ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A01 compound treatment 2680.0 2260.0 14.99 1320.0 832.0 5.42 14.4328 0.9053 3652363 HDAC1-H_000001 COc1cc2nc(Cl)nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A02 compound treatment 280.0 -138.0 -0.91 360.0 -128.0 -0.83 -1.2338 -0.9988 3652364 HDAC1-H_000002 ONC(=O)CCc1cn(nn1)c2cccc(c2)C(=O)N3CCN(CC3)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A03 compound treatment 2120.0 1700.0 11.28 2280.0 1790.0 11.66 16.225 0.9999 3652365 HDAC1-H_000003 COc1cc2nc(Cl)nc(NC3CCCCC3)c2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A04 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652366 HDAC1-H_000004 COc1ccc(NC(=O)Cn2cc(CCC(=O)NO)nn2)cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A05 compound treatment 360.0 -58.0 -0.38 320.0 -168.0 -1.09 -1.0429 -0.9019 3652367 HDAC1-H_000005 COc1cc2nc(Cl)nc(Nc3ccc(F)c(Cl)c3)c2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A06 compound treatment 280.0 -138.0 -0.91 320.0 -168.0 -1.09 -1.4179 -0.9962 3652368 HDAC1-H_000006 ONC(=O)CCc1cn(nn1)c2ccc3[nH]ccc3c2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A07 compound treatment 120.0 -298.0 -1.98 280.0 -208.0 -1.35 -2.3519 -0.9828 3650892 HDAC1-H_000007 COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N5CCCN(C)CC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A08 compound treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 3652369 HDAC1-H_000008 CCOc1cc(OCC)cc(c1)C(=O)N[C@@H](Cc2ccc(cc2)n3cc(CCC(=O)NO)nn3)C(=O)OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A09 compound treatment 240.0 -178.0 -1.18 920.0 432.0 2.81 1.1553 0.3787 3652371 HDAC1-H_000009 COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N5CCCCCC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A10 compound treatment 80.0 -338.0 -2.24 160.0 -328.0 -2.13 -3.0915 -0.9997 3652372 HDAC1-H_000010 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)c2cccc(/C=C/C(=O)NO)c2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A11 compound treatment 40.0 -378.0 -2.51 200.0 -288.0 -1.87 -3.0949 -0.9897 3652374 HDAC1-H_000011 COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N5CCCN(Cc6ccccc6)CC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A12 compound treatment 240.0 -178.0 -1.18 400.0 -87.6 -0.57 -1.2373 -0.9443 3652375 HDAC1-H_000012 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCn2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A13 mock treatment 360.0 -58.0 -0.38 480.0 -7.62 -0.05 -0.3067 -0.7918 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A14 mock treatment 280.0 -138.0 -0.91 400.0 -87.6 -0.57 -1.0498 -0.9741 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A15 compound treatment 1480.0 1060.0 7.04 1960.0 1470.0 9.58 11.7527 0.9885 3652377 HDAC1-H_000013 COc1cc2nc(nc(NC3CCCCC3)c2cc1OC)N4CCCN(C)CC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A16 compound treatment 400.0 -18.0 -0.12 560.0 72.4 0.47 0.2489 0.5123 3652378 HDAC1-H_000014 COc1ccc(cc1)n2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A17 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652380 HDAC1-H_000015 COc1cc2nc(nc(NC3CCCCC3)c2cc1OC)N4CCCCCC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A18 compound treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 3652381 HDAC1-H_000016 COC(=O)[C@@H](NC(=O)Cn1cc(CCC(=O)NO)nn1)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A19 compound treatment 80.0 -338.0 -2.24 200.0 -288.0 -1.87 -2.9075 -0.996 3652383 HDAC1-H_000017 COc1cc2nc(nc(NC3CCCCC3)c2cc1OC)N4CCCN(Cc5ccccc5)CC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A20 compound treatment 320.0 -98.0 -0.65 360.0 -128.0 -0.83 -1.0463 -0.9926 3652384 HDAC1-H_000018 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCn2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A21 compound treatment 80.0 -338.0 -2.24 120.0 -368.0 -2.39 -3.2755 -0.9995 3652386 HDAC1-H_000019 COc1cc2nc(nc(Nc3ccc(F)c(Cl)c3)c2cc1OC)N4CCCN(C)CC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A22 compound treatment 200.0 -218.0 -1.44 240.0 -248.0 -1.61 -2.1609 -0.9985 3652387 HDAC1-H_000020 COc1ccc(cc1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A23 compound treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 3652388 HDAC1-H_000021 COc1cc2nc(nc(Nc3ccc(F)c(Cl)c3)c2cc1OC)N4CCCCCC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 A24 compound treatment 200.0 -218.0 -1.44 160.0 -328.0 -2.13 -2.529 -0.982 3652372 HDAC1-H_000022 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)c2cccc(/C=C/C(=O)NO)c2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B01 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 1003435 HDAC1-H_000023 OC(=O)c1ccc(O)c(c1)C(=O)O 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B02 compound treatment 360.0 -58.0 -0.38 360.0 -128.0 -0.83 -0.8588 -0.9386 3652389 HDAC1-H_000024 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@@H]2O[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)C[C@@H](O2)c6ccccc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B03 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652390 HDAC1-H_000025 O=C(NCCCNC(=O)c1ccccn1)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B04 compound treatment 240.0 -178.0 -1.18 400.0 -87.6 -0.57 -1.2373 -0.9443 3652391 HDAC1-H_000026 NCCCn1cc(CNc2ccc(cc2)C(=O)NCCCCCCC(=O)NO)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B05 compound treatment 320.0 -98.0 -0.65 520.0 32.4 0.21 -0.3101 -0.4543 3652392 HDAC1-H_000027 COC(=O)c1ccc(nc1)C(=O)NCCCNC(=O)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B06 compound treatment 280.0 -138.0 -0.91 360.0 -128.0 -0.83 -1.2338 -0.9988 3635011 HDAC1-H_000028 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B07 compound treatment 280.0 -138.0 -0.91 400.0 -87.6 -0.57 -1.0498 -0.9741 3652393 HDAC1-H_000029 O=C(NCCCCNC(=O)c1ccccn1)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B08 compound treatment 240.0 -178.0 -1.18 360.0 -128.0 -0.83 -1.4213 -0.9852 3634742 HDAC1-H_000030 CN(C[C@H]1C[C@H](OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccc(CO)cc3)Cc4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B09 compound treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 3652394 HDAC1-H_000031 COC(=O)c1ccc(nc1)C(=O)NCCCCNC(=O)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B10 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3634942 HDAC1-H_000032 ONC(=O)CCCCCCC(=O)Nc1cccc(c1)C(=O)NCCOCCOCCNC(=O)c2cccc(NC(=O)CCCCCCC(=O)NO)c2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B11 compound treatment 280.0 -138.0 -0.91 400.0 -87.6 -0.57 -1.0498 -0.9741 3652395 HDAC1-H_000033 O=C(NCCCCCNC(=O)c1ccccn1)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B12 compound treatment 200.0 -218.0 -1.44 320.0 -168.0 -1.09 -1.7928 -0.9904 3634875 HDAC1-H_000034 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)NCCOCCOCCNC(=O)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B13 mock treatment 240.0 -178.0 -1.18 480.0 -7.62 -0.05 -0.8692 -0.7362 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B14 mock treatment 240.0 -178.0 -1.18 360.0 -128.0 -0.83 -1.4213 -0.9852 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B15 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652396 HDAC1-H_000035 O=C(NCCCCCCNC(=O)c1ccccn1)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B16 compound treatment 320.0 -98.0 -0.65 360.0 -128.0 -0.83 -1.0463 -0.9926 3652397 HDAC1-H_000036 ONC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3ccc(Cn4cc(CNc5ccc(cc5)C(=O)NCCCCCCC(=O)O)nn4)cc3)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B17 compound treatment 320.0 -98.0 -0.65 480.0 -7.62 -0.05 -0.4942 -0.7589 3652398 HDAC1-H_000037 COC(=O)c1ccc(nc1)C(=O)NCCCCCCNC(=O)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B18 compound treatment 200.0 -218.0 -1.44 400.0 -87.6 -0.57 -1.4248 -0.9173 3635064 HDAC1-H_000038 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4o3)CC(O2)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B19 compound treatment 200.0 -218.0 -1.44 440.0 -47.6 -0.31 -1.2407 -0.8397 3652399 HDAC1-H_000039 CC(C)(C)OC(=O)NCCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B20 compound treatment 240.0 -178.0 -1.18 360.0 -128.0 -0.83 -1.4213 -0.9852 3634604 HDAC1-H_000040 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN3CCCCCCC3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B21 compound treatment 280.0 -138.0 -0.91 360.0 -128.0 -0.83 -1.2338 -0.9988 3652400 HDAC1-H_000041 CC(C)(C)OC(=O)NCCCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B22 compound treatment 320.0 -98.0 -0.65 280.0 -208.0 -1.35 -1.4144 -0.9436 3634671 HDAC1-H_000042 CN(CC=C)CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B23 compound treatment 360.0 -58.0 -0.38 240.0 -248.0 -1.61 -1.411 -0.8518 3652401 HDAC1-H_000043 CC(C)(C)OC(=O)NCCCCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 B24 compound treatment 520.0 102.0 0.68 280.0 -208.0 -1.35 -0.477 -0.3157 3652402 HDAC1-H_000044 ONC(=O)/C=C/c1ccc(CNCCc2c[nH]c3ccccc23)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C01 compound treatment 320.0 -98.0 -0.65 520.0 32.4 0.21 -0.3101 -0.4543 3652404 HDAC1-H_000045 COc1cc2nc(nc(Nc3ccc(F)c(Cl)c3)c2cc1OC)N4CCCN(Cc5ccccc5)CC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C02 compound treatment 320.0 -98.0 -0.65 480.0 -7.62 -0.05 -0.4942 -0.7589 3652375 HDAC1-H_000046 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCn2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C03 compound treatment 200.0 -218.0 -1.44 360.0 -128.0 -0.83 -1.6088 -0.9654 1429650 HDAC1-H_000047 COc1cc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C04 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652405 HDAC1-H_000048 COc1ccc(OC)c(NC(=O)Cn2cc(nn2)c3cccc(/C=C/C(=O)NO)c3)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C05 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3652407 HDAC1-H_000049 COc1cc2nc(Cl)nc(OC3CCN(Cc4ccccc4)CC3)c2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C06 compound treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 3652408 HDAC1-H_000050 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)c4cccc(/C=C/C(=O)NO)c4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C07 compound treatment 1200.0 782.0 5.18 600.0 112.0 0.73 4.1828 0.7989 3652410 HDAC1-H_000051 COc1cc2nc(nc(OC3CCN(Cc4ccccc4)CC3)c2cc1OC)N5CCCN(C)CC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C08 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652411 HDAC1-H_000052 ONC(=O)/C=C/c1cccc(c1)c2cn(CC(=O)N3CCOCC3)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C09 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652413 HDAC1-H_000053 Oc1nc(O)c2cc(Br)ccc2n1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C10 compound treatment 360.0 -58.0 -0.38 280.0 -208.0 -1.35 -1.2269 -0.8735 3652414 HDAC1-H_000054 CN1CCN(CC1)C(=O)Cn2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C11 mock treatment 320.0 -98.0 -0.65 520.0 32.4 0.21 -0.3101 -0.4543 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C12 mock treatment 320.0 -98.0 -0.65 280.0 -208.0 -1.35 -1.4144 -0.9436 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C13 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652416 HDAC1-H_000055 Clc1nc(Cl)c2cc(Br)ccc2n1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C14 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652417 HDAC1-H_000056 ONC(=O)/C=C/c1cccc(c1)c2cn(CC(=O)Nc3nccs3)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C15 mock treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C16 mock treatment 320.0 -98.0 -0.65 520.0 32.4 0.21 -0.3101 -0.4543 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C17 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652419 HDAC1-H_000057 COc1ccc2nc(O)nc(O)c2c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C18 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652420 HDAC1-H_000058 ONC(=O)/C=C/c1cccc(c1)c2cn(CC(=O)Nc3ccon3)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C19 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652422 HDAC1-H_000059 Clc1nc(NC2CCCCC2)c3cc(Br)ccc3n1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C20 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652423 HDAC1-H_000060 ONC(=O)/C=C/c1cccc(c1)c2cn(CCCNC(=O)Nc3ccccc3)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C21 compound treatment 480.0 62.0 0.41 360.0 -128.0 -0.83 -0.2964 -0.3198 3652425 HDAC1-H_000061 COc1ccc2nc(Cl)nc(Cl)c2c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C22 compound treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 3652426 HDAC1-H_000062 ONC(=O)/C=C/c1cccc(c1)c2cn(CCNC(=O)Nc3ccccc3)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C23 compound treatment 320.0 -98.0 -0.65 440.0 -47.6 -0.31 -0.6782 -0.9427 3652428 HDAC1-H_000063 Clc1nc(NC2CCN(Cc3ccccc3)CC2)c4cc(Br)ccc4n1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 C24 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652429 HDAC1-H_000064 ONC(=O)/C=C/c1cccc(c1)c2cn(C[C@H](Cc3ccccc3)NC(=O)c4ccccc4)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D01 compound treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 3652431 HDAC1-H_000065 CC(C)(C)OC(=O)NCCCCCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D02 compound treatment 560.0 142.0 0.94 480.0 -7.62 -0.05 0.6308 0.669 3652432 HDAC1-H_000066 ONC(=O)/C=C/c1ccc(CN(CCc2c[nH]c3ccccc23)C(=O)CCCCC(=O)N(CCc4c[nH]c5ccccc45)Cc6ccc(\C=C\C(=O)NO)cc6)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D03 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652434 HDAC1-H_000067 COC(=O)[C@H](CCCCNC(=O)c1ccccn1)NC(=O)OC(C)(C)C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D04 compound treatment 280.0 -138.0 -0.91 240.0 -248.0 -1.61 -1.7859 -0.964 3652436 HDAC1-H_000068 OCCN(CCc1c[nH]c2ccccc12)Cc3ccc(/C=C/C(=O)O)cc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D05 compound treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 3652438 HDAC1-H_000069 COC(=O)c1ccc(nc1)C(=O)NCCCNC(=O)OC(C)(C)C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D06 compound treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 3652439 HDAC1-H_000070 OC(=O)/C=C/c1ccc(CNCCc2c[nH]c3ccccc23)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D07 compound treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 3652441 HDAC1-H_000071 COC(=O)c1ccc(nc1)C(=O)NCCCCNC(=O)OC(C)(C)C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D08 compound treatment 320.0 -98.0 -0.65 360.0 -128.0 -0.83 -1.0463 -0.9926 3622998 HDAC1-H_000072 OCCN(CCc1c[nH]c2ccccc12)Cc3ccc(/C=C/C(=O)NO)cc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D09 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652442 HDAC1-H_000073 COC(=O)c1ccc(nc1)C(=O)NCCCCCNC(=O)OC(C)(C)C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D10 mock treatment 440.0 22.0 0.15 320.0 -168.0 -1.09 -0.6679 -0.6069 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D11 mock treatment 320.0 -98.0 -0.65 480.0 -7.62 -0.05 -0.4942 -0.7589 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D12 mock treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D13 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652443 HDAC1-H_000074 COC(=O)[C@H](CCCCNC(=O)c1ccc(cn1)C(=O)OC)NC(=O)OC(C)(C)C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D14 mock treatment 280.0 -138.0 -0.91 520.0 32.4 0.21 -0.4976 -0.5303 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D15 mock treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D16 mock treatment 240.0 -178.0 -1.18 400.0 -87.6 -0.57 -1.2373 -0.9443 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D17 compound treatment 400.0 -18.0 -0.12 600.0 112.0 0.73 0.4329 0.5843 3652445 HDAC1-H_000075 CCOC(=O)CCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D18 mock treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D19 compound treatment 320.0 -98.0 -0.65 280.0 -208.0 -1.35 -1.4144 -0.9436 3652446 HDAC1-H_000076 CCOC(=O)CCCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D20 mock treatment 240.0 -178.0 -1.18 480.0 -7.62 -0.05 -0.8692 -0.7362 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D21 compound treatment 280.0 -138.0 -0.91 480.0 -7.62 -0.05 -0.6817 -0.7443 3652447 HDAC1-H_000077 COC(=O)CCCCCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D22 mock treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D23 compound treatment 600.0 182.0 1.21 440.0 -47.6 -0.31 0.6342 0.509 3652448 HDAC1-H_000078 CN(CCCNC(=O)c1ccccc1)CC#C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 D24 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E01 mock treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E02 mock treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E03 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 3652449 HDAC1-H_000079 COc1ccc2nc(Cl)nc(NC3CCN(Cc4ccccc4)CC3)c2c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E04 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652450 HDAC1-H_000080 ONC(=O)/C=C/c1cccc(c1)c2cn(CC(=O)N3CCC4(CC3)N(CNC4=O)c5ccccc5)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E05 compound treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 3652452 HDAC1-H_000081 COc1ccc2nc(Cl)nc(NC3CCCCC3)c2c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E06 compound treatment 280.0 -138.0 -0.91 440.0 -47.6 -0.31 -0.8657 -0.8966 3652453 HDAC1-H_000082 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E07 compound treatment 160.0 -258.0 -1.71 240.0 -248.0 -1.61 -2.3484 -0.9996 3652455 HDAC1-H_000083 COc1cc2nc(Cl)nc(Cl)c2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E08 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652456 HDAC1-H_000084 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4cccc(/C=C/C(=O)NO)c4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E09 mock treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E10 mock treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E11 compound treatment 200.0 -218.0 -1.44 240.0 -248.0 -1.61 -2.1609 -0.9985 3652458 HDAC1-H_000085 CN1CCCN(CC1)c2nc(NC3CCN(Cc4ccccc4)CC3)c5cc(Br)ccc5n2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E12 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652459 HDAC1-H_000086 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4cccc(/C=C/C(=O)NO)c4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E13 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652461 HDAC1-H_000087 Brc1ccc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2c1)N5CCCN(Cc6ccccc6)CC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E14 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3652462 HDAC1-H_000088 ONC(=O)/C=C/c1cccc(c1)c2cn(C[C@H](Cc3ccccc3)NC(=O)Nc4ccccc4)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E15 compound treatment 320.0 -98.0 -0.65 440.0 -47.6 -0.31 -0.6782 -0.9427 3652464 HDAC1-H_000089 Brc1ccc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2c1)N5CCCCCC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E16 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652465 HDAC1-H_000090 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4cccc(/C=C/C(=O)NO)c4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E17 mock treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E18 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E19 compound treatment 160.0 -258.0 -1.71 360.0 -128.0 -0.83 -1.7963 -0.945 3652467 HDAC1-H_000091 COc1ccc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2c1)N5CCCN(C)CC5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E20 compound treatment 320.0 -98.0 -0.65 360.0 -128.0 -0.83 -1.0463 -0.9926 3652468 HDAC1-H_000092 CC(C)(C)OC(=O)N/C(=N\C(=O)OC(C)(C)C)/NCCn1cc(nn1)c2cccc(/C=C/C(=O)NO)c2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E21 compound treatment 1160.0 742.0 4.92 1320.0 832.0 5.42 7.3081 0.9988 3652470 HDAC1-H_000093 CN1CCCN(CC1)c2nc(NC3CCCCC3)c4cc(Br)ccc4n2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E22 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652471 HDAC1-H_000094 CC(C)(C)OC(=O)N/C(=N\C(=O)OC(C)(C)C)/NCCCn1cc(nn1)c2cccc(/C=C/C(=O)NO)c2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E23 compound treatment 360.0 -58.0 -0.38 360.0 -128.0 -0.83 -0.8588 -0.9386 3652473 HDAC1-H_000095 Brc1ccc2nc(nc(NC3CCCCC3)c2c1)N4CCCCCC4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 E24 compound treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 3652474 HDAC1-H_000096 CC(C)(C)ONC(=O)c1cccc(c1)n2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F01 mock treatment 520.0 102.0 0.68 480.0 -7.62 -0.05 0.4433 0.6535 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F02 mock treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F03 compound treatment 440.0 22.0 0.15 320.0 -168.0 -1.09 -0.6679 -0.6069 3652476 HDAC1-H_000097 CN(CCCCNC(=O)c1ccccc1)CC#C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F04 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F05 compound treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 3652477 HDAC1-H_000098 CN(CCCCCCNC(=O)c1ccccc1)CC#C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F06 mock treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F07 compound treatment 360.0 -58.0 -0.38 480.0 -7.62 -0.05 -0.3067 -0.7918 3652478 HDAC1-H_000099 COC(=O)C(=O)NCCCCCCNC(=O)c1ccccc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F08 mock treatment 320.0 -98.0 -0.65 640.0 152.0 0.99 0.242 0.2042 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F09 mock treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F10 mock treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F11 compound treatment 480.0 62.0 0.41 520.0 32.4 0.21 0.4398 0.9517 3652479 HDAC1-H_000100 O=C(NCCCCNC(=O)c1ccccn1)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F12 mock treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F13 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652480 HDAC1-H_000101 O=C(NCCCCCNC(=O)c1ccccn1)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F14 mock treatment 320.0 -98.0 -0.65 560.0 72.4 0.47 -0.1261 -0.1572 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F15 compound treatment 480.0 62.0 0.41 600.0 112.0 0.73 0.8079 0.963 3652481 HDAC1-H_000102 O=C(NCCCCCCNC(=O)c1ccccn1)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F16 mock treatment 560.0 142.0 0.94 440.0 -47.6 -0.31 0.4467 0.4506 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F17 mock treatment 360.0 -58.0 -0.38 360.0 -128.0 -0.83 -0.8588 -0.9386 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F18 mock treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F19 compound treatment 360.0 -58.0 -0.38 480.0 -7.62 -0.05 -0.3067 -0.7918 3652482 HDAC1-H_000103 COC(=O)c1ccc(nc1)C(=O)NCCCCCNC(=O)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F20 mock treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F21 compound treatment 360.0 -58.0 -0.38 320.0 -168.0 -1.09 -1.0429 -0.9019 3616541 HDAC1-H_000104 N[C@H]1C[C@@H]1c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F22 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F23 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1088402 HDAC1-H_000105 COC(=O)c1ccc(nc1)C(=O)O 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 F24 mock treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G01 compound treatment 560.0 142.0 0.94 560.0 72.4 0.47 0.9989 0.9487 3652483 HDAC1-H_000106 COc1cccc(c1)n2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G02 compound treatment 560.0 142.0 0.94 560.0 72.4 0.47 0.9989 0.9487 3652378 HDAC1-H_000107 COc1ccc(cc1)n2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G03 mock treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G04 mock treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G05 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652484 HDAC1-H_000108 COc1ccc(cc1)n2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G06 compound treatment 440.0 22.0 0.15 680.0 192.0 1.25 0.9885 0.7843 3652485 HDAC1-H_000109 COc1cccc(c1)n2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G07 compound treatment 480.0 62.0 0.41 520.0 32.4 0.21 0.4398 0.9517 3652487 HDAC1-H_000110 ONC(=O)c1cn(nn1)c2cccc(c2)C(=O)N3CCC4(CC3)N(CNC4=O)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G08 compound treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 3652488 HDAC1-H_000111 CC(C)(C)ONC(=O)Cn1cc(nn1)c2cccc(/C=C/C(=O)NO)c2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G09 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652490 HDAC1-H_000112 COC(=O)c1ccc(Cn2cc(nn2)C(=O)NO)o1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G10 compound treatment 400.0 -18.0 -0.12 680.0 192.0 1.25 0.801 0.637 3652491 HDAC1-H_000113 ONC(=O)/C=C/c1cccc(c1)c2cn(nn2)c3ccc(NC(=O)c4ccccc4)cc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G11 compound treatment 520.0 102.0 0.68 480.0 -7.62 -0.05 0.4433 0.6535 3652493 HDAC1-H_000114 COC(=O)[C@@H](N)Cc1ccc(cc1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G12 compound treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 3652495 HDAC1-H_000115 Nc1ccc(cc1)n2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G13 compound treatment 360.0 -58.0 -0.38 480.0 -7.62 -0.05 -0.3067 -0.7918 3652497 HDAC1-H_000116 Nc1ccc(cc1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G14 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 3652498 HDAC1-H_000117 Nc1cccc(c1)n2cc(nn2)c3cccc(/C=C/C(=O)NO)c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G15 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652500 HDAC1-H_000118 Nc1cccc(c1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G16 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652501 HDAC1-H_000119 ONC(=O)/C=C/c1cccc(c1)c2cn(nn2)c3cccc(c3)C(=O)N4CCC5(CC4)N(CNC5=O)c6ccccc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G17 compound treatment 360.0 -58.0 -0.38 320.0 -168.0 -1.09 -1.0429 -0.9019 3652503 HDAC1-H_000120 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)NO)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G18 compound treatment 360.0 -58.0 -0.38 480.0 -7.62 -0.05 -0.3067 -0.7918 3652505 HDAC1-H_000121 ONC(=O)/C=C/c1cccc(c1)c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G19 mock treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G20 mock treatment 440.0 22.0 0.15 360.0 -128.0 -0.83 -0.4838 -0.5738 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G21 compound treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 3652507 HDAC1-H_000122 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCn2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G22 compound treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 3652509 HDAC1-H_000123 COc1ccc(cc1)C(=O)Nc2cccc(c2)n3cc(nn3)c4cccc(/C=C/C(=O)NO)c4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G23 compound treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 3652511 HDAC1-H_000124 COc1ccc(OC)c(NC(=O)Cn2cc(nn2)C(=O)NO)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 G24 compound treatment 400.0 -18.0 -0.12 360.0 -128.0 -0.83 -0.6713 -0.8003 3652512 HDAC1-H_000125 ONC(=O)/C=C/c1cccc(c1)c2cn(nn2)c3cccc(c3)C(=O)N4CCN(CC4)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H01 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 1002773 HDAC1-H_000126 OC(=O)c1ccc(nc1)C(=O)O 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H02 mock treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H03 mock treatment 560.0 142.0 0.94 520.0 32.4 0.21 0.8148 0.8445 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H04 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H05 compound treatment 440.0 22.0 0.15 600.0 112.0 0.73 0.6204 0.832 3614749 HDAC1-H_000127 COC(=O)CNC(=O)C(=O)OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H06 mock treatment 440.0 22.0 0.15 600.0 112.0 0.73 0.6204 0.832 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H07 compound treatment 560.0 142.0 0.94 520.0 32.4 0.21 0.8148 0.8445 3652514 HDAC1-H_000128 OC(=O)CNC(=O)C(=O)O 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H08 mock treatment 360.0 -58.0 -0.38 600.0 112.0 0.73 0.2454 0.2971 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H09 compound treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 3652515 HDAC1-H_000129 CCOC(=O)/C=C/c1ccc(O)c(O)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H10 mock treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H11 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1978 HDAC1-H_000130 OC(=O)/C=C/c1ccc(O)c(O)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H12 mock treatment 480.0 62.0 0.41 720.0 232.0 1.51 1.36 0.8679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H13 compound treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 831713 HDAC1-H_000131 OC(=O)c1ccc(O)c(O)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H14 mock treatment 760.0 342.0 2.27 760.0 272.0 1.77 2.8565 0.9926 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H15 compound treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 1070606 HDAC1-H_000132 COC(=O)c1ccc(O)c(O)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H16 mock treatment 400.0 -18.0 -0.12 600.0 112.0 0.73 0.4329 0.5843 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H17 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652517 HDAC1-H_000133 COC(=O)c1ccc(nc1)C(=O)NCCCCCNC(=O)OCc2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H18 mock treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H19 mock treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H20 mock treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H21 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 3652518 HDAC1-H_000134 COC(=O)c1ccc(nc1)C(=O)NCCCCCCNC(=O)OC(C)(C)C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H22 mock treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H23 compound treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 3652519 HDAC1-H_000135 CCOC(=O)CCNC(=O)c1ccccn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 H24 mock treatment 280.0 -138.0 -0.91 600.0 112.0 0.73 -0.1295 -0.1106 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I01 compound treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 3652520 HDAC1-H_000136 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I02 compound treatment 520.0 102.0 0.68 360.0 -128.0 -0.83 -0.1089 -0.1016 3652522 HDAC1-H_000137 COc1ccc(NC(=O)Cn2cc(nn2)c3cccc(/C=C/C(=O)NO)c3)cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I03 compound treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 3652524 HDAC1-H_000138 ONC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I04 compound treatment 640.0 222.0 1.47 640.0 152.0 0.99 1.7419 0.9815 3652525 HDAC1-H_000139 ONC(=O)/C=C/c1cccc(c1)c2cn(nn2)c3ccc4[nH]ccc4c3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I05 mock treatment 360.0 -58.0 -0.38 640.0 152.0 0.99 0.4295 0.4039 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I06 mock treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I07 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3652527 HDAC1-H_000140 ONC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I08 compound treatment 440.0 22.0 0.15 640.0 152.0 0.99 0.8045 0.8027 3652528 HDAC1-H_000141 CCOc1cc(OCC)cc(c1)C(=O)N[C@@H](Cc2ccc(cc2)n3cc(nn3)c4cccc(/C=C/C(=O)NO)c4)C(=O)OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I09 compound treatment 400.0 -18.0 -0.12 640.0 152.0 0.99 0.617 0.6178 3652530 HDAC1-H_000142 ONC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I10 compound treatment 2920.0 2500.0 16.59 3600.0 3110.0 20.25 26.0483 0.9951 3622981 HDAC1-H_000143 Nc1ccccc1NC(=O)c2ccc(CNc3nccc(n3)c4cccnc4)cc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I11 compound treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 3652532 HDAC1-H_000144 ONC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I12 compound treatment 2520.0 2100.0 13.93 3520.0 3030.0 19.73 23.8052 0.9855 3652533 HDAC1-H_000145 COc1ccc(NCc2ccc(cc2)C(=O)Nc3ccccc3N)cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I13 compound treatment 480.0 62.0 0.41 640.0 152.0 0.99 0.992 0.9241 3652534 HDAC1-H_000146 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I14 compound treatment 14800.0 14400.0 95.34 12560.0 12100.0 78.55 122.9594 0.9954 3652536 HDAC1-H_000147 Cc1ccc(NCc2ccc(cc2)C(=O)Nc3ccccc3N)cc1C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I15 compound treatment 680.0 262.0 1.74 720.0 232.0 1.51 2.2975 0.9976 3652537 HDAC1-H_000148 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I16 compound treatment 440.0 22.0 0.15 600.0 112.0 0.73 0.6204 0.832 3652539 HDAC1-H_000149 O=C(Nc1ccccc1)c2ccc(CNc3nccc(n3)c4cccnc4)cc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I17 compound treatment 440.0 22.0 0.15 400.0 -87.6 -0.57 -0.2998 -0.5094 3652540 HDAC1-H_000150 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I18 compound treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 3652542 HDAC1-H_000151 COc1ccc(NCc2ccc(cc2)C(=O)Nc3ccccc3)cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I19 compound treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 3652543 HDAC1-H_000152 ONC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I20 compound treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 3652545 HDAC1-H_000153 [O-][N+](=O)c1ccccc1NC(=O)c2ccc(CNc3nccc(n3)c4cccnc4)cc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I21 mock treatment 560.0 142.0 0.94 400.0 -87.6 -0.57 0.2627 0.2386 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I22 mock treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I23 compound treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 3652546 HDAC1-H_000154 ONC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 I24 compound treatment 680.0 262.0 1.74 800.0 312.0 2.03 2.6656 0.9969 3652547 HDAC1-H_000155 Cc1ccc(NCc2ccc(cc2)C(=O)Nc3ccccc3)cc1C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J01 compound treatment 480.0 62.0 0.41 720.0 232.0 1.51 1.36 0.8679 3652548 HDAC1-H_000156 CN(CCCCCNC(=O)c1ccccc1)CC#C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J02 mock treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J03 compound treatment 480.0 62.0 0.41 520.0 32.4 0.21 0.4398 0.9517 3652549 HDAC1-H_000157 COC(=O)C(=O)NCCCCCNC(=O)c1ccccc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J04 mock treatment 600.0 182.0 1.21 600.0 112.0 0.73 1.3704 0.9712 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J05 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J06 mock treatment 480.0 62.0 0.41 400.0 -87.6 -0.57 -0.1123 -0.1598 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J07 compound treatment 400.0 -18.0 -0.12 600.0 112.0 0.73 0.4329 0.5843 3652550 HDAC1-H_000158 COC(=O)c1ccc(nc1)C(=O)NCCCCNC(=O)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J08 mock treatment 480.0 62.0 0.41 760.0 272.0 1.77 1.5441 0.8486 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J09 compound treatment 600.0 182.0 1.21 440.0 -47.6 -0.31 0.6342 0.509 1025079 HDAC1-H_000159 COC(=O)c1ccc(nc1)C(=O)OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J10 mock treatment 600.0 182.0 1.21 600.0 112.0 0.73 1.3704 0.9712 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J11 compound treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 3635106 HDAC1-H_000160 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(COc3ccccc3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J12 mock treatment 480.0 62.0 0.41 600.0 112.0 0.73 0.8079 0.963 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J13 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3635115 HDAC1-H_000161 COCC1CC(OC(O1)c2ccc(cc2)C3OC(COC)CC(O3)c4ccc(NC(=O)CCCCCCC(=O)NO)cc4)c5ccc(NC(=O)CCCCCCC(=O)NO)cc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J14 mock treatment 840.0 422.0 2.8 800.0 312.0 2.03 3.4156 0.9877 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J15 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652551 HDAC1-H_000162 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CC#C)CC(O2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J16 mock treatment 520.0 102.0 0.68 600.0 112.0 0.73 0.9954 0.9992 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J17 compound treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 3652552 HDAC1-H_000163 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)OC)cc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J18 mock treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J19 compound treatment 280.0 -138.0 -0.91 320.0 -168.0 -1.09 -1.4179 -0.9962 3215583 HDAC1-H_000164 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J20 mock treatment 400.0 -18.0 -0.12 560.0 72.4 0.47 0.2489 0.5123 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J21 mock treatment 320.0 -98.0 -0.65 560.0 72.4 0.47 -0.1261 -0.1572 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J22 mock treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J23 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 3635098 HDAC1-H_000165 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 J24 mock treatment 400.0 -18.0 -0.12 680.0 192.0 1.25 0.801 0.637 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K01 compound treatment 520.0 102.0 0.68 560.0 72.4 0.47 0.8114 0.9843 3652553 HDAC1-H_000166 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K02 compound treatment 560.0 142.0 0.94 560.0 72.4 0.47 0.9989 0.9487 3652555 HDAC1-H_000167 COc1ccc(NCc2ccc(cc2)C(=O)Nc3ccccc3[N+](=O)[O-])cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K03 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652556 HDAC1-H_000168 ONC(=O)c1cn(nn1)c2cccc(c2)C(=O)NCCc3c[nH]c4ccccc34 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K04 compound treatment 560.0 142.0 0.94 600.0 112.0 0.73 1.1829 0.9922 3652557 HDAC1-H_000169 Cc1ccc(NCc2ccc(cc2)C(=O)Nc3ccccc3[N+](=O)[O-])cc1C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K05 compound treatment 440.0 22.0 0.15 640.0 152.0 0.99 0.8045 0.8027 3652558 HDAC1-H_000170 CC(C)(C)ONC(=O)c1ccc(cc1)n2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K06 compound treatment 440.0 22.0 0.15 360.0 -128.0 -0.83 -0.4838 -0.5738 3614389 HDAC1-H_000171 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K07 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K08 mock treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K09 compound treatment 400.0 -18.0 -0.12 600.0 112.0 0.73 0.4329 0.5843 3652484 HDAC1-H_000172 COc1ccc(cc1)n2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K10 compound treatment 480.0 62.0 0.41 680.0 192.0 1.25 1.176 0.8925 3614392 HDAC1-H_000173 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K11 compound treatment 560.0 142.0 0.94 400.0 -87.6 -0.57 0.2627 0.2386 3652483 HDAC1-H_000174 COc1cccc(c1)n2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K12 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3614394 HDAC1-H_000175 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K13 compound treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 3652484 HDAC1-H_000176 COc1ccc(cc1)n2cc(nn2)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K14 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3614396 HDAC1-H_000177 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K15 mock treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K16 mock treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K17 compound treatment 520.0 102.0 0.68 480.0 -7.62 -0.05 0.4433 0.6535 3652559 HDAC1-H_000178 CCOc1cc(OCC)cc(c1)C(=O)N[C@H](Cc2ccc(cc2)n3cc(nn3)C(=O)NO)C(=O)OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K18 compound treatment 480.0 62.0 0.41 720.0 232.0 1.51 1.36 0.8679 3614383 HDAC1-H_000179 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K19 compound treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 3652561 HDAC1-H_000180 COc1ccc(cc1)C(=O)Nc2cccc(c2)n3cc(nn3)C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K20 compound treatment 200.0 -218.0 -1.44 440.0 -47.6 -0.31 -1.2407 -0.8397 3614398 HDAC1-H_000181 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K21 compound treatment 360.0 -58.0 -0.38 640.0 152.0 0.99 0.4295 0.4039 3652381 HDAC1-H_000182 COC(=O)[C@@H](NC(=O)Cn1cc(CCC(=O)NO)nn1)c2ccccc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K22 compound treatment 320.0 -98.0 -0.65 560.0 72.4 0.47 -0.1261 -0.1572 3614403 HDAC1-H_000183 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K23 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 K24 mock treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L01 compound treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 3215593 HDAC1-H_000184 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L02 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L03 compound treatment 480.0 62.0 0.41 360.0 -128.0 -0.83 -0.2964 -0.3198 3635101 HDAC1-H_000185 CC(C)OCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L04 mock treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L05 compound treatment 280.0 -138.0 -0.91 480.0 -7.62 -0.05 -0.6817 -0.7443 3652562 HDAC1-H_000186 CNc1ccc(cc1)C(=O)NCCCCCCC(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L06 mock treatment 320.0 -98.0 -0.65 480.0 -7.62 -0.05 -0.4942 -0.7589 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L07 mock treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L08 mock treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L09 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652563 HDAC1-H_000187 ONC(=O)/C=C/c1ccc(CNc2ccc(cc2)C3OC(CSc4ccncc4)CC(O3)c5ccccc5)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L10 mock treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L11 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652565 HDAC1-H_000188 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(OC(O2)c3ccncc3)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L12 mock treatment 480.0 62.0 0.41 520.0 32.4 0.21 0.4398 0.9517 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L13 mock treatment 520.0 102.0 0.68 400.0 -87.6 -0.57 0.0752 0.085 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L14 mock treatment 520.0 102.0 0.68 560.0 72.4 0.47 0.8114 0.9843 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L15 mock treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L16 mock treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L17 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3635112 HDAC1-H_000189 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@H]2O[C@@H](CSc3ccncc3)C[C@H](O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L18 mock treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L19 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3215595 HDAC1-H_000190 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L20 mock treatment 320.0 -98.0 -0.65 520.0 32.4 0.21 -0.3101 -0.4543 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L21 compound treatment 560.0 142.0 0.94 520.0 32.4 0.21 0.8148 0.8445 3652566 HDAC1-H_000191 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN3CCNCC3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L22 mock treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L23 mock treatment 360.0 -58.0 -0.38 680.0 192.0 1.25 0.6135 0.4685 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 L24 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M01 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652384 HDAC1-H_000192 CC(C)[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)NCCn2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M02 compound treatment 320.0 -98.0 -0.65 320.0 -168.0 -1.09 -1.2304 -0.9693 3652567 HDAC1-H_000193 C/C(=C\c1ccccc1OCc2ccc(cc2)c3ccncc3)/C=C/C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M03 compound treatment 480.0 62.0 0.41 360.0 -128.0 -0.83 -0.2964 -0.3198 3652569 HDAC1-H_000194 COc1ccc(OC)c(NC(=O)Cn2cc(CCC(=O)NO)nn2)c1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M04 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652570 HDAC1-H_000195 C/C(=C\c1cccc(OCc2ccc(cc2)c3ccncc3)c1)/C=C/C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M05 compound treatment 600.0 182.0 1.21 560.0 72.4 0.47 1.1863 0.9158 3652572 HDAC1-H_000196 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(CCC(=O)NO)nn3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M06 compound treatment 400.0 -18.0 -0.12 400.0 -87.6 -0.57 -0.4873 -0.8367 3652574 HDAC1-H_000197 CN1C[C@H](COc2ccccc2/C=C(\C)/C=C/C(=O)NO)C=C3[C@H]1Cc4c[nH]c5cccc3c45 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M07 compound treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 3652576 HDAC1-H_000198 ONC(=O)CCc1cn(CCCNC(=O)Nc2ccccc2)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M08 compound treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 3652577 HDAC1-H_000199 C/C(=C\c1ccccc1OC[C@H]2[C@@H](O)CC[C@H]3CN4CCc5c([nH]c6ccccc56)[C@@H]4C[C@H]23)/C=C/C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M09 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M10 mock treatment 400.0 -18.0 -0.12 320.0 -168.0 -1.09 -0.8554 -0.7796 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M11 compound treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 3652579 HDAC1-H_000200 ONC(=O)CCc1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M12 compound treatment 320.0 -98.0 -0.65 440.0 -47.6 -0.31 -0.6782 -0.9427 3652581 HDAC1-H_000201 C/C(=C\c1cccc(OC[C@H]2[C@@H](O)CC[C@H]3CN4CCc5c([nH]c6ccccc56)[C@@H]4C[C@H]23)c1)/C=C/C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M13 mock treatment 440.0 22.0 0.15 640.0 152.0 0.99 0.8045 0.8027 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M14 mock treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M15 compound treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 3652583 HDAC1-H_000202 ONC(=O)CCc1cn(CCNC(=O)Nc2ccccc2)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M16 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652584 HDAC1-H_000203 CCN(CC)CCNc1ccc(COc2ccccc2/C=C(\C)/C=C/C(=O)NO)c3sc4ccccc4c(=O)c13 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M17 compound treatment 520.0 102.0 0.68 560.0 72.4 0.47 0.8114 0.9843 3652586 HDAC1-H_000204 ONC(=O)CCc1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M18 compound treatment 480.0 62.0 0.41 360.0 -128.0 -0.83 -0.2964 -0.3198 3652587 HDAC1-H_000205 CCN(CC)CCNc1ccc(COc2cccc(/C=C(\C)/C=C/C(=O)NO)c2)c3sc4ccccc4c(=O)c13 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M19 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652589 HDAC1-H_000206 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M20 compound treatment 320.0 -98.0 -0.65 440.0 -47.6 -0.31 -0.6782 -0.9427 3652591 HDAC1-H_000207 C/C(=C\c1ccccc1OCc2ccc(COc3ccc4ccncc4c3)cc2)/C=C/C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M21 compound treatment 400.0 -18.0 -0.12 480.0 -7.62 -0.05 -0.1192 -0.9247 3652593 HDAC1-H_000208 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(CCC(=O)NO)nn3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M22 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652595 HDAC1-H_000209 C/C(=C\c1cccc(OCc2ccc(COc3ccc4ccncc4c3)cc2)c1)/C=C/C(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M23 compound treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 3652597 HDAC1-H_000210 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(CCC(=O)NO)nn3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 M24 compound treatment 360.0 -58.0 -0.38 600.0 112.0 0.73 0.2454 0.2971 3562174 HDAC1-H_000211 OCc1ccc(cc1)c2ccncc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N01 compound treatment 560.0 142.0 0.94 320.0 -168.0 -1.09 -0.1054 -0.0732 3652599 HDAC1-H_000212 CNCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N02 mock treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N03 compound treatment 320.0 -98.0 -0.65 360.0 -128.0 -0.83 -1.0463 -0.9926 3652600 HDAC1-H_000213 ONC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3cccc(Cn4cc(CNc5ccc(cc5)C(=O)NCCCCCCC(=O)NO)nn4)c3)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N04 mock treatment 640.0 222.0 1.47 520.0 32.4 0.21 1.1898 0.8002 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N05 compound treatment 360.0 -58.0 -0.38 360.0 -128.0 -0.83 -0.8588 -0.9386 3634810 HDAC1-H_000214 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C(=O)c2ccc(NC(=O)CCCC#C)cc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N06 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N07 compound treatment 360.0 -58.0 -0.38 360.0 -128.0 -0.83 -0.8588 -0.9386 3652601 HDAC1-H_000215 ONC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3ccc(cc3)C(=O)c4ccc(Cn5cc(CNc6ccc(cc6)C(=O)NCCCCCCC(=O)NO)nn5)cc4)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N08 mock treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N09 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N10 mock treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N11 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 483 HDAC1-H_000216 CN(C)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N12 mock treatment 440.0 22.0 0.15 400.0 -87.6 -0.57 -0.2998 -0.5094 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N13 mock treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N14 mock treatment 520.0 102.0 0.68 560.0 72.4 0.47 0.8114 0.9843 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N15 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3652602 HDAC1-H_000217 ONC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3ccc(Cn4cc(CNc5ccc(cc5)C(=O)NCCCCCCC(=O)NO)nn4)cc3)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N16 mock treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N17 compound treatment 360.0 -58.0 -0.38 400.0 -87.6 -0.57 -0.6748 -0.9815 3652603 HDAC1-H_000218 ONC(=O)CCCCCCC(=O)Nc1ccc(/C=N/O)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N18 mock treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N19 compound treatment 400.0 -18.0 -0.12 360.0 -128.0 -0.83 -0.6713 -0.8003 468 HDAC1-H_000219 ONC(=O)CCCCCCC(=O)Nc1ccccc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N20 mock treatment 480.0 62.0 0.41 560.0 72.4 0.47 0.6239 0.9977 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N21 compound treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 3652605 HDAC1-H_000220 COC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3ccc(cc3)C(=O)c4ccc(Cn5cc(CNc6ccc(cc6)C(=O)NCCCCCCC(=O)OC)nn5)cc4)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N22 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N23 compound treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 3652606 HDAC1-H_000221 ONC(=O)CCCCCCC(=O)Nc1ccc(/C=N/OCc2ccccc2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 N24 mock treatment 440.0 22.0 0.15 400.0 -87.6 -0.57 -0.2998 -0.5094 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O01 compound treatment 520.0 102.0 0.68 640.0 152.0 0.99 1.1794 0.9826 3652608 HDAC1-H_000222 ONC(=O)CCc1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O02 compound treatment 440.0 22.0 0.15 440.0 -47.6 -0.31 -0.1158 -0.3379 3652610 HDAC1-H_000223 OC[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O03 compound treatment 480.0 62.0 0.41 480.0 -7.62 -0.05 0.2558 0.6174 3652612 HDAC1-H_000224 ONC(=O)CCc1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O04 compound treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 1105 HDAC1-H_000225 CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O05 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3652613 HDAC1-H_000226 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(CCC(=O)NO)nn3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O06 compound treatment 960.0 542.0 3.59 1120.0 632.0 4.11 5.4504 0.9977 3652615 HDAC1-H_000227 OCc1ccc(COc2ccc3ccncc3c2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O07 compound treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 3652616 HDAC1-H_000228 Cc1ccc(cc1)S(=O)(=O)N(c2cccc(c2)n3cc(CCC(=O)NO)nn3)S(=O)(=O)c4ccc(C)cc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O08 compound treatment 440.0 22.0 0.15 320.0 -168.0 -1.09 -0.6679 -0.6069 3652617 HDAC1-H_000229 ONC(=O)/C=C/c1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O09 compound treatment 440.0 22.0 0.15 480.0 -7.62 -0.05 0.0683 0.4425 3652619 HDAC1-H_000230 ONC(=O)CCc1cn(nn1)c2cccc(c2)C(=O)O 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O10 compound treatment 400.0 -18.0 -0.12 440.0 -47.6 -0.31 -0.3033 -0.9136 3652620 HDAC1-H_000231 COc1cc2CCN(CC3CC(OC(O3)c4ccc(NC(=O)CCCCCCC(=O)NO)cc4)c5ccccc5)Cc2cc1OC 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O11 mock treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O12 mock treatment 480.0 62.0 0.41 440.0 -47.6 -0.31 0.0717 0.1393 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O13 compound treatment 520.0 102.0 0.68 600.0 112.0 0.73 0.9954 0.9992 3652621 HDAC1-H_000232 CC(C)(C)ONC(=O)c1cccc(c1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O14 compound treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 3652622 HDAC1-H_000233 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O15 compound treatment 600.0 182.0 1.21 600.0 112.0 0.73 1.3704 0.9712 3652387 HDAC1-H_000234 COc1ccc(cc1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O16 compound treatment 280.0 -138.0 -0.91 440.0 -47.6 -0.31 -0.8657 -0.8966 3635093 HDAC1-H_000235 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccc3)CC(O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O17 compound treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 3652623 HDAC1-H_000236 COc1cccc(c1)n2cc(CCC(=O)NO)nn2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O18 compound treatment 520.0 102.0 0.68 520.0 32.4 0.21 0.6273 0.8854 3561878 HDAC1-H_000237 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O19 compound treatment 320.0 -98.0 -0.65 360.0 -128.0 -0.83 -1.0463 -0.9926 3652624 HDAC1-H_000238 ONC(=O)CCc1cn(nn1)c2ccc(NC(=O)c3ccccc3)cc2 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O20 compound treatment 440.0 22.0 0.15 400.0 -87.6 -0.57 -0.2998 -0.5094 3635080 HDAC1-H_000239 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O21 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 3652625 HDAC1-H_000240 ONC(=O)CCc1cn(nn1)c2cccc(c2)C(=O)N3CCC4(CC3)N(CNC4=O)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O22 compound treatment 360.0 -58.0 -0.38 360.0 -128.0 -0.83 -0.8588 -0.9386 3635109 HDAC1-H_000241 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@@H]2O[C@H](CSc3ccncc3)C[C@@H](O2)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O23 compound treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799 3652626 HDAC1-H_000242 COc1ccc(cc1)C(=O)Nc2cccc(c2)n3cc(CCC(=O)NO)nn3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 O24 compound treatment 440.0 22.0 0.15 520.0 32.4 0.21 0.2523 0.984 3215599 HDAC1-H_000243 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P01 compound treatment 320.0 -98.0 -0.65 480.0 -7.62 -0.05 -0.4942 -0.7589 3652627 HDAC1-H_000244 COC(=O)CCCCCCC(=O)Nc1ccc(/C=N/OCc2ccccc2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P02 mock treatment 360.0 -58.0 -0.38 440.0 -47.6 -0.31 -0.4907 -0.9943 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P03 compound treatment 400.0 -18.0 -0.12 320.0 -168.0 -1.09 -0.8554 -0.7796 3652629 HDAC1-H_000245 ONC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3ccccc3Cn4cc(CNc5ccc(cc5)C(=O)NCCCCCCC(=O)NO)nn4)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P04 mock treatment 480.0 62.0 0.41 320.0 -168.0 -1.09 -0.4804 -0.4121 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P05 compound treatment 440.0 22.0 0.15 320.0 -168.0 -1.09 -0.6679 -0.6069 3652630 HDAC1-H_000246 ONC(=O)CCCCCCNC(=O)c1ccc(cc1)N(CC#C)CC#C 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P06 mock treatment 440.0 22.0 0.15 400.0 -87.6 -0.57 -0.2998 -0.5094 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P07 compound treatment 400.0 -18.0 -0.12 320.0 -168.0 -1.09 -0.8554 -0.7796 3652631 HDAC1-H_000247 ONC(=O)CCCCCCNC(=O)c1ccc(NCc2cn(Cc3ccccc3)nn2)cc1 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P08 mock treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P09 compound treatment 440.0 22.0 0.15 640.0 152.0 0.99 0.8045 0.8027 3634807 HDAC1-H_000248 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(OC(O2)c3ccccc3)c4ccccc4 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P10 mock treatment 400.0 -18.0 -0.12 640.0 152.0 0.99 0.617 0.6178 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P11 mock treatment 520.0 102.0 0.68 600.0 112.0 0.73 0.9954 0.9992 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P12 mock treatment 440.0 22.0 0.15 560.0 72.4 0.47 0.4364 0.8849 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P13 compound treatment 320.0 -98.0 -0.65 400.0 -87.6 -0.57 -0.8623 -0.9979 3652632 HDAC1-H_000249 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(OC(O2)c3ccc(Oc4ccccc4)cc3)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P14 mock treatment 480.0 62.0 0.41 360.0 -128.0 -0.83 -0.2964 -0.3198 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P15 compound treatment 440.0 22.0 0.15 600.0 112.0 0.73 0.6204 0.832 3652633 HDAC1-H_000250 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(OC(O2)c3cccc(Oc4ccccc4)c3)c5ccccc5 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P16 mock treatment 480.0 62.0 0.41 520.0 32.4 0.21 0.4398 0.9517 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P17 compound treatment 480.0 62.0 0.41 520.0 32.4 0.21 0.4398 0.9517 3634674 HDAC1-H_000251 OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccc(NC(=O)CCCCCCC(=O)O)cc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P18 mock treatment 520.0 102.0 0.68 440.0 -47.6 -0.31 0.2592 0.3484 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P19 compound treatment 320.0 -98.0 -0.65 480.0 -7.62 -0.05 -0.4942 -0.7589 2027357 HDAC1-H_000252 OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)O[C@@H](O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P20 mock treatment 400.0 -18.0 -0.12 520.0 32.4 0.21 0.0648 0.2679 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P21 compound treatment 360.0 -58.0 -0.38 560.0 72.4 0.47 0.0614 0.101 3562114 HDAC1-H_000253 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P22 mock treatment 400.0 -18.0 -0.12 560.0 72.4 0.47 0.2489 0.5123 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P23 compound treatment 280.0 -138.0 -0.91 560.0 72.4 0.47 -0.3136 -0.3049 3652634 HDAC1-H_000254 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@H]2O[C@@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)C[C@H](O2)c6ccccc6 1104.0068 LuxReporter(1104.0068) wntAndLithiumModulators 1104.0068.2467 P24 mock treatment 360.0 -58.0 -0.38 520.0 32.4 0.21 -0.1227 -0.2799