O)c6ccc(O)c(O)c6)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A11 compound treatment 120040.0 -14100.0 -0.44 78200.0 -57200.0 -1.49 -1.3597 -0.8777 3616030 ACon1_001931 OCC1OC(C(O)C(O)C1OC2OCC(O)(CO)C2O)c3c(O)cc4OC(C(C(=O)c4c3O)c5c(oc6cc(O)cc(O)c6c5=O)c7ccc(O)cc7)c8ccc(O)cc8 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A12 compound treatment 206280.0 72100.0 2.24 137480.0 2080.0 0.05 1.6189 0.724 3616033 ACon1_001932 OCC1OC(C(O)C(O)C1O)c2c(O)cc3occc(=O)c3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A13 mock treatment 209560.0 75400.0 2.34 176840.0 41400.0 1.08 2.4139 0.9381 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A14 mock treatment 213600.0 79500.0 2.46 142800.0 7400.0 0.19 1.877 0.76 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A15 compound treatment 176760.0 42600.0 1.32 141080.0 5680.0 0.15 1.0382 0.7812 3616036 ACon1_001933 OC[C@H]1O[C@@H](Oc2ccc3c(=O)cc(oc3c2)c4ccc(O)cc4)[C@H](O[C@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A16 compound treatment 177280.0 43100.0 1.34 130720.0 -4680.0 -0.12 0.8593 0.6401 3616041 ACon1_001934 CCN1C[C@]2(C)CC[C@H](OC)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@](O)(C[C@@H]5OC)[C@]6(O)[C@@H](OC)C32)[C@H]16 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A17 compound treatment 9560.0 -125000.0 -3.86 6120.0 -129000.0 -3.36 -5.1046 -0.9976 3616047 ACon1_001935 C/C=C(/C)\C(=O)O[C@H]1CC(C)(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]6O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)C[C@@H](O)[C@@]12CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A18 compound treatment 34440.0 -99700.0 -3.09 13800.0 -122000.0 -3.16 -4.4184 -0.9999 3552637 ACon1_001936 C[C@@H]1C[C@@H]2O[C@H]2/C=C\C=C\C(=O)Cc3c(Cl)c(O)cc(O)c3C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A19 compound treatment 9520.0 -125000.0 -3.86 9040.0 -126000.0 -3.28 -5.0518 -0.9967 3616054 ACon1_001937 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4OC(=O)C)c2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A20 compound treatment 189040.0 54900.0 1.7 153920.0 18500.0 0.48 1.5432 0.8728 3559850 ACon1_001938 OC[C@H]1O[C@@H](OC(=O)/C=C/c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A21 compound treatment 104720.0 -29400.0 -0.91 90960.0 -44400.0 -1.15 -1.4609 -0.9931 599 ACon1_001939 Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A22 compound treatment 147640.0 13500.0 0.42 156160.0 20800.0 0.54 0.6773 0.9921 3554279 ACon1_001940 CCCCCCC(C(=O)O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A23 compound treatment 149120.0 15000.0 0.46 139160.0 3760.0 0.1 0.3974 0.8374 3616064 ACon1_001941 COc1cc(oc(=O)c1C)/C(=C/C(C)(O)C(C)O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 A24 compound treatment 103040.0 -31100.0 -0.96 99600.0 -35800.0 -0.93 -1.339 -0.9998 1099693 ACon1_001942 CC(C)(O)C(O)COc1c2occc2cc3ccc(=O)oc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B01 compound treatment 9320.0 -125000.0 -3.87 8000.0 -127000.0 -3.31 -5.0753 -0.997 3498385 ACon1_001943 COC(=O)C1C(O)C=Cc2oc3cc(CO)cc(O)c3c(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B02 compound treatment 178560.0 44400.0 1.38 164120.0 28700.0 0.75 1.501 0.9586 3554822 ACon1_001944 COc1cc(=O)oc(C(C)C(C)O)c1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B03 compound treatment 179920.0 45800.0 1.42 161440.0 26000.0 0.68 1.4815 0.9426 3616073 ACon1_001945 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)C2[C@]1(C)O)C(=O)OC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B04 compound treatment 173440.0 39300.0 1.22 170320.0 34900.0 0.91 1.5027 0.9895 3559763 ACon1_001946 OC[C@H]1O[C@H](S/C(=N/OS(=O)(=O)O)/Cc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B05 compound treatment 167720.0 33600.0 1.04 157000.0 21600.0 0.56 1.1327 0.958 3616080 ACon1_001947 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)C)[C@H](OC(=O)/C=C/c6ccccc6)[C@H]1OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B06 compound treatment 149080.0 14900.0 0.46 120800.0 -14600.0 -0.38 0.0592 0.0989 3553933 ACon1_001948 CC1=CC(=O)C2=C(C)CCC3[C@H](OC(=O)C3=C)[C@@]12O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B07 compound treatment 163160.0 29000.0 0.9 89280.0 -46100.0 -1.2 -0.2114 -0.1411 3616087 ACon1_001949 COC1CC(OC2CCC3(C)C(CCC4(O)C3CC(OC(=O)c5ccccc5)C6(C)C(O)(CCC64O)C(=O)C)C2)OC(C)C1OC7CC(OC)C(OC8OC(C)C(O)C(OC)C8O)C(C)O7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B08 compound treatment 191160.0 57000.0 1.77 112040.0 -23400.0 -0.61 0.8202 0.439 3553383 ACon1_001950 CC(=O)OC[C@H]1O[C@@H](Oc2ccccc2COC(=O)C3(O)C=CCCC3=O)[C@H](OC(=O)C)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B09 compound treatment 184640.0 50500.0 1.56 124920.0 -10500.0 -0.27 0.914 0.5754 3554520 ACon1_001951 CO[C@H]1C(O[C@@H]2C[C@H]3O[C@@H]([C@@H](O)[C@H](O)[C@]3(O)O[C@H]12)C(=O)OC)n4cnc5c(N)ncnc45 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B10 compound treatment 170480.0 36300.0 1.13 133120.0 -2280.0 -0.06 0.7544 0.6689 1011613 ACon1_001952 Oc1cc(=O)oc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B11 compound treatment 13320.0 -121000.0 -3.74 10440.0 -125000.0 -3.25 -4.9428 -0.9975 2095401 ACon1_001953 CC(=CCCC1(C)Oc2c(C)cc3c4ccc(O)cc4[nH]c3c2C=C1)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B12 compound treatment 148360.0 14200.0 0.44 174800.0 39400.0 1.02 1.0355 0.9291 3558299 ACon1_001954 OCCCc1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B13 mock treatment 140720.0 6590.0 0.2 172000.0 36600.0 0.95 0.8167 0.8398 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B14 mock treatment 147480.0 13300.0 0.41 159360.0 24000.0 0.62 0.7326 0.9803 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B15 compound treatment 128960.0 -5170.0 -0.16 73040.0 -62400.0 -1.62 -1.2591 -0.7733 1000142 ACon1_001955 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B16 compound treatment 161760.0 27600.0 0.86 124040.0 -11400.0 -0.3 0.3965 0.4379 3011353 ACon1_001956 Oc1ccccc1C(=O)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B17 compound treatment 185040.0 50900.0 1.58 88320.0 -47100.0 -1.22 0.2503 0.1254 909 ACon1_001957 COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B18 compound treatment 182480.0 48300.0 1.5 115760.0 -19600.0 -0.51 0.6984 0.4413 1020611 ACon1_001958 Oc1cccc2oc(cc(=O)c12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B19 compound treatment 162720.0 28600.0 0.89 148120.0 12700.0 0.33 0.86 0.9096 3557567 ACon1_001959 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](CO)C=C[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B20 compound treatment 165120.0 31000.0 0.96 127600.0 -7800.0 -0.2 0.5356 0.5457 3559544 ACon1_001960 C[C@H]1C[C@H](O)C[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B21 compound treatment 157800.0 23700.0 0.73 157280.0 21900.0 0.57 0.9205 0.9921 3557523 ACon1_001961 C/C/1=C\CC[C@@]2(C)O[C@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B22 compound treatment 157600.0 23500.0 0.73 141480.0 6080.0 0.16 0.6258 0.841 3177322 ACon1_001962 CC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B23 compound treatment 185880.0 51700.0 1.6 128840.0 -6560.0 -0.17 1.0132 0.6284 3054971 ACon1_001963 O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 B24 compound treatment 56920.0 -77200.0 -2.39 58320.0 -77100.0 -2.0 -3.1079 -0.9961 3557449 ACon1_001964 C[C@@]12CCC3[C@@H](CCC4=CC(=O)CC[C@]34C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C01 compound treatment 159200.0 25100.0 0.78 124920.0 -10500.0 -0.27 0.3566 0.4333 3616105 ACon1_001965 COc1ccc2OC3CCN(C3C(=O)NC(Cc4ccccc4)C(=O)N/C=C\c1c2)C(=O)C(NC(=O)C(C)N(C)C)C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C02 compound treatment 189280.0 55100.0 1.71 148040.0 12600.0 0.33 1.4404 0.8278 1034726 ACon1_001966 COc1ccc(cc1)c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C03 compound treatment 201240.0 67100.0 2.08 146680.0 11300.0 0.29 1.6775 0.7989 3557683 ACon1_001967 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O[C@@H]8OC[C@](O)(CO)[C@H]8O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C04 compound treatment 213360.0 79200.0 2.45 155000.0 19600.0 0.51 2.0959 0.836 3616115 ACon1_001968 COc1cc(ccc1O)c2oc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c(O)c3c(=O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C05 compound treatment 132040.0 -2090.0 -0.06 112840.0 -22600.0 -0.59 -0.4604 -0.7805 3555406 ACon1_001969 CON1c2ccccc2[C@@]3(C=C(O)C(=O)N4/C(=C/c5cnc[nH]5)/C(=O)N[C@]143)C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C06 compound treatment 201360.0 67200.0 2.08 173280.0 37900.0 0.98 2.1688 0.9414 3616121 ACon1_001970 CCCCCC(CC(O)CC(=O)OC(CCCCC)CC(CC(=O)O)OC1OC(CO)C(O)C(O)C1O)OC2OC(CO)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C07 compound treatment 11720.0 -122000.0 -3.79 8840.0 -127000.0 -3.29 -5.0073 -0.9975 3616123 ACon1_001971 C/C=C(/C)\C(=O)O[C@H]1[C@H](OC(=O)/C=C/c2ccccc2)[C@@]3([C@H](O)O[C@@]45CCC6[C@@]7(C)CC[C@H](O[C@@H]8O[C@@H]([C@@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@H](O)[C@H](O)[C@H]9O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O[C@@H]%11OC[C@](O)(CO)[C@H]%11O)[C@H]8O[C@@H]%12O[C@H](CO)[C@H](O)[C@H](O)[C@H]%12O)C(=O)O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)C[C@H]3O)C4CC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C08 compound treatment 11680.0 -122000.0 -3.79 8320.0 -127000.0 -3.3 -5.0177 -0.9976 3616129 ACon1_001972 CCCC(O)/C(=C/C1=C(C(=O)CC(CC(=O)O)OC(=O)N)C(=O)c2cccc(O)c2C1=O)/CC(C(=O)O)[N+](C)(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C09 compound treatment 181960.0 47800.0 1.48 116360.0 -19000.0 -0.49 0.698 0.4468 3616135 ACon1_001973 O[C@H]1[C@@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3ccc(C(=O)CCc4ccc(O)cc4)c(O)c3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C10 compound treatment 165760.0 31600.0 0.98 146360.0 11000.0 0.28 0.8942 0.8763 1076495 ACon1_001974 CC1CCCCCC(=O)c2c(O)cc(O)cc2CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C11 mock treatment 156160.0 22000.0 0.68 188680.0 53300.0 1.38 1.4614 0.9469 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C12 mock treatment 179840.0 45700.0 1.42 176880.0 41500.0 1.08 1.7635 0.9909 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C13 compound treatment 191840.0 57700.0 1.79 176200.0 40800.0 1.06 2.0139 0.9688 3616143 ACon1_001975 C/C(=C/CCC(CO)C1CCC2(C)C3CCC4C5(CC35CCC12C)C(O)CC(OC6OC(CO)C(O)C(O)C6O)C4(C)C)/COC7OC(CO)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C14 compound treatment 159480.0 25300.0 0.79 136400.0 996.0 0.03 0.5737 0.73 3616150 ACon1_001976 CCCCCCC(=O)OC1OC(CO)C(O)C2OCC(COC12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C15 mock treatment 185480.0 51300.0 1.59 146560.0 11200.0 0.29 1.33 0.8224 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C16 mock treatment 181680.0 47500.0 1.47 148080.0 12700.0 0.33 1.2746 0.8443 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C17 compound treatment 12080.0 -122000.0 -3.78 8040.0 -127000.0 -3.31 -5.0141 -0.9978 3616151 ACon1_001977 C/C=C(/C)\C(=O)O[C@H]1CC(C)(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]6O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)[C@@H](OC(=O)C)[C@@H](O)[C@@]12COC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C18 compound treatment 175120.0 41000.0 1.27 62440.0 -73000.0 -1.9 -0.4425 -0.1939 3557642 ACon1_001978 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@H](O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5CC[C@@]78OC[C@]9(C8CC(C)(C)C[C@@H]9OC(=O)C)[C@H](O)C[C@]76C)C4(C)C)[C@@H]3O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C19 compound treatment 95400.0 -38700.0 -1.2 36520.0 -98900.0 -2.57 -2.6653 -0.9399 1147 ACon1_001979 COc1c2ccoc2cc3oc(=O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C20 compound treatment 201440.0 67300.0 2.09 151600.0 16200.0 0.42 1.7722 0.833 3558157 ACon1_001980 COc1cc(O)c2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C21 compound treatment 12040.0 -122000.0 -3.78 9360.0 -126000.0 -3.27 -4.9907 -0.9974 3616160 ACon1_001981 CC1OC(OC2C(O)C(O)C(C)OC2OC3C(O)C(O)C(CO)OC3OC4C(O)C(OC(OC5CCC6(C)C(CCC7(C)C6CCC89OCC%10(CCC(C)(C)CC%109)C(O)CC87C)C5(C)C)C4OC%11OC(CO)C(O)C(O)C%11O)C(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C22 compound treatment 168080.0 33900.0 1.05 128240.0 -7160.0 -0.19 0.6122 0.5731 3558367 ACon1_001982 C[C@@H]1C[C@H]2OC[C@@]3(C)CCC[C@](C)(C23)[C@@]1(O)CCc4ccoc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C23 compound treatment 209720.0 75600.0 2.34 173760.0 38400.0 1.0 2.3608 0.9275 3616165 ACon1_001983 COc1ccc(/C=C/C(=O)O[C@@H]2[C@H](O)[C@@H](O)[C@H](C)O[C@H]2OC3C4O[C@]4(CO)[C@@H]5[C@H]3C=COC5O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 C24 compound treatment 133360.0 -772.0 -0.02 117120.0 -18300.0 -0.48 -0.3528 -0.7418 3557295 ACon1_001984 C/C=C/C1=CC(=O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D01 compound treatment 120800.0 -13300.0 -0.41 109280.0 -26100.0 -0.68 -0.7721 -0.9716 3616143 ACon1_001985 C/C(=C/CCC(CO)C1CCC2(C)C3CCC4C5(CC35CCC12C)C(O)CC(OC6OC(CO)C(O)C(O)C6O)C4(C)C)/COC7OC(CO)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D02 compound treatment 102920.0 -31200.0 -0.97 102680.0 -32700.0 -0.85 -1.2851 -0.9979 3559089 ACon1_001986 OC1[C@H](OC(=O)c2cc(O)c(O)c(O)c2)OC3COC(=O)c4cc(O)c(O)c(O)c4-c5c(O)c(O)c(O)cc5C(=O)O[C@@H]1[C@@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D03 compound treatment 145760.0 11600.0 0.36 139120.0 3720.0 0.1 0.323 0.866 3616174 ACon1_001987 OCC1OC(C(OC(=O)c2cc(O)c(O)c(O)c2)C(O)C1O)c3c(O)cc(O)c(C(=O)c4ccc(O)cc4)c3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D04 compound treatment 126040.0 -8090.0 -0.25 82760.0 -52600.0 -1.37 -1.1445 -0.823 3559657 ACon1_001988 COc1cc(O)c(C(=O)CCc2ccc(OC)c(OC)c2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D05 compound treatment 139400.0 5270.0 0.16 143480.0 8080.0 0.21 0.2638 0.9923 3616180 ACon1_001989 CC1C2C(CC3C4CC(O[C@@H]5O[C@H](C)[C@@H](O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)[C@H](O)[C@H]5O)C7CC(O)CCC7(C)C4CCC23C)OC81OCC(C)CC8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D06 compound treatment 170320.0 36200.0 1.12 163440.0 28000.0 0.73 1.308 0.9782 3559746 ACon1_001990 COc1cc2N3[C@H]4[C@H]5[C@H]6C[C@@H]7N(CC[C@@]74c2cc1OC)CC6=CCO[C@H]5CC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D07 compound treatment 120080.0 -14100.0 -0.44 128520.0 -6880.0 -0.18 -0.4343 -0.9228 3553158 ACon1_001991 C[C@H]1OC(=O)[C@@]23C(=C)[C@]4(C)OC(=O)[C@@]31O[C@]5([C@@H]4O)C(=C)[C@@]6(CC[C@]25C)C=CC(=O)OC6(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D08 compound treatment 118360.0 -15800.0 -0.49 114640.0 -20800.0 -0.54 -0.727 -0.9988 3559359 ACon1_001992 O[C@@H]1CO[C@@H](O[C@@H](CCc2ccc(O)c(O)c2)CC(=O)CCc3ccc(O)c(O)c3)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D09 compound treatment 12680.0 -121000.0 -3.76 10720.0 -125000.0 -3.24 -4.9517 -0.9972 3616190 ACon1_001993 C/C=C/[C@H]1[C@@H](C=C(C)[C@H]2CC[C@H](C)C[C@H]12)C(=O)c3c(O)c(c[nH]c3=O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D10 compound treatment 107640.0 -26500.0 -0.82 162160.0 26800.0 0.7 -0.0888 -0.0826 3554007 ACon1_001994 CC1CC2C=CC3COC(=O)C3(C)C2CC1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D11 mock treatment 119000.0 -15100.0 -0.47 132480.0 -2920.0 -0.08 -0.3852 -0.8111 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D12 mock treatment 121920.0 -12200.0 -0.38 133480.0 -1920.0 -0.05 -0.3029 -0.7936 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D13 compound treatment 114920.0 -19200.0 -0.6 141000.0 5600.0 0.15 -0.3181 -0.5191 3559637 ACon1_001995 COC(=O)C12CCC(C)C(C)C2C3=CCC4C5(C)CCC(OC(=O)C)C(C)(C)C5CCC4(C)C3(C)CC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D14 compound treatment 126640.0 -7490.0 -0.23 141400.0 6000.0 0.16 -0.054 -0.1931 3079231 ACon1_001996 CC1(C)O[C@H]2CC(=O)OC[C@@]23[C@H]1CC(=O)[C@]4(C)[C@@H]3CC[C@@]5(C)[C@@H](OC(=O)[C@H]6O[C@]654)c7ccoc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D15 mock treatment 131440.0 -2690.0 -0.08 138000.0 2600.0 0.07 -0.0113 -0.1051 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D16 mock treatment 128000.0 -6130.0 -0.19 129280.0 -6120.0 -0.16 -0.2469 -0.9961 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D17 compound treatment 84560.0 -49600.0 -1.54 42920.0 -92500.0 -2.4 -2.7853 -0.9766 2838 ACon1_001997 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D18 compound treatment 139400.0 5270.0 0.16 170160.0 34800.0 0.9 0.754 0.8216 3559519 ACon1_001998 C[C@@H]1CC[C@]2(C)[C@H](CCC=C2C(=O)O)[C@@]1(C)CCc3ccoc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D19 compound treatment 12840.0 -121000.0 -3.76 8480.0 -127000.0 -3.3 -4.9893 -0.9979 1054601 ACon1_001999 Cc1cc2c3ccccc3[nH]c2c4C=CC(C)(C)Oc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D20 compound treatment 75760.0 -58400.0 -1.81 44200.0 -91200.0 -2.37 -2.9545 -0.9911 3559588 ACon1_002000 OC/C/1=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](O)C/C(=C\CC1)/C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D21 compound treatment 149200.0 15100.0 0.47 143240.0 7840.0 0.2 0.4741 0.9308 3559469 ACon1_002001 CC1(C)CC2C1[C@@H](O)C/C(=C/CCC2=C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D22 compound treatment 148960.0 14800.0 0.46 169480.0 34100.0 0.89 0.9509 0.9533 3557446 ACon1_002002 C[C@@]12C[C@H](O)C3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D23 compound treatment 160040.0 25900.0 0.8 145120.0 9720.0 0.25 0.7461 0.8867 3559627 ACon1_002003 CCCCCCCCC#CCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 D24 compound treatment 83960.0 -50200.0 -1.55 58240.0 -77200.0 -2.0 -2.5169 -0.9921 3557443 ACon1_002004 C[C@@]12C[C@H](O)C3[C@@H](CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E01 mock treatment 150520.0 16400.0 0.51 118320.0 -17100.0 -0.44 0.0452 0.067 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E02 mock treatment 160520.0 26400.0 0.82 131800.0 -3600.0 -0.09 0.5119 0.6221 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E03 compound treatment 57880.0 -76300.0 -2.36 61840.0 -73600.0 -1.91 -3.0222 -0.9945 3557620 ACon1_002005 COC(=O)C(=C)[C@]1(O[C@]2(C)CC1=O)[C@H](C[C@@]3(C)OC(=O)/C(=C/C)/[C@]3(O)CC2)OC(=O)C(=C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E04 compound treatment 143520.0 9390.0 0.29 144680.0 9280.0 0.24 0.3761 0.9956 3616208 ACon1_002006 OCC1OC(OC2OC=C(C(CC(=O)O)C2C=C)C(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E05 compound treatment 132440.0 -1690.0 -0.05 148600.0 13200.0 0.34 0.2054 0.5921 3616212 ACon1_002007 OC1C(O)C(COC(=O)/C=C/c2ccc(O)cc2)OC(OC(=O)/C=C/c3ccc(O)c(O)c3)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E06 compound treatment 159840.0 25700.0 0.8 142040.0 6640.0 0.17 0.6852 0.8407 3558000 ACon1_002008 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)/C=C/c7ccccc7)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E07 compound treatment 128520.0 -5610.0 -0.17 143360.0 7960.0 0.21 0.0232 0.086 3555029 ACon1_002009 COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1OC5OC(COC(=O)CC(C)(O)CC(=O)O)C(O)C(O)C5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E08 compound treatment 141520.0 7390.0 0.23 140000.0 4600.0 0.12 0.2463 0.954 3616218 ACon1_002010 CC1OC(Oc2cc(O)c3c(=O)c(OC4OCC(O)C(O)C4O)c(oc3c2)c5ccc(O)cc5)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E09 mock treatment 116120.0 -18000.0 -0.56 127640.0 -7760.0 -0.2 -0.5373 -0.9054 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E10 mock treatment 113240.0 -20900.0 -0.65 140360.0 4960.0 0.13 -0.3667 -0.5555 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E11 compound treatment 126240.0 -7890.0 -0.24 153840.0 18400.0 0.48 0.1658 0.3083 3616221 ACon1_002011 COc1cc(/C=C/C(=O)OC[C@H]2O[C@@H](O[C@@H]3OC=C[C@H]4[C@H](O)[C@@H]5O[C@]5(CO)[C@H]43)[C@H](O)[C@@H](O)[C@@H]2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E12 compound treatment 147880.0 13700.0 0.43 137640.0 2240.0 0.06 0.3423 0.7962 3616227 ACon1_002012 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](C)[C@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E13 compound treatment 13240.0 -121000.0 -3.75 13360.0 -122000.0 -3.17 -4.8909 -0.9966 3616231 ACon1_002013 C/C(=C/CC[C@@H](CO)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@H]4[C@]5(C[C@@]35CC[C@]12C)[C@@H](O)C[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C4(C)C)/CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E14 compound treatment 144680.0 10500.0 0.33 142760.0 7360.0 0.19 0.3663 0.9674 3614428 ACon1_002014 COC(=O)c1c(C)cc2CC3(Oc2c(C)c1=O)C(C)CCC(C(C)(C)O)C3(C)CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E15 compound treatment 136720.0 2590.0 0.08 141480.0 6080.0 0.16 0.1683 0.9507 3616237 ACon1_002015 CC(=O)O[C@@H]1[C@@H](O)[C@H](OC(=O)c2ccccc2)[C@@H](CO)O[C@H]1Oc3cc(O)cc(O)c3C(=O)c4cccc(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E16 compound treatment 32840.0 -101000.0 -3.14 28680.0 -107000.0 -2.77 -4.18 -0.9981 3616246 ACon1_002016 CC1C2C(CC3C4CC=C5CC(CCC5(C)C4CCC23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)OC91CCC(C)CN9 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E17 mock treatment 121000.0 -13100.0 -0.41 126160.0 -9240.0 -0.24 -0.4575 -0.9684 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E18 mock treatment 133840.0 -292.0 -0.01 135400.0 -3.75 0.0 -0.0065 -0.7147 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E19 compound treatment 145840.0 11700.0 0.36 124840.0 -10600.0 -0.27 0.0624 0.1372 3616250 ACon1_002017 COc1cc(cc(O)c1OC)c2cc(O)c(OC)c(OC)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E20 compound treatment 10640.0 -123000.0 -3.83 9560.0 -126000.0 -3.27 -5.0177 -0.9969 3554291 ACon1_002018 CCCCCCCC(=O)OC1C(OC(=O)/C(=C/C)/C)C(=C2C3OC(=O)C(C)(O)C3(O)C(CC(C)(OC(=O)C)C12)OC(=O)CCC)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E21 compound treatment 135360.0 1230.0 0.04 111480.0 -23900.0 -0.62 -0.4126 -0.6626 3616255 ACon1_002019 CC[C@H]1C(=O)CC2C3CCC4C[C@@H](O)[C@]5(O)C[C@]4(CO5)C3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E22 compound treatment 136520.0 2390.0 0.07 124440.0 -11000.0 -0.28 -0.1491 -0.5066 3558178 ACon1_002020 CC1(O)CCCC2(C)CCC(CC12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E23 compound treatment 144880.0 10700.0 0.33 127640.0 -7760.0 -0.2 0.0928 0.2385 3558962 ACon1_002021 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H](C)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 E24 compound treatment 11880.0 -122000.0 -3.79 15560.0 -120000.0 -3.11 -4.8803 -0.9953 3616265 ACon1_002022 CC(C)c1cc(O)c(C)c(c1O)c2c(C)c(O)cc(C(C)C)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F01 mock treatment 156480.0 22300.0 0.69 121480.0 -13900.0 -0.36 0.2338 0.2993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F02 mock treatment 136520.0 2390.0 0.07 152280.0 16900.0 0.44 0.3624 0.8149 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F03 compound treatment 137200.0 3070.0 0.1 130320.0 -5080.0 -0.13 -0.0262 -0.1609 3616267 ACon1_002023 C[C@H]1O[C@@H](OC2CC3C(=CC2(C)C=C)CCC4C(C)(C)C(CCC34C)O[C@@H]5O[C@@H](CO)[C@H](O)[C@H]5O)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F04 compound treatment 39720.0 -94400.0 -2.93 43400.0 -92000.0 -2.39 -3.7588 -0.995 3559767 ACon1_002024 COc1ccc(/C=C/C(=O)c2c(OC)cc(OC)c(CC=C(C)C)c2OC)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F05 compound treatment 137920.0 3790.0 0.12 143640.0 8240.0 0.21 0.2343 0.96 3616273 ACon1_002025 C[C@H]1O[C@@H](OC(C)(CC/C=C(\C)/C(=O)O)C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F06 compound treatment 132240.0 -1890.0 -0.06 129320.0 -6080.0 -0.16 -0.1532 -0.9088 1020610 ACon1_002026 Oc1ccc2oc(cc(=O)c2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F07 compound treatment 146560.0 12400.0 0.39 151040.0 15600.0 0.41 0.5596 0.9996 3616280 ACon1_002027 CC(=CCCC(C)(O)C1Cc2cc(cc(CC=C(C)C)c2O1)C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F08 compound treatment 118960.0 -15200.0 -0.47 145240.0 9840.0 0.26 -0.1517 -0.2835 3616283 ACon1_002028 CCCCOC(=O)C(N)CCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F09 mock treatment 117840.0 -16300.0 -0.5 133720.0 -1680.0 -0.04 -0.3879 -0.7655 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F10 mock treatment 121760.0 -12400.0 -0.38 154360.0 19000.0 0.49 0.0772 0.1237 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F11 compound treatment 149200.0 15100.0 0.47 123840.0 -11600.0 -0.3 0.1177 0.212 3559302 ACon1_002029 CC(C1CCC2C3CC=C4CC(CC(O)C4(C)C3CCC12C)OC5OC(COC6OC(CO)C(O)C(O)C6O)C(O)C(O)C5O)C7CC(=C(C)C(=O)O7)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F12 compound treatment 123360.0 -10800.0 -0.33 143120.0 7720.0 0.2 -0.0942 -0.242 3553842 ACon1_002030 CC1(C)[C@@H]2CC[C@]3(C2)[C@H](CC[C@@H]3C1=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F13 compound treatment 117120.0 -17000.0 -0.53 133160.0 -2240.0 -0.06 -0.4139 -0.7806 3559459 ACon1_002031 CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F14 compound treatment 126200.0 -7930.0 -0.25 135400.0 -3.75 0.0 -0.1738 -0.7074 3558542 ACon1_002032 COc1cc(/C=C/CO)ccc1O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F15 compound treatment 12800.0 -121000.0 -3.76 11760.0 -124000.0 -3.21 -4.93 -0.9969 3553373 ACon1_002033 CC(=O)OC[C@@]12CCC(=C[C@H]2O[C@@H]3[C@H](O)[C@@H](OC(=O)C)[C@@]1(C)[C@@]43CO4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F16 compound treatment 120200.0 -13900.0 -0.43 124520.0 -10900.0 -0.28 -0.5052 -0.979 3559439 ACon1_002034 C/C=C(/C)\C(=O)OC1Cc2c(OC1(C)C)ccc3ccc(=O)oc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F17 mock treatment 127160.0 -6970.0 -0.22 131520.0 -3880.0 -0.1 -0.2241 -0.9399 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F18 mock treatment 116640.0 -17500.0 -0.54 121560.0 -13800.0 -0.36 -0.6376 -0.9802 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F19 compound treatment 146400.0 12300.0 0.38 123800.0 -11600.0 -0.3 0.0556 0.1146 3559364 ACon1_002035 COc1cc2[nH]c3ccccc3c2cc1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F20 compound treatment 159600.0 25500.0 0.79 121160.0 -14200.0 -0.37 0.2963 0.3399 1308020 ACon1_002036 COc1ccc(cc1)c2cc(=O)c3ccccc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F21 compound treatment 134840.0 708.0 0.02 132920.0 -2480.0 -0.06 -0.0301 -0.4418 1112402 ACon1_002037 COc1ccc2ccc(=O)oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F22 compound treatment 126400.0 -7730.0 -0.24 109120.0 -26300.0 -0.68 -0.6523 -0.9013 3557454 ACon1_002038 C[C@@]12CCC3[C@@H](CC[C@H]4CC(=O)CC[C@@]43C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F23 compound treatment 132800.0 -1330.0 -0.04 145520.0 10100.0 0.26 0.1567 0.5889 3559628 ACon1_002039 CCCCCCCCC#CCCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 F24 compound treatment 94160.0 -40000.0 -1.24 57160.0 -78200.0 -2.03 -2.3133 -0.9718 3557444 ACon1_002040 C[C@@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G01 compound treatment 110440.0 -23700.0 -0.73 98360.0 -37000.0 -0.96 -1.1997 -0.9911 3616293 ACon1_002041 CCC1CN2CCC3(C2CC1/C(=C/OC)/C(=O)OC)C(=O)Nc4cccc(O)c43 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G02 compound treatment 89480.0 -44700.0 -1.38 93600.0 -41800.0 -1.09 -1.7463 -0.9928 3558908 ACon1_002042 CC1(C)CCC[C@@]2(C)C1CC(=O)c3cc(O)c(O)cc32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G03 mock treatment 131320.0 -2810.0 -0.09 147440.0 12000.0 0.31 0.1595 0.4914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G04 mock treatment 137960.0 3830.0 0.12 137520.0 2120.0 0.05 0.1228 0.9389 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G05 compound treatment 128880.0 -5250.0 -0.16 137320.0 1920.0 0.05 -0.0799 -0.4693 3557720 ACon1_002043 COc1cc(O)c2c(=O)c(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H]4O)[C@H](O)[C@H](O)[C@H]3O)c(oc2c1)c6ccc(O)c(O)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G06 compound treatment 148520.0 14400.0 0.45 141880.0 6480.0 0.17 0.4342 0.9113 3616299 ACon1_002044 COC(=O)Cc1c(oc2cc(C)cc(O)c2c1=O)C(=CC(=O)O)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G07 compound treatment 132560.0 -1570.0 -0.05 126960.0 -8440.0 -0.22 -0.1896 -0.8435 3616301 ACon1_002045 O[C@H]1[C@@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](Oc3ccc(C(=O)/C=C/c4ccccc4)c(O)c3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G08 compound treatment 138000.0 3870.0 0.12 132520.0 -2880.0 -0.07 0.0318 0.2247 3616305 ACon1_002046 CC(C)(O)/C=C/C(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G09 compound treatment 131160.0 -2970.0 -0.09 134720.0 -684.0 -0.02 -0.0777 -0.8283 3553481 ACon1_002047 CC(C)(O)CCCC(C)(O)c1ccc(cc1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G10 compound treatment 124640.0 -9490.0 -0.29 127240.0 -8160.0 -0.21 -0.3579 -0.9871 3616309 ACon1_002048 CC1OC(OC2C(O)C(O)C(OC(=O)[C@@]34CCC(C)(C)CC4C5=CCC6[C@@]7(C)CC[C@H](OC8OC(C)C(OC9OCC(O)(COC%10OCC(O)C(OC%11OCC(OC%12OCC(O)(CO)C%12O)C(O)C%11O)C%10O)C9O)C(O)C8O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)CC3)OC2CO)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G11 compound treatment 121360.0 -12800.0 -0.4 125840.0 -9560.0 -0.25 -0.4555 -0.9749 3558718 ACon1_002049 COc1cc(/C=C/c2cc(O)cc(O)c2)ccc1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G12 compound treatment 133160.0 -972.0 -0.03 156080.0 20700.0 0.54 0.3586 0.6664 3616313 ACon1_002050 CC1OC(OC2C(O)C(O)C(COC3OCC(O)C(O)C3O)OC2OC(=O)C45CCC(C)(C)CC5C6=CCC7C8(C)CCC(OC9OC(CO)C(OC%10OC(C(OC%11OCC(O)C(O)C%11O)C(O)C%10O)C(=O)O)C(O)C9O)C(C)(CO)C8CCC7(C)C6(C)CC4)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G13 compound treatment 128560.0 -5570.0 -0.17 133360.0 -2040.0 -0.05 -0.1596 -0.8837 3616315 ACon1_002051 C[C@@H]1C[C@@H](OC(=O)C)C2[C@]3(C)CCC[C@]2(COC3=O)[C@@]1(O)CCc4ccoc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G14 compound treatment 149920.0 15800.0 0.49 138360.0 2960.0 0.08 0.4002 0.8082 3616319 ACon1_002052 C/C=C\C(=C\[C@H](C)C(=O)C[C@H](O)CC1CC(=O)NC(=O)C1)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G15 compound treatment 122200.0 -11900.0 -0.37 124600.0 -10800.0 -0.28 -0.4599 -0.9908 3616320 ACon1_002053 C[C@@H]([C@H]1CC[C@](C)(O1)C=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G16 compound treatment 121560.0 -12600.0 -0.39 120760.0 -14600.0 -0.38 -0.5445 -0.9999 3616324 ACon1_002054 CC1C2C(CC3C4CC=C5CC(CCC5(C)C4CCC23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O)OC81CCC(C)CN8 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G17 compound treatment 130520.0 -3610.0 -0.11 125480.0 -9920.0 -0.26 -0.2615 -0.9302 3616327 ACon1_002055 COc1cc(CC(CO)C(CO)Cc2cc(OC)c(O)c(c2)c3cc(CC(CO)C(CO)Cc4ccc(O)c(OC)c4)cc(OC)c3O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G18 compound treatment 13040.0 -121000.0 -3.75 11920.0 -123000.0 -3.21 -4.9218 -0.997 3553093 ACon1_002056 C[C@H]1[C@H]2[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@]25[C@@H](/C=C/C[C@H](C)\C=C(/C)\[C@@H](O)C(=O)\C=C\C5=O)[C@@H]6O[C@@]61C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G19 mock treatment 136480.0 2350.0 0.07 132000.0 -3400.0 -0.09 -0.0111 -0.0968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G20 mock treatment 126560.0 -7570.0 -0.23 123080.0 -12300.0 -0.32 -0.3923 -0.9883 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G21 compound treatment 128680.0 -5450.0 -0.17 117480.0 -17900.0 -0.47 -0.4488 -0.9058 3616329 ACon1_002057 CC1=CC[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G22 compound treatment 139360.0 5230.0 0.16 124920.0 -10500.0 -0.27 -0.0781 -0.2463 3616332 ACon1_002058 OC1COC(OCC2OC(O[C@H](C#N)c3ccccc3)C(O)C(O)C2O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G23 compound treatment 125960.0 -8170.0 -0.25 123800.0 -11600.0 -0.3 -0.3922 -0.9962 3616337 ACon1_002059 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/C1CC(=O)OCC(O)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 G24 compound treatment 77600.0 -56500.0 -1.75 71240.0 -64200.0 -1.67 -2.4174 -0.9997 3616341 ACon1_002060 COc1c(O)c(C(=O)/C=C\c2ccccc2)c(OC)c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H01 compound treatment 158440.0 24300.0 0.75 139760.0 4360.0 0.11 0.6126 0.8043 3616345 ACon1_002061 CC1CCC2(C)C(CC(O)C(O)C32CO3)C1(C)CCC4=CC(O)OC4=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H02 compound treatment 112560.0 -21600.0 -0.67 127640.0 -7760.0 -0.2 -0.6153 -0.8813 3559239 ACon1_002062 O[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](O)[C@H]1OC(=O)c4cc(O)c(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H03 mock treatment 158400.0 24300.0 0.75 161880.0 26500.0 0.69 1.0181 0.999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H04 mock treatment 164280.0 30100.0 0.93 159200.0 23800.0 0.62 1.0977 0.9799 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H05 compound treatment 148480.0 14300.0 0.44 167440.0 32000.0 0.83 0.9029 0.9568 3616347 ACon1_002063 CC(CC/C=C(\C)/C(=O)O)C1CC(O)C2(C)C3CCC4C5(CC35CC(O)C12C)CCC(OC6OCC(O)C(O)C6O)C4(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H06 compound treatment 152200.0 18100.0 0.56 143480.0 8080.0 0.21 0.5442 0.9103 450 ACon1_002064 COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H07 compound treatment 99520.0 -34600.0 -1.07 101840.0 -33600.0 -0.87 -1.375 -0.9947 3616351 ACon1_002065 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OC(=O)[C@@]34CCC(C)(C)CC4C5=CCC6[C@@]7(C)CC[C@H](OC8OC(CO)C(OC9OCC(O)C(O)C9O)C(O)C8O)C(C)(C)C7CC[C@@]6(C)[C@]5(C)CC3O)O[C@H]2CO)[C@H](O)[C@H](O)[C@H]1O[C@H]%10OC[C@](O)(CO)[C@H]%10O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H08 compound treatment 12560.0 -122000.0 -3.77 12040.0 -123000.0 -3.21 -4.9301 -0.9968 3551814 ACon1_002066 CC(=CCc1c(O)c(CC=C(C)C)c2OC(CC(=O)c2c1O)c3ccc(O)cc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H09 compound treatment 166120.0 32000.0 0.99 143640.0 8240.0 0.21 0.8522 0.8404 3553447 ACon1_002067 CC(C)(C1CC[C@@]2(C)O[C@](C)(CCC2[C@@]1(C)CC(=O)O)C=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H10 compound treatment 88080.0 -46100.0 -1.43 138880.0 3480.0 0.09 -0.9451 -0.661 3557584 ACon1_002068 C/C(=C\CO)/CC[C@H]1C(=C)CCC2[C@@](C)(CCC[C@]12C)C=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H11 compound treatment 144640.0 10500.0 0.33 151800.0 16400.0 0.43 0.5315 0.9912 2321 ACon1_002069 COc1ccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc2c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H12 compound treatment 142200.0 8070.0 0.25 144920.0 9520.0 0.25 0.3516 1.0 3553497 ACon1_002070 CC(C)[C@]1(O)CC[C@]2(C)CC=C(C)C[C@H](O)[C@@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H13 compound treatment 11680.0 -122000.0 -3.79 11840.0 -124000.0 -3.21 -4.953 -0.9965 3187885 ACon1_002071 CC[C@H]([C@H]1O[C@@](CC)(C[C@@H]1C)[C@H]2CC[C@](O)(CC)[C@H](C)O2)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H14 compound treatment 147520.0 13400.0 0.41 156120.0 20700.0 0.54 0.6739 0.9917 3559539 ACon1_002072 C[C@H]1CCC2OC32CC4(O)OC(=O)C(=C4[C@@H](OC(=O)C(=C)C)[C@]13C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H15 compound treatment 143600.0 9470.0 0.29 155840.0 20400.0 0.53 0.5829 0.9609 3616359 ACon1_002073 CC(CNC(=O)CC[C@]1(C)[C@@H](CC(=O)N)[C@H]2N=C1/C(=C/3\N=C(/C=C/4\N=C(/C(=C\5/[C@@H](CCC(=O)N)[C@](C)(CC(=O)N)[C@@]2(C)N5[Co+]C#N)/C)\[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)\C(C)(C)[C@@H]3CCC(=O)N)/C)OP(=O)(O)O[C@@H]6[C@H](O)[C@@H](O[C@H]6CO)n7cnc8cc(C)c(C)cc78 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H16 compound treatment 162200.0 28100.0 0.87 151440.0 16000.0 0.42 0.9096 0.9432 3559651 ACon1_002074 COc1ccc2C(=O)/C(=C(\O)/c3ccccc3)/Oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H17 compound treatment 137200.0 3070.0 0.1 131800.0 -3600.0 -0.09 0.001 0.0076 3557456 ACon1_002075 C[C@H](CCC(=O)O)[C@H]1CCC2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3C=C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H18 compound treatment 156080.0 21900.0 0.68 133800.0 -1600.0 -0.04 0.4514 0.6625 3559549 ACon1_002076 C/C=C(/CO)\C(=O)O[C@@H]1CC[C@H]2C(=O)c3occ(C)c3C[C@]2(C)[C@H]1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H19 mock treatment 142320.0 8190.0 0.25 141120.0 5720.0 0.15 0.2844 0.9675 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H20 mock treatment 151680.0 17500.0 0.54 138760.0 3360.0 0.09 0.4461 0.8102 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H21 compound treatment 131880.0 -2250.0 -0.07 164840.0 29400.0 0.76 0.4915 0.6399 3559433 ACon1_002077 CC#CCc1cc2ccccc2c(=O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H22 compound treatment 84200.0 -49900.0 -1.55 64440.0 -71000.0 -1.84 -2.3978 -0.9962 3557447 ACon1_002078 CC(=O)[C@H]1CCC2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H23 compound treatment 142080.0 7950.0 0.25 160240.0 24800.0 0.65 0.6304 0.9128 3063892 ACon1_002079 COc1cc2ccc(=O)oc2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 H24 compound treatment 14880.0 -119000.0 -3.69 12400.0 -123000.0 -3.2 -4.8726 -0.9974 3559653 ACon1_002080 O/C(=C\C(=O)/C=C/c1ccc(O)cc1)/C=C/c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I01 compound treatment 133080.0 -1050.0 -0.03 134840.0 -564.0 -0.01 -0.0334 -0.9348 3616365 ACon1_002081 C[C@]1(CN2C3C4C(O)[C@H]5C(O)C6[C@]73CC(=O)C1)C7[C@@H]2C[C@@]46CC5=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I02 compound treatment 14000.0 -120000.0 -3.72 18680.0 -117000.0 -3.03 -4.7765 -0.9948 3616368 ACon1_002082 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C(O)C(O)C6O)C(=O)O)C(CO)(CO)C5CC[C@]43C)[C@@H]2C1)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I03 compound treatment 148960.0 14800.0 0.46 132440.0 -2960.0 -0.08 0.2704 0.5805 3558097 ACon1_002083 COc1cc(C[C@@H]2[C@@H](Cc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)COC2=O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I04 compound treatment 78400.0 -55700.0 -1.73 92560.0 -42800.0 -1.11 -2.0082 -0.9774 3559868 ACon1_002084 OC1C2NCCc3cc4OCOc4c(-c5ccccc15)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I05 mock treatment 149480.0 15300.0 0.48 131200.0 -4200.0 -0.11 0.259 0.5309 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I06 mock treatment 153560.0 19400.0 0.6 122320.0 -13100.0 -0.34 0.1853 0.268 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I07 compound treatment 11240.0 -123000.0 -3.81 11840.0 -124000.0 -3.21 -4.9627 -0.9964 3616375 ACon1_002085 CC(=CCC[C@@](C)(O)[C@H]1CC[C@]2(C)C1CC(O)C3[C@@]2(C)CCC4C(C)(C)[C@@H](O)C[C@@H](O)[C@@]43C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I08 compound treatment 133960.0 -172.0 -0.01 132360.0 -3040.0 -0.08 -0.0597 -0.753 3616379 ACon1_002086 CCC(C)C(O)C(C)(O)/C=C/C1=CC2=C(Cl)C(=O)C(C)(O)C(O)C2CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I09 compound treatment 111920.0 -22200.0 -0.69 105760.0 -29600.0 -0.77 -1.0313 -0.9984 3558841 ACon1_002087 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I10 compound treatment 14760.0 -119000.0 -3.7 17800.0 -118000.0 -3.06 -4.776 -0.9955 3616383 ACon1_002088 CCCCCC(=O)Cc1cc(O)c(O)c2Oc3c(CCCCC)c(C(=O)O)c(O)cc3OC(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I11 compound treatment 143680.0 9550.0 0.3 123080.0 -12300.0 -0.32 -0.0172 -0.0395 3616384 ACon1_002089 OCC12OC2C(O)C3C=COC(OC4OC(COC(=O)/C=C/c5ccccc5)C(O)C(O)C4O)C31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I12 compound treatment 36680.0 -97500.0 -3.02 34200.0 -101000.0 -2.63 -3.9945 -0.9976 3616386 ACon1_002090 CO[C@H]1[C@H](O)[C@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)[C@@H](CC[C@]45O)C6=CC(=O)OC6)C2)O[C@@H](C)[C@@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I13 compound treatment 34880.0 -99300.0 -3.08 39360.0 -96000.0 -2.5 -3.9391 -0.9946 3616388 ACon1_002091 CC(=C)C(=O)O[C@H]1C[C@@]2(C)O[C@@H]2[C@H]3O[C@H]3C(=C)[C@@H](O)[C@H]4OC(=O)C(=C)[C@@H]41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I14 compound treatment 127560.0 -6570.0 -0.2 131440.0 -3960.0 -0.1 -0.2168 -0.9501 3558106 ACon1_002092 OC[C@H]1O[C@@H](Oc2ccc3c(=O)c(coc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I15 compound treatment 152480.0 18300.0 0.57 149960.0 14600.0 0.38 0.6694 0.9804 3616390 ACon1_002093 CC(=O)O[C@@H]1[C@@H](O)[C@H](OC(=O)c2ccccc2)[C@@H](CO)O[C@H]1Oc3cc(O)cc(O)c3C(=O)c4cc(O)cc(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I16 compound treatment 136920.0 2790.0 0.09 150120.0 14700.0 0.38 0.3315 0.8456 959 ACon1_002094 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I17 compound treatment 137040.0 2910.0 0.09 147360.0 12000.0 0.31 0.2834 0.8761 3557761 ACon1_002095 OCC1OC(OCC2OC(NCCc3ccc(O)cc3)C(O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I18 compound treatment 136520.0 2390.0 0.07 141960.0 6560.0 0.17 0.1728 0.9303 3553773 ACon1_002096 CC/C=C\[C@H](O)[C@H](O)C1=C(C)C(=O)[C@@]2(O1)C(O)[C@](NC2=O)(OC)C(=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I19 compound treatment 155840.0 21700.0 0.67 152000.0 16600.0 0.43 0.7805 0.9769 3616392 ACon1_002097 Cc1cc(O)c(O)c(c1)C(=O)C(=O)c2c(O)cc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I20 compound treatment 149800.0 15700.0 0.49 145000.0 9600.0 0.25 0.5196 0.952 3552073 ACon1_002098 C/C=C/C=C/C(=O)C1=C(O)C(=C(O)C(C)(O)C1=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I21 mock treatment 139960.0 5830.0 0.18 134080.0 -1320.0 -0.03 0.1034 0.5623 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I22 mock treatment 158720.0 24600.0 0.76 130440.0 -4960.0 -0.13 0.4475 0.5792 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I23 compound treatment 147440.0 13300.0 0.41 145480.0 10100.0 0.26 0.4767 0.976 3616393 ACon1_002099 C/C=C\1/C(CC(=O)OCCc2ccc(O)c(O)c2)C(=COC1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 I24 compound treatment 115320.0 -18800.0 -0.58 100160.0 -35200.0 -0.92 -1.0597 -0.9762 3553755 ACon1_002100 CC(O)CC1CCC(O1)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J01 compound treatment 60440.0 -73700.0 -2.28 68880.0 -66500.0 -1.73 -2.8368 -0.9906 3616395 ACon1_002101 Oc1ccc(cc1)[C@H]2[C@@H]([C@@H]3[C@H](c4ccc(O)cc4)c5c(O)cc(O)cc5OC3=O)C(=O)Oc6cc(O)cc(O)c26 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J02 compound treatment 31160.0 -103000.0 -3.19 43880.0 -91500.0 -2.38 -3.9376 -0.9895 3559240 ACon1_002102 O[C@H]1[C@H]2[C@H](CC(=O)O)C(=O)O[C@@H]3C(COC(=O)c4cc(O)c(O)c(O)c4)O[C@@H](OC(=O)c5cc(O)c(O)c(O)c5)C(OC(=O)c6cc(O)c(O)c(OC1=O)c26)[C@@H]3OC(=O)c7cc(O)c(O)c(O)c7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J03 compound treatment 112800.0 -21300.0 -0.66 126280.0 -9120.0 -0.24 -0.635 -0.9043 3616397 ACon1_002103 COc1cc(cc2cc(oc12)c3ccc4OCOc4c3)C(O)CCOC5OC(CO)C(O)C(O)C5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J04 compound treatment 140800.0 6670.0 0.21 158960.0 23600.0 0.61 0.5789 0.8961 3559759 ACon1_002104 CC[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c3ccnc4ccc(OC)cc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J05 mock treatment 133880.0 -252.0 -0.01 131960.0 -3440.0 -0.09 -0.0688 -0.7659 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J06 mock treatment 124680.0 -9450.0 -0.29 115240.0 -20200.0 -0.52 -0.5775 -0.9622 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J07 compound treatment 125800.0 -8330.0 -0.26 131880.0 -3520.0 -0.09 -0.2473 -0.9028 3616398 ACon1_002105 Cc1cc2c(CO)cc(O)cc2o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J08 compound treatment 121440.0 -12700.0 -0.39 123160.0 -12200.0 -0.32 -0.503 -0.9945 1066 ACon1_002106 OC1OCC=C2OC(=O)C=C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J09 compound treatment 32000.0 -102000.0 -3.16 31320.0 -104000.0 -2.7 -4.1499 -0.9969 3555011 ACon1_002107 COC1CC(OC2CCC3(C)C(CCC4C3CCC5(C)C(C(CC45O)OC(=O)C)C6=CC(=O)OC6)C2)OC(C)C1OC7OC(COC8OC(CO)C(O)C(O)C8O)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J10 compound treatment 133880.0 -252.0 -0.01 127240.0 -8160.0 -0.21 -0.1555 -0.7326 3558451 ACon1_002108 CC1=C2CCC(C)(O)C=C2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J11 compound treatment 131400.0 -2730.0 -0.08 141440.0 6040.0 0.16 0.051 0.2864 3559926 ACon1_002109 CC1CCC(=C)/C(=C\C=C/CC1(C)CCC2=CCOC2=O)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J12 compound treatment 118400.0 -15700.0 -0.49 107360.0 -28000.0 -0.73 -0.8599 -0.9809 3559949 ACon1_002110 C/C=C(/C)\C(=O)OC(C)(C)C1Cc2cc3ccc(=O)oc3cc2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J13 compound treatment 27280.0 -107000.0 -3.31 20160.0 -115000.0 -2.99 -4.4584 -0.9987 3553079 ACon1_002111 C[C@H]1[C@H]2[C@@H](CC1=O)C(=C)C[C@@H](OC(=O)/C(=C/CO)/COC(=O)/C(=C/CO)/C)C3[C@@H]2OC(=O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J14 compound treatment 127240.0 -6890.0 -0.21 128640.0 -6760.0 -0.18 -0.2753 -0.9953 3083213 ACon1_002112 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc3ccc(O)cc32)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J15 compound treatment 121120.0 -13000.0 -0.4 134920.0 -484.0 -0.01 -0.294 -0.7288 3558672 ACon1_002113 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C/C=C/3\[C@H](O)COC3=O)C(=C)CC[C@H]12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J16 compound treatment 127200.0 -6930.0 -0.21 118040.0 -17400.0 -0.45 -0.4709 -0.9424 3559659 ACon1_002114 CC(=CCn1cnc(N)c2ncnc12)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J17 compound treatment 47880.0 -86300.0 -2.67 49360.0 -86000.0 -2.24 -3.4706 -0.9961 3141 ACon1_002115 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)/C=C/c6cc(OC)c(OC)c(OC)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J18 compound treatment 133360.0 -772.0 -0.02 139680.0 4280.0 0.11 0.0617 0.5425 2107849 ACon1_002116 C[C@@H]1CCC(=C)/C(=C\C=C/C[C@@]1(C)CCc2ccoc2)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J19 compound treatment 118280.0 -15900.0 -0.49 121760.0 -13600.0 -0.35 -0.598 -0.9872 1054600 ACon1_002117 COc1cc(C=O)cc2c3ccccc3[nH]c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J20 compound treatment 128600.0 -5530.0 -0.17 119960.0 -15400.0 -0.4 -0.4049 -0.928 1024517 ACon1_002118 COc1cc2CCNC(C)c2cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J21 mock treatment 136880.0 2750.0 0.09 132760.0 -2640.0 -0.07 0.0116 0.1064 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J22 mock treatment 127640.0 -6490.0 -0.2 126920.0 -8480.0 -0.22 -0.2981 -0.999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J23 compound treatment 134480.0 348.0 0.01 133800.0 -1600.0 -0.04 -0.0218 -0.5073 1528803 ACon1_002119 CC1(C)C2(C)CCC1(OC2=O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 J24 compound treatment 114600.0 -19500.0 -0.61 88720.0 -46700.0 -1.21 -1.2856 -0.9484 3559578 ACon1_002120 COC(=O)/C=C(/CC[C@@H]1C(=C)CC[C@@H]2C(C)(C)C[C@@H](O)C[C@@]12C)\COC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K01 compound treatment 70320.0 -63800.0 -1.98 111160.0 -24200.0 -0.63 -1.8435 -0.8884 3553784 ACon1_002121 CC[C@@H]1[C@@H](O)N2[C@H]3C[C@@]45C(O)C3C1CC2[C@@H]5N(C)c6ccccc64 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K02 compound treatment 69960.0 -64200.0 -1.99 96520.0 -38900.0 -1.01 -2.1204 -0.9507 3557326 ACon1_002122 CC[C@H](C)[C@H]1NC(=O)[C@@H]2C[C@@]3([C@@H](Nc4ccccc43)N2C1=O)C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K03 compound treatment 98840.0 -35300.0 -1.09 124800.0 -10600.0 -0.28 -0.968 -0.8584 3558174 ACon1_002123 CC(O)CCC1=CCC2C(CC1C)OC(=O)C2=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K04 compound treatment 151080.0 16900.0 0.53 158760.0 23400.0 0.61 0.8004 0.9974 3559931 ACon1_002124 CC(=O)NCCCN(CCCCN(CCCNC(=O)/C=C/c1ccc(O)cc1)C(=O)C)C(=O)/C=C/c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K05 compound treatment 147880.0 13700.0 0.43 120760.0 -14600.0 -0.38 0.0322 0.0563 3552912 ACon1_002125 C[C@]12O[C@@H]2CC3C(C)(C)CCC[C@]3(C)[C@]41CC[C@](C)(CC(=O)O)O4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K06 compound treatment 145600.0 11500.0 0.36 146240.0 10800.0 0.28 0.4504 0.9934 3616399 ACon1_002126 COc1c(C2OCC(OC(=O)C)C(OC(=O)C)C2OC(=O)C)c(O)cc3oc(cc(=O)c13)c4ccc(OC5OC(CO)C(O)C(O)C5O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K07 mock treatment 146920.0 12800.0 0.4 114800.0 -20600.0 -0.54 -0.0984 -0.1477 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K08 mock treatment 129240.0 -4890.0 -0.15 112960.0 -22400.0 -0.58 -0.5195 -0.8622 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K09 compound treatment 131520.0 -2610.0 -0.08 119360.0 -16000.0 -0.42 -0.352 -0.8289 3616400 ACon1_002127 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K10 compound treatment 136560.0 2430.0 0.08 148200.0 12800.0 0.33 0.2883 0.8457 3616402 ACon1_002128 CC1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](OC6OC(C)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6O)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K11 compound treatment 145440.0 11300.0 0.35 128520.0 -6880.0 -0.18 0.1213 0.3083 3616404 ACon1_002129 CC(C)C1CCC(=C2CCC(=CC12)C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K12 compound treatment 53520.0 -80600.0 -2.5 48280.0 -87100.0 -2.26 -3.3668 -0.9988 3616405 ACon1_002130 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(CO)[C@@H](CC[C@@H]4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K13 compound treatment 94960.0 -39200.0 -1.21 95280.0 -40100.0 -1.04 -1.5954 -0.9971 3616407 ACon1_002131 C[C@@H]1[C@@H](C)c2ncccc2C(=O)OC[C@]3(C)O[C@@]45[C@H](OC(=O)C)[C@H]3[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@]5(COC(=O)C)[C@@H](OC(=O)c6ccccc6)[C@@H](O)[C@H](OC1=O)[C@]4(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K14 compound treatment 124040.0 -10100.0 -0.31 124680.0 -10700.0 -0.28 -0.4181 -0.9983 3616409 ACon1_002132 CCN1C[C@]2(C)CC[C@H](O)[C@]3([C@@H]4C[C@H]5[C@H](O)[C@@H]4[C@](O)(C[C@@H]5OC)[C@]6(O)[C@@H](OC)C32)[C@H]16 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K15 mock treatment 120400.0 -13700.0 -0.43 124160.0 -11200.0 -0.29 -0.5074 -0.9832 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K16 mock treatment 125560.0 -8570.0 -0.27 118880.0 -16500.0 -0.43 -0.4914 -0.9733 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K17 compound treatment 103400.0 -30700.0 -0.95 105120.0 -30300.0 -0.79 -1.2297 -0.9955 3616411 ACon1_002133 CC(CO)C(=O)O[C@H]1CC(C)(C=C)C([C@H]2OC(=O)C(=C)[C@@H]21)C(=C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K18 compound treatment 135840.0 1710.0 0.05 136080.0 676.0 0.02 0.0498 0.8939 3616413 ACon1_002134 OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K19 compound treatment 128280.0 -5850.0 -0.18 138280.0 2880.0 0.07 -0.0754 -0.3843 3616414 ACon1_002135 CC(C)(O)/C=C/C1=CC(O)C(C)(O)CC1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K20 compound treatment 156480.0 22300.0 0.69 124480.0 -10900.0 -0.28 0.2889 0.3861 3557979 ACon1_002136 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C3C1CC(O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K21 compound treatment 132480.0 -1650.0 -0.05 116680.0 -18700.0 -0.49 -0.3802 -0.7772 1116462 ACon1_002137 Nc1c(O)cccc1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K22 compound treatment 118640.0 -15500.0 -0.48 137200.0 1800.0 0.05 -0.3064 -0.6354 3559068 ACon1_002138 COc1cc(cc(OC)c1OC)C2OC(C(C)C2C)c3cc(OC)c(OC)c(OC)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K23 mock treatment 135520.0 1390.0 0.04 132000.0 -3400.0 -0.09 -0.0321 -0.3266 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 K24 mock treatment 99440.0 -34700.0 -1.07 144360.0 8960.0 0.23 -0.5955 -0.5415 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L01 compound treatment 94280.0 -39900.0 -1.23 136720.0 1320.0 0.03 -0.8489 -0.6873 3615597 ACon1_002139 COC1OC(=O)C(CCC2(C)C(C)CCC3(C)C2CC(O)C(O)C43CO4)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L02 compound treatment 60880.0 -73300.0 -2.27 70320.0 -65100.0 -1.69 -2.8007 -0.9895 3557877 ACon1_002140 OC[C@H]1O[C@@H](OC(CCc2ccc(O)cc2)CC(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L03 compound treatment 111080.0 -23100.0 -0.71 142280.0 6880.0 0.18 -0.3787 -0.5144 3616416 ACon1_002141 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)[C@@H](OC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L04 compound treatment 130760.0 -3370.0 -0.1 137480.0 2080.0 0.05 -0.0357 -0.3039 1091317 ACon1_002142 CC(C)CC(=O)CC1(C)CCC(O1)c2ccoc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L05 compound treatment 120160.0 -14000.0 -0.43 131480.0 -3920.0 -0.1 -0.3782 -0.8504 3616418 ACon1_002143 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccc(O)cc6)[C@H](OC(=O)C)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L06 compound treatment 9120.0 -125000.0 -3.87 10720.0 -125000.0 -3.24 -5.0297 -0.9961 3552811 ACon1_002144 C[C@@H]1OC(CC[C@@H]1O)O[C@@]23C(=O)C[C@](C)(O)C[C@@]3(O)C=CC4=C2C(=O)c5ccc([C@H]6C[C@@H](O[C@H]7CC[C@H](O[C@H]8C[C@@H](O)[C@H](O)[C@@H](C)O8)[C@H](C)O7)[C@H](O)[C@@H](C)O6)c(O)c5C4=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L07 mock treatment 125880.0 -8250.0 -0.26 119600.0 -15800.0 -0.41 -0.4711 -0.974 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L08 mock treatment 133240.0 -892.0 -0.03 136680.0 1280.0 0.03 0.0039 0.0906 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L09 compound treatment 125440.0 -8690.0 -0.27 127760.0 -7640.0 -0.2 -0.3309 -0.9888 3558762 ACon1_002145 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@](C)(O)[C@H](C[C@@]31O)OC(=O)/C=C/c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L10 compound treatment 121520.0 -12600.0 -0.39 118280.0 -17100.0 -0.44 -0.5909 -0.9979 3558525 ACon1_002146 COC(=O)CCCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L11 compound treatment 118960.0 -15200.0 -0.47 144920.0 9520.0 0.25 -0.1576 -0.2966 3558176 ACon1_002147 COc1cc(O)c2C(=O)[C@H](OC(=O)C)[C@H](Oc2c1)c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L12 compound treatment 119760.0 -14400.0 -0.45 119200.0 -16200.0 -0.42 -0.6126 -0.9996 3554563 ACon1_002148 COC(=O)[C@]12C(=O)C(C)C(=O)[C@]2(C)C(=C[C@@H]3[C@]1(C)CC[C@@H]4C(C)(C)[C@H](CC[C@]43CO)OC(=O)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L13 compound treatment 15840.0 -118000.0 -3.67 11240.0 -124000.0 -3.23 -4.8729 -0.998 3559438 ACon1_002149 CC(C)CC(=O)OC1C(Oc2ccc3ccc(=O)oc3c12)C(C)(C)OC(=O)CC(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L14 compound treatment 125840.0 -8290.0 -0.26 112440.0 -23000.0 -0.6 -0.6036 -0.9291 3559513 ACon1_002150 C[C@]1(C[C@]23CCC4[C@](C)(CO)CCC[C@@]4(C)C3CC1)C=C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L15 mock treatment 121760.0 -12400.0 -0.38 126640.0 -8760.0 -0.23 -0.4321 -0.9691 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L16 mock treatment 125880.0 -8250.0 -0.26 118080.0 -17300.0 -0.45 -0.4991 -0.9641 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L17 compound treatment 109360.0 -24800.0 -0.77 125560.0 -9840.0 -0.26 -0.7236 -0.8944 3173755 ACon1_002151 C[C@@]12CC(=O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L18 compound treatment 108800.0 -25300.0 -0.78 117440.0 -18000.0 -0.47 -0.885 -0.9692 3553165 ACon1_002152 CC#CC#C/C=C\1/OC2(OC=CC2OC(=O)C=C(C)C)C=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L19 compound treatment 53240.0 -80900.0 -2.51 59240.0 -76200.0 -1.98 -3.1716 -0.9932 3616420 ACon1_002153 COc1cc(O)c(O)c(OC)c1C(=O)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L20 compound treatment 105680.0 -28500.0 -0.88 132920.0 -2480.0 -0.06 -0.669 -0.7568 3557450 ACon1_002154 C[C@@]12CCC3[C@@H](CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L21 compound treatment 116200.0 -17900.0 -0.56 135120.0 -284.0 -0.01 -0.3981 -0.7164 1023016 ACon1_002155 COc1ccc2ccc(=O)oc2c1CC=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L22 compound treatment 98840.0 -35300.0 -1.09 130560.0 -4840.0 -0.13 -0.8622 -0.7833 3557458 ACon1_002156 C[C@@]12CCC3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)C2CC[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L23 mock treatment 123040.0 -11100.0 -0.34 130200.0 -5200.0 -0.14 -0.3386 -0.9169 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 L24 mock treatment 111840.0 -22300.0 -0.69 144240.0 8840.0 0.23 -0.3261 -0.448 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M01 compound treatment 122920.0 -11200.0 -0.35 172360.0 37000.0 0.96 0.4333 0.4244 3555864 ACon1_002157 OC(=O)CCCCCCCC(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M02 compound treatment 5720.0 -128000.0 -3.98 8640.0 -127000.0 -3.29 -5.1424 -0.9956 3616422 ACon1_002158 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](OC6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M03 compound treatment 63480.0 -70700.0 -2.19 137520.0 2120.0 0.05 -1.5091 -0.6891 3557282 ACon1_002159 C[C@@H]1O[C@@H](Oc2ccc(cc2)c3coc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)ccc4c3=O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M04 compound treatment 95680.0 -38500.0 -1.19 107800.0 -27600.0 -0.72 -1.3496 -0.9705 3553312 ACon1_002160 CC(=O)NC1CCCN(O)C(=O)/C=C(\C)/CCOC(=O)C(CCCN(O)C(=O)/C=C(\C)/CCOC(=O)C(CCCN(O)C(=O)/C=C(\C)/CCOC1=O)NC(=O)C)NC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M05 compound treatment 64240.0 -69900.0 -2.17 85440.0 -50000.0 -1.3 -2.4492 -0.97 3553564 ACon1_002161 CC(C)c1cc2C(O)[C@H]3OC(=O)[C@@]4(CCCC(C)(C)C34)c2c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M06 compound treatment 93960.0 -40200.0 -1.24 138040.0 2640.0 0.07 -0.8317 -0.6672 3616424 ACon1_002162 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M07 compound treatment 85680.0 -48500.0 -1.5 131320.0 -4080.0 -0.11 -1.1366 -0.7552 3616426 ACon1_002163 CC1CC(=O)C2C(O)(C1)CC(O)C34OC4c5c(O)cccc5C(=O)C23O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M08 compound treatment 69600.0 -64500.0 -2.0 114560.0 -20800.0 -0.54 -1.7968 -0.8674 3616427 ACon1_002164 CC(=O)OC(C)(C)/C=C/C(=O)[C@](C)(O)[C@H]1C(O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C=C(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M09 mock treatment 128440.0 -5690.0 -0.18 158640.0 23200.0 0.6 0.3022 0.4805 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M10 mock treatment 134880.0 748.0 0.02 125200.0 -10200.0 -0.27 -0.1711 -0.6428 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M11 compound treatment 140160.0 6030.0 0.19 149400.0 14000.0 0.36 0.3892 0.9521 3616429 ACon1_002165 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)[C@@H](OC(=O)/C=C/c4ccc(O)cc4)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M12 compound treatment 26120.0 -108000.0 -3.35 48240.0 -87200.0 -2.26 -3.9679 -0.9819 3616431 ACon1_002166 COc1c(O)cc2oc(cc(=O)c2c1O)c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M13 mock treatment 118720.0 -15400.0 -0.48 124840.0 -10600.0 -0.27 -0.5317 -0.9654 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M14 mock treatment 117960.0 -16200.0 -0.5 139560.0 4160.0 0.11 -0.278 -0.5423 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M15 compound treatment 112040.0 -22100.0 -0.68 142200.0 6800.0 0.18 -0.3592 -0.5081 3616433 ACon1_002167 CC1OC(OC2C(O)C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)C(O)CC7(C(O)CC65C)C(=O)O)C3(C)C)OC2CO)C(O)C(OC8OCC(O)C(O)C8O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M16 compound treatment 116040.0 -18100.0 -0.56 140160.0 4760.0 0.12 -0.309 -0.5383 3616434 ACon1_002168 CC(C)[C@H](NC(=O)[C@H](C)N(C)C)C(=O)N1CC[C@@H]2Oc3ccc(/C=C\NC(=O)[C@H](Cc4ccccc4)NC(=O)C21)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M17 compound treatment 128600.0 -5530.0 -0.17 172760.0 37400.0 0.97 0.5651 0.5734 3616436 ACon1_002169 CC1(CO)CC(=O)CC2(C)C1CCC3=C2COC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M18 compound treatment 128640.0 -5490.0 -0.17 120920.0 -14500.0 -0.38 -0.3864 -0.9356 3554069 ACon1_002170 CC1CCC2C(C)(C)C(=O)CC[C@]2(C)C31Cc4c(O3)c5CN(C(CCC(=O)O)C(=O)O)C(=O)c5cc4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M19 compound treatment 114160.0 -20000.0 -0.62 100040.0 -35400.0 -0.92 -1.0873 -0.9815 3616437 ACon1_002171 CCCc1c(O)c2C(=O)c3c(O)cccc3C(=O)c2cc1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M20 compound treatment 122960.0 -11200.0 -0.35 115960.0 -19400.0 -0.51 -0.602 -0.983 3555795 ACon1_002172 O=C1NC2CCc3nc4ccccc4c(=O)n3C2=Nc5ccccc15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M21 compound treatment 113040.0 -21100.0 -0.65 122720.0 -12700.0 -0.33 -0.6951 -0.9498 3616438 ACon1_002173 O[C@H]1[C@H](O)[C@@H](COC(=O)c2ccc(O)cc2)O[C@@H](Oc3ccc(O)cc3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M22 compound treatment 94920.0 -39200.0 -1.21 119120.0 -16300.0 -0.42 -1.1583 -0.9003 3554747 ACon1_002174 COC1=CC(=O)CC(C)C21Oc3cc(OC)cc(OC)c3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M23 compound treatment 122760.0 -11400.0 -0.35 158160.0 22800.0 0.59 0.1689 0.2455 3554983 ACon1_002175 COc1cc(O)c2C(=O)O[C@@]3(C)C[C@H](O)[C@@H](O)C=C3c2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 M24 compound treatment 28880.0 -105000.0 -3.26 26800.0 -109000.0 -2.82 -4.3013 -0.9974 3616440 ACon1_002176 Oc1ccc(CCCCC(=O)CCc2ccc(O)c(O)c2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N01 compound treatment 111080.0 -23100.0 -0.71 159040.0 23600.0 0.61 -0.0708 -0.0752 3616441 ACon1_002177 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3C=C(CO)[C@@H]4[C@H]3C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H]2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N02 compound treatment 35920.0 -98200.0 -3.04 47160.0 -88200.0 -2.29 -3.773 -0.9903 3557494 ACon1_002178 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N03 compound treatment 7120.0 -127000.0 -3.94 9400.0 -126000.0 -3.27 -5.0978 -0.9958 3616443 ACon1_002179 C[C@@H]1[C@H]2[C@@H](CC1=O)C(=C)C[C@H](OC(=O)C(=C)CO)[C@@H]3[C@@H]2OC(=O)C3=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N04 compound treatment 151400.0 17300.0 0.54 135360.0 -43.8 0.0 0.3775 0.7056 3553392 ACon1_002180 CC(=O)OCC#Cc1ccc(s1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N05 compound treatment 8560.0 -126000.0 -3.89 11120.0 -124000.0 -3.23 -5.0346 -0.9957 3616445 ACon1_002181 C[C@@H]1CCOC(=O)/C=C/C=C\C(=O)O[C@@H]2C[C@H]3O[C@@H]4C=C(CC[C@]4(COC(=O)[C@H]1O)[C@]2(C)[C@@]53CO5)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N06 compound treatment 97520.0 -36600.0 -1.13 109840.0 -25600.0 -0.66 -1.2718 -0.9675 3559417 ACon1_002182 COC(=O)[C@@]1(C)CCC[C@]2(C)[C@@H](CCC3=CC(=O)OC3)C(=CC[C@@H]12)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N07 compound treatment 111880.0 -22300.0 -0.69 119360.0 -16000.0 -0.42 -0.7823 -0.971 3616447 ACon1_002183 CNc1ccccc1C(=O)OC2OC(C)C(O)C(O)C2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N08 compound treatment 127920.0 -6210.0 -0.19 130000.0 -5400.0 -0.14 -0.2354 -0.988 3559635 ACon1_002184 CC(=CC(O)C/C(=C\CCC(C)(O)C=C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N09 mock treatment 134120.0 -11.8 0.0 122920.0 -12500.0 -0.32 -0.2296 -0.7079 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N10 mock treatment 134880.0 748.0 0.02 129880.0 -5520.0 -0.14 -0.0851 -0.5853 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N11 compound treatment 124120.0 -10000.0 -0.31 133840.0 -1560.0 -0.04 -0.2481 -0.7929 3616448 ACon1_002185 CCC[C@@H](O)[C@H](O)[C@@H]1CC(=CC(=O)O1)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N12 compound treatment 127880.0 -6250.0 -0.19 85240.0 -50200.0 -1.3 -1.0586 -0.8034 3558517 ACon1_002186 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N13 mock treatment 120920.0 -13200.0 -0.41 132400.0 -3000.0 -0.08 -0.3446 -0.827 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N14 mock treatment 135920.0 1790.0 0.06 121920.0 -13500.0 -0.35 -0.2086 -0.588 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N15 compound treatment 75760.0 -58400.0 -1.81 20600.0 -115000.0 -2.98 -3.3881 -0.9713 3557442 ACon1_002187 CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)CCC3=C)\CCC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N16 compound treatment 116080.0 -18100.0 -0.56 125200.0 -10200.0 -0.27 -0.583 -0.9418 3552715 ACon1_002188 C[C@@H]1CCC2[C@@H](C)C(=O)OC3O[C@@]4(C)CCC1[C@@]23OO4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N17 compound treatment 105640.0 -28500.0 -0.88 154320.0 18900.0 0.49 -0.2767 -0.2738 3557445 ACon1_002189 CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N18 compound treatment 117880.0 -16300.0 -0.5 127040.0 -8360.0 -0.22 -0.5097 -0.9294 3559502 ACon1_002190 COC(=O)[C@]1(C)CCC[C@@]2(C)C3CC[C@@H]4C[C@]3(CC4=C)CCC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N19 compound treatment 98080.0 -36100.0 -1.12 133640.0 -1760.0 -0.05 -0.8223 -0.7355 3559390 ACon1_002191 Oc1ccc2C(=O)C(C(Oc2c1)c3ccc(O)c(O)c3)C4C(Oc5cc(O)ccc5C4=O)c6ccc(O)c(O)c6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N20 compound treatment 112760.0 -21400.0 -0.66 160280.0 24900.0 0.65 -0.0112 -0.0121 3559784 ACon1_002192 O=C1/C(=C/2\Nc3ccccc3C2=O)/Nc4ccccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N21 compound treatment 121520.0 -12600.0 -0.39 140160.0 4760.0 0.12 -0.1889 -0.461 1090111 ACon1_002193 CC(=C)C1Cc2cc(ccc2O1)C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N22 compound treatment 104000.0 -30100.0 -0.93 114160.0 -21200.0 -0.55 -1.0505 -0.9686 3557455 ACon1_002194 C[C@@]12CCC3[C@@H](CCC4=CC(=O)C=C[C@]34C)C2CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N23 compound treatment 112040.0 -22100.0 -0.68 147280.0 11900.0 0.31 -0.2658 -0.354 3553947 ACon1_002195 CC1=CCC[C@]2(C)CC[C@H](C[C@@H]12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 N24 compound treatment 78800.0 -55300.0 -1.71 84480.0 -50900.0 -1.32 -2.1479 -0.9918 1737132 ACon1_002196 COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c2c34)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O01 compound treatment 104480.0 -29700.0 -0.92 127080.0 -8320.0 -0.22 -0.8026 -0.8503 3554295 ACon1_002197 CCCCCCCC1OC(=O)CCC(O)/C=C/C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O02 compound treatment 132240.0 -1890.0 -0.06 122960.0 -12400.0 -0.32 -0.2701 -0.8219 3616449 ACon1_002198 CC1C(O)C=C2[C@@H](CC[C@@]3(O)[C@](C)([C@H](O)CC[C@]23C)C(=O)O)[C@H]1C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O03 compound treatment 86960.0 -47200.0 -1.46 103960.0 -31400.0 -0.82 -1.6112 -0.9622 3558022 ACon1_002199 C/C/1=C\[C@H](O)C2[C@H](OC(=O)C2=C)/C=C(\CO)/CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O04 compound treatment 95160.0 -39000.0 -1.21 113520.0 -21900.0 -0.57 -1.2559 -0.941 3616451 ACon1_002200 CC(=O)N(O)CCCCCNC(=O)CC(O)(CC(=O)NCCCCCN(O)C(=O)C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O05 compound treatment 6560.0 -128000.0 -3.95 9600.0 -126000.0 -3.27 -5.1064 -0.9955 3616452 ACon1_002201 CCC/C=C/C(=O)OC1C(O)C2(C(O)OC34CCC5C6(C)CCC(OC7OC(C(O)C(OC8OC(CO)C(O)C(O)C8OC9OC(C)C(O)C(O)C9OC%10OCC(O)C(O)C%10O)C7OC%11OC(CO)C(O)C(O)C%11O)C(=O)O)C(C)(C)C6CCC5(C)C4(C)CC2OC(=O)C)C3CC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O06 compound treatment 125880.0 -8250.0 -0.26 133560.0 -1840.0 -0.05 -0.2147 -0.8252 3616299 ACon1_002202 COC(=O)Cc1c(oc2cc(C)cc(O)c2c1=O)C(=CC(=O)O)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O07 compound treatment 106080.0 -28100.0 -0.87 123880.0 -11500.0 -0.3 -0.8263 -0.8989 3616454 ACon1_002203 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(C5CC[C@]43C)C(=O)O)[C@@H]2[C@]1(C)O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O08 compound treatment 112920.0 -21200.0 -0.66 127760.0 -7640.0 -0.2 -0.6052 -0.8814 3616455 ACon1_002204 OC[C@H]1O[C@@H](Oc2c(O)cccc2COC(=O)C3(O)C4C=CC(C5C4C=CC(=O)C5(O)C(=O)OCc6cccc(O)c6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C3=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O09 compound treatment 115440.0 -18700.0 -0.58 139360.0 3960.0 0.1 -0.3368 -0.5727 3616458 ACon1_002205 COc1cc(O)c(C(=O)c2c(O)cc(C)cc2O)c(c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O10 compound treatment 108320.0 -25800.0 -0.8 132560.0 -2840.0 -0.07 -0.6178 -0.7692 1063449 ACon1_002206 COc1c(C)c(OCC=C(C)C)cc(CO)c1CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O11 mock treatment 139320.0 5190.0 0.16 122800.0 -12600.0 -0.33 -0.1179 -0.3232 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O12 mock treatment 131880.0 -2250.0 -0.07 114320.0 -21100.0 -0.55 -0.4367 -0.7908 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O13 compound treatment 121720.0 -12400.0 -0.38 134280.0 -1120.0 -0.03 -0.2926 -0.7586 3616460 ACon1_002207 C[C@H](CO)C1=C(O)C(=O)[C@@]2(C)C/C=C(\C)/CC/C=C(\C)/CC[C@H](O)\C(=C\C[C@H]12)\C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O14 compound treatment 110720.0 -23400.0 -0.73 141640.0 6240.0 0.16 -0.3984 -0.536 3616463 ACon1_002208 OC[C@H]1O[C@@H](OC2OC=C3C(CC4N(CCc5c4[nH]c6ccccc56)C3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O15 compound treatment 77880.0 -56300.0 -1.74 114560.0 -20800.0 -0.54 -1.6154 -0.8851 3616464 ACon1_002209 CC1OC(OC2C(O)C(O)C(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)C8CC7(C(O)CC65C)C(=O)O8)C3(C)C)OC2CO)C(O)C(OC9OCC(O)C(O)C9O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O16 compound treatment 110240.0 -23900.0 -0.74 149720.0 14300.0 0.37 -0.2604 -0.3143 3616465 ACon1_002210 COC1OC2C(c3ccc4OCOc4c13)[N+](C)([O-])CCc5cc6OCOc6cc25 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O17 compound treatment 131480.0 -2650.0 -0.08 154160.0 18800.0 0.49 0.2865 0.5797 3616466 ACon1_002211 CCC(C)C(O)(CC(=O)OCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)C(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O18 compound treatment 101320.0 -32800.0 -1.02 151640.0 16200.0 0.42 -0.4206 -0.3821 3616469 ACon1_002212 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1OC(=O)/C=C/c3ccc(O)c(O)c3)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O19 compound treatment 139720.0 5590.0 0.17 141000.0 5600.0 0.15 0.2253 0.9962 3616471 ACon1_002213 CC(C)CC1NC(=O)C2(O)C1C(C)C(=CC2/C=C(\C)/CCC(O)C(O)/C=C/C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O20 compound treatment 88480.0 -45700.0 -1.41 118000.0 -17400.0 -0.45 -1.32 -0.8888 3554660 ACon1_002214 COC(=O)C1(Cc2ccc(O)c(CC3OC3(C)C)c2)OC(=O)C(=C1c4ccc(O)cc4)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O21 compound treatment 140040.0 5910.0 0.18 159000.0 23600.0 0.61 0.563 0.8799 3616474 ACon1_002215 C[C@H](CC/C=C(\C)/C(=O)OC1OC(CO)C(O)C(O)C1O)[C@H]2CC(OC3OCC(O)C(O)C3O)[C@@]4(C)C5CC[C@@H]6[C@]7(C[C@@]57CC(O)[C@]24C)CC[C@H](O[C@@H]8OC(CO)C(O)C(O)C8OC9OC(CO)C(O)C(O)C9O)C6(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O22 compound treatment 80800.0 -53300.0 -1.65 116080.0 -19300.0 -0.5 -1.5235 -0.8821 3558516 ACon1_002216 COC(=O)C(C(O)c1ccc(O)c(OC)c1)C(CO)Cc2ccc(O)c(OC)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O23 compound treatment 92240.0 -41900.0 -1.3 106000.0 -29400.0 -0.76 -1.458 -0.9681 3616477 ACon1_002217 COC1(C)C(O)C(=O)C(=C(Oc2cc(C)c(C(=O)NCCc3ccc(O)c(O)c3)c(O)c2C)C1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 O24 compound treatment 119080.0 -15100.0 -0.47 132200.0 -3200.0 -0.08 -0.3886 -0.8204 3616478 ACon1_002218 CC1CCC2(C)C(CC(O)C(O)C32CO3)C1(C)CCC4=CC(=O)OC4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P01 compound treatment 99520.0 -34600.0 -1.07 83960.0 -51400.0 -1.34 -1.7035 -0.994 3616479 ACon1_002219 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)O)OC(=O)CCc4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P02 compound treatment 100000.0 -34100.0 -1.06 109400.0 -26000.0 -0.68 -1.2256 -0.9766 3559761 ACon1_002220 CS(=O)(=O)CCC/C(=N\OS(=O)(=O)O)/S[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P03 compound treatment 89240.0 -44900.0 -1.39 112800.0 -22600.0 -0.59 -1.3988 -0.9265 3616481 ACon1_002221 COC(=O)C1=COC(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](OC(=O)/C=C/c4ccc(O)c(O)c4)[C@@H](O)[C@@H]31 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P04 compound treatment 87800.0 -46300.0 -1.44 114320.0 -21100.0 -0.55 -1.4025 -0.9127 3559446 ACon1_002222 COc1cc2OC(C)(C)C=Cc2cc1C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P05 compound treatment 97440.0 -36700.0 -1.14 152200.0 16800.0 0.44 -0.4953 -0.4067 3558885 ACon1_002223 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](C=C)[C@@H]1C[C@@H]3N[C@@H](Cc4c3[nH]c5ccccc45)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P06 compound treatment 109560.0 -24600.0 -0.76 126600.0 -8800.0 -0.23 -0.7001 -0.8807 3558178 ACon1_002224 CC1(O)CCCC2(C)CCC(CC12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P07 compound treatment 97120.0 -37000.0 -1.15 139200.0 3800.0 0.1 -0.7412 -0.6439 3558887 ACon1_002225 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P08 compound treatment 111160.0 -23000.0 -0.71 135720.0 316.0 0.01 -0.4975 -0.6989 3559717 ACon1_002226 CC1(C)CC(=O)c2ccc(O)cc2O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P09 compound treatment 56200.0 -77900.0 -2.41 96280.0 -39100.0 -1.02 -2.4262 -0.9261 3559894 ACon1_002227 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CCC4[C@@]5(C)CCC(=O)C(C)(C)C5C(O)C[C@]43C)C12)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P10 compound treatment 100560.0 -33600.0 -1.04 131800.0 -3600.0 -0.09 -0.8017 -0.7677 3557753 ACon1_002228 CC(O)/C=C/C1(O)C(=CC(=O)CC1(C)C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P11 mock treatment 112920.0 -21200.0 -0.66 118120.0 -17300.0 -0.45 -0.7823 -0.9828 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P12 mock treatment 121680.0 -12500.0 -0.39 127680.0 -7720.0 -0.2 -0.4147 -0.9536 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P13 compound treatment 115640.0 -18500.0 -0.57 112960.0 -22400.0 -0.58 -0.8175 -1.0 3552932 ACon1_002229 C[C@H](CCCC(C)(C(=O)O)C(=O)O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P14 compound treatment 52800.0 -81300.0 -2.52 79880.0 -55500.0 -1.44 -2.802 -0.965 3553129 ACon1_002230 C[C@H]1CC[C@@H]2[C@@H](OC(=O)C2=C)[C@@]3(C)[C@H]1C=CC3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P15 compound treatment 80520.0 -53600.0 -1.66 74120.0 -61300.0 -1.59 -2.3005 -0.9998 346 ACon1_002231 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)[C@@H]4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P16 compound treatment 59600.0 -74500.0 -2.31 94480.0 -40900.0 -1.06 -2.3848 -0.938 3552697 ACon1_002232 C[C@@H]1CC[C@@H]2[C@@H]1[C@H]3[C@@H](CCC2(O)CO)C3(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P17 compound treatment 97840.0 -36300.0 -1.12 128960.0 -6440.0 -0.17 -0.9135 -0.8035 3557610 ACon1_002233 O[C@H]1[C@H](O)[C@@H](OC(=O)c2ccc(O)cc2)[C@H](Oc3ccc(O)cc3)O[C@@H]1COC(=O)CC(=O)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P18 compound treatment 22200.0 -112000.0 -3.47 30200.0 -105000.0 -2.73 -4.3852 -0.9931 3559496 ACon1_002234 COC(=O)C[C@H](C)CC[C@H]1[C@](C)(O)CCC2C(C)(C)CCC[C@]12C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P19 compound treatment 120120.0 -14000.0 -0.43 154680.0 19300.0 0.5 0.0472 0.0712 3554682 ACon1_002235 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@H](C[C@@H]31)OC(=O)C4=CO[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H]6[C@@H](C)[C@H](C[C@@H]64)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P20 compound treatment 76680.0 -57500.0 -1.78 84040.0 -51400.0 -1.33 -2.2024 -0.9899 3557448 ACon1_002236 C[C@@]12CCC3[C@@H](CCc4cc(O)ccc34)C2CC[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P21 compound treatment 91240.0 -42900.0 -1.33 128280.0 -7120.0 -0.19 -1.0706 -0.7979 3559463 ACon1_002237 C/C(=C\CCC(C)(O)C=C)/CCC(O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P22 compound treatment 50080.0 -84100.0 -2.6 51680.0 -83700.0 -2.18 -3.3797 -0.996 3557457 ACon1_002238 C[C@@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C2CC[C@@H]1C(=O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P23 compound treatment 116240.0 -17900.0 -0.55 116440.0 -19000.0 -0.49 -0.7404 -0.9983 3559434 ACon1_002239 CCCCCCCCCCCC=C=CCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2296 P24 compound treatment 102120.0 -32000.0 -0.99 81480.0 -53900.0 -1.4 -1.6921 -0.9857 3559647 ACon1_002240 COc1ccc2C(=O)/C(=C/c3ccccc3)/Oc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A01 compound treatment 8200.0 -121000.0 -3.74 7200.0 -124000.0 -3.23 -4.9299 -0.9974 3552712 ACon1_002241 C[C@@H]1CCC/C=C/[C@H]2C[C@@H](O)C[C@@H]2[C@@H](O)/C=C/C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A02 compound treatment 107320.0 -21500.0 -0.67 103480.0 -28200.0 -0.73 -0.9894 -0.9989 3559403 ACon1_002242 O=CNCCc1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A03 compound treatment 156720.0 27900.0 0.86 155000.0 23300.0 0.61 1.0395 0.985 1060832 ACon1_002243 OCC(Cc1ccccc1)NC(=O)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A04 compound treatment 194000.0 65200.0 2.02 172200.0 40500.0 1.05 2.1723 0.954 3555658 ACon1_002244 O=C(N[C@H](COC(=O)[C@H](Cc1ccccc1)NC(=O)c2ccccc2)Cc3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A05 compound treatment 192480.0 63600.0 1.97 140560.0 8900.0 0.23 1.5577 0.7847 3554875 ACon1_002245 COc1cc(ccc1O)[C@H]2[C@H]3COC4(O)[C@H]3C(=CC2C4=O)[C@H]5Oc6cc(O)cc(O)c6C(=O)[C@@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A06 compound treatment 8840.0 -120000.0 -3.72 6880.0 -125000.0 -3.24 -4.9218 -0.9977 1032994 ACon1_002246 O=C1CC(Oc2ccccc12)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A07 compound treatment 37480.0 -91400.0 -2.83 12320.0 -119000.0 -3.1 -4.1944 -0.999 3559373 ACon1_002247 C/C=C(\C)/C(=O)O[C@@H]1[C@H](OC(=O)C)[C@@H](C)[C@](C)(CC(=O)c2ccoc2)C3CCC=C(C)[C@]13C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A08 compound treatment 173680.0 44800.0 1.39 89680.0 -42000.0 -1.09 0.211 0.1195 3557592 ACon1_002248 CC1(C)CCCC2(C)C(CCC(=C)C(O)CO)C(C)(O)CCC12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A09 compound treatment 73400.0 -55400.0 -1.72 51040.0 -80600.0 -2.09 -2.696 -0.9952 3559707 ACon1_002249 COc1ccc2C=C(COc2c1)c3cc(O)c(O)cc3OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A10 compound treatment 155160.0 26300.0 0.82 76440.0 -55200.0 -1.43 -0.438 -0.2654 3559278 ACon1_002250 CC1=CC(=O)C[C@]2(C)CC[C@H](CC12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A11 compound treatment 118840.0 -10000.0 -0.31 89520.0 -42100.0 -1.09 -0.9934 -0.873 3559492 ACon1_002251 C[C@@H]1CCC2C(=CC(=O)CC2(C)C)[C@@]1(C)CC/C(=C/CO)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A12 compound treatment 194040.0 65200.0 2.02 123920.0 -7740.0 -0.2 1.2862 0.6336 3616487 ACon1_002252 CC1OC(=O)CC2C(=CC3CC(C)(C)CC321)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A13 mock treatment 193560.0 64700.0 2.01 149440.0 17800.0 0.46 1.7445 0.8478 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A14 mock treatment 191400.0 62600.0 1.94 157520.0 25900.0 0.67 1.8456 0.8997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A15 compound treatment 114400.0 -14400.0 -0.45 88560.0 -43100.0 -1.12 -1.1084 -0.919 3616488 ACon1_002253 CON1c2ccccc2[C@]3(C=C(OC)C(=O)N4/C(=C/c5cnc[nH]5)/C(=O)N[C@@]143)C(C)(C)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A16 compound treatment 218400.0 89600.0 2.77 150240.0 18600.0 0.48 2.3034 0.8178 1637425 ACon1_002254 Cc1cc(O)c(Cc2c(O)cc(C)oc2=O)c(=O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A17 compound treatment 202200.0 73400.0 2.27 147800.0 16100.0 0.42 1.9037 0.8237 3558320 ACon1_002255 COc1cc(/C=C/C(=O)NCCCCNC(=O)C)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A18 compound treatment 200640.0 71800.0 2.22 148920.0 17300.0 0.45 1.8901 0.8329 3553473 ACon1_002256 CC(C)(O)C1=CCC2(COC3C2)C1CCC3(O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A19 compound treatment 204240.0 75400.0 2.34 148000.0 16300.0 0.42 1.952 0.8222 3558714 ACon1_002257 COc1cc(O)c2c(=O)c(O[C@@H]3O[C@@H](CO)[C@H](O)[C@H]3O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)c(oc2c1)c5ccc(O)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A20 compound treatment 10760.0 -118000.0 -3.66 8080.0 -124000.0 -3.21 -4.8577 -0.9979 3616491 ACon1_002258 COc1cc(oc(=O)c1C)/C(=C/C(=C\C(=O)O)/C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A21 compound treatment 132160.0 3310.0 0.1 140280.0 8620.0 0.22 0.231 0.9375 3559881 ACon1_002259 CC(=CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)C[C@H](Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A22 compound treatment 103640.0 -25200.0 -0.78 93320.0 -38300.0 -1.0 -1.2567 -0.9927 3616494 ACon1_002260 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@H]3[C@H](O)[C@@H](CO)O[C@@H](O[C@H]4CC[C@@]5(C)C(CC[C@]6(C)C5C=C[C@@]78OC[C@@]9(CCC(C)(C)C[C@H]98)[C@@H](O)C[C@]76C)[C@]4(C)CO)[C@@H]3O[C@@H]%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A23 compound treatment 106520.0 -22300.0 -0.69 131000.0 -660.0 -0.02 -0.5013 -0.7244 3552806 ACon1_002261 C[C@@H]1O[C@@H](OCC2OC(O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC[C@@H]6C7[C@@](C)(O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@@H](CC=C(C)C)O[C@@]7(O)[C@H](O)[C@]65C)C3(C)C)C(O)C(O)C2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 A24 compound treatment 75560.0 -53300.0 -1.65 88280.0 -43400.0 -1.13 -1.9645 -0.9827 1062887 ACon1_002262 CC1C(=O)c2cc3OCOc3cc2CCN(C)Cc4c5OCOc5ccc14 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B01 compound treatment 130520.0 1670.0 0.05 122520.0 -9140.0 -0.24 -0.1312 -0.5399 1047225 ACon1_002263 COC1C(O)CC2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC2C1C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B02 mock treatment 161880.0 33000.0 1.02 155240.0 23600.0 0.61 1.157 0.9699 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B03 compound treatment 147800.0 19000.0 0.59 119120.0 -12500.0 -0.33 0.1849 0.2753 3559335 ACon1_002264 COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)/C(=C\C)/C1CC(=O)OCC(CO)C3CC(OC(=O)CC4\C(=C\C)\C(OC5OC(CO)C(O)C(O)C5O)OC=C4C(=O)OC)C(C)C3COC(=O)CC6\C(=C\C)\C(OC7OC(CO)C(O)C(O)C7O)OC=C6C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B04 mock treatment 135440.0 6590.0 0.2 150080.0 18400.0 0.48 0.4829 0.9279 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B05 compound treatment 127720.0 -1130.0 -0.03 183960.0 52300.0 1.36 0.9362 0.6887 3616499 ACon1_002265 CO[C@@H]1[C@H](Oc2c(CC=C(C)C)c(O)c(CC=C(C)C)c(O)c2C1=O)c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B06 mock treatment 186800.0 58000.0 1.8 169640.0 38000.0 0.99 1.9675 0.9603 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B07 compound treatment 102760.0 -26100.0 -0.81 61200.0 -70500.0 -1.83 -1.8661 -0.9325 3616501 ACon1_002266 O[C@H]1[C@@H](C[C@@](O)(C[C@H]1OC(=O)/C=C/c2ccc(O)cc2)C(=O)O)OC(=O)/C=C/c3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B08 mock treatment 142160.0 13300.0 0.41 135440.0 3780.0 0.1 0.3612 0.8517 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B09 compound treatment 190920.0 62100.0 1.92 133840.0 2180.0 0.06 1.4001 0.7276 3616503 ACon1_002267 COC(=O)[C@]12O[C@@H]2[C@@H](C[C@H]3[C@]4(C)C[C@H](OC(=O)[C@H]4CC[C@]31C)c5ccoc5)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B10 mock treatment 118080.0 -10800.0 -0.33 156560.0 24900.0 0.65 0.2216 0.3044 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B11 compound treatment 129160.0 314.0 0.01 140200.0 8540.0 0.22 0.1638 0.7374 3616506 ACon1_002268 OC1C(O)C2C(C(C1C=C2/C=C/C(=O)O)c3ccc(O)c(O)c3)C(=O)OC(Cc4ccc(O)c(O)c4)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B12 mock treatment 129880.0 1030.0 0.03 199960.0 68300.0 1.77 1.2775 0.7198 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B13 mock treatment 150720.0 21900.0 0.68 169960.0 38300.0 1.0 1.1829 0.9825 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B14 mock treatment 140160.0 11300.0 0.35 193080.0 61400.0 1.6 1.3763 0.8424 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B15 compound treatment 187640.0 58800.0 1.82 152640.0 21000.0 0.55 1.6736 0.8801 3558465 ACon1_002269 CC1OC(OC2C(O)C(O)C(CO)OC2Oc3c(oc4cc(OC5OC(C)C(O)C(O)C5O)cc(O)c4c3=O)c6ccc(O)cc6)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B16 mock treatment 151840.0 23000.0 0.71 146760.0 15100.0 0.39 0.7812 0.9605 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B17 compound treatment 199800.0 71000.0 2.2 168760.0 37100.0 0.96 2.2362 0.9315 3555288 ACon1_002270 COc1ccc2CC3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2C54CCN3C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B18 mock treatment 172440.0 43600.0 1.35 152720.0 21100.0 0.55 1.342 0.9209 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B19 compound treatment 216080.0 87200.0 2.7 155120.0 23500.0 0.61 2.3423 0.8453 3559140 ACon1_002271 C/C=C(/C)\C(=O)O[C@H]1CC(C)(C)C[C@H]2C3=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H](O)[C@H]6O[C@@H]9O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O)C(=O)O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)[C@@H](O)[C@@H](O)[C@@]12CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B20 mock treatment 187360.0 58500.0 1.81 163280.0 31600.0 0.82 1.8629 0.9359 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B21 compound treatment 11200.0 -118000.0 -3.65 10480.0 -121000.0 -3.15 -4.8039 -0.9973 3559603 ACon1_002272 CC1(C)CCCC2C3(C)CCC(C)(CC3CCC21O)C(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B22 mock treatment 170760.0 41900.0 1.3 177560.0 45900.0 1.19 1.7616 0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B23 compound treatment 125840.0 -3010.0 -0.09 118760.0 -12900.0 -0.34 -0.3029 -0.8706 3558670 ACon1_002273 Oc1ccc2c(cc3NC(=O)c4cc5OCOc5c2c34)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 B24 mock treatment 124680.0 -4170.0 -0.13 124960.0 -6700.0 -0.17 -0.2144 -0.9892 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C01 compound treatment 114680.0 -14200.0 -0.44 82600.0 -49100.0 -1.27 -1.2117 -0.8988 3557715 ACon1_002274 OC[C@H]1O[C@@H](O[C@H](CCCCc2ccc(O)c(O)c2)CCc3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C02 compound treatment 10200.0 -119000.0 -3.68 8800.0 -123000.0 -3.19 -4.8567 -0.9975 3559945 ACon1_002275 OC[C@H]1O[C@@H](OC(C#N)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C03 compound treatment 153320.0 24500.0 0.76 125520.0 -6140.0 -0.16 0.4234 0.5464 3558659 ACon1_002276 CC(C)(O)c1ccc2c(CCC3C(C)(CCCC32C)C(=O)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C04 compound treatment 148800.0 20000.0 0.62 115400.0 -16300.0 -0.42 0.1384 0.1849 3553732 ACon1_002277 CC(NC(=O)/C=C/C(=O)O)C(=O)NC(C(C)c1c[nH]c2ccccc12)C(=O)NC(Cc3c[nH]c4ccccc34)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C05 compound treatment 45560.0 -83300.0 -2.58 24960.0 -107000.0 -2.77 -3.7851 -0.9994 3553321 ACon1_002278 CC(=O)O[C@@H]/1C\C=C(/C)\C[C@@H](OC(=O)/C(=C/CO)/CO)C2[C@H](OC(=O)C2=C)/C=C1/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C06 compound treatment 118960.0 -9890.0 -0.31 190640.0 59000.0 1.53 0.867 0.5548 3616509 ACon1_002279 CC1=C[C@H](O)[C@H]2C(C)(C)CCC[C@]2(C)[C@@]1(O)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C07 compound treatment 138880.0 10000.0 0.31 122440.0 -9220.0 -0.24 0.0504 0.1285 3554995 ACon1_002280 COc1cc(O)cc2cc3OC(C)(O)CC(=O)c3c(O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C08 compound treatment 57280.0 -71600.0 -2.22 40280.0 -91400.0 -2.37 -3.2469 -0.9994 3554703 ACon1_002281 COC(=O)c1cc(O)cc(O)c1C(=O)c2c(O)cc(C)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C09 compound treatment 127240.0 -1610.0 -0.05 96480.0 -35200.0 -0.91 -0.6815 -0.7445 3559543 ACon1_002282 C[C@]12C[C@H]3OC(=O)C(=C)[C@H]3CC2C(=C)CC[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C10 compound treatment 124880.0 -3970.0 -0.12 98760.0 -32900.0 -0.85 -0.6914 -0.8005 2107842 ACon1_002283 C[C@H]1C[C@@]2(O)[C@H]([C@H]1OC(=O)c3ccccc3)[C@@H](OC(=O)COC(=O)C)[C@]4(C[C@@H]5[C@H](CC(C)(C)C5=O)[C@](C)(C4OC(=O)C)[C@H]2OC(=O)C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C11 mock treatment 117480.0 -11400.0 -0.35 169880.0 38200.0 0.99 0.4532 0.4301 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C12 mock treatment 114960.0 -13900.0 -0.43 157560.0 25900.0 0.67 0.1716 0.2149 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C13 compound treatment 144560.0 15700.0 0.49 129000.0 -2660.0 -0.07 0.2954 0.6007 3554771 ACon1_002284 COc1c(O)ccc2C([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c4cc(C)cc(O)c4C(=O)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C14 compound treatment 155920.0 27100.0 0.84 179480.0 47800.0 1.24 1.4718 0.9817 3616510 ACon1_002285 CC1CC(=O)C2=C(O1)OC3(C)CCC4(O)C(C)(C)C=CC(=O)C4(C)C3C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C15 mock treatment 179320.0 50500.0 1.56 154520.0 22900.0 0.59 1.5259 0.9121 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C16 mock treatment 133000.0 4150.0 0.13 154840.0 23200.0 0.6 0.5169 0.8393 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C17 compound treatment 160480.0 31600.0 0.98 109000.0 -22700.0 -0.59 0.2768 0.242 3558911 ACon1_002286 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)[C@@H]2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C18 compound treatment 14200.0 -115000.0 -3.55 11240.0 -120000.0 -3.13 -4.7242 -0.998 3559669 ACon1_002287 COC(=O)C1(C)CCCC(=C)C1CC/C(=C/CCC2=CC(=O)OC2)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C19 compound treatment 168920.0 40100.0 1.24 150880.0 19200.0 0.5 1.2311 0.9199 3555826 ACon1_002288 OC(=O)C1OC(=O)C(CCCCCCCCC=C)C1(O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C20 compound treatment 138520.0 9670.0 0.3 115720.0 -15900.0 -0.41 -0.0809 -0.1583 3616511 ACon1_002289 COc1ccc(/C=C/C(=O)O[C@H]2[C@H](C)O[C@@H](O[C@@H]3C=C(CO)[C@@H]4[C@H]3C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H]2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C21 compound treatment 173760.0 44900.0 1.39 149760.0 18100.0 0.47 1.3166 0.8963 3616514 ACon1_002290 O[C@H]1[C@@H](C[C@@](O)(C[C@H]1OC(=O)/C=C/c2ccc(O)c(O)c2)C(=O)O)OC(=O)/C=C/c3ccc(O)c(O)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C22 compound treatment 139640.0 10800.0 0.33 134880.0 3220.0 0.08 0.2957 0.8576 3616517 ACon1_002291 COC(=O)CC1(C/C=C(\C)/CCC=C(C)C)CC(=O)CCC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C23 compound treatment 150280.0 21400.0 0.66 123440.0 -8220.0 -0.21 0.3186 0.4567 3555607 ACon1_002292 O[C@@H]1Cc2c(O)cc3O[C@]4(Oc5cc(O)cc(O)c5[C@H]([C@H]4O)c3c2O[C@@H]1c6ccc(O)cc6)c7ccc(O)cc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 C24 compound treatment 126040.0 -2810.0 -0.09 131840.0 180.0 0.0 -0.0582 -0.6681 3069520 ACon1_002293 COc1ccc2CC3N(CCc4cc(OC)c(O)cc34)Cc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D01 compound treatment 146600.0 17800.0 0.55 97320.0 -34300.0 -0.89 -0.2419 -0.2308 3616522 ACon1_002294 C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3C=C[C@@]56OC[C@@]7(CCC(C)(C)C[C@H]76)[C@@H](O)C[C@]54C)[C@]2(C)CO)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O[C@@H]9O[C@H](CO)[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D02 mock treatment 186280.0 57400.0 1.78 141600.0 9940.0 0.26 1.441 0.8013 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D03 compound treatment 160840.0 32000.0 0.99 131640.0 -20.0 0.0 0.7006 0.7067 3616525 ACon1_002295 OC[C@H]1O[C@@H](Oc2ccc3[C@@H]4Oc5cc6OCOc6cc5[C@@H]4COc3c2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D04 mock treatment 134760.0 5910.0 0.18 155280.0 23600.0 0.61 0.5635 0.8799 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D05 compound treatment 129200.0 354.0 0.01 118560.0 -13100.0 -0.34 -0.2329 -0.684 3616527 ACon1_002296 COC(=O)C1=C[C@@H](C[C@H]2[C@]3(C)C[C@H](OC(=O)[C@H]3CC[C@]21C)c4ccoc4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D06 mock treatment 135280.0 6430.0 0.2 179560.0 47900.0 1.24 1.021 0.81 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D07 compound treatment 121200.0 -7650.0 -0.24 137600.0 5940.0 0.15 -0.0584 -0.2065 3616529 ACon1_002297 CC1OC(OC2C(O)COC(OC3C(O)C(C)OC(OC4C(OC(=O)C56CCC(C)(C)CC6C7=CCC8C9(C)CC(O)C(OC%10OC(C)C(O)C(OC%11OCC(O)C(OC%12OCC(OC%13OCC(O)(CO)C%13O)C(O)C%12O)C%11O)C%10O)C(C)(CO)C9CCC8(C)C7(C)CC5O)OC(C)C(O)C4OC%14OCC(O)C(O)C%14O)C3O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D08 mock treatment 125640.0 -3210.0 -0.1 140480.0 8820.0 0.23 0.0918 0.3676 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D09 compound treatment 111840.0 -17000.0 -0.53 69440.0 -62200.0 -1.62 -1.5157 -0.8914 3616530 ACon1_002298 CC(C)(O)CCc1cc2[C@@H]3COc4cc(O)ccc4[C@@H]3Oc2cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D10 mock treatment 116600.0 -12200.0 -0.38 149320.0 17700.0 0.46 0.0562 0.0943 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D11 mock treatment 123600.0 -5250.0 -0.16 129320.0 -2340.0 -0.06 -0.1579 -0.91 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D12 mock treatment 107080.0 -21800.0 -0.67 135360.0 3700.0 0.1 -0.4089 -0.6002 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D13 compound treatment 126720.0 -2130.0 -0.07 134440.0 2780.0 0.07 0.0045 0.046 3616533 ACon1_002299 CC1(CO)C(OC2OCC(O)C(O)C2OC3OC(CO)C(O)C(O)C3O)C(O)CC4(C)C1CCC5(C)C4CC=C6C7CC(=C)CCC7(CCC65C)C(=O)OC8OC(CO)C(O)C(O)C8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D14 mock treatment 132920.0 4070.0 0.13 136480.0 4820.0 0.13 0.1778 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D15 mock treatment 121520.0 -7330.0 -0.23 133440.0 1780.0 0.05 -0.1278 -0.5517 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D16 mock treatment 117840.0 -11000.0 -0.34 134040.0 2380.0 0.06 -0.1974 -0.5696 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D17 compound treatment 115280.0 -13600.0 -0.42 96880.0 -34800.0 -0.9 -0.9362 -0.9394 3559611 ACon1_002300 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O[C@H]5CC[C@@]6(C)C(CC[C@]7(C)C6CC[C@@]89OC[C@@]%10(CCC(C)(C)CC%109)[C@H](O)C[C@]87C)C5(C)C)O[C@@H]3C(=O)O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D18 mock treatment 140320.0 11500.0 0.36 142200.0 10500.0 0.27 0.445 0.9917 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D19 compound treatment 177760.0 48900.0 1.52 143800.0 12100.0 0.32 1.2947 0.8364 3559413 ACon1_002301 COC(=O)[C@H]1CC[C@H](OC(=O)C)[C@]2(C)CC[C@@H](C(C)C)[C@@H](OC(=O)/C=C/c3ccccc3)C12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D20 mock treatment 130720.0 1870.0 0.06 144800.0 13100.0 0.34 0.2825 0.8157 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D21 compound treatment 133520.0 4670.0 0.14 118880.0 -12800.0 -0.33 -0.1324 -0.3655 3559708 ACon1_002302 CC(OC(=O)/C=C(/C)\COC(=O)C)c1ccc(O)c(c1)C(=O)C=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D22 mock treatment 134640.0 5790.0 0.18 137320.0 5660.0 0.15 0.2309 0.9951 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D23 compound treatment 128240.0 -606.0 -0.02 113800.0 -17900.0 -0.46 -0.3414 -0.7351 3558805 ACon1_002303 CC1[C@@H]2CCC3(C)OC43C(O)C=C(C)C4[C@H]2OC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 D24 mock treatment 125040.0 -3810.0 -0.12 121440.0 -10200.0 -0.27 -0.2712 -0.9332 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E01 mock treatment 137800.0 8950.0 0.28 113160.0 -18500.0 -0.48 -0.1437 -0.2589 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E02 mock treatment 133760.0 4910.0 0.15 144600.0 12900.0 0.34 0.3454 0.9358 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E03 compound treatment 17360.0 -111000.0 -3.45 14720.0 -117000.0 -3.04 -4.5911 -0.998 3616539 ACon1_002304 COc1cccc2C(=O)c3c(C(=O)c12)c(O)cc4CC(C)(O)CC(=O)c43 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E04 compound treatment 115600.0 -13200.0 -0.41 128160.0 -3500.0 -0.09 -0.3545 -0.8433 3616542 ACon1_002305 CC(O)/C=C/C1(O)C(C)CC(O)CC1(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E05 compound treatment 133840.0 4990.0 0.15 131560.0 -100.0 0.0 0.1076 0.6951 1054502 ACon1_002306 COc1cc2n(C)c3ccccc3c(=O)c2c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E06 compound treatment 106200.0 -22600.0 -0.7 97000.0 -34700.0 -0.9 -1.133 -0.9924 3616546 ACon1_002307 CC1OC(OCC2(C)CCC3(CCC4(C)C(CCC5C6(C)CCC(O)C(C)(COC7OC(CO)C(O)C(O)C7O)C6CCC54C)C3=C2)C(=O)O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E07 compound treatment 120160.0 -8690.0 -0.27 126560.0 -5100.0 -0.13 -0.284 -0.9467 3616548 ACon1_002308 CC(O)CC1CCC(O)C(C)C(=O)OC(CC(C)O)CCC(O)C(C)C(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E08 compound treatment 130200.0 1350.0 0.04 131600.0 -60.0 0.0 0.0286 0.6804 3559871 ACon1_002309 C/C=C\1/CN2C3Cc4c([nH]c5ccc(O)cc45)C2(O)CC1C3CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E09 mock treatment 127360.0 -1490.0 -0.05 129000.0 -2660.0 -0.07 -0.0814 -0.9805 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E10 mock treatment 123000.0 -5850.0 -0.18 133120.0 1460.0 0.04 -0.1013 -0.5471 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E11 compound treatment 111720.0 -17100.0 -0.53 132480.0 820.0 0.02 -0.3602 -0.6782 3559551 ACon1_002310 C[C@H]1C[C@H]2OC(=O)C(=C2CC/C(=C/CC1=O)/C)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E12 compound treatment 129120.0 274.0 0.01 122120.0 -9540.0 -0.25 -0.1693 -0.6825 3616552 ACon1_002311 CC1CCC2C(=CC3(O)CC(C)(C)CC123)C(=O)OC4OC(C)C(O)C(O)C4O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E13 compound treatment 128280.0 -566.0 -0.02 133320.0 1660.0 0.04 0.0181 0.3887 3420076 ACon1_002312 CC1CC(C)C(=O)C(C1)C(O)CC2CC(=O)NC(=O)C2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E14 compound treatment 14080.0 -115000.0 -3.56 14000.0 -118000.0 -3.06 -4.6762 -0.9972 3559755 ACon1_002313 CC1(CCCC(C)(C)C2C3CCC21)C3CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E15 compound treatment 125880.0 -2970.0 -0.09 115680.0 -16000.0 -0.42 -0.3586 -0.8432 3554678 ACon1_002314 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\C)/[C@@H]1CC(=O)OC[C@H]3O[C@@H](OCCc4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]3OC(=O)C[C@H]5\C(=C\C)\[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)OC=C5C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E16 compound treatment 138000.0 9150.0 0.28 124720.0 -6940.0 -0.18 0.0731 0.2174 3559326 ACon1_002315 CC(=CCC/C(=C/CC(O)/C(=C/Cc1cc(ccc1O)C(=O)O)/C)/C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E17 mock treatment 128080.0 -766.0 -0.02 136320.0 4660.0 0.12 0.0688 0.5579 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E18 mock treatment 122200.0 -6650.0 -0.21 133080.0 1420.0 0.04 -0.1195 -0.5713 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E19 compound treatment 142640.0 13800.0 0.43 132000.0 340.0 0.01 0.3085 0.7216 3553717 ACon1_002316 CC(CCCCC(O)C(CO)C(=O)OC(CCCCC(C)C/C(=C/C(=C/C(=O)O)/C)/C)C(CO)C(=O)O)C/C(=C/C(=C/C(=O)O)/C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E20 compound treatment 112320.0 -16500.0 -0.51 116560.0 -15100.0 -0.39 -0.6395 -0.9914 3616556 ACon1_002317 O=C(NCCCCNCCCNC(=O)/C=C/c1ccccc1)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E21 compound treatment 138520.0 9670.0 0.3 137880.0 6220.0 0.16 0.3262 0.958 3554770 ACon1_002318 COc1c(O)cc2C(Oc3cc4C(O)C(C)OC(=O)c4c(O)c3OC)C(C)OC(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E22 compound treatment 130960.0 2110.0 0.07 124680.0 -6980.0 -0.18 -0.0819 -0.4249 3616560 ACon1_002319 O[C@@H]1[C@@H](COC(=O)/C=C/C2(O)C=CC(=O)C=C2)O[C@@H](Oc3ccc(O)cc3)[C@H](O)[C@H]1OC(=O)/C=C/C4(O)C=CC(=O)C=C4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E23 compound treatment 32440.0 -96400.0 -2.99 29760.0 -102000.0 -2.65 -3.9844 -0.9982 1088382 ACon1_002320 CCC(C)C1NC(=O)C2CCCN2C(=O)C(CC(C)C)OC(=O)CCNC(=O)C(C)N(C)C(=O)C(C(C)C)N(C)C1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 E24 compound treatment 22400.0 -106000.0 -3.3 18440.0 -113000.0 -2.94 -4.4123 -0.9984 3616565 ACon1_002321 OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F01 mock treatment 159560.0 30700.0 0.95 125200.0 -6460.0 -0.17 0.5542 0.5735 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F02 mock treatment 148360.0 19500.0 0.6 132360.0 700.0 0.02 0.4404 0.728 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F03 compound treatment 149480.0 20600.0 0.64 138520.0 6860.0 0.18 0.5781 0.871 3212153 ACon1_002322 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F04 mock treatment 134160.0 5310.0 0.16 145880.0 14200.0 0.37 0.3777 0.9337 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F05 compound treatment 139960.0 11100.0 0.34 134160.0 2500.0 0.06 0.2894 0.8259 3616570 ACon1_002323 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H]4CN5CCc6c([nH]c7ccccc67)[C@]5(C[C@@H]31)O4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F06 mock treatment 117800.0 -11000.0 -0.34 132400.0 740.0 0.02 -0.2284 -0.6663 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F07 compound treatment 103640.0 -25200.0 -0.78 124160.0 -7500.0 -0.19 -0.69 -0.8573 3616572 ACon1_002324 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](COC3OCC(O)C(O)C3O)O[C@@H](Oc4cc(O)c5C(=O)CC(Oc5c4)c6ccc(O)cc6)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F08 mock treatment 119880.0 -8970.0 -0.28 141800.0 10100.0 0.26 -0.0101 -0.0265 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F09 mock treatment 113480.0 -15400.0 -0.48 130840.0 -820.0 -0.02 -0.3517 -0.738 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F10 mock treatment 118280.0 -10600.0 -0.33 125440.0 -6220.0 -0.16 -0.3458 -0.9471 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F11 compound treatment 126000.0 -2850.0 -0.09 129080.0 -2580.0 -0.07 -0.1098 -0.9908 3616576 ACon1_002325 CC(=CCc1cc2C(=O)C(O)C(Oc2c3C(O)C(O)C(C)(C)Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F12 mock treatment 115600.0 -13200.0 -0.41 131800.0 140.0 0.0 -0.2876 -0.7008 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F13 compound treatment 100800.0 -28000.0 -0.87 122200.0 -9460.0 -0.25 -0.7883 -0.8729 3616580 ACon1_002326 COc1cc(CC2COC(C2COC3OC(CO)C(O)C(O)C3O)c4ccc(O)c(OC)c4)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F14 mock treatment 124320.0 -4530.0 -0.14 135000.0 3340.0 0.09 -0.0378 -0.2292 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F15 compound treatment 140640.0 11800.0 0.37 127640.0 -4020.0 -0.1 0.1845 0.4856 2090754 ACon1_002327 COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F16 mock treatment 132040.0 3190.0 0.1 132320.0 660.0 0.02 0.0821 0.8175 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F17 mock treatment 116680.0 -12200.0 -0.38 132040.0 380.0 0.01 -0.2596 -0.6883 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F18 mock treatment 121000.0 -7850.0 -0.24 132680.0 1020.0 0.03 -0.1532 -0.6263 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F19 compound treatment 148840.0 20000.0 0.62 148040.0 16400.0 0.43 0.739 0.9832 3559435 ACon1_002328 COc1c2occc2c(OCC(OC(=O)/C(=C\C)/C)C(C)(C)O)c3ccc(=O)oc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F20 mock treatment 128400.0 -446.0 -0.01 129480.0 -2180.0 -0.06 -0.0498 -0.8545 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F21 compound treatment 115880.0 -13000.0 -0.4 86200.0 -45500.0 -1.18 -1.1193 -0.8971 3558554 ACon1_002329 CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@H]7OC[C@](O)(CO)[C@H]7O)[C@H](O)[C@H]6O)C(=O)O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F22 mock treatment 156760.0 27900.0 0.86 135840.0 4180.0 0.11 0.6884 0.7897 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F23 compound treatment 93640.0 -35200.0 -1.09 92360.0 -39300.0 -1.02 -1.4934 -0.9995 3616583 ACon1_002330 OC(=O)c1cc(O)c(O)c(O)c1Oc2cc3C(=O)OC[C@H]4O[C@@H](OC(=O)c5cc(O)c(O)c(O)c5)[C@H](OC(=O)c6cc(O)c(O)c(O)c6)[C@@H](OC(=O)c7cc(O)c(O)c(O)c7)[C@@H]4OC(=O)c8cc(O)c(O)c(O)c8-c3c(O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 F24 mock treatment 136000.0 7150.0 0.22 98120.0 -33500.0 -0.87 -0.4595 -0.511 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G01 compound treatment 122200.0 -6650.0 -0.21 116800.0 -14900.0 -0.39 -0.4186 -0.9567 3557489 ACon1_002331 CC12CC3(CC2C1CC34)CC(O)C5C(C)(CO)CCCC45C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G02 compound treatment 119880.0 -8970.0 -0.28 113720.0 -17900.0 -0.47 -0.526 -0.9694 3557405 ACon1_002332 CCCC(O)C(O)C1CC(=CC(=O)O1)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G03 mock treatment 129440.0 594.0 0.02 146840.0 15200.0 0.39 0.2919 0.7393 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G04 mock treatment 126480.0 -2370.0 -0.07 134920.0 3260.0 0.08 0.0081 0.0719 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G05 compound treatment 110360.0 -18500.0 -0.57 97720.0 -33900.0 -0.88 -1.0286 -0.9782 3554767 ACon1_002333 COc1c(O)c2c(CCC3C(C)(C)CCC[C@@]32C(=O)O)cc1C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G06 compound treatment 145400.0 16600.0 0.51 120120.0 -11500.0 -0.3 0.1507 0.2536 3616588 ACon1_002334 COC(=O)c1cc(C)cc(O)c1C(=O)c2c(O)cccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G07 compound treatment 138520.0 9670.0 0.3 146760.0 15100.0 0.39 0.4894 0.9912 1034509 ACon1_002335 Cc1cc(=O)c2COc3cc(O)c(O)c(C(=O)O)c3-c2o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G08 compound treatment 95320.0 -33500.0 -1.04 94960.0 -36700.0 -0.95 -1.4088 -0.9991 3552648 ACon1_002336 C[C@@H]1C[C@H](O)/C=C/[C@H](O)[C@@H](O)CC(=O)O1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G09 compound treatment 128080.0 -766.0 -0.02 129480.0 -2180.0 -0.06 -0.0568 -0.9254 3557256 ACon1_002337 CC(=O)c1c(O)cc(O)cc1CC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G10 compound treatment 63040.0 -65800.0 -2.04 79720.0 -51900.0 -1.35 -2.396 -0.9799 3555790 ACon1_002338 O=C1NC(Cc2c[nH]c3ccccc23)C(=O)N4CCCC41 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G11 compound treatment 126320.0 -2530.0 -0.08 116040.0 -15600.0 -0.41 -0.3423 -0.8282 3616592 ACon1_002339 CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(CO)CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G12 compound treatment 143800.0 15000.0 0.46 157960.0 26300.0 0.68 0.8108 0.9821 3616597 ACon1_002340 CCCC1(O)Cc2c(O1)c3c(O)cccc3cc2C(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G13 compound treatment 124040.0 -4810.0 -0.15 136800.0 5140.0 0.13 -0.0109 -0.0543 3558181 ACon1_002341 COc1cc(ccc1O)C2OCC3C(OC(=O)C23)c4ccc5OCOc5c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G14 compound treatment 130640.0 1790.0 0.06 133160.0 1500.0 0.04 0.0669 0.9849 1029487 ACon1_002342 OCC(O)Cc1ccc2OCOc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G15 compound treatment 129520.0 674.0 0.02 129960.0 -1700.0 -0.04 -0.0165 -0.337 3553721 ACon1_002343 CC(CCCCCC(O)C(CO)C(=O)O)C/C(=C/C(=C/C(=O)O)/C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G16 compound treatment 151120.0 22300.0 0.69 161360.0 29700.0 0.77 1.0337 0.9984 3554667 ACon1_002344 COC(=O)C1(CO)C2Cc3c(C4CC1/C(=C\C)/CN42)n(C)c5ccccc35 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G17 compound treatment 126720.0 -2130.0 -0.07 133840.0 2180.0 0.06 -0.0065 -0.0751 3558054 ACon1_002345 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C\CO)/[C@@H]1CC(=O)OCCc3ccc(O)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G18 compound treatment 127680.0 -1170.0 -0.04 130000.0 -1660.0 -0.04 -0.056 -0.9961 3553083 ACon1_002346 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5CC(CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H]6O[C@@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)N9C[C@@H](C)CC[C@H]19 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G19 mock treatment 144000.0 15200.0 0.47 137400.0 5740.0 0.15 0.4375 0.888 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G20 mock treatment 130840.0 1990.0 0.06 133200.0 1540.0 0.04 0.072 0.9779 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G21 compound treatment 139000.0 10200.0 0.31 151400.0 19700.0 0.51 0.5851 0.9725 3557521 ACon1_002347 COc1cc(/C=C/C(=O)OC2C(O)C(O)C(OC3(CO)OC(CO)C(O)C3O)OC2COC(=O)c4cc(OC)c(OC)c(OC)c4)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G22 compound treatment 101040.0 -27800.0 -0.86 93520.0 -38100.0 -0.99 -1.3099 -0.9976 3557725 ACon1_002348 OC[C@H]1OC(Oc2cc(O)c3c(=O)c(O)c(oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G23 compound treatment 129440.0 594.0 0.02 124640.0 -7020.0 -0.18 -0.116 -0.6325 3558206 ACon1_002349 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H](O)[C@H]1OC(=O)/C=C/c6ccc(O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 G24 compound treatment 73040.0 -55800.0 -1.73 93120.0 -38500.0 -1.0 -1.9308 -0.9663 1011276 ACon1_002350 COc1ccc2CC3N(C)CCc4cc5OCOc5c(c34)-c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H01 compound treatment 115800.0 -13000.0 -0.4 121120.0 -10500.0 -0.27 -0.4795 -0.982 3616603 ACon1_002351 O[C@H]1[C@H](O)[C@@H](COC(=O)CC(=O)O)O[C@@H](Oc2ccc3[C@@H]4Oc5cc6OCOc6cc5[C@@H]4COc3c2)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H02 mock treatment 157280.0 28400.0 0.88 145920.0 14300.0 0.37 0.885 0.9259 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H03 mock treatment 143720.0 14900.0 0.46 153000.0 21300.0 0.55 0.718 0.9958 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H04 mock treatment 153400.0 24600.0 0.76 159560.0 27900.0 0.72 1.0506 0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H05 compound treatment 147000.0 18200.0 0.56 163000.0 31300.0 0.81 0.9735 0.9837 3616608 ACon1_002352 COC(=O)C1=CC(=C[C@H]2[C@]3(C)C[C@H](OC(=O)[C@H]3CC[C@]21C)c4ccoc4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H06 mock treatment 147200.0 18400.0 0.57 137000.0 5340.0 0.14 0.5002 0.8546 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H07 compound treatment 156840.0 28000.0 0.87 168600.0 36900.0 0.96 1.292 0.9987 3616611 ACon1_002353 CC(C)(CCO[C@@H]1O[C@H](CO[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)C[C@@H]3C(=CC[C@]4(C(=O)O)C3=CCC5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)C6CC[C@]54C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H08 mock treatment 144800.0 16000.0 0.49 163440.0 31800.0 0.83 0.9334 0.9699 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H09 compound treatment 146080.0 17200.0 0.53 144440.0 12800.0 0.33 0.6124 0.9739 3616613 ACon1_002354 Oc1ccccc1Cc2c(O)cc(O)c3C(=O)C[C@@H](Oc23)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H10 mock treatment 137920.0 9070.0 0.28 129560.0 -2100.0 -0.05 0.1602 0.5594 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H11 compound treatment 163800.0 35000.0 1.08 150320.0 18700.0 0.48 1.1087 0.9343 3558021 ACon1_002355 OCC1OC(C(O)C(O)C1O)c2c(O)cc(O)c3c(=O)cc(oc23)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H12 mock treatment 138600.0 9750.0 0.3 130400.0 -1260.0 -0.03 0.1906 0.6268 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H13 compound treatment 151240.0 22400.0 0.69 143600.0 11900.0 0.31 0.71 0.9341 3616618 ACon1_002356 CC(O)CCCc1cc(O)cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H14 mock treatment 140680.0 11800.0 0.37 118080.0 -13600.0 -0.35 0.0098 0.0192 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H15 compound treatment 138960.0 10100.0 0.31 148440.0 16800.0 0.44 0.5299 0.9869 3616621 ACon1_002357 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@@H]1O)C(=O)O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H16 mock treatment 162920.0 34100.0 1.06 139240.0 7580.0 0.2 0.8858 0.8248 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H17 compound treatment 14600.0 -114000.0 -3.54 16400.0 -115000.0 -2.99 -4.6207 -0.9965 3559631 ACon1_002358 COc1ccc(OC)c(/C=C/C(=O)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H18 mock treatment 126600.0 -2250.0 -0.07 138600.0 6940.0 0.18 0.0783 0.4051 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H19 mock treatment 146160.0 17300.0 0.54 143000.0 11300.0 0.29 0.5877 0.9602 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H20 mock treatment 139920.0 11100.0 0.34 138240.0 6580.0 0.17 0.3635 0.9482 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H21 compound treatment 151200.0 22400.0 0.69 161280.0 29600.0 0.77 1.034 0.9986 3559126 ACon1_002359 CO[C@]1(OC[C@@H]2[C@H](OC[C@@]21O)c3ccc4OCOc4c3)c5ccc6OCOc6c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H22 mock treatment 142280.0 13400.0 0.42 150720.0 19100.0 0.5 0.6445 0.9963 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H23 compound treatment 125720.0 -3130.0 -0.1 121240.0 -10400.0 -0.27 -0.2599 -0.904 3558476 ACon1_002360 COc1cc(C[C@@H]2CO[C@H]([C@@H]2CO)c3ccc(O)c(OC)c3)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 H24 mock treatment 98400.0 -30400.0 -0.94 102840.0 -28800.0 -0.75 -1.1965 -0.9935 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I01 compound treatment 111520.0 -17300.0 -0.54 119640.0 -12000.0 -0.31 -0.6004 -0.9668 1086162 ACon1_002361 COc1c2ccoc2c(OC)c3oc(=O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I02 compound treatment 127640.0 -1210.0 -0.04 120880.0 -10800.0 -0.28 -0.2245 -0.7944 3557472 ACon1_002362 COC1=CC(=O)CC(C)C21Oc3cc(OC)cc(O)c3C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I03 compound treatment 137960.0 9110.0 0.28 125720.0 -5940.0 -0.15 0.0905 0.2814 3553181 ACon1_002363 CC(=C1CC[C@@]2(CO[C@@H]3C2)C1CC[C@]3(O)C(=O)O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I04 compound treatment 15920.0 -113000.0 -3.5 21360.0 -110000.0 -2.87 -4.5006 -0.9951 3616624 ACon1_002364 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(NC(=O)C(C)NC(=O)/C=C/C(=O)O)C(C)c3c[nH]c4ccccc34 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I05 mock treatment 137480.0 8630.0 0.27 116360.0 -15300.0 -0.4 -0.0919 -0.1919 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I06 mock treatment 129880.0 1030.0 0.03 115200.0 -16500.0 -0.43 -0.2798 -0.6523 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I07 compound treatment 126520.0 -2330.0 -0.07 139360.0 7700.0 0.2 0.0905 0.4256 3616627 ACon1_002365 C[C@H]1[C@H](O)CCC2=C[C@@H](O)[C@@]3(O[C@@H]3[C@]12C)C(=C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I08 compound treatment 130960.0 2110.0 0.07 134880.0 3220.0 0.08 0.1055 0.9927 3557433 ACon1_002366 C[C@]1([C@H](O)CC(=O)c2coc3C(=O)c4c5CCC(=O)c5ccc41)c23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I09 compound treatment 121600.0 -7250.0 -0.22 121000.0 -10700.0 -0.28 -0.3546 -0.9946 3554518 ACon1_002367 CO[C@H]1C(=O)Nc2ccc(CC=C(C)C)c(O)c2[C@]1(O)c3ccc(OC)cc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I10 compound treatment 135720.0 6870.0 0.21 135720.0 4060.0 0.11 0.2252 0.9475 3616630 ACon1_002368 COc1cc2oc(C)cc(=O)c2c(O)c1CSCC(O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I11 compound treatment 120920.0 -7930.0 -0.25 120200.0 -11500.0 -0.3 -0.3842 -0.9954 3558142 ACon1_002369 OC[C@H]1O[C@@H](O[C@H]2C[C@@H]3[C@@H]([C@H]4OC(=O)C(=C)[C@@H]4[C@H](O)CC3=C)C2=C)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I12 compound treatment 32800.0 -96000.0 -2.98 31280.0 -100000.0 -2.61 -3.9485 -0.9978 3616631 ACon1_002370 C/C=C/CCCCC(=O)C(C)C(=O)N1CCC=C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I13 compound treatment 125080.0 -3770.0 -0.12 116560.0 -15100.0 -0.39 -0.3599 -0.8793 3554843 ACon1_002371 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)NC(C)C(=O)O)c(O)c3)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4OC(=O)C)c2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I14 compound treatment 131560.0 2710.0 0.08 113000.0 -18700.0 -0.48 -0.2834 -0.5759 1403 ACon1_002372 COC(=O)C1=CCCN(C)C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I15 compound treatment 149880.0 21000.0 0.65 147800.0 16100.0 0.42 0.7574 0.9773 3552057 ACon1_002373 C/C=C/C(O)C(C)CC(C)C(OC(=O)CCC(=O)O)C(C)/C=C/C=C/C=C(\C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I16 compound treatment 63040.0 -65800.0 -2.04 101440.0 -30200.0 -0.79 -1.997 -0.914 3554656 ACon1_002374 COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(=C32)C)c4ccoc4)[C@H](OC(=O)C)C5[C@@](C)(C=CC(=O)[C@]15C)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I17 compound treatment 137160.0 8310.0 0.26 132160.0 500.0 0.01 0.1913 0.7418 3551981 ACon1_002375 C/C(=C\CCC1(C)C2CCC(C2)C1(C)O)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I18 compound treatment 14680.0 -114000.0 -3.54 37120.0 -94500.0 -2.46 -4.2382 -0.9841 3616633 ACon1_002376 COc1cc(cc2OCOc21)C3OCC4C(OCC34)c5ccc(OC)c(OC)c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I19 compound treatment 141840.0 13000.0 0.4 135440.0 3780.0 0.1 0.3541 0.8545 3559399 ACon1_002377 OC[C@H]1O[C@@H](O[C@H](C#N)c2ccccc2)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I20 compound treatment 168080.0 39200.0 1.22 142720.0 11100.0 0.29 1.0628 0.8508 3616634 ACon1_002378 CC(CC(C)OC(=O)/C=C/c1ccc(O)cc1)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I21 mock treatment 140040.0 11200.0 0.35 141480.0 9820.0 0.26 0.4257 0.9886 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I22 mock treatment 160760.0 31900.0 0.99 140040.0 8380.0 0.22 0.8532 0.8426 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I23 compound treatment 138800.0 9950.0 0.31 148440.0 16800.0 0.44 0.5264 0.9856 3559277 ACon1_002379 CC(=O)C12CC(CCC2(C)CCC1O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 I24 compound treatment 120760.0 -8090.0 -0.25 122320.0 -9340.0 -0.24 -0.3488 -0.9999 3616636 ACon1_002380 OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](OC(=O)/C=C/C3(O)C=CC(=O)C=C3)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J01 compound treatment 78760.0 -50100.0 -1.55 95600.0 -36100.0 -0.94 -1.7599 -0.9708 3616638 ACon1_002381 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCC3(C)Oc4cc5occ(c6ccc(O)cc6)c(=O)c5c(O)c4C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J02 mock treatment 114680.0 -14200.0 -0.44 157040.0 25400.0 0.66 0.1559 0.1968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J03 compound treatment 120160.0 -8690.0 -0.27 132240.0 580.0 0.02 -0.1796 -0.6665 3616640 ACon1_002382 CC(=CCc1c(O)c(CC=C(C)C)c2OC(CC(=O)c2c1O)c3ccccc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J04 mock treatment 157800.0 29000.0 0.9 130120.0 -1540.0 -0.04 0.6061 0.6749 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J05 mock treatment 137440.0 8590.0 0.27 121120.0 -10500.0 -0.27 -0.0054 -0.014 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J06 mock treatment 136920.0 8070.0 0.25 115000.0 -16700.0 -0.43 -0.1292 -0.2584 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J07 compound treatment 12400.0 -116000.0 -3.61 12720.0 -119000.0 -3.09 -4.7365 -0.997 3616641 ACon1_002383 CC1(CO)C(CCC2(C)C1CCC3(C)C2CC=C4C5CC(=C)CCC5(CCC43C)C(=O)OC6OC(CO)C(O)C(O)C6OC7OCC(O)C(O)C7O)OC8OC(CO)C(O)C(O)C8O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J08 mock treatment 143080.0 14200.0 0.44 112880.0 -18800.0 -0.49 -0.0332 -0.0504 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J09 compound treatment 124760.0 -4090.0 -0.13 131960.0 300.0 0.01 -0.084 -0.6623 3616643 ACon1_002384 COc1cc(cc2CC(Oc21)C(=C)C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J10 mock treatment 120960.0 -7890.0 -0.24 116240.0 -15400.0 -0.4 -0.4561 -0.9719 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J11 compound treatment 132080.0 3230.0 0.1 132640.0 980.0 0.03 0.0889 0.8595 3616644 ACon1_002385 CC(=CCc1cc2[C@@H]3COc4c(O)c(O)ccc4[C@@H]3Oc2cc1O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J12 mock treatment 133160.0 4310.0 0.13 118320.0 -13300.0 -0.35 -0.1506 -0.4053 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J13 compound treatment 124640.0 -4210.0 -0.13 122440.0 -9220.0 -0.24 -0.2615 -0.959 3616646 ACon1_002386 O[C@@H]1[C@@H](O)[C@H](Oc2ccc(cc2)c3coc4cc(O)ccc4c3=O)O[C@@H]([C@H]1O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J14 mock treatment 114680.0 -14200.0 -0.44 111000.0 -20700.0 -0.54 -0.6899 -0.995 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J15 compound treatment 101880.0 -27000.0 -0.84 100840.0 -30800.0 -0.8 -1.1571 -0.9998 3616648 ACon1_002387 C[C@@H]1O[C@@H](O[C@H]2[C@H](O)CO[C@@H](O[C@H]3[C@H](C)O[C@@H](O[C@@H]4[C@@H](O)[C@H](CO)O[C@H]4OC(=O)[C@@]56CCC(C)(C)C[C@H]6C7=CCC8[C@@]9(C)C[C@H](O)[C@H](O[C@@H]%10O[C@@H]([C@@H](O)[C@H](O)[C@H]%10O)C(=O)O)[C@@](C)(CO)C9[C@H](O)C[C@@]8(C)[C@]7(C)C[C@H]5O)[C@H](O)[C@@H]3O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J16 mock treatment 132760.0 3910.0 0.12 125720.0 -5940.0 -0.15 -0.0234 -0.1191 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J17 compound treatment 122680.0 -6170.0 -0.19 138040.0 6380.0 0.17 -0.0179 -0.0707 3557669 ACon1_002388 C[C@H]1[C@H]2[C@H](CC3[C@@H]4CC=C5C[C@H](O)C[C@@H](O)[C@]5(C)C4CC[C@]23C)O[C@]61OCC(=C)[C@H](O)[C@@H]6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J18 mock treatment 131280.0 2430.0 0.08 117880.0 -13800.0 -0.36 -0.1998 -0.5462 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J19 compound treatment 137800.0 8950.0 0.28 144320.0 12700.0 0.33 0.4288 0.9964 3559791 ACon1_002389 COc1ccc(cc1)C(=O)O[C@H]2CC(=CC[C@@]3(C)[C@@H](O)C[C@@](O)(C(C)C)[C@H]23)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J20 mock treatment 124760.0 -4090.0 -0.13 121360.0 -10300.0 -0.27 -0.2788 -0.9416 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J21 mock treatment 128400.0 -446.0 -0.01 155040.0 23400.0 0.61 0.4198 0.6908 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J22 mock treatment 124200.0 -4650.0 -0.14 134160.0 2500.0 0.06 -0.0559 -0.3537 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J23 mock treatment 132160.0 3310.0 0.1 136600.0 4940.0 0.13 0.1634 0.9939 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 J24 mock treatment 127000.0 -1850.0 -0.06 108480.0 -23200.0 -0.6 -0.4663 -0.7708 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K01 compound treatment 101920.0 -26900.0 -0.83 147200.0 15500.0 0.4 -0.3044 -0.3284 3554199 ACon1_002390 CCc1c(O)cc(O)c2C(=O)C[C@@H](C)Oc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K02 compound treatment 117880.0 -11000.0 -0.34 126720.0 -4940.0 -0.13 -0.331 -0.9114 3559924 ACon1_002391 CC1CCC(=C)/C(=C\C=C/CC1(C)CCC2=CC(=O)OC2O)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K03 compound treatment 125720.0 -3130.0 -0.1 144280.0 12600.0 0.33 0.1634 0.4778 3558269 ACon1_002392 C[C@@]1(O)CCC[C@]2(C)CC[C@H](C[C@@H]12)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K04 compound treatment 11720.0 -117000.0 -3.63 13800.0 -118000.0 -3.06 -4.7315 -0.9964 3559641 ACon1_002393 O/C(=C\C(=O)/C=C/c1ccccc1)/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K05 compound treatment 117800.0 -11000.0 -0.34 114920.0 -16700.0 -0.43 -0.5496 -0.993 3554959 ACon1_002394 COc1cc(O)c(C(=O)C)c(CC(=O)O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K06 compound treatment 125000.0 -3850.0 -0.12 129840.0 -1820.0 -0.05 -0.1177 -0.9181 3616650 ACon1_002395 COc1cc(oc(=O)c1C)/C(=C/C(C)O)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K07 mock treatment 139120.0 10300.0 0.32 104480.0 -27200.0 -0.71 -0.2743 -0.3541 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K08 mock treatment 124880.0 -3970.0 -0.12 123400.0 -8260.0 -0.21 -0.2386 -0.965 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K09 compound treatment 105080.0 -23800.0 -0.74 111040.0 -20600.0 -0.54 -0.8995 -0.9878 3559867 ACon1_002396 COc1c(O)cc2CCNC3Cc4ccccc4-c1c32 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K10 compound treatment 10000.0 -119000.0 -3.68 10040.0 -122000.0 -3.16 -4.8383 -0.9971 3616653 ACon1_002397 CC(CCO)/C=C(/C)\C=C\C1=CC2=CC(=O)C(C)(O)C(O)C2=CO1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K11 compound treatment 9760.0 -119000.0 -3.69 10480.0 -121000.0 -3.15 -4.8355 -0.9969 3558744 ACon1_002398 COc1cc(/C=C/CO)cc(OC)c1OC\C=C(/C)\CCC=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K12 compound treatment 125040.0 -3810.0 -0.12 141360.0 9700.0 0.25 0.0948 0.3408 3616654 ACon1_002399 CC1CCCC[C@@H]2[C@@H](CC(=O)O1)[C@@H](O)C=CC2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K13 compound treatment 129840.0 994.0 0.03 130480.0 -1180.0 -0.03 1.0E-4 0.0023 3557992 ACon1_002400 C[C@@H]1C[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@]2(COC(=O)C)[C@@H](C[C@@H]3[C@@H](OC(=O)C)[C@]12OC3(C)C)OC(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K14 compound treatment 11720.0 -117000.0 -3.63 12320.0 -119000.0 -3.1 -4.7587 -0.9969 2732 ACon1_002401 Cc1cc(=O)oc2cc(O)ccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K15 mock treatment 116720.0 -12100.0 -0.38 120960.0 -10700.0 -0.28 -0.4623 -0.989 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K16 mock treatment 121400.0 -7450.0 -0.23 111960.0 -19700.0 -0.51 -0.5251 -0.9352 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K17 compound treatment 124400.0 -4450.0 -0.14 146120.0 14500.0 0.38 0.1683 0.4205 3554976 ACon1_002402 COc1cc(O)c(Oc2cc(C)cc(O)c2C(=O)O)c(CO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K18 compound treatment 131720.0 2870.0 0.09 145200.0 13500.0 0.35 0.3117 0.859 3616656 ACon1_002403 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1[C@@H](C[C@]3(C)OC(=O)C)OC(=O)/C=C/c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K19 compound treatment 116920.0 -11900.0 -0.37 152960.0 21300.0 0.55 0.13 0.1954 3559928 ACon1_002404 COC1OC(=O)C(=C1)CCC2(C)C/C=C\C=C(\C(=O)O)/C(=C)CCC2C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K20 compound treatment 36040.0 -92800.0 -2.88 55840.0 -75800.0 -1.97 -3.4263 -0.983 3558737 ACon1_002405 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K21 compound treatment 107440.0 -21400.0 -0.66 137200.0 5540.0 0.14 -0.3672 -0.541 3557421 ACon1_002406 Cc1cc(O)cc(Oc2cc(C)cc(O)c2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K22 compound treatment 9840.0 -119000.0 -3.69 11280.0 -120000.0 -3.13 -4.819 -0.9966 3616657 ACon1_002407 CC1CCC2(CCC3(C(=O)O)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C)C(=O)OC6OC(CO)C(O)C(O)C6O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K23 mock treatment 123040.0 -5810.0 -0.18 132800.0 1140.0 0.03 -0.1063 -0.5828 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 K24 mock treatment 106000.0 -22800.0 -0.71 132560.0 900.0 0.02 -0.484 -0.6834 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L01 compound treatment 95560.0 -33300.0 -1.03 129360.0 -2300.0 -0.06 -0.7715 -0.7468 3616659 ACon1_002408 C/C(=C\CCC(=C)C1(O)CCC(=CC1)C)/C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L02 mock treatment 137680.0 8830.0 0.27 124800.0 -6860.0 -0.18 0.0675 0.2067 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L03 compound treatment 64800.0 -64000.0 -1.98 64600.0 -67100.0 -1.74 -2.6353 -0.9979 3616661 ACon1_002409 OC(=O)C(Cc1ccc(O)c(O)c1)OC(=O)/C=C/c2ccc3O[C@@H]([C@@H](Oc3c2)C(=O)O)c4ccc(O)c(O)c4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L04 mock treatment 122720.0 -6130.0 -0.19 119280.0 -12400.0 -0.32 -0.3617 -0.9683 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L05 compound treatment 139840.0 11000.0 0.34 126920.0 -4740.0 -0.12 0.1538 0.4246 3616663 ACon1_002410 COC(=O)C1CC(=O)C[C@@H]2[C@@]1(C)CC[C@@H]3C(=O)O[C@@H](C[C@]32C)c4ccoc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L06 mock treatment 128120.0 -726.0 -0.02 121560.0 -10100.0 -0.26 -0.2015 -0.7649 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L07 mock treatment 119440.0 -9410.0 -0.29 119600.0 -12100.0 -0.31 -0.4277 -0.9993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L08 mock treatment 132760.0 3910.0 0.12 121960.0 -9700.0 -0.25 -0.0925 -0.3306 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L09 compound treatment 124080.0 -4770.0 -0.15 126560.0 -5100.0 -0.13 -0.1981 -0.9985 3616665 ACon1_002411 C/C(=C\CCC(C)(OC1OCC(O)C(O)C1OC(=O)\C(=C\CCC(C)(O)C=C)\C)C=C)/C(=O)OC2CC3(C(O)CC4(C)C(=CCC5C6(C)CCC(OC7OC(CO)C(OC8OC(CO)C(O)C(OC9OCC(O)C(O)C9O)C8O)C(O)C7O)C(C)(C)C6CCC54C)C3CC2(C)C)C(=O)OC%10OCC(OC%11OC(CO)C(O)C(OC%12OC(CO)C(OC%13OC(CO)C(O)C(O)C%13O)C(O)C%12O)C%11O)C(O)C%10O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L10 mock treatment 127840.0 -1010.0 -0.03 109600.0 -22100.0 -0.57 -0.4273 -0.7445 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L11 compound treatment 9200.0 -120000.0 -3.71 9720.0 -122000.0 -3.17 -4.8617 -0.9969 3616667 ACon1_002412 CC1OC(OC2C(O)C(O)C(C)OC2OC3(C)CC(OC4OC(CO)C(O)C(OC(=O)C)C4O)C5C(CCC6C(C)(C)CCCC65C)O3)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L12 mock treatment 121200.0 -7650.0 -0.24 101200.0 -30500.0 -0.79 -0.7271 -0.8802 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L13 compound treatment 98520.0 -30300.0 -0.94 118400.0 -13300.0 -0.34 -0.908 -0.9073 3558283 ACon1_002413 C[C@H]1[C@H]2[C@H](CC3C4C[C@@H](O)[C@H]5C[C@@H](O[C@@H]6O[C@H](CO)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]9O[C@H](CO)[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]6O)[C@H](O)C[C@]5(C)C4CC[C@]23C)O[C@@]%111CCC(C)CO%11 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L14 mock treatment 129880.0 1030.0 0.03 98360.0 -33300.0 -0.87 -0.5892 -0.6805 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L15 mock treatment 115000.0 -13800.0 -0.43 114160.0 -17500.0 -0.45 -0.6249 -0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L16 mock treatment 126600.0 -2250.0 -0.07 114760.0 -16900.0 -0.44 -0.3597 -0.8091 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L17 compound treatment 125080.0 -3770.0 -0.12 122960.0 -8700.0 -0.23 -0.2424 -0.9527 3559686 ACon1_002414 COc1ccc(C[C@H]2COC(=O)[C@]2(O)Cc3ccc(O)c(OC)c3)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L18 mock treatment 131280.0 2430.0 0.08 120120.0 -11500.0 -0.3 -0.1587 -0.5133 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L19 compound treatment 133640.0 4790.0 0.15 125080.0 -6580.0 -0.17 -0.0159 -0.07 3557479 ACon1_002415 CC(=CCc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccc(O)c(O)c3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L20 mock treatment 128160.0 -686.0 -0.02 114360.0 -17300.0 -0.45 -0.3329 -0.7397 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L21 compound treatment 105720.0 -23100.0 -0.72 136680.0 5020.0 0.13 -0.4144 -0.569 3558013 ACon1_002416 CC(=O)O[C@H]1CC(C)(C)CC2[C@@]31CO[C@]42CCC5[C@@]6(C)CC[C@H](O[C@@H]7OC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@H]9OC[C@@H](O[C@@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]7O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)[C@@](C)(CO)C6CC[C@@]5(C)[C@]4(C)C[C@H]3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L22 mock treatment 134200.0 5350.0 0.17 130160.0 -1500.0 -0.04 0.0897 0.5266 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L23 mock treatment 127920.0 -926.0 -0.03 127520.0 -4140.0 -0.11 -0.0963 -0.8654 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 L24 mock treatment 104640.0 -24200.0 -0.75 116000.0 -15700.0 -0.41 -0.8181 -0.9587 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M01 compound treatment 120600.0 -8250.0 -0.26 168200.0 36500.0 0.95 0.4907 0.4991 3557425 ACon1_002417 C/C=C(\C)/C(=O)OC1CCC(=O)OC1\C=C\C(O)C(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M02 compound treatment 96200.0 -32600.0 -1.01 123000.0 -8660.0 -0.23 -0.8744 -0.8438 3557333 ACon1_002418 Cc1cc2cc(O)cc(O)c2c(=O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M03 compound treatment 114080.0 -14800.0 -0.46 144960.0 13300.0 0.35 -0.0792 -0.1381 3559679 ACon1_002419 COC(=O)[C@@H]1C[C@@H](O)C[C@]2(C)[C@@H]1CC[C@]3(C[C@H]4CC[C@H]32)[C@@H](O)C4=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M04 compound treatment 8360.0 -120000.0 -3.73 10640.0 -121000.0 -3.14 -4.8632 -0.9964 1110474 ACon1_002420 COc1ccc2c(=O)c(O)c(oc2c1)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M05 compound treatment 119720.0 -9130.0 -0.28 141280.0 9620.0 0.25 -0.0232 -0.0615 3553164 ACon1_002421 C1Oc2ccc(cc2O1)[C@H]3OC[C@@H]4[C@H](OC[C@H]34)c5ccc6OCOc6c5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M06 compound treatment 110160.0 -18700.0 -0.58 132280.0 620.0 0.02 -0.398 -0.6872 3557719 ACon1_002422 CCCCC/C=C/C=C/C(O)CCCCCCCC(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M07 compound treatment 16520.0 -112000.0 -3.48 18920.0 -113000.0 -2.93 -4.5323 -0.9963 3616668 ACon1_002423 CO[C@H]1C[C@H](C)[C@@H](OC)C2=CC(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M08 compound treatment 59520.0 -69300.0 -2.15 51880.0 -79800.0 -2.07 -2.9847 -0.9998 3559706 ACon1_002424 COc1cc(O)c2c(=O)cc(oc2c1)c3cc(OC)c(OC)c(O)c3OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M09 mock treatment 126960.0 -1890.0 -0.06 144240.0 12600.0 0.33 0.1898 0.5716 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M10 mock treatment 129120.0 274.0 0.01 125160.0 -6500.0 -0.17 -0.1134 -0.6707 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M11 compound treatment 8800.0 -120000.0 -3.72 10520.0 -121000.0 -3.15 -4.8558 -0.9965 3558746 ACon1_002425 COc1cc(/C=C/CO)ccc1OC\C=C(/C)\CCC=C(C)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M12 compound treatment 21880.0 -107000.0 -3.31 24760.0 -107000.0 -2.78 -4.3076 -0.9961 3616671 ACon1_002426 COc1c(O)cc2C(Oc3cc(C)oc(=O)c3)C(C)OC(=O)c2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M13 mock treatment 104360.0 -24500.0 -0.76 130720.0 -940.0 -0.02 -0.5537 -0.7295 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M14 mock treatment 156720.0 27900.0 0.86 137880.0 6220.0 0.16 0.725 0.8251 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M15 compound treatment 118600.0 -10200.0 -0.32 136640.0 4980.0 0.13 -0.133 -0.3879 3554561 ACon1_002427 COC(=O)[C@]1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(=C1c3ccc(O)cc3)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M16 compound treatment 127640.0 -1210.0 -0.04 145520.0 13900.0 0.36 0.2282 0.6304 3616673 ACon1_002428 COC(=O)[C@]1(O)[C@H](O)C(=O)C(=C1/C=C/C)Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M17 compound treatment 126760.0 -2090.0 -0.06 118880.0 -12800.0 -0.33 -0.2805 -0.8292 3554697 ACon1_002429 COC(=O)c1c(O)cc(C)cc1Oc2c(O)cc(OC)cc2CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M18 compound treatment 124760.0 -4090.0 -0.13 108640.0 -23000.0 -0.6 -0.5125 -0.8382 3616676 ACon1_002430 COc1cc(O)cc(C)c1C(=O)OC2C(CO)OC(C2OC(=O)C)n3ccc(=O)[nH]c3=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M19 compound treatment 121640.0 -7210.0 -0.22 139560.0 7900.0 0.21 -0.0127 -0.042 3616679 ACon1_002431 COC(CC(c1c(O)cc2cc(C)oc(=O)c2c1O)c3c(O)cc4cc(C)oc(=O)c4c3O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M20 compound treatment 121080.0 -7770.0 -0.24 135960.0 4300.0 0.11 -0.0911 -0.3436 3616682 ACon1_002432 OC[C@H]1O[C@@H](Oc2c(O)cccc2COC(=O)C3(O)C4C5C6C7C5C(C7C(O)(C(=O)OCc8cccc(O)c8O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C(=O)C64)C3=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M21 compound treatment 141800.0 13000.0 0.4 134320.0 2660.0 0.07 0.3327 0.8168 3552105 ACon1_002433 C/C=C/C1OC2=C(C(O)C1O)C(=O)OC2=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M22 compound treatment 87280.0 -41600.0 -1.29 117880.0 -13800.0 -0.36 -1.1639 -0.8707 3616684 ACon1_002434 CC1CCC2(CCC3(C(=O)O)C(=CCC4C5(C)CCC(OC6OC(C)C(O)C(=O)C6O)C(C)(C)C5CCC43C)C2C1C)C(=O)OC7OC(CO)C(O)C(O)C7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M23 compound treatment 133320.0 4470.0 0.14 153640.0 22000.0 0.57 0.5019 0.8539 3559395 ACon1_002435 C/C=C\1/[C@H](CC(=O)OCCc2ccc(O)cc2)C(=CO[C@H]1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 M24 compound treatment 118560.0 -10300.0 -0.32 130920.0 -740.0 -0.02 -0.239 -0.7484 3559231 ACon1_002436 C[C@@H]1O[C@@H](O[C@@H]2[C@@H]3O[C@]3(CO)[C@@H]4[C@H]2C=CO[C@H]4O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](OC(=O)/C=C/c6ccccc6)[C@H](OC(=O)C)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N01 compound treatment 122000.0 -6850.0 -0.21 159480.0 27800.0 0.72 0.3611 0.4794 2090630 ACon1_002437 CC1OC(OCC2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)cc5)C(OC6OC(C)C(O)C(O)C6O)C(O)C2O)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N02 mock treatment 106080.0 -22800.0 -0.71 151880.0 20200.0 0.53 -0.1273 -0.1447 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N03 compound treatment 98120.0 -30700.0 -0.95 132520.0 860.0 0.02 -0.6574 -0.6903 3616685 ACon1_002438 CC(=CCc1cc2C(=O)[C@H](O)[C@H](Oc2c(CC=C(C)C)c1O)c3ccc(O)cc3)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N04 mock treatment 135560.0 6710.0 0.21 135960.0 4300.0 0.11 0.2261 0.9575 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N05 compound treatment 30520.0 -98300.0 -3.05 46080.0 -85600.0 -2.22 -3.7266 -0.988 3616688 ACon1_002439 C[C@]12C[C@H](OC(=O)[C@H]2CC[C@]3(C)[C@H]1CCC=C3C(=O)O)c4ccoc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N06 mock treatment 129760.0 914.0 0.03 134320.0 2660.0 0.07 0.0689 0.9224 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N07 compound treatment 43640.0 -85200.0 -2.64 54880.0 -76800.0 -1.99 -3.2775 -0.9905 3616690 ACon1_002440 COc1cc2C[C@H]3COC(=O)[C@@H]3Cc4cc5OCOc5cc4-c2c(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N08 mock treatment 121720.0 -7130.0 -0.22 112200.0 -19500.0 -0.51 -0.5137 -0.931 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N09 mock treatment 124560.0 -4290.0 -0.13 114520.0 -17100.0 -0.45 -0.4088 -0.8797 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N10 mock treatment 129040.0 194.0 0.01 118960.0 -12700.0 -0.33 -0.2291 -0.6941 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N11 compound treatment 134720.0 5870.0 0.18 139720.0 8060.0 0.21 0.2768 0.9976 3616692 ACon1_002441 CO[C@@H]1[C@@H](O)[C@@H](O[C@H]2CC[C@]3(C)C4C[C@@H]5C(=C)[C@H](CC[C@]5(O)[C@@H]4CC[C@@H]3C2)C6=CC(=O)OC6)O[C@@H](C)[C@H]1O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N12 mock treatment 113880.0 -15000.0 -0.46 131720.0 60.0 0.0 -0.3268 -0.7047 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N13 mock treatment 122720.0 -6130.0 -0.19 124000.0 -7660.0 -0.2 -0.2749 -0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N14 mock treatment 135320.0 6470.0 0.2 143800.0 12100.0 0.32 0.3649 0.9761 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N15 compound treatment 56680.0 -72200.0 -2.24 53160.0 -78500.0 -2.04 -3.0234 -0.9989 3616695 ACon1_002442 COc1cc2nc3occc3c(OC)c2cc1OCC(O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N16 mock treatment 114240.0 -14600.0 -0.45 120480.0 -11200.0 -0.29 -0.5254 -0.977 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N17 compound treatment 120600.0 -8250.0 -0.26 118520.0 -13100.0 -0.34 -0.4221 -0.9898 3559633 ACon1_002443 C/C(=C/CCC(C)(O)C=C)/CCC(=O)C(C)(C)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N18 mock treatment 112520.0 -16300.0 -0.51 106840.0 -24800.0 -0.64 -0.8137 -0.9928 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N19 compound treatment 122560.0 -6290.0 -0.19 145120.0 13500.0 0.35 0.1096 0.2737 3558393 ACon1_002444 CC(C)C1CCC(=CCCC2(C)OC2C1OC3OC(COC(=O)C)C(O)C(O)C3O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N20 mock treatment 130040.0 1190.0 0.04 132040.0 380.0 0.01 0.0331 0.8655 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N21 compound treatment 109200.0 -19600.0 -0.61 150200.0 18500.0 0.48 -0.0898 -0.1157 3558493 ACon1_002445 COc1cc(CC2COC(C2COC(=O)/C=C/c3ccc(O)cc3)c4ccc(O)c(OC)c4)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N22 mock treatment 144520.0 15700.0 0.49 138640.0 6980.0 0.18 0.4716 0.9098 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N23 mock treatment 117480.0 -11400.0 -0.35 130880.0 -780.0 -0.02 -0.2634 -0.7466 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 N24 mock treatment 108480.0 -20400.0 -0.63 127280.0 -4380.0 -0.11 -0.5267 -0.8214 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O01 compound treatment 92080.0 -36800.0 -1.14 108800.0 -22900.0 -0.59 -1.2255 -0.9539 3557529 ACon1_002446 COc1cc(OC)c2C(=O)CC(Oc2c1O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O02 compound treatment 29280.0 -99600.0 -3.08 39760.0 -91900.0 -2.39 -3.8699 -0.992 3559907 ACon1_002447 CC1(C2CC3CC21)C3(C)CCC(O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O03 compound treatment 27320.0 -102000.0 -3.15 13760.0 -118000.0 -3.06 -4.3905 -0.9999 3559525 ACon1_002448 O[C@]12CCC(=C)[C@@H]3CCC(=C)[C@@H]3[C@H]2OC(=O)C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O04 compound treatment 85440.0 -43400.0 -1.34 126320.0 -5340.0 -0.14 -1.0491 -0.7759 3559658 ACon1_002449 COc1ccc(CCC(=O)c2ccc(OC)cc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O05 compound treatment 115720.0 -13100.0 -0.41 144880.0 13200.0 0.34 -0.0447 -0.084 360 ACon1_002450 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O06 compound treatment 127480.0 -1370.0 -0.04 140920.0 9260.0 0.24 0.1402 0.5739 3555974 ACon1_002451 OCCCCCCC(C(=O)O)C(=C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O07 compound treatment 91720.0 -37100.0 -1.15 124520.0 -7140.0 -0.19 -0.9446 -0.8107 3559619 ACon1_002452 OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(CO)[C@H]32)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O08 compound treatment 77840.0 -51000.0 -1.58 115800.0 -15900.0 -0.41 -1.4089 -0.8626 3557500 ACon1_002453 C[C@H]1[C@H]2[C@H](OC1=O)/C=C(\C)/CC/C=C(\CO)/C[C@H]2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O09 compound treatment 110760.0 -18100.0 -0.56 125960.0 -5700.0 -0.15 -0.501 -0.8643 3553872 ACon1_002454 CC1(C)O[C@H]2CC(=O)OC[C@@]23[C@H]1CC(=O)[C@]4(C)[C@@H]3CC[C@@]5(C)[C@@H](OC(=O)C=C54)c6ccoc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O10 compound treatment 109960.0 -18900.0 -0.59 119120.0 -12500.0 -0.33 -0.6442 -0.9618 3616698 ACon1_002455 CC1CCC(O)C2C=CC(C)(O)C(C)(C12)C(=O)CCO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O11 mock treatment 117120.0 -11700.0 -0.36 125760.0 -5900.0 -0.15 -0.3653 -0.9264 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O12 mock treatment 118120.0 -10700.0 -0.33 116920.0 -14700.0 -0.38 -0.5058 -0.9975 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O13 compound treatment 17800.0 -111000.0 -3.44 18160.0 -114000.0 -2.95 -4.5182 -0.9971 3554856 ACon1_002456 COc1cc(C=C)cc2c(=O)oc3c(cc(OC)c4c(O)ccc([C@@H]5O[C@H](C)[C@H](O)[C@@H]([C@H]5O)N(C)C)c34)c12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O14 compound treatment 120640.0 -8210.0 -0.25 147480.0 15800.0 0.41 0.1109 0.2294 3559702 ACon1_002457 O[C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O15 compound treatment 110440.0 -18400.0 -0.57 116200.0 -15500.0 -0.4 -0.6873 -0.9853 3553713 ACon1_002458 CC(CCCCC(O)C(CO)C(=O)O)C/C(=C/C(=C/C(=O)O)/C)/C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O16 compound treatment 105120.0 -23700.0 -0.74 135440.0 3780.0 0.1 -0.4504 -0.6072 3553071 ACon1_002459 C[C@H]1[C@H](O)CCC2=CC(=O)C(=C(C)C)C[C@]12CO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O17 compound treatment 121320.0 -7530.0 -0.23 129240.0 -2420.0 -0.06 -0.2094 -0.8668 3553691 ACon1_002460 CC(CC(=O)N)OC(=O)c1cc(Cl)cc(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O18 compound treatment 10120.0 -119000.0 -3.68 13960.0 -118000.0 -3.06 -4.7637 -0.9958 3616699 ACon1_002461 CC(=O)O[C@@]1(C)C[C@@H](OC(=O)/C=C/c2ccc(O)cc2)[C@H]3[C@@H]1C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C3C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O19 compound treatment 110960.0 -17900.0 -0.55 167160.0 35500.0 0.92 0.2604 0.242 3559916 ACon1_002462 CC(C)(O)CCc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(O)c3C(=O)[C@H](O)[C@H](Oc13)c4ccc(O)cc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O20 compound treatment 56520.0 -72300.0 -2.24 79280.0 -52400.0 -1.36 -2.547 -0.9714 1017609 ACon1_002463 CC(=CCc1c(O)c2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc(O)cc4)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O21 compound treatment 119000.0 -9850.0 -0.31 129600.0 -2060.0 -0.05 -0.2536 -0.8187 3554292 ACon1_002464 CCCCCCCC(O)C(O)C1CC(=CC(=O)O1)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O22 compound treatment 99280.0 -29600.0 -0.92 126880.0 -4780.0 -0.12 -0.7356 -0.7957 3558536 ACon1_002465 CC1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(C)CCC6(CCC54C(=O)O)C(=O)OC7OC(CO)C(O)C(O)C7O)C2(C)C)C(O)C(O)C1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O23 compound treatment 137680.0 8830.0 0.27 125400.0 -6260.0 -0.16 0.0785 0.2467 3616706 ACon1_002466 CC1CC(=O)c2cc(O)c(O)cc2C1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 O24 compound treatment 114000.0 -14800.0 -0.46 132480.0 820.0 0.02 -0.3102 -0.6736 3615046 ACon1_002467 COC1OC2C(N(C)CCc3cc4OCOc4cc23)c5ccc6OCOc6c15 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P01 compound treatment 86040.0 -42800.0 -1.33 74840.0 -56800.0 -1.48 -1.9818 -0.9986 3616709 ACon1_002468 C[C@@]1(CCC2C(=CCC3[C@@](C)(CCC[C@]23C)C(=O)O)C1)C=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P02 mock treatment 105880.0 -23000.0 -0.71 115360.0 -16300.0 -0.42 -0.8026 -0.9693 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P03 compound treatment 121160.0 -7690.0 -0.24 138440.0 6780.0 0.18 -0.0438 -0.148 3616713 ACon1_002469 COC(=O)[C@@H](O)[C@@H]1[C@@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C[C@]54O[C@@H]6C([C@@]2(O)C[C@@]1(C)[C@@H]6O)[C@@]35O)c7ccoc7 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P04 mock treatment 114800.0 -14000.0 -0.44 128320.0 -3340.0 -0.09 -0.3691 -0.8317 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P05 compound treatment 99600.0 -29200.0 -0.91 116600.0 -15100.0 -0.39 -0.9175 -0.9295 3616715 ACon1_002470 OC[C@H]1O[C@@H](Oc2ccc(cc2)c3coc4c([C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P06 mock treatment 107120.0 -21700.0 -0.67 127120.0 -4540.0 -0.12 -0.5594 -0.8185 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P07 compound treatment 110240.0 -18600.0 -0.58 126440.0 -5220.0 -0.14 -0.5035 -0.8503 3616718 ACon1_002471 C[C@@H]1CC[C@@]2(CC[C@]3(C(=O)O)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P08 mock treatment 113920.0 -14900.0 -0.46 117760.0 -13900.0 -0.36 -0.5824 -0.9925 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P09 compound treatment 101840.0 -27000.0 -0.84 144400.0 12700.0 0.33 -0.3576 -0.3974 3616720 ACon1_002472 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCc3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P10 mock treatment 98080.0 -30800.0 -0.95 110160.0 -21500.0 -0.56 -1.0691 -0.9676 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P11 mock treatment 120480.0 -8370.0 -0.26 131520.0 -140.0 0.0 -0.1859 -0.717 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P12 mock treatment 120360.0 -8490.0 -0.26 106600.0 -25100.0 -0.65 -0.6463 -0.9204 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P13 compound treatment 115320.0 -13500.0 -0.42 117720.0 -13900.0 -0.36 -0.5525 -0.9974 3616724 ACon1_002473 COc1cc2nc3occc3c(OC)c2cc1OCC(OC(=O)C)C(C)(C)OC(=O)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P14 mock treatment 114160.0 -14700.0 -0.46 124200.0 -7460.0 -0.19 -0.4588 -0.9277 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P15 compound treatment 116120.0 -12700.0 -0.39 122320.0 -9340.0 -0.24 -0.4504 -0.9728 3616725 ACon1_002474 CCCCCc1cc(OC)c2CC(O)C(C)(C)Oc2c1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P16 mock treatment 107880.0 -21000.0 -0.65 120920.0 -10700.0 -0.28 -0.6567 -0.9288 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P17 compound treatment 110960.0 -17900.0 -0.55 114880.0 -16800.0 -0.44 -0.7002 -0.993 1001668 ACon1_002475 CC(=CCCC1(C)Oc2c(C)cc3c4ccccc4[nH]c3c2C=C1)C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P18 mock treatment 107600.0 -21200.0 -0.66 101680.0 -30000.0 -0.78 -1.0163 -0.9965 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P19 compound treatment 41200.0 -87600.0 -2.72 47080.0 -84600.0 -2.2 -3.4742 -0.9945 3554138 ACon1_002476 CCC(C)C(=O)O[C@@H]1[C@H]2[C@@H](O)[C@@H](C)C[C@]2(O)C(=O)[C@@H](C)/C=C/C(C)(C)[C@H](O)[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)CC)C1=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P20 mock treatment 101760.0 -27100.0 -0.84 122920.0 -8740.0 -0.23 -0.754 -0.8673 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P21 compound treatment 82200.0 -46600.0 -1.45 96080.0 -35600.0 -0.92 -1.6757 -0.9767 3559753 ACon1_002477 COC1=CC2(CCN(C)[C@@H]3Cc4cc(OC)c(OC)cc42)C3=CC1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P22 mock treatment 111680.0 -17200.0 -0.53 112880.0 -18800.0 -0.49 -0.7211 -0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P23 mock treatment 71840.0 -57000.0 -1.77 78160.0 -53500.0 -1.39 -2.2319 -0.993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2297 P24 mock treatment 85280.0 -43600.0 -1.35 74800.0 -56900.0 -1.48 -1.9992 -0.999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A01 compound treatment 93600.0 -51400.0 -1.59 132440.0 -22800.0 -0.59 -1.5445 -0.9094 3213058 CHDI2_000001 NNC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A02 compound treatment 48280.0 -96700.0 -3.0 54520.0 -101000.0 -2.62 -3.969 -0.9977 3213102 CHDI2_000002 ONC(=O)CCCCCCC(=O)N/N=C/c1c(O)ccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A03 compound treatment 8320.0 -137000.0 -4.23 9880.0 -145000.0 -3.78 -5.6646 -0.9984 3213060 CHDI2_000003 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A04 compound treatment 14320.0 -131000.0 -4.05 14040.0 -141000.0 -3.67 -5.4567 -0.9988 3213106 CHDI2_000004 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A05 compound treatment 36000.0 -109000.0 -3.38 32720.0 -123000.0 -3.18 -4.6385 -0.9996 3213064 CHDI2_000005 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A06 compound treatment 146880.0 1910.0 0.06 46880.0 -108000.0 -2.82 -1.9491 -0.6921 3213110 CHDI2_000006 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc([N+](=O)[O-])c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A07 compound treatment 16040.0 -129000.0 -3.99 15920.0 -139000.0 -3.62 -5.3845 -0.9988 3213068 CHDI2_000007 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A08 compound treatment 171360.0 26400.0 0.82 95680.0 -59600.0 -1.55 -0.5162 -0.2949 3213114 CHDI2_000008 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(O)ccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A09 compound treatment 18880.0 -126000.0 -3.91 14440.0 -141000.0 -3.66 -5.3495 -0.9995 3213072 CHDI2_000009 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2OCCOc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A10 compound treatment 128160.0 -16800.0 -0.52 63080.0 -92200.0 -2.39 -2.0616 -0.8412 3213118 CHDI2_000010 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)n2ccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A11 compound treatment 178000.0 33000.0 1.02 93400.0 -61800.0 -1.61 -0.4126 -0.2166 3213076 CHDI2_000011 ONC(=O)CCCCCCC(=O)N/N=C/COCc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A12 compound treatment 48520.0 -96400.0 -2.99 29640.0 -126000.0 -3.26 -4.4208 -0.999 3213122 CHDI2_000012 ONC(=O)CCCCCCC(=O)N/N=C/c1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A13 compound treatment 10240.0 -135000.0 -4.17 8400.0 -147000.0 -3.82 -5.6498 -0.999 3214258 CHDI2_000013 ONC(=O)CCCCCC(=O)N/N=C/c1c(O)ccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A14 compound treatment 196280.0 51300.0 1.59 143680.0 -11600.0 -0.3 0.9117 0.5635 3214354 CHDI2_000014 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A15 compound treatment 8760.0 -136000.0 -4.22 8440.0 -147000.0 -3.81 -5.6814 -0.9987 3213080 CHDI2_000015 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A16 compound treatment 7440.0 -138000.0 -4.26 8120.0 -147000.0 -3.82 -5.7162 -0.9985 3213126 CHDI2_000016 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(I)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A17 compound treatment 6680.0 -138000.0 -4.28 6480.0 -149000.0 -3.87 -5.763 -0.9987 3213084 CHDI2_000017 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A18 compound treatment 61960.0 -83000.0 -2.57 49680.0 -106000.0 -2.74 -3.7582 -0.9995 3213130 CHDI2_000018 C/C=C(/C)\C=N\NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A19 compound treatment 88040.0 -56900.0 -1.76 65680.0 -89600.0 -2.33 -2.8928 -0.9907 3213088 CHDI2_000019 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A20 compound treatment 6320.0 -139000.0 -4.3 5920.0 -149000.0 -3.88 -5.7812 -0.9987 3213206 CHDI2_000020 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(s1)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A21 compound treatment 8320.0 -137000.0 -4.23 8280.0 -147000.0 -3.82 -5.694 -0.9987 3213092 CHDI2_000021 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Br)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A22 compound treatment 60560.0 -84400.0 -2.62 72000.0 -83200.0 -2.16 -3.3788 -0.9955 3213138 CHDI2_000022 Cc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A23 mock treatment 258080.0 113000.0 3.5 218840.0 63600.0 1.65 3.6466 0.9411 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 A24 mock treatment 113000.0 -32000.0 -0.99 159160.0 3910.0 0.1 -0.6285 -0.6312 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B01 compound treatment 227760.0 82800.0 2.57 220000.0 64800.0 1.68 3.0036 0.9791 3213059 CHDI2_000023 NNC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B02 compound treatment 88720.0 -56200.0 -1.74 75400.0 -79800.0 -2.07 -2.6993 -0.9962 3213100 CHDI2_000024 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B03 compound treatment 209320.0 64400.0 1.99 180040.0 24800.0 0.64 1.8654 0.8903 3213062 CHDI2_000025 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B04 compound treatment 89200.0 -55800.0 -1.73 96760.0 -58500.0 -1.52 -2.2964 -0.9979 3213104 CHDI2_000026 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B05 compound treatment 141560.0 -3410.0 -0.11 179680.0 24400.0 0.63 0.3742 0.5815 3213066 CHDI2_000027 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B06 compound treatment 159000.0 14000.0 0.43 160160.0 4910.0 0.13 0.3977 0.8777 3213108 CHDI2_000028 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B07 compound treatment 184480.0 39500.0 1.22 145440.0 -9810.0 -0.25 0.6855 0.5482 3213070 CHDI2_000029 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B08 compound treatment 168680.0 23700.0 0.73 137360.0 -17900.0 -0.46 0.1909 0.2196 3213112 CHDI2_000030 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B09 compound treatment 202120.0 57200.0 1.77 159080.0 3830.0 0.1 1.3226 0.7457 3213074 CHDI2_000031 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3OCCOc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B10 compound treatment 133760.0 -11200.0 -0.35 219240.0 64000.0 1.66 0.9302 0.5476 3213116 CHDI2_000032 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B11 compound treatment 141040.0 -3930.0 -0.12 187880.0 32600.0 0.85 0.5135 0.5995 3213078 CHDI2_000033 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/COCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B12 compound treatment 138440.0 -6530.0 -0.2 156240.0 994.0 0.03 -0.1248 -0.6119 3213120 CHDI2_000034 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2c[nH]c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B13 compound treatment 229120.0 84200.0 2.61 219440.0 64200.0 1.67 3.0231 0.9767 3214500 CHDI2_000035 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B14 mock treatment 140440.0 -4530.0 -0.14 237000.0 81800.0 2.12 1.4028 0.659 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B15 compound treatment 149240.0 4270.0 0.13 198680.0 43400.0 1.13 0.8916 0.7847 3213082 CHDI2_000036 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B16 compound treatment 157920.0 13000.0 0.4 213840.0 58600.0 1.52 1.3603 0.864 3213124 CHDI2_000037 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(I)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B17 compound treatment 145280.0 312.0 0.01 95080.0 -60200.0 -1.56 -1.0986 -0.7027 3213086 CHDI2_000038 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B18 compound treatment 154800.0 9830.0 0.3 195080.0 39800.0 1.03 0.9473 0.878 3213128 CHDI2_000039 C/C=C(/C)\C=N\NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B19 compound treatment 142840.0 -2130.0 -0.07 237240.0 82000.0 2.13 1.4598 0.6849 3213090 CHDI2_000040 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B20 compound treatment 108320.0 -36600.0 -1.14 63560.0 -91700.0 -2.38 -2.4875 -0.9426 3213204 CHDI2_000041 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B21 compound treatment 217720.0 72800.0 2.25 214960.0 59700.0 1.55 2.691 0.9834 3213094 CHDI2_000042 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Br)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B22 compound treatment 182280.0 37300.0 1.16 246400.0 91200.0 2.37 2.4922 0.9456 3213136 CHDI2_000043 Cc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B23 mock treatment 196480.0 51500.0 1.6 188760.0 33500.0 0.87 1.7443 0.9594 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 B24 mock treatment 204280.0 59300.0 1.84 232320.0 77100.0 2.0 2.7155 0.9991 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C01 compound treatment 76840.0 -68100.0 -2.11 72160.0 -83100.0 -2.16 -3.0192 -0.9999 3213144 CHDI2_000044 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Br)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C02 compound treatment 16960.0 -128000.0 -3.97 20080.0 -135000.0 -3.51 -5.2879 -0.9982 3213186 CHDI2_000045 Cc1ccsc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C03 compound treatment 8200.0 -137000.0 -4.24 7000.0 -148000.0 -3.85 -5.7202 -0.9989 3213148 CHDI2_000046 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C04 compound treatment 17520.0 -127000.0 -3.95 13160.0 -142000.0 -3.69 -5.4028 -0.9994 3213190 CHDI2_000047 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C05 compound treatment 9680.0 -135000.0 -4.19 7920.0 -147000.0 -3.83 -5.6708 -0.999 3213152 CHDI2_000048 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(O)ccc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C06 compound treatment 7040.0 -138000.0 -4.27 6640.0 -149000.0 -3.86 -5.7522 -0.9987 3213194 CHDI2_000049 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C07 compound treatment 8680.0 -136000.0 -4.22 6640.0 -149000.0 -3.86 -5.7163 -0.999 3213156 CHDI2_000050 COc1cc(Br)cc(/C=N/NC(=O)CCCCCCC(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C08 compound treatment 8760.0 -136000.0 -4.22 7840.0 -147000.0 -3.83 -5.6925 -0.9988 3213202 CHDI2_000051 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2ccccc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C09 compound treatment 10040.0 -135000.0 -4.18 8480.0 -147000.0 -3.81 -5.6527 -0.9989 3213160 CHDI2_000052 COc1ccc(Br)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C10 compound treatment 22400.0 -123000.0 -3.8 18760.0 -136000.0 -3.55 -5.193 -0.9994 3213134 CHDI2_000053 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C11 compound treatment 104040.0 -40900.0 -1.27 85280.0 -70000.0 -1.82 -2.1822 -0.9845 3214262 CHDI2_000054 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C12 compound treatment 74560.0 -70400.0 -2.18 53000.0 -102000.0 -2.66 -3.4211 -0.9952 3214366 CHDI2_000055 ONC(=O)CCCCCC(=O)N/N=C/c1c(F)c(F)c(F)c(F)c1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C13 compound treatment 39240.0 -106000.0 -3.28 36400.0 -119000.0 -3.09 -4.5 -0.9996 3213164 CHDI2_000056 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C14 compound treatment 58600.0 -86400.0 -2.68 46040.0 -109000.0 -2.84 -3.8987 -0.9996 3213198 CHDI2_000057 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C15 compound treatment 135800.0 -9170.0 -0.28 123960.0 -31300.0 -0.81 -0.7757 -0.9008 3214266 CHDI2_000058 ONC(=O)CCCCCC(=O)N/N=C/c1ccc([N+](=O)[O-])c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C16 compound treatment 154000.0 9030.0 0.28 126320.0 -28900.0 -0.75 -0.3336 -0.4159 3214370 CHDI2_000059 ONC(=O)CCCCCC(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C17 compound treatment 30080.0 -115000.0 -3.56 25520.0 -130000.0 -3.37 -4.9005 -0.9996 3213168 CHDI2_000060 ONC(=O)CCCCCCC(=O)N/N=C/c1cc2OCOc2cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C18 compound treatment 17880.0 -127000.0 -3.94 7480.0 -148000.0 -3.84 -5.4993 -0.9999 3213210 CHDI2_000061 ONC(=O)CCCCCCC(=O)N/N=C/c1c(F)c(F)c(F)c(F)c1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C19 compound treatment 26680.0 -118000.0 -3.67 20720.0 -135000.0 -3.5 -5.0632 -0.9997 3213172 CHDI2_000062 ONC(=O)CCCCCCC(=O)N/N=C/c1cccnc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C20 compound treatment 121080.0 -23900.0 -0.74 145280.0 -9970.0 -0.26 -0.7065 -0.901 3213214 CHDI2_000063 ONC(=O)CCCCCCC(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C21 compound treatment 23080.0 -122000.0 -3.78 20120.0 -135000.0 -3.51 -5.1531 -0.9993 3213176 CHDI2_000064 ONC(=O)CCCCCCC(=O)N/N=C/c1ccncc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C22 compound treatment 38320.0 -107000.0 -3.3 32280.0 -123000.0 -3.2 -4.5958 -0.9999 3213218 CHDI2_000065 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C23 mock treatment 175720.0 30800.0 0.95 208160.0 52900.0 1.37 1.6459 0.984 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 C24 mock treatment 190080.0 45100.0 1.4 205680.0 50400.0 1.31 1.915 0.9995 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D01 compound treatment 136240.0 -8730.0 -0.27 151320.0 -3930.0 -0.1 -0.2634 -0.9112 3213146 CHDI2_000066 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Br)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D02 compound treatment 167920.0 23000.0 0.71 146760.0 -8490.0 -0.22 0.3469 0.466 3213184 CHDI2_000067 Cc1ccsc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D03 compound treatment 94840.0 -50100.0 -1.55 77440.0 -77800.0 -2.02 -2.5278 -0.9915 3213150 CHDI2_000068 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D04 compound treatment 143040.0 -1930.0 -0.06 158800.0 3550.0 0.09 0.023 0.2096 3213188 CHDI2_000069 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCCC(=O)Nc3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D05 compound treatment 97760.0 -47200.0 -1.46 90040.0 -65200.0 -1.69 -2.2323 -0.9973 3213154 CHDI2_000070 Oc1ccc(Br)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D06 compound treatment 108920.0 -36000.0 -1.12 97360.0 -57900.0 -1.5 -1.8533 -0.9893 3213192 CHDI2_000071 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D07 compound treatment 109360.0 -35600.0 -1.1 98480.0 -56800.0 -1.47 -1.8231 -0.9898 3213158 CHDI2_000072 COc1cc(Br)cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D08 compound treatment 140560.0 -4410.0 -0.14 178080.0 22800.0 0.59 0.3229 0.5304 3213200 CHDI2_000073 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3ccccc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D09 compound treatment 95560.0 -49400.0 -1.53 74960.0 -80300.0 -2.09 -2.5576 -0.9884 3213162 CHDI2_000074 COc1ccc(Br)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D10 compound treatment 143080.0 -1890.0 -0.06 150880.0 -4370.0 -0.11 -0.1216 -0.9525 3213132 CHDI2_000075 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D11 compound treatment 169600.0 24600.0 0.76 144440.0 -10800.0 -0.28 0.3411 0.4195 3214504 CHDI2_000076 ONC(=O)CCCCCC(=O)N/N=C/c1c(O)cc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D12 mock treatment 146880.0 1910.0 0.06 140440.0 -14800.0 -0.38 -0.2301 -0.5912 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D13 compound treatment 114000.0 -31000.0 -0.96 82600.0 -72600.0 -1.89 -2.0132 -0.9508 3213166 CHDI2_000077 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D14 compound treatment 165320.0 20400.0 0.63 167400.0 12200.0 0.32 0.6692 0.9489 3213196 CHDI2_000078 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D15 compound treatment 151240.0 6270.0 0.19 154240.0 -1010.0 -0.03 0.1189 0.6065 3214508 CHDI2_000079 COc1cc(OC)c(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D16 compound treatment 144760.0 -208.0 -0.01 151920.0 -3330.0 -0.09 -0.0657 -0.7577 3214630 CHDI2_000080 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D17 compound treatment 117840.0 -27100.0 -0.84 72160.0 -83100.0 -2.16 -2.1209 -0.9155 3213170 CHDI2_000081 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D18 compound treatment 23000.0 -122000.0 -3.78 17960.0 -137000.0 -3.57 -5.1946 -0.9996 3213208 CHDI2_000082 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D19 compound treatment 206760.0 61800.0 1.91 149520.0 -5730.0 -0.15 1.2486 0.6502 3213174 CHDI2_000083 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccnc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D20 compound treatment 152800.0 7830.0 0.24 139160.0 -16100.0 -0.42 -0.124 -0.2565 3213212 CHDI2_000084 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D21 compound treatment 165680.0 20700.0 0.64 192280.0 37000.0 0.96 1.1342 0.9806 3213178 CHDI2_000085 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccncc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D22 compound treatment 130680.0 -14300.0 -0.44 201600.0 46400.0 1.2 0.5386 0.4197 3213216 CHDI2_000086 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D23 mock treatment 171960.0 27000.0 0.84 157800.0 2550.0 0.07 0.6383 0.7608 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 D24 mock treatment 165880.0 20900.0 0.65 164400.0 9150.0 0.24 0.6263 0.9075 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E01 compound treatment 152840.0 7870.0 0.24 152240.0 -3010.0 -0.08 0.1172 0.4577 3214270 CHDI2_000087 ONC(=O)CCCCCC(=O)N/N=C/c1cc(O)ccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E02 compound treatment 12640.0 -132000.0 -4.1 12200.0 -143000.0 -3.72 -5.5274 -0.9988 3214374 CHDI2_000088 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E03 compound treatment 7880.0 -137000.0 -4.25 7560.0 -148000.0 -3.84 -5.7169 -0.9987 3213224 CHDI2_000089 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Br)s1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E04 compound treatment 15480.0 -129000.0 -4.01 22520.0 -133000.0 -3.45 -5.2755 -0.9972 3213262 CHDI2_000090 ONC(=O)CCCCCCC(=O)N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E05 compound treatment 16720.0 -128000.0 -3.97 13920.0 -141000.0 -3.67 -5.4064 -0.9992 3213228 CHDI2_000091 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E06 compound treatment 64840.0 -80100.0 -2.48 57840.0 -97400.0 -2.53 -3.5452 -1.0 3213266 CHDI2_000092 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E07 compound treatment 8800.0 -136000.0 -4.22 8560.0 -147000.0 -3.81 -5.6784 -0.9987 3213232 CHDI2_000093 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E08 compound treatment 92160.0 -52800.0 -1.64 73240.0 -82000.0 -2.13 -2.6637 -0.9915 3213270 CHDI2_000094 ONC(=O)CCCCCCC(=O)N/N=C/c1cccnc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E09 compound treatment 138600.0 -6370.0 -0.2 111560.0 -43700.0 -1.14 -0.9422 -0.8178 3214274 CHDI2_000095 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)n2ccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E10 compound treatment 20640.0 -124000.0 -3.85 19600.0 -136000.0 -3.52 -5.2161 -0.999 3214378 CHDI2_000096 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(Oc2ccccc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E11 compound treatment 88840.0 -56100.0 -1.74 88600.0 -66600.0 -1.73 -2.4542 -1.0 3213236 CHDI2_000097 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E12 compound treatment 133680.0 -11300.0 -0.35 169000.0 13800.0 0.36 0.0054 0.0108 3213274 CHDI2_000098 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E13 compound treatment 123160.0 -21800.0 -0.68 164520.0 9270.0 0.24 -0.3074 -0.4285 3213240 CHDI2_000099 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E14 compound treatment 138640.0 -6330.0 -0.2 178360.0 23100.0 0.6 0.286 0.4527 3213278 CHDI2_000100 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E15 compound treatment 21520.0 -123000.0 -3.82 16720.0 -139000.0 -3.6 -5.2498 -0.9995 3213244 CHDI2_000101 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E16 compound treatment 28840.0 -116000.0 -3.6 28360.0 -127000.0 -3.3 -4.8755 -0.999 3213282 CHDI2_000102 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)N2CCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E17 compound treatment 91840.0 -53100.0 -1.65 73320.0 -81900.0 -2.13 -2.6692 -0.9919 3214278 CHDI2_000103 ONC(=O)CCCCCC(=O)N/N=C/c1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E18 compound treatment 11680.0 -133000.0 -4.13 9840.0 -145000.0 -3.78 -5.5917 -0.999 3214418 CHDI2_000104 ONC(=O)CCCCCC(=O)N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E19 compound treatment 141000.0 -3970.0 -0.12 142400.0 -12800.0 -0.33 -0.323 -0.9079 3213248 CHDI2_000105 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E20 compound treatment 59080.0 -85900.0 -2.66 48200.0 -107000.0 -2.78 -3.8485 -0.9998 3213286 CHDI2_000106 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E21 compound treatment 128600.0 -16400.0 -0.51 142440.0 -12800.0 -0.33 -0.5939 -0.9791 3213252 CHDI2_000107 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E22 compound treatment 124520.0 -20400.0 -0.63 135960.0 -19300.0 -0.5 -0.8023 -0.9933 3213290 CHDI2_000108 CCCCCCC/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E23 mock treatment 141000.0 -3970.0 -0.12 182760.0 27500.0 0.71 0.4186 0.577 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 E24 mock treatment 166440.0 21500.0 0.67 150320.0 -4930.0 -0.13 0.3799 0.5608 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F01 compound treatment 165680.0 20700.0 0.64 141160.0 -14100.0 -0.37 0.195 0.2639 3214512 CHDI2_000109 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F02 compound treatment 145800.0 832.0 0.03 143360.0 -11900.0 -0.31 -0.2002 -0.6458 3214634 CHDI2_000110 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F03 compound treatment 129640.0 -15300.0 -0.47 120160.0 -35100.0 -0.91 -0.9805 -0.9538 3213226 CHDI2_000111 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Br)s2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F04 compound treatment 59200.0 -85800.0 -2.66 64000.0 -91200.0 -2.37 -3.5556 -0.9984 3213260 CHDI2_000112 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F05 compound treatment 138920.0 -6050.0 -0.19 143080.0 -12200.0 -0.32 -0.356 -0.9688 3213230 CHDI2_000113 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F06 compound treatment 163720.0 18800.0 0.58 149920.0 -5330.0 -0.14 0.313 0.524 3213264 CHDI2_000114 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F07 compound treatment 69680.0 -75300.0 -2.33 60840.0 -94400.0 -2.45 -3.384 -0.9997 3213234 CHDI2_000115 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F08 compound treatment 122080.0 -22900.0 -0.71 165840.0 10600.0 0.28 -0.3068 -0.4033 3213268 CHDI2_000116 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F09 compound treatment 138920.0 -6050.0 -0.19 143680.0 -11600.0 -0.3 -0.345 -0.9742 3214516 CHDI2_000117 CC(C)(C)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F10 compound treatment 141440.0 -3530.0 -0.11 137280.0 -18000.0 -0.47 -0.4074 -0.8497 3214638 CHDI2_000118 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F11 compound treatment 145040.0 72.0 0.0 155120.0 -126.0 0.0 -7.0E-4 -0.1879 3213238 CHDI2_000119 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F12 compound treatment 160920.0 16000.0 0.49 153800.0 -1450.0 -0.04 0.3229 0.6515 3213272 CHDI2_000120 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F13 compound treatment 128760.0 -16200.0 -0.5 129000.0 -26200.0 -0.68 -0.8373 -0.9887 3213242 CHDI2_000121 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F14 compound treatment 178840.0 33900.0 1.05 170920.0 15700.0 0.41 1.0301 0.915 3213276 CHDI2_000122 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F15 compound treatment 119480.0 -25500.0 -0.79 122080.0 -33200.0 -0.86 -1.1678 -0.9991 3213246 CHDI2_000123 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F16 compound treatment 143920.0 -1050.0 -0.03 131880.0 -23400.0 -0.61 -0.4523 -0.7439 3213280 CHDI2_000124 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F17 compound treatment 127760.0 -17200.0 -0.53 117440.0 -37800.0 -0.98 -1.0716 -0.9588 3214520 CHDI2_000125 CC1=C(C/C=N/NC(=O)CCCCCC(=O)NO)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F18 compound treatment 128080.0 -16900.0 -0.52 140480.0 -14800.0 -0.38 -0.6413 -0.9884 3214641 CHDI2_000126 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F19 compound treatment 144440.0 -528.0 -0.02 128440.0 -26800.0 -0.7 -0.5041 -0.7235 3213250 CHDI2_000127 OC(=O)c1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F20 compound treatment 166720.0 21800.0 0.67 130840.0 -24400.0 -0.63 0.0282 0.0304 3213284 CHDI2_000128 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F21 compound treatment 129280.0 -15700.0 -0.49 141880.0 -13400.0 -0.35 -0.5893 -0.9864 3213254 CHDI2_000129 OC(=O)c1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F22 compound treatment 146520.0 1550.0 0.05 158120.0 2870.0 0.07 0.0868 0.9774 3213288 CHDI2_000130 CCCCCCC/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F23 mock treatment 144760.0 -208.0 -0.01 156200.0 954.0 0.02 0.013 0.5063 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 F24 mock treatment 176240.0 31300.0 0.97 171960.0 16700.0 0.43 0.9922 0.9345 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G01 compound treatment 10960.0 -134000.0 -4.15 9280.0 -146000.0 -3.79 -5.6178 -0.999 3213296 CHDI2_000131 ONC(=O)CCCCCCC(=O)N/N=C/c1ccccc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G02 compound treatment 19480.0 -125000.0 -3.89 20520.0 -135000.0 -3.5 -5.2246 -0.9986 3213336 CHDI2_000132 ONC(=O)CCCCCCC(=O)N/N=C/c1cccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G03 compound treatment 8360.0 -137000.0 -4.23 9440.0 -146000.0 -3.79 -5.6718 -0.9985 3214282 CHDI2_000133 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(I)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G04 compound treatment 99320.0 -45600.0 -1.41 91400.0 -63800.0 -1.66 -2.1731 -0.9968 3214422 CHDI2_000134 ONC(=O)CCCCCC(=O)N/N=C/c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G05 compound treatment 21760.0 -123000.0 -3.82 22160.0 -133000.0 -3.46 -5.1446 -0.9988 3213300 CHDI2_000135 ONC(=O)CCCCCCC(=O)N/N=C/c1cccnc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G06 compound treatment 10760.0 -134000.0 -4.16 11800.0 -143000.0 -3.73 -5.5759 -0.9985 3213340 CHDI2_000136 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G07 compound treatment 13720.0 -131000.0 -4.07 12960.0 -142000.0 -3.7 -5.4897 -0.9989 3213304 CHDI2_000137 ONC(=O)CCCCCCC(=O)N/N=C/C=C/c1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G08 compound treatment 177280.0 32300.0 1.0 146960.0 -8290.0 -0.22 0.5557 0.5426 3213344 CHDI2_000138 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G09 compound treatment 128960.0 -16000.0 -0.5 110160.0 -45100.0 -1.17 -1.1791 -0.9268 3213308 CHDI2_000139 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G10 compound treatment 154640.0 9670.0 0.3 148080.0 -7170.0 -0.19 0.0802 0.2274 3213348 CHDI2_000140 ONC(=O)CCCCCCC(=O)N/N=C/c1c(O)cc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G11 compound treatment 131040.0 -13900.0 -0.43 132680.0 -22600.0 -0.59 -0.7198 -0.9886 3213312 CHDI2_000141 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G12 compound treatment 127600.0 -17400.0 -0.54 122360.0 -32900.0 -0.85 -0.9847 -0.9752 3213352 CHDI2_000142 COc1cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G13 compound treatment 27080.0 -118000.0 -3.65 29320.0 -126000.0 -3.27 -4.8964 -0.9985 3213314 CHDI2_000143 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(C#N)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G14 compound treatment 123400.0 -21600.0 -0.67 119040.0 -36200.0 -0.94 -1.1377 -0.986 3213356 CHDI2_000144 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G15 compound treatment 139600.0 -5370.0 -0.17 130680.0 -24600.0 -0.64 -0.569 -0.8626 3213318 CHDI2_000145 ONC(=O)CCCCCCC(=O)N/N=C/C1CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G16 compound treatment 136160.0 -8810.0 -0.27 120200.0 -35000.0 -0.91 -0.8369 -0.8803 3213360 CHDI2_000146 CC(C)(C)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G17 compound treatment 23120.0 -122000.0 -3.78 20400.0 -135000.0 -3.5 -5.1471 -0.9993 3213322 CHDI2_000147 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G18 compound treatment 110000.0 -35000.0 -1.08 91400.0 -63800.0 -1.66 -1.9392 -0.9787 3213364 CHDI2_000148 CC1=C(C/C=N/NC(=O)CCCCCCC(=O)NO)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G19 compound treatment 137440.0 -7530.0 -0.23 133640.0 -21600.0 -0.56 -0.5619 -0.9243 3214286 CHDI2_000149 C/C=C(/C)\C=N\NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G20 compound treatment 128840.0 -16100.0 -0.5 116840.0 -38400.0 -1.0 -1.059 -0.9489 3214426 CHDI2_000150 ONC(=O)CCCCCC(=O)N/N=C/c1cccnc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G21 compound treatment 11560.0 -133000.0 -4.13 11560.0 -144000.0 -3.73 -5.5628 -0.9987 3213326 CHDI2_000151 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)cc(Br)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G22 compound treatment 127880.0 -17100.0 -0.53 133360.0 -21900.0 -0.57 -0.7765 -0.9994 3213368 CHDI2_000152 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G23 mock treatment 126520.0 -18400.0 -0.57 153200.0 -2050.0 -0.05 -0.4418 -0.7696 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 G24 mock treatment 178440.0 33500.0 1.04 161400.0 6150.0 0.16 0.8464 0.8066 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H01 compound treatment 125000.0 -20000.0 -0.62 117920.0 -37300.0 -0.97 -1.1233 -0.9764 3213298 CHDI2_000153 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccccc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H02 compound treatment 157480.0 12500.0 0.39 153760.0 -1490.0 -0.04 0.2468 0.6335 3213334 CHDI2_000154 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H03 compound treatment 133680.0 -11300.0 -0.35 140720.0 -14500.0 -0.38 -0.5142 -0.9993 3214524 CHDI2_000155 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H04 compound treatment 167160.0 22200.0 0.69 140120.0 -15100.0 -0.39 0.2083 0.263 3214643 CHDI2_000156 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H05 compound treatment 160120.0 15200.0 0.47 165280.0 10000.0 0.26 0.5163 0.9615 3213302 CHDI2_000157 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccnc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H06 compound treatment 167720.0 22800.0 0.7 152800.0 -2450.0 -0.06 0.4535 0.6407 3213338 CHDI2_000158 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H07 compound treatment 135680.0 -9290.0 -0.29 154240.0 -1010.0 -0.03 -0.222 -0.7682 3213306 CHDI2_000159 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H08 compound treatment 203640.0 58700.0 1.82 203000.0 47800.0 1.24 2.1628 0.9827 3213342 CHDI2_000160 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H09 compound treatment 144920.0 -48.0 0.0 132840.0 -22400.0 -0.58 -0.4127 -0.7089 3213310 CHDI2_000161 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H10 compound treatment 159440.0 14500.0 0.45 160040.0 4790.0 0.12 0.4051 0.8706 3213346 CHDI2_000162 Oc1cc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H11 compound treatment 113600.0 -31400.0 -0.97 125480.0 -29800.0 -0.77 -1.2341 -0.9936 3213313 CHDI2_000163 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H12 compound treatment 146680.0 1710.0 0.05 135680.0 -19600.0 -0.51 -0.322 -0.6299 3213350 CHDI2_000164 COc1cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H13 compound treatment 134360.0 -10600.0 -0.33 128440.0 -26800.0 -0.7 -0.7249 -0.9413 3213316 CHDI2_000165 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(C#N)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H14 compound treatment 143520.0 -1450.0 -0.04 147960.0 -7290.0 -0.19 -0.1656 -0.8511 3213354 CHDI2_000166 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H15 compound treatment 133080.0 -11900.0 -0.37 140200.0 -15000.0 -0.39 -0.5369 -0.9996 3213320 CHDI2_000167 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H16 compound treatment 126600.0 -18400.0 -0.57 125160.0 -30100.0 -0.78 -0.9552 -0.9878 3213358 CHDI2_000168 CC(C)(C)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H17 compound treatment 152960.0 7990.0 0.25 161280.0 6030.0 0.16 0.286 0.9757 3213324 CHDI2_000169 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H18 compound treatment 123280.0 -21700.0 -0.67 123720.0 -31500.0 -0.82 -1.0544 -0.9952 3213362 CHDI2_000170 CC1=C(C/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H19 compound treatment 143320.0 -1650.0 -0.05 142840.0 -12400.0 -0.32 -0.264 -0.809 3214528 CHDI2_000171 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H20 compound treatment 131680.0 -13300.0 -0.41 135600.0 -19600.0 -0.51 -0.6521 -0.9943 3214646 CHDI2_000172 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H21 compound treatment 21280.0 -124000.0 -3.83 21720.0 -134000.0 -3.47 -5.1632 -0.9988 3213328 CHDI2_000173 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H22 compound treatment 136480.0 -8490.0 -0.26 149760.0 -5490.0 -0.14 -0.2868 -0.9586 3213366 CHDI2_000174 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H23 mock treatment 135640.0 -9330.0 -0.29 136440.0 -18800.0 -0.49 -0.5499 -0.9686 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 H24 mock treatment 139480.0 -5490.0 -0.17 190360.0 35100.0 0.91 0.5249 0.5656 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I01 compound treatment 8000.0 -137000.0 -4.24 9520.0 -146000.0 -3.79 -5.6783 -0.9984 3213374 CHDI2_000175 COc1cc(Cl)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I02 compound treatment 143240.0 -1730.0 -0.05 134160.0 -21100.0 -0.55 -0.4253 -0.7725 3213415 CHDI2_000176 ONC(=O)CCCCCCC(=O)NN=C1CCCCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I03 compound treatment 10480.0 -134000.0 -4.17 11680.0 -144000.0 -3.73 -5.5842 -0.9985 3213378 CHDI2_000177 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Cl)cc(Cl)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I04 compound treatment 125360.0 -19600.0 -0.61 142760.0 -12500.0 -0.32 -0.659 -0.9568 3213417 CHDI2_000178 ONC(=O)CCCCCCC(=O)NN=C1CCCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I05 compound treatment 11000.0 -134000.0 -4.15 11160.0 -144000.0 -3.74 -5.5824 -0.9987 3214362 CHDI2_000179 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(s1)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I06 compound treatment 125760.0 -19200.0 -0.6 128840.0 -26400.0 -0.69 -0.906 -0.9975 3214430 CHDI2_000180 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCC(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I07 compound treatment 113080.0 -31900.0 -0.99 135800.0 -19400.0 -0.51 -1.0559 -0.9515 3213382 CHDI2_000181 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)cc([N+](=O)[O-])c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I08 compound treatment 132360.0 -12600.0 -0.39 132560.0 -22700.0 -0.59 -0.693 -0.98 3213419 CHDI2_000182 ONC(=O)CCCCCCC(=O)NN=C1CCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I09 compound treatment 11880.0 -133000.0 -4.12 12200.0 -143000.0 -3.72 -5.544 -0.9987 3213386 CHDI2_000183 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I10 mock treatment 107600.0 -37400.0 -1.16 129000.0 -26200.0 -0.68 -1.3009 -0.9681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I11 compound treatment 14720.0 -130000.0 -4.04 14720.0 -141000.0 -3.65 -5.4355 -0.9988 3213390 CHDI2_000184 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2OCCc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I12 compound treatment 12640.0 -132000.0 -4.1 12960.0 -142000.0 -3.7 -5.5134 -0.9987 3213422 CHDI2_000185 COc1cc(Br)c(/C=N/NC(=O)CCCCCCC(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I13 compound treatment 73360.0 -71600.0 -2.22 77480.0 -77800.0 -2.02 -2.9977 -0.9989 3213394 CHDI2_000186 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I14 compound treatment 125000.0 -20000.0 -0.62 140480.0 -14800.0 -0.38 -0.7088 -0.9736 3213426 CHDI2_000187 ONC(=O)CCCCCCC(=O)N/N=C/CCC1CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I15 compound treatment 122160.0 -22800.0 -0.71 114800.0 -40400.0 -1.05 -1.2428 -0.9814 3213398 CHDI2_000188 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I16 compound treatment 10920.0 -134000.0 -4.15 11800.0 -143000.0 -3.73 -5.5724 -0.9985 3213430 CHDI2_000189 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I17 compound treatment 132720.0 -12200.0 -0.38 146920.0 -8330.0 -0.22 -0.4213 -0.9645 3213402 CHDI2_000190 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I18 compound treatment 119440.0 -25500.0 -0.79 134720.0 -20500.0 -0.53 -0.9364 -0.9816 3213434 CHDI2_000191 ONC(=O)CCCCCCC(=O)N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I19 compound treatment 121520.0 -23400.0 -0.73 124040.0 -31200.0 -0.81 -1.0871 -0.9985 3213406 CHDI2_000192 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I20 mock treatment 140960.0 -4010.0 -0.12 136880.0 -18400.0 -0.48 -0.4253 -0.8624 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I21 compound treatment 106280.0 -38700.0 -1.2 97720.0 -57500.0 -1.49 -1.9045 -0.994 3214294 CHDI2_000193 Cc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I22 compound treatment 153560.0 8590.0 0.27 139120.0 -16100.0 -0.42 -0.108 -0.2176 3214434 CHDI2_000194 ONC(=O)CCCCCC(=O)N/N=C/c1ccc[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I23 mock treatment 130920.0 -14000.0 -0.44 141360.0 -13900.0 -0.36 -0.5629 -0.9957 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 I24 mock treatment 148400.0 3430.0 0.11 150080.0 -5170.0 -0.13 -0.0197 -0.1152 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J01 compound treatment 121800.0 -23200.0 -0.72 182160.0 26900.0 0.7 -0.0131 -0.0131 3213376 CHDI2_000195 COc1cc(Cl)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J02 compound treatment 146760.0 1790.0 0.06 149920.0 -5330.0 -0.14 -0.0586 -0.393 3213414 CHDI2_000196 Oc1ccccc1NC(=O)CCCCCCC(=O)NN=C2CCCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J03 compound treatment 57720.0 -87200.0 -2.7 81480.0 -73800.0 -1.92 -3.2668 -0.9858 3213380 CHDI2_000197 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J04 compound treatment 148280.0 3310.0 0.1 140400.0 -14800.0 -0.39 -0.2002 -0.5016 3213416 CHDI2_000198 Oc1ccccc1NC(=O)CCCCCCC(=O)NN=C2CCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J05 compound treatment 122720.0 -22200.0 -0.69 128040.0 -27200.0 -0.71 -0.9873 -0.9999 3214571 CHDI2_000199 ONC(=O)CCCCCC(=O)NN=C1CCCCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J06 compound treatment 11600.0 -133000.0 -4.13 13520.0 -142000.0 -3.68 -5.5259 -0.9983 3214650 CHDI2_000200 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Oc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J07 compound treatment 118560.0 -26400.0 -0.82 118520.0 -36700.0 -0.95 -1.2533 -0.9971 3213384 CHDI2_000201 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J08 compound treatment 138480.0 -6490.0 -0.2 133520.0 -21700.0 -0.56 -0.5413 -0.9033 3213418 CHDI2_000202 Oc1ccccc1NC(=O)CCCCCCC(=O)NN=C2CCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J09 compound treatment 73440.0 -71500.0 -2.22 88680.0 -66600.0 -1.73 -2.7901 -0.9925 3213388 CHDI2_000203 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J10 mock treatment 105840.0 -39100.0 -1.21 166400.0 11200.0 0.29 -0.6523 -0.5233 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J11 compound treatment 137600.0 -7370.0 -0.23 133200.0 -22000.0 -0.57 -0.5665 -0.9186 3213392 CHDI2_000204 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3OCCc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J12 compound treatment 131960.0 -13000.0 -0.4 159680.0 4430.0 0.12 -0.2035 -0.4856 3213420 CHDI2_000205 COc1cc(Br)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J13 compound treatment 85680.0 -59300.0 -1.84 94040.0 -61200.0 -1.59 -2.4235 -0.9974 3213396 CHDI2_000206 Oc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J14 compound treatment 136000.0 -8970.0 -0.28 147920.0 -7330.0 -0.19 -0.3311 -0.983 3213424 CHDI2_000207 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/CCC2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J15 compound treatment 54200.0 -90800.0 -2.81 54000.0 -101000.0 -2.63 -3.8488 -0.9994 3213400 CHDI2_000208 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J16 compound treatment 122800.0 -22200.0 -0.69 119400.0 -35800.0 -0.93 -1.1443 -0.9888 3213428 CHDI2_000209 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J17 compound treatment 146280.0 1310.0 0.04 157040.0 1790.0 0.05 0.0617 0.9977 3213404 CHDI2_000210 Oc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J18 compound treatment 132920.0 -12000.0 -0.37 154600.0 -646.0 -0.02 -0.2758 -0.7382 3213432 CHDI2_000211 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J19 compound treatment 116400.0 -28600.0 -0.89 120720.0 -34500.0 -0.9 -1.2602 -1.0 3213408 CHDI2_000212 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J20 mock treatment 118560.0 -26400.0 -0.82 136280.0 -19000.0 -0.49 -0.927 -0.9705 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J21 compound treatment 135920.0 -9050.0 -0.28 135280.0 -20000.0 -0.52 -0.5651 -0.9583 3214573 CHDI2_000213 ONC(=O)CCCCCC(=O)NN=C1CCCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J22 compound treatment 129280.0 -15700.0 -0.49 134720.0 -20500.0 -0.53 -0.7208 -0.9989 3214654 CHDI2_000214 ONC(=O)CCCCCC(=O)N/N=C/c1cc[n+]([O-])cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J23 mock treatment 134800.0 -10200.0 -0.32 119360.0 -35900.0 -0.93 -0.8821 -0.8962 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 J24 mock treatment 122080.0 -22900.0 -0.71 188880.0 33600.0 0.87 0.1165 0.1035 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K01 compound treatment 61360.0 -83600.0 -2.59 101440.0 -53800.0 -1.4 -2.8204 -0.9581 3213436 CHDI2_000215 COc1cccc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K02 compound treatment 138040.0 -6930.0 -0.21 129960.0 -25300.0 -0.66 -0.6164 -0.8917 3213474 CHDI2_000216 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K03 compound treatment 60760.0 -84200.0 -2.61 77600.0 -77600.0 -2.02 -3.2715 -0.9919 3213440 CHDI2_000217 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K04 compound treatment 123320.0 -21600.0 -0.67 138480.0 -16800.0 -0.44 -0.7823 -0.9782 3213478 CHDI2_000218 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K05 compound treatment 124000.0 -21000.0 -0.65 137560.0 -17700.0 -0.46 -0.7843 -0.9856 3213444 CHDI2_000219 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K06 compound treatment 129080.0 -15900.0 -0.49 146480.0 -8770.0 -0.23 -0.5092 -0.9387 3213482 CHDI2_000220 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K07 compound treatment 115040.0 -29900.0 -0.93 125200.0 -30000.0 -0.78 -1.2077 -0.9963 3214298 CHDI2_000221 Cc1[nH]cnc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K08 compound treatment 23600.0 -121000.0 -3.76 26480.0 -129000.0 -3.35 -5.0249 -0.9983 3214438 CHDI2_000222 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)N2CCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K09 compound treatment 128560.0 -16400.0 -0.51 132480.0 -22800.0 -0.59 -0.7778 -0.9972 3213448 CHDI2_000223 CC1(C)COC(CCC/C=N/NC(=O)CCCCCCC(=O)NO)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K10 compound treatment 132920.0 -12000.0 -0.37 129040.0 -26200.0 -0.68 -0.7454 -0.96 3213485 CHDI2_000224 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K11 compound treatment 117040.0 -27900.0 -0.87 128280.0 -27000.0 -0.7 -1.1073 -0.9945 3213452 CHDI2_000225 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K12 compound treatment 116760.0 -28200.0 -0.87 125280.0 -30000.0 -0.78 -1.1686 -0.9983 3213487 CHDI2_000226 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K13 compound treatment 10440.0 -135000.0 -4.17 11400.0 -144000.0 -3.74 -5.5903 -0.9985 3213456 CHDI2_000227 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)cs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K14 compound treatment 125200.0 -19800.0 -0.61 114880.0 -40400.0 -1.05 -1.1747 -0.9672 3213490 CHDI2_000228 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K15 compound treatment 32880.0 -112000.0 -3.47 30360.0 -125000.0 -3.24 -4.7503 -0.9994 3214342 CHDI2_000229 Cc1ccsc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K16 compound treatment 61360.0 -83600.0 -2.59 77120.0 -78100.0 -2.03 -3.2672 -0.9927 3214442 CHDI2_000230 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K17 compound treatment 114040.0 -30900.0 -0.96 128360.0 -26900.0 -0.7 -1.1716 -0.9879 3213460 CHDI2_000231 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K18 compound treatment 9160.0 -136000.0 -4.21 12320.0 -143000.0 -3.71 -5.6014 -0.9981 3213494 CHDI2_000232 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(Oc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K19 compound treatment 9440.0 -136000.0 -4.2 10520.0 -145000.0 -3.76 -5.6283 -0.9985 3213464 CHDI2_000233 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc-2c(Cc3ccccc32)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K20 compound treatment 138080.0 -6890.0 -0.21 105240.0 -50000.0 -1.3 -1.0697 -0.8124 3213498 CHDI2_000234 ONC(=O)CCCCCCC(=O)N/N=C/c1cc[n+]([O-])cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K21 compound treatment 22760.0 -122000.0 -3.79 16280.0 -139000.0 -3.61 -5.2307 -0.9997 3213468 CHDI2_000235 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(F)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K22 compound treatment 9640.0 -135000.0 -4.19 9920.0 -145000.0 -3.78 -5.635 -0.9986 3213502 CHDI2_000236 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2ccccc2n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K23 mock treatment 130640.0 -14300.0 -0.44 126320.0 -28900.0 -0.75 -0.8454 -0.9684 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 K24 mock treatment 160840.0 15900.0 0.49 173160.0 17900.0 0.47 0.6769 0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L01 compound treatment 104000.0 -41000.0 -1.27 170440.0 15200.0 0.39 -0.6184 -0.4652 3213438 CHDI2_000237 COc1cccc(OC)c1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L02 compound treatment 135320.0 -9650.0 -0.3 140480.0 -14800.0 -0.38 -0.4827 -0.9924 3213472 CHDI2_000238 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L03 compound treatment 122680.0 -22300.0 -0.69 139560.0 -15700.0 -0.41 -0.7765 -0.9684 3213442 CHDI2_000239 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L04 compound treatment 140040.0 -4930.0 -0.15 140880.0 -14400.0 -0.37 -0.3719 -0.9222 3213476 CHDI2_000240 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L05 compound treatment 151360.0 6390.0 0.2 153040.0 -2210.0 -0.06 0.0995 0.4826 3213446 CHDI2_000241 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L06 compound treatment 138280.0 -6690.0 -0.21 152000.0 -3250.0 -0.08 -0.2062 -0.9215 3213480 CHDI2_000242 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L07 compound treatment 86040.0 -58900.0 -1.83 99040.0 -56200.0 -1.46 -2.3237 -0.9939 3214575 CHDI2_000243 ONC(=O)CCCCCC(=O)NN=C1CCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L08 compound treatment 14560.0 -130000.0 -4.04 13200.0 -142000.0 -3.69 -5.4669 -0.999 3214658 CHDI2_000244 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2ccccc2n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L09 compound treatment 125560.0 -19400.0 -0.6 145880.0 -9370.0 -0.24 -0.5973 -0.9207 3213450 CHDI2_000245 CC1(C)COC(CCC/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L10 compound treatment 128840.0 -16100.0 -0.5 126280.0 -29000.0 -0.75 -0.8855 -0.9802 3213484 CHDI2_000246 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L11 compound treatment 122800.0 -22200.0 -0.69 124240.0 -31000.0 -0.81 -1.0554 -0.9968 3213454 CHDI2_000247 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCCC(=O)Nc3ccccc3O)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L12 compound treatment 101360.0 -43600.0 -1.35 133960.0 -21300.0 -0.55 -1.3465 -0.9223 3213486 CHDI2_000248 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L13 compound treatment 109360.0 -35600.0 -1.1 122480.0 -32800.0 -0.85 -1.3822 -0.9918 3213458 CHDI2_000249 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)cs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L14 compound treatment 111720.0 -33200.0 -1.03 119200.0 -36000.0 -0.94 -1.3907 -0.9989 3213488 CHDI2_000250 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L15 mock treatment 109720.0 -35200.0 -1.09 123000.0 -32200.0 -0.84 -1.3647 -0.9914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L16 compound treatment 44640.0 -100000.0 -3.11 51680.0 -104000.0 -2.69 -4.1009 -0.9974 3214702 CHDI2_000251 Cc1ccccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L17 compound treatment 142800.0 -2170.0 -0.07 122840.0 -32400.0 -0.84 -0.6429 -0.7611 3213462 CHDI2_000252 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L18 compound treatment 121520.0 -23400.0 -0.73 128520.0 -26700.0 -0.69 -1.0048 -0.9997 3213492 CHDI2_000253 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L19 compound treatment 121960.0 -23000.0 -0.71 133800.0 -21400.0 -0.56 -0.8981 -0.9926 3213466 CHDI2_000254 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L20 compound treatment 125240.0 -19700.0 -0.61 121240.0 -34000.0 -0.88 -1.057 -0.9838 3213496 CHDI2_000255 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L21 compound treatment 110280.0 -34700.0 -1.07 134200.0 -21000.0 -0.55 -1.1467 -0.9509 3213470 CHDI2_000256 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(F)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L22 compound treatment 82440.0 -62500.0 -1.94 85760.0 -69500.0 -1.81 -2.6466 -0.9994 3213500 CHDI2_000257 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3ccccc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L23 mock treatment 136200.0 -8770.0 -0.27 131680.0 -23600.0 -0.61 -0.6251 -0.9331 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 L24 mock treatment 177040.0 32100.0 0.99 157200.0 1950.0 0.05 0.7386 0.7423 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M01 compound treatment 70320.0 -74600.0 -2.31 111640.0 -43600.0 -1.13 -2.4367 -0.9461 3213504 CHDI2_000258 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M02 compound treatment 11040.0 -134000.0 -4.15 15560.0 -140000.0 -3.63 -5.5007 -0.9978 3213546 CHDI2_000259 Cc1ccccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M03 compound treatment 7080.0 -138000.0 -4.27 10520.0 -145000.0 -3.76 -5.68 -0.998 3213508 CHDI2_000260 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(F)c(Oc2ccccc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M04 compound treatment 76360.0 -68600.0 -2.13 99160.0 -56100.0 -1.46 -2.5336 -0.983 3213550 CHDI2_000261 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M05 compound treatment 14560.0 -130000.0 -4.04 21560.0 -134000.0 -3.47 -5.3133 -0.9972 3213512 CHDI2_000262 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(F)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M06 compound treatment 114880.0 -30100.0 -0.93 135480.0 -19800.0 -0.51 -1.0224 -0.9605 3213554 CHDI2_000263 ONC(=O)CCCCCCC(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M07 compound treatment 115400.0 -29600.0 -0.92 142840.0 -12400.0 -0.32 -0.8758 -0.9017 3213516 CHDI2_000264 ONC(=O)CCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M08 compound treatment 132600.0 -12400.0 -0.38 127120.0 -28100.0 -0.73 -0.7877 -0.9546 3213557 CHDI2_000265 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M09 compound treatment 10600.0 -134000.0 -4.16 11760.0 -143000.0 -3.73 -5.5801 -0.9985 3214350 CHDI2_000266 ONC(=O)CCCCCC(=O)N/N=C/c1cccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M10 compound treatment 80960.0 -64000.0 -1.98 91440.0 -63800.0 -1.66 -2.5747 -0.996 3214450 CHDI2_000267 ONC(=O)CCCCCC(=O)N/N=C/c1nccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M11 compound treatment 11160.0 -134000.0 -4.15 14440.0 -141000.0 -3.66 -5.5186 -0.9981 3213520 CHDI2_000268 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M12 compound treatment 85280.0 -59700.0 -1.85 85320.0 -69900.0 -1.82 -2.5925 -1.0 3213560 CHDI2_000269 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M13 compound treatment 7760.0 -137000.0 -4.25 9240.0 -146000.0 -3.79 -5.6887 -0.9984 3214358 CHDI2_000270 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2ccccc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M14 compound treatment 53080.0 -91900.0 -2.85 57080.0 -98200.0 -2.55 -3.8168 -0.9985 3214492 CHDI2_000271 ONC(=O)CCCCCC(=O)N/N=C/c1cccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M15 compound treatment 122240.0 -22700.0 -0.7 127360.0 -27900.0 -0.72 -1.0103 -0.9999 3213524 CHDI2_000272 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(c1)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M16 compound treatment 9880.0 -135000.0 -4.19 12720.0 -143000.0 -3.7 -5.5783 -0.9981 3213564 CHDI2_000273 CCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)NO)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M17 compound treatment 51920.0 -93000.0 -2.88 70720.0 -84500.0 -2.2 -3.5916 -0.991 3213528 CHDI2_000274 ONC(=O)CCCCCCC(=O)N/N=C/c1ccco1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M18 compound treatment 13960.0 -131000.0 -4.06 18240.0 -137000.0 -3.56 -5.3875 -0.9979 3213568 CHDI2_000275 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(I)cc(I)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M19 compound treatment 81240.0 -63700.0 -1.97 84600.0 -70600.0 -1.84 -2.6942 -0.9993 3213532 CHDI2_000276 ONC(=O)CCCCCCC(=O)N/N=C/c1ccoc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M20 compound treatment 67800.0 -77200.0 -2.39 75680.0 -79600.0 -2.07 -3.1525 -0.9974 3213572 CHDI2_000277 CN(C)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M21 compound treatment 46800.0 -98200.0 -3.04 65000.0 -90200.0 -2.34 -3.8089 -0.9917 3213536 CHDI2_000278 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M22 compound treatment 8120.0 -137000.0 -4.24 8880.0 -146000.0 -3.8 -5.6874 -0.9985 3213576 CHDI2_000279 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M23 mock treatment 131160.0 -13800.0 -0.43 120320.0 -34900.0 -0.91 -0.9442 -0.9411 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 M24 mock treatment 169080.0 24100.0 0.75 166560.0 11300.0 0.29 0.7361 0.9169 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N01 compound treatment 113160.0 -31800.0 -0.99 210200.0 55000.0 1.43 0.3127 0.1803 3213506 CHDI2_000280 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N02 compound treatment 111600.0 -33400.0 -1.03 174680.0 19400.0 0.5 -0.374 -0.3251 3213544 CHDI2_000281 Cc1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N03 compound treatment 98760.0 -46200.0 -1.43 186680.0 31400.0 0.82 -0.4349 -0.2638 3213510 CHDI2_000282 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N04 compound treatment 126240.0 -18700.0 -0.58 130920.0 -24300.0 -0.63 -0.8573 -0.9991 3213548 CHDI2_000283 COc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N05 compound treatment 119600.0 -25400.0 -0.79 163640.0 8390.0 0.22 -0.4016 -0.4923 3213514 CHDI2_000284 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(F)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N06 compound treatment 145040.0 72.0 0.0 146600.0 -8650.0 -0.22 -0.1573 -0.7001 3213552 CHDI2_000285 O[C@@H](/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N07 compound treatment 102560.0 -42400.0 -1.31 143880.0 -11400.0 -0.3 -1.138 -0.845 3213518 CHDI2_000286 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N08 compound treatment 130160.0 -14800.0 -0.46 140000.0 -15200.0 -0.4 -0.6046 -0.9973 3213556 CHDI2_000287 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N09 compound treatment 95000.0 -50000.0 -1.55 127600.0 -27600.0 -0.72 -1.6027 -0.939 3214582 CHDI2_000288 ONC(=O)CCCCCC(=O)N/N=C/CCC1CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N10 compound treatment 114440.0 -30500.0 -0.95 146360.0 -8890.0 -0.23 -0.8321 -0.8546 3214710 CHDI2_000289 ONC(=O)CCCCCC(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N11 compound treatment 70320.0 -74600.0 -2.31 70080.0 -85200.0 -2.21 -3.2002 -0.9998 3213522 CHDI2_000290 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N12 compound treatment 121360.0 -23600.0 -0.73 122680.0 -32600.0 -0.85 -1.1156 -0.9974 3213558 CHDI2_000291 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N13 compound treatment 7240.0 -138000.0 -4.27 8000.0 -147000.0 -3.83 -5.7228 -0.9985 3214586 CHDI2_000292 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N14 compound treatment 106760.0 -38200.0 -1.18 143720.0 -11500.0 -0.3 -1.0489 -0.8589 3214713 CHDI2_000293 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N15 compound treatment 120480.0 -24500.0 -0.76 124680.0 -30600.0 -0.79 -1.0981 -0.9997 3213526 CHDI2_000294 OB(O)c1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N16 compound treatment 129920.0 -15000.0 -0.47 134920.0 -20300.0 -0.53 -0.7031 -0.9981 3213562 CHDI2_000295 CCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N17 compound treatment 124360.0 -20600.0 -0.64 122840.0 -32400.0 -0.84 -1.0469 -0.9907 3213530 CHDI2_000296 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccco2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N18 compound treatment 18560.0 -126000.0 -3.92 13560.0 -142000.0 -3.68 -5.3727 -0.9995 3213566 CHDI2_000297 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N19 compound treatment 132440.0 -12500.0 -0.39 133880.0 -21400.0 -0.56 -0.667 -0.9847 3213534 CHDI2_000298 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccoc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N20 compound treatment 150880.0 5910.0 0.18 136880.0 -18400.0 -0.48 -0.2079 -0.4067 3213570 CHDI2_000299 CN(C)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N21 compound treatment 115200.0 -29800.0 -0.92 118880.0 -36400.0 -0.94 -1.3203 -0.9999 3213538 CHDI2_000300 Oc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N22 compound treatment 113920.0 -31000.0 -0.96 142120.0 -13100.0 -0.34 -0.9214 -0.9027 3213574 CHDI2_000301 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCCC(=O)Nc4ccccc4O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N23 mock treatment 143720.0 -1250.0 -0.04 115280.0 -40000.0 -1.04 -0.7616 -0.7329 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 N24 mock treatment 201440.0 56500.0 1.75 170520.0 15300.0 0.4 1.5179 0.846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O01 compound treatment 38120.0 -107000.0 -3.31 74000.0 -81200.0 -2.11 -3.8337 -0.9764 3213582 CHDI2_000302 OCCOc1ccccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O02 compound treatment 130880.0 -14100.0 -0.44 149440.0 -5810.0 -0.15 -0.4153 -0.8993 3213628 CHDI2_000303 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(o1)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O03 compound treatment 37720.0 -107000.0 -3.32 88000.0 -67200.0 -1.75 -3.5852 -0.9549 3213586 CHDI2_000304 OCCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O04 compound treatment 15440.0 -130000.0 -4.01 16720.0 -139000.0 -3.6 -5.383 -0.9985 3213632 CHDI2_000305 Cn1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O05 compound treatment 33520.0 -111000.0 -3.45 62800.0 -92400.0 -2.4 -4.1402 -0.9843 3213590 CHDI2_000306 OCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O06 compound treatment 6320.0 -139000.0 -4.3 7840.0 -147000.0 -3.83 -5.7459 -0.9984 3213636 CHDI2_000307 ONC(=O)CCCCCCC(=O)N/N=C/c1cn(Cc2ccccc2)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O07 compound treatment 22240.0 -123000.0 -3.8 20080.0 -135000.0 -3.51 -5.1723 -0.9992 3213594 CHDI2_000308 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O08 compound treatment 20560.0 -124000.0 -3.85 20600.0 -135000.0 -3.5 -5.1995 -0.9988 3213640 CHDI2_000309 ONC(=O)CCCCCCC(=O)N/N=C/C1=CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O09 compound treatment 14480.0 -130000.0 -4.04 14360.0 -141000.0 -3.66 -5.4474 -0.9988 3213598 CHDI2_000310 COc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O10 compound treatment 94160.0 -50800.0 -1.57 125040.0 -30200.0 -0.78 -1.6681 -0.9483 3213643 CHDI2_000311 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O11 compound treatment 40160.0 -105000.0 -3.25 57800.0 -97400.0 -2.53 -4.0866 -0.9924 3214290 CHDI2_000312 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O12 compound treatment 15040.0 -130000.0 -4.03 19240.0 -136000.0 -3.53 -5.3454 -0.9979 3214496 CHDI2_000313 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O13 compound treatment 29280.0 -116000.0 -3.58 45480.0 -110000.0 -2.85 -4.5513 -0.9936 3213602 CHDI2_000314 COc1cc(/C=C/C=N/NC(=O)CCCCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O14 compound treatment 100080.0 -44900.0 -1.39 110960.0 -44300.0 -1.15 -1.7971 -0.9956 3213646 CHDI2_000315 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O15 compound treatment 8520.0 -136000.0 -4.23 10360.0 -145000.0 -3.76 -5.6514 -0.9983 3213606 CHDI2_000316 Cc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O16 compound treatment 114440.0 -30500.0 -0.95 108360.0 -46900.0 -1.22 -1.5303 -0.9922 3213650 CHDI2_000317 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O17 compound treatment 81360.0 -63600.0 -1.97 123520.0 -31700.0 -0.82 -1.9765 -0.9252 3213610 CHDI2_000318 OCc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O18 compound treatment 101760.0 -43200.0 -1.34 140520.0 -14700.0 -0.38 -1.2172 -0.8742 3213654 CHDI2_000319 C/C(=N\NC(=O)CCCCCCC(=O)NO)/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O19 compound treatment 6560.0 -138000.0 -4.29 8160.0 -147000.0 -3.82 -5.7348 -0.9983 3213614 CHDI2_000320 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc2ccccc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O20 compound treatment 94360.0 -50600.0 -1.57 93920.0 -61300.0 -1.59 -2.2355 -1.0 3213658 CHDI2_000321 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O21 compound treatment 6080.0 -139000.0 -4.3 7360.0 -148000.0 -3.84 -5.76 -0.9984 3213618 CHDI2_000322 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(o1)c2cccc(Cl)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O22 compound treatment 64480.0 -80500.0 -2.49 90080.0 -65200.0 -1.69 -2.9607 -0.9822 3213662 CHDI2_000323 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O23 mock treatment 126160.0 -18800.0 -0.58 131720.0 -23500.0 -0.61 -0.8443 -0.9997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 O24 mock treatment 181160.0 36200.0 1.12 156160.0 914.0 0.02 0.8097 0.7219 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P01 compound treatment 91360.0 -53600.0 -1.66 68520.0 -86700.0 -2.25 -2.7679 -0.9887 3213584 CHDI2_000324 OCCOc1ccccc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P02 compound treatment 140800.0 -4170.0 -0.13 148920.0 -6330.0 -0.16 -0.2076 -0.9929 3213626 CHDI2_000325 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P03 compound treatment 96320.0 -48600.0 -1.51 126440.0 -28800.0 -0.75 -1.5951 -0.9478 3213588 CHDI2_000326 OCCOc1cccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P04 compound treatment 69000.0 -76000.0 -2.35 110840.0 -44400.0 -1.15 -2.4803 -0.9462 3213630 CHDI2_000327 Cn1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P05 compound treatment 100840.0 -44100.0 -1.37 144120.0 -11100.0 -0.29 -1.1712 -0.8381 3213592 CHDI2_000328 OCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P06 compound treatment 26480.0 -118000.0 -3.67 67960.0 -87300.0 -2.27 -4.1997 -0.9732 3213634 CHDI2_000329 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P07 compound treatment 107520.0 -37400.0 -1.16 150120.0 -5130.0 -0.13 -0.9146 -0.7831 3213596 CHDI2_000330 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P08 compound treatment 142320.0 -2650.0 -0.08 87560.0 -67700.0 -1.76 -1.3016 -0.7393 3213638 CHDI2_000331 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C2=CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P09 compound treatment 83200.0 -61800.0 -1.91 114400.0 -40800.0 -1.06 -2.1038 -0.9613 3213600 CHDI2_000332 COc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P10 compound treatment 126600.0 -18400.0 -0.57 118120.0 -37100.0 -0.96 -1.0845 -0.9683 3213642 CHDI2_000333 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P11 compound treatment 80640.0 -64300.0 -1.99 127240.0 -28000.0 -0.73 -1.9239 -0.9067 3214590 CHDI2_000334 ONC(=O)CCCCCC(=O)N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P12 compound treatment 82440.0 -62500.0 -1.94 116160.0 -39100.0 -1.02 -2.0881 -0.9546 3214716 CHDI2_000335 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P13 compound treatment 69040.0 -75900.0 -2.35 80280.0 -75000.0 -1.95 -3.0409 -0.9956 3213604 CHDI2_000336 COc1cc(/C=C/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P14 compound treatment 131120.0 -13800.0 -0.43 141120.0 -14100.0 -0.37 -0.5629 -0.997 3213644 CHDI2_000337 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P15 compound treatment 95880.0 -49100.0 -1.52 115960.0 -39300.0 -1.02 -1.7973 -0.9812 3213608 CHDI2_000338 Cc1ccc(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P16 compound treatment 133040.0 -11900.0 -0.37 127240.0 -28000.0 -0.73 -0.7759 -0.9507 3213648 CHDI2_000339 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P17 compound treatment 115480.0 -29500.0 -0.91 103200.0 -52000.0 -1.35 -1.6023 -0.9818 3213612 CHDI2_000340 OCc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P18 compound treatment 110600.0 -34400.0 -1.06 116920.0 -38300.0 -1.0 -1.4571 -0.9994 3213652 CHDI2_000341 C/C(=N\NC(=O)CCCCCCC(=O)Nc1ccccc1O)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P19 compound treatment 66320.0 -78600.0 -2.44 66960.0 -88300.0 -2.29 -3.3452 -0.9995 3213616 CHDI2_000342 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc3ccccc3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P20 compound treatment 57880.0 -87100.0 -2.7 70120.0 -85100.0 -2.21 -3.472 -0.9951 3213656 CHDI2_000343 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P21 compound treatment 30160.0 -115000.0 -3.56 40080.0 -115000.0 -2.99 -4.6313 -0.9963 3213620 CHDI2_000344 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P22 compound treatment 93840.0 -51100.0 -1.58 96120.0 -59100.0 -1.54 -2.2065 -0.9999 3213660 CHDI2_000345 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P23 mock treatment 142960.0 -2010.0 -0.06 145160.0 -10100.0 -0.26 -0.2293 -0.8513 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2403 P24 mock treatment 143560.0 -1410.0 -0.04 112920.0 -42300.0 -1.1 -0.8085 -0.7346 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A01 compound treatment 53320.0 -44500.0 -1.38 79720.0 -42700.0 -1.11 -1.7591 -0.9943 3214214 CHDI2_000346 NNC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A02 compound treatment 84720.0 -13100.0 -0.4 128800.0 6360.0 0.17 -0.1694 -0.3874 3214215 CHDI2_000347 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A03 compound treatment 18800.0 -79000.0 -2.45 22160.0 -100000.0 -2.61 -3.5729 -0.9995 3214216 CHDI2_000348 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A04 compound treatment 55400.0 -42400.0 -1.31 62400.0 -60000.0 -1.56 -2.0317 -0.9963 3214218 CHDI2_000349 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A05 compound treatment 17760.0 -80000.0 -2.48 29400.0 -93000.0 -2.42 -3.4627 -0.9999 3214220 CHDI2_000350 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A06 compound treatment 62560.0 -35200.0 -1.09 90120.0 -32300.0 -0.84 -1.3655 -0.9916 3214222 CHDI2_000351 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A07 compound treatment 28000.0 -69800.0 -2.16 39160.0 -83300.0 -2.16 -3.059 -1.0 3214224 CHDI2_000352 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A08 compound treatment 55560.0 -42200.0 -1.31 84320.0 -38100.0 -0.99 -1.6255 -0.9906 3214226 CHDI2_000353 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A09 compound treatment 30360.0 -67400.0 -2.09 37520.0 -84900.0 -2.21 -3.0374 -0.9996 3214228 CHDI2_000354 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2OCCOc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A10 compound treatment 46960.0 -50800.0 -1.57 69920.0 -52500.0 -1.36 -2.0784 -0.9975 3214230 CHDI2_000355 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3OCCOc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A11 compound treatment 57160.0 -40600.0 -1.26 79240.0 -43200.0 -1.12 -1.6837 -0.9984 3214232 CHDI2_000356 ONC(=O)CCCCCC(=O)N/N=C/COCc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A12 compound treatment 68800.0 -29000.0 -0.9 111440.0 -11000.0 -0.29 -0.8371 -0.8882 3214234 CHDI2_000357 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/COCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A13 compound treatment 21040.0 -76700.0 -2.38 32800.0 -89600.0 -2.33 -3.3283 -0.9999 3214720 CHDI2_000358 CCOc1cccc(/C=N/NC(=O)CCCCCC(=O)NO)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A14 compound treatment 16920.0 -80900.0 -2.51 22520.0 -99900.0 -2.6 -3.6075 -0.9998 3553354 CHDI2_000359 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A15 compound treatment 3480.0 -94300.0 -2.92 3960.0 -118000.0 -3.08 -4.2429 -0.9997 3214236 CHDI2_000360 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A16 compound treatment 36280.0 -61500.0 -1.91 46320.0 -76100.0 -1.98 -2.746 -0.9998 3214238 CHDI2_000361 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A17 compound treatment 7040.0 -90700.0 -2.81 8720.0 -114000.0 -2.95 -4.0775 -0.9997 3214240 CHDI2_000362 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A18 compound treatment 18640.0 -79100.0 -2.45 28000.0 -94400.0 -2.45 -3.4691 -1.0 3214242 CHDI2_000363 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A19 compound treatment 40480.0 -57300.0 -1.78 65080.0 -57400.0 -1.49 -2.3093 -0.9962 3214244 CHDI2_000364 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A20 compound treatment 59840.0 -37900.0 -1.18 96240.0 -26200.0 -0.68 -1.3127 -0.9662 3214246 CHDI2_000365 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A21 compound treatment 5600.0 -92200.0 -2.86 9560.0 -113000.0 -2.93 -4.0936 -0.9999 3214248 CHDI2_000366 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Br)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A22 compound treatment 48840.0 -48900.0 -1.52 64320.0 -58100.0 -1.51 -2.1401 -1.0 3214250 CHDI2_000367 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Br)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A23 mock treatment 124360.0 26600.0 0.82 134640.0 12200.0 0.32 0.8064 0.914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 A24 mock treatment 82360.0 -15400.0 -0.48 124760.0 2320.0 0.06 -0.2953 -0.613 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B01 compound treatment 18120.0 -79700.0 -2.47 16120.0 -106000.0 -2.76 -3.6988 -0.9984 3214256 CHDI2_000368 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B02 compound treatment 91880.0 -5910.0 -0.18 127760.0 5320.0 0.14 -0.0316 -0.1378 3214824 CHDI2_000369 NNC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B03 compound treatment 68520.0 -29300.0 -0.91 88560.0 -33900.0 -0.88 -1.2636 -0.9999 3214260 CHDI2_000370 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B04 compound treatment 44680.0 -53100.0 -1.65 57280.0 -65200.0 -1.69 -2.3606 -0.9999 3214826 CHDI2_000371 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B05 compound treatment 87240.0 -10500.0 -0.33 148640.0 26200.0 0.68 0.2504 0.3315 3214264 CHDI2_000372 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B06 compound treatment 75400.0 -22400.0 -0.69 114280.0 -8160.0 -0.21 -0.6403 -0.8829 3214830 CHDI2_000373 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B07 compound treatment 69160.0 -28600.0 -0.89 103600.0 -18800.0 -0.49 -0.9733 -0.9607 3214268 CHDI2_000374 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B08 compound treatment 72160.0 -25600.0 -0.79 91800.0 -30600.0 -0.8 -1.1243 -1.0 3214834 CHDI2_000375 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B09 compound treatment 84960.0 -12800.0 -0.4 111800.0 -10600.0 -0.28 -0.4764 -0.9843 3214272 CHDI2_000376 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B10 compound treatment 63000.0 -34800.0 -1.08 88640.0 -33800.0 -0.88 -1.3831 -0.9948 3214838 CHDI2_000377 ONC(=O)CCCCC(=O)N/N=C/c1ccc2OCCOc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B11 compound treatment 56720.0 -41100.0 -1.27 80960.0 -41500.0 -1.08 -1.6618 -0.9966 3214276 CHDI2_000378 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2c[nH]c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B12 compound treatment 96840.0 -945.0 -0.03 168120.0 45700.0 1.19 0.8186 0.6895 3214842 CHDI2_000379 ONC(=O)CCCCC(=O)N/N=C/COCc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B13 compound treatment 118720.0 20900.0 0.65 195280.0 72800.0 1.89 1.797 0.8982 3553415 CHDI2_000380 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B14 compound treatment 82040.0 -15700.0 -0.49 129240.0 6800.0 0.18 -0.22 -0.424 3553478 CHDI2_000381 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c(O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B15 compound treatment 41120.0 -56700.0 -1.76 57920.0 -64500.0 -1.68 -2.4269 -0.9997 3214280 CHDI2_000382 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(I)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B16 compound treatment 18040.0 -79700.0 -2.47 17600.0 -105000.0 -2.72 -3.6733 -0.9988 3214846 CHDI2_000383 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B17 compound treatment 84720.0 -13100.0 -0.4 125640.0 3200.0 0.08 -0.2274 -0.5503 3214284 CHDI2_000384 C/C=C(/C)\C=N\NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B18 compound treatment 7200.0 -90600.0 -2.81 9920.0 -113000.0 -2.92 -4.0519 -0.9998 3214850 CHDI2_000385 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B19 compound treatment 65520.0 -32300.0 -1.0 79720.0 -42700.0 -1.11 -1.4918 -0.9986 3214360 CHDI2_000386 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B20 compound treatment 69880.0 -27900.0 -0.86 105800.0 -16600.0 -0.43 -0.9171 -0.9487 3214854 CHDI2_000387 ONC(=O)CCCCC(=O)N/N=C/c1cccc(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B21 compound treatment 85560.0 -12200.0 -0.38 142080.0 19600.0 0.51 0.093 0.1464 3214292 CHDI2_000388 Cc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B22 compound treatment 63560.0 -34200.0 -1.06 114360.0 -8080.0 -0.21 -0.8983 -0.831 3214858 CHDI2_000389 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Br)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B23 mock treatment 97920.0 135.0 0.0 173880.0 51400.0 1.34 0.9481 0.7093 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 B24 mock treatment 98640.0 855.0 0.03 162240.0 39800.0 1.03 0.75 0.725 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C01 compound treatment 40440.0 -57300.0 -1.78 68080.0 -54400.0 -1.41 -2.2551 -0.9935 3214300 CHDI2_000390 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Br)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C02 compound treatment 71200.0 -26600.0 -0.82 112440.0 -10000.0 -0.26 -0.7662 -0.887 3214302 CHDI2_000391 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Br)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C03 compound treatment 19040.0 -78700.0 -2.44 21480.0 -101000.0 -2.62 -3.5801 -0.9993 3214304 CHDI2_000392 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C04 compound treatment 14520.0 -83300.0 -2.58 20320.0 -102000.0 -2.65 -3.7005 -0.9999 3214306 CHDI2_000393 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C05 compound treatment 6760.0 -91000.0 -2.82 16360.0 -106000.0 -2.76 -3.9432 -0.9999 3214308 CHDI2_000394 ONC(=O)CCCCCC(=O)N/N=C/c1cc(O)ccc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C06 compound treatment 15920.0 -81900.0 -2.54 22200.0 -100000.0 -2.6 -3.6353 -0.9999 3214310 CHDI2_000395 Oc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C07 compound treatment 8360.0 -89400.0 -2.77 11000.0 -111000.0 -2.9 -4.0067 -0.9998 3214312 CHDI2_000396 COc1cc(Br)cc(/C=N/NC(=O)CCCCCC(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C08 compound treatment 61360.0 -36400.0 -1.13 96120.0 -26300.0 -0.68 -1.2816 -0.9712 3214314 CHDI2_000397 COc1cc(Br)cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C09 compound treatment 6800.0 -91000.0 -2.82 8360.0 -114000.0 -2.96 -4.0893 -0.9997 3214316 CHDI2_000398 COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C10 compound treatment 21320.0 -76500.0 -2.37 27400.0 -95000.0 -2.47 -3.4214 -0.9998 3214318 CHDI2_000399 COc1ccc(Br)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C11 compound treatment 6440.0 -91300.0 -2.83 11640.0 -111000.0 -2.88 -4.037 -1.0 3214724 CHDI2_000400 ONC(=O)CCCCCC(=O)N/N=C/c1cc(I)cc(I)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C12 compound treatment 101120.0 3340.0 0.1 137360.0 14900.0 0.39 0.3472 0.8654 3553358 CHDI2_000401 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C13 compound treatment 9800.0 -88000.0 -2.73 14200.0 -108000.0 -2.81 -3.9163 -0.9999 3214320 CHDI2_000402 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C14 compound treatment 40760.0 -57000.0 -1.77 53320.0 -69100.0 -1.8 -2.5193 -1.0 3214322 CHDI2_000403 COc1ccc(Br)cc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C15 compound treatment 31160.0 -66600.0 -2.06 33840.0 -88600.0 -2.3 -3.0875 -0.9985 3214728 CHDI2_000404 CN(C)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C16 compound treatment 84320.0 -13500.0 -0.42 150200.0 27800.0 0.72 0.215 0.2581 3553362 CHDI2_000405 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C17 compound treatment 7400.0 -90400.0 -2.8 9880.0 -113000.0 -2.92 -4.0483 -0.9998 3214324 CHDI2_000406 ONC(=O)CCCCCC(=O)N/N=C/c1cc2OCOc2cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C18 compound treatment 29720.0 -68100.0 -2.11 31400.0 -91000.0 -2.37 -3.1639 -0.9984 3214326 CHDI2_000407 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C19 compound treatment 46440.0 -51300.0 -1.59 58520.0 -63900.0 -1.66 -2.2993 -0.9998 3214328 CHDI2_000408 ONC(=O)CCCCCC(=O)N/N=C/c1cccnc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C20 compound treatment 72080.0 -25700.0 -0.8 92200.0 -30200.0 -0.79 -1.1187 -1.0 3214330 CHDI2_000409 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccnc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C21 compound treatment 43760.0 -54000.0 -1.67 50840.0 -71600.0 -1.86 -2.4991 -0.9986 3214332 CHDI2_000410 ONC(=O)CCCCCC(=O)N/N=C/c1ccncc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C22 compound treatment 57360.0 -40400.0 -1.25 74080.0 -48400.0 -1.26 -1.7742 -1.0 3214334 CHDI2_000411 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccncc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C23 mock treatment 95080.0 -2710.0 -0.08 198000.0 75600.0 1.96 1.329 0.6763 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 C24 mock treatment 87680.0 -10100.0 -0.31 152360.0 29900.0 0.78 0.3283 0.3918 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D01 compound treatment 52760.0 -45000.0 -1.4 77600.0 -44800.0 -1.17 -1.8103 -0.996 3214340 CHDI2_000412 Cc1ccsc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D02 compound treatment 71280.0 -26500.0 -0.82 90080.0 -32400.0 -0.84 -1.1752 -0.9999 3214910 CHDI2_000413 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Br)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D03 compound treatment 91920.0 -5870.0 -0.18 93960.0 -28500.0 -0.74 -0.6517 -0.8553 3214344 CHDI2_000414 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCC(=O)Nc3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D04 compound treatment 37560.0 -60200.0 -1.87 48360.0 -74100.0 -1.92 -2.6805 -0.9999 3214914 CHDI2_000415 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D05 compound treatment 31800.0 -66000.0 -2.04 33280.0 -89200.0 -2.32 -3.0838 -0.9981 3214348 CHDI2_000416 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D06 compound treatment 34840.0 -62900.0 -1.95 37200.0 -85200.0 -2.21 -2.9451 -0.998 3214918 CHDI2_000417 ONC(=O)CCCCC(=O)N/N=C/c1cc(O)ccc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D07 compound treatment 22000.0 -75800.0 -2.35 38720.0 -83700.0 -2.18 -3.1985 -0.9993 3214356 CHDI2_000418 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3ccccc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D08 compound treatment 53320.0 -44500.0 -1.38 41000.0 -81400.0 -2.12 -2.4704 -0.9784 3214922 CHDI2_000419 COc1cc(Br)cc(/C=N/NC(=O)CCCCC(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D09 compound treatment 92200.0 -5590.0 -0.17 96840.0 -25600.0 -0.67 -0.5927 -0.8624 3214288 CHDI2_000420 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D10 compound treatment 8800.0 -89000.0 -2.76 9840.0 -113000.0 -2.93 -4.0183 -0.9996 3214926 CHDI2_000421 COc1ccc(Br)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D11 compound treatment 118320.0 20500.0 0.64 146840.0 24400.0 0.63 0.8982 1.0 3553419 CHDI2_000422 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D12 compound treatment 82960.0 -14800.0 -0.46 100080.0 -22400.0 -0.58 -0.7356 -0.9932 3553482 CHDI2_000423 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c(O)cc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D13 compound treatment 100080.0 2300.0 0.07 107840.0 -14600.0 -0.38 -0.2179 -0.5647 3214352 CHDI2_000424 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D14 compound treatment 18480.0 -79300.0 -2.46 18880.0 -104000.0 -2.69 -3.6402 -0.999 3214930 CHDI2_000425 COc1ccc(Br)cc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D15 compound treatment 115920.0 18100.0 0.56 139400.0 17000.0 0.44 0.7089 0.9928 3553423 CHDI2_000426 ONC(=O)c1cccc(c1)C(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D16 compound treatment 107160.0 9380.0 0.29 127680.0 5240.0 0.14 0.3017 0.9404 3553485 CHDI2_000427 COc1cc(OC)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D17 compound treatment 72560.0 -25200.0 -0.78 76120.0 -46300.0 -1.2 -1.4037 -0.9782 3214364 CHDI2_000428 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D18 compound treatment 13320.0 -84500.0 -2.62 13760.0 -109000.0 -2.82 -3.8473 -0.9993 3214934 CHDI2_000429 ONC(=O)CCCCC(=O)N/N=C/c1cc2OCOc2cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D19 compound treatment 115240.0 17500.0 0.54 129480.0 7040.0 0.18 0.5118 0.8964 3214368 CHDI2_000430 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D20 compound treatment 72560.0 -25200.0 -0.78 74240.0 -48200.0 -1.25 -1.4382 -0.9742 3214938 CHDI2_000431 ONC(=O)CCCCC(=O)N/N=C/c1cccnc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D21 compound treatment 71120.0 -26700.0 -0.83 58360.0 -64100.0 -1.66 -1.7615 -0.9477 3214372 CHDI2_000432 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D22 compound treatment 49760.0 -48000.0 -1.49 68600.0 -53800.0 -1.4 -2.0414 -0.9995 3214942 CHDI2_000433 ONC(=O)CCCCC(=O)N/N=C/c1ccncc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D23 mock treatment 127760.0 30000.0 0.93 128880.0 6440.0 0.17 0.7751 0.8213 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 D24 mock treatment 93640.0 -4150.0 -0.13 123800.0 1360.0 0.04 -0.0658 -0.494 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E01 compound treatment 6520.0 -91300.0 -2.83 8280.0 -114000.0 -2.97 -4.097 -0.9997 3214732 CHDI2_000434 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E02 compound treatment 114920.0 17100.0 0.53 126600.0 4160.0 0.11 0.4519 0.834 3553366 CHDI2_000435 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(O)ccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E03 compound treatment 16920.0 -80900.0 -2.51 14080.0 -108000.0 -2.82 -3.7625 -0.9983 3214380 CHDI2_000436 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(Br)s1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E04 compound treatment 53360.0 -44400.0 -1.38 57760.0 -64700.0 -1.68 -2.1616 -0.9951 3214382 CHDI2_000437 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Br)s2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E05 compound treatment 74880.0 -22900.0 -0.71 86320.0 -36100.0 -0.94 -1.1654 -0.9905 3214384 CHDI2_000438 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E06 compound treatment 47760.0 -50000.0 -1.55 58200.0 -64200.0 -1.67 -2.2762 -0.9993 3214386 CHDI2_000439 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E07 compound treatment 5920.0 -91900.0 -2.85 5800.0 -117000.0 -3.03 -4.1557 -0.9995 3214388 CHDI2_000440 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E08 compound treatment 27000.0 -70800.0 -2.19 20680.0 -102000.0 -2.64 -3.4204 -0.9957 3214390 CHDI2_000441 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E09 compound treatment 6240.0 -91500.0 -2.84 6880.0 -116000.0 -3.0 -4.1288 -0.9996 3214736 CHDI2_000442 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(c(F)c1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E10 compound treatment 101800.0 4020.0 0.12 120120.0 -2320.0 -0.06 0.0454 0.3282 3553369 CHDI2_000443 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E11 compound treatment 92400.0 -5390.0 -0.17 96240.0 -26200.0 -0.68 -0.5993 -0.8551 3214392 CHDI2_000444 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E12 compound treatment 112560.0 14800.0 0.46 129840.0 7400.0 0.19 0.4597 0.9258 3214394 CHDI2_000445 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E13 compound treatment 89520.0 -8270.0 -0.26 111280.0 -11200.0 -0.29 -0.3861 -0.9981 3214396 CHDI2_000446 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E14 compound treatment 96920.0 -865.0 -0.03 121360.0 -1080.0 -0.03 -0.0388 -0.9997 3214398 CHDI2_000447 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E15 compound treatment 33200.0 -64600.0 -2.0 38840.0 -83600.0 -2.17 -2.9509 -0.9992 3214400 CHDI2_000448 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E16 compound treatment 74240.0 -23500.0 -0.73 75680.0 -46800.0 -1.21 -1.3749 -0.9702 3214402 CHDI2_000449 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E17 compound treatment 95640.0 -2150.0 -0.07 120960.0 -1480.0 -0.04 -0.0742 -0.9661 3214784 CHDI2_000450 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(o1)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E18 compound treatment 93520.0 -4270.0 -0.13 124520.0 2080.0 0.05 -0.0552 -0.3866 3553372 CHDI2_000451 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2c[nH]c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E19 compound treatment 101040.0 3260.0 0.1 125920.0 3480.0 0.09 0.1353 0.9985 3214404 CHDI2_000452 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E20 compound treatment 121240.0 23500.0 0.73 137160.0 14700.0 0.38 0.7844 0.9551 3214406 CHDI2_000453 OC(=O)c1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E21 compound treatment 95960.0 -1830.0 -0.06 109480.0 -13000.0 -0.34 -0.2781 -0.8145 3214408 CHDI2_000454 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E22 compound treatment 102080.0 4300.0 0.13 129640.0 7200.0 0.19 0.2264 0.9861 3214410 CHDI2_000455 OC(=O)c1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E23 mock treatment 98160.0 375.0 0.01 114320.0 -8120.0 -0.21 -0.1409 -0.6671 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 E24 mock treatment 77160.0 -20600.0 -0.64 127920.0 5480.0 0.14 -0.3512 -0.5364 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F01 compound treatment 48680.0 -49100.0 -1.52 73400.0 -49000.0 -1.27 -1.9768 -0.9961 3553427 CHDI2_000456 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F02 compound treatment 110400.0 12600.0 0.39 116080.0 -6360.0 -0.17 0.1596 0.376 3553487 CHDI2_000457 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F03 compound treatment 27760.0 -70000.0 -2.17 31480.0 -91000.0 -2.36 -3.2054 -0.9991 3214416 CHDI2_000458 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F04 compound treatment 57040.0 -40700.0 -1.26 60520.0 -61900.0 -1.61 -2.0303 -0.9928 3214990 CHDI2_000459 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Br)s1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F05 compound treatment 101600.0 3820.0 0.12 116000.0 -6440.0 -0.17 -0.0347 -0.1695 3214420 CHDI2_000460 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F06 compound treatment 88960.0 -8830.0 -0.27 87320.0 -35100.0 -0.91 -0.8386 -0.8803 3214994 CHDI2_000461 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F07 compound treatment 96480.0 -1310.0 -0.04 105800.0 -16600.0 -0.43 -0.3343 -0.7699 3214424 CHDI2_000462 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F08 compound treatment 14920.0 -82900.0 -2.57 10960.0 -111000.0 -2.9 -3.8637 -0.9982 3214998 CHDI2_000463 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccccc2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F09 compound treatment 70800.0 -27000.0 -0.84 71360.0 -51100.0 -1.33 -1.5297 -0.9752 3553430 CHDI2_000464 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F10 compound treatment 115800.0 18000.0 0.56 129160.0 6720.0 0.17 0.5182 0.886 3553491 CHDI2_000465 CC(C)(C)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F11 compound treatment 118360.0 20600.0 0.64 135520.0 13100.0 0.34 0.6911 0.9566 3214428 CHDI2_000466 Cc1ncc(CO)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F12 compound treatment 127120.0 29300.0 0.91 130320.0 7880.0 0.2 0.7875 0.8452 3215002 CHDI2_000467 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F13 compound treatment 114160.0 16400.0 0.51 124120.0 1680.0 0.04 0.3897 0.7652 3214432 CHDI2_000468 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F14 compound treatment 111840.0 14100.0 0.44 135600.0 13200.0 0.34 0.5497 0.9928 3215006 CHDI2_000469 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F15 compound treatment 90840.0 -6950.0 -0.22 116040.0 -6400.0 -0.17 -0.2697 -0.9919 3214436 CHDI2_000470 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F16 compound treatment 84680.0 -13100.0 -0.41 91880.0 -30600.0 -0.79 -0.8486 -0.9515 3215010 CHDI2_000471 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F17 compound treatment 21280.0 -76500.0 -2.37 22960.0 -99500.0 -2.58 -3.5039 -0.9991 3553434 CHDI2_000472 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F18 compound treatment 107200.0 9420.0 0.29 145240.0 22800.0 0.59 0.6252 0.9467 3553494 CHDI2_000473 CC1=C(C/C=N/NC(=O)c2cccc(c2)C(=O)NO)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F19 compound treatment 101000.0 3220.0 0.1 107680.0 -14800.0 -0.38 -0.2007 -0.5066 3214440 CHDI2_000474 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F20 compound treatment 118160.0 20400.0 0.63 118720.0 -3720.0 -0.1 0.3781 0.592 3215014 CHDI2_000475 ONC(=O)CCCCC(=O)N/N=C/c1cccc(c1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F21 compound treatment 108400.0 10600.0 0.33 116440.0 -6000.0 -0.16 0.1224 0.3362 3214444 CHDI2_000476 CCCCCCC/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F22 compound treatment 105760.0 7980.0 0.25 155720.0 33300.0 0.86 0.7862 0.8742 3215018 CHDI2_000477 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F23 mock treatment 111680.0 13900.0 0.43 144880.0 22400.0 0.58 0.7167 0.9889 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 F24 mock treatment 79080.0 -18700.0 -0.58 126480.0 4040.0 0.11 -0.3356 -0.5697 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G01 compound treatment 20880.0 -76900.0 -2.38 17640.0 -105000.0 -2.72 -3.6104 -0.9978 3214452 CHDI2_000478 ONC(=O)CCCCCC(=O)N/N=C/c1ccccc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G02 compound treatment 61960.0 -35800.0 -1.11 72480.0 -50000.0 -1.3 -1.7028 -0.997 3214454 CHDI2_000479 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccccc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G03 compound treatment 42640.0 -55100.0 -1.71 49520.0 -72900.0 -1.89 -2.5479 -0.9987 3214788 CHDI2_000480 Cn1cc(/C=N/NC(=O)CCCCCC(=O)NO)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G04 compound treatment 68160.0 -29600.0 -0.92 74400.0 -48000.0 -1.25 -1.5317 -0.9886 3553376 CHDI2_000481 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(I)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G05 compound treatment 64640.0 -33100.0 -1.03 69480.0 -53000.0 -1.38 -1.6992 -0.9896 3214456 CHDI2_000482 ONC(=O)CCCCCC(=O)N/N=C/c1cccnc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G06 compound treatment 82400.0 -15400.0 -0.48 91000.0 -31400.0 -0.82 -0.9147 -0.9671 3214458 CHDI2_000483 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccnc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G07 compound treatment 20440.0 -77300.0 -2.4 19240.0 -103000.0 -2.68 -3.5906 -0.9984 3214460 CHDI2_000484 ONC(=O)CCCCCC(=O)N/N=C/C=C/c1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G08 compound treatment 81840.0 -15900.0 -0.49 90400.0 -32000.0 -0.83 -0.938 -0.969 3214462 CHDI2_000485 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G09 compound treatment 88160.0 -9630.0 -0.3 93800.0 -28600.0 -0.74 -0.737 -0.9194 3214464 CHDI2_000486 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G10 compound treatment 102960.0 5180.0 0.16 111200.0 -11200.0 -0.29 -0.0931 -0.2795 3214466 CHDI2_000487 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G11 compound treatment 99320.0 1540.0 0.05 105320.0 -17100.0 -0.44 -0.2809 -0.6279 3214468 CHDI2_000488 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G12 compound treatment 117400.0 19600.0 0.61 122640.0 201.0 0.01 0.4334 0.7132 3214469 CHDI2_000489 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G13 compound treatment 48120.0 -49700.0 -1.54 59520.0 -62900.0 -1.63 -2.2441 -0.9995 3214470 CHDI2_000490 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(C#N)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G14 compound treatment 88000.0 -9790.0 -0.3 106200.0 -16200.0 -0.42 -0.5127 -0.9869 3214472 CHDI2_000491 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(C#N)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G15 compound treatment 102800.0 5020.0 0.16 109640.0 -12800.0 -0.33 -0.1253 -0.3413 3214474 CHDI2_000492 ONC(=O)CCCCCC(=O)N/N=C/C1CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G16 compound treatment 109640.0 11900.0 0.37 125600.0 3160.0 0.08 0.3178 0.8444 3214476 CHDI2_000493 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G17 compound treatment 23040.0 -74700.0 -2.32 30360.0 -92100.0 -2.39 -3.3293 -0.9999 3214478 CHDI2_000494 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G18 compound treatment 70680.0 -27100.0 -0.84 79160.0 -43300.0 -1.12 -1.389 -0.9897 3214480 CHDI2_000495 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G19 compound treatment 12440.0 -85300.0 -2.64 14880.0 -108000.0 -2.79 -3.846 -0.9996 3214792 CHDI2_000496 ONC(=O)CCCCCC(=O)N/N=C/c1cn(Cc2ccccc2)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G20 compound treatment 128040.0 30300.0 0.94 119200.0 -3240.0 -0.08 0.6034 0.6411 3553380 CHDI2_000497 C/C=C(/C)\C=N\NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G21 compound treatment 9880.0 -87900.0 -2.72 10040.0 -112000.0 -2.92 -3.991 -0.9994 3214482 CHDI2_000498 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)cc(Br)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G22 compound treatment 11560.0 -86200.0 -2.67 11160.0 -111000.0 -2.89 -3.9336 -0.9992 3214484 CHDI2_000499 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G23 mock treatment 104600.0 6820.0 0.21 123320.0 881.0 0.02 0.1655 0.7792 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 G24 mock treatment 85520.0 -12300.0 -0.38 123080.0 641.0 0.02 -0.2569 -0.6755 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H01 compound treatment 76360.0 -21400.0 -0.66 101120.0 -21300.0 -0.55 -0.8611 -0.996 3214490 CHDI2_000500 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H02 compound treatment 54160.0 -43600.0 -1.35 64600.0 -57800.0 -1.5 -2.0184 -0.9986 3215062 CHDI2_000501 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H03 compound treatment 126200.0 28400.0 0.88 140960.0 18500.0 0.48 0.9628 0.9596 3553438 CHDI2_000502 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H04 compound treatment 141680.0 43900.0 1.36 130880.0 8440.0 0.22 1.1168 0.8107 3553498 CHDI2_000503 NC(=O)COc1ccccc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H05 compound treatment 67160.0 -30600.0 -0.95 83680.0 -38800.0 -1.01 -1.3831 -0.9996 3214494 CHDI2_000504 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H06 compound treatment 99040.0 1260.0 0.04 100200.0 -22200.0 -0.58 -0.3811 -0.658 3215066 CHDI2_000505 ONC(=O)CCCCC(=O)N/N=C/c1cccnc1Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H07 compound treatment 144040.0 46300.0 1.43 151840.0 29400.0 0.76 1.5536 0.9566 3214498 CHDI2_000506 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H08 compound treatment 103600.0 5820.0 0.18 100200.0 -22200.0 -0.58 -0.2812 -0.4646 3215070 CHDI2_000507 ONC(=O)CCCCC(=O)N/N=C/C=C/c1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H09 compound treatment 114200.0 16400.0 0.51 135880.0 13400.0 0.35 0.6066 0.9832 3214502 CHDI2_000508 Oc1cc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H10 compound treatment 126680.0 28900.0 0.9 137960.0 15500.0 0.4 0.9182 0.9351 3215074 CHDI2_000509 C[C@H](CCC=C(C)C)C/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H11 compound treatment 130160.0 32400.0 1.0 149240.0 26800.0 0.7 1.2017 0.9841 3214506 CHDI2_000510 COc1cc(OC)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H12 compound treatment 130240.0 32500.0 1.01 131960.0 9520.0 0.25 0.886 0.8556 3215078 CHDI2_000511 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H13 compound treatment 130800.0 33000.0 1.02 122160.0 -279.0 -0.01 0.7182 0.7021 3214510 CHDI2_000512 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H14 compound treatment 102440.0 4660.0 0.14 113720.0 -8720.0 -0.23 -0.0582 -0.2167 3215080 CHDI2_000513 ONC(=O)CCCCC(=O)N/N=C/c1ccc(C#N)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H15 compound treatment 132640.0 34900.0 1.08 126080.0 3640.0 0.09 0.8305 0.7661 3214514 CHDI2_000514 CC(C)(C)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H16 compound treatment 133320.0 35500.0 1.1 129680.0 7240.0 0.19 0.9116 0.8161 3215084 CHDI2_000515 ONC(=O)CCCCC(=O)N/N=C/C1CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H17 compound treatment 89600.0 -8190.0 -0.25 102040.0 -20400.0 -0.53 -0.5541 -0.9431 3214518 CHDI2_000516 CC1=C(C/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H18 compound treatment 67080.0 -30700.0 -0.95 76160.0 -46300.0 -1.2 -1.523 -0.9933 3215088 CHDI2_000517 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H19 compound treatment 137160.0 39400.0 1.22 122240.0 -199.0 -0.01 0.859 0.7041 3553442 CHDI2_000518 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H20 compound treatment 132120.0 34300.0 1.06 134440.0 12000.0 0.31 0.9728 0.8775 3553502 CHDI2_000519 NC(=O)COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H21 compound treatment 111840.0 14100.0 0.44 121720.0 -719.0 -0.02 0.2947 0.6762 3214522 CHDI2_000520 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H22 compound treatment 10880.0 -86900.0 -2.69 11600.0 -111000.0 -2.88 -3.9404 -0.9994 3215092 CHDI2_000521 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)cc(Br)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H23 mock treatment 116520.0 18700.0 0.58 128040.0 5600.0 0.15 0.5134 0.8578 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 H24 mock treatment 90160.0 -7630.0 -0.24 118560.0 -3880.0 -0.1 -0.2383 -0.9278 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I01 compound treatment 15040.0 -82700.0 -2.56 19480.0 -103000.0 -2.68 -3.7045 -0.9998 3214530 CHDI2_000522 COc1cc(Cl)c(/C=N/NC(=O)CCCCCC(=O)NO)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I02 compound treatment 96520.0 -1270.0 -0.04 102760.0 -19700.0 -0.51 -0.3893 -0.7591 3214532 CHDI2_000523 COc1cc(Cl)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I03 compound treatment 54600.0 -43200.0 -1.34 40360.0 -82100.0 -2.13 -2.4542 -0.9748 3214534 CHDI2_000524 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Cl)cc(Cl)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I04 compound treatment 12560.0 -85200.0 -2.64 13720.0 -109000.0 -2.82 -3.8647 -0.9994 3214536 CHDI2_000525 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I05 compound treatment 74800.0 -23000.0 -0.71 69200.0 -53200.0 -1.38 -1.4817 -0.9523 3214796 CHDI2_000526 ONC(=O)CCCCCC(=O)N/N=C/C1=CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I06 compound treatment 100320.0 2540.0 0.08 108720.0 -13700.0 -0.36 -0.1965 -0.5384 3553384 CHDI2_000527 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I07 compound treatment 88960.0 -8830.0 -0.27 97840.0 -24600.0 -0.64 -0.6453 -0.9282 3214538 CHDI2_000528 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)cc([N+](=O)[O-])c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I08 compound treatment 105120.0 7340.0 0.23 101400.0 -21000.0 -0.55 -0.2258 -0.3815 3214540 CHDI2_000529 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I09 compound treatment 10560.0 -87200.0 -2.7 11600.0 -111000.0 -2.88 -3.9474 -0.9995 3214542 CHDI2_000530 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I10 compound treatment 36800.0 -61000.0 -1.89 42760.0 -79700.0 -2.07 -2.8 -0.999 3214544 CHDI2_000531 CCN(CC)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I11 compound treatment 49360.0 -48400.0 -1.5 65120.0 -57300.0 -1.49 -2.1141 -1.0 3214546 CHDI2_000532 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2OCCc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I12 compound treatment 100360.0 2580.0 0.08 112280.0 -10200.0 -0.26 -0.1302 -0.4723 3214548 CHDI2_000533 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3OCCc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I13 compound treatment 77960.0 -19800.0 -0.61 84800.0 -37600.0 -0.98 -1.1259 -0.9749 3214550 CHDI2_000534 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I14 compound treatment 53280.0 -44500.0 -1.38 61440.0 -61000.0 -1.58 -2.0958 -0.9976 3214552 CHDI2_000535 Oc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I15 compound treatment 89480.0 -8310.0 -0.26 97600.0 -24800.0 -0.65 -0.6383 -0.9187 3214554 CHDI2_000536 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I16 compound treatment 65120.0 -32700.0 -1.01 69040.0 -53400.0 -1.39 -1.6967 -0.988 3214556 CHDI2_000537 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I17 compound treatment 103040.0 5260.0 0.16 109120.0 -13300.0 -0.35 -0.1296 -0.3388 3214558 CHDI2_000538 ONC(=O)CCCCCC(=O)N/N=C/c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I18 compound treatment 86840.0 -10900.0 -0.34 100880.0 -21600.0 -0.56 -0.6359 -0.9711 3214560 CHDI2_000539 Oc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I19 compound treatment 99520.0 1740.0 0.05 106480.0 -16000.0 -0.41 -0.2552 -0.6103 3214562 CHDI2_000540 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I20 compound treatment 100480.0 2700.0 0.08 91040.0 -31400.0 -0.82 -0.5178 -0.6314 3214564 CHDI2_000541 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I21 compound treatment 111760.0 14000.0 0.43 118720.0 -3720.0 -0.1 0.2379 0.5361 3214799 CHDI2_000542 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I22 compound treatment 117960.0 20200.0 0.63 124800.0 2360.0 0.06 0.4854 0.7728 3553388 CHDI2_000543 Cc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I23 mock treatment 115520.0 17700.0 0.55 130520.0 8080.0 0.21 0.537 0.9129 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 I24 mock treatment 82280.0 -15500.0 -0.48 101920.0 -20500.0 -0.53 -0.7167 -0.9986 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J01 compound treatment 135760.0 38000.0 1.18 160120.0 37700.0 0.98 1.5243 0.9958 3214570 CHDI2_000544 Oc1ccccc1NC(=O)CCCCCC(=O)NN=C2CCCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J02 compound treatment 76920.0 -20900.0 -0.65 71800.0 -50600.0 -1.32 -1.3875 -0.9465 3215140 CHDI2_000545 COc1cc(Cl)c(/C=N/NC(=O)CCCCC(=O)NO)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J03 compound treatment 114080.0 16300.0 0.5 118160.0 -4280.0 -0.11 0.2784 0.5385 3214572 CHDI2_000546 Oc1ccccc1NC(=O)CCCCCC(=O)NN=C2CCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J04 compound treatment 60120.0 -37700.0 -1.17 69640.0 -52800.0 -1.37 -1.7953 -0.9968 3215144 CHDI2_000547 ONC(=O)CCCCC(=O)N/N=C/c1cc(Cl)cc(Cl)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J05 compound treatment 124720.0 26900.0 0.83 118800.0 -3640.0 -0.09 0.5233 0.623 3553446 CHDI2_000548 Cc1ncc(CO)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J06 compound treatment 118680.0 20900.0 0.65 129640.0 7200.0 0.19 0.5901 0.8756 3554234 CHDI2_000549 ONC(=O)c1cccc(c1)C(=O)NN=C2CCCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J07 compound treatment 119600.0 21800.0 0.68 120560.0 -1880.0 -0.05 0.4434 0.6543 3214574 CHDI2_000550 Oc1ccccc1NC(=O)CCCCCC(=O)NN=C2CCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J08 compound treatment 99640.0 1860.0 0.06 91880.0 -30600.0 -0.79 -0.5208 -0.6542 3215148 CHDI2_000551 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)cc([N+](=O)[O-])c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J09 compound treatment 111240.0 13500.0 0.42 100800.0 -21600.0 -0.56 -0.1028 -0.1468 3214215 CHDI2_000552 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J10 compound treatment 25400.0 -72400.0 -2.24 27640.0 -94800.0 -2.46 -3.3276 -0.9989 3215152 CHDI2_000553 CCN(CC)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J11 compound treatment 62200.0 -35600.0 -1.1 71000.0 -51400.0 -1.34 -1.7247 -0.9954 3214576 CHDI2_000554 COc1cc(Br)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J12 compound treatment 98400.0 615.0 0.02 97520.0 -24900.0 -0.65 -0.4443 -0.686 3215156 CHDI2_000555 ONC(=O)CCCCC(=O)N/N=C/c1ccc2OCCc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J13 compound treatment 74880.0 -22900.0 -0.71 81680.0 -40800.0 -1.06 -1.2507 -0.981 3214580 CHDI2_000556 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/CCC2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J14 compound treatment 66440.0 -31300.0 -0.97 78560.0 -43900.0 -1.14 -1.4929 -0.9968 3215160 CHDI2_000557 ONC(=O)CCCCC(=O)N/N=C/c1cccc(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J15 compound treatment 20720.0 -77100.0 -2.39 28160.0 -94300.0 -2.45 -3.4206 -0.9999 3214584 CHDI2_000558 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J16 compound treatment 103040.0 5260.0 0.16 102840.0 -19600.0 -0.51 -0.2449 -0.4582 3215164 CHDI2_000559 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J17 compound treatment 105120.0 7340.0 0.23 106680.0 -15800.0 -0.41 -0.1288 -0.2751 3214588 CHDI2_000560 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J18 compound treatment 105400.0 7620.0 0.24 120120.0 -2320.0 -0.06 0.1242 0.5102 3215168 CHDI2_000561 ONC(=O)CCCCC(=O)N/N=C/c1cc(O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J19 compound treatment 118320.0 20500.0 0.64 114760.0 -7680.0 -0.2 0.3088 0.4631 3214215 CHDI2_000562 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J20 compound treatment 107280.0 9500.0 0.29 101320.0 -21100.0 -0.55 -0.18 -0.2891 3215172 CHDI2_000563 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J21 compound treatment 132200.0 34400.0 1.07 151560.0 29100.0 0.76 1.289 0.9859 3553450 CHDI2_000564 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J22 compound treatment 115040.0 17300.0 0.53 117480.0 -4960.0 -0.13 0.2869 0.5218 3554232 CHDI2_000565 ONC(=O)c1cccc(c1)C(=O)NN=C2CCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J23 mock treatment 112440.0 14700.0 0.45 121360.0 -1080.0 -0.03 0.3013 0.6622 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 J24 mock treatment 78600.0 -19200.0 -0.59 104320.0 -18100.0 -0.47 -0.7532 -0.9933 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K01 compound treatment 85480.0 -12300.0 -0.38 121160.0 -1280.0 -0.03 -0.2931 -0.7658 3214592 CHDI2_000566 COc1cccc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K02 compound treatment 102480.0 4700.0 0.15 107560.0 -14900.0 -0.39 -0.1705 -0.4128 3214594 CHDI2_000567 COc1cccc(OC)c1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K03 compound treatment 91080.0 -6710.0 -0.21 104280.0 -18200.0 -0.47 -0.4805 -0.9321 3214596 CHDI2_000568 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K04 compound treatment 97880.0 95.0 0.0 116280.0 -6160.0 -0.16 -0.1111 -0.694 3214598 CHDI2_000569 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K05 compound treatment 111240.0 13500.0 0.42 108960.0 -13500.0 -0.35 0.0472 0.0866 3214600 CHDI2_000570 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K06 compound treatment 105200.0 7420.0 0.23 112040.0 -10400.0 -0.27 -0.0286 -0.0806 3214602 CHDI2_000571 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K07 compound treatment 104400.0 6620.0 0.2 109920.0 -12500.0 -0.33 -0.0851 -0.2213 3214802 CHDI2_000572 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K08 compound treatment 113080.0 15300.0 0.47 111480.0 -11000.0 -0.28 0.1338 0.2419 3553391 CHDI2_000573 Cc1[nH]cnc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K09 compound treatment 108160.0 10400.0 0.32 121520.0 -919.0 -0.02 0.2104 0.6528 3214604 CHDI2_000574 CC1(C)COC(CCC/C=N/NC(=O)CCCCCC(=O)NO)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K10 compound treatment 108640.0 10900.0 0.34 108680.0 -13800.0 -0.36 -0.015 -0.0305 3214606 CHDI2_000575 CC1(C)COC(CCC/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K11 compound treatment 110520.0 12700.0 0.39 107760.0 -14700.0 -0.38 0.0093 0.017 3214608 CHDI2_000576 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K12 compound treatment 120920.0 23100.0 0.72 102400.0 -20000.0 -0.52 0.1387 0.1566 3214610 CHDI2_000577 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCCC(=O)Nc3ccccc3O)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K13 compound treatment 13040.0 -84700.0 -2.63 14400.0 -108000.0 -2.81 -3.8417 -0.9994 3214612 CHDI2_000578 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)cs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K14 compound treatment 61080.0 -36700.0 -1.14 77040.0 -45400.0 -1.18 -1.6383 -0.9998 3214614 CHDI2_000579 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)cs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K15 compound treatment 112600.0 14800.0 0.46 112360.0 -10100.0 -0.26 0.1394 0.2638 3214806 CHDI2_000580 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K16 compound treatment 122960.0 25200.0 0.78 111560.0 -10900.0 -0.28 0.3517 0.4239 3553395 CHDI2_000581 Cc1ccsc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K17 compound treatment 108560.0 10800.0 0.33 111840.0 -10600.0 -0.28 0.0413 0.0955 3214616 CHDI2_000582 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K18 compound treatment 111880.0 14100.0 0.44 114160.0 -8280.0 -0.22 0.1567 0.3219 3214618 CHDI2_000583 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K19 compound treatment 8280.0 -89500.0 -2.77 8760.0 -114000.0 -2.95 -4.0496 -0.9995 3214620 CHDI2_000584 ONC(=O)CCCCCC(=O)N/N=C/c1ccc-2c(Cc3ccccc32)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K20 compound treatment 15840.0 -81900.0 -2.54 19440.0 -103000.0 -2.68 -3.6877 -0.9997 3214622 CHDI2_000585 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K21 compound treatment 53320.0 -44500.0 -1.38 59920.0 -62500.0 -1.62 -2.1228 -0.9966 3214624 CHDI2_000586 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(F)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K22 compound treatment 80680.0 -17100.0 -0.53 90920.0 -31500.0 -0.82 -0.9538 -0.9778 3214626 CHDI2_000587 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(F)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K23 mock treatment 102160.0 4380.0 0.14 119520.0 -2920.0 -0.08 0.0422 0.2719 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 K24 mock treatment 103160.0 5380.0 0.17 122200.0 -239.0 -0.01 0.1134 0.6803 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L01 compound treatment 108760.0 11000.0 0.34 164720.0 42300.0 1.1 1.0173 0.8846 3214628 CHDI2_000588 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L02 compound treatment 100040.0 2260.0 0.07 105400.0 -17000.0 -0.44 -0.2636 -0.5882 3215202 CHDI2_000589 COc1cccc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L03 compound treatment 128480.0 30700.0 0.95 122280.0 -159.0 0.0 0.6696 0.704 3214632 CHDI2_000590 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L04 compound treatment 103960.0 6180.0 0.19 105960.0 -16500.0 -0.43 -0.1675 -0.3571 3215206 CHDI2_000591 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L05 compound treatment 116800.0 19000.0 0.59 107440.0 -15000.0 -0.39 0.141 0.1997 3214636 CHDI2_000592 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L06 compound treatment 125080.0 27300.0 0.85 129320.0 6880.0 0.18 0.7244 0.8381 3215210 CHDI2_000593 COc1cc(O)cc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L07 compound treatment 87640.0 -10100.0 -0.31 98040.0 -24400.0 -0.63 -0.6705 -0.9476 3553454 CHDI2_000594 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L08 compound treatment 113240.0 15500.0 0.48 105760.0 -16700.0 -0.43 0.0322 0.0498 3553643 CHDI2_000595 ONC(=O)c1cccc(c1)C(=O)N/N=C/Cc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L09 compound treatment 101840.0 4060.0 0.13 104480.0 -18000.0 -0.47 -0.2411 -0.4989 3214640 CHDI2_000596 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L10 compound treatment 109400.0 11600.0 0.36 96600.0 -25800.0 -0.67 -0.2202 -0.2891 3215214 CHDI2_000597 CC1(C)COC(CCC/C=N/NC(=O)CCCCC(=O)NO)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L11 compound treatment 104480.0 6700.0 0.21 96160.0 -26300.0 -0.68 -0.3361 -0.471 3214642 CHDI2_000598 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L12 compound treatment 111480.0 13700.0 0.42 102440.0 -20000.0 -0.52 -0.0674 -0.1004 3215218 CHDI2_000599 Cc1nnc(Sc2ccc(/C=N/NC(=O)CCCCC(=O)NO)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L13 compound treatment 111480.0 13700.0 0.42 100760.0 -21700.0 -0.56 -0.0982 -0.1393 3214644 CHDI2_000600 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L14 compound treatment 81160.0 -16600.0 -0.52 83880.0 -38600.0 -1.0 -1.0727 -0.9522 3215222 CHDI2_000601 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)cs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L15 compound treatment 61920.0 -35900.0 -1.11 68080.0 -54400.0 -1.41 -1.7845 -0.993 3553458 CHDI2_000602 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L16 compound treatment 102960.0 5180.0 0.16 108400.0 -14000.0 -0.36 -0.1445 -0.3628 3553647 CHDI2_000603 COC(=O)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L17 compound treatment 28840.0 -68900.0 -2.14 33800.0 -88600.0 -2.3 -3.1391 -0.9993 3214648 CHDI2_000604 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L18 compound treatment 104840.0 7060.0 0.22 106600.0 -15800.0 -0.41 -0.1364 -0.2928 3215226 CHDI2_000605 CC(C)(C)OC(=O)NC/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L19 compound treatment 107840.0 10100.0 0.31 110400.0 -12000.0 -0.31 -9.0E-4 -0.002 3214652 CHDI2_000606 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L20 compound treatment 10920.0 -86900.0 -2.69 14040.0 -108000.0 -2.82 -3.8947 -0.9997 3215230 CHDI2_000607 ONC(=O)CCCCC(=O)N/N=C/c1ccc-2c(Cc3ccccc32)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L21 compound treatment 75520.0 -22300.0 -0.69 82880.0 -39600.0 -1.03 -1.2146 -0.9812 3214656 CHDI2_000608 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3ccccc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L22 compound treatment 100080.0 2300.0 0.07 96480.0 -26000.0 -0.67 -0.4266 -0.6291 3215234 CHDI2_000609 ONC(=O)CCCCC(=O)N/N=C/c1ccc(F)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L23 mock treatment 104560.0 6780.0 0.21 112000.0 -10400.0 -0.27 -0.0434 -0.1264 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 L24 mock treatment 99080.0 1300.0 0.04 106320.0 -16100.0 -0.42 -0.2678 -0.6364 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M01 compound treatment 73560.0 -24200.0 -0.75 112520.0 -9920.0 -0.26 -0.713 -0.8984 3214660 CHDI2_000610 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M02 compound treatment 95720.0 -2070.0 -0.06 101400.0 -21000.0 -0.55 -0.4318 -0.7845 3214662 CHDI2_000611 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M03 compound treatment 14200.0 -83600.0 -2.59 14120.0 -108000.0 -2.81 -3.8214 -0.9991 3214664 CHDI2_000612 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(F)c(Oc2ccccc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M04 compound treatment 14800.0 -83000.0 -2.57 19480.0 -103000.0 -2.68 -3.7098 -0.9998 3214666 CHDI2_000613 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M05 compound treatment 58000.0 -39800.0 -1.23 65160.0 -57300.0 -1.49 -1.924 -0.9956 3214668 CHDI2_000614 ONC(=O)CCCCCC(=O)N/N=C/c1cc(F)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M06 compound treatment 93960.0 -3830.0 -0.12 101040.0 -21400.0 -0.56 -0.477 -0.839 3214670 CHDI2_000615 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(F)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M07 compound treatment 107920.0 10100.0 0.31 110240.0 -12200.0 -0.32 -0.0021 -0.0046 3214672 CHDI2_000616 ONC(=O)CCCCCC(=O)N/N=C/c1coc2ccccc2c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M08 compound treatment 114080.0 16300.0 0.5 117600.0 -4840.0 -0.13 0.2681 0.5153 3214674 CHDI2_000617 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M09 compound treatment 65640.0 -32100.0 -1.0 69800.0 -52600.0 -1.37 -1.6714 -0.9879 3214814 CHDI2_000618 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M10 compound treatment 110600.0 12800.0 0.4 130800.0 8360.0 0.22 0.4344 0.9597 3553403 CHDI2_000619 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M11 compound treatment 33440.0 -64300.0 -1.99 44040.0 -78400.0 -2.04 -2.8501 -0.9999 3214676 CHDI2_000620 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M12 compound treatment 62760.0 -35000.0 -1.09 64960.0 -57500.0 -1.49 -1.8234 -0.9877 3214678 CHDI2_000621 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M13 compound treatment 95840.0 -1950.0 -0.06 99000.0 -23400.0 -0.61 -0.4732 -0.7733 3214818 CHDI2_000622 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M14 compound treatment 117960.0 20200.0 0.63 131560.0 9120.0 0.24 0.6096 0.9119 3553407 CHDI2_000623 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3ccccc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M15 compound treatment 117600.0 19800.0 0.61 107640.0 -14800.0 -0.38 0.1622 0.224 3214680 CHDI2_000624 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(c1)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M16 compound treatment 102960.0 5180.0 0.16 112840.0 -9600.0 -0.25 -0.063 -0.2124 3214682 CHDI2_000625 OB(O)c1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M17 compound treatment 83400.0 -14400.0 -0.45 86360.0 -36100.0 -0.94 -0.978 -0.9422 3214684 CHDI2_000626 ONC(=O)CCCCCC(=O)N/N=C/c1ccco1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M18 compound treatment 105960.0 8180.0 0.25 114680.0 -7760.0 -0.2 0.0366 0.1129 3214686 CHDI2_000627 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccco2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M19 compound treatment 92960.0 -4830.0 -0.15 89160.0 -33300.0 -0.86 -0.7171 -0.8172 3214688 CHDI2_000628 ONC(=O)CCCCCC(=O)N/N=C/c1ccoc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M20 compound treatment 114960.0 17200.0 0.53 114080.0 -8360.0 -0.22 0.2227 0.3875 3214690 CHDI2_000629 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccoc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M21 compound treatment 80080.0 -17700.0 -0.55 102120.0 -20300.0 -0.53 -0.7612 -0.9998 3214692 CHDI2_000630 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M22 compound treatment 76600.0 -21200.0 -0.66 86480.0 -36000.0 -0.93 -1.1248 -0.9851 3214694 CHDI2_000631 Oc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M23 mock treatment 114600.0 16800.0 0.52 107240.0 -15200.0 -0.39 0.0892 0.1364 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 M24 mock treatment 93040.0 -4750.0 -0.15 111720.0 -10700.0 -0.28 -0.3009 -0.9554 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N01 compound treatment 70880.0 -26900.0 -0.83 111000.0 -11400.0 -0.3 -0.7996 -0.9035 3214700 CHDI2_000632 Cc1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N02 compound treatment 117120.0 19300.0 0.6 128040.0 5600.0 0.15 0.5265 0.854 3215270 CHDI2_000633 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c(F)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N03 compound treatment 100440.0 2660.0 0.08 122240.0 -199.0 -0.01 0.0545 0.6614 3214704 CHDI2_000634 COc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N04 compound treatment 51520.0 -46300.0 -1.43 50960.0 -71500.0 -1.86 -2.3269 -0.9918 3215274 CHDI2_000635 ONC(=O)CCCCC(=O)N/N=C/c1ccc(F)c(Oc2ccccc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N05 compound treatment 110360.0 12600.0 0.39 123720.0 1280.0 0.03 0.2991 0.7647 3214708 CHDI2_000636 O[C@@H](/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N06 compound treatment 78800.0 -19000.0 -0.59 93480.0 -29000.0 -0.75 -0.948 -0.9926 3215278 CHDI2_000637 ONC(=O)CCCCC(=O)N/N=C/c1cc(F)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N07 compound treatment 120520.0 22700.0 0.7 98960.0 -23500.0 -0.61 0.0667 0.0716 3214712 CHDI2_000638 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N08 compound treatment 107000.0 9220.0 0.29 112480.0 -9960.0 -0.26 0.0189 0.0491 3215282 CHDI2_000639 ONC(=O)CCCCC(=O)N/N=C/c1coc2ccccc2c1=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N09 compound treatment 122040.0 24300.0 0.75 120880.0 -1560.0 -0.04 0.5028 0.668 3553466 CHDI2_000640 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2nccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N10 compound treatment 110200.0 12400.0 0.38 119960.0 -2480.0 -0.06 0.2265 0.5806 3553651 CHDI2_000641 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc3ccccc3n2S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N11 compound treatment 97120.0 -665.0 -0.02 96920.0 -25500.0 -0.66 -0.4834 -0.7287 3214714 CHDI2_000642 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N12 compound treatment 58360.0 -39400.0 -1.22 66320.0 -56100.0 -1.46 -1.8948 -0.9961 3215286 CHDI2_000643 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N13 compound treatment 106920.0 9140.0 0.28 125720.0 3280.0 0.09 0.2604 0.881 3553471 CHDI2_000644 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N14 compound treatment 9360.0 -88400.0 -2.74 10840.0 -112000.0 -2.9 -3.9877 -0.9996 3553510 CHDI2_000645 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N15 compound treatment 94800.0 -2990.0 -0.09 106400.0 -16000.0 -0.42 -0.3601 -0.8435 3214718 CHDI2_000646 CCOc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N16 compound treatment 113160.0 15400.0 0.48 101560.0 -20900.0 -0.54 -0.0467 -0.0647 3215290 CHDI2_000647 ONC(=O)CCCCC(=O)N/N=C/c1cccc(c1)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N17 compound treatment 15880.0 -81900.0 -2.54 20680.0 -102000.0 -2.64 -3.6641 -0.9998 3214722 CHDI2_000648 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N18 compound treatment 108840.0 11100.0 0.34 106200.0 -16200.0 -0.42 -0.0561 -0.1033 3215294 CHDI2_000649 ONC(=O)CCCCC(=O)N/N=C/c1ccco1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N19 compound treatment 104880.0 7100.0 0.22 103480.0 -19000.0 -0.49 -0.1929 -0.3576 3214726 CHDI2_000650 CN(C)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N20 compound treatment 100200.0 2420.0 0.07 107720.0 -14700.0 -0.38 -0.2175 -0.5582 3215298 CHDI2_000651 ONC(=O)CCCCC(=O)N/N=C/c1ccoc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N21 compound treatment 58000.0 -39800.0 -1.23 74160.0 -48300.0 -1.25 -1.7587 -1.0 3214730 CHDI2_000652 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCCC(=O)Nc4ccccc4O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N22 compound treatment 92240.0 -5550.0 -0.17 94720.0 -27700.0 -0.72 -0.6308 -0.8519 3215302 CHDI2_000653 ONC(=O)CCCCC(=O)N/N=C/c1cccc(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N23 mock treatment 101760.0 3980.0 0.12 116600.0 -5840.0 -0.15 -0.0202 -0.1033 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 N24 mock treatment 106720.0 8940.0 0.28 134960.0 12500.0 0.33 0.4258 0.9968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O01 compound treatment 65880.0 -31900.0 -0.99 99600.0 -22800.0 -0.59 -1.1186 -0.9702 3214738 CHDI2_000654 OCCOc1ccccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O02 compound treatment 72360.0 -25400.0 -0.79 98680.0 -23800.0 -0.62 -0.9936 -0.9927 3214740 CHDI2_000655 OCCOc1ccccc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O03 compound treatment 81880.0 -15900.0 -0.49 95200.0 -27200.0 -0.71 -0.8489 -0.9843 3214742 CHDI2_000656 OCCOc1cccc(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O04 compound treatment 94920.0 -2870.0 -0.09 98920.0 -23500.0 -0.61 -0.4949 -0.8014 3214744 CHDI2_000657 OCCOc1cccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O05 compound treatment 80400.0 -17400.0 -0.54 88160.0 -34300.0 -0.89 -1.0107 -0.971 3214746 CHDI2_000658 OCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O06 compound treatment 107440.0 9660.0 0.3 101920.0 -20500.0 -0.53 -0.1654 -0.2706 3214748 CHDI2_000659 OCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O07 compound treatment 50120.0 -47700.0 -1.48 49680.0 -72800.0 -1.89 -2.3811 -0.9925 3214750 CHDI2_000660 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O08 compound treatment 82880.0 -14900.0 -0.46 84240.0 -38200.0 -0.99 -1.0284 -0.9394 3214752 CHDI2_000661 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O09 compound treatment 65360.0 -32400.0 -1.0 74360.0 -48100.0 -1.25 -1.5937 -0.9942 3214754 CHDI2_000662 COc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O10 compound treatment 85400.0 -12400.0 -0.38 84640.0 -37800.0 -0.98 -0.9658 -0.916 3214756 CHDI2_000663 COc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O11 compound treatment 86440.0 -11300.0 -0.35 82720.0 -39700.0 -1.03 -0.9783 -0.8973 3214822 CHDI2_000664 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O12 compound treatment 113280.0 15500.0 0.48 126320.0 3880.0 0.1 0.4108 0.8374 3553411 CHDI2_000665 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O13 compound treatment 77240.0 -20500.0 -0.64 92600.0 -29800.0 -0.78 -0.9983 -0.9952 3214758 CHDI2_000666 COc1cc(/C=C/C=N/NC(=O)CCCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O14 compound treatment 85480.0 -12300.0 -0.38 101240.0 -21200.0 -0.55 -0.6591 -0.9839 3214760 CHDI2_000667 COc1cc(/C=C/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O15 compound treatment 24800.0 -73000.0 -2.26 29360.0 -93100.0 -2.42 -3.3092 -0.9994 3214762 CHDI2_000668 Cc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O16 compound treatment 84840.0 -12900.0 -0.4 85600.0 -36800.0 -0.96 -0.9604 -0.9254 3214764 CHDI2_000669 Cc1ccc(O)c(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O17 compound treatment 102440.0 4660.0 0.14 110800.0 -11600.0 -0.3 -0.1118 -0.3338 3214766 CHDI2_000670 OCc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O18 compound treatment 123240.0 25500.0 0.79 135280.0 12800.0 0.33 0.7936 0.9267 3214768 CHDI2_000671 OCc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O19 compound treatment 7520.0 -90300.0 -2.8 12720.0 -110000.0 -2.85 -3.9935 -1.0 3214770 CHDI2_000672 ONC(=O)CCCCCC(=O)N/N=C/c1ccc2ccccc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O20 compound treatment 13640.0 -84100.0 -2.61 15800.0 -107000.0 -2.77 -3.8028 -0.9995 3214772 CHDI2_000673 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc3ccccc3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O21 compound treatment 7920.0 -89900.0 -2.78 9280.0 -113000.0 -2.94 -4.0479 -0.9996 3214774 CHDI2_000674 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(o1)c2cccc(Cl)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O22 compound treatment 10280.0 -87500.0 -2.71 14760.0 -108000.0 -2.8 -3.8955 -0.9999 3214776 CHDI2_000675 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O23 mock treatment 95120.0 -2670.0 -0.08 95400.0 -27000.0 -0.7 -0.5552 -0.7848 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 O24 mock treatment 107760.0 9980.0 0.31 129120.0 6680.0 0.17 0.3413 0.9628 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P01 compound treatment 55080.0 -42700.0 -1.32 69800.0 -52600.0 -1.37 -1.9027 -0.9999 3214782 CHDI2_000676 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P02 compound treatment 45520.0 -52300.0 -1.62 67680.0 -54800.0 -1.42 -2.1512 -0.9979 3215348 CHDI2_000677 OCCOc1ccccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P03 compound treatment 67720.0 -30100.0 -0.93 86280.0 -36200.0 -0.94 -1.323 -1.0 3214786 CHDI2_000678 Cn1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P04 compound treatment 85120.0 -12700.0 -0.39 105200.0 -17200.0 -0.45 -0.5942 -0.9978 3215352 CHDI2_000679 OCCOc1cccc(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P05 compound treatment 16960.0 -80800.0 -2.5 21960.0 -100000.0 -2.61 -3.6169 -0.9998 3214790 CHDI2_000680 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P06 compound treatment 102120.0 4340.0 0.13 103280.0 -19200.0 -0.5 -0.257 -0.4985 3215356 CHDI2_000681 OCCOc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P07 compound treatment 109320.0 11500.0 0.36 111520.0 -10900.0 -0.28 0.0521 0.1142 3214794 CHDI2_000682 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C2=CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P08 compound treatment 69800.0 -28000.0 -0.87 76680.0 -45800.0 -1.19 -1.4538 -0.988 3215360 CHDI2_000683 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P09 compound treatment 113760.0 16000.0 0.49 114880.0 -7560.0 -0.2 0.2111 0.3965 3214798 CHDI2_000684 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P10 compound treatment 63560.0 -34200.0 -1.06 66840.0 -55600.0 -1.44 -1.7713 -0.9884 3215364 CHDI2_000685 COc1ccc(O)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P11 compound treatment 111800.0 14000.0 0.43 117360.0 -5080.0 -0.13 0.2138 0.471 3553474 CHDI2_000686 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P12 compound treatment 116680.0 18900.0 0.59 118520.0 -3920.0 -0.1 0.342 0.5755 3553514 CHDI2_000687 ONC(=O)c1cccc(c1)C(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P13 compound treatment 104920.0 7140.0 0.22 104760.0 -17700.0 -0.46 -0.1685 -0.3305 3214800 CHDI2_000688 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P14 compound treatment 104680.0 6900.0 0.21 104920.0 -17500.0 -0.46 -0.1708 -0.3397 3215368 CHDI2_000689 COc1cc(/C=C/C=N/NC(=O)CCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P15 compound treatment 100400.0 2620.0 0.08 111440.0 -11000.0 -0.29 -0.1448 -0.4874 3214804 CHDI2_000690 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P16 compound treatment 51920.0 -45900.0 -1.42 58120.0 -64300.0 -1.67 -2.1866 -0.9967 3215372 CHDI2_000691 Cc1ccc(O)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P17 compound treatment 101440.0 3660.0 0.11 104040.0 -18400.0 -0.48 -0.258 -0.5251 3214808 CHDI2_000692 C/C(=N\NC(=O)CCCCCC(=O)Nc1ccccc1O)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P18 compound treatment 101560.0 3780.0 0.12 107200.0 -15200.0 -0.4 -0.1973 -0.4778 3215376 CHDI2_000693 OCc1ccc(/C=N/NC(=O)CCCCC(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P19 compound treatment 54840.0 -42900.0 -1.33 58400.0 -64000.0 -1.66 -2.1175 -0.9939 3214812 CHDI2_000694 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P20 compound treatment 15200.0 -82600.0 -2.56 23560.0 -98900.0 -2.57 -3.626 -1.0 3215380 CHDI2_000695 ONC(=O)CCCCC(=O)N/N=C/c1ccc2ccccc2c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P21 compound treatment 63480.0 -34300.0 -1.06 71160.0 -51300.0 -1.33 -1.6937 -0.9937 3214816 CHDI2_000696 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P22 compound treatment 6400.0 -91400.0 -2.83 7640.0 -115000.0 -2.98 -4.1113 -0.9997 3215384 CHDI2_000697 ONC(=O)CCCCC(=O)N/N=C/c1ccc(o1)c2cccc(Cl)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P23 mock treatment 82960.0 -14800.0 -0.46 99760.0 -22700.0 -0.59 -0.7415 -0.9924 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2404 P24 mock treatment 59040.0 -38700.0 -1.2 75480.0 -47000.0 -1.22 -1.7116 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A01 compound treatment 14120.0 -99900.0 -3.1 8320.0 -121000.0 -3.15 -4.4202 -1.0 3214868 CHDI2_000698 ONC(=O)CCCCC(=O)N/N=C/c1c(O)ccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A02 compound treatment 162720.0 48700.0 1.51 147680.0 17900.0 0.47 1.396 0.8844 3551921 CHDI2_000699 NNC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A03 compound treatment 102000.0 -12000.0 -0.37 74600.0 -55100.0 -1.43 -1.277 -0.8625 3214872 CHDI2_000700 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A04 compound treatment 203200.0 89200.0 2.76 162280.0 32500.0 0.85 2.5511 0.8831 3552997 CHDI2_000701 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A05 compound treatment 160280.0 46200.0 1.43 111120.0 -18600.0 -0.48 0.6708 0.4436 3214876 CHDI2_000702 ONC(=O)CCCCC(=O)N/N=C/c1ccc([N+](=O)[O-])c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A06 compound treatment 190840.0 76800.0 2.38 111280.0 -18500.0 -0.48 1.3433 0.5534 3553001 CHDI2_000703 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A07 compound treatment 179280.0 65200.0 2.02 75400.0 -54300.0 -1.41 0.4308 0.1747 3214880 CHDI2_000704 ONC(=O)CCCCC(=O)N/N=C/c1cc(O)ccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A08 compound treatment 178120.0 64100.0 1.99 119240.0 -10500.0 -0.27 1.2109 0.6042 3553005 CHDI2_000705 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A09 compound treatment 153960.0 39900.0 1.24 81320.0 -48400.0 -1.26 -0.0151 -0.0086 3214884 CHDI2_000706 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)n2ccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A10 compound treatment 207840.0 93800.0 2.91 77840.0 -51900.0 -1.35 1.1014 0.3438 3553009 CHDI2_000707 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3OCCOc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A11 compound treatment 140120.0 26100.0 0.81 65000.0 -64700.0 -1.68 -0.6182 -0.3313 3214888 CHDI2_000708 ONC(=O)CCCCC(=O)N/N=C/c1c[nH]c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A12 compound treatment 176640.0 62600.0 1.94 144760.0 15000.0 0.39 1.6473 0.8327 3553013 CHDI2_000709 ONC(=O)c1cccc(c1)C(=O)N/N=C/COCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A13 compound treatment 197760.0 83700.0 2.59 125160.0 -4580.0 -0.12 1.7499 0.6739 3553655 CHDI2_000710 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A14 compound treatment 207280.0 93200.0 2.89 106680.0 -23100.0 -0.6 1.619 0.5488 3553589 CHDI2_000711 CCOc1cccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A15 compound treatment 98120.0 -15900.0 -0.49 56960.0 -72800.0 -1.89 -1.6861 -0.8627 3214892 CHDI2_000712 ONC(=O)CCCCC(=O)N/N=C/c1ccc(I)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A16 compound treatment 158640.0 44600.0 1.38 71200.0 -58500.0 -1.52 -0.0985 -0.048 3553017 CHDI2_000713 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A17 compound treatment 154440.0 40400.0 1.25 110680.0 -19100.0 -0.5 0.5348 0.3973 3214896 CHDI2_000714 C/C=C(/C)\C=N\NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A18 compound treatment 212000.0 98000.0 3.04 95800.0 -33900.0 -0.88 1.5225 0.4817 3553021 CHDI2_000715 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A19 compound treatment 120960.0 6910.0 0.21 46200.0 -83500.0 -2.17 -1.3834 -0.6342 3214972 CHDI2_000716 ONC(=O)CCCCC(=O)N/N=C/c1ccc(s1)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A20 compound treatment 206800.0 92800.0 2.87 147200.0 17500.0 0.45 2.3529 0.8087 3553025 CHDI2_000717 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A21 compound treatment 117880.0 3830.0 0.12 90160.0 -39600.0 -1.03 -0.6432 -0.6213 3214904 CHDI2_000718 Cc1ccc(/C=N/NC(=O)CCCCC(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A22 compound treatment 113080.0 -966.0 -0.03 110520.0 -19200.0 -0.5 -0.3743 -0.7481 3553029 CHDI2_000719 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Br)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A23 mock treatment 156640.0 42600.0 1.32 164200.0 34500.0 0.9 1.5663 0.9821 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 A24 mock treatment 88560.0 -25500.0 -0.79 107640.0 -22100.0 -0.57 -0.9645 -0.9878 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B01 compound treatment 134600.0 20600.0 0.64 100520.0 -29200.0 -0.76 -0.0866 -0.0873 3551923 CHDI2_000720 NNC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B02 compound treatment 35880.0 -78200.0 -2.42 24360.0 -105000.0 -2.74 -3.6487 -0.9981 3553956 CHDI2_000721 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c(O)ccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B03 compound treatment 190760.0 76700.0 2.38 124600.0 -5140.0 -0.13 1.5863 0.6663 3553662 CHDI2_000722 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B04 compound treatment 203760.0 89700.0 2.78 129800.0 57.5 0.0 1.9666 0.7075 3553960 CHDI2_000723 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B05 compound treatment 137080.0 23000.0 0.71 85440.0 -44300.0 -1.15 -0.3093 -0.2284 3553666 CHDI2_000724 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B06 compound treatment 190840.0 76800.0 2.38 154360.0 24600.0 0.64 2.1348 0.8664 3553964 CHDI2_000725 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B07 compound treatment 174880.0 60800.0 1.88 93880.0 -35900.0 -0.93 0.674 0.3205 3553670 CHDI2_000726 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B08 compound treatment 156240.0 42200.0 1.31 103680.0 -26100.0 -0.68 0.4456 0.3027 3553968 CHDI2_000727 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(O)ccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B09 compound treatment 159960.0 45900.0 1.42 78480.0 -51300.0 -1.33 0.0641 0.0329 3553675 CHDI2_000728 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3OCCOc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B10 compound treatment 151560.0 37500.0 1.16 89240.0 -40500.0 -1.05 0.0778 0.0496 3553971 CHDI2_000729 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B11 compound treatment 183760.0 69700.0 2.16 107600.0 -22100.0 -0.58 1.1206 0.5013 3553679 CHDI2_000730 ONC(=O)c1ccc(cc1)C(=O)N/N=C/COCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B12 compound treatment 182800.0 68800.0 2.13 150040.0 20300.0 0.53 1.8793 0.8563 3553975 CHDI2_000731 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c[nH]c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B13 compound treatment 39080.0 -75000.0 -2.32 30000.0 -99700.0 -2.59 -3.475 -0.9985 3552713 CHDI2_000732 Oc1ccc2ccccc2c1/C=N/NC(=O)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B14 compound treatment 167480.0 53400.0 1.66 160080.0 30300.0 0.79 1.7281 0.9424 3552763 CHDI2_000733 COc1cc(/C=N/NC(=O)c2ccccn2)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B15 compound treatment 142400.0 28400.0 0.88 78880.0 -50900.0 -1.32 -0.3132 -0.1974 3553682 CHDI2_000734 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B16 compound treatment 157960.0 43900.0 1.36 76160.0 -53600.0 -1.39 -0.0223 -0.0115 3553978 CHDI2_000735 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(I)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B17 compound treatment 167120.0 53100.0 1.64 94520.0 -35200.0 -0.92 0.5157 0.274 3553686 CHDI2_000736 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B18 compound treatment 203280.0 89200.0 2.76 126600.0 -3140.0 -0.08 1.8973 0.6859 3553981 CHDI2_000737 C/C=C(/C)\C=N\NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B19 compound treatment 203480.0 89400.0 2.77 116520.0 -13200.0 -0.34 1.7165 0.6147 3553690 CHDI2_000738 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B20 compound treatment 128040.0 14000.0 0.43 75680.0 -54100.0 -1.4 -0.6867 -0.4671 3553985 CHDI2_000739 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B21 compound treatment 137040.0 23000.0 0.71 89560.0 -40200.0 -1.04 -0.2345 -0.1855 3553695 CHDI2_000740 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Br)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B22 compound treatment 220520.0 106000.0 3.3 144720.0 15000.0 0.39 2.608 0.7851 3553989 CHDI2_000741 Cc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B23 mock treatment 198720.0 84700.0 2.62 175880.0 46100.0 1.2 2.7028 0.937 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 B24 mock treatment 134000.0 20000.0 0.62 155960.0 26200.0 0.68 0.9189 0.9988 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C01 compound treatment 59560.0 -54500.0 -1.69 44960.0 -84800.0 -2.2 -2.7514 -0.9914 3214952 CHDI2_000742 Cc1ccsc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C02 compound treatment 223960.0 110000.0 3.41 132840.0 3100.0 0.08 2.4651 0.7236 3553037 CHDI2_000743 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Br)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C03 compound treatment 148680.0 34600.0 1.07 90560.0 -39200.0 -1.02 0.0389 0.0263 3214956 CHDI2_000744 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C04 compound treatment 162240.0 48200.0 1.49 106480.0 -23300.0 -0.6 0.6285 0.3901 3553041 CHDI2_000745 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C05 compound treatment 17400.0 -96600.0 -2.99 11880.0 -118000.0 -3.06 -4.2829 -0.9999 3214960 CHDI2_000746 ONC(=O)CCCCC(=O)N/N=C/c1cccc2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C06 compound treatment 154000.0 40000.0 1.24 114080.0 -15700.0 -0.41 0.5876 0.4509 3553045 CHDI2_000747 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(O)ccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C07 compound treatment 89280.0 -24800.0 -0.77 34440.0 -95300.0 -2.48 -2.2936 -0.8847 3214968 CHDI2_000748 ONC(=O)CCCCC(=O)N/N=C/c1ccc2ccccc2c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C08 compound treatment 68200.0 -45800.0 -1.42 60200.0 -69500.0 -1.81 -2.2821 -0.9929 3553049 CHDI2_000749 COc1cc(Br)cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C09 compound treatment 108040.0 -6010.0 -0.19 56200.0 -73500.0 -1.91 -1.4827 -0.7723 3214900 CHDI2_000750 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C10 compound treatment 186280.0 72200.0 2.24 135640.0 5900.0 0.15 1.691 0.7538 3553053 CHDI2_000751 COc1ccc(Br)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C11 compound treatment 165760.0 51700.0 1.6 130240.0 498.0 0.01 1.1422 0.7128 3553658 CHDI2_000752 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCC#C)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C12 compound treatment 18560.0 -95500.0 -2.96 15680.0 -114000.0 -2.96 -4.1877 -1.0 3553593 CHDI2_000753 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C13 compound treatment 124680.0 10600.0 0.33 113800.0 -15900.0 -0.41 -0.0599 -0.1132 3214964 CHDI2_000754 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C14 compound treatment 185000.0 71000.0 2.2 156320.0 26600.0 0.69 2.0429 0.8865 3553057 CHDI2_000755 COc1ccc(Br)cc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C15 compound treatment 182240.0 68200.0 2.11 181840.0 52100.0 1.35 2.4513 0.9768 3553517 CHDI2_000756 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C16 compound treatment 190000.0 76000.0 2.35 106400.0 -23300.0 -0.61 1.2352 0.5083 3553597 CHDI2_000757 CN(C)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C17 compound treatment 180320.0 66300.0 2.05 94840.0 -34900.0 -0.91 0.8108 0.3612 3214976 CHDI2_000758 ONC(=O)CCCCC(=O)N/N=C/c1c(F)c(F)c(F)c(F)c1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C18 compound treatment 193440.0 79400.0 2.46 97360.0 -32400.0 -0.84 1.1445 0.4402 3553061 CHDI2_000759 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C19 compound treatment 183800.0 69800.0 2.16 135960.0 6220.0 0.16 1.6425 0.7578 3214980 CHDI2_000760 ONC(=O)CCCCC(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C20 compound treatment 190240.0 76200.0 2.36 181040.0 51300.0 1.33 2.6118 0.9634 3553065 CHDI2_000761 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccnc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C21 compound treatment 139240.0 25200.0 0.78 100760.0 -29000.0 -0.75 0.0195 0.018 3214984 CHDI2_000762 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C22 compound treatment 208240.0 94200.0 2.92 159800.0 30100.0 0.78 2.616 0.8659 3553069 CHDI2_000763 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccncc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C23 mock treatment 194640.0 80600.0 2.5 162360.0 32600.0 0.85 2.365 0.8968 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 C24 mock treatment 153320.0 39300.0 1.22 146520.0 16800.0 0.44 1.1687 0.9041 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D01 compound treatment 124800.0 10800.0 0.33 87480.0 -42300.0 -1.1 -0.5408 -0.4713 3553703 CHDI2_000764 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Br)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D02 compound treatment 123360.0 9310.0 0.29 99480.0 -30300.0 -0.79 -0.3519 -0.4202 3553995 CHDI2_000765 Cc1ccsc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D03 compound treatment 135400.0 21400.0 0.66 110040.0 -19700.0 -0.51 0.1059 0.1266 3553706 CHDI2_000766 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D04 compound treatment 142160.0 28100.0 0.87 117720.0 -12000.0 -0.31 0.3951 0.4269 3553998 CHDI2_000767 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3ccc(cc3)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D05 compound treatment 149600.0 35600.0 1.1 115800.0 -13900.0 -0.36 0.5228 0.4508 3553710 CHDI2_000768 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(O)ccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D06 compound treatment 94120.0 -19900.0 -0.62 90440.0 -39300.0 -1.02 -1.1586 -0.971 3554002 CHDI2_000769 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D07 compound treatment 96080.0 -18000.0 -0.56 54400.0 -75300.0 -1.96 -1.7779 -0.8735 3553714 CHDI2_000770 COc1cc(Br)cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D08 compound treatment 133720.0 19700.0 0.61 86600.0 -43100.0 -1.12 -0.3616 -0.2834 3554006 CHDI2_000771 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3ccccc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D09 compound treatment 115800.0 1750.0 0.05 83960.0 -45800.0 -1.19 -0.8027 -0.6741 3553718 CHDI2_000772 COc1ccc(Br)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D10 compound treatment 100480.0 -13600.0 -0.42 116920.0 -12800.0 -0.33 -0.5328 -0.9934 3554009 CHDI2_000773 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D11 compound treatment 145320.0 31300.0 0.97 97400.0 -32300.0 -0.84 0.091 0.0709 3552716 CHDI2_000774 Oc1ccc(/C=N/NC(=O)c2ccccn2)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D12 compound treatment 112880.0 -1170.0 -0.04 100320.0 -29400.0 -0.76 -0.5661 -0.7397 3552765 CHDI2_000775 Fc1c(F)c(F)c(/C=N/NC(=O)c2ccccn2)c(F)c1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D13 compound treatment 140200.0 26200.0 0.81 115120.0 -14600.0 -0.38 0.3044 0.3401 3553722 CHDI2_000776 COc1ccc(Br)cc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D14 compound treatment 140360.0 26300.0 0.82 117480.0 -12300.0 -0.32 0.3512 0.4012 3554013 CHDI2_000777 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D15 compound treatment 119320.0 5270.0 0.16 124480.0 -5260.0 -0.14 0.0189 0.0886 3552720 CHDI2_000778 Oc1cc(/C=N/NC(=O)c2ccccn2)ccc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D16 compound treatment 109960.0 -4090.0 -0.13 128720.0 -1020.0 -0.03 -0.1083 -0.8373 3552767 CHDI2_000779 C=CCC/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D17 compound treatment 126000.0 12000.0 0.37 81000.0 -48700.0 -1.27 -0.6336 -0.4802 3553726 CHDI2_000780 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D18 compound treatment 125880.0 11800.0 0.37 102000.0 -27700.0 -0.72 -0.2504 -0.3096 3554017 CHDI2_000781 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D19 compound treatment 136400.0 22400.0 0.69 109480.0 -20300.0 -0.53 0.1175 0.1351 3553730 CHDI2_000782 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccnc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D20 compound treatment 129960.0 15900.0 0.49 118360.0 -11400.0 -0.3 0.1395 0.2427 3554021 CHDI2_000783 ONC(=O)c1ccc(cc1)C(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D21 compound treatment 136520.0 22500.0 0.7 121600.0 -8140.0 -0.21 0.3428 0.471 3553734 CHDI2_000784 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccncc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D22 compound treatment 55760.0 -58300.0 -1.81 53120.0 -76600.0 -1.99 -2.6848 -0.9988 3554025 CHDI2_000785 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D23 mock treatment 153600.0 39600.0 1.23 150440.0 20700.0 0.54 1.2469 0.9316 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 D24 mock treatment 129560.0 15500.0 0.48 118960.0 -10800.0 -0.28 0.1418 0.2549 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E01 compound treatment 138280.0 24200.0 0.75 122200.0 -7540.0 -0.2 0.3924 0.5056 3553522 CHDI2_000786 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E02 compound treatment 14760.0 -99300.0 -3.08 9280.0 -120000.0 -3.13 -4.3885 -1.0 3553601 CHDI2_000787 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4cccc(c4)C(=O)NO)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E03 compound treatment 28840.0 -85200.0 -2.64 13360.0 -116000.0 -3.02 -4.005 -0.9977 3215028 CHDI2_000788 ONC(=O)CCCCC(=O)N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E04 compound treatment 124960.0 10900.0 0.34 85400.0 -44300.0 -1.15 -0.5756 -0.4793 3553077 CHDI2_000789 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Br)s2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E05 compound treatment 129720.0 15700.0 0.49 99120.0 -30600.0 -0.8 -0.2192 -0.2351 3215032 CHDI2_000790 ONC(=O)CCCCC(=O)N/N=C/c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E06 compound treatment 134240.0 20200.0 0.63 115880.0 -13900.0 -0.36 0.1878 0.2601 3553081 CHDI2_000791 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E07 compound treatment 131360.0 17300.0 0.54 97760.0 -32000.0 -0.83 -0.2083 -0.2105 3215036 CHDI2_000792 ONC(=O)CCCCC(=O)N/N=C/c1cccnc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E08 compound treatment 25240.0 -88800.0 -2.75 15680.0 -114000.0 -2.96 -4.0413 -0.9993 3553084 CHDI2_000793 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E09 compound treatment 134840.0 20800.0 0.64 109640.0 -20100.0 -0.52 0.0863 0.104 3553525 CHDI2_000794 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E10 compound treatment 35480.0 -78600.0 -2.43 26120.0 -104000.0 -2.69 -3.6251 -0.9987 3553605 CHDI2_000795 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E11 compound treatment 103360.0 -10700.0 -0.33 92480.0 -37300.0 -0.97 -0.9187 -0.8979 3215040 CHDI2_000796 Cc1ncc(CO)c(/C=N/NC(=O)CCCCC(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E12 compound treatment 144920.0 30900.0 0.96 162160.0 32400.0 0.84 1.272 0.998 3553088 CHDI2_000797 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E13 compound treatment 142720.0 28700.0 0.89 124280.0 -5460.0 -0.14 0.5279 0.5867 3215044 CHDI2_000798 ONC(=O)CCCCC(=O)N/N=C/c1ccc[nH]1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E14 compound treatment 119720.0 5670.0 0.18 140760.0 11000.0 0.29 0.3267 0.9726 3553092 CHDI2_000799 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E15 compound treatment 113600.0 -446.0 -0.01 87800.0 -41900.0 -1.09 -0.7804 -0.716 3215048 CHDI2_000800 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)N2CCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E16 compound treatment 123760.0 9710.0 0.3 106000.0 -23700.0 -0.62 -0.2234 -0.3254 3553096 CHDI2_000801 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E17 compound treatment 151440.0 37400.0 1.16 146640.0 16900.0 0.44 1.1297 0.9118 3553530 CHDI2_000802 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E18 compound treatment 166680.0 52600.0 1.63 139280.0 9540.0 0.25 1.3284 0.8053 3553608 CHDI2_000803 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E19 compound treatment 115960.0 1910.0 0.06 103840.0 -25900.0 -0.67 -0.434 -0.6423 3215052 CHDI2_000804 ONC(=O)CCCCC(=O)N/N=C/c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E20 compound treatment 144040.0 30000.0 0.93 160000.0 30300.0 0.79 1.2131 0.9965 3553100 CHDI2_000805 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(c2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E21 compound treatment 144720.0 30700.0 0.95 150280.0 20500.0 0.53 1.0494 0.9627 3215056 CHDI2_000806 CCCCCCC/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E22 compound treatment 205320.0 91300.0 2.83 133280.0 3540.0 0.09 2.0648 0.7297 3553104 CHDI2_000807 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E23 mock treatment 166240.0 52200.0 1.62 175040.0 45300.0 1.18 1.9758 0.9878 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 E24 mock treatment 136880.0 22800.0 0.71 121000.0 -8740.0 -0.23 0.3397 0.4571 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F01 compound treatment 131920.0 17900.0 0.55 122720.0 -7020.0 -0.18 0.2626 0.4503 1936929 CHDI2_000808 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F02 compound treatment 72400.0 -41600.0 -1.29 66840.0 -62900.0 -1.63 -2.0681 -0.9932 3552769 CHDI2_000809 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F03 compound treatment 93640.0 -20400.0 -0.63 82160.0 -47600.0 -1.24 -1.3213 -0.9515 3553741 CHDI2_000810 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Br)s2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F04 compound treatment 49360.0 -64700.0 -2.0 22240.0 -108000.0 -2.79 -3.3923 -0.9867 3554032 CHDI2_000811 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F05 compound treatment 112600.0 -1450.0 -0.04 102160.0 -27600.0 -0.72 -0.5384 -0.7498 3553745 CHDI2_000812 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F06 compound treatment 113560.0 -486.0 -0.02 101760.0 -28000.0 -0.73 -0.5247 -0.7216 3554034 CHDI2_000813 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F07 compound treatment 19040.0 -95000.0 -2.94 14480.0 -115000.0 -2.99 -4.1992 -1.0 3553748 CHDI2_000814 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F08 compound treatment 104040.0 -10000.0 -0.31 113880.0 -15900.0 -0.41 -0.5106 -0.9901 3554036 CHDI2_000815 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F09 compound treatment 109560.0 -4490.0 -0.14 96440.0 -33300.0 -0.87 -0.7101 -0.8103 3552725 CHDI2_000816 O=C(N/N=C/c1ccc(cc1)n2ccnc2)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F10 compound treatment 110840.0 -3210.0 -0.1 98600.0 -31100.0 -0.81 -0.6424 -0.788 3552771 CHDI2_000817 O=C(N/N=C/c1cccc(Oc2ccccc2)c1)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F11 compound treatment 105040.0 -9010.0 -0.28 105520.0 -24200.0 -0.63 -0.6423 -0.933 3553752 CHDI2_000818 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F12 compound treatment 125520.0 11500.0 0.36 101320.0 -28400.0 -0.74 -0.2708 -0.3304 3554038 CHDI2_000819 Cc1ncc(CO)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F13 compound treatment 109040.0 -5010.0 -0.16 109640.0 -20100.0 -0.52 -0.479 -0.8791 3553756 CHDI2_000820 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F14 compound treatment 111680.0 -2370.0 -0.07 103680.0 -26100.0 -0.68 -0.5307 -0.7791 3554040 CHDI2_000821 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F15 compound treatment 111120.0 -2930.0 -0.09 98960.0 -30800.0 -0.8 -0.6297 -0.7822 3553759 CHDI2_000822 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F16 compound treatment 69280.0 -44800.0 -1.39 72440.0 -57300.0 -1.49 -2.0336 -0.9994 3554042 CHDI2_000823 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F17 compound treatment 112320.0 -1730.0 -0.05 134520.0 4780.0 0.12 0.05 0.3697 3552730 CHDI2_000824 O=C(N/N=C/c1c[nH]c2ccccc12)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F18 compound treatment 83720.0 -30300.0 -0.94 80840.0 -48900.0 -1.27 -1.5629 -0.989 3552773 CHDI2_000825 O=C(N/N=C/c1cn(c2ccccc12)S(=O)(=O)c3ccccc3)c4ccccn4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F19 compound treatment 135880.0 21800.0 0.68 123840.0 -5900.0 -0.15 0.3699 0.5333 3553763 CHDI2_000826 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(c2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F20 compound treatment 86480.0 -27600.0 -0.85 73440.0 -56300.0 -1.46 -1.6384 -0.9672 3554044 CHDI2_000827 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F21 compound treatment 120000.0 5950.0 0.18 131640.0 1900.0 0.05 0.1653 0.8657 3553767 CHDI2_000828 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F22 compound treatment 117920.0 3870.0 0.12 126720.0 -3020.0 -0.08 0.0294 0.2046 3554046 CHDI2_000829 CCCCCCC/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F23 mock treatment 129400.0 15400.0 0.48 138640.0 8900.0 0.23 0.4999 0.945 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 F24 mock treatment 129200.0 15200.0 0.47 107960.0 -21800.0 -0.57 -0.0682 -0.0927 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G01 compound treatment 83760.0 -30300.0 -0.94 92760.0 -37000.0 -0.96 -1.343 -0.9999 3215102 CHDI2_000830 ONC(=O)CCCCC(=O)N/N=C/c1cccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G02 compound treatment 129000.0 15000.0 0.46 120760.0 -8980.0 -0.23 0.1626 0.3134 3553111 CHDI2_000831 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccccc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G03 compound treatment 119320.0 5270.0 0.16 141360.0 11600.0 0.3 0.329 0.9585 3553531 CHDI2_000832 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G04 compound treatment 121440.0 7390.0 0.23 119080.0 -10700.0 -0.28 -0.0339 -0.0943 3553612 CHDI2_000833 Cn1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G05 compound treatment 85600.0 -28400.0 -0.88 78080.0 -51700.0 -1.34 -1.5724 -0.9792 3215106 CHDI2_000834 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G06 compound treatment 103120.0 -10900.0 -0.34 96640.0 -33100.0 -0.86 -0.8476 -0.9169 3553115 CHDI2_000835 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccnc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G07 compound treatment 104240.0 -9810.0 -0.3 96880.0 -32900.0 -0.85 -0.8186 -0.9032 3215110 CHDI2_000836 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G08 compound treatment 103000.0 -11000.0 -0.34 99200.0 -30500.0 -0.79 -0.8031 -0.9293 3553118 CHDI2_000837 ONC(=O)c1cccc(c1)C(=O)N/N=C/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G09 compound treatment 97120.0 -16900.0 -0.52 91360.0 -38400.0 -1.0 -1.076 -0.955 3215114 CHDI2_000838 ONC(=O)CCCCC(=O)N/N=C/c1c(O)cc(O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G10 compound treatment 106880.0 -7170.0 -0.22 97720.0 -32000.0 -0.83 -0.7453 -0.8655 3553123 CHDI2_000839 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G11 compound treatment 112880.0 -1170.0 -0.04 102520.0 -27200.0 -0.71 -0.5257 -0.7422 3215118 CHDI2_000840 COc1cc(OC)c(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G12 compound treatment 106360.0 -7690.0 -0.24 102000.0 -27700.0 -0.72 -0.6781 -0.8932 3553127 CHDI2_000841 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G13 compound treatment 104840.0 -9210.0 -0.29 99880.0 -29900.0 -0.78 -0.7503 -0.9077 3215122 CHDI2_000842 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G14 compound treatment 109480.0 -4570.0 -0.14 102400.0 -27300.0 -0.71 -0.6024 -0.8316 3553128 CHDI2_000843 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(C#N)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G15 compound treatment 117400.0 3350.0 0.1 113800.0 -15900.0 -0.41 -0.2194 -0.5138 3215126 CHDI2_000844 CC(C)(C)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G16 compound treatment 102440.0 -11600.0 -0.36 102480.0 -27300.0 -0.71 -0.7552 -0.9506 3553133 CHDI2_000845 ONC(=O)c1cccc(c1)C(=O)N/N=C/C2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G17 compound treatment 104400.0 -9650.0 -0.3 117760.0 -12000.0 -0.31 -0.4315 -0.9998 3215130 CHDI2_000846 CC1=C(C/C=N/NC(=O)CCCCC(=O)NO)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G18 compound treatment 124400.0 10400.0 0.32 118440.0 -11300.0 -0.29 0.0192 0.0442 3553137 CHDI2_000847 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G19 compound treatment 113560.0 -486.0 -0.02 136880.0 7140.0 0.19 0.1205 0.6476 3553533 CHDI2_000848 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G20 compound treatment 122600.0 8550.0 0.27 135200.0 5460.0 0.14 0.2877 0.957 3553614 CHDI2_000849 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G21 compound treatment 116680.0 2630.0 0.08 136680.0 6940.0 0.18 0.1852 0.9358 3215134 CHDI2_000850 NC(=O)COc1ccccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G22 compound treatment 14720.0 -99300.0 -3.08 13920.0 -116000.0 -3.01 -4.3041 -0.9999 3553141 CHDI2_000851 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G23 mock treatment 112600.0 -1450.0 -0.04 122360.0 -7380.0 -0.19 -0.1673 -0.8494 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 G24 mock treatment 105560.0 -8490.0 -0.26 117120.0 -12600.0 -0.33 -0.4178 -0.994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H01 compound treatment 83640.0 -30400.0 -0.94 85960.0 -43800.0 -1.14 -1.4706 -0.9956 3553774 CHDI2_000852 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccccc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H02 compound treatment 95360.0 -18700.0 -0.58 94480.0 -35300.0 -0.92 -1.0573 -0.9755 3554050 CHDI2_000853 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H03 compound treatment 108800.0 -5250.0 -0.16 99160.0 -30600.0 -0.79 -0.6768 -0.8345 3552734 CHDI2_000854 Ic1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H04 compound treatment 132320.0 18300.0 0.57 98200.0 -31500.0 -0.82 -0.1791 -0.1798 3552775 CHDI2_000855 O=C(N/N=C/c1ccccn1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H05 compound treatment 102240.0 -11800.0 -0.37 94880.0 -34900.0 -0.91 -0.8992 -0.9204 3553778 CHDI2_000856 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccnc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H06 compound treatment 97400.0 -16600.0 -0.52 90240.0 -39500.0 -1.03 -1.0905 -0.9493 3554054 CHDI2_000857 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H07 compound treatment 84520.0 -29500.0 -0.91 72720.0 -57000.0 -1.48 -1.6945 -0.9732 3553782 CHDI2_000858 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H08 compound treatment 115560.0 1510.0 0.05 117000.0 -12700.0 -0.33 -0.2009 -0.6009 3554058 CHDI2_000859 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c(O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H09 compound treatment 108680.0 -5370.0 -0.17 106120.0 -23600.0 -0.61 -0.5516 -0.8674 3553785 CHDI2_000860 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H10 compound treatment 94720.0 -19300.0 -0.6 87400.0 -42300.0 -1.1 -1.2014 -0.9591 3554062 CHDI2_000861 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2c(O)cc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H11 compound treatment 115600.0 1550.0 0.05 93240.0 -36500.0 -0.95 -0.6366 -0.6703 3553788 CHDI2_000862 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H12 compound treatment 119080.0 5030.0 0.16 114720.0 -15000.0 -0.39 -0.1657 -0.3942 3554066 CHDI2_000863 COc1cc(OC)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H13 compound treatment 97640.0 -16400.0 -0.51 101000.0 -28700.0 -0.75 -0.8875 -0.9824 3553791 CHDI2_000864 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(C#N)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H14 compound treatment 104440.0 -9610.0 -0.3 105000.0 -24700.0 -0.64 -0.665 -0.9387 3554070 CHDI2_000865 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H15 compound treatment 107920.0 -6130.0 -0.19 104480.0 -25300.0 -0.66 -0.5983 -0.8757 3553793 CHDI2_000866 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H16 compound treatment 122960.0 8910.0 0.28 102800.0 -26900.0 -0.7 -0.2997 -0.3982 3554074 CHDI2_000867 CC(C)(C)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H17 compound treatment 71240.0 -42800.0 -1.33 77840.0 -51900.0 -1.35 -1.8914 -1.0 3553797 CHDI2_000868 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H18 compound treatment 110120.0 -3930.0 -0.12 103760.0 -26000.0 -0.68 -0.5634 -0.8213 3554078 CHDI2_000869 CC1=C(C/C=N/NC(=O)c2ccc(cc2)C(=O)NO)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H19 compound treatment 108120.0 -5930.0 -0.18 104320.0 -25400.0 -0.66 -0.5969 -0.8706 3552737 CHDI2_000870 C/C=C(/C)\C=N\NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H20 compound treatment 99640.0 -14400.0 -0.45 135120.0 5380.0 0.14 -0.2168 -0.4636 3552777 CHDI2_000871 O=C(N/N=C/c1cccnc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H21 compound treatment 16240.0 -97800.0 -3.03 17400.0 -112000.0 -2.92 -4.2069 -0.9998 3553801 CHDI2_000872 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H22 compound treatment 109160.0 -4890.0 -0.15 135920.0 6180.0 0.16 0.0065 0.0293 3554082 CHDI2_000873 NC(=O)COc1ccccc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H23 mock treatment 119000.0 4950.0 0.15 120280.0 -9460.0 -0.25 -0.0653 -0.2253 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 H24 mock treatment 94440.0 -19600.0 -0.61 107040.0 -22700.0 -0.59 -0.8466 -0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I01 compound treatment 88360.0 -25700.0 -0.8 120960.0 -8780.0 -0.23 -0.7241 -0.8746 3215181 CHDI2_000874 ONC(=O)CCCCC(=O)NN=C1CCCCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I02 compound treatment 118280.0 4230.0 0.13 140080.0 10300.0 0.27 0.2827 0.9457 3553148 CHDI2_000875 COc1cc(Cl)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I03 compound treatment 106160.0 -7890.0 -0.24 114240.0 -15500.0 -0.4 -0.4576 -0.9713 3215183 CHDI2_000876 ONC(=O)CCCCC(=O)NN=C1CCCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I04 compound treatment 22960.0 -91100.0 -2.82 20600.0 -109000.0 -2.84 -4.0009 -1.0 3553152 CHDI2_000877 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I05 compound treatment 37960.0 -76100.0 -2.36 30480.0 -99300.0 -2.58 -3.4907 -0.999 3553537 CHDI2_000878 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I06 compound treatment 112320.0 -1730.0 -0.05 119840.0 -9900.0 -0.26 -0.2197 -0.8362 3553618 CHDI2_000879 ONC(=O)c1cccc(c1)C(=O)N/N=C/C2=CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I07 compound treatment 106160.0 -7890.0 -0.24 111000.0 -18700.0 -0.49 -0.5171 -0.9491 3215185 CHDI2_000880 ONC(=O)CCCCC(=O)NN=C1CCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I08 compound treatment 112920.0 -1130.0 -0.03 114760.0 -15000.0 -0.39 -0.2999 -0.7674 3553156 CHDI2_000881 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I09 compound treatment 107600.0 -6450.0 -0.2 91960.0 -37800.0 -0.98 -0.8354 -0.8339 3214824 CHDI2_000882 NNC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I10 compound treatment 23760.0 -90300.0 -2.8 22600.0 -107000.0 -2.78 -3.9466 -1.0 3553212 CHDI2_000883 CCN(CC)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I11 compound treatment 24440.0 -89600.0 -2.78 23400.0 -106000.0 -2.76 -3.917 -1.0 3215188 CHDI2_000884 COc1cc(Br)c(/C=N/NC(=O)CCCCC(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I12 compound treatment 118960.0 4910.0 0.15 95400.0 -34300.0 -0.89 -0.5233 -0.5781 3553216 CHDI2_000885 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3OCCc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I13 compound treatment 110680.0 -3370.0 -0.1 105800.0 -23900.0 -0.62 -0.5136 -0.8143 3215192 CHDI2_000886 ONC(=O)CCCCC(=O)N/N=C/CCC1CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I14 compound treatment 87040.0 -27000.0 -0.84 95640.0 -34100.0 -0.89 -1.2182 -0.9996 3553220 CHDI2_000887 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I15 compound treatment 9560.0 -104000.0 -3.24 10200.0 -120000.0 -3.11 -4.4855 -0.9998 3215196 CHDI2_000888 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I16 compound treatment 116480.0 2430.0 0.08 129640.0 -103.0 0.0 0.0515 0.6817 3553224 CHDI2_000889 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I17 compound treatment 110320.0 -3730.0 -0.12 109480.0 -20300.0 -0.53 -0.4539 -0.8421 3215200 CHDI2_000890 ONC(=O)CCCCC(=O)N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I18 compound treatment 108640.0 -5410.0 -0.17 126680.0 -3060.0 -0.08 -0.1747 -0.9421 3553228 CHDI2_000891 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(O)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I19 compound treatment 116560.0 2510.0 0.08 112040.0 -17700.0 -0.46 -0.2702 -0.5791 3214824 CHDI2_000892 NNC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I20 compound treatment 121280.0 7230.0 0.22 113320.0 -16400.0 -0.43 -0.1432 -0.2971 3553231 CHDI2_000893 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I21 compound treatment 123680.0 9630.0 0.3 108240.0 -21500.0 -0.56 -0.184 -0.2904 3553541 CHDI2_000894 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I22 compound treatment 139640.0 25600.0 0.79 117600.0 -12100.0 -0.32 0.3377 0.3956 3553622 CHDI2_000895 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I23 mock treatment 111280.0 -2770.0 -0.09 125440.0 -4300.0 -0.11 -0.1396 -0.9914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 I24 mock treatment 108200.0 -5850.0 -0.18 95640.0 -34100.0 -0.89 -0.7546 -0.8344 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J01 compound treatment 75040.0 -39000.0 -1.21 111880.0 -17900.0 -0.46 -1.1828 -0.9136 3553809 CHDI2_000896 COc1cc(Cl)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J02 compound treatment 99120.0 -14900.0 -0.46 132920.0 3180.0 0.08 -0.2686 -0.5718 3554238 CHDI2_000897 ONC(=O)c1ccc(cc1)C(=O)NN=C2CCCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J03 compound treatment 47120.0 -66900.0 -2.07 37080.0 -92700.0 -2.41 -3.1687 -0.9972 3553812 CHDI2_000898 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J04 compound treatment 124600.0 10600.0 0.33 115560.0 -14200.0 -0.37 -0.0293 -0.0595 3554236 CHDI2_000899 ONC(=O)c1ccc(cc1)C(=O)NN=C2CCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J05 compound treatment 116200.0 2150.0 0.07 97120.0 -32600.0 -0.85 -0.5522 -0.6494 3552741 CHDI2_000900 [O-][N+](=O)c1ccc(/C=N/NC(=O)c2ccccn2)s1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J06 compound treatment 103840.0 -10200.0 -0.32 100720.0 -29000.0 -0.75 -0.7568 -0.9255 3552779 CHDI2_000901 Cc1ncc(CO)c(/C=N/NC(=O)c2ccccn2)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J07 compound treatment 109200.0 -4850.0 -0.15 108920.0 -20800.0 -0.54 -0.4887 -0.8704 3553816 CHDI2_000902 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J08 compound treatment 99240.0 -14800.0 -0.46 96040.0 -33700.0 -0.88 -0.9436 -0.9545 3554206 CHDI2_000903 ONC(=O)c1ccc(cc1)C(=O)N/N=C/Cc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J09 compound treatment 21480.0 -92600.0 -2.87 21600.0 -108000.0 -2.81 -4.0149 -0.9999 3553820 CHDI2_000904 CCN(CC)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J10 compound treatment 111000.0 -3050.0 -0.09 97880.0 -31900.0 -0.83 -0.6521 -0.7826 3554209 CHDI2_000905 COC(=O)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J11 compound treatment 88360.0 -25700.0 -0.8 89280.0 -40500.0 -1.05 -1.3062 -0.9906 3553823 CHDI2_000906 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3OCCc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J12 compound treatment 105360.0 -8690.0 -0.27 103080.0 -26700.0 -0.69 -0.6802 -0.9152 3554090 CHDI2_000907 COc1cc(Br)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J13 compound treatment 84000.0 -30000.0 -0.93 86600.0 -43100.0 -1.12 -1.4509 -0.9957 3553827 CHDI2_000908 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(O)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J14 compound treatment 94360.0 -19700.0 -0.61 108360.0 -21400.0 -0.56 -0.8241 -0.9989 3554213 CHDI2_000909 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc3ccccc3n2S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J15 compound treatment 83840.0 -30200.0 -0.94 93960.0 -35800.0 -0.93 -1.3192 -1.0 3553831 CHDI2_000910 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J16 compound treatment 10120.0 -104000.0 -3.22 11640.0 -118000.0 -3.07 -4.4468 -0.9997 3554094 CHDI2_000911 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J17 compound treatment 104800.0 -9250.0 -0.29 128800.0 -943.0 -0.02 -0.2199 -0.7648 3553835 CHDI2_000912 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(O)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J18 compound treatment 97320.0 -16700.0 -0.52 106840.0 -22900.0 -0.6 -0.7872 -0.9976 3554098 CHDI2_000913 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J19 compound treatment 108760.0 -5290.0 -0.16 115520.0 -14200.0 -0.37 -0.3771 -0.933 3553839 CHDI2_000914 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J20 compound treatment 118600.0 4550.0 0.14 96920.0 -32800.0 -0.85 -0.5032 -0.5822 3554217 CHDI2_000915 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J21 compound treatment 104040.0 -10000.0 -0.31 105360.0 -24400.0 -0.63 -0.6672 -0.9459 3552745 CHDI2_000916 Cc1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J22 compound treatment 112600.0 -1450.0 -0.04 108640.0 -21100.0 -0.55 -0.4194 -0.7623 1936582 CHDI2_000917 O=C(N/N=C/c1ccc[nH]1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J23 mock treatment 115080.0 1030.0 0.03 122560.0 -7180.0 -0.19 -0.1093 -0.5772 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 J24 mock treatment 107200.0 -6850.0 -0.21 109880.0 -19900.0 -0.52 -0.5149 -0.9228 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K01 compound treatment 70640.0 -43400.0 -1.34 150880.0 21100.0 0.55 -0.5626 -0.3873 3215240 CHDI2_000918 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K02 compound treatment 110440.0 -3610.0 -0.11 142320.0 12600.0 0.33 0.1521 0.4404 3553239 CHDI2_000919 COc1cccc(OC)c1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K03 compound treatment 113000.0 -1050.0 -0.03 110920.0 -18800.0 -0.49 -0.3687 -0.7523 3215244 CHDI2_000920 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K04 compound treatment 104520.0 -9530.0 -0.3 95160.0 -34600.0 -0.9 -0.8441 -0.8925 3553243 CHDI2_000921 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K05 compound treatment 105040.0 -9010.0 -0.28 94520.0 -35200.0 -0.92 -0.8444 -0.8826 3215248 CHDI2_000922 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K06 compound treatment 112840.0 -1210.0 -0.04 103840.0 -25900.0 -0.67 -0.5023 -0.7452 3553247 CHDI2_000923 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K07 compound treatment 99760.0 -14300.0 -0.44 98320.0 -31400.0 -0.82 -0.8903 -0.9586 3553544 CHDI2_000924 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3ccccc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K08 compound treatment 105000.0 -9050.0 -0.28 96480.0 -33300.0 -0.86 -0.8093 -0.8907 3553623 CHDI2_000925 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K09 compound treatment 112040.0 -2010.0 -0.06 96320.0 -33400.0 -0.87 -0.658 -0.7558 3215251 CHDI2_000926 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K10 compound treatment 113400.0 -646.0 -0.02 94280.0 -35500.0 -0.92 -0.6657 -0.7223 3553250 CHDI2_000927 CC1(C)COC(CCC/C=N/NC(=O)c2cccc(c2)C(=O)NO)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K11 compound treatment 112840.0 -1210.0 -0.04 93800.0 -35900.0 -0.93 -0.6868 -0.7348 3215253 CHDI2_000928 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K12 compound treatment 96360.0 -17700.0 -0.55 85880.0 -43900.0 -1.14 -1.1933 -0.9437 3553254 CHDI2_000929 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3cccc(c3)C(=O)NO)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K13 compound treatment 98520.0 -15500.0 -0.48 96360.0 -33400.0 -0.87 -0.9535 -0.9613 3215256 CHDI2_000930 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K14 compound treatment 97800.0 -16200.0 -0.5 116960.0 -12800.0 -0.33 -0.5908 -0.9796 3553258 CHDI2_000931 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)cs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K15 compound treatment 117480.0 3430.0 0.11 117200.0 -12500.0 -0.33 -0.1552 -0.4527 3553549 CHDI2_000932 Cc1ccccc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K16 compound treatment 111560.0 -2490.0 -0.08 89680.0 -40100.0 -1.04 -0.7905 -0.7574 3553627 CHDI2_000933 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2cccc(c2)C(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K17 compound treatment 47880.0 -66200.0 -2.05 75560.0 -54200.0 -1.41 -2.4451 -0.9832 3215260 CHDI2_000934 ONC(=O)CCCCC(=O)N/N=C/c1ccc(Oc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K18 compound treatment 115720.0 1670.0 0.05 107880.0 -21900.0 -0.57 -0.365 -0.6399 3553262 CHDI2_000935 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K19 compound treatment 104600.0 -9450.0 -0.29 106960.0 -22800.0 -0.59 -0.6255 -0.9473 3215264 CHDI2_000936 ONC(=O)CCCCC(=O)N/N=C/c1cc[n+]([O-])cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K20 compound treatment 25000.0 -89000.0 -2.76 28320.0 -101000.0 -2.64 -3.8143 -0.9997 3553266 CHDI2_000937 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K21 compound treatment 72040.0 -42000.0 -1.3 86120.0 -43600.0 -1.13 -1.7218 -0.9976 3215268 CHDI2_000938 ONC(=O)CCCCC(=O)N/N=C/c1ccc2ccccc2n1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K22 compound treatment 104280.0 -9770.0 -0.3 107000.0 -22700.0 -0.59 -0.6318 -0.9517 3553269 CHDI2_000939 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(F)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K23 mock treatment 117800.0 3750.0 0.12 108640.0 -21100.0 -0.55 -0.3055 -0.545 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 K24 mock treatment 95280.0 -18800.0 -0.58 138320.0 8580.0 0.22 -0.2535 -0.4072 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L01 compound treatment 64720.0 -49300.0 -1.53 102000.0 -27700.0 -0.72 -1.5904 -0.9412 3553847 CHDI2_000940 COc1cccc(OC)c1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L02 compound treatment 116960.0 2910.0 0.09 141600.0 11900.0 0.31 0.2817 0.8774 3554102 CHDI2_000941 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L03 compound treatment 93520.0 -20500.0 -0.64 125240.0 -4500.0 -0.12 -0.5324 -0.8234 3553851 CHDI2_000942 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L04 compound treatment 102720.0 -11300.0 -0.35 98360.0 -31400.0 -0.82 -0.8247 -0.929 3554105 CHDI2_000943 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L05 compound treatment 120200.0 6150.0 0.19 99760.0 -30000.0 -0.78 -0.416 -0.5187 3553855 CHDI2_000944 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L06 compound treatment 109080.0 -4970.0 -0.15 85640.0 -44100.0 -1.15 -0.9191 -0.7949 3554109 CHDI2_000945 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L07 compound treatment 31720.0 -82300.0 -2.55 28920.0 -101000.0 -2.62 -3.6561 -0.9999 3552749 CHDI2_000946 Cc1[nH]cnc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L08 compound treatment 89440.0 -24600.0 -0.76 96640.0 -33100.0 -0.86 -1.1473 -0.9982 3552781 CHDI2_000947 O=C(N/N=C/c1ccc(cc1)N2CCCC2)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L09 compound treatment 102360.0 -11700.0 -0.36 86760.0 -43000.0 -1.12 -1.0457 -0.8907 3553858 CHDI2_000948 CC1(C)COC(CCC/C=N/NC(=O)c2ccc(cc2)C(=O)NO)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L10 compound treatment 104480.0 -9570.0 -0.3 86840.0 -42900.0 -1.11 -0.9978 -0.8651 3554113 CHDI2_000949 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L11 compound treatment 105720.0 -8330.0 -0.26 101720.0 -28000.0 -0.73 -0.6973 -0.9027 3553862 CHDI2_000950 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3ccc(cc3)C(=O)NO)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L12 compound treatment 105200.0 -8850.0 -0.27 88880.0 -40900.0 -1.06 -0.9446 -0.8614 3554115 CHDI2_000951 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L13 compound treatment 76600.0 -37400.0 -1.16 76760.0 -53000.0 -1.38 -1.7938 -0.9964 3553866 CHDI2_000952 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L14 compound treatment 108360.0 -5690.0 -0.18 90600.0 -39100.0 -1.02 -0.8437 -0.8174 3554117 CHDI2_000953 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L15 compound treatment 92160.0 -21900.0 -0.68 83160.0 -46600.0 -1.21 -1.3353 -0.9625 3552753 CHDI2_000954 Cc1ccsc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L16 compound treatment 91800.0 -22200.0 -0.69 97200.0 -32500.0 -0.85 -1.0853 -0.9949 3552783 CHDI2_000955 Oc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L17 compound treatment 100000.0 -14000.0 -0.44 96120.0 -33600.0 -0.87 -0.9255 -0.9482 3553870 CHDI2_000956 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L18 compound treatment 32080.0 -82000.0 -2.54 33400.0 -96300.0 -2.5 -3.5659 -1.0 3554121 CHDI2_000957 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L19 compound treatment 83680.0 -30400.0 -0.94 95880.0 -33900.0 -0.88 -1.2874 -0.9994 3553873 CHDI2_000958 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L20 compound treatment 102000.0 -12000.0 -0.37 82560.0 -47200.0 -1.23 -1.1308 -0.8824 3554125 CHDI2_000959 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L21 compound treatment 88480.0 -25600.0 -0.79 108160.0 -21600.0 -0.56 -0.9567 -0.9857 3553877 CHDI2_000960 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(F)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L22 compound treatment 83240.0 -30800.0 -0.95 87880.0 -41900.0 -1.09 -1.4441 -0.9979 3554129 CHDI2_000961 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3ccccc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L23 mock treatment 115040.0 994.0 0.03 114400.0 -15300.0 -0.4 -0.2601 -0.6505 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 L24 mock treatment 95040.0 -19000.0 -0.59 130520.0 778.0 0.02 -0.4021 -0.6824 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M01 compound treatment 38640.0 -75400.0 -2.34 58520.0 -71200.0 -1.85 -2.9606 -0.9933 3215312 CHDI2_000962 Cc1ccccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M02 compound treatment 113720.0 -326.0 -0.01 131560.0 1820.0 0.05 0.0263 0.5438 3553273 CHDI2_000963 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)c(F)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M03 compound treatment 81400.0 -32600.0 -1.01 98880.0 -30900.0 -0.8 -1.2823 -0.9934 3215316 CHDI2_000964 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M04 compound treatment 64800.0 -49200.0 -1.53 77440.0 -52300.0 -1.36 -2.0399 -0.9983 3553277 CHDI2_000965 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M05 compound treatment 101760.0 -12300.0 -0.38 93160.0 -36600.0 -0.95 -0.9413 -0.9193 3215320 CHDI2_000966 ONC(=O)CCCCC(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M06 compound treatment 62200.0 -51800.0 -1.61 42080.0 -87700.0 -2.28 -2.7465 -0.9854 3553281 CHDI2_000967 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(F)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M07 compound treatment 114040.0 -5.52 0.0 93840.0 -35900.0 -0.93 -0.6597 -0.7072 3215323 CHDI2_000968 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M08 compound treatment 107560.0 -6490.0 -0.2 102960.0 -26800.0 -0.7 -0.6342 -0.8755 3553285 CHDI2_000969 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M09 compound treatment 112040.0 -2010.0 -0.06 105840.0 -23900.0 -0.62 -0.4831 -0.774 3553579 CHDI2_000970 ONC(=O)c1cccc(c1)C(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M10 compound treatment 104240.0 -9810.0 -0.3 129720.0 -22.5 0.0 -0.2152 -0.7085 3553631 CHDI2_000971 CN(C)CCCOc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M11 compound treatment 96680.0 -17400.0 -0.54 87480.0 -42300.0 -1.1 -1.1569 -0.9461 3215326 CHDI2_000972 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M12 compound treatment 128120.0 14100.0 0.44 107560.0 -22200.0 -0.58 -0.0992 -0.1372 3553289 CHDI2_000973 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M13 compound treatment 103280.0 -10800.0 -0.33 108720.0 -21000.0 -0.55 -0.6221 -0.972 3553584 CHDI2_000974 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M14 compound treatment 103360.0 -10700.0 -0.33 97920.0 -31800.0 -0.83 -0.8188 -0.9193 3553635 CHDI2_000975 CCOc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M15 compound treatment 48560.0 -65500.0 -2.03 68520.0 -61200.0 -1.59 -2.5596 -0.9927 3215330 CHDI2_000976 CCOc1cccc(/C=N/NC(=O)CCCCC(=O)NO)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M16 compound treatment 107440.0 -6610.0 -0.2 103040.0 -26700.0 -0.69 -0.6353 -0.8783 3553293 CHDI2_000977 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(c2)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M17 compound treatment 12080.0 -102000.0 -3.16 18320.0 -111000.0 -2.9 -4.2811 -0.999 3215334 CHDI2_000978 ONC(=O)CCCCC(=O)N/N=C/c1cc(I)cc(I)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M18 compound treatment 120400.0 6350.0 0.2 104080.0 -25700.0 -0.67 -0.3323 -0.4779 3553297 CHDI2_000979 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccco2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M19 compound treatment 83600.0 -30400.0 -0.94 98680.0 -31100.0 -0.81 -1.2377 -0.997 3215338 CHDI2_000980 CN(C)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M20 compound treatment 120760.0 6710.0 0.21 101720.0 -28000.0 -0.73 -0.3677 -0.4856 3553301 CHDI2_000981 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccoc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M21 compound treatment 12800.0 -101000.0 -3.14 20120.0 -110000.0 -2.85 -4.2323 -0.9988 3215342 CHDI2_000982 CCn1c2ccccc2c3cc(/C=N/NC(=O)CCCCC(=O)NO)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M22 compound treatment 103560.0 -10500.0 -0.32 108840.0 -20900.0 -0.54 -0.6138 -0.9698 3553305 CHDI2_000983 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M23 mock treatment 111960.0 -2090.0 -0.06 123280.0 -6460.0 -0.17 -0.1644 -0.9139 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 M24 mock treatment 99560.0 -14500.0 -0.45 141920.0 12200.0 0.32 -0.0936 -0.1705 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N01 compound treatment 70600.0 -43400.0 -1.35 109360.0 -20400.0 -0.53 -1.3263 -0.9169 3553880 CHDI2_000984 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)c(F)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N02 compound treatment 90600.0 -23400.0 -0.73 141040.0 11300.0 0.29 -0.3061 -0.3907 3554133 CHDI2_000985 Cc1ccccc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N03 compound treatment 41960.0 -72100.0 -2.23 61320.0 -68400.0 -1.78 -2.8364 -0.9936 3553882 CHDI2_000986 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N04 compound treatment 104920.0 -9130.0 -0.28 95560.0 -34200.0 -0.89 -0.828 -0.8883 3554137 CHDI2_000987 COc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N05 compound treatment 66640.0 -47400.0 -1.47 68560.0 -61200.0 -1.59 -2.1627 -0.9992 3553886 CHDI2_000988 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(F)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N06 compound treatment 100680.0 -13400.0 -0.41 89600.0 -40100.0 -1.04 -1.0304 -0.9181 3554141 CHDI2_000989 ONC(=O)c1ccc(cc1)C(=O)N/N=C/[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N07 compound treatment 97400.0 -16600.0 -0.52 94200.0 -35500.0 -0.92 -1.0177 -0.9621 3553889 CHDI2_000990 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N08 compound treatment 88520.0 -25500.0 -0.79 105920.0 -23800.0 -0.62 -0.9969 -0.9926 3554145 CHDI2_000991 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N09 compound treatment 104280.0 -9770.0 -0.3 101480.0 -28300.0 -0.73 -0.7332 -0.9232 3552757 CHDI2_000992 O=C(N/N=C/c1cccc2ccccc12)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N10 compound treatment 42000.0 -72000.0 -2.23 36440.0 -93300.0 -2.42 -3.2927 -0.9992 3552787 CHDI2_000993 O=C(N/N=C/c1nccs1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N11 compound treatment 89600.0 -24400.0 -0.76 104400.0 -25300.0 -0.66 -1.0012 -0.9976 3553894 CHDI2_000994 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N12 compound treatment 107240.0 -6810.0 -0.21 103000.0 -26700.0 -0.69 -0.6404 -0.882 3554147 CHDI2_000995 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N13 compound treatment 104600.0 -9450.0 -0.29 101360.0 -28400.0 -0.74 -0.7284 -0.9181 3552759 CHDI2_000996 O=C(N/N=C/c1ccc2ccccc2c1)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N14 compound treatment 101520.0 -12500.0 -0.39 106480.0 -23300.0 -0.6 -0.7018 -0.9771 3552789 CHDI2_000997 O=C(N/N=C/c1cccs1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N15 compound treatment 84760.0 -29300.0 -0.91 97960.0 -31800.0 -0.83 -1.2256 -0.9989 3553898 CHDI2_000998 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(c2)B(O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N16 compound treatment 72440.0 -41600.0 -1.29 99240.0 -30500.0 -0.79 -1.472 -0.9727 3554152 CHDI2_000999 CCOc1cccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N17 compound treatment 96840.0 -17200.0 -0.53 98480.0 -31300.0 -0.81 -0.9513 -0.9791 3553901 CHDI2_001000 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccco2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N18 compound treatment 10200.0 -104000.0 -3.22 12680.0 -117000.0 -3.04 -4.4259 -0.9996 3554155 CHDI2_001001 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N19 compound treatment 99400.0 -14600.0 -0.45 98080.0 -31700.0 -0.82 -0.9026 -0.9607 3553905 CHDI2_001002 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccoc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N20 compound treatment 68680.0 -45400.0 -1.41 98400.0 -31300.0 -0.81 -1.5698 -0.9663 3554159 CHDI2_001003 CN(C)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N21 compound treatment 94840.0 -19200.0 -0.6 101400.0 -28300.0 -0.74 -0.9415 -0.9944 3553909 CHDI2_001004 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N22 compound treatment 9480.0 -105000.0 -3.24 11320.0 -118000.0 -3.08 -4.4667 -0.9997 3554162 CHDI2_001005 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4ccc(cc4)C(=O)NO)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N23 mock treatment 108120.0 -5930.0 -0.18 124960.0 -4780.0 -0.12 -0.2177 -0.9819 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 N24 mock treatment 110000.0 -4050.0 -0.13 138480.0 8740.0 0.23 0.0719 0.2772 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O01 compound treatment 96120.0 -17900.0 -0.56 132720.0 2980.0 0.08 -0.338 -0.6028 3215394 CHDI2_001006 ONC(=O)CCCCC(=O)N/N=C/c1ccc(o1)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O02 compound treatment 94760.0 -19300.0 -0.6 149880.0 20100.0 0.52 -0.0526 -0.0662 3553313 CHDI2_001007 OCCOc1ccccc1/C=N/NC(=O)c2cccc(c2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O03 compound treatment 56560.0 -57500.0 -1.78 98800.0 -30900.0 -0.8 -1.828 -0.9354 3215398 CHDI2_001008 Cn1cc(/C=N/NC(=O)CCCCC(=O)NO)c2ccccc12 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O04 compound treatment 106560.0 -7490.0 -0.23 113280.0 -16500.0 -0.43 -0.4665 -0.9587 3553317 CHDI2_001009 OCCOc1cccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O05 compound treatment 12440.0 -102000.0 -3.15 16840.0 -113000.0 -2.93 -4.3004 -0.9994 3215402 CHDI2_001010 ONC(=O)CCCCC(=O)N/N=C/c1cn(Cc2ccccc2)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O06 compound treatment 103840.0 -10200.0 -0.32 104840.0 -24900.0 -0.65 -0.6811 -0.9458 3553320 CHDI2_001011 OCCOc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O07 compound treatment 70520.0 -43500.0 -1.35 98640.0 -31100.0 -0.81 -1.525 -0.97 3215406 CHDI2_001012 ONC(=O)CCCCC(=O)N/N=C/C1=CCCCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O08 compound treatment 40240.0 -73800.0 -2.29 31440.0 -98300.0 -2.55 -3.4231 -0.9985 3553323 CHDI2_001013 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O09 compound treatment 80680.0 -33400.0 -1.03 101200.0 -28500.0 -0.74 -1.2554 -0.9867 3215409 CHDI2_001014 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O10 compound treatment 74200.0 -39800.0 -1.23 72040.0 -57700.0 -1.5 -1.9331 -0.9953 3553327 CHDI2_001015 COc1ccc(O)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O11 compound treatment 101440.0 -12600.0 -0.39 97320.0 -32400.0 -0.84 -0.8719 -0.9389 3553585 CHDI2_001016 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O12 compound treatment 96040.0 -18000.0 -0.56 94160.0 -35600.0 -0.92 -1.0482 -0.9708 3553639 CHDI2_001017 CN(CCO)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O13 compound treatment 102360.0 -11700.0 -0.36 100440.0 -29300.0 -0.76 -0.7944 -0.9423 3215412 CHDI2_001018 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O14 compound treatment 96560.0 -17500.0 -0.54 103400.0 -26300.0 -0.68 -0.8671 -0.9933 3553331 CHDI2_001019 COc1cc(/C=C/C=N/NC(=O)c2cccc(c2)C(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O15 compound treatment 91040.0 -23000.0 -0.71 106280.0 -23500.0 -0.61 -0.9351 -0.997 3215416 CHDI2_001020 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)CCCCC(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O16 compound treatment 43440.0 -70600.0 -2.19 30920.0 -98800.0 -2.57 -3.3625 -0.9968 3553334 CHDI2_001021 Cc1ccc(O)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O17 compound treatment 84600.0 -29400.0 -0.91 98240.0 -31500.0 -0.82 -1.2239 -0.9985 3215420 CHDI2_001022 C/C(=N\NC(=O)CCCCC(=O)NO)/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O18 compound treatment 89800.0 -24200.0 -0.75 116040.0 -13700.0 -0.36 -0.783 -0.9418 3553338 CHDI2_001023 OCc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O19 compound treatment 91080.0 -23000.0 -0.71 100560.0 -29200.0 -0.76 -1.0393 -0.9995 3215424 CHDI2_001024 CN(C)CCCOc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O20 compound treatment 15840.0 -98200.0 -3.04 14480.0 -115000.0 -2.99 -4.2693 -1.0 3553342 CHDI2_001025 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc3ccccc3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O21 compound treatment 89360.0 -24700.0 -0.76 106200.0 -23500.0 -0.61 -0.9734 -0.9939 3215428 CHDI2_001026 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O22 compound treatment 47360.0 -66700.0 -2.07 52400.0 -77300.0 -2.01 -2.882 -0.9999 3553346 CHDI2_001027 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O23 mock treatment 99520.0 -14500.0 -0.45 134760.0 5020.0 0.13 -0.2261 -0.4824 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 O24 mock treatment 89880.0 -24200.0 -0.75 152840.0 23100.0 0.6 -0.1051 -0.1095 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P01 compound treatment 69800.0 -44200.0 -1.37 78040.0 -51700.0 -1.34 -1.9193 -0.9999 3553917 CHDI2_001028 OCCOc1ccccc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P02 compound treatment 93680.0 -20400.0 -0.63 132360.0 2620.0 0.07 -0.3981 -0.6273 3554170 CHDI2_001029 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P03 compound treatment 72040.0 -42000.0 -1.3 131800.0 2060.0 0.05 -0.8825 -0.6775 3553921 CHDI2_001030 OCCOc1cccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P04 compound treatment 54560.0 -59500.0 -1.84 93920.0 -35800.0 -0.93 -1.9614 -0.9499 3554174 CHDI2_001031 Cn1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P05 compound treatment 80200.0 -33800.0 -1.05 91720.0 -38000.0 -0.99 -1.4401 -0.9996 3553924 CHDI2_001032 OCCOc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P06 compound treatment 25320.0 -88700.0 -2.75 37280.0 -92500.0 -2.4 -3.6427 -0.9977 3554177 CHDI2_001033 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P07 compound treatment 33400.0 -80600.0 -2.5 38160.0 -91600.0 -2.38 -3.4495 -0.9997 3553927 CHDI2_001034 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P08 compound treatment 72480.0 -41600.0 -1.29 92120.0 -37600.0 -0.98 -1.6019 -0.9907 3554181 CHDI2_001035 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C2=CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P09 compound treatment 53240.0 -60800.0 -1.88 70280.0 -59500.0 -1.55 -2.4247 -0.9951 3553931 CHDI2_001036 COc1ccc(O)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P10 compound treatment 84920.0 -29100.0 -0.9 94000.0 -35700.0 -0.93 -1.2948 -0.9999 3554185 CHDI2_001037 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1ccc(cc1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P11 compound treatment 97440.0 -16600.0 -0.51 109520.0 -20200.0 -0.53 -0.7354 -0.9999 3552761 CHDI2_001038 [O-][N+](=O)c1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P12 compound treatment 92480.0 -21600.0 -0.67 89760.0 -40000.0 -1.04 -1.2071 -0.9772 3552791 CHDI2_001039 FC(F)(F)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P13 compound treatment 67640.0 -46400.0 -1.44 105960.0 -23800.0 -0.62 -1.4537 -0.9289 3553935 CHDI2_001040 COc1cc(/C=C/C=N/NC(=O)c2ccc(cc2)C(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P14 compound treatment 82320.0 -31700.0 -0.98 88560.0 -41200.0 -1.07 -1.4517 -0.9991 3554187 CHDI2_001041 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P15 compound treatment 43160.0 -70900.0 -2.2 69560.0 -60200.0 -1.56 -2.6588 -0.9861 3553938 CHDI2_001042 Cc1ccc(O)c(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P16 compound treatment 71280.0 -42800.0 -1.33 103600.0 -26100.0 -0.68 -1.4173 -0.9518 3554191 CHDI2_001043 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccc(cc2)C(=O)NO)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P17 compound treatment 77240.0 -36800.0 -1.14 94720.0 -35000.0 -0.91 -1.4498 -0.9937 3553942 CHDI2_001044 OCc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P18 compound treatment 60320.0 -53700.0 -1.66 94440.0 -35300.0 -0.92 -1.8257 -0.9606 3554251 CHDI2_001045 C/C(=N\NC(=O)c1ccc(cc1)C(=O)NO)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P19 compound treatment 7480.0 -107000.0 -3.3 7680.0 -122000.0 -3.17 -4.5774 -0.9998 3553946 CHDI2_001046 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc3ccccc3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P20 compound treatment 59920.0 -54100.0 -1.68 89040.0 -40700.0 -1.06 -1.9337 -0.9753 3554194 CHDI2_001047 CN(C)CCCOc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P21 compound treatment 51960.0 -62100.0 -1.92 71680.0 -58100.0 -1.51 -2.427 -0.9928 3553950 CHDI2_001048 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P22 compound treatment 70040.0 -44000.0 -1.36 95200.0 -34500.0 -0.9 -1.5988 -0.9794 3554198 CHDI2_001049 CCOc1cc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P23 mock treatment 96480.0 -17600.0 -0.54 116840.0 -12900.0 -0.34 -0.6219 -0.9729 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2405 P24 mock treatment 84120.0 -29900.0 -0.93 81880.0 -47900.0 -1.24 -1.535 -0.9895 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A01 compound treatment 70320.0 -34700.0 -1.07 82120.0 -38600.0 -1.0 -1.4692 -0.9994 1006361 CHDI2_001050 NNC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A02 compound treatment 21120.0 -83900.0 -2.6 17880.0 -103000.0 -2.67 -3.7274 -0.9999 3552205 CHDI2_001051 Oc1ccc2ccccc2c1/C=N/NC(=O)c3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A03 compound treatment 118920.0 13900.0 0.43 96840.0 -23900.0 -0.62 -0.134 -0.1774 3551925 CHDI2_001052 Oc1ccccc1C(=O)N/N=C/c2ccccc2OCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A04 compound treatment 164000.0 59000.0 1.83 126600.0 5880.0 0.15 1.4004 0.7635 3552209 CHDI2_001053 Oc1ccccc1C(=O)N/N=C/c2ccc(O)c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A05 compound treatment 157560.0 52600.0 1.63 107200.0 -13500.0 -0.35 0.9029 0.5421 1913714 CHDI2_001054 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A06 compound treatment 174480.0 69500.0 2.15 116640.0 -4080.0 -0.11 1.4471 0.6715 3552211 CHDI2_001055 Oc1ccccc1C(=O)N/N=C/c2ccc([N+](=O)[O-])c(O)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A07 compound treatment 172360.0 67400.0 2.09 102720.0 -18000.0 -0.47 1.1449 0.5353 3551931 CHDI2_001056 Oc1ccccc1C(=O)N/N=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A08 compound treatment 185720.0 80700.0 2.5 98960.0 -21800.0 -0.57 1.3685 0.5338 3552215 CHDI2_001057 Oc1ccc([N+](=O)[O-])c(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A09 compound treatment 164560.0 59600.0 1.85 79760.0 -41000.0 -1.06 0.5521 0.2592 3551934 CHDI2_001058 Oc1ccccc1C(=O)N/N=C/c2ccc3OCCOc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A10 compound treatment 164960.0 60000.0 1.86 85360.0 -35400.0 -0.92 0.6638 0.3203 3552219 CHDI2_001059 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)n3ccnc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A11 compound treatment 182520.0 77500.0 2.4 98080.0 -22600.0 -0.59 1.2822 0.5186 3551938 CHDI2_001060 Oc1ccccc1C(=O)N/N=C/COCc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A12 compound treatment 162840.0 57800.0 1.79 130400.0 9680.0 0.25 1.4448 0.7985 3552223 CHDI2_001061 Oc1ccccc1C(=O)N/N=C/c2c[nH]c3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A13 compound treatment 186320.0 81300.0 2.52 117320.0 -3400.0 -0.09 1.719 0.6819 3552793 CHDI2_001062 Oc1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A14 compound treatment 157400.0 52400.0 1.62 130960.0 10200.0 0.27 1.3359 0.8122 3552989 CHDI2_001063 OB(O)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A15 compound treatment 139040.0 34000.0 1.05 58040.0 -62700.0 -1.63 -0.406 -0.2093 3551942 CHDI2_001064 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A16 compound treatment 169920.0 64900.0 2.01 99480.0 -21200.0 -0.55 1.0319 0.4948 1922439 CHDI2_001065 Oc1ccccc1C(=O)N/N=C/c2ccc(I)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A17 compound treatment 168400.0 63400.0 1.96 114960.0 -5760.0 -0.15 1.283 0.6513 3551946 CHDI2_001066 Oc1ccccc1C(=O)N/N=C/c2ccccc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A18 compound treatment 162360.0 57400.0 1.78 147720.0 27000.0 0.7 1.7525 0.9174 3552228 CHDI2_001067 C/C=C(/C)\C=N\NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A19 compound treatment 172680.0 67700.0 2.1 133440.0 12700.0 0.33 1.7163 0.8086 3551950 CHDI2_001068 Oc1ccccc1C(=O)N/N=C/c2cccc(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A20 compound treatment 194440.0 89400.0 2.77 135360.0 14600.0 0.38 2.2283 0.7967 3552232 CHDI2_001069 Oc1ccccc1C(=O)N/N=C/c2ccc(s2)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A21 compound treatment 159600.0 54600.0 1.69 129960.0 9240.0 0.24 1.3658 0.7994 3551953 CHDI2_001070 Oc1ccccc1C(=O)N/N=C/c2ccc(Br)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A22 compound treatment 158760.0 53800.0 1.67 167720.0 47000.0 1.22 2.0411 0.9884 1912639 CHDI2_001071 Cc1ccc(/C=N/NC(=O)c2ccccc2O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A23 mock treatment 109560.0 4550.0 0.14 151920.0 31200.0 0.81 0.6729 0.8178 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 A24 mock treatment 75280.0 -29700.0 -0.92 84240.0 -36500.0 -0.95 -1.3216 -0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B01 compound treatment 124680.0 19700.0 0.61 99240.0 -21500.0 -0.56 0.0363 0.0439 1047348 CHDI2_001072 NNC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B02 compound treatment 15760.0 -89300.0 -2.77 18560.0 -102000.0 -2.65 -3.8324 -0.9998 3213096 CHDI2_001073 ONC(=O)CCCCCCC(=O)N/N=C/C(=C/c1ccccc1)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B03 compound treatment 174640.0 69600.0 2.16 128280.0 7560.0 0.2 1.6644 0.7683 3552424 CHDI2_001074 C=CCOc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B04 compound treatment 148880.0 43900.0 1.36 90840.0 -29900.0 -0.78 0.4122 0.2633 3213142 CHDI2_001075 Cc1[nH]cnc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B05 compound treatment 122200.0 17200.0 0.53 99480.0 -21200.0 -0.55 -0.0136 -0.0178 3552426 CHDI2_001076 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B06 compound treatment 12920.0 -92100.0 -2.85 7520.0 -113000.0 -2.94 -4.0974 -0.9999 3213098 CHDI2_001077 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B07 compound treatment 147760.0 42800.0 1.32 97720.0 -23000.0 -0.6 0.514 0.3537 3552428 CHDI2_001078 O=C(N/N=C/c1ccccc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B08 compound treatment 147480.0 42500.0 1.32 95920.0 -24800.0 -0.64 0.4748 0.3241 3213140 CHDI2_001079 Cc1[nH]cnc1/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B09 compound treatment 74520.0 -30500.0 -0.94 42320.0 -78400.0 -2.04 -2.1085 -0.939 3552430 CHDI2_001080 O=C(N/N=C/c1ccc2OCCOc2c1)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B10 compound treatment 102840.0 -2170.0 -0.07 97800.0 -22900.0 -0.6 -0.4687 -0.782 3214252 CHDI2_001081 ONC(=O)CCCCCC(=O)N/N=C/C(=C/c1ccccc1)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B11 compound treatment 141760.0 36800.0 1.14 106400.0 -14300.0 -0.37 0.5421 0.4525 3552432 CHDI2_001082 O=C(N/N=C/COCc1ccccc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B12 compound treatment 72680.0 -32300.0 -1.0 53400.0 -67300.0 -1.75 -1.9452 -0.965 3214254 CHDI2_001083 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B13 compound treatment 150320.0 45300.0 1.4 142520.0 21800.0 0.57 1.3932 0.9203 3552919 CHDI2_001084 CCOc1cccc(/C=N/NC(=O)c2ccccn2)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B14 compound treatment 156840.0 51800.0 1.61 129560.0 8840.0 0.23 1.298 0.8001 3214296 CHDI2_001085 Cc1[nH]cnc1/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B15 compound treatment 170960.0 66000.0 2.04 73720.0 -47000.0 -1.22 0.5814 0.2442 3552436 CHDI2_001086 O=C(N/N=C/c1ccc(cc1)c2ccccc2)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B16 compound treatment 141960.0 37000.0 1.14 25720.0 -95000.0 -2.47 -0.9359 -0.3439 3214862 CHDI2_001087 ONC(=O)CCCCC(=O)N/N=C/C(=C/c1ccccc1)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B17 compound treatment 162800.0 57800.0 1.79 138200.0 17500.0 0.45 1.5873 0.8592 3552440 CHDI2_001088 Brc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B18 compound treatment 170400.0 65400.0 2.03 114600.0 -6120.0 -0.16 1.3202 0.6496 3214908 CHDI2_001089 Cc1[nH]cnc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B19 compound treatment 170120.0 65100.0 2.02 159040.0 38300.0 1.0 2.1305 0.947 3552445 CHDI2_001090 Brc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B20 compound treatment 173360.0 68400.0 2.12 86720.0 -34000.0 -0.88 0.8728 0.3804 3553033 CHDI2_001091 ONC(=O)c1cccc(c1)C(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B21 compound treatment 163920.0 58900.0 1.83 124880.0 4160.0 0.11 1.3671 0.7477 3552449 CHDI2_001092 Brc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B22 compound treatment 72920.0 -32100.0 -0.99 57480.0 -63200.0 -1.64 -1.865 -0.971 3553699 CHDI2_001093 ONC(=O)c1ccc(cc1)C(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B23 mock treatment 181520.0 76500.0 2.37 136240.0 15500.0 0.4 1.9614 0.8157 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 B24 mock treatment 122240.0 17200.0 0.53 117960.0 -2760.0 -0.07 0.3268 0.6066 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C01 compound treatment 155360.0 50400.0 1.56 116080.0 -4640.0 -0.12 1.0179 0.6505 3551960 CHDI2_001094 Oc1ccccc1C(=O)N/N=C/c2ccc(Br)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C02 compound treatment 170280.0 65300.0 2.02 109000.0 -11700.0 -0.3 1.2147 0.5939 3552241 CHDI2_001095 Cc1ccsc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C03 compound treatment 171760.0 66800.0 2.07 103800.0 -16900.0 -0.44 1.1516 0.5446 3551964 CHDI2_001096 Oc1ccc(/C=N/NC(=O)c2ccccc2O)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C04 compound treatment 148600.0 43600.0 1.35 84800.0 -35900.0 -0.93 0.2951 0.1797 3552245 CHDI2_001097 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3ccccc3O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C05 compound treatment 152040.0 47000.0 1.46 98040.0 -22700.0 -0.59 0.6137 0.3904 3551968 CHDI2_001098 Oc1ccc(Br)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C06 compound treatment 128080.0 23100.0 0.71 79560.0 -41200.0 -1.07 -0.2508 -0.195 3552249 CHDI2_001099 Oc1ccccc1C(=O)N/N=C/c2cccc3ccccc23 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C07 compound treatment 21000.0 -84000.0 -2.6 15480.0 -105000.0 -2.73 -3.7742 -0.9997 3551973 CHDI2_001100 COc1cc(Br)cc(/C=N/NC(=O)c2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C08 compound treatment 151480.0 46500.0 1.44 131840.0 11100.0 0.29 1.2224 0.8324 3552253 CHDI2_001101 Oc1ccccc1C(=O)N/N=C/c2ccc3ccccc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C09 compound treatment 127040.0 22000.0 0.68 69160.0 -51600.0 -1.34 -0.4647 -0.309 3551976 CHDI2_001102 COc1ccc(Br)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C10 compound treatment 148320.0 43300.0 1.34 123320.0 2600.0 0.07 0.9966 0.7417 1918554 CHDI2_001103 Oc1ccccc1C(=O)N/N=C/c2ccccc2[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C11 compound treatment 92960.0 -12100.0 -0.37 65040.0 -55700.0 -1.45 -1.287 -0.8614 3552795 CHDI2_001104 Oc1cc(O)c(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C12 compound treatment 96800.0 -8210.0 -0.25 114880.0 -5840.0 -0.15 -0.2872 -0.9695 3552993 CHDI2_001105 O=C(N/N=C/c1ccc(OCC#C)cc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C13 compound treatment 166080.0 61100.0 1.89 143880.0 23200.0 0.6 1.7635 0.8881 3551980 CHDI2_001106 COc1ccc(Br)cc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C14 compound treatment 161520.0 56500.0 1.75 146720.0 26000.0 0.68 1.7158 0.9142 1919338 CHDI2_001107 COc1cc(/C=N/NC(=O)c2ccccc2O)c(cc1OC)[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C15 compound treatment 149760.0 44800.0 1.39 132640.0 11900.0 0.31 1.1994 0.8442 3552797 CHDI2_001108 COc1cc(OC)c(/C=N/NC(=O)c2ccccn2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C16 compound treatment 158320.0 53300.0 1.65 129200.0 8480.0 0.22 1.3238 0.7944 3552870 CHDI2_001109 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C17 compound treatment 174160.0 69200.0 2.14 124160.0 3440.0 0.09 1.5782 0.736 1922614 CHDI2_001110 Oc1ccccc1C(=O)N/N=C/c2cc3OCOc3cc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C18 compound treatment 172440.0 67400.0 2.09 119040.0 -1680.0 -0.04 1.4465 0.6922 3552261 CHDI2_001111 Oc1ccccc1C(=O)N/N=C/c2c(F)c(F)c(F)c(F)c2F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C19 compound treatment 176480.0 71500.0 2.21 144880.0 24200.0 0.63 2.0097 0.8731 3551985 CHDI2_001112 Oc1ccccc1C(=O)N/N=C/c2cccnc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C20 compound treatment 183960.0 79000.0 2.45 164240.0 43500.0 1.13 2.5293 0.9385 3552264 CHDI2_001113 Oc1ccccc1C(=O)N/N=C/CCC=C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C21 compound treatment 184400.0 79400.0 2.46 149440.0 28700.0 0.75 2.267 0.8819 3551989 CHDI2_001114 Oc1ccccc1C(=O)N/N=C/c2ccncc2Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C22 compound treatment 165320.0 60300.0 1.87 114120.0 -6600.0 -0.17 1.2001 0.6395 3552269 CHDI2_001115 CC(=C)[C@H]1CCC(=CC1)/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C23 mock treatment 182720.0 77700.0 2.41 182320.0 61600.0 1.6 2.8343 0.9803 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 C24 mock treatment 138840.0 33800.0 1.05 137880.0 17200.0 0.45 1.0564 0.9275 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D01 compound treatment 129880.0 24900.0 0.77 100320.0 -20400.0 -0.53 0.1701 0.1818 3552455 CHDI2_001116 Brc1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D02 compound treatment 10160.0 -94900.0 -2.94 7760.0 -113000.0 -2.94 -4.1535 -1.0 3213180 CHDI2_001117 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D03 compound treatment 116600.0 11600.0 0.36 105680.0 -15000.0 -0.39 -0.0224 -0.0422 3552459 CHDI2_001118 Oc1ccc(/C=N/NC(=O)c2ccccn2)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D04 compound treatment 11040.0 -94000.0 -2.91 8320.0 -112000.0 -2.92 -4.1239 -1.0 3213222 CHDI2_001119 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(Oc2ccccc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D05 compound treatment 123800.0 18800.0 0.58 102200.0 -18500.0 -0.48 0.0714 0.0945 3552463 CHDI2_001120 Oc1ccc(Br)c(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D06 compound treatment 93080.0 -11900.0 -0.37 85760.0 -35000.0 -0.91 -0.9037 -0.9215 3213182 CHDI2_001121 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D07 compound treatment 55000.0 -50000.0 -1.55 72480.0 -48200.0 -1.25 -1.982 -0.9945 3552467 CHDI2_001122 COc1cc(Br)cc(/C=N/NC(=O)c2ccccn2)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D08 compound treatment 120680.0 15700.0 0.49 121520.0 799.0 0.02 0.358 0.7367 3213220 CHDI2_001123 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D09 compound treatment 101360.0 -3650.0 -0.11 83680.0 -37000.0 -0.96 -0.7605 -0.7848 3552471 CHDI2_001124 COc1ccc(Br)c(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D10 compound treatment 38160.0 -66900.0 -2.07 22720.0 -98000.0 -2.55 -3.2652 -0.9948 3214336 CHDI2_001125 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D11 compound treatment 112960.0 7950.0 0.25 68880.0 -51800.0 -1.35 -0.7783 -0.5684 3552923 CHDI2_001126 Oc1c(I)cc(I)cc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D12 compound treatment 92360.0 -12700.0 -0.39 77880.0 -42800.0 -1.11 -1.0643 -0.9018 3214338 CHDI2_001127 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D13 compound treatment 111480.0 6470.0 0.2 127160.0 6440.0 0.17 0.2601 0.996 3552475 CHDI2_001128 COc1ccc(Br)cc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D14 compound treatment 58800.0 -46200.0 -1.43 27400.0 -93300.0 -2.42 -2.727 -0.9684 3214376 CHDI2_001129 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D15 compound treatment 83960.0 -21100.0 -0.65 84640.0 -36100.0 -0.94 -1.1241 -0.9843 3552927 CHDI2_001130 CN(C)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D16 compound treatment 59400.0 -45600.0 -1.41 38920.0 -81800.0 -2.13 -2.5022 -0.9803 3214946 CHDI2_001131 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D17 compound treatment 109040.0 4030.0 0.12 109280.0 -11400.0 -0.3 -0.1219 -0.3781 3552479 CHDI2_001132 Brc1cc2OCOc2cc1/C=N/NC(=O)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D18 compound treatment 84600.0 -20400.0 -0.63 43120.0 -77600.0 -2.02 -1.8729 -0.8863 3214988 CHDI2_001133 ONC(=O)CCCCC(=O)N/N=C/c1cccc(Oc2ccccc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D19 compound treatment 121320.0 16300.0 0.51 124360.0 3640.0 0.09 0.4242 0.8251 3552483 CHDI2_001134 Brc1ncccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D20 compound treatment 40480.0 -64500.0 -2.0 32040.0 -88700.0 -2.3 -3.0431 -0.9975 3553073 CHDI2_001135 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D21 compound treatment 129840.0 24800.0 0.77 108000.0 -12700.0 -0.33 0.3103 0.3706 3552486 CHDI2_001136 Brc1cnccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D22 compound treatment 64680.0 -40300.0 -1.25 53960.0 -66800.0 -1.73 -2.1102 -0.987 3553737 CHDI2_001137 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)ccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D23 mock treatment 143600.0 38600.0 1.2 127040.0 6320.0 0.16 0.9616 0.7967 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 D24 mock treatment 113360.0 8350.0 0.26 115480.0 -5240.0 -0.14 0.0866 0.2964 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E01 compound treatment 125880.0 20900.0 0.65 103320.0 -17400.0 -0.45 0.1375 0.1743 3552839 CHDI2_001138 COc1cc(/C=N/NC(=O)c2ccccn2)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E02 compound treatment 171840.0 66800.0 2.07 121120.0 399.0 0.01 1.4715 0.7106 3552874 CHDI2_001139 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E03 compound treatment 95640.0 -9370.0 -0.29 80600.0 -40100.0 -1.04 -0.9424 -0.8709 3551996 CHDI2_001140 Oc1ccccc1C(=O)N/N=C/c2ccc(Br)s2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E04 compound treatment 51720.0 -53300.0 -1.65 54600.0 -66100.0 -1.72 -2.3824 -0.9998 3552276 CHDI2_001141 Oc1ccccc1C(=O)N/N=C/c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E05 compound treatment 149360.0 44400.0 1.37 108280.0 -12400.0 -0.32 0.7431 0.5264 3552001 CHDI2_001142 COc1cc(/C=N/NC(=O)c2ccccc2O)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E06 compound treatment 81360.0 -23700.0 -0.73 64040.0 -56700.0 -1.47 -1.5595 -0.9481 3552280 CHDI2_001143 Oc1ccccc1C(=O)N/N=C/c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E07 compound treatment 28880.0 -76100.0 -2.36 25080.0 -95600.0 -2.49 -3.4251 -0.9997 3552005 CHDI2_001144 Oc1ccccc1C(=O)N/N=C/c2ccc(OCc3ccccc3)cc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E08 compound treatment 110960.0 5950.0 0.18 98880.0 -21800.0 -0.57 -0.2709 -0.454 1912699 CHDI2_001145 Oc1ccccc1C(=O)N/N=C/c2cccnc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E09 compound treatment 118920.0 13900.0 0.43 106920.0 -13800.0 -0.36 0.0512 0.0913 3552842 CHDI2_001146 CC(C)(C)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E10 compound treatment 121760.0 16800.0 0.52 130640.0 9920.0 0.26 0.5492 0.9478 3552878 CHDI2_001147 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E11 compound treatment 142360.0 37400.0 1.16 135280.0 14600.0 0.38 1.0858 0.8918 3552009 CHDI2_001148 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E12 compound treatment 119760.0 14800.0 0.46 104040.0 -16700.0 -0.43 0.0167 0.0265 3552285 CHDI2_001149 Cc1ncc(CO)c(/C=N/NC(=O)c2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E13 compound treatment 125840.0 20800.0 0.65 144600.0 23900.0 0.62 0.8951 0.9998 3552013 CHDI2_001150 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E14 compound treatment 136200.0 31200.0 0.97 148880.0 28200.0 0.73 1.2007 0.9906 1917465 CHDI2_001151 Oc1ccccc1C(=O)N/N=C/c2ccc[nH]2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E15 compound treatment 141200.0 36200.0 1.12 123760.0 3040.0 0.08 0.8487 0.755 3552017 CHDI2_001152 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E16 compound treatment 148600.0 43600.0 1.35 123360.0 2640.0 0.07 1.0035 0.742 3552291 CHDI2_001153 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)N3CCCC3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E17 compound treatment 145480.0 40500.0 1.25 108200.0 -12500.0 -0.33 0.6566 0.5069 3552846 CHDI2_001154 CC1=C(C/C=N/NC(=O)c2ccccn2)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E18 compound treatment 148400.0 43400.0 1.34 140200.0 19500.0 0.51 1.3085 0.9109 3552881 CHDI2_001155 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E19 compound treatment 128320.0 23300.0 0.72 136480.0 15800.0 0.41 0.8002 0.9639 3552021 CHDI2_001156 OC(=O)c1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E20 compound treatment 35280.0 -69700.0 -2.16 32480.0 -88200.0 -2.29 -3.149 -0.9996 2119509 CHDI2_001157 Oc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E21 compound treatment 168840.0 63800.0 1.98 138960.0 18200.0 0.47 1.7336 0.8524 3552026 CHDI2_001158 OC(=O)c1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E22 compound treatment 170640.0 65600.0 2.03 161040.0 40300.0 1.05 2.1787 0.9524 3552296 CHDI2_001159 CCCCCCC/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E23 mock treatment 123480.0 18500.0 0.57 140680.0 20000.0 0.52 0.7714 0.9988 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 E24 mock treatment 113080.0 8070.0 0.25 116120.0 -4600.0 -0.12 0.0923 0.3329 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F01 compound treatment 43640.0 -61400.0 -1.9 38640.0 -82100.0 -2.13 -2.8526 -0.9984 3552931 CHDI2_001160 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4ccccn4)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F02 compound treatment 108000.0 2990.0 0.09 94280.0 -26400.0 -0.69 -0.4203 -0.6063 3213256 CHDI2_001161 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(cc1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F03 compound treatment 113000.0 7990.0 0.25 106480.0 -14200.0 -0.37 -0.0866 -0.1945 3552494 CHDI2_001162 Brc1ccc(/C=N/NC(=O)c2ccccn2)s1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F04 compound treatment 44880.0 -60100.0 -1.86 43000.0 -77700.0 -2.02 -2.7454 -0.9992 3213294 CHDI2_001163 ONC(=O)CCCCCCC(=O)N/N=C/c1nccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F05 compound treatment 112160.0 7150.0 0.22 97840.0 -22900.0 -0.59 -0.2637 -0.4157 3552498 CHDI2_001164 COc1cc(/C=N/NC(=O)c2ccccn2)c(Br)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F06 compound treatment 115000.0 9990.0 0.31 96600.0 -24100.0 -0.63 -0.2243 -0.3209 3213258 CHDI2_001165 OC(=O)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F07 compound treatment 37200.0 -67800.0 -2.1 29120.0 -91600.0 -2.38 -3.1686 -0.9981 3552502 CHDI2_001166 Oc1cc(OCc2ccccc2)ccc1/C=N/NC(=O)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F08 compound treatment 101680.0 -3330.0 -0.1 102840.0 -17900.0 -0.46 -0.4015 -0.8436 3213292 CHDI2_001167 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2nccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F09 compound treatment 99640.0 -5370.0 -0.17 100800.0 -19900.0 -0.52 -0.4837 -0.8896 3552936 CHDI2_001168 Fc1cc(/C=N/NC(=O)c2ccccn2)ccc1c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F10 compound treatment 93960.0 -11100.0 -0.34 99640.0 -21100.0 -0.55 -0.6294 -0.9744 3214412 CHDI2_001169 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(cc1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F11 compound treatment 89640.0 -15400.0 -0.48 103840.0 -16900.0 -0.44 -0.6469 -0.9992 3552506 CHDI2_001170 CC(C)(C)OC(=O)NC1(CCCC1)/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F12 compound treatment 112120.0 7110.0 0.22 98440.0 -22300.0 -0.58 -0.2536 -0.4094 3214414 CHDI2_001171 OC(=O)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F13 compound treatment 93280.0 -11700.0 -0.36 102000.0 -18700.0 -0.49 -0.601 -0.9897 3552509 CHDI2_001172 CC(C)(C)OC(=O)N1CCC[C@H]1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F14 compound treatment 121040.0 16000.0 0.5 117320.0 -3400.0 -0.09 0.2887 0.5723 3214448 CHDI2_001173 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2nccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F15 compound treatment 120160.0 15200.0 0.47 117200.0 -3520.0 -0.09 0.2672 0.5588 3552513 CHDI2_001174 CC(C)(C)OC(=O)Nc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F16 compound treatment 120560.0 15600.0 0.48 113000.0 -7720.0 -0.2 0.1988 0.381 3215022 CHDI2_001175 ONC(=O)CCCCC(=O)N/N=C/c1ccc(cc1)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F17 compound treatment 108040.0 3030.0 0.09 108800.0 -11900.0 -0.31 -0.1526 -0.4716 3552940 CHDI2_001176 OS(=O)(=O)c1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F18 compound treatment 104800.0 -210.0 -0.01 111480.0 -9240.0 -0.24 -0.1744 -0.726 3215060 CHDI2_001177 ONC(=O)CCCCC(=O)N/N=C/c1nccs1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F19 compound treatment 129280.0 24300.0 0.75 116960.0 -3760.0 -0.1 0.4626 0.6101 3552517 CHDI2_001178 OC(=O)c1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F20 compound treatment 123440.0 18400.0 0.57 111040.0 -9680.0 -0.25 0.2259 0.3621 3553108 CHDI2_001179 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(cc2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F21 compound treatment 102720.0 -2290.0 -0.07 91560.0 -29200.0 -0.76 -0.5859 -0.77 3552521 CHDI2_001180 OC(=O)c1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F22 compound treatment 134840.0 29800.0 0.92 127320.0 6600.0 0.17 0.7748 0.8242 3553771 CHDI2_001181 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(cc2)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F23 mock treatment 120400.0 15400.0 0.48 131000.0 10300.0 0.27 0.526 0.9625 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 F24 mock treatment 111720.0 6710.0 0.21 106200.0 -14500.0 -0.38 -0.1198 -0.278 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G01 compound treatment 134240.0 29200.0 0.91 145840.0 25100.0 0.65 1.1019 0.9871 3552033 CHDI2_001182 Oc1ccccc1C(=O)N/N=C/c2ccccc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G02 compound treatment 137920.0 32900.0 1.02 117080.0 -3640.0 -0.09 0.6541 0.6388 1918398 CHDI2_001183 Oc1ccccc1C(=O)N/N=C/c2cccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G03 compound treatment 98120.0 -6890.0 -0.21 117560.0 -3160.0 -0.08 -0.209 -0.9139 3552850 CHDI2_001184 NC(=O)COc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G04 compound treatment 109600.0 4590.0 0.14 101520.0 -19200.0 -0.5 -0.2522 -0.4862 3552884 CHDI2_001185 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G05 compound treatment 95280.0 -9730.0 -0.3 105080.0 -15600.0 -0.41 -0.5005 -0.9892 3552037 CHDI2_001186 Oc1ccccc1C(=O)N/N=C/c2cccnc2Cl 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G06 compound treatment 113000.0 7990.0 0.25 91760.0 -29000.0 -0.75 -0.357 -0.4507 3552305 CHDI2_001187 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)C(F)(F)F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G07 compound treatment 50360.0 -54700.0 -1.69 51960.0 -68800.0 -1.79 -2.4607 -0.9996 3552041 CHDI2_001188 Oc1ccccc1C(=O)N/N=C/C=C/c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G08 compound treatment 27640.0 -77400.0 -2.4 16200.0 -105000.0 -2.72 -3.6155 -0.9981 3552309 CHDI2_001189 Oc1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G09 compound treatment 84960.0 -20100.0 -0.62 82720.0 -38000.0 -0.99 -1.1375 -0.9751 3552044 CHDI2_001190 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G10 compound treatment 26560.0 -78500.0 -2.43 23400.0 -97300.0 -2.53 -3.5068 -0.9998 3552313 CHDI2_001191 Oc1cc(O)c(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G11 compound treatment 95440.0 -9570.0 -0.3 85200.0 -35500.0 -0.92 -0.8623 -0.8895 3552048 CHDI2_001192 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G12 compound treatment 91320.0 -13700.0 -0.42 121800.0 1080.0 0.03 -0.2801 -0.6589 3552317 CHDI2_001193 COc1cc(OC)c(/C=N/NC(=O)c2ccccc2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G13 compound treatment 91280.0 -13700.0 -0.43 91720.0 -29000.0 -0.75 -0.8336 -0.9634 3552051 CHDI2_001194 Oc1ccccc1C(=O)N/N=C/c2ccc(C#N)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G14 compound treatment 113320.0 8310.0 0.26 114040.0 -6680.0 -0.17 0.0593 0.191 3552321 CHDI2_001195 COc1cc(/C=N/NC(=O)c2ccccc2O)cc(OC)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G15 compound treatment 103000.0 -2010.0 -0.06 113560.0 -7160.0 -0.19 -0.1756 -0.895 3552054 CHDI2_001196 Oc1ccccc1C(=O)N/N=C/C2CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G16 compound treatment 117200.0 12200.0 0.38 112200.0 -8520.0 -0.22 0.1105 0.2524 3552325 CHDI2_001197 CC(C)(C)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G17 compound treatment 119360.0 14400.0 0.44 106560.0 -14200.0 -0.37 0.0542 0.0939 3552058 CHDI2_001198 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G18 compound treatment 107560.0 2550.0 0.08 110360.0 -10400.0 -0.27 -0.1345 -0.4794 3552329 CHDI2_001199 CC1=C(C/C=N/NC(=O)c2ccccc2O)C(C)(C)CCC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G19 compound treatment 126200.0 21200.0 0.66 99840.0 -20900.0 -0.54 0.0806 0.0947 3552855 CHDI2_001200 NC(=O)COc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G20 compound treatment 123480.0 18500.0 0.57 103480.0 -17200.0 -0.45 0.0879 0.1209 3552885 CHDI2_001201 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G21 compound treatment 21480.0 -83500.0 -2.59 19200.0 -102000.0 -2.64 -3.6953 -1.0 3552062 CHDI2_001202 Oc1ccccc1C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G22 compound treatment 109040.0 4030.0 0.12 115040.0 -5680.0 -0.15 -0.0161 -0.0832 3552333 CHDI2_001203 NC(=O)COc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G23 mock treatment 108040.0 3030.0 0.09 123440.0 2720.0 0.07 0.1163 0.9902 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 G24 mock treatment 99720.0 -5290.0 -0.16 120560.0 -161.0 0.0 -0.1189 -0.7249 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H01 compound treatment 124640.0 19600.0 0.61 135800.0 15100.0 0.39 0.7071 0.9774 1936274 CHDI2_001204 Clc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H02 compound treatment 7160.0 -97900.0 -3.03 7840.0 -113000.0 -2.93 -4.2178 -0.9999 3213330 CHDI2_001205 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H03 compound treatment 106840.0 1830.0 0.06 117440.0 -3280.0 -0.09 -0.0202 -0.1972 3552944 CHDI2_001206 Cn1cc(/C=N/NC(=O)c2ccccn2)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H04 compound treatment 87280.0 -17700.0 -0.55 77880.0 -42800.0 -1.11 -1.1756 -0.947 3213372 CHDI2_001207 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H05 compound treatment 93800.0 -11200.0 -0.35 98120.0 -22600.0 -0.59 -0.6608 -0.9686 3552530 CHDI2_001208 Clc1ncccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H06 compound treatment 123000.0 18000.0 0.56 92040.0 -28700.0 -0.75 -0.1328 -0.1427 3213332 CHDI2_001209 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H07 compound treatment 95240.0 -9770.0 -0.3 90440.0 -30300.0 -0.79 -0.7704 -0.9139 3552534 CHDI2_001210 O=C(N/N=C/C=C/c1ccccc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H08 compound treatment 102320.0 -2690.0 -0.08 101600.0 -19100.0 -0.5 -0.4102 -0.8144 3213370 CHDI2_001211 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H09 compound treatment 91440.0 -13600.0 -0.42 89000.0 -31700.0 -0.82 -0.8801 -0.9512 3552538 CHDI2_001212 C[C@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H10 compound treatment 8120.0 -96900.0 -3.0 7560.0 -113000.0 -2.94 -4.2019 -0.9999 3214486 CHDI2_001213 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H11 compound treatment 90040.0 -15000.0 -0.46 96240.0 -24500.0 -0.64 -0.7778 -0.988 3552543 CHDI2_001214 C[C@@H](CCC=C(C)C)C/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H12 compound treatment 14880.0 -90100.0 -2.79 9480.0 -111000.0 -2.89 -4.0185 -0.9999 3214488 CHDI2_001215 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H13 compound treatment 80360.0 -24700.0 -0.76 86720.0 -34000.0 -0.88 -1.1648 -0.9974 3552545 CHDI2_001216 O=C(N/N=C/c1ccc(C#N)cc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H14 compound treatment 113760.0 8750.0 0.27 110520.0 -10200.0 -0.27 0.0043 0.0113 3214526 CHDI2_001217 NC(=O)COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H15 compound treatment 100240.0 -4770.0 -0.15 98080.0 -22600.0 -0.59 -0.5205 -0.8581 3552548 CHDI2_001218 O=C(N/N=C/C1CCCCC1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H16 compound treatment 63520.0 -41500.0 -1.29 36120.0 -84600.0 -2.2 -2.4634 -0.9674 3215096 CHDI2_001219 CCCCN(CCCC)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H17 compound treatment 128160.0 23200.0 0.72 114560.0 -6160.0 -0.16 0.394 0.5361 3552552 CHDI2_001220 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H18 compound treatment 106120.0 1110.0 0.03 101200.0 -19500.0 -0.51 -0.3343 -0.6576 3215138 CHDI2_001221 NC(=O)COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H19 compound treatment 105400.0 390.0 0.01 97360.0 -23400.0 -0.61 -0.4207 -0.6929 3552948 CHDI2_001222 O=C(N/N=C/c1cn(Cc2ccccc2)c3ccccc13)c4ccccn4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H20 compound treatment 26760.0 -78300.0 -2.42 10320.0 -110000.0 -2.87 -3.7428 -0.9965 3553145 CHDI2_001223 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H21 compound treatment 109320.0 4310.0 0.13 112080.0 -8640.0 -0.22 -0.0643 -0.2463 3552556 CHDI2_001224 Oc1c(Br)cc(Br)cc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H22 compound treatment 20880.0 -84100.0 -2.61 9280.0 -111000.0 -2.9 -3.8907 -0.9986 3553805 CHDI2_001225 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H23 mock treatment 123880.0 18900.0 0.58 110040.0 -10700.0 -0.28 0.2172 0.3356 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 H24 mock treatment 79880.0 -25100.0 -0.78 114600.0 -6120.0 -0.16 -0.663 -0.8343 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I01 compound treatment 89560.0 -15500.0 -0.48 100680.0 -20000.0 -0.52 -0.7067 -0.9991 3552070 CHDI2_001226 COc1cc(Cl)c(/C=N/NC(=O)c2ccccc2O)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I02 compound treatment 113160.0 8150.0 0.25 145680.0 25000.0 0.65 0.6371 0.9155 1918345 CHDI2_001227 Oc1ccccc1C(=O)NN=C2CCCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I03 compound treatment 20320.0 -84700.0 -2.62 26640.0 -94100.0 -2.44 -3.584 -0.9994 2082285 CHDI2_001228 Oc1ccccc1C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I04 compound treatment 102040.0 -2970.0 -0.09 121800.0 1080.0 0.03 -0.0452 -0.4704 3554225 CHDI2_001229 Oc1ccccc1C(=O)NN=C2CCCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I05 compound treatment 95240.0 -9770.0 -0.3 97840.0 -22900.0 -0.59 -0.6344 -0.951 3554230 CHDI2_001230 O=C(NN=C1CCCCCCC1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I06 compound treatment 70840.0 -34200.0 -1.06 87400.0 -33300.0 -0.87 -1.3608 -0.995 3552890 CHDI2_001231 O=C(N/N=C/c1ccc(Oc2ccccc2)cc1)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I07 compound treatment 25280.0 -79700.0 -2.47 24520.0 -96200.0 -2.5 -3.5143 -1.0 3552075 CHDI2_001232 Oc1ccccc1C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I08 compound treatment 98000.0 -7010.0 -0.22 91880.0 -28800.0 -0.75 -0.6835 -0.876 3552414 CHDI2_001233 Oc1ccccc1C(=O)N/N=C/Cc2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I09 compound treatment 15240.0 -89800.0 -2.78 13280.0 -107000.0 -2.79 -3.9408 -1.0 3552079 CHDI2_001234 CCN(CC)c1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I10 compound treatment 94320.0 -10700.0 -0.33 95280.0 -25400.0 -0.66 -0.7016 -0.949 3552416 CHDI2_001235 COC(=O)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I11 compound treatment 102240.0 -2770.0 -0.09 84800.0 -35900.0 -0.93 -0.7207 -0.7689 3552083 CHDI2_001236 Oc1ccccc1C(=O)N/N=C/c2ccc3OCCc3c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I12 compound treatment 107360.0 2350.0 0.07 109480.0 -11200.0 -0.29 -0.155 -0.5151 3552341 CHDI2_001237 COc1cc(Br)c(/C=N/NC(=O)c2ccccc2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I13 compound treatment 39200.0 -65800.0 -2.04 32680.0 -88000.0 -2.29 -3.0594 -0.9984 3552087 CHDI2_001238 Oc1cccc(/C=N/NC(=O)c2ccccc2O)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I14 compound treatment 91600.0 -13400.0 -0.42 89200.0 -31500.0 -0.82 -0.8729 -0.9505 3552418 CHDI2_001239 Oc1ccccc1C(=O)N/N=C/c2cc3ccccc3n2S(=O)(=O)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I15 compound treatment 31680.0 -73300.0 -2.27 27240.0 -93500.0 -2.43 -3.3241 -0.9994 3552091 CHDI2_001240 Oc1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I16 compound treatment 65680.0 -39300.0 -1.22 83880.0 -36800.0 -0.96 -1.5386 -0.9929 3552345 CHDI2_001241 Oc1ccccc1C(=O)N/N=C/c2ccc(cc2)N(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I17 compound treatment 84320.0 -20700.0 -0.64 87600.0 -33100.0 -0.86 -1.0618 -0.9895 3552095 CHDI2_001242 Oc1ccc(O)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I18 compound treatment 90520.0 -14500.0 -0.45 95560.0 -25200.0 -0.65 -0.7797 -0.9832 3552349 CHDI2_001243 Oc1ccccc1C(=O)N/N=C/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I19 compound treatment 100800.0 -4210.0 -0.13 106400.0 -14300.0 -0.37 -0.3554 -0.9012 3552098 CHDI2_001244 Oc1ccc(/C=N/NC(=O)c2ccccc2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I20 compound treatment 116200.0 11200.0 0.35 104840.0 -15900.0 -0.41 -0.0466 -0.0865 3552420 CHDI2_001245 OB(O)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I21 compound treatment 100000.0 -5010.0 -0.16 101640.0 -19100.0 -0.5 -0.4603 -0.8861 3554228 CHDI2_001246 O=C(NN=C1CCCCCC1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I22 compound treatment 86280.0 -18700.0 -0.58 73600.0 -47100.0 -1.22 -1.2761 -0.9418 3552894 CHDI2_001247 [O-][n+]1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I23 mock treatment 111080.0 6070.0 0.19 124040.0 3320.0 0.09 0.194 0.9375 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 I24 mock treatment 77520.0 -27500.0 -0.85 111280.0 -9440.0 -0.25 -0.7757 -0.8752 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J01 compound treatment 90520.0 -14500.0 -0.45 134840.0 14100.0 0.37 -0.0581 -0.1002 3552565 CHDI2_001248 COc1cc(Cl)c(/C=N/NC(=O)c2ccccn2)c(Cl)c1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J02 compound treatment 45080.0 -59900.0 -1.86 56520.0 -64200.0 -1.67 -2.4926 -0.9986 3213410 CHDI2_001249 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J03 compound treatment 61080.0 -43900.0 -1.36 45000.0 -75700.0 -1.97 -2.3537 -0.9838 3552569 CHDI2_001250 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J04 mock treatment 111560.0 6550.0 0.2 112600.0 -8120.0 -0.21 -0.0057 -0.0195 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J05 compound treatment 98440.0 -6570.0 -0.2 95760.0 -25000.0 -0.65 -0.6025 -0.8864 3552951 CHDI2_001251 O=C(N/N=C/C1=CCCCC1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J06 compound treatment 99920.0 -5090.0 -0.16 101200.0 -19500.0 -0.51 -0.4702 -0.8852 3213412 CHDI2_001252 COc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J07 compound treatment 90720.0 -14300.0 -0.44 102320.0 -18400.0 -0.48 -0.6512 -0.9993 3552573 CHDI2_001253 Oc1c(/C=N/NC(=O)c2ccccn2)cc(Br)cc1[N+](=O)[O-] 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J08 mock treatment 94960.0 -10100.0 -0.31 81400.0 -39300.0 -1.02 -0.9426 -0.8825 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J09 compound treatment 15560.0 -89500.0 -2.77 17400.0 -103000.0 -2.68 -3.8581 -0.9999 3552578 CHDI2_001254 CCN(CC)c1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J10 compound treatment 78280.0 -26700.0 -0.83 76200.0 -44500.0 -1.16 -1.4036 -0.9866 3214566 CHDI2_001255 COc1ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J11 compound treatment 99280.0 -5730.0 -0.18 84320.0 -36400.0 -0.95 -0.7943 -0.8254 3552582 CHDI2_001256 O=C(N/N=C/c1ccc2OCCc2c1)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J12 compound treatment 102480.0 -2530.0 -0.08 107720.0 -13000.0 -0.34 -0.2943 -0.8486 3214568 CHDI2_001257 COc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J13 compound treatment 33640.0 -71400.0 -2.21 32400.0 -88300.0 -2.29 -3.1864 -0.9998 3552586 CHDI2_001258 Oc1cccc(/C=N/NC(=O)c2ccccn2)c1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J14 compound treatment 90200.0 -14800.0 -0.46 87960.0 -32800.0 -0.85 -0.9264 -0.958 3214215 CHDI2_001259 NNC(=O)CCCCCC(=O)Nc1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J15 compound treatment 35360.0 -69700.0 -2.16 37520.0 -83200.0 -2.16 -3.0546 -1.0 3552590 CHDI2_001260 Oc1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J16 compound treatment 87360.0 -17700.0 -0.55 99240.0 -21500.0 -0.56 -0.7814 -0.9999 3215176 CHDI2_001261 COc1ccc(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J17 compound treatment 96600.0 -8410.0 -0.26 107960.0 -12800.0 -0.33 -0.4187 -0.9929 3552594 CHDI2_001262 Oc1ccc(O)c(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J18 compound treatment 100280.0 -4730.0 -0.15 106400.0 -14300.0 -0.37 -0.3667 -0.917 3214824 CHDI2_001263 NNC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J19 compound treatment 88440.0 -16600.0 -0.51 89520.0 -31200.0 -0.81 -0.9363 -0.9757 1936679 CHDI2_001264 Oc1ccc(/C=N/NC(=O)c2ccccn2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J20 compound treatment 96040.0 -8970.0 -0.28 104040.0 -16700.0 -0.43 -0.503 -0.9769 3553235 CHDI2_001265 COc1ccc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J21 compound treatment 104000.0 -1010.0 -0.03 110520.0 -10200.0 -0.27 -0.2096 -0.7851 3552955 CHDI2_001266 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J22 compound treatment 92760.0 -12300.0 -0.38 95880.0 -24800.0 -0.65 -0.7248 -0.968 3553843 CHDI2_001267 COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J23 mock treatment 114560.0 9550.0 0.3 119040.0 -1680.0 -0.04 0.1783 0.5963 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 J24 mock treatment 87520.0 -17500.0 -0.54 108480.0 -12200.0 -0.32 -0.6081 -0.9678 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K01 compound treatment 63720.0 -41300.0 -1.28 139920.0 19200.0 0.5 -0.5519 -0.4019 3552103 CHDI2_001268 COc1cccc(OC)c1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K02 compound treatment 97160.0 -7850.0 -0.24 144800.0 24100.0 0.63 0.2704 0.4028 3552353 CHDI2_001269 OC[C@@H](O)[C@@H](O)[C@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K03 compound treatment 100360.0 -4650.0 -0.14 136680.0 16000.0 0.41 0.1913 0.4359 1913656 CHDI2_001270 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K04 compound treatment 107360.0 2350.0 0.07 101840.0 -18900.0 -0.49 -0.2954 -0.5956 3552357 CHDI2_001271 C[C@@H](O)[C@@H](O)[C@@H](O)C/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K05 compound treatment 91920.0 -13100.0 -0.41 107000.0 -13700.0 -0.36 -0.5389 -0.9979 3552108 CHDI2_001272 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K06 compound treatment 100440.0 -4570.0 -0.14 93320.0 -27400.0 -0.71 -0.6036 -0.8315 3552361 CHDI2_001273 OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K07 compound treatment 91640.0 -13400.0 -0.41 85160.0 -35600.0 -0.92 -0.9463 -0.9345 3552977 CHDI2_001274 O=C(N/N=C/Cc1ccccc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K08 compound treatment 73040.0 -32000.0 -0.99 91600.0 -29100.0 -0.76 -1.2355 -0.9912 3552898 CHDI2_001275 O=C(N/N=C/c1ccc2ccccc2n1)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K09 compound treatment 106880.0 1870.0 0.06 101440.0 -19300.0 -0.5 -0.3133 -0.6212 3552111 CHDI2_001276 CC1(C)COC(CCC/C=N/NC(=O)c2ccccc2O)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K10 compound treatment 96320.0 -8690.0 -0.27 103800.0 -16900.0 -0.44 -0.5013 -0.9723 3552365 CHDI2_001277 OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K11 compound treatment 97600.0 -7410.0 -0.23 105800.0 -14900.0 -0.39 -0.4365 -0.9687 3552115 CHDI2_001278 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3ccccc3O)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K12 compound treatment 86480.0 -18500.0 -0.57 93720.0 -27000.0 -0.7 -0.9021 -0.995 3552366 CHDI2_001279 OC[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K13 compound treatment 77400.0 -27600.0 -0.86 86920.0 -33800.0 -0.88 -1.2259 -0.9999 3552118 CHDI2_001280 Oc1ccccc1C(=O)N/N=C/c2cc(Br)cs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K14 compound treatment 96320.0 -8690.0 -0.27 103400.0 -17300.0 -0.45 -0.5086 -0.9698 3552369 CHDI2_001281 C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K15 compound treatment 90280.0 -14700.0 -0.46 92760.0 -28000.0 -0.73 -0.8364 -0.9749 3552981 CHDI2_001282 COC(=O)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K16 compound treatment 88000.0 -17000.0 -0.53 92640.0 -28100.0 -0.73 -0.8886 -0.9873 3552902 CHDI2_001283 Cc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K17 compound treatment 99080.0 -5930.0 -0.18 103720.0 -17000.0 -0.44 -0.4423 -0.9244 3552121 CHDI2_001284 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K18 compound treatment 66640.0 -38400.0 -1.19 71040.0 -49700.0 -1.29 -1.7534 -0.9992 3552373 CHDI2_001285 Oc1ccccc1C(=O)N/N=C/c2ccc(Oc3ccccc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K19 compound treatment 100560.0 -4450.0 -0.14 105640.0 -15100.0 -0.39 -0.3746 -0.9017 3552125 CHDI2_001286 Oc1ccccc1C(=O)N/N=C/c2ccc-3c(Cc4ccccc43)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K20 compound treatment 89560.0 -15500.0 -0.48 105640.0 -15100.0 -0.39 -0.6156 -0.9951 3552377 CHDI2_001287 Oc1ccccc1C(=O)N/N=C/c2cc[n+]([O-])cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K21 compound treatment 112040.0 7030.0 0.22 109760.0 -11000.0 -0.28 -0.0474 -0.1321 1922658 CHDI2_001288 Oc1ccccc1C(=O)N/N=C/c2ccc(F)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K22 compound treatment 102400.0 -2610.0 -0.08 100920.0 -19800.0 -0.51 -0.421 -0.8083 3552381 CHDI2_001289 Oc1ccccc1C(=O)N/N=C/c2ccc3ccccc3n2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K23 mock treatment 107400.0 2390.0 0.07 115160.0 -5560.0 -0.14 -0.0498 -0.3068 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 K24 mock treatment 84360.0 -20700.0 -0.64 136920.0 16200.0 0.42 -0.1548 -0.2021 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L01 compound treatment 65840.0 -39200.0 -1.21 105680.0 -15000.0 -0.39 -1.1345 -0.8898 3552603 CHDI2_001290 COc1cccc(OC)c1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L02 compound treatment 47400.0 -57600.0 -1.79 59160.0 -61600.0 -1.6 -2.3932 -0.9985 3214346 CHDI2_001291 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L03 compound treatment 92040.0 -13000.0 -0.4 130360.0 9640.0 0.25 -0.1071 -0.2261 3552607 CHDI2_001292 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L04 compound treatment 82080.0 -22900.0 -0.71 97320.0 -23400.0 -0.61 -0.9323 -0.997 3214446 CHDI2_001293 CCCCCCC/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L05 compound treatment 100040.0 -4970.0 -0.15 100160.0 -20600.0 -0.53 -0.4867 -0.8753 3552611 CHDI2_001294 COc1cc(O)cc(OC)c1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L06 compound treatment 25520.0 -79500.0 -2.46 25560.0 -95200.0 -2.47 -3.4899 -1.0 3214578 CHDI2_001295 COc1cc(Br)c(/C=N/NC(=O)CCCCCC(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L07 compound treatment 85360.0 -19700.0 -0.61 88200.0 -32500.0 -0.84 -1.028 -0.9871 3552957 CHDI2_001296 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L08 compound treatment 82040.0 -23000.0 -0.71 87240.0 -33500.0 -0.87 -1.1184 -0.995 3214706 CHDI2_001297 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L09 compound treatment 85920.0 -19100.0 -0.59 96440.0 -24300.0 -0.63 -0.8644 -0.9995 3552614 CHDI2_001298 CC1(C)COC(CCC/C=N/NC(=O)c2ccccn2)OC1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L10 compound treatment 87040.0 -18000.0 -0.56 92040.0 -28700.0 -0.75 -0.9207 -0.9897 3214810 CHDI2_001299 C/C(=N\NC(=O)CCCCCC(=O)NO)/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L11 compound treatment 89000.0 -16000.0 -0.5 88760.0 -32000.0 -0.83 -0.938 -0.9697 3552618 CHDI2_001300 Cc1nnc(Sc2ccc(/C=N/NC(=O)c3ccccn3)o2)n1C 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L12 compound treatment 101440.0 -3570.0 -0.11 111360.0 -9360.0 -0.24 -0.2502 -0.9364 3553399 CHDI2_001301 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3cccc(c3)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L13 compound treatment 83200.0 -21800.0 -0.68 90200.0 -30500.0 -0.79 -1.0386 -0.9968 3552622 CHDI2_001302 Brc1csc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L14 compound treatment 96920.0 -8090.0 -0.25 87040.0 -33700.0 -0.88 -0.7961 -0.8745 3553462 CHDI2_001303 CCCCCCC/C=N/NC(=O)c1cccc(c1)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L15 compound treatment 89200.0 -15800.0 -0.49 91040.0 -29700.0 -0.77 -0.8917 -0.976 3552961 CHDI2_001304 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccn2)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L16 compound treatment 94080.0 -10900.0 -0.34 101240.0 -19500.0 -0.51 -0.5974 -0.9809 3553506 CHDI2_001305 COc1cc(Br)c(/C=N/NC(=O)c2cccc(c2)C(=O)NO)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L17 compound treatment 94280.0 -10700.0 -0.33 89960.0 -30800.0 -0.8 -0.8003 -0.9244 3552626 CHDI2_001306 CC(C)(C)OC(=O)NC/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L18 compound treatment 94320.0 -10700.0 -0.33 93880.0 -26800.0 -0.7 -0.7274 -0.9421 3553553 CHDI2_001307 COc1cc(/C=N/NC(=O)c2cccc(c2)C(=O)NO)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L19 compound treatment 98560.0 -6450.0 -0.2 107080.0 -13600.0 -0.35 -0.3919 -0.9632 3552630 CHDI2_001308 O=C(N/N=C/c1ccc-2c(Cc3ccccc32)c1)c4ccccn4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L20 compound treatment 93880.0 -11100.0 -0.34 100600.0 -20100.0 -0.52 -0.6135 -0.9796 3554247 CHDI2_001309 C/C(=N\NC(=O)c1cccc(c1)C(=O)NO)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L21 compound treatment 87480.0 -17500.0 -0.54 90520.0 -30200.0 -0.78 -0.9389 -0.9839 3552634 CHDI2_001310 Fc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L22 compound treatment 103200.0 -1810.0 -0.06 122280.0 1560.0 0.04 -0.011 -0.1592 3552755 CHDI2_001311 CC1(C)[C@@H]2C[C@H]1C(=CC2)/C=N/NC(=O)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L23 mock treatment 100320.0 -4690.0 -0.15 116600.0 -4120.0 -0.11 -0.1785 -0.9887 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 L24 mock treatment 99720.0 -5290.0 -0.16 130520.0 9800.0 0.25 0.0641 0.2118 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M01 compound treatment 73280.0 -31700.0 -0.98 131040.0 10300.0 0.27 -0.5056 -0.4962 3552129 CHDI2_001312 Oc1ccc(/C=N/NC(=O)c2ccccc2O)cc1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M02 compound treatment 109640.0 4630.0 0.14 118880.0 -1840.0 -0.05 0.0676 0.4471 3552383 CHDI2_001313 Cc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M03 compound treatment 20960.0 -84100.0 -2.6 28920.0 -91800.0 -2.39 -3.5281 -0.999 3552133 CHDI2_001314 Oc1ccccc1C(=O)N/N=C/c2ccc(F)c(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M04 compound treatment 102560.0 -2450.0 -0.08 118480.0 -2240.0 -0.06 -0.0949 -0.9914 3552385 CHDI2_001315 COc1cc(/C=N/NC(=O)c2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M05 compound treatment 28760.0 -76300.0 -2.36 28200.0 -92500.0 -2.4 -3.3704 -1.0 3552138 CHDI2_001316 Oc1ccc(F)cc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M06 compound treatment 96600.0 -8410.0 -0.26 115200.0 -5520.0 -0.14 -0.2857 -0.9605 3552386 CHDI2_001317 O[C@@H](/C=N/NC(=O)c1ccccc1O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M07 compound treatment 20720.0 -84300.0 -2.61 21760.0 -99000.0 -2.57 -3.6649 -1.0 3552142 CHDI2_001318 Oc1ccccc1C(=O)N/N=C/c2coc3ccccc3c2=O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M08 compound treatment 97920.0 -7090.0 -0.22 108440.0 -12300.0 -0.32 -0.381 -0.9834 3552388 CHDI2_001319 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M09 compound treatment 89200.0 -15800.0 -0.49 116880.0 -3840.0 -0.1 -0.417 -0.834 3552985 CHDI2_001320 O=C(N/N=C/c1cc2ccccc2n1S(=O)(=O)c3ccccc3)c4ccccn4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M10 compound treatment 103120.0 -1890.0 -0.06 94920.0 -25800.0 -0.67 -0.5154 -0.766 3552910 CHDI2_001321 O[C@@H](/C=N/NC(=O)c1ccccn1)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M11 compound treatment 89000.0 -16000.0 -0.5 111400.0 -9320.0 -0.24 -0.522 -0.9456 3552146 CHDI2_001322 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M12 compound treatment 102800.0 -2210.0 -0.07 98200.0 -22500.0 -0.59 -0.4622 -0.7845 1919426 CHDI2_001323 COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M13 compound treatment 102720.0 -2290.0 -0.07 110360.0 -10400.0 -0.27 -0.2405 -0.864 3552862 CHDI2_001324 O=C(N/N=C/c1ccc(cc1)N(c2ccccc2)c3ccccc3)c4ccccn4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M14 compound treatment 89600.0 -15400.0 -0.48 95520.0 -25200.0 -0.65 -0.8006 -0.988 3552913 CHDI2_001325 OC[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M15 compound treatment 90160.0 -14900.0 -0.46 105520.0 -15200.0 -0.39 -0.6046 -0.9971 3552150 CHDI2_001326 OB(O)c1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M16 compound treatment 84200.0 -20800.0 -0.64 117920.0 -2800.0 -0.07 -0.5074 -0.782 3552389 CHDI2_001327 CCOc1cccc(/C=N/NC(=O)c2ccccc2O)c1OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M17 compound treatment 91920.0 -13100.0 -0.41 117080.0 -3640.0 -0.09 -0.3537 -0.8492 1913661 CHDI2_001328 Oc1ccccc1C(=O)N/N=C/c2ccco2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M18 compound treatment 74240.0 -30800.0 -0.95 92960.0 -27800.0 -0.72 -1.1842 -0.9905 3552391 CHDI2_001329 Oc1ccccc1C(=O)N/N=C/c2cc(I)cc(I)c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M19 compound treatment 99560.0 -5450.0 -0.17 118560.0 -2160.0 -0.06 -0.1591 -0.8941 3552154 CHDI2_001330 Oc1ccccc1C(=O)N/N=C/c2ccoc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M20 compound treatment 96720.0 -8290.0 -0.26 96840.0 -23900.0 -0.62 -0.6204 -0.9238 1912672 CHDI2_001331 CN(C)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M21 compound treatment 100800.0 -4210.0 -0.13 97960.0 -22800.0 -0.59 -0.5104 -0.8428 3552158 CHDI2_001332 Oc1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M22 compound treatment 78760.0 -26300.0 -0.81 75920.0 -44800.0 -1.16 -1.3982 -0.9846 1919995 CHDI2_001333 CCn1c2ccccc2c3cc(/C=N/NC(=O)c4ccccc4O)ccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M23 mock treatment 96640.0 -8370.0 -0.26 135080.0 14400.0 0.37 0.0804 0.177 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 M24 mock treatment 99840.0 -5170.0 -0.16 122000.0 1280.0 0.03 -0.0898 -0.5488 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N01 compound treatment 42000.0 -63000.0 -1.95 62000.0 -58700.0 -1.53 -2.4594 -0.9926 3552638 CHDI2_001334 Oc1ccc(/C=N/NC(=O)c2ccccn2)cc1F 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N02 compound treatment 39440.0 -65600.0 -2.03 83560.0 -37200.0 -0.97 -2.1193 -0.9422 3213540 CHDI2_001335 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N03 compound treatment 84520.0 -20500.0 -0.63 126960.0 6240.0 0.16 -0.3343 -0.5102 3552642 CHDI2_001336 Fc1ccc(/C=N/NC(=O)c2ccccn2)cc1Oc3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N04 compound treatment 6000.0 -99000.0 -3.07 8720.0 -112000.0 -2.91 -4.227 -0.9997 3213580 CHDI2_001337 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(c(F)c1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N05 compound treatment 95520.0 -9490.0 -0.29 81360.0 -39400.0 -1.02 -0.9311 -0.875 3552646 CHDI2_001338 Oc1ccc(F)cc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N06 compound treatment 79360.0 -25700.0 -0.79 88840.0 -31900.0 -0.83 -1.1477 -0.9998 3213542 CHDI2_001339 Oc1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N07 compound treatment 79920.0 -25100.0 -0.78 97000.0 -23700.0 -0.62 -0.9855 -0.9934 3552650 CHDI2_001340 O=C(N/N=C/c1coc2ccccc2c1=O)c3ccccn3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N08 compound treatment 85560.0 -19500.0 -0.6 83840.0 -36900.0 -0.96 -1.1037 -0.975 3213578 CHDI2_001341 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N09 compound treatment 80600.0 -24400.0 -0.76 92800.0 -27900.0 -0.73 -1.0478 -0.9998 3552965 CHDI2_001342 CN(C)CCCOc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N10 compound treatment 67000.0 -38000.0 -1.18 84240.0 -36500.0 -0.95 -1.503 -0.9942 3214696 CHDI2_001343 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N11 compound treatment 82600.0 -22400.0 -0.69 106200.0 -14500.0 -0.38 -0.7578 -0.9589 3552654 CHDI2_001344 CC(C)(C)OC(=O)Nc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N12 compound treatment 88680.0 -16300.0 -0.51 90120.0 -30600.0 -0.8 -0.92 -0.9762 3214698 CHDI2_001345 Oc1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N13 compound treatment 98280.0 -6730.0 -0.21 101560.0 -19200.0 -0.5 -0.4995 -0.9254 3552969 CHDI2_001346 CCOc1cc(/C=N/NC(=O)c2ccccn2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N14 compound treatment 15760.0 -89300.0 -2.77 10880.0 -110000.0 -2.85 -3.9735 -0.9999 3214734 CHDI2_001347 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N15 compound treatment 78280.0 -26700.0 -0.83 72200.0 -48500.0 -1.26 -1.4771 -0.9792 3552658 CHDI2_001348 OB(O)c1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N16 compound treatment 72960.0 -32100.0 -0.99 94000.0 -26700.0 -0.69 -1.1931 -0.9847 3215306 CHDI2_001349 ONC(=O)CCCCC(=O)N/N=C/c1ccc(O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N17 compound treatment 96360.0 -8650.0 -0.27 91480.0 -29200.0 -0.76 -0.7268 -0.9021 1937927 CHDI2_001350 O=C(N/N=C/c1ccco1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N18 compound treatment 27240.0 -77800.0 -2.41 32840.0 -87900.0 -2.28 -3.3185 -0.9996 3215346 CHDI2_001351 ONC(=O)CCCCC(=O)N/N=C/c1ccc(c(F)c1)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N19 compound treatment 96040.0 -8970.0 -0.28 93160.0 -27600.0 -0.72 -0.7029 -0.915 3552663 CHDI2_001352 O=C(N/N=C/c1ccoc1)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N20 compound treatment 93240.0 -11800.0 -0.36 88320.0 -32400.0 -0.84 -0.8532 -0.9299 3553309 CHDI2_001353 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N21 compound treatment 75200.0 -29800.0 -0.92 76240.0 -44500.0 -1.16 -1.4704 -0.9938 3552665 CHDI2_001354 Oc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N22 compound treatment 74840.0 -30200.0 -0.93 102480.0 -18200.0 -0.47 -0.9961 -0.9504 3553913 CHDI2_001355 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N23 mock treatment 109080.0 4070.0 0.13 124360.0 3640.0 0.09 0.156 0.9899 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 N24 mock treatment 102320.0 -2690.0 -0.08 121920.0 1200.0 0.03 -0.0369 -0.4148 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O01 compound treatment 78280.0 -26700.0 -0.83 122760.0 2040.0 0.05 -0.5482 -0.6605 3552163 CHDI2_001356 OCCOc1ccccc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O02 compound treatment 122240.0 17200.0 0.53 151480.0 30800.0 0.8 0.9426 0.9808 3552395 CHDI2_001357 Oc1ccccc1C(=O)N/N=C/c2ccc(o2)S(=O)(=O)O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O03 compound treatment 88640.0 -16400.0 -0.51 147280.0 26600.0 0.69 0.1293 0.151 3552167 CHDI2_001358 OCCOc1cccc(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O04 compound treatment 84000.0 -21000.0 -0.65 129960.0 9240.0 0.24 -0.2906 -0.4188 3552397 CHDI2_001359 Cn1cc(/C=N/NC(=O)c2ccccc2O)c3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O05 compound treatment 81960.0 -23100.0 -0.71 124000.0 3280.0 0.09 -0.4448 -0.6184 3552171 CHDI2_001360 OCCOc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O06 compound treatment 34760.0 -70300.0 -2.18 52640.0 -68100.0 -1.77 -2.79 -0.9947 3552399 CHDI2_001361 Oc1ccccc1C(=O)N/N=C/c2cn(Cc3ccccc3)c4ccccc24 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O07 compound treatment 13040.0 -92000.0 -2.85 15000.0 -106000.0 -2.75 -3.9574 -0.9998 3552175 CHDI2_001362 COc1ccc(/C=N/NC(=O)c2ccccc2O)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O08 compound treatment 75720.0 -29300.0 -0.91 98040.0 -22700.0 -0.59 -1.0584 -0.9781 3552401 CHDI2_001363 Oc1ccccc1C(=O)N/N=C/C2=CCCCC2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O09 compound treatment 22200.0 -82800.0 -2.57 16200.0 -105000.0 -2.72 -3.7346 -0.9996 3552179 CHDI2_001364 COc1ccc(O)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O10 compound treatment 85760.0 -19300.0 -0.6 97480.0 -23200.0 -0.6 -0.8488 -1.0 3552403 CHDI2_001365 OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)/C=N/NC(=O)c1ccccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O11 compound treatment 83080.0 -21900.0 -0.68 90440.0 -30300.0 -0.79 -1.0368 -0.9973 3552866 CHDI2_001366 O=C(N/N=C/C[P+](c1ccccc1)(c2ccccc2)c3ccccc3)c4ccccn4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O12 compound treatment 76080.0 -28900.0 -0.9 73040.0 -47700.0 -1.24 -1.5099 -0.9874 3552915 CHDI2_001367 COc1ccc(/C=N/NC(=O)c2ccccn2)cc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O13 compound treatment 80640.0 -24400.0 -0.76 76760.0 -44000.0 -1.14 -1.3416 -0.9798 3552184 CHDI2_001368 COc1cc(/C=C/C=N/NC(=O)c2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O14 compound treatment 85440.0 -19600.0 -0.61 96280.0 -24400.0 -0.64 -0.8778 -0.9997 3552404 CHDI2_001369 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O15 compound treatment 48480.0 -56500.0 -1.75 27840.0 -92900.0 -2.41 -2.945 -0.9876 3552188 CHDI2_001370 Cc1ccc(O)c(/C=N/NC(=O)c2ccccc2O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O16 compound treatment 86480.0 -18500.0 -0.57 88840.0 -31900.0 -0.83 -0.9917 -0.984 3552406 CHDI2_001371 OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)/C=N/NC(=O)c2ccccc2O)[C@H](O)[C@@H](O)[C@H]1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O17 compound treatment 84000.0 -21000.0 -0.65 89080.0 -31600.0 -0.82 -1.0416 -0.9933 3552191 CHDI2_001372 OCc1ccc(/C=N/NC(=O)c2ccccc2O)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O18 compound treatment 62640.0 -42400.0 -1.31 101200.0 -19500.0 -0.51 -1.287 -0.9144 3554239 CHDI2_001373 C/C(=N\NC(=O)c1ccccc1O)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O19 compound treatment 8280.0 -96700.0 -3.0 8360.0 -112000.0 -2.92 -4.1837 -0.9999 3552195 CHDI2_001374 Oc1ccccc1C(=O)N/N=C/c2ccc3ccccc3c2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O20 compound treatment 75280.0 -29700.0 -0.92 95920.0 -24800.0 -0.64 -1.107 -0.9847 3552408 CHDI2_001375 CN(C)CCCOc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O21 compound treatment 11280.0 -93700.0 -2.9 41800.0 -78900.0 -2.05 -3.5036 -0.9855 3552199 CHDI2_001376 Oc1ccccc1C(=O)N/N=C/c2ccc(o2)c3cccc(Cl)c3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O22 compound treatment 95240.0 -9770.0 -0.3 123400.0 2680.0 0.07 -0.1648 -0.5307 3552410 CHDI2_001377 CCOc1cc(/C=N/NC(=O)c2ccccc2O)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O23 mock treatment 99040.0 -5970.0 -0.18 139080.0 18400.0 0.48 0.2065 0.4036 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 O24 mock treatment 109480.0 4470.0 0.14 121680.0 959.0 0.02 0.1156 0.8211 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P01 compound treatment 68360.0 -36700.0 -1.14 63840.0 -56900.0 -1.48 -1.848 -0.9915 3552673 CHDI2_001378 OCCOc1ccccc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P02 compound treatment 65960.0 -39100.0 -1.21 85160.0 -35600.0 -0.92 -1.5089 -0.9911 3213622 CHDI2_001379 ONC(=O)CCCCCCC(=O)N/N=C/c1cc(Br)c(O)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P03 compound treatment 42760.0 -62300.0 -1.93 88680.0 -32000.0 -0.83 -1.9525 -0.9294 3552677 CHDI2_001380 OCCOc1cccc(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P04 compound treatment 39760.0 -65300.0 -2.02 55840.0 -64900.0 -1.69 -2.6216 -0.9959 3213666 CHDI2_001381 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P05 compound treatment 61720.0 -43300.0 -1.34 97600.0 -23100.0 -0.6 -1.3733 -0.9344 3552680 CHDI2_001382 OCCOc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P06 compound treatment 64160.0 -40900.0 -1.27 90840.0 -29900.0 -0.78 -1.444 -0.9725 3213624 CHDI2_001383 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P07 compound treatment 32360.0 -72700.0 -2.25 43320.0 -77400.0 -2.01 -3.0138 -0.9984 3552684 CHDI2_001384 COc1ccc(/C=N/NC(=O)c2ccccn2)c(O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P08 compound treatment 56560.0 -48500.0 -1.5 97720.0 -23000.0 -0.6 -1.4841 -0.9185 3213664 CHDI2_001385 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P09 compound treatment 58920.0 -46100.0 -1.43 87320.0 -33400.0 -0.87 -1.6235 -0.9715 3552688 CHDI2_001386 COc1ccc(O)c(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P10 compound treatment 57880.0 -47100.0 -1.46 99120.0 -21600.0 -0.56 -1.4295 -0.9137 3214778 CHDI2_001387 ONC(=O)CCCCCC(=O)N/N=C/c1cc(Br)c(O)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P11 compound treatment 52280.0 -52700.0 -1.63 79920.0 -40800.0 -1.06 -1.9049 -0.9781 3552973 CHDI2_001388 CN(CCO)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P12 compound treatment 71760.0 -33300.0 -1.03 104440.0 -16300.0 -0.42 -1.0276 -0.9227 3214780 CHDI2_001389 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P13 compound treatment 72160.0 -32900.0 -1.02 99280.0 -21400.0 -0.56 -1.1137 -0.9598 3552692 CHDI2_001390 COc1cc(/C=C/C=N/NC(=O)c2ccccn2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P14 compound treatment 63240.0 -41800.0 -1.29 100000.0 -20700.0 -0.54 -1.2959 -0.9245 3214820 CHDI2_001391 CN(CCO)c1ccc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P15 compound treatment 62920.0 -42100.0 -1.3 87520.0 -33200.0 -0.86 -1.5322 -0.9799 3552696 CHDI2_001392 Cc1ccc(O)c(/C=N/NC(=O)c2ccccn2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P16 compound treatment 72480.0 -32500.0 -1.01 94840.0 -25900.0 -0.67 -1.1882 -0.9807 3215388 CHDI2_001393 ONC(=O)CCCCC(=O)N/N=C/c1cc(Br)c(O)c(Br)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P17 compound treatment 71440.0 -33600.0 -1.04 90760.0 -30000.0 -0.78 -1.286 -0.9898 3552700 CHDI2_001394 OCc1ccc(/C=N/NC(=O)c2ccccn2)o1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P18 compound treatment 61720.0 -43300.0 -1.34 99320.0 -21400.0 -0.56 -1.3417 -0.924 3215432 CHDI2_001395 CN(CCO)c1ccc(/C=N/NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P19 compound treatment 72480.0 -32500.0 -1.01 75720.0 -45000.0 -1.17 -1.5395 -0.9973 3552703 CHDI2_001396 Oc1c(/C=N/NC(=O)c2ccccn2)ccc3ccccc13 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P20 compound treatment 74680.0 -30300.0 -0.94 92320.0 -28400.0 -0.74 -1.1863 -0.9928 3553350 CHDI2_001397 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P21 compound treatment 50760.0 -54300.0 -1.68 60680.0 -60000.0 -1.56 -2.2917 -0.9993 3552707 CHDI2_001398 Clc1cccc(c1)c2ccc(/C=N/NC(=O)c3ccccn3)o2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P22 compound treatment 75280.0 -29700.0 -0.92 97440.0 -23300.0 -0.6 -1.0791 -0.9792 3553954 CHDI2_001399 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P23 mock treatment 100080.0 -4930.0 -0.15 103840.0 -16900.0 -0.44 -0.4182 -0.9003 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2406 P24 mock treatment 71760.0 -33300.0 -1.03 64800.0 -55900.0 -1.45 -1.7559 -0.9858 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A01 compound treatment 64080.0 -49100.0 -1.52 68880.0 -44100.0 -1.15 -1.8866 -0.9903 3553992 CHDI2_001400 Cc1[nH]cnc1/C=N/NC(=O)c2ccc(cc2)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A02 compound treatment 70160.0 -43000.0 -1.33 52760.0 -60300.0 -1.57 -2.0495 -0.9968 3634596 CHDI2_001401 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A03 compound treatment 17160.0 -96000.0 -2.97 11440.0 -102000.0 -2.64 -3.9699 -0.9982 3551957 CHDI2_001402 Oc1ccccc1C(=O)N/N=C/C(=C/c2ccccc2)/Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A04 compound treatment 10760.0 -102000.0 -3.17 4680.0 -108000.0 -2.81 -4.2343 -0.9982 3634598 CHDI2_001403 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A05 compound treatment 164040.0 50900.0 1.58 96880.0 -16100.0 -0.42 0.8179 0.5015 3552237 CHDI2_001404 Cc1[nH]cnc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A06 compound treatment 157920.0 44700.0 1.39 65680.0 -47300.0 -1.23 0.1106 0.0597 3634600 CHDI2_001405 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OC/C=C/COc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A07 compound treatment 151040.0 37900.0 1.17 52160.0 -60900.0 -1.58 -0.2885 -0.1465 3552453 CHDI2_001406 Br/C(=C\c1ccccc1)/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A08 compound treatment 7440.0 -106000.0 -3.28 3560.0 -109000.0 -2.84 -4.3276 -0.9975 3634602 CHDI2_001407 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A09 compound treatment 23160.0 -90000.0 -2.79 11440.0 -102000.0 -2.64 -3.8384 -0.9996 3634604 CHDI2_001408 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN3CCCCCCC3)CC(O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A10 compound treatment 126360.0 13200.0 0.41 61840.0 -51200.0 -1.33 -0.6514 -0.4683 3634605 CHDI2_001409 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A11 compound treatment 183320.0 70100.0 2.17 73320.0 -39700.0 -1.03 0.8075 0.3356 3562114 CHDI2_001410 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A12 compound treatment 7000.0 -106000.0 -3.29 4760.0 -108000.0 -2.81 -4.3152 -0.997 3634607 CHDI2_001411 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A13 compound treatment 86560.0 -26600.0 -0.82 51000.0 -62000.0 -1.61 -1.7225 -0.9516 3561878 CHDI2_001412 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A14 compound treatment 9240.0 -104000.0 -3.22 5960.0 -107000.0 -2.78 -4.2441 -0.9973 3634609 CHDI2_001413 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A15 compound treatment 166240.0 53100.0 1.64 103600.0 -9420.0 -0.24 0.9896 0.5953 3614528 CHDI2_001414 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A16 compound treatment 13760.0 -99400.0 -3.08 6560.0 -106000.0 -2.77 -4.134 -0.9986 3634611 CHDI2_001415 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A17 compound treatment 169560.0 56400.0 1.75 86280.0 -26700.0 -0.69 0.7441 0.3958 3614462 CHDI2_001416 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A18 compound treatment 160040.0 46900.0 1.45 7280.0 -106000.0 -2.75 -0.9159 -0.2947 3634613 CHDI2_001417 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A19 compound treatment 95400.0 -17800.0 -0.55 52720.0 -60300.0 -1.57 -1.4973 -0.9016 3614540 CHDI2_001418 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A20 compound treatment 15640.0 -97500.0 -3.02 8520.0 -104000.0 -2.72 -4.0568 -0.9986 3634615 CHDI2_001419 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A21 compound treatment 9680.0 -103000.0 -3.21 6040.0 -107000.0 -2.78 -4.233 -0.9975 3614392 CHDI2_001420 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A22 compound treatment 112560.0 -615.0 -0.02 79960.0 -33100.0 -0.86 -0.6208 -0.7226 3634617 CHDI2_001421 ONC(=O)CCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A23 mock treatment 142040.0 28900.0 0.89 103080.0 -9940.0 -0.26 0.4498 0.4832 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 A24 mock treatment 73480.0 -39700.0 -1.23 84640.0 -28400.0 -0.74 -1.3911 -0.9701 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B01 compound treatment 100040.0 -13100.0 -0.41 66440.0 -46600.0 -1.21 -1.1435 -0.8956 3634619 CHDI2_001422 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B02 compound treatment 109520.0 -3660.0 -0.11 79800.0 -33200.0 -0.86 -0.6904 -0.7931 3634621 CHDI2_001423 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B03 compound treatment 166800.0 53600.0 1.66 120840.0 7820.0 0.2 1.3186 0.7877 3634623 CHDI2_001424 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B04 compound treatment 183240.0 70100.0 2.17 81560.0 -31500.0 -0.82 0.9571 0.4126 3634625 CHDI2_001425 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B05 compound treatment 163760.0 50600.0 1.57 116280.0 3260.0 0.08 1.1682 0.7443 3634627 CHDI2_001426 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B06 compound treatment 187240.0 74100.0 2.29 88160.0 -24900.0 -0.65 1.166 0.4891 3634629 CHDI2_001427 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OC/C=C/COc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B07 compound treatment 55720.0 -57500.0 -1.78 20080.0 -92900.0 -2.41 -2.9663 -0.9888 3634631 CHDI2_001428 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B08 compound treatment 142320.0 29100.0 0.9 62200.0 -50800.0 -1.32 -0.2951 -0.1845 3634633 CHDI2_001429 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B09 compound treatment 154240.0 41100.0 1.27 92760.0 -20300.0 -0.53 0.5275 0.3831 3634635 CHDI2_001430 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B10 compound treatment 146560.0 33400.0 1.03 77600.0 -35400.0 -0.92 0.0807 0.0583 3634637 CHDI2_001431 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B11 compound treatment 16280.0 -96900.0 -3.0 8920.0 -104000.0 -2.7 -4.0355 -0.9986 3634639 CHDI2_001432 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B12 compound treatment 152720.0 39500.0 1.23 108000.0 -5020.0 -0.13 0.7742 0.6283 3634641 CHDI2_001433 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B13 compound treatment 153000.0 39800.0 1.23 98200.0 -14800.0 -0.39 0.6003 0.4644 3634643 CHDI2_001434 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B14 compound treatment 154720.0 41500.0 1.29 97040.0 -16000.0 -0.42 0.6167 0.4559 3634645 CHDI2_001435 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B15 compound treatment 45200.0 -68000.0 -2.11 20600.0 -92400.0 -2.4 -3.1872 -0.9979 3634647 CHDI2_001436 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B16 compound treatment 142320.0 29100.0 0.9 64440.0 -48600.0 -1.26 -0.254 -0.1636 3634649 CHDI2_001437 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B17 compound treatment 166120.0 52900.0 1.64 75120.0 -37900.0 -0.98 0.4637 0.2424 3634651 CHDI2_001438 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B18 compound treatment 166400.0 53200.0 1.65 68040.0 -45000.0 -1.17 0.3398 0.1681 3634653 CHDI2_001439 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B19 compound treatment 195000.0 81800.0 2.54 86920.0 -26100.0 -0.68 1.3132 0.5004 3634655 CHDI2_001440 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B20 compound treatment 168960.0 55800.0 1.73 100160.0 -12900.0 -0.33 0.986 0.5601 3634657 CHDI2_001441 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B21 compound treatment 169880.0 56700.0 1.76 89080.0 -23900.0 -0.62 0.8026 0.4306 3634659 CHDI2_001442 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B22 compound treatment 147680.0 34500.0 1.07 82960.0 -30100.0 -0.78 0.2037 0.1539 3634661 CHDI2_001443 ONC(=O)CCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B23 mock treatment 181480.0 68300.0 2.12 121360.0 8340.0 0.22 1.6498 0.7755 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 B24 mock treatment 133040.0 19900.0 0.62 95000.0 -18000.0 -0.47 0.1042 0.1347 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C01 compound treatment 24440.0 -88700.0 -2.75 20320.0 -92700.0 -2.41 -3.6472 -0.9978 3554029 CHDI2_001444 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C02 compound treatment 33000.0 -80200.0 -2.48 15720.0 -97300.0 -2.53 -3.5442 -1.0 3634663 CHDI2_001445 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C03 compound treatment 112040.0 -1140.0 -0.04 81600.0 -31400.0 -0.82 -0.6021 -0.7369 3551993 CHDI2_001446 Oc1ccc(Br)cc1/C=N/NC(=O)c2ccccc2O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C04 compound treatment 133800.0 20600.0 0.64 80360.0 -32700.0 -0.85 -0.1481 -0.1394 3634665 CHDI2_001447 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C05 compound treatment 121360.0 8180.0 0.25 55440.0 -57600.0 -1.5 -0.8785 -0.579 3552272 CHDI2_001448 Oc1ccccc1C(=O)N/N=C/c2cccc(Oc3ccccc3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C06 compound treatment 57040.0 -56100.0 -1.74 20440.0 -92600.0 -2.41 -2.9308 -0.9873 3634667 CHDI2_001449 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OC/C=C/COc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C07 compound treatment 120120.0 6940.0 0.22 80720.0 -32300.0 -0.84 -0.4412 -0.5093 3552490 CHDI2_001450 Oc1ccc(Br)cc1/C=N/NC(=O)c2ccccn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C08 compound treatment 8880.0 -104000.0 -3.23 5640.0 -107000.0 -2.79 -4.2578 -0.9973 3634669 CHDI2_001451 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C09 compound treatment 19120.0 -94100.0 -2.91 8120.0 -105000.0 -2.73 -3.9879 -0.9994 3634671 CHDI2_001452 CN(CC=C)CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C10 compound treatment 142040.0 28900.0 0.89 80800.0 -32200.0 -0.84 0.0405 0.0331 3634672 CHDI2_001453 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C11 compound treatment 12400.0 -101000.0 -3.12 6400.0 -107000.0 -2.77 -4.1668 -0.9982 3634674 CHDI2_001454 OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)O)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C12 compound treatment 9480.0 -104000.0 -3.21 7440.0 -106000.0 -2.74 -4.2116 -0.9969 3634675 CHDI2_001455 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C13 compound treatment 161080.0 47900.0 1.48 131400.0 18400.0 0.48 1.3873 0.8897 3614424 CHDI2_001456 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C14 compound treatment 149640.0 36500.0 1.13 84000.0 -29000.0 -0.75 0.2658 0.1957 3634677 CHDI2_001457 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C15 compound treatment 153640.0 40500.0 1.25 83840.0 -29200.0 -0.76 0.3505 0.2392 3614530 CHDI2_001458 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C16 compound treatment 12880.0 -100000.0 -3.11 9480.0 -104000.0 -2.69 -4.0997 -0.9974 3634679 CHDI2_001459 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C17 compound treatment 147760.0 34600.0 1.07 113480.0 463.0 0.01 0.7662 0.715 3614464 CHDI2_001460 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C18 compound treatment 161320.0 48100.0 1.49 71680.0 -41300.0 -1.07 0.2953 0.1607 3634681 CHDI2_001461 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C19 compound treatment 160760.0 47600.0 1.47 96480.0 -16500.0 -0.43 0.7387 0.481 3614594 CHDI2_001462 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C20 compound treatment 168480.0 55300.0 1.71 94280.0 -18700.0 -0.49 0.8674 0.4869 3634683 CHDI2_001463 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C21 compound treatment 35040.0 -78100.0 -2.42 17240.0 -95800.0 -2.49 -3.4716 -0.9999 3614389 CHDI2_001464 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C22 compound treatment 118960.0 5780.0 0.18 82920.0 -30100.0 -0.78 -0.4262 -0.5313 3634685 CHDI2_001465 ONC(=O)CCCCCCC(=O)N/N=C/c1cccc(OCCCCCCCCCCCCOc2cccc(\C=N\NC(=O)CCCCCCC(=O)NO)c2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C23 mock treatment 178600.0 65400.0 2.03 134840.0 21800.0 0.57 1.8344 0.8714 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 C24 mock treatment 145680.0 32500.0 1.01 116640.0 3620.0 0.09 0.7787 0.7698 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D01 compound treatment 93640.0 -19500.0 -0.61 50680.0 -62300.0 -1.62 -1.5733 -0.9099 3634687 CHDI2_001466 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D02 compound treatment 120000.0 6820.0 0.21 84440.0 -28600.0 -0.74 -0.3755 -0.4864 3634689 CHDI2_001467 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D03 compound treatment 113080.0 -95.2 0.0 118400.0 5380.0 0.14 0.0968 0.692 3634691 CHDI2_001468 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D04 compound treatment 133000.0 19800.0 0.61 90480.0 -22500.0 -0.59 0.0203 0.0239 3634693 CHDI2_001469 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D05 compound treatment 117040.0 3860.0 0.12 109360.0 -3660.0 -0.1 0.0175 0.1143 3634695 CHDI2_001470 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D06 compound treatment 107640.0 -5540.0 -0.17 87040.0 -26000.0 -0.67 -0.5985 -0.8595 3634697 CHDI2_001471 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D07 compound treatment 89080.0 -24100.0 -0.75 107040.0 -5980.0 -0.16 -0.6377 -0.8363 3634699 CHDI2_001472 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D08 compound treatment 107400.0 -5780.0 -0.18 96960.0 -16100.0 -0.42 -0.4215 -0.9286 3634701 CHDI2_001473 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D09 compound treatment 95360.0 -17800.0 -0.55 104880.0 -8140.0 -0.21 -0.5398 -0.9133 3634703 CHDI2_001474 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D10 compound treatment 98040.0 -15100.0 -0.47 99880.0 -13100.0 -0.34 -0.573 -0.9878 3634705 CHDI2_001475 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D11 compound treatment 99000.0 -14200.0 -0.44 99360.0 -13700.0 -0.35 -0.5615 -0.9944 3634707 CHDI2_001476 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D12 compound treatment 127560.0 14400.0 0.45 111320.0 -1700.0 -0.04 0.284 0.634 3634709 CHDI2_001477 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D13 compound treatment 113800.0 625.0 0.02 109520.0 -3500.0 -0.09 -0.0506 -0.5443 3634711 CHDI2_001478 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D14 compound treatment 122160.0 8980.0 0.28 98520.0 -14500.0 -0.38 -0.0695 -0.1484 3634713 CHDI2_001479 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D15 compound treatment 128960.0 15800.0 0.49 91960.0 -21100.0 -0.55 -0.041 -0.0559 3634715 CHDI2_001480 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D16 compound treatment 95840.0 -17300.0 -0.54 93800.0 -19200.0 -0.5 -0.7329 -0.9993 3634717 CHDI2_001481 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D17 compound treatment 114800.0 1620.0 0.05 93520.0 -19500.0 -0.51 -0.3226 -0.6337 3634719 CHDI2_001482 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D18 compound treatment 111960.0 -1220.0 -0.04 90640.0 -22400.0 -0.58 -0.4378 -0.7513 3634721 CHDI2_001483 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D19 compound treatment 138600.0 25400.0 0.79 100440.0 -12600.0 -0.33 0.326 0.3822 3634723 CHDI2_001484 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D20 compound treatment 122480.0 9300.0 0.29 77640.0 -35400.0 -0.92 -0.4461 -0.4631 3634725 CHDI2_001485 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D21 compound treatment 124600.0 11400.0 0.35 93360.0 -19700.0 -0.51 -0.1108 -0.1784 3634727 CHDI2_001486 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D22 compound treatment 126040.0 12900.0 0.4 105000.0 -8020.0 -0.21 0.1346 0.2992 3634729 CHDI2_001487 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D23 mock treatment 169880.0 56700.0 1.76 107000.0 -6020.0 -0.16 1.1318 0.6416 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 D24 mock treatment 140360.0 27200.0 0.84 101960.0 -11100.0 -0.29 0.3924 0.441 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E01 compound treatment 133280.0 20100.0 0.62 48960.0 -64100.0 -1.66 -0.7364 -0.4144 3554048 CHDI2_001488 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2nccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E02 compound treatment 113960.0 785.0 0.02 83760.0 -29300.0 -0.76 -0.5203 -0.6841 3634731 CHDI2_001489 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E03 compound treatment 155160.0 42000.0 1.3 123000.0 9980.0 0.26 1.1033 0.8317 3552029 CHDI2_001490 OC(=O)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E04 compound treatment 128440.0 15300.0 0.47 92320.0 -20700.0 -0.54 -0.0458 -0.064 3634733 CHDI2_001491 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E05 compound treatment 109800.0 -3380.0 -0.1 129280.0 16300.0 0.42 0.2248 0.5165 3552300 CHDI2_001492 Oc1ccccc1C(=O)N/N=C/c2nccs2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E06 compound treatment 153400.0 40200.0 1.25 90400.0 -22600.0 -0.59 0.4658 0.338 3634735 CHDI2_001493 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E07 compound treatment 111200.0 -1980.0 -0.06 106680.0 -6340.0 -0.16 -0.1597 -0.9091 3552525 CHDI2_001494 OC(=O)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E08 compound treatment 32000.0 -81200.0 -2.52 21640.0 -91400.0 -2.37 -3.4573 -0.9996 3634737 CHDI2_001495 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E09 compound treatment 8640.0 -105000.0 -3.24 7720.0 -105000.0 -2.74 -4.2249 -0.9965 3634739 CHDI2_001496 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3)Cc4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E10 compound treatment 111920.0 -1260.0 -0.04 68520.0 -44500.0 -1.16 -0.845 -0.7305 3634740 CHDI2_001497 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E11 compound treatment 42440.0 -70700.0 -2.19 29360.0 -83700.0 -2.17 -3.0868 -1.0 3634742 CHDI2_001498 CN(C[C@H]1C[C@H](OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccc(CO)cc3)Cc4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E12 compound treatment 112200.0 -975.0 -0.03 114320.0 1300.0 0.03 0.0026 0.0565 3634743 CHDI2_001499 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E13 compound treatment 123440.0 10300.0 0.32 118320.0 5300.0 0.14 0.3223 0.9299 3614478 CHDI2_001500 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E14 compound treatment 129240.0 16100.0 0.5 92600.0 -20400.0 -0.53 -0.0232 -0.0318 3634745 CHDI2_001501 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E15 compound treatment 145960.0 32800.0 1.02 109680.0 -3340.0 -0.09 0.657 0.6444 3614432 CHDI2_001502 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E16 compound treatment 113400.0 225.0 0.01 67120.0 -45900.0 -1.19 -0.8383 -0.703 3634747 CHDI2_001503 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E17 compound treatment 115920.0 2740.0 0.09 109840.0 -3180.0 -0.08 0.0018 0.0148 3614467 CHDI2_001504 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E18 compound treatment 112120.0 -1060.0 -0.03 76560.0 -36500.0 -0.95 -0.6929 -0.7311 3634749 CHDI2_001505 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E19 compound treatment 141760.0 28600.0 0.89 103880.0 -9140.0 -0.24 0.4584 0.4999 3614596 CHDI2_001506 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E20 compound treatment 124680.0 11500.0 0.36 87360.0 -25700.0 -0.67 -0.2193 -0.2901 3634751 CHDI2_001507 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E21 compound treatment 152120.0 38900.0 1.21 124120.0 11100.0 0.29 1.0572 0.8521 3614386 CHDI2_001508 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E22 compound treatment 114200.0 1020.0 0.03 91400.0 -21600.0 -0.56 -0.3747 -0.6661 3634753 CHDI2_001509 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E23 mock treatment 128360.0 15200.0 0.47 123200.0 10200.0 0.26 0.5198 0.9629 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 E24 mock treatment 140040.0 26900.0 0.83 89960.0 -23100.0 -0.6 0.165 0.1609 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F01 compound treatment 170520.0 57300.0 1.78 84120.0 -28900.0 -0.75 0.7255 0.3761 3634755 CHDI2_001510 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F02 compound treatment 145880.0 32700.0 1.01 87280.0 -25700.0 -0.67 0.2437 0.2007 3634757 CHDI2_001511 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F03 compound treatment 131560.0 18400.0 0.57 99520.0 -13500.0 -0.35 0.1548 0.2314 3634759 CHDI2_001512 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F04 compound treatment 101600.0 -11600.0 -0.36 86080.0 -26900.0 -0.7 -0.7485 -0.9518 3634761 CHDI2_001513 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F05 compound treatment 106960.0 -6220.0 -0.19 117600.0 4580.0 0.12 -0.052 -0.2296 3634763 CHDI2_001514 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F06 compound treatment 110680.0 -2500.0 -0.08 112640.0 -378.0 -0.01 -0.0616 -0.7905 3634765 CHDI2_001515 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F07 compound treatment 99720.0 -13500.0 -0.42 107320.0 -5700.0 -0.15 -0.3995 -0.903 3634767 CHDI2_001516 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F08 compound treatment 110480.0 -2700.0 -0.08 92080.0 -20900.0 -0.54 -0.4437 -0.8062 3634769 CHDI2_001517 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F09 compound treatment 94880.0 -18300.0 -0.57 117720.0 4700.0 0.12 -0.3144 -0.5422 3634771 CHDI2_001518 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F10 compound treatment 101360.0 -11800.0 -0.37 103320.0 -9700.0 -0.25 -0.437 -0.9834 3634773 CHDI2_001519 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F11 compound treatment 103280.0 -9900.0 -0.31 102320.0 -10700.0 -0.28 -0.4133 -0.9988 3634775 CHDI2_001520 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F12 compound treatment 99600.0 -13600.0 -0.42 96520.0 -16500.0 -0.43 -0.6005 -1.0 3634777 CHDI2_001521 CCOc1cc(/C=N/NC(=O)CCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F13 compound treatment 10280.0 -103000.0 -3.19 9480.0 -104000.0 -2.69 -4.1566 -0.9964 3634779 CHDI2_001522 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F14 compound treatment 99920.0 -13300.0 -0.41 85160.0 -27900.0 -0.72 -0.8022 -0.964 3634781 CHDI2_001523 COc1cc(OC/C=C/COc2cc(OC)c(\C=N\NC(=O)CCCCC(=O)NO)c(OC)c2)cc(OC)c1\C=N\NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F15 compound treatment 10120.0 -103000.0 -3.19 8480.0 -105000.0 -2.72 -4.1785 -0.9968 3634783 CHDI2_001524 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F16 compound treatment 101600.0 -11600.0 -0.36 94000.0 -19000.0 -0.49 -0.603 -0.9876 3634785 CHDI2_001525 COc1cc(OCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F17 compound treatment 12520.0 -101000.0 -3.12 9680.0 -103000.0 -2.68 -4.1039 -0.9972 3634787 CHDI2_001526 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F18 compound treatment 101320.0 -11900.0 -0.37 77840.0 -35200.0 -0.91 -0.906 -0.9198 3634789 CHDI2_001527 COc1cc(OCCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F19 compound treatment 131760.0 18600.0 0.58 106600.0 -6420.0 -0.17 0.2893 0.4825 3634791 CHDI2_001528 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F20 compound treatment 107000.0 -6180.0 -0.19 86080.0 -26900.0 -0.7 -0.6302 -0.8685 3634793 CHDI2_001529 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OC\C=C\COc2c(OC)cc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F21 compound treatment 139600.0 26400.0 0.82 81560.0 -31500.0 -0.82 0.001 9.0E-4 3634795 CHDI2_001530 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F22 compound treatment 120280.0 7100.0 0.22 81960.0 -31100.0 -0.81 -0.4149 -0.4961 3634797 CHDI2_001531 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F23 mock treatment 132520.0 19300.0 0.6 127920.0 14900.0 0.39 0.6976 0.9776 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 F24 mock treatment 135240.0 22100.0 0.68 101880.0 -11100.0 -0.29 0.2788 0.3755 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G01 compound treatment 152120.0 38900.0 1.21 108600.0 -4420.0 -0.11 0.7721 0.637 3554086 CHDI2_001532 NC(=O)COc1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G02 compound treatment 91640.0 -21500.0 -0.67 77640.0 -35400.0 -0.92 -1.1218 -0.9876 3634799 CHDI2_001533 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G03 compound treatment 104520.0 -8660.0 -0.27 83880.0 -29100.0 -0.76 -0.725 -0.9026 3552065 CHDI2_001534 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G04 compound treatment 105560.0 -7620.0 -0.24 85200.0 -27800.0 -0.72 -0.6779 -0.8916 3634801 CHDI2_001535 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G05 compound treatment 103080.0 -10100.0 -0.31 114080.0 1060.0 0.03 -0.2017 -0.6422 3552337 CHDI2_001536 NC(=O)COc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G06 compound treatment 108800.0 -4380.0 -0.14 91320.0 -21700.0 -0.56 -0.4945 -0.8528 3634803 CHDI2_001537 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G07 compound treatment 11720.0 -101000.0 -3.14 11160.0 -102000.0 -2.65 -4.0942 -0.9963 3552561 CHDI2_001538 CCCCN(CCCC)c1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G08 compound treatment 86520.0 -26700.0 -0.83 76400.0 -36600.0 -0.95 -1.2568 -0.9975 3634805 CHDI2_001539 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G09 compound treatment 11520.0 -102000.0 -3.15 12320.0 -101000.0 -2.62 -4.0773 -0.9957 3634807 CHDI2_001540 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(OC(O2)c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G10 compound treatment 99000.0 -14200.0 -0.44 80840.0 -32200.0 -0.84 -0.9018 -0.9548 3634808 CHDI2_001541 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G11 compound treatment 78720.0 -34500.0 -1.07 66000.0 -47000.0 -1.22 -1.6187 -0.9977 3634810 CHDI2_001542 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)c2ccc(NC(=O)CCCC#C)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G12 compound treatment 99360.0 -13800.0 -0.43 100120.0 -12900.0 -0.34 -0.5396 -0.9927 3634811 CHDI2_001543 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G13 compound treatment 83080.0 -30100.0 -0.93 102080.0 -10900.0 -0.28 -0.8603 -0.8825 3614494 CHDI2_001544 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G14 compound treatment 92920.0 -20300.0 -0.63 86680.0 -26300.0 -0.68 -0.9277 -0.9991 3634813 CHDI2_001545 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G15 compound treatment 99840.0 -13300.0 -0.41 118120.0 5100.0 0.13 -0.1984 -0.4573 3614437 CHDI2_001546 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G16 compound treatment 78720.0 -34500.0 -1.07 70440.0 -42600.0 -1.11 -1.5372 -0.9998 3634815 CHDI2_001547 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G17 compound treatment 81160.0 -32000.0 -0.99 53760.0 -59300.0 -1.54 -1.7901 -0.9774 3614479 CHDI2_001548 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G18 compound treatment 87800.0 -25400.0 -0.79 89600.0 -23400.0 -0.61 -0.9862 -0.992 3634817 CHDI2_001549 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G19 compound treatment 110720.0 -2460.0 -0.08 97480.0 -15500.0 -0.4 -0.3393 -0.8258 3614693 CHDI2_001550 COC(=O)c1cn(CC(=O)O)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G20 compound treatment 86440.0 -26700.0 -0.83 79200.0 -33800.0 -0.88 -1.2071 -0.9996 3634819 CHDI2_001551 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G21 compound treatment 8280.0 -105000.0 -3.25 6520.0 -106000.0 -2.77 -4.2548 -0.9968 3614403 CHDI2_001552 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G22 compound treatment 86760.0 -26400.0 -0.82 73360.0 -39700.0 -1.03 -1.3074 -0.9935 3634821 CHDI2_001553 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCCCCCCCCCCCCOc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G23 mock treatment 110560.0 -2620.0 -0.08 115960.0 2940.0 0.08 -0.0032 -0.029 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 G24 mock treatment 104520.0 -8660.0 -0.27 125720.0 12700.0 0.33 0.0437 0.1029 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H01 compound treatment 129960.0 16800.0 0.52 107240.0 -5780.0 -0.15 0.2616 0.4833 3634823 CHDI2_001554 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H02 compound treatment 128000.0 14800.0 0.46 105640.0 -7380.0 -0.19 0.1893 0.3802 3634825 CHDI2_001555 COc1cc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCC(=O)NO)c(OC)c2)ccc1\C=N\NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H03 compound treatment 110760.0 -2420.0 -0.07 93760.0 -19300.0 -0.5 -0.4067 -0.8039 3634827 CHDI2_001556 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H04 compound treatment 110080.0 -3100.0 -0.1 106240.0 -6780.0 -0.18 -0.1923 -0.9592 3634829 CHDI2_001557 COc1cc(OCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H05 compound treatment 107600.0 -5580.0 -0.17 112920.0 -97.5 0.0 -0.1239 -0.7174 3634831 CHDI2_001558 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H06 compound treatment 112360.0 -815.0 -0.03 104520.0 -8500.0 -0.22 -0.174 -0.7829 3634833 CHDI2_001559 COc1cc(OCCCCCCOc2ccc(/C=N/NC(=O)CCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H07 compound treatment 103480.0 -9700.0 -0.3 106040.0 -6980.0 -0.18 -0.3406 -0.9708 3634835 CHDI2_001560 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H08 compound treatment 104240.0 -8940.0 -0.28 113240.0 223.0 0.01 -0.1917 -0.6922 3634837 CHDI2_001561 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccc(COc3ccc(\C=N\NC(=O)CCCCC(=O)NO)cc3)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H09 compound treatment 94640.0 -18500.0 -0.57 74480.0 -38500.0 -1.0 -1.1141 -0.9652 3634839 CHDI2_001562 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H10 compound treatment 104920.0 -8260.0 -0.26 89760.0 -23300.0 -0.6 -0.6082 -0.9268 3634841 CHDI2_001563 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2cccc(COc3ccc(\C=N\NC(=O)CCCCC(=O)NO)cc3)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H11 compound treatment 33280.0 -79900.0 -2.48 29800.0 -83200.0 -2.16 -3.2794 -0.9977 3634843 CHDI2_001564 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H12 compound treatment 98760.0 -14400.0 -0.45 101280.0 -11700.0 -0.3 -0.5315 -0.9827 3634845 CHDI2_001565 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccccc2COc3ccc(\C=N\NC(=O)CCCCC(=O)NO)cc3)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H13 compound treatment 9440.0 -104000.0 -3.21 9520.0 -103000.0 -2.69 -4.1743 -0.9961 3634847 CHDI2_001566 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H14 compound treatment 108840.0 -4340.0 -0.13 95480.0 -17500.0 -0.46 -0.4172 -0.8782 3634849 CHDI2_001567 ONC(=O)CCCCC(=O)N/N=C/c1ccc(OCc2ccccc2c3ccccc3COc4ccc(\C=N\NC(=O)CCCCC(=O)NO)cc4)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H15 compound treatment 105600.0 -7580.0 -0.23 98160.0 -14900.0 -0.39 -0.4389 -0.9715 3634851 CHDI2_001568 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H16 compound treatment 77920.0 -35300.0 -1.09 82320.0 -30700.0 -0.8 -1.3364 -0.9881 3634853 CHDI2_001569 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H17 compound treatment 109560.0 -3620.0 -0.11 102040.0 -11000.0 -0.29 -0.2809 -0.9166 3634855 CHDI2_001570 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H18 compound treatment 102480.0 -10700.0 -0.33 98800.0 -14200.0 -0.37 -0.4955 -0.9985 3634857 CHDI2_001571 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H19 compound treatment 9280.0 -104000.0 -3.22 9640.0 -103000.0 -2.69 -4.1756 -0.9959 3634859 CHDI2_001572 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H20 compound treatment 80000.0 -33200.0 -1.03 87800.0 -25200.0 -0.66 -1.1902 -0.9764 3634861 CHDI2_001573 Cc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)c(O)c(/C=N/NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H21 compound treatment 16120.0 -97100.0 -3.01 13680.0 -99300.0 -2.58 -3.9515 -0.9971 3634863 CHDI2_001574 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H22 compound treatment 113600.0 425.0 0.01 108960.0 -4060.0 -0.11 -0.0652 -0.6141 3634865 CHDI2_001575 Cc1cc(/C=N/NC(=O)CCCCCC(=O)NO)c(O)c(/C=N/NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H23 mock treatment 124400.0 11200.0 0.35 113640.0 623.0 0.02 0.2574 0.7392 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 H24 mock treatment 82800.0 -30400.0 -0.94 93200.0 -19800.0 -0.51 -1.0296 -0.9597 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I01 compound treatment 60480.0 -52700.0 -1.63 47720.0 -65300.0 -1.7 -2.3542 -0.9998 3554221 CHDI2_001576 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCC#C)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I02 compound treatment 94960.0 -18200.0 -0.56 89040.0 -24000.0 -0.62 -0.8396 -0.9988 3634867 CHDI2_001577 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I03 compound treatment 115640.0 2460.0 0.08 103920.0 -9100.0 -0.24 -0.1131 -0.4555 1922557 CHDI2_001578 COc1ccc(/C=N/NC(=O)c2ccccc2O)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I04 compound treatment 71160.0 -42000.0 -1.3 74800.0 -38200.0 -0.99 -1.6227 -0.9911 3634869 CHDI2_001579 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I05 compound treatment 111880.0 -1300.0 -0.04 119720.0 6700.0 0.17 0.0948 0.5303 3552422 CHDI2_001580 Oc1ccccc1C(=O)N/N=C/c2ccc(OCC#C)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I06 compound treatment 110000.0 -3180.0 -0.1 127280.0 14300.0 0.37 0.1925 0.502 3634871 CHDI2_001581 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I07 compound treatment 95280.0 -17900.0 -0.55 116800.0 3780.0 0.1 -0.3226 -0.5728 3552599 CHDI2_001582 COc1ccc(/C=N/NC(=O)c2ccccn2)c(OC)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I08 compound treatment 60960.0 -52200.0 -1.62 69560.0 -43500.0 -1.13 -1.9424 -0.9845 3634873 CHDI2_001583 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I09 compound treatment 99400.0 -13800.0 -0.43 103560.0 -9460.0 -0.25 -0.4756 -0.9656 3634875 CHDI2_001584 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)NCCOCCOCCNC(=O)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I10 compound treatment 99960.0 -13200.0 -0.41 100920.0 -12100.0 -0.31 -0.5118 -0.9915 3634876 CHDI2_001585 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I11 compound treatment 15440.0 -97700.0 -3.03 16480.0 -96500.0 -2.51 -3.915 -0.9956 468 CHDI2_001586 ONC(=O)CCCCCCC(=O)Nc1ccccc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I12 compound treatment 102160.0 -11000.0 -0.34 101960.0 -11100.0 -0.29 -0.4445 -0.9963 3634878 CHDI2_001587 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I13 compound treatment 92920.0 -20300.0 -0.63 111560.0 -1460.0 -0.04 -0.4706 -0.7484 3614495 CHDI2_001588 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I14 compound treatment 129400.0 16200.0 0.5 109960.0 -3060.0 -0.08 0.2993 0.5881 3634880 CHDI2_001589 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I15 compound treatment 47560.0 -65600.0 -2.03 38880.0 -74100.0 -1.93 -2.7997 -0.9996 3614442 CHDI2_001590 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I16 compound treatment 101600.0 -11600.0 -0.36 116320.0 3300.0 0.09 -0.1929 -0.5232 3634882 CHDI2_001591 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I17 compound treatment 96520.0 -16700.0 -0.52 110720.0 -2300.0 -0.06 -0.4071 -0.7837 3614485 CHDI2_001592 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I18 compound treatment 102280.0 -10900.0 -0.34 116160.0 3140.0 0.08 -0.181 -0.5211 3634884 CHDI2_001593 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I19 compound treatment 111600.0 -1580.0 -0.05 97440.0 -15600.0 -0.4 -0.3207 -0.7867 3614695 CHDI2_001594 COC(=O)c1cn(CCC(=O)O)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I20 compound treatment 120240.0 7060.0 0.22 102640.0 -10400.0 -0.27 -0.0359 -0.1033 3634886 CHDI2_001595 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I21 compound treatment 8400.0 -105000.0 -3.25 7920.0 -105000.0 -2.73 -4.2265 -0.9963 3614398 CHDI2_001596 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I22 compound treatment 111040.0 -2140.0 -0.07 105960.0 -7060.0 -0.18 -0.1764 -0.9051 3634888 CHDI2_001597 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I23 mock treatment 107000.0 -6180.0 -0.19 127440.0 14400.0 0.37 0.1297 0.3082 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 I24 mock treatment 96760.0 -16400.0 -0.51 110560.0 -2460.0 -0.06 -0.4048 -0.7897 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J01 compound treatment 154960.0 41800.0 1.29 157200.0 44200.0 1.15 1.7272 0.9982 3634890 CHDI2_001598 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J02 compound treatment 135760.0 22600.0 0.7 105760.0 -7260.0 -0.19 0.3615 0.4988 3634892 CHDI2_001599 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J03 compound treatment 98840.0 -14300.0 -0.44 98520.0 -14500.0 -0.38 -0.5804 -0.9966 3634894 CHDI2_001600 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J04 compound treatment 112520.0 -655.0 -0.02 101120.0 -11900.0 -0.31 -0.2329 -0.7519 3634896 CHDI2_001601 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J05 compound treatment 108360.0 -4820.0 -0.15 117200.0 4180.0 0.11 -0.0287 -0.1552 3634898 CHDI2_001602 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J06 compound treatment 103760.0 -9420.0 -0.29 111560.0 -1460.0 -0.04 -0.2331 -0.7923 3634900 CHDI2_001603 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J07 compound treatment 100360.0 -12800.0 -0.4 114200.0 1180.0 0.03 -0.259 -0.6504 3634902 CHDI2_001604 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J08 compound treatment 95360.0 -17800.0 -0.55 92480.0 -20500.0 -0.53 -0.7676 -0.9999 3634904 CHDI2_001605 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J09 compound treatment 78320.0 -34900.0 -1.08 77240.0 -35800.0 -0.93 -1.421 -0.9972 3634906 CHDI2_001606 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J10 compound treatment 98960.0 -14200.0 -0.44 103840.0 -9180.0 -0.24 -0.4801 -0.9585 3634908 CHDI2_001607 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J11 compound treatment 91480.0 -21700.0 -0.67 113600.0 583.0 0.02 -0.4646 -0.691 3634910 CHDI2_001608 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J12 compound treatment 91040.0 -22100.0 -0.69 97360.0 -15700.0 -0.41 -0.7726 -0.9689 3634912 CHDI2_001609 CCOc1cc(/C=N/NC(=O)CCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J13 compound treatment 9440.0 -104000.0 -3.21 9920.0 -103000.0 -2.68 -4.1669 -0.9959 3634914 CHDI2_001610 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J14 compound treatment 98600.0 -14600.0 -0.45 103720.0 -9300.0 -0.24 -0.4902 -0.957 3634916 CHDI2_001611 COc1cc(OC/C=C/COc2cc(OC)c(\C=N\NC(=O)CCCCCC(=O)NO)c(OC)c2)cc(OC)c1\C=N\NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J15 compound treatment 7840.0 -105000.0 -3.26 8680.0 -104000.0 -2.71 -4.2248 -0.9957 3634918 CHDI2_001612 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J16 compound treatment 68360.0 -44800.0 -1.39 74760.0 -38300.0 -0.99 -1.6848 -0.9866 3634920 CHDI2_001613 COc1cc(OCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J17 compound treatment 7320.0 -106000.0 -3.28 9400.0 -104000.0 -2.69 -4.2229 -0.9952 3634922 CHDI2_001614 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J18 compound treatment 79080.0 -34100.0 -1.06 80720.0 -32300.0 -0.84 -1.3404 -0.9935 3634924 CHDI2_001615 COc1cc(OCCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J19 compound treatment 99560.0 -13600.0 -0.42 102600.0 -10400.0 -0.27 -0.4897 -0.977 3634926 CHDI2_001616 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J20 compound treatment 81480.0 -31700.0 -0.98 76920.0 -36100.0 -0.94 -1.3576 -0.9997 3634928 CHDI2_001617 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OC\C=C\COc2c(OC)cc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J21 compound treatment 69800.0 -43400.0 -1.34 84640.0 -28400.0 -0.74 -1.4717 -0.9601 3634930 CHDI2_001618 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J22 compound treatment 86320.0 -26900.0 -0.83 79280.0 -33700.0 -0.88 -1.2082 -0.9997 3634932 CHDI2_001619 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J23 mock treatment 110160.0 -3020.0 -0.09 113880.0 863.0 0.02 -0.0502 -0.5227 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 J24 mock treatment 101640.0 -11500.0 -0.36 106520.0 -6500.0 -0.17 -0.3721 -0.9414 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K01 compound treatment 113040.0 -135.0 0.0 166440.0 53400.0 1.39 0.9785 0.705 3552785 CHDI2_001620 CCCCCCC/C=N/NC(=O)c1ccccn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K02 compound treatment 119720.0 6540.0 0.2 99720.0 -13300.0 -0.35 -0.1009 -0.2519 3634934 CHDI2_001621 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K03 compound treatment 113800.0 625.0 0.02 110480.0 -2540.0 -0.07 -0.0329 -0.4792 3552859 CHDI2_001622 COc1cc(Br)c(/C=N/NC(=O)c2ccccn2)cc1OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K04 compound treatment 86880.0 -26300.0 -0.81 102960.0 -10100.0 -0.26 -0.7609 -0.8893 3634936 CHDI2_001623 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K05 compound treatment 108680.0 -4500.0 -0.14 97480.0 -15500.0 -0.4 -0.384 -0.8991 3552906 CHDI2_001624 COc1cc(/C=N/NC(=O)c2ccccn2)ccc1O 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K06 compound treatment 91520.0 -21700.0 -0.67 98600.0 -14400.0 -0.37 -0.7393 -0.9621 3634938 CHDI2_001625 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OC/C=C/COc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K07 compound treatment 90920.0 -22300.0 -0.69 99320.0 -13700.0 -0.36 -0.7393 -0.9527 3554243 CHDI2_001626 C/C(=N\NC(=O)c1ccccn1)/C[P+](c2ccccc2)(c3ccccc3)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K08 compound treatment 55480.0 -57700.0 -1.79 74720.0 -38300.0 -1.0 -1.9677 -0.9618 3634940 CHDI2_001627 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K09 compound treatment 87960.0 -25200.0 -0.78 113400.0 383.0 0.01 -0.5454 -0.6981 3634942 CHDI2_001628 ONC(=O)CCCCCCC(=O)Nc1cccc(c1)C(=O)NCCOCCOCCNC(=O)c2cccc(NC(=O)CCCCCCC(=O)NO)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K10 compound treatment 96840.0 -16300.0 -0.51 108240.0 -4780.0 -0.12 -0.4457 -0.8552 3634943 CHDI2_001629 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K11 compound treatment 83000.0 -30200.0 -0.93 70040.0 -43000.0 -1.12 -1.4507 -0.9961 3634945 CHDI2_001630 ONC(=O)/C=C/c1ccc(CN(CCC2=C[N]c3ccccc23)C(=O)CCCCC(=O)N(CCC4=C[N]c5ccccc45)Cc6ccc(\C=C\C(=O)NO)cc6)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K12 compound treatment 89480.0 -23700.0 -0.73 102560.0 -10500.0 -0.27 -0.7113 -0.9086 3634947 CHDI2_001631 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K13 compound treatment 81200.0 -32000.0 -0.99 94040.0 -19000.0 -0.49 -1.0492 -0.9481 3614498 CHDI2_001632 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K14 compound treatment 92800.0 -20400.0 -0.63 97680.0 -15300.0 -0.4 -0.7282 -0.9754 3634949 CHDI2_001633 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K15 compound treatment 102880.0 -10300.0 -0.32 106920.0 -6100.0 -0.16 -0.3376 -0.9478 3614446 CHDI2_001634 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K16 compound treatment 74040.0 -39100.0 -1.21 89240.0 -23800.0 -0.62 -1.2943 -0.951 3634951 CHDI2_001635 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K17 compound treatment 84160.0 -29000.0 -0.9 101760.0 -11300.0 -0.29 -0.8425 -0.8912 3614488 CHDI2_001636 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K18 compound treatment 90760.0 -22400.0 -0.69 100400.0 -12600.0 -0.33 -0.7229 -0.9413 3634953 CHDI2_001637 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K19 compound treatment 12000.0 -101000.0 -3.13 13400.0 -99600.0 -2.59 -4.0469 -0.9955 3614383 CHDI2_001638 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K20 compound treatment 101040.0 -12100.0 -0.38 88600.0 -24400.0 -0.63 -0.7145 -0.9688 3634955 CHDI2_001639 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K21 compound treatment 98160.0 -15000.0 -0.47 102280.0 -10700.0 -0.28 -0.5262 -0.9701 1917883 CHDI2_001640 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K22 compound treatment 83360.0 -29800.0 -0.92 82080.0 -30900.0 -0.8 -1.2216 -0.9976 3634957 CHDI2_001641 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2cccc(OCCCCCCCCCCCCOc3cccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)c3)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K23 mock treatment 102680.0 -10500.0 -0.33 106240.0 -6780.0 -0.18 -0.3545 -0.9585 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 K24 mock treatment 100560.0 -12600.0 -0.39 141480.0 28500.0 0.74 0.2465 0.2947 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L01 compound treatment 69800.0 -43400.0 -1.34 71080.0 -41900.0 -1.09 -1.7208 -0.9946 3634959 CHDI2_001642 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L02 compound treatment 172760.0 59600.0 1.85 108920.0 -4100.0 -0.11 1.2302 0.6652 3634961 CHDI2_001643 COc1cc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCC(=O)NO)c(OC)c2)ccc1\C=N\NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L03 compound treatment 9960.0 -103000.0 -3.2 10120.0 -103000.0 -2.67 -4.1519 -0.996 3634963 CHDI2_001644 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L04 compound treatment 102400.0 -10800.0 -0.33 114120.0 1100.0 0.03 -0.2158 -0.6441 3634965 CHDI2_001645 COc1cc(OCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L05 compound treatment 65640.0 -47500.0 -1.47 78760.0 -34300.0 -0.89 -1.6709 -0.9709 3634967 CHDI2_001646 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L06 compound treatment 98600.0 -14600.0 -0.45 103840.0 -9180.0 -0.24 -0.4879 -0.9555 3634969 CHDI2_001647 COc1cc(OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L07 compound treatment 80840.0 -32300.0 -1.0 90960.0 -22100.0 -0.57 -1.1137 -0.9649 3634971 CHDI2_001648 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L08 compound treatment 89760.0 -23400.0 -0.73 99280.0 -13700.0 -0.36 -0.7654 -0.9466 3634973 CHDI2_001649 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccc(COc3ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc3)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L09 compound treatment 8560.0 -105000.0 -3.24 10760.0 -102000.0 -2.66 -4.1708 -0.9951 3634975 CHDI2_001650 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L10 compound treatment 88760.0 -24400.0 -0.76 97000.0 -16000.0 -0.42 -0.8292 -0.9604 3634977 CHDI2_001651 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2cccc(COc3ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc3)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L11 compound treatment 7240.0 -106000.0 -3.28 8280.0 -105000.0 -2.72 -4.2453 -0.9957 3634979 CHDI2_001652 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L12 compound treatment 96040.0 -17100.0 -0.53 92240.0 -20800.0 -0.54 -0.7572 -1.0 3634981 CHDI2_001653 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2COc3ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc3)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L13 compound treatment 7720.0 -105000.0 -3.27 8960.0 -104000.0 -2.7 -4.2223 -0.9956 3634983 CHDI2_001654 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L14 compound treatment 94320.0 -18900.0 -0.58 93200.0 -19800.0 -0.51 -0.7772 -0.998 3634985 CHDI2_001655 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2c3ccccc3COc4ccc(\C=N\NC(=O)CCCCCC(=O)NO)cc4)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L15 compound treatment 66120.0 -47100.0 -1.46 86120.0 -26900.0 -0.7 -1.5251 -0.9433 3634987 CHDI2_001656 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L16 compound treatment 69960.0 -43200.0 -1.34 85160.0 -27900.0 -0.72 -1.4586 -0.9583 3634989 CHDI2_001657 ONC(=O)CCCCCC(=O)N/N=C/c1ccc(O)c(\C=N\NC(=O)CCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L17 compound treatment 69880.0 -43300.0 -1.34 86280.0 -26700.0 -0.69 -1.4398 -0.9531 3634991 CHDI2_001658 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L18 compound treatment 90600.0 -22600.0 -0.7 90560.0 -22500.0 -0.58 -0.9072 -0.9959 3634993 CHDI2_001659 Cc1cc(/C=N/NC(=O)CCCCC(=O)NO)c(O)c(/C=N/NC(=O)CCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L19 compound treatment 93640.0 -19500.0 -0.61 97080.0 -15900.0 -0.41 -0.7208 -0.9829 3634995 CHDI2_001660 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L20 compound treatment 90400.0 -22800.0 -0.71 96120.0 -16900.0 -0.44 -0.8094 -0.9739 3634997 CHDI2_001661 ONC(=O)CCCCC(=O)N/N=C/c1ccc(\C=N\NC(=O)CCCCC(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L21 compound treatment 72680.0 -40500.0 -1.25 78480.0 -34500.0 -0.9 -1.5218 -0.9865 3634999 CHDI2_001662 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)CCCCCCC(=O)Nc4ccccc4O)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L22 compound treatment 93280.0 -19900.0 -0.62 94040.0 -19000.0 -0.49 -0.7846 -0.9939 3635001 CHDI2_001663 COc1cc(/C=N/NC(=O)CCCCC(=O)NO)cc(OC)c1OCCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L23 mock treatment 117640.0 4460.0 0.14 116320.0 3300.0 0.09 0.1585 0.9736 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 L24 mock treatment 97600.0 -15600.0 -0.48 123840.0 10800.0 0.28 -0.1424 -0.255 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M01 compound treatment 33400.0 -79800.0 -2.47 30560.0 -82500.0 -2.14 -3.2628 -0.9975 3554166 CHDI2_001664 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M02 compound treatment 154200.0 41000.0 1.27 120600.0 7580.0 0.2 1.0381 0.8071 3635003 CHDI2_001665 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M03 compound treatment 94640.0 -18500.0 -0.57 109680.0 -3340.0 -0.09 -0.4674 -0.8048 1922299 CHDI2_001666 Oc1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M04 compound treatment 120640.0 7460.0 0.23 118040.0 5020.0 0.13 0.2558 0.9633 3635005 CHDI2_001667 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M05 compound treatment 95320.0 -17900.0 -0.55 104120.0 -8900.0 -0.23 -0.5547 -0.9251 3552393 CHDI2_001668 Oc1ccccc1C(=O)N/N=C/c2ccc(c(F)c2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M06 compound treatment 83120.0 -30100.0 -0.93 120680.0 7660.0 0.2 -0.5177 -0.5436 3635007 CHDI2_001669 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M07 compound treatment 76760.0 -36400.0 -1.13 114520.0 1500.0 0.04 -0.7702 -0.6822 3552669 CHDI2_001670 Oc1ccc(/C=N/NC(=O)c2ccccn2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M08 compound treatment 93400.0 -19800.0 -0.61 101400.0 -11600.0 -0.3 -0.6467 -0.9468 3635009 CHDI2_001671 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M09 compound treatment 7680.0 -105000.0 -3.27 8880.0 -104000.0 -2.71 -4.2246 -0.9956 3635011 CHDI2_001672 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)c2ccccc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M10 compound treatment 92480.0 -20700.0 -0.64 96400.0 -16600.0 -0.43 -0.7587 -0.9815 3635012 CHDI2_001673 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M11 compound treatment 7040.0 -106000.0 -3.29 8160.0 -105000.0 -2.72 -4.2519 -0.9956 3635014 CHDI2_001674 ONC(=O)/C=C/c1ccc(CNCCC2=C[N]c3ccccc23)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M12 compound treatment 84960.0 -28200.0 -0.87 88320.0 -24700.0 -0.64 -1.0719 -0.9884 3635016 CHDI2_001675 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M13 compound treatment 93520.0 -19700.0 -0.61 86600.0 -26400.0 -0.69 -0.916 -0.9982 3614499 CHDI2_001676 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M14 compound treatment 100120.0 -13100.0 -0.4 94400.0 -18600.0 -0.48 -0.6281 -0.996 3635018 CHDI2_001677 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M15 compound treatment 98440.0 -14700.0 -0.46 103640.0 -9380.0 -0.24 -0.4951 -0.9568 3614451 CHDI2_001678 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M16 compound treatment 89760.0 -23400.0 -0.73 102360.0 -10700.0 -0.28 -0.7088 -0.9128 3635020 CHDI2_001679 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M17 compound treatment 92640.0 -20500.0 -0.64 104560.0 -8460.0 -0.22 -0.6053 -0.8992 3614488 CHDI2_001680 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M18 compound treatment 91040.0 -22100.0 -0.69 102680.0 -10300.0 -0.27 -0.6749 -0.9163 3635022 CHDI2_001681 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M19 compound treatment 6760.0 -106000.0 -3.3 8760.0 -104000.0 -2.71 -4.247 -0.9952 3614396 CHDI2_001682 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M20 compound treatment 94480.0 -18700.0 -0.58 102960.0 -10100.0 -0.26 -0.5944 -0.9353 3635024 CHDI2_001683 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M21 compound treatment 77920.0 -35300.0 -1.09 78840.0 -34200.0 -0.89 -1.4003 -0.9947 3614688 CHDI2_001684 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M22 compound treatment 94040.0 -19100.0 -0.59 99360.0 -13700.0 -0.35 -0.6702 -0.9699 3635026 CHDI2_001685 ONC(=O)c1cccc(c1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4cccc(c4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M23 mock treatment 125640.0 12500.0 0.39 116800.0 3780.0 0.1 0.3426 0.8596 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 M24 mock treatment 105200.0 -7980.0 -0.25 132280.0 19300.0 0.5 0.1792 0.321 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N01 compound treatment 102120.0 -11100.0 -0.34 111080.0 -1940.0 -0.05 -0.2778 -0.8024 3635028 CHDI2_001686 Cc1cc(/C=N/NC(=O)CCCCC(=O)Nc2ccccc2O)c(O)c(/C=N/NC(=O)CCCCC(=O)Nc3ccccc3O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N02 compound treatment 139040.0 25900.0 0.8 144800.0 31800.0 0.83 1.1506 0.9999 3635030 CHDI2_001687 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N03 compound treatment 93360.0 -19800.0 -0.61 102200.0 -10800.0 -0.28 -0.6329 -0.9373 3635032 CHDI2_001688 Cc1cc(/C=N/NC(=O)CCCCCC(=O)Nc2ccccc2O)c(O)c(/C=N/NC(=O)CCCCCC(=O)Nc3ccccc3O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N04 compound treatment 96280.0 -16900.0 -0.52 118320.0 5300.0 0.14 -0.2727 -0.5038 3635034 CHDI2_001689 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N05 compound treatment 90120.0 -23100.0 -0.71 101680.0 -11300.0 -0.29 -0.7134 -0.9233 3635036 CHDI2_001690 Cc1cc(/C=N/NC(=O)CCCCCCC(=O)Nc2ccccc2O)c(O)c(/C=N/NC(=O)CCCCCCC(=O)Nc3ccccc3O)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N06 compound treatment 106960.0 -6220.0 -0.19 116360.0 3340.0 0.09 -0.0748 -0.3539 3635038 CHDI2_001691 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N07 compound treatment 80360.0 -32800.0 -1.02 126000.0 13000.0 0.34 -0.4804 -0.4485 3635040 CHDI2_001692 Oc1ccccc1NC(=O)CCCCC(=O)N/N=C/c2ccc(\C=N\NC(=O)CCCCC(=O)Nc3ccccc3O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N08 compound treatment 93440.0 -19700.0 -0.61 95960.0 -17100.0 -0.44 -0.7458 -0.9875 3635042 CHDI2_001693 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OC\C=C\COc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N09 compound treatment 86320.0 -26900.0 -0.83 97840.0 -15200.0 -0.39 -0.8672 -0.9418 3635044 CHDI2_001694 Oc1ccccc1NC(=O)CCCCCC(=O)N/N=C/c2ccc(\C=N\NC(=O)CCCCCC(=O)Nc3ccccc3O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N10 compound treatment 102920.0 -10300.0 -0.32 107320.0 -5700.0 -0.15 -0.3294 -0.9396 3635046 CHDI2_001695 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N11 compound treatment 90720.0 -22500.0 -0.7 114160.0 1140.0 0.03 -0.471 -0.6763 3635048 CHDI2_001696 Oc1ccccc1NC(=O)CCCCCCC(=O)N/N=C/c2ccc(\C=N\NC(=O)CCCCCCC(=O)Nc3ccccc3O)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N12 compound treatment 91560.0 -21600.0 -0.67 104760.0 -8260.0 -0.21 -0.6253 -0.8891 3635050 CHDI2_001697 CCOc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OCC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N13 compound treatment 6680.0 -106000.0 -3.3 7760.0 -105000.0 -2.73 -4.2671 -0.9956 3635052 CHDI2_001698 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(O)c(\C=N\NC(=O)CCCCCCC(=O)NO)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N14 compound treatment 37480.0 -75700.0 -2.35 57560.0 -55500.0 -1.44 -2.6773 -0.9726 3635054 CHDI2_001699 COc1cc(OC/C=C/COc2cc(OC)c(\C=N\NC(=O)CCCCCCC(=O)NO)c(OC)c2)cc(OC)c1\C=N\NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N15 compound treatment 6240.0 -107000.0 -3.31 8400.0 -105000.0 -2.72 -4.265 -0.9952 3635056 CHDI2_001700 COc1cc(/C=N/NC(=O)CCCCCC(=O)NO)cc(OC)c1OCCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N16 compound treatment 84560.0 -28600.0 -0.89 100920.0 -12100.0 -0.31 -0.8492 -0.9027 3635058 CHDI2_001701 COc1cc(OCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N17 compound treatment 6160.0 -107000.0 -3.32 8120.0 -105000.0 -2.73 -4.2719 -0.9953 3635060 CHDI2_001702 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OCCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N18 compound treatment 75560.0 -37600.0 -1.17 96640.0 -16400.0 -0.43 -1.125 -0.9067 3635062 CHDI2_001703 COc1cc(OCCCCCCOc2cc(OC)c(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)cc(OC)c1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N19 compound treatment 70680.0 -42500.0 -1.32 90320.0 -22700.0 -0.59 -1.3481 -0.9344 3635064 CHDI2_001704 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4o3)CC(O2)c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N20 compound treatment 30920.0 -82300.0 -2.55 29520.0 -83500.0 -2.17 -3.3362 -0.9968 3635065 CHDI2_001705 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OC\C=C\COc2c(OC)cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N21 compound treatment 74520.0 -38700.0 -1.2 86280.0 -26700.0 -0.69 -1.3381 -0.9664 3215593 CHDI2_001706 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N22 compound treatment 32160.0 -81000.0 -2.51 31040.0 -82000.0 -2.13 -3.2811 -0.9967 3635067 CHDI2_001707 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc(OC)c1OCCCCCOc2c(OC)cc(/C=N/NC(=O)CCCCCCC(=O)NO)cc2OC 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N23 mock treatment 106760.0 -6420.0 -0.2 121120.0 8100.0 0.21 0.0083 0.0287 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 N24 mock treatment 105080.0 -8100.0 -0.25 129880.0 16900.0 0.44 0.1324 0.2624 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O01 compound treatment 88080.0 -25100.0 -0.78 96680.0 -16300.0 -0.42 -0.85 -0.9595 3554202 CHDI2_001708 CN(CCO)c1ccc(/C=N/NC(=O)c2ccc(cc2)C(=O)NO)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O02 compound treatment 113520.0 345.0 0.01 118400.0 5380.0 0.14 0.1064 0.7589 3635069 CHDI2_001709 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O03 compound treatment 121680.0 8500.0 0.26 101760.0 -11300.0 -0.29 -0.0205 -0.0521 3552203 CHDI2_001710 Oc1ccccc1C(=O)N/N=C/c2cc(Br)c(O)c(Br)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O04 compound treatment 106240.0 -6940.0 -0.21 104880.0 -8140.0 -0.21 -0.3015 -1.0 3635071 CHDI2_001711 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O05 compound treatment 79400.0 -33800.0 -1.05 106160.0 -6860.0 -0.18 -0.866 -0.8158 3552412 CHDI2_001712 CN(CCO)c1ccc(/C=N/NC(=O)c2ccccc2O)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O06 compound treatment 91960.0 -21200.0 -0.66 98960.0 -14100.0 -0.37 -0.7231 -0.9615 3635073 CHDI2_001713 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OC/C=C/COc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O07 compound treatment 75280.0 -37900.0 -1.17 110920.0 -2100.0 -0.05 -0.8688 -0.7391 3552710 CHDI2_001714 Oc1c(Br)cc(/C=N/NC(=O)c2ccccn2)cc1Br 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O08 compound treatment 61280.0 -51900.0 -1.61 94080.0 -18900.0 -0.49 -1.4849 -0.8831 3635075 CHDI2_001715 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O09 compound treatment 5360.0 -108000.0 -3.34 7200.0 -106000.0 -2.75 -4.3063 -0.9953 3635077 CHDI2_001716 OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O10 compound treatment 73240.0 -39900.0 -1.24 99520.0 -13500.0 -0.35 -1.1229 -0.8731 3635078 CHDI2_001717 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O11 compound treatment 11600.0 -102000.0 -3.15 12760.0 -100000.0 -2.6 -4.0674 -0.9956 3635080 CHDI2_001718 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O12 compound treatment 88240.0 -24900.0 -0.77 100880.0 -12100.0 -0.32 -0.7693 -0.9219 3635081 CHDI2_001719 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O13 compound treatment 84600.0 -28600.0 -0.89 97480.0 -15500.0 -0.4 -0.9115 -0.9367 3614501 CHDI2_001720 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O14 compound treatment 80360.0 -32800.0 -1.02 111000.0 -2020.0 -0.05 -0.756 -0.7426 3635083 CHDI2_001721 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O15 compound treatment 75600.0 -37600.0 -1.16 103160.0 -9860.0 -0.26 -1.0044 -0.8425 3614455 CHDI2_001722 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O16 compound treatment 75200.0 -38000.0 -1.18 100560.0 -12500.0 -0.32 -1.0609 -0.8693 3635085 CHDI2_001723 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O17 compound treatment 47400.0 -65800.0 -2.04 57360.0 -55700.0 -1.45 -2.4637 -0.9859 3614538 CHDI2_001724 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O18 compound treatment 75720.0 -37500.0 -1.16 99800.0 -13200.0 -0.34 -1.0635 -0.8787 3635087 CHDI2_001725 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O19 compound treatment 11600.0 -102000.0 -3.15 13960.0 -99100.0 -2.57 -4.0454 -0.995 3614394 CHDI2_001726 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O20 compound treatment 79920.0 -33300.0 -1.03 86400.0 -26600.0 -0.69 -1.2176 -0.9812 3635089 CHDI2_001727 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O21 compound treatment 65240.0 -47900.0 -1.49 69240.0 -43800.0 -1.14 -1.8545 -0.9913 3614525 CHDI2_001728 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O22 compound treatment 89000.0 -24200.0 -0.75 96720.0 -16300.0 -0.42 -0.8291 -0.9635 3635091 CHDI2_001729 ONC(=O)c1ccc(cc1)C(=O)N/N=C/c2ccc(OCCCCCCCCCCCCOc3ccc(\C=N\NC(=O)c4ccc(cc4)C(=O)NO)cc3)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O23 mock treatment 126560.0 13400.0 0.41 134320.0 21300.0 0.55 0.6846 0.9899 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 O24 mock treatment 108960.0 -4220.0 -0.13 132440.0 19400.0 0.5 0.2645 0.5074 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P01 compound treatment 70760.0 -42400.0 -1.31 58720.0 -54300.0 -1.41 -1.9269 -0.9994 3635093 CHDI2_001730 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccc3)CC(O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P02 compound treatment 46240.0 -66900.0 -2.07 21720.0 -91300.0 -2.37 -3.1439 -0.9978 3635094 CHDI2_001731 COc1cc(OC/C=C/COc2ccc(\C=N\NC(=O)CCCCCCC(=O)NO)c(OC)c2)ccc1\C=N\NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P03 compound treatment 75280.0 -37900.0 -1.17 70600.0 -42400.0 -1.1 -1.6096 -0.9995 3215583 CHDI2_001732 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P04 compound treatment 35960.0 -77200.0 -2.39 39320.0 -73700.0 -1.91 -3.0457 -0.9939 3635096 CHDI2_001733 COc1cc(OCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P05 compound treatment 73520.0 -39700.0 -1.23 97160.0 -15900.0 -0.41 -1.1602 -0.8952 3635098 CHDI2_001734 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P06 compound treatment 45320.0 -67900.0 -2.1 62520.0 -50500.0 -1.31 -2.4144 -0.9742 3635099 CHDI2_001735 COc1cc(OCCCCCCOc2ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P07 compound treatment 55320.0 -57900.0 -1.79 86080.0 -26900.0 -0.7 -1.7625 -0.9159 3635101 CHDI2_001736 CC(C)OCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P08 compound treatment 28840.0 -84300.0 -2.61 45640.0 -67400.0 -1.75 -3.0856 -0.981 3635102 CHDI2_001737 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccc(COc3ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc3)cc2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P09 compound treatment 44600.0 -68600.0 -2.12 65880.0 -47100.0 -1.22 -2.3685 -0.9657 3215599 CHDI2_001738 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P10 compound treatment 16600.0 -96600.0 -2.99 27920.0 -85100.0 -2.21 -3.6794 -0.9889 3635104 CHDI2_001739 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2cccc(COc3ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc3)c2)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P11 compound treatment 2840.0 -110000.0 -3.42 3600.0 -109000.0 -2.84 -4.4277 -0.9958 3635106 CHDI2_001740 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(COc3ccccc3)CC(O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P12 compound treatment 4480.0 -109000.0 -3.37 6000.0 -107000.0 -2.78 -4.3476 -0.9955 3635107 CHDI2_001741 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2COc3ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc3)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P13 compound treatment 3280.0 -110000.0 -3.41 4000.0 -109000.0 -2.83 -4.4107 -0.9958 3635109 CHDI2_001742 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@@H]2O[C@H](CSc3ccncc3)C[C@@H](O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P14 compound treatment 14600.0 -98600.0 -3.05 15160.0 -97900.0 -2.54 -3.9576 -0.9958 3635110 CHDI2_001743 ONC(=O)CCCCCCC(=O)N/N=C/c1ccc(OCc2ccccc2c3ccccc3COc4ccc(\C=N\NC(=O)CCCCCCC(=O)NO)cc4)cc1 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P15 compound treatment 75680.0 -37500.0 -1.16 91240.0 -21800.0 -0.57 -1.2216 -0.9453 3635112 CHDI2_001744 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@H]2O[C@@H](CSc3ccncc3)C[C@H](O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P16 compound treatment 34000.0 -79200.0 -2.45 46080.0 -66900.0 -1.74 -2.9645 -0.9858 3635113 CHDI2_001745 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCc2ccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc3OC)cc2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P17 compound treatment 63920.0 -49300.0 -1.53 89360.0 -23700.0 -0.61 -1.5138 -0.9201 3635115 CHDI2_001746 COCC1CC(OC(O1)c2ccc(cc2)C3OC(COC)CC(O3)c4ccc(NC(=O)CCCCCCC(=O)NO)cc4)c5ccc(NC(=O)CCCCCCC(=O)NO)cc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P18 compound treatment 77880.0 -35300.0 -1.09 101960.0 -11100.0 -0.29 -0.9764 -0.8636 3635116 CHDI2_001747 COc1cc(/C=N/NC(=O)CCCCCCC(=O)NO)ccc1OCc2cccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)cc3OC)c2 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P19 compound treatment 67120.0 -46100.0 -1.43 79240.0 -33800.0 -0.88 -1.6296 -0.9727 3215595 CHDI2_001748 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P20 compound treatment 47200.0 -66000.0 -2.04 42240.0 -70800.0 -1.84 -2.7458 -0.9986 3635118 CHDI2_001749 COc1cc(OCc2ccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c3)cc2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P21 compound treatment 3520.0 -110000.0 -3.4 4360.0 -109000.0 -2.82 -4.3988 -0.9958 3635120 CHDI2_001750 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(Cc3ccccc3)Cc4ccccc4)CC(O2)c5ccccc5 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P22 compound treatment 18640.0 -94500.0 -2.93 12680.0 -100000.0 -2.61 -3.9147 -0.9983 3635121 CHDI2_001751 COc1cc(OCc2cccc(COc3ccc(/C=N/NC(=O)CCCCCCC(=O)NO)c(OC)c3)c2)ccc1/C=N/NC(=O)CCCCCCC(=O)NO 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P23 mock treatment 96600.0 -16600.0 -0.51 85520.0 -27500.0 -0.71 -0.8684 -0.9869 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.2407 P24 mock treatment 80200.0 -33000.0 -1.02 61920.0 -51100.0 -1.33 -1.6613 -0.9916 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A01 mock treatment 68680.0 -36300.0 -1.13 76520.0 -38000.0 -0.99 -1.4939 -0.9978 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A02 mock treatment 84440.0 -20600.0 -0.64 141160.0 26700.0 0.69 0.039 0.0414 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A03 mock treatment 94800.0 -10200.0 -0.32 172480.0 58000.0 1.51 0.8414 0.5466 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A04 mock treatment 95080.0 -9940.0 -0.31 182880.0 68400.0 1.78 1.0386 0.576 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A05 mock treatment 98000.0 -7020.0 -0.22 190960.0 76500.0 1.99 1.251 0.626 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A06 mock treatment 83880.0 -21100.0 -0.65 180040.0 65500.0 1.7 0.741 0.4061 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A07 mock treatment 74400.0 -30600.0 -0.95 160320.0 45800.0 1.19 0.171 0.1123 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A08 mock treatment 79120.0 -25900.0 -0.8 177200.0 62700.0 1.63 0.5846 0.3219 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A09 mock treatment 82560.0 -22500.0 -0.7 189760.0 75300.0 1.96 0.8907 0.4291 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A10 mock treatment 76560.0 -28500.0 -0.88 180480.0 66000.0 1.71 0.5887 0.3054 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A11 mock treatment 89040.0 -16000.0 -0.5 159640.0 45100.0 1.17 0.4793 0.3765 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A12 mock treatment 100200.0 -4820.0 -0.15 163600.0 49100.0 1.28 0.7965 0.6201 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A13 mock treatment 88640.0 -16400.0 -0.51 174520.0 60000.0 1.56 0.7439 0.4536 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A14 mock treatment 107160.0 2140.0 0.07 170120.0 55600.0 1.45 1.0688 0.7388 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A15 mock treatment 101680.0 -3340.0 -0.1 165600.0 51100.0 1.33 0.8657 0.65 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A16 mock treatment 81240.0 -23800.0 -0.74 181920.0 67400.0 1.75 0.7177 0.3777 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A17 mock treatment 91960.0 -13100.0 -0.4 167480.0 53000.0 1.38 0.6873 0.479 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A18 mock treatment 97560.0 -7460.0 -0.23 166400.0 51900.0 1.35 0.7901 0.5775 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A19 mock treatment 108440.0 3420.0 0.11 176760.0 62300.0 1.62 1.2188 0.7518 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A20 mock treatment 125840.0 20800.0 0.65 194680.0 80200.0 2.08 1.9293 0.8846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A21 mock treatment 112640.0 7620.0 0.24 192600.0 78100.0 2.03 1.6019 0.7841 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A22 mock treatment 113160.0 8140.0 0.25 152120.0 37600.0 0.98 0.8696 0.8614 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A23 mock treatment 95400.0 -9620.0 -0.3 121840.0 7340.0 0.19 -0.0759 -0.2144 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base A24 mock treatment 69400.0 -35600.0 -1.1 73760.0 -40700.0 -1.06 -1.5289 -0.9998 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B01 mock treatment 143080.0 38100.0 1.18 148400.0 33900.0 0.88 1.4567 0.9897 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B02 mock treatment 145320.0 40300.0 1.25 191320.0 76800.0 2.0 2.2944 0.9745 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B03 mock treatment 161280.0 56300.0 1.74 209640.0 95100.0 2.47 2.9806 0.9854 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B04 mock treatment 143440.0 38400.0 1.19 194520.0 80000.0 2.08 2.312 0.965 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B05 mock treatment 158720.0 53700.0 1.66 165760.0 51300.0 1.33 2.1184 0.9939 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B06 mock treatment 138880.0 33900.0 1.05 142040.0 27500.0 0.72 1.2479 0.9826 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B07 mock treatment 98240.0 -6780.0 -0.21 167920.0 53400.0 1.39 0.833 0.5933 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B08 mock treatment 105480.0 461.0 0.01 153800.0 39300.0 1.02 0.7322 0.7169 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B09 mock treatment 124520.0 19500.0 0.6 158840.0 44300.0 1.15 1.2419 0.9546 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B10 mock treatment 108680.0 3660.0 0.11 109560.0 -4940.0 -0.13 -0.0105 -0.0615 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B11 mock treatment 124240.0 19200.0 0.6 133600.0 19100.0 0.5 0.7721 0.9959 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B12 mock treatment 136680.0 31700.0 0.98 147120.0 32600.0 0.85 1.293 0.9973 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B13 mock treatment 164120.0 59100.0 1.83 158640.0 44100.0 1.15 2.1058 0.9746 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B14 mock treatment 176760.0 71700.0 2.22 171920.0 57400.0 1.49 2.6268 0.9812 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B15 mock treatment 121600.0 16600.0 0.51 135720.0 21200.0 0.55 0.7532 0.9994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B16 mock treatment 112920.0 7900.0 0.24 128520.0 14000.0 0.36 0.4307 0.9813 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B17 mock treatment 104920.0 -98.9 0.0 168240.0 53700.0 1.4 0.9852 0.7056 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B18 mock treatment 145360.0 40300.0 1.25 182000.0 67500.0 1.75 2.124 0.9862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B19 mock treatment 135320.0 30300.0 0.94 187520.0 73000.0 1.9 2.0055 0.9474 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B20 mock treatment 160880.0 55900.0 1.73 173560.0 59100.0 1.53 2.309 0.9982 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B21 mock treatment 126920.0 21900.0 0.68 185480.0 71000.0 1.84 1.7839 0.9078 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B22 mock treatment 152000.0 47000.0 1.46 203200.0 88700.0 2.3 2.659 0.9754 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B23 mock treatment 131280.0 26300.0 0.81 184520.0 70000.0 1.82 1.8618 0.9342 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base B24 mock treatment 108120.0 3100.0 0.1 129160.0 14700.0 0.38 0.3373 0.8586 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C01 mock treatment 84720.0 -20300.0 -0.63 135560.0 21100.0 0.55 -0.0578 -0.0693 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C02 mock treatment 108960.0 3940.0 0.12 206120.0 91600.0 2.38 1.7697 0.7424 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C03 mock treatment 114760.0 9740.0 0.3 182440.0 67900.0 1.77 1.4617 0.8162 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C04 mock treatment 119160.0 14100.0 0.44 188880.0 74400.0 1.93 1.6764 0.846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C05 mock treatment 136600.0 31600.0 0.98 166600.0 52100.0 1.35 1.6492 0.9873 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C06 mock treatment 109840.0 4820.0 0.15 163080.0 48600.0 1.26 0.9982 0.7853 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C07 mock treatment 119600.0 14600.0 0.45 119640.0 5140.0 0.13 0.4139 0.8786 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C08 mock treatment 107480.0 2460.0 0.08 114240.0 -259.0 -0.01 0.0492 0.6422 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C09 mock treatment 111360.0 6340.0 0.2 120560.0 6060.0 0.16 0.2503 0.994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C10 mock treatment 100800.0 -4220.0 -0.13 127880.0 13400.0 0.35 0.1534 0.413 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C11 mock treatment 99680.0 -5340.0 -0.17 136360.0 21900.0 0.57 0.2847 0.4812 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C12 mock treatment 127760.0 22700.0 0.7 186360.0 71900.0 1.87 1.8185 0.9112 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C13 mock treatment 148560.0 43500.0 1.35 155840.0 41300.0 1.07 1.7135 0.9936 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C14 mock treatment 136560.0 31500.0 0.98 161160.0 46700.0 1.21 1.5483 0.9943 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C15 mock treatment 114800.0 9780.0 0.3 169040.0 54500.0 1.42 1.2164 0.8393 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C16 mock treatment 101000.0 -4020.0 -0.12 157000.0 42500.0 1.1 0.6928 0.6234 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C17 mock treatment 95520.0 -9500.0 -0.29 162440.0 47900.0 1.25 0.6727 0.5256 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C18 mock treatment 107920.0 2900.0 0.09 170560.0 56100.0 1.46 1.0935 0.7493 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C19 mock treatment 131800.0 26800.0 0.83 122360.0 7860.0 0.2 0.7312 0.8556 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C20 mock treatment 129560.0 24500.0 0.76 193560.0 79100.0 2.05 1.9902 0.9086 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C21 mock treatment 140720.0 35700.0 1.11 154600.0 40100.0 1.04 1.5189 0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C22 mock treatment 128640.0 23600.0 0.73 199680.0 85200.0 2.21 2.0825 0.8934 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C23 mock treatment 130160.0 25100.0 0.78 194920.0 80400.0 2.09 2.0284 0.9096 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base C24 mock treatment 105080.0 61.1 0.0 153720.0 39200.0 1.02 0.7219 0.7084 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D01 mock treatment 122400.0 17400.0 0.54 168200.0 53700.0 1.4 1.3674 0.9143 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D02 mock treatment 122120.0 17100.0 0.53 137920.0 23400.0 0.61 0.805 0.9976 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D03 mock treatment 125080.0 20100.0 0.62 138040.0 23500.0 0.61 0.872 1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D04 mock treatment 143800.0 38800.0 1.2 122880.0 8380.0 0.22 1.0036 0.8219 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D05 mock treatment 119960.0 14900.0 0.46 157360.0 42900.0 1.11 1.1148 0.9244 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D06 mock treatment 118480.0 13500.0 0.42 124440.0 9940.0 0.26 0.4776 0.9735 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D07 mock treatment 112640.0 7620.0 0.24 112400.0 -2100.0 -0.05 0.1284 0.5298 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D08 mock treatment 132760.0 27700.0 0.86 119640.0 5140.0 0.13 0.7022 0.8073 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D09 mock treatment 122280.0 17300.0 0.53 104880.0 -9620.0 -0.25 0.2015 0.3412 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D10 mock treatment 124480.0 19500.0 0.6 120080.0 5580.0 0.15 0.5289 0.8528 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D11 mock treatment 121000.0 16000.0 0.5 122360.0 7860.0 0.2 0.4946 0.9233 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D12 mock treatment 116920.0 11900.0 0.37 122480.0 7980.0 0.21 0.4074 0.9629 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D13 mock treatment 113600.0 8580.0 0.27 93080.0 -21400.0 -0.56 -0.2055 -0.3332 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D14 mock treatment 115400.0 10400.0 0.32 124880.0 10400.0 0.27 0.4182 0.9962 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D15 mock treatment 108960.0 3940.0 0.12 116640.0 2140.0 0.06 0.1257 0.9366 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D16 mock treatment 111280.0 6260.0 0.19 129320.0 14800.0 0.39 0.4095 0.9496 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D17 mock treatment 119320.0 14300.0 0.44 114240.0 -259.0 -0.01 0.3086 0.6963 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D18 mock treatment 114160.0 9140.0 0.28 117480.0 2980.0 0.08 0.255 0.8686 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D19 mock treatment 131400.0 26400.0 0.82 138600.0 24100.0 0.63 1.0208 0.9913 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D20 mock treatment 109240.0 4220.0 0.13 122560.0 8060.0 0.21 0.2406 0.9743 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D21 mock treatment 109200.0 4180.0 0.13 134920.0 20400.0 0.53 0.4668 0.8546 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D22 mock treatment 113080.0 8060.0 0.25 127480.0 13000.0 0.34 0.4151 0.9891 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D23 mock treatment 124960.0 19900.0 0.62 136440.0 21900.0 0.57 0.84 0.9992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base D24 mock treatment 92440.0 -12600.0 -0.39 119480.0 4980.0 0.13 -0.1841 -0.4482 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E01 mock treatment 82800.0 -22200.0 -0.69 157680.0 43200.0 1.12 0.3065 0.2329 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E02 mock treatment 102760.0 -2260.0 -0.07 175240.0 60700.0 1.58 1.0665 0.6751 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E03 mock treatment 95480.0 -9540.0 -0.3 158920.0 44400.0 1.15 0.6071 0.5096 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E04 mock treatment 101000.0 -4020.0 -0.12 168880.0 54400.0 1.41 0.9111 0.6423 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E05 mock treatment 105840.0 821.0 0.03 116640.0 2140.0 0.06 0.0573 0.9371 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E06 mock treatment 110800.0 5780.0 0.18 125560.0 11100.0 0.29 0.3299 0.9741 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E07 mock treatment 96160.0 -8860.0 -0.27 104480.0 -10000.0 -0.26 -0.3782 -0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E08 mock treatment 93360.0 -11700.0 -0.36 109120.0 -5380.0 -0.14 -0.3543 -0.9146 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E09 mock treatment 94840.0 -10200.0 -0.32 118720.0 4220.0 0.11 -0.1455 -0.4356 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E10 mock treatment 106400.0 1380.0 0.04 104040.0 -10500.0 -0.27 -0.1619 -0.5885 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E11 mock treatment 103800.0 -1220.0 -0.04 109040.0 -5460.0 -0.14 -0.127 -0.8652 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E12 mock treatment 107440.0 2420.0 0.08 98640.0 -15900.0 -0.41 -0.2383 -0.569 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E13 mock treatment 115720.0 10700.0 0.33 122760.0 8260.0 0.21 0.3862 0.9778 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E14 mock treatment 109560.0 4540.0 0.14 100000.0 -14500.0 -0.38 -0.1669 -0.415 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E15 mock treatment 109960.0 4940.0 0.15 104640.0 -9860.0 -0.26 -0.0729 -0.2442 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E16 mock treatment 85000.0 -20000.0 -0.62 113360.0 -1140.0 -0.03 -0.4595 -0.74 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E17 mock treatment 95880.0 -9140.0 -0.28 107080.0 -7420.0 -0.19 -0.3365 -0.9824 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E18 mock treatment 107760.0 2740.0 0.08 109200.0 -5300.0 -0.14 -0.0373 -0.2306 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E19 mock treatment 109680.0 4660.0 0.14 118040.0 3540.0 0.09 0.1672 0.9763 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E20 mock treatment 121040.0 16000.0 0.5 118400.0 3900.0 0.1 0.4227 0.8343 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E21 mock treatment 103360.0 -1660.0 -0.05 113360.0 -1140.0 -0.03 -0.0573 -0.9656 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E22 mock treatment 107280.0 2260.0 0.07 142360.0 27900.0 0.72 0.5614 0.7719 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E23 mock treatment 97080.0 -7940.0 -0.25 151280.0 36800.0 0.96 0.5018 0.5085 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base E24 mock treatment 87560.0 -17500.0 -0.54 134240.0 19700.0 0.51 -0.0198 -0.0266 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F01 mock treatment 107080.0 2060.0 0.06 175120.0 60600.0 1.58 1.1589 0.7352 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F02 mock treatment 99280.0 -5740.0 -0.18 168520.0 54000.0 1.4 0.8668 0.6126 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F03 mock treatment 111520.0 6500.0 0.2 133160.0 18700.0 0.48 0.4853 0.9243 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F04 mock treatment 120040.0 15000.0 0.47 130680.0 16200.0 0.42 0.6264 0.9987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F05 mock treatment 112240.0 7220.0 0.22 125360.0 10900.0 0.28 0.3578 0.9934 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F06 mock treatment 115680.0 10700.0 0.33 111680.0 -2820.0 -0.07 0.1818 0.5373 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F07 mock treatment 111960.0 6940.0 0.22 105160.0 -9340.0 -0.24 -0.0195 -0.0602 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F08 mock treatment 116240.0 11200.0 0.35 105920.0 -8580.0 -0.22 0.0882 0.2136 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F09 mock treatment 106480.0 1460.0 0.05 97920.0 -16600.0 -0.43 -0.2726 -0.6293 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F10 mock treatment 113720.0 8700.0 0.27 103840.0 -10700.0 -0.28 -0.0052 -0.0135 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F11 mock treatment 115880.0 10900.0 0.34 115160.0 661.0 0.02 0.2501 0.7422 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F12 mock treatment 118440.0 13400.0 0.42 103040.0 -11500.0 -0.3 0.0835 0.1633 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F13 mock treatment 113680.0 8660.0 0.27 103840.0 -10700.0 -0.28 -0.0061 -0.0158 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F14 mock treatment 119000.0 14000.0 0.43 106000.0 -8500.0 -0.22 0.1502 0.3088 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F15 mock treatment 111040.0 6020.0 0.19 110840.0 -3660.0 -0.1 0.0647 0.3089 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F16 mock treatment 104560.0 -459.0 -0.01 112480.0 -2020.0 -0.05 -0.0472 -0.8675 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F17 mock treatment 120680.0 15700.0 0.49 111000.0 -3500.0 -0.09 0.2788 0.5648 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F18 mock treatment 107720.0 2700.0 0.08 102120.0 -12400.0 -0.32 -0.1683 -0.5063 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F19 mock treatment 113240.0 8220.0 0.25 112120.0 -2380.0 -0.06 0.1364 0.5204 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F20 mock treatment 111280.0 6260.0 0.19 124440.0 9940.0 0.26 0.3198 0.99 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F21 mock treatment 106920.0 1900.0 0.06 125440.0 10900.0 0.28 0.2427 0.8359 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F22 mock treatment 102920.0 -2100.0 -0.07 114840.0 341.0 0.01 -0.0397 -0.6052 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F23 mock treatment 117440.0 12400.0 0.38 142320.0 27800.0 0.72 0.7833 0.9565 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base F24 mock treatment 89680.0 -15300.0 -0.48 143000.0 28500.0 0.74 0.1876 0.2132 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G01 mock treatment 99280.0 -5740.0 -0.18 148560.0 34100.0 0.88 0.5001 0.554 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G02 mock treatment 84760.0 -20300.0 -0.63 160600.0 46100.0 1.2 0.4031 0.2981 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G03 mock treatment 105840.0 821.0 0.03 122200.0 7700.0 0.2 0.1595 0.7907 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G04 mock treatment 100960.0 -4060.0 -0.13 122120.0 7620.0 0.2 0.0511 0.2178 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G05 mock treatment 101080.0 -3940.0 -0.12 103160.0 -11300.0 -0.29 -0.2946 -0.9239 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G06 mock treatment 100640.0 -4380.0 -0.14 113560.0 -939.0 -0.02 -0.1132 -0.8211 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G07 mock treatment 106160.0 1140.0 0.04 104680.0 -9820.0 -0.26 -0.1554 -0.6033 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G08 mock treatment 98480.0 -6540.0 -0.2 110560.0 -3940.0 -0.1 -0.2156 -0.95 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G09 mock treatment 104920.0 -98.9 0.0 95400.0 -19100.0 -0.5 -0.3531 -0.7115 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G10 mock treatment 109960.0 4940.0 0.15 98440.0 -16100.0 -0.42 -0.1868 -0.4203 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G11 mock treatment 107400.0 2380.0 0.07 105800.0 -8700.0 -0.23 -0.1077 -0.4528 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G12 mock treatment 108080.0 3060.0 0.09 103760.0 -10700.0 -0.28 -0.1302 -0.4419 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G13 mock treatment 106760.0 1740.0 0.05 88160.0 -26300.0 -0.68 -0.4458 -0.6494 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G14 mock treatment 105920.0 901.0 0.03 96920.0 -17600.0 -0.46 -0.3032 -0.6626 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G15 mock treatment 110880.0 5860.0 0.18 97480.0 -17000.0 -0.44 -0.1843 -0.3855 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G16 mock treatment 103480.0 -1540.0 -0.05 127280.0 12800.0 0.33 0.2011 0.5994 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G17 mock treatment 101200.0 -3820.0 -0.12 108120.0 -6380.0 -0.17 -0.2009 -0.9864 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G18 mock treatment 111640.0 6620.0 0.21 101120.0 -13400.0 -0.35 -0.1007 -0.2496 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G19 mock treatment 102560.0 -2460.0 -0.08 113120.0 -1380.0 -0.04 -0.0792 -0.9408 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G20 mock treatment 116240.0 11200.0 0.35 101840.0 -12700.0 -0.33 0.0133 0.0277 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G21 mock treatment 114560.0 9540.0 0.3 119040.0 4540.0 0.12 0.2925 0.9188 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G22 mock treatment 103920.0 -1100.0 -0.03 108720.0 -5780.0 -0.15 -0.1303 -0.846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G23 mock treatment 100440.0 -4580.0 -0.14 122840.0 8340.0 0.22 0.0529 0.2043 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base G24 mock treatment 103840.0 -1180.0 -0.04 114880.0 381.0 0.01 -0.0188 -0.4976 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H01 mock treatment 121120.0 16100.0 0.5 154080.0 39600.0 1.03 1.08 0.9448 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H02 mock treatment 104240.0 -779.0 -0.02 131040.0 16500.0 0.43 0.2868 0.6664 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H03 mock treatment 113280.0 8260.0 0.26 117440.0 2940.0 0.08 0.235 0.8798 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H04 mock treatment 103080.0 -1940.0 -0.06 129120.0 14600.0 0.38 0.2261 0.588 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H05 mock treatment 118800.0 13800.0 0.43 115240.0 741.0 0.02 0.3155 0.7382 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H06 mock treatment 111120.0 6100.0 0.19 126160.0 11700.0 0.3 0.3479 0.9742 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H07 mock treatment 109840.0 4820.0 0.15 120720.0 6220.0 0.16 0.2199 0.9992 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H08 mock treatment 115280.0 10300.0 0.32 111000.0 -3500.0 -0.09 0.1605 0.4854 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H09 mock treatment 111360.0 6340.0 0.2 111760.0 -2740.0 -0.07 0.0886 0.424 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H10 mock treatment 108560.0 3540.0 0.11 107680.0 -6820.0 -0.18 -0.0477 -0.2289 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H11 mock treatment 109080.0 4060.0 0.13 103200.0 -11300.0 -0.29 -0.1186 -0.3714 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H12 mock treatment 103080.0 -1940.0 -0.06 109080.0 -5420.0 -0.14 -0.142 -0.9279 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H13 mock treatment 114680.0 9660.0 0.3 106040.0 -8460.0 -0.22 0.0563 0.1515 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H14 mock treatment 104000.0 -1020.0 -0.03 102840.0 -11700.0 -0.3 -0.2365 -0.7766 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H15 mock treatment 103080.0 -1940.0 -0.06 100560.0 -13900.0 -0.36 -0.2986 -0.8133 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H16 mock treatment 111720.0 6700.0 0.21 116200.0 1700.0 0.04 0.1781 0.8388 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H17 mock treatment 113080.0 8060.0 0.25 114440.0 -59.2 0.0 0.1755 0.7027 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H18 mock treatment 105160.0 141.0 0.0 109720.0 -4780.0 -0.12 -0.0847 -0.6818 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H19 mock treatment 106800.0 1780.0 0.06 111760.0 -2740.0 -0.07 -0.0113 -0.1255 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H20 mock treatment 107200.0 2180.0 0.07 103960.0 -10500.0 -0.27 -0.1458 -0.5171 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H21 mock treatment 101960.0 -3060.0 -0.09 107920.0 -6580.0 -0.17 -0.1879 -0.9613 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H22 mock treatment 110480.0 5460.0 0.17 108160.0 -6340.0 -0.16 0.0032 0.0135 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H23 mock treatment 103080.0 -1940.0 -0.06 129400.0 14900.0 0.39 0.2313 0.5903 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base H24 mock treatment 77160.0 -27900.0 -0.86 114200.0 -299.0 -0.01 -0.6159 -0.7134 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I01 mock treatment 97720.0 -7300.0 -0.23 126680.0 12200.0 0.32 0.0639 0.1642 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I02 mock treatment 101480.0 -3540.0 -0.11 148360.0 33900.0 0.88 0.5446 0.6142 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I03 mock treatment 94600.0 -10400.0 -0.32 118040.0 3540.0 0.09 -0.1632 -0.4862 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I04 mock treatment 106080.0 1060.0 0.03 108880.0 -5620.0 -0.15 -0.08 -0.5345 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I05 mock treatment 100000.0 -5020.0 -0.16 105080.0 -9420.0 -0.24 -0.283 -0.976 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I06 mock treatment 102280.0 -2740.0 -0.08 112160.0 -2340.0 -0.06 -0.103 -0.9866 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I07 mock treatment 104080.0 -939.0 -0.03 103320.0 -11200.0 -0.29 -0.226 -0.7741 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I08 mock treatment 107680.0 2660.0 0.08 107720.0 -6780.0 -0.18 -0.0662 -0.3406 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I09 mock treatment 104080.0 -939.0 -0.03 108440.0 -6060.0 -0.16 -0.1319 -0.8238 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I10 mock treatment 104840.0 -179.0 -0.01 102280.0 -12200.0 -0.32 -0.2284 -0.7193 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I11 mock treatment 105600.0 581.0 0.02 105680.0 -8820.0 -0.23 -0.1493 -0.6495 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I12 mock treatment 108680.0 3660.0 0.11 95800.0 -18700.0 -0.49 -0.2633 -0.5278 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I13 mock treatment 102320.0 -2700.0 -0.08 96280.0 -18200.0 -0.47 -0.3939 -0.8193 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I14 mock treatment 103320.0 -1700.0 -0.05 102400.0 -12100.0 -0.31 -0.2595 -0.8142 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I15 mock treatment 103480.0 -1540.0 -0.05 108120.0 -6380.0 -0.17 -0.1509 -0.875 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I16 mock treatment 108800.0 3780.0 0.12 107280.0 -7220.0 -0.19 -0.0498 -0.2252 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I17 mock treatment 114360.0 9340.0 0.29 117400.0 2900.0 0.08 0.258 0.8625 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I18 mock treatment 108040.0 3020.0 0.09 108480.0 -6020.0 -0.16 -0.0444 -0.2436 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I19 mock treatment 111320.0 6300.0 0.2 139680.0 25200.0 0.65 0.6007 0.8798 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I20 mock treatment 103120.0 -1900.0 -0.06 140400.0 25900.0 0.67 0.4343 0.6428 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I21 mock treatment 114880.0 9860.0 0.31 130240.0 15700.0 0.41 0.5053 0.9897 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I22 mock treatment 104680.0 -339.0 -0.01 144480.0 30000.0 0.78 0.5434 0.6975 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I23 mock treatment 114800.0 9780.0 0.3 109120.0 -5380.0 -0.14 0.1155 0.346 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base I24 mock treatment 74320.0 -30700.0 -0.95 112760.0 -1740.0 -0.05 -0.7045 -0.7399 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J01 mock treatment 140840.0 35800.0 1.11 112560.0 -1940.0 -0.05 0.7492 0.6743 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J02 mock treatment 108160.0 3140.0 0.1 140480.0 26000.0 0.68 0.5462 0.8008 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J03 mock treatment 105480.0 461.0 0.01 110120.0 -4380.0 -0.11 -0.0704 -0.6135 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J04 mock treatment 103440.0 -1580.0 -0.05 117840.0 3340.0 0.09 0.0268 0.2688 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J05 mock treatment 111800.0 6780.0 0.21 119480.0 4980.0 0.13 0.2401 0.9729 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J06 mock treatment 103480.0 -1540.0 -0.05 108960.0 -5540.0 -0.14 -0.1355 -0.8936 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J07 mock treatment 104680.0 -339.0 -0.01 105520.0 -8980.0 -0.23 -0.1724 -0.7382 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J08 mock treatment 102520.0 -2500.0 -0.08 105520.0 -8980.0 -0.23 -0.2197 -0.8938 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J09 mock treatment 103560.0 -1460.0 -0.05 108880.0 -5620.0 -0.15 -0.1352 -0.8846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J10 mock treatment 103600.0 -1420.0 -0.04 112360.0 -2140.0 -0.06 -0.0704 -0.9933 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J11 mock treatment 96840.0 -8180.0 -0.25 97400.0 -17100.0 -0.44 -0.4934 -0.9646 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J12 mock treatment 105080.0 61.1 0.0 99360.0 -15100.0 -0.39 -0.2768 -0.7037 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J13 mock treatment 102520.0 -2500.0 -0.08 101240.0 -13300.0 -0.34 -0.2984 -0.8449 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J14 mock treatment 106560.0 1540.0 0.05 105280.0 -9220.0 -0.24 -0.1356 -0.5552 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J15 mock treatment 103800.0 -1220.0 -0.04 108560.0 -5940.0 -0.15 -0.1358 -0.8549 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J16 mock treatment 109600.0 4580.0 0.14 106640.0 -7860.0 -0.2 -0.044 -0.177 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J17 mock treatment 105240.0 221.0 0.01 109040.0 -5460.0 -0.14 -0.0955 -0.6722 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J18 mock treatment 96920.0 -8100.0 -0.25 101200.0 -13300.0 -0.35 -0.4218 -0.9877 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J19 mock treatment 107360.0 2340.0 0.07 112800.0 -1700.0 -0.04 0.0201 0.2364 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J20 mock treatment 105120.0 101.0 0.0 109960.0 -4540.0 -0.12 -0.0812 -0.6881 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J21 mock treatment 113160.0 8140.0 0.25 108160.0 -6340.0 -0.16 0.0619 0.2055 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J22 mock treatment 98480.0 -6540.0 -0.2 113880.0 -619.0 -0.02 -0.1546 -0.7609 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J23 mock treatment 108040.0 3020.0 0.09 105400.0 -9100.0 -0.24 -0.101 -0.3971 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base J24 mock treatment 95120.0 -9900.0 -0.31 123720.0 9220.0 0.24 -0.0475 -0.122 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K01 mock treatment 123640.0 18600.0 0.58 106360.0 -8140.0 -0.21 0.2584 0.4206 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K02 mock treatment 94080.0 -10900.0 -0.34 143880.0 29400.0 0.76 0.3001 0.3593 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K03 mock treatment 112480.0 7460.0 0.23 100120.0 -14400.0 -0.37 -0.1007 -0.2292 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K04 mock treatment 109200.0 4180.0 0.13 103880.0 -10600.0 -0.28 -0.1035 -0.3395 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K05 mock treatment 103080.0 -1940.0 -0.06 109760.0 -4740.0 -0.12 -0.1296 -0.9456 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K06 mock treatment 101080.0 -3940.0 -0.12 108400.0 -6100.0 -0.16 -0.1984 -0.9917 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K07 mock treatment 99920.0 -5100.0 -0.16 102480.0 -12000.0 -0.31 -0.3325 -0.9502 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K08 mock treatment 97880.0 -7140.0 -0.22 104960.0 -9540.0 -0.25 -0.3317 -0.9984 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K09 mock treatment 104240.0 -779.0 -0.02 100680.0 -13800.0 -0.36 -0.271 -0.7529 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K10 mock treatment 101880.0 -3140.0 -0.1 100480.0 -14000.0 -0.36 -0.3263 -0.8656 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K11 mock treatment 107200.0 2180.0 0.07 108080.0 -6420.0 -0.17 -0.0702 -0.3898 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K12 mock treatment 96560.0 -8460.0 -0.26 97760.0 -16700.0 -0.43 -0.4929 -0.9706 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K13 mock treatment 100120.0 -4900.0 -0.15 105640.0 -8860.0 -0.23 -0.2701 -0.9796 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K14 mock treatment 100000.0 -5020.0 -0.16 104960.0 -9540.0 -0.25 -0.2852 -0.9748 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K15 mock treatment 104920.0 -98.9 0.0 117560.0 3060.0 0.08 0.0541 0.6794 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K16 mock treatment 101880.0 -3140.0 -0.1 101480.0 -13000.0 -0.34 -0.308 -0.875 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K17 mock treatment 107040.0 2020.0 0.06 97960.0 -16500.0 -0.43 -0.2596 -0.5978 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K18 mock treatment 96680.0 -8340.0 -0.26 104440.0 -10100.0 -0.26 -0.3675 -1.0 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K19 mock treatment 111440.0 6420.0 0.2 118360.0 3860.0 0.1 0.2116 0.9497 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K20 mock treatment 116600.0 11600.0 0.36 107600.0 -6900.0 -0.18 0.127 0.3166 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K21 mock treatment 104280.0 -739.0 -0.02 98880.0 -15600.0 -0.41 -0.3032 -0.7458 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K22 mock treatment 99760.0 -5260.0 -0.16 102840.0 -11700.0 -0.3 -0.3294 -0.9577 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K23 mock treatment 104760.0 -259.0 -0.01 113040.0 -1460.0 -0.04 -0.0325 -0.8382 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base K24 mock treatment 110160.0 5140.0 0.16 97320.0 -17200.0 -0.45 -0.203 -0.4283 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L01 mock treatment 130040.0 25000.0 0.78 101200.0 -13300.0 -0.35 0.3039 0.358 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L02 mock treatment 107120.0 2100.0 0.07 144080.0 29600.0 0.77 0.5895 0.7643 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L03 mock treatment 109520.0 4500.0 0.14 96480.0 -18000.0 -0.47 -0.2324 -0.4758 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L04 mock treatment 105400.0 381.0 0.01 114880.0 381.0 0.01 0.0153 0.9961 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L05 mock treatment 100320.0 -4700.0 -0.15 111200.0 -3300.0 -0.09 -0.1636 -0.9681 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L06 mock treatment 96840.0 -8180.0 -0.25 117400.0 2900.0 0.08 -0.1259 -0.4762 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L07 mock treatment 96760.0 -8260.0 -0.26 103000.0 -11500.0 -0.3 -0.3922 -0.997 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L08 mock treatment 96520.0 -8500.0 -0.26 108240.0 -6260.0 -0.16 -0.3012 -0.9732 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L09 mock treatment 101440.0 -3580.0 -0.11 101400.0 -13100.0 -0.34 -0.3191 -0.8914 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L10 mock treatment 101440.0 -3580.0 -0.11 104960.0 -9540.0 -0.25 -0.2537 -0.9342 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L11 mock treatment 94560.0 -10500.0 -0.32 93800.0 -20700.0 -0.54 -0.6094 -0.9706 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L12 mock treatment 102800.0 -2220.0 -0.07 94800.0 -19700.0 -0.51 -0.4105 -0.7949 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L13 mock treatment 98280.0 -6740.0 -0.21 89880.0 -24600.0 -0.64 -0.6 -0.8916 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L14 mock treatment 99560.0 -5460.0 -0.17 107200.0 -7300.0 -0.19 -0.2537 -0.9984 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L15 mock treatment 91120.0 -13900.0 -0.43 100560.0 -13900.0 -0.36 -0.5606 -0.9963 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L16 mock treatment 98520.0 -6500.0 -0.2 99640.0 -14900.0 -0.39 -0.4154 -0.954 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L17 mock treatment 100880.0 -4140.0 -0.13 98560.0 -15900.0 -0.41 -0.3835 -0.8846 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L18 mock treatment 92080.0 -12900.0 -0.4 101120.0 -13400.0 -0.35 -0.5293 -0.9975 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L19 mock treatment 114680.0 9660.0 0.3 105000.0 -9500.0 -0.25 0.0371 0.0957 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L20 mock treatment 95120.0 -9900.0 -0.31 105200.0 -9300.0 -0.24 -0.3877 -0.993 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L21 mock treatment 105680.0 661.0 0.02 109120.0 -5380.0 -0.14 -0.0843 -0.5971 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L22 mock treatment 100520.0 -4500.0 -0.14 105120.0 -9380.0 -0.24 -0.2709 -0.9649 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L23 mock treatment 104000.0 -1020.0 -0.03 102080.0 -12400.0 -0.32 -0.2505 -0.7726 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base L24 mock treatment 98920.0 -6100.0 -0.19 98120.0 -16400.0 -0.43 -0.4346 -0.9332 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M01 mock treatment 74760.0 -30300.0 -0.94 90720.0 -23800.0 -0.62 -1.0998 -0.9795 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M02 mock treatment 87360.0 -17700.0 -0.55 148120.0 33600.0 0.87 0.2308 0.2239 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M03 mock treatment 101760.0 -3260.0 -0.1 106720.0 -7780.0 -0.2 -0.2143 -0.9486 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M04 mock treatment 99400.0 -5620.0 -0.17 92760.0 -21700.0 -0.56 -0.5225 -0.884 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M05 mock treatment 95080.0 -9940.0 -0.31 99800.0 -14700.0 -0.38 -0.4878 -0.9943 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M06 mock treatment 100240.0 -4780.0 -0.15 98200.0 -16300.0 -0.42 -0.4042 -0.9009 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M07 mock treatment 103880.0 -1140.0 -0.04 92440.0 -22100.0 -0.57 -0.4302 -0.7492 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M08 mock treatment 97920.0 -7100.0 -0.22 91240.0 -23300.0 -0.6 -0.5829 -0.9063 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M09 mock treatment 98280.0 -6740.0 -0.21 98280.0 -16200.0 -0.42 -0.4456 -0.9475 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M10 mock treatment 104920.0 -98.9 0.0 103640.0 -10900.0 -0.28 -0.2017 -0.7147 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M11 mock treatment 104120.0 -899.0 -0.03 109200.0 -5300.0 -0.14 -0.1171 -0.8333 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M12 mock treatment 104560.0 -459.0 -0.01 115360.0 861.0 0.02 0.0058 0.2174 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M13 mock treatment 93720.0 -11300.0 -0.35 95720.0 -18800.0 -0.49 -0.5926 -0.9867 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M14 mock treatment 103000.0 -2020.0 -0.06 100640.0 -13900.0 -0.36 -0.2989 -0.8177 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M15 mock treatment 101640.0 -3380.0 -0.1 97680.0 -16800.0 -0.44 -0.383 -0.8524 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M16 mock treatment 96240.0 -8780.0 -0.27 97240.0 -17300.0 -0.45 -0.5094 -0.9713 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M17 mock treatment 90800.0 -14200.0 -0.44 108600.0 -5900.0 -0.15 -0.4199 -0.9002 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M18 mock treatment 105160.0 141.0 0.0 98200.0 -16300.0 -0.42 -0.2964 -0.6998 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M19 mock treatment 100840.0 -4180.0 -0.13 105040.0 -9460.0 -0.25 -0.2653 -0.9552 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M20 mock treatment 111200.0 6180.0 0.19 101040.0 -13500.0 -0.35 -0.1119 -0.2805 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M21 mock treatment 99160.0 -5860.0 -0.18 102560.0 -11900.0 -0.31 -0.3477 -0.9674 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M22 mock treatment 100200.0 -4820.0 -0.15 108440.0 -6060.0 -0.16 -0.2169 -0.9996 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M23 mock treatment 108080.0 3060.0 0.09 102800.0 -11700.0 -0.3 -0.1479 -0.4644 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base M24 mock treatment 84960.0 -20100.0 -0.62 97880.0 -16600.0 -0.43 -0.7448 -0.9842 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N01 mock treatment 115960.0 10900.0 0.34 123560.0 9060.0 0.24 0.4062 0.9841 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N02 mock treatment 128400.0 23400.0 0.72 150360.0 35900.0 0.93 1.1711 0.9923 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N03 mock treatment 104960.0 -58.9 0.0 102000.0 -12500.0 -0.32 -0.2309 -0.7111 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N04 mock treatment 103600.0 -1420.0 -0.04 104800.0 -9700.0 -0.25 -0.2093 -0.8181 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N05 mock treatment 101240.0 -3780.0 -0.12 116160.0 1660.0 0.04 -0.0523 -0.4189 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N06 mock treatment 108280.0 3260.0 0.1 99520.0 -15000.0 -0.39 -0.2038 -0.5067 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N07 mock treatment 92680.0 -12300.0 -0.38 86520.0 -28000.0 -0.73 -0.7844 -0.955 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N08 mock treatment 93000.0 -12000.0 -0.37 104760.0 -9740.0 -0.25 -0.4423 -0.9823 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N09 mock treatment 89680.0 -15300.0 -0.48 103280.0 -11200.0 -0.29 -0.5422 -0.9725 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N10 mock treatment 84920.0 -20100.0 -0.62 94800.0 -19700.0 -0.51 -0.8023 -0.9953 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N11 mock treatment 88960.0 -16100.0 -0.5 97320.0 -17200.0 -0.45 -0.6675 -0.9985 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N12 mock treatment 105400.0 381.0 0.01 98160.0 -16300.0 -0.42 -0.2918 -0.6872 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N13 mock treatment 105480.0 461.0 0.01 104600.0 -9900.0 -0.26 -0.1718 -0.6668 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N14 mock treatment 91560.0 -13500.0 -0.42 112360.0 -2140.0 -0.06 -0.3342 -0.7943 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N15 mock treatment 85280.0 -19700.0 -0.61 86720.0 -27800.0 -0.72 -0.9428 -0.9966 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N16 mock treatment 96640.0 -8380.0 -0.26 97000.0 -17500.0 -0.45 -0.5051 -0.9647 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N17 mock treatment 93840.0 -11200.0 -0.35 97320.0 -17200.0 -0.45 -0.5605 -0.9921 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N18 mock treatment 88760.0 -16300.0 -0.5 91400.0 -23100.0 -0.6 -0.7806 -0.9962 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N19 mock treatment 92120.0 -12900.0 -0.4 105760.0 -8740.0 -0.23 -0.4432 -0.9641 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N20 mock treatment 98920.0 -6100.0 -0.19 116720.0 2220.0 0.06 -0.0928 -0.4698 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N21 mock treatment 102800.0 -2220.0 -0.07 105840.0 -8660.0 -0.22 -0.2077 -0.8829 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N22 mock treatment 99000.0 -6020.0 -0.19 100120.0 -14400.0 -0.37 -0.3961 -0.9485 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N23 mock treatment 95000.0 -10000.0 -0.31 105760.0 -8740.0 -0.23 -0.3801 -0.9882 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base N24 mock treatment 96440.0 -8580.0 -0.27 106560.0 -7940.0 -0.21 -0.3338 -0.9921 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O01 mock treatment 85200.0 -19800.0 -0.61 118880.0 4380.0 0.11 -0.3537 -0.5664 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O02 mock treatment 118440.0 13400.0 0.42 138240.0 23700.0 0.62 0.7302 0.9816 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O03 mock treatment 101120.0 -3900.0 -0.12 95000.0 -19500.0 -0.51 -0.4437 -0.8518 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O04 mock treatment 100040.0 -4980.0 -0.15 114240.0 -259.0 -0.01 -0.1138 -0.7373 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O05 mock treatment 94840.0 -10200.0 -0.32 94280.0 -20200.0 -0.53 -0.5945 -0.9702 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O06 mock treatment 98160.0 -6860.0 -0.21 103440.0 -11100.0 -0.29 -0.3535 -0.989 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O07 mock treatment 88080.0 -16900.0 -0.52 85040.0 -29500.0 -0.77 -0.9124 -0.9831 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O08 mock treatment 99680.0 -5340.0 -0.17 83440.0 -31100.0 -0.81 -0.6876 -0.8347 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O09 mock treatment 89000.0 -16000.0 -0.5 86840.0 -27700.0 -0.72 -0.8591 -0.9837 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O10 mock treatment 88240.0 -16800.0 -0.52 92000.0 -22500.0 -0.58 -0.781 -0.9983 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O11 mock treatment 96560.0 -8460.0 -0.26 104160.0 -10300.0 -0.27 -0.3753 -0.9999 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O12 mock treatment 83840.0 -21200.0 -0.66 93080.0 -21400.0 -0.56 -0.8575 -0.9966 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O13 mock treatment 102400.0 -2620.0 -0.08 96560.0 -17900.0 -0.47 -0.387 -0.8179 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O14 mock treatment 94000.0 -11000.0 -0.34 95240.0 -19300.0 -0.5 -0.5953 -0.9826 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O15 mock treatment 100120.0 -4900.0 -0.15 99440.0 -15100.0 -0.39 -0.384 -0.915 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O16 mock treatment 93320.0 -11700.0 -0.36 87800.0 -26700.0 -0.69 -0.7468 -0.9542 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O17 mock treatment 93440.0 -11600.0 -0.36 97880.0 -16600.0 -0.43 -0.559 -0.9958 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O18 mock treatment 85480.0 -19500.0 -0.61 77960.0 -36500.0 -0.95 -1.0994 -0.9764 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O19 mock treatment 94640.0 -10400.0 -0.32 103240.0 -11300.0 -0.29 -0.4343 -0.9989 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O20 mock treatment 91840.0 -13200.0 -0.41 103800.0 -10700.0 -0.28 -0.4853 -0.9824 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O21 mock treatment 91960.0 -13100.0 -0.4 98280.0 -16200.0 -0.42 -0.5841 -0.9998 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O22 mock treatment 88560.0 -16500.0 -0.51 98200.0 -16300.0 -0.42 -0.6601 -0.9957 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O23 mock treatment 95600.0 -9420.0 -0.29 108360.0 -6140.0 -0.16 -0.3192 -0.9596 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base O24 mock treatment 111200.0 6180.0 0.19 99600.0 -14900.0 -0.39 -0.1383 -0.3202 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P01 mock treatment 61760.0 -43300.0 -1.34 84360.0 -30100.0 -0.78 -1.5015 -0.9672 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P02 mock treatment 101680.0 -3340.0 -0.1 118960.0 4460.0 0.12 0.0088 0.0567 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P03 mock treatment 111720.0 6700.0 0.21 102400.0 -12100.0 -0.31 -0.0755 -0.2003 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P04 mock treatment 111240.0 6220.0 0.19 106720.0 -7780.0 -0.2 -0.0066 -0.0237 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P05 mock treatment 95400.0 -9620.0 -0.3 96040.0 -18500.0 -0.48 -0.5499 -0.9738 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P06 mock treatment 101160.0 -3860.0 -0.12 91400.0 -23100.0 -0.6 -0.5089 -0.8316 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P07 mock treatment 98560.0 -6460.0 -0.2 92480.0 -22000.0 -0.57 -0.5461 -0.9009 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P08 mock treatment 88600.0 -16400.0 -0.51 85920.0 -28600.0 -0.74 -0.8848 -0.983 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P09 mock treatment 96440.0 -8580.0 -0.27 85520.0 -29000.0 -0.75 -0.7204 -0.9022 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P10 mock treatment 95640.0 -9380.0 -0.29 84240.0 -30300.0 -0.79 -0.7614 -0.9084 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P11 mock treatment 96800.0 -8220.0 -0.25 89400.0 -25100.0 -0.65 -0.6412 -0.9159 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P12 mock treatment 101160.0 -3860.0 -0.12 108320.0 -6180.0 -0.16 -0.1981 -0.9895 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P13 mock treatment 94520.0 -10500.0 -0.33 94520.0 -20000.0 -0.52 -0.5971 -0.9747 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P14 mock treatment 100200.0 -4820.0 -0.15 95520.0 -19000.0 -0.49 -0.4543 -0.8817 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P15 mock treatment 97160.0 -7860.0 -0.24 97520.0 -17000.0 -0.44 -0.4841 -0.9608 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P16 mock treatment 87560.0 -17500.0 -0.54 77960.0 -36500.0 -0.95 -1.0538 -0.9644 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P17 mock treatment 100200.0 -4820.0 -0.15 86200.0 -28300.0 -0.74 -0.6255 -0.8337 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P18 mock treatment 96560.0 -8460.0 -0.26 77360.0 -37100.0 -0.96 -0.8677 -0.8677 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P19 mock treatment 106000.0 981.0 0.03 81120.0 -33400.0 -0.87 -0.5918 -0.6819 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P20 mock treatment 107480.0 2460.0 0.08 97160.0 -17300.0 -0.45 -0.2646 -0.5792 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P21 mock treatment 104760.0 -259.0 -0.01 94840.0 -19700.0 -0.51 -0.3669 -0.7181 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P22 mock treatment 102520.0 -2500.0 -0.08 93320.0 -21200.0 -0.55 -0.4439 -0.7987 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P23 mock treatment 83600.0 -21400.0 -0.66 103920.0 -10600.0 -0.27 -0.6636 -0.9239 1108.0003 CellTiterGlo(1108.0003) e-CadherinSyntheticLethalAssay 1108.0003.Base P24 mock treatment 56120.0 -48900.0 -1.52 87760.0 -26700.0 -0.69 -1.5626 -0.9375