ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A01 compound treatment 0.296 0.14 1.47 0.309 0.146 1.75 2.279 0.9964 3036889 ChemDiv3_013377 CCN(C(=O)CSc1ncccc1C(=O)OC(C)C)c2cccc(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A02 compound treatment 0.19 0.0344 0.36 0.203 0.0402 0.48 0.595 0.9901 3121867 ChemDiv3_013378 Cc1cccc(NC(=S)N(CCc2ccncc2)C3CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A03 compound treatment 0.11 -0.0456 -0.48 0.107 -0.0558 -0.67 -0.8113 -0.9867 3121868 ChemDiv3_013379 CC1CCCC(C)N1CCNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A04 compound treatment 0.247 0.0914 0.96 0.224 0.0612 0.73 1.196 0.991 3036891 ChemDiv3_013380 CC(C)CCNC(=O)C1CCN(CC1)C(=O)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A05 compound treatment 0.65 0.494 5.19 0.62 0.457 5.47 7.5391 0.9997 3121869 ChemDiv3_013381 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A06 compound treatment 0.213 0.0574 0.6 0.225 0.0622 0.74 0.9519 0.9946 3036894 ChemDiv3_013382 O=C(CN1N=C(CCC1=O)c2ccccc2)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A07 compound treatment 0.186 0.0304 0.32 0.189 0.0262 0.31 0.4469 1.0 3121870 ChemDiv3_013383 CCC(C)NC(=O)c1ccc(CS(=O)(=O)Cc2ccc(Cl)cc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A08 compound treatment 0.149 -0.00663 -0.07 0.134 -0.0288 -0.35 -0.2932 -0.8329 3036896 ChemDiv3_013384 O=C(NCCC1=CCCCC1)C2CCN(CC2)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A09 compound treatment 0.151 -0.00463 -0.05 0.156 -0.00684 -0.08 -0.0922 -0.9689 3121871 ChemDiv3_013385 COc1ccc(Br)cc1CNC(=O)C2CCCN(C2)c3nc4ccccc4o3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A10 compound treatment 0.64 0.484 5.09 0.628 0.465 5.57 7.5325 0.999 3036897 ChemDiv3_013386 Cc1ccc(CSCCC(=O)N2CCN(CC2)c3cccc(C)c3C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A11 compound treatment 0.137 -0.0186 -0.2 0.149 -0.0138 -0.17 -0.2554 -0.9966 3121872 ChemDiv3_013387 CC(C)CCN(C)C1CCN(CC1)S(=O)(=O)c2cccc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A12 compound treatment 0.165 0.00937 0.1 0.186 0.0232 0.28 0.2655 0.9031 3036900 ChemDiv3_013388 CS(=O)(=O)N1CCCC(C1)C(=O)NCC=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A13 compound treatment 0.179 0.0234 0.25 0.207 0.0442 0.53 0.5472 0.9392 3121873 ChemDiv3_013389 O=C(CNC(=O)c1cccs1)N2CCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A14 compound treatment 0.174 0.0184 0.19 0.161 -0.00184 -0.02 0.1209 0.6222 3121874 ChemDiv3_013390 CCS(=O)(=O)N1CCC(CC1)C(=O)N2CCc3ccccc3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A15 compound treatment 0.089 -0.0666 -0.7 0.095 -0.0678 -0.81 -1.0688 -0.9973 3036903 ChemDiv3_013391 FC(F)(F)c1cccc(c1)S(=O)(=O)N(CCCN2CCOCC2)Cc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A16 compound treatment 0.171 0.0154 0.16 0.201 0.0382 0.46 0.437 0.9024 3121875 ChemDiv3_013392 O=C(CN1C(=O)COc2ccccc12)NCCN3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A17 compound treatment 0.176 0.0204 0.21 0.203 0.0402 0.48 0.491 0.9336 3036942 ChemDiv3_013393 CCC1Oc2ccccc2N(CC(=O)N3CCOCC3)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A18 compound treatment 0.243 0.0874 0.92 0.271 0.108 1.29 1.5639 0.9858 3036943 ChemDiv3_013394 O=C(NCCc1ccccc1)C2CN(C3CCCC3)C(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A19 compound treatment 0.203 0.0474 0.5 0.228 0.0652 0.78 0.9031 0.9765 3036945 ChemDiv3_013395 O=C(CCN1C(=O)COc2ccccc12)NC3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A20 compound treatment 0.278 0.122 1.29 0.304 0.141 1.69 2.103 0.9909 3036946 ChemDiv3_013396 Cc1ccc(cc1)c2ccc(=O)n(CC(=O)N3CCCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A21 compound treatment 0.214 0.0584 0.61 0.204 0.0412 0.49 0.7817 0.9941 3036947 ChemDiv3_013397 COCCN(C1CCN(CC1)C(C)C)C(=O)Nc2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A22 compound treatment 1.114 0.958 10.07 1.107 0.944 11.3 15.1051 0.9983 3036948 ChemDiv3_013398 Cc1ccccc1CSCc2ccc(o2)C(=O)NCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A23 mock treatment 0.157 0.00137 0.01 0.2 0.0372 0.44 0.3246 0.7297 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 A24 mock treatment 0.218 0.0624 0.66 0.177 0.0142 0.17 0.583 0.8616 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B01 compound treatment 0.308 0.152 1.6 0.347 0.184 2.2 2.6896 0.9877 3036950 ChemDiv3_013399 O=C(CCn1nc(ccc1=O)c2ccccc2)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B02 compound treatment 0.256 0.1 1.05 0.23 0.0672 0.8 1.3136 0.991 3121876 ChemDiv3_013400 Brc1ccc2[nH]c(=O)cc(C(=O)NC3CCCC3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B03 compound treatment 0.19 0.0344 0.36 0.207 0.0442 0.53 0.6289 0.9828 3122060 ChemDiv3_013401 COc1ccc(CN2CC(CC2=O)C(=O)NCCCN3CCC(C)CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B04 compound treatment 0.283 0.127 1.34 0.292 0.129 1.55 2.0386 0.9974 3036953 ChemDiv3_013402 C=CCNC(=O)CN1C(=O)/C(=C/c2ccccc2)/Sc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B05 compound treatment 0.182 0.0264 0.28 0.223 0.0602 0.72 0.7048 0.9139 3122061 ChemDiv3_013403 CCC(C)NC(=O)C1CCC(=O)N1CCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B06 compound treatment 0.249 0.0934 0.98 0.255 0.0922 1.1 1.4731 0.9983 3122062 ChemDiv3_013404 CC1CCN(CC1)S(=O)(=O)c2ccc3nc(cc(C(=O)NCC4CCCO4)c3c2)c5cccnc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B07 compound treatment 0.28 0.124 1.31 0.302 0.139 1.66 2.101 0.9928 3036955 ChemDiv3_013405 CCc1ccc(Sc2cc(C(=O)NC3CC3)c4ccccc4n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B08 compound treatment 0.14 -0.0156 -0.16 0.153 -0.00984 -0.12 -0.1993 -0.9868 3036957 ChemDiv3_013406 CC(N(C1CCCCC1)C(=O)Nc2ccccc2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B09 compound treatment 0.153 -0.00263 -0.03 0.157 -0.00584 -0.07 -0.0689 -0.9172 3122063 ChemDiv3_013407 CC1CCCC(C)N1CCNC(=O)C2C3OC4(CN(Cc5ccccc5Cl)C(=O)C24)C=C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B10 compound treatment 0.823 0.667 7.01 0.854 0.691 8.27 10.8035 0.9966 3122064 ChemDiv3_013408 COC(CNC(=O)CN1C(=O)/C(=C\c2ccc(Cl)cc2)/Oc3ccc(cc13)C(C)(C)C)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B11 compound treatment 0.205 0.0494 0.52 0.237 0.0742 0.89 0.9941 0.9673 3036960 ChemDiv3_013409 CCCS(=O)(=O)N1CCC(CC1)C(=O)N2CCC3(CC2)OCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B12 compound treatment 0.211 0.0554 0.58 0.231 0.0682 0.82 0.9879 0.9863 3122065 ChemDiv3_013410 COCCN(C1CCN(CC1)C(=O)C)C(=S)Nc2cc(F)cc(F)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B13 compound treatment 0.134 -0.0216 -0.23 0.156 -0.00684 -0.08 -0.2185 -0.905 3036961 ChemDiv3_013411 CNC(=O)C1CN(CCc2ccc(C)cc2)C(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B14 compound treatment 0.182 0.0264 0.28 0.196 0.0332 0.4 0.4764 0.9846 3122066 ChemDiv3_013412 O=C(NCCC1=CCCCC1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B15 compound treatment 0.247 0.0914 0.96 0.256 0.0932 1.11 1.4667 0.9972 3036963 ChemDiv3_013413 COC(CNC(=O)c1cc(Sc2nnc(C)s2)nc3ccccc13)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B16 compound treatment 0.277 0.121 1.27 0.325 0.162 1.94 2.2733 0.9792 3122067 ChemDiv3_013414 O=C(N1CCCCC1)c2ccc(/C=C\3/Sc4ccccc4NC3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B17 compound treatment 0.174 0.0184 0.19 0.159 -0.00384 -0.05 0.1039 0.5239 3122068 ChemDiv3_013415 CN(CCNC(=O)c1cc(Sc2nnc(C)s2)nc3ccccc13)Cc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B18 compound treatment 0.256 0.1 1.05 0.307 0.144 1.72 1.965 0.9721 3036966 ChemDiv3_013416 Fc1cccc(Cl)c1CN2N=C(CCC2=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B19 compound treatment 0.287 0.131 1.38 0.306 0.143 1.71 2.1868 0.9943 3122069 ChemDiv3_013417 COc1ccc(cc1)C2=NN(CC(=O)NCc3ccc(C)cc3)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B20 compound treatment 0.552 0.396 4.16 0.525 0.362 4.33 6.0076 0.9998 3036967 ChemDiv3_013418 COc1ccccc1NC(=S)N(Cc2cccn2Cc3ccc(F)cc3Cl)Cc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B21 compound treatment 0.648 0.492 5.17 0.691 0.528 6.32 8.1249 0.995 3036915 ChemDiv3_013419 CSc1cccc(NC(=S)NCc2cccn2C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B22 compound treatment 0.264 0.108 1.14 0.291 0.128 1.53 1.8891 0.9892 3036916 ChemDiv3_013420 COc1ccc(cc1)c2ccc(=O)n(CC(=O)N(C)c3ccccc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B23 mock treatment 0.159 0.00337 0.04 0.181 0.0182 0.22 0.1787 0.8118 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 B24 mock treatment 0.151 -0.00463 -0.05 0.158 -0.00484 -0.06 -0.0753 -0.9961 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C01 compound treatment 0.137 -0.0186 -0.2 0.163 1.56E-4 0.0 -0.137 -0.7003 3036918 ChemDiv3_013421 COc1ccc(NC(=O)CSc2ncccc2C(=O)Oc3ccccc3Cl)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C02 compound treatment 0.226 0.0704 0.74 0.196 0.0332 0.4 0.8031 0.9574 3036919 ChemDiv3_013422 CCc1ccc(NC(=O)N(CCN(C)C)C(C)c2cccnc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C03 compound treatment 0.209 0.0534 0.56 0.205 0.0422 0.5 0.753 0.9986 3036920 ChemDiv3_013423 COc1ccc(CCNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C04 compound treatment 0.187 0.0314 0.33 0.213 0.0502 0.6 0.6573 0.9602 3036923 ChemDiv3_013424 CN(C)C(=O)N1CCC(CC1)C(=O)NCCC2=CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C05 compound treatment 0.207 0.0514 0.54 0.256 0.0932 1.11 1.1697 0.9446 3122070 ChemDiv3_013425 CCC(C)NC(=O)C1CCCN(C1)S(=O)(=O)N2CCC(C)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C06 compound treatment 0.199 0.0434 0.46 0.185 0.0222 0.27 0.5096 0.9668 3036970 ChemDiv3_013426 CC(C)CCNC(=O)Cn1nc(ccc1=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C07 compound treatment 0.225 0.0694 0.73 0.235 0.0722 0.86 1.1257 0.9964 3036971 ChemDiv3_013427 Clc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C08 compound treatment 0.176 0.0204 0.21 0.182 0.0192 0.23 0.3134 0.9994 3036973 ChemDiv3_013428 O=C(Cn1nc(ccc1=O)c2ccccc2)NCCCN3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C09 compound treatment 0.279 0.123 1.3 0.293 0.13 1.56 2.0174 0.9958 3036974 ChemDiv3_013429 Cc1ccc(Cl)cc1N2CCN(CC2)C(=O)CN3C(=O)COc4ccc(cc34)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C10 compound treatment 0.699 0.543 5.71 0.767 0.604 7.23 9.1466 0.9932 3036976 ChemDiv3_013430 COc1ccc(CNC(=O)CCSCc2ccc(C)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C11 compound treatment 0.438 0.282 2.97 0.522 0.359 4.3 5.1356 0.9836 3036978 ChemDiv3_013431 Clc1cccc(CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)NCC=C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C12 compound treatment 0.321 0.165 1.74 0.315 0.152 1.82 2.5154 0.9997 3122071 ChemDiv3_013432 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)NCc2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C13 compound treatment 0.166 0.0104 0.11 0.191 0.0282 0.34 0.3153 0.8904 3036981 ChemDiv3_013433 Clc1ccc(NC(=O)N(CCCN2CCOCC2)Cc3cccnc3)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C14 compound treatment 0.226 0.0704 0.74 0.221 0.0582 0.7 1.0147 0.9995 3122072 ChemDiv3_013434 CC1CCN(CC1)C(=O)CN2N=C(CCC2=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C15 compound treatment 0.101 -0.0546 -0.57 0.096 -0.0668 -0.8 -0.9712 -0.9867 3036984 ChemDiv3_013435 O=S(=O)(N(CCCN1CCOCC1)Cc2cccs2)c3ccc(cc3)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C16 compound treatment 0.206 0.0504 0.53 0.228 0.0652 0.78 0.9253 0.9822 3122073 ChemDiv3_013436 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)N2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C17 compound treatment 0.147 -0.00863 -0.09 0.188 0.0252 0.3 0.1488 0.4733 3036987 ChemDiv3_013437 O=C(C1CCN(CC1)S(=O)(=O)N2CCCCC2)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C18 compound treatment 0.169 0.0134 0.14 0.181 0.0182 0.22 0.2529 0.9777 3122074 ChemDiv3_013438 COc1ccc(CNC(=O)C2CN(C3CCCC3)C(=O)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C19 compound treatment 0.141 -0.0146 -0.15 0.157 -0.00584 -0.07 -0.1581 -0.9365 3122075 ChemDiv3_013439 COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(cc23)S(=O)(=O)N4CCCCC4C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C20 compound treatment 0.234 0.0784 0.82 0.25 0.0872 1.04 1.3194 0.9931 3036991 ChemDiv3_013440 CCC(C)NC(=O)CN1C(=O)C(CC)Sc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C21 compound treatment 0.125 -0.0306 -0.32 0.159 -0.00384 -0.05 -0.26 -0.8001 3122076 ChemDiv3_013441 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)N2CCN(Cc3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C22 compound treatment 0.38 0.224 2.36 0.268 0.105 1.26 2.556 0.9568 3037682 ChemDiv3_013442 CCc1ccc(NC(=O)N(Cc2ccco2)C(C)c3cccs3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C23 mock treatment 0.164 0.00837 0.09 0.149 -0.0138 -0.17 -0.0549 -0.2929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 C24 mock treatment 0.173 0.0174 0.18 0.179 0.0162 0.19 0.2657 0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D01 compound treatment 0.235 0.0794 0.83 0.255 0.0922 1.1 1.3691 0.9905 3122077 ChemDiv3_013443 CC(C)NC(=O)CCn1nc(ccc1=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D02 compound treatment 0.177 0.0214 0.22 0.201 0.0382 0.46 0.4815 0.9466 3037687 ChemDiv3_013444 Cc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(Br)cc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D03 compound treatment 0.301 0.145 1.53 0.228 0.0652 0.78 1.6309 0.9513 3122078 ChemDiv3_013445 Clc1ccc(cc1)c2ccc(=O)n(CCC(=O)NCc3cccnc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D04 compound treatment 0.29 0.134 1.41 0.373 0.21 2.51 2.7759 0.9627 3037691 ChemDiv3_013446 COCCN(C(C)c1ccccn1)C(=S)Nc2cccc(Cl)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D05 compound treatment 0.226 0.0704 0.74 0.203 0.0402 0.48 0.8624 0.9782 3122079 ChemDiv3_013447 CC1CCN(CCCNC(=O)C2CN(CCc3ccccc3)C(=O)C2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D06 compound treatment 0.068 -0.0876 -0.92 0.074 -0.0888 -1.06 -1.4024 -0.9974 3037758 ChemDiv3_013448 CC(N(C1CCCCC1)C(=S)Nc2cccc(Cl)c2C)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D07 compound treatment 0.493 0.337 3.54 0.496 0.333 3.99 5.3241 0.9983 3122080 ChemDiv3_013449 CCc1ccc(Sc2cc(C(=O)NCC3CCCO3)c4ccccc4n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D08 compound treatment 0.523 0.367 3.86 0.618 0.455 5.45 6.579 0.9858 3037763 ChemDiv3_013450 Cc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)N3CCN(CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D09 compound treatment 0.44 0.284 2.99 0.418 0.255 3.05 4.2706 0.9999 3122081 ChemDiv3_013451 CC1CCCC(NC(=O)c2ccc(N3CCCCC3)c(NS(=O)(=O)c4ccc(C)cc4)c2)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D10 compound treatment 0.283 0.127 1.34 0.297 0.134 1.61 2.0809 0.9959 3037767 ChemDiv3_013452 COc1ccc(cc1)N2CCC(CNC(=O)Nc3ccccc3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D11 compound treatment 0.272 0.116 1.22 0.305 0.142 1.7 2.0669 0.9869 3122082 ChemDiv3_013453 CC1CCC(CC1)NC(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D12 compound treatment 0.228 0.0724 0.76 0.243 0.0802 0.96 1.2156 0.9934 3122083 ChemDiv3_013454 COCCN(C1CCN(CC1)C(=O)C)C(=O)Nc2ccc(OC)cc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D13 compound treatment 0.201 0.0454 0.48 0.243 0.0802 0.96 1.0151 0.9479 3037774 ChemDiv3_013455 CC(C)CCN1CC(CC1=O)C(=O)NCc2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D14 compound treatment 0.214 0.0584 0.61 0.219 0.0562 0.67 0.9086 0.999 3036687 ChemDiv3_013456 CN(CCC#N)C(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D15 compound treatment 0.375 0.219 2.3 0.411 0.248 2.97 3.7286 0.9921 3122084 ChemDiv3_013457 Cc1nnc(Sc2cc(C(=O)NCc3ccccn3)c4ccccc4n2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D16 compound treatment 0.194 0.0384 0.4 0.196 0.0332 0.4 0.5655 1.0 3036693 ChemDiv3_013458 O=C(NC1CCCC1)c2ccc(/C=C\3/Sc4ccccc4NC3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D17 compound treatment 0.147 -0.00863 -0.09 0.141 -0.0218 -0.26 -0.2489 -0.8997 3122085 ChemDiv3_013459 CC1CC(C)CN(CCCNC(=O)c2cc(Sc3nnc(C)s3)nc4ccccc24)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D18 compound treatment 0.316 0.16 1.68 0.357 0.194 2.32 2.8336 0.9875 3036698 ChemDiv3_013460 CN(C(=O)CN1N=C(CCC1=O)c2ccc(Cl)cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D19 compound treatment 0.154 -0.00163 -0.02 0.181 0.0182 0.22 0.1415 0.6496 3122264 ChemDiv3_013461 COC(CNC(=O)c1ccc2n(cnc2c1)C3CCCCCC3)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D20 compound treatment 0.283 0.127 1.34 0.317 0.154 1.84 2.2501 0.9876 3122265 ChemDiv3_013462 CC1CCCCC1NC(=O)c2ccc(/C=C\3/Sc4ccccc4NC3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D21 compound treatment 0.677 0.521 5.48 0.723 0.56 6.7 8.611 0.995 3036703 ChemDiv3_013463 CCOc1ccccc1NC(=S)NCc2cccn2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D22 compound treatment 0.198 0.0424 0.45 0.181 0.0182 0.22 0.4683 0.9456 3122266 ChemDiv3_013464 CCc1ccc(NC(=O)Cn2nc(ccc2=O)c3ccc(OC)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D23 mock treatment 0.153 -0.00263 -0.03 0.164 0.00116 0.01 -0.0097 -0.3149 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 D24 mock treatment 0.139 -0.0166 -0.17 0.148 -0.0148 -0.18 -0.249 -1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E01 compound treatment 0.498 0.342 3.6 0.418 0.255 3.05 4.7013 0.9967 3036776 ChemDiv3_013465 CCCN(CCC)C(=O)CSc1ncccc1C(=O)Oc2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E02 compound treatment 0.048 -0.108 -1.13 0.048 -0.115 -1.37 -1.7709 -0.9953 3036779 ChemDiv3_013466 CC(C)N(C(C)c1ccccn1)C(=S)Nc2cccc(c2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E03 compound treatment 0.784 0.628 6.6 0.745 0.582 6.97 9.5918 0.9996 3122267 ChemDiv3_013467 CC(=O)Nc1cc(ccc1Sc2ccc(C)cc2)C(=O)NCCc3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E04 compound treatment 0.211 0.0554 0.58 0.236 0.0732 0.88 1.0302 0.9803 3122268 ChemDiv3_013468 CCC1Oc2ccc(C)cc2N(CC(=O)NCCCN3CCN(CC3)c4ccccc4F)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E05 compound treatment 0.578 0.422 4.44 0.577 0.414 4.96 6.6406 0.9985 3036783 ChemDiv3_013469 CC1CC(C)CN(C1)C(=O)c2ccc(Sc3ccc(Cl)cc3)c(NC(=O)C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E06 compound treatment 0.286 0.13 1.37 0.248 0.0852 1.02 1.6887 0.9894 3122269 ChemDiv3_013470 O=C(Cn1nc(ccc1=O)c2ccccc2)NCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E07 compound treatment 0.542 0.386 4.06 0.521 0.358 4.29 5.8995 0.9996 3122270 ChemDiv3_013471 CCOC(=O)c1cccnc1SCC(=O)Nc2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E08 compound treatment 0.202 0.0464 0.49 0.215 0.0522 0.62 0.7857 0.9925 3036789 ChemDiv3_013472 CCS(=O)(=O)N1CCC(CC1)C(=O)NC2CCCCC2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E09 compound treatment 0.31 0.154 1.62 0.354 0.191 2.29 2.7637 0.9858 3122271 ChemDiv3_013473 COc1ccc(CCNC(=O)CCCc2cn(C)c3ccccc23)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E10 compound treatment 0.705 0.549 5.77 0.688 0.525 6.28 8.5228 0.9991 3036860 ChemDiv3_013474 Cc1ccc(CNC(=O)CCSCc2ccc(C)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E11 compound treatment 0.076 -0.0796 -0.84 0.072 -0.0908 -1.09 -1.3599 -0.9916 3036863 ChemDiv3_013475 Sc1ncccc1C(=O)n2ccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E12 compound treatment 0.173 0.0174 0.18 0.18 0.0172 0.21 0.2742 0.9983 3036865 ChemDiv3_013476 CS(=O)(=O)N1CCCC(C1)C(=O)N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E13 compound treatment 0.161 0.00537 0.06 0.185 0.0222 0.27 0.2274 0.8389 3122272 ChemDiv3_013477 CCOc1ccc(NC(=O)N(CCCN2CCOCC2)Cc3cccnc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E14 compound treatment 0.177 0.0214 0.22 0.182 0.0192 0.23 0.3208 0.9999 3036868 ChemDiv3_013478 C=CCNC(=O)CN1N=C(CCC1=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E15 compound treatment 0.233 0.0774 0.81 0.247 0.0842 1.01 1.2866 0.9944 3122273 ChemDiv3_013479 CCc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)N3CCCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E16 compound treatment 0.271 0.115 1.21 0.254 0.0912 1.09 1.628 0.9986 3122274 ChemDiv3_013480 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)N2CCc3ccccc3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E17 compound treatment 0.106 -0.0496 -0.52 0.114 -0.0488 -0.58 -0.7818 -0.9984 3036873 ChemDiv3_013481 CC1CCN(CCCNC(=O)c2ccc3n(cnc3c2)C4CCCC4)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E18 compound treatment 0.249 0.0934 0.98 0.262 0.0992 1.19 1.5323 0.9955 3122275 ChemDiv3_013482 Fc1ccc(CSCC(=O)NC2CCCCC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E19 compound treatment 0.079 -0.0766 -0.8 0.074 -0.0888 -1.06 -1.3207 -0.9906 3036925 ChemDiv3_013483 COCCN(C1CCN(CC1)C(C)C)C(=S)Nc2ccc(cc2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E20 compound treatment 0.169 0.0134 0.14 0.154 -0.00884 -0.11 0.0245 0.1394 3122276 ChemDiv3_013484 CC1CCCCN1CCNC(=O)Cn2nc(ccc2=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E21 compound treatment 0.557 0.401 4.22 0.529 0.366 4.38 6.0785 0.9998 3036929 ChemDiv3_013485 CCOC(=O)N1CCC(CC1)N(CCOC)C(=S)Nc2ccc(C)cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E22 compound treatment 0.199 0.0434 0.46 0.179 0.0162 0.19 0.4588 0.9271 3122277 ChemDiv3_013486 CC1CCN(CC1)C(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E23 mock treatment 0.157 0.00137 0.01 0.15 -0.0128 -0.15 -0.0984 -0.6378 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 E24 mock treatment 0.155 -6.25E-4 -0.01 0.153 -0.00984 -0.12 -0.0879 -0.7454 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F01 compound treatment 0.177 0.0214 0.22 0.188 0.0252 0.3 0.3716 0.9896 3122278 ChemDiv3_013487 CC1CCCN(CCCNC(=O)CCn2nc(ccc2=O)c3ccccc3)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F02 compound treatment 0.224 0.0684 0.72 0.214 0.0512 0.61 0.9406 0.9968 3036935 ChemDiv3_013488 COC(CNC(=O)c1cc(=O)[nH]c2ccc(Br)cc12)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F03 compound treatment 0.337 0.181 1.9 0.33 0.167 2.0 2.7611 0.9997 3122279 ChemDiv3_013489 Clc1ccc(cc1)c2ccc(=O)n(CCC(=O)N3CCC4(CC3)OCCO4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F04 compound treatment 0.124 -0.0316 -0.33 0.145 -0.0178 -0.21 -0.3858 -0.9772 3036938 ChemDiv3_013490 COc1cc(Cl)c(C)cc1NC(=S)N(CCN(C)C)C(C)c2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F05 compound treatment 0.219 0.0634 0.67 0.237 0.0742 0.89 1.098 0.99 3122280 ChemDiv3_013491 O=C(NC1CCCC1)C2CN(CCc3ccccc3)C(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F06 compound treatment 0.117 -0.0386 -0.41 0.122 -0.0408 -0.49 -0.6324 -0.9957 3039062 ChemDiv3_013492 O=C(NC1CC1)/C=C/2\Sc3ccccc3NC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F07 compound treatment 0.375 0.219 2.3 0.394 0.231 2.77 3.5848 0.9959 3039063 ChemDiv3_013493 CCc1ccc(Sc2cc(C(=O)NCc3cccnc3)c4ccccc4n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F08 compound treatment 0.625 0.469 4.93 0.586 0.423 5.06 7.0658 0.9999 3039064 ChemDiv3_013494 COC(CNC(=O)c1cc(nc2ccc(cc12)S(=O)(=O)N3CCC(C)CC3)c4ccccn4)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F09 compound treatment 0.171 0.0154 0.16 0.177 0.0142 0.17 0.2339 0.9997 3039065 ChemDiv3_013495 CNC(=O)C1CN(C2CCCCCC2)C(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F10 compound treatment 0.46 0.304 3.2 0.55 0.387 4.63 5.5358 0.9836 3039066 ChemDiv3_013496 Fc1ccc(cc1)N2CCN(CC2)C(=O)CN3C(=O)/C(=C/c4ccccc4F)/Sc5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F11 compound treatment 0.098 -0.0576 -0.61 0.096 -0.0668 -0.8 -0.9935 -0.9905 3039067 ChemDiv3_013497 CC1CCN(CCCNC(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(Cl)cc3)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F12 compound treatment 0.215 0.0594 0.62 0.224 0.0612 0.73 0.9583 0.9968 3122281 ChemDiv3_013498 CC(C)CCN(C(C)c1ccncc1)C(=S)Nc2ccccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F13 compound treatment 0.211 0.0554 0.58 0.213 0.0502 0.6 0.8356 0.9999 3122282 ChemDiv3_013499 CC(C)NC(=O)C1CCC(=O)N1Cc2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F14 compound treatment 0.223 0.0674 0.71 0.23 0.0672 0.8 1.0685 0.998 3039068 ChemDiv3_013500 CCC(C)NC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F15 compound treatment 0.278 0.122 1.29 0.301 0.138 1.65 2.0776 0.9923 3122283 ChemDiv3_013501 Cc1nnc(Sc2cc(C(=O)NCCc3ccccc3)c4ccccc4n2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F16 compound treatment 0.124 -0.0316 -0.33 0.16 -0.00284 -0.03 -0.2589 -0.7755 3039069 ChemDiv3_013502 CNC(=O)c1ccc(/C=C\2/Sc3ccccc3NC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F17 compound treatment 0.206 0.0504 0.53 0.222 0.0592 0.71 0.8746 0.9897 3122284 ChemDiv3_013503 Fc1ccc(CN2C(CCC2=O)C(=O)NCc3ccccc3Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F18 compound treatment 0.179 0.0234 0.25 0.157 -0.00584 -0.07 0.1242 0.4864 3122285 ChemDiv3_013504 Clc1ccc(CNC(=O)C2CCC(CNS(=O)(=O)c3ccc(Cl)cc3)CC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F19 compound treatment 0.161 0.00537 0.06 0.179 0.0162 0.19 0.1766 0.877 3039070 ChemDiv3_013505 Clc1ccc(CCNC(=O)c2cc(=O)[nH]c3ccc(Br)cc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F20 compound treatment 0.086 -0.0696 -0.73 0.099 -0.0638 -0.76 -1.0572 -0.9998 3122286 ChemDiv3_013506 Clc1cccc(NC(=S)N2CCCN(Cc3ccccc3Cl)C2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F21 compound treatment 0.117 -0.0386 -0.41 0.142 -0.0208 -0.25 -0.4632 -0.9727 3039071 ChemDiv3_013507 CCc1cccc(NC(=S)N2CCC(C2)c3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F22 compound treatment 0.281 0.125 1.32 0.299 0.136 1.63 2.083 0.9944 3122287 ChemDiv3_013508 COc1ccc(CCNC(=O)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F23 mock treatment 0.162 0.00637 0.07 0.228 0.0652 0.78 0.5986 0.765 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 F24 mock treatment 0.151 -0.00463 -0.05 0.161 -0.00184 -0.02 -0.0499 -0.9362 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G01 compound treatment 0.145 -0.0106 -0.11 0.154 -0.00884 -0.11 -0.1537 -0.9996 3122288 ChemDiv3_013509 CC(C)N1C(CCC1=O)C(=O)NCCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G02 compound treatment 0.168 0.0124 0.13 0.192 0.0292 0.35 0.3386 0.9095 3039072 ChemDiv3_013510 CS(=O)(=O)N1CCC(CC1)C(=O)NC2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G03 compound treatment 0.404 0.248 2.61 0.339 0.176 2.11 3.3349 0.9944 3122289 ChemDiv3_013511 CCc1ccc(CNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G04 compound treatment 0.215 0.0594 0.62 0.237 0.0742 0.89 1.0683 0.9851 3039073 ChemDiv3_013512 CC(C)CCN1CC(CC1=O)C(=O)NC2CCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G05 compound treatment 0.88 0.724 7.61 0.847 0.684 8.19 11.1676 0.9993 3122290 ChemDiv3_013513 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)N3CCc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G06 compound treatment 0.188 0.0324 0.34 0.174 0.0112 0.13 0.3348 0.9166 3039074 ChemDiv3_013514 O=C(Cn1nc(ccc1=O)c2ccccc2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G07 compound treatment 0.579 0.423 4.45 0.228 0.0652 0.78 3.6954 0.8186 3122291 ChemDiv3_013515 CSc1cccc(NC(=O)CSc2ncccc2C(=O)OC(C)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G08 compound treatment 0.192 0.0364 0.38 0.208 0.0452 0.54 0.6522 0.9856 3039075 ChemDiv3_013516 CCC(C)NC(=O)C1CCN(CC1)S(=O)(=O)CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G09 compound treatment 0.051 -0.105 -1.1 0.053 -0.11 -1.31 -1.7063 -0.996 3122480 ChemDiv3_013517 CC(C)N(C1CCN(CC1)C(C)C)C(=S)Nc2cc(Cl)ccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G10 compound treatment 0.687 0.531 5.58 0.773 0.61 7.3 9.1083 0.9912 3122481 ChemDiv3_013518 COc1ccccc1NC(=S)N(C(C)c2ccco2)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G11 compound treatment 0.602 0.446 4.69 0.644 0.481 5.76 7.3857 0.9948 3039076 ChemDiv3_013519 CC1CC(C)CN(C1)C(=O)c2cc(nc3ccc(cc23)S(=O)(=O)N4CCOCC4)c5ccccn5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G12 compound treatment 0.131 -0.0246 -0.26 0.144 -0.0188 -0.23 -0.3423 -0.9977 3122482 ChemDiv3_013520 CC1CC(C)CN(C1)S(=O)(=O)N2CCCC(C2)C(=O)NCCN3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G13 compound treatment 0.18 0.0244 0.26 0.161 -0.00184 -0.02 0.1654 0.6438 3122483 ChemDiv3_013521 CCc1ccc(NC(=O)N(Cc2ccco2)Cc3cccnc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G14 compound treatment 0.206 0.0504 0.53 0.214 0.0512 0.61 0.8069 0.9974 3039077 ChemDiv3_013522 CC1CCCCC1NC(=O)CN2N=C(CCC2=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G15 compound treatment 0.082 -0.0736 -0.77 0.083 -0.0798 -0.96 -1.2223 -0.9945 3122484 ChemDiv3_013523 COc1ccc(CCN(Cc2ccccn2)S(=O)(=O)c3ccc(cc3)C(C)(C)C)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G16 compound treatment 0.231 0.0754 0.79 0.277 0.114 1.37 1.5256 0.9664 3039078 ChemDiv3_013524 COc1cccc(CNC(=O)CCS(=O)(=O)Cc2ccc(C)cc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G17 compound treatment 0.082 -0.0736 -0.77 0.08 -0.0828 -0.99 -1.2476 -0.9925 3122485 ChemDiv3_013525 CCOC(=O)N1CCN(CC1)C(=O)c2ccc3n(cnc3c2)C4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G18 compound treatment 0.102 -0.0536 -0.56 0.089 -0.0738 -0.88 -1.023 -0.9764 3039079 ChemDiv3_013526 Cc1ccc(CSCC(=O)N2CCN(CC2)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G19 compound treatment 0.198 0.0424 0.45 0.23 0.0672 0.8 0.8828 0.9612 3122486 ChemDiv3_013527 CCOC(=O)N1CCN(CC1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G20 compound treatment 0.465 0.309 3.25 0.511 0.348 4.17 5.243 0.9925 3122487 ChemDiv3_013528 Cc1ccc(CSCc2ccc(o2)C(=O)NCCc3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G21 compound treatment 0.234 0.0784 0.82 0.231 0.0682 0.82 1.1587 1.0 3039080 ChemDiv3_013529 CCOc1ccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)C)cc1OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G22 compound treatment 0.273 0.117 1.23 0.248 0.0852 1.02 1.5921 0.9955 3122488 ChemDiv3_013530 Clc1ccc(cc1)c2ccc(=O)n(CC(=O)NCc3ccco3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G23 mock treatment 0.149 -0.00663 -0.07 0.152 -0.0108 -0.13 -0.1409 -0.9573 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 G24 mock treatment 0.147 -0.00863 -0.09 0.157 -0.00584 -0.07 -0.1135 -0.9918 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H01 compound treatment 0.22 0.0644 0.68 0.203 0.0402 0.48 0.8178 0.986 3039081 ChemDiv3_013531 O=C(CCn1nc(ccc1=O)c2ccccc2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H02 compound treatment 0.187 0.0314 0.33 0.178 0.0152 0.18 0.3612 0.9604 3122489 ChemDiv3_013532 CC(NC(=O)c1cc(=O)[nH]c2ccc(Br)cc12)c3ccc4OCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H03 compound treatment 0.385 0.229 2.41 0.456 0.293 3.51 4.1836 0.9832 3039082 ChemDiv3_013533 CCOC(=O)N1CCN(CC1)C(=O)CCn2nc(ccc2=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H04 compound treatment 0.179 0.0234 0.25 0.216 0.0532 0.64 0.6233 0.9143 3122490 ChemDiv3_013534 COc1ccc(cc1)N2CCC(CNS(=O)(=O)c3cccc(c3)C(F)(F)F)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H05 compound treatment 0.205 0.0494 0.52 0.248 0.0852 1.02 1.0871 0.9509 3122491 ChemDiv3_013535 CC1CCCC(C)N1CCNC(=O)CCn2nc(ccc2=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H06 compound treatment 0.191 0.0354 0.37 0.198 0.0352 0.42 0.5601 0.9981 3039083 ChemDiv3_013536 O=C(/C=C/1\Sc2ccccc2NC1=O)N3CCN(CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H07 compound treatment 0.35 0.194 2.04 0.374 0.211 2.53 3.2299 0.9944 3122492 ChemDiv3_013537 CCOc1ccc(Sc2cc(C(=O)N3CCCC3)c4ccccc4n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H08 compound treatment 0.37 0.214 2.25 0.411 0.248 2.97 3.6915 0.9907 3122493 ChemDiv3_013538 CC1CCN(CC1)S(=O)(=O)c2ccc3nc(cc(C(=O)NC4CCCC4)c3c2)c5ccccn5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H09 compound treatment 0.15 -0.00563 -0.06 0.182 0.0192 0.23 0.1203 0.5082 3039084 ChemDiv3_013539 CCS(=O)(=O)N1CCCC(C1)C(=O)NCc2cccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H10 compound treatment 0.391 0.235 2.47 0.403 0.24 2.87 3.7798 0.9972 3122494 ChemDiv3_013540 NC(=O)C1CCN(CC1)C(=O)CN2C(=O)/C(=C/c3ccccc3F)/Sc4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H11 compound treatment 0.137 -0.0186 -0.2 0.139 -0.0238 -0.29 -0.34 -0.9831 3039085 ChemDiv3_013541 O=C(NCCCN1CCCC1=O)c2ccc3n(cnc3c2)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H12 compound treatment 0.16 0.00437 0.05 0.198 0.0352 0.42 0.3299 0.7797 3122495 ChemDiv3_013542 COc1ccc(cc1)C2=NN(CCC(=O)NC3CC3)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H13 compound treatment 0.285 0.129 1.36 0.313 0.15 1.8 2.2311 0.9905 3039086 ChemDiv3_013543 CCc1cccc(NC(=S)N(CCC(C)C)C(C)c2cccs2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H14 compound treatment 0.285 0.129 1.36 0.325 0.162 1.94 2.3327 0.9848 3122496 ChemDiv3_013544 O=C(C1CCC(CNS(=O)(=O)c2ccccc2)CC1)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H15 compound treatment 0.244 0.0884 0.93 0.249 0.0862 1.03 1.3852 0.9986 3122497 ChemDiv3_013545 Cc1nnc(Sc2cc(C(=O)NC3CC3)c4ccccc4n2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H16 compound treatment 0.13 -0.0256 -0.27 0.151 -0.0118 -0.14 -0.2905 -0.9551 3039087 ChemDiv3_013546 CCc1cccc(NC(=S)N(C)Cc2cn(C)c3ccccc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H17 compound treatment 0.474 0.318 3.34 0.507 0.344 4.12 5.276 0.9947 3122498 ChemDiv3_013547 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)NC3CCCCC3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H18 compound treatment 0.114 -0.0416 -0.44 0.112 -0.0508 -0.61 -0.7393 -0.9869 3039088 ChemDiv3_013548 CSc1cccc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H19 compound treatment 0.187 0.0314 0.33 0.239 0.0762 0.91 0.8773 0.9054 3122499 ChemDiv3_013549 Cc1cccc(CCNC(=O)c2cc(O)nc3ccc(Br)cc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H20 compound treatment 0.409 0.253 2.66 0.459 0.296 3.54 4.3872 0.99 3122500 ChemDiv3_013550 CC(C)c1ccc(NC(=O)CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)N5CCCC5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H21 compound treatment 0.114 -0.0416 -0.44 0.12 -0.0428 -0.51 -0.6716 -0.9969 3039089 ChemDiv3_013551 CCC1=Nc2cc(ccc2Sc3ccc(C)cc13)C(=O)NCCN4CCCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H22 compound treatment 0.145 -0.0106 -0.11 0.16 -0.00284 -0.03 -0.103 -0.8826 3122501 ChemDiv3_013552 O=C(NCCC1=CCCCC1)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H23 mock treatment 0.185 0.0294 0.31 0.179 0.0162 0.19 0.3548 0.9746 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 H24 mock treatment 0.147 -0.00863 -0.09 0.153 -0.00984 -0.12 -0.1473 -0.9916 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I01 compound treatment 0.122 -0.0336 -0.35 0.123 -0.0398 -0.48 -0.5868 -0.9891 3039090 ChemDiv3_013553 CN(C)CCNC(=O)c1ccc(Sc2ccc(Cl)cc2)c(NC(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I02 compound treatment 0.264 0.108 1.14 0.208 0.0452 0.54 1.1869 0.942 3122502 ChemDiv3_013554 CS(=O)(=O)N1CCC(CC1)C(=O)N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I03 compound treatment 0.256 0.1 1.05 0.299 0.136 1.63 1.8973 0.9778 3122503 ChemDiv3_013555 CCC1Oc2ccc(Cl)cc2N(CC(=O)NCCc3ccccc3)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I04 compound treatment 0.235 0.0794 0.83 0.216 0.0532 0.64 1.0392 0.9911 3039091 ChemDiv3_013556 CN(C)C(=O)N1CCCC(C1)C(=O)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I05 compound treatment 0.382 0.226 2.38 0.396 0.233 2.79 3.6537 0.9968 3122504 ChemDiv3_013557 CCCCN(C)C(=O)c1ccc(Sc2ccc(Cl)cc2)c(NC(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I06 compound treatment 0.33 0.174 1.83 0.3 0.137 1.64 2.4554 0.9985 3039092 ChemDiv3_013558 COc1ccc(CNC(=O)Cn2nc(ccc2=O)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I07 compound treatment 0.832 0.676 7.1 0.842 0.679 8.13 10.7689 0.9978 3122505 ChemDiv3_013559 CC(C)OC(=O)c1cccnc1SCc2cc(=O)n3ccccc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I08 compound treatment 0.164 0.00837 0.09 0.18 0.0172 0.21 0.2073 0.9285 3122506 ChemDiv3_013560 CCS(=O)(=O)N1CCC(CC1)C(=O)NCc2ccc(F)cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I09 compound treatment 0.041 -0.115 -1.2 0.042 -0.121 -1.45 -1.8736 -0.9959 3039093 ChemDiv3_013561 COc1ccc(NC(=S)N(C(C)C)C2CCN(CC2)C(C)C)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I10 compound treatment 0.206 0.0504 0.53 0.244 0.0812 0.97 1.0607 0.9592 3122688 ChemDiv3_013562 CC(N(C1CCCCC1)C(=O)Nc2ccccc2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I11 compound treatment 0.189 0.0334 0.35 0.209 0.0462 0.55 0.6383 0.9759 3039094 ChemDiv3_013563 O=C(CNC(=O)c1cccs1)NCc2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I12 compound treatment 0.351 0.195 2.05 0.359 0.196 2.35 3.1105 0.9978 3122689 ChemDiv3_013564 COc1ccc(OC)c(CNC(=O)C2CCCN(C2)S(=O)(=O)N3CC(C)CC(C)C3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I13 compound treatment 0.185 0.0294 0.31 0.259 0.0962 1.15 1.0316 0.8661 3122690 ChemDiv3_013565 COc1ccc(NC(=O)N(Cc2ccc(C)cc2)Cc3ccccn3)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I14 compound treatment 0.28 0.124 1.31 0.354 0.191 2.29 2.5409 0.9647 3039095 ChemDiv3_013566 O=C(CN1C(=O)COc2ccccc12)NCc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I15 compound treatment 0.092 -0.0636 -0.67 0.096 -0.0668 -0.8 -1.038 -0.996 3122691 ChemDiv3_013567 O=C(NCCC1=CCCCC1)c2ccc3n(cnc3c2)C4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I16 compound treatment 0.59 0.434 4.56 0.611 0.448 5.36 7.0174 0.9968 3039326 ChemDiv3_013568 CCC(N1C(=O)CSc2ccc(cc12)C(C)(C)C)C(=O)NCc3ccc(OC)cc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I17 compound treatment 0.219 0.0634 0.67 0.233 0.0702 0.84 1.0642 0.9934 3039327 ChemDiv3_013569 O=C(CCN1C(=O)COc2ccccc12)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I18 compound treatment 0.228 0.0724 0.76 0.252 0.0892 1.07 1.2918 0.9862 3039329 ChemDiv3_013570 COc1ccccc1CN2CC(CC2=O)C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I19 compound treatment 0.208 0.0524 0.55 0.201 0.0382 0.46 0.7118 0.9957 3039330 ChemDiv3_013571 CCOc1ccccc1CN2C(C(=O)NCCCN3C(C)CCCC3C)c4ccccc4C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I20 compound treatment 0.48 0.324 3.41 0.494 0.331 3.96 5.2106 0.9972 3039332 ChemDiv3_013572 CCc1ccc(CNC(=O)c2ccc(CSCc3ccc(C)cc3)o2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I21 compound treatment 0.114 -0.0416 -0.44 0.118 -0.0448 -0.54 -0.6885 -0.9948 3122692 ChemDiv3_013573 CS(=O)(=O)N1CCC(CC1)C(=O)NCCN2CCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I22 compound treatment 0.281 0.125 1.32 0.342 0.179 2.14 2.4468 0.9726 3039333 ChemDiv3_013574 CC1CCCCC1NC(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I23 mock treatment 0.138 -0.0176 -0.19 0.153 -0.00984 -0.12 -0.2142 -0.9762 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 I24 mock treatment 0.155 -6.25E-4 -0.01 0.154 -0.00884 -0.11 -0.0795 -0.7495 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J01 compound treatment 0.826 0.67 7.04 0.867 0.704 8.42 10.9358 0.996 3122693 ChemDiv3_013575 CC1CCCC(NC(=O)c2ccc(CSCc3cccc(C)c3)o2)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J02 compound treatment 0.215 0.0594 0.62 0.213 0.0502 0.6 0.8653 0.9998 3122694 ChemDiv3_013576 Brc1ccc2[nH]c(=O)cc(C(=O)NCC3CCCO3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J03 compound treatment 0.199 0.0434 0.46 0.21 0.0472 0.56 0.7211 0.9944 3039336 ChemDiv3_013577 Clc1cccc(Sc2cc(C(=O)NCCN3CCCC3)c4ccccc4n2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J04 compound treatment 0.148 -0.00763 -0.08 0.184 0.0212 0.25 0.1224 0.4609 3122695 ChemDiv3_013578 COc1ccc(cc1)N2CCC(CNS(=O)(=O)c3cccc(Cl)c3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J05 compound treatment 0.275 0.119 1.25 0.262 0.0992 1.19 1.7254 0.9996 3122696 ChemDiv3_013579 Cc1ccc(cc1)c2ccc(=O)n(CCC(=O)NCCN3CCN(CC3)c4cccc(Cl)c4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J06 compound treatment 0.649 0.493 5.18 0.624 0.461 5.52 7.5655 0.9995 3039338 ChemDiv3_013580 CC1N=C(c2ccccc2)c3ccccc3N(CCCOc4ccc(F)cc4)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J07 compound treatment 0.198 0.0424 0.45 0.209 0.0462 0.55 0.7052 0.9943 3122697 ChemDiv3_013581 CC(C)NC(=O)C1CCC(=O)N1Cc2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J08 compound treatment 0.215 0.0594 0.62 0.218 0.0552 0.66 0.9076 0.9996 3039340 ChemDiv3_013582 O=C(NC1CCCC1)C2CCCN(C2)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J09 compound treatment 0.169 0.0134 0.14 0.207 0.0442 0.53 0.4729 0.8651 3122698 ChemDiv3_013583 CCS(=O)(=O)N1CCCC(C1)C(=O)NCCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J10 compound treatment 0.265 0.109 1.15 0.352 0.189 2.26 2.4126 0.9506 3122699 ChemDiv3_013584 COC(CNC(=O)c1ccc2Sc3ccccc3C(=O)N(CC=C)c2c1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J11 compound treatment 0.463 0.307 3.23 0.53 0.367 4.39 5.3889 0.9885 3039343 ChemDiv3_013585 CSc1ccccc1Sc2cc(C(=O)NCc3ccco3)c4ccccc4n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J12 compound treatment 0.178 0.0224 0.23 0.172 0.00916 0.11 0.2436 0.9397 3039473 ChemDiv3_013586 COC(=O)c1ccc2SCC(=O)N(CC#N)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J13 compound treatment 0.96 0.804 8.45 1.001 0.838 10.03 13.0646 0.9964 3039389 ChemDiv3_013587 CCc1cccc(NC(=S)N(CCOC)C(C)c2cccs2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J14 compound treatment 0.209 0.0534 0.56 0.223 0.0602 0.72 0.9053 0.9924 3039391 ChemDiv3_013588 COC(CNC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J15 compound treatment 0.094 -0.0616 -0.65 0.102 -0.0608 -0.73 -0.9724 -0.9983 3039392 ChemDiv3_013589 Clc1ccccc1NC(=S)Nc2ccc(CN3CCOCC3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J16 compound treatment 0.442 0.286 3.01 0.408 0.245 2.93 4.2008 0.9999 3039394 ChemDiv3_013590 CC(C)c1ccc(NC(=O)CN2N=C(CCC2=O)c3ccc(Cl)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J17 compound treatment 0.315 0.159 1.67 0.346 0.183 2.19 2.7331 0.9912 3039396 ChemDiv3_013591 CCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J18 compound treatment 0.113 -0.0426 -0.45 0.107 -0.0558 -0.67 -0.789 -0.981 3039397 ChemDiv3_013592 Cc1ccc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J19 compound treatment 0.425 0.269 2.83 0.383 0.22 2.63 3.8631 0.9994 3122700 ChemDiv3_013593 Cc1ccc(CN2C(=O)/C(=C/C(=O)NCCc3ccccc3)/Sc4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J20 compound treatment 0.214 0.0584 0.61 0.211 0.0482 0.58 0.8409 0.9995 3122701 ChemDiv3_013594 CCCCN1CCCc2cc(CN(Cc3ccco3)C(=S)Nc4ccc(Cl)cc4OC)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J21 compound treatment 0.281 0.125 1.32 0.253 0.0902 1.08 1.6938 0.9951 3039400 ChemDiv3_013595 Cc1ccc(cc1)C2=NN(CCC(=O)N3CCC(CC3)C(=O)N)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J22 compound treatment 0.201 0.0454 0.48 0.242 0.0792 0.95 1.0067 0.9495 3039401 ChemDiv3_013596 CCCCN(C1CCN(CC1)C(=O)C)C(=S)Nc2cccc(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J23 mock treatment 0.19 0.0344 0.36 0.233 0.0702 0.84 0.8488 0.929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 J24 mock treatment 0.15 -0.00563 -0.06 0.154 -0.00884 -0.11 -0.1166 -0.9621 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K01 compound treatment 0.575 0.419 4.4 0.576 0.413 4.94 6.6099 0.9983 3122702 ChemDiv3_013597 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K02 compound treatment 0.268 0.112 1.18 0.241 0.0782 0.94 1.4958 0.9934 3122703 ChemDiv3_013598 COc1ccc(Br)cc1CNC(=O)C2CCN(CC2)C(=O)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K03 compound treatment 0.768 0.612 6.43 0.798 0.635 7.6 9.9213 0.9966 3039404 ChemDiv3_013599 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K04 compound treatment 0.148 -0.00763 -0.08 0.104 -0.0588 -0.7 -0.5545 -0.7825 3122704 ChemDiv3_013600 CC(=O)N1CCC(CC1)N(C2CCCC2)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K05 compound treatment 0.5 0.344 3.62 0.553 0.39 4.67 5.8583 0.992 3122705 ChemDiv3_013601 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)N3CCC(=CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K06 compound treatment 0.256 0.1 1.05 0.274 0.111 1.33 1.6858 0.9934 3039406 ChemDiv3_013602 O=C(Cn1nc(ccc1=O)c2ccccc2)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K07 compound treatment 0.248 0.0924 0.97 0.207 0.0442 0.53 1.0596 0.9592 3122706 ChemDiv3_013603 Clc1ccc(CCNC(=O)CCc2cn(Cc3ccccc3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K08 compound treatment 0.343 0.187 1.97 0.33 0.167 2.0 2.8057 1.0 3039407 ChemDiv3_013604 COc1ccc(CNC(=O)CN2N=C(CCC2=O)c3ccc(Cl)cc3)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K09 compound treatment 0.119 -0.0366 -0.38 0.139 -0.0238 -0.29 -0.4737 -0.9892 3122707 ChemDiv3_013605 CC(C)N1CCC(CC1)N(Cc2ccco2)C(=S)Nc3cccc(Cl)c3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K10 compound treatment 0.128 -0.0276 -0.29 0.106 -0.0568 -0.68 -0.6861 -0.9279 3122708 ChemDiv3_013606 CCc1cccc(NC(=S)N(C(C)c2cccs2)C3CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K11 compound treatment 0.139 -0.0166 -0.17 0.126 -0.0368 -0.44 -0.4352 -0.9178 3039409 ChemDiv3_013607 CC1(C)CC(=O)c2cc(OCC(=O)N3CCN(Cc4ccccc4)CC3)ccc2O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K12 compound treatment 0.224 0.0684 0.72 0.254 0.0912 1.09 1.279 0.9794 3122709 ChemDiv3_013608 CC1CC(C)CN(C1)S(=O)(=O)N2CCCC(C2)C(=O)NC3CCCC(C)C3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K13 compound treatment 0.193 0.0374 0.39 0.213 0.0502 0.6 0.7019 0.9788 3039411 ChemDiv3_013609 CC1(C)CC(=O)c2cc(OCC(=O)NC3CCCC3)ccc2O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K14 compound treatment 0.325 0.169 1.78 0.346 0.183 2.19 2.8074 0.9946 3122710 ChemDiv3_013610 CC1CCCC(NC(=O)CCSCc2ccc(C)cc2)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K15 compound treatment 0.085 -0.0706 -0.74 0.096 -0.0668 -0.8 -1.09 -0.9993 3122711 ChemDiv3_013611 Clc1ccc(CCNC(=O)c2ccc3n(cnc3c2)C4CCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K16 compound treatment 0.109 -0.0466 -0.49 0.103 -0.0598 -0.72 -0.8525 -0.9828 3039414 ChemDiv3_013612 CCOC(=O)N1CCC(CC1)N(CCN(C)C)C(=S)Nc2ccc(C)c(F)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K17 compound treatment 0.234 0.0784 0.82 0.258 0.0952 1.14 1.3871 0.9873 3039474 ChemDiv3_013613 CN(Cc1ccccc1)C(=O)CCN2C(=O)COc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K18 compound treatment 0.238 0.0824 0.87 0.218 0.0552 0.66 1.0784 0.9911 3039475 ChemDiv3_013614 CCC1Sc2ccccc2N(CC(=O)NC3CC3)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K19 compound treatment 0.231 0.0754 0.79 0.166 0.00316 0.04 0.5865 0.74 3039476 ChemDiv3_013615 COc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K20 compound treatment 0.695 0.539 5.66 1.301 1.14 13.62 13.6346 0.9245 3039477 ChemDiv3_013616 Cc1ccc(CSCc2ccc(o2)C(=O)NC3CCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K21 compound treatment 0.814 0.658 6.91 0.773 0.61 7.3 10.0514 0.9996 3039479 ChemDiv3_013617 Clc1ccc(SCCNC(=O)Nc2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K22 compound treatment 0.246 0.0904 0.95 0.216 0.0532 0.64 1.1209 0.981 3039481 ChemDiv3_013618 CC1CCCCC1NC(=O)CCn2nc(ccc2=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K23 mock treatment 0.126 -0.0296 -0.31 0.14 -0.0228 -0.27 -0.4133 -0.9979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 K24 mock treatment 0.149 -0.00663 -0.07 0.149 -0.0138 -0.17 -0.1663 -0.9258 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L01 compound treatment 0.222 0.0664 0.7 0.25 0.0872 1.04 1.2303 0.9808 3122712 ChemDiv3_013619 Cc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L02 compound treatment 0.557 0.401 4.22 0.548 0.385 4.61 6.2393 0.999 1108774 ChemDiv3_013620 COC(=O)C(C)C1Sc2ccccc2NC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L03 compound treatment 0.242 0.0864 0.91 0.241 0.0782 0.94 1.3027 0.9999 3122713 ChemDiv3_013621 COc1ccc(CN2CC(CC2=O)C(=O)NCCN3CCN(CC3)c4ccccc4F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L04 compound treatment 0.205 0.0494 0.52 0.198 0.0352 0.42 0.6641 0.9946 3122714 ChemDiv3_013622 CN(Cc1ccccc1)C(=O)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)Nc4ccccc4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L05 compound treatment 0.113 -0.0426 -0.45 0.123 -0.0398 -0.48 -0.6536 -0.9995 3039484 ChemDiv3_013623 CC1CCCC(C)N1CCNC(=O)c2ccc3n(cnc3c2)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L06 compound treatment 0.118 -0.0376 -0.4 0.148 -0.0148 -0.18 -0.405 -0.9348 3122888 ChemDiv3_013624 CC(N(CCN(C)C)C(=S)Nc1cc(F)cc(F)c1)c2ccncc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L07 compound treatment 0.21 0.0544 0.57 0.211 0.0482 0.58 0.8112 1.0 3039485 ChemDiv3_013625 CCCCN1CC(CC1=O)C(=O)NCCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L08 compound treatment 0.38 0.224 2.36 0.458 0.295 3.53 4.1634 0.9807 3122889 ChemDiv3_013626 Cc1ccc(CCNC(=O)c2coc3nc4ccccc4nc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L09 compound treatment 0.179 0.0234 0.25 0.183 0.0202 0.24 0.3441 1.0 3039487 ChemDiv3_013627 CCS(=O)(=O)N1CCCC(C1)C(=O)NC2CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L10 compound treatment 0.263 0.107 1.13 0.27 0.107 1.28 1.704 0.998 3122890 ChemDiv3_013628 Fc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)NC3CCCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L11 compound treatment 0.497 0.341 3.59 0.861 0.698 8.35 8.4417 0.9287 3122891 ChemDiv3_013629 CC(CNC(=O)Nc1ccccc1)CSc2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L12 compound treatment 0.532 0.376 3.95 0.555 0.392 4.69 6.1128 0.9964 3039490 ChemDiv3_013630 CCc1cccc(NC(=S)N(Cc2c[nH]c3ccccc23)C4CCCC4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L13 compound treatment 0.08 -0.0756 -0.79 0.085 -0.0778 -0.93 -1.2202 -0.9969 3122892 ChemDiv3_013631 CC(C)N1CCC(CC1)N(CCN(C)C)C(=S)Nc2cc(C)cc(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L14 compound treatment 0.194 0.0384 0.4 0.214 0.0512 0.61 0.7178 0.9795 3122893 ChemDiv3_013632 O=C(NCc1cccs1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L15 compound treatment 0.375 0.219 2.3 0.393 0.23 2.75 3.5763 0.9961 3039493 ChemDiv3_013633 CC(CNC(=S)Nc1cccc(Cl)c1)CSc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L16 compound treatment 0.702 0.546 5.74 0.7 0.537 6.43 8.6021 0.9984 3122894 ChemDiv3_013634 COc1ccc(NC(=S)N(Cc2cccn2Cc3ccc(C)cc3C)Cc4ccccc4)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L17 compound treatment 0.197 0.0414 0.43 0.182 0.0192 0.23 0.4693 0.9553 3039496 ChemDiv3_013635 COc1ccc(cc1)C2=NN(CC(=O)NCC3CCCO3)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L18 compound treatment 0.108 -0.0476 -0.5 0.096 -0.0668 -0.8 -0.9192 -0.9745 3122895 ChemDiv3_013636 COc1ccc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L19 compound treatment 0.091 -0.0646 -0.68 0.089 -0.0738 -0.88 -1.1047 -0.9915 3122896 ChemDiv3_013637 O=C(NC1CCCCC1)c2ccc3n(cnc3c2)C4CCCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L20 compound treatment 0.272 0.116 1.22 0.283 0.12 1.44 1.8808 0.9967 3039498 ChemDiv3_013638 Fc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L21 compound treatment 0.234 0.0784 0.82 0.222 0.0592 0.71 1.0825 0.9972 3039549 ChemDiv3_013639 Cc1ccc(cc1)C2=NN(CCC(=O)NCC=C)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L22 compound treatment 0.191 0.0354 0.37 0.15 -0.0128 -0.15 0.1541 0.3832 3039550 ChemDiv3_013640 Cc1ccc(Nc2cc(C(=O)NCC3CCCO3)c4ccccc4n2)cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L23 mock treatment 0.155 -6.25E-4 -0.01 0.143 -0.0198 -0.24 -0.1725 -0.7264 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 L24 mock treatment 0.151 -0.00463 -0.05 0.205 0.0422 0.5 0.3223 0.6361 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M01 compound treatment 0.097 -0.0586 -0.62 0.096 -0.0668 -0.8 -1.0009 -0.9917 3039551 ChemDiv3_013641 CCC1CCCCN1CCCNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M02 compound treatment 0.212 0.0564 0.59 0.238 0.0752 0.9 1.0545 0.9794 3039553 ChemDiv3_013642 CC1CCCC(NC(=O)C2CCN(CC2)C(=O)N(C)C)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M03 compound treatment 0.27 0.114 1.2 0.278 0.115 1.38 1.8236 0.9977 3039554 ChemDiv3_013643 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCC=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M04 compound treatment 0.042 -0.114 -1.19 0.044 -0.119 -1.42 -1.8493 -0.9962 3122897 ChemDiv3_013644 CC(C)N(C(C)c1ccccn1)C(=S)Nc2ccc(Oc3ccccc3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M05 compound treatment 0.204 0.0484 0.51 0.195 0.0322 0.38 0.6313 0.9906 3039557 ChemDiv3_013645 Cc1ccc(CCNC(=O)C2CCN(CC2)c3nc4ccccc4o3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M06 compound treatment 0.179 0.0234 0.25 0.242 0.0792 0.95 0.8433 0.8619 3122898 ChemDiv3_013646 CC(NC(=O)Cn1nc(ccc1=O)c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M07 compound treatment 0.282 0.126 1.33 0.354 0.191 2.29 2.5557 0.9665 3039558 ChemDiv3_013647 CCc1ccc(CNC(=O)CCc2cn(Cc3ccccc3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M08 compound treatment 0.099 -0.0566 -0.59 0.099 -0.0638 -0.76 -0.9607 -0.9923 3122899 ChemDiv3_013648 O=C(CCN1C(=O)COc2ccccc12)NCCN3CCc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M09 compound treatment 0.091 -0.0646 -0.68 0.086 -0.0768 -0.92 -1.13 -0.9889 3122900 ChemDiv3_013649 CC(C)CCN(C)C1CCN(CC1)C(=O)Nc2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M10 compound treatment 0.405 0.249 2.62 0.482 0.319 3.82 4.5521 0.9831 3039560 ChemDiv3_013650 Clc1ccc(CSCCC(=O)N2CCN(CC2)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M11 compound treatment 0.185 0.0294 0.31 0.199 0.0362 0.43 0.524 0.9863 3122901 ChemDiv3_013651 CC1CCN(CC1)C(=O)CNC(=O)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M12 compound treatment 0.178 0.0224 0.23 0.157 -0.00584 -0.07 0.1167 0.4761 3039562 ChemDiv3_013652 CCS(=O)(=O)N1CCC(CC1)C(=O)NCCCN2CCN(CC2)c3ccccc3F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M13 compound treatment 0.184 0.0284 0.3 0.168 0.00516 0.06 0.2543 0.8358 3122902 ChemDiv3_013653 CCCCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)cc(C(=O)NCCc3ccc(Cl)cc3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M14 compound treatment 0.522 0.366 3.85 0.517 0.354 4.24 5.7171 0.9988 3122903 ChemDiv3_013654 CC1CCCCC1NC(=O)CCSCc2cccc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M15 compound treatment 0.083 -0.0726 -0.76 0.089 -0.0738 -0.88 -1.1641 -0.9973 3039565 ChemDiv3_013655 CCc1ccc(CNC(=O)c2ccc3n(cnc3c2)C4CCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M16 compound treatment 0.214 0.0584 0.61 0.282 0.119 1.43 1.4416 0.9289 3122904 ChemDiv3_013656 Fc1ccc(cc1Cl)N2CC(CC2=O)C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M17 compound treatment 0.198 0.0424 0.45 0.181 0.0182 0.22 0.4683 0.9456 3122905 ChemDiv3_013657 CC1CCCC(C)N1CCCNC(=O)C2N(CCc3ccc(Cl)cc3)C(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M18 compound treatment 0.178 0.0224 0.23 0.178 0.0152 0.18 0.2944 0.9918 3039568 ChemDiv3_013658 Cc1ccc(CS(=O)(=O)CCC(=O)NC2CC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M19 compound treatment 0.164 0.00837 0.09 0.176 0.0132 0.16 0.1735 0.9622 3039569 ChemDiv3_013659 Cc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M20 compound treatment 0.474 0.318 3.34 0.48 0.317 3.79 5.0476 0.998 3122906 ChemDiv3_013660 CC(C)CCNC(=O)c1ccc(CSCc2ccc(C)cc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M21 compound treatment 0.773 0.617 6.48 0.582 0.419 5.01 8.1311 0.9919 3039572 ChemDiv3_013661 Clc1ccc(SCCNC(=S)Nc2cccc(Cl)c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M22 compound treatment 0.267 0.111 1.17 0.226 0.0632 0.76 1.3614 0.9776 3122907 ChemDiv3_013662 COc1cccc(CNC(=O)CCn2nc(ccc2=O)c3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M23 mock treatment 0.146 -0.00963 -0.1 0.131 -0.0318 -0.38 -0.3409 -0.8648 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 M24 mock treatment 0.143 -0.0126 -0.13 0.158 -0.00484 -0.06 -0.1347 -0.9311 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N01 compound treatment 0.236 0.0804 0.84 0.218 0.0552 0.66 1.0635 0.9926 3122908 ChemDiv3_013663 Cc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N02 compound treatment 0.411 0.255 2.68 0.395 0.232 2.78 3.8606 0.9998 3039574 ChemDiv3_013664 O=C(CN1C(=O)/C(=C/c2ccccc2)/Sc3ccccc13)NC4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N03 compound treatment 0.191 0.0354 0.37 0.228 0.0652 0.78 0.8139 0.9425 3039631 ChemDiv3_013665 CC(C)CCNC(=O)C1CCC(=O)N1CCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N04 compound treatment 0.382 0.226 2.38 0.427 0.264 3.16 3.916 0.9902 3039632 ChemDiv3_013666 Cc1ccccc1NS(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCc5ccccc45)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N05 compound treatment 0.111 -0.0446 -0.47 0.117 -0.0458 -0.55 -0.7193 -0.9969 3039634 ChemDiv3_013667 O=C(c1ccc2n(cnc2c1)C3CCCCC3)n4ccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N06 compound treatment 0.087 -0.0686 -0.72 0.093 -0.0698 -0.84 -1.1005 -0.9973 3039635 ChemDiv3_013668 COc1cccc(NC(=S)N(CCN(C)C)C(C)c2ccncc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N07 compound treatment 0.862 0.706 7.42 0.863 0.7 8.38 11.1693 0.9982 3039637 ChemDiv3_013669 CCOc1ccccc1NC(=S)NCC(C)CSc2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N08 compound treatment 0.502 0.346 3.64 0.477 0.314 3.76 5.2302 0.9999 3039638 ChemDiv3_013670 COC(CNC(=O)c1coc2nc3ccccc3nc12)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N09 compound treatment 0.179 0.0234 0.25 0.205 0.0422 0.5 0.5302 0.9453 3122909 ChemDiv3_013671 CN1CCN(CC1)C(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N10 compound treatment 0.23 0.0744 0.78 0.263 0.1 1.2 1.3997 0.9785 3039640 ChemDiv3_013672 CC1CC(C)CN(C1)C(=O)c2ccc(CNS(=O)(=O)c3ccc(F)cc3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N11 compound treatment 0.181 0.0254 0.27 0.254 0.0912 1.09 0.9596 0.8547 3122910 ChemDiv3_013673 CCCS(=O)(=O)N1CCCC(C1)C(=O)NC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N12 compound treatment 0.174 0.0184 0.19 0.195 0.0322 0.38 0.4085 0.9491 3039642 ChemDiv3_013674 CNC(=O)C1CCC(CNS(=O)(=O)c2ccc(C)cc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N13 compound treatment 0.133 -0.0226 -0.24 0.147 -0.0158 -0.19 -0.3021 -0.9937 3122911 ChemDiv3_013675 CN(Cc1ccccc1)C(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N14 compound treatment 0.162 0.00637 0.07 0.194 0.0312 0.37 0.3109 0.821 3122912 ChemDiv3_013676 O=C(NCc1ccccn1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N15 compound treatment 0.136 -0.0196 -0.21 0.149 -0.0138 -0.17 -0.2629 -0.9941 3039644 ChemDiv3_013677 CCCCN(CC)Cc1ccc(CNC(=O)Nc2ccccc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N16 compound treatment 0.091 -0.0646 -0.68 0.083 -0.0798 -0.96 -1.1554 -0.986 3122913 ChemDiv3_013678 CC1CCCCC1N2CCC(CNC(=S)Nc3cccc(Cl)c3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N17 compound treatment 0.205 0.0494 0.52 0.203 0.0402 0.48 0.7064 0.9993 3039647 ChemDiv3_013679 COc1ccc(cc1)C2=NN(CC(=O)N3CCCC3)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N18 compound treatment 0.337 0.181 1.9 0.326 0.163 1.95 2.7273 0.9999 3122914 ChemDiv3_013680 CC(N(CCCN1CCOCC1)C(=S)Nc2cc(C)cc(C)c2)c3cc4ccccc4o3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N19 compound treatment 0.326 0.17 1.79 0.309 0.146 1.75 2.5018 0.9999 3122915 ChemDiv3_013681 CCc1ccc(NC(=O)N2CCC(C2)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N20 compound treatment 0.155 -6.25E-4 -0.01 0.18 0.0172 0.21 0.1405 0.6841 3039649 ChemDiv3_013682 CCN1CCN(CC1)C(=O)c2ccc(CS(=O)(=O)Cc3ccccc3F)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N21 compound treatment 0.287 0.131 1.38 0.336 0.173 2.07 2.4406 0.9805 3123093 ChemDiv3_013683 CCOc1ccc(NC(=O)NCc2cccn2C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N22 compound treatment 0.165 0.00937 0.1 0.155 -0.00784 -0.09 0.0033 0.024 3123094 ChemDiv3_013684 CC1CC(C)CN(C1)C(=O)c2cc(Nc3ccc(C)c(C)c3)nc4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N23 mock treatment 0.147 -0.00863 -0.09 0.152 -0.0108 -0.13 -0.1558 -0.9846 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 N24 mock treatment 0.149 -0.00663 -0.07 0.135 -0.0278 -0.33 -0.2848 -0.8367 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O01 compound treatment 0.116 -0.0396 -0.42 0.129 -0.0338 -0.4 -0.5806 -0.9999 3039653 ChemDiv3_013685 CN(C)CCNC(=O)c1ccc(Sc2ccc(C)cc2)c(NC(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O02 compound treatment 0.21 0.0544 0.57 0.213 0.0502 0.6 0.8281 0.9997 3123095 ChemDiv3_013686 CC(NC(=O)C1CCN(CC1)C(=O)N(C)C)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O03 compound treatment 0.259 0.103 1.09 0.256 0.0932 1.11 1.5558 0.9999 3039655 ChemDiv3_013687 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O04 compound treatment 0.181 0.0254 0.27 0.181 0.0182 0.22 0.3421 0.9949 3123096 ChemDiv3_013688 CN(C)C(=O)N1CCC(CC1)C(=O)N2CCC3(CC2)OCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O05 compound treatment 0.102 -0.0536 -0.56 0.095 -0.0678 -0.81 -0.9722 -0.9841 3123097 ChemDiv3_013689 CCc1ccc(CNC(=O)C2CCN(CC2)c3nc4ccccc4o3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O06 compound treatment 0.183 0.0274 0.29 0.203 0.0402 0.48 0.543 0.9699 3039711 ChemDiv3_013690 COc1ccc(Br)cc1CNC(=O)C2CCCN(C2)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O07 compound treatment 0.266 0.11 1.16 0.29 0.127 1.52 1.8955 0.991 3039713 ChemDiv3_013691 CC1CCCCC1NC(=O)C2CCCN(C2)c3nc4ccccc4o3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O08 compound treatment 0.23 0.0744 0.78 0.268 0.105 1.26 1.442 0.9737 3039714 ChemDiv3_013692 Cc1ccc(Cl)cc1N2CCN(CC2)C(=O)CCN3C(=O)COc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O09 compound treatment 0.088 -0.0676 -0.71 0.093 -0.0698 -0.84 -1.0931 -0.9967 3039715 ChemDiv3_013693 CC(C)CCN(C)C1CCN(CC1)S(=O)(=O)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O10 compound treatment 0.185 0.0294 0.31 0.18 0.0172 0.21 0.3633 0.9804 3039717 ChemDiv3_013694 CC(C)CCNC(=O)C1CCCN(C1)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O11 compound treatment 0.196 0.0404 0.42 0.203 0.0402 0.48 0.6396 0.9981 3039718 ChemDiv3_013695 OC(=O)c1c2CN(CCc2nc3ccccc13)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O12 compound treatment 0.167 0.0114 0.12 0.189 0.0262 0.31 0.3058 0.9128 3039719 ChemDiv3_013696 CCS(=O)(=O)N1CCC(CC1)C(=O)NCC=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O13 compound treatment 0.139 -0.0166 -0.17 0.147 -0.0158 -0.19 -0.2575 -0.9992 3123098 ChemDiv3_013697 CC(C)N(C1CCN(CC1)C(=O)C)C(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O14 compound treatment 0.771 0.615 6.46 0.771 0.608 7.28 9.7152 0.9983 3039721 ChemDiv3_013698 Cc1ccc(CSCC(=O)NCCc2ccc(Cl)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O15 compound treatment 0.222 0.0664 0.7 0.236 0.0732 0.88 1.1118 0.9936 3123099 ChemDiv3_013699 CCC1Oc2ccccc2N(CC(=O)N3CC(C)CC(C)C3)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O16 compound treatment 0.202 0.0464 0.49 0.217 0.0542 0.65 0.8026 0.9901 3123100 ChemDiv3_013700 O=C(NCCc1ccccc1)C2CCC(=O)N2C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O17 compound treatment 0.155 -6.25E-4 -0.01 0.171 0.00816 0.1 0.0644 0.6581 3039724 ChemDiv3_013701 C=CCNC(=O)CCN1C(=O)COc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O18 compound treatment 0.168 0.0124 0.13 0.196 0.0332 0.4 0.3724 0.8921 3123101 ChemDiv3_013702 Cc1ccc(cc1)c2ccc(=O)n(CC(=O)NC3CCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O19 compound treatment 0.068 -0.0876 -0.92 0.061 -0.102 -1.22 -1.5124 -0.9904 3039726 ChemDiv3_013703 CC(C)CCN(C1CCN(CC1)C(C)C)C(=S)Nc2ccc(cc2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O20 compound treatment 0.673 0.517 5.43 0.615 0.452 5.41 7.6676 1.0 3123102 ChemDiv3_013704 Cc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCc4ccccc4C3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O21 compound treatment 0.225 0.0694 0.73 0.237 0.0742 0.89 1.1426 0.9952 3039728 ChemDiv3_013705 CC(C)N(C(C)c1ccccn1)C(=S)Nc2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O22 compound treatment 0.155 -6.25E-4 -0.01 0.169 0.00616 0.07 0.0474 0.6415 3123103 ChemDiv3_013706 O=C(CCn1nc(ccc1=O)c2ccccc2)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O23 mock treatment 0.147 -0.00863 -0.09 0.14 -0.0228 -0.27 -0.2573 -0.8937 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 O24 mock treatment 0.164 0.00837 0.09 0.156 -0.00684 -0.08 0.0043 0.0358 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P01 compound treatment 0.221 0.0654 0.69 0.241 0.0782 0.94 1.1467 0.9885 3123104 ChemDiv3_013707 O=C(CCN1N=C(CCC1=O)c2ccccc2)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P02 compound treatment 0.6 0.444 4.67 0.66 0.497 5.95 7.5062 0.9928 3039730 ChemDiv3_013708 O=C(CN1C(=O)/C(=C/c2ccccc2)/Sc3ccccc13)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P03 compound treatment 0.167 0.0114 0.12 0.215 0.0522 0.62 0.5257 0.8275 3123105 ChemDiv3_013709 COc1ccc(CCN2CC(CC2=O)C(=O)NCc3ccc(F)cc3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P04 compound treatment 0.245 0.0894 0.94 0.252 0.0892 1.07 1.418 0.998 3123106 ChemDiv3_013710 CCCCN(C)C(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)Nc3cccc(OC)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P05 compound treatment 0.163 0.00737 0.08 0.167 0.00416 0.05 0.0899 0.977 3039732 ChemDiv3_013711 O=C(NCCN1CCCCCC1)c2ccc3n(cnc3c2)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P06 compound treatment 1.013 0.857 9.0 1.022 0.859 10.28 13.6359 0.9978 3123107 ChemDiv3_013712 CC1CCCCC1NC(=O)c2ccc3Sc4ccccc4C(=O)N(CC=C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P07 compound treatment 0.201 0.0454 0.48 0.233 0.0702 0.84 0.9305 0.964 3039734 ChemDiv3_013713 Fc1ccc(cc1Cl)N2CC(CC2=O)C(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P08 compound treatment 0.26 0.104 1.1 0.285 0.122 1.46 1.8086 0.99 3123108 ChemDiv3_013714 CC1CCCN(CCCNC(=O)c2coc3nc4ccccc4nc23)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P09 compound treatment 0.173 0.0174 0.18 0.18 0.0172 0.21 0.2742 0.9983 3039736 ChemDiv3_013715 CCS(=O)(=O)N1CCCC(C1)C(=O)N2CCC3(CC2)OCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P10 compound treatment 0.238 0.0824 0.87 0.252 0.0892 1.07 1.366 0.9946 3123109 ChemDiv3_013716 CCCN(CCC)C(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P11 compound treatment 0.202 0.0464 0.49 0.295 0.132 1.58 1.4625 0.8839 3039794 ChemDiv3_013717 CCCS(=O)(=O)N1CCCC(C1)C(=O)N2CCN(CC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P12 compound treatment 0.164 0.00837 0.09 0.204 0.0412 0.49 0.4104 0.8204 3039795 ChemDiv3_013718 Clc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NCC3CCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P13 compound treatment 0.287 0.131 1.38 0.275 0.112 1.34 1.9245 0.9999 3039797 ChemDiv3_013719 COc1ccc(NC(=O)NCC(C)CSc2ccc(Cl)cc2)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P14 compound treatment 0.177 0.0214 0.22 0.227 0.0642 0.77 0.7015 0.8772 3039798 ChemDiv3_013720 O=C(NC1CCCCC1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P15 compound treatment 0.185 0.0294 0.31 0.212 0.0492 0.59 0.634 0.9547 3039800 ChemDiv3_013721 CCOc1ccc(NC(=O)N(CCC(C)C)C(C)c2cccs2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P16 compound treatment 0.122 -0.0336 -0.35 0.132 -0.0308 -0.37 -0.5107 -0.9998 3039801 ChemDiv3_013722 Fc1cc(F)cc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P17 compound treatment 0.196 0.0404 0.42 0.187 0.0242 0.29 0.5042 0.9825 3123110 ChemDiv3_013723 COc1ccc(cc1)C2=NN(CC(=O)NCc3ccc4OCOc4c3)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P18 compound treatment 0.201 0.0454 0.48 0.208 0.0452 0.54 0.719 0.998 3039803 ChemDiv3_013724 CCN1CCCc2cc(CN(CCN3CCOCC3)C(=S)Nc4c(C)cc(C)cc4C)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P19 compound treatment 0.48 0.324 3.41 0.43 0.267 3.2 4.6692 0.9995 3123111 ChemDiv3_013725 Cc1c(Cl)cccc1NC(=S)NCc2cccn2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P20 compound treatment 0.161 0.00537 0.06 0.178 0.0152 0.18 0.1681 0.8853 3123112 ChemDiv3_013726 CC(C)CCNC(=O)c1ccc(cc1)N2CCCC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P21 compound treatment 0.173 0.0174 0.18 0.163 1.56E-4 0.0 0.1304 0.7143 3039807 ChemDiv3_013727 COCCN(C(C)c1cccnc1)C(=S)Nc2c(C)cccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P22 compound treatment 0.158 0.00237 0.02 0.171 0.00816 0.1 0.0866 0.8602 3123113 ChemDiv3_013728 Cc1ccc(Nc2cc(C(=O)N3CCCC3)c4ccccc4n2)cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P23 mock treatment 0.163 0.00737 0.08 0.159 -0.00384 -0.05 0.0223 0.247 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2039 P24 mock treatment 0.14 -0.0156 -0.16 0.16 -0.00284 -0.03 -0.1401 -0.8359 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A01 compound treatment 0.179 -0.0332 -0.35 0.167 -0.0139 -0.17 -0.3639 -0.9429 3123114 ChemDiv3_013729 CC(C)CCNC(=O)c1cc(Nc2ccc(C)c(C)c2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A02 compound treatment 0.125 -0.0872 -0.92 0.115 -0.0659 -0.79 -1.2048 -0.9972 3039810 ChemDiv3_013730 CC(C)N(CCc1ccncc1)C(=S)NCC2CCCO2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A03 compound treatment 0.35 0.138 1.45 0.318 0.137 1.64 2.1835 0.9981 3123115 ChemDiv3_013731 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(/C=C/4\Oc5ccccc5NC4=O)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A04 compound treatment 0.264 0.0518 0.54 0.247 0.0661 0.79 0.9442 0.9834 3039812 ChemDiv3_013732 CCCNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A05 compound treatment 0.281 0.0688 0.72 0.238 0.0571 0.68 0.9943 0.9996 3123116 ChemDiv3_013733 CCCN1CCCc2cc(CN(CCOC)C(=S)Nc3ccccc3OC)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A06 compound treatment 0.844 0.632 6.64 0.733 0.552 6.61 9.3632 1.0 3123117 ChemDiv3_013734 Fc1ccc(CN2C(=O)/C(=C/c3ccccc3)/Sc4ccc(cc24)C(=O)NCC5CCCO5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A07 compound treatment 0.285 0.0728 0.77 0.272 0.0911 1.09 1.3116 0.985 3039815 ChemDiv3_013735 O=C(CCN1N=C(CCC1=O)c2ccccc2)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A08 compound treatment 0.262 0.0498 0.52 0.247 0.0661 0.79 0.9293 0.9799 3123118 ChemDiv3_013736 CCN1CCN(CC1)C(=O)c2ccc(/C=C\3/Sc4ccccc4N(Cc5ccccc5C)C3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A09 compound treatment 0.217 0.00484 0.05 0.173 -0.00791 -0.09 -0.0309 -0.2878 3039817 ChemDiv3_013737 COc1ccc(Nc2cc(C(=O)NCCCN3CCCC3)c4ccccc4n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A10 compound treatment 0.301 0.0888 0.93 0.27 0.0891 1.07 1.4135 0.9978 3039869 ChemDiv3_013738 CCCNC(=O)c1ccc2S/C(=C\c3ccccc3)/C(=O)Nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A11 compound treatment 0.291 0.0788 0.83 0.297 0.116 1.39 1.5677 0.9695 3039870 ChemDiv3_013739 Cc1cccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCCC3=CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A12 compound treatment 0.567 0.355 3.73 0.503 0.322 3.85 5.3602 0.9999 3039872 ChemDiv3_013740 CCOC(=O)N1CCc2c(C(=O)Nc3ccc(OC)cc3OC)c(NCc4cccnc4)sc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A13 compound treatment 0.182 -0.0302 -0.32 0.16 -0.0209 -0.25 -0.4008 -0.9932 3039873 ChemDiv3_013741 O=C(NC1CC1)c2ccc(CS(=O)c3ccccc3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A14 compound treatment 0.176 -0.0362 -0.38 0.156 -0.0249 -0.3 -0.4792 -0.9928 3039875 ChemDiv3_013742 Fc1ccc(CNC(=O)CC2CC3CCC2C3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A15 compound treatment 0.759 0.547 5.74 0.661 0.48 5.74 8.1228 1.0 3039876 ChemDiv3_013743 Fc1cccc(CSCc2ccc(o2)C(=O)NC3CC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A16 compound treatment 0.379 0.167 1.75 0.311 0.13 1.56 2.3397 0.9983 3123119 ChemDiv3_013744 FC(F)(F)c1ccccc1CNC(=O)c2ccc3ccccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A17 compound treatment 0.224 0.0118 0.12 0.167 -0.0139 -0.17 -0.0297 -0.1429 3039878 ChemDiv3_013745 CN(CCN1CCOCC1)C2CCN(CC2)C(=S)Nc3ccc(C)c(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A18 compound treatment 0.347 0.135 1.42 0.331 0.15 1.8 2.2712 0.9931 3123120 ChemDiv3_013746 CSc1ncccc1C(=O)Nc2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A19 compound treatment 0.368 0.156 1.64 0.306 0.125 1.5 2.2157 0.999 3123301 ChemDiv3_013747 O=C(CN1CCOc2ccccc12)NCc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A20 compound treatment 0.293 0.0808 0.85 0.262 0.0811 0.97 1.2865 0.9978 3039880 ChemDiv3_013748 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=O)Cc3cccc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A21 compound treatment 0.101 -0.111 -1.17 0.093 -0.0879 -1.05 -1.5692 -0.9986 3123302 ChemDiv3_013749 CSc1cccc(NC(=S)N(CCc2ccncc2)C(C)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A22 compound treatment 0.3 0.0878 0.92 0.259 0.0781 0.93 1.3131 1.0 3039882 ChemDiv3_013750 Cc1ccc(cc1)C(=O)CCC(=O)NC2=NCCS2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A23 mock treatment 0.226 0.0138 0.15 0.193 0.0121 0.14 0.2051 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 A24 mock treatment 0.244 0.0318 0.33 0.198 0.0171 0.2 0.3811 0.9722 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B01 compound treatment 0.297 0.0848 0.89 0.274 0.0931 1.11 1.4177 0.9939 3123303 ChemDiv3_013751 O=C(CCCC(=O)c1ccccc1)Nc2nc[nH]n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B02 compound treatment 0.635 0.423 4.44 0.525 0.344 4.12 6.0513 0.9993 3123304 ChemDiv3_013752 COC(=O)C1=CN(C=C(C1c2ccc(cc2)C(C)C)C(=O)OC)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B03 compound treatment 0.37 0.158 1.66 0.339 0.158 1.89 2.5097 0.9978 3039884 ChemDiv3_013753 O=C(CCC(=O)c1ccccc1)Nc2ccc(cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B04 compound treatment 0.434 0.222 2.33 0.428 0.247 2.96 3.738 0.9931 1152542 ChemDiv3_013754 CCOC(=O)c1sc2ncnc(Nc3ccc(OCC)cc3)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B05 compound treatment 0.34 0.128 1.34 0.262 0.0811 0.97 1.6355 0.9873 3039887 ChemDiv3_013755 COc1ccc(cc1)C(=O)CCC(=O)NC2=NCCS2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B06 compound treatment 0.511 0.299 3.14 0.403 0.222 2.66 4.0983 0.9966 1277091 ChemDiv3_013756 CC(C)N(C(C)C)C(=O)Cc1c(O)c2ccccc2[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B07 compound treatment 0.659 0.447 4.69 0.597 0.416 4.98 6.8387 0.9996 3039889 ChemDiv3_013757 Cc1ccc(C)c(NC(=O)c2cccs2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B08 compound treatment 0.294 0.0818 0.86 0.262 0.0811 0.97 1.2939 0.9982 3123305 ChemDiv3_013758 CCCCn1c(=O)c(c(O)c2ccccc12)[n+]3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B09 compound treatment 0.826 0.614 6.45 0.775 0.594 7.11 9.5848 0.9988 1250014 ChemDiv3_013759 CCOC(=O)c1c(C)n(CCc2c[nH]c3ccccc23)c(C)c1C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B10 compound treatment 0.314 0.102 1.07 0.22 0.0391 0.47 1.0871 0.9312 1390876 ChemDiv3_013760 CCOc1ccc(CCNC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B11 compound treatment 0.518 0.306 3.21 0.492 0.311 3.72 4.9032 0.9973 3123306 ChemDiv3_013761 CN1/C(=C\C(=O)c2cccc(Cl)c2)/C(C)(C)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B12 compound treatment 1.337 1.12 11.81 1.361 1.18 14.12 18.3374 0.9961 1369757 ChemDiv3_013762 COc1nc(NCC=C)nc(Nc2ccc(Cl)cc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B13 compound treatment 0.174 -0.0382 -0.4 0.144 -0.0369 -0.44 -0.5956 -0.9988 3039948 ChemDiv3_013763 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B14 compound treatment 0.263 0.0508 0.53 0.203 0.0221 0.26 0.5645 0.9474 1530019 ChemDiv3_013764 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N2CCN(CC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B15 compound treatment 0.339 0.127 1.33 0.29 0.109 1.31 1.865 0.9999 1572652 ChemDiv3_013765 CC(C)CCNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B16 compound treatment 0.11 -0.102 -1.07 0.104 -0.0769 -0.92 -1.4093 -0.9971 1260656 ChemDiv3_013766 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B17 compound treatment 0.3 0.0878 0.92 0.214 0.0331 0.4 0.9323 0.9287 3039950 ChemDiv3_013767 CCN(CC)S(=O)(=O)c1ccc2[nH]cc(C(=O)N3CCC(C)CC3)c(=O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B18 compound treatment 1.335 1.12 11.79 1.366 1.19 14.18 18.3649 0.9958 1376292 ChemDiv3_013768 CN(c1ccccc1)c2ncnc3sc(C(=O)Nc4ccc(F)cc4F)c(C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B19 compound treatment 0.317 0.105 1.1 0.238 0.0571 0.68 1.2616 0.9736 3123307 ChemDiv3_013769 CCOC(=O)C1=C(Nc2ncnn2C1c3ccc(F)cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B20 compound treatment 0.253 0.0408 0.43 0.177 -0.00391 -0.05 0.2703 0.6264 3039952 ChemDiv3_013770 O=C(Cn1c(=O)oc2ccccc12)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B21 compound treatment 0.265 0.0528 0.55 0.223 0.0421 0.5 0.7486 0.9988 3123308 ChemDiv3_013771 COc1ccc(cc1O)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B22 compound treatment 0.353 0.141 1.48 0.28 0.0991 1.19 1.8843 0.994 3039954 ChemDiv3_013772 Cc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B23 mock treatment 0.241 0.0288 0.3 0.183 0.00209 0.03 0.2319 0.763 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 B24 mock treatment 0.216 0.00384 0.04 0.167 -0.0139 -0.17 -0.0891 -0.5204 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C01 compound treatment 0.329 0.117 1.23 0.325 0.144 1.72 2.0868 0.9861 3123309 ChemDiv3_013773 Fc1cccc(CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)N5CCCCC5)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C02 compound treatment 0.709 0.497 5.22 0.685 0.504 6.03 7.9545 0.9974 3123310 ChemDiv3_013774 Cc1ccc(cc1)C2CCN(C2)C(=S)NCC3CCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C03 compound treatment 0.52 0.308 3.23 0.484 0.303 3.63 4.8504 0.9984 3039956 ChemDiv3_013775 CCOC(=O)C1CCCN(C1)C(=O)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C04 compound treatment 0.278 0.0658 0.69 0.193 0.0121 0.14 0.5913 0.8369 3123311 ChemDiv3_013776 CN1C(=O)CS(=O)c2ccc(cc12)C(=O)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C05 compound treatment 0.486 0.274 2.88 0.394 0.213 2.55 3.8365 0.9982 3123312 ChemDiv3_013777 CCN1CCCc2cc(CN(C3CCCC3)C(=S)Nc4ccc(OC)cc4)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C06 compound treatment 0.469 0.257 2.7 0.368 0.187 2.24 3.4903 0.9957 3123313 ChemDiv3_013778 COc1ccc(/C=C\2/Sc3ccc(cc3NC2=O)C(=O)NC4CCCc5ccccc45)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C07 compound treatment 0.071 -0.141 -1.48 0.057 -0.124 -1.48 -2.0966 -1.0 3039959 ChemDiv3_013779 CC(C)N(CCCn1cccc1)C(=S)Nc2cccc(c2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C08 compound treatment 0.115 -0.0972 -1.02 0.113 -0.0679 -0.81 -1.296 -0.9936 3039961 ChemDiv3_013780 COc1ccccc1c2c(C)nn3c(cc(C)nc23)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C09 compound treatment 0.451 0.239 2.51 0.315 0.134 1.6 2.9082 0.9767 3123314 ChemDiv3_013781 O=C(CCN1N=C(CCC1=O)c2ccccc2)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C10 compound treatment 0.242 0.0298 0.31 0.225 0.0441 0.53 0.5947 0.9691 3123315 ChemDiv3_013782 COc1ccc(cc1OC)C2OC(=O)CC2C(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C11 compound treatment 0.225 0.0128 0.13 0.146 -0.0349 -0.42 -0.1999 -0.4555 3039963 ChemDiv3_013783 Cc1cccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCCCN3CCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C12 compound treatment 0.367 0.155 1.63 0.262 0.0811 0.97 1.836 0.9695 1503664 ChemDiv3_013784 COc1cccc2C3CC(=NN3C4(CCCCC4)Oc12)c5ccco5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C13 compound treatment 0.31 0.0978 1.03 0.223 0.0421 0.5 1.0828 0.9461 3123316 ChemDiv3_013785 Cc1cc(N2CCN(CC2)c3ccccc3)n4nc(cc4n1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C14 compound treatment 0.517 0.305 3.2 0.324 0.143 1.71 3.4745 0.957 3039966 ChemDiv3_013786 CCOc1ccc(NC(=O)CC2CC3CCC2C3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C15 compound treatment 0.311 0.0988 1.04 0.282 0.101 1.21 1.5893 0.9971 3123317 ChemDiv3_013787 COC(CN(C)c1cc(C)nc2c(c(C)nn12)c3ccc(Cl)cc3)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C16 compound treatment 0.237 0.0248 0.26 0.194 0.0131 0.16 0.2953 0.9702 1340676 ChemDiv3_013788 Cc1cccc(NC(=O)c2ccc3ccccc3c2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C17 compound treatment 0.237 0.0248 0.26 0.201 0.0201 0.24 0.3545 0.9992 3038835 ChemDiv3_013789 COc1ccc(cc1)C2=NN(CCC(=O)NCCN3CCN(CC3)c4cccc(Cl)c4)C(=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C18 compound treatment 0.193 -0.0192 -0.2 0.154 -0.0269 -0.32 -0.3699 -0.9744 3038751 ChemDiv3_013790 CSc1ncccc1C(=O)Nc2ccccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C19 compound treatment 0.353 0.141 1.48 0.312 0.131 1.57 2.155 0.9996 3038753 ChemDiv3_013791 CC(C)CCNC(=O)CN1CCOc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C20 compound treatment 0.351 0.139 1.46 0.308 0.127 1.52 2.1064 0.9998 3038754 ChemDiv3_013792 Clc1cc(NC(=O)Cc2cccc3ccccc23)ccc1N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C21 compound treatment 0.25 0.0378 0.4 0.208 0.0271 0.32 0.5103 0.9949 3038756 ChemDiv3_013793 CCc1ccccc1NC(=S)N(CCc2ccncc2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C22 compound treatment 0.357 0.145 1.52 0.298 0.117 1.4 2.0663 0.9992 3038757 ChemDiv3_013794 Cc1nnc(NC(=O)CCC(=O)c2ccc(C)cc2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C23 mock treatment 0.2 -0.0122 -0.13 0.187 0.00609 0.07 -0.0387 -0.2634 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 C24 mock treatment 0.271 0.0588 0.62 0.209 0.0281 0.34 0.6747 0.959 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D01 compound treatment 0.353 0.141 1.48 0.346 0.165 1.98 2.4427 0.9898 3038759 ChemDiv3_013795 Cc1ccc(NC(=O)CCCC(=O)c2ccccc2)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D02 compound treatment 0.431 0.219 2.3 0.331 0.15 1.8 2.8951 0.9925 3038761 ChemDiv3_013796 CCOC(=O)C1=CN(C)C=C(C1c2cccc(OCc3ccccc3)c2)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D03 compound treatment 0.309 0.0968 1.02 0.291 0.11 1.32 1.6506 0.9918 3123318 ChemDiv3_013797 Brc1ccc(o1)C(=O)Nc2ccc(cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D04 compound treatment 0.506 0.294 3.09 0.443 0.262 3.14 4.3996 1.0 1126343 ChemDiv3_013798 CCOC(CNc1nc(C)nc2sc3CCCCc3c12)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D05 compound treatment 0.39 0.178 1.87 0.292 0.111 1.33 2.2606 0.9861 3123319 ChemDiv3_013799 COc1ccc(NC(=O)CCC(=O)c2ccc(OC)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D06 compound treatment 0.338 0.126 1.32 0.308 0.127 1.52 2.0098 0.9976 1647698 ChemDiv3_013800 CCOC(=O)Cc1c(O)c2ccccc2[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D07 compound treatment 0.582 0.37 3.88 0.473 0.292 3.49 5.2178 0.9986 3123320 ChemDiv3_013801 COc1ccc(CNC(=O)c2cccs2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D08 compound treatment 0.31 0.0978 1.03 0.269 0.0881 1.05 1.4719 0.9999 3123321 ChemDiv3_013802 CC(C)Cn1c(=O)c(c(O)c2ccccc12)[n+]3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D09 compound treatment 0.35 0.138 1.45 0.306 0.125 1.5 2.082 0.9999 3038765 ChemDiv3_013803 CCOC(=O)C1=C(C)NN=C(C)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D10 compound treatment 0.28 0.0678 0.71 0.21 0.0291 0.35 0.75 0.9457 1661248 ChemDiv3_013804 O=C(CCn1c(=S)oc2ccccc12)NN3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D11 compound treatment 0.087 -0.125 -1.31 0.077 -0.104 -1.24 -1.8085 -0.9996 3123322 ChemDiv3_013805 CS(=O)(=O)N1CCC(CC1)c2noc(n2)c3ccc(cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D12 compound treatment 0.343 0.131 1.37 0.268 0.0871 1.04 1.7085 0.9907 1237741 ChemDiv3_013806 COc1nc(NCCO)nc(Nc2ccc(I)cc2C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D13 compound treatment 0.322 0.11 1.15 0.249 0.0681 0.81 1.3918 0.9855 1602373 ChemDiv3_013807 COc1ccc(Cl)cc1NC(=O)c2sc3nc(C)n(C)c(=O)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D14 compound treatment 0.371 0.159 1.67 0.294 0.113 1.35 2.1364 0.9946 3123323 ChemDiv3_013808 OC1(CCN(CC1)S(=O)(=O)c2cccc3nsnc23)c4cccc(c4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D15 compound treatment 0.424 0.212 2.22 0.398 0.217 2.6 3.4099 0.997 1246763 ChemDiv3_013809 CCN(c1cccc(C)c1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCCc4ccccc4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D16 compound treatment 0.083 -0.129 -1.36 0.081 -0.0999 -1.2 -1.8044 -0.998 1438389 ChemDiv3_013810 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)N4CCC5(CC4)OCCO5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D17 compound treatment 0.848 0.636 6.68 0.749 0.568 6.8 9.5283 1.0 3120269 ChemDiv3_013811 COc1cccc(c1)C2C=C(Nc3ncnn23)c4cccc(OC)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D18 compound treatment 0.357 0.145 1.52 0.287 0.106 1.27 1.9733 0.996 1315940 ChemDiv3_013812 Cc1n[nH]c2nc(SCC(=O)NCC3CCCO3)n(c4ccc(C)c(Cl)c4)c(=N)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D19 compound treatment 0.288 0.0758 0.8 0.205 0.0241 0.29 0.7671 0.9055 1259774 ChemDiv3_013813 CCOC(=O)C1=C(C)Nc2ncnn2C1c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D20 compound treatment 0.227 0.0148 0.16 0.159 -0.0219 -0.26 -0.0751 -0.2462 3038770 ChemDiv3_013814 O=C(Cn1c(=O)oc2ccccc12)NCc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D21 compound treatment 0.301 0.0888 0.93 0.22 0.0391 0.47 0.9905 0.949 1440355 ChemDiv3_013815 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(O)cc3)C(=O)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D22 compound treatment 0.341 0.129 1.35 0.268 0.0871 1.04 1.6937 0.9917 3038837 ChemDiv3_013816 Cc1ccc(cc1)S(=O)(=O)CCC(=O)Nc2ccc(C)c(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D23 mock treatment 0.256 0.0438 0.46 0.177 -0.00391 -0.05 0.2926 0.6321 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 D24 mock treatment 0.192 -0.0202 -0.21 0.159 -0.0219 -0.26 -0.335 -0.9944 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E01 compound treatment 0.412 0.2 2.1 0.339 0.158 1.89 2.8216 0.9987 3038838 ChemDiv3_013817 CN(Cc1ccco1)C(=O)c2ccc3Sc4ccccc4C(=O)N(Cc5cccc(F)c5)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E02 compound treatment 0.11 -0.102 -1.07 0.113 -0.0679 -0.81 -1.3332 -0.9906 3038839 ChemDiv3_013818 CC(N1CCC(CNC(=O)Nc2ccc(Cl)cc2)C1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E03 compound treatment 0.123 -0.0892 -0.94 0.111 -0.0699 -0.84 -1.2535 -0.9984 3120270 ChemDiv3_013819 CC1CCN(CCCNC(=O)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E04 compound treatment 0.225 0.0128 0.13 0.186 0.00509 0.06 0.1385 0.9355 3038842 ChemDiv3_013820 CC(CCc1ccccc1)NC(=O)c2cc3c(C)nccc3[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E05 compound treatment 0.329 0.117 1.23 0.253 0.0721 0.86 1.4777 0.9851 3120271 ChemDiv3_013821 Cc1cccc(N2CCN(CC2)C(=O)CN3C(=O)/C(=C\c4cccc(F)c4)/Oc5ccccc35)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E06 compound treatment 0.506 0.294 3.09 0.382 0.201 2.41 3.8835 0.9924 3038844 ChemDiv3_013822 Cc1ccccc1CN2C(=O)/C(=C\c3ccc(cc3)C(=O)N4CCOCC4)/Sc5ccccc25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E07 compound treatment 0.208 -0.00416 -0.04 0.221 0.0401 0.48 0.3083 0.6401 3120272 ChemDiv3_013823 CC1CC(C)CN(C1)C(=O)c2cc(Nc3cccc(c3)C(F)(F)F)nc4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E08 compound treatment 0.43 0.218 2.29 0.355 0.174 2.08 3.0907 0.9989 3120273 ChemDiv3_013824 Clc1ccccc1c2cc(=O)n(CC(=O)NCc3cccs3)c4CCCc42 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E09 compound treatment 0.411 0.199 2.09 0.363 0.182 2.18 3.0173 0.9998 3038846 ChemDiv3_013825 Cn1cc(CN(Cc2ccccc2)C(=O)Nc3ccccc3)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E10 compound treatment 0.4 0.188 1.97 0.345 0.164 1.96 2.7833 1.0 3120274 ChemDiv3_013826 Cc1oc(nc1CS(=O)CC(=O)Nc2ccc(C)cc2)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E11 compound treatment 0.342 0.13 1.36 0.275 0.0941 1.13 1.7603 0.9955 3038848 ChemDiv3_013827 O=C(CCN1N=C(CCC1=O)c2ccccc2)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E12 compound treatment 0.079 -0.133 -1.4 0.076 -0.105 -1.26 -1.8764 -0.9985 1567917 ChemDiv3_013828 COc1ccc(cc1)C2=NN3C(C2)c4cccc(OC)c4OC3(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E13 compound treatment 0.404 0.192 2.01 0.371 0.19 2.27 3.0329 0.9982 3120275 ChemDiv3_013829 CCN(CC)C(=O)c1ccc2S/C(=C\c3ccccc3)/C(=O)Nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E14 compound treatment 0.241 0.0288 0.3 0.213 0.0321 0.38 0.4857 0.9931 3038850 ChemDiv3_013830 Ic1ccccc1NC(=O)CC2CC3CCC2C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E15 compound treatment 0.251 0.0388 0.41 0.216 0.0351 0.42 0.5854 0.9999 3120276 ChemDiv3_013831 Cc1ccc(cc1N2CCCC2=O)C(=O)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E16 compound treatment 0.122 -0.0902 -0.95 0.09 -0.0909 -1.09 -1.4386 -0.9976 3038853 ChemDiv3_013832 CC(CCc1ccccc1)NC(=O)c2ccc3ccccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E17 compound treatment 0.33 0.118 1.24 0.278 0.0971 1.16 1.6966 0.9995 3120277 ChemDiv3_013833 CCCN(CCC)C(=O)c1ccc2S(=O)c3ccccc3C(=O)N(Cc4ccccc4C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E18 compound treatment 0.572 0.36 3.78 0.449 0.268 3.21 4.9405 0.9967 3038854 ChemDiv3_013834 CSc1ncccc1C(=O)NCc2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E19 compound treatment 0.483 0.271 2.84 0.342 0.161 1.93 3.3743 0.982 3120278 ChemDiv3_013835 CC1CCCC(NC(=O)c2cc(C)nn2c3ccccc3)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E20 compound treatment 0.34 0.128 1.34 0.302 0.121 1.45 1.9739 0.9993 3038856 ChemDiv3_013836 Fc1ccc(CNC(=O)Cc2cccc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E21 compound treatment 0.241 0.0288 0.3 0.201 0.0201 0.24 0.3842 0.9934 3120279 ChemDiv3_013837 OC(=O)CNC(=O)/C=C/c1ccccc1F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E22 compound treatment 0.351 0.139 1.46 0.298 0.117 1.4 2.0218 0.9998 3120280 ChemDiv3_013838 Cc1ccc(cc1)C(=O)CCC(=O)Nc2ccc(Br)c(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E23 mock treatment 0.202 -0.0102 -0.11 0.17 -0.0109 -0.13 -0.1677 -0.995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 E24 mock treatment 0.237 0.0248 0.26 0.179 -0.00191 -0.02 0.1684 0.6428 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F01 compound treatment 0.376 0.164 1.72 0.352 0.171 2.05 2.6643 0.9963 3038914 ChemDiv3_013839 Brc1ccc2nc(NC(=O)CCCC(=O)c3ccccc3)sc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F02 compound treatment 0.391 0.179 1.88 0.339 0.158 1.89 2.6657 1.0 1660423 ChemDiv3_013840 CCNC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F03 compound treatment 0.173 -0.0392 -0.41 0.154 -0.0269 -0.32 -0.5184 -0.9927 3038916 ChemDiv3_013841 O=C(NC(c1ccccc1)c2ccccc2)/C=C/c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F04 compound treatment 0.924 0.712 7.48 0.69 0.509 6.09 9.5935 0.9948 1410790 ChemDiv3_013842 CC1CC(C)CN(C1)c2ncnc3scc(c4ccccc4)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F05 compound treatment 0.124 -0.0882 -0.93 0.103 -0.0779 -0.93 -1.3138 -1.0 3038918 ChemDiv3_013843 O=C(CN1C(=O)c2ccccc2C1=O)NC3=NCCS3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F06 compound treatment 0.406 0.194 2.04 0.37 0.189 2.26 3.0393 0.9986 1203378 ChemDiv3_013844 CCCn1c(=O)c(C(=O)NCCc2ccccc2)c(O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F07 compound treatment 0.474 0.262 2.75 0.412 0.231 2.76 3.8997 1.0 1167902 ChemDiv3_013845 CCOC(=O)c1sc2nc(Cc3ccccc3)nc(NCCC4=CCCCC4)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F08 compound treatment 0.373 0.161 1.69 0.323 0.142 1.7 2.3966 1.0 1247758 ChemDiv3_013846 Clc1ccccc1CSc2ncccc2C(=O)NCCC3=CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F09 compound treatment 0.04 -0.172 -1.81 0.04 -0.141 -1.69 -2.4706 -0.9994 3038921 ChemDiv3_013847 CCCC(=O)c1c(O)c2ccccc2oc1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F10 compound treatment 0.378 0.166 1.74 0.286 0.105 1.26 2.1207 0.9872 3120281 ChemDiv3_013848 Cc1c(sc2nc(C)nc(N3CCCCC3)c12)C(=O)Nc4cccc(c4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F11 compound treatment 0.407 0.195 2.05 0.339 0.158 1.89 2.7845 0.9992 3038923 ChemDiv3_013849 Cc1ccc(cc1)c2nc(no2)C3CCN(CC3)S(=O)(=O)c4ccc(cc4)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F12 compound treatment 0.69 0.478 5.02 0.717 0.536 6.41 8.0841 0.9926 1271470 ChemDiv3_013850 CCOc1nc(NC2CCCCC2)nc(Nc3ccc(I)cc3C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F13 compound treatment 0.298 0.0858 0.9 0.286 0.105 1.26 1.5266 0.9867 1253344 ChemDiv3_013851 CC(C)CCNC(=O)c1sc2ncnc(N3CCOCC3)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F14 compound treatment 0.497 0.285 2.99 0.409 0.228 2.73 4.0451 0.9989 1131974 ChemDiv3_013852 O=S(=O)(N1CCCCC1)c2cccc3nsnc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F15 compound treatment 0.426 0.214 2.25 0.374 0.193 2.31 3.2217 0.9999 1344022 ChemDiv3_013853 CC(C)CCNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F16 compound treatment 0.281 0.0688 0.72 0.225 0.0441 0.53 0.8843 0.988 1414503 ChemDiv3_013854 COC(CNC(=O)c1ccc2n(cnc2c1)c3ccc(F)cc3F)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F17 compound treatment 0.705 0.493 5.18 0.711 0.53 6.34 8.1448 0.9949 3120282 ChemDiv3_013855 CCc1ccc(cc1)C2=CC(c3ccc(SC)cc3)n4nnnc4N2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F18 compound treatment 0.396 0.184 1.93 0.45 0.269 3.22 3.6419 0.9701 1418586 ChemDiv3_013856 COc1ccccc1NC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2c4ccc(C)c(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F19 compound treatment 0.555 0.343 3.6 0.478 0.297 3.55 5.0596 1.0 3039096 ChemDiv3_013857 Fc1ccccc1/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccccc5F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F20 compound treatment 0.286 0.0738 0.78 0.21 0.0291 0.35 0.7945 0.9347 3039097 ChemDiv3_013858 Cc1cc2c(=O)n(CC(=O)Nc3ccc(F)cc3F)cnc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F21 compound treatment 0.284 0.0718 0.75 0.22 0.0391 0.47 0.8643 0.9736 3039098 ChemDiv3_013859 COC(=O)C1=CN(C)C=C(C1c2ccc(cc2)C(C)C)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F22 compound treatment 0.32 0.108 1.13 0.247 0.0661 0.79 1.3601 0.9846 3039099 ChemDiv3_013860 O=C(Nc1ccc2OCOc2c1)C3CCC(CNC(=O)c4ccc(=O)[nH]c4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F23 mock treatment 0.263 0.0508 0.53 0.251 0.0701 0.84 0.9706 0.9762 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 F24 mock treatment 0.186 -0.0262 -0.27 0.165 -0.0159 -0.19 -0.3288 -0.9839 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G01 compound treatment 0.54 0.328 3.44 0.468 0.287 3.43 4.8636 1.0 3039100 ChemDiv3_013861 Clc1cccc(CSCc2ccc(o2)C(=O)NCc3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G02 compound treatment 0.097 -0.115 -1.21 0.099 -0.0819 -0.98 -1.5481 -0.9946 3039101 ChemDiv3_013862 CC(N1CCC(CNC(=S)Nc2ccc(C)cc2)C1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G03 compound treatment 0.327 0.115 1.21 0.25 0.0691 0.83 1.4374 0.983 3120283 ChemDiv3_013863 O=C(NC1CCCCC1)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G04 compound treatment 0.231 0.0188 0.2 0.245 0.0641 0.77 0.6822 0.8614 3039102 ChemDiv3_013864 Cc1ccc(CCNC(=O)c2cc3c(C)nccc3[nH]c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G05 compound treatment 0.269 0.0568 0.6 0.257 0.0761 0.91 1.0659 0.9791 3120284 ChemDiv3_013865 CCOc1ccc(Nc2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G06 compound treatment 0.578 0.366 3.84 0.46 0.279 3.34 5.0781 0.9976 3120285 ChemDiv3_013866 Cc1ccccc1CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NCc4ccco4)/Sc5ccccc25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G07 compound treatment 0.207 -0.00516 -0.05 0.176 -0.00491 -0.06 -0.0798 -0.9992 3039103 ChemDiv3_013867 O=C(CCN1N=C(CCC1=O)c2ccccc2)NCCCN3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G08 compound treatment 0.59 0.378 3.97 0.56 0.379 4.54 6.0132 0.9978 3120286 ChemDiv3_013868 Cc1ccc(cc1)c2nn(CC(=O)NC3CCCc4ccccc34)c(=O)c5ccccc25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G09 compound treatment 0.408 0.196 2.06 0.34 0.159 1.9 2.8004 0.9993 3039104 ChemDiv3_013869 Fc1ccc(CN2CCCN(CC(=O)NC3CCCCCC3)C2=O)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G10 compound treatment 0.149 -0.0632 -0.66 0.151 -0.0299 -0.36 -0.722 -0.958 3120287 ChemDiv3_013870 Fc1cc(Br)ccc1NC(=O)CSCCc2ccccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G11 compound treatment 0.395 0.183 1.92 0.33 0.149 1.78 2.6192 0.9993 3120288 ChemDiv3_013871 O=C(CN1C(=O)/C(=C\c2ccccc2)/Oc3ccccc13)NC4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G12 compound treatment 0.295 0.0828 0.87 0.232 0.0511 0.61 1.0475 0.9851 3039105 ChemDiv3_013872 OCc1nc2cc(ccc2[nH]1)S(=O)(=O)c3ccc4[nH]c(CO)nc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G13 compound treatment 0.243 0.0308 0.32 0.256 0.0751 0.9 0.8644 0.905 3120467 ChemDiv3_013873 Cc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)n3ccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G14 compound treatment 0.325 0.113 1.19 0.312 0.131 1.57 1.9471 0.9905 3039106 ChemDiv3_013874 CC(=O)Nc1ccc(NC(=O)CCCc2c[nH]c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G15 compound treatment 0.337 0.125 1.31 0.271 0.0901 1.08 1.6894 0.9953 3120468 ChemDiv3_013875 O=C(NCc1ccccc1)c2ccc3S/C(=C\c4ccccc4)/C(=O)Nc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G16 compound treatment 0.3 0.0878 0.92 0.216 0.0351 0.42 0.9493 0.9365 3120469 ChemDiv3_013876 Oc1ccc(CCNC(=O)c2ccc3ccccc3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G17 compound treatment 0.828 0.616 6.47 0.724 0.543 6.5 9.1682 1.0 3039107 ChemDiv3_013877 COc1ccc(/C=C\2/Sc3ccc(cc3NC2=O)C(=O)N(C)C4CCCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G18 compound treatment 0.182 -0.0302 -0.32 0.16 -0.0209 -0.25 -0.4008 -0.9932 3120470 ChemDiv3_013878 COc1ccc(NC(=O)c2cccnc2SC)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G19 compound treatment 0.239 0.0268 0.28 0.18 -9.06E-4 -0.01 0.1917 0.6794 3120471 ChemDiv3_013879 CCOc1ccc(NC(=O)N(CCc2ccncc2)C(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G20 compound treatment 0.345 0.133 1.4 0.295 0.114 1.37 1.9518 0.9999 1408397 ChemDiv3_013880 COc1ccc(NC(=O)Cc2cccc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G21 compound treatment 0.907 0.695 7.3 0.879 0.698 8.35 11.0662 0.9977 3120472 ChemDiv3_013881 Cc1ccc(cc1)C2CCN(C2)C(=S)Nc3ccccc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G22 compound treatment 0.6 0.388 4.07 0.564 0.383 4.58 6.1214 0.9983 3039108 ChemDiv3_013882 Cc1ccc(cc1)C(=O)CCC(=O)Nc2cccc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G23 mock treatment 0.203 -0.00916 -0.1 0.177 -0.00391 -0.05 -0.101 -0.9451 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 G24 mock treatment 0.178 -0.0342 -0.36 0.212 0.0311 0.37 0.0094 0.0182 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H01 compound treatment 0.272 0.0598 0.63 0.249 0.0681 0.81 1.0205 0.9918 3120473 ChemDiv3_013883 Oc1ccc(NC(=O)CCCC(=O)c2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H02 compound treatment 0.49 0.278 2.92 0.521 0.34 4.07 4.9406 0.9867 1419333 ChemDiv3_013884 CNC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N3CCC(C)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H03 compound treatment 0.396 0.184 1.93 0.385 0.204 2.44 3.092 0.9932 3039109 ChemDiv3_013885 FC(F)(F)c1ccccc1CNC(=O)/C=C/c2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H04 compound treatment 0.134 -0.0782 -0.82 0.13 -0.0509 -0.61 -1.0111 -0.9892 1637040 ChemDiv3_013886 CCN(CC)c1nc(nc2ccccc12)c3ccccc3F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H05 compound treatment 0.612 0.4 4.2 0.535 0.354 4.24 5.9651 1.0 3120474 ChemDiv3_013887 CC1(CC2CC(C)(C)C1)CN2C(=O)CN3C(=O)c4ccccc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H06 compound treatment 0.055 -0.157 -1.65 0.052 -0.129 -1.54 -2.2577 -0.9994 1451213 ChemDiv3_013888 CCc1nc2ccccc2c(=O)n1NC(=O)c3c(O)c4ccccc4n(CC)c3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H07 compound treatment 0.537 0.325 3.41 0.449 0.268 3.21 4.6806 0.9995 1557141 ChemDiv3_013889 Clc1ccccc1N2C(=O)C(Cc3c[nH]c4ccccc34)NC2=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H08 compound treatment 0.358 0.146 1.53 0.274 0.0931 1.11 1.8707 0.9878 1415454 ChemDiv3_013890 COc1ccc(NC(=O)Cc2nn(C)c(=O)c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H09 compound treatment 0.172 -0.0402 -0.42 0.161 -0.0199 -0.24 -0.4666 -0.9634 3039110 ChemDiv3_013891 CN1/C(=C\C(=O)C2CCCCC2)/C(C)(C)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H10 compound treatment 0.116 -0.0962 -1.01 0.125 -0.0559 -0.67 -1.1871 -0.98 3120475 ChemDiv3_013892 CC1CCCCN1c2ncnc3sc(C(=O)NCCC4=CCCCC4)c(C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H11 compound treatment 1.122 0.91 9.56 1.074 0.893 10.69 14.3127 0.9984 3039111 ChemDiv3_013893 COC(=O)c1cc(nc2ccc(C)cc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H12 compound treatment 0.398 0.186 1.95 0.338 0.157 1.88 2.7092 0.9998 3120476 ChemDiv3_013894 CCN(CC)C(=O)c1sc2ncn(CC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H13 compound treatment 0.186 -0.0262 -0.27 0.179 -0.00191 -0.02 -0.2104 -0.7632 3120477 ChemDiv3_013895 OC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H14 compound treatment 0.18 -0.0322 -0.34 0.215 0.0341 0.41 0.0496 0.0937 3039112 ChemDiv3_013896 Brc1cc(sc1Br)S(=O)(=O)NCCCN2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H15 compound treatment 0.334 0.122 1.28 0.295 0.114 1.37 1.8701 0.9995 1357362 ChemDiv3_013897 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCCC4=CCCCC4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H16 compound treatment 0.278 0.0658 0.69 0.279 0.0981 1.17 1.3189 0.9682 1534773 ChemDiv3_013898 CCCNC(=O)c1ccc2n(cnc2c1)c3cc(OC)ccc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H17 compound treatment 0.323 0.111 1.16 0.253 0.0721 0.86 1.4331 0.9891 3120478 ChemDiv3_013899 COc1cc(OC)c(cc1OC)C2C3=C(CC(C)(C)CC3=O)Nc4nc5ccccc5n24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H18 compound treatment 0.163 -0.0492 -0.52 0.141 -0.0399 -0.48 -0.7027 -0.9992 1703943 ChemDiv3_013900 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1c3ccc(Br)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H19 compound treatment 0.464 0.252 2.65 0.454 0.273 3.27 4.1807 0.9945 1865647 ChemDiv3_013901 COc1ccc(/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccc(OC)cc5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H20 compound treatment 0.438 0.226 2.37 0.385 0.204 2.44 3.4039 0.9999 1356163 ChemDiv3_013902 COc1ccc(cc1OC)C(=O)NCC2COc3ccccc3O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H21 compound treatment 0.525 0.313 3.29 0.486 0.305 3.65 4.9045 0.9986 3120480 ChemDiv3_013903 CCOC(=O)C1=CN(Cc2ccc(F)cc2)C=C(C1c3ccc(cc3)C(F)(F)F)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H22 compound treatment 0.133 -0.0792 -0.83 0.13 -0.0509 -0.61 -1.0185 -0.9883 3039113 ChemDiv3_013904 Brc1ccc(NC(=O)CNC(=O)c2ccco2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H23 mock treatment 0.251 0.0388 0.41 0.211 0.0301 0.36 0.5431 0.9981 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 H24 mock treatment 0.189 -0.0232 -0.24 0.177 -0.00391 -0.05 -0.205 -0.8278 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I01 compound treatment 1.345 1.13 11.9 1.317 1.14 13.59 18.0246 0.9978 3120481 ChemDiv3_013905 Clc1cccc(CSCc2ccc(o2)C(=O)NC3CCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I02 compound treatment 0.348 0.136 1.43 0.339 0.158 1.89 2.3463 0.9903 3120482 ChemDiv3_013906 CCN1CCN(CCNC(=O)c2ccc3S/C(=C/c4cccc(Cl)c4)/C(=O)Nc3c2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I03 compound treatment 0.398 0.186 1.95 0.328 0.147 1.76 2.6246 0.9987 3039114 ChemDiv3_013907 CCC(C)NC(=O)c1ccc(/C=C\2/Sc3ccccc3NC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I04 compound treatment 0.302 0.0898 0.94 0.191 0.0101 0.12 0.7526 0.7912 3120483 ChemDiv3_013908 Cc1nccc2[nH]c(=O)c(cc12)C(=O)NCCCN3CCC(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I05 compound treatment 0.222 0.00984 0.1 0.192 0.0111 0.13 0.167 0.9924 3039115 ChemDiv3_013909 Fc1ccccc1CN2CCCN(C2)C(=O)Nc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I06 compound treatment 0.332 0.12 1.26 0.312 0.131 1.57 1.9991 0.9941 3120484 ChemDiv3_013910 Clc1ccccc1c2cc(=O)n(CC(=O)NC3CC3)c4CCCc42 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I07 compound treatment 0.279 0.0668 0.7 0.206 0.0251 0.3 0.7087 0.9282 3039116 ChemDiv3_013911 O=C(c1ccc(cc1)N2CCCC2=O)n3ccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I08 compound treatment 0.29 0.0778 0.82 0.221 0.0401 0.48 0.9173 0.9677 3120485 ChemDiv3_013912 CC1N=C(c2ccccc2F)c3cc(Cl)ccc3N(Cc4nc(oc4C)c5cccc(C)c5)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I09 compound treatment 0.124 -0.0882 -0.93 0.124 -0.0569 -0.68 -1.1361 -0.9886 3120486 ChemDiv3_013913 CCOC(=O)c1ccc(NC(=S)N2CCCN(Cc3cc(C)ccc3C)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I10 compound treatment 0.282 0.0698 0.73 0.234 0.0531 0.64 0.9679 0.9974 3039117 ChemDiv3_013914 O=C(CSCCc1ccccn1)Nc2cccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I11 compound treatment 0.346 0.134 1.41 0.336 0.155 1.86 2.3061 0.9906 3120487 ChemDiv3_013915 O=C(CN1C(=O)/C(=C\c2ccccc2)/Oc3ccccc13)NCCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I12 compound treatment 0.242 0.0298 0.31 0.302 0.121 1.45 1.2461 0.8406 3039118 ChemDiv3_013916 O=C(CC1CC2CCC1C2)NC(c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I13 compound treatment 0.281 0.0688 0.72 0.272 0.0911 1.09 1.2819 0.9801 3120488 ChemDiv3_013917 Cc1nn2c(cc(C)nc2c1c3ccc(Cl)cc3)N4CCN(CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I14 compound treatment 0.247 0.0348 0.37 0.202 0.0211 0.25 0.4372 0.9835 3039119 ChemDiv3_013918 O=C(CCCc1c[nH]c2ccccc12)NC3=NCCS3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I15 compound treatment 0.243 0.0308 0.32 0.237 0.0561 0.67 0.7036 0.9442 3120489 ChemDiv3_013919 O=C(NC1CC1)c2ccc3S/C(=C\c4ccccc4)/C(=O)Nc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I16 compound treatment 0.293 0.0808 0.85 0.269 0.0881 1.05 1.3457 0.9943 3120658 ChemDiv3_013920 COc1cc(CCC(=O)NC2CCCCC2)cc(OC)c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I17 compound treatment 0.279 0.0668 0.7 0.255 0.0741 0.89 1.1233 0.9933 3039120 ChemDiv3_013921 COc1ccc(OC)c(/C=C\C(=O)NCC(=O)O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I18 compound treatment 0.377 0.165 1.73 0.336 0.155 1.86 2.5363 0.9994 3120659 ChemDiv3_013922 COc1ccc(NC(=O)c2ccc(C)c(I)c2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I19 compound treatment 0.226 0.0138 0.15 0.198 0.0171 0.2 0.2474 0.986 3039121 ChemDiv3_013923 CC(C)N(CCc1ccncc1)C(=O)Nc2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I20 compound treatment 0.297 0.0848 0.89 0.296 0.115 1.38 1.6038 0.9778 3120660 ChemDiv3_013924 O=C(Cc1cccc2ccccc12)Nc3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I21 compound treatment 0.529 0.317 3.33 0.481 0.3 3.59 4.8919 0.9993 3039122 ChemDiv3_013925 CC(C)NC(=S)N1CCC(C1)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I22 compound treatment 0.638 0.426 4.47 0.577 0.396 4.74 6.5135 0.9996 3120661 ChemDiv3_013926 Clc1ccc(NC(=O)CCCC(=O)c2ccccc2)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I23 mock treatment 0.212 -1.56E-4 0.0 0.186 0.00509 0.06 0.0419 0.6878 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 I24 mock treatment 0.222 0.00984 0.1 0.172 -0.00891 -0.11 -0.0022 -0.0151 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J01 compound treatment 0.265 0.0528 0.55 0.254 0.0731 0.87 1.0108 0.9759 3120662 ChemDiv3_013927 CC(=O)Nc1ccc(NC(=O)CCC(=O)c2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J02 compound treatment 0.332 0.12 1.26 0.278 0.0971 1.16 1.7114 0.9992 1226624 ChemDiv3_013928 O=C(Nc1ccccc1C(=O)N2CCCCCC2)c3cccc(c3)S(=O)(=O)N4CCCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J03 compound treatment 0.33 0.118 1.24 0.229 0.0481 0.58 1.282 0.9393 3039123 ChemDiv3_013929 Cc1nn(C)c(C)c1NC(=O)/C=C/c2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J04 compound treatment 0.102 -0.11 -1.16 0.1 -0.0809 -0.97 -1.5026 -0.9961 3039124 ChemDiv3_013930 COc1ccc(cc1)c2cn(c3SCC[n+]23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J05 compound treatment 0.317 0.105 1.1 0.249 0.0681 0.81 1.3547 0.989 1657713 ChemDiv3_013931 O=C(CN1C(=O)c2ccccc2C1=O)NCc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J06 compound treatment 0.396 0.184 1.93 0.39 0.209 2.5 3.1343 0.9918 1499484 ChemDiv3_013932 CCNC(=O)c1c(O)c2cccc3CCn(c1=O)c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J07 compound treatment 0.815 0.603 6.33 0.81 0.629 7.53 9.7992 0.9963 3039345 ChemDiv3_013933 COC(=O)C1=CN(Cc2ccc(C)cc2)C=C(C1c3ccc(C)s3)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J08 compound treatment 0.362 0.15 1.57 0.307 0.126 1.51 2.1796 0.9998 1267708 ChemDiv3_013934 COc1ccc(cc1)N2CCN(CC2)C(=O)Cc3nn(C)c(=O)c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J09 compound treatment 0.039 -0.173 -1.82 0.04 -0.141 -1.69 -2.478 -0.9993 3039347 ChemDiv3_013935 CC(C)C(=O)c1c(O)c2ccccc2oc1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J10 compound treatment 0.281 0.0688 0.72 0.245 0.0641 0.77 1.0535 0.9996 1267288 ChemDiv3_013936 COc1cc(OC)c(NC(=O)c2sc3ncnc(N4CCCCC4C)c3c2C)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J11 compound treatment 0.371 0.159 1.67 0.346 0.165 1.98 2.5764 0.9965 3039349 ChemDiv3_013937 Oc1nc(CSCC(=O)NC2CCCCCC2)nc3n(Cc4ccc(F)cc4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J12 compound treatment 0.378 0.166 1.74 0.355 0.174 2.08 2.7045 0.996 1131500 ChemDiv3_013938 CCN(CC)c1ncnc2sc(C(=O)N(C)C3CCCCC3)c(C)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J13 compound treatment 0.351 0.139 1.46 0.394 0.213 2.55 2.8339 0.9649 1144209 ChemDiv3_013939 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCCC4=CCCCC4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J14 compound treatment 0.1 -0.112 -1.18 0.093 -0.0879 -1.05 -1.5766 -0.9984 1118892 ChemDiv3_013940 COc1ccccc1n2cnc3cc(ccc23)C(=O)NC4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J15 compound treatment 0.339 0.127 1.33 0.286 0.105 1.26 1.8311 0.9996 1196467 ChemDiv3_013941 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NC4CCCCC4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J16 compound treatment 0.18 -0.0322 -0.34 0.198 0.0171 0.2 -0.0942 -0.2386 1134270 ChemDiv3_013942 CCCNC(=O)c1ccc2n(cnc2c1)c3ccc(OCc4ccccc4)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J17 compound treatment 0.3 0.0878 0.92 0.247 0.0661 0.79 1.2115 0.9971 3120663 ChemDiv3_013943 COc1ccc(cc1)C2C3=C(CCCC3=O)Nc4nc5ccccc5n24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J18 compound treatment 0.408 0.196 2.06 0.401 0.22 2.63 3.3165 0.9925 1702176 ChemDiv3_013944 Cc1n[nH]c2nc(SCC(=O)N3CCCC3)n(c4ccc(Br)cc4)c(=N)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J19 compound treatment 0.282 0.0698 0.73 0.261 0.0801 0.96 1.1963 0.9913 1865902 ChemDiv3_013945 Cc1ccc(/C=C/2\CCCC3=C2Nc4nnnn4C3c5ccc(C)cc5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J20 compound treatment 0.045 -0.167 -1.76 0.045 -0.136 -1.63 -2.3912 -0.9993 1118565 ChemDiv3_013946 O=C(Oc1ccc2sc(=O)oc2c1)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J21 compound treatment 0.462 0.25 2.62 0.48 0.299 3.58 4.3858 0.9884 3120665 ChemDiv3_013947 CCOC(=O)C1=CN(C)C=C(C1c2cc(Br)c(O)c(OC)c2)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J22 compound treatment 0.313 0.101 1.06 0.277 0.0961 1.15 1.5619 0.9992 3039356 ChemDiv3_013948 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)C3(CC3)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J23 mock treatment 0.244 0.0318 0.33 0.21 0.0291 0.35 0.4826 0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 J24 mock treatment 0.201 -0.0112 -0.12 0.164 -0.0169 -0.2 -0.2259 -0.9663 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K01 compound treatment 0.228 0.0158 0.17 0.2 0.0191 0.23 0.2792 0.9879 3120666 ChemDiv3_013949 COC(CNC(=O)c1ccc(CS(=O)(=O)Cc2ccc(Cl)cc2)o1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K02 compound treatment 0.94 0.728 7.64 0.906 0.725 8.68 11.5397 0.998 3120667 ChemDiv3_013950 COC(CNC(=O)c1ccc(/C=C\2/Sc3ccccc3N(Cc4cccc(C)c4)C2=O)cc1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K03 compound treatment 0.236 0.0238 0.25 0.186 0.00509 0.06 0.2202 0.8543 3039359 ChemDiv3_013951 CC(=O)N1CCC(CC1)N(CCN2CCOCC2)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K04 compound treatment 0.278 0.0658 0.69 0.21 0.0291 0.35 0.7351 0.9495 3120668 ChemDiv3_013952 CC1CCC(CC1)NC(=O)c2cc3c(C)nccc3[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K05 compound treatment 0.367 0.155 1.63 0.348 0.167 2.0 2.5636 0.9948 3039361 ChemDiv3_013953 CCCCN(C1CCN(CC1)C(=O)C)C(=S)Nc2ccccc2CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K06 compound treatment 0.334 0.122 1.28 0.262 0.0811 0.97 1.5909 0.9907 3039415 ChemDiv3_013954 CCCNC(=O)Cn1c2CCCc2c(cc1=O)c3ccccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K07 compound treatment 0.393 0.181 1.9 0.35 0.169 2.02 2.7736 0.9995 3039416 ChemDiv3_013955 Cc1ccc(CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NCc4cccnc4)/Oc5ccccc25)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K08 compound treatment 0.293 0.0808 0.85 0.245 0.0641 0.77 1.1426 0.9987 3039418 ChemDiv3_013956 CCCNC(=O)c1ccc(CS(=O)(=O)c2ccc(OC)cc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K09 compound treatment 0.25 0.0378 0.4 0.243 0.0621 0.74 0.8064 0.9571 3039419 ChemDiv3_013957 CC(C)CCNC(=O)c1ccc(CS(=O)(=O)Cc2ccc(F)cc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K10 compound treatment 0.616 0.404 4.24 0.543 0.362 4.33 6.0625 0.9999 3039421 ChemDiv3_013958 COc1ccccc1NC(=O)c2c(NCc3sccc3C)sc4CCCCc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K11 compound treatment 0.308 0.0958 1.01 0.28 0.0991 1.19 1.5501 0.9967 3039422 ChemDiv3_013959 Brc1ccccc1/C=C\2/Oc3ccccc3N(CC(=O)NC4CC4)C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K12 compound treatment 0.702 0.49 5.14 0.622 0.441 5.28 7.3695 0.9999 3120669 ChemDiv3_013960 Cc1cccc(NC(=O)CC2CC3CCC2C3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K13 compound treatment 0.263 0.0508 0.53 0.259 0.0781 0.93 1.0383 0.9648 3120670 ChemDiv3_013961 CCC(C)NC(=O)CCN1N=C(CCC1=O)c2ccc(CC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K14 compound treatment 0.135 -0.0772 -0.81 0.145 -0.0359 -0.43 -0.8768 -0.9559 3039425 ChemDiv3_013962 FC(F)(F)c1ccccc1CNC(=O)CCCc2c[nH]c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K15 compound treatment 0.255 0.0428 0.45 0.232 0.0511 0.61 0.7504 0.9886 3120671 ChemDiv3_013963 OC(=O)CNC(=O)/C=C/c1cccc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K16 compound treatment 0.227 0.0148 0.16 0.233 0.0521 0.62 0.551 0.8576 3039427 ChemDiv3_013964 COc1cc(CCC(=O)NCc2ccccc2)cc(OC)c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K17 compound treatment 0.325 0.113 1.19 0.316 0.135 1.62 1.9809 0.9884 3120672 ChemDiv3_013965 COC(CNC(=O)c1ccc2S/C(=C/c3cccc(OC)c3)/C(=O)Nc2c1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K18 compound treatment 0.218 0.00584 0.06 0.189 0.00809 0.1 0.1119 0.9758 3039429 ChemDiv3_013966 Cc1ccc(cc1I)C(=O)Nc2ccc(Br)cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K19 compound treatment 0.117 -0.0952 -1.0 0.098 -0.0829 -0.99 -1.4081 -1.0 3120673 ChemDiv3_013967 CC(C)N(CCc1ccncc1)C(=S)NC2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K20 compound treatment 0.379 0.167 1.75 0.367 0.186 2.23 2.8134 0.993 3120674 ChemDiv3_013968 COc1ccc(C(=O)N(CCc2ccccc2)Cc3ccccc3)c(OC)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K21 compound treatment 0.483 0.271 2.84 0.486 0.305 3.65 4.5926 0.9924 3039431 ChemDiv3_013969 Cc1ccc(cc1)C2CCN(C2)C(=S)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K22 compound treatment 0.359 0.147 1.54 0.346 0.165 1.98 2.4873 0.9925 3120675 ChemDiv3_013970 O=C(CCCC(=O)c1ccccc1)Nc2ccc3CCCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K23 mock treatment 0.19 -0.0222 -0.23 0.172 -0.00891 -0.11 -0.2399 -0.9373 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 K24 mock treatment 0.185 -0.0272 -0.29 0.178 -0.00291 -0.03 -0.2263 -0.7875 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L01 compound treatment 0.45 0.238 2.5 0.421 0.24 2.87 3.7976 0.9976 3039434 ChemDiv3_013971 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L02 compound treatment 0.239 0.0268 0.28 0.232 0.0511 0.61 0.6316 0.9382 1182957 ChemDiv3_013972 CCN(CC)C(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N(CC)CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L03 compound treatment 0.511 0.299 3.14 0.401 0.22 2.63 4.0814 0.9962 3039436 ChemDiv3_013973 O=C(NCc1ccco1)/C=C/c2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L04 compound treatment 0.213 8.44E-4 0.01 0.203 0.0221 0.26 0.1932 0.7304 1123777 ChemDiv3_013974 CCCn1c(=O)c(C(=O)NC2(CC3CC4CC(C3)C2)C4)c(O)c5ccccc15 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L05 compound treatment 0.494 0.282 2.96 0.416 0.235 2.81 4.082 0.9997 3039438 ChemDiv3_013975 O=C(NC1=NCCS1)c2ccccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L06 compound treatment 0.304 0.0918 0.96 0.265 0.0841 1.01 1.3935 0.9998 3120676 ChemDiv3_013976 NNC(=O)c1c(O)c2CCCCc2[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L07 compound treatment 0.33 0.118 1.24 0.307 0.126 1.51 1.9419 0.9952 1158928 ChemDiv3_013977 CCOC(=O)C1=C(C)N(C)C(=C(C1c2ccccc2F)C(=O)OCC)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L08 compound treatment 0.332 0.12 1.26 0.313 0.132 1.58 2.0076 0.9936 1153961 ChemDiv3_013978 CCn1c(=O)n(CC(=O)N(C)Cc2ccccc2)c(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L09 compound treatment 0.124 -0.0882 -0.93 0.064 -0.117 -1.4 -1.6437 -0.9799 3039500 ChemDiv3_013979 Oc1c(C(=O)CC2CCCCC2)c(=O)oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L10 compound treatment 1.378 1.17 12.24 1.397 1.22 14.55 18.9465 0.9963 1480114 ChemDiv3_013980 CC1CCN(CC1)c2ncnc3sc(C(=O)Nc4ccc(F)cc4F)c(C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L11 compound treatment 0.408 0.196 2.06 0.405 0.224 2.68 3.3503 0.9914 3039502 ChemDiv3_013981 Cc1ccc(cc1Cl)n2c(SCc3ccccc3)nnc2c4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L12 compound treatment 0.399 0.187 1.96 0.402 0.221 2.65 3.2581 0.9892 1401832 ChemDiv3_013982 CCN(CC)c1nc(C)nc2sc(C(=O)Nc3cc(Cl)ccc3OC)c(C)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L13 compound treatment 0.443 0.231 2.42 0.403 0.222 2.66 3.5933 0.999 1393537 ChemDiv3_013983 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCC(C)CC4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L14 compound treatment 0.403 0.191 2.0 0.424 0.243 2.91 3.4739 0.9835 1519772 ChemDiv3_013984 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NCc4ccccc4OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L15 compound treatment 0.285 0.0728 0.77 0.257 0.0761 0.91 1.1847 0.9963 1284089 ChemDiv3_013985 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCC5(CC4)OCCO5)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L16 compound treatment 0.124 -0.0882 -0.93 0.126 -0.0549 -0.66 -1.1192 -0.9859 1380751 ChemDiv3_013986 Fc1cccc(c1)n2cnc3cc(ccc23)C(=O)NCCC4=CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L17 compound treatment 0.296 0.0838 0.88 0.268 0.0871 1.04 1.3595 0.9965 3120860 ChemDiv3_013987 Clc1cccc(c1)C2C3=C(CCCC3=O)Nc4nc5ccccc5n24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L18 compound treatment 0.416 0.204 2.14 0.425 0.244 2.92 3.5789 0.9883 1653478 ChemDiv3_013988 Cc1n[nH]c2nc(SCc3cc(=O)n4ccccc4n3)n(c5cccc(Cl)c5C)c(=N)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L19 compound treatment 0.139 -0.0732 -0.77 0.169 -0.0119 -0.14 -0.644 -0.8242 3120861 ChemDiv3_013989 CC(C)c1ccc(cc1)C2=CC(c3ccc(C)cc3)n4ncnc4N2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L20 compound treatment 0.349 0.137 1.44 0.294 0.113 1.35 1.9731 0.9995 3039508 ChemDiv3_013990 FC(F)(F)c1cccc(c1)C(=O)N2CC(=O)N(CCc3ccccc3)C(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L21 compound treatment 0.717 0.505 5.3 0.737 0.556 6.65 8.4539 0.9937 3120862 ChemDiv3_013991 COC(=O)C1=CN(Cc2ccc(OC)cc2)C=C(C1c3ccc(OC)cc3)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L22 compound treatment 0.267 0.0548 0.58 0.269 0.0881 1.05 1.1526 0.9596 3039510 ChemDiv3_013992 Cc1n[nH]c(C)c1S(=O)(=O)N2CCc3ccccc3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L23 mock treatment 0.264 0.0518 0.54 0.203 0.0221 0.26 0.5719 0.9449 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 L24 mock treatment 0.177 -0.0352 -0.37 0.159 -0.0219 -0.26 -0.4464 -0.9859 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M01 compound treatment 0.263 0.0508 0.53 0.218 0.0371 0.44 0.6914 0.9958 3120863 ChemDiv3_013993 CC(C)CCN(C1CCN(CC1)C(=O)C)C(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M02 compound treatment 0.823 0.611 6.42 0.753 0.572 6.84 9.3764 0.9995 3120864 ChemDiv3_013994 Cc1cccc(CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NCc4cccnc4)/Sc5ccccc25)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M03 compound treatment 0.122 -0.0902 -0.95 0.103 -0.0779 -0.93 -1.3286 -1.0 3039512 ChemDiv3_013995 COc1ccc(NC(=S)N2CCCN(Cc3ccc(F)cc3)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M04 compound treatment 0.433 0.221 2.32 0.345 0.164 1.96 3.0284 0.9966 3120865 ChemDiv3_013996 COc1ccc(/C=C\2/Oc3ccccc3N(CC(=O)NC4CCCc5ccccc45)C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M05 compound treatment 0.218 0.00584 0.06 0.156 -0.0249 -0.3 -0.1673 -0.5499 3039514 ChemDiv3_013997 CCOc1ccc(NC(=O)N(CCN2CCOCC2)Cc3ccc4N(CC)CCCc4c3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M06 compound treatment 0.409 0.197 2.07 0.299 0.118 1.41 2.461 0.9828 3120866 ChemDiv3_013998 CCOc1ccc(cc1)c2nc(CSCC(=O)NC3CCCC3)c(C)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M07 compound treatment 0.274 0.0618 0.65 0.242 0.0611 0.73 0.9761 0.9983 3120867 ChemDiv3_013999 COC(CN(C)C(=O)c1cn(C)c2ccc(cc2c1=O)S(=O)(=O)N3CCOCC3)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M08 compound treatment 0.394 0.182 1.91 0.34 0.159 1.9 2.6964 1.0 3039575 ChemDiv3_014000 O=C(N1CCCC1)c2ccc3S/C(=C\c4ccccc4)/C(=O)Nc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M09 compound treatment 0.183 -0.0292 -0.31 0.209 0.0281 0.34 0.0211 0.0465 3039577 ChemDiv3_014001 O=C(CC1Nc2ccccc2NC1=O)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M10 compound treatment 0.393 0.181 1.9 0.347 0.166 1.99 2.7482 0.9997 3039578 ChemDiv3_014002 CCOC(=O)c1ccc(NC(=O)c2c(NCc3ccc(C)o3)sc4CCCCc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M11 compound treatment 0.14 -0.0722 -0.76 0.116 -0.0649 -0.78 -1.085 -0.9999 3039580 ChemDiv3_014003 Cc1ccccc1NC(=S)N(CCCN2CCCC2)Cc3cccn3Cc4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M12 compound treatment 0.307 0.0948 1.0 0.236 0.0551 0.66 1.1705 0.9799 3039581 ChemDiv3_014004 FC(F)(F)c1ccccc1CNC(=O)CC2CC3CCC2C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M13 compound treatment 0.479 0.267 2.8 0.495 0.314 3.76 4.639 0.9896 3120868 ChemDiv3_014005 NC(=O)C1CCN(CC1)C(=O)c2ccc(/C=C\3/Oc4ccccc4N(Cc5ccccc5F)C3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M14 compound treatment 0.492 0.28 2.94 0.458 0.277 3.32 4.4225 0.9982 3039583 ChemDiv3_014006 Fc1ccccc1CCNC(=O)c2ccc3ccccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M15 compound treatment 0.251 0.0388 0.41 0.273 0.0921 1.1 1.0676 0.9086 3039585 ChemDiv3_014007 CCc1ccccc1NC(=S)N2CCC(CC2)N(C)CCN3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M16 compound treatment 0.197 -0.0152 -0.16 0.207 0.0261 0.31 0.1082 0.3088 3120869 ChemDiv3_014008 COc1ccc(NC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M17 compound treatment 0.548 0.336 3.53 0.515 0.334 4.0 5.3206 0.9981 3120870 ChemDiv3_014009 COc1cccc(/C=C\2/Sc3ccc(cc3NC2=O)C(=O)N4CC(C)CC(C)C4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M18 compound treatment 0.307 0.0948 1.0 0.273 0.0921 1.1 1.4835 0.9987 3039587 ChemDiv3_014010 Cc1ccc(cc1I)C(=O)NC2CCCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M19 compound treatment 0.087 -0.125 -1.31 0.072 -0.109 -1.3 -1.8508 -1.0 3120871 ChemDiv3_014011 CC(C)N(CCc1ccncc1)C(=S)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M20 compound treatment 0.521 0.309 3.24 0.445 0.264 3.16 4.5279 0.9999 3039589 ChemDiv3_014012 COc1ccc(C(=O)NCc2ccccc2)c(OC)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M21 compound treatment 0.969 0.757 7.95 0.917 0.736 8.81 11.8482 0.9987 3120872 ChemDiv3_014013 COc1ccc(cc1OC)C2CCCN2C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M22 compound treatment 0.292 0.0798 0.84 0.27 0.0891 1.07 1.3467 0.9929 3039591 ChemDiv3_014014 Cc1cc(NC(=O)CCCC(=O)c2ccccc2)n[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M23 mock treatment 0.204 -0.00816 -0.09 0.166 -0.0149 -0.18 -0.1867 -0.9435 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 M24 mock treatment 0.166 -0.0462 -0.48 0.15 -0.0309 -0.37 -0.6043 -0.9911 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N01 compound treatment 0.263 0.0508 0.53 0.275 0.0941 1.13 1.1736 0.9419 3120873 ChemDiv3_014015 COc1ccc(cc1)N2CCN(CC2)C(=O)CCC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N02 compound treatment 0.355 0.143 1.5 0.344 0.163 1.95 2.4406 0.9916 1672196 ChemDiv3_014016 COc1ccc(cc1)C(=O)NC(c2ccc(C)cc2)c3cc(Cl)c4cccnc4c3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N03 compound treatment 0.392 0.18 1.89 0.4 0.219 2.62 3.1892 0.9871 1611897 ChemDiv3_014017 Cc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N04 compound treatment 0.322 0.11 1.15 0.282 0.101 1.21 1.671 0.9997 1269317 ChemDiv3_014018 Oc1c(CC(=O)NCc2ccccc2Cl)c(=O)[nH]c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N05 compound treatment 0.359 0.147 1.54 0.272 0.0911 1.09 1.8612 0.9856 3039594 ChemDiv3_014019 Cc1cc(Br)ccc1NC(=O)c2ccccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N06 compound treatment 0.179 -0.0332 -0.35 0.17 -0.0109 -0.13 -0.3385 -0.9103 3120874 ChemDiv3_014020 CCn1c(=O)c(C2=Nc3ccccc3S(=O)(=O)N2)c(O)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N07 compound treatment 0.964 0.752 7.9 0.89 0.709 8.48 11.5826 0.9994 1592049 ChemDiv3_014021 CCOC(=O)C1=C(C)N(C)C(=C(C1c2ccc(C)s2)C(=O)OCC)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N08 compound treatment 0.183 -0.0292 -0.31 0.17 -0.0109 -0.13 -0.3088 -0.9277 1473031 ChemDiv3_014022 CCn1c(=O)n(CC(=O)N2CC(C)CC(C)C2)c(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N09 compound treatment 0.042 -0.17 -1.79 0.041 -0.14 -1.67 -2.4473 -0.9995 3039597 ChemDiv3_014023 Oc1c(C(=O)C2CCC2)c(=O)oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N10 compound treatment 0.352 0.14 1.47 0.355 0.174 2.08 2.5114 0.9854 1571851 ChemDiv3_014024 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N11 compound treatment 0.313 0.101 1.06 0.27 0.0891 1.07 1.5027 1.0 3039657 ChemDiv3_014025 NC(=O)CSc1nnc(c2cccnc2)n1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N12 compound treatment 0.579 0.367 3.85 0.518 0.337 4.03 5.5762 0.9997 1449739 ChemDiv3_014026 CCN(CC)c1nc(C)nc2sc(C(=O)N3CCCCCC3)c(C)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N13 compound treatment 0.291 0.0788 0.83 0.226 0.0451 0.54 0.967 0.9785 1496672 ChemDiv3_014027 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N14 compound treatment 0.095 -0.117 -1.23 0.1 -0.0809 -0.97 -1.5545 -0.9929 1664336 ChemDiv3_014028 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NC4CCCCC4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N15 compound treatment 0.306 0.0938 0.99 0.31 0.129 1.54 1.7891 0.9765 3039661 ChemDiv3_014029 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4Cl)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N16 compound treatment 0.157 -0.0552 -0.58 0.155 -0.0259 -0.31 -0.6288 -0.9571 1520077 ChemDiv3_014030 COC(CNC(=O)c1ccc2n(c(C)nc2c1)c3cc(Cl)ccc3OC)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N17 compound treatment 0.291 0.0788 0.83 0.3 0.119 1.42 1.5931 0.9667 3039662 ChemDiv3_014031 CCC1=C(C(c2cc(OC)c(OC)cc2OC)n3ncnc3N1)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N18 compound treatment 0.309 0.0968 1.02 0.285 0.104 1.25 1.5999 0.9949 1180590 ChemDiv3_014032 CCOc1ccc(cc1)n2c(SCC(=O)NCc3ccco3)nc4[nH]nc(C)c4c2=N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N19 compound treatment 0.129 -0.0832 -0.87 0.126 -0.0549 -0.66 -1.0821 -0.9901 3039664 ChemDiv3_014033 Cc1ccc(cc1C)C2CC(c3c(F)cccc3Cl)n4ncnc4N2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N20 compound treatment 0.269 0.0568 0.6 0.214 0.0331 0.4 0.7021 0.9801 1720516 ChemDiv3_014034 CC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N21 compound treatment 0.575 0.363 3.81 0.519 0.338 4.05 5.555 0.9996 3120875 ChemDiv3_014035 COC(=O)C1=CN(Cc2ccc(Cl)cc2)C=C(C1c3cccc(Cl)c3)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N22 compound treatment 0.305 0.0928 0.98 0.244 0.0631 0.75 1.2233 0.992 3039667 ChemDiv3_014036 Cc1n[nH]c(C)c1S(=O)(=O)N2CCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N23 mock treatment 0.241 0.0288 0.3 0.196 0.0151 0.18 0.3419 0.9694 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 N24 mock treatment 0.183 -0.0292 -0.31 0.159 -0.0219 -0.26 -0.4019 -0.997 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O01 compound treatment 0.374 0.162 1.7 0.343 0.162 1.94 2.5733 0.9978 3120876 ChemDiv3_014037 Cc1ccc(C)c(c1)N2CCN(CC2)C(=O)c3ccc(/C=C/4\Oc5ccccc5NC4=O)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O02 compound treatment 0.483 0.271 2.84 0.372 0.191 2.29 3.6281 0.9941 3039669 ChemDiv3_014038 Cc1cccc(/C=C\2/Oc3ccccc3N(CC(=O)N4CCC5(CC4)OCCO5)C2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O03 compound treatment 0.37 0.158 1.66 0.355 0.174 2.08 2.6451 0.9936 3120877 ChemDiv3_014039 Fc1cccc(/C=C\2/Oc3ccccc3N(CC(=O)N4CCN(CC4)c5ncccn5)C2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O04 compound treatment 1.148 0.936 9.83 1.106 0.925 11.07 14.7765 0.9982 3120878 ChemDiv3_014040 Fc1ccc(CN2C(=O)/C(=C/c3ccccc3)/Sc4ccc(cc24)C(=O)N5CCCC5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O05 compound treatment 0.417 0.205 2.15 0.32 0.139 1.66 2.698 0.9919 3039672 ChemDiv3_014041 FC(F)(F)c1cccc(Nc2cc(C(=O)NCc3cccnc3)c4ccccc4n2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O06 compound treatment 0.458 0.246 2.58 0.396 0.215 2.57 3.6455 1.0 3120879 ChemDiv3_014042 CCOc1ccc(cc1)c2nc(CSCC(=O)N3CCOCC3)c(C)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O07 compound treatment 0.156 -0.0562 -0.59 0.148 -0.0329 -0.39 -0.6954 -0.9807 3039673 ChemDiv3_014043 COc1ccc(Nc2cc(C(=O)NCCC(C)C)c3ccccc3n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O08 compound treatment 0.282 0.0698 0.73 0.238 0.0571 0.68 1.0017 0.9994 3120880 ChemDiv3_014044 CC(C)CN(CC(C)C)C(=O)c1ccc2S/C(=C\c3ccccc3)/C(=O)Nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O09 compound treatment 0.261 0.0488 0.51 0.272 0.0911 1.09 1.1334 0.9409 3121069 ChemDiv3_014045 CC1CCCC(NC(=O)CC2Nc3ccccc3NC2=O)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O10 compound treatment 0.659 0.447 4.69 0.627 0.446 5.34 7.0925 0.9979 1418651 ChemDiv3_014046 COc1ccccc1NC(=O)c2c(NCc3cccs3)sc4CCCCCc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O11 compound treatment 0.104 -0.108 -1.14 0.106 -0.0749 -0.9 -1.4369 -0.9931 3039738 ChemDiv3_014047 CN(C1CCCCC1)C2CCN(CC2)C(=S)Nc3cc(F)cc(F)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O12 compound treatment 0.201 -0.0112 -0.12 0.189 0.00809 0.1 -0.0144 -0.0946 3039740 ChemDiv3_014048 O=C(CC1CC2CCC1C2)NC3CCCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O13 compound treatment 0.184 -0.0282 -0.3 0.17 -0.0109 -0.13 -0.3014 -0.9324 3039741 ChemDiv3_014049 Fc1ccccc1CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NC4CC4)/Oc5ccccc25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O14 compound treatment 0.699 0.487 5.11 0.657 0.476 5.7 7.6434 0.9985 3039743 ChemDiv3_014050 CCCNC(=O)c1ccc2ccccc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O15 compound treatment 0.091 -0.121 -1.27 0.08 -0.101 -1.21 -1.7534 -0.9997 3039744 ChemDiv3_014051 CCC(C)N(C)C1CCN(CC1)C(=S)Nc2cccc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O16 compound treatment 0.499 0.287 3.01 0.377 0.196 2.35 3.7892 0.9924 3039746 ChemDiv3_014052 CSc1ncccc1C(=O)NCc2ccccc2C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O17 compound treatment 0.253 0.0408 0.43 0.245 0.0641 0.77 0.8456 0.9623 3121070 ChemDiv3_014053 COc1ccccc1/C=C\2/Sc3ccc(cc3N(C)C2=O)C(=O)N4CCN(CC4)c5ncccn5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O18 compound treatment 0.303 0.0908 0.95 0.293 0.112 1.34 1.623 0.9861 3039748 ChemDiv3_014054 Cc1cc(NC(=O)Cc2cccc3ccccc23)n[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O19 compound treatment 0.177 -0.0352 -0.37 0.137 -0.0439 -0.53 -0.6325 -0.9851 3121071 ChemDiv3_014055 CC(C)NC(=S)N(CCc1ccncc1)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O20 compound treatment 0.313 0.101 1.06 0.283 0.102 1.22 1.6126 0.9975 3121072 ChemDiv3_014056 COc1ccc(C(=O)NCCc2ccc(O)cc2)c(OC)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O21 compound treatment 0.261 0.0488 0.51 0.181 9.38E-5 0.0 0.3635 0.7087 3039751 ChemDiv3_014057 Cc1ccsc1/C=C/C(=O)NCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O22 compound treatment 0.245 0.0328 0.34 0.234 0.0531 0.64 0.6931 0.9588 3121073 ChemDiv3_014058 COc1ccc(cc1)N2CCN(CC2)C(=O)CCCC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O23 mock treatment 0.167 -0.0452 -0.47 0.166 -0.0149 -0.18 -0.4615 -0.9107 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 O24 mock treatment 0.201 -0.0112 -0.12 0.156 -0.0249 -0.3 -0.2936 -0.9168 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P01 compound treatment 0.274 0.0618 0.65 0.258 0.0771 0.92 1.1115 0.9853 1113275 ChemDiv3_014059 O=C(CCC(=O)c1ccccc1)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P02 compound treatment 0.156 -0.0562 -0.59 0.131 -0.0499 -0.6 -0.8393 -1.0 1223469 ChemDiv3_014060 CCn1cnc2sc(C(=O)N(Cc3ccco3)Cc4ccc(cc4)N(C)C)c(C)c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P03 compound treatment 0.135 -0.0772 -0.81 0.127 -0.0539 -0.64 -1.0291 -0.9936 1132336 ChemDiv3_014061 COc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P04 compound treatment 0.115 -0.0972 -1.02 0.114 -0.0669 -0.8 -1.2876 -0.9928 1194685 ChemDiv3_014062 CCCn1c(=O)c(CC(=O)OCC)c(O)c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P05 compound treatment 0.469 0.257 2.7 0.367 0.186 2.23 3.4818 0.9955 3039754 ChemDiv3_014063 FC(F)(F)c1cccc(CNC(=O)c2cccs2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P06 compound treatment 0.15 -0.0622 -0.65 0.119 -0.0619 -0.74 -0.9853 -0.998 3121074 ChemDiv3_014064 CC(C)Cn1c(=O)c(C2=Nc3ccccc3S(=O)(=O)N2)c(O)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P07 compound treatment 0.268 0.0558 0.59 0.242 0.0611 0.73 0.9316 0.994 1400079 ChemDiv3_014065 CC(=O)Nc1c(OC(=O)C)ccc2c(C)cc(=O)oc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P08 compound treatment 0.269 0.0568 0.6 0.232 0.0511 0.61 0.8544 0.9999 1718046 ChemDiv3_014066 Oc1cccc(NC(=O)CCn2c(=S)oc3ccccc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P09 compound treatment 0.877 0.665 6.98 0.851 0.67 8.02 10.6066 0.9976 3039758 ChemDiv3_014067 COc1ccc2n(C)c3ccccc3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P10 compound treatment 0.298 0.0858 0.9 0.291 0.11 1.32 1.5689 0.9829 1122184 ChemDiv3_014068 COc1cccc(NC(=O)CNC(=O)Cn2cnc3sc4CCCCc4c3c2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P11 compound treatment 0.317 0.105 1.1 0.182 0.00109 0.01 0.7879 0.7155 3039818 ChemDiv3_014069 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)Nc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P12 compound treatment 0.276 0.0638 0.67 0.266 0.0851 1.02 1.194 0.9795 1425898 ChemDiv3_014070 CCOC(=O)c1ccccc1NC(=O)c2sc3nc(C)nc(N(CC)CC)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P13 compound treatment 0.264 0.0518 0.54 0.251 0.0701 0.84 0.978 0.9781 1266683 ChemDiv3_014071 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCOCC4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P14 compound treatment 0.198 -0.0142 -0.15 0.169 -0.0119 -0.14 -0.2059 -0.9998 1619997 ChemDiv3_014072 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P15 compound treatment 0.31 0.0978 1.03 0.263 0.0821 0.98 1.4212 0.9997 1580461 ChemDiv3_014073 COC(CNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCC(C)CC3)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P16 compound treatment 0.272 0.0598 0.63 0.256 0.0751 0.9 1.0797 0.9847 3121075 ChemDiv3_014074 CC1CC(C)CN(C1)C(=O)Cn2cnc3sc(C(=O)N(C)Cc4ccccc4)c(C)c3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P17 compound treatment 0.222 0.00984 0.1 0.181 9.38E-5 0.0 0.0739 0.7147 3121076 ChemDiv3_014075 CN(C)C(=O)C1=C(C)Nc2nc3ccccc3n2C1c4ccc(Br)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P18 compound treatment 0.194 -0.0182 -0.19 0.163 -0.0179 -0.21 -0.2863 -0.9983 1190662 ChemDiv3_014076 Cc1n[nH]c2nc(SCC(=O)NCCc3ccccc3)n(c4ccccc4Cl)c(=N)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P19 compound treatment 0.269 0.0568 0.6 0.188 0.00709 0.08 0.4822 0.7996 1542072 ChemDiv3_014077 CC1=C(C(C2=C(CCCC2=O)N1)c3cccs3)C(=O)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P20 compound treatment 0.158 -0.0542 -0.57 0.168 -0.0129 -0.15 -0.5114 -0.8677 3039823 ChemDiv3_014078 CSCCC1N2C(=S)NC(C)(C)CC2(C)N(N)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P21 compound treatment 1.002 0.79 8.3 1.006 0.825 9.87 12.8462 0.9963 3121077 ChemDiv3_014079 CCOC(=O)C1=CN(C=C(C1c2ccccc2Br)C(=O)OCC)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P22 compound treatment 0.161 -0.0512 -0.54 0.168 -0.0129 -0.15 -0.4891 -0.8749 3039825 ChemDiv3_014080 CC(=O)Nc1nc(cs1)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P23 mock treatment 0.174 -0.0382 -0.4 0.172 -0.00891 -0.11 -0.3587 -0.8651 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2040 P24 mock treatment 0.203 -0.00916 -0.1 0.165 -0.0159 -0.19 -0.2026 -0.95 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A01 compound treatment 0.341 0.146 1.54 0.34 0.0579 0.69 1.5767 0.9353 3121078 ChemDiv3_014081 CCOc1ccc2nc(sc2c1)C(=O)N3CCCC(C)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A02 compound treatment 0.221 0.0263 0.28 0.258 -0.0241 -0.29 -0.0082 -0.0205 1329091 ChemDiv3_014082 COc1ccc(cc1)C2=NC(NC(C2)c3ccccc3O)c4ccccc4OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A03 compound treatment 0.277 0.0823 0.86 0.341 0.0589 0.71 1.1099 0.9949 3039828 ChemDiv3_014083 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCN(CC3)c4cc(Cl)ccc4C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A04 compound treatment 0.342 0.147 1.55 0.411 0.129 1.54 2.1848 1.0 1633854 ChemDiv3_014084 CCOc1ccc(cc1)N(C)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCC4CCCO4)c(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A05 compound treatment 0.983 0.788 8.28 1.23 0.948 11.34 13.8741 0.988 3121079 ChemDiv3_014085 CCOC(=O)c1cc(c2ccccc2)n(c1C)c3cccc(c3)C(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A06 compound treatment 0.261 0.0663 0.7 0.305 0.0229 0.27 0.6865 0.9171 1351188 ChemDiv3_014086 COC(CNC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A07 compound treatment 0.298 0.103 1.09 0.381 0.0989 1.18 1.6043 0.9991 3121080 ChemDiv3_014087 Cc1noc(/C=C/c2ccco2)c1S(=O)(=O)N3CCC(CC3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A08 compound treatment 0.25 0.0553 0.58 0.29 0.00794 0.09 0.4779 0.8119 3039830 ChemDiv3_014088 Brc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A09 compound treatment 0.295 0.1 1.05 0.394 0.112 1.34 1.692 0.9929 3121081 ChemDiv3_014089 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3c(C)noc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A10 compound treatment 0.221 0.0263 0.28 0.326 0.0439 0.53 0.5671 0.9549 3039832 ChemDiv3_014090 CC(C)OC(=O)CN1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A11 compound treatment 0.294 0.0993 1.04 0.361 0.0789 0.94 1.4054 0.9988 1112897 ChemDiv3_014091 Cc1ccc(cc1)c2cc3ccccn3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A12 compound treatment 0.25 0.0553 0.58 0.329 0.0469 0.56 0.8079 0.9999 3121082 ChemDiv3_014092 CC(NC(=O)CCn1c(=S)oc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A13 compound treatment 0.223 0.0283 0.3 0.275 -0.00706 -0.08 0.1505 0.4869 3039835 ChemDiv3_014093 CC1CCC(CC1)NC(=O)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A14 compound treatment 0.29 0.0953 1.0 0.39 0.108 1.29 1.621 0.9921 3039892 ChemDiv3_014094 Brc1ccc(cc1)S(=O)(=O)CCC(=O)N2CCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A15 compound treatment 0.297 0.102 1.07 0.394 0.112 1.34 1.7068 0.994 3039893 ChemDiv3_014095 CN(C)/C=C/c1onc(C)c1S(=O)(=O)N(C)CCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A16 compound treatment 0.226 0.0313 0.33 0.306 0.0239 0.29 0.4351 0.9976 1322055 ChemDiv3_014096 Nc1ccc(cc1)N2CCNCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A17 compound treatment 0.217 0.0223 0.23 0.313 0.0309 0.37 0.4274 0.9757 3039895 ChemDiv3_014097 CC(C)NS(=O)(=O)c1c(C)noc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A18 compound treatment 0.05 -0.145 -1.52 0.049 -0.233 -2.79 -3.0463 -0.9593 1643280 ChemDiv3_014098 Nc1ccc(Oc2ccc3ccccc3c2Cl)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A19 compound treatment 0.174 -0.0207 -0.22 0.269 -0.0131 -0.16 -0.2641 -0.9869 3039897 ChemDiv3_014099 CNC(=O)C1CCN(CC1)S(=O)(=O)c2c(C)noc2/C=C/N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A20 compound treatment 0.573 0.378 3.97 0.665 0.383 4.58 6.0492 0.9975 1143154 ChemDiv3_014100 OC(=O)c1ccc2C(=O)N(CCC3=CCCCC3)C(=O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A21 compound treatment 0.253 0.0583 0.61 0.322 0.0399 0.48 0.7709 0.9925 3039899 ChemDiv3_014101 COc1ccccc1CC(=O)Nc2ccc(cc2)c3noc(COc4ccc(Cl)c(C)c4)n3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A22 compound treatment 0.251 0.0563 0.59 0.355 0.0729 0.87 1.0353 0.982 3039901 ChemDiv3_014102 Cc1ccc(cc1)c2c(oc(=O)c3ccccc23)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A23 mock treatment 0.194 -6.88E-4 -0.01 0.279 -0.00306 -0.04 -0.031 -0.8305 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 A24 mock treatment 0.211 0.0163 0.17 0.28 -0.00206 -0.02 0.1037 0.5991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B01 compound treatment 0.299 0.104 1.1 0.321 0.0389 0.47 1.1041 0.9274 3121083 ChemDiv3_014103 COc1ccc(cc1)c2n[nH]cc2C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B02 compound treatment 0.257 0.0623 0.65 0.368 0.0859 1.03 1.1898 0.9762 3121084 ChemDiv3_014104 CC(C)C1=NC(NN1c2ccccc2)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B03 compound treatment 0.338 0.143 1.51 0.404 0.122 1.46 2.0959 0.9999 1037837 ChemDiv3_014105 Nc1ccc(OCc2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B04 compound treatment 0.265 0.0703 0.74 0.303 0.0209 0.25 0.6993 0.8968 3121085 ChemDiv3_014106 CC(N1C(=O)NC(C2=C1CC(C)(C)CC2=O)(C(F)(F)F)C(F)(F)F)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B05 compound treatment 0.113 -0.0817 -0.86 0.108 -0.174 -2.08 -2.0792 -0.9231 3039905 ChemDiv3_014107 OC(=O)Cc1ccc(NCc2ccc(Br)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B06 compound treatment 0.306 0.111 1.17 0.441 0.159 1.9 2.1713 0.9727 3039906 ChemDiv3_014108 O=c1[nH]c(=O)c2[nH]cnc2n1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B07 compound treatment 0.225 0.0303 0.32 0.307 0.0249 0.3 0.4361 0.9995 3121086 ChemDiv3_014109 OC(=O)CCSCc1ccccc1F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B08 compound treatment 0.203 0.00831 0.09 0.291 0.00894 0.11 0.1373 0.9949 3121087 ChemDiv3_014110 Nc1cc(=O)n2C(CS(=O)(=O)c3ccccc3)CSc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B09 compound treatment 0.197 0.00231 0.02 0.347 0.0649 0.78 0.5666 0.7289 3039909 ChemDiv3_014111 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B10 compound treatment 0.277 0.0823 0.86 0.398 0.116 1.39 1.5921 0.9741 3121088 ChemDiv3_014112 CCCc1cc(=O)c2c(=O)n([nH]c2[nH]1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B11 compound treatment 0.144 -0.0507 -0.53 0.189 -0.0931 -1.11 -1.1638 -0.943 1619398 ChemDiv3_014113 COc1ccccc1n2c(C)nc3cc(ccc23)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B12 compound treatment 0.265 0.0703 0.74 0.355 0.0729 0.87 1.1392 0.9965 3121089 ChemDiv3_014114 NC1=NC(N2C(=N1)Sc3ccccc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B13 compound treatment 0.111 -0.0837 -0.88 0.148 -0.134 -1.6 -1.7557 -0.9599 3039912 ChemDiv3_014115 CCn1c2ccccc2c3nn(C)c(=N)nc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B14 compound treatment 0.416 0.221 2.32 0.518 0.236 2.82 3.6396 0.9953 3121090 ChemDiv3_014116 C=CCNc1nc2c([nH]c3ccccc23)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B15 compound treatment 0.202 0.00731 0.08 0.309 0.0269 0.32 0.2822 0.8518 3039968 ChemDiv3_014117 CN(Cc1ccccc1)S(=O)(=O)c2ccc3n(C)c(=O)n(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B16 compound treatment 0.188 -0.00669 -0.07 0.275 -0.00706 -0.08 -0.1094 -0.9958 3039970 ChemDiv3_014118 NC1=C(C#N)C(c2ccncc2)c3c(O)ncnc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B17 compound treatment 0.143 -0.0517 -0.54 0.188 -0.0941 -1.13 -1.1796 -0.9441 3039971 ChemDiv3_014119 OC(=O)c1ccc(cc1)C2NC(=O)C(=C(SCc3ccccc3)S2)C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B18 compound treatment 0.182 -0.0127 -0.13 0.255 -0.0271 -0.32 -0.3232 -0.923 3039972 ChemDiv3_014120 COC(=O)c1ccc2c(=O)n3nc(N)sc3nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B19 compound treatment 0.325 0.13 1.37 0.447 0.165 1.97 2.3632 0.984 3039974 ChemDiv3_014121 O=c1[nH]c(CSc2nc3ccccc3o2)nc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B20 compound treatment 0.129 -0.0657 -0.69 0.163 -0.119 -1.42 -1.4951 -0.9446 3039976 ChemDiv3_014122 CCCCN1COc2ccc3c(C)cc(=O)oc3c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B21 compound treatment 0.236 0.0413 0.43 0.34 0.0579 0.69 0.797 0.9745 3039977 ChemDiv3_014123 CC1CC(=O)C2=C(C1)Nc3nc4ccccc4n3C2c5cccs5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B22 compound treatment 0.182 -0.0127 -0.13 0.229 -0.0531 -0.63 -0.5431 -0.8373 3039979 ChemDiv3_014124 NC1=NC(N(CCc2ccc(F)cc2)C(=N1)N)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B23 mock treatment 0.212 0.0173 0.18 0.329 0.0469 0.56 0.5257 0.8905 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 B24 mock treatment 0.189 -0.00569 -0.06 0.265 -0.0171 -0.2 -0.1866 -0.8772 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C01 compound treatment 0.243 0.0483 0.51 0.262 -0.0201 -0.24 0.1891 0.3368 3121091 ChemDiv3_014125 CC(C)c1ccc(cc1)n2cccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C02 compound treatment 0.235 0.0403 0.42 0.261 -0.0211 -0.25 0.1212 0.246 1717842 ChemDiv3_014126 CCOc1ccc(cc1)C2=NC(NC(C2)c3ccccc3O)c4ccc(OC)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C03 compound treatment 0.73 0.535 5.62 0.794 0.512 6.13 8.3066 0.9991 3039981 ChemDiv3_014127 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCc4ccccc34)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C04 compound treatment 0.331 0.136 1.43 0.38 0.0979 1.17 1.8409 0.9951 1387961 ChemDiv3_014128 COC(CNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N(C)c3ccc(cc3)C(C)C)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C05 compound treatment 0.231 0.0363 0.38 0.35 0.0679 0.81 0.8444 0.9405 3121277 ChemDiv3_014129 O=C(NC1CCCC1)C2CCCN(C2)S(=O)(=O)c3cccc4cccnc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C06 compound treatment 0.258 0.0633 0.66 0.341 0.0589 0.71 0.9688 0.9996 1469378 ChemDiv3_014130 COc1ccc(cc1)S(=O)(=O)NC(CC(=O)N2CCC3(CC2)OCCO3)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C07 compound treatment 0.247 0.0523 0.55 0.393 0.111 1.33 1.327 0.9238 3121278 ChemDiv3_014131 O=C1Cc2cc(ccc2N1)S(=O)(=O)NCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C08 compound treatment 0.199 0.00431 0.05 0.337 0.0549 0.66 0.4968 0.754 3039984 ChemDiv3_014132 CCOc1ccccc1NC(=O)CCN2CCN(CC2)S(=O)(=O)c3ccc(Br)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C09 compound treatment 0.18 -0.0147 -0.15 0.313 0.0309 0.37 0.1527 0.3807 1032549 ChemDiv3_014133 CCOC(=O)C1CCCCN1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C10 compound treatment 0.216 0.0213 0.22 0.401 0.119 1.42 1.1645 0.8084 1171382 ChemDiv3_014134 CC(C)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C11 compound treatment 0.167 -0.0277 -0.29 0.339 0.0569 0.68 0.2761 0.3727 3039986 ChemDiv3_014135 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C12 compound treatment 0.273 0.0783 0.82 0.434 0.152 1.82 1.867 0.9357 1318029 ChemDiv3_014136 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)N4CCC(=CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C13 compound treatment 0.514 0.319 3.35 0.55 0.268 3.21 4.6382 0.9997 3121279 ChemDiv3_014137 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)N3CCc4ccccc4C3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C14 compound treatment 0.236 0.0413 0.43 0.34 0.0579 0.69 0.797 0.9745 3039989 ChemDiv3_014138 Brc1ccc(cc1)S(=O)(=O)CCC(=O)N2CC(=O)N(CCc3ccccc3)C(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C15 compound treatment 0.05 -0.145 -1.52 0.047 -0.235 -2.81 -3.0632 -0.9582 3121280 ChemDiv3_014139 CC(C)c1ccc(cc1)N(C)S(=O)(=O)c2c(C)noc2/C=C/N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C16 compound treatment 0.184 -0.0107 -0.11 0.332 0.0499 0.6 0.3431 0.5644 1627807 ChemDiv3_014140 OC(=O)c1ccc2ncccc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C17 compound treatment 0.176 -0.0187 -0.2 0.265 -0.0171 -0.2 -0.2831 -0.9998 3121281 ChemDiv3_014141 O=C(Cn1cnc(c1)S(=O)(=O)N2CCCC2)NC3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C18 compound treatment 0.198 0.00331 0.03 0.313 0.0309 0.37 0.2863 0.7702 3038771 ChemDiv3_014142 Cc1cc(nn1CC(=O)O)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C19 compound treatment 0.273 0.0783 0.82 0.303 0.0209 0.25 0.7587 0.8824 3038773 ChemDiv3_014143 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCSc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C20 compound treatment 0.239 0.0443 0.47 0.377 0.0949 1.14 1.1323 0.9224 1727323 ChemDiv3_014144 O=C(Nc1ccccc1)c2ccc3C(=O)N(CCC4=CCCCC4)C(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C21 compound treatment 0.211 0.0163 0.17 0.274 -0.00806 -0.1 0.0529 0.2692 3038774 ChemDiv3_014145 CCOC(=O)C1C(/C=C/c2ccccc2)C(C(=O)OCC)C(C)(O)CC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C22 compound treatment 0.236 0.0413 0.43 0.352 0.0699 0.84 0.8985 0.9532 3038776 ChemDiv3_014146 CC1CCc2[nH]nc(C(=O)O)c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C23 mock treatment 0.183 -0.0117 -0.12 0.274 -0.00806 -0.1 -0.155 -0.9929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 C24 mock treatment 0.2 0.00531 0.06 0.295 0.0129 0.15 0.1489 0.905 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D01 compound treatment 0.46 0.265 2.79 0.559 0.277 3.31 4.3133 0.9963 3038777 ChemDiv3_014147 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)O)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D02 compound treatment 0.369 0.174 1.83 0.342 0.0599 0.72 1.8016 0.9163 3038779 ChemDiv3_014148 CC1=NN(C(=O)C21C3CC(C=C3)C2(C(F)(F)F)C(F)(F)F)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D03 compound treatment 0.277 0.0823 0.86 0.307 0.0249 0.3 0.8223 0.8991 1041548 ChemDiv3_014149 CC(C)(C)c1cc(O)cc(c1)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D04 compound treatment 0.194 -6.88E-4 -0.01 0.323 0.0409 0.49 0.3412 0.6966 3038781 ChemDiv3_014150 C(Nc1nc[n+]2CCn3cnc1c32)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D05 compound treatment 0.053 -0.142 -1.49 0.059 -0.223 -2.67 -2.9394 -0.9619 3121282 ChemDiv3_014151 OC(=O)c1ccccc1NCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D06 compound treatment 0.145 -0.0497 -0.52 0.152 -0.13 -1.56 -1.4694 -0.8952 3121283 ChemDiv3_014152 C=CCn1cnc2c(NCc3ccccc3)ncnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D07 compound treatment 0.087 -0.108 -1.13 0.097 -0.185 -2.21 -2.3654 -0.9514 3038783 ChemDiv3_014153 COc1ccc(CN2CC(CC2=O)C(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D08 compound treatment 0.845 0.65 6.83 1.017 0.735 8.79 11.0472 0.9922 3121284 ChemDiv3_014154 Nc1ccccc1SC2=CS(=O)(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D09 compound treatment 0.129 -0.0657 -0.69 0.158 -0.124 -1.48 -1.5374 -0.9393 3038785 ChemDiv3_014155 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D10 compound treatment 0.216 0.0213 0.22 0.394 0.112 1.34 1.1053 0.814 3121285 ChemDiv3_014156 COc1ccc(cc1)c2nc(C=C3C(=O)c4ccccc4C3=O)c5ccccn25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D11 compound treatment 0.187 -0.00769 -0.08 0.375 0.0929 1.11 0.7292 0.654 3038787 ChemDiv3_014157 COc1ccc2[nH]c(=O)c(cc2c1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D12 compound treatment 0.136 -0.0587 -0.62 0.431 0.149 1.78 0.8242 0.4371 3121286 ChemDiv3_014158 Cc1[nH]c2ccccc2c1C3(O)C(=O)N(Cc4ccc(C)cc4)c5ccc(Br)cc53 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D13 compound treatment 1.352 1.16 12.15 1.446 1.16 13.93 18.4419 0.9977 3038789 ChemDiv3_014159 Cc1nc(N)c(C#N)c(c2ccc(Br)s2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D14 compound treatment 0.318 0.123 1.3 0.625 0.343 4.1 3.8171 0.8872 3121287 ChemDiv3_014160 CC(=O)n1c2sc(N3CCOCC3)c(c4ccccc4)c2c5ccccc15 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D15 compound treatment 0.134 -0.0607 -0.64 0.221 -0.0611 -0.73 -0.9673 -0.9977 3121288 ChemDiv3_014161 CC1CCc2c(C1)sc3ncnc(SCC(=O)Nc4nsc(n4)c5ccccc5C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D16 compound treatment 0.201 0.00631 0.07 0.322 0.0399 0.48 0.3848 0.7976 3038791 ChemDiv3_014162 COC(=O)C1=C(N)Oc2c(oc(CO)cc2=O)C1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D17 compound treatment 0.215 0.0203 0.21 0.292 0.00994 0.12 0.2349 0.9619 3038792 ChemDiv3_014163 CC(C)(C)N1CC(CC1=O)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D18 compound treatment 0.127 -0.0677 -0.71 0.161 -0.121 -1.45 -1.5269 -0.9463 3121289 ChemDiv3_014164 OC(=O)CCc1nn2c(=O)c3ccccc3nc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D19 compound treatment 1.187 0.992 10.42 1.269 0.987 11.81 15.719 0.9981 3038794 ChemDiv3_014165 COc1ccc2CCc3sc(C)nc3-c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D20 compound treatment 0.227 0.0323 0.34 0.32 0.0379 0.45 0.5609 0.9897 3121290 ChemDiv3_014166 Cc1ccc(cc1)c2n[nH]c3nc(cc(c4cccc5ccccc45)c23)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D21 compound treatment 0.193 -0.00169 -0.02 0.303 0.0209 0.25 0.1646 0.6554 3038796 ChemDiv3_014167 CC1=NC(N=C(O1)N2CCCCC2)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D22 compound treatment 0.152 -0.0427 -0.45 0.302 0.0199 0.24 -0.1483 -0.2921 3121291 ChemDiv3_014168 Nc1cnn(c2ccccc2)c(=O)c1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D23 mock treatment 0.21 0.0153 0.16 0.309 0.0269 0.32 0.3416 0.9484 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 D24 mock treatment 0.183 -0.0117 -0.12 0.283 9.37E-4 0.01 -0.0789 -0.6398 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E01 compound treatment 0.272 0.0773 0.81 0.25 -0.0321 -0.38 0.3029 0.3373 3121292 ChemDiv3_014169 CC1Cc2ccccc2N1C(=O)CSCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E02 compound treatment 0.185 -0.00969 -0.1 0.249 -0.0331 -0.4 -0.3517 -0.861 3038858 ChemDiv3_014170 Oc1ccccc1C2CC(=NC(N2)c3ccc(Br)cc3)c4cccc(Br)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E03 compound treatment 0.367 0.172 1.81 0.474 0.192 2.3 2.9035 0.993 3038859 ChemDiv3_014171 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCCCCC3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E04 compound treatment 0.226 0.0313 0.33 0.313 0.0309 0.37 0.4943 0.9983 3038861 ChemDiv3_014172 CCCNC(=O)Cn1cnc2sc(C(=O)NCCCN3CCOCC3)c(C)c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E05 compound treatment 0.182 -0.0127 -0.13 0.345 0.0629 0.75 0.4382 0.5731 3038862 ChemDiv3_014173 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCCC3C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E06 compound treatment 0.256 0.0613 0.64 0.384 0.102 1.22 1.3177 0.9555 1313876 ChemDiv3_014174 COc1ccc(cc1)C(CC(=O)NC2CCCC2)NS(=O)(=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E07 compound treatment 0.237 0.0423 0.44 0.359 0.0769 0.92 0.9651 0.9442 3038865 ChemDiv3_014175 O=C1Cc2cc(ccc2N1)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E08 compound treatment 0.349 0.154 1.62 0.532 0.25 2.99 3.2605 0.9586 3121293 ChemDiv3_014176 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)/C=C/c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E09 compound treatment 0.207 0.0123 0.13 0.392 0.11 1.32 1.0215 0.7729 3038867 ChemDiv3_014177 CN(CC(=O)NC1CCCC1)S(=O)(=O)c2ccc3nc(C)sc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E10 compound treatment 0.22 0.0253 0.27 0.409 0.127 1.52 1.2619 0.8184 3121294 ChemDiv3_014178 COc1ccc(cc1)C(=O)N2CCN(CC2)S(=O)(=O)c3cc(Cl)ccc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E11 compound treatment 0.157 -0.0377 -0.4 0.31 0.0279 0.33 -0.0435 -0.084 3038869 ChemDiv3_014179 Cn1cnc(c1)S(=O)(=O)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E12 compound treatment 0.221 0.0263 0.28 0.379 0.0969 1.16 1.0155 0.8517 1381314 ChemDiv3_014180 Cc1cccc(NC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E13 compound treatment 0.268 0.0733 0.77 0.432 0.15 1.79 1.8129 0.9287 3121295 ChemDiv3_014181 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)NC3CCCC(C)C3C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E14 compound treatment 0.205 0.0103 0.11 0.387 0.105 1.26 0.9644 0.7653 3038872 ChemDiv3_014182 COc1ccc(cc1)S(=O)(=O)CCC(=O)Nc2ccc(OC(F)(F)F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E15 compound treatment 0.288 0.0933 0.98 0.475 0.193 2.31 2.3253 0.9272 3121296 ChemDiv3_014183 Cc1noc(/C=C/N2CCOCC2)c1S(=O)(=O)N3CCN(CC3)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E16 compound treatment 0.292 0.0973 1.02 0.535 0.253 3.03 2.8626 0.8962 3038873 ChemDiv3_014184 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(Br)cc2C(NCC(=O)O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E17 compound treatment 0.177 -0.0177 -0.19 0.388 0.106 1.27 0.7649 0.5971 3121297 ChemDiv3_014185 CN(CC(=O)NCc1ccccc1)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E18 compound treatment 0.117 -0.0777 -0.82 0.148 -0.134 -1.6 -1.7111 -0.9509 1043920 ChemDiv3_014186 NC(=O)C1(CCN(Cc2ccccc2)CC1)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E19 compound treatment 0.381 0.186 1.96 0.488 0.206 2.46 3.1259 0.9935 3038876 ChemDiv3_014187 Cc1cc(C)cc(NS(=O)(=O)c2ccc3N(CCOc3c2)C(=O)c4ccco4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E20 compound treatment 0.216 0.0213 0.22 0.387 0.105 1.26 1.0461 0.8202 1431633 ChemDiv3_014188 COc1ccc(cc1)N2CCN(CC2)c3ccc(NC(=O)c4ccc(OC)cc4)cc3C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E21 compound treatment 0.94 0.745 7.83 1.035 0.753 9.01 11.905 0.9975 1147292 ChemDiv3_014189 COc1ccccc1CNC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccc5F)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E22 compound treatment 0.178 -0.0167 -0.18 0.318 0.0359 0.43 0.1801 0.3879 3038879 ChemDiv3_014190 CC(CN1CCCCC1)C(=O)NN 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E23 mock treatment 0.198 0.00331 0.03 0.3 0.0179 0.21 0.1764 0.8111 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 E24 mock treatment 0.19 -0.00469 -0.05 0.271 -0.0111 -0.13 -0.1284 -0.9093 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F01 compound treatment 0.568 0.373 3.92 0.599 0.317 3.79 5.4537 0.9999 3038881 ChemDiv3_014191 Cc1c(cc(c2ccccc2)n1Cc3ccccc3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F02 compound treatment 0.315 0.12 1.26 0.417 0.135 1.61 2.0351 0.9927 3038929 ChemDiv3_014192 FC(F)(F)C1(N=C(N2C=CC=CC2=N1)c3ccccc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F03 compound treatment 0.227 0.0323 0.34 0.323 0.0409 0.49 0.5863 0.9839 1013222 ChemDiv3_014193 CCN(CC)c1ccc(cc1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F04 compound treatment 0.181 -0.0137 -0.14 0.296 0.0139 0.17 0.0163 0.0739 3121473 ChemDiv3_014194 Nc1ncnc2n(CCNCc3ccccc3)cnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F05 compound treatment 0.152 -0.0427 -0.45 0.178 -0.104 -1.25 -1.1974 -0.9049 3038931 ChemDiv3_014195 OC(=O)c1ccc2n(cnc2c1)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F06 compound treatment 0.889 0.694 7.29 1.05 0.768 9.19 11.6532 0.9934 3121474 ChemDiv3_014196 COc1ccc(cc1OC)C(=O)OCC2CC(=NO2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F07 compound treatment 0.255 0.0603 0.63 0.361 0.0789 0.94 1.1157 0.9811 3038933 ChemDiv3_014197 NNC(=O)c1ccc(CN2CCCCC2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F08 compound treatment 0.047 -0.148 -1.55 0.124 -0.158 -1.89 -2.434 -0.9952 3038995 ChemDiv3_014198 Cc1ccc(C(=O)O)c2C3C=CCC3[C@H](Nc12)c4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F09 compound treatment 0.202 0.00731 0.08 0.382 0.0999 1.2 0.8998 0.751 3038997 ChemDiv3_014199 Cc1c(oc2ccc(cc12)S(=O)(=O)N3CCCC3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F10 compound treatment 0.108 -0.0867 -0.91 0.101 -0.181 -2.17 -2.1756 -0.9258 3038998 ChemDiv3_014200 C(N1CN(Cc2ccccc2)c3nc4ccccc4n3C1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F11 compound treatment 0.309 0.114 1.2 0.485 0.203 2.43 2.5658 0.9473 1739322 ChemDiv3_014201 CC(C)(C)c1cc(CCC(=O)NN)cc(c1O)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F12 compound treatment 0.109 -0.0857 -0.9 0.18 -0.102 -1.22 -1.4998 -0.9887 3039000 ChemDiv3_014202 CC(C)(C)NC1C=C(Sc2nc(cn12)c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F13 compound treatment 0.29 0.0953 1.0 0.461 0.179 2.14 2.2217 0.94 3039002 ChemDiv3_014203 Nc1nc2CCCCc2c(c3ccc(Br)s3)c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F14 compound treatment 0.231 0.0363 0.38 0.322 0.0399 0.48 0.6076 0.9938 1598994 ChemDiv3_014204 CC(=O)n1c2sc(N3CCCCC3)c(C#N)c2c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F15 compound treatment 0.311 0.116 1.22 0.619 0.337 4.03 3.7143 0.8818 3039004 ChemDiv3_014205 CCOc1ccc2nc(SCC(=O)N3CCN(C3)C(=O)c4ccc(C)cc4)sc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F16 compound treatment 0.168 -0.0267 -0.28 0.353 0.0709 0.85 0.4019 0.4497 3121475 ChemDiv3_014206 CCNc1nc2[nH]c(=O)c3C(C(=C(N)Oc3c2s1)C#N)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F17 compound treatment 0.466 0.271 2.85 0.732 0.45 5.38 5.8214 0.9558 3039006 ChemDiv3_014207 C(Sc1nn2cnnc2s1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F18 compound treatment 0.113 -0.0817 -0.86 0.148 -0.134 -1.6 -1.7408 -0.957 3039007 ChemDiv3_014208 Nn1c(=O)c2ccc(cc2[nH]c1=S)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F19 compound treatment 0.37 0.175 1.84 0.588 0.306 3.66 3.8902 0.9494 3121476 ChemDiv3_014209 COc1ccc(cc1)c2cc(n3nc(N)nc3n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F20 compound treatment 0.512 0.317 3.33 0.659 0.377 4.51 5.5455 0.9889 3121477 ChemDiv3_014210 CC1=C(C(c2ccccc2)n3ncc(C(=O)Nc4ccccc4)c3N1)C(=O)Nc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F21 compound treatment 0.281 0.0863 0.91 0.409 0.127 1.52 1.7149 0.9696 3039010 ChemDiv3_014211 Cc1nn(c2OC(=NC(c12)(C(F)(F)F)C(F)(F)F)N3CCOCC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F22 compound treatment 0.186 -0.00869 -0.09 0.301 0.0189 0.23 0.0957 0.3918 3121478 ChemDiv3_014212 COc1ccc(Cl)cc1S(=O)(=O)Nc2ccc3C(=O)OCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F23 mock treatment 0.181 -0.0137 -0.14 0.303 0.0209 0.25 0.0755 0.2614 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 F24 mock treatment 0.202 0.00731 0.08 0.268 -0.0141 -0.17 -0.0647 -0.3496 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G01 compound treatment 0.603 0.408 4.29 0.588 0.306 3.66 5.6206 0.9969 3039012 ChemDiv3_014213 O=C(Cc1ccc(cc1)n2cccc2)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G02 compound treatment 0.184 -0.0107 -0.11 0.238 -0.0441 -0.53 -0.4521 -0.8389 1714096 ChemDiv3_014214 COc1cccc(c1)C2=NC(C)(C)NC(C2)c3ccccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G03 compound treatment 0.655 0.46 4.83 0.719 0.437 5.23 7.1151 0.9992 3121479 ChemDiv3_014215 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)Nc3nc4ccc(Cl)cc4s3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G04 compound treatment 0.251 0.0563 0.59 0.387 0.105 1.26 1.306 0.941 1714352 ChemDiv3_014216 CCCNC(=O)Cn1cnc2sc(C(=O)N3CCC(Cc4ccccc4)CC3)c(C)c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G05 compound treatment 0.329 0.134 1.41 0.481 0.199 2.38 2.6805 0.9688 3121480 ChemDiv3_014217 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)N3CCCCCC3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G06 compound treatment 0.218 0.0233 0.24 0.347 0.0649 0.78 0.7225 0.8869 1220187 ChemDiv3_014218 COc1ccc(cc1)S(=O)(=O)NC(CC(=O)N2CCCCC2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G07 compound treatment 0.354 0.159 1.67 0.47 0.188 2.25 2.7731 0.9894 3038882 ChemDiv3_014219 CN(C)/C=C/c1onc(C)c1S(=O)(=O)N(C)Cc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G08 compound treatment 0.149 -0.0457 -0.48 0.207 -0.0751 -0.9 -0.9743 -0.9569 1710074 ChemDiv3_014220 Cc1ccccc1CN2CCN(CC2)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G09 compound treatment 0.182 -0.0127 -0.13 0.342 0.0599 0.72 0.4129 0.566 3038935 ChemDiv3_014221 CN(C)/C=C/c1onc(C)c1S(=O)(=O)NC2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G10 compound treatment 0.894 0.699 7.34 1.049 0.767 9.18 11.6818 0.9939 1284663 ChemDiv3_014222 CC(C)NC(=O)c1oc(=O)c2ccccc2c1c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G11 compound treatment 0.249 0.0543 0.57 0.449 0.167 2.0 1.8157 0.8741 3038937 ChemDiv3_014223 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G12 compound treatment 0.184 -0.0107 -0.11 0.226 -0.0561 -0.67 -0.5537 -0.8141 1285233 ChemDiv3_014224 CC1CCCC(C)N1C(=O)CCN2C(=O)C3C4CC(C=C4)C3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G13 compound treatment 0.223 0.0283 0.3 0.256 -0.0261 -0.31 -0.0102 -0.0237 3038939 ChemDiv3_014225 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)N(C)Cc3ccccc3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G14 compound treatment 0.239 0.0443 0.47 0.416 0.134 1.6 1.4622 0.8763 3038941 ChemDiv3_014226 COc1ccc(cc1)S(=O)(=O)CCC(=O)N(C)c2ccc(OC)cc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G15 compound treatment 0.425 0.23 2.42 0.617 0.335 4.01 4.544 0.9708 3038942 ChemDiv3_014227 CCc1ccccc1N(C)S(=O)(=O)c2c(C)noc2/C=C/N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G16 compound treatment 0.727 0.532 5.59 0.71 0.428 5.12 7.5736 0.999 1609499 ChemDiv3_014228 O=C(c1ccccc1)c2ccc3CCc4cccc2c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G17 compound treatment 0.256 0.0613 0.64 0.408 0.126 1.51 1.5208 0.9281 3121481 ChemDiv3_014229 COc1ccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)NCc4ccccc4)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G18 compound treatment 0.282 0.0873 0.92 0.527 0.245 2.93 2.7206 0.886 3038944 ChemDiv3_014230 OC(=O)c1cc(cc2ccccc12)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G19 compound treatment 0.183 -0.0117 -0.12 0.308 0.0259 0.31 0.1326 0.3974 3121482 ChemDiv3_014231 O=C(N1NC2(CCCC2)NC1=O)c3ccncc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G20 compound treatment 0.141 -0.0537 -0.56 0.215 -0.0671 -0.8 -0.9661 -0.9851 1570307 ChemDiv3_014232 CCN1CCc2c(C(=O)OC)c(N)sc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G21 compound treatment 0.463 0.268 2.82 0.658 0.376 4.5 5.1731 0.9746 1516404 ChemDiv3_014233 CN(Cc1ccccc1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccc5)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G22 compound treatment 0.109 -0.0857 -0.9 0.153 -0.129 -1.54 -1.7282 -0.967 1147592 ChemDiv3_014234 CCOC(=O)CC(N)c1ccc(C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G23 mock treatment 0.16 -0.0347 -0.36 0.305 0.0229 0.27 -0.0636 -0.1393 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 G24 mock treatment 0.183 -0.0117 -0.12 0.276 -0.00606 -0.07 -0.1381 -0.9685 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H01 compound treatment 0.258 0.0633 0.66 0.269 -0.0131 -0.16 0.3597 0.5266 1184652 ChemDiv3_014235 Cc1ccc(cc1C)S(=O)(=O)CCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H02 compound treatment 0.572 0.377 3.96 0.676 0.394 4.71 6.1349 0.9963 3121483 ChemDiv3_014236 CCOc1ccc2N3C(=NC(NC3=O)(C(F)(F)F)C(F)(F)F)Sc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H03 compound treatment 0.066 -0.129 -1.35 0.074 -0.208 -2.49 -2.7159 -0.9588 3038948 ChemDiv3_014237 OC(=O)/C=C/c1ccc(Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H04 compound treatment 0.466 0.271 2.85 0.648 0.366 4.38 5.1108 0.9784 3121484 ChemDiv3_014238 COc1ccccc1C2=NOC(COC(=O)c3ccc4ccccc4n3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H05 compound treatment 0.2 0.00531 0.06 0.381 0.0989 1.18 0.8765 0.7396 1238998 ChemDiv3_014239 OC(=O)C1CCC(CNCc2ccncc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H06 compound treatment 0.657 0.462 4.86 0.801 0.519 6.21 7.8237 0.9926 3121485 ChemDiv3_014240 CSc1nsc(SCC(=O)N2CCCc3ccccc23)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H07 compound treatment 0.113 -0.0817 -0.86 0.134 -0.148 -1.77 -1.8593 -0.9446 3038951 ChemDiv3_014241 Cc1ccc(CSCCC(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H08 compound treatment 0.224 0.0293 0.31 0.317 0.0349 0.42 0.5133 0.9887 3038952 ChemDiv3_014242 Cc1ccn2cc(CSc3ccccc3N)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H09 compound treatment 0.12 -0.0747 -0.78 0.157 -0.125 -1.5 -1.6127 -0.9546 3121486 ChemDiv3_014243 COC(CNC1=Nc2ncccc2OC1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H10 compound treatment 0.112 -0.0827 -0.87 0.231 -0.0511 -0.61 -1.0461 -0.9852 3121487 ChemDiv3_014244 COc1ccc2n3CN(CC4CCCO4)CN(Cc5ccccc5)c3nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H11 compound treatment 0.169 -0.0257 -0.27 0.327 0.0449 0.54 0.1894 0.3149 3039017 ChemDiv3_014245 CC1CCN(CC1)c2ccc(NC(=O)CCC(=O)O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H12 compound treatment 0.125 -0.0697 -0.73 0.077 -0.205 -2.45 -2.2524 -0.8797 3039018 ChemDiv3_014246 C(c1c[nH]c2ccccc12)c3nc(cs3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H13 compound treatment 1.508 1.31 13.79 1.438 1.16 13.83 19.5327 1.0 3039020 ChemDiv3_014247 Cc1ccc(o1)c2cc(nc(N)c2C#N)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H14 compound treatment 0.594 0.399 4.19 0.853 0.571 6.83 7.7957 0.9726 3039021 ChemDiv3_014248 CCN(C(=O)C)c1nc2c(s1)n(C(=O)C)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H15 compound treatment 0.522 0.327 3.44 0.829 0.547 6.54 7.058 0.9548 3039023 ChemDiv3_014249 CCn1cc(C(=O)OCC=C)c(=O)c2ccc(C)nc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H16 compound treatment 0.371 0.176 1.85 0.637 0.355 4.25 4.3122 0.9308 3039024 ChemDiv3_014250 CSc1nc(N)nc2sc(C(=O)c3ccc(Cl)cc3)c(N)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H17 compound treatment 0.249 0.0543 0.57 0.44 0.158 1.89 1.7395 0.8813 3039025 ChemDiv3_014251 O=C(CSc1nn2cnnc2s1)N(C3CCCCC3)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H18 compound treatment 0.151 -0.0437 -0.46 0.307 0.0249 0.3 -0.1135 -0.2073 3039027 ChemDiv3_014252 CC(C)(CC(=O)O)CC(=O)Nn1c(=O)c2ccccc2[nH]c1=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H19 compound treatment 0.259 0.0643 0.68 0.498 0.216 2.58 2.3045 0.863 3039028 ChemDiv3_014253 Cc1ccc2c(c1)sc3ncc(NC(=O)c4ccccc4)c(=O)n23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H20 compound treatment 0.594 0.399 4.19 0.72 0.438 5.24 6.6705 0.9939 3121488 ChemDiv3_014254 CC(C)CC1C(=C(C)Nc2c(cnn12)C(=O)Nc3ccccc3)C(=O)Nc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H21 compound treatment 0.169 -0.0257 -0.27 0.346 0.0639 0.76 0.3502 0.4317 3039030 ChemDiv3_014255 CC(C)CC1=NC(N=C(O1)N2CCCCC2)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H22 compound treatment 0.439 0.244 2.57 0.628 0.346 4.14 4.7411 0.9736 3121489 ChemDiv3_014256 CC(CNC(=O)c1cccc(Nc2nc3ccccc3n4cnnc24)c1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H23 mock treatment 0.205 0.0103 0.11 0.339 0.0569 0.68 0.5583 0.8094 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 H24 mock treatment 0.208 0.0133 0.14 0.288 0.00594 0.07 0.1491 0.9507 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I01 compound treatment 0.683 0.488 5.13 0.747 0.465 5.56 7.5599 0.9992 3039032 ChemDiv3_014257 Clc1ccc(NC(=O)Cc2ccc(cc2)n3cccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I02 compound treatment 0.076 -0.119 -1.25 0.096 -0.186 -2.23 -2.4555 -0.9624 1291873 ChemDiv3_014258 CCc1ccc(cc1)C2=NC(C)(CC)NC(C2)c3cc(Cl)ccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I03 compound treatment 0.222 0.0273 0.29 0.328 0.0459 0.55 0.5915 0.954 3121490 ChemDiv3_014259 COC(=O)CN(c1ccc(cc1)C(C)C)S(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I04 compound treatment 0.26 0.0653 0.69 0.397 0.115 1.38 1.4574 0.9484 1487708 ChemDiv3_014260 COc1ccc(NC(=O)c2sc3nc(C)nc(N(C)c4ccc(cc4)C(C)C)c3c2C)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I05 compound treatment 0.226 0.0313 0.33 0.36 0.0779 0.93 0.8919 0.902 3121491 ChemDiv3_014261 OC(=O)C(Cc1ccccc1)NS(=O)(=O)c2cccc3cccnc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I06 compound treatment 0.245 0.0503 0.53 0.402 0.12 1.43 1.3883 0.9079 1128308 ChemDiv3_014262 CCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NCc2ccccc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I07 compound treatment 0.2 0.00531 0.06 0.31 0.0279 0.33 0.2758 0.8139 3121492 ChemDiv3_014263 CN(C)/C=C/c1onc(C)c1S(=O)(=O)NCCN2CCC(Cc3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I08 compound treatment 0.244 0.0493 0.52 0.427 0.145 1.73 1.5924 0.8799 3121493 ChemDiv3_014264 Cc1ccccc1CN2CCN(CC2)C3c4ccccc4-c5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I09 compound treatment 0.21 0.0153 0.16 0.37 0.0879 1.05 0.8577 0.8058 3039037 ChemDiv3_014265 OC(=O)Cn1c(nc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I10 compound treatment 0.889 0.694 7.29 1.244 0.962 11.51 13.2944 0.9758 1211799 ChemDiv3_014266 O=C(NCc1ccco1)c2oc(=O)c3ccccc3c2c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I11 compound treatment 0.403 0.208 2.19 0.624 0.342 4.09 4.4399 0.957 3039039 ChemDiv3_014267 CCOC(=O)c1cc(c2ccc(F)cc2)n(CCC(=O)Nc3nc4ccc(C)cc4s3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I12 compound treatment 0.213 0.0183 0.19 0.39 0.108 1.29 1.0492 0.8036 1692523 ChemDiv3_014268 COc1cc2CCN(C(C)c2cc1OC)C(=O)CCN3C(=O)C4C5CC(C=C5)C4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I13 compound treatment 0.158 -0.0367 -0.39 0.367 0.0849 1.02 0.4461 0.4105 3121673 ChemDiv3_014269 Brc1cnc2NC(=NS(=O)(=O)c2c1)CCC(=O)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I14 compound treatment 0.172 -0.0227 -0.24 0.344 0.0619 0.74 0.3555 0.4567 3038955 ChemDiv3_014270 Cc1cc2c(=O)n(CC(=O)NCC(=O)N3CCCCC3)cnc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I15 compound treatment 0.608 0.413 4.34 0.904 0.622 7.44 8.3311 0.9671 3038956 ChemDiv3_014271 CCOC(=O)c1cc(c2ccccc2)n(CCCC(=O)NCc3ccccc3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I16 compound treatment 0.176 -0.0187 -0.2 0.348 0.0659 0.79 0.4191 0.5155 3038958 ChemDiv3_014272 C(=C/c1ccncc1)\c2ccncc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I17 compound treatment 0.277 0.0823 0.86 0.409 0.127 1.52 1.6852 0.9643 3038959 ChemDiv3_014273 CCC(Cc1ccccc1)NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I18 compound treatment 0.087 -0.108 -1.13 0.089 -0.193 -2.31 -2.4331 -0.946 1222646 ChemDiv3_014274 Nc1ccc(Oc2ccc3C(=O)N(Cc4ccco4)C(=O)c3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I19 compound treatment 0.241 0.0463 0.49 0.406 0.124 1.48 1.3925 0.8923 3038961 ChemDiv3_014275 O=c1ccc(n[nH]1)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I20 compound treatment 0.105 -0.0897 -0.94 0.603 0.321 3.84 2.0491 0.5183 3038962 ChemDiv3_014276 COC(=O)c1c(N)scc1c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I21 compound treatment 0.223 0.0283 0.3 0.37 0.0879 1.05 0.9542 0.8728 1455752 ChemDiv3_014277 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4)c12)C(=O)N5CCCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I22 compound treatment 0.183 -0.0117 -0.12 0.286 0.00394 0.05 -0.0535 -0.4068 3038964 ChemDiv3_014278 CC(Cn1ccnc1C)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I23 mock treatment 0.215 0.0203 0.21 0.287 0.00494 0.06 0.1926 0.8702 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 I24 mock treatment 0.239 0.0443 0.47 0.308 0.0259 0.31 0.5485 0.9806 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J01 compound treatment 0.23 0.0353 0.37 0.282 -6.25E-5 0.0 0.2617 0.7057 3038966 ChemDiv3_014279 NC(CC(=O)O)c1cccc(O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J02 compound treatment 0.239 0.0443 0.47 0.33 0.0479 0.57 0.7346 0.9946 3121674 ChemDiv3_014280 COc1ccc(cc1)C2=NC(N=C(O2)c3ccccc3C)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J03 compound treatment 0.205 0.0103 0.11 0.25 -0.0321 -0.38 -0.1947 -0.4884 1732489 ChemDiv3_014281 COc1cccc(Nc2ccc(cc2N)C(=O)O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J04 compound treatment 0.288 0.0933 0.98 0.403 0.121 1.45 1.7161 0.982 3121675 ChemDiv3_014282 Fc1ccccc1Cn2ccccc2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J05 compound treatment 0.127 -0.0677 -0.71 0.146 -0.136 -1.63 -1.6538 -0.931 3121676 ChemDiv3_014283 OC(=O)C1CN(Cc2ccc(F)cc2)C(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J06 compound treatment 0.37 0.175 1.84 0.486 0.204 2.44 3.0273 0.9904 3038969 ChemDiv3_014284 CSc1nsc(SCC(=O)OC2CC(C)CCC2C(C)C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J07 compound treatment 0.091 -0.104 -1.09 0.121 -0.161 -1.93 -2.1326 -0.9635 3121677 ChemDiv3_014285 OC(=O)CCSCc1ccc(Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J08 compound treatment 0.405 0.21 2.21 0.64 0.358 4.28 4.5901 0.9526 3121678 ChemDiv3_014286 COc1ccc(cc1)C2N(CCCN2S(=O)(=O)c3ccc(C)cc3)C(=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J09 compound treatment 0.115 -0.0797 -0.84 0.13 -0.152 -1.82 -1.8783 -0.9379 3038971 ChemDiv3_014287 OC(=O)Cn1c-2c(CSc3ccc(Cl)cc23)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J10 compound treatment 0.18 -0.0147 -0.15 0.354 0.0719 0.86 0.4995 0.5713 3121679 ChemDiv3_014288 CC1(C)CC(=O)C2=C(C1)NCN(CCCN3CCOCC3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J11 compound treatment 0.076 -0.119 -1.25 0.075 -0.207 -2.48 -2.6332 -0.9495 1032476 ChemDiv3_014289 CN1N=C(CC1=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J12 compound treatment 0.085 -0.11 -1.15 0.096 -0.186 -2.23 -2.3887 -0.953 1502309 ChemDiv3_014290 CC(=O)N1C2SC(=NC2(O)c3ccccc13)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J13 compound treatment 0.179 -0.0157 -0.16 0.314 0.0319 0.38 0.1537 0.3693 3038974 ChemDiv3_014291 CCC(Sc1nnc2sc3ccccc3n12)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J14 compound treatment 0.23 0.0353 0.37 0.376 0.0939 1.12 1.057 0.8931 3121680 ChemDiv3_014292 Fc1cccc(Cn2n(Cc3cccc(F)c3)c(=O)n(c4cccc(Cl)c4)c2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J15 compound treatment 1.23 1.04 10.87 1.339 1.06 12.65 16.6306 0.9972 3038976 ChemDiv3_014293 CCn1cc(C(=O)OCc2ccccc2)c(=O)c3ccc(C)nc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J16 compound treatment 0.281 0.0863 0.91 0.482 0.2 2.39 2.3325 0.9118 3039041 ChemDiv3_014294 CSc1nc2[nH]c(=O)cc(O)c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J17 compound treatment 0.267 0.0723 0.76 0.437 0.155 1.85 1.8478 0.9224 3039042 ChemDiv3_014295 Oc1ccc(cc1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J18 compound treatment 0.388 0.193 2.03 0.663 0.381 4.56 4.6584 0.9337 3039044 ChemDiv3_014296 COCCn1c(NN)nc2ccsc2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J19 compound treatment 0.414 0.219 2.3 0.515 0.233 2.79 3.5994 0.9955 3039045 ChemDiv3_014297 CCOC(=O)c1cc(NC(=O)c2ccccc2)c(=O)n3c4ccccc4oc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J20 compound treatment 0.294 0.0993 1.04 0.433 0.151 1.81 2.0145 0.966 3039047 ChemDiv3_014298 COC(=O)c1cc2ccc3OCN(Cc4ccccc4)Cc3c2oc1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J21 compound treatment 0.187 -0.00769 -0.08 0.229 -0.0531 -0.63 -0.506 -0.7907 3039049 ChemDiv3_014299 N/C(=N\C1=NC(N=C(O1)c2cccnc2)(C(F)(F)F)C(F)(F)F)/Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J22 compound treatment 0.316 0.121 1.27 0.489 0.207 2.48 2.6516 0.9523 3039050 ChemDiv3_014300 CCCOc1ccc(cc1)C(=O)Nc2c(NC)c3ccccc3oc2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J23 mock treatment 0.216 0.0213 0.22 0.335 0.0529 0.63 0.6061 0.9023 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 J24 mock treatment 0.203 0.00831 0.09 0.298 0.0159 0.19 0.1966 0.9373 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K01 compound treatment 0.208 0.0133 0.14 0.246 -0.0361 -0.43 -0.2062 -0.4547 3039052 ChemDiv3_014301 O=C(Cc1ccc(cc1)n2cccc2)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K02 compound treatment 0.129 -0.0657 -0.69 0.149 -0.133 -1.59 -1.6136 -0.93 1572441 ChemDiv3_014302 COC(=O)c1ccc(cc1)C2NC(CC(=N2)c3cccc(OC)c3)c4ccccc4O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K03 compound treatment 0.232 0.0373 0.39 0.345 0.0629 0.75 0.8096 0.9537 3121681 ChemDiv3_014303 CCOC(=O)c1cc(c2ccc(OC)cc2)n(CCC(=O)N3CCc4ccccc34)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K04 compound treatment 1.018 0.823 8.65 1.009 0.727 8.7 12.2643 1.0 1612615 ChemDiv3_014304 CCC(C)NC(=O)c1sc2nc(C)nc(N(C)c3ccc(cc3)C(C)C)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K05 compound treatment 0.306 0.111 1.17 0.411 0.129 1.54 1.9175 0.9906 3121682 ChemDiv3_014305 CCc1ccc(cc1)N(CC(=O)NC2CCCC2)S(=O)(=O)c3c(C)noc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K06 compound treatment 0.184 -0.0107 -0.11 0.363 0.0809 0.97 0.6054 0.621 1732890 ChemDiv3_014306 CCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NC2CCCCC2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K07 compound treatment 0.152 -0.0427 -0.45 0.353 0.0709 0.85 0.2831 0.295 3121683 ChemDiv3_014307 Clc1ccc(cc1)C2(C#N)N(Nc3ccccc32)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K08 compound treatment 0.222 0.0273 0.29 0.393 0.111 1.33 1.1414 0.8405 3121684 ChemDiv3_014308 Fc1ccccc1NC(=O)CCN2CCN(CC2)C3c4ccccc4-c5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K09 compound treatment 0.874 0.679 7.13 0.924 0.642 7.68 10.4758 0.9993 3039057 ChemDiv3_014309 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)N(C)Cc3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K10 compound treatment 0.224 0.0293 0.31 0.395 0.113 1.35 1.1732 0.8465 3121685 ChemDiv3_014310 Fc1ccccc1NC(=O)CCn2c(=S)oc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K11 compound treatment 0.353 0.158 1.66 0.495 0.213 2.55 2.9772 0.9786 3121686 ChemDiv3_014311 CCc1ccccc1NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCCC4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K12 compound treatment 0.226 0.0313 0.33 0.387 0.105 1.26 1.1203 0.8632 1689428 ChemDiv3_014312 Cc1ccc(cc1)S(=O)(=O)CCC(=O)Nc2nccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K13 compound treatment 0.182 -0.0127 -0.13 0.338 0.0559 0.67 0.379 0.5554 3039060 ChemDiv3_014313 CCOC(=O)c1ccc(n1C)S(=O)(=O)NC2CCCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K14 compound treatment 0.183 -0.0117 -0.12 0.38 0.0979 1.17 0.7418 0.6296 3121687 ChemDiv3_014314 COC(=O)CNC(=O)c1cc2c(=O)oc3ccccc3c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K15 compound treatment 0.422 0.227 2.39 0.681 0.399 4.77 5.0632 0.9487 3121688 ChemDiv3_014315 CCOC(=O)c1cc(c2ccc(C)cc2)n(CCCC(=O)Nc3cccc(CC)c3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K16 compound treatment 0.043 -0.152 -1.59 0.043 -0.239 -2.86 -3.149 -0.9618 3038992 ChemDiv3_014316 O=C(C/C=N/c1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K17 compound treatment 0.229 0.0343 0.36 0.431 0.149 1.78 1.5149 0.8332 3121689 ChemDiv3_014317 CCOC(=O)c1[nH]c(C)c(C(=O)NCCc2ccc(OC)c(OC)c2)c1CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K18 compound treatment 0.057 -0.138 -1.45 0.056 -0.226 -2.7 -2.9351 -0.957 3121690 ChemDiv3_014318 OC(=O)c1ccc(o1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K19 compound treatment 0.177 -0.0177 -0.19 0.313 0.0309 0.37 0.1304 0.3148 3121691 ChemDiv3_014319 O=c1ccc(n[nH]1)c2ccc(s2)S(=O)(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K20 compound treatment 0.095 -0.0997 -1.05 0.092 -0.19 -2.27 -2.3483 -0.938 1286152 ChemDiv3_014320 CC(=O)Nc1ccc(cc1)N2S(=O)(=O)c3ccccc3S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K21 compound treatment 1.154 0.959 10.08 1.176 0.894 10.7 14.6872 0.9996 1727899 ChemDiv3_014321 COc1cccc(NC(=O)c2sc3ncnc(N4CCc5ccccc5C4)c3c2C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K22 compound treatment 0.189 -0.00569 -0.06 0.33 0.0479 0.57 0.3633 0.6301 3037892 ChemDiv3_014322 CC1=CC=CC2=NC(=O)CC(C)(N12)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K23 mock treatment 0.159 -0.0357 -0.37 0.288 0.00594 0.07 -0.2148 -0.5631 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 K24 mock treatment 0.216 0.0213 0.22 0.262 -0.0201 -0.24 -0.0115 -0.0349 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L01 compound treatment 0.286 0.0913 0.96 0.388 0.106 1.27 1.5744 0.9905 3121692 ChemDiv3_014323 FC(F)(F)C1=CC(=O)c2cccc3c(NC4CCCCC4)ccc1c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L02 compound treatment 0.241 0.0463 0.49 0.318 0.0359 0.43 0.648 0.9981 3037895 ChemDiv3_014324 Cc1ccc(cc1)C2=NC(N=C(O2)c3ccco3)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L03 compound treatment 0.222 0.0273 0.29 0.296 0.0139 0.17 0.3207 0.9667 3121693 ChemDiv3_014325 Nc1cc(ccc1NCCCN2CCOCC2)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L04 compound treatment 0.276 0.0813 0.85 0.435 0.153 1.83 1.8977 0.9398 3037896 ChemDiv3_014326 Clc1ccc(cc1)C(=O)OCC2CC(=NO2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L05 compound treatment 0.186 -0.00869 -0.09 0.258 -0.0241 -0.29 -0.2681 -0.8877 3121694 ChemDiv3_014327 COc1ccc(cc1)C(N)CCc2ccc(C)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L06 compound treatment 0.497 0.302 3.18 0.627 0.345 4.13 5.1633 0.9916 3121695 ChemDiv3_014328 CC1(C)CC(=O)c2cc(NC(=O)c3ccccc3)c(=O)oc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L07 compound treatment 0.18 -0.0147 -0.15 0.26 -0.0221 -0.26 -0.2957 -0.9673 3037899 ChemDiv3_014329 OC(=O)CSCc1ccc(F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L08 compound treatment 0.331 0.136 1.43 0.556 0.274 3.28 3.3299 0.931 3037900 ChemDiv3_014330 Cc1cc(C)nc(n1)n2cc3c(=O)[nH]c(=S)nc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L09 compound treatment 1.061 0.866 9.1 1.233 0.951 11.38 14.4787 0.9939 3121877 ChemDiv3_014331 COC(=O)CC1Oc2ccccc2N(Cc3ccc(C)cc3)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L10 compound treatment 0.149 -0.0457 -0.48 0.244 -0.0381 -0.46 -0.6613 -0.9997 3121878 ChemDiv3_014332 Cc1ccc(NC2=NC(c3ccccc3)n4c(N2)nc(C)cc4=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L11 compound treatment 0.182 -0.0127 -0.13 0.345 0.0629 0.75 0.4382 0.5731 1689444 ChemDiv3_014333 Clc1ccc(CNc2nc3ccccc3[nH]2)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L12 compound treatment 0.151 -0.0437 -0.46 0.272 -0.0101 -0.12 -0.4096 -0.8634 1308505 ChemDiv3_014334 CC(=O)n1c2sc(N)nc2c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L13 compound treatment 0.11 -0.0847 -0.89 0.121 -0.161 -1.93 -1.9915 -0.9384 3121879 ChemDiv3_014335 O=C(CSc1nnc2sc3ccccc3n12)N4N=CCC4c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L14 compound treatment 0.452 0.257 2.7 0.626 0.344 4.12 4.8207 0.9792 3037941 ChemDiv3_014336 Cc1n[nH]c(NC2=CC(=O)CC(C2)c3ccc(C)cc3)c1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L15 compound treatment 0.258 0.0633 0.66 0.37 0.0879 1.05 1.2142 0.9755 3121880 ChemDiv3_014337 Cc1ccccc1NS(=O)(=O)c2ccc3n(C)c(=O)n(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L16 compound treatment 0.16 -0.0347 -0.36 0.312 0.0299 0.36 -0.0043 -0.0085 3121881 ChemDiv3_014338 O=C(N1CCCCC1)/C(=C/2\C(=O)Nc3ccccc23)/C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L17 compound treatment 0.222 0.0273 0.29 0.372 0.0899 1.08 0.9637 0.8654 3037943 ChemDiv3_014339 CC(C)CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L18 compound treatment 0.299 0.104 1.1 0.495 0.213 2.55 2.5762 0.9289 3121882 ChemDiv3_014340 CC(C)Cn1c(=O)c2sccc2n3c(CCCC(=O)N(C)Cc4ccco4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L19 compound treatment 0.375 0.18 1.89 0.49 0.208 2.49 3.0983 0.9909 3121883 ChemDiv3_014341 COc1ccc2[nH]cc(CCNC(=O)NC3(C[C@H]4C[C@@H]5C[C@H](C4)C3)C5)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L20 compound treatment 0.305 0.11 1.16 0.419 0.137 1.64 1.9777 0.9856 3037946 ChemDiv3_014342 Cc1cccc(c1)N2C(=O)NC3CC2(C)Oc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L21 compound treatment 0.398 0.203 2.14 0.696 0.414 4.95 5.0119 0.9293 3121884 ChemDiv3_014343 FC(F)(F)C1(C2CC(C=C2)N1S(=O)(=O)c3ccccc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L22 compound treatment 0.173 -0.0217 -0.23 0.297 0.0149 0.18 -0.0347 -0.1198 3037948 ChemDiv3_014344 CCOC(=O)CC(=O)Nc1c(NC)c2ccccc2oc1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L23 mock treatment 0.19 -0.00469 -0.05 0.273 -0.00906 -0.11 -0.1115 -0.9362 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 L24 mock treatment 0.179 -0.0157 -0.16 0.241 -0.0411 -0.49 -0.4639 -0.8952 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M01 compound treatment 0.267 0.0723 0.76 0.308 0.0259 0.31 0.7565 0.922 3121885 ChemDiv3_014345 Cc1n[nH]c(C)c1S(=O)(=O)N(CC(=O)O)c2cc(C)cc(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M02 compound treatment 0.24 0.0453 0.48 0.352 0.0699 0.84 0.9282 0.9642 1647178 ChemDiv3_014346 CC(C)C1(C)NC(CC(=N1)c2ccc3OCOc3c2)c4ccccc4O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M03 compound treatment 0.167 -0.0277 -0.29 0.273 -0.00906 -0.11 -0.2823 -0.9096 3121886 ChemDiv3_014347 CC12CC(C)(C)NC(=S)N2C(C(=O)O1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M04 compound treatment 0.241 0.0463 0.49 0.381 0.0989 1.18 1.181 0.9228 1697357 ChemDiv3_014348 Fc1ccc(cc1)S(=O)(=O)NC(Cc2ccccc2)C(=O)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M05 compound treatment 0.169 -0.0257 -0.27 0.3 0.0179 0.21 -0.039 -0.1132 3037952 ChemDiv3_014349 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCC(C3)C(=O)NN4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M06 compound treatment 0.117 -0.0777 -0.82 0.173 -0.109 -1.3 -1.4996 -0.9744 3121887 ChemDiv3_014350 O=C/1Nc2ccccc2\C1=C\C3CCC=CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M07 compound treatment 0.274 0.0793 0.83 0.474 0.192 2.3 2.2128 0.9058 3121888 ChemDiv3_014351 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)N(C)C3CCCCC3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M08 compound treatment 0.372 0.177 1.86 0.539 0.257 3.07 3.4905 0.9712 3037954 ChemDiv3_014352 FC(F)(F)c1cccc(NC(=O)CCN2CCN(CC2)C3c4ccccc4-c5ccccc35)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M09 compound treatment 0.173 -0.0217 -0.23 0.34 0.0579 0.69 0.3291 0.451 3121889 ChemDiv3_014353 Cn1cnc(c1)S(=O)(=O)Nc2cccc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M10 compound treatment 0.238 0.0433 0.45 0.383 0.101 1.21 1.1756 0.911 3121890 ChemDiv3_014354 CCc1ccccc1N(C)C(=O)CCn2c(=S)oc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M11 compound treatment 0.175 -0.0197 -0.21 0.326 0.0439 0.53 0.2255 0.3992 3121891 ChemDiv3_014355 O=C(Nc1ccc(cc1)C(=O)N2CCCCC2)c3ccc(=O)[nH]c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M12 compound treatment 0.262 0.0673 0.71 0.405 0.123 1.47 1.54 0.9436 1616530 ChemDiv3_014356 CCOc1ccc(OCC)c(NC(=O)CCS(=O)(=O)c2ccc(C)cc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M13 compound treatment 0.201 0.00631 0.07 0.344 0.0619 0.74 0.5709 0.7673 3121892 ChemDiv3_014357 COC(=O)c1ccc(n1C)S(=O)(=O)NCc2cccc(OC)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M14 compound treatment 0.221 0.0263 0.28 0.337 0.0549 0.66 0.6602 0.9259 1631137 ChemDiv3_014358 COC(=O)CNC(=O)c1nn(c2ccc(OC)cc2OC)c(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M15 compound treatment 0.771 0.576 6.05 1.025 0.743 8.89 10.5653 0.9825 3121893 ChemDiv3_014359 CCOC(=O)c1cc(c2ccccc2)n(CCCC(=O)N3CCCCC3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M16 compound treatment 0.16 -0.0347 -0.36 0.351 0.0689 0.82 0.3256 0.3611 1003750 ChemDiv3_014360 COc1ccc(CC(=O)O)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M17 compound treatment 0.164 -0.0307 -0.32 0.296 0.0139 0.17 -0.11 -0.3031 3121894 ChemDiv3_014361 O=c1ccc2cc(ccc2[nH]1)S(=O)(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M18 compound treatment 0.161 -0.0337 -0.35 0.315 0.0329 0.39 0.0285 0.0538 1732260 ChemDiv3_014362 NC(=O)C1CCN(CC1)C(=O)C2C(C3CCC2C3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M19 compound treatment 0.255 0.0603 0.63 0.431 0.149 1.78 1.7079 0.9031 3121895 ChemDiv3_014363 COc1ccc(CCC(=O)Nc2ccc(cc2)c3noc(CCc4ccccc4)n3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M20 compound treatment 0.197 0.00231 0.02 0.347 0.0649 0.78 0.5666 0.7289 1644077 ChemDiv3_014364 CC(C)(C)c1cc([nH]n1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M21 compound treatment 0.098 -0.0967 -1.02 0.128 -0.154 -1.84 -2.0214 -0.9605 3121896 ChemDiv3_014365 CC(C)CC1NC(CC(=N1)c2ccc(C)cc2)c3ccccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M22 compound treatment 0.208 0.0133 0.14 0.352 0.0699 0.84 0.6905 0.814 3038008 ChemDiv3_014366 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)O)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M23 mock treatment 0.155 -0.0397 -0.42 0.275 -0.00706 -0.08 -0.3545 -0.8335 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 M24 mock treatment 0.206 0.0113 0.12 0.263 -0.0191 -0.23 -0.0773 -0.3004 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N01 compound treatment 0.042 -0.153 -1.6 0.042 -0.24 -2.87 -3.1649 -0.9621 1671367 ChemDiv3_014367 NNc1ccc2c(Cl)cc(Cl)c(O)c2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N02 compound treatment 0.189 -0.00569 -0.06 0.287 0.00494 0.06 -5.0E-4 -0.0055 3121897 ChemDiv3_014368 CCOC(=O)c1ccc(cc1)N2C(=O)NC(C3=C2CC(C)(C)CC3=O)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N03 compound treatment 0.258 0.0633 0.66 0.39 0.108 1.29 1.3834 0.9524 3038011 ChemDiv3_014369 OC(=O)CCN1C(=O)CC2(CCCCC2)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N04 compound treatment 0.196 0.00131 0.01 0.296 0.0139 0.17 0.1277 0.763 3038012 ChemDiv3_014370 Nc1ncnc2n(CCN3CCCCC3)cnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N05 compound treatment 0.191 -0.00369 -0.04 0.32 0.0379 0.45 0.2936 0.6444 3121898 ChemDiv3_014371 CCC(C)N1C(CCC1=O)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N06 compound treatment 0.269 0.0743 0.78 0.34 0.0579 0.69 1.042 0.9983 3121899 ChemDiv3_014372 Nc1ccccc1NC(=O)c2nc3ccccc3nc2C(O)C(O)CO 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N07 compound treatment 0.197 0.00231 0.02 0.399 0.117 1.4 1.0065 0.7193 3038015 ChemDiv3_014373 OC(=O)C1CN(C2CCCC2)C(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N08 compound treatment 0.227 0.0323 0.34 0.373 0.0909 1.09 1.0093 0.8856 3121900 ChemDiv3_014374 CCOC(=O)C1C(NC(=NC1=O)N2CCc3ccccc23)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N09 compound treatment 0.191 -0.00369 -0.04 0.335 0.0529 0.63 0.4205 0.6626 3038017 ChemDiv3_014375 OC(=O)Cn1cc2CCCCc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N10 compound treatment 0.234 0.0393 0.41 0.418 0.136 1.63 1.442 0.8594 3121901 ChemDiv3_014376 Cc1nc2ccccc2c3N=C(CC(=O)c13)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N11 compound treatment 0.394 0.199 2.09 0.611 0.329 3.94 4.2631 0.9563 1871098 ChemDiv3_014377 COc1ccc(cc1)C2C3=C(Nc4[nH]c(=O)[nH]c(=O)c24)c5ccccc5C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N12 compound treatment 1.275 1.08 11.35 1.289 1.01 12.05 16.5418 0.9996 3121902 ChemDiv3_014378 CC(=O)n1c2sc(C)nc2c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N13 compound treatment 0.189 -0.00569 -0.06 0.369 0.0869 1.04 0.6933 0.6654 3121903 ChemDiv3_014379 COc1cc2CCN(Cc2cc1OC)C(=O)CSc3nnc4ccc5ccccc5n34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N14 compound treatment 0.106 -0.0887 -0.93 0.115 -0.167 -2.0 -2.072 -0.9396 3038019 ChemDiv3_014380 CSc1nc(N)nc2sc(C(=O)C3(CC4CC5CC(C4)C3)C5)c(N)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N15 compound treatment 0.169 -0.0257 -0.27 0.347 0.0649 0.78 0.3586 0.436 3122086 ChemDiv3_014381 Cn1c(=O)n(C)c2cc(ccc12)S(=O)(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N16 compound treatment 0.068 -0.127 -1.33 0.072 -0.21 -2.51 -2.718 -0.9558 3038075 ChemDiv3_014382 Fc1ccc(cc1)S(=O)(=O)N2CCCCC2C(=O)OCc3ccc(Br)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N17 compound treatment 0.444 0.249 2.62 0.676 0.394 4.71 5.1843 0.9615 3038077 ChemDiv3_014383 CCc1ccc2oc(nc2c1)c3cc(N)cc(C)c3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N18 compound treatment 0.167 -0.0277 -0.29 0.285 0.00294 0.04 -0.1808 -0.6172 3122087 ChemDiv3_014384 O=c1[nH]ccn(c2ccccc2)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N19 compound treatment 0.194 -6.88E-4 -0.01 0.307 0.0249 0.3 0.2059 0.6898 3122088 ChemDiv3_014385 NC1=NC2(CCN(Cc3ccccc3)CC2)n4c(N1)nc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N20 compound treatment 0.181 -0.0137 -0.14 0.332 0.0499 0.6 0.3208 0.5221 3038079 ChemDiv3_014386 NC1=NC(N(C(=N1)N)c2ccc(F)c(Cl)c2)c3ccccc3C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N21 compound treatment 0.236 0.0413 0.43 0.332 0.0499 0.6 0.7293 0.9877 3122089 ChemDiv3_014387 FC(F)(F)C1(NN(C(=N1)c2cccnc2)c3ccccc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N22 compound treatment 0.151 -0.0437 -0.46 0.226 -0.0561 -0.67 -0.7987 -0.9829 3038081 ChemDiv3_014388 CNc1c(NC(=O)c2cccc(F)c2)c(=O)oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N23 mock treatment 0.211 0.0163 0.17 0.27 -0.0121 -0.14 0.0191 0.0852 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 N24 mock treatment 0.16 -0.0347 -0.36 0.231 -0.0511 -0.61 -0.6896 -0.9695 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O01 compound treatment 0.274 0.0793 0.83 0.263 -0.0191 -0.23 0.4277 0.4953 3122090 ChemDiv3_014389 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N(C)c3ccc(C)cc3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O02 compound treatment 0.202 0.00731 0.08 0.248 -0.0341 -0.41 -0.2339 -0.5639 3122091 ChemDiv3_014390 CCOc1ccc(cc1)C2=NC3(CCN(CC3)C(C)C)NC(C2)c4cc(Cl)ccc4O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O03 compound treatment 0.214 0.0193 0.2 0.261 -0.0211 -0.25 -0.0348 -0.1075 3038083 ChemDiv3_014391 OC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O04 compound treatment 0.387 0.192 2.02 0.454 0.172 2.06 2.8828 1.0 3122092 ChemDiv3_014392 CC1CCCCC1NC(=O)c2cccc(NS(=O)(=O)c3ccc(Br)cc3)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O05 compound treatment 0.219 0.0243 0.26 0.271 -0.0111 -0.13 0.087 0.3024 3038085 ChemDiv3_014393 O=C(NC1CCCCC1)C2CCCN2S(=O)(=O)c3ccc4NC(=O)CCc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O06 compound treatment 0.042 -0.153 -1.6 0.044 -0.238 -2.85 -3.148 -0.9631 3122093 ChemDiv3_014394 O=C/1Nc2ccccc2\C1=C\c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O07 compound treatment 0.453 0.258 2.71 0.569 0.287 3.43 4.3459 0.9932 3038087 ChemDiv3_014395 CN(C)/C=C/c1onc(C)c1S(=O)(=O)N2CCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O08 compound treatment 0.17 -0.0247 -0.26 0.284 0.00194 0.02 -0.167 -0.6413 1667350 ChemDiv3_014396 Cc1ccccc1CN2CCN(CC2)C(=O)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O09 compound treatment 0.226 0.0313 0.33 0.333 0.0509 0.61 0.6635 0.9581 3038090 ChemDiv3_014397 Cc1ccc(NS(=O)(=O)c2cn(C)cn2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O10 compound treatment 0.17 -0.0247 -0.26 0.335 0.0529 0.63 0.2645 0.3865 1501444 ChemDiv3_014398 O=C(NC1CCCC1)C2CCCN2C(=O)OCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O11 compound treatment 0.166 -0.0287 -0.3 0.343 0.0609 0.73 0.3025 0.3834 3122094 ChemDiv3_014399 CC1CC(C)CN(C1)C(=O)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O12 compound treatment 0.214 0.0193 0.2 0.37 0.0879 1.05 0.8874 0.8282 3038091 ChemDiv3_014400 CCc1ccc(NC(=O)CCS(=O)(=O)c2ccc(Br)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O13 compound treatment 0.162 -0.0327 -0.34 0.293 0.0109 0.13 -0.1502 -0.4089 3122095 ChemDiv3_014401 Nc1ncc(Br)cc1S(=O)(=O)NCc2cccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O14 compound treatment 0.277 0.0823 0.86 0.408 0.126 1.51 1.6767 0.9652 1512154 ChemDiv3_014402 CCCCN(CC)C(=O)c1nn(c2ccc(OC)cc2)c(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O15 compound treatment 0.243 0.0483 0.51 0.36 0.0779 0.93 1.0182 0.9591 3122096 ChemDiv3_014403 CN(C)/C=C/c1onc(C)c1S(=O)(=O)Nc2cccc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O16 compound treatment 1.237 1.04 10.95 1.294 1.01 12.11 16.3019 0.9987 1032481 ChemDiv3_014404 CCCCC(=O)c1ccc(O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O17 compound treatment 0.198 0.00331 0.03 0.286 0.00394 0.05 0.0579 0.9889 3122097 ChemDiv3_014405 Cc1cc(NS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)ccc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O18 compound treatment 0.396 0.201 2.11 0.572 0.29 3.47 3.948 0.9718 1468252 ChemDiv3_014406 CCOC(=O)c1cc(c2ccccc2)n(c1C)c3ccc(cc3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O19 compound treatment 0.389 0.194 2.04 0.492 0.21 2.51 3.2192 0.9947 3122098 ChemDiv3_014407 Brc1ccc(OCc2nc(no2)c3ccc(NC(=O)c4cccnc4)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O20 compound treatment 0.258 0.0633 0.66 0.288 0.00594 0.07 0.5204 0.7782 1591637 ChemDiv3_014408 OC(=O)c1n[nH]c2CCCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O21 compound treatment 0.074 -0.121 -1.27 0.086 -0.196 -2.35 -2.555 -0.9582 1788098 ChemDiv3_014409 CC(C)C1NC(CC(=N1)c2ccc(C)cc2)c3ccccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O22 compound treatment 0.208 0.0133 0.14 0.233 -0.0491 -0.59 -0.3162 -0.524 3037969 ChemDiv3_014410 OC(=O)c1c[nH]nc1c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O23 mock treatment 0.184 -0.0107 -0.11 0.223 -0.0591 -0.71 -0.579 -0.8093 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 O24 mock treatment 0.214 0.0193 0.2 0.263 -0.0191 -0.23 -0.0178 -0.0585 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P01 compound treatment 0.262 0.0673 0.71 0.298 0.0159 0.19 0.6347 0.8669 1024926 ChemDiv3_014411 C1CN(CCN1)C(c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P02 compound treatment 0.228 0.0333 0.35 0.299 0.0169 0.2 0.3907 0.9663 3122099 ChemDiv3_014412 CC(N1C(=NC(C2=C1CC(C)(C)CC2=O)(C(F)(F)F)C(F)(F)F)C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P03 compound treatment 0.502 0.307 3.23 0.617 0.335 4.01 5.1159 0.9942 3038022 ChemDiv3_014413 OC(=O)CNC(=S)N(Cc1cccs1)Cc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P04 compound treatment 0.865 0.67 7.04 0.967 0.685 8.19 10.7727 0.9971 3122100 ChemDiv3_014414 Cc1cc(=O)oc2cc(OCC3CC(=NO3)c4ccccc4)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P05 compound treatment 0.396 0.201 2.11 0.522 0.24 2.87 3.525 0.9887 1518015 ChemDiv3_014415 Cc1ccc(cc1C)N2CC(CC2=O)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P06 compound treatment 0.21 0.0153 0.16 0.316 0.0339 0.41 0.4008 0.9178 1048613 ChemDiv3_014416 Oc1c(O)c(CN2CCOCC2)ccc1CN3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P07 compound treatment 0.22 0.0253 0.27 0.287 0.00494 0.06 0.2298 0.8437 3122101 ChemDiv3_014417 OC(=O)C1CN(CCc2ccccc2)C(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P08 compound treatment 0.191 -0.00369 -0.04 0.272 -0.0101 -0.12 -0.1125 -0.8897 3038025 ChemDiv3_014418 Nc1nc(Nc2ccccc2)c3C(=O)CC(Cc3n1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P09 compound treatment 0.21 0.0153 0.16 0.324 0.0419 0.5 0.4685 0.8892 1459526 ChemDiv3_014419 Cc1nc2cc(ccc2n1c3ccc(Br)cc3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P10 compound treatment 0.2 0.00531 0.06 0.284 0.00194 0.02 0.0558 0.9243 3122102 ChemDiv3_014420 Cc1cc(C)nc(NC2=NCN(Cc3ccccc3)CN2Cc4ccccc4)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P11 compound treatment 0.284 0.0893 0.94 0.388 0.106 1.27 1.5595 0.989 3038027 ChemDiv3_014421 CSC1=N/C(=C\c2c(C)nn(c2Cl)c3ccccc3)/C(=O)S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P12 compound treatment 0.185 -0.00969 -0.1 0.301 0.0189 0.23 0.0883 0.3554 3122103 ChemDiv3_014422 CC(=O)n1c2sc(nc2c3ccccc13)c4ccncc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P13 compound treatment 0.357 0.162 1.7 0.483 0.201 2.4 2.9054 0.9858 3038029 ChemDiv3_014423 CC(C1CC(=O)N(Cc2ccco2)C1=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P14 compound treatment 0.076 -0.119 -1.25 0.079 -0.203 -2.43 -2.5994 -0.9519 3122104 ChemDiv3_014424 Cc1ccc(SCC2=NNC(=O)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P15 compound treatment 0.241 0.0463 0.49 0.303 0.0209 0.25 0.5211 0.9524 3122105 ChemDiv3_014425 Oc1ccc(Cl)cc1C(CC(=O)N2CCCCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P16 compound treatment 0.189 -0.00569 -0.06 0.253 -0.0291 -0.35 -0.2881 -0.8166 3038032 ChemDiv3_014426 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P17 compound treatment 0.226 0.0313 0.33 0.274 -0.00806 -0.1 0.1643 0.4795 1174453 ChemDiv3_014427 CC(=O)Nc1ccc(NC2SC(=O)NC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P18 compound treatment 1.068 0.873 9.17 1.173 0.891 10.66 14.0231 0.9972 3038034 ChemDiv3_014428 Cc1ccc(cc1)c2n[nH]c3NC4=C(C(c23)c5ccccc5)C(=O)CC(C)(C)C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P19 compound treatment 0.192 -0.00269 -0.03 0.309 0.0269 0.32 0.2079 0.6427 3122106 ChemDiv3_014429 CC1CC(=O)C2=C(C1)Nc3ncnn3C2c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P20 compound treatment 0.22 0.0253 0.27 0.243 -0.0391 -0.47 -0.1425 -0.265 3122107 ChemDiv3_014430 Cc1cc(C)cc(c1)N2C(N=C(N)N=C2N)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P21 compound treatment 0.25 0.0553 0.58 0.306 0.0239 0.29 0.6133 0.9469 3038092 ChemDiv3_014431 CC1=CC2=NC(N=C(C)N2C=C1)(C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P22 compound treatment 0.16 -0.0347 -0.36 0.221 -0.0611 -0.73 -0.7742 -0.9483 3122108 ChemDiv3_014432 CCNc1c(NC(=O)CC2(CC3CC4CC(C3)C2)C4)c(=O)oc5ccccc15 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P23 mock treatment 0.182 -0.0127 -0.13 0.312 0.0299 0.36 0.1591 0.4162 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2041 P24 mock treatment 0.192 -0.00269 -0.03 0.233 -0.0491 -0.59 -0.435 -0.7403 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A01 compound treatment 0.092 -0.0916 -0.96 0.112 -0.122 -1.46 -1.7128 -0.9795 3122109 ChemDiv3_014433 Oc1c(NC(=O)CC2(CC3CC4CC(C3)C2)C4)c(=O)oc5ccccc15 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A02 compound treatment 0.463 0.279 2.93 0.579 0.345 4.13 4.9933 0.986 3038095 ChemDiv3_014434 COc1cc2CCN(C(c3ccccc3)c2cc1OC)C(=O)c4oc5ccccc5c4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A03 compound treatment 0.216 0.0324 0.34 0.255 0.0209 0.25 0.4179 0.9886 3122292 ChemDiv3_014435 OC(=O)c1ccc(Cn2nc(ccc2=O)N3CCCCC3)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A04 compound treatment 0.269 0.0854 0.9 0.3 0.0659 0.79 1.1922 0.9979 3038097 ChemDiv3_014436 C(Nc1noc2ccccc12)Nc3noc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A05 compound treatment 0.166 -0.0176 -0.18 0.243 0.00894 0.11 -0.055 -0.2576 3122293 ChemDiv3_014437 Cc1ccc(cc1)S(=O)(=O)c2cc3cc(ccc3oc2=O)C(=O)Nc4ccc(C)c(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A06 compound treatment 0.701 0.517 5.43 0.744 0.51 6.1 8.1567 0.9983 3038099 ChemDiv3_014438 COc1ccc(NC(=O)C(C)Oc2ccc3c(cc(=O)oc3c2)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A07 compound treatment 0.833 0.649 6.82 0.816 0.582 6.96 9.7462 0.9999 3122294 ChemDiv3_014439 CCNc1cc(N(C)C)c2noc3-c4ccccc4C(=O)c1c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A08 compound treatment 0.156 -0.0276 -0.29 0.222 -0.0121 -0.14 -0.3069 -0.9483 3122295 ChemDiv3_014440 Cc1nnc(SCC(=O)NC2CCCCC2)nc1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A09 compound treatment 0.132 -0.0516 -0.54 0.18 -0.0541 -0.65 -0.8405 -0.9961 3038100 ChemDiv3_014441 CN(C)c1nc2cc3c(C)c(oc3cc2s1)C(=O)N4CCC(CC4)C(=O)N5CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A10 compound treatment 0.452 0.268 2.82 0.5 0.266 3.18 4.2433 0.9982 3122296 ChemDiv3_014442 CCCCC(CC)CN1CC(=O)C(=C1N)c2nc3ccccc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A11 compound treatment 0.249 0.0654 0.69 0.28 0.0459 0.55 0.8745 0.9939 3122297 ChemDiv3_014443 CCOC(=O)C1=C(C)NC(CS1)C(=O)NCCCN2CC(C)CC(C)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A12 compound treatment 0.157 -0.0266 -0.28 0.161 -0.0731 -0.87 -0.8155 -0.8887 1492617 ChemDiv3_014444 O=C(Nc1ccc(cc1)c2ccccc2)C3=C4Nc5ccccc5N4CCC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A13 compound treatment 0.134 -0.0496 -0.52 0.199 -0.0351 -0.42 -0.6649 -0.9943 3122298 ChemDiv3_014445 CCCN(CCC)C(=O)CSc1nc2cccnc2[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A14 compound treatment 0.225 0.0414 0.44 0.327 0.0929 1.11 1.0938 0.9161 3038102 ChemDiv3_014446 CCOc1nc2n(C)cnc2c(=O)n1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A15 compound treatment 0.152 -0.0316 -0.33 0.208 -0.0261 -0.31 -0.455 -0.9995 3122299 ChemDiv3_014447 CCOC(=O)N1CCC(CC1)Nc2nc3ccc(Cl)cc3n4cnnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A16 compound treatment 0.289 0.105 1.11 0.287 0.0529 0.63 1.2307 0.9649 3122300 ChemDiv3_014448 O=C(NCc1nc(no1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A17 compound treatment 0.958 0.774 8.13 0.961 0.727 8.7 11.9012 0.9994 3038104 ChemDiv3_014449 CCn1c(cc2oc3ccccc3c12)C(=O)NCCCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A18 compound treatment 0.246 0.0624 0.66 0.267 0.0329 0.39 0.7422 0.9703 3122301 ChemDiv3_014450 CCOc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3CCCc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A19 compound treatment 0.21 0.0264 0.28 0.226 -0.00806 -0.1 0.128 0.4356 3038105 ChemDiv3_014451 COCc1nc2cc(C)ccc2[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A20 compound treatment 0.181 -0.00258 -0.03 0.259 0.0249 0.3 0.1918 0.6402 3122302 ChemDiv3_014452 FC(F)(F)c1cccc(c1)N2C3CS(=O)(=O)CC3SC2=N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A21 compound treatment 0.202 0.0184 0.19 0.28 0.0459 0.55 0.5254 0.9018 3038415 ChemDiv3_014453 Oc1nc2ccccc2cc1CN(C(=O)c3cccc(Cl)c3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A22 compound treatment 0.341 0.157 1.65 0.42 0.186 2.22 2.7421 0.9893 3038417 ChemDiv3_014454 COc1cccc(c1)c2coc3cc4oc(=O)cc(C)c4cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A23 mock treatment 0.203 0.0194 0.2 0.253 0.0189 0.23 0.3044 0.9986 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 A24 mock treatment 0.223 0.0394 0.41 0.293 0.0589 0.71 0.7914 0.9678 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B01 compound treatment 0.306 0.122 1.29 0.352 0.118 1.41 1.9069 0.9989 3122303 ChemDiv3_014455 Cc1c(CC(=O)O)c(=O)oc2c(C)c3occ(c4ccc(Br)cc4)c3cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B02 compound treatment 0.353 0.169 1.78 0.428 0.194 2.32 2.8989 0.9914 3122304 ChemDiv3_014456 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)N3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B03 compound treatment 0.164 -0.0196 -0.21 0.202 -0.0321 -0.38 -0.4167 -0.9573 3038455 ChemDiv3_014457 COc1cccc(CN2COc3ccc4c(cc(=O)oc4c3C2)c5ccccc5)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B04 compound treatment 0.097 -0.0866 -0.91 0.098 -0.136 -1.63 -1.7941 -0.9622 3122305 ChemDiv3_014458 CN(Cc1csc(C)c1C)Cc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B05 compound treatment 0.3 0.116 1.22 0.379 0.145 1.73 2.0908 0.9854 3038457 ChemDiv3_014459 Cc1ccc(cc1)n2nnc3c(sc4nc(C)cc(C)c43)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B06 compound treatment 0.479 0.295 3.1 0.545 0.311 3.72 4.8245 0.9959 3122306 ChemDiv3_014460 OC(=O)CSCc1csc2CCCCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B07 compound treatment 0.106 -0.0776 -0.81 0.121 -0.113 -1.35 -1.5327 -0.9706 3038459 ChemDiv3_014461 CN(Cc1ccco1)Cc2cc(=O)oc3cc(C)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B08 compound treatment 0.29 0.106 1.12 0.351 0.117 1.4 1.7796 0.9938 3122307 ChemDiv3_014462 CCOC(=O)CC1NCCc2cc(OCC)c(OCC)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B09 compound treatment 0.104 -0.0796 -0.84 0.125 -0.109 -1.3 -1.5137 -0.9768 1229726 ChemDiv3_014463 CC(C)N(C(=O)CSCc1nc2ccccc2[nH]1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B10 compound treatment 0.203 0.0194 0.2 0.284 0.0499 0.6 0.5667 0.8976 3038462 ChemDiv3_014464 NC(=O)c1cc(cs1)S(=O)(=O)NC2CCCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B11 compound treatment 0.51 0.326 3.43 0.671 0.437 5.23 6.1207 0.9791 3122308 ChemDiv3_014465 CC(C(=O)N1CCc2ccccc12)n3sc4ccccc4c3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B12 compound treatment 0.165 -0.0186 -0.2 0.243 0.00894 0.11 -0.0624 -0.2804 3038466 ChemDiv3_014466 CCc1ccccc1NC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B13 compound treatment 0.224 0.0404 0.42 0.269 0.0349 0.42 0.5957 1.0 3122309 ChemDiv3_014467 CC(C)C(=O)Nc1nn2c(nnc2s1)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B14 compound treatment 0.244 0.0604 0.63 0.301 0.0669 0.8 1.015 0.9934 3122310 ChemDiv3_014468 CC1CCCC(NC(=O)Cn2c(cc3ccccc23)c4cccs4)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B15 compound treatment 0.222 0.0384 0.4 0.306 0.0719 0.86 0.8939 0.9404 3122311 ChemDiv3_014469 CCOc1ccc(CCNc2nnc3c4ccccc4n(CC)c3n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B16 compound treatment 0.127 -0.0566 -0.59 0.16 -0.0741 -0.89 -1.0468 -0.9811 3122312 ChemDiv3_014470 CCc1ccc(NC(=O)N(Cc2ccco2)C3CCN(Cc4ccccc4)CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B17 compound treatment 0.259 0.0754 0.79 0.298 0.0639 0.76 1.101 0.9998 3038504 ChemDiv3_014471 CCc1ccc(NC(=O)CCCn2c(=O)c3cccn3c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B18 compound treatment 0.653 0.469 4.93 0.779 0.545 6.52 8.0964 0.9905 3122313 ChemDiv3_014472 Cc1ccc(NC(=O)Cn2c(SCc3cccc(c3)C(F)(F)F)nc4cccnc24)cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B19 compound treatment 0.335 0.151 1.59 0.423 0.189 2.26 2.7229 0.9852 3122314 ChemDiv3_014473 CC1CCC(CC1)NC(=O)C2CCCN2S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B20 compound treatment 0.113 -0.0706 -0.74 0.115 -0.119 -1.42 -1.5315 -0.9537 3038507 ChemDiv3_014474 CCc1cccc(Nc2ncnc3n4CCCCCc4nc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B21 compound treatment 0.327 0.143 1.51 0.374 0.14 1.67 2.249 0.9986 3122315 ChemDiv3_014475 Cc1ccc2c(CNCCc3ccco3)c(C(=O)O)n(Cc4ccccc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B22 compound treatment 0.501 0.317 3.33 0.572 0.338 4.04 5.2163 0.9954 3038510 ChemDiv3_014476 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)C4COc5ccccc5O4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B23 mock treatment 0.194 0.0104 0.11 0.258 0.0239 0.29 0.2799 0.9129 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 B24 mock treatment 0.186 0.00242 0.03 0.257 0.0229 0.27 0.212 0.7693 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C01 compound treatment 0.263 0.0794 0.83 0.286 0.0519 0.62 1.0292 0.9895 3122316 ChemDiv3_014477 CCNc1c(NC(=O)c2cccs2)c(=O)oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C02 compound treatment 0.051 -0.133 -1.39 0.053 -0.181 -2.17 -2.5164 -0.9772 3038514 ChemDiv3_014478 O=C(N1CCSC1=S)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C03 compound treatment 1.335 1.15 12.09 1.355 1.12 13.41 18.0343 0.9987 3122317 ChemDiv3_014479 CCOC(=O)c1c(C(=O)OCC)c2-c3ccccc3Cn2c1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C04 compound treatment 0.317 0.133 1.4 0.311 0.0769 0.92 1.6417 0.9792 3122318 ChemDiv3_014480 CS(=O)(=O)c1ncc(Cl)c(n1)C(=O)Nc2sc3CCCc3c2C(=O)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C05 compound treatment 0.172 -0.0116 -0.12 0.268 0.0339 0.41 0.2011 0.4745 3038518 ChemDiv3_014481 COc1ccc(NC(=O)c2ccc3oc(=O)c(cc3c2)S(=O)(=O)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C06 compound treatment 0.263 0.0794 0.83 0.358 0.124 1.48 1.6383 0.963 1673518 ChemDiv3_014482 COc1ccc(cc1)C(=O)COc2ccc3c(C)c(Cl)c(=O)oc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C07 compound treatment 0.37 0.186 1.96 0.43 0.196 2.34 3.0421 0.996 3122507 ChemDiv3_014483 Brc1cc(NCc2ccccc2)c3C(=O)c4ccccc4-c5onc1c53 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C08 compound treatment 0.127 -0.0566 -0.59 0.136 -0.0981 -1.17 -1.2498 -0.9503 3038557 ChemDiv3_014484 CC(N1CCn2c(C1)nc3cc(NC(=O)c4cccc(Br)c4)ccc23)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C09 compound treatment 0.338 0.154 1.62 0.411 0.177 2.12 2.6437 0.9913 3122508 ChemDiv3_014485 CSc1ccc(CCNCc2c(C(=O)O)n(Cc3ccc(C=C)cc3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C10 compound treatment 0.151 -0.0326 -0.34 0.157 -0.0771 -0.92 -0.8939 -0.909 3038560 ChemDiv3_014486 CC(C)c1ccc(cc1)N2CC(=O)C(=C2N)c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C11 compound treatment 0.185 0.00142 0.01 0.215 -0.0191 -0.23 -0.1507 -0.6595 3122509 ChemDiv3_014487 O=C(N1CCCCC1)c2cnn3c4CCCCCc4cnc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C12 compound treatment 0.828 0.644 6.77 0.903 0.669 8.0 10.4451 0.9965 1294026 ChemDiv3_014488 COc1ccc2oc3cc(C)nc(c4ccccc4)c3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C13 compound treatment 0.147 -0.0366 -0.38 0.175 -0.0591 -0.71 -0.7714 -0.959 3038564 ChemDiv3_014489 Cc1c(oc2ccc3OC4(CCCC4)C=Cc3c12)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C14 compound treatment 0.142 -0.0416 -0.44 0.187 -0.0471 -0.56 -0.707 -0.9921 3122510 ChemDiv3_014490 CC(Cc1ccccc1)Nc2nc3n(C)cnc3c(=N)n2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C15 compound treatment 0.144 -0.0396 -0.42 0.175 -0.0591 -0.71 -0.7936 -0.968 3122511 ChemDiv3_014491 CCN1CCCC1CNc2nc3ccc(Cl)cc3n4cnnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C16 compound treatment 0.219 0.0354 0.37 0.298 0.0639 0.76 0.8039 0.9451 3122512 ChemDiv3_014492 Cc1ccc2oc(cc(=O)c2c1)C(=O)Nc3ccc(C)c(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C17 compound treatment 0.338 0.154 1.62 0.43 0.196 2.34 2.8044 0.9838 3038603 ChemDiv3_014493 Cc1n(CC(=O)Nc2ccc(C)cc2)c(C)c3c(=O)n(ncc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C18 compound treatment 0.253 0.0694 0.73 0.365 0.131 1.57 1.6233 0.9394 3122513 ChemDiv3_014494 O=C([C@@H]1[C@@H]2C[C@@H]3OC(=O)[C@H]1[C@@H]3C2)N(Cc4ccccc4)Cc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C19 compound treatment 0.113 -0.0706 -0.74 0.147 -0.0871 -1.04 -1.2607 -0.9861 3038606 ChemDiv3_014495 Cc1nnc2sc(SCc3ccccc3)nn2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C20 compound treatment 0.217 0.0334 0.35 0.267 0.0329 0.39 0.5268 0.9983 3122514 ChemDiv3_014496 CC(C)C(=O)/N=C/1\SC2CS(=O)(=O)CC2N1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C21 compound treatment 0.244 0.0604 0.63 0.328 0.0939 1.12 1.2434 0.9634 3038609 ChemDiv3_014497 Oc1nc2ccccc2cc1CN(C3CCCCC3)C(=O)c4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C22 compound treatment 0.546 0.362 3.81 0.619 0.385 4.61 5.9481 0.9955 3122515 ChemDiv3_014498 CCc1cc(=O)oc2cc3occ(c3cc12)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C23 mock treatment 0.308 0.124 1.31 0.327 0.0929 1.11 1.7102 0.9968 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 C24 mock treatment 0.178 -0.00558 -0.06 0.246 0.0119 0.14 0.0595 0.3857 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D01 compound treatment 0.245 0.0614 0.65 0.285 0.0509 0.61 0.8871 0.9996 3038612 ChemDiv3_014499 COc1ccc(cc1)c2coc3cc4oc(=O)c(CC(=O)O)c(C)c4cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D02 compound treatment 0.588 0.404 4.25 0.68 0.446 5.34 6.7761 0.9936 3122516 ChemDiv3_014500 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D03 compound treatment 0.149 -0.0346 -0.36 0.153 -0.0811 -0.97 -0.9426 -0.9102 3122517 ChemDiv3_014501 COc1cccc(CN2COc3ccc4c5ccccc5c(=O)oc4c3C2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D04 compound treatment 0.166 -0.0176 -0.18 0.23 -0.00406 -0.05 -0.1649 -0.8639 3038616 ChemDiv3_014502 Cc1scc(CN2CCOCC2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D05 compound treatment 0.315 0.131 1.38 0.402 0.168 2.01 2.3967 0.9832 3038651 ChemDiv3_014503 COCc1cc(C)nc2sc3C(=O)NC4(CCCCC4)Nc3c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D06 compound treatment 0.244 0.0604 0.63 0.355 0.121 1.45 1.4718 0.9316 3038655 ChemDiv3_014504 OC(=O)C1=Cc2sc3CCCCc3c2CS1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D07 compound treatment 0.07 -0.114 -1.19 0.079 -0.155 -1.86 -2.1554 -0.9772 3122518 ChemDiv3_014505 CC(C)N(Cc1cccs1)Cc2cc(=O)oc3cc(C)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D08 compound treatment 0.19 0.00642 0.07 0.308 0.0739 0.88 0.6732 0.7588 3038657 ChemDiv3_014506 CSc1ncc(C(=O)O)c(n1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D09 compound treatment 0.22 0.0364 0.38 0.273 0.0389 0.47 0.5999 0.9952 3122519 ChemDiv3_014507 CN(C(=O)c1cccc(NC(=O)[C@H]2[C@H]3C[C@H]4OC(=O)[C@@H]2[C@H]4C3)c1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D10 compound treatment 0.655 0.471 4.95 0.752 0.518 6.2 7.8828 0.9938 3122520 ChemDiv3_014508 CC1CCCC(C1C)N(Cc2ccco2)C(=O)NCc3noc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D11 compound treatment 0.461 0.277 2.91 0.597 0.363 4.34 5.1307 0.9812 3038663 ChemDiv3_014509 O=c1[nH]c(nc2Oc3ccccc3Cc21)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D12 compound treatment 0.212 0.0284 0.3 0.313 0.0789 0.94 0.8789 0.8873 3122521 ChemDiv3_014510 Nc1c(nnn1c2cccc(c2)C(F)(F)F)c3nc(no3)c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D13 compound treatment 0.209 0.0254 0.27 0.239 0.00494 0.06 0.2305 0.8431 3038665 ChemDiv3_014511 CCOc1ccccc1NC(=O)CSc2nc3nccnc3c(=O)n2Cc4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D14 compound treatment 0.343 0.159 1.67 0.465 0.231 2.76 3.1377 0.9712 3122522 ChemDiv3_014512 CC1Cn2cc(C(=O)Nc3cccc(F)c3)c(=O)c4c(Cl)ccc(O1)c24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D15 compound treatment 0.106 -0.0776 -0.81 0.107 -0.127 -1.52 -1.6511 -0.9573 3122523 ChemDiv3_014513 CC1CN(CCCNc2nnc3c4ccccc4n(C)c3n2)CCN1c5cccc(C)c5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D16 compound treatment 0.22 0.0364 0.38 0.285 0.0509 0.61 0.7014 0.9748 3038700 ChemDiv3_014514 CCN1CCC(CC1)N(Cc2ccco2)C(=O)Nc3cc(C)cc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D17 compound treatment 0.266 0.0824 0.87 0.33 0.0959 1.15 1.4237 0.9903 3122524 ChemDiv3_014515 CC(C)NC(=O)CCCn1c(=O)c2cccn2c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D18 compound treatment 0.309 0.125 1.32 0.379 0.145 1.73 2.1576 0.9908 3122525 ChemDiv3_014516 CC(NC(=O)c1ccc(cc1)n2c(C)cc3CCCCc32)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D19 compound treatment 0.209 0.0254 0.27 0.262 0.0279 0.33 0.4251 0.9938 3038706 ChemDiv3_014517 Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D20 compound treatment 0.126 -0.0576 -0.6 0.135 -0.0991 -1.19 -1.2657 -0.9512 3122526 ChemDiv3_014518 Cc1ccc(CNc2ncnc3n4CCCCCc4nc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D21 compound treatment 0.113 -0.0706 -0.74 0.139 -0.0951 -1.14 -1.3284 -0.9785 3038709 ChemDiv3_014519 CN(Cc1ccccc1)C(=O)Cn2c(=O)c3cccn3c4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D22 compound treatment 0.242 0.0584 0.61 0.269 0.0349 0.42 0.7294 0.9825 3122527 ChemDiv3_014520 Cc1cc(Nc2cccc(Cl)c2)nc3ccc(NC(=O)c4ccccn4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D23 mock treatment 0.19 0.00642 0.07 0.256 0.0219 0.26 0.2333 0.8608 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 D24 mock treatment 0.179 -0.00458 -0.05 0.24 0.00594 0.07 0.0162 0.1888 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E01 compound treatment 0.245 0.0614 0.65 0.303 0.0689 0.82 1.0393 0.9926 3038712 ChemDiv3_014521 CCNc1c(NS(=O)(=O)CC)c(=O)oc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E02 compound treatment 0.205 0.0214 0.22 0.28 0.0459 0.55 0.5477 0.9223 3122528 ChemDiv3_014522 CC1(C)N=C(Nc2ccccc2)SC1=N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E03 compound treatment 0.293 0.109 1.15 0.346 0.112 1.34 1.7596 0.9971 3122529 ChemDiv3_014523 CCOC(=O)C1=C(Cn2ccnc2)NC(=O)NC1c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E04 compound treatment 0.218 0.0344 0.36 0.313 0.0789 0.94 0.9234 0.9132 3122530 ChemDiv3_014524 CN(Cc1ccccc1)S(=O)(=O)c2ccc(NC(=O)c3nc(ncc3Cl)S(=O)(=O)C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E05 compound treatment 0.595 0.411 4.32 0.635 0.401 4.8 6.4474 0.9986 3122531 ChemDiv3_014525 Cc1c(C2CCN(CC2)S(=O)(=O)c3ccc(C)c(C)c3)c4ccccc4n1CC(=O)N5CCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E06 compound treatment 0.222 0.0384 0.4 0.256 0.0219 0.26 0.4709 0.9783 3037862 ChemDiv3_014526 COc1ccc(cc1)C2CC(=NCCN2Cc3cccc(C)c3)c4c(O)c5ccccc5oc4=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E07 compound treatment 0.232 0.0484 0.51 0.343 0.109 1.3 1.2812 0.9158 3122532 ChemDiv3_014527 CC1CCN(CC1)c2cc(N(C)C)c3noc4-c5ccccc5C(=O)c2c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E08 compound treatment 0.254 0.0704 0.74 0.356 0.122 1.46 1.5546 0.9504 3037865 ChemDiv3_014528 CC(=O)N(Cc1nnc2c3ccccc3c(C)nn12)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E09 compound treatment 0.315 0.131 1.38 0.443 0.209 2.5 2.7436 0.9608 3122533 ChemDiv3_014529 Cc1ccc(cc1C)C(=O)c2cnc3cc4OCOc4cc3c2S(=O)(=O)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E10 compound treatment 0.076 -0.108 -1.13 0.089 -0.145 -1.74 -2.0262 -0.9784 3122715 ChemDiv3_014530 CC(N1CC(=O)C(=C1N)c2nc3ccccc3[nH]2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E11 compound treatment 0.141 -0.0426 -0.45 0.175 -0.0591 -0.71 -0.8159 -0.9756 3037870 ChemDiv3_014531 C(NCc1c[nH]nc1c2ccccc2)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E12 compound treatment 0.266 0.0824 0.87 0.396 0.162 1.94 1.9821 0.934 3122716 ChemDiv3_014532 CN(C)Cc1c(C)n(Cc2ccccc2)c3C(=O)c4ccc(Br)cc4-c13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E13 compound treatment 0.254 0.0704 0.74 0.244 0.00994 0.12 0.607 0.8104 3037873 ChemDiv3_014533 OC(=O)C1CCCN(C1)c2ncnc3c2sc4cccc(F)c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E14 compound treatment 0.339 0.155 1.63 0.418 0.184 2.2 2.7103 0.9892 1603379 ChemDiv3_014534 Cc1ccc(cc1)C(N(Cc2ccco2)C(=O)Cn3nnc4ccccc34)C(=O)NCc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E15 compound treatment 0.161 -0.0226 -0.24 0.192 -0.0421 -0.5 -0.5236 -0.9411 3122717 ChemDiv3_014535 O=C(NCc1ccco1)c2ccc(Cn3c(SCc4ccccc4)nc5ccncc35)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E16 compound treatment 0.222 0.0384 0.4 0.303 0.0689 0.82 0.8685 0.9459 3037909 ChemDiv3_014536 OC(=O)CNC(=O)C(O)(c1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E17 compound treatment 0.255 0.0714 0.75 0.351 0.117 1.4 1.5197 0.9573 3122718 ChemDiv3_014537 COc1ccc2C3CC(C)(NC(=O)C3S(=O)(=O)c4ccccc4)Oc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E18 compound treatment 0.322 0.138 1.45 0.433 0.199 2.38 2.711 0.972 3122719 ChemDiv3_014538 O=C([C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)N4CCCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E19 compound treatment 1.039 0.855 8.98 1.162 0.928 11.1 14.2032 0.9945 3037913 ChemDiv3_014539 CC(C)C(=O)Oc1cc(c2ccccc2)c3oc(=O)sc3c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E20 compound treatment 0.233 0.0494 0.52 0.302 0.0679 0.81 0.9418 0.9765 3122720 ChemDiv3_014540 COc1ccc(cc1)N/2C3CS(=O)(=O)CC3S\C2=N/C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E21 compound treatment 0.137 -0.0466 -0.49 0.176 -0.0581 -0.69 -0.8372 -0.9853 3037915 ChemDiv3_014541 CC(=O)Nc1ccc2n3CCN(Cc3nc2c1)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E22 compound treatment 0.611 0.427 4.49 0.684 0.45 5.38 6.9808 0.9959 1430336 ChemDiv3_014542 CCc1c(C)c2cc3c(C)coc3cc2oc1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E23 mock treatment 0.168 -0.0156 -0.16 0.18 -0.0541 -0.65 -0.5731 -0.8589 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 E24 mock treatment 0.18 -0.00358 -0.04 0.26 0.0259 0.31 0.1928 0.6169 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F01 compound treatment 0.442 0.258 2.71 0.499 0.265 3.17 4.1605 0.997 3037919 ChemDiv3_014543 Cc1c(CC(=O)O)c(=O)oc2cc3oc4CCCCc4c3cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F02 compound treatment 0.236 0.0524 0.55 0.373 0.139 1.66 1.5647 0.8936 3037970 ChemDiv3_014544 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F03 compound treatment 0.218 0.0344 0.36 0.291 0.0569 0.68 0.7373 0.9561 3122721 ChemDiv3_014545 COC(=O)Cc1c(C)c2ccc3OCN(Cc4cccc(OC)c4)Cc3c2oc1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F04 compound treatment 0.089 -0.0946 -0.99 0.118 -0.116 -1.39 -1.6843 -0.9865 3037976 ChemDiv3_014546 Cc1scc(CN2CCC3(CC2)OCCO3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F05 compound treatment 0.227 0.0434 0.46 0.306 0.0719 0.86 0.931 0.9559 3122722 ChemDiv3_014547 Cc1cc(NCC=C)n2cnnc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F06 compound treatment 0.236 0.0524 0.55 0.35 0.116 1.39 1.3701 0.9181 3037979 ChemDiv3_014548 Cc1sc2C=C(SCc2c1C)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F07 compound treatment 0.204 0.0204 0.21 0.3 0.0659 0.79 0.7095 0.8678 3122723 ChemDiv3_014549 COc1ccc2oc(=O)cc(CN3CCN(CC3)c4ncccn4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F08 compound treatment 0.247 0.0634 0.67 0.355 0.121 1.45 1.4941 0.938 3037982 ChemDiv3_014550 CSc1nc(nc2Oc3c(C)ncc(CO)c3Cc12)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F09 compound treatment 0.277 0.0934 0.98 0.383 0.149 1.78 1.9538 0.9605 3122724 ChemDiv3_014551 O=C(Nc1nnc(s1)N2CCCCC2)NC3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F10 compound treatment 0.805 0.621 6.53 0.863 0.629 7.52 9.9359 0.9975 3122725 ChemDiv3_014552 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N(CC=C)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F11 compound treatment 0.527 0.343 3.61 0.642 0.408 4.88 6.0016 0.9889 3037986 ChemDiv3_014553 Cn1nc(C(=O)NCc2ccco2)c3CSc4ccccc4-c31 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F12 compound treatment 0.262 0.0784 0.82 0.34 0.106 1.27 1.4786 0.9782 3122726 ChemDiv3_014554 Cc1ccc(Cl)cc1n2nnc(c2N)c3nc(no3)c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F13 compound treatment 0.231 0.0474 0.5 0.355 0.121 1.45 1.3753 0.8987 3038036 ChemDiv3_014555 CCn1c2ccccc2c3nnc(nc13)N4CCC(CC4)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F14 compound treatment 0.12 -0.0636 -0.67 0.143 -0.0911 -1.09 -1.2426 -0.9724 3122727 ChemDiv3_014556 O=C(NC1(CC2CC3CC(C2)C1)C3)N4CCC(CN5CCCCC5)CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F15 compound treatment 0.378 0.194 2.04 0.491 0.257 3.07 3.6176 0.9802 3038040 ChemDiv3_014557 FC(F)(F)c1cccc(Cn2ccn(c3cccc(Cl)c3)c(=O)c2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F16 compound treatment 0.18 -0.00358 -0.04 0.297 0.0629 0.75 0.5059 0.671 3122728 ChemDiv3_014558 CCN1CCC(CC1)N(Cc2ccco2)C(=O)Nc3cccc(c3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F17 compound treatment 0.319 0.135 1.42 0.401 0.167 2.0 2.418 0.9862 3122729 ChemDiv3_014559 CC(NC(=O)CCCn1c(=O)c2cccn2c3ccccc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F18 compound treatment 0.411 0.227 2.39 0.502 0.268 3.21 3.9557 0.9895 3038047 ChemDiv3_014560 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F19 compound treatment 0.327 0.143 1.51 0.414 0.18 2.15 2.5874 0.9847 3122730 ChemDiv3_014561 O=C(NCc1ccccc1)C2CCCN(C2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F20 compound treatment 0.161 -0.0226 -0.24 0.191 -0.0431 -0.52 -0.532 -0.938 3038050 ChemDiv3_014562 C(Cc1ccsc1)Nc2ncnc3n4CCCCCc4nc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F21 compound treatment 0.228 0.0444 0.47 0.303 0.0689 0.82 0.9131 0.9636 3122731 ChemDiv3_014563 CNC(=O)Cn1c(=O)c2cccn2c3cccnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F22 compound treatment 0.357 0.173 1.82 0.414 0.18 2.15 2.8102 0.9965 3038054 ChemDiv3_014564 CCc1nnc(NC(=O)c2nc(c3ccc(Cl)cc3)n4CCCCCc24)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F23 mock treatment 0.3 0.116 1.22 0.39 0.156 1.87 2.1838 0.979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 F24 mock treatment 0.164 -0.0196 -0.21 0.222 -0.0121 -0.14 -0.2475 -0.985 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G01 compound treatment 0.214 0.0304 0.32 0.273 0.0389 0.47 0.5553 0.9831 3122732 ChemDiv3_014565 CCn1c(=O)c(O)nc2c(=O)oc3ccccc3c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G02 compound treatment 0.167 -0.0166 -0.17 0.186 -0.0481 -0.58 -0.5298 -0.8817 3122733 ChemDiv3_014566 Clc1ccc(OCc2nc3c4cnn(c5ccc(Cl)cc5)c4ncn3n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G03 compound treatment 0.226 0.0424 0.45 0.247 0.0129 0.15 0.4245 0.9 3040359 ChemDiv3_014567 CCC(C)NS(=O)(=O)c1ccc2NC(=O)Cc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G04 compound treatment 0.045 -0.139 -1.46 0.065 -0.169 -2.02 -2.4595 -0.987 3040360 ChemDiv3_014568 CSc1ncc(Cl)c(n1)C(=O)Oc2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G05 compound treatment 0.237 0.0534 0.56 0.324 0.0899 1.08 1.1576 0.9539 3040361 ChemDiv3_014569 C1CN2C(N2C1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G06 compound treatment 1.359 1.18 12.35 1.348 1.11 13.33 18.1533 0.9993 3040362 ChemDiv3_014570 Clc1ccc(CN(Cc2ccco2)C(=O)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G07 compound treatment 0.284 0.1 1.05 0.351 0.117 1.4 1.7351 0.9903 3040363 ChemDiv3_014571 COc1ccc(cc1OC)C2=NOC(C2)C(=O)N3CC4(C)CC3CC(C)(C)C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G08 compound treatment 0.259 0.0754 0.79 0.319 0.0849 1.02 1.2787 0.9924 3040364 ChemDiv3_014572 Cc1nn2c(CN(C(=O)c3ccccc3)c4ccccc4)nnc2c5ccccc15 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G09 compound treatment 0.722 0.538 5.65 0.78 0.546 6.53 8.6173 0.9974 3040365 ChemDiv3_014573 CCc1ccc(cc1)S(=O)(=O)c2c(cnc3cc4OCCOc4cc23)C(=O)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G10 compound treatment 0.21 0.0264 0.28 0.276 0.0419 0.5 0.551 0.961 3122734 ChemDiv3_014574 NC1=C(C(=O)CN1CC=C)c2nc3ccccc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G11 compound treatment 0.432 0.248 2.61 0.597 0.363 4.34 4.9154 0.9703 3122735 ChemDiv3_014575 O=C(NCc1ccccc1)c2cc(c(s2)N3CCOCC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G12 compound treatment 0.244 0.0604 0.63 0.317 0.0829 0.99 1.1504 0.9767 3040366 ChemDiv3_014576 Nc1c2CCCCCc2nc3ccn(c4ccccc4)c(=O)c13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G13 compound treatment 0.415 0.231 2.43 0.518 0.284 3.4 4.1208 0.9865 3122736 ChemDiv3_014577 CCC(C(=O)O)n1nc(C)c2sc3ccccc3c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G14 compound treatment 1.364 1.18 12.4 1.375 1.14 13.65 18.4189 0.9988 1735091 ChemDiv3_014578 CCC(=O)c1c(C)nc2n(Cc3ccccc3)c4ccccc4n12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G15 compound treatment 0.169 -0.0146 -0.15 0.214 -0.0201 -0.24 -0.278 -0.9764 3122737 ChemDiv3_014579 Cc1c(CNC2CCCC2)c(C(=O)O)c(C)n1Cc3ccccc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G16 compound treatment 0.432 0.248 2.61 0.498 0.264 3.16 4.0778 0.9955 3122738 ChemDiv3_014580 CCOc1ccc(cc1OCC)c2nonc2NC(=O)c3oc4cc(C)c(Cl)cc4c3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G17 compound treatment 0.374 0.19 2.0 0.505 0.271 3.24 3.7063 0.9731 3040367 ChemDiv3_014581 CC(C)c1ccc(cc1)S(=O)(=O)C2C3CC(C)(Oc4ccccc34)N(C)C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G18 compound treatment 0.271 0.0874 0.92 0.313 0.0789 0.94 1.317 0.9999 3122739 ChemDiv3_014582 CN(C(=O)[C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G19 compound treatment 0.323 0.139 1.46 0.389 0.155 1.85 2.3462 0.9932 3040368 ChemDiv3_014583 Cc1ccc2occ(CC(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G20 compound treatment 0.318 0.134 1.41 0.432 0.198 2.37 2.6728 0.9694 3122740 ChemDiv3_014584 CCc1cc(=O)oc2cc(C)c3c(coc3c12)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G21 compound treatment 0.227 0.0434 0.46 0.296 0.0619 0.74 0.8464 0.9728 3040369 ChemDiv3_014585 CN(Cc1nc2ccccc2n1C)C(=O)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G22 compound treatment 0.636 0.452 4.75 0.751 0.517 6.18 7.7332 0.9915 3122741 ChemDiv3_014586 CCc1c(C)c2cc3c(coc3cc2oc1=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G23 mock treatment 0.18 -0.00358 -0.04 0.168 -0.0661 -0.79 -0.5855 -0.7399 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 G24 mock treatment 0.168 -0.0156 -0.16 0.198 -0.0361 -0.43 -0.4208 -0.9119 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H01 compound treatment 0.265 0.0814 0.86 0.291 0.0569 0.68 1.0863 0.9937 1263075 ChemDiv3_014587 O=c1oc2cc3occ(c4ccccc4)c3cc2c5CCCc51 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H02 compound treatment 0.628 0.444 4.67 0.623 0.389 4.65 6.5909 1.0 3040370 ChemDiv3_014588 COc1ccc(CCNC(=O)c2ccc(Cl)cc2NC(=O)C3=C(C)OCCS3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H03 compound treatment 0.157 -0.0266 -0.28 0.218 -0.0161 -0.19 -0.3333 -0.9834 3122916 ChemDiv3_014589 CCCCc1cc(=O)oc2c3CN(Cc4ccc(OC)c(OC)c4)COc3c(Cl)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H04 compound treatment 0.203 0.0194 0.2 0.278 0.0439 0.53 0.5159 0.915 3040371 ChemDiv3_014590 CCN1CCN(Cc2csc(C)c2C)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H05 compound treatment 0.778 0.594 6.24 0.784 0.55 6.58 9.067 0.9997 3122917 ChemDiv3_014591 FC(F)(F)c1cccc(c1)n2cnnn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H06 compound treatment 0.183 -5.81E-4 -0.01 0.292 0.0579 0.69 0.4858 0.7009 3040372 ChemDiv3_014592 Cc1scc(CSCC(=O)O)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H07 compound treatment 0.497 0.313 3.29 0.483 0.249 2.98 4.4336 0.9988 3122918 ChemDiv3_014593 CCOc1ccc(cc1)N(C)Cc2cc(=O)oc3ccc(OC)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H08 compound treatment 0.397 0.213 2.24 0.524 0.29 3.47 4.0379 0.9777 3122919 ChemDiv3_014594 O=c1n(Cc2ccccc2)c(=O)c3oc4ccccc4c3n1Cc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H09 compound treatment 0.318 0.134 1.41 0.37 0.136 1.63 2.1483 0.9975 3040373 ChemDiv3_014595 CCc1ccccc1NC(=O)NCc2c(sc3CCCCc23)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H10 compound treatment 0.349 0.165 1.74 0.473 0.239 2.86 3.2499 0.9715 3122920 ChemDiv3_014596 CSc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H11 compound treatment 0.302 0.118 1.24 0.368 0.134 1.6 2.0126 0.9921 3040374 ChemDiv3_014597 Cn1nc(C(=O)N(Cc2ccco2)C3CCCCC3)c4CSc5ccccc5-c41 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H12 compound treatment 0.3 0.116 1.22 0.401 0.167 2.0 2.2769 0.9723 3122921 ChemDiv3_014598 Cn1c(=O)c2sccc2n3c(CCCC(=O)Nc4ccccc4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H13 compound treatment 0.383 0.199 2.09 0.462 0.228 2.73 3.4094 0.9915 3122922 ChemDiv3_014599 CCn1c2ccccc2c3nnc(nc13)N4CCc5ccccc5C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H14 compound treatment 0.518 0.334 3.51 0.655 0.421 5.04 6.0447 0.9845 3040375 ChemDiv3_014600 CCCN(CCC)C(=O)CSc1nnc(c2cc3sccc3n2C)n1c4c(C)cc(C)cc4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H15 compound treatment 0.801 0.617 6.48 0.827 0.593 7.09 9.6016 0.999 3122923 ChemDiv3_014601 O=C(NCCOC1(CC2CC3CC(C2)C1)C3)c4nc(no4)c5cccnc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H16 compound treatment 0.301 0.117 1.23 0.506 0.272 3.25 3.1726 0.9118 3122924 ChemDiv3_014602 CCN1CCC(CC1)N(Cc2cccc(OC)c2)C(=O)NC3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H17 compound treatment 0.276 0.0924 0.97 0.405 0.171 2.05 2.1325 0.942 3040376 ChemDiv3_014603 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H18 compound treatment 0.523 0.339 3.56 0.641 0.407 4.87 5.9634 0.9883 3122925 ChemDiv3_014604 CCOC(=O)c1cc(C)n(c1C)c2ccc(cc2)C(=O)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H19 compound treatment 0.782 0.598 6.28 0.877 0.643 7.69 9.8835 0.995 3040377 ChemDiv3_014605 CCC(Sc1nncn2c3ccsc3cc12)C(=O)Nc4ccccc4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H20 compound treatment 0.397 0.213 2.24 0.479 0.245 2.93 3.6571 0.9912 3122926 ChemDiv3_014606 CC(Sc1ncc(c(N)n1)S(=O)(=O)c2ccccc2)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H21 compound treatment 0.28 0.0964 1.01 0.385 0.151 1.81 1.993 0.9626 3122927 ChemDiv3_014607 CN(Cc1ccccc1)C(=O)CCCn2c(=O)c3cccn3c4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H22 compound treatment 0.301 0.117 1.23 0.337 0.103 1.23 1.7429 1.0 3040378 ChemDiv3_014608 Cc1sc2C=C(SCc2c1C)C(=O)Nc3cccc(C)c3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H23 mock treatment 0.21 0.0264 0.28 0.271 0.0369 0.44 0.5087 0.9749 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 H24 mock treatment 0.152 -0.0316 -0.33 0.195 -0.0391 -0.47 -0.565 -0.9859 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I01 compound treatment 0.557 0.373 3.92 0.617 0.383 4.58 6.0129 0.997 3122928 ChemDiv3_014609 COC(=O)c1nnn(c1C(=O)OC)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I02 compound treatment 0.256 0.0724 0.76 0.277 0.0429 0.51 0.9011 0.9817 3040379 ChemDiv3_014610 Clc1ccc(cc1)n2ncc3c4nc(nn4cnc23)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I03 compound treatment 0.262 0.0784 0.82 0.25 0.0159 0.19 0.7172 0.8484 3122929 ChemDiv3_014611 O=C1Cc2cc(ccc2N1)S(=O)(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I04 compound treatment 0.388 0.204 2.15 0.518 0.284 3.4 3.9203 0.9755 3122930 ChemDiv3_014612 CCOC(=O)Cn1c2SC3C4CCC(C4)C3C(c2sc1=O)c5ccc(Cl)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I05 compound treatment 0.068 -0.116 -1.21 0.066 -0.168 -2.01 -2.2802 -0.9708 3040380 ChemDiv3_014613 CCOc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccc(F)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I06 compound treatment 1.352 1.17 12.27 1.346 1.11 13.3 18.0844 0.9992 3122931 ChemDiv3_014614 Cc1ccc(CN(Cc2ccco2)C(=O)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I07 compound treatment 0.257 0.0734 0.77 0.368 0.134 1.6 1.6784 0.9438 3122932 ChemDiv3_014615 COc1cccc2Cc3c(SCC(=O)N(C)c4ccccc4)nc(nc3Oc12)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I08 compound treatment 0.301 0.117 1.23 0.395 0.161 1.93 2.2336 0.9768 3040381 ChemDiv3_014616 CCCCN1C(c2c(n[nH]c2C1=O)c3ccccc3O)c4cccc(O)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I09 compound treatment 0.442 0.258 2.71 0.501 0.267 3.19 4.1775 0.9967 3122933 ChemDiv3_014617 CCOc1ccc(cc1)S(=O)(=O)c2c(cnc3ccc(F)cc23)C(=O)c4ccc(C)c(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I10 compound treatment 0.118 -0.0656 -0.69 0.128 -0.106 -1.27 -1.3844 -0.9588 3040382 ChemDiv3_014618 NC1=C(C(=O)CN1C2CCCCCC2)c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I11 compound treatment 0.23 0.0464 0.49 0.324 0.0899 1.08 1.1056 0.9359 3122934 ChemDiv3_014619 OC(=O)c1cnn(c1n2cccc2CNCc3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I12 compound treatment 0.181 -0.00258 -0.03 0.261 0.0269 0.32 0.2087 0.6454 3040383 ChemDiv3_014620 COc1ccc2n3CCN=C(N(C)C)c3c(C#N)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I13 compound treatment 0.42 0.236 2.48 0.5 0.266 3.18 4.0056 0.9925 3122935 ChemDiv3_014621 Brc1ccc(cc1)S(=O)Cc2ccc(o2)C(=O)NC3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I14 compound treatment 0.308 0.124 1.31 0.405 0.171 2.05 2.3701 0.9766 1505736 ChemDiv3_014622 CCN(CC)CCn1c2nc(c(C(=O)CC)n2c3ccccc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I15 compound treatment 0.225 0.0414 0.44 0.294 0.0599 0.72 0.8147 0.9713 3122936 ChemDiv3_014623 Cc1c(CNCCc2c[nH]c3ccccc23)c(C(=O)O)c(C)n1Cc4ccc(F)cc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I16 compound treatment 0.308 0.124 1.31 0.386 0.152 1.82 2.2094 0.9869 3122937 ChemDiv3_014624 CCCCC1CCC(CC1)C(=O)Nc2nonc2c3ccc(OCC)c(OCC)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I17 compound treatment 0.328 0.144 1.52 0.469 0.235 2.81 3.0601 0.9581 3040384 ChemDiv3_014625 CCc1ccccc1N2CC(CC2=O)c3nc4ccccc4n3CCc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I18 compound treatment 0.268 0.0844 0.89 0.354 0.12 1.43 1.6416 0.9732 3122938 ChemDiv3_014626 O=C([C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I19 compound treatment 0.678 0.494 5.19 0.71 0.476 5.69 7.6983 0.9989 3040385 ChemDiv3_014627 CC(C)COC(=O)c1sc(NC(=O)Cc2coc3cc(C)cc(C)c23)nc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I20 compound treatment 0.313 0.129 1.36 0.529 0.295 3.53 3.4563 0.914 3122939 ChemDiv3_014628 Cc1ccc(cc1)S(=O)(=O)N(CC=C)c2nccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I21 compound treatment 0.279 0.0954 1.0 0.308 0.0739 0.88 1.3341 0.9981 3122940 ChemDiv3_014629 COc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nc3nc4CCCCc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I22 compound treatment 0.072 -0.112 -1.17 0.067 -0.167 -2.0 -2.242 -0.9676 3040386 ChemDiv3_014630 Cc1c(CCC(=O)O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I23 mock treatment 0.197 0.0134 0.14 0.217 -0.0171 -0.2 -0.0447 -0.1802 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 I24 mock treatment 0.19 0.00642 0.07 0.228 -0.00606 -0.07 -0.0036 -0.0367 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J01 compound treatment 0.305 0.121 1.28 0.408 0.174 2.08 2.3732 0.9724 3122941 ChemDiv3_014631 Cc1c2occ(c2cc3c4CCCCc4c(=O)oc13)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J02 compound treatment 0.388 0.204 2.15 0.458 0.224 2.68 3.4126 0.994 3122942 ChemDiv3_014632 CC(C)Oc1ccc(CNC(=O)c2ccc(Cl)cc2NC(=O)C3=C(C)OCCS3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J03 compound treatment 0.091 -0.0926 -0.97 0.131 -0.103 -1.23 -1.5595 -0.9931 3040387 ChemDiv3_014633 CCc1cc(=O)oc2c(C)c3OCN(Cc4ccccc4)Cc3cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J04 compound treatment 0.094 -0.0896 -0.94 0.115 -0.119 -1.42 -1.6726 -0.9797 3040388 ChemDiv3_014634 Cc1cc(CN2CCc3ccccc3C2)cs1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J05 compound treatment 0.482 0.298 3.13 1.047 0.813 9.73 9.0938 0.8899 3122943 ChemDiv3_014635 Cc1cccc(c1)n2nnc(n2)c3ccc(cc3)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J06 compound treatment 0.273 0.0894 0.94 0.297 0.0629 0.75 1.1965 0.994 3040389 ChemDiv3_014636 CC(C)NC(=O)CSCc1csc2CCCCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J07 compound treatment 0.743 0.559 5.88 0.755 0.521 6.23 8.5617 0.9996 3123121 ChemDiv3_014637 COc1ccc2oc(=O)cc(CN(C)c3c(C)cc(C)cc3C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J08 compound treatment 0.279 0.0954 1.0 0.358 0.124 1.48 1.7571 0.9818 3123122 ChemDiv3_014638 CCc1ccc(NC(=O)Cn2c(=O)n(C(C)C)c(=O)c3oc4ccccc4c23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J09 compound treatment 0.734 0.55 5.78 0.758 0.524 6.27 8.5203 0.9992 3040390 ChemDiv3_014639 CCc1ccc(CN(Cc2c[nH]nc2c3ccc(OC)cc3)C(=O)Nc4ccc5OCCOc5c4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J10 compound treatment 0.275 0.0914 0.96 0.332 0.0979 1.17 1.5075 0.9951 3123123 ChemDiv3_014640 CCc1ccccc1NC(=O)CCNS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J11 compound treatment 0.566 0.382 4.02 0.671 0.437 5.23 6.5366 0.9915 3040391 ChemDiv3_014641 CC(=O)Nc1nn2c(nnc2s1)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J12 compound treatment 0.25 0.0664 0.7 0.325 0.0909 1.09 1.2626 0.9769 3123124 ChemDiv3_014642 CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J13 compound treatment 0.278 0.0944 0.99 0.408 0.174 2.08 2.1727 0.9425 3123125 ChemDiv3_014643 CCN(CCCNc1nnc2c3ccccc3n(CC)c2n1)c4cccc(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J14 compound treatment 0.513 0.329 3.46 0.642 0.408 4.88 5.8976 0.9858 3040443 ChemDiv3_014644 Cc1ccc(C)c(c1)n2c(SCc3ccc(C#N)cc3)nnc2c4cc5sccc5n4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J15 compound treatment 0.267 0.0834 0.88 0.347 0.113 1.35 1.575 0.978 3040444 ChemDiv3_014645 CC1CCCCN1S(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J16 compound treatment 0.272 0.0884 0.93 0.375 0.141 1.69 1.849 0.9605 3040445 ChemDiv3_014646 CCN1CCC(CC1)N(Cc2ccc(F)cc2)C(=O)NC3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J17 compound treatment 0.261 0.0774 0.81 0.329 0.0949 1.14 1.3781 0.9866 3040446 ChemDiv3_014647 CN(C1CCCCC1)S(=O)(=O)c2cc3OCC(=O)Nc3cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J18 compound treatment 0.122 -0.0616 -0.65 0.133 -0.101 -1.21 -1.3123 -0.957 3040447 ChemDiv3_014648 CCOc1ccc(CCNc2ncnc3n4CCCCCc4nc23)cc1OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J19 compound treatment 0.246 0.0624 0.66 0.322 0.0879 1.05 1.2075 0.9741 3040448 ChemDiv3_014649 CCCNC(=O)C1CCCN(C1)S(=O)(=O)N2CCC3(CC2)OCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J20 compound treatment 0.339 0.155 1.63 0.425 0.191 2.28 2.7696 0.9864 3123126 ChemDiv3_014650 CCc1ccc(NC(=O)CSc2ncc(c(N)n2)S(=O)(=O)c3ccc(cc3)C(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J21 compound treatment 1.278 1.09 11.49 1.163 0.929 11.11 15.9866 0.9999 3123127 ChemDiv3_014651 Fc1ccccc1NC(=O)CCCn2c(=O)c3cccn3c4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J22 compound treatment 0.247 0.0634 0.67 0.334 0.0999 1.2 1.3165 0.9618 3040449 ChemDiv3_014652 COc1ccc(CNC(=O)C2=Cc3sc(C)c(C)c3CS2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J23 mock treatment 0.242 0.0584 0.61 0.334 0.0999 1.2 1.2793 0.9519 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 J24 mock treatment 0.169 -0.0146 -0.15 0.215 -0.0191 -0.23 -0.2696 -0.9812 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K01 compound treatment 0.227 0.0434 0.46 0.298 0.0639 0.76 0.8634 0.9694 3123128 ChemDiv3_014653 CC(C)S(=O)(=O)C1=NSC2=NC(=O)/C(=C\c3ccco3)/C(=N)N12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K02 compound treatment 0.136 -0.0476 -0.5 0.141 -0.0931 -1.11 -1.1407 -0.9346 3040450 ChemDiv3_014654 CCOC(=O)Nc1noc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K03 compound treatment 0.254 0.0704 0.74 0.293 0.0589 0.71 1.0216 0.9997 3123129 ChemDiv3_014655 CCOC(=O)C1=C(CNCc2ccccc2)NC(=O)NC1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K04 compound treatment 0.286 0.102 1.08 0.296 0.0619 0.74 1.2846 0.9835 1506560 ChemDiv3_014656 Cc1ccc(NC(=O)CSc2nc3c(N)ncnc3[nH]2)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K05 compound treatment 0.607 0.423 4.45 0.639 0.405 4.84 6.5703 0.9991 3123130 ChemDiv3_014657 Cc1ccc(s1)C(O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K06 compound treatment 0.29 0.106 1.12 0.334 0.0999 1.2 1.6358 0.9994 3123131 ChemDiv3_014658 Cc1c(oc2c(C)c(C)ccc12)C(=O)N(Cc3ccco3)Cc4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K07 compound treatment 0.625 0.441 4.64 0.653 0.419 5.01 6.8225 0.9992 3040451 ChemDiv3_014659 CCOC(=O)c1oc2ccc3nc(sc3c2c1C)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K08 compound treatment 0.186 0.00242 0.03 0.227 -0.00706 -0.08 -0.0418 -0.4736 1055095 ChemDiv3_014660 CS(=O)(=O)n1cnc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K09 compound treatment 0.632 0.448 4.71 0.718 0.484 5.79 7.4244 0.9947 3123132 ChemDiv3_014661 CCc1cc2n(Cc3ccc(Br)cc3F)c(cc2s1)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K10 compound treatment 0.191 0.00742 0.08 0.283 0.0489 0.59 0.4691 0.7942 3040452 ChemDiv3_014662 CC(C)CNS(=O)(=O)C1CCS(=O)(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K11 compound treatment 0.282 0.0984 1.03 0.406 0.172 2.06 2.1855 0.9493 3123133 ChemDiv3_014663 COc1ccccc1N2C(=O)C3CSC(N3C2=O)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K12 compound treatment 0.055 -0.129 -1.35 0.063 -0.171 -2.05 -2.4021 -0.9796 1145036 ChemDiv3_014664 OC(=O)c1ccn2c(C(=O)c3ccccc3)c(cc2c1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K13 compound treatment 0.228 0.0444 0.47 0.329 0.0949 1.14 1.133 0.9227 3123134 ChemDiv3_014665 CCC(C)NC(=O)c1ccc(CS(=O)Cc2ccc(C)cc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K14 compound treatment 0.868 0.684 7.19 0.945 0.711 8.51 11.0975 0.9965 3123135 ChemDiv3_014666 COc1ccc(OCC(=O)N(Cc2nc(no2)c3ccccc3)C4CCCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K15 compound treatment 0.114 -0.0696 -0.73 0.118 -0.116 -1.39 -1.4987 -0.955 3040453 ChemDiv3_014667 Cc1c(CNC2CCCc3ccccc23)c(C(=O)O)c(C)n1Cc4c(F)cccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K16 compound treatment 0.355 0.171 1.8 0.449 0.215 2.57 3.0914 0.9848 3123136 ChemDiv3_014668 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N2CCCC(C2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K17 compound treatment 0.728 0.544 5.72 0.79 0.556 6.65 8.7464 0.9972 3123137 ChemDiv3_014669 Clc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3C/C=C/c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K18 compound treatment 0.259 0.0754 0.79 0.319 0.0849 1.02 1.2787 0.9924 3040454 ChemDiv3_014670 CN(C(=O)[C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)c4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K19 compound treatment 0.247 0.0634 0.67 0.32 0.0859 1.03 1.198 0.9779 3123138 ChemDiv3_014671 Cc1cc(C)c2c(CC(=O)Nc3c(oc4ccccc34)C(=O)Nc5cccc(Cl)c5)coc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K20 compound treatment 0.401 0.217 2.28 0.374 0.14 1.67 2.7985 0.9884 1613577 ChemDiv3_014672 CCSc1nnc2c(=O)[nH]c(=O)[nH]c2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K21 compound treatment 0.632 0.448 4.71 0.707 0.473 5.66 7.3313 0.9958 1666742 ChemDiv3_014673 O=C(Nc1ccccc1)N2CCCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K22 compound treatment 0.602 0.418 4.39 0.77 0.536 6.41 7.6415 0.983 3040455 ChemDiv3_014674 Cc1c(CCC(=O)O)c(=O)oc2cc3occ(c4ccccc4)c3cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K23 mock treatment 0.162 -0.0216 -0.23 0.181 -0.0531 -0.63 -0.6092 -0.9037 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 K24 mock treatment 0.149 -0.0346 -0.36 0.211 -0.0231 -0.28 -0.4519 -0.9908 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L01 compound treatment 0.485 0.301 3.17 0.505 0.271 3.24 4.5306 0.9999 3123139 ChemDiv3_014675 COc1ccc(cc1)c2coc3cc4oc(=O)c5CCCCCc5c4cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L02 compound treatment 0.311 0.127 1.34 0.407 0.173 2.07 2.4093 0.9778 3123140 ChemDiv3_014676 CC1=C(SCCO1)C(=O)Nc2ccc(CC(=O)N3CCC4(CC3)OCCO4)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L03 compound treatment 0.296 0.112 1.18 0.343 0.109 1.3 1.7565 0.9988 3040456 ChemDiv3_014677 Cc1c2OCN(CCc3ccc(F)cc3)Cc2cc4c5CCCCc5c(=O)oc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L04 compound treatment 0.178 -0.00558 -0.06 0.219 -0.0151 -0.18 -0.1689 -0.8911 3123141 ChemDiv3_014678 Cc1cc(CN2CCN(Cc3ccccc3)CC2)cs1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L05 compound treatment 0.102 -0.0816 -0.86 0.122 -0.112 -1.34 -1.5539 -0.9766 3123142 ChemDiv3_014679 CCOc1ccc2oc(=O)cc(CN(CC3CCCO3)Cc4ccco4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L06 compound treatment 0.464 0.28 2.95 0.559 0.325 3.89 4.8315 0.9906 1010838 ChemDiv3_014680 CCOC(=O)c1cnc(SC)nc1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L07 compound treatment 0.094 -0.0896 -0.94 0.093 -0.141 -1.69 -1.8587 -0.9619 3040457 ChemDiv3_014681 COc1ccc2oc(=O)cc(CN(C)Cc3ccco3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L08 compound treatment 1.337 1.15 12.11 1.374 1.14 13.64 18.2099 0.9983 3123143 ChemDiv3_014682 CC(C)n1c(=O)n(Cc2ccccc2)c3c4ccccc4oc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L09 compound treatment 1.368 1.18 12.44 1.206 0.972 11.63 17.0188 0.9994 3123144 ChemDiv3_014683 CCCN(Cc1cccs1)C(=O)NC2(CC3CC4CC(C3)C2)C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L10 compound treatment 0.338 0.154 1.62 0.388 0.154 1.84 2.4491 0.998 3040458 ChemDiv3_014684 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N4CCCC(C4)C(=O)Nc5ccc(C)cn5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L11 compound treatment 0.236 0.0524 0.55 0.302 0.0679 0.81 0.964 0.982 3123145 ChemDiv3_014685 CCc1nnc2sc(NC(=O)c3ccco3)nn12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L12 compound treatment 0.247 0.0634 0.67 0.362 0.128 1.53 1.5533 0.9305 3123146 ChemDiv3_014686 Cn1c(=O)c2sccc2n3c(CCCC(=O)N4CCCCC4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L13 compound treatment 0.661 0.477 5.01 0.779 0.545 6.52 8.1558 0.9916 3040459 ChemDiv3_014687 CCn1c2ccccc2c3nnc(nc13)N4CCC(C)CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L14 compound treatment 0.367 0.183 1.93 0.512 0.278 3.33 3.7135 0.9663 3123147 ChemDiv3_014688 Cc1ccccc1n2c(SCC(=O)N(CC=C)c3ccccc3)nnc2c4cc5occc5n4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L15 compound treatment 0.253 0.0694 0.73 0.355 0.121 1.45 1.5387 0.9497 3040460 ChemDiv3_014689 O=C(CCCn1c(=O)c2cccn2c3ccccc13)N4CCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L16 compound treatment 0.151 -0.0326 -0.34 0.15 -0.0841 -1.01 -0.9532 -0.8972 3123324 ChemDiv3_014690 CCN(Cc1ccccc1)C(=O)CSc2nc3cccnc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L17 compound treatment 0.243 0.0594 0.62 0.284 0.0499 0.6 0.8637 0.9998 3040461 ChemDiv3_014691 CCCNS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L18 compound treatment 0.088 -0.0956 -1.0 0.097 -0.137 -1.64 -1.8694 -0.9723 3123325 ChemDiv3_014692 CC(C)CCNc1ncnc2n3CCCCCc3nc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L19 compound treatment 0.329 0.145 1.53 0.416 0.182 2.18 2.6192 0.985 3123326 ChemDiv3_014693 CC(NC(=O)C1CCCN(C1)S(=O)(=O)N2CCCCC2)C3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L20 compound treatment 0.235 0.0514 0.54 0.307 0.0729 0.87 0.9989 0.9734 3040462 ChemDiv3_014694 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)Cc4cccs4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L21 compound treatment 0.453 0.269 2.83 0.536 0.302 3.61 4.5553 0.9927 3123327 ChemDiv3_014695 Cc1cc(C)cc(NC(=O)CCCn2c(=O)c3cccn3c4cccnc24)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L22 compound treatment 0.562 0.378 3.97 0.591 0.357 4.27 5.8301 0.9994 3040463 ChemDiv3_014696 CC(C)NC(=O)C1=Cc2sc(C)c(C)c2CS1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L23 mock treatment 0.184 4.19E-4 0.0 0.214 -0.0201 -0.24 -0.1666 -0.694 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 L24 mock treatment 0.154 -0.0296 -0.31 0.204 -0.0301 -0.36 -0.474 -0.9973 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M01 compound treatment 0.222 0.0384 0.4 0.264 0.0299 0.36 0.5386 0.9982 3123328 ChemDiv3_014697 OC(=O)CCc1nnc2ccc(Cl)nn12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M02 compound treatment 0.365 0.181 1.91 0.428 0.194 2.32 2.988 0.9952 3123329 ChemDiv3_014698 COc1ccc(/C=C/C(=O)Nc2noc3ccccc23)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M03 compound treatment 0.12 -0.0636 -0.67 0.157 -0.0771 -0.92 -1.1242 -0.9875 3040464 ChemDiv3_014699 CC(CCc1ccccc1)NC(=O)CCc2nnc3ccc(nn23)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M04 compound treatment 0.533 0.349 3.67 0.667 0.433 5.18 6.2577 0.9858 3123330 ChemDiv3_014700 Cc1c(OCc2ccccc2)ccc3c(cc(=O)oc13)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M05 compound treatment 0.233 0.0494 0.52 0.292 0.0579 0.69 0.8572 0.9898 3123331 ChemDiv3_014701 Cc1ccc(CNC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M06 compound treatment 0.256 0.0724 0.76 0.276 0.0419 0.5 0.8926 0.9796 3040465 ChemDiv3_014702 Brc1ccccc1c2nnc3SCC(=O)Nn23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M07 compound treatment 0.213 0.0294 0.31 0.257 0.0229 0.27 0.4125 0.9982 3040466 ChemDiv3_014703 CN(C)c1nc2ccc3oc(C(=O)O)c(C)c3c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M08 compound treatment 0.096 -0.0876 -0.92 0.092 -0.142 -1.7 -1.8523 -0.9584 3123332 ChemDiv3_014704 CCCNc1nc(SCc2ccc(Cl)cc2)nnc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M09 compound treatment 0.182 -0.00158 -0.02 0.266 0.0319 0.38 0.2584 0.6757 3123333 ChemDiv3_014705 CN1CCC2(CC1)SCC(N2C(=O)C)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M10 compound treatment 0.161 -0.0226 -0.24 0.167 -0.0671 -0.8 -0.7351 -0.8785 1635462 ChemDiv3_014706 C(Nc1ccc2c3[nH]c4ccccc4c3ccc2n1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M11 compound treatment 1.072 0.888 9.33 1.026 0.792 9.48 13.2977 1.0 3123334 ChemDiv3_014707 COc1ccc(cc1)C(=O)Cn2ccnc2C(=O)NCc3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M12 compound treatment 0.203 0.0194 0.2 0.276 0.0419 0.5 0.499 0.9213 3040467 ChemDiv3_014708 Cc1ccc2CCC(CNC(=N)N)Nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M13 compound treatment 0.603 0.419 4.41 0.72 0.486 5.81 7.2259 0.9906 3123335 ChemDiv3_014709 COC(=O)CCSc1ccc(cc1N)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M14 compound treatment 1.051 0.867 9.11 1.211 0.977 11.69 14.7069 0.9924 3123336 ChemDiv3_014710 O=C(N(Cc1nc(no1)c2ccccc2)C3CCCCC3)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M15 compound treatment 0.157 -0.0266 -0.28 0.176 -0.0581 -0.69 -0.6886 -0.9198 3040468 ChemDiv3_014711 Cc1c(CNCCc2cccs2)c(C(=O)O)c(C)n1Cc3c(F)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M16 compound treatment 0.219 0.0354 0.37 0.285 0.0509 0.61 0.694 0.972 3123337 ChemDiv3_014712 O=S(=O)(c1ccccc1)n2nc(nc2NCc3cccs3)c4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M17 compound treatment 0.318 0.134 1.41 0.355 0.121 1.45 2.0214 0.9999 3123338 ChemDiv3_014713 CCOc1ccccc1N2CC(CC2=O)c3nc4ccccc4n3CCCOc5c(C)cccc5C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M18 compound treatment 0.233 0.0494 0.52 0.286 0.0519 0.62 0.8064 0.996 3040469 ChemDiv3_014714 CCCN(C(=O)[C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)c4ccccc4OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M19 compound treatment 0.456 0.272 2.86 0.628 0.394 4.71 5.3559 0.9714 3123339 ChemDiv3_014715 CC(C)c1ccc2occ(CC(=O)Nc3ccc(C)cc3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M20 compound treatment 0.175 -0.00858 -0.09 0.243 0.00894 0.11 0.0119 0.0849 3040470 ChemDiv3_014716 O=C1NN=CC(N1)(c2c[nH]c3ccccc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M21 compound treatment 0.165 -0.0186 -0.2 0.281 0.0469 0.56 0.2591 0.4358 1353075 ChemDiv3_014717 CC(C)(NC(=O)Nc1ccccc1)C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M22 compound treatment 0.512 0.328 3.45 0.628 0.394 4.71 5.7718 0.9882 3123340 ChemDiv3_014718 Cc1c(CCC(=O)O)c(=O)oc2cc3oc4CCCCc4c3cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M23 mock treatment 0.173 -0.0106 -0.11 0.213 -0.0211 -0.25 -0.2568 -0.9323 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 M24 mock treatment 0.167 -0.0166 -0.17 0.239 0.00494 0.06 -0.0814 -0.4426 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N01 compound treatment 0.397 0.213 2.24 0.481 0.247 2.95 3.6741 0.9907 3040471 ChemDiv3_014719 Cc1coc2cc3oc(=O)c(cc3cc12)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N02 compound treatment 0.087 -0.0966 -1.01 0.09 -0.144 -1.72 -1.9361 -0.968 3123341 ChemDiv3_014720 CN(Cc1csc2CCCCc12)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N03 compound treatment 0.78 0.596 6.26 0.759 0.525 6.28 8.8703 1.0 3123342 ChemDiv3_014721 COc1ccc(CCN2COc3c(C)c4oc(=O)cc(c5ccccc5)c4cc3C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N04 compound treatment 0.227 0.0434 0.46 0.315 0.0809 0.97 1.0072 0.941 3040472 ChemDiv3_014722 OCc1cc2CCCCc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N05 compound treatment 0.182 -0.00158 -0.02 0.199 -0.0351 -0.42 -0.3084 -0.7345 3040528 ChemDiv3_014723 CCOc1ccc2oc(=O)cc(CN(Cc3ccco3)C4CCCC4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N06 compound treatment 0.218 0.0344 0.36 0.298 0.0639 0.76 0.7965 0.9414 3040529 ChemDiv3_014724 NCCc1csc2CCCCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N07 compound treatment 0.335 0.151 1.59 0.431 0.197 2.36 2.7906 0.9817 3040530 ChemDiv3_014725 COCCN(Cc1cccs1)Cc2cc(=O)oc3ccc(OC)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N08 compound treatment 0.21 0.0264 0.28 0.257 0.0229 0.27 0.3902 1.0 3040531 ChemDiv3_014726 CCCCn1c(=O)n(CC(=O)N)c2c3ccccc3oc2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N09 compound treatment 0.438 0.254 2.67 0.559 0.325 3.89 4.6384 0.9833 3040532 ChemDiv3_014727 CCc1ccc(CN(Cc2c[nH]nc2c3ccc(OC)cc3)C(=O)NCc4ccc(C)cc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N10 compound treatment 0.229 0.0454 0.48 0.336 0.102 1.22 1.1997 0.9161 3040533 ChemDiv3_014728 Cc1ccc(cc1)S(=O)(=O)c2c(O)c3ccc(cc3[nH]c2=O)C(=O)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N11 compound treatment 0.307 0.123 1.3 0.329 0.0949 1.14 1.7197 0.9978 3040534 ChemDiv3_014729 O=C(Nc1nn2c(nnc2s1)c3ccco3)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N12 compound treatment 0.273 0.0894 0.94 0.315 0.0809 0.97 1.3488 0.9999 3123343 ChemDiv3_014730 CSc1ccc(CCNC(=O)c2oc3cc4sc(nc4cc3c2C)N(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N13 compound treatment 0.214 0.0304 0.32 0.307 0.0729 0.87 0.843 0.9071 3123344 ChemDiv3_014731 CCn1c2ccccc2c3nnc(NCCN4CCN(CC4)c5cc(Cl)ccc5C)nc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N14 compound treatment 0.425 0.241 2.54 0.574 0.34 4.07 4.6688 0.9741 3040535 ChemDiv3_014732 CCC(Sc1nnc(c2cc3occc3n2C)n1c4ccccc4C)C(=O)Nc5ccc(C)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N15 compound treatment 0.231 0.0474 0.5 0.323 0.0889 1.06 1.1046 0.9402 3123345 ChemDiv3_014733 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NCc4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N16 compound treatment 0.286 0.102 1.08 0.293 0.0589 0.71 1.2592 0.979 3123346 ChemDiv3_014734 CCC(C(=O)NCc1ccco1)n2c(SCc3ccc(F)cc3)nc4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N17 compound treatment 0.403 0.219 2.3 0.445 0.211 2.52 3.4141 0.999 3040536 ChemDiv3_014735 CCCN(C(=O)C1C(N(CC(C)C)C(=O)c2ccccc12)c3cccs3)c4ccccc4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N18 compound treatment 0.123 -0.0606 -0.64 0.138 -0.0961 -1.15 -1.2626 -0.9611 3123347 ChemDiv3_014736 C(Nc1ncnc2n3CCCCCc3nc12)c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N19 compound treatment 0.206 0.0224 0.24 0.296 0.0619 0.74 0.6905 0.888 3123348 ChemDiv3_014737 O=C(NCCCN1CCN(CC1)C2CCCCC2)C3CCCN(C3)S(=O)(=O)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N20 compound treatment 0.319 0.135 1.42 0.41 0.176 2.1 2.4941 0.9818 3040537 ChemDiv3_014738 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)c4ccccn4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N21 compound treatment 0.349 0.165 1.74 0.377 0.143 1.71 2.4377 1.0 3123349 ChemDiv3_014739 Cc1c(oc2ccc3OC4(CCCC4)C=Cc3c12)C(=O)NCc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N22 compound treatment 0.264 0.0804 0.84 0.313 0.0789 0.94 1.265 0.9984 3040538 ChemDiv3_014740 Cc1sc2C=C(SCc2c1C)C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N23 mock treatment 0.18 -0.00358 -0.04 0.213 -0.0211 -0.25 -0.2048 -0.8037 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 N24 mock treatment 0.154 -0.0296 -0.31 0.196 -0.0381 -0.46 -0.5417 -0.9826 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O01 compound treatment 0.249 0.0654 0.69 0.302 0.0679 0.81 1.0606 0.9965 3040539 ChemDiv3_014741 NNc1ccc2nncn2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O02 compound treatment 0.553 0.369 3.88 0.593 0.359 4.29 5.7801 0.9987 3123350 ChemDiv3_014742 O=C(Cc1cccs1)Nc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O03 compound treatment 0.203 0.0194 0.2 0.26 0.0259 0.31 0.3636 0.9793 3123351 ChemDiv3_014743 COC(=O)c1ccc2oc(=O)c(cc2c1)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O04 compound treatment 0.304 0.12 1.26 0.349 0.115 1.38 1.8667 0.9991 1527932 ChemDiv3_014744 CC(C)C(=O)Oc1ccc2c(C)cc(=O)oc2c1C(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O05 compound treatment 0.317 0.133 1.4 0.358 0.124 1.48 2.0394 0.9996 3120289 ChemDiv3_014745 CCNc1cc(N2CCCC2)c3noc4-c5ccccc5C(=O)c1c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O06 compound treatment 0.051 -0.133 -1.39 0.057 -0.177 -2.12 -2.4826 -0.9793 3040540 ChemDiv3_014746 O=C1CSc2nnc(C3COc4ccccc4O3)n2N1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O07 compound treatment 0.141 -0.0426 -0.45 0.16 -0.0741 -0.89 -0.9428 -0.9499 3120290 ChemDiv3_014747 CCOC(=O)c1oc2cc3sc(nc3cc2c1C)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O08 compound treatment 0.211 0.0274 0.29 0.25 0.0159 0.19 0.3384 0.9799 3040541 ChemDiv3_014748 Cn1c(nc2ccccc12)C3=C(N)N(CC3=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O09 compound treatment 0.232 0.0484 0.51 0.281 0.0469 0.56 0.7567 0.9988 3120291 ChemDiv3_014749 CCOC(=O)c1c(NC(=O)C)c2c3CCCCc3sc2n1Cc4ccc(F)cc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O10 compound treatment 0.194 0.0104 0.11 0.241 0.00694 0.08 0.1361 0.9907 1355670 ChemDiv3_014750 CC(=O)Nc1ccc2nc3c(cc2c1)[nH]c4ccccc43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O11 compound treatment 0.271 0.0874 0.92 0.299 0.0649 0.78 1.1986 0.9965 3040542 ChemDiv3_014751 CCN(c1ccccc1)S(=O)(=O)N2CCCC(C2)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O12 compound treatment 0.222 0.0384 0.4 0.263 0.0289 0.35 0.5301 0.9971 1569429 ChemDiv3_014752 CN(C)CCn1c(=O)n(C)c2nc[nH]c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O13 compound treatment 0.282 0.0984 1.03 0.336 0.102 1.22 1.5933 0.9966 3040543 ChemDiv3_014753 OC(=O)C1=C(OCCS1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O14 compound treatment 0.059 -0.125 -1.31 0.063 -0.171 -2.05 -2.3724 -0.9766 3120292 ChemDiv3_014754 CC(C)(C)C(=O)N(Cc1nc(no1)c2ccccc2)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O15 compound treatment 0.099 -0.0846 -0.89 0.125 -0.109 -1.3 -1.5508 -0.9824 3120293 ChemDiv3_014755 Cc1c(CNCCC2=CCCCC2)c(C(=O)O)c(C)n1Cc3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O16 compound treatment 0.564 0.38 4.0 0.63 0.396 4.74 6.1749 0.9964 3040544 ChemDiv3_014756 COc1ccc(CNc2nc(nn2S(=O)(=O)C)c3cccnc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O17 compound treatment 0.252 0.0684 0.72 0.251 0.0169 0.2 0.6514 0.8725 3040545 ChemDiv3_014757 CC(O)c1nc2cc(C)ccc2[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O18 compound treatment 0.203 0.0194 0.2 0.237 0.00294 0.04 0.1691 0.8168 3120294 ChemDiv3_014758 CC(C)N(Cc1cccs1)C(=O)[C@H]2[C@H]3C[C@H]4OC(=O)[C@@H]2[C@H]4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O19 compound treatment 0.14 -0.0436 -0.46 0.178 -0.0561 -0.67 -0.798 -0.9826 3120295 ChemDiv3_014759 C=CCn1c2ccccc2c3nnc(SCC(=O)NC4=NN=C(CS4)c5ccccc5)nc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O20 compound treatment 0.117 -0.0666 -0.7 0.138 -0.0961 -1.15 -1.3072 -0.9716 3040546 ChemDiv3_014760 Cc1cc(C)c(C(=O)CC(N2CCCCC2)C(F)(F)F)c(=O)[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O21 compound treatment 0.199 0.0154 0.16 0.28 0.0459 0.55 0.5031 0.8781 3120296 ChemDiv3_014761 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nn3cnnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O22 compound treatment 0.254 0.0704 0.74 0.354 0.12 1.43 1.5376 0.9525 3040547 ChemDiv3_014762 Cc1c(CC(=O)O)c(=O)oc2c(C)c3occ(c3cc12)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O23 mock treatment 0.162 -0.0216 -0.23 0.23 -0.00406 -0.05 -0.1947 -0.8397 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 O24 mock treatment 0.163 -0.0206 -0.22 0.245 0.0109 0.13 -0.0603 -0.2388 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P01 compound treatment 0.229 0.0454 0.48 0.314 0.0799 0.96 1.0136 0.9484 3120297 ChemDiv3_014763 Cc1ccc(CN2COc3c(Cl)cc4c(C)c(C)c(=O)oc4c3C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P02 compound treatment 0.32 0.136 1.43 0.364 0.13 1.55 2.1124 0.9992 3040548 ChemDiv3_014764 C(N1CCc2ccccc12)c3csc4CCCCc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P03 compound treatment 0.299 0.115 1.21 0.331 0.0969 1.16 1.6773 0.9998 3120298 ChemDiv3_014765 Cc1c(CCC(=O)NCc2ccccc2)c(=O)oc3cc(O)ccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P04 compound treatment 0.147 -0.0366 -0.38 0.174 -0.0601 -0.72 -0.7798 -0.957 3040549 ChemDiv3_014766 CCCN(CCC)Cc1csc2CCCCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P05 compound treatment 0.367 0.183 1.93 0.436 0.202 2.42 3.0706 0.9937 3120299 ChemDiv3_014767 CN(Cc1cc(=O)oc2cc(C)ccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P06 compound treatment 0.133 -0.0506 -0.53 0.159 -0.0751 -0.9 -1.0107 -0.9686 3040550 ChemDiv3_014768 Cc1cc(CSC(=N)N)cs1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P07 compound treatment 0.108 -0.0756 -0.79 0.114 -0.12 -1.44 -1.5771 -0.9609 3120300 ChemDiv3_014769 COc1ccc2oc(=O)cc(CN(Cc3cccs3)C(C)C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P08 compound treatment 1.154 0.97 10.19 1.201 0.967 11.57 15.3872 0.998 3040551 ChemDiv3_014770 Cc1ccc(Cn2c(=O)n(c3ccc(C)c(C)c3)c(=O)c4oc5ccccc5c24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P09 compound treatment 0.295 0.111 1.17 0.379 0.145 1.73 2.0536 0.9817 3120301 ChemDiv3_014771 Clc1ccc2n(ncc2c1)C(=O)NC3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P10 compound treatment 0.152 -0.0316 -0.33 0.22 -0.0141 -0.17 -0.3535 -0.9505 3120302 ChemDiv3_014772 O=C(CCNS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P11 compound treatment 0.192 0.00842 0.09 0.263 0.0289 0.35 0.3073 0.8601 3040552 ChemDiv3_014773 CCCc1nnc2sc(NC(=O)CC)nn12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P12 compound treatment 0.133 -0.0506 -0.53 0.166 -0.0681 -0.81 -0.9515 -0.9786 3120303 ChemDiv3_014774 CN(C)c1nc2ccc3oc(C(=O)NCCCN4CCCCCC4)c(C)c3c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P13 compound treatment 0.224 0.0404 0.42 0.259 0.0249 0.3 0.5111 0.9851 3040553 ChemDiv3_014775 CCn1c2ccccc2c3nnc(NCCOc4cccc(c4)C(F)(F)F)nc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P14 compound treatment 0.404 0.22 2.31 0.499 0.265 3.17 3.8783 0.9881 3120304 ChemDiv3_014776 COc1ccc(Cl)cc1n2c(SCc3cccc(Cl)c3)nnc2c4cc5occc5n4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P15 compound treatment 0.247 0.0634 0.67 0.305 0.0709 0.85 1.0711 0.9928 3040554 ChemDiv3_014777 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NC4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P16 compound treatment 0.257 0.0734 0.77 0.348 0.114 1.36 1.5092 0.9636 3120305 ChemDiv3_014778 CCC(C(=O)Nc1cccc(OC)c1)n2c(SCc3ccc(C)cc3)nc4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P17 compound treatment 0.227 0.0434 0.46 0.273 0.0389 0.47 0.6519 0.9999 3120306 ChemDiv3_014779 CCC(C)NC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P18 compound treatment 0.152 -0.0316 -0.33 0.157 -0.0771 -0.92 -0.8865 -0.9047 3040555 ChemDiv3_014780 CCOc1ccccc1CNc2ncnc3n4CCCCCc4nc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P19 compound treatment 0.273 0.0894 0.94 0.296 0.0619 0.74 1.1881 0.9931 3120307 ChemDiv3_014781 COc1ccc2c(CNCC(C)c3ccccc3)c(C(=O)O)n(Cc4ccc(F)cc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P20 compound treatment 0.229 0.0454 0.48 0.241 0.00694 0.08 0.396 0.8178 3040556 ChemDiv3_014782 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)CSc4ccncc4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P21 compound treatment 0.266 0.0824 0.87 0.305 0.0709 0.85 1.2122 1.0 3120308 ChemDiv3_014783 Cc1c(oc2ccc3OC4(CCCC4)C=Cc3c12)C(=O)NC5CCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P22 compound treatment 0.188 0.00442 0.05 0.197 -0.0371 -0.44 -0.2808 -0.6297 3120309 ChemDiv3_014784 O=C(NCc1ccccc1)C2=Cc3sc4CCCCc4c3CS2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P23 mock treatment 0.191 0.00742 0.08 0.25 0.0159 0.19 0.1899 0.9221 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2042 P24 mock treatment 0.179 -0.00458 -0.05 0.242 0.00794 0.09 0.0331 0.3111 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A01 compound treatment 0.193 -0.0813 -0.85 0.178 -0.0596 -0.71 -1.108 -0.996 3040557 ChemDiv3_014785 O=C(NCCN1CCCC1)C2=Cc3sc4CCCCc4c3CS2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A02 compound treatment 0.306 0.0317 0.33 0.198 -0.0396 -0.47 -0.0996 -0.1721 1691169 ChemDiv3_014786 O=C(Nc1ccccc1C(=O)N2CCOCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A03 compound treatment 0.608 0.334 3.5 0.494 0.256 3.07 4.6474 0.9978 3040558 ChemDiv3_014787 CCC(C)NS(=O)(=O)c1ccc(cc1)n2cccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A04 compound treatment 0.307 0.0327 0.34 0.21 -0.0276 -0.33 0.0093 0.0195 1301241 ChemDiv3_014788 CCNc1c2C(=O)CC(C)(C)Cc2nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A05 compound treatment 0.398 0.124 1.3 0.33 0.0924 1.11 1.7003 0.9968 3120310 ChemDiv3_014789 O=S(=O)(Nc1ccc(cc1)c2ccno2)c3ccc(cc3)n4cccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A06 compound treatment 0.184 -0.0903 -0.95 0.167 -0.0706 -0.84 -1.2679 -0.9983 1714116 ChemDiv3_014790 Cc1cc(O)n(CCc2ccccc2)c(=O)c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A07 compound treatment 0.382 0.108 1.13 0.438 0.2 2.4 2.4952 0.9412 3120311 ChemDiv3_014791 CCOC(=O)c1cc(C)n(CC2CCC(CC2)C(=O)Nc3ccccc3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A08 compound treatment 0.229 -0.0453 -0.48 0.199 -0.0386 -0.46 -0.663 -0.9999 3040559 ChemDiv3_014792 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A09 compound treatment 0.891 0.617 6.48 0.78 0.542 6.49 9.1687 1.0 3120312 ChemDiv3_014793 CN(Cc1ccccc1)C(=O)c2cc(n[nH]2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A10 compound treatment 0.277 0.00269 0.03 0.27 0.0324 0.39 0.2941 0.7566 1387657 ChemDiv3_014794 COc1ccccc1C2(CC(=O)O)CCOC(C)(C)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A11 compound treatment 0.193 -0.0813 -0.85 0.178 -0.0596 -0.71 -1.108 -0.996 3040560 ChemDiv3_014795 CN1CCC2(CC1)SCC(N2C(=O)C)C(=O)NCc3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A12 compound treatment 0.354 0.0797 0.84 0.317 0.0794 0.95 1.2636 0.998 1163694 ChemDiv3_014796 CCOC(=O)C(C#N)C1(CCOC(C)(C)C1)c2ccccc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A13 compound treatment 0.13 -0.144 -1.52 0.117 -0.121 -1.44 -2.092 -0.9997 3040561 ChemDiv3_014797 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2c(C)n(C)c(=O)n(C)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A14 compound treatment 0.59 0.316 3.32 0.467 0.229 2.74 4.2853 0.9956 1604258 ChemDiv3_014798 Cc1cc(OCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)cc(C)c1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A15 compound treatment 0.415 0.141 1.48 0.364 0.126 1.51 2.1142 0.9999 1918523 ChemDiv3_014799 Cc1nc2cc(CCO)ccc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A16 compound treatment 0.121 -0.153 -1.61 0.122 -0.116 -1.38 -2.1165 -0.9971 3040562 ChemDiv3_014800 CN/1CCCCC\C1=N\c2cccc(F)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A17 compound treatment 0.205 -0.0693 -0.73 0.184 -0.0536 -0.64 -0.9682 -0.998 1448263 ChemDiv3_014801 CC(=C)C1Cc2nc(N)nc(C)c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A18 compound treatment 0.132 -0.142 -1.49 0.116 -0.122 -1.45 -2.0856 -0.9999 3120490 ChemDiv3_014802 COc1ccc(CNc2cc(C)ccn2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A19 compound treatment 0.296 0.0217 0.23 0.267 0.0294 0.35 0.4098 0.9779 1082159 ChemDiv3_014803 CCNC(=O)Nc1nc2ccccc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A20 compound treatment 0.367 0.0927 0.97 0.336 0.0984 1.18 1.5209 0.9955 3040619 ChemDiv3_014804 Cc1ccc2[nH]c(nc2c1)C(O)C(O)c3nc4cc(C)ccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A21 compound treatment 0.542 0.268 2.81 0.465 0.227 2.72 3.9119 0.9999 1518446 ChemDiv3_014805 COc1ccc(OCC(O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A22 compound treatment 0.269 -0.00531 -0.06 0.246 0.00841 0.1 0.0317 0.2753 1354832 ChemDiv3_014806 COc1cc2C(C)NCC3(CCCC3)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A23 mock treatment 0.259 -0.0153 -0.16 0.295 0.0574 0.69 0.3719 0.5273 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 A24 mock treatment 0.345 0.0707 0.74 0.261 0.0234 0.28 0.723 0.9112 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B01 compound treatment 0.367 0.0927 0.97 0.272 0.0344 0.41 0.9794 0.9267 3040620 ChemDiv3_014807 CCOc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nn4c(C)nnc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B02 compound treatment 0.306 0.0317 0.33 0.223 -0.0146 -0.17 0.1119 0.2976 3040621 ChemDiv3_014808 CCOc1cc(C)c(Cl)cc1S(=O)(=O)Nc2ccccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B03 compound treatment 0.311 0.0367 0.39 0.22 -0.0176 -0.21 0.1236 0.2815 3040622 ChemDiv3_014809 CCCN(c1ccccc1C(=O)O)S(=O)(=O)c2ccc3n(C)c(=O)n(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B04 compound treatment 0.195 -0.0793 -0.83 0.169 -0.0686 -0.82 -1.1693 -1.0 1448023 ChemDiv3_014810 COc1ccc2n(C)c(COc3ccccc3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B05 compound treatment 0.332 0.0577 0.61 0.295 0.0574 0.69 0.9141 0.998 3120491 ChemDiv3_014811 OC(CN1CCCCC1)Cn2ccc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B06 compound treatment 0.192 -0.0823 -0.86 0.173 -0.0646 -0.77 -1.1578 -0.9984 3040623 ChemDiv3_014812 O=c1nc(NCc2ccco2)cc[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B07 compound treatment 0.129 -0.145 -1.53 0.114 -0.124 -1.48 -2.1248 -0.9999 3120492 ChemDiv3_014813 Cc1ccnc(NC(=O)CCC2COc3ccccc3O2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B08 compound treatment 0.699 0.425 4.46 0.708 0.47 5.63 7.1336 0.9934 3120493 ChemDiv3_014814 COc1cccc(c1)c2cc(n3ncc(C(=O)NC4CCCC4)c3n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B09 compound treatment 0.183 -0.0913 -0.96 0.151 -0.0866 -1.04 -1.4107 -0.9993 3040624 ChemDiv3_014815 CCc1nnc(s1)N2CCN(CC2)c3ncnc4c5ccccc5oc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B10 compound treatment 0.456 0.182 1.91 0.402 0.164 1.97 2.7402 0.9999 3120494 ChemDiv3_014816 CCC1CCCCN1C(=O)c2cc(on2)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B11 compound treatment 0.429 0.155 1.62 0.398 0.16 1.92 2.5058 0.9966 3120495 ChemDiv3_014817 Cc1cc(C)nc(n1)N2C(=O)CC(N=C2NCCc3c[nH]c4ccccc34)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B12 compound treatment 0.134 -0.14 -1.47 0.109 -0.129 -1.54 -2.13 -0.9998 3040625 ChemDiv3_014818 CC1(C)CC(=Nc2ccccc2N1)/C=C/c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B13 compound treatment 1.054 0.78 8.19 1.127 0.889 10.64 13.3149 0.9916 3040626 ChemDiv3_014819 CC1(C)COC(=N1)N(C(=O)NC2CCCCC2)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B14 compound treatment 0.735 0.461 4.84 0.602 0.364 4.36 6.5042 0.9986 3120496 ChemDiv3_014820 O=C1CC(=NN1c2nc3ccccc3[nH]2)CSc4nnnn4c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B15 compound treatment 0.357 0.0827 0.87 0.234 -0.00359 -0.04 0.5837 0.6713 3120497 ChemDiv3_014821 CCOc1cc(CNC2CN3CCC2CC3)ccc1OCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B16 compound treatment 0.248 -0.0263 -0.28 0.201 -0.0366 -0.44 -0.505 -0.9754 3040627 ChemDiv3_014822 COc1cc(NC(=O)C2CC(=O)NC3=C2C(=O)CC(C)(C)C3)c(OC)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B17 compound treatment 0.37 0.0957 1.0 0.288 0.0504 0.6 1.1371 0.9702 3120498 ChemDiv3_014823 CC1SC(=NC1=O)NC(=O)CSc2nc(C)cc(C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B18 compound treatment 0.322 0.0477 0.5 0.239 0.00141 0.02 0.366 0.7304 3120499 ChemDiv3_014824 COC(=O)C1=NOC2(CC(=O)N(C2=O)c3ccc(Cl)cc3)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B19 compound treatment 0.112 -0.162 -1.7 0.1 -0.138 -1.65 -2.3695 -0.9998 3040628 ChemDiv3_014825 Cc1ccc(CNc2ccc3n(cnc3c2)C4CCCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B20 compound treatment 0.898 0.624 6.55 0.793 0.555 6.65 9.3306 1.0 3120500 ChemDiv3_014826 CCOC(=O)Cc1sc(Nc2ccccn2)nc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B21 compound treatment 0.241 -0.0333 -0.35 0.235 -0.00259 -0.03 -0.2693 -0.7668 3040629 ChemDiv3_014827 COC(=O)c1ccc(OCCN2C3=NCCN3c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B22 compound treatment 0.36 0.0857 0.9 0.287 0.0494 0.59 1.0543 0.9792 3120501 ChemDiv3_014828 Cn1c(=O)cc(Nc2ccc(F)c(Cl)c2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B23 mock treatment 0.344 0.0697 0.73 0.317 0.0794 0.95 1.1893 0.9917 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 B24 mock treatment 0.305 0.0307 0.32 0.242 0.00441 0.05 0.2652 0.812 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C01 compound treatment 0.224 -0.0503 -0.53 0.182 -0.0556 -0.67 -0.844 -0.9935 3120502 ChemDiv3_014829 CCOC(=O)c1cnc(SCC(=O)NCc2ccco2)nc1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C02 compound treatment 0.275 6.88E-4 0.01 0.192 -0.0456 -0.55 -0.3806 -0.6977 1168895 ChemDiv3_014830 Cc1ccccc1NC(=O)Cn2nc(C)c3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C03 compound treatment 0.359 0.0847 0.89 0.306 0.0684 0.82 1.2077 0.9991 3120503 ChemDiv3_014831 O=S(=O)(NC1CCCC1)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C04 compound treatment 0.202 -0.0723 -0.76 0.214 -0.0236 -0.28 -0.7366 -0.9092 3040630 ChemDiv3_014832 Cc1cc(C)nc(NC(=N)Nc2ccccc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C05 compound treatment 0.243 -0.0313 -0.33 0.208 -0.0296 -0.35 -0.4829 -0.9993 3120504 ChemDiv3_014833 CCOC(=O)C1=C(CN2CCC(C)CC2)NC(=O)NC1c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C06 compound treatment 0.328 0.0537 0.56 0.238 4.06E-4 0.0 0.4021 0.7132 3444261 ChemDiv3_014834 CC(C)C(NC(=O)C1(CC2CC3CC(C2)C1)C3)C(=O)Nc4nc5ccccc5s4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C07 compound treatment 0.19 -0.0843 -0.89 0.196 -0.0416 -0.5 -0.978 -0.9629 3040631 ChemDiv3_014835 Cc1ccccc1Nc2nn3c(=O)c4ccc(cc4nc3s2)C(=O)NCCC5=CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C08 compound treatment 0.33 0.0557 0.58 0.202 -0.0356 -0.43 0.1124 0.1554 1263817 ChemDiv3_014836 Cc1ccc2c(O)c(CN3CCCC3)c(C)nc2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C09 compound treatment 0.738 0.464 4.87 0.577 0.339 4.06 6.315 0.9959 3040632 ChemDiv3_014837 CN(C1CCCCC1)C(=O)c2cc(n[nH]2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C10 compound treatment 0.233 -0.0413 -0.43 0.193 -0.0446 -0.53 -0.6841 -0.9947 1272029 ChemDiv3_014838 COc1ccc(cc1)c2nc(NCC3CCCO3)c4ccccc4n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C11 compound treatment 0.247 -0.0273 -0.29 0.158 -0.0796 -0.95 -0.8762 -0.881 3040633 ChemDiv3_014839 CCCC1Nc2ccccc2S(=O)(=O)N1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C12 compound treatment 0.403 0.129 1.35 0.254 0.0164 0.2 1.0945 0.8014 1261807 ChemDiv3_014840 COc1ccccc1C2(CC#N)CCOC(C)(C)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C13 compound treatment 0.679 0.405 4.25 0.607 0.369 4.42 6.1306 0.9998 3120505 ChemDiv3_014841 O=S(=O)(N1CCCC1)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C14 compound treatment 0.217 -0.0573 -0.6 0.175 -0.0626 -0.75 -0.9552 -0.9941 1626639 ChemDiv3_014842 COc1ccc2[nH]c3C(CC(=O)O)NCCc3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C15 compound treatment 0.492 0.218 2.29 0.284 0.0464 0.56 2.0093 0.854 1136077 ChemDiv3_014843 COc1ccc2[nH]cc(CCN3C(=O)c4ccccc4C3=O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C16 compound treatment 0.231 -0.0433 -0.45 0.182 -0.0556 -0.67 -0.792 -0.9828 3120506 ChemDiv3_014844 NC(=O)c1c2NCCc2cnc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C17 compound treatment 0.307 0.0327 0.34 0.235 -0.00259 -0.03 0.2208 0.6406 1388285 ChemDiv3_014845 CC(CC(=O)NCc1ccccc1)C2CCCO2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C18 compound treatment 0.352 0.0777 0.82 0.327 0.0894 1.07 1.3333 0.9911 3120507 ChemDiv3_014846 Cc1ccc(cc1)S(=O)(=O)N2CCn3c2nc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C19 compound treatment 0.254 -0.0203 -0.21 0.24 0.00241 0.03 -0.1305 -0.6062 1718335 ChemDiv3_014847 OC1(CN2CCC1CC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C20 compound treatment 0.335 0.0607 0.64 0.286 0.0484 0.58 0.8602 0.9989 3120508 ChemDiv3_014848 Cc1cccc(c1)C(=O)Nc2nc3cc4sc(NC(=O)c5cccc(C)c5)nc4cc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C21 compound treatment 0.286 0.0117 0.12 0.212 -0.0256 -0.31 -0.1297 -0.3932 1426520 ChemDiv3_014849 CN(C)CCSc1nc2ccccc2[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C22 compound treatment 0.279 0.00469 0.05 0.266 0.0284 0.34 0.2751 0.8012 3040634 ChemDiv3_014850 CCC(C)Cn1c(C)c2c(=O)n([nH]c2cc1=O)c3nc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C23 mock treatment 0.324 0.0497 0.52 0.318 0.0804 0.96 1.0493 0.9587 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 C24 mock treatment 0.296 0.0217 0.23 0.292 0.0544 0.65 0.6213 0.901 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D01 compound treatment 0.252 -0.0223 -0.23 0.22 -0.0176 -0.21 -0.3145 -0.9986 3120509 ChemDiv3_014851 CCOc1ccc(cc1)C2N(CC3CCCO3)C(=O)c4oc5ccc(F)cc5c(=O)c24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D02 compound treatment 0.237 -0.0373 -0.39 0.21 -0.0276 -0.33 -0.5105 -0.9964 3040635 ChemDiv3_014852 O=c1[nH]c(nc2CCCCc21)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D03 compound treatment 0.252 -0.0223 -0.23 0.214 -0.0236 -0.28 -0.3653 -0.9957 3120510 ChemDiv3_014853 CN(c1ccccc1C(=O)O)S(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D04 compound treatment 0.445 0.171 1.79 0.378 0.14 1.68 2.4555 0.9995 3120511 ChemDiv3_014854 COc1nccnc1NS(=O)(=O)c2ccc(NCc3cc(Br)ccc3O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D05 compound treatment 0.319 0.0447 0.47 0.256 0.0184 0.22 0.4876 0.9405 3040636 ChemDiv3_014855 OC(Cn1ccc2ccccc12)Cn3cnc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D06 compound treatment 0.114 -0.16 -1.68 0.102 -0.136 -1.62 -2.3377 -0.9998 3123741 ChemDiv3_014856 O=C1N(CC2CC(=NO2)c3ccccc3)S(=O)(=O)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D07 compound treatment 0.042 -0.232 -2.44 0.042 -0.196 -2.34 -3.38 -0.9998 3040637 ChemDiv3_014857 COc1cccc(c1)n2nnnc2S(=O)(=O)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D08 compound treatment 0.467 0.193 2.02 0.325 0.0874 1.05 2.1705 0.9528 3123742 ChemDiv3_014858 Fc1cccc(Cl)c1C2=NOC(C2)C(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D09 compound treatment 0.348 0.0737 0.77 0.219 -0.0186 -0.22 0.3899 0.4842 3040638 ChemDiv3_014859 CCn1c(COc2ccccc2C(=O)N)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D10 compound treatment 0.431 0.157 1.65 0.301 0.0634 0.76 1.7001 0.9382 3123743 ChemDiv3_014860 Cc1ccc(cc1)c2cc(no2)C(=O)NC(C)(C)CO 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D11 compound treatment 0.939 0.665 6.98 0.884 0.646 7.73 10.405 0.9987 3123744 ChemDiv3_014861 Cc1nc(Nc2nc3ccccc3o2)ncc1C(=O)Nc4cccc(c4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D12 compound treatment 0.106 -0.168 -1.77 0.097 -0.141 -1.68 -2.4394 -0.9997 3040639 ChemDiv3_014862 CN(C)c1ccc(/C=C/C2=Nc3ccccc3SC(C)(C)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D13 compound treatment 0.278 0.00369 0.04 0.264 0.0264 0.32 0.2508 0.7879 3123745 ChemDiv3_014863 CCc1ccc(NC(=O)C2CC(=O)n3c(N2)nc4ccccc34)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D14 compound treatment 0.305 0.0307 0.32 0.216 -0.0216 -0.26 0.0452 0.1095 1038239 ChemDiv3_014864 Cc1nc2ccc(cc2s1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D15 compound treatment 0.344 0.0697 0.73 0.25 0.0124 0.15 0.6225 0.8335 3040640 ChemDiv3_014865 CSc1ccc(CNC2CN3CCC2CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D16 compound treatment 0.339 0.0647 0.68 0.268 0.0304 0.36 0.7376 0.9572 3123746 ChemDiv3_014866 COc1cc(NC(=O)C2CC(=O)NC3=C2C(=O)CCC3)cc(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D17 compound treatment 0.264 -0.0103 -0.11 0.192 -0.0456 -0.55 -0.4623 -0.8313 3040641 ChemDiv3_014867 CCN(CC)CCn1nc(C)nc1c2ccccc2O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D18 compound treatment 0.242 -0.0323 -0.34 0.208 -0.0296 -0.35 -0.4903 -0.9998 1674400 ChemDiv3_014868 CCCN1C(=O)C(O)(c2c[nH]c3ccccc23)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D19 compound treatment 0.114 -0.16 -1.68 0.086 -0.152 -1.81 -2.4731 -0.9993 3123747 ChemDiv3_014869 COc1cccc(CNc2ccc3n(cnc3c2)C4CCCCC4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D20 compound treatment 0.217 -0.0573 -0.6 0.181 -0.0566 -0.68 -0.9044 -0.9983 3040642 ChemDiv3_014870 COc1ccc2c3CCNC(C)(C(=O)O)c3[nH]c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D21 compound treatment 0.673 0.399 4.19 0.651 0.413 4.95 6.4583 0.9966 3123748 ChemDiv3_014871 Cc1cc(ccc1NC(=O)C(C)(C)Oc2ccc(Cl)cc2)c3nc4ncccc4o3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D22 compound treatment 0.201 -0.0733 -0.77 0.178 -0.0596 -0.71 -1.0486 -0.9993 3123749 ChemDiv3_014872 COc1ccccc1Nc2c3CCCCc3nc4ccc(NC(=O)COc5cccc(C)c5)cc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D23 mock treatment 0.329 0.0547 0.57 0.282 0.0444 0.53 0.7818 0.9992 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 D24 mock treatment 0.288 0.0137 0.14 0.223 -0.0146 -0.17 -0.0218 -0.0965 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E01 compound treatment 0.309 0.0347 0.36 0.251 0.0134 0.16 0.371 0.9321 3040643 ChemDiv3_014873 CCOC(=O)c1cnc(SCC(=O)N(C)c2ccccc2)nc1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E02 compound treatment 0.152 -0.122 -1.28 0.12 -0.118 -1.41 -1.9032 -0.999 1586676 ChemDiv3_014874 CN(C)CCOC(=O)C1(CCCC1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E03 compound treatment 0.802 0.528 5.54 0.694 0.456 5.46 7.7801 1.0 3123750 ChemDiv3_014875 CN(C1CCCCC1)S(=O)(=O)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E04 compound treatment 0.294 0.0197 0.21 0.241 0.00341 0.04 0.175 0.8305 1574583 ChemDiv3_014876 CCc1ccc(cc1)S(=O)(=O)N2CC(=O)Nc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E05 compound treatment 0.158 -0.116 -1.22 0.154 -0.0836 -1.0 -1.571 -0.9951 3040644 ChemDiv3_014877 CCc1ccc(cc1)N2COc3ccc4cc(C(=O)OC)c(=O)oc4c3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E06 compound treatment 0.198 -0.0763 -0.8 0.19 -0.0476 -0.57 -0.9694 -0.986 3123751 ChemDiv3_014878 COc1cc2CC(C)(C)N=C(C)c2cc1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E07 compound treatment 0.486 0.212 2.22 0.408 0.17 2.04 3.0138 0.9991 3123752 ChemDiv3_014879 Cc1ccccc1Nc2nn3c(=O)c4ccc(cc4nc3s2)C(=O)NCc5ccccc5Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E08 compound treatment 0.231 -0.0433 -0.45 0.16 -0.0776 -0.93 -0.9781 -0.9461 3040645 ChemDiv3_014880 COc1ccc2n3CCN(C)/C(=N\C)/c3c(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E09 compound treatment 0.437 0.163 1.71 0.328 0.0904 1.08 1.973 0.9757 3040646 ChemDiv3_014881 CC(C)CN(CC(C)C)C(=O)c1cc(n[nH]1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E10 compound treatment 0.572 0.298 3.13 0.468 0.23 2.76 4.16 0.998 1286750 ChemDiv3_014882 Cc1ccc2n(CC(O)CN3C(=O)CNC3=O)c(c(c4ccccc4)c2c1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E11 compound treatment 0.441 0.167 1.75 0.31 0.0724 0.87 1.8505 0.9474 3040647 ChemDiv3_014883 Brc1cccc(c1)C2Nc3ccccc3S(=O)(=O)N2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E12 compound treatment 0.17 -0.104 -1.1 0.151 -0.0866 -1.04 -1.5073 -0.9996 1123038 ChemDiv3_014884 COc1ccc2n3CCNC4CCCc(c43)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E13 compound treatment 0.481 0.207 2.17 0.41 0.172 2.06 2.9935 0.9997 3041041 ChemDiv3_014885 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)NCC4CCC(CC4)C(=O)Nc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E14 compound treatment 0.334 0.0597 0.63 0.226 -0.0116 -0.14 0.3452 0.5376 1875958 ChemDiv3_014886 CCc1[nH]c(=O)c(C#N)c2CCCCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E15 compound treatment 0.651 0.377 3.96 0.578 0.34 4.07 5.6774 0.9999 3041042 ChemDiv3_014887 Cc1ccc2nc(oc2c1)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E16 compound treatment 0.238 -0.0363 -0.38 0.249 0.0114 0.14 -0.1732 -0.4275 3041043 ChemDiv3_014888 C1CC(CCN1)c2cc([nH]n2)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E17 compound treatment 0.358 0.0837 0.88 0.313 0.0754 0.9 1.2595 0.9999 1439469 ChemDiv3_014889 Cn1c(CNc2ccccc2)cc(=O)n(C)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E18 compound treatment 0.353 0.0787 0.83 0.334 0.0964 1.15 1.4 0.9866 3041044 ChemDiv3_014890 Cn1nc(c2ccc(cc2)C(=O)N)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E19 compound treatment 0.487 0.213 2.23 0.364 0.126 1.51 2.6489 0.982 3041045 ChemDiv3_014891 Clc1ccc(NC(=O)NCCCn2ccnc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E20 compound treatment 0.454 0.18 1.89 0.302 0.0644 0.77 1.8793 0.9219 3041046 ChemDiv3_014892 Cn1nc(C(=O)N2CCCC2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E21 compound treatment 0.842 0.568 5.96 0.753 0.515 6.17 8.5763 0.9999 1576461 ChemDiv3_014893 Cc1cc(C)n(CC(O)CN2c3ccccc3Sc4ccccc24)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E22 compound treatment 0.413 0.139 1.46 0.353 0.115 1.38 2.0063 0.9996 3123753 ChemDiv3_014894 COc1ccc(CCn2c(C)c3c(=O)n([nH]c3cc2=O)c4nc5ccccc5s4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E23 mock treatment 0.306 0.0317 0.33 0.235 -0.00259 -0.03 0.2134 0.6384 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 E24 mock treatment 0.318 0.0437 0.46 0.243 0.00541 0.06 0.3702 0.7989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F01 compound treatment 0.209 -0.0653 -0.69 0.184 -0.0536 -0.64 -0.9385 -0.9994 3041047 ChemDiv3_014895 COc1ccc(cc1)N(C(=O)c2ccncc2)S(=O)(=O)c3ccc(OC)c(OC)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F02 compound treatment 1.161 0.887 9.31 1.067 0.829 9.92 13.6019 0.9995 3123754 ChemDiv3_014896 CC1CC(=O)c2cnc(Nc3ccccc3)nc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F03 compound treatment 0.305 0.0307 0.32 0.31 0.0724 0.87 0.8405 0.9093 3041048 ChemDiv3_014897 CCC(=O)N(CCC1(CCOC(C)(C)C1)c2ccccc2)Cc3ccccc3F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F04 compound treatment 0.082 -0.192 -2.02 0.073 -0.165 -1.97 -2.8207 -0.9999 1039621 ChemDiv3_014898 COc1ccc(CNc2ccccn2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F05 compound treatment 0.2 -0.0743 -0.78 0.212 -0.0256 -0.31 -0.7684 -0.9165 1464156 ChemDiv3_014899 CCN(CC)CC(O)Cn1ccc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F06 compound treatment 0.138 -0.136 -1.43 0.134 -0.104 -1.24 -1.8887 -0.9974 3041049 ChemDiv3_014900 C(Sc1nc2ccccc2[nH]1)c3cc(no3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F07 compound treatment 0.345 0.0707 0.74 0.245 0.00741 0.09 0.5876 0.7859 3123755 ChemDiv3_014901 CCc1ccccc1NC(=O)CSc2nc3cccnc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F08 compound treatment 0.472 0.198 2.08 0.363 0.125 1.5 2.5291 0.9873 3123756 ChemDiv3_014902 Oc1cccc(NC(=O)C2CC(=NO2)c3cccc(Br)c3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F09 compound treatment 0.467 0.193 2.02 0.436 0.198 2.37 3.1095 0.9968 3041050 ChemDiv3_014903 COc1ccc(Cc2nc(c(NCc3ccccc3)o2)S(=O)(=O)c4ccc(C)cc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F10 compound treatment 0.483 0.209 2.19 0.352 0.114 1.37 2.5177 0.9743 3123757 ChemDiv3_014904 COc1ccc(cc1OC)C2CC(n3ncc(C(=O)NCC4CCCO4)c3N2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F11 compound treatment 0.277 0.00269 0.03 0.256 0.0184 0.22 0.1757 0.7913 3041051 ChemDiv3_014905 O=C(Nc1ccccc1)C2CC(=O)N=C(N2)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F12 compound treatment 0.905 0.631 6.62 0.767 0.529 6.33 9.1627 0.9997 3123758 ChemDiv3_014906 COc1ccc(cc1)C2CC(=O)c3cnc(Nc4ccccc4OC)nc3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F13 compound treatment 0.73 0.456 4.79 0.642 0.404 4.84 6.8055 1.0 3041107 ChemDiv3_014907 CC1=CC(C)(C)N(C(=O)c2ccc(F)cc2)c3cc4OCOc4cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F14 compound treatment 0.111 -0.163 -1.72 0.094 -0.144 -1.72 -2.4277 -1.0 3041108 ChemDiv3_014908 Cc1ccc2[nH]c(NCc3ccccc3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F15 compound treatment 0.25 -0.0243 -0.26 0.167 -0.0706 -0.84 -0.7778 -0.8815 3041109 ChemDiv3_014909 Fc1ccc(CNCc2ccccn2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F16 compound treatment 0.277 0.00269 0.03 0.227 -0.0106 -0.13 -0.0697 -0.5365 3041110 ChemDiv3_014910 Fc1ccc(CNC(=O)C2CC(=O)NC3=C2C(=O)CCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F17 compound treatment 0.097 -0.177 -1.86 0.089 -0.149 -1.78 -2.5739 -0.9997 3041111 ChemDiv3_014911 C(Nc1ccc2n(cnc2c1)c3ccccc3)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F18 compound treatment 0.707 0.433 4.54 0.487 0.249 2.98 5.3234 0.9792 3041112 ChemDiv3_014912 Cc1[nH]c2ccccc2c1C3(O)C(=O)N(CCc4ccccc4)c5ccc(Br)cc53 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F19 compound treatment 0.115 -0.159 -1.67 0.1 -0.138 -1.65 -2.3472 -1.0 3041113 ChemDiv3_014913 CCn1cnc2cc(NC(=O)c3cc(OC)c(OC)c(OC)c3)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F20 compound treatment 0.362 0.0877 0.92 0.345 0.107 1.29 1.5599 0.9867 3041114 ChemDiv3_014914 NC(=O)CS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F21 compound treatment 0.747 0.473 4.96 0.709 0.471 5.64 7.4986 0.998 3123759 ChemDiv3_014915 CCOC(=O)c1ccc(OCc2nc(no2)c3ccc(OC)c(OC)c3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F22 compound treatment 0.312 0.0377 0.4 0.242 0.00441 0.05 0.3172 0.7943 3123760 ChemDiv3_014916 CN1CCC=C(Cc2n[nH]c(=O)c3ccccc23)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F23 mock treatment 0.329 0.0547 0.57 0.237 -5.94E-4 -0.01 0.4011 0.6983 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 F24 mock treatment 0.254 -0.0203 -0.21 0.224 -0.0136 -0.16 -0.2659 -0.991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G01 compound treatment 0.285 0.0107 0.11 0.221 -0.0166 -0.2 -0.061 -0.2675 3041115 ChemDiv3_014917 CCOC(=O)c1cnc(SCC(=O)Nc2ccc(C)cc2Cl)nc1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G02 compound treatment 0.134 -0.14 -1.47 0.119 -0.119 -1.42 -2.0454 -0.9998 1620450 ChemDiv3_014918 Cc1nc2ccccc2c(O)c1CN3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G03 compound treatment 0.144 -0.13 -1.37 0.106 -0.132 -1.57 -2.0811 -0.9976 3123761 ChemDiv3_014919 O=S(=O)(NCC1CCCO1)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G04 compound treatment 0.041 -0.233 -2.45 0.04 -0.198 -2.36 -3.4044 -0.9998 1718007 ChemDiv3_014920 O=C(CCN1CCC(C1)c2ccccc2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G05 compound treatment 0.113 -0.161 -1.69 0.098 -0.14 -1.67 -2.379 -1.0 3123875 ChemDiv3_014921 O=c1oc2c3CN(COc3ccc2c4CCCc41)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G06 compound treatment 0.258 -0.0163 -0.17 0.209 -0.0286 -0.34 -0.3631 -0.9489 3041116 ChemDiv3_014922 CC1(C)Cc2ccccc2/C(=C/C(=O)Nc3ccccc3)/N1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G07 compound treatment 0.196 -0.0783 -0.82 0.18 -0.0576 -0.69 -1.0688 -0.9961 3123876 ChemDiv3_014923 Clc1ccc(cc1)c2cc([nH]n2)C(=O)NC3CCCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G08 compound treatment 0.955 0.681 7.15 0.864 0.626 7.49 10.3546 0.9997 1412621 ChemDiv3_014924 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)Nc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G09 compound treatment 0.388 0.114 1.19 0.368 0.13 1.56 1.9476 0.9913 3041117 ChemDiv3_014925 CCCCN(C)C(=O)c1cc(n[nH]1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G10 compound treatment 0.282 0.00769 0.08 0.211 -0.0266 -0.32 -0.1679 -0.5115 3041118 ChemDiv3_014926 CC(=O)Nc1ccc(cc1)c2c[nH]cn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G11 compound treatment 0.362 0.0877 0.92 0.334 0.0964 1.15 1.4668 0.9938 3123877 ChemDiv3_014927 Clc1ccc(COC(=O)CCCC2=NS(=O)(=O)c3ccccc3N2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G12 compound treatment 0.353 0.0787 0.83 0.282 0.0444 0.53 0.9601 0.9772 3041119 ChemDiv3_014928 CCc1c(C)[nH]c2c(C#N)cnn2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G13 compound treatment 0.327 0.0527 0.55 0.251 0.0134 0.16 0.5047 0.876 1528570 ChemDiv3_014929 COc1cc(CCN(C)C)c2ccc3cc(OC)c(OC)cc3c2c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G14 compound treatment 0.179 -0.0953 -1.0 0.151 -0.0866 -1.04 -1.4404 -0.9999 3041120 ChemDiv3_014930 CC(C)(C)NCc1nc(no1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G15 compound treatment 0.49 0.216 2.27 0.357 0.119 1.43 2.612 0.9753 1218570 ChemDiv3_014931 COc1ccc(cc1)C2CNC(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G16 compound treatment 0.736 0.462 4.85 0.642 0.404 4.84 6.8501 1.0 3123878 ChemDiv3_014932 CC1(C)CC(=O)c2cnc(NCCc3ccccc3)nc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G17 compound treatment 0.314 0.0397 0.42 0.298 0.0604 0.72 0.8058 0.9658 3041121 ChemDiv3_014933 O=C(NCCc1nc2ccccc2[nH]1)/C=C/c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G18 compound treatment 0.077 -0.197 -2.07 0.07 -0.168 -2.01 -2.8832 -0.9999 3123879 ChemDiv3_014934 Cc1cc(C)c(C#N)c(SCCC(=O)Nc2nc(ns2)c3ccccc3)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G19 compound treatment 0.308 0.0337 0.35 0.222 -0.0156 -0.19 0.1183 0.2956 1238404 ChemDiv3_014935 CC(=O)Nc1c(nc2cc(C)ccn12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G20 compound treatment 0.28 0.00569 0.06 0.23 -0.00759 -0.09 -0.022 -0.2024 3123880 ChemDiv3_014936 Cn1nc(C(=O)NC2CCCCC2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G21 compound treatment 0.28 0.00569 0.06 0.235 -0.00259 -0.03 0.0203 0.3015 1458918 ChemDiv3_014937 CC(O)Cn1c(=N)n(C)c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G22 compound treatment 0.611 0.337 3.54 0.55 0.312 3.74 5.1434 0.9996 3123881 ChemDiv3_014938 OC(=O)C1CCCN(C1)c2c(c3ccccc3)c4cc(Cl)ccc4[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G23 mock treatment 0.298 0.0237 0.25 0.228 -0.00959 -0.11 0.0948 0.3458 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 G24 mock treatment 0.265 -0.00931 -0.1 0.254 0.0164 0.2 0.0696 0.3175 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H01 compound treatment 0.304 0.0297 0.31 0.3 0.0624 0.75 0.7484 0.925 3041122 ChemDiv3_014939 CCOC(=O)c1cccc(Nc2nc(C)cc(C)n2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H02 compound treatment 1.35 1.08 11.3 1.324 1.09 13.0 17.1798 0.9976 3123882 ChemDiv3_014940 CC1CC(=O)c2cnc(nc2C1)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H03 compound treatment 0.158 -0.116 -1.22 0.15 -0.0876 -1.05 -1.6049 -0.9971 3041123 ChemDiv3_014941 Oc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H04 compound treatment 0.121 -0.153 -1.61 0.1 -0.138 -1.65 -2.3026 -0.9999 3123883 ChemDiv3_014942 CC1(C)CN=C(NCc2cccnc2)S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H05 compound treatment 0.368 0.0937 0.98 0.367 0.129 1.55 1.7906 0.9761 3123884 ChemDiv3_014943 COc1ccc(cc1)C2=NNC(=O)c3ccccc3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H06 compound treatment 0.304 0.0297 0.31 0.245 0.00741 0.09 0.2831 0.8735 3041124 ChemDiv3_014944 Cc1cn(CCC(=O)O)c(=O)[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H07 compound treatment 0.291 0.0167 0.18 0.254 0.0164 0.2 0.2627 0.9984 3123885 ChemDiv3_014945 CS(=O)(=O)N1CC(=O)Nc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H08 compound treatment 0.328 0.0537 0.56 0.333 0.0954 1.14 1.2059 0.9471 3041125 ChemDiv3_014946 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3cccc(Br)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H09 compound treatment 0.374 0.0997 1.05 0.281 0.0434 0.52 1.1076 0.9477 3123886 ChemDiv3_014947 O=S(=O)(c1nc(oc1NCc2ccccc2)c3cccs3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H10 compound treatment 0.322 0.0477 0.5 0.251 0.0134 0.16 0.4676 0.8891 3123887 ChemDiv3_014948 O=C(Nc1ccc(cc1)N2C(=O)c3cccnc3C2=O)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H11 compound treatment 0.39 0.116 1.22 0.311 0.0734 0.88 1.4802 0.9873 3041126 ChemDiv3_014949 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CN4CCN(CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H12 compound treatment 1.008 0.734 7.71 0.983 0.745 8.92 11.755 0.9973 3123888 ChemDiv3_014950 O=C1CC(CC2=C1C=Nc3ccccc3N2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H13 compound treatment 0.624 0.35 3.67 0.615 0.377 4.52 5.7899 0.9947 3123889 ChemDiv3_014951 CCCN1C(=O)C(O)(CC(=O)c2ccc(OC)cc2OC)c3cc(Br)ccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H14 compound treatment 0.1 -0.174 -1.83 0.107 -0.131 -1.56 -2.3994 -0.9969 3041127 ChemDiv3_014952 COc1ccc2[nH]c(NCc3ccccc3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H15 compound treatment 0.277 0.00269 0.03 0.271 0.0334 0.4 0.3026 0.7552 3123890 ChemDiv3_014953 Cc1cc(C)cc(c1)N2C(=O)CC(C2=O)n3ccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H16 compound treatment 0.319 0.0447 0.47 0.256 0.0184 0.22 0.4876 0.9405 3041128 ChemDiv3_014954 CCN(CC)C(=O)c1csc(Nc2ccc(OC)cc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H17 compound treatment 0.209 -0.0653 -0.69 0.161 -0.0766 -0.92 -1.133 -0.9898 3123891 ChemDiv3_014955 Cn1c(CN2CCOCC2)nc3cc(NS(=O)(=O)c4ccc(F)cc4)ccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H18 compound treatment 0.356 0.0817 0.86 0.292 0.0544 0.65 1.0669 0.9907 3041129 ChemDiv3_014956 OC(=O)c1cc(NCc2ccccc2)ccc1N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H19 compound treatment 0.531 0.257 2.7 0.509 0.271 3.25 4.2024 0.9957 3123892 ChemDiv3_014957 COc1ccc(cc1)n2cnc3cc(NC(=O)c4cccs4)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H20 compound treatment 0.727 0.453 4.75 0.626 0.388 4.65 6.6479 0.9999 3041130 ChemDiv3_014958 Cc1cc(c2noc(n2)c3ccccc3C)c4ccccc4n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H21 compound treatment 0.307 0.0327 0.34 0.248 0.0104 0.12 0.3308 0.9058 3123893 ChemDiv3_014959 OC1=CONN1c2cccc3ncccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H22 compound treatment 0.341 0.0667 0.7 0.247 0.00941 0.11 0.5748 0.8103 3123894 ChemDiv3_014960 COc1ccc(CNC(=O)c2cn(C)c(=O)c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H23 mock treatment 0.273 -0.00131 -0.01 0.227 -0.0106 -0.13 -0.0994 -0.7794 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 H24 mock treatment 0.26 -0.0143 -0.15 0.205 -0.0326 -0.39 -0.382 -0.9141 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I01 compound treatment 0.221 -0.0533 -0.56 0.178 -0.0596 -0.71 -0.9001 -0.9928 3041131 ChemDiv3_014961 Cc1ccc2n(C)c3c(=O)n(c4ccccc4)c(=O)n(CC(=O)c5ccccc5)c3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I02 compound treatment 0.169 -0.105 -1.11 0.13 -0.108 -1.29 -1.6924 -0.9971 3123895 ChemDiv3_014962 Cc1cc(C)nc(NC(=N)NCc2ccccc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I03 compound treatment 0.657 0.383 4.02 0.711 0.473 5.66 6.8471 0.9859 3123896 ChemDiv3_014963 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I04 compound treatment 0.286 0.0117 0.12 0.262 0.0244 0.29 0.2933 0.9259 3041132 ChemDiv3_014964 CC1(CNC(=O)C1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I05 compound treatment 0.285 0.0107 0.11 0.252 0.0144 0.17 0.2012 0.9784 3123897 ChemDiv3_014965 CCOC(=O)C1=C(CN2CC(C)CC(C)C2)NC(=O)NC1c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I06 compound treatment 0.143 -0.131 -1.38 0.144 -0.0936 -1.12 -1.767 -0.9947 3041133 ChemDiv3_014966 CC1CCN(CC1)C(=N)Nc2nc(C)cc(C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I07 compound treatment 0.397 0.123 1.29 0.33 0.0924 1.11 1.6929 0.9971 3123898 ChemDiv3_014967 Cc1ccsc1CCNC(=O)c2cc(n[nH]2)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I08 compound treatment 0.63 0.356 3.74 0.558 0.32 3.83 5.3522 0.9999 1144393 ChemDiv3_014968 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I09 compound treatment 0.393 0.119 1.25 0.313 0.0754 0.9 1.5194 0.9874 3123899 ChemDiv3_014969 O=C(NCc1ccccc1)c2cc(n[nH]2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I10 compound treatment 0.831 0.557 5.85 0.786 0.548 6.56 8.7738 0.9983 3123900 ChemDiv3_014970 COc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccccc4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I11 compound treatment 0.441 0.167 1.75 0.31 0.0724 0.87 1.8505 0.9474 3041134 ChemDiv3_014971 Cc1ccccc1COC(=O)CCCC2=NS(=O)(=O)c3ccccc3N2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I12 compound treatment 0.175 -0.0993 -1.04 0.164 -0.0736 -0.88 -1.3602 -0.9964 3123901 ChemDiv3_014972 CN(C1CCCCC1)C(=N)Nc2nc(C)cc(C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I13 compound treatment 0.188 -0.0863 -0.91 0.163 -0.0746 -0.89 -1.2721 -1.0 1922882 ChemDiv3_014973 Cc1ccc(O)c(c1)C2=Nc3ccccc3C2(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I14 compound treatment 1.341 1.07 11.2 1.281 1.04 12.48 16.7491 0.9985 3041136 ChemDiv3_014974 COc1ccc(NCc2nc(no2)c3ccccc3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I15 compound treatment 0.26 -0.0143 -0.15 0.229 -0.00859 -0.1 -0.179 -0.9828 1555304 ChemDiv3_014975 CNC(=O)Nc1cc(no1)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I16 compound treatment 0.325 0.0507 0.53 0.252 0.0144 0.17 0.4983 0.8905 3041137 ChemDiv3_014976 COc1ccc2c(C)nc(O)cc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I17 compound treatment 0.393 0.119 1.25 0.318 0.0804 0.96 1.5617 0.9918 1919870 ChemDiv3_014977 CNC(=O)NC1CCCCc2sccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I18 compound treatment 0.438 0.164 1.72 0.33 0.0924 1.11 1.9974 0.9772 3124156 ChemDiv3_014978 Cn1cc(C2CC(=O)N(C2=O)c3ccc(O)cc3)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I19 compound treatment 0.852 0.578 6.07 0.68 0.442 5.29 8.033 0.9977 1511504 ChemDiv3_014979 O=C1CCCc2nc(sc12)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I20 compound treatment 0.321 0.0467 0.49 0.253 0.0154 0.18 0.4771 0.9107 3040062 ChemDiv3_014980 COc1cccc(c1)C2N(CCCN(C)C)C(=O)c3oc4ccc(C)cc4c(=O)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I21 compound treatment 0.319 0.0447 0.47 0.262 0.0244 0.29 0.5384 0.9739 1483465 ChemDiv3_014981 CCc1ccc(cc1)C(=O)Cn2c(NCCO)nc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I22 compound treatment 1.111 0.837 8.79 1.019 0.781 9.35 12.8245 0.9995 3040063 ChemDiv3_014982 Cc1cc(C)n(n1)c2nc(nc3CC(C)(C)OCc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I23 mock treatment 0.232 -0.0423 -0.44 0.234 -0.00359 -0.04 -0.3446 -0.7719 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 I24 mock treatment 0.291 0.0167 0.18 0.251 0.0134 0.16 0.2373 0.999 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J01 compound treatment 0.2 -0.0743 -0.78 0.191 -0.0466 -0.56 -0.9461 -0.9864 3040065 ChemDiv3_014983 CC(C)COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J02 compound treatment 1.294 1.02 10.71 1.242 1.0 12.02 16.0701 0.9983 3040067 ChemDiv3_014984 CC1CC(=O)c2c(C)nc(NCc3ccco3)nc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J03 compound treatment 0.324 0.0497 0.52 0.279 0.0414 0.5 0.7193 0.9997 3040068 ChemDiv3_014985 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J04 compound treatment 0.409 0.135 1.41 0.445 0.207 2.48 2.7549 0.9645 3040069 ChemDiv3_014986 COc1oc(nc1C(F)(F)F)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J05 compound treatment 0.341 0.0667 0.7 0.297 0.0594 0.71 0.9978 1.0 3124016 ChemDiv3_014987 Cc1cc(C)cc(CC2CC(=O)N(CC(=O)O)C2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J06 compound treatment 0.289 0.0147 0.15 0.236 -0.00159 -0.02 0.0956 0.615 3040071 ChemDiv3_014988 C[C@H]1C(O[C@@H]2C(OC(=O)C)C(=O)OC12)n3ccc(=O)[nH]c3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J07 compound treatment 1.16 0.886 9.3 1.147 0.909 10.88 14.2713 0.997 3124017 ChemDiv3_014989 Cc1cccc(c1)C(=O)c2c([nH]c(=O)c3ccccc23)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J08 compound treatment 0.4 0.126 1.32 0.355 0.117 1.4 1.9267 0.9995 3124018 ChemDiv3_014990 CSc1ccccc1NC(=O)C2CC(=NO2)c3cccc(Br)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J09 compound treatment 0.159 -0.115 -1.21 0.136 -0.102 -1.22 -1.7159 -1.0 3040073 ChemDiv3_014991 Cc1nc2ccccc2n1C/C=C/c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J10 compound treatment 0.685 0.411 4.31 0.633 0.395 4.73 6.3952 0.9989 3124019 ChemDiv3_014992 COc1cccc2C(CC(=O)c3ccc(F)cc3)C4=C(CC(C)(C)CC4=O)Oc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J11 compound treatment 0.488 0.214 2.24 0.439 0.201 2.41 3.2909 0.9994 3040075 ChemDiv3_014993 CSc1ccccc1NC2=NS(=O)(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J12 compound treatment 0.118 -0.156 -1.64 0.103 -0.135 -1.61 -2.2995 -1.0 3124020 ChemDiv3_014994 CCN1CCN(CC1)c2ncc3C(=O)CC(Cc3n2)c4cc(OC)c(OC)c(OC)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J13 compound treatment 0.281 0.00669 0.07 0.212 -0.0256 -0.31 -0.1669 -0.5311 3040077 ChemDiv3_014995 Cn1c(CN2CCOCC2)nnc1SCc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J14 compound treatment 0.308 0.0337 0.35 0.281 0.0434 0.52 0.6174 0.9825 3124021 ChemDiv3_014996 FC(F)(F)c1nc2[nH]c(cc(=O)n2n1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J15 compound treatment 0.691 0.417 4.38 0.603 0.365 4.37 6.1859 1.0 3040079 ChemDiv3_014997 Fc1ccccc1N2C(=O)Cn3c2nc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J16 compound treatment 0.141 -0.133 -1.4 0.128 -0.11 -1.31 -1.9172 -0.9995 3124022 ChemDiv3_014998 Cn1c(cn2cc(nc12)c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J17 compound treatment 0.3 0.0257 0.27 0.237 -5.94E-4 -0.01 0.1857 0.6882 3040081 ChemDiv3_014999 CCn1c(NCc2ccccn2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J18 compound treatment 0.39 0.116 1.22 0.306 0.0684 0.82 1.4379 0.9815 3124023 ChemDiv3_015000 COc1cc2CCN(C(c3ccccc3)c2cc1OC)C(=O)CSc4nc5ccccc5o4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J19 compound treatment 0.294 0.0197 0.21 0.19 -0.0476 -0.57 -0.2564 -0.4233 3040082 ChemDiv3_015001 COc1ccccc1OCCn2c(N)nc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J20 compound treatment 0.313 0.0387 0.41 0.242 0.00441 0.05 0.3246 0.7922 3124024 ChemDiv3_015002 COC(=O)c1ccc(cc1)c2nc(no2)c3cc(C)nc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J21 compound treatment 0.303 0.0287 0.3 0.27 0.0324 0.39 0.4872 0.9922 1874332 ChemDiv3_015003 O=C(Nc1cnc2ccccn2c1=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J22 compound treatment 0.284 0.00969 0.1 0.233 -0.00459 -0.05 0.0331 0.2861 3124025 ChemDiv3_015004 CN(C(=O)c1cn(C)c(=O)c2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J23 mock treatment 0.295 0.0207 0.22 0.253 0.0154 0.18 0.284 0.9967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 J24 mock treatment 0.224 -0.0503 -0.53 0.207 -0.0306 -0.37 -0.6325 -0.9839 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K01 compound treatment 0.233 -0.0413 -0.43 0.194 -0.0436 -0.52 -0.6756 -0.9958 3124026 ChemDiv3_015005 Fc1ccccc1N/C=C/2\C(=O)c3ccccc3N(Cc4ccc(Cl)cc4)S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K02 compound treatment 0.247 -0.0273 -0.29 0.184 -0.0536 -0.64 -0.6562 -0.9342 1232514 ChemDiv3_015006 CC(C)CC(=O)CC1(O)C(=O)Nc2ccccc21 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K03 compound treatment 0.421 0.147 1.54 0.476 0.238 2.85 3.1063 0.9582 3124027 ChemDiv3_015007 CSc1cccc(NS(=O)(=O)c2ccc(cc2)n3cccn3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K04 compound treatment 0.208 -0.0663 -0.7 0.159 -0.0786 -0.94 -1.1574 -0.9891 3040086 ChemDiv3_015008 O=C1CC(=Nc2ccccc2N1)/C=C/c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K05 compound treatment 0.427 0.153 1.6 0.382 0.144 1.73 2.3556 0.9993 3124028 ChemDiv3_015009 CCOC(=O)C1=C(CN(C)c2ccccc2)NC(=O)NC1c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K06 compound treatment 0.409 0.135 1.41 0.348 0.11 1.32 1.9343 0.9994 3040088 ChemDiv3_015010 CN(C)CCCNc1c2CCCc2nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K07 compound treatment 0.456 0.182 1.91 0.43 0.192 2.3 2.9771 0.9957 3040152 ChemDiv3_015011 COc1ccc(C)cc1NC(=O)c2cc(n[nH]2)C3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K08 compound treatment 0.562 0.288 3.02 0.58 0.342 4.1 5.0333 0.9888 1461241 ChemDiv3_015012 CCN(C(=O)C1Cc2ccccc2CN1S(=O)(=O)c3ccc(F)cc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K09 compound treatment 0.325 0.0507 0.53 0.3 0.0624 0.75 0.9044 0.9863 3040154 ChemDiv3_015013 CCN(CC)C(=O)c1cc(n[nH]1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K10 compound treatment 0.308 0.0337 0.35 0.206 -0.0316 -0.38 -0.0171 -0.033 3040155 ChemDiv3_015014 Cc1cc(C)nc(NC2=NCCN2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K11 compound treatment 0.309 0.0347 0.36 0.331 0.0934 1.12 1.0478 0.8914 3040157 ChemDiv3_015015 Cc1ccccc1C2Nc3ccccc3S(=O)(=O)N2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K12 compound treatment 0.322 0.0477 0.5 0.253 0.0154 0.18 0.4845 0.9078 1663841 ChemDiv3_015016 CCOC(=O)c1cnc2ccc(cc2c1NCCN(C)C)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K13 compound treatment 0.231 -0.0433 -0.45 0.242 0.00441 0.05 -0.2844 -0.621 1496276 ChemDiv3_015017 O=C1N(CCC2=NCCc3ccccc23)C(=O)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K14 compound treatment 0.391 0.117 1.23 0.283 0.0454 0.54 1.2507 0.933 3040159 ChemDiv3_015018 NC(=O)CCn1nc(c2ccccc2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K15 compound treatment 0.315 0.0407 0.43 0.242 0.00441 0.05 0.3394 0.7884 3040160 ChemDiv3_015019 COCc1cc(C)[nH]c(=O)c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K16 compound treatment 0.375 0.101 1.06 0.336 0.0984 1.18 1.5803 0.9986 3124029 ChemDiv3_015020 Cc1n[nH]c2NC(=O)CC(c12)c3ccc4ccccc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K17 compound treatment 0.54 0.266 2.79 0.344 0.106 1.27 2.8733 0.9368 3040162 ChemDiv3_015021 CCC1(CC)Cc2ccccc2C(=O)N1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K18 compound treatment 0.422 0.148 1.55 0.327 0.0894 1.07 1.8532 0.9835 1313313 ChemDiv3_015022 Cc1nc(C)c2c(=O)cc([nH]c2n1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K19 compound treatment 0.145 -0.129 -1.36 0.121 -0.117 -1.39 -1.9467 -0.9999 1189980 ChemDiv3_015023 Fc1ccc(Cc2nc3ccccc3[nH]2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K20 compound treatment 0.357 0.0827 0.87 0.258 0.0204 0.24 0.7867 0.8721 3124030 ChemDiv3_015024 COC(=O)c1ccc(cc1)C2N(CCCN(C)C)C(=O)c3oc4ccc(F)cc4c(=O)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K21 compound treatment 0.293 0.0187 0.2 0.192 -0.0456 -0.55 -0.2469 -0.426 1271487 ChemDiv3_015025 CCCCn1c(=N)n(CC(=O)OC)c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K22 compound treatment 0.335 0.0607 0.64 0.242 0.00441 0.05 0.488 0.763 3124031 ChemDiv3_015026 COc1ccc(cc1)C2(CNC(=O)CCC(=O)O)CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K23 mock treatment 0.222 -0.0523 -0.55 0.189 -0.0486 -0.58 -0.7996 -0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 K24 mock treatment 0.214 -0.0603 -0.63 0.227 -0.0106 -0.13 -0.5375 -0.8321 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L01 compound treatment 0.198 -0.0763 -0.8 0.197 -0.0406 -0.49 -0.9102 -0.9712 3040165 ChemDiv3_015027 Cc1cc(C)nc(NCCCN2CCOCC2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L02 compound treatment 0.525 0.251 2.63 0.514 0.276 3.31 4.2002 0.9936 3124032 ChemDiv3_015028 Clc1ccc(SCc2cc(=O)c3c(=O)n([nH]c3[nH]2)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L03 compound treatment 0.257 -0.0173 -0.18 0.219 -0.0186 -0.22 -0.2859 -0.995 3040167 ChemDiv3_015029 Cn1c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L04 compound treatment 0.224 -0.0503 -0.53 0.19 -0.0476 -0.57 -0.7763 -0.9993 3124033 ChemDiv3_015030 OC(=O)c1ccc(NCc2cccnc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L05 compound treatment 0.56 0.286 3.0 0.591 0.353 4.23 5.1115 0.9859 3124034 ChemDiv3_015031 Fc1cnc(nc1N2CCc3ccccc23)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L06 compound treatment 0.291 0.0167 0.18 0.233 -0.00459 -0.05 0.0851 0.4631 3040169 ChemDiv3_015032 Clc1ccc(Cn2ccc(nc2=O)N3CCOCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L07 compound treatment 0.343 0.0687 0.72 0.3 0.0624 0.75 1.0381 0.9999 3124035 ChemDiv3_015033 COc1ccc(NC(c2ccccn2)c3oc(CO)cc(=O)c3O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L08 compound treatment 0.249 -0.0253 -0.27 0.196 -0.0416 -0.5 -0.5399 -0.9569 3040171 ChemDiv3_015034 Cc1cc(NC(=O)C2CC(=NO2)c3ccc(Cl)cc3)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L09 compound treatment 0.318 0.0437 0.46 0.245 0.00741 0.09 0.3871 0.8284 3124036 ChemDiv3_015035 Fc1ccc(cc1)C(=O)NCCCc2nc3ccccc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L10 compound treatment 0.287 0.0127 0.13 0.247 0.00941 0.11 0.1738 0.9965 3040173 ChemDiv3_015036 N1N=C(c2ccncc2)c3ccccc3N=C1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L11 compound treatment 0.482 0.208 2.18 0.464 0.226 2.71 3.4578 0.9942 3124037 ChemDiv3_015037 O=C(CC1Nc2cccc3cccc(NC1=O)c23)Nc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L12 compound treatment 0.374 0.0997 1.05 0.295 0.0574 0.69 1.226 0.9791 3124038 ChemDiv3_015038 Cc1nc2[nH]c(CSc3ccc(Cl)cc3)cc(=O)n2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L13 compound treatment 0.309 0.0347 0.36 0.268 0.0304 0.36 0.5148 1.0 1308709 ChemDiv3_015039 Cc1nc(c(CC(=O)O)s1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L14 compound treatment 0.287 0.0127 0.13 0.222 -0.0156 -0.19 -0.0377 -0.1644 3124039 ChemDiv3_015040 COc1ccc(cc1)C2CC(=O)c3cnn(c4nc5ccccc5s4)c3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L15 compound treatment 0.335 0.0607 0.64 0.274 0.0364 0.44 0.7587 0.9828 3040237 ChemDiv3_015041 COc1cc(CO)ccc1Oc2nnnn2c3ccc(cc3)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L16 compound treatment 0.325 0.0507 0.53 0.257 0.0194 0.23 0.5406 0.9308 3040238 ChemDiv3_015042 Cn1c(cn2cc(nc12)c3ccc(Br)cc3)c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L17 compound treatment 0.294 0.0197 0.21 0.294 0.0564 0.67 0.6234 0.8832 3040240 ChemDiv3_015043 CCCCn1c(NCc2ccccn2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L18 compound treatment 0.529 0.255 2.67 0.4 0.162 1.94 3.2654 0.9877 1524459 ChemDiv3_015044 OC(=O)CSCC(=O)N1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L19 compound treatment 0.254 -0.0203 -0.21 0.222 -0.0156 -0.19 -0.2828 -0.9978 3040242 ChemDiv3_015045 COc1ccccc1OCCn2c(CO)nc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L20 compound treatment 0.297 0.0227 0.24 0.256 0.0184 0.22 0.3242 0.9992 3040243 ChemDiv3_015046 CCc1nc(c(C#N)cc1C)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L21 compound treatment 0.61 0.336 3.53 0.442 0.204 2.45 4.2223 0.984 3040245 ChemDiv3_015047 Cc1sc2nc(SCc3nc(no3)c4cccs4)n(c5ccccc5)c(=O)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L22 compound treatment 1.153 0.879 9.23 1.211 0.973 11.65 14.7607 0.9934 3124040 ChemDiv3_015048 CCOC(=O)c1cn(C)c(=O)c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L23 mock treatment 0.251 -0.0233 -0.24 0.206 -0.0316 -0.38 -0.4404 -0.9779 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 L24 mock treatment 0.243 -0.0313 -0.33 0.221 -0.0166 -0.2 -0.3729 -0.9708 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M01 compound treatment 0.374 0.0997 1.05 0.271 0.0334 0.4 1.023 0.9128 3124041 ChemDiv3_015049 Clc1ccc(CN2c3ccccc3C(=O)/C(=C\NCc4ccccc4)/S2(=O)=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M02 compound treatment 0.265 -0.00931 -0.1 0.235 -0.00259 -0.03 -0.0911 -0.8878 1486647 ChemDiv3_015050 Cn1c(Cn2cnc3ccccc23)nc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M03 compound treatment 0.352 0.0777 0.82 0.272 0.0344 0.41 0.868 0.9498 3124042 ChemDiv3_015051 CC(C)c1ccc(NS(=O)(=O)c2ccc(cc2)n3cccn3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M04 compound treatment 0.288 0.0137 0.14 0.238 4.06E-4 0.0 0.1051 0.7306 1054354 ChemDiv3_015052 Cc1cc(O)nc(n1)N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M05 compound treatment 0.396 0.122 1.28 0.312 0.0744 0.89 1.5332 0.9844 3040248 ChemDiv3_015053 CCOC(=O)c1cc(C)n(CC2CCC(CC2)C(=O)N3CCCC3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M06 compound treatment 0.316 0.0417 0.44 0.3 0.0624 0.75 0.8376 0.9677 3124043 ChemDiv3_015054 CCC(=O)NC(C)Cc1c[nH]c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M07 compound treatment 0.417 0.143 1.5 0.411 0.173 2.07 2.5267 0.9873 3124044 ChemDiv3_015055 CCOc1ccc(cc1)c2cc([nH]n2)C(=O)NC(C)c3ccc4OCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M08 compound treatment 0.54 0.266 2.79 0.455 0.217 2.6 3.8124 0.9994 1604600 ChemDiv3_015056 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M09 compound treatment 0.172 -0.102 -1.07 0.15 -0.0876 -1.05 -1.5009 -0.9999 3124157 ChemDiv3_015057 Cc1ccnc(NC(=O)c2cc(n[nH]2)c3ccc(C)c(C)c3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M10 compound treatment 0.26 -0.0143 -0.15 0.242 0.00441 0.05 -0.069 -0.4332 1188380 ChemDiv3_015058 NC(=O)COc1cccc2cccnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M11 compound treatment 0.063 -0.211 -2.22 0.063 -0.175 -2.09 -3.0464 -0.9995 3124158 ChemDiv3_015059 Cc1cccc(C)c1Nc2nn3c(=O)c4ccccc4nc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M12 compound treatment 0.35 0.0757 0.79 0.266 0.0284 0.34 0.8024 0.9282 3040251 ChemDiv3_015060 CN1CCc2c(C1=O)n(CC(O)CN3CCCC3)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M13 compound treatment 0.404 0.13 1.36 0.3 0.0624 0.75 1.4911 0.96 1660192 ChemDiv3_015061 Oc1cccc(c1)C2CC(=O)c3c(N2)ccc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M14 compound treatment 0.253 -0.0213 -0.22 0.183 -0.0546 -0.65 -0.6201 -0.8981 1347735 ChemDiv3_015062 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCCCC2)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M15 compound treatment 0.206 -0.0683 -0.72 0.186 -0.0516 -0.62 -0.9438 -0.9972 1103139 ChemDiv3_015063 Cc1ccc(cc1)c2cn3CCSc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M16 compound treatment 0.299 0.0247 0.26 0.309 0.0714 0.85 0.7874 0.882 3124159 ChemDiv3_015064 CC(Nc1nc2ccccc2n1CC=C)c3cc(Cl)ccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M17 compound treatment 0.324 0.0497 0.52 0.223 -0.0146 -0.17 0.2455 0.4462 1357733 ChemDiv3_015065 CCOc1ccc2[nH]c(NCCO)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M18 compound treatment 0.31 0.0357 0.37 0.207 -0.0306 -0.37 0.0062 0.0118 3040255 ChemDiv3_015066 CCN(c1ccccc1)c2cc(=O)n(C)c(=O)[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M19 compound treatment 0.954 0.68 7.14 0.975 0.737 8.82 11.2863 0.9945 3040193 ChemDiv3_015067 Cc1ccc(cc1)c2cc(on2)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M20 compound treatment 0.432 0.158 1.66 0.34 0.102 1.23 2.0374 0.989 3040107 ChemDiv3_015068 CCN1CCOC(CC(=O)Nc2cccc(OC)c2)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M21 compound treatment 0.317 0.0427 0.45 0.224 -0.0136 -0.16 0.202 0.4236 1581966 ChemDiv3_015069 Cc1ccc2[nH]c(NCCO)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M22 compound treatment 0.401 0.127 1.33 0.345 0.107 1.29 1.8495 0.9998 3040109 ChemDiv3_015070 O=c1[nH][nH]c(=O)c2c(NS(=O)(=O)c3ccccc3)cccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M23 mock treatment 0.252 -0.0223 -0.23 0.204 -0.0336 -0.4 -0.4499 -0.967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 M24 mock treatment 0.251 -0.0233 -0.24 0.239 0.00141 0.02 -0.1612 -0.657 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N01 compound treatment 0.21 -0.0643 -0.68 0.189 -0.0486 -0.58 -0.8887 -0.9972 3040112 ChemDiv3_015071 Cc1cc(C)nc(Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N02 compound treatment 0.282 0.00769 0.08 0.241 0.00341 0.04 0.0859 0.9499 3040113 ChemDiv3_015072 O=c1n([nH]c2[nH]c(CSc3nnnn3c4ccccc4)cc(=O)c12)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N03 compound treatment 0.249 -0.0253 -0.27 0.219 -0.0186 -0.22 -0.3453 -0.9961 3040114 ChemDiv3_015073 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N(C(=O)c4ccncc4)c5ccc(OC)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N04 compound treatment 0.383 0.109 1.14 0.295 0.0574 0.69 1.2928 0.9704 3040117 ChemDiv3_015074 Cc1cc(on1)c2ccccc2C(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N05 compound treatment 0.401 0.127 1.33 0.392 0.154 1.85 2.2471 0.987 1284849 ChemDiv3_015075 O=C1CC(C(=O)N1c2ccccc2)c3c[nH]c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N06 compound treatment 0.358 0.0837 0.88 0.324 0.0864 1.03 1.3525 0.9967 3124160 ChemDiv3_015076 O=C(NCCCn1ccnc1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N07 compound treatment 0.31 0.0357 0.37 0.291 0.0534 0.64 0.7169 0.9677 3040120 ChemDiv3_015077 CC(C)CC(Nc1ncnc2c3ccccc3oc12)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N08 compound treatment 0.094 -0.18 -1.89 0.081 -0.157 -1.87 -2.6639 -1.0 3124161 ChemDiv3_015078 Clc1ccc(cc1)C2=NOC(C2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N09 compound treatment 0.375 0.101 1.06 0.28 0.0424 0.51 1.1065 0.9434 3040123 ChemDiv3_015079 CCOC(=O)c1c(Cc2cccc(C)c2)c[nH]c1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N10 compound treatment 0.315 0.0407 0.43 0.312 0.0744 0.89 0.9317 0.9435 3124162 ChemDiv3_015080 CCc1c(C)nc2SCC(CS(=O)(=O)c3ccc(C)cc3)n2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N11 compound treatment 0.293 0.0187 0.2 0.243 0.00541 0.06 0.1845 0.8929 3040127 ChemDiv3_015081 CCN(CC)C(=O)Cn1c(nc2ccccc12)S(=O)(=O)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N12 compound treatment 0.044 -0.23 -2.42 0.044 -0.194 -2.32 -3.3482 -0.9998 3124163 ChemDiv3_015082 CC1=NN(C(=O)C1Cc2ccccc2)c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N13 compound treatment 0.279 0.00469 0.05 0.249 0.0114 0.14 0.1313 0.9051 3040195 ChemDiv3_015083 CCn1c(SCC(=O)N2CCCCC2)nnc1c3ccccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N14 compound treatment 0.332 0.0577 0.61 0.245 0.00741 0.09 0.4911 0.802 3040197 ChemDiv3_015084 CC(C)c1ccc(cc1)C2CC(=O)c3cnc4c(c(C)nn4c3C2)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N15 compound treatment 0.975 0.701 7.36 0.93 0.692 8.28 11.0615 0.9983 3040198 ChemDiv3_015085 O(c1nnnn1c2ccccc2)c3cccc4cccnc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N16 compound treatment 0.124 -0.15 -1.58 0.105 -0.133 -1.59 -2.2381 -1.0 3040201 ChemDiv3_015086 CCCCn1c(NCc2cccc(Cl)c2)ncc1c3ccc(OCC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N17 compound treatment 0.318 0.0437 0.46 0.253 0.0154 0.18 0.4548 0.9197 3040202 ChemDiv3_015087 C(Nc1nc2ccccc2n1Cc3ccccc3)c4ccncc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N18 compound treatment 0.33 0.0557 0.58 0.245 0.00741 0.09 0.4762 0.8051 3040204 ChemDiv3_015088 Cc1n[nH]c(C)c1Nc2nc(cs2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N19 compound treatment 0.243 -0.0313 -0.33 0.205 -0.0326 -0.39 -0.5083 -0.9964 3124164 ChemDiv3_015089 CC1CCCC(C)N1CC(O)Cn2cc(/C=N/O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N20 compound treatment 0.303 0.0287 0.3 0.284 0.0464 0.56 0.6057 0.9588 1537967 ChemDiv3_015090 Fc1ccc(c(F)c1)n2cc(C(=O)N3CCN(CC3)c4ccccc4)c5ccccc5c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N21 compound treatment 0.374 0.0997 1.05 0.269 0.0314 0.38 1.006 0.9044 3124165 ChemDiv3_015091 O=c1cc(nc(SCc2nc(no2)c3cccs3)[nH]1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N22 compound treatment 0.27 -0.00431 -0.05 0.22 -0.0176 -0.21 -0.1809 -0.84 3040208 ChemDiv3_015092 Cn1cc(C(=O)Nc2cccnc2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N23 mock treatment 0.287 0.0127 0.13 0.203 -0.0346 -0.41 -0.1984 -0.4564 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 N24 mock treatment 0.211 -0.0633 -0.66 0.215 -0.0226 -0.27 -0.6613 -0.9213 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O01 compound treatment 0.845 0.571 5.99 0.807 0.569 6.81 9.0555 0.998 3124166 ChemDiv3_015093 O=S(=O)(NCCC1=CCCCC1)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O02 compound treatment 0.719 0.445 4.67 0.676 0.438 5.25 7.0115 0.9983 1235889 ChemDiv3_015094 COc1ccccc1C(=O)c2nc3ccccc3n2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O03 compound treatment 0.339 0.0647 0.68 0.29 0.0524 0.63 0.9238 0.9992 3124167 ChemDiv3_015095 CC(CNS(=O)(=O)c1ccc(cc1)n2cccn2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O04 compound treatment 0.314 0.0397 0.42 0.224 -0.0136 -0.16 0.1797 0.4017 1613440 ChemDiv3_015096 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O05 compound treatment 0.528 0.254 2.66 0.439 0.201 2.41 3.5879 0.9987 3124168 ChemDiv3_015097 CCOC(=O)c1cc(C)n(CC2CCC(CC2)C(=O)NCc3ccccc3)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O06 compound treatment 0.158 -0.116 -1.22 0.129 -0.109 -1.3 -1.7825 -0.9995 1590447 ChemDiv3_015098 O=C1NCCCC(=C1NCc2ccccc2)C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O07 compound treatment 0.464 0.19 1.99 0.452 0.214 2.57 3.2226 0.9922 3040277 ChemDiv3_015099 O=C(NCCC1=CCCCC1)c2cc(n[nH]2)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O08 compound treatment 0.225 -0.0493 -0.52 0.227 -0.0106 -0.13 -0.4558 -0.8549 3040279 ChemDiv3_015100 CC1(C)CC(CC(=O)O)(CCO1)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O09 compound treatment 0.61 0.336 3.53 0.565 0.327 3.92 5.2629 0.9986 3040282 ChemDiv3_015101 Cc1ccc(cc1C)c2cc([nH]n2)C(=O)Nc3cccc4CCCCc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O10 compound treatment 0.58 0.306 3.21 0.337 0.0994 1.19 3.1112 0.9087 3040284 ChemDiv3_015102 CC(C)CC(=O)/C=C\1/Nc2cc(C)ccc2OC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O11 compound treatment 1.123 0.849 8.91 1.095 0.857 10.26 13.5566 0.9975 3040285 ChemDiv3_015103 COC(=O)c1ccc(CSc2ccc(Br)cc2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O12 compound treatment 1.084 0.81 8.5 1.117 0.879 10.52 13.4531 0.9944 3040287 ChemDiv3_015104 CCn1c2C(=O)CCCc2c3ccc(OC)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O13 compound treatment 0.36 0.0857 0.9 0.367 0.129 1.55 1.7312 0.9667 1486519 ChemDiv3_015105 CCn1cc(C(=O)N(Cc2ccco2)Cc3ccc(cc3)N(C)C)c(=O)c4ccc(C)nc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O14 compound treatment 0.375 0.101 1.06 0.353 0.115 1.38 1.7241 0.9913 3124169 ChemDiv3_015106 CC1CN/C(=C/C(=O)c2ccccc2)/C(=O)N1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O15 compound treatment 1.075 0.801 8.41 1.035 0.797 9.54 12.6925 0.998 1708643 ChemDiv3_015107 Nc1ccc(cc1)C(=O)Nc2nc3ccccc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O16 compound treatment 0.116 -0.158 -1.66 0.112 -0.126 -1.5 -2.2382 -0.9987 3124170 ChemDiv3_015108 Cc1ccnc(NCc2ccc(Br)cc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O17 compound treatment 0.228 -0.0463 -0.49 0.183 -0.0546 -0.65 -0.8058 -0.9895 3040293 ChemDiv3_015109 CCCN1C2=NCCCN2c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O18 compound treatment 0.503 0.229 2.4 0.411 0.173 2.07 3.1654 0.9973 3124171 ChemDiv3_015110 COC(=O)CC1=Nc2ccccc2NC(=O)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O19 compound treatment 0.19 -0.0843 -0.89 0.174 -0.0636 -0.76 -1.1642 -0.9971 1783629 ChemDiv3_015111 COc1cc2cc(C)nc(C)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O20 compound treatment 0.299 0.0247 0.26 0.21 -0.0276 -0.33 -0.0501 -0.1194 3124172 ChemDiv3_015112 CCN1CCOC(CC(=O)Nc2ccccc2C)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O21 compound treatment 0.129 -0.145 -1.53 0.114 -0.124 -1.48 -2.1248 -0.9999 1254074 ChemDiv3_015113 Cc1nc2ccccc2n1CCOc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O22 compound treatment 0.162 -0.112 -1.18 0.14 -0.0976 -1.17 -1.6597 -1.0 3040803 ChemDiv3_015114 CCN(CC)c1ccc(Nc2nc(cs2)c3cccs3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O23 mock treatment 0.233 -0.0413 -0.43 0.186 -0.0516 -0.62 -0.7433 -0.9851 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 O24 mock treatment 0.265 -0.00931 -0.1 0.238 4.06E-4 0.0 -0.0657 -0.6711 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P01 compound treatment 0.357 0.0827 0.87 0.254 0.0164 0.2 0.7529 0.8456 3040805 ChemDiv3_015115 CN(c1ccccc1C(=O)O)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P02 compound treatment 0.281 0.00669 0.07 0.222 -0.0156 -0.19 -0.0823 -0.4126 1874619 ChemDiv3_015116 Cc1cc2NC(=O)CC(=Nc2cc1C)c3ccccc3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P03 compound treatment 0.312 0.0377 0.4 0.268 0.0304 0.36 0.5371 0.9991 3040809 ChemDiv3_015117 CNc1nc(ncc1F)N2CCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P04 compound treatment 0.179 -0.0953 -1.0 0.177 -0.0606 -0.72 -1.2205 -0.9874 3040810 ChemDiv3_015118 COc1ccccc1C2=NOC(COc3ccc(Cl)c4cccnc34)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P05 compound treatment 0.639 0.365 3.83 0.558 0.32 3.83 5.419 1.0 3040813 ChemDiv3_015119 CN1C(=O)CC(C1=O)c2cn(Cc3ccccc3)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P06 compound treatment 0.369 0.0947 0.99 0.338 0.1 1.2 1.5526 0.9956 3124173 ChemDiv3_015120 COc1ccc(cc1)c2cc(n3ncc(C(=O)Nc4cccc(O)c4)c3n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P07 compound treatment 0.303 0.0287 0.3 0.275 0.0374 0.45 0.5295 0.9815 3040816 ChemDiv3_015121 OC(=O)C(Cc1ccccc1)Nc2ncnc3c4ccccc4oc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P08 compound treatment 0.156 -0.118 -1.24 0.157 -0.0806 -0.96 -1.5605 -0.9921 3124174 ChemDiv3_015122 O=C(NCCCn1ccnc1)c2cc(on2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P09 compound treatment 0.247 -0.0273 -0.29 0.177 -0.0606 -0.72 -0.7155 -0.9177 3124175 ChemDiv3_015123 CCc1ccc(NC2=NC(=O)CC(N2)C(=O)Nc3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P10 compound treatment 0.194 -0.0803 -0.84 0.176 -0.0616 -0.74 -1.1175 -0.9977 3040822 ChemDiv3_015124 Cc1ccc(cc1)S(=O)(=O)CC2CSc3nnc(C)c(=O)n23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P11 compound treatment 0.875 0.601 6.31 0.751 0.513 6.14 8.8045 0.9999 3040861 ChemDiv3_015125 CCS(=O)(=O)c1nc2ccccc2n1Cc3ccc(cc3)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P12 compound treatment 0.045 -0.229 -2.41 0.047 -0.191 -2.28 -3.3154 -0.9996 3040862 ChemDiv3_015126 CC(C)CCC1C(=NN(C1=O)c2nc3ccccc3[nH]2)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P13 compound treatment 0.239 -0.0353 -0.37 0.228 -0.00959 -0.11 -0.3434 -0.8846 3040865 ChemDiv3_015127 Clc1ccc(CNC2CN3CCC2CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P14 compound treatment 0.221 -0.0533 -0.56 0.217 -0.0206 -0.25 -0.5702 -0.932 3040868 ChemDiv3_015128 CCc1c(C)nc([nH]c1=O)N2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P15 compound treatment 0.252 -0.0223 -0.23 0.217 -0.0206 -0.25 -0.3399 -0.9997 3040872 ChemDiv3_015129 CCn1c(NCCSc2nc3ccccc3n2C)nc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P16 compound treatment 0.114 -0.16 -1.68 0.105 -0.133 -1.59 -2.3123 -0.9996 3040874 ChemDiv3_015130 Cn1c(NCc2ccccc2)ncc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P17 compound treatment 0.07 -0.204 -2.15 0.076 -0.162 -1.93 -2.8844 -0.9986 3040877 ChemDiv3_015131 CCCn1c(Nc2nc3ccccc3n2C)nc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P18 compound treatment 0.23 -0.0443 -0.47 0.159 -0.0786 -0.94 -0.994 -0.9474 3040880 ChemDiv3_015132 Cc1n[nH]c(C)c1NC(=O)CSc2nc(C)cc(C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P19 compound treatment 0.214 -0.0603 -0.63 0.205 -0.0326 -0.39 -0.7237 -0.9728 3040932 ChemDiv3_015133 Cc1cn2c(nc3ccccc32)n1CCCO 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P20 compound treatment 1.381 1.11 11.62 1.372 1.13 13.57 17.8161 0.997 3040936 ChemDiv3_015134 CN(c1ccc(Cl)cc1)c2cc(=O)n(C)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P21 compound treatment 0.29 0.0157 0.16 0.263 0.0254 0.3 0.3314 0.9586 3040938 ChemDiv3_015135 CCOc1ccc(cc1S(=O)(=O)Nc2ccc(Cl)cn2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P22 compound treatment 0.14 -0.134 -1.41 0.128 -0.11 -1.31 -1.9247 -0.9993 3040941 ChemDiv3_015136 Cn1cc(NC(=O)NC2CCCCC2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P23 mock treatment 0.258 -0.0163 -0.17 0.203 -0.0346 -0.41 -0.4138 -0.9238 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2043 P24 mock treatment 0.256 -0.0183 -0.19 0.244 0.00641 0.08 -0.0818 -0.3951 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A01 compound treatment 0.197 -0.0331 -0.35 0.206 -0.0227 -0.27 -0.4382 -0.9925 3040942 ChemDiv3_015137 Cc1cccc(N2CCN(CC2)C(=O)Nc3cn(C)c(=O)c4ccccc34)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A02 compound treatment 0.207 -0.0231 -0.24 0.23 0.00128 0.02 -0.1609 -0.6612 3040946 ChemDiv3_015138 COc1cc2NC(=O)CC(c3ccccc3)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A03 compound treatment 0.204 -0.0261 -0.27 0.208 -0.0207 -0.25 -0.3693 -0.9987 3040947 ChemDiv3_015139 CC(=O)N(c1ccccc1)C2(CCCCC2)C(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A04 compound treatment 0.202 -0.0281 -0.3 0.262 0.0333 0.4 0.0727 0.1466 3040949 ChemDiv3_015140 CCc1nc2nc(C)cc(NCCc3ccccc3)n2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A05 compound treatment 0.229 -0.00112 -0.01 0.218 -0.0107 -0.13 -0.099 -0.769 3124176 ChemDiv3_015141 COc1ccc(cc1)C2C(C(=O)N3CCCC3)c4cc(OC)c(OC)cc4C(=O)N2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A06 compound treatment 1.019 0.789 8.29 0.954 0.725 8.68 11.9946 0.9997 3124177 ChemDiv3_015142 COc1cc(Cl)c(C)cc1NCC(O)Cn2nnnc2c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A07 compound treatment 0.195 -0.0351 -0.37 0.2 -0.0287 -0.34 -0.5038 -0.9994 3041005 ChemDiv3_015143 CC(=O)Nc1c(nc2ccccn12)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A08 compound treatment 0.225 -0.00512 -0.05 0.217 -0.0117 -0.14 -0.1372 -0.9136 3041006 ChemDiv3_015144 COc1ccc(NS(=O)(=O)c2c(C)nc3sccn3c2=O)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A09 compound treatment 0.067 -0.163 -1.71 0.07 -0.159 -1.9 -2.5542 -0.9987 3041010 ChemDiv3_015145 Cc1c(nnn1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A10 compound treatment 1.042 0.812 8.53 0.937 0.708 8.47 12.0216 1.0 3041011 ChemDiv3_015146 C(c1nnc(o1)c2ccccc2)c3ccc4OCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A11 compound treatment 0.162 -0.0681 -0.72 0.168 -0.0607 -0.73 -1.0196 -1.0 3041014 ChemDiv3_015147 CCc1ccc(NC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A12 compound treatment 0.748 0.518 5.44 0.664 0.435 5.21 7.5285 0.9998 3041016 ChemDiv3_015148 Clc1cccc(NC(=O)c2ncn(n2)c3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A13 compound treatment 0.375 0.145 1.52 0.439 0.21 2.52 2.8549 0.971 3041019 ChemDiv3_015149 CC(N1C(=O)COc2ccc(C)cc12)C(=O)NCc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A14 compound treatment 0.168 -0.0621 -0.65 0.172 -0.0567 -0.68 -0.9412 -0.9998 3041021 ChemDiv3_015150 Brc1cccc(c1)c2nnc(CN3CCOCC3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A15 compound treatment 0.147 -0.0831 -0.87 0.179 -0.0497 -0.59 -1.038 -0.9825 3124178 ChemDiv3_015151 CC1(CCC(=O)N1Cc2cccnc2)C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A16 compound treatment 0.236 0.00587 0.06 0.236 0.00728 0.09 0.1052 0.9857 3041025 ChemDiv3_015152 Cc1ccc(CN2CCN(CC(=O)N3CCC4(CC3)OCCO4)C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A17 compound treatment 0.209 -0.0211 -0.22 0.208 -0.0207 -0.25 -0.3322 -0.9985 3124179 ChemDiv3_015153 CC(C)CCN1C(C(=O)NCc2cccnc2)c3ccccc3C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A18 compound treatment 0.749 0.519 5.45 0.685 0.456 5.46 7.7136 1.0 3041087 ChemDiv3_015154 COc1ccc(cc1)N2Cc3cccc(C(=O)N4CCOCC4)c3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A19 compound treatment 0.184 -0.0461 -0.48 0.203 -0.0257 -0.31 -0.5601 -0.976 3041089 ChemDiv3_015155 CCN1CCN(CCNC(=O)Nc2ccccc2C)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A20 compound treatment 0.241 0.0109 0.11 0.259 0.0303 0.36 0.3369 0.887 3041093 ChemDiv3_015156 CCOC(=O)CCc1c(C)nn2cnnc2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A21 compound treatment 0.114 -0.116 -1.22 0.123 -0.106 -1.26 -1.7568 -0.9998 3041096 ChemDiv3_015157 COc1cc(NC(=O)NCC2CCN(Cc3cc(C)ccc3C)CC2)cc(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A22 compound treatment 0.322 0.0919 0.96 0.308 0.0793 0.95 1.353 1.0 3041099 ChemDiv3_015158 CCC(C)NC(=O)c1cccc2CN(CC3CCCO3)C(=O)c21 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A23 mock treatment 0.291 0.0609 0.64 0.259 0.0303 0.36 0.7083 0.9638 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 A24 mock treatment 0.275 0.0449 0.47 0.28 0.0513 0.61 0.7671 0.9915 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B01 compound treatment 0.308 0.0779 0.82 0.322 0.0933 1.12 1.3675 0.9883 3041100 ChemDiv3_015159 O=C(Nc1ccc2OCCOc2c1)c3cccc4CN(Cc5cccnc5)C(=O)c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B02 compound treatment 0.198 -0.0321 -0.34 0.195 -0.0337 -0.4 -0.5238 -0.9961 3124180 ChemDiv3_015160 O=C(Cn1ncc2ccsc2c1=O)NCCN3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B03 compound treatment 0.238 0.00787 0.08 0.232 0.00328 0.04 0.0862 0.942 3041104 ChemDiv3_015161 Cc1cc(C)cc(NS(=O)(=O)c2ccc3NC(=O)Cc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B04 compound treatment 0.487 0.257 2.7 0.463 0.234 2.8 3.8897 0.9998 3124181 ChemDiv3_015162 O=C(CCCn1nc(c2ccccc2)c3ccccc13)N4CCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B05 compound treatment 0.163 -0.0671 -0.7 0.167 -0.0617 -0.74 -1.0207 -0.9997 3124432 ChemDiv3_015163 CC(C)c1ccc(NC(=O)[C@H](N2Cc3ccccc3C2=O)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B06 compound treatment 0.32 0.0899 0.94 0.312 0.0833 1.0 1.372 0.9996 3041177 ChemDiv3_015164 CC(C)NC(=O)c1cccc2sc(nc12)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B07 compound treatment 0.428 0.198 2.08 0.419 0.19 2.28 3.0793 0.999 3041178 ChemDiv3_015165 COc1ccccc1CNC(=O)c2cc(C)c3c(C)nn(c4ccccc4Cl)c3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B08 compound treatment 0.931 0.701 7.36 0.903 0.674 8.07 10.9096 0.999 3041182 ChemDiv3_015166 O=C(Cn1ncc2COc3ccccc3-c21)N4CCCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B09 compound treatment 0.198 -0.0321 -0.34 0.186 -0.0427 -0.51 -0.6 -0.9797 3041185 ChemDiv3_015167 COc1ccc(CN2CC(CC2=O)C(=O)N3CCn4c(C3)nc5ccccc45)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B10 compound treatment 0.271 0.0409 0.43 0.269 0.0403 0.48 0.6443 0.9983 3041188 ChemDiv3_015168 COc1ccc(cc1)N2CCN(CC2)c3nc(no3)c4ccc(OC)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B11 compound treatment 0.183 -0.0471 -0.49 0.17 -0.0587 -0.7 -0.8467 -0.9853 3041190 ChemDiv3_015169 OC(=O)c1ncccc1C(=O)Nc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B12 compound treatment 0.201 -0.0291 -0.31 0.186 -0.0427 -0.51 -0.5777 -0.9699 3124295 ChemDiv3_015170 COc1ccc(cc1)N2CCN(CCCNC(=O)CN3C(=O)CCSc4ccccc34)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B13 compound treatment 0.382 0.152 1.6 0.305 0.0763 0.91 1.7733 0.9649 3041193 ChemDiv3_015171 Cc1cccc(c1)c2nnc(o2)C3CCNCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B14 compound treatment 0.185 -0.0451 -0.47 0.162 -0.0667 -0.8 -0.8996 -0.969 3124296 ChemDiv3_015172 CC1CCCC(C)N1CCCNC(=O)Cn2ncc3COc4ccc(C)cc4-c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B15 compound treatment 0.19 -0.0401 -0.42 0.183 -0.0457 -0.55 -0.6848 -0.9917 3040042 ChemDiv3_015173 O=C(Cn1nc(Cc2ccncc2)c3ccccc3c1=O)NCCCN4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B16 compound treatment 0.19 -0.0401 -0.42 0.158 -0.0707 -0.85 -0.8963 -0.9482 3040045 ChemDiv3_015174 CCN1CCN(CC1)c2c(cnc3ccccc23)C(=O)c4ccc(OC)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B17 compound treatment 0.298 0.0679 0.71 0.3 0.0713 0.85 1.1071 0.996 3040047 ChemDiv3_015175 CCOc1ccc(cc1)c2nc(SCC(=O)OC)c3Cc4cccc(OCC)c4Oc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B18 compound treatment 0.125 -0.105 -1.1 0.119 -0.11 -1.31 -1.7089 -0.9963 3040050 ChemDiv3_015176 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B19 compound treatment 0.548 0.318 3.34 0.521 0.292 3.5 4.8334 0.9997 3040053 ChemDiv3_015177 O=C(N1CCC2(CC1)OCCO2)c3ccc4SCCN(Cc5ccccc5)c4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B20 compound treatment 0.303 0.0729 0.77 0.31 0.0813 0.97 1.2289 0.993 3040055 ChemDiv3_015178 CN1C(=O)CSc2ccc(NC(=O)NCc3cccnc3)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B21 compound treatment 0.628 0.398 4.18 0.628 0.399 4.78 6.3328 0.9978 3124297 ChemDiv3_015179 CCN1CCSc2ccc(cc12)C(=O)NCc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B22 compound treatment 0.3 0.0699 0.73 0.254 0.0253 0.3 0.7328 0.9232 3040058 ChemDiv3_015180 Cc1ccccc1NC(=O)Cn2ncc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B23 mock treatment 0.225 -0.00512 -0.05 0.236 0.00728 0.09 0.0235 0.2299 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 B24 mock treatment 0.252 0.0219 0.23 0.266 0.0373 0.45 0.4779 0.9524 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C01 compound treatment 0.135 -0.0951 -1.0 0.145 -0.0837 -1.0 -1.4147 -1.0 3124298 ChemDiv3_015181 COC(=O)Cc1nc(no1)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C02 compound treatment 0.14 -0.0901 -0.95 0.152 -0.0767 -0.92 -1.3184 -0.9999 3124299 ChemDiv3_015182 Cc1cc2NC(=O)CC(c3ccncc3)c2cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C03 compound treatment 0.194 -0.0361 -0.38 0.211 -0.0177 -0.21 -0.4182 -0.9622 3040131 ChemDiv3_015183 O=C(Cc1c[nH]c2ccccc12)NC3(CCCCC3)C(=O)NC4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C04 compound treatment 0.168 -0.0621 -0.65 0.183 -0.0457 -0.55 -0.8482 -0.9962 3040134 ChemDiv3_015184 O=c1[nH]c2ccc(NS(=O)(=O)c3ccc(cc3)C4CCCCC4)cc2[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C05 compound treatment 0.465 0.235 2.47 0.409 0.18 2.16 3.2695 0.9978 3040136 ChemDiv3_015185 COc1ccc(cc1)C2C(CC(=O)N2c3ccc(OC)cc3)C(=O)Nc4ccc(C)c(F)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C06 compound treatment 0.691 0.461 4.84 0.577 0.348 4.17 6.3692 0.9972 3040138 ChemDiv3_015186 CCc1cccc(NCC(O)Cn2nnnc2c3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C07 compound treatment 1.323 1.09 11.48 1.351 1.12 13.43 17.6109 0.997 3040141 ChemDiv3_015187 Cc1ccc(Cn2c(=O)n(Cc3ccccc3)c(=O)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C08 compound treatment 0.223 -0.00712 -0.07 0.221 -0.00772 -0.09 -0.1182 -0.9946 3040143 ChemDiv3_015188 CC(C)CCNS(=O)(=O)c1c(C)nc2sccn2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C09 compound treatment 0.136 -0.0941 -0.99 0.129 -0.0997 -1.19 -1.5427 -0.9956 3040144 ChemDiv3_015189 OC(=O)c1ccc(cc1)N2CCCS2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C10 compound treatment 0.53 0.3 3.15 0.5 0.271 3.25 4.5221 0.9999 3124300 ChemDiv3_015190 O=C1CC(CN1c2ccccc2)c3nnc(o3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C11 compound treatment 0.891 0.661 6.94 0.898 0.669 8.01 10.5702 0.9975 3040149 ChemDiv3_015191 CCSc1nc2sc3CN(CCc3c2c(=O)n1c4ccccc4)C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C12 compound treatment 0.264 0.0339 0.36 0.241 0.0123 0.15 0.3555 0.9235 3124301 ChemDiv3_015192 OC1=NC2C=NN(C(=O)C2N=C1O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C13 compound treatment 0.25 0.0199 0.21 0.254 0.0253 0.3 0.3615 0.9836 3040214 ChemDiv3_015193 CC1Oc2ccc(C)cc2N(CCC(=O)N3CCC4(CC3)OCCO4)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C14 compound treatment 0.113 -0.117 -1.23 0.111 -0.118 -1.41 -1.8657 -0.9977 3040218 ChemDiv3_015194 CCCN(CCC)Cc1nnc(o1)c2cccc(Br)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C15 compound treatment 0.232 0.00188 0.02 0.18 -0.0487 -0.58 -0.3982 -0.6828 3040219 ChemDiv3_015195 CC1(CCC(=O)N1CCc2ccccc2)C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C16 compound treatment 0.203 -0.0271 -0.28 0.197 -0.0317 -0.38 -0.4698 -0.99 3040223 ChemDiv3_015196 CC1CN(CCN1c2cccc(C)c2)C(=O)CN3CCN(Cc4ccc(Cl)cc4)C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C17 compound treatment 0.208 -0.0221 -0.23 0.227 -0.00172 -0.02 -0.1789 -0.7667 3040225 ChemDiv3_015197 O=C(NCC1CCCO1)C2N(C3CCCCCC3)C(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C18 compound treatment 0.25 0.0199 0.21 0.236 0.00728 0.09 0.2092 0.9249 3040228 ChemDiv3_015198 O=c1[nH]c2ncccc2nc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C19 compound treatment 0.184 -0.0461 -0.48 0.17 -0.0587 -0.7 -0.8393 -0.9835 3040229 ChemDiv3_015199 Cc1ccccc1NC(=O)NCCCN2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C20 compound treatment 0.648 0.418 4.39 0.63 0.401 4.8 6.4982 0.999 3124302 ChemDiv3_015200 CCOC(=O)CCc1c(C)nn(c1C)c2ccc(Cl)nn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C21 compound treatment 0.319 0.0889 0.93 0.312 0.0833 1.0 1.3646 0.9995 3124303 ChemDiv3_015201 CC1CC(C)CN(C1)C(=O)C2C(N(C)C(=O)c3ccccc23)c4cn(C)c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C22 compound treatment 0.131 -0.0991 -1.04 0.129 -0.0997 -1.19 -1.5798 -0.9977 3040234 ChemDiv3_015202 Clc1cccc(NCc2cccc3CN(CC4CCCO4)Cc32)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C23 mock treatment 0.273 0.0429 0.45 0.231 0.00228 0.03 0.3377 0.7486 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 C24 mock treatment 0.275 0.0449 0.47 0.271 0.0423 0.51 0.691 0.9994 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D01 compound treatment 0.172 -0.0581 -0.61 0.176 -0.0527 -0.63 -0.8777 -0.9999 3040297 ChemDiv3_015203 CC(NC(=O)c1cccc2CN(Cc3cccnc3)C(=O)c21)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D02 compound treatment 0.14 -0.0901 -0.95 0.137 -0.0917 -1.1 -1.4453 -0.9973 3040299 ChemDiv3_015204 Cc1oc(nc1CS(=O)(=O)CC(=O)NCCN2CCOCC2)c3ccccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D03 compound treatment 0.261 0.0309 0.32 0.278 0.0493 0.59 0.6462 0.9603 3040301 ChemDiv3_015205 Cc1cc(NS(=O)(=O)c2ccc3NC(=O)Cc3c2)ccc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D04 compound treatment 0.865 0.635 6.67 0.838 0.609 7.29 9.8695 0.999 3040303 ChemDiv3_015206 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCCn3nc(c4ccccc4)c5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D05 compound treatment 0.201 -0.0291 -0.31 0.21 -0.0187 -0.22 -0.3747 -0.9883 3040305 ChemDiv3_015207 CCn1c(C)c(CCC(=O)Nc2ccc(cc2)C(=O)OC)c(=O)n3nc(cc13)c4ccccc4OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D06 compound treatment 0.476 0.246 2.58 0.512 0.283 3.39 4.2226 0.991 3124304 ChemDiv3_015208 CC(=O)N1CCc2c(C1)sc3n(Cc4cccc(C)c4)c(=O)n(Cc5ccccc5)c(=O)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D07 compound treatment 0.538 0.308 3.23 0.462 0.233 2.79 4.26 0.9973 3040306 ChemDiv3_015209 Cc1nn(c2ccccc2Cl)c3nc(cc(C)c13)C(=O)NCc4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D08 compound treatment 0.227 -0.00312 -0.03 0.211 -0.0177 -0.21 -0.1731 -0.807 3124305 ChemDiv3_015210 O=C(Cn1ncc2COc3ccccc3-c21)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D09 compound treatment 0.075 -0.155 -1.63 0.076 -0.153 -1.83 -2.4441 -0.9984 3040309 ChemDiv3_015211 CN(CC(O)c1ccc2N(CCc2c1)C(=O)C)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D10 compound treatment 0.468 0.238 2.5 0.428 0.199 2.38 3.4525 0.9997 3124306 ChemDiv3_015212 CCOc1ccc(cc1)N(CC)c2nc(no2)c3ccc(OC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D11 compound treatment 0.455 0.225 2.36 0.387 0.158 1.89 3.0091 0.994 3124307 ChemDiv3_015213 CCOC(=O)c1c(nn2CN(CCc3ccccc3)CNc12)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D12 compound treatment 0.289 0.0589 0.62 0.238 0.00928 0.11 0.5158 0.821 3040311 ChemDiv3_015214 O=C(CN1C(=O)CCSc2ccccc12)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D13 compound treatment 0.998 0.768 8.06 0.892 0.663 7.94 11.3141 1.0 3124308 ChemDiv3_015215 Cc1cccc(c1)c2nnc(o2)C3CCN(CC3)S(=O)(=O)Cc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D14 compound treatment 0.401 0.171 1.79 0.518 0.289 3.46 3.7164 0.9532 3040313 ChemDiv3_015216 c1sc2nc3ccccc3n2c1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D15 compound treatment 0.151 -0.0791 -0.83 0.138 -0.0907 -1.09 -1.3551 -0.9913 3124309 ChemDiv3_015217 Cn1nc(C(=O)NCCN2CCC(Cc3ccccc3)CC2)c4COc5ccccc5-c41 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D16 compound treatment 0.469 0.239 2.51 0.422 0.193 2.31 3.4092 0.9992 3040315 ChemDiv3_015218 COc1ccc2ncc(c(N3CCCCC3C)c2c1)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D17 compound treatment 0.166 -0.0641 -0.67 0.179 -0.0497 -0.59 -0.8969 -0.9981 3124310 ChemDiv3_015219 CN(C)CCNC(=O)c1ccc(C)c(NC2=NC3CS(=O)(=O)CC3S2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D18 compound treatment 0.157 -0.0731 -0.77 0.132 -0.0967 -1.16 -1.3613 -0.9802 3040318 ChemDiv3_015220 CCNC(=O)C1CCN(CC1)c2nc3c(C)cc(C)cc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D19 compound treatment 0.432 0.202 2.12 0.376 0.147 1.76 2.7452 0.9958 3124311 ChemDiv3_015221 Fc1ccc(CN2CCSc3ccc(cc23)C(=O)N4CCCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D20 compound treatment 0.198 -0.0321 -0.34 0.225 -0.00372 -0.04 -0.27 -0.7935 3040338 ChemDiv3_015222 CCc1nnc(NC(=O)Nc2ccc3SCC(=O)N(C)c3c2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D21 compound treatment 0.234 0.00388 0.04 0.22 -0.00872 -0.1 -0.045 -0.4017 3041514 ChemDiv3_015223 CCN1CCSc2ccc(cc12)C(=O)NC(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D22 compound treatment 0.427 0.197 2.07 0.322 0.0933 1.12 2.2513 0.9581 3041515 ChemDiv3_015224 CC(NC(=O)Cn1ncc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D23 mock treatment 0.276 0.0459 0.48 0.247 0.0183 0.22 0.4954 0.9362 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 D24 mock treatment 0.268 0.0379 0.4 0.245 0.0163 0.19 0.419 0.946 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E01 compound treatment 0.148 -0.0821 -0.86 0.15 -0.0787 -0.94 -1.2759 -0.999 3041516 ChemDiv3_015225 Clc1ccc(OCC(=O)Nc2ccc(cc2)c3nnc4CCCCCn34)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E02 compound treatment 0.195 -0.0351 -0.37 0.225 -0.00372 -0.04 -0.2923 -0.7867 3041517 ChemDiv3_015226 COCCN1C(C(C(=O)N2CCCC2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E03 compound treatment 0.174 -0.0561 -0.59 0.162 -0.0667 -0.8 -0.9813 -0.9889 3041518 ChemDiv3_015227 COCCN1C(C(C(=O)NCCN(C)C)c2ccccc2C1=O)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E04 compound treatment 0.237 0.00687 0.07 0.218 -0.0107 -0.13 -0.0396 -0.2692 3041519 ChemDiv3_015228 O=C(NCCc1ccccc1)c2nnc(CS(=O)(=O)c3ccccc3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E05 compound treatment 0.189 -0.0411 -0.43 0.198 -0.0307 -0.37 -0.5653 -0.9968 3124312 ChemDiv3_015229 COc1ccc(cc1)N2C(C(CC2=O)C(=O)NC3CCCCC3)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E06 compound treatment 0.215 -0.0151 -0.16 0.237 0.00828 0.1 -0.0423 -0.2258 3041520 ChemDiv3_015230 COc1cccc(CNCC(O)Cn2nnnc2c3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E07 compound treatment 0.157 -0.0731 -0.77 0.146 -0.0827 -0.99 -1.2429 -0.9921 3124313 ChemDiv3_015231 Cn1ncc2c(=O)n(CC(=O)c3ccccc3)cnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E08 compound treatment 0.177 -0.0531 -0.56 0.169 -0.0597 -0.71 -0.8998 -0.9925 3041521 ChemDiv3_015232 COc1ccc(Cc2nnn[nH]2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E09 compound treatment 0.29 0.0599 0.63 0.193 -0.0357 -0.43 0.1425 0.1874 3124314 ChemDiv3_015233 COC(=O)c1cnn2c(=O)cc(C)[nH]c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E10 compound treatment 0.363 0.133 1.4 0.321 0.0923 1.1 1.7675 0.9933 3124315 ChemDiv3_015234 Fc1ccc(Cc2nnc(o2)C(=O)N3CCCC3)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E11 compound treatment 0.201 -0.0291 -0.31 0.192 -0.0367 -0.44 -0.5269 -0.9843 3041522 ChemDiv3_015235 COc1ccc(Cn2cc[nH]c(=O)c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E12 compound treatment 0.21 -0.0201 -0.21 0.208 -0.0207 -0.25 -0.3247 -0.9969 3124316 ChemDiv3_015236 CNc1c(NC(=O)C2CN(C(=O)C2)c3ccccc3)c(=O)oc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E13 compound treatment 0.107 -0.123 -1.29 0.112 -0.117 -1.4 -1.9018 -0.9993 3041523 ChemDiv3_015237 CCn1cnc2cc(NCc3ccccc3OC)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E14 compound treatment 0.946 0.716 7.52 0.838 0.609 7.29 10.4711 0.9999 3124317 ChemDiv3_015238 CN(Cc1nnc(o1)c2cccc(Br)c2)c3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E15 compound treatment 0.289 0.0589 0.62 0.223 -0.00572 -0.07 0.3889 0.625 3041524 ChemDiv3_015239 COc1ccc(CCNC(=O)C2(C)CCC(=O)N2CCC(C)C)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E16 compound treatment 0.185 -0.0451 -0.47 0.231 0.00228 0.03 -0.3158 -0.6653 3124318 ChemDiv3_015240 O=C(CN1CCN(Cc2ccccc2)C1=O)NCCCN3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E17 compound treatment 0.361 0.131 1.37 0.277 0.0483 0.58 1.3804 0.9258 3124319 ChemDiv3_015241 CCc1ccc(CN2C(C(=O)NCC3CCCO3)c4ccccc4C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E18 compound treatment 0.079 -0.151 -1.59 0.073 -0.156 -1.86 -2.4397 -0.9968 3041525 ChemDiv3_015242 Clc1nc2ncccc2nc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E19 compound treatment 0.316 0.0859 0.9 0.263 0.0343 0.41 0.9278 0.9364 3124320 ChemDiv3_015243 CCc1ccc(NC(=O)NCCCN2CCN(CC2)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E20 compound treatment 0.336 0.106 1.11 0.351 0.122 1.46 1.8208 0.9908 3041526 ChemDiv3_015244 CCOC(=O)CCc1c(C)nn(c1C)c2ccc(nn2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E21 compound treatment 0.239 0.00887 0.09 0.225 -0.00372 -0.04 0.0344 0.3335 3124321 ChemDiv3_015245 CN1C(C(C(=O)NC2CC2)c3ccccc3C1=O)c4cn(C)c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E22 compound treatment 0.321 0.0909 0.95 0.261 0.0323 0.39 0.948 0.9207 3041527 ChemDiv3_015246 Cc1ccc(NCc2cccc3CN(CC4CCCO4)Cc32)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E23 mock treatment 0.229 -0.00112 -0.01 0.228 -7.19E-4 -0.01 -0.0144 -0.9878 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 E24 mock treatment 0.252 0.0219 0.23 0.245 0.0163 0.19 0.3002 0.9966 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F01 compound treatment 0.205 -0.0251 -0.26 0.217 -0.0117 -0.14 -0.2857 -0.9562 3124322 ChemDiv3_015247 COCCN1Cc2cccc(C(=O)NCc3ccccn3)c2C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F02 compound treatment 1.187 0.957 10.05 1.211 0.982 11.75 15.4165 0.997 3124323 ChemDiv3_015248 COc1ccc(CCNC(=O)c2cc3sc(C)cc3n2C)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F03 compound treatment 0.249 0.0189 0.2 0.229 2.81E-4 0.0 0.1426 0.719 3041528 ChemDiv3_015249 CCc1cccc(NS(=O)(=O)c2ccc3NC(=O)Cc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F04 compound treatment 1.196 0.966 10.14 1.104 0.875 10.47 14.5781 0.9999 3124433 ChemDiv3_015250 O=C(CCCn1nc(c2ccccc2)c3ccccc13)NCc4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F05 compound treatment 1.089 0.859 9.02 1.072 0.843 10.09 13.5127 0.9984 3041529 ChemDiv3_015251 CCCNC(=O)c1cc(C)c2c(C)nn(c3ccccc3)c2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F06 compound treatment 0.257 0.0269 0.28 0.232 0.00328 0.04 0.2273 0.7978 3124434 ChemDiv3_015252 CCn1c(=O)n(c2ccccc2)c(=O)c3c4CCN(Cc4sc13)C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F07 compound treatment 0.111 -0.119 -1.25 0.111 -0.118 -1.41 -1.8806 -0.9983 3124435 ChemDiv3_015253 Cc1nn(c2ccccc2Cl)c3nc(cc(C)c13)C(=O)NCC4CCN(C4)C5CCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F08 compound treatment 0.234 0.00388 0.04 0.261 0.0323 0.39 0.3019 0.7773 3041530 ChemDiv3_015254 CN(C(=O)Cn1ncc2COc3ccccc3-c21)c4cccc(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F09 compound treatment 0.225 -0.00512 -0.05 0.208 -0.0207 -0.25 -0.2133 -0.841 3124436 ChemDiv3_015255 O=C(CCc1c[nH]c2ccccc12)N3CCn4c(C3)nc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F10 compound treatment 0.984 0.754 7.92 0.955 0.726 8.69 11.7431 0.9989 3041531 ChemDiv3_015256 COc1ccc(CNc2nc(no2)c3ccc(OC)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F11 compound treatment 0.117 -0.113 -1.19 0.128 -0.101 -1.21 -1.6922 -1.0 3124437 ChemDiv3_015257 COc1cccc(NC(=O)c2ccnc(c2)N3CCC(CC3)C(=O)O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F12 compound treatment 0.257 0.0269 0.28 0.249 0.0203 0.24 0.3712 0.9972 3041532 ChemDiv3_015258 CC1CN(CCN1c2cccc(C)c2)C(=O)CN3C(=O)CCSc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F13 compound treatment 0.247 0.0169 0.18 0.177 -0.0517 -0.62 -0.3122 -0.4851 3124438 ChemDiv3_015259 O=C(CCc1nc2cccnc2n1c3ccccc3)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F14 compound treatment 0.089 -0.141 -1.48 0.092 -0.137 -1.64 -2.2047 -0.9988 3124439 ChemDiv3_015260 CCc1ccc2ncc(C(=O)c3ccccc3)c(N4CCOCC4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F15 compound treatment 0.275 0.0449 0.47 0.265 0.0363 0.43 0.6402 0.9992 3041533 ChemDiv3_015261 CCC(C)NC(=O)C1CCCN(C1)c2nc(no2)c3ccc(OC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F16 compound treatment 0.56 0.33 3.46 0.574 0.345 4.13 5.3709 0.9962 3124440 ChemDiv3_015262 CCOc1ccc(Nc2c(cnc3ccc(OCC)cc23)S(=O)(=O)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F17 compound treatment 0.247 0.0169 0.18 0.226 -0.00272 -0.03 0.1023 0.5678 3124441 ChemDiv3_015263 COc1cccc(Nc2nnc(Cc3cccnc3)c4ccccc24)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F18 compound treatment 0.253 0.0229 0.24 0.169 -0.0597 -0.71 -0.3353 -0.4449 3041534 ChemDiv3_015264 CCCNC(=O)Cn1nc(C)n2c(cc3cc(C)ccc32)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F19 compound treatment 1.021 0.791 8.31 0.948 0.719 8.61 11.9587 0.9998 3124442 ChemDiv3_015265 COc1cccc(NC(=O)c2ccc3SCCN(C)c3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F20 compound treatment 0.288 0.0579 0.61 0.248 0.0193 0.23 0.5929 0.912 3041535 ChemDiv3_015266 CN1CC(=O)N=C1NC(=O)Nc2ccc3SCC(=O)N(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F21 compound treatment 0.398 0.168 1.76 0.371 0.142 1.7 2.4504 0.9998 3124443 ChemDiv3_015267 CCCNC(=O)c1ccc2SCCN(CC)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F22 compound treatment 0.261 0.0309 0.32 0.226 -0.00272 -0.03 0.2063 0.633 3124444 ChemDiv3_015268 CC1CCc2nc3sc(NC(=O)Nc4ccccc4C)c(C)c3c(=O)n2CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F23 mock treatment 0.21 -0.0201 -0.21 0.255 0.0263 0.31 0.0729 0.1924 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 F24 mock treatment 0.229 -0.00112 -0.01 0.232 0.00328 0.04 0.0194 0.4733 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G01 compound treatment 0.361 0.131 1.37 0.319 0.0903 1.08 1.7357 0.9929 1720454 ChemDiv3_015269 CCOc1ccc(cc1)C(=O)N2CC(=O)Nc3ccc(C)cc3C2c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G02 compound treatment 0.217 -0.0131 -0.14 0.23 0.00128 0.02 -0.0866 -0.6246 3124445 ChemDiv3_015270 COCCN1C(C(C(=O)NC2CCCC2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G03 compound treatment 0.194 -0.0361 -0.38 0.212 -0.0167 -0.2 -0.4097 -0.9553 3124446 ChemDiv3_015271 CCCCN(CC)C(=O)C1C(N(CCOC)C(=O)c2ccccc12)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G04 compound treatment 0.227 -0.00312 -0.03 0.242 0.0133 0.16 0.0892 0.5495 3041536 ChemDiv3_015272 COc1cccc(CNC(=O)c2nnc(CS(=O)(=O)c3ccccc3)o2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G05 compound treatment 0.132 -0.0981 -1.03 0.136 -0.0927 -1.11 -1.5131 -0.9993 1483093 ChemDiv3_015273 Cn1c(CNc2ccc(F)cc2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G06 compound treatment 0.268 0.0379 0.4 0.28 0.0513 0.61 0.7151 0.978 3124447 ChemDiv3_015274 Cc1cc(Nc2ccc(cc2)C(=O)Nc3ccc4OCOc4c3)n5ncnc5n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G07 compound treatment 0.087 -0.143 -1.5 0.091 -0.138 -1.65 -2.228 -0.9989 3124448 ChemDiv3_015275 Cc1ccc(Cl)cc1NC(=O)Cn2cnc3n(C)ncc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G08 compound treatment 0.194 -0.0361 -0.38 0.182 -0.0467 -0.56 -0.6635 -0.9822 3041537 ChemDiv3_015276 COc1cccc(CNS(=O)(=O)c2c(C)nc3sccn3c2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G09 compound treatment 0.203 -0.0271 -0.28 0.187 -0.0417 -0.5 -0.5544 -0.9646 3124449 ChemDiv3_015277 COC(=O)c1cnn2c(=O)c3CCCc3[nH]c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G10 compound treatment 0.351 0.121 1.27 0.341 0.112 1.34 1.8476 0.9996 3041538 ChemDiv3_015278 CCN1CCN(CC1)C(=O)c2cccc(Nc3nc4ccccc4n5nnnc35)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G11 compound treatment 0.17 -0.0601 -0.63 0.177 -0.0517 -0.62 -0.8841 -0.9999 3124450 ChemDiv3_015279 Cc1noc(CCn2c(=O)[nH]c3ccccc3c2=O)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G12 compound treatment 0.118 -0.112 -1.18 0.127 -0.102 -1.22 -1.6933 -0.9999 3124451 ChemDiv3_015280 CC1CCN(CC1)c2ccc(NS(=O)(=O)c3c(C)nc4sccn4c3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G13 compound treatment 0.205 -0.0251 -0.26 0.207 -0.0217 -0.26 -0.3703 -1.0 3041539 ChemDiv3_015281 Cn1cnc2cc(NCc3ccccn3)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G14 compound treatment 0.684 0.454 4.77 0.585 0.356 4.26 6.3849 0.9984 3124452 ChemDiv3_015282 COc1cccc(CNC(=O)c2ccc(Nc3nc4ccccc4n5nnnc35)cc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G15 compound treatment 0.426 0.196 2.06 0.343 0.114 1.37 2.4215 0.9803 3041540 ChemDiv3_015283 CC1CCCC(NC(=O)C2N(CCc3ccccc3)C(=O)c4ccccc24)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G16 compound treatment 0.285 0.0549 0.58 0.273 0.0443 0.53 0.7822 0.9991 3124453 ChemDiv3_015284 COc1ccc(cc1)N2CCN(CCCNS(=O)(=O)c3c(C)noc3C)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G17 compound treatment 0.24 0.00987 0.1 0.247 0.0183 0.22 0.228 0.9419 3124454 ChemDiv3_015285 COc1ccc(CN2C(C(=O)NCCCN3CC(C)CC(C)C3)c4ccccc4C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G18 compound treatment 0.625 0.395 4.15 0.563 0.334 4.0 5.7606 0.9998 3041541 ChemDiv3_015286 Cc1nn(c2ccc(C)c(C)c2)c3nc(cc(C)c13)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G19 compound treatment 0.166 -0.0641 -0.67 0.178 -0.0507 -0.61 -0.9053 -0.9986 3124455 ChemDiv3_015287 Clc1ccc(NC(=O)NCC2CCN(Cc3cccc(Cl)c3)CC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G20 compound treatment 0.208 -0.0221 -0.23 0.227 -0.00172 -0.02 -0.1789 -0.7667 3041542 ChemDiv3_015288 CCOC(=O)CCc1c(C)nn(c1C)c2ccc3nnc(C)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G21 compound treatment 0.219 -0.0111 -0.12 0.24 0.0113 0.13 0.0128 0.0718 3124456 ChemDiv3_015289 CCc1cccc(NC(=O)C2C(N(C)C(=O)c3ccccc23)c4cn(C)c5ccccc45)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G22 compound treatment 0.182 -0.0481 -0.51 0.181 -0.0477 -0.57 -0.7611 -0.9982 3041543 ChemDiv3_015290 COc1cccc(NCc2cccc3CN(CC4CCCO4)Cc32)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G23 mock treatment 0.2 -0.0301 -0.32 0.22 -0.00872 -0.1 -0.2975 -0.893 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 G24 mock treatment 0.22 -0.0101 -0.11 0.238 0.00928 0.11 0.0033 0.0216 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H01 compound treatment 0.146 -0.0841 -0.88 0.157 -0.0717 -0.86 -1.2315 -0.9999 3124457 ChemDiv3_015291 COCCN1Cc2cccc(C(=O)N3CCN(CC3)C4CCCCC4)c2C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H02 compound treatment 0.322 0.0919 0.96 0.274 0.0453 0.54 1.0654 0.9627 3124458 ChemDiv3_015292 CCc1cc2n(C)c(cc2s1)C(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H03 compound treatment 0.193 -0.0371 -0.39 0.205 -0.0237 -0.28 -0.4764 -0.9878 3041544 ChemDiv3_015293 CCOC(=O)C1CCCN(C1)C(=O)c2ccc(CS(=O)c3ccccc3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H04 compound treatment 1.349 1.12 11.75 1.275 1.05 12.52 17.161 0.9995 3124701 ChemDiv3_015294 CCCCN(C1CCN(CC1)C(=O)C)C(=O)c2cc3COc4ccccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H05 compound treatment 1.425 1.19 12.55 1.381 1.15 13.79 18.6222 0.9989 3041545 ChemDiv3_015295 CC1CCN(CC1)C(=O)c2cc(C)c3c(C)nn(c4ccccc4)c3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H06 compound treatment 1.33 1.1 11.55 1.331 1.1 13.19 17.4937 0.9978 3124568 ChemDiv3_015296 COc1cccc(Cn2c(=O)n(Cc3ccccc3)c(=O)c4cccnc24)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H07 compound treatment 0.165 -0.0651 -0.68 0.159 -0.0697 -0.83 -1.0735 -0.9951 3124569 ChemDiv3_015297 CC1CCN(CC1)C(=O)CCc2c(C)nc3n(C)c(=O)n(C)c(=O)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H08 compound treatment 0.168 -0.0621 -0.65 0.174 -0.0547 -0.65 -0.9243 -1.0 3041546 ChemDiv3_015298 O=C(Cn1ncc2COc3ccccc3-c21)Nc4nccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H09 compound treatment 0.189 -0.0411 -0.43 0.198 -0.0307 -0.37 -0.5653 -0.9968 3124570 ChemDiv3_015299 CN(C)CC(O)c1ccc2cc[nH]c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H10 compound treatment 1.088 0.858 9.01 1.064 0.835 9.99 13.4376 0.9987 3041547 ChemDiv3_015300 COc1ccc(cc1)c2noc(n2)N(C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H11 compound treatment 0.355 0.125 1.31 0.293 0.0643 0.77 1.4712 0.9677 3041694 ChemDiv3_015301 CCS(=O)(=O)N1CCC(=CC1)c2c(C)n(CC(=O)N3CCCC3)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H12 compound treatment 0.179 -0.0511 -0.54 0.193 -0.0357 -0.43 -0.6819 -0.9936 3041695 ChemDiv3_015302 CCOc1ccc(NC(=O)CC2Oc3ccccc3NC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H13 compound treatment 0.281 0.0509 0.53 0.275 0.0463 0.55 0.7694 0.9998 3041696 ChemDiv3_015303 CC(C)NC(=O)CCc1nc2cccnc2n1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H14 compound treatment 0.273 0.0429 0.45 0.244 0.0153 0.18 0.4477 0.9212 3041697 ChemDiv3_015304 CCOC(=O)C1CCN(CC1)c2c(cnc3ccc(CC)cc23)C(=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H15 compound treatment 0.145 -0.0851 -0.89 0.166 -0.0627 -0.75 -1.1628 -0.9962 3041699 ChemDiv3_015305 C1CCN(C1)c2ncnc3n4CCCCCc4nc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H16 compound treatment 0.385 0.155 1.63 0.373 0.144 1.73 2.3708 0.9996 3041700 ChemDiv3_015306 CCOc1ccc(CCNC(=O)C(C)N2C(=O)CC(C)(C)Sc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H17 compound treatment 0.234 0.00388 0.04 0.228 -7.19E-4 -0.01 0.0227 0.5456 3124571 ChemDiv3_015307 O=C(Cn1nc(Cc2ccncc2)c3ccccc3c1=O)N4CCCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H18 compound treatment 0.3 0.0699 0.73 0.284 0.0553 0.66 0.9866 0.9987 3041701 ChemDiv3_015308 CCC(C)NC(=O)CSc1cc(C)nc2c(c(C)nn12)c3ccccc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H19 compound treatment 0.122 -0.108 -1.14 0.122 -0.107 -1.28 -1.7058 -0.9983 3041759 ChemDiv3_015309 CCNC(=O)c1ccc2SCCN(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H20 compound treatment 0.247 0.0169 0.18 0.217 -0.0117 -0.14 0.0262 0.1158 3041760 ChemDiv3_015310 CN1C(=O)CSc2ccc(NC(=O)N3CCOCC3)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H21 compound treatment 0.12 -0.11 -1.16 0.126 -0.103 -1.23 -1.6869 -0.9995 3041762 ChemDiv3_015311 CCN1CCSc2ccc(cc12)C(=O)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H22 compound treatment 0.303 0.0729 0.77 0.263 0.0343 0.41 0.8312 0.9572 3041763 ChemDiv3_015312 Cc1ccc(CN2C(=O)CSc3ccc(NC(=O)NCc4ccccc4)cc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H23 mock treatment 0.243 0.0129 0.14 0.195 -0.0337 -0.4 -0.1896 -0.4457 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 H24 mock treatment 0.241 0.0109 0.11 0.229 2.81E-4 0.0 0.0831 0.7276 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I01 compound treatment 1.145 0.915 9.61 1.075 0.846 10.13 13.954 0.9997 1630475 ChemDiv3_015313 Brc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)CC4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I02 compound treatment 0.167 -0.0631 -0.66 0.176 -0.0527 -0.63 -0.9148 -0.9997 3041765 ChemDiv3_015314 NC(=O)c1nnc(Cc2ccc(Cl)cc2Cl)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I03 compound treatment 0.22 -0.0101 -0.11 0.246 0.0173 0.21 0.071 0.3054 3124572 ChemDiv3_015315 COc1ccc(cc1)C2C(C(=O)Nc3cnc4ccccc4c3)c5ccccc5C(=O)N2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I04 compound treatment 0.145 -0.0851 -0.89 0.164 -0.0647 -0.77 -1.1797 -0.9974 3041767 ChemDiv3_015316 OC(CNCCc1ccccc1)Cn2nnnc2c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I05 compound treatment 0.231 8.75E-4 0.01 0.254 0.0253 0.3 0.2204 0.7283 3124573 ChemDiv3_015317 CC1CC(C)CN(C1)C(=O)C2C(N(C)C(=O)c3ccccc23)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I06 compound treatment 0.205 -0.0251 -0.26 0.206 -0.0227 -0.27 -0.3788 -0.9999 3041769 ChemDiv3_015318 OC(CN1CCN(CC1)c2cccnc2)Cn3nnnc3c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I07 compound treatment 0.615 0.385 4.04 0.634 0.405 4.85 6.287 0.9959 3124574 ChemDiv3_015319 Cc1ccc(Cn2cnc3n(C)ncc3c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I08 compound treatment 0.268 0.0379 0.4 0.258 0.0293 0.35 0.529 0.998 3041770 ChemDiv3_015320 Cc1nc2sccn2c(=O)c1S(=O)(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I09 compound treatment 0.316 0.0859 0.9 0.299 0.0703 0.84 1.2323 0.9994 3124575 ChemDiv3_015321 CC(C)CCn1c(=O)c2sccc2n3c(CCCC(=O)O)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I10 compound treatment 0.273 0.0429 0.45 0.288 0.0593 0.71 0.8199 0.976 3041772 ChemDiv3_015322 CCc1nn2c(=O)c(c(C)nc2s1)S(=O)(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I11 compound treatment 0.138 -0.0921 -0.97 0.153 -0.0757 -0.91 -1.3248 -0.9995 3124576 ChemDiv3_015323 Oc1ccccc1C2=NC(NC(C2)c3cccnc3)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I12 compound treatment 0.098 -0.132 -1.39 0.114 -0.115 -1.37 -1.9518 -1.0 3124577 ChemDiv3_015324 CN1c2ccccc2Oc3nnc(NCc4ccccc4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I13 compound treatment 0.102 -0.128 -1.35 0.109 -0.12 -1.43 -1.9644 -0.9995 3041775 ChemDiv3_015325 CCn1cnc2cc(NCc3ccccn3)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I14 compound treatment 0.152 -0.0781 -0.82 0.157 -0.0717 -0.86 -1.1869 -0.9997 3124578 ChemDiv3_015326 COc1ccc(CCNc2cc3N(C)c4ccccc4Oc3nn2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I15 compound treatment 0.362 0.132 1.39 0.338 0.109 1.31 1.9039 0.9996 3124579 ChemDiv3_015327 CC(CCc1ccccc1)N2C(C(=O)NCCc3ccccc3)c4ccccc4C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I16 compound treatment 0.435 0.205 2.15 0.451 0.222 2.66 3.402 0.9945 3041777 ChemDiv3_015328 CCc1nc2n(ncc2c(=O)n1c3ccc(OC)c(Cl)c3)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I17 compound treatment 0.262 0.0319 0.33 0.219 -0.00972 -0.12 0.1545 0.436 3041779 ChemDiv3_015329 Clc1ccc2[nH]c(=O)n(Cc3ccccc3)c(=O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I18 compound treatment 0.45 0.22 2.31 0.435 0.206 2.47 3.3781 0.9994 3124580 ChemDiv3_015330 CCc1ccc(NCc2c(cnn2c3ccccc3)C(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I19 compound treatment 0.213 -0.0171 -0.18 0.222 -0.00672 -0.08 -0.184 -0.9341 3124581 ChemDiv3_015331 CCc1ccc(NC(=O)NCCCN2CCCc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I20 compound treatment 0.27 0.0399 0.42 0.235 0.00628 0.08 0.3493 0.8209 3041781 ChemDiv3_015332 Cc1nn(c(C)c1CCC(=O)O)c2ccc3nnc(C)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I21 compound treatment 0.178 -0.0521 -0.55 0.195 -0.0337 -0.4 -0.6724 -0.9887 1362464 ChemDiv3_015333 Cc1ccn2c(NC3CCCC3)c(nc2c1)c4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I22 compound treatment 0.253 0.0229 0.24 0.204 -0.0247 -0.3 -0.0392 -0.103 3041783 ChemDiv3_015334 COC(=O)c1cc(NC(=O)c2cccc3CN(Cc4cccnc4)C(=O)c32)cc(c1)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I23 mock treatment 0.209 -0.0211 -0.22 0.194 -0.0347 -0.42 -0.4506 -0.9569 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 I24 mock treatment 0.229 -0.00112 -0.01 0.226 -0.00272 -0.03 -0.0314 -0.906 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J01 compound treatment 0.201 -0.0291 -0.31 0.211 -0.0177 -0.21 -0.3662 -0.984 3041876 ChemDiv3_015335 COCCN1Cc2cccc(C(=O)N3CCN(CC3)c4ccc(F)cc4)c2C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J02 compound treatment 0.355 0.125 1.31 0.456 0.227 2.72 2.8502 0.9441 3041817 ChemDiv3_015336 Fc1ccc(NC(=O)CCCn2nc(c3ccccc3)c4cc(Cl)ccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J03 compound treatment 0.291 0.0609 0.64 0.284 0.0553 0.66 0.9198 0.9999 3041819 ChemDiv3_015337 Clc1ccc(CCNC(=O)c2ccc(CS(=O)c3ccc(Cl)cc3)o2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J04 compound treatment 0.82 0.59 6.2 0.656 0.427 5.11 7.9956 0.9954 3041820 ChemDiv3_015338 CCOC(=O)c1c(NC(=O)CN2C(=O)CCSc3ccccc23)sc4CCCCc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J05 compound treatment 0.337 0.107 1.12 0.321 0.0923 1.1 1.5744 1.0 3041821 ChemDiv3_015339 O=C(NCc1ccccc1)c2cnc(nc2)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J06 compound treatment 1.422 1.19 12.52 1.396 1.17 13.97 18.7268 0.9985 3041822 ChemDiv3_015340 Clc1ccc(Cn2c(=O)n(C3CCCCC3)c(=O)c4cccnc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J07 compound treatment 0.304 0.0739 0.78 0.335 0.106 1.27 1.4478 0.9719 3041824 ChemDiv3_015341 COc1ccc(cc1)c2cc3c(cc(NC(=O)c4ccco4)cc3n2C)S(=O)(=O)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J08 compound treatment 0.186 -0.0441 -0.46 0.177 -0.0517 -0.62 -0.7652 -0.9899 3124582 ChemDiv3_015342 CC1CCCCN1CCNC(=O)Cn2ncc3COc4ccccc4-c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J09 compound treatment 0.173 -0.0571 -0.6 0.199 -0.0297 -0.36 -0.6757 -0.9688 3041826 ChemDiv3_015343 CCc1ccc(cc1)N2Cc3ccncc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J10 compound treatment 1.34 1.11 11.66 1.364 1.14 13.58 17.8471 0.9971 3124583 ChemDiv3_015344 COc1ccc(cc1)c2noc(n2)N(CCC#N)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J11 compound treatment 0.72 0.49 5.14 0.662 0.433 5.18 7.3037 1.0 3041828 ChemDiv3_015345 COc1ccc(Cl)cc1S(=O)(=O)N2CCC(CC2)c3nnc(o3)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J12 compound treatment 0.313 0.0829 0.87 0.302 0.0733 0.88 1.2354 1.0 3124584 ChemDiv3_015346 O=C(CC1Oc2ccccc2NC1=O)N3CCN(CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J13 compound treatment 0.379 0.149 1.56 0.437 0.208 2.49 2.8677 0.9748 3124585 ChemDiv3_015347 O=C(CCc1nc2cccnc2n1Cc3cccs3)N4CCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J14 compound treatment 0.113 -0.117 -1.23 0.128 -0.101 -1.21 -1.7219 -0.9999 3041830 ChemDiv3_015348 COc1ccc2ncc(C(=O)c3ccccc3)c(N4CCCCC4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J15 compound treatment 0.582 0.352 3.7 0.467 0.238 2.85 4.6291 0.9918 1181891 ChemDiv3_015349 Cc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2N4CCN(CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J16 compound treatment 0.206 -0.0241 -0.25 0.185 -0.0437 -0.52 -0.549 -0.9446 3041832 ChemDiv3_015350 O=C(NCc1ccco1)C2CCN(CC2)c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J17 compound treatment 0.183 -0.0471 -0.49 0.224 -0.00472 -0.06 -0.3899 -0.7827 3124586 ChemDiv3_015351 CN(C)CCN(Cc1ccco1)C(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J18 compound treatment 0.087 -0.143 -1.5 0.085 -0.144 -1.72 -2.2788 -0.9978 3041834 ChemDiv3_015352 OC(=O)CCC(=O)n1ncc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J19 compound treatment 0.093 -0.137 -1.44 0.1 -0.129 -1.54 -2.1073 -0.9994 3124587 ChemDiv3_015353 CN1CCSc2ccc(cc12)C(=O)NCCCN3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J20 compound treatment 0.495 0.265 2.78 0.451 0.222 2.66 3.8476 0.9997 3124588 ChemDiv3_015354 O=C(Cn1ncc2ccccc12)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J21 compound treatment 0.114 -0.116 -1.22 0.112 -0.117 -1.4 -1.8499 -0.9977 3041836 ChemDiv3_015355 CCN1CCSc2ccc(cc12)C(=O)NCCCN3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J22 compound treatment 0.319 0.0889 0.93 0.307 0.0783 0.94 1.3223 1.0 3124589 ChemDiv3_015356 CC1CCC(CC1)NC(=O)Nc2ccc3SCC(=O)N(Cc4ccc(C)cc4)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J23 mock treatment 0.267 0.0369 0.39 0.207 -0.0217 -0.26 0.0901 0.1932 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 J24 mock treatment 0.234 0.00388 0.04 0.236 0.00728 0.09 0.0904 0.9399 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K01 compound treatment 0.173 -0.0571 -0.6 0.164 -0.0647 -0.77 -0.9718 -0.992 3124590 ChemDiv3_015357 O=C(NC1(CCCCC1)C(=O)Nc2ccc3OCOc3c2)/C=C\c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K02 compound treatment 0.165 -0.0651 -0.68 0.146 -0.0827 -0.99 -1.1835 -0.9837 3041839 ChemDiv3_015358 CCCc1nc2nc(C)cc(Cl)n2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K03 compound treatment 0.318 0.0879 0.92 0.335 0.106 1.27 1.5518 0.9876 3041840 ChemDiv3_015359 COc1ccc(cc1)C2C(C(=O)N(C)c3ccc(cc3)C(C)C)c4ccccc4C(=O)N2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K04 compound treatment 0.112 -0.118 -1.24 0.116 -0.113 -1.35 -1.8309 -0.9991 3124591 ChemDiv3_015360 CC(NCC(O)Cn1nnnc1c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K05 compound treatment 1.023 0.793 8.33 0.979 0.75 8.98 12.2358 0.9993 3041842 ChemDiv3_015361 C1CCC(CC1)Nc2c(nc3cnccn23)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K06 compound treatment 0.188 -0.0421 -0.44 0.189 -0.0397 -0.48 -0.6489 -0.9994 3124592 ChemDiv3_015362 Cc1nc2sccn2c(=O)c1S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K07 compound treatment 0.298 0.0679 0.71 0.262 0.0333 0.4 0.7856 0.9622 3124593 ChemDiv3_015363 COc1ccccc1CNC(=O)c2ccc3c(=O)[nH]c4c(nnn4c3c2)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K08 compound treatment 0.115 -0.115 -1.21 0.136 -0.0927 -1.11 -1.6394 -0.9991 3041877 ChemDiv3_015364 CCOC(=O)c1nnc(Cc2ccccc2OC)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K09 compound treatment 0.227 -0.00312 -0.03 0.199 -0.0297 -0.36 -0.2746 -0.7691 3041879 ChemDiv3_015365 Fc1ccc(CNC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K10 compound treatment 0.081 -0.149 -1.57 0.086 -0.143 -1.71 -2.3149 -0.9991 3041880 ChemDiv3_015366 C(N1CCc2ccccc2C1)c3nnc(o3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K11 compound treatment 0.127 -0.103 -1.08 0.132 -0.0967 -1.16 -1.5841 -0.9995 3041881 ChemDiv3_015367 NC1=NC(Cc2ccccc2)CC(=O)N1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K12 compound treatment 0.093 -0.137 -1.44 0.103 -0.126 -1.5 -2.082 -0.9998 3041883 ChemDiv3_015368 C(N1CCCCCC1)c2nnc(o2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K13 compound treatment 0.084 -0.146 -1.53 0.081 -0.148 -1.77 -2.3349 -0.9975 3041884 ChemDiv3_015369 CCCn1cnc2cc(NCc3ccncc3)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K14 compound treatment 0.265 0.0349 0.37 0.258 0.0293 0.35 0.5067 0.9998 3041885 ChemDiv3_015370 CCNc1c(NS(=O)(=O)c2ccc(cc2)C3CCCCC3)c(=O)oc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K15 compound treatment 0.239 0.00887 0.09 0.182 -0.0467 -0.56 -0.3293 -0.5812 3124702 ChemDiv3_015371 CCc1ccc(CN2C(C(=O)NCCc3ccccc3)c4ccccc4C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K16 compound treatment 0.352 0.122 1.28 0.367 0.138 1.65 2.075 0.992 3041887 ChemDiv3_015372 CN(Cc1ccccc1)C(=O)c2ccc(cc2)N3CCCC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K17 compound treatment 0.29 0.0599 0.63 0.266 0.0373 0.45 0.7601 0.9858 3124703 ChemDiv3_015373 CC(C)(C)C(=O)Cn1c(=O)n(CC2CCC(CC2)C(=O)NCc3ccccc3)c(=O)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K18 compound treatment 0.295 0.0649 0.68 0.313 0.0843 1.01 1.1948 0.9818 3041889 ChemDiv3_015374 OC(=O)C1CCN(CC1)c2nc3ncccc3nc2c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K19 compound treatment 0.209 -0.0211 -0.22 0.229 2.81E-4 0.0 -0.1545 -0.6963 3124704 ChemDiv3_015375 CCCN1CCN(CCNC(=O)Nc2ccccc2OC)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K20 compound treatment 0.604 0.374 3.93 0.492 0.263 3.15 5.004 0.994 3041891 ChemDiv3_015376 N(c1ccccc1)c2cnccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K21 compound treatment 0.21 -0.0201 -0.21 0.2 -0.0287 -0.34 -0.3924 -0.9728 3124705 ChemDiv3_015377 C1COc2cc(Nc3c(nc4ccccn34)c5ccccc5)ccc2O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K22 compound treatment 0.251 0.0209 0.22 0.221 -0.00772 -0.09 0.0897 0.3772 3041893 ChemDiv3_015378 O=C(NN1CCOCC1)c2cccc3CN(Cc4cccnc4)C(=O)c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K23 mock treatment 0.179 -0.0511 -0.54 0.164 -0.0647 -0.77 -0.9272 -0.984 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 K24 mock treatment 0.181 -0.0491 -0.52 0.231 0.00228 0.03 -0.3455 -0.6688 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L01 compound treatment 0.326 0.0959 1.01 0.279 0.0503 0.6 1.1374 0.9697 3124706 ChemDiv3_015379 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cccc4CN(C5CCCCC5)C(=O)c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L02 compound treatment 1.357 1.13 11.84 1.375 1.15 13.71 18.0664 0.9973 3124707 ChemDiv3_015380 Clc1ccc2n(CCCC(=O)NCCc3ccccc3)nc(c4ccccc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L03 compound treatment 0.318 0.0879 0.92 0.296 0.0673 0.8 1.2218 0.9977 3041895 ChemDiv3_015381 CC1CC(C)CN(C1)C(=O)c2ccc3S(=O)c4ccccc4C(=O)N(Cc5ccccc5)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L04 compound treatment 0.324 0.0939 0.99 0.277 0.0483 0.58 1.1056 0.9676 3124708 ChemDiv3_015382 COc1ccc(cc1)C2CC(=O)N(CC(=O)N3CCOCC3)c4ccccc4S2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L05 compound treatment 0.547 0.317 3.33 0.492 0.263 3.15 4.5807 0.9996 3041897 ChemDiv3_015383 O=C(NC1CCCC1)c2cnc(nc2)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L06 compound treatment 0.836 0.606 6.36 0.777 0.548 6.56 9.1381 0.9999 3124709 ChemDiv3_015384 CCc1ccc(NC(=O)Cn2c(=O)n(C3CCCCC3)c(=O)c4cccnc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L07 compound treatment 0.369 0.139 1.46 0.402 0.173 2.07 2.4973 0.9852 3124710 ChemDiv3_015385 COc1cccc(c1)c2cc([nH]n2)C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L08 compound treatment 0.158 -0.0721 -0.76 0.125 -0.104 -1.24 -1.4131 -0.972 3041900 ChemDiv3_015386 CN(CCNC(=O)Cn1ncc2COc3ccccc3-c21)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L09 compound treatment 0.67 0.44 4.62 0.711 0.482 5.77 7.3469 0.9939 3124711 ChemDiv3_015387 Cc1ccc(C)c(NC(=O)c2nccnc2COC(=O)c3cccc(F)c3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L10 compound treatment 0.212 -0.0181 -0.19 0.173 -0.0557 -0.67 -0.606 -0.8741 3041902 ChemDiv3_015388 COc1ccc(Nc2nc(no2)c3ccc(OC)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L11 compound treatment 0.163 -0.0671 -0.7 0.146 -0.0827 -0.99 -1.1983 -0.9862 3041943 ChemDiv3_015389 COc1ccc(cc1)c2nnc(o2)C3CCN(CC3)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L12 compound treatment 0.266 0.0359 0.38 0.232 0.00328 0.04 0.2942 0.7766 3041944 ChemDiv3_015390 CCN(Cc1ccccc1)C(=O)CC2Oc3ccccc3NC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L13 compound treatment 0.321 0.0909 0.95 0.337 0.108 1.3 1.591 0.9887 3041946 ChemDiv3_015391 O=C(CCc1nc2cccnc2n1Cc3cccs3)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L14 compound treatment 0.177 -0.0531 -0.56 0.141 -0.0877 -1.05 -1.1366 -0.9563 3041948 ChemDiv3_015392 Cc1ccc(cc1C)C(=O)c2cnc3cc4OCOc4cc3c2N5CCC(CC5)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L15 compound treatment 0.181 -0.0491 -0.52 0.17 -0.0587 -0.7 -0.8616 -0.9885 3041949 ChemDiv3_015393 Cn1cc(c(=O)c2cc(F)ccc12)S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L16 compound treatment 0.282 0.0519 0.54 0.266 0.0373 0.45 0.7007 0.9951 3041950 ChemDiv3_015394 CCC(C(=O)Nc1ccccc1OC)n2c(cc3occc23)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L17 compound treatment 0.406 0.176 1.85 0.387 0.158 1.89 2.6452 0.9999 3124712 ChemDiv3_015395 CCOC(=O)N1CCN(CC1)C(=O)c2ccc3SCCN(Cc4ccccc4)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L18 compound treatment 0.277 0.0469 0.49 0.282 0.0533 0.64 0.7989 0.9918 3041952 ChemDiv3_015396 CC1CCN(CC1)c2nnc(NC(=O)c3csc4CCCCc34)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L19 compound treatment 0.112 -0.118 -1.24 0.121 -0.108 -1.29 -1.7886 -0.9998 3124713 ChemDiv3_015397 CN1CCSc2ccc(cc12)C(=O)NCCN3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L20 compound treatment 0.261 0.0309 0.32 0.291 0.0623 0.75 0.7562 0.9305 3041955 ChemDiv3_015398 O=C(Cn1ncc2ccccc12)N3CCN(CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L21 compound treatment 0.429 0.199 2.09 0.399 0.17 2.04 2.9175 0.9999 3124714 ChemDiv3_015399 COC(CNC(=O)c1ccc2SCCN(Cc3ccc(Cl)cc3)c2c1)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L22 compound treatment 0.259 0.0289 0.3 0.256 0.0273 0.33 0.4452 0.9993 3124715 ChemDiv3_015400 Cc1ccc(CN2C(=O)CSc3ccc(NC(=O)NCCC4=CCCCC4)cc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L23 mock treatment 0.184 -0.0461 -0.48 0.181 -0.0477 -0.57 -0.7463 -0.9967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 L24 mock treatment 0.221 -0.00912 -0.1 0.203 -0.0257 -0.31 -0.2854 -0.8854 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M01 compound treatment 0.18 -0.0501 -0.53 0.154 -0.0747 -0.89 -1.0044 -0.9681 3041957 ChemDiv3_015401 CN(C(=O)/C=C/c1ccc2OCOc2c1)C3(CCCCC3)C(=O)Nc4c(C)cccc4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M02 compound treatment 0.17 -0.0601 -0.63 0.165 -0.0637 -0.76 -0.9856 -0.9956 3124716 ChemDiv3_015402 OC(CN1CCC(Cc2ccccc2)CC1)CN3CCN(CC3)c4cccc(c4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M03 compound treatment 0.247 0.0169 0.18 0.24 0.0113 0.13 0.2208 0.991 3124717 ChemDiv3_015403 COc1ccc(cc1)C2C(C(=O)NC(C)C)c3ccccc3C(=O)N2Cc4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M04 compound treatment 0.567 0.337 3.54 0.567 0.338 4.05 5.3637 0.9978 3041959 ChemDiv3_015404 COC(=O)c1ccc(NCC(O)Cn2nnnc2c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M05 compound treatment 0.147 -0.0831 -0.87 0.157 -0.0717 -0.86 -1.2241 -1.0 3124718 ChemDiv3_015405 CCC(=O)NC(c1nc2ccccc2[nH]1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M06 compound treatment 0.465 0.235 2.47 0.479 0.25 2.99 3.8617 0.9954 3041960 ChemDiv3_015406 COC(=O)c1[nH]c2ccccc2c1C(Nc3ccc(cc3)C(=O)O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M07 compound treatment 0.107 -0.123 -1.29 0.093 -0.136 -1.62 -2.0626 -0.9936 3124719 ChemDiv3_015407 Cc1ccc2c(c1)sc3ncc(c(=O)n23)S(=O)(=O)c4ccc(F)c(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M08 compound treatment 1.025 0.795 8.35 0.971 0.742 8.88 12.1829 0.9995 3041963 ChemDiv3_015408 Clc1cccc(Cc2nnc(o2)c3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M09 compound treatment 0.224 -0.00612 -0.06 0.205 -0.0237 -0.28 -0.2462 -0.8459 3124720 ChemDiv3_015409 COc1ccc(CNC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M10 compound treatment 0.149 -0.0811 -0.85 0.144 -0.0847 -1.01 -1.3192 -0.9963 3041965 ChemDiv3_015410 C(C1CCN(Cc2nnc(o2)c3ccccc3)CC1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M11 compound treatment 0.196 -0.0341 -0.36 0.175 -0.0537 -0.64 -0.7079 -0.962 3124721 ChemDiv3_015411 CC(=O)Nc1ccc(cc1)c2cc(nc3[nH]nc(c4ccccc4)c23)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M12 compound treatment 0.673 0.443 4.65 0.66 0.431 5.16 6.9377 0.9987 3041967 ChemDiv3_015412 CCN(Cc1nnc(o1)c2ccccc2C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M13 compound treatment 0.279 0.0489 0.51 0.286 0.0573 0.69 0.8476 0.9899 3124722 ChemDiv3_015413 O=C(N1CCN(CC1)c2ccccc2)c3cc(on3)C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M14 compound treatment 0.234 0.00388 0.04 0.259 0.0303 0.36 0.285 0.7816 3042016 ChemDiv3_015414 CCNc1c(NS(=O)(=O)c2cccc(C#N)c2)c(=O)oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M15 compound treatment 0.198 -0.0321 -0.34 0.181 -0.0477 -0.57 -0.6423 -0.9685 3042017 ChemDiv3_015415 O=C(NCc1cccnc1)C2N(Cc3ccccc3)C(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M16 compound treatment 0.415 0.185 1.94 0.41 0.181 2.17 2.9066 0.9985 3042018 ChemDiv3_015416 Cc1ccc(C)c(c1)N2CCN(CC2)C(=O)c3ccc(cc3)N4CCCC4=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M17 compound treatment 0.276 0.0459 0.48 0.229 2.81E-4 0.0 0.3431 0.712 3042020 ChemDiv3_015417 COc1cc2n(CC(=O)N(CC=C)c3ccccc3)c(=O)n(Cc4ccco4)c(=O)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M18 compound treatment 0.18 -0.0501 -0.53 0.186 -0.0427 -0.51 -0.7337 -0.9999 3042021 ChemDiv3_015418 OC(=O)CCc1nnc2ccc(nn12)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M19 compound treatment 0.142 -0.0881 -0.93 0.146 -0.0827 -0.99 -1.3543 -0.9994 3042023 ChemDiv3_015419 Cc1ccc(CNC(=O)NCCN2CCN(CC2)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M20 compound treatment 0.222 -0.00812 -0.09 0.192 -0.0367 -0.44 -0.371 -0.829 3042024 ChemDiv3_015420 CCCC(N1Cc2ccccc2C1=O)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M21 compound treatment 0.253 0.0229 0.24 0.269 0.0403 0.48 0.5107 0.9483 3124723 ChemDiv3_015421 CN1C(C(C(=O)Nc2ccc(F)c(Cl)c2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M22 compound treatment 0.202 -0.0281 -0.3 0.231 0.00228 0.03 -0.1896 -0.639 3124724 ChemDiv3_015422 COC(CNC(=O)c1cccc2CN(Cc3cccnc3)C(=O)c21)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M23 mock treatment 0.179 -0.0511 -0.54 0.186 -0.0427 -0.51 -0.7411 -0.9997 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 M24 mock treatment 0.232 0.00188 0.02 0.249 0.0203 0.24 0.1855 0.762 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N01 compound treatment 0.231 8.75E-4 0.01 0.224 -0.00472 -0.06 -0.0334 -0.5843 3042027 ChemDiv3_015423 COc1ccc(cc1)N2Cc3cccc(C(=O)NCCC4=CCCCC4)c3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N02 compound treatment 1.234 1.0 10.54 1.241 1.01 12.11 16.0193 0.9976 3124725 ChemDiv3_015424 Clc1ccc2n(CCCC(=O)N3CCOCC3)nc(c4ccccc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N03 compound treatment 0.581 0.351 3.69 0.564 0.335 4.01 5.4423 0.9991 3042029 ChemDiv3_015425 Cc1cc(C(=O)Nc2ccc(Cl)cc2)n(n1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N04 compound treatment 0.334 0.104 1.09 0.324 0.0953 1.14 1.5775 0.9998 3124726 ChemDiv3_015426 Cc1ccc(cc1)S(=O)(=O)c2cnc(SCC(=O)N3CCCc4ccccc34)[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N05 compound treatment 0.243 0.0129 0.14 0.253 0.0243 0.29 0.301 0.9395 3042031 ChemDiv3_015427 O=C(N1CCCC1)c2cnc(nc2)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N06 compound treatment 1.44 1.21 12.71 1.425 1.2 14.31 19.1059 0.9982 3124727 ChemDiv3_015428 CC(C)CCn1c(=O)n(Cc2cccc(F)c2)c3ncccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N07 compound treatment 0.532 0.302 3.17 0.473 0.244 2.92 4.3085 0.9992 3042033 ChemDiv3_015429 CC(C)N(Cc1nc(no1)c2ccccc2)C(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N08 compound treatment 0.322 0.0919 0.96 0.333 0.104 1.25 1.5645 0.9919 3124973 ChemDiv3_015430 CCCC(CCC)C(=O)N1CCNc2ccccc2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N09 compound treatment 0.074 -0.156 -1.64 0.071 -0.158 -1.89 -2.4938 -0.9976 3124837 ChemDiv3_015431 Cc1nn2CN(Cc3ccc(Cl)cc3)CNc2c1c4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N10 compound treatment 0.526 0.296 3.11 0.518 0.289 3.46 4.6447 0.9986 3042035 ChemDiv3_015432 COc1ccc(cc1)c2noc(n2)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N11 compound treatment 0.243 0.0129 0.14 0.236 0.00728 0.09 0.1572 0.9774 3124838 ChemDiv3_015433 COc1ccccc1c2nnc(o2)C3CCN(CC3)C(=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N12 compound treatment 0.182 -0.0481 -0.51 0.175 -0.0537 -0.64 -0.8119 -0.9929 3042037 ChemDiv3_015434 CC(C)NC(=O)CC1Oc2ccc(Cl)cc2NC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N13 compound treatment 0.809 0.579 6.08 0.739 0.51 6.11 8.6161 1.0 3124839 ChemDiv3_015435 CCc1ccc(NC(=O)CCc2nc3cccnc3n2Cc4cccs4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N14 compound treatment 0.192 -0.0381 -0.4 0.188 -0.0407 -0.49 -0.6276 -0.9953 3124840 ChemDiv3_015436 CN1CCN(CC1)c2c(cnc3cc4OCOc4cc23)C(=O)c5ccc(C)c(C)c5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N15 compound treatment 0.205 -0.0251 -0.26 0.188 -0.0407 -0.49 -0.5311 -0.9585 3042040 ChemDiv3_015437 CCc1ccc(cc1)S(=O)(=O)c2cn(C)c3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N16 compound treatment 1.375 1.14 12.02 1.391 1.16 13.91 18.3355 0.9974 3042041 ChemDiv3_015438 COC(=O)c1cc2ccsc2n1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N17 compound treatment 0.47 0.24 2.52 0.44 0.211 2.53 3.5689 1.0 3042184 ChemDiv3_015439 O=C(N1CCOCC1)c2ccc3SCCN(Cc4ccccc4)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N18 compound treatment 0.293 0.0629 0.66 0.266 0.0373 0.45 0.7823 0.9818 3042099 ChemDiv3_015440 CN1C(=O)CSc2ccc(NC(=O)Nc3ccc(C)cc3)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N19 compound treatment 0.213 -0.0171 -0.18 0.252 0.0233 0.28 0.0698 0.2105 3042101 ChemDiv3_015441 CCN1CCSc2ccc(cc12)C(=O)NCc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N20 compound treatment 0.513 0.283 2.97 0.446 0.217 2.6 3.939 0.9978 3042102 ChemDiv3_015442 O=C(Cn1ncc2ccccc12)N3CCc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N21 compound treatment 0.237 0.00687 0.07 0.211 -0.0177 -0.21 -0.0988 -0.4414 3042103 ChemDiv3_015443 COC(CNC(=O)CC1C(=O)N(Cc2ccccc2)C(C)c3nc4ccccc4n13)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N22 compound treatment 0.692 0.462 4.85 0.695 0.466 5.58 7.3749 0.9976 3042105 ChemDiv3_015444 Clc1cccc(c1)c2cc(NC(=O)Cn3ncc4ccccc34)on2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N23 mock treatment 0.232 0.00188 0.02 0.239 0.0103 0.12 0.1009 0.81 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 N24 mock treatment 0.235 0.00487 0.05 0.219 -0.00972 -0.12 -0.046 -0.3622 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O01 compound treatment 0.176 -0.0541 -0.57 0.182 -0.0467 -0.56 -0.7972 -1.0 3042106 ChemDiv3_015445 O=C(NC1CCCC1)C2(CCCCC2)N(Cc3cccs3)C(=O)c4cnccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O02 compound treatment 0.173 -0.0571 -0.6 0.188 -0.0407 -0.49 -0.7687 -0.9947 3042108 ChemDiv3_015446 Clc1ccc(OCC(=O)NCCCN2CCN(CC2)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O03 compound treatment 0.16 -0.0701 -0.74 0.168 -0.0607 -0.73 -1.0345 -1.0 3124841 ChemDiv3_015447 COc1ccc2[nH]c3CCN(C)Cc3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O04 compound treatment 0.174 -0.0561 -0.59 0.187 -0.0417 -0.5 -0.7698 -0.9966 3042109 ChemDiv3_015448 O=C(NCc1ccccn1)c2nnc(o2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O05 compound treatment 0.138 -0.0921 -0.97 0.14 -0.0887 -1.06 -1.4347 -0.9989 3124842 ChemDiv3_015449 COC(=O)CNc1c(nc2ccccn12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O06 compound treatment 0.56 0.33 3.46 0.588 0.359 4.3 5.4894 0.9943 3124843 ChemDiv3_015450 CCOC(=O)CSC(c1c([nH]c2ccccc12)C(=O)OC)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O07 compound treatment 0.19 -0.0401 -0.42 0.173 -0.0557 -0.67 -0.7694 -0.9755 3042112 ChemDiv3_015451 Cc1ccc(CN2CCc3[nH]c(=O)[nH]c(=O)c3C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O08 compound treatment 0.267 0.0369 0.39 0.245 0.0163 0.19 0.4116 0.9494 3124844 ChemDiv3_015452 CCOC(=O)Cc1nnc(o1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O09 compound treatment 0.199 -0.0311 -0.33 0.174 -0.0547 -0.65 -0.6941 -0.9485 3042115 ChemDiv3_015453 Cc1ccc(CNC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O10 compound treatment 0.191 -0.0391 -0.41 0.181 -0.0477 -0.57 -0.6943 -0.987 3124845 ChemDiv3_015454 CNc1c(NS(=O)(=O)c2ccc(Cl)cc2)c(=O)oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O11 compound treatment 0.259 0.0289 0.3 0.266 0.0373 0.45 0.5298 0.9823 3124846 ChemDiv3_015455 COc1ccc(cc1OC)c2cc(nc3[nH]nc(c4ccccc4)c23)C(=O)NCCc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O12 compound treatment 0.172 -0.0581 -0.61 0.174 -0.0547 -0.65 -0.8946 -0.9994 3042117 ChemDiv3_015456 Cc1ccccc1c2nnc(CN3CCCC3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O13 compound treatment 0.208 -0.0221 -0.23 0.225 -0.00372 -0.04 -0.1958 -0.8275 3042119 ChemDiv3_015457 Cc1ccccc1Nc2c(nc3sccn23)c4ccc(O)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O14 compound treatment 0.237 0.00687 0.07 0.247 0.0183 0.22 0.2057 0.8931 3124847 ChemDiv3_015458 Cc1ccc(CN2CCN(CC(=O)NCc3ccc4OCOc4c3)C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O15 compound treatment 0.171 -0.0591 -0.62 0.184 -0.0447 -0.54 -0.8174 -0.9972 3124848 ChemDiv3_015459 O=C(NCc1cccnc1)C2N(C3CCCC3)C(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O16 compound treatment 0.268 0.0379 0.4 0.267 0.0383 0.46 0.6051 0.9975 3042122 ChemDiv3_015460 COc1ccc(cc1)C2NC(=O)c3[nH]nc(c23)c4cccc(OC)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O17 compound treatment 0.102 -0.128 -1.35 0.103 -0.126 -1.5 -2.0151 -0.9985 3124849 ChemDiv3_015461 Cc1cccc(NC(=O)NC2CCCCC2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O18 compound treatment 0.202 -0.0281 -0.3 0.216 -0.0127 -0.15 -0.3165 -0.9524 3124850 ChemDiv3_015462 OC(=O)C(CS(=O)(=O)Cc1ccccc1)N2Cc3ccccc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O19 compound treatment 0.165 -0.0651 -0.68 0.145 -0.0837 -1.0 -1.1919 -0.9827 3042124 ChemDiv3_015463 CCc1ccccc1NC(=O)NCCN2CCN(CC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O20 compound treatment 0.996 0.766 8.04 0.912 0.683 8.18 11.4684 1.0 3042185 ChemDiv3_015464 CSc1ccc(CCNC(=O)c2cccc3CN(CC4CCCO4)C(=O)c32)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O21 compound treatment 0.326 0.0959 1.01 0.27 0.0413 0.49 1.0613 0.9462 3042187 ChemDiv3_015465 CC1CCCN(C1)C(=O)C2C(N(C)C(=O)c3ccccc23)c4c[nH]c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O22 compound treatment 0.205 -0.0251 -0.26 0.207 -0.0217 -0.26 -0.3703 -1.0 3042189 ChemDiv3_015466 O=C(N1CCN(Cc2ccccc2)CC1)c3cccc4CN(Cc5cccnc5)C(=O)c43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O23 mock treatment 0.156 -0.0741 -0.78 0.204 -0.0247 -0.3 -0.7596 -0.9121 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 O24 mock treatment 0.242 0.0119 0.12 0.243 0.0143 0.17 0.209 0.988 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P01 compound treatment 0.174 -0.0561 -0.59 0.16 -0.0687 -0.82 -0.9982 -0.9867 3042190 ChemDiv3_015467 FC(F)(F)c1cccc(NC(=O)C2CCC(Cn3c(=O)[nH]c4ccsc4c3=O)CC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P02 compound treatment 0.74 0.51 5.36 0.726 0.497 5.95 7.9937 0.9986 3124851 ChemDiv3_015468 CCOC(=O)C1CCN(CC1)C(=O)CCCn2nc(c3ccccc3)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P03 compound treatment 0.153 -0.0771 -0.81 0.181 -0.0477 -0.57 -0.9765 -0.9853 3042192 ChemDiv3_015469 CCCNC(=O)C1CCN(CC1)c2cc(C)nc3c(c(C)nn23)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P04 compound treatment 0.205 -0.0251 -0.26 0.212 -0.0167 -0.2 -0.328 -0.9907 3124852 ChemDiv3_015470 O=C(NCc1cccnc1)c2cccc3sc(nc23)N4CCCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P05 compound treatment 0.312 0.0819 0.86 0.319 0.0903 1.08 1.3718 0.9936 3042194 ChemDiv3_015471 CCCNC(=O)c1cnc(nc1)N2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P06 compound treatment 0.241 0.0109 0.11 0.215 -0.0137 -0.16 -0.0353 -0.1765 3124853 ChemDiv3_015472 CN(C1CCCCC1)C(=O)Cn2ncc3COc4ccccc4-c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P07 compound treatment 0.19 -0.0401 -0.42 0.172 -0.0567 -0.68 -0.7778 -0.9737 3042197 ChemDiv3_015473 CC(=O)N1CCc2cc(ccc12)C(O)CN3CCN(CC3)C4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P08 compound treatment 0.981 0.751 7.89 0.93 0.701 8.39 11.5093 0.9995 3124854 ChemDiv3_015474 COc1ccc(cc1)c2noc(n2)N3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P09 compound treatment 0.175 -0.0551 -0.58 0.183 -0.0457 -0.55 -0.7962 -0.9996 3124855 ChemDiv3_015475 CCOc1ccc(NC(=O)c2ccnc(c2)N3CCC(CC3)C(=O)N4CCOCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P10 compound treatment 0.142 -0.0881 -0.93 0.167 -0.0617 -0.74 -1.1766 -0.9937 3042199 ChemDiv3_015476 CCN1CCCC1CNCc2c(C(=O)O)n(Cc3ccccc3C)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P11 compound treatment 0.223 -0.00712 -0.07 0.289 0.0603 0.72 0.4571 0.6304 3124856 ChemDiv3_015477 COc1ccc(cc1)c2nnc(o2)C3CCN(CC3)C(=O)c4c(F)cccc4F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P12 compound treatment 0.187 -0.0431 -0.45 0.28 0.0513 0.61 0.1136 0.1489 3124857 ChemDiv3_015478 Cc1ccnc(NC(=O)Cn2ncc3COc4ccc(C)cc4-c32)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P13 compound treatment 1.167 0.937 9.84 1.064 0.835 9.99 14.0243 1.0 3042202 ChemDiv3_015479 CC(C)NC(=O)c1cc2CSc3ccccc3-c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P14 compound treatment 0.249 0.0189 0.2 0.278 0.0493 0.59 0.5571 0.8956 3124858 ChemDiv3_015480 CCN1CCN(CC1)c2c(cnc3ccc(C)cc23)C(=O)c4ccc(C)c(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P15 compound treatment 0.252 0.0219 0.23 0.27 0.0413 0.49 0.5117 0.9394 3042204 ChemDiv3_015481 CCc1ccc(cc1)S(=O)(=O)c2cn(CC)c3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P16 compound treatment 0.221 -0.00912 -0.1 0.218 -0.0107 -0.13 -0.1584 -0.9897 3124859 ChemDiv3_015482 CC(C)CCNC(=O)C1CCN(CC1)C(=O)c2cc3sccc3n2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P17 compound treatment 0.206 -0.0241 -0.25 0.224 -0.00472 -0.06 -0.2191 -0.844 3042205 ChemDiv3_015483 O=C(N1CCN(CC1)c2ccccn2)c3ccc4SCCN(Cc5ccccc5)c4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P18 compound treatment 0.186 -0.0441 -0.46 0.222 -0.00672 -0.08 -0.3845 -0.8176 3124860 ChemDiv3_015484 CN1C(=O)CSc2ccc(NC(=O)N3CCc4ccccc34)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P19 compound treatment 0.482 0.252 2.65 0.517 0.288 3.45 4.3095 0.9914 3124861 ChemDiv3_015485 CCN1CCSc2ccc(cc12)C(=O)Nc3ccc(CC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P20 compound treatment 0.205 -0.0251 -0.26 0.218 -0.0107 -0.13 -0.2773 -0.9451 3042207 ChemDiv3_015486 Clc1ccc(CNC(=O)Cn2ncc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P21 compound treatment 0.228 -0.00212 -0.02 0.204 -0.0247 -0.3 -0.2249 -0.7583 3124862 ChemDiv3_015487 Cc1ccc(Cl)cc1N2CCN(CCCNC(=O)Cn3ncc4ccsc4c3=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P22 compound treatment 0.513 0.283 2.97 0.436 0.207 2.48 3.8544 0.996 3042209 ChemDiv3_015488 CCOC(=O)c1nccn1Cc2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P23 mock treatment 0.219 -0.0111 -0.12 0.232 0.00328 0.04 -0.0549 -0.4451 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2044 P24 mock treatment 0.206 -0.0241 -0.25 0.228 -7.19E-4 -0.01 -0.1852 -0.7307 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A01 compound treatment 0.242 0.00372 0.04 0.304 -0.0196 -0.23 -0.1379 -0.5811 3042266 ChemDiv3_015489 CCOC(=O)c1nccn1CC(=O)Nc2ccccc2CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A02 compound treatment 0.233 -0.00528 -0.06 0.284 -0.0396 -0.47 -0.3739 -0.7846 3042268 ChemDiv3_015490 CC1CN(C(=O)N2CCC(CC2)C(=O)O)c3cc(Cl)ccc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A03 compound treatment 0.299 0.0607 0.64 0.328 0.00444 0.05 0.4885 0.7633 3042269 ChemDiv3_015491 COc1ccc(cc1)c2n[nH]cc2C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A04 compound treatment 0.212 -0.0263 -0.28 0.309 -0.0146 -0.17 -0.3184 -0.9754 3042271 ChemDiv3_015492 C(CNc1nc2ccccc2n3nnnc13)CN4CCC(Cc5ccccc5)CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A05 compound treatment 0.26 0.0217 0.23 0.302 -0.0216 -0.26 -0.0211 -0.0614 3042272 ChemDiv3_015493 COc1ccc(CN2C(=O)c3ccccc3CC2(C)C(=O)NC4CCCCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A06 compound treatment 0.407 0.169 1.77 0.446 0.122 1.46 2.2888 0.9955 3042273 ChemDiv3_015494 CC1CCC(CC1)NC(=O)C2CCN(CC2)c3nnc(s3)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A07 compound treatment 0.362 0.124 1.3 0.484 0.16 1.92 2.2761 0.9819 3124863 ChemDiv3_015495 O=C(N1CCCCC1)c2nsc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A08 compound treatment 0.205 -0.0333 -0.35 0.294 -0.0296 -0.35 -0.4973 -1.0 3124864 ChemDiv3_015496 COC(=O)c1ccccc1NC(=O)c2ccc3nc(sc3c2)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A09 compound treatment 0.328 0.0897 0.94 0.364 0.0404 0.48 1.0084 0.952 3042275 ChemDiv3_015497 O=C(CCC(=O)N1CCc2ccccc2C1)N3CCC(=CC3)c4c[nH]c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A10 compound treatment 0.279 0.0407 0.43 0.378 0.0544 0.65 0.7629 0.9792 3124865 ChemDiv3_015498 COc1ccc(Cl)cc1NC(=O)CN2C(=O)CSc3ncccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A11 compound treatment 0.153 -0.0853 -0.9 0.159 -0.165 -1.97 -2.0256 -0.9364 3042277 ChemDiv3_015499 C(Cc1ccccc1)NCc2c[nH]nc2c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A12 compound treatment 0.248 0.00972 0.1 0.307 -0.0166 -0.2 -0.0679 -0.3048 3124974 ChemDiv3_015500 CCOC(=O)N1CCC(CC1)NC(=O)CCCN2C(=O)CSc3nc(C)cc(C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A13 compound treatment 0.199 -0.0393 -0.41 0.295 -0.0286 -0.34 -0.5334 -0.9956 3124975 ChemDiv3_015501 O=C(N1CCOCC1)c2ccc(CN3C(=O)CCn4nccc34)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A14 compound treatment 0.103 -0.135 -1.42 0.107 -0.217 -2.59 -2.8368 -0.96 3042279 ChemDiv3_015502 CCC(Sc1nc2ccncc2[nH]1)C(=O)N(Cc3ccccc3)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A15 compound treatment 0.096 -0.142 -1.49 0.113 -0.211 -2.52 -2.838 -0.9689 3124976 ChemDiv3_015503 Cc1ccc(C)n1c2nnc(s2)N3CCCC(C3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A16 compound treatment 0.323 0.0847 0.89 0.402 0.0784 0.94 1.2928 0.9996 3124977 ChemDiv3_015504 CCN(Cc1ccccc1)C(=O)Cn2cc3CCCCCCc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A17 compound treatment 0.316 0.0777 0.82 0.423 0.0994 1.19 1.4184 0.9831 3042281 ChemDiv3_015505 COc1ccc2c(c1)sc3ncc(C(=O)NCC(C)c4ccccc4)c(=O)n23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A18 compound treatment 0.299 0.0607 0.64 0.434 0.11 1.32 1.3852 0.9442 3124978 ChemDiv3_015506 CNC(=O)C(C)n1c(C)c2cnn(c3ccccc3)c(=O)c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A19 compound treatment 0.951 0.713 7.49 1.023 0.699 8.37 11.2104 0.9985 3042283 ChemDiv3_015507 CCOC(=O)c1oc2ccc3OC4(CCCC4)CC(=O)c3c2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A20 compound treatment 0.051 -0.187 -1.97 0.047 -0.277 -3.31 -3.7306 -0.9691 3124979 ChemDiv3_015508 OC(=O)c1ccc(s1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A21 compound treatment 0.373 0.135 1.41 0.444 0.12 1.44 2.0194 1.0 3124980 ChemDiv3_015509 CCCNC(=O)c1ccc(cc1)n2c(C)cc3CCCCc32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A22 compound treatment 0.288 0.0497 0.52 0.384 0.0604 0.72 0.8805 0.9872 3042285 ChemDiv3_015510 Clc1ccccc1NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A23 mock treatment 0.257 0.0187 0.2 0.345 0.0214 0.26 0.3204 0.9914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 A24 mock treatment 0.356 0.118 1.24 0.341 0.0174 0.21 1.0218 0.8149 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B01 compound treatment 0.198 -0.0403 -0.42 0.268 -0.0556 -0.66 -0.7692 -0.9762 3124981 ChemDiv3_015511 Cc1ccc(NC(=O)CCS(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B02 compound treatment 0.55 0.312 3.27 0.631 0.307 3.68 4.9159 0.9983 3042287 ChemDiv3_015512 O=C(Nc1ccccc1)N2CCn3c2nc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B03 compound treatment 0.226 -0.0123 -0.13 0.368 0.0444 0.53 0.2847 0.5205 3124982 ChemDiv3_015513 CN(Cc1ccccc1)C(=O)CCc2c(C)nc3n(nc(C)c3c2C)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B04 compound treatment 0.17 -0.0683 -0.72 0.206 -0.118 -1.41 -1.5017 -0.9511 3042289 ChemDiv3_015514 C(CSc1nc2ccccc2[nH]1)Oc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B05 compound treatment 0.328 0.0897 0.94 0.43 0.106 1.27 1.5668 0.989 3124983 ChemDiv3_015515 CCOc1cc(CCn2cnc3c4cc(C)ccc4[nH]c3c2=O)ccc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B06 compound treatment 0.153 -0.0853 -0.9 0.178 -0.146 -1.74 -1.8648 -0.9522 3124984 ChemDiv3_015516 CCCCC1CCC(CC1)C(=O)Nc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B07 compound treatment 0.107 -0.131 -1.38 0.102 -0.222 -2.65 -2.8494 -0.9536 1726214 ChemDiv3_015517 CC(C)N(C(=O)CSc1nc2cc(C)ccc2[nH]1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B08 compound treatment 0.371 0.133 1.39 0.457 0.133 1.6 2.1145 0.9977 3042346 ChemDiv3_015518 CSc1ncc(Cl)c(n1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B09 compound treatment 0.123 -0.115 -1.21 0.128 -0.196 -2.34 -2.5106 -0.953 3042348 ChemDiv3_015519 Cc1ccc(OCCCn2cnc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B10 compound treatment 0.361 0.123 1.29 0.481 0.157 1.88 2.2433 0.9829 3042349 ChemDiv3_015520 CCCn1c(SCc2nc(no2)c3ccc(OC)cc3)nnc1c4ccncc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B11 compound treatment 0.318 0.0797 0.84 0.42 0.0964 1.15 1.4079 0.9876 3042351 ChemDiv3_015521 Cc1ccc(Cn2c(CNC(=O)c3ccccc3)nc4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B12 compound treatment 0.187 -0.0513 -0.54 0.262 -0.0616 -0.74 -0.9017 -0.9882 3042352 ChemDiv3_015522 O=C(CCc1nc(no1)c2ccccc2)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B13 compound treatment 0.173 -0.0653 -0.69 0.247 -0.0766 -0.92 -1.1325 -0.9898 3042354 ChemDiv3_015523 Brc1ccc(cc1)C(=O)CCC(=O)Nc2cccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B14 compound treatment 0.177 -0.0613 -0.64 0.248 -0.0756 -0.9 -1.0944 -0.9861 3124985 ChemDiv3_015524 Oc1nc(SCc2ccccc2)nc3[nH]cnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B15 compound treatment 0.515 0.277 2.91 0.657 0.333 3.99 4.876 0.9879 3124986 ChemDiv3_015525 Cc1cc(C)c2c(CC(=O)Nc3sc4CCCc4c3C(=O)NCC5CCCO5)coc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B16 compound treatment 0.24 0.00172 0.02 0.326 0.00244 0.03 0.0334 0.9734 3042356 ChemDiv3_015526 Clc1ccccc1Cn2c(nc3ccccc23)C4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B17 compound treatment 0.315 0.0767 0.81 0.364 0.0404 0.48 0.9119 0.9702 3124987 ChemDiv3_015527 CC(C)N(Cc1cc2ccc(C)cc2nc1O)C(=O)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B18 compound treatment 0.316 0.0777 0.82 0.428 0.104 1.25 1.4607 0.9787 1188414 ChemDiv3_015528 CCCc1cc(=O)[nH]c(Nc2ccc(CC)cc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B19 compound treatment 0.26 0.0217 0.23 0.347 0.0234 0.28 0.3596 0.9948 3124988 ChemDiv3_015529 COc1ccc(CNc2nc3[nH]c4CCCc4c(=O)n3n2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B20 compound treatment 0.398 0.16 1.68 0.429 0.105 1.26 2.0782 0.9901 1304801 ChemDiv3_015530 Cc1ccc2[nH]c3C(CCCc3c2c1)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B21 compound treatment 0.309 0.0707 0.74 0.405 0.0814 0.97 1.2142 0.991 3124989 ChemDiv3_015531 COc1ccc(cc1)S(=O)(=O)N2CCC(CC2)n3c(=O)[nH]c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B22 compound treatment 0.229 -0.00928 -0.1 0.272 -0.0516 -0.62 -0.5052 -0.8088 1180984 ChemDiv3_015532 CC(=O)OC1(CN2CCC1c3ccccc23)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B23 mock treatment 0.286 0.0477 0.5 0.375 0.0514 0.62 0.7896 0.9948 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 B24 mock treatment 0.24 0.00172 0.02 0.324 4.38E-4 0.01 0.0165 0.8761 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C01 compound treatment 0.183 -0.0553 -0.58 0.187 -0.137 -1.63 -1.5659 -0.9031 3042360 ChemDiv3_015533 CCOC(=O)c1nccn1CC(=O)N(C)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C02 compound treatment 0.142 -0.0963 -1.01 0.156 -0.168 -2.0 -2.1326 -0.9498 3124990 ChemDiv3_015534 CC1CN(C(=O)n2ccnc2)c3ccccc3S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C03 compound treatment 0.216 -0.0223 -0.23 0.262 -0.0616 -0.74 -0.6863 -0.888 3042362 ChemDiv3_015535 COc1ccc(cc1)c2n[nH]cc2C(=O)NCCC(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C04 compound treatment 1.118 0.88 9.24 1.204 0.88 10.53 13.9819 0.9979 3124991 ChemDiv3_015536 CCN(c1ccccc1)c2nc3ccccc3n4nnnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C05 compound treatment 0.197 -0.0413 -0.43 0.348 0.0244 0.29 -0.0998 -0.1909 3124992 ChemDiv3_015537 CC1(Cc2ccccc2C(=O)N1C3CCCCC3)C(=O)NC4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C06 compound treatment 0.194 -0.0443 -0.47 0.288 -0.0356 -0.43 -0.6297 -0.999 3042364 ChemDiv3_015538 CN(Cc1ccccc1)C(=O)C2CCN(CC2)c3nnc(s3)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C07 compound treatment 0.173 -0.0653 -0.69 0.307 -0.0166 -0.2 -0.6249 -0.8756 3124993 ChemDiv3_015539 COC(=O)c1cc2sccc2n1C(C)C(=O)Nc3cc(Cl)ccc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C08 compound treatment 0.389 0.151 1.58 0.577 0.253 3.03 3.2634 0.9541 3042365 ChemDiv3_015540 Clc1ccccc1CNC(=O)c2ccc3nc(sc3c2)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C09 compound treatment 0.204 -0.0343 -0.36 0.384 0.0604 0.72 0.2567 0.3178 3124994 ChemDiv3_015541 CCOc1ccc(CNCc2c[nH]nc2c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C10 compound treatment 0.306 0.0677 0.71 0.467 0.143 1.72 1.7164 0.924 3042367 ChemDiv3_015542 Cc1ccc(NC(=O)CN2C(=O)CSc3ncccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C11 compound treatment 0.138 -0.1 -1.05 0.217 -0.107 -1.27 -1.6463 -0.9955 3041320 ChemDiv3_015543 COc1ccccc1c2n[nH]cc2CNC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C12 compound treatment 0.813 0.575 6.04 0.955 0.631 7.55 9.6102 0.9938 3041237 ChemDiv3_015544 Cc1cccc(CN2C(=O)CSc3nc(C)cc(C)c23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C13 compound treatment 0.2 -0.0383 -0.4 0.333 0.00944 0.11 -0.2045 -0.4896 3041239 ChemDiv3_015545 CNC(=O)C1CCCN(C1)c2nn3c(=O)cc(C)nc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C14 compound treatment 0.299 0.0607 0.64 0.386 0.0624 0.75 0.9792 0.9969 3041240 ChemDiv3_015546 Cc1cc(NC(=O)NC2CN(C3CCCC3)C(=O)C2)ccc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C15 compound treatment 0.186 -0.0523 -0.55 0.311 -0.0126 -0.15 -0.4945 -0.8687 3041241 ChemDiv3_015547 OC(=O)CN1C(=O)CCCc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C16 compound treatment 0.185 -0.0533 -0.56 0.287 -0.0366 -0.44 -0.705 -0.9926 3041243 ChemDiv3_015548 Cc1ccc(CNC(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C17 compound treatment 0.131 -0.107 -1.13 0.175 -0.149 -1.78 -2.0536 -0.9758 3041244 ChemDiv3_015549 Cc1ccc(CN(CC(=O)O)Cc2cn(nc2c3cccs3)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C18 compound treatment 0.3 0.0617 0.65 0.402 0.0784 0.94 1.1219 0.9837 3041246 ChemDiv3_015550 Cc1n(CCCC(=O)N2CCCCC2)c(C)c3c(=O)n(ncc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C19 compound treatment 0.319 0.0807 0.85 0.412 0.0884 1.06 1.3477 0.994 3124995 ChemDiv3_015551 Cc1c(oc2ccc3OC4(CCCC4)CC(=O)c3c12)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C20 compound treatment 0.481 0.243 2.55 0.61 0.286 3.43 4.2259 0.9894 3041247 ChemDiv3_015552 O=C(N1CCOCC1)c2ccc(s2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C21 compound treatment 0.352 0.114 1.19 0.504 0.18 2.16 2.3711 0.961 1621261 ChemDiv3_015553 COC(=O)CN1C(=O)c2cccnc2Oc3ccc(C)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C22 compound treatment 0.369 0.131 1.37 0.494 0.17 2.04 2.4127 0.9815 3124996 ChemDiv3_015554 COc1ccc(OC)c(CCNC(=O)CCc2nc3ncccc3c(=O)n2Cc4ccccc4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C23 mock treatment 0.239 7.19E-4 0.01 0.345 0.0214 0.26 0.1867 0.7276 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 C24 mock treatment 0.299 0.0607 0.64 0.401 0.0774 0.93 1.1061 0.9834 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D01 compound treatment 0.183 -0.0553 -0.58 0.268 -0.0556 -0.66 -0.8806 -0.9977 3041250 ChemDiv3_015555 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D02 compound treatment 0.181 -0.0573 -0.6 0.248 -0.0756 -0.9 -1.0647 -0.9804 3124997 ChemDiv3_015556 CCNC(=O)C1CCCN1S(=O)(=O)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D03 compound treatment 0.664 0.426 4.47 0.724 0.4 4.79 6.5494 0.9994 3041252 ChemDiv3_015557 CCOc1ccc(NC(=O)CCc2c(C)nc3n(nc(C)c3c2C)C(C)(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D04 compound treatment 0.471 0.233 2.44 0.596 0.272 3.26 4.0331 0.9899 3124998 ChemDiv3_015558 O=C(NCCSc1nnnn1c2ccccc2)C(c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D05 compound treatment 0.243 0.00472 0.05 0.353 0.0294 0.35 0.2841 0.7987 3041254 ChemDiv3_015559 COc1cc2[nH]c3c(=O)n(Cc4ccc(Cl)cc4)cnc3c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D06 compound treatment 0.059 -0.179 -1.88 0.053 -0.271 -3.24 -3.6204 -0.9668 3124999 ChemDiv3_015560 COc1ccc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)C)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D07 compound treatment 0.189 -0.0493 -0.52 0.272 -0.0516 -0.62 -0.8022 -0.9962 3125000 ChemDiv3_015561 C(Cc1ccccc1)SCc2nc3ccccc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D08 compound treatment 0.261 0.0227 0.24 0.395 0.0714 0.85 0.7731 0.8712 3041257 ChemDiv3_015562 CSc1ncc(Cl)c(n1)C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D09 compound treatment 0.135 -0.103 -1.08 0.213 -0.111 -1.32 -1.7024 -0.9951 3125248 ChemDiv3_015563 COCc1nc2ccccc2n1CC(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D10 compound treatment 0.366 0.128 1.34 0.521 0.197 2.36 2.6189 0.964 3125109 ChemDiv3_015564 CCn1c(SCc2nc(no2)c3cccs3)nnc1c4ccncc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D11 compound treatment 0.23 -0.00828 -0.09 0.353 0.0294 0.35 0.1875 0.517 3041259 ChemDiv3_015565 Clc1ccc(Cn2c(CNC(=O)c3ccccc3)nc4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D12 compound treatment 0.229 -0.00928 -0.1 0.383 0.0594 0.71 0.4339 0.6045 3125110 ChemDiv3_015566 CN(C)C(=O)CCc1nc(no1)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D13 compound treatment 0.25 0.0117 0.12 0.346 0.0224 0.27 0.2769 0.9375 3041260 ChemDiv3_015567 CC1=NCCNC2=C1C(N(C2=O)c3ccccc3)c4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D14 compound treatment 0.28 0.0417 0.44 0.33 0.00644 0.08 0.3643 0.8188 3125111 ChemDiv3_015568 Cc1nnc(SCC(=O)O)nc1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D15 compound treatment 0.259 0.0207 0.22 0.392 0.0684 0.82 0.7329 0.865 3125112 ChemDiv3_015569 CCOC(=O)c1cc(NC(=O)Nc2ccc(C)cc2C)c(C)nc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D16 compound treatment 0.268 0.0297 0.31 0.414 0.0904 1.08 0.9858 0.8754 3041262 ChemDiv3_015570 Cc1cccc(OCCn2c(nc3ccccc23)C4CCCO4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D17 compound treatment 0.244 0.00572 0.06 0.42 0.0964 1.15 0.8583 0.7429 3041321 ChemDiv3_015571 COc1ccc2nc(O)c(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D18 compound treatment 0.298 0.0597 0.63 0.447 0.123 1.48 1.4878 0.9273 3041323 ChemDiv3_015572 CCOc1ccc(Nc2cnnc(Nc3ccc(OCC)cc3)n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D19 compound treatment 0.301 0.0627 0.66 0.405 0.0814 0.97 1.1548 0.9818 3041325 ChemDiv3_015573 Cc1cc(C)n2nc(Cc3ccccc3)nc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D20 compound treatment 0.166 -0.0723 -0.76 0.215 -0.109 -1.3 -1.4553 -0.9673 1640163 ChemDiv3_015574 CNC1CCCc2c1n(C)c3ccc(Cl)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D21 compound treatment 0.365 0.127 1.33 0.515 0.191 2.29 2.5607 0.9666 3041327 ChemDiv3_015575 Fc1ccc(cc1)c2ccc(=O)[nH]n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D22 compound treatment 0.322 0.0837 0.88 0.383 0.0594 0.71 1.1246 0.9945 1568202 ChemDiv3_015576 Cc1ccc(cc1C)C(O)(C2CN3CCC2CC3)c4ccc(C)c(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D23 mock treatment 0.273 0.0347 0.36 0.381 0.0574 0.69 0.7438 0.9561 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 D24 mock treatment 0.244 0.00572 0.06 0.382 0.0584 0.7 0.5369 0.765 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E01 compound treatment 0.333 0.0947 0.99 0.459 0.135 1.62 1.8493 0.9726 3125113 ChemDiv3_015577 Clc1ccccc1CNC(=O)CCCN2C(=O)c3ccccc3Sc4ncccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E02 compound treatment 0.34 0.102 1.07 0.505 0.181 2.17 2.2904 0.9467 3041329 ChemDiv3_015578 COc1cccc(CNC(=O)c2ccc(cc2)N3CCCC3=O)c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E03 compound treatment 0.517 0.279 2.93 0.618 0.294 3.52 4.5609 0.9958 3125114 ChemDiv3_015579 CC(NC(=O)Nc1cccc(C)c1C)c2c(C)c(C)sc2n3cccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E04 compound treatment 0.39 0.152 1.59 0.559 0.235 2.82 3.1186 0.9636 3041331 ChemDiv3_015580 O=C1CCCN1CCCNc2nc3ccccc3n4nnnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E05 compound treatment 0.17 -0.0683 -0.72 0.258 -0.0656 -0.78 -1.0618 -0.999 3125115 ChemDiv3_015581 CC(C)N1CCC2(CC1)NC(=O)c3ccccc3O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E06 compound treatment 0.259 0.0207 0.22 0.394 0.0704 0.84 0.7498 0.8614 3125116 ChemDiv3_015582 O=C(C1CCN(CC1)c2nnc(s2)n3cccc3)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E07 compound treatment 0.248 0.00972 0.1 0.354 0.0304 0.36 0.3297 0.8717 3041333 ChemDiv3_015583 COC(=O)c1cc2sccc2n1C(C)C(=O)N(C)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E08 compound treatment 0.288 0.0497 0.52 0.435 0.111 1.33 1.312 0.9163 3125117 ChemDiv3_015584 COc1cc(OC)c(NC(=O)c2ccc3nc(sc3c2)N4CCOCC4)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E09 compound treatment 0.088 -0.15 -1.58 0.097 -0.227 -2.71 -3.0328 -0.9669 3041335 ChemDiv3_015585 Cc1oc(nc1CSc2ccc(Cl)cc2)c3ccc(cc3)C(=O)NCCN4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E10 compound treatment 0.169 -0.0693 -0.73 0.302 -0.0216 -0.26 -0.6969 -0.9028 3125118 ChemDiv3_015586 Cc1ccc(C)c(c1)N2CCN(CCCNC(=O)CN3C(=O)CSc4ncccc34)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E11 compound treatment 0.182 -0.0563 -0.59 0.252 -0.0716 -0.86 -1.0234 -0.9836 3125119 ChemDiv3_015587 COc1ccccc1c2n[nH]cc2CNCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E12 compound treatment 0.09 -0.148 -1.56 0.124 -0.2 -2.39 -2.7895 -0.9786 3041337 ChemDiv3_015588 CN(C(=O)Cn1c(SCc2ccc(C)cc2)nc3ccncc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E13 compound treatment 0.122 -0.116 -1.22 0.282 -0.0416 -0.5 -1.2152 -0.9216 3125120 ChemDiv3_015589 CCOC(=O)C1CCN(CC1)c2nnc(s2)N3C(=O)c4ccccc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E14 compound treatment 0.305 0.0667 0.7 0.397 0.0734 0.88 1.1168 0.9937 3125121 ChemDiv3_015590 CCc1cccc(NC(=O)NC2CN(C3CCCC3)C(=O)C2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E15 compound treatment 0.126 -0.112 -1.18 0.169 -0.155 -1.85 -2.1415 -0.9764 3041339 ChemDiv3_015591 Cc1ccc(cc1)c2cn3nc(sc3n2)N4CCCC(C4)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E16 compound treatment 0.299 0.0607 0.64 0.426 0.102 1.23 1.3176 0.9537 3125122 ChemDiv3_015592 Cc1cc(=O)n2nc(sc2n1)N3CCCC(C3)C(=O)N4CCN(CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E17 compound treatment 0.18 -0.0583 -0.61 0.256 -0.0676 -0.81 -1.0044 -0.9906 3125123 ChemDiv3_015593 O=C(NCCCN1CCCC1=O)c2ccc(Cn3c(SCc4ccccc4)nc5ccncc35)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E18 compound treatment 0.308 0.0697 0.73 0.46 0.136 1.63 1.672 0.9346 3041341 ChemDiv3_015594 CCOC(=O)C1CCN(CC1)C(=O)Cn2ncc3c(C)n(Cc4ccc(Cl)cc4)c(C)c3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E19 compound treatment 0.323 0.0847 0.89 0.461 0.137 1.64 1.7919 0.9584 3041343 ChemDiv3_015595 Cc1c(oc2ccc3OC(C)(C)CC(=O)c3c12)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E20 compound treatment 0.579 0.341 3.58 0.675 0.351 4.2 5.5036 0.9968 3125124 ChemDiv3_015596 COc1ccccc1NC(=O)c2ccc(s2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E21 compound treatment 0.511 0.273 2.86 0.63 0.306 3.67 4.6179 0.9925 3041406 ChemDiv3_015597 O=C(NC1CC1)Nc2ccc3Sc4ccccc4C(=O)N(Cc5ccccc5)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E22 compound treatment 0.514 0.276 2.9 0.607 0.283 3.39 4.4455 0.9969 3125125 ChemDiv3_015598 CC1CCN(CC1)C(=O)c2cc3CSc4cc(Cl)ccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E23 mock treatment 0.226 -0.0123 -0.13 0.318 -0.00556 -0.07 -0.1383 -0.9526 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 E24 mock treatment 0.238 -2.81E-4 0.0 0.342 0.0184 0.22 0.1539 0.6976 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F01 compound treatment 0.345 0.107 1.12 0.467 0.143 1.72 2.006 0.9787 3041408 ChemDiv3_015599 CCCN(CCC)C(=O)CCc1c(C)nc2n(nc(C)c2c1C)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F02 compound treatment 1.176 0.938 9.85 1.233 0.909 10.88 14.6579 0.9988 3125126 ChemDiv3_015600 CCOC(=O)c1oc2ccccc2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F03 compound treatment 0.21 -0.0283 -0.3 0.277 -0.0466 -0.56 -0.604 -0.9566 3125127 ChemDiv3_015601 CCN1Cc2cccc(C(=O)Nc3ccc(CC)cc3)c2C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F04 compound treatment 0.358 0.12 1.26 0.417 0.0934 1.12 1.6796 0.9983 3041263 ChemDiv3_015602 C(c1nc2c3cnn(Cc4ccccc4)c3ncn2n1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F05 compound treatment 0.25 0.0117 0.12 0.395 0.0714 0.85 0.6914 0.8007 3041265 ChemDiv3_015603 CC/1=NN(C(=O)\C1=C\c2cn(CC(O)CN3CCCCC3)c4ccccc24)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F06 compound treatment 0.233 -0.00528 -0.06 0.347 0.0234 0.28 0.1591 0.5565 3041267 ChemDiv3_015604 COc1ccc(CCNC(=O)c2nc(ncc2Cl)S(=O)(=O)C)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F07 compound treatment 0.155 -0.0833 -0.87 0.236 -0.0876 -1.05 -1.3593 -0.996 3041268 ChemDiv3_015605 CC(C)C(=O)NCCCc1nc2ccccc2n1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F08 compound treatment 0.447 0.209 2.19 0.495 0.171 2.05 3.0004 0.9994 3041270 ChemDiv3_015606 CCCSc1ncc(Cl)c(n1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F09 compound treatment 0.187 -0.0513 -0.54 0.276 -0.0476 -0.57 -0.7832 -0.9996 3041271 ChemDiv3_015607 COCc1nc2ccccc2n1C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F10 compound treatment 0.428 0.19 1.99 0.365 0.0414 0.5 1.7595 0.8569 3041273 ChemDiv3_015608 Cn1c(SCc2nc(no2)c3cccs3)nnc1c4ccncc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F11 compound treatment 0.192 -0.0463 -0.49 0.308 -0.0156 -0.19 -0.4754 -0.9133 3125128 ChemDiv3_015609 CCC(=O)NCCCc1nc2ccccc2n1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F12 compound treatment 0.428 0.19 1.99 0.5 0.176 2.11 2.9016 0.9996 3041275 ChemDiv3_015610 CCN(CC)C(=O)CCc1nc(no1)c2cccc(OC)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F13 compound treatment 0.302 0.0637 0.67 0.459 0.135 1.62 1.619 0.9235 3125129 ChemDiv3_015611 COC(=O)c1cc(c2cccc(OC)c2)c3c(=O)[nH]c(=O)n(C)c3n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F14 compound treatment 0.152 -0.0863 -0.91 0.228 -0.0956 -1.14 -1.4492 -0.9934 3125130 ChemDiv3_015612 COCCN1CCn2c(C1)nc3cc(Nc4nnc(C)c5ccccc45)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F15 compound treatment 0.262 0.0237 0.25 0.425 0.101 1.21 1.0343 0.8348 3041277 ChemDiv3_015613 CCOC(=O)c1c(C)[nH]c(NC(=O)Nc2nnc(CC)s2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F16 compound treatment 0.484 0.246 2.58 0.569 0.245 2.94 3.9013 0.9979 3125131 ChemDiv3_015614 C(N1CCCc2ccccc12)c3nnc(o3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F17 compound treatment 0.263 0.0247 0.26 0.429 0.105 1.26 1.0756 0.8351 3041279 ChemDiv3_015615 CCCCN(Cc1cc2cc(OC)ccc2nc1O)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F18 compound treatment 0.177 -0.0613 -0.64 0.257 -0.0666 -0.8 -1.0182 -0.9944 1604125 ChemDiv3_015616 OC(c1ccccc1)c2ccc3n4CCNC5CCCc(c54)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F19 compound treatment 0.273 0.0347 0.36 0.384 0.0604 0.72 0.7691 0.9498 3041281 ChemDiv3_015617 COC(=O)Cc1c(C)[nH]c2ncnn2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F20 compound treatment 0.251 0.0127 0.13 0.344 0.0204 0.24 0.2674 0.9595 3125132 ChemDiv3_015618 CCN(CC)CCNC1=NCCn2c1cc3cc(OC)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F21 compound treatment 0.288 0.0497 0.52 0.435 0.111 1.33 1.312 0.9163 3041283 ChemDiv3_015619 O=S(=O)(N1CCC(CC1)N2CCCCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F22 compound treatment 0.25 0.0117 0.12 0.304 -0.0196 -0.23 -0.0785 -0.2967 3125133 ChemDiv3_015620 OC1C(Cc2ccccc2)N3CCC1c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F23 mock treatment 0.232 -0.00628 -0.07 0.38 0.0564 0.68 0.4308 0.635 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 F24 mock treatment 0.2 -0.0383 -0.4 0.287 -0.0366 -0.44 -0.5936 -0.9991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G01 compound treatment 0.209 -0.0293 -0.31 0.224 -0.0996 -1.19 -1.0598 -0.8614 3125134 ChemDiv3_015621 O=C(CCN1C(=O)c2ccccc2Sc3ncccc13)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G02 compound treatment 1.12 0.882 9.26 1.147 0.823 9.85 13.5145 0.9995 3041285 ChemDiv3_015622 CCOC(=O)Cn1c(cc2ccccc12)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G03 compound treatment 0.207 -0.0313 -0.33 0.344 0.0204 0.24 -0.0594 -0.1451 3125135 ChemDiv3_015623 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c3nccn13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G04 compound treatment 0.217 -0.0213 -0.22 0.361 0.0374 0.45 0.1587 0.317 3041287 ChemDiv3_015624 O=S(=O)(N1CCOCC1)c2ccc(Nc3nc4ccccc4n5nnnc35)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G05 compound treatment 0.275 0.0367 0.39 0.385 0.0614 0.74 0.7925 0.9547 3125136 ChemDiv3_015625 COc1ccccc1NC(=O)Nc2nnc(s2)N3CC(C)CC(C)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G06 compound treatment 0.478 0.24 2.52 0.644 0.32 3.83 4.4912 0.9792 3125249 ChemDiv3_015626 CCc1ccccc1NC(=O)C2CCCN(C2)c3nnc(s3)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G07 compound treatment 0.878 0.64 6.72 0.984 0.66 7.9 10.3383 0.9967 3041344 ChemDiv3_015627 COC(=O)c1cc2sccc2n1C(C)C(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G08 compound treatment 0.316 0.0777 0.82 0.46 0.136 1.63 1.7315 0.9487 3041346 ChemDiv3_015628 Cc1cc(NC(=O)c2ccc3nc(sc3c2)N4CCOCC4)ccc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G09 compound treatment 0.093 -0.145 -1.53 0.121 -0.203 -2.42 -2.7926 -0.9751 3041347 ChemDiv3_015629 C(NCc1c[nH]nc1c2ccccc2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G10 compound treatment 0.233 -0.00528 -0.06 0.353 0.0294 0.35 0.2098 0.5885 3041349 ChemDiv3_015630 O=C(CCCN1C(=O)CSc2ncccc12)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G11 compound treatment 0.261 0.0227 0.24 0.37 0.0464 0.56 0.5616 0.9288 3041351 ChemDiv3_015631 CCc1ccc(NC(=O)N2CCc3cc(ccc23)S(=O)(=O)N4CCC(C)CC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G12 compound treatment 0.116 -0.122 -1.28 0.164 -0.16 -1.91 -2.258 -0.9814 3041352 ChemDiv3_015632 CN(C(=O)Cn1c(SCc2ccccc2F)nc3ccncc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G13 compound treatment 0.657 0.419 4.4 0.775 0.451 5.4 6.9288 0.9948 3125250 ChemDiv3_015633 CCOc1ccccc1CNC(=O)c2ccc3SCCN(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G14 compound treatment 0.121 -0.117 -1.23 0.144 -0.18 -2.15 -2.3901 -0.9651 3125251 ChemDiv3_015634 COc1cccc(Cn2c(SCc3ccc(cc3)C(=O)NCc4ccccn4)nc5ccncc25)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G15 compound treatment 0.316 0.0777 0.82 0.447 0.123 1.48 1.6215 0.9609 3041354 ChemDiv3_015635 COC(=O)c1cnc2sc3ccccc3n2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G16 compound treatment 0.268 0.0297 0.31 0.414 0.0904 1.08 0.9858 0.8754 3041355 ChemDiv3_015636 Cc1cc(=O)n2nc(sc2n1)N3CCCC3C(=O)Nc4cccc(F)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G17 compound treatment 0.15 -0.0883 -0.93 0.238 -0.0856 -1.02 -1.3795 -0.9988 3125252 ChemDiv3_015637 OC(=O)c1ccc(Cn2c(SCc3ccccc3F)nc4ccncc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G18 compound treatment 0.261 0.0227 0.24 0.382 0.0584 0.7 0.6631 0.8976 3125253 ChemDiv3_015638 Cc1n(Cc2ccc(Cl)cc2)c(C)c3c(=O)n(CC(=O)N4CCc5ccccc45)ncc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G19 compound treatment 0.28 0.0417 0.44 0.385 0.0614 0.74 0.8296 0.9694 3041357 ChemDiv3_015639 CC1(C)Oc2ccc(OCC(=O)O)cc2C=C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G20 compound treatment 0.322 0.0837 0.88 0.462 0.138 1.66 1.7929 0.9561 3125254 ChemDiv3_015640 Cc1nc2nc(CNC(=O)OC(C)(C)C)nn2c(C)c1CCC(=O)Nc3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G21 compound treatment 0.681 0.443 4.65 0.823 0.499 5.98 7.5132 0.9923 3041359 ChemDiv3_015641 CCOC(=O)c1cc(C)n(c1C)c2ccc(C)c(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G22 compound treatment 0.606 0.368 3.86 0.662 0.338 4.05 5.5941 0.9997 3041361 ChemDiv3_015642 CCN(Cc1ccccc1)C(=O)c2cc3CSc4cc(Cl)ccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G23 mock treatment 0.19 -0.0483 -0.51 0.364 0.0404 0.48 -0.0165 -0.0235 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 G24 mock treatment 0.241 0.00272 0.03 0.331 0.00744 0.09 0.0831 0.8893 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H01 compound treatment 0.201 -0.0373 -0.39 0.262 -0.0616 -0.74 -0.7977 -0.9563 3125255 ChemDiv3_015643 COc1cccc(c1)N(Cc2ccc(C)cc2)C3=NC4CS(=O)(=O)CC4S3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H02 compound treatment 0.27 0.0317 0.33 0.391 0.0674 0.81 0.8061 0.9234 3125256 ChemDiv3_015644 COc1ccc(NC(=O)N2CCc3cc(OC)c(OC)cc3C2c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H03 compound treatment 0.337 0.0987 1.04 0.399 0.0754 0.9 1.3713 0.9976 3041363 ChemDiv3_015645 CCN1Cc2cccc(CNc3ccc(CC)cc3)c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H04 compound treatment 0.151 -0.0873 -0.92 0.2 -0.124 -1.48 -1.6936 -0.9736 3125257 ChemDiv3_015646 O=C(CCC1CCCC1)Nc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H05 compound treatment 0.252 0.0137 0.14 0.302 -0.0216 -0.26 -0.0805 -0.2726 3041365 ChemDiv3_015647 CCc1ccccc1N2CC(CC2=O)c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H06 compound treatment 0.15 -0.0883 -0.93 0.163 -0.161 -1.92 -2.014 -0.9442 3125258 ChemDiv3_015648 CC(C)c1ccc(CN(C2CCS(=O)(=O)C2)C(=O)c3nc(ncc3Cl)S(=O)(=O)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H07 compound treatment 0.053 -0.185 -1.95 0.049 -0.275 -3.28 -3.6988 -0.9688 3041367 ChemDiv3_015649 CSc1nc2ccccc2n1Cc3ccc(cc3)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H08 compound treatment 0.227 -0.0113 -0.12 0.337 0.0134 0.16 0.0299 0.1497 3125259 ChemDiv3_015650 CCCSc1ncc(Cl)c(n1)C(=O)Nc2nc(C)c(s2)C(=O)OCC(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H09 compound treatment 0.111 -0.127 -1.34 0.131 -0.193 -2.3 -2.5744 -0.9665 3041369 ChemDiv3_015651 CCCCn1c(COC)nc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H10 compound treatment 0.966 0.728 7.64 0.978 0.654 7.83 10.941 0.9999 3125260 ChemDiv3_015652 Cc1nnc(SCc2nc(no2)c3ccc(Cl)cc3)n1c4ccc(C)c(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H11 compound treatment 0.141 -0.0973 -1.02 0.182 -0.142 -1.69 -1.9201 -0.9707 3041371 ChemDiv3_015653 Clc1ccc(cc1)C(=O)Cn2cnc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H12 compound treatment 0.274 0.0357 0.38 0.345 0.0214 0.26 0.4466 0.9828 3041410 ChemDiv3_015654 CNC(=O)CCc1nc(no1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H13 compound treatment 0.573 0.335 3.52 0.637 0.313 3.75 5.1375 0.9995 3041411 ChemDiv3_015655 Clc1ccc(cc1)c2ncnc3c(C#N)c4ccccn4c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H14 compound treatment 0.202 -0.0363 -0.38 0.3 -0.0236 -0.28 -0.4688 -0.989 3041413 ChemDiv3_015656 CC(=O)NCCc1nc2cc(NC(=O)C)ccc2n1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H15 compound treatment 0.263 0.0247 0.26 0.414 0.0904 1.08 0.9487 0.8526 3041414 ChemDiv3_015657 CCCNC(=O)Nc1[nH]c(C)c(C(=O)OCC)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H16 compound treatment 0.359 0.121 1.27 0.485 0.161 1.93 2.2623 0.9792 3041416 ChemDiv3_015658 O=c1oc2ccccc2n1Cc3nnc(o3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H17 compound treatment 0.274 0.0357 0.38 0.4 0.0764 0.91 0.9119 0.9226 3041417 ChemDiv3_015659 CCCCN(Cc1cc2cc(OC)ccc2nc1O)C(=O)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H18 compound treatment 0.128 -0.11 -1.16 0.161 -0.163 -1.94 -2.1943 -0.9693 3041419 ChemDiv3_015660 COc1ccc2n3CCN=C4N(C)CCc(c43)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H19 compound treatment 0.199 -0.0393 -0.41 0.303 -0.0206 -0.25 -0.4657 -0.9695 3041420 ChemDiv3_015661 O=C(Nc1ccc2n3CCN(Cc3nc2c1)c4ccccc4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H20 compound treatment 0.159 -0.0793 -0.83 0.308 -0.0156 -0.19 -0.7204 -0.8444 3041422 ChemDiv3_015662 COc1ccc2n3CCN4CCN=C4c3cc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H21 compound treatment 0.325 0.0867 0.91 0.417 0.0934 1.12 1.4345 0.9948 3125261 ChemDiv3_015663 Cc1[nH]c2ccc(CNC(=O)Nc3ccc(F)cc3F)cc2c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H22 compound treatment 0.103 -0.135 -1.42 0.128 -0.196 -2.34 -2.6592 -0.9714 3125262 ChemDiv3_015664 Clc1ccccc1OCC(=O)N(C2CN3CCC2CC3)c4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H23 mock treatment 0.246 0.00772 0.08 0.38 0.0564 0.68 0.5348 0.7864 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 H24 mock treatment 0.221 -0.0173 -0.18 0.277 -0.0466 -0.56 -0.5223 -0.8914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I01 compound treatment 0.145 -0.0933 -0.98 0.208 -0.116 -1.38 -1.6704 -0.9858 3041425 ChemDiv3_015665 COC(=O)c1cc2sccc2n1CC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I02 compound treatment 0.646 0.408 4.28 0.668 0.344 4.12 5.9419 0.9998 3125263 ChemDiv3_015666 COc1ccc(cc1)c2noc(n2)N(C)CC(=O)N3CCN(CC3)c4ccccc4OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I03 compound treatment 0.23 -0.00828 -0.09 0.336 0.0124 0.15 0.0437 0.2537 3041427 ChemDiv3_015667 Cc1nn(CCCC(=O)NC2CCCC2)c(=O)c3nccn13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I04 compound treatment 0.768 0.53 5.56 0.89 0.566 6.78 8.7261 0.9952 3125264 ChemDiv3_015668 C(CC1=CCCCC1)Nc2nc3ccccc3n4nnnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I05 compound treatment 0.248 0.00972 0.1 0.353 0.0294 0.35 0.3212 0.876 3125265 ChemDiv3_015669 COc1ccccc1NC(=O)Nc2nnc(s2)N3CCCCC3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I06 compound treatment 0.384 0.146 1.53 0.434 0.11 1.32 2.0165 0.9973 3041429 ChemDiv3_015670 O=C(NCCc1ccccc1)C2CCCN(C2)c3nnc(s3)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I07 compound treatment 1.06 0.822 8.63 1.103 0.779 9.33 12.6967 0.9993 3125266 ChemDiv3_015671 COC(=O)c1cc2sccc2n1C(C)C(=O)Nc3ccccc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I08 compound treatment 0.268 0.0297 0.31 0.37 0.0464 0.56 0.6136 0.9628 3041432 ChemDiv3_015672 O=C(N1CCCC1)c2ccc3nc(sc3c2)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I09 compound treatment 0.131 -0.107 -1.13 0.157 -0.167 -1.99 -2.2059 -0.9636 3125267 ChemDiv3_015673 Fc1cccc(CNCc2c[nH]nc2c3ccc(Br)cc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I10 compound treatment 0.25 0.0117 0.12 0.344 0.0204 0.24 0.2599 0.9495 3041434 ChemDiv3_015674 O=C(CCCN1C(=O)CSc2ncccc12)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I11 compound treatment 0.248 0.00972 0.1 0.29 -0.0336 -0.4 -0.2118 -0.5111 3125268 ChemDiv3_015675 COc1ccccc1c2n[nH]cc2CNCc3ccccc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I12 compound treatment 0.101 -0.137 -1.44 0.11 -0.214 -2.56 -2.8263 -0.9633 3125269 ChemDiv3_015676 CCC1CCCCN1C(=O)Cn2c(SCc3cccc(Cl)c3)nc4ccncc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I13 compound treatment 0.248 0.00972 0.1 0.343 0.0194 0.23 0.2366 0.9317 3041471 ChemDiv3_015677 COc1ccc(cc1)c2cn3nc(sc3n2)N4CCC(CC4)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I14 compound treatment 0.102 -0.136 -1.43 0.114 -0.21 -2.51 -2.785 -0.9647 3041473 ChemDiv3_015678 CN(Cc1ccccc1)C(=O)c2ccc(CSc3nc4ccncc4n3Cc5ccccc5)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I15 compound treatment 0.248 0.00972 0.1 0.369 0.0454 0.54 0.4566 0.8254 3041474 ChemDiv3_015679 Cn1c(SCc2ccc(F)cc2)nc3ccc(cc13)C(=O)N4CCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I16 compound treatment 0.278 0.0397 0.42 0.435 0.111 1.33 1.2377 0.886 3041475 ChemDiv3_015680 COc1ccccc1CNC(=O)C2CCCN2c3nn4c(=O)cc(C)nc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I17 compound treatment 0.087 -0.151 -1.59 0.095 -0.229 -2.73 -3.0572 -0.9666 3041477 ChemDiv3_015681 CC1=C(c2ccc(C)cc2)S(=O)(=O)N(CC(=O)N3CCN(CC3)c4ccccn4)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I18 compound treatment 0.309 0.0707 0.74 0.459 0.135 1.62 1.671 0.9374 3125270 ChemDiv3_015682 Cc1n(Cc2ccc(Cl)cc2)c(C)c3c(=O)n(CC(=O)NC4CCCc5ccccc45)ncc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I19 compound treatment 1.304 1.07 11.19 1.301 0.977 11.69 16.1838 0.9998 3041478 ChemDiv3_015683 CCOC(=O)C1=CNc2ccccc2S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I20 compound treatment 0.246 0.00772 0.08 0.38 0.0564 0.68 0.5348 0.7864 3041480 ChemDiv3_015684 COc1ccc(OC)c(CNC(=O)CN2Cc3ccccc3C2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I21 compound treatment 0.631 0.393 4.12 0.757 0.433 5.19 6.5835 0.9936 3125271 ChemDiv3_015685 COC(=O)c1ccc(c2ccco2)n1CC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I22 compound treatment 0.251 0.0127 0.13 0.363 0.0394 0.47 0.4281 0.873 3125272 ChemDiv3_015686 CC1CCCCN1CCCNC(=O)c2cc3CSc4cc(Cl)ccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I23 mock treatment 0.194 -0.0443 -0.47 0.293 -0.0306 -0.37 -0.5874 -0.9929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 I24 mock treatment 0.238 -2.81E-4 0.0 0.301 -0.0226 -0.27 -0.193 -0.7148 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J01 compound treatment 0.254 0.0157 0.17 0.312 -0.0116 -0.14 0.0189 0.0878 3041482 ChemDiv3_015687 Cc1cccc(NC(=O)CN(C2=NC3CS(=O)(=O)CC3S2)c4ccccc4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J02 compound treatment 0.323 0.0847 0.89 0.413 0.0894 1.07 1.3858 0.9958 3125273 ChemDiv3_015688 O=C(NCCSc1nnnn1c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J03 compound treatment 0.412 0.174 1.82 0.506 0.182 2.18 2.8336 0.996 3041484 ChemDiv3_015689 CCN1Cc2cccc(CNc3cc(C)cc(C)c3)c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J04 compound treatment 0.125 -0.113 -1.19 0.153 -0.171 -2.04 -2.2843 -0.967 3125274 ChemDiv3_015690 O=C(CC1CCCC1)Nc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J05 compound treatment 0.197 -0.0413 -0.43 0.286 -0.0376 -0.45 -0.6244 -0.9998 1201997 ChemDiv3_015691 O=C(NCCc1nc2ccccc2[nH]1)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J06 compound treatment 0.288 0.0497 0.52 0.399 0.0754 0.9 1.0074 0.9662 3125275 ChemDiv3_015692 CSc1ncc(Cl)c(n1)C(=O)Nc2cc(C)ccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J07 compound treatment 0.164 -0.0743 -0.78 0.205 -0.119 -1.42 -1.5547 -0.9603 3125516 ChemDiv3_015693 COc1ccc(Cc2nc3ccccc3n2Cc4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J08 compound treatment 0.292 0.0537 0.56 0.307 -0.0166 -0.2 0.2588 0.4328 3041488 ChemDiv3_015694 CCc1c(C)nc(SCC(=O)N2CCN(CC2)c3ccccc3)[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J09 compound treatment 0.144 -0.0943 -0.99 0.159 -0.165 -1.97 -2.0924 -0.9494 3125388 ChemDiv3_015695 CCC(C)Cn1c(Cc2ccc(OC)cc2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J10 compound treatment 0.484 0.246 2.58 0.505 0.181 2.17 3.3598 0.9963 3125389 ChemDiv3_015696 COc1ccc(cc1)c2noc(CSc3nnc(C)n3c4ccc(Cl)cc4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J11 compound treatment 0.077 -0.161 -1.69 0.094 -0.23 -2.75 -3.1399 -0.973 1473846 ChemDiv3_015697 Cn1c(nc2ccccc12)C(O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J12 compound treatment 0.374 0.136 1.43 0.441 0.117 1.41 2.0015 1.0 3125390 ChemDiv3_015698 CC(C)NC(=O)CCc1nc(no1)c2ccc(cc2)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J13 compound treatment 0.442 0.204 2.14 0.554 0.23 2.76 3.4625 0.9921 3041491 ChemDiv3_015699 Cc1cccc(NC(=O)Cc2coc3ccc(C)cc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J14 compound treatment 0.192 -0.0463 -0.49 0.257 -0.0666 -0.8 -0.9068 -0.972 3125391 ChemDiv3_015700 CC(=O)Nc1ccc2n(C)c(CN3CCCC3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J15 compound treatment 0.455 0.217 2.28 0.563 0.239 2.86 3.6351 0.9935 3041494 ChemDiv3_015701 COC(=O)CCc1sc(NC2CCCCC2)nc1c3ccc(OC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J16 compound treatment 0.679 0.441 4.63 0.737 0.413 4.95 6.7707 0.9994 3125392 ChemDiv3_015702 Clc1ccccc1OCc2nnc(o2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J17 compound treatment 0.276 0.0377 0.4 0.365 0.0414 0.5 0.6307 0.9938 3041506 ChemDiv3_015703 CCOC(=O)c1c[nH]c2nc(NCc3ccc(Cl)cc3)nn2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J18 compound treatment 0.079 -0.159 -1.67 0.114 -0.21 -2.51 -2.9558 -0.9807 3041508 ChemDiv3_015704 COc1ccc2n3CCN(C4CCCCC4)C5=NCCc(c53)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J19 compound treatment 0.224 -0.0143 -0.15 0.284 -0.0396 -0.47 -0.4408 -0.8877 3041510 ChemDiv3_015705 Cc1cccc(OCC(=O)Nc2ccc3n4CCN(Cc4nc3c2)c5ccccc5)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J20 compound treatment 0.239 7.19E-4 0.01 0.379 0.0554 0.66 0.4743 0.7151 1371853 ChemDiv3_015706 CN1CCN(CCOc2ccccc2OCc3cc(C)on3)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J21 compound treatment 0.24 0.00172 0.02 0.356 0.0324 0.39 0.2872 0.7392 3041755 ChemDiv3_015707 Cc1ccc(NC(=O)N2CCN(CC2)c3cnccn3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J22 compound treatment 0.092 -0.146 -1.54 0.108 -0.216 -2.58 -2.91 -0.9694 3041758 ChemDiv3_015708 COc1ccc(CC2CC3CCN2CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J23 mock treatment 0.24 0.00172 0.02 0.363 0.0394 0.47 0.3464 0.7336 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 J24 mock treatment 0.221 -0.0173 -0.18 0.321 -0.00256 -0.03 -0.15 -0.815 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K01 compound treatment 0.196 -0.0423 -0.44 0.265 -0.0586 -0.7 -0.8094 -0.9758 3125393 ChemDiv3_015709 COc1ccc(CNC(=O)c2c[nH]nc2c3ccc(OC)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K02 compound treatment 0.671 0.433 4.54 0.685 0.361 4.32 6.2714 0.9997 3042079 ChemDiv3_015710 Fc1ccc(NC(=O)c2cc3CSc4ccccc4-c3s2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K03 compound treatment 0.416 0.178 1.87 0.487 0.163 1.96 2.7025 0.9997 3125394 ChemDiv3_015711 COC(=O)c1c(NC(=O)C)c2c(C)c(C)sc2n1Cc3nc(oc3C)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K04 compound treatment 0.296 0.0577 0.61 0.364 0.0404 0.48 0.7708 0.9938 3042084 ChemDiv3_015712 O=C(NCc1ccccc1)C2CCN(CC2)c3nnc(s3)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K05 compound treatment 0.297 0.0587 0.62 0.367 0.0434 0.52 0.8036 0.9964 3125395 ChemDiv3_015713 CC1CCCCN1c2nnc(NC(=O)Nc3ccccc3C(F)(F)F)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K06 compound treatment 0.424 0.186 1.95 0.502 0.178 2.13 2.8888 0.999 3125396 ChemDiv3_015714 O=C(NC1CCCc2ccccc12)C3CCCN(C3)c4nnc(s4)n5cccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K07 compound treatment 0.295 0.0567 0.6 0.33 0.00644 0.08 0.4757 0.7919 3042095 ChemDiv3_015715 CCOC(=O)C1=C(C)NC(CS1)C(=O)NCc2cccc(OC)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K08 compound treatment 0.22 -0.0183 -0.19 0.297 -0.0266 -0.32 -0.3605 -0.9709 3125397 ChemDiv3_015716 CC1CCN(CC1)C(=O)CN2C(=O)CSc3ncccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K09 compound treatment 0.372 0.134 1.4 0.449 0.125 1.5 2.0543 0.9995 3125398 ChemDiv3_015717 Cc1ccc(C)c(NCc2c[nH]nc2c3ccc(Br)cc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K10 compound treatment 0.243 0.00472 0.05 0.346 0.0224 0.27 0.2249 0.8237 3042162 ChemDiv3_015718 O=C(CCCN1C(=O)CSc2ncccc12)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K11 compound treatment 0.326 0.0877 0.92 0.418 0.0944 1.13 1.4504 0.9949 3125399 ChemDiv3_015719 CC1CCN(CC1)S(=O)(=O)c2ccc3n(CC(=O)NCc4ccccc4)ccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K12 compound treatment 0.194 -0.0443 -0.47 0.259 -0.0646 -0.77 -0.8751 -0.9705 3042169 ChemDiv3_015720 Cc1oc(nc1CSc2nc3ccncc3[nH]2)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K13 compound treatment 0.131 -0.107 -1.13 0.168 -0.156 -1.86 -2.1128 -0.9711 3125400 ChemDiv3_015721 Cc1oc(nc1COc2ccccc2)c3ccc(cc3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K14 compound treatment 0.1 -0.138 -1.45 0.119 -0.205 -2.45 -2.7576 -0.9689 3125401 ChemDiv3_015722 CC(C)CCNC(=O)c1ccc(CSc2nc3ccncc3n2Cc4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K15 compound treatment 0.434 0.196 2.06 0.492 0.168 2.02 2.8785 1.0 3042177 ChemDiv3_015723 Oc1ccc2nc(sc2c1)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K16 compound treatment 0.231 -0.00728 -0.08 0.355 0.0314 0.38 0.2119 0.552 3125402 ChemDiv3_015724 CC(Nc1nn2c(=O)cc(C)nc2s1)C(=O)NCCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K17 compound treatment 0.176 -0.0623 -0.65 0.265 -0.0586 -0.7 -0.958 -0.9994 3042182 ChemDiv3_015725 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)NC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K18 compound treatment 0.155 -0.0833 -0.87 0.168 -0.156 -1.86 -1.9346 -0.9407 3125403 ChemDiv3_015726 Cc1ccc(cc1)C2C(NC(=O)c3ccccc3)C(=O)N2c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K19 compound treatment 0.247 0.00872 0.09 0.396 0.0724 0.87 0.6776 0.7775 3042246 ChemDiv3_015727 CC(C)NC(=O)CN1C(=O)c2cccnc2Oc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K20 compound treatment 0.582 0.344 3.61 0.722 0.398 4.77 5.9235 0.9906 3125404 ChemDiv3_015728 O=C(NCC1(CCCC1)c2ccccc2)c3cc4CS(=O)(=O)c5ccccc5-c4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K21 compound treatment 0.47 0.232 2.43 0.611 0.287 3.44 4.1526 0.9857 3042251 ChemDiv3_015729 CCOc1ccccc1CNC(=O)Cn2c(C)c3cnn(c4ccccc4)c(=O)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K22 compound treatment 0.152 -0.0863 -0.91 0.238 -0.0856 -1.02 -1.3646 -0.9982 3125405 ChemDiv3_015730 CC1CCCCN1C(=O)CCS(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K23 mock treatment 0.216 -0.0223 -0.23 0.235 -0.0886 -1.06 -0.9147 -0.843 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 K24 mock treatment 0.224 -0.0143 -0.15 0.328 0.00444 0.05 -0.0685 -0.4306 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L01 compound treatment 0.243 0.00472 0.05 0.287 -0.0366 -0.44 -0.2743 -0.623 3042257 ChemDiv3_015731 CCc1ccc(NC(=O)CN(C2=NC3CS(=O)(=O)CC3S2)c4ccc(CC)cc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L02 compound treatment 0.176 -0.0623 -0.65 0.198 -0.126 -1.5 -1.5248 -0.9306 1915809 ChemDiv3_015732 CC(=O)NCCSc1nnnn1c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L03 compound treatment 0.238 -2.81E-4 0.0 0.336 0.0124 0.15 0.1031 0.6929 3125406 ChemDiv3_015733 Cc1nn(C)c2nc(C)c(CCC(=O)NCCCc3ccccc3)c(C)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L04 compound treatment 0.108 -0.13 -1.37 0.12 -0.204 -2.44 -2.6897 -0.9628 3042262 ChemDiv3_015734 CCCCC(=O)Nc1noc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L05 compound treatment 0.076 -0.162 -1.7 0.093 -0.231 -2.76 -3.1558 -0.9732 3125407 ChemDiv3_015735 Cn1c(CCCNC(=O)C2CCCCC2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L06 compound treatment 0.701 0.463 4.86 0.785 0.461 5.52 7.3402 0.998 3125408 ChemDiv3_015736 CSc1ncc(Cl)c(n1)C(=O)N2CCN(CC2)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L07 compound treatment 0.086 -0.152 -1.6 0.116 -0.208 -2.48 -2.8869 -0.9774 1604251 ChemDiv3_015737 CC(C)Cc1nc2ccccc2n1CC(=O)N(C(C)C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L08 compound treatment 0.101 -0.137 -1.44 0.199 -0.125 -1.49 -2.0733 -0.9999 3125409 ChemDiv3_015738 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5ccccn5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L09 compound treatment 0.079 -0.159 -1.67 0.092 -0.232 -2.77 -3.142 -0.9708 3042330 ChemDiv3_015739 CCC(C)Cn1c(CC(C)(C)C)nc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L10 compound treatment 0.425 0.187 1.96 0.433 0.109 1.31 2.3125 0.9807 3125410 ChemDiv3_015740 COc1ccc(cc1OC)c2noc(CSc3nnc(CCc4ccccc4)n3C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L11 compound treatment 0.269 0.0307 0.32 0.346 0.0224 0.27 0.418 0.9958 3042336 ChemDiv3_015741 O=C(Nc1ccccc1)N2CCC(CC2)n3c(=O)[nH]c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L12 compound treatment 0.251 0.0127 0.13 0.329 0.00544 0.07 0.1405 0.9453 3125411 ChemDiv3_015742 O=C(CCc1nc(no1)c2ccccc2)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L13 compound treatment 0.32 0.0817 0.86 0.386 0.0624 0.75 1.1351 0.9976 3042339 ChemDiv3_015743 Cc1ccc2occ(CC(=O)Nc3ccc(F)cc3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L14 compound treatment 0.25 0.0117 0.12 0.381 0.0574 0.69 0.573 0.8207 3125412 ChemDiv3_015744 Oc1ccccc1c2n[nH]c3C(=O)N(CCc4ccccc4)C(c23)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L15 compound treatment 0.857 0.619 6.5 0.905 0.581 6.96 9.514 0.9994 3042343 ChemDiv3_015745 COc1cccc(c1)c2noc(n2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L16 compound treatment 0.634 0.396 4.16 0.714 0.39 4.67 6.242 0.9983 3125413 ChemDiv3_015746 Cc1ccccc1OCc2nnc(o2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L17 compound treatment 0.195 -0.0433 -0.45 0.337 0.0134 0.16 -0.2077 -0.4309 3041220 ChemDiv3_015747 Cc1[nH]c2nc(NCc3c(F)cccc3Cl)nn2c(=O)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L18 compound treatment 0.357 0.119 1.25 0.423 0.0994 1.19 1.7229 0.9997 1356992 ChemDiv3_015748 C1CCC(CC1)c2ccc3n4CCCNC5CCCc(c54)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L19 compound treatment 0.252 0.0137 0.14 0.34 0.0164 0.2 0.2409 0.9883 3125414 ChemDiv3_015749 COCCN1CCn2c(C1)nc3cc(NC(=O)C)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L20 compound treatment 0.212 -0.0263 -0.28 0.243 -0.0806 -0.96 -0.8767 -0.8744 1724187 ChemDiv3_015750 OC(Cc1ccccc1)(C2CN3CCC2CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L21 compound treatment 0.309 0.0707 0.74 0.452 0.128 1.54 1.6118 0.9444 1522123 ChemDiv3_015751 Fc1ccc(cc1)C(N2CCN(CC2)C(=O)NCc3ccccc3)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L22 compound treatment 0.075 -0.163 -1.71 0.101 -0.223 -2.66 -3.0955 -0.9773 3041230 ChemDiv3_015752 Oc1ccc(CC2CC3CCN2CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L23 mock treatment 0.247 0.00872 0.09 0.296 -0.0276 -0.33 -0.1684 -0.4921 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 L24 mock treatment 0.221 -0.0173 -0.18 0.277 -0.0466 -0.56 -0.5223 -0.8914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M01 compound treatment 0.24 0.00172 0.02 0.335 0.0114 0.14 0.1095 0.7935 3125517 ChemDiv3_015753 COc1ccc(cc1)c2n[nH]cc2C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M02 compound treatment 0.118 -0.12 -1.26 0.127 -0.197 -2.35 -2.5562 -0.9575 3125518 ChemDiv3_015754 CCN1CCCC1CNC(=O)c2cc3CSc4ccccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M03 compound treatment 0.12 -0.118 -1.24 0.134 -0.19 -2.27 -2.4821 -0.9599 3125519 ChemDiv3_015755 CC1(Cc2ccccc2C(=O)N1Cc3ccco3)C(=O)NC4CCCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M04 compound treatment 0.374 0.136 1.43 0.47 0.146 1.75 2.2468 0.9948 3041308 ChemDiv3_015756 CCc1ccc(NC(=O)C2CCN(CC2)c3nnc(s3)n4cccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M05 compound treatment 0.265 0.0267 0.28 0.328 0.00444 0.05 0.236 0.8262 3125520 ChemDiv3_015757 COc1ccc(CNC(=O)c2ccc3nc(sc3c2)N4CCOCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M06 compound treatment 0.364 0.126 1.32 0.49 0.166 1.99 2.3417 0.9801 3125521 ChemDiv3_015758 CC(NC(=O)C1CCCN(C1)c2nnc(s2)n3cccc3)c4ccc5OCCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M07 compound treatment 0.25 0.0117 0.12 0.382 0.0584 0.7 0.5814 0.819 3041314 ChemDiv3_015759 CN(CC(=O)N1CCCC1)c2nnc(s2)N3CCCC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M08 compound treatment 0.246 0.00772 0.08 0.28 -0.0436 -0.52 -0.3112 -0.59 3041316 ChemDiv3_015760 O=C(CN1C(=O)CSc2ncccc12)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M09 compound treatment 0.59 0.352 3.69 0.621 0.297 3.56 5.1284 0.9998 3125522 ChemDiv3_015761 CC1Cn2c(cc3c(Cl)ccc(O1)c23)C(=O)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M10 compound treatment 0.218 -0.0203 -0.21 0.268 -0.0556 -0.66 -0.6207 -0.8891 3125523 ChemDiv3_015762 CC(C)NC(=O)CCCN1C(=O)CSc2ncccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M11 compound treatment 0.089 -0.149 -1.57 0.305 -0.0186 -0.22 -1.2657 -0.7993 3041393 ChemDiv3_015763 Cc1oc(nc1CN2N=C(CCC2=O)N3CCOc4ccc(Cl)cc34)c5cccc(C)c5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M12 compound treatment 0.234 -0.00428 -0.04 0.323 -5.62E-4 -0.01 -0.0366 -0.804 3125524 ChemDiv3_015764 CCC(Sc1nc2ccncc2[nH]1)C(=O)Nc3ccccc3CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M13 compound treatment 0.24 0.00172 0.02 0.339 0.0154 0.18 0.1434 0.7725 3125525 ChemDiv3_015765 Cc1oc(nc1CSc2ccc(Cl)cc2)c3ccc(cc3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M14 compound treatment 0.221 -0.0173 -0.18 0.298 -0.0256 -0.31 -0.3446 -0.969 3041402 ChemDiv3_015766 CNC(=O)c1ccc(Cn2c(SCc3ccc(C)cc3)nc4ccncc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M15 compound treatment 0.289 0.0507 0.53 0.34 0.0164 0.2 0.5157 0.9082 3125526 ChemDiv3_015767 COc1ccc(cc1)C(=O)Cn2ccnc2C(=O)N3CCN(CC3)c4ccccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M16 compound treatment 0.218 -0.0203 -0.21 0.3 -0.0236 -0.28 -0.35 -0.9904 3041405 ChemDiv3_015768 CN(CC(=O)NCc1ccccc1)c2nn3c(=O)cc(C)nc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M17 compound treatment 0.256 0.0177 0.19 0.288 -0.0356 -0.43 -0.1693 -0.3645 3041454 ChemDiv3_015769 COC(=O)Cn1cc2CCc3oc(C(=O)N4CCCC4)c(C)c3-c2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M18 compound treatment 0.202 -0.0363 -0.38 0.337 0.0134 0.16 -0.1558 -0.3766 3125527 ChemDiv3_015770 O=c1[nH]nc(NCc2nc3cccnc3[nH]2)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M19 compound treatment 0.259 0.0207 0.22 0.378 0.0544 0.65 0.6144 0.8947 3041457 ChemDiv3_015771 O=C(CN1C(=O)c2cccnc2Oc3ccccc13)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M20 compound treatment 0.275 0.0367 0.39 0.422 0.0984 1.18 1.1055 0.892 3125528 ChemDiv3_015772 CCCN1CCN(CCCNC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M21 compound treatment 0.825 0.587 6.16 0.929 0.605 7.24 9.4794 0.9968 1066700 ChemDiv3_015773 CCOC(=O)c1cc2ccccc2n1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M22 compound treatment 0.348 0.11 1.15 0.415 0.0914 1.09 1.5884 0.9997 3125529 ChemDiv3_015774 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M23 mock treatment 0.231 -0.00728 -0.08 0.325 0.00144 0.02 -0.0419 -0.5347 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 M24 mock treatment 0.239 7.19E-4 0.01 0.297 -0.0266 -0.32 -0.2194 -0.6901 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N01 compound treatment 0.413 0.175 1.84 0.464 0.14 1.68 2.4857 0.999 3041466 ChemDiv3_015775 CCCN(CCC)C(=O)Cc1c(C)nc2c(c(C)nn2c1C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N02 compound treatment 0.283 0.0447 0.47 0.344 0.0204 0.24 0.505 0.9537 3125530 ChemDiv3_015776 CC(C)(C)C(=O)NCCSc1nnnn1c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N03 compound treatment 0.203 -0.0353 -0.37 0.245 -0.0786 -0.94 -0.9267 -0.9172 3042709 ChemDiv3_015777 O=c1n(CCCN2CCCC2)cnc3c4ccccc4[nH]c13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N04 compound treatment 0.124 -0.114 -1.2 0.128 -0.196 -2.34 -2.5032 -0.9519 3042710 ChemDiv3_015778 O=S(=O)(Cc1ccccc1)Nc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N05 compound treatment 0.212 -0.0263 -0.28 0.249 -0.0746 -0.89 -0.826 -0.8845 3042711 ChemDiv3_015779 Fc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N06 compound treatment 1.212 0.974 10.23 0.812 0.488 5.84 11.3636 0.9648 3042712 ChemDiv3_015780 CCSc1ncc(Cl)c(n1)C(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N07 compound treatment 0.174 -0.0643 -0.68 0.207 -0.117 -1.39 -1.4635 -0.9446 3042713 ChemDiv3_015781 CCc1nc2ccccc2n1CCCOc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N08 compound treatment 0.053 -0.185 -1.95 0.067 -0.257 -3.07 -3.5465 -0.9758 3042714 ChemDiv3_015782 C(c1nn2c(Cn3cnc4ccccc34)nnc2s1)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N09 compound treatment 0.069 -0.169 -1.78 0.087 -0.237 -2.83 -3.2585 -0.9749 3042715 ChemDiv3_015783 CC(C)CCn1c(CC(C)(C)C)nc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N10 compound treatment 0.256 0.0177 0.19 0.318 -0.00556 -0.07 0.0845 0.4277 3125531 ChemDiv3_015784 CCOc1ccc(cc1)C2SCC(=O)Nc3c2c(O)nn3C4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N11 compound treatment 0.332 0.0937 0.98 0.385 0.0614 0.74 1.2158 0.9897 1065280 ChemDiv3_015785 Oc1ccc(CN2CCCCC2)c3cccnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N12 compound treatment 0.575 0.337 3.54 0.633 0.309 3.7 5.1185 0.9997 3042716 ChemDiv3_015786 CC(C)NC(=O)CCc1nc(no1)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N13 compound treatment 0.358 0.12 1.26 0.453 0.129 1.55 1.9842 0.9947 3125532 ChemDiv3_015787 CCc1ccc2occ(CC(=O)Nc3ccc(Cl)cc3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N14 compound treatment 0.365 0.127 1.33 0.393 0.0694 0.83 1.5285 0.9743 3125533 ChemDiv3_015788 CSc1ncc(Cl)c(n1)C(=O)N(Cc2ccccc2)c3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N15 compound treatment 0.191 -0.0473 -0.5 0.281 -0.0426 -0.51 -0.7112 -0.9999 3042717 ChemDiv3_015789 COc1nc2c(C)cccc2cc1c3noc(n3)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N16 compound treatment 0.84 0.602 6.32 1.17 0.846 10.13 11.6297 0.9742 3125534 ChemDiv3_015790 C(Oc1ccc2ccccc2c1)c3nnc(o3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N17 compound treatment 0.246 0.00772 0.08 0.344 0.0204 0.24 0.2302 0.8937 3042718 ChemDiv3_015791 Cc1[nH]c2nc(COc3ccccc3)nn2c(=O)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N18 compound treatment 1.26 1.02 10.73 1.241 0.917 10.98 15.3495 0.9999 3125535 ChemDiv3_015792 C1Cc2c([nH]c3ccccc23)C4N(NC=C14)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N19 compound treatment 0.158 -0.0803 -0.84 0.256 -0.0676 -0.81 -1.1678 -0.9998 3042719 ChemDiv3_015793 CN(Cc1nc2ccccc2n1C)C(=O)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N20 compound treatment 0.212 -0.0263 -0.28 0.299 -0.0246 -0.29 -0.403 -0.9995 1201745 ChemDiv3_015794 OC(Cc1ccccc1)(Cc2ccccc2)C3CN4CCC3CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N21 compound treatment 0.506 0.268 2.81 0.587 0.263 3.15 4.2169 0.9984 3125536 ChemDiv3_015795 O=C(NCCSc1nnnn1c2ccccc2)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N22 compound treatment 0.2 -0.0383 -0.4 0.286 -0.0376 -0.45 -0.6021 -0.9985 1526524 ChemDiv3_015796 Clc1ccc(OCC(=O)NC2CN3CCC2CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N23 mock treatment 0.206 -0.0323 -0.34 0.298 -0.0256 -0.31 -0.456 -0.9987 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 N24 mock treatment 0.225 -0.0133 -0.14 0.275 -0.0486 -0.58 -0.5095 -0.8526 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O01 compound treatment 0.233 -0.00528 -0.06 0.283 -0.0406 -0.49 -0.3824 -0.7828 3125537 ChemDiv3_015797 COc1ccc(cc1)c2n[nH]cc2C(=O)NCCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O02 compound treatment 0.259 0.0207 0.22 0.289 -0.0346 -0.41 -0.1385 -0.2965 3042720 ChemDiv3_015798 C(CNc1nc2ccccc2n3nnnc13)CN4CCc5ccccc5C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O03 compound treatment 0.173 -0.0653 -0.69 0.223 -0.101 -1.2 -1.3356 -0.9644 3125538 ChemDiv3_015799 CCCN1C(=O)c2ccccc2CC1(C)C(=O)NC3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O04 compound treatment 0.202 -0.0363 -0.38 0.288 -0.0356 -0.43 -0.5703 -0.9985 3125539 ChemDiv3_015800 CC(C)CCNC(=O)C1CCN(CC1)c2nnc(s2)n3cccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O05 compound treatment 0.37 0.132 1.38 0.393 0.0694 0.83 1.5657 0.9702 3042721 ChemDiv3_015801 COC(=O)c1ccc2SCC(=O)N(CC(=O)N3CCOc4ccc(C)cc34)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O06 compound treatment 0.212 -0.0263 -0.28 0.285 -0.0386 -0.46 -0.5214 -0.9698 3125540 ChemDiv3_015802 CNC(=O)C1CCN(CC1)c2nnc(s2)n3c(C)ccc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O07 compound treatment 0.515 0.277 2.91 0.486 0.162 1.94 3.4293 0.9809 3125541 ChemDiv3_015803 COc1cccc(CNC(=O)c2cnn3c4CCCCCc4cnc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O08 compound treatment 0.179 -0.0593 -0.62 0.209 -0.115 -1.37 -1.4095 -0.9362 3042722 ChemDiv3_015804 CC1CCC(CC1)NC(=O)CN2C(=O)CSc3ncccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O09 compound treatment 0.87 0.632 6.63 0.995 0.671 8.03 10.3719 0.9955 3123629 ChemDiv3_015805 CC1Cn2c(cc3c(Cl)ccc(O1)c23)C(=O)N4CCc5ccccc5C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O10 compound treatment 0.188 -0.0503 -0.53 0.266 -0.0576 -0.69 -0.8604 -0.9914 3042723 ChemDiv3_015806 CCNC(=O)CN1C(=O)CSc2nc(C)cc(C)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O11 compound treatment 0.245 0.00672 0.07 0.241 -0.0826 -0.99 -0.6486 -0.6549 3123503 ChemDiv3_015807 O=C(NCCCN1CCOCC1)c2ccc(CN3C(=O)CCn4nccc34)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O12 compound treatment 0.097 -0.141 -1.48 0.115 -0.209 -2.5 -2.8137 -0.9692 3042724 ChemDiv3_015808 CCC(Sc1nc2ccncc2[nH]1)C(=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O13 compound treatment 0.157 -0.0813 -0.85 0.185 -0.139 -1.66 -1.7759 -0.9524 3123504 ChemDiv3_015809 Cc1oc(nc1CN2CCCCC2)c3ccc(cc3)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O14 compound treatment 0.167 -0.0713 -0.75 0.228 -0.0956 -1.14 -1.3378 -0.9789 3123505 ChemDiv3_015810 CNC(=O)c1ccc(Cn2c(SCc3ccc(F)cc3)nc4ccncc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O15 compound treatment 0.14 -0.0983 -1.03 0.189 -0.135 -1.61 -1.8683 -0.9769 3042725 ChemDiv3_015811 Cc1ccc(CSc2nc3ccncc3n2Cc4ccc(cc4)C(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O16 compound treatment 0.267 0.0287 0.3 0.343 0.0194 0.23 0.3777 0.9917 3123506 ChemDiv3_015812 CCN1CCN(CC1)C(=O)C(C)n2c(C)c3cnn(c4ccccc4)c(=O)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O17 compound treatment 0.449 0.211 2.21 0.092 -0.232 -2.77 -0.3941 -0.1112 3042726 ChemDiv3_015813 Cc1ccccc1Cn2cc(CCCC(=O)O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O18 compound treatment 0.22 -0.0183 -0.19 0.293 -0.0306 -0.37 -0.3943 -0.9548 3123507 ChemDiv3_015814 Cc1cc(C)n2nc(CNC(=O)Nc3ccccc3Cl)nc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O19 compound treatment 0.214 -0.0243 -0.26 0.268 -0.0556 -0.66 -0.6504 -0.9135 3042727 ChemDiv3_015815 Cc1nn(CC(=O)O)c(=O)c2cccn12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O20 compound treatment 0.477 0.239 2.51 0.519 0.195 2.34 3.4263 0.9994 3123508 ChemDiv3_015816 Cc1ccccc1NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O21 compound treatment 0.243 0.00472 0.05 0.349 0.0254 0.3 0.2502 0.8116 3123509 ChemDiv3_015817 CC1CN(C(=O)N2CCC(CC2)C(=O)O)c3cc(C)ccc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O22 compound treatment 0.219 -0.0193 -0.2 0.276 -0.0476 -0.57 -0.5456 -0.9032 3042728 ChemDiv3_015818 CN(C(=O)CCS(=O)(=O)c1ccc2n(C)c(=O)c(=O)n(C)c2c1)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O23 mock treatment 0.232 -0.00628 -0.07 0.281 -0.0426 -0.51 -0.4067 -0.7921 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 O24 mock treatment 0.259 0.0207 0.22 0.304 -0.0196 -0.23 -0.0116 -0.0364 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P01 compound treatment 0.25 0.0117 0.12 0.329 0.00544 0.07 0.133 0.9556 3123510 ChemDiv3_015819 Cc1nc2cc(nn2c(C)c1CC(=O)N3CCCC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P02 compound treatment 0.269 0.0307 0.32 0.267 -0.0566 -0.68 -0.2504 -0.334 3123511 ChemDiv3_015820 COc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)N3CCc4cc(OC)c(OC)cc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P03 compound treatment 0.217 -0.0213 -0.22 0.256 -0.0676 -0.81 -0.7296 -0.87 3042729 ChemDiv3_015821 CCCN(CCC)CCn1cnc2c3ccccc3[nH]c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P04 compound treatment 0.216 -0.0223 -0.23 0.238 -0.0856 -1.02 -0.8893 -0.8469 3123512 ChemDiv3_015822 O=C1CCCN1c2ccc(cc2)S(=O)(=O)Nc3noc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P05 compound treatment 0.23 -0.00828 -0.09 0.243 -0.0806 -0.96 -0.7431 -0.7678 3042730 ChemDiv3_015823 CCCCn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P06 compound treatment 1.32 1.08 11.36 1.322 0.998 11.95 16.4803 0.9997 3123513 ChemDiv3_015824 CCSc1ncc(Cl)c(n1)C(=O)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P07 compound treatment 0.119 -0.119 -1.25 0.126 -0.198 -2.36 -2.5573 -0.9559 3042731 ChemDiv3_015825 CC(C)c1nc2ccccc2n1CCCOc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P08 compound treatment 1.393 1.15 12.13 1.387 1.06 12.72 17.5724 0.9997 3123514 ChemDiv3_015826 COc1ccc(Cc2nn3c(nnc3s2)c4ccccc4Br)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P09 compound treatment 0.115 -0.123 -1.29 0.15 -0.174 -2.08 -2.3839 -0.9742 3042732 ChemDiv3_015827 CCCn1c(nc2ccccc12)c3ccccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P10 compound treatment 0.426 0.188 1.97 0.44 0.116 1.39 2.3792 0.9855 3123515 ChemDiv3_015828 Cc1cccc(c1)c2noc(CCC(=O)NC(C)(C)C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P11 compound treatment 0.373 0.135 1.41 0.346 0.0224 0.27 1.1903 0.8265 3123516 ChemDiv3_015829 Oc1ccc(CN2CCN(CC2)c3ccccc3)c4cccnc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P12 compound treatment 0.2 -0.0383 -0.4 0.235 -0.0886 -1.06 -1.0335 -0.912 3042733 ChemDiv3_015830 Cc1cc(C)c2c(O)nc(SCc3ccccc3C)nc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P13 compound treatment 0.116 -0.122 -1.28 0.14 -0.184 -2.2 -2.4611 -0.9673 1868220 ChemDiv3_015831 COc1ccc(CNC(=O)Cc2coc3cc(C)cc(C)c23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P14 compound treatment 0.217 -0.0213 -0.22 0.264 -0.0596 -0.71 -0.662 -0.8863 3042734 ChemDiv3_015832 O=C(Cc1ccccc1)n2cnc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P15 compound treatment 0.32 0.0817 0.86 0.341 0.0174 0.21 0.7544 0.8541 3123517 ChemDiv3_015833 CN(Cc1cc2cc(C)ccc2nc1O)C(=O)c3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P16 compound treatment 0.369 0.131 1.37 0.387 0.0634 0.76 1.5075 0.961 1151784 ChemDiv3_015834 CCOc1ccc(cc1)C2N(C(=O)Cc3cc(OC)c(OC)cc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P17 compound treatment 0.193 -0.0453 -0.48 0.218 -0.106 -1.26 -1.2294 -0.9109 3123518 ChemDiv3_015835 Fc1cccc(Cl)c1CNc2nc3[nH]c4CCCc4c(=O)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P18 compound treatment 0.107 -0.131 -1.38 0.121 -0.203 -2.42 -2.6887 -0.9643 1472490 ChemDiv3_015836 COc1ccc2n3CCN(C)c4nc(nc(c2c1)c43)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P19 compound treatment 0.203 -0.0353 -0.37 0.205 -0.119 -1.42 -1.2651 -0.8629 3042735 ChemDiv3_015837 CN(Cc1nc2ccccc2n1C)S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P20 compound treatment 0.188 -0.0503 -0.53 0.204 -0.12 -1.43 -1.3849 -0.9082 1490763 ChemDiv3_015838 CC(=O)OC1(Cc2ccccc2)CN3CCC1c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P21 compound treatment 0.151 -0.0873 -0.92 0.251 -0.0726 -0.87 -1.2621 -0.9996 3123519 ChemDiv3_015839 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nc3ccc(C)cc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P22 compound treatment 0.197 -0.0413 -0.43 0.216 -0.108 -1.29 -1.2166 -0.8959 3042736 ChemDiv3_015840 CCCCn1c2nc(cn2c3ccccc13)c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P23 mock treatment 0.207 -0.0313 -0.33 0.291 -0.0326 -0.39 -0.5078 -0.9964 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2045 P24 mock treatment 0.237 -0.00128 -0.01 0.296 -0.0276 -0.33 -0.2427 -0.7353 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A01 compound treatment 0.218 -0.0305 -0.32 0.238 0.00675 0.08 -0.1692 -0.5126 3123520 ChemDiv3_015841 Cc1ccc(cc1)c2noc(CN(C3CCCCC3)S(=O)(=O)c4ccccc4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A02 compound treatment 0.475 0.227 2.38 0.438 0.207 2.47 3.4315 0.9998 3042737 ChemDiv3_015842 COc1ccc(cc1OC)c2noc(CN(C3CCCCC3)C(=O)Nc4cccc(Cl)c4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A03 compound treatment 0.59 0.342 3.59 0.624 0.393 4.7 5.8591 0.9911 3123521 ChemDiv3_015843 Cc1ccc(cc1)c2noc(CNC(=O)C(c3ccccc3)c4ccccc4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A04 compound treatment 0.262 0.0135 0.14 0.249 0.0177 0.21 0.2507 0.9809 3042738 ChemDiv3_015844 Cc1ccc2cnn(CC(=O)NC3CCCCC3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A05 compound treatment 0.557 0.309 3.24 0.572 0.341 4.08 5.1741 0.9935 3123522 ChemDiv3_015845 CN(CC(=O)NCc1nc(no1)c2cccc(C)c2)S(=O)(=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A06 compound treatment 0.172 -0.0765 -0.8 0.182 -0.0493 -0.59 -0.9846 -0.9884 3042739 ChemDiv3_015846 CN(C)CCNC(=O)Cn1ncc2c(Cl)cccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A07 compound treatment 0.183 -0.0655 -0.69 0.174 -0.0573 -0.68 -0.9705 -1.0 3123523 ChemDiv3_015847 CC(=O)N1CCN(CC1)c2ncnc3[nH]cnc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A08 compound treatment 0.35 0.102 1.07 0.344 0.113 1.35 1.7079 0.9932 3123524 ChemDiv3_015848 Cc1ccc2n(ncc2c1)C(=O)CCCC(=O)N3CCN(CC3)c4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A09 compound treatment 0.352 0.104 1.09 0.307 0.0757 0.91 1.4097 0.9959 3042740 ChemDiv3_015849 Cc1cccc(OCCn2c(CNC(=O)c3ccccc3)nc4ccccc24)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A10 compound treatment 0.293 0.0445 0.47 0.251 0.0198 0.24 0.4978 0.95 3123525 ChemDiv3_015850 Clc1cccc(NC(=O)n2ncc3cc(Cl)ccc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A11 compound treatment 0.24 -0.00847 -0.09 0.232 7.5E-4 0.01 -0.0565 -0.6326 3123526 ChemDiv3_015851 CCOc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A12 compound treatment 0.293 0.0445 0.47 0.267 0.0357 0.43 0.6332 0.999 3042741 ChemDiv3_015852 CN1C(=O)c2ccccc2Sc3ccc(NC(=O)N4CCCC4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A13 compound treatment 0.425 0.177 1.85 0.394 0.163 1.95 2.6879 0.9997 3123527 ChemDiv3_015853 O=C(CCCc1nc(no1)c2ccccc2)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A14 compound treatment 0.261 0.0125 0.13 0.263 0.0318 0.38 0.3617 0.8996 3123528 ChemDiv3_015854 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)NC4CCCC4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A15 compound treatment 0.254 0.00553 0.06 0.185 -0.0462 -0.55 -0.3502 -0.6294 3042742 ChemDiv3_015855 Cc1cc(Nc2ccccc2)n3cnnc3n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A16 compound treatment 0.402 0.154 1.61 0.369 0.138 1.65 2.3056 0.9999 3123630 ChemDiv3_015856 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A17 compound treatment 0.284 0.0355 0.37 0.241 0.00975 0.12 0.3464 0.8859 3042900 ChemDiv3_015857 C(Nc1cc(nc2nncn12)c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A18 compound treatment 0.603 0.355 3.72 0.561 0.33 3.95 5.4227 0.9996 3042957 ChemDiv3_015858 CC1CN(C(=O)CCC(=O)NC2CCCC(C)C2C)c3cc(Cl)ccc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A19 compound treatment 0.209 -0.0395 -0.41 0.183 -0.0483 -0.58 -0.7013 -0.9868 3042958 ChemDiv3_015859 Cn1c(nc2ccccc12)C3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A20 compound treatment 0.32 0.0715 0.75 0.265 0.0338 0.4 0.8168 0.9576 3042959 ChemDiv3_015860 O=C(CCC(=O)N1CCOc2ccccc12)NCc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A21 compound treatment 0.323 0.0745 0.78 0.338 0.107 1.28 1.4566 0.9724 3042961 ChemDiv3_015861 Cc1cccc(NC(=O)NCc2nc(no2)c3cccc(C)c3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A22 compound treatment 0.278 0.0295 0.31 0.258 0.0267 0.32 0.4456 0.9999 3042963 ChemDiv3_015862 CN(CC(=O)NCc1ccccc1)c2nnc(s2)N3CCCC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A23 mock treatment 0.289 0.0405 0.43 0.237 0.00575 0.07 0.3497 0.8109 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 A24 mock treatment 0.301 0.0525 0.55 0.337 0.106 1.27 1.2848 0.9308 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B01 compound treatment 0.355 0.107 1.12 0.329 0.0978 1.17 1.6181 0.9998 3042964 ChemDiv3_015863 CN(C(=O)C1=CC(=NS(=O)(=O)N1C)c2ccc(C)cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B02 compound treatment 0.396 0.148 1.55 0.427 0.196 2.34 2.7517 0.9799 3042965 ChemDiv3_015864 CC(CCc1ccccc1)NC(=O)Cc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B03 compound treatment 0.474 0.226 2.37 0.478 0.247 2.95 3.7624 0.994 3123631 ChemDiv3_015865 CCc1ccccc1NC(=O)C2=CC(=NS(=O)(=O)N2C)c3cccc(OC)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B04 compound treatment 0.428 0.18 1.89 0.349 0.118 1.41 2.3295 0.9897 3042967 ChemDiv3_015866 Cc1ccc2onc(CC(=O)NC3CCCCC3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B05 compound treatment 0.591 0.343 3.6 0.55 0.319 3.81 5.2405 0.9996 3123632 ChemDiv3_015867 CN1C(=CC(=NS1(=O)=O)c2ccco2)C(=O)NCC3(CC4CC5CC(C4)C3)C5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B06 compound treatment 0.444 0.196 2.05 0.348 0.117 1.4 2.4398 0.9824 3042969 ChemDiv3_015868 CCCNC(=O)c1nnc(Cc2ccc3OCOc3c2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B07 compound treatment 0.229 -0.0195 -0.2 0.213 -0.0182 -0.22 -0.299 -0.9995 3123633 ChemDiv3_015869 COC(=O)c1cc(cn1C)S(=O)(=O)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B08 compound treatment 0.235 -0.0135 -0.14 0.192 -0.0393 -0.47 -0.4321 -0.881 3123634 ChemDiv3_015870 COc1ccccc1Cn2ccn(CC(=O)NCCc3ccccc3)c(=O)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B09 compound treatment 0.239 -0.00947 -0.1 0.215 -0.0163 -0.19 -0.2078 -0.9515 3042972 ChemDiv3_015871 Cn1nc(C(=O)NCCCN2CCN(CC2)c3ccccc3)c4COc5ccccc5-c41 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B10 compound treatment 0.189 -0.0595 -0.62 0.169 -0.0623 -0.74 -0.9683 -0.9962 3123635 ChemDiv3_015872 CCCN1CCN(CC1)C(=O)c2sc3nc4CCCCn4c(=O)c3c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B11 compound treatment 0.268 0.0195 0.21 0.196 -0.0352 -0.42 -0.1532 -0.3266 3123636 ChemDiv3_015873 COC(=O)NCC(N1CCOCC1)c2cccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B12 compound treatment 0.162 -0.0865 -0.91 0.154 -0.0772 -0.92 -1.2957 -1.0 3042974 ChemDiv3_015874 CC1CC(C)CN(CCCNC(=O)c2cccc3C(=O)CCSc23)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B13 compound treatment 0.213 -0.0355 -0.37 0.155 -0.0762 -0.91 -0.9085 -0.9219 3123637 ChemDiv3_015875 CCC(=O)Nc1nn2c(C)nnc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B14 compound treatment 0.401 0.153 1.6 0.364 0.133 1.59 2.2559 1.0 3123638 ChemDiv3_015876 Cc1ccc(N2CCN(CC2)C(=O)c3nc(no3)c4ccncc4)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B15 compound treatment 0.37 0.122 1.28 0.309 0.0778 0.93 1.5603 0.9879 3042976 ChemDiv3_015877 CCOC(=O)CSc1nc2nccnc2c(=O)n1CCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B16 compound treatment 0.302 0.0535 0.56 0.279 0.0478 0.57 0.8015 1.0 3123639 ChemDiv3_015878 CC1CN(C(=O)N2CCCC(C2)C(=O)NCCCc3ccccc3)c4cc(C)ccc4O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B17 compound treatment 0.271 0.0225 0.24 0.297 0.0658 0.79 0.7236 0.8808 3042978 ChemDiv3_015879 CCc1ccc(NS(=O)(=O)c2ccc3N(C)CCOc3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B18 compound treatment 0.62 0.372 3.9 0.526 0.295 3.53 5.2528 0.9987 3123640 ChemDiv3_015880 Cn1cc(CCCC(=O)N2CCCC2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B19 compound treatment 0.349 0.101 1.06 0.321 0.0897 1.07 1.5059 1.0 3042980 ChemDiv3_015881 CCN(c1ccccc1)S(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B20 compound treatment 0.753 0.505 5.3 0.707 0.476 5.69 7.7718 0.9994 3123641 ChemDiv3_015882 Oc1ccccc1c2cc(on2)C(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B21 compound treatment 0.387 0.139 1.45 0.395 0.164 1.96 2.4142 0.9893 3123642 ChemDiv3_015883 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)NC(C)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B22 compound treatment 0.285 0.0365 0.38 0.274 0.0428 0.51 0.633 0.99 3042982 ChemDiv3_015884 Cc1cc2NC(=O)COc2cc1S(=O)(=O)NC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B23 mock treatment 0.308 0.0595 0.63 0.259 0.0278 0.33 0.6769 0.9561 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 B24 mock treatment 0.269 0.0205 0.22 0.243 0.0118 0.14 0.2519 0.9785 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C01 compound treatment 0.359 0.111 1.16 0.328 0.0968 1.16 1.6394 1.0 3043012 ChemDiv3_015885 O=C(CCCN1C(=O)c2ccccc2C1=O)N(Cc3nc(no3)c4ccccc4)C5CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C02 compound treatment 0.147 -0.101 -1.07 0.137 -0.0943 -1.13 -1.5509 -0.9996 3043014 ChemDiv3_015886 Oc1ccc(cc1)c2nc(c([nH]2)c3ccc(O)cc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C03 compound treatment 0.625 0.377 3.95 0.496 0.265 3.17 5.0361 0.994 3043015 ChemDiv3_015887 Cc1cccc(c1)c2noc(CNC(=O)C(C)(C)Oc3ccc(Cl)cc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C04 compound treatment 0.226 -0.0225 -0.24 0.235 0.00375 0.04 -0.1351 -0.5626 3043017 ChemDiv3_015888 CC1CC(C)CN(C1)C(=O)Cn2ncc3ccc(C)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C05 compound treatment 0.424 0.176 1.84 0.395 0.164 1.96 2.6889 0.9995 3043018 ChemDiv3_015889 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)NCc3nc(no3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C06 compound treatment 0.733 0.485 5.09 0.717 0.486 5.81 7.7079 0.9978 3043019 ChemDiv3_015890 Cc1ccc2n(ncc2c1)C(=O)CCCC(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C07 compound treatment 0.58 0.332 3.48 0.541 0.31 3.71 5.0826 0.9995 3123643 ChemDiv3_015891 CC(C)C(=O)n1nc(nc1NCc2cccs2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C08 compound treatment 0.103 -0.145 -1.53 0.104 -0.127 -1.52 -2.1569 -1.0 3043021 ChemDiv3_015892 O=C(CCC(=O)n1ncc2ccccc12)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C09 compound treatment 0.25 0.00153 0.02 0.207 -0.0243 -0.29 -0.1938 -0.6669 3123644 ChemDiv3_015893 CC(C)CCn1c(CNC(=O)c2ccccc2)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C10 compound treatment 0.193 -0.0555 -0.58 0.18 -0.0512 -0.61 -0.8455 -0.9997 3123645 ChemDiv3_015894 O=C(NCc1c(sc2CCCCc12)n3cccc3)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C11 compound treatment 0.294 0.0455 0.48 0.241 0.00975 0.12 0.4206 0.8545 3043024 ChemDiv3_015895 CCOc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3Cc5ccc(F)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C12 compound treatment 0.916 0.668 7.01 0.906 0.675 8.07 10.6659 0.9975 3123646 ChemDiv3_015896 CCc1ccc(NC(=O)Nc2ccc3Sc4ccccc4C(=O)N(C)c3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C13 compound treatment 0.303 0.0545 0.57 0.3 0.0688 0.82 0.9866 0.9843 3043026 ChemDiv3_015897 CNC(=O)CCCc1nc(no1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C14 compound treatment 0.724 0.476 4.99 0.672 0.441 5.27 7.2603 0.9996 3123647 ChemDiv3_015898 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)Nc4ccc(CC)cc4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C15 compound treatment 0.254 0.00553 0.06 0.21 -0.0213 -0.25 -0.1387 -0.5318 3043029 ChemDiv3_015899 C1Cc2nc3nncn3c(Nc4ccccc4)c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C16 compound treatment 0.787 0.539 5.66 0.758 0.527 6.3 8.4558 0.9985 3123648 ChemDiv3_015900 Fc1ccc(CNC(=O)CCSCc2cnn(c2n3cccc3)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C17 compound treatment 0.55 0.302 3.17 0.452 0.221 2.64 4.1069 0.9959 3043031 ChemDiv3_015901 C1CCN(C1)c2cc(nc3nncn23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C18 compound treatment 0.557 0.309 3.24 0.494 0.263 3.14 4.5142 0.9999 3123649 ChemDiv3_015902 CCOc1ccccc1CNC(=O)CCC(=O)N2CC(C)Oc3ccc(Cl)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C19 compound treatment 0.2 -0.0485 -0.51 0.218 -0.0133 -0.16 -0.4721 -0.8854 3043033 ChemDiv3_015903 CC(C)Cn1c(nc2ccccc12)C3CN(CC=C)C(=O)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C20 compound treatment 0.364 0.116 1.21 0.341 0.11 1.31 1.7865 0.9992 3123650 ChemDiv3_015904 COc1ccc(cc1)c2cc3c(=O)n(CC(=O)NC4CCC(C)CC4)ncn3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C21 compound treatment 0.365 0.117 1.22 0.329 0.0978 1.17 1.6924 0.9997 3123651 ChemDiv3_015905 CN(Cc1nc(no1)c2ccc(C)cc2)C(=O)Nc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C22 compound treatment 0.265 0.0165 0.17 0.254 0.0227 0.27 0.3152 0.9764 3043036 ChemDiv3_015906 CN(CC(=O)NC1CCCCC1)c2nnc(s2)N3CCCC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C23 mock treatment 0.235 -0.0135 -0.14 0.27 0.0388 0.46 0.2278 0.47 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 C24 mock treatment 0.259 0.0105 0.11 0.274 0.0428 0.51 0.4399 0.8406 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D01 compound treatment 0.217 -0.0315 -0.33 0.221 -0.0103 -0.12 -0.3204 -0.9089 3123652 ChemDiv3_015907 CN1C(=CC(=NS1(=O)=O)c2ccc(C)cc2)C(=O)NCC=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D02 compound treatment 0.219 -0.0295 -0.31 0.181 -0.0503 -0.6 -0.644 -0.9523 3043069 ChemDiv3_015908 CCc1ccccc1NC(=O)Cc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D03 compound treatment 0.385 0.137 1.43 0.348 0.117 1.4 2.0017 0.9999 3043071 ChemDiv3_015909 CN1C(=CC(=NS1(=O)=O)c2ccc(F)cc2)C(=O)Nc3ccc(F)cc3F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D04 compound treatment 0.268 0.0195 0.21 0.242 0.0107 0.13 0.236 0.9747 3043072 ChemDiv3_015910 COc1cc(OC)c(NC(=O)Cc2noc3ccc(C)cc23)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D05 compound treatment 0.416 0.168 1.76 0.362 0.131 1.56 2.3503 0.9983 3043074 ChemDiv3_015911 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)Nc3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D06 compound treatment 0.189 -0.0595 -0.62 0.168 -0.0633 -0.76 -0.9767 -0.9955 3043076 ChemDiv3_015912 O=C(NCCCN1CCOCC1)c2nnc(o2)c3ccc4OCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D07 compound treatment 0.156 -0.0925 -0.97 0.132 -0.0993 -1.19 -1.5264 -0.995 3043077 ChemDiv3_015913 O=C(CSc1nc2CCN(Cc3ccccc3)Cc2c(=O)[nH]1)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D08 compound treatment 0.427 0.179 1.88 0.313 0.0818 0.98 2.0175 0.954 3043079 ChemDiv3_015914 COc1ccc(Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D09 compound treatment 0.333 0.0845 0.89 0.304 0.0727 0.87 1.2432 1.0 3123653 ChemDiv3_015915 Cn1nc(C(=O)N2CCCC2)c3CSc4ccccc4-c31 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D10 compound treatment 0.536 0.288 3.02 0.471 0.24 2.87 4.1637 0.9997 3043081 ChemDiv3_015916 CN(C(=O)c1sc2nc3CCCCn3c(=O)c2c1C)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D11 compound treatment 0.167 -0.0815 -0.86 0.13 -0.101 -1.21 -1.4616 -0.9855 3123654 ChemDiv3_015917 COc1cccc(c1)c2nnc3sc(NC(=O)C)nn23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D12 compound treatment 0.335 0.0865 0.91 0.272 0.0408 0.49 0.9874 0.9574 3043082 ChemDiv3_015918 CN(C(=O)c1cccc2C(=O)CCSc12)c3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D13 compound treatment 0.365 0.117 1.22 0.315 0.0838 1.0 1.574 0.9951 3123655 ChemDiv3_015919 CCCCC(=O)Nc1nn2c(nnc2s1)c3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D14 compound treatment 0.103 -0.145 -1.53 0.098 -0.133 -1.59 -2.2076 -0.9998 3123656 ChemDiv3_015920 CN(Cc1ccccc1)C(=O)c2nc(no2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D15 compound treatment 0.823 0.575 6.03 0.919 0.688 8.23 10.0852 0.9884 3043085 ChemDiv3_015921 COc1cccc(CSc2nc3nccnc3c(=O)n2CCc4ccccc4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D16 compound treatment 0.891 0.643 6.75 0.874 0.643 7.69 10.2095 0.9979 3123657 ChemDiv3_015922 CCOC(=O)Cc1ccc(NC(=O)N2CCOc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D17 compound treatment 0.311 0.0625 0.66 0.246 0.0147 0.18 0.5892 0.8664 3123762 ChemDiv3_015923 Cn1cc(cc1C(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D18 compound treatment 0.249 5.31E-4 0.01 0.197 -0.0343 -0.41 -0.2858 -0.6974 3043087 ChemDiv3_015924 CCn1cc(CCCC(=O)NCCN2CCN(C)CC2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D19 compound treatment 0.383 0.135 1.41 0.369 0.138 1.65 2.1645 0.9971 3123763 ChemDiv3_015925 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D20 compound treatment 0.355 0.107 1.12 0.328 0.0968 1.16 1.6097 0.9999 3043089 ChemDiv3_015926 Oc1ccccc1c2cc(on2)C(=O)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D21 compound treatment 0.559 0.311 3.26 0.521 0.29 3.47 4.7575 0.9995 3123764 ChemDiv3_015927 Fc1ccc(NC(=O)Cc2noc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D22 compound treatment 0.251 0.00253 0.03 0.247 0.0158 0.19 0.152 0.799 3123765 ChemDiv3_015928 COc1ccc(CCNS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D23 mock treatment 0.278 0.0295 0.31 0.254 0.0227 0.27 0.4118 0.9979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 D24 mock treatment 0.258 0.00953 0.1 0.256 0.0248 0.3 0.2802 0.8963 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E01 compound treatment 0.238 -0.0105 -0.11 0.213 -0.0182 -0.22 -0.2321 -0.9496 3043091 ChemDiv3_015929 CC(C)N(Cc1nc(no1)c2cccc(C)c2)C(=O)C3CCC(=O)N3S(=O)(=O)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E02 compound treatment 0.424 0.176 1.84 0.404 0.173 2.07 2.7651 0.9984 3123766 ChemDiv3_015930 Brc1ccc(s1)c2nc(c3cccs3)c([nH]2)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E03 compound treatment 0.595 0.347 3.64 0.572 0.341 4.08 5.4563 0.9984 3043093 ChemDiv3_015931 O=S(=O)(NCc1nc(no1)c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E04 compound treatment 0.26 0.0115 0.12 0.228 -0.00325 -0.04 0.0581 0.4571 3043129 ChemDiv3_015932 CCc1ccc(NC(=O)Nc2nnc(s2)N(CC(C)C)CC(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E05 compound treatment 0.125 -0.123 -1.3 0.105 -0.126 -1.51 -1.985 -0.9971 3043130 ChemDiv3_015933 C(NC1CCCCC1)c2nc(no2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E06 compound treatment 0.715 0.467 4.9 0.619 0.388 4.64 6.7451 0.9996 3043132 ChemDiv3_015934 Clc1ccc2cnn(C(=O)CCC(=O)NC3CCCc4ccccc34)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E07 compound treatment 0.399 0.151 1.58 0.379 0.148 1.77 2.3679 0.9984 1686198 ChemDiv3_015935 O=c1cc(nc2SCCCn21)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E08 compound treatment 0.351 0.103 1.08 0.34 0.109 1.3 1.6815 0.9956 3043133 ChemDiv3_015936 CCc1ccc(NC(=O)n2ncc3c(C)cccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E09 compound treatment 0.775 0.527 5.53 0.675 0.444 5.31 7.6645 0.9998 3043135 ChemDiv3_015937 CC(Oc1ccccc1)c2nc3ccccc3n2CCOc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E10 compound treatment 0.13 -0.118 -1.24 0.11 -0.121 -1.45 -1.9056 -0.9971 3043136 ChemDiv3_015938 CN(Cc1ccccc1)c2nnc(NC(=O)NCc3ccccc3)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E11 compound treatment 0.146 -0.102 -1.08 0.113 -0.118 -1.41 -1.7614 -0.9909 3123767 ChemDiv3_015939 N=C1SC2CS(=O)(=O)CC2N1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E12 compound treatment 0.558 0.31 3.25 0.503 0.272 3.25 4.5978 1.0 3123768 ChemDiv3_015940 CN1C(=O)c2ccccc2Sc3ccc(NC(=O)NCc4ccc(C)cc4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E13 compound treatment 0.512 0.264 2.77 0.4 0.169 2.02 3.3848 0.988 3043139 ChemDiv3_015941 CC(C)NC(=O)CCCc1nc(no1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E14 compound treatment 0.428 0.18 1.89 0.325 0.0938 1.12 2.1264 0.9692 3123769 ChemDiv3_015942 CCCNC(=O)Nc1ccc2Sc3ccccc3C(=O)N(CC)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E15 compound treatment 0.12 -0.128 -1.35 0.114 -0.117 -1.4 -1.946 -0.9998 3043141 ChemDiv3_015943 CC(C)CCNc1c2CCCc2nc3nncn13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E16 compound treatment 0.785 0.537 5.64 0.833 0.602 7.2 9.0754 0.9927 3123770 ChemDiv3_015944 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NCc4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E17 compound treatment 0.549 0.301 3.16 0.462 0.231 2.76 4.1841 0.9978 3043143 ChemDiv3_015945 COc1ccc(Nc2cc(nc3nncn23)c4ccccc4)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E18 compound treatment 0.276 0.0275 0.29 0.238 0.00675 0.08 0.2616 0.8713 3123771 ChemDiv3_015946 CNC(=O)CCC(=O)N1CCOc2ccc(C)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E19 compound treatment 0.283 0.0345 0.36 0.278 0.0468 0.56 0.652 0.978 3123772 ChemDiv3_015947 Fc1ccc(Cn2c(nc3ccccc23)C4CN(CC=C)C(=O)C4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E20 compound treatment 0.324 0.0755 0.79 0.262 0.0308 0.37 0.8211 0.939 3043146 ChemDiv3_015948 CCc1ccc(cc1)c2cc3c(=O)n(CC(=O)NC4CCCC(C)C4C)nc(C)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E21 compound treatment 0.658 0.41 4.3 0.66 0.429 5.13 6.6687 0.9962 3123773 ChemDiv3_015949 CCN(Cc1nc(no1)c2ccc(C)cc2)C(=O)Nc3ccccc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E22 compound treatment 0.238 -0.0105 -0.11 0.19 -0.0413 -0.49 -0.4267 -0.8439 3043148 ChemDiv3_015950 CN(Cc1ccccc1)C(=O)Cn2ncn3cccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E23 mock treatment 0.279 0.0305 0.32 0.221 -0.0103 -0.12 0.14 0.4079 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 E24 mock treatment 0.271 0.0225 0.24 0.258 0.0267 0.32 0.3936 0.989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F01 compound treatment 0.587 0.339 3.56 0.481 0.25 2.99 4.627 0.9963 3123774 ChemDiv3_015951 COc1ccc(cc1)C2=NS(=O)(=O)N(C)C(=C2)C(=O)N(C)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F02 compound treatment 1.299 1.05 11.03 1.271 1.04 12.44 16.5982 0.9982 3123775 ChemDiv3_015952 CCOC(=O)c1ccc(NC(=O)Cc2noc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F03 compound treatment 0.212 -0.0365 -0.38 0.202 -0.0293 -0.35 -0.5183 -0.999 3043150 ChemDiv3_015953 CN1C(=CC(=NS1(=O)=O)c2ccc(F)cc2)C(=O)N3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F04 compound treatment 0.267 0.0185 0.19 0.255 0.0238 0.28 0.3386 0.983 3123776 ChemDiv3_015954 Cc1ccc2onc(CC(=O)NCc3cccc(Cl)c3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F05 compound treatment 0.454 0.206 2.16 0.393 0.162 1.94 2.8948 0.9985 3123777 ChemDiv3_015955 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F06 compound treatment 0.266 0.0175 0.18 0.183 -0.0483 -0.58 -0.278 -0.4588 3043187 ChemDiv3_015956 OCCNC(=O)c1nnc(o1)c2ccc3OCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F07 compound treatment 0.482 0.234 2.45 0.404 0.173 2.07 3.1958 0.9964 3043189 ChemDiv3_015957 CSc1cccc(c1)n2nnc(C(=O)N)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F08 compound treatment 0.241 -0.00747 -0.08 0.197 -0.0343 -0.41 -0.3452 -0.8274 3043191 ChemDiv3_015958 O=C(Cn1ccn(c2ccccc2)c(=O)c1=O)NCCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F09 compound treatment 0.724 0.476 4.99 0.713 0.482 5.76 7.6072 0.9975 3043192 ChemDiv3_015959 CCCCN(C)C(=O)c1nn(C)c-2c1CSc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F10 compound treatment 0.16 -0.0885 -0.93 0.132 -0.0993 -1.19 -1.4967 -0.9926 3043193 ChemDiv3_015960 Cc1c(sc2nc3CCCCn3c(=O)c12)C(=O)N4CCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F11 compound treatment 0.102 -0.146 -1.54 0.116 -0.115 -1.38 -2.0628 -0.9985 3043195 ChemDiv3_015961 COc1ccc(cc1)C(=O)Nc2nn3c(CC(C)C)nnc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F12 compound treatment 0.317 0.0685 0.72 0.278 0.0468 0.56 0.9045 0.9922 3043196 ChemDiv3_015962 CCOc1ccc(CCNC(=O)c2cccc3C(=O)CCSc23)cc1OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F13 compound treatment 0.257 0.00853 0.09 0.191 -0.0403 -0.48 -0.2772 -0.5658 3123778 ChemDiv3_015963 CNC(=O)c1cc([nH]c1C)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F14 compound treatment 0.201 -0.0475 -0.5 0.157 -0.0742 -0.89 -0.9807 -0.9627 3043198 ChemDiv3_015964 CN(C)CCNC(=O)c1nc(no1)c2cccnc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F15 compound treatment 0.402 0.154 1.61 0.321 0.0897 1.07 1.8995 0.9805 3123779 ChemDiv3_015965 CCc1ccc(NC(=O)CSc2nc3nccnc3c(=O)n2CCC(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F16 compound treatment 0.698 0.45 4.72 0.558 0.327 3.91 6.1028 0.9956 3043200 ChemDiv3_015966 O=C(NCc1ccccc1)N2CCOc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F17 compound treatment 0.351 0.103 1.08 0.331 0.0998 1.19 1.6053 0.9987 3123780 ChemDiv3_015967 Cn1cc(cc1C(=O)N2CCc3ccccc3C2)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F18 compound treatment 0.768 0.52 5.46 0.717 0.486 5.81 7.9678 0.9995 3123781 ChemDiv3_015968 CCn1cc(CCCC(=O)NCc2cc(Br)ccc2OC)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F19 compound treatment 0.336 0.0875 0.92 0.383 0.152 1.82 1.9339 0.9503 3043203 ChemDiv3_015969 CCCCN(C)S(=O)(=O)c1ccc2N(CCOc2c1)C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F20 compound treatment 0.621 0.373 3.91 0.601 0.37 4.42 5.8947 0.9981 3123782 ChemDiv3_015970 CCC(C)NC(=O)c1cc(no1)c2ccccc2O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F21 compound treatment 0.493 0.245 2.57 0.42 0.189 2.26 3.4129 0.9979 3043205 ChemDiv3_015971 CC1CCN(CC1)C(=O)Cc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F22 compound treatment 0.329 0.0805 0.85 0.271 0.0398 0.48 0.9344 0.9629 3123783 ChemDiv3_015972 Cc1ccc(C)c(c1)N2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F23 mock treatment 0.272 0.0235 0.25 0.273 0.0418 0.5 0.528 0.9473 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 F24 mock treatment 0.25 0.00153 0.02 0.231 -2.5E-4 0.0 0.0093 0.5659 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G01 compound treatment 0.281 0.0325 0.34 0.288 0.0568 0.68 0.7217 0.9495 3043206 ChemDiv3_015973 COc1ccc(cc1)c2noc(CN(C(C)C)C(=O)CN3C(=O)c4ccccc4C3=O)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G02 compound treatment 0.178 -0.0705 -0.74 0.148 -0.0833 -1.0 -1.2276 -0.9893 3123784 ChemDiv3_015974 CCC(O)c1nc2ccccc2n1CCOc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G03 compound treatment 0.802 0.554 5.81 0.767 0.536 6.41 8.6433 0.9988 3043208 ChemDiv3_015975 O=C(CSc1ccccc1)NCc2nc(no2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G04 compound treatment 0.216 -0.0325 -0.34 0.186 -0.0452 -0.54 -0.624 -0.9752 3123785 ChemDiv3_015976 CCc1ccc(NC(=O)Nc2nnc(s2)N3CCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G05 compound treatment 0.629 0.381 4.0 0.471 0.24 2.87 4.8543 0.9868 3123786 ChemDiv3_015977 COc1ccc(cc1)c2noc(CN3C(=O)c4ccccc4C3=O)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G06 compound treatment 0.127 -0.121 -1.28 0.174 -0.0573 -0.68 -1.3864 -0.9575 3043210 ChemDiv3_015978 CC1CCCCN1C(=O)CCC(=O)n2ncc3cc(C)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G07 compound treatment 0.578 0.33 3.46 0.485 0.254 3.04 4.594 0.9979 3123787 ChemDiv3_015979 CC(C)(C)OC(=O)N1CCC(CC1)c2nc(O)c3nnn(Cc4ccccc4Cl)c3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G08 compound treatment 0.365 0.117 1.22 0.249 0.0177 0.21 1.0156 0.8176 3043213 ChemDiv3_015980 COC(=O)c1ccccc1NC(=O)n2ncc3c(C)cccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G09 compound treatment 0.344 0.0955 1.0 0.295 0.0638 0.76 1.2488 0.9908 3123788 ChemDiv3_015981 CC(Oc1cccc(C)c1)c2nc3ccccc3n2CC=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G10 compound treatment 0.781 0.533 5.59 0.771 0.54 6.46 8.5212 0.9974 3043255 ChemDiv3_015982 CCCN(Cc1cccs1)C(=O)Nc2ccccc2CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G11 compound treatment 0.232 -0.0165 -0.17 0.194 -0.0372 -0.45 -0.4374 -0.915 3043257 ChemDiv3_015983 CC(=O)/N=C/1\SC2CS(=O)(=O)CC2N1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G12 compound treatment 0.348 0.0995 1.05 0.294 0.0628 0.75 1.27 0.9868 3043258 ChemDiv3_015984 CCCNC(=O)Nc1ccc2Sc3ccccc3C(=O)N(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G13 compound treatment 0.227 -0.0215 -0.23 0.204 -0.0273 -0.33 -0.39 -0.9838 3043260 ChemDiv3_015985 NC(=O)CCCc1nc(no1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G14 compound treatment 0.334 0.0855 0.9 0.252 0.0208 0.25 0.8107 0.8699 3043261 ChemDiv3_015986 NC(=O)C1CCN(CC1)C(=O)CSCc2cnn(c2n3cccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G15 compound treatment 0.23 -0.0185 -0.19 0.18 -0.0512 -0.61 -0.5707 -0.8874 3043263 ChemDiv3_015987 CCN(CC)c1c2CCCc2nc3nncn13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G16 compound treatment 0.312 0.0635 0.67 0.288 0.0568 0.68 0.9519 1.0 3043264 ChemDiv3_015988 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)N4CCN(CC4)c5ccc(Cl)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G17 compound treatment 0.407 0.159 1.66 0.349 0.118 1.41 2.1735 0.9965 3123789 ChemDiv3_015989 Fc1ccc(cc1)S(=O)(=O)N2CCC(CC2)c3ccc(=O)n(n3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G18 compound treatment 0.463 0.215 2.25 0.352 0.121 1.44 2.6148 0.9769 3043266 ChemDiv3_015990 CC1CN(C(=O)CCC(=O)N(C)Cc2ccccc2)c3ccccc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G19 compound treatment 0.745 0.497 5.21 0.708 0.477 5.7 7.7209 0.999 3123790 ChemDiv3_015991 Cc1ccc(C)c(Cn2ncc3ccccc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G20 compound treatment 0.357 0.109 1.14 0.334 0.103 1.23 1.6753 0.9993 3123902 ChemDiv3_015992 CCc1ccc(cc1)c2cc3c(=O)n(CC(=O)NC(C)CCc4ccccc4)nc(C)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G21 compound treatment 0.665 0.417 4.37 0.577 0.346 4.14 6.0185 0.9996 3043268 ChemDiv3_015993 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G22 compound treatment 0.541 0.293 3.07 0.482 0.251 3.0 4.2939 0.9999 3123903 ChemDiv3_015994 CCOc1ccc(CCNC(=O)Cn2nc(C)n3cccc3c2=O)cc1OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G23 mock treatment 0.264 0.0155 0.16 0.235 0.00375 0.04 0.1471 0.8693 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 G24 mock treatment 0.244 -0.00447 -0.05 0.242 0.0107 0.13 0.0578 0.4219 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H01 compound treatment 0.215 -0.0335 -0.35 0.17 -0.0612 -0.73 -0.7667 -0.9434 3043270 ChemDiv3_015995 CCC1CCCCN1C(=O)C2=CC(=NS(=O)(=O)N2C)c3ccc(OC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H02 compound treatment 1.318 1.07 11.23 1.305 1.07 12.85 17.027 0.9978 3123904 ChemDiv3_015996 Cc1ccc(CCNC(=O)Cc2noc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H03 compound treatment 0.287 0.0385 0.4 0.208 -0.0233 -0.28 0.0895 0.1822 3123905 ChemDiv3_015997 CN1C(=CC(=NS1(=O)=O)c2ccc(F)cc2)C(=O)NC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H04 compound treatment 0.232 -0.0165 -0.17 0.276 0.0447 0.54 0.2563 0.4555 3043272 ChemDiv3_015998 CN1CCN(CCNC(=O)Cc2noc3ccc(C)cc23)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H05 compound treatment 0.261 0.0125 0.13 0.218 -0.0133 -0.16 -0.019 -0.0924 3123906 ChemDiv3_015999 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H06 compound treatment 0.255 0.00653 0.07 0.259 0.0278 0.33 0.2833 0.8356 3043274 ChemDiv3_016000 O=C(Cn1ccn(Cc2ccccc2)c(=O)c1=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H07 compound treatment 0.234 -0.0145 -0.15 0.205 -0.0262 -0.31 -0.3295 -0.9445 3123907 ChemDiv3_016001 CCOc1ccccc1n2nnc(C(=O)N)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H08 compound treatment 0.206 -0.0425 -0.45 0.178 -0.0532 -0.64 -0.7659 -0.9848 3123908 ChemDiv3_016002 Fc1ccc(cc1)C(=O)Cn2ccn(c3ccccc3)c(=O)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H09 compound treatment 0.824 0.576 6.04 0.873 0.642 7.68 9.7035 0.993 3043276 ChemDiv3_016003 CN(C(=O)c1nn(C)c-2c1CSc3ccccc23)c4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H10 compound treatment 0.361 0.113 1.18 0.331 0.0998 1.19 1.6796 1.0 3123909 ChemDiv3_016004 Cc1c(sc2nc3CCCCn3c(=O)c12)C(=O)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H11 compound treatment 0.722 0.474 4.97 0.651 0.42 5.02 7.0678 1.0 3043278 ChemDiv3_016005 COc1ccccc1C(=O)Nc2nn3c(nnc3s2)c4ccccc4C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H12 compound treatment 0.371 0.123 1.29 0.352 0.121 1.44 1.9315 0.9983 3123910 ChemDiv3_016006 C=CCN(C(=O)c1cccc2C(=O)CCSc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H13 compound treatment 0.578 0.33 3.46 0.453 0.222 2.65 4.3233 0.9914 3123911 ChemDiv3_016007 Cc1[nH]c(cc1C(=O)N2CCCCC2)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H14 compound treatment 0.221 -0.0275 -0.29 0.187 -0.0442 -0.53 -0.5784 -0.9592 3043280 ChemDiv3_016008 O=C(N1CCOCC1)c2nc(no2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H15 compound treatment 0.593 0.345 3.62 0.546 0.315 3.77 5.2215 0.9998 3123912 ChemDiv3_016009 CC(C)CCn1c(SCc2ccc(F)cc2)nc3nccnc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H16 compound treatment 0.772 0.524 5.5 0.765 0.534 6.39 8.4036 0.9972 3043331 ChemDiv3_016010 Cc1ccc2OCCN(C(=O)Nc3cc(C)cc(C)c3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H17 compound treatment 0.332 0.0835 0.88 0.228 -0.00325 -0.04 0.5928 0.6751 3043332 ChemDiv3_016011 Cn1cc(cc1C(=O)N2CCCc3ccccc23)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H18 compound treatment 0.858 0.61 6.4 0.782 0.551 6.59 9.1861 0.9999 3043333 ChemDiv3_016012 Cc1ccc(Cn2cc(CCCC(=O)N3CCCC3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H19 compound treatment 0.407 0.159 1.66 0.349 0.118 1.41 2.1735 0.9965 3043335 ChemDiv3_016013 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)NCCc3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H20 compound treatment 0.586 0.338 3.54 0.591 0.36 4.3 5.5502 0.9954 3043336 ChemDiv3_016014 CC(C)CNC(=O)c1cc(no1)c2ccccc2O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H21 compound treatment 0.341 0.0925 0.97 0.345 0.114 1.36 1.6495 0.9864 3043338 ChemDiv3_016015 COc1ccccc1CNC(=O)Cc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H22 compound treatment 0.197 -0.0515 -0.54 0.175 -0.0563 -0.67 -0.8581 -0.9941 3043339 ChemDiv3_016016 CCCCN(C)S(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H23 mock treatment 0.26 0.0115 0.12 0.257 0.0257 0.31 0.3035 0.9168 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 H24 mock treatment 0.272 0.0235 0.25 0.249 0.0177 0.21 0.3249 0.9971 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I01 compound treatment 0.683 0.435 4.56 0.559 0.328 3.92 5.9999 0.9971 3123913 ChemDiv3_016017 O=C(NCc1nc(no1)c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I02 compound treatment 0.183 -0.0655 -0.69 0.201 -0.0302 -0.36 -0.7421 -0.9551 3123914 ChemDiv3_016018 CCC1N(CCn2c(C)ccc12)C(=O)Nc3ccc(CC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I03 compound treatment 0.758 0.51 5.35 0.7 0.469 5.61 7.7497 0.9997 3043341 ChemDiv3_016019 Cc1ccc(cc1)c2noc(CNC(=O)CC3CCCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I04 compound treatment 0.514 0.266 2.79 0.501 0.27 3.23 4.2541 0.9974 3123915 ChemDiv3_016020 Clc1ccc2cnn(CC(=O)N3CCCCC3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I05 compound treatment 0.218 -0.0305 -0.32 0.183 -0.0483 -0.58 -0.6345 -0.9613 3043343 ChemDiv3_016021 CC(C)(C)OC(=O)N1CCN(CC1)c2ncnc3[nH]cnc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I06 compound treatment 0.397 0.149 1.56 0.311 0.0798 0.95 1.7778 0.9722 3123916 ChemDiv3_016022 Cc1oc(nc1CN2C(=O)CN=C(c3ccccc3)c4ccccc24)c5cccs5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I07 compound treatment 0.446 0.198 2.07 0.373 0.142 1.7 2.6662 0.995 3123917 ChemDiv3_016023 COc1cccc(Cn2nnc3c(O)nc(nc23)C4CCN(CC4)C(=O)c5ccccc5)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I08 compound treatment 0.261 0.0125 0.13 0.204 -0.0273 -0.33 -0.1375 -0.391 3043346 ChemDiv3_016024 CCc1ccc(CNC(=O)CCC(=O)n2ncc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I09 compound treatment 0.226 -0.0225 -0.24 0.217 -0.0143 -0.17 -0.2874 -0.9873 3123918 ChemDiv3_016025 CCC(Oc1cccc(C)c1)c2nc3ccccc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I10 compound treatment 0.449 0.201 2.11 0.464 0.233 2.78 3.4583 0.9905 3043348 ChemDiv3_016026 CCCN(Cc1cccs1)C(=O)Nc2cc(OC)cc(OC)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I11 compound treatment 0.235 -0.0135 -0.14 0.221 -0.0103 -0.12 -0.1867 -0.9975 3123919 ChemDiv3_016027 CC(C)C(=O)/N=C/1\SC2CS(=O)(=O)CC2N1CCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I12 compound treatment 0.577 0.329 3.45 0.521 0.29 3.47 4.8912 1.0 3123920 ChemDiv3_016028 CC(NC(=O)Nc1ccc2Sc3ccccc3C(=O)N(C)c2c1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I13 compound treatment 0.555 0.307 3.22 0.446 0.215 2.57 4.0933 0.9938 3043350 ChemDiv3_016029 O=C(CCCc1nc(no1)c2ccccc2)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I14 compound treatment 0.168 -0.0805 -0.85 0.136 -0.0953 -1.14 -1.4034 -0.9892 3123921 ChemDiv3_016030 O=C(CSCc1cnn(c1n2cccc2)c3ccccc3)N4CCC(CC4)N5CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I15 compound treatment 0.597 0.349 3.66 0.449 0.218 2.61 4.4306 0.9861 3043352 ChemDiv3_016031 CC(C)Nc1cc(nc2nncn12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I16 compound treatment 0.348 0.0995 1.05 0.331 0.0998 1.19 1.5831 0.9978 3123922 ChemDiv3_016032 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)NCc4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I17 compound treatment 0.263 0.0145 0.15 0.218 -0.0133 -0.16 -0.0042 -0.019 3043354 ChemDiv3_016033 CCCc1ccc(cc1)S(=O)(=O)N2CCC(CC2)c3ccc(=O)n(n3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I18 compound treatment 0.09 -0.158 -1.66 0.075 -0.156 -1.87 -2.4988 -0.9983 3123923 ChemDiv3_016034 CC1CN(C(=O)CCC(=O)N2CCN(CC2)c3ccccn3)c4ccccc4O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I19 compound treatment 0.469 0.221 2.32 0.391 0.16 1.91 2.9893 0.9954 3123924 ChemDiv3_016035 COc1ccc(cc1OC)C2=Nc3cc(ccc3NC(=N2)c4ccncc4)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I20 compound treatment 0.271 0.0225 0.24 0.275 0.0437 0.52 0.5375 0.9356 3043356 ChemDiv3_016036 CCc1ccc(cc1)c2cc3c(=O)n(CC(=O)NCCN4CCOCC4)nc(C)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I21 compound treatment 0.311 0.0625 0.66 0.311 0.0798 0.95 1.1391 0.9834 3043415 ChemDiv3_016037 Clc1ccc(cc1)c2noc(CNC(=O)NC3CCCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I22 compound treatment 0.097 -0.151 -1.59 0.106 -0.125 -1.5 -2.1845 -0.9996 3043416 ChemDiv3_016038 CC(C(=O)N1CCN(CC1)c2ccccn2)n3ncn4cccc4c3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I23 mock treatment 0.234 -0.0145 -0.15 0.194 -0.0372 -0.45 -0.4226 -0.8975 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 I24 mock treatment 0.293 0.0445 0.47 0.271 0.0398 0.48 0.667 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J01 compound treatment 0.229 -0.0195 -0.2 0.211 -0.0203 -0.24 -0.3159 -0.9964 3043418 ChemDiv3_016039 CCN(CC)C(=O)C1=CC(=NS(=O)(=O)N1C)c2ccc(OC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J02 compound treatment 0.641 0.393 4.12 0.574 0.343 4.1 5.8148 1.0 3043420 ChemDiv3_016040 CC(C)N(Cc1ccccc1)C(=O)Cc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J03 compound treatment 0.305 0.0565 0.59 0.3 0.0688 0.82 1.0015 0.9872 3043421 ChemDiv3_016041 CCN(CC)C(=O)C1=CC(=NS(=O)(=O)N1C)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J04 compound treatment 0.804 0.556 5.83 0.773 0.542 6.48 8.7089 0.9986 3043423 ChemDiv3_016042 COc1cc(cc(OC)c1OC)c2cc(NC(=O)Cc3noc4ccc(C)cc34)on2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J05 compound treatment 0.218 -0.0305 -0.32 0.235 0.00375 0.04 -0.1946 -0.6021 3043424 ChemDiv3_016043 CC(C)CNC(=O)C1=CC(=NS(=O)(=O)N1C)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J06 compound treatment 0.462 0.214 2.24 0.367 0.136 1.62 2.7343 0.9874 3043425 ChemDiv3_016044 Cc1ccc(Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J07 compound treatment 0.507 0.259 2.72 0.455 0.224 2.68 3.8129 1.0 3123925 ChemDiv3_016045 O=C(NCC1(CCCC1)c2ccccc2)c3noc-4c3COc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J08 compound treatment 0.209 -0.0395 -0.41 0.172 -0.0592 -0.71 -0.7944 -0.9673 3123926 ChemDiv3_016046 O=C(Cn1ccn(c2ccccc2)c(=O)c1=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J09 compound treatment 0.372 0.124 1.3 0.312 0.0808 0.97 1.6006 0.9895 3043427 ChemDiv3_016047 Cn1nc(C(=O)NC2CCCc3ccccc23)c4CSc5ccccc5-c41 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J10 compound treatment 0.249 5.31E-4 0.01 0.243 0.0118 0.14 0.1034 0.7346 3123927 ChemDiv3_016048 CCC(C)NC(=O)c1cccc2C(=O)CCSc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J11 compound treatment 0.318 0.0695 0.73 0.227 -0.00425 -0.05 0.4804 0.6563 3123928 ChemDiv3_016049 COc1cccc(c1)C(=O)Nc2nn3c(nnc3s2)c4ccc(OC)c(OC)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J12 compound treatment 0.236 -0.0125 -0.13 0.166 -0.0653 -0.78 -0.6446 -0.8143 3043430 ChemDiv3_016050 CC(C)CCNC(=O)c1cccc2C(=O)CCSc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J13 compound treatment 0.466 0.218 2.28 0.428 0.197 2.35 3.28 0.9999 3123929 ChemDiv3_016051 CN(Cc1ccco1)C(=O)c2cc([nH]c2C)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J14 compound treatment 0.129 -0.119 -1.25 0.098 -0.133 -1.59 -2.0145 -0.993 3043432 ChemDiv3_016052 CC1CCCN(CCCNC(=O)c2nc(no2)c3cccnc3)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J15 compound treatment 0.283 0.0345 0.36 0.233 0.00175 0.02 0.2713 0.7467 3123930 ChemDiv3_016053 CCC(Sc1nc2nccnc2c(=O)n1Cc3ccc4OCOc4c3)C(=O)NC5CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J16 compound treatment 1.237 0.989 10.38 1.202 0.971 11.61 15.554 0.9984 3124045 ChemDiv3_016054 CCOC(=O)c1ccc(NC(=O)N2CC(C)Oc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J17 compound treatment 0.312 0.0635 0.67 0.307 0.0757 0.91 1.1127 0.9887 3043434 ChemDiv3_016055 Cn1cc(cc1C(=O)N2CCC(Cc3ccccc3)CC2)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J18 compound treatment 1.289 1.04 10.93 1.286 1.05 12.62 16.6508 0.9974 3124046 ChemDiv3_016056 CNC(=O)CCCc1cn(Cc2ccc(C)cc2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J19 compound treatment 0.258 0.00953 0.1 0.241 0.00975 0.12 0.1533 0.9971 3043436 ChemDiv3_016057 CC1CCCC(C1C)N(C)S(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J20 compound treatment 0.338 0.0895 0.94 0.306 0.0747 0.89 1.2973 0.9997 3124047 ChemDiv3_016058 COc1ccc(CCNC(=O)c2cc(no2)c3ccccc3O)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J21 compound treatment 0.437 0.189 1.98 0.433 0.202 2.41 3.107 0.9952 3124048 ChemDiv3_016059 CCN(C(=O)Cc1noc2ccccc12)c3cc(C)ccc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J22 compound treatment 0.288 0.0395 0.42 0.222 -0.00925 -0.11 0.2153 0.5011 3043438 ChemDiv3_016060 CCN(Cc1ccccc1)S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J23 mock treatment 0.258 0.00953 0.1 0.221 -0.0103 -0.12 -0.0159 -0.1006 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 J24 mock treatment 0.232 -0.0165 -0.17 0.218 -0.0133 -0.16 -0.2344 -0.9991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K01 compound treatment 0.334 0.0855 0.9 0.264 0.0328 0.39 0.9123 0.9308 3124049 ChemDiv3_016061 O=C(NCc1nc(no1)c2ccccc2)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K02 compound treatment 0.184 -0.0645 -0.68 0.184 -0.0473 -0.57 -0.8785 -0.996 3043498 ChemDiv3_016062 CC1CC(C)CN(C1)c2nnc(NC(=O)Nc3cc(C)cc(C)c3)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K03 compound treatment 0.346 0.0975 1.02 0.339 0.108 1.29 1.6359 0.9935 3043499 ChemDiv3_016063 CC(C)(C)CC(=O)NCc1nc(no1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K04 compound treatment 0.189 -0.0595 -0.62 0.174 -0.0573 -0.68 -0.926 -0.9989 3043501 ChemDiv3_016064 Clc1ccc2cnn(CC(=O)NC3CCCC3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K05 compound treatment 0.216 -0.0325 -0.34 0.177 -0.0543 -0.65 -0.7001 -0.9548 3043503 ChemDiv3_016065 Cc1ccc(NC(=O)N2CCC(O)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K06 compound treatment 0.594 0.346 3.63 0.561 0.33 3.95 5.3558 0.9991 3043504 ChemDiv3_016066 CCOC(=O)C1CCCN(C1)C(=O)CCCC(=O)n2ncc3cc(C)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K07 compound treatment 0.795 0.547 5.74 0.694 0.463 5.54 7.9737 0.9998 3043506 ChemDiv3_016067 O=c1cc(nc2scc(c3ccccc3)n12)N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K08 compound treatment 0.1 -0.148 -1.56 0.083 -0.148 -1.77 -2.3568 -0.9979 3043507 ChemDiv3_016068 CCCC1N(CCn2c(C)ccc12)C(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K09 compound treatment 0.097 -0.151 -1.59 0.094 -0.137 -1.64 -2.286 -0.9999 3124050 ChemDiv3_016069 CCC(Oc1ccccc1)c2nc3ccccc3n2CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K10 compound treatment 0.73 0.482 5.06 0.676 0.445 5.32 7.3387 0.9997 3124051 ChemDiv3_016070 CCc1ccc(CN(Cc2c[nH]nc2c3ccc(OC)cc3)C(=O)Nc4ccc(C)cc4C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K11 compound treatment 0.354 0.106 1.11 0.308 0.0767 0.92 1.433 0.9956 3043508 ChemDiv3_016071 Cc1ccc(cc1)c2nccnn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K12 compound treatment 0.268 0.0195 0.21 0.245 0.0138 0.16 0.2614 0.994 3043510 ChemDiv3_016072 CCCCN(CC)C(=O)Nc1ccc2Sc3ccccc3C(=O)N(CC)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K13 compound treatment 0.397 0.149 1.56 0.315 0.0838 1.0 1.8116 0.9771 3124052 ChemDiv3_016073 CN(C)C(=O)CCCc1nc(no1)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K14 compound treatment 0.416 0.168 1.76 0.404 0.173 2.07 2.7057 0.9968 3043512 ChemDiv3_016074 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K15 compound treatment 0.471 0.223 2.34 0.407 0.176 2.1 3.1395 0.9986 3124053 ChemDiv3_016075 C(Nc1cc(nc2nncn12)c3ccccc3)C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K16 compound treatment 0.301 0.0525 0.55 0.282 0.0508 0.61 0.8195 0.9989 3124054 ChemDiv3_016076 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)NCCCN4CCN(CC4)c5cc(C)ccc5C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K17 compound treatment 1.332 1.08 11.38 1.3 1.07 12.79 17.0886 0.9983 3043515 ChemDiv3_016077 Clc1cccc(c1)n2nnc(n2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K18 compound treatment 0.256 0.00753 0.08 0.208 -0.0233 -0.28 -0.1408 -0.4867 3124055 ChemDiv3_016078 CC1CN(C(=O)CCC(=O)NC2CCCC2)c3ccccc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K19 compound treatment 0.093 -0.155 -1.63 0.091 -0.14 -1.68 -2.3411 -0.9999 3043517 ChemDiv3_016079 C(Nc1c2CCCc2nc3nncn13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K20 compound treatment 0.3 0.0515 0.54 0.274 0.0428 0.51 0.7444 0.9996 3124056 ChemDiv3_016080 O=C(C1CCCN1c2nnc(s2)N3CCCC3=O)N4CCN(CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K21 compound treatment 0.298 0.0495 0.52 0.284 0.0527 0.63 0.8141 0.9954 3043519 ChemDiv3_016081 COc1ccc(cc1)c2noc(CNC(=O)Nc3cccc(C)c3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K22 compound treatment 0.221 -0.0275 -0.29 0.197 -0.0343 -0.41 -0.4938 -0.9852 3124057 ChemDiv3_016082 CC(C)NC(=O)C(C)n1ncn2cccc2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K23 mock treatment 0.197 -0.0515 -0.54 0.178 -0.0532 -0.64 -0.8327 -0.9967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 K24 mock treatment 0.254 0.00553 0.06 0.235 0.00375 0.04 0.0728 0.9918 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L01 compound treatment 0.219 -0.0295 -0.31 0.221 -0.0103 -0.12 -0.3056 -0.9179 3043521 ChemDiv3_016083 COc1ccc(cc1)C2=NS(=O)(=O)N(C)C(=C2)C(=O)NCC=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L02 compound treatment 0.348 0.0995 1.05 0.332 0.101 1.21 1.5915 0.9975 3124058 ChemDiv3_016084 CCOc1ccc(CCNC(=O)Cc2noc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L03 compound treatment 0.363 0.115 1.2 0.336 0.105 1.25 1.7368 0.9998 3124059 ChemDiv3_016085 COc1ccc(cc1OC)C2=NS(=O)(=O)N(C)C(=C2)C(=O)N3CCC(C)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L04 compound treatment 0.138 -0.11 -1.16 0.137 -0.0943 -1.13 -1.6178 -0.9999 3043523 ChemDiv3_016086 CCN1CCCC1CNC(=O)c2nnc(Cc3cccc(F)c3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L05 compound treatment 0.553 0.305 3.2 0.502 0.271 3.24 4.5522 1.0 3124060 ChemDiv3_016087 CC1CCCCN1C(=O)Cn2nc(NC(=O)C3=CC(=NS(=O)(=O)N3C)c4ccc(C)cc4)cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L06 compound treatment 0.257 0.00853 0.09 0.212 -0.0193 -0.23 -0.0995 -0.4026 3043526 ChemDiv3_016088 Clc1ccc(Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L07 compound treatment 0.213 -0.0355 -0.37 0.192 -0.0393 -0.47 -0.5955 -0.9934 3042437 ChemDiv3_016089 CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2noc-3c2COc4ccccc34)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L08 compound treatment 0.109 -0.139 -1.46 0.104 -0.127 -1.52 -2.1123 -0.9998 3042439 ChemDiv3_016090 CCc1ccc(NC(=O)c2n[nH]c-3c2CSc4ccccc34)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L09 compound treatment 0.165 -0.0835 -0.88 0.149 -0.0823 -0.98 -1.3157 -0.9983 3042440 ChemDiv3_016091 Cn1nc(C(=O)Nc2cccnc2)c3CSc4ccccc4-c31 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L10 compound treatment 0.236 -0.0125 -0.13 0.175 -0.0563 -0.67 -0.5685 -0.8291 3042441 ChemDiv3_016092 CC1CCCCN1C(=O)c2cccc3C(=O)CCSc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L11 compound treatment 0.222 -0.0265 -0.28 0.203 -0.0283 -0.34 -0.4356 -0.9953 3042443 ChemDiv3_016093 COc1cccc(c1)C(=O)Nc2nn3c(COc4ccccc4)nnc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L12 compound treatment 0.179 -0.0695 -0.73 0.142 -0.0892 -1.07 -1.271 -0.9828 3042444 ChemDiv3_016094 Cc1ccc(CCNC(=O)c2cccc3C(=O)CCSc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L13 compound treatment 0.303 0.0545 0.57 0.216 -0.0153 -0.18 0.276 0.4591 3124061 ChemDiv3_016095 Cc1[nH]c(cc1C(=O)NCCCN2CCN(CC2)C3CCCCC3)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L14 compound treatment 0.219 -0.0295 -0.31 0.169 -0.0623 -0.74 -0.7455 -0.9243 3042446 ChemDiv3_016096 CN1CCN(CCNC(=O)c2nc(no2)c3cccnc3)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L15 compound treatment 0.045 -0.203 -2.14 0.043 -0.188 -2.25 -3.1037 -0.9997 3124062 ChemDiv3_016097 COc1ccc(Cl)cc1NC(=O)CSc2nc3nccnc3c(=O)n2Cc4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L16 compound treatment 0.646 0.398 4.18 0.646 0.415 4.96 6.4611 0.9963 3042448 ChemDiv3_016098 CC1CN(C(=O)Nc2ccccc2)c3cc(C)ccc3O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L17 compound treatment 0.3 0.0515 0.54 0.259 0.0278 0.33 0.6175 0.9725 3124063 ChemDiv3_016099 CC(C)c1ccc(NC(=O)c2cc(cn2C)S(=O)(=O)N3CCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L18 compound treatment 1.417 1.17 12.27 1.438 1.21 14.44 18.8874 0.9967 3042450 ChemDiv3_016100 CNC(=O)CCCc1cn(Cc2ccccc2Cl)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L19 compound treatment 0.696 0.448 4.7 0.641 0.41 4.9 6.7901 0.9998 3124064 ChemDiv3_016101 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)Nc4cccc(OC)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L20 compound treatment 0.681 0.433 4.54 0.654 0.423 5.06 6.7887 0.9986 3124065 ChemDiv3_016102 Oc1ccccc1c2cc(on2)C(=O)NCc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L21 compound treatment 0.349 0.101 1.06 0.331 0.0998 1.19 1.5905 0.9981 3042453 ChemDiv3_016103 CCN(C(=O)Cc1noc2ccccc12)c3cc(OC)ccc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L22 compound treatment 0.207 -0.0415 -0.44 0.215 -0.0163 -0.19 -0.4454 -0.9339 3124066 ChemDiv3_016104 OC(=O)c1cc(c2cccc(O)c2)c3c(n[nH]c3n1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L23 mock treatment 0.242 -0.00647 -0.07 0.185 -0.0462 -0.55 -0.4393 -0.788 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 L24 mock treatment 0.219 -0.0295 -0.31 0.182 -0.0493 -0.59 -0.6355 -0.9548 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M01 compound treatment 0.508 0.26 2.73 0.472 0.241 2.88 3.9642 0.9996 3042455 ChemDiv3_016105 O=C(Cc1ccccc1)NCc2nc(no2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M02 compound treatment 0.179 -0.0695 -0.73 0.141 -0.0902 -1.08 -1.2794 -0.9818 3124067 ChemDiv3_016106 CCc1ccc(NC(=O)Nc2nnc(s2)N(C)Cc3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M03 compound treatment 0.518 0.27 2.83 0.45 0.219 2.62 3.8523 0.9992 3124068 ChemDiv3_016107 O=C(CC(c1ccccc1)c2ccccc2)NCc3nc(no3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M04 compound treatment 0.168 -0.0805 -0.85 0.158 -0.0732 -0.88 -1.2173 -0.9998 3042457 ChemDiv3_016108 CC1CCCCN1CCCNC(=O)Cn2ncc3ccc(Cl)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M05 compound treatment 0.291 0.0425 0.45 0.26 0.0288 0.34 0.5591 0.9917 3124069 ChemDiv3_016109 CC1CCN(CC1)c2nc(Cc3ccc(Cl)cc3Cl)nc4n(C)nnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M06 compound treatment 0.184 -0.0645 -0.68 0.163 -0.0683 -0.82 -1.0562 -0.9957 3042459 ChemDiv3_016110 O=C(CCC(=O)n1ncc2ccccc12)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M07 compound treatment 0.088 -0.16 -1.69 0.087 -0.144 -1.73 -2.4121 -0.9999 3124070 ChemDiv3_016111 CC(C)Cn1c(nc2ccccc12)C(O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M08 compound treatment 0.701 0.453 4.75 0.718 0.487 5.82 7.4787 0.9949 3124071 ChemDiv3_016112 CCCC1N(CCn2c(C)ccc12)C(=O)Nc3cc(Cl)ccc3C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M09 compound treatment 0.338 0.0895 0.94 0.264 0.0328 0.39 0.942 0.9247 3042461 ChemDiv3_016113 C=CCc1ccccc1OCc2nc3ccccc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M10 compound treatment 0.119 -0.129 -1.36 0.106 -0.125 -1.5 -2.0211 -0.9988 3124072 ChemDiv3_016114 CC1CCCN(C1)c2nnc(NC(=O)NCc3ccc(C)cc3)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M11 compound treatment 0.884 0.636 6.67 0.847 0.616 7.37 9.9291 0.9988 3042529 ChemDiv3_016115 Clc1ccc(cc1)c2cnnc(n2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M12 compound treatment 0.455 0.207 2.17 0.416 0.185 2.21 3.0968 1.0 3124182 ChemDiv3_016116 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)N4CCCCC4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M13 compound treatment 0.386 0.138 1.44 0.405 0.174 2.08 2.4913 0.9842 3043363 ChemDiv3_016117 COC(=O)c1ccccc1NC(=O)Cn2c(CCC(=O)O)ccc2c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M14 compound treatment 0.511 0.263 2.76 0.498 0.267 3.19 4.2064 0.9973 3043365 ChemDiv3_016118 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NC4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M15 compound treatment 0.41 0.162 1.7 0.374 0.143 1.71 2.4073 1.0 3043366 ChemDiv3_016119 C=CCNc1cc(nc2nncn12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M16 compound treatment 0.396 0.148 1.55 0.381 0.15 1.79 2.3625 0.9974 3043368 ChemDiv3_016120 CC1CCCC(NC2=NS(=O)(=O)C(=C2C)c3ccc(C)cc3)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M17 compound treatment 0.508 0.26 2.73 0.472 0.241 2.88 3.9642 0.9996 3043369 ChemDiv3_016121 c1ccc(cc1)c2nnn(n2)c3cnc4ccccc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M18 compound treatment 0.235 -0.0135 -0.14 0.236 0.00475 0.06 -0.0598 -0.3925 3043371 ChemDiv3_016122 O=C(CCC(=O)N1CCOc2ccccc12)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M19 compound treatment 0.271 0.0225 0.24 0.26 0.0288 0.34 0.4106 0.9833 3124183 ChemDiv3_016123 O=c1c2CN(Cc3ccccc3)CCc2[nH]c4nncn14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M20 compound treatment 0.236 -0.0125 -0.13 0.201 -0.0302 -0.36 -0.3485 -0.9055 3043373 ChemDiv3_016124 O=C(NCc1ccccc1)C2CCCN2c3nnc(s3)N4CCCC4=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M21 compound treatment 0.664 0.416 4.36 0.645 0.414 4.95 6.5863 0.998 3124184 ChemDiv3_016125 COc1ccc(cc1)c2noc(CN(C(C)C)C(=O)Nc3cccc(C)c3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M22 compound treatment 0.408 0.16 1.68 0.32 0.0887 1.06 1.9356 0.9758 3124185 ChemDiv3_016126 CC1CCCCN1C(=O)C2=CC(=NS(=O)(=O)N2C)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M23 mock treatment 0.22 -0.0285 -0.3 0.184 -0.0473 -0.57 -0.6112 -0.9557 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 M24 mock treatment 0.228 -0.0205 -0.21 0.235 0.00375 0.04 -0.1203 -0.5477 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N01 compound treatment 0.204 -0.0445 -0.47 0.196 -0.0352 -0.42 -0.6285 -0.9987 3043375 ChemDiv3_016127 CCN1CCN(CC1)C(=O)C2=CC(=NS(=O)(=O)N2C)c3ccc(OC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N02 compound treatment 0.205 -0.0435 -0.46 0.169 -0.0623 -0.74 -0.8495 -0.9724 3124186 ChemDiv3_016128 CCN1CCN(Cc2ccc(NC(=O)Cc3noc4ccccc34)cc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N03 compound treatment 0.213 -0.0355 -0.37 0.203 -0.0283 -0.34 -0.5024 -0.9988 3043377 ChemDiv3_016129 CN1C(=CC(=NS1(=O)=O)c2ccco2)C(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N04 compound treatment 0.757 0.509 5.34 0.63 0.399 4.77 7.1501 0.9984 3124187 ChemDiv3_016130 CCCNC(=O)c1nnc(Cc2ccc(OC)c(OC)c2)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N05 compound treatment 0.215 -0.0335 -0.35 0.212 -0.0193 -0.23 -0.4114 -0.979 3043379 ChemDiv3_016131 COC(=O)c1cc(cn1C)S(=O)(=O)NC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N06 compound treatment 0.239 -0.00947 -0.1 0.243 0.0118 0.14 0.0291 0.1689 3043440 ChemDiv3_016132 NS(=O)(=O)c1ccc(CCn2ccn(CC(=O)NCCC3=CCCCC3)c(=O)c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N07 compound treatment 0.33 0.0815 0.86 0.277 0.0457 0.55 0.9925 0.9766 3043442 ChemDiv3_016133 CSc1cccc(NC(=O)c2noc-3c2CSc4ccccc34)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N08 compound treatment 0.896 0.648 6.8 0.793 0.562 6.72 9.5614 1.0 3043443 ChemDiv3_016134 COc1ccc(NC(=O)c2sc3nc4CCCCCn4c(=O)c3c2C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N09 compound treatment 1.181 0.933 9.79 1.206 0.975 11.66 15.172 0.9962 3043444 ChemDiv3_016135 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3nn(C)c-4c3CSc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N10 compound treatment 0.332 0.0835 0.88 0.366 0.135 1.61 1.7603 0.9591 3043446 ChemDiv3_016136 CC1CCN(CC1)C(=O)c2cccc3C(=O)CCSc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N11 compound treatment 0.238 -0.0105 -0.11 0.173 -0.0583 -0.7 -0.5705 -0.8087 3043447 ChemDiv3_016137 O=C(Cc1ccccc1)Nc2nn3c(COc4ccccc4)nnc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N12 compound treatment 0.14 -0.108 -1.14 0.14 -0.0912 -1.09 -1.5775 -0.9998 3124188 ChemDiv3_016138 CC1CCCCC1NC(=O)c2cccc3C(=O)CCSc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N13 compound treatment 0.288 0.0395 0.42 0.31 0.0788 0.94 0.9598 0.9322 3043450 ChemDiv3_016139 Cc1cccc(Cn2nc(Cc3cccnc3)c4ccccc4c2=O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N14 compound treatment 0.256 0.00753 0.08 0.197 -0.0343 -0.41 -0.2338 -0.5603 3124189 ChemDiv3_016140 O=C(C1CCN(CC1)C(=O)N2CCOc3ccccc23)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N15 compound treatment 0.336 0.0875 0.92 0.302 0.0707 0.85 1.2486 0.9992 3043451 ChemDiv3_016141 CN(c1cccc(C)c1)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N16 compound treatment 0.551 0.303 3.18 0.52 0.289 3.45 4.6896 0.9991 3042463 ChemDiv3_016142 CCOc1ccccc1NC(=O)N2CCOc3ccc(Cl)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N17 compound treatment 0.28 0.0315 0.33 0.251 0.0198 0.24 0.4013 0.9863 3124190 ChemDiv3_016143 CN(C(=O)c1cc(cn1C)S(=O)(=O)N2CCCC2)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N18 compound treatment 0.096 -0.152 -1.6 0.089 -0.142 -1.7 -2.3358 -0.9995 3124191 ChemDiv3_016144 CCN1CCCC1CNC(=O)c2ccc3c(c2)sc4nc(cn43)c5cccc(OC)c5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N19 compound treatment 0.384 0.136 1.42 0.39 0.159 1.9 2.3496 0.9899 3043454 ChemDiv3_016145 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)N(C)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N20 compound treatment 0.23 -0.0185 -0.19 0.235 0.00375 0.04 -0.1054 -0.5296 3124192 ChemDiv3_016146 O=C1COc2cc(ccc2N1)S(=O)(=O)N3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N21 compound treatment 1.071 0.823 8.64 1.003 0.772 9.23 12.6376 0.9994 3043456 ChemDiv3_016147 Clc1ccc(CCNC(=O)Cc2noc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N22 compound treatment 0.171 -0.0775 -0.81 0.19 -0.0413 -0.49 -0.9243 -0.9713 3124193 ChemDiv3_016148 CN1C(C(C(=O)NCCCN2CCCCC2)c3ccccc3C1=O)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N23 mock treatment 0.241 -0.00747 -0.08 0.232 7.5E-4 0.01 -0.0491 -0.6222 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 N24 mock treatment 0.2 -0.0485 -0.51 0.201 -0.0302 -0.36 -0.6159 -0.986 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O01 compound treatment 0.726 0.478 5.02 0.692 0.461 5.51 7.4444 0.9989 3043458 ChemDiv3_016149 COc1ccc(cc1)c2noc(CNC(=O)COc3ccccc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O02 compound treatment 0.392 0.144 1.51 0.362 0.131 1.56 2.1721 0.9998 3124194 ChemDiv3_016150 Cc1ccc2cnn(CCCC(=O)NCc3ccccc3)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O03 compound treatment 0.686 0.438 4.6 0.664 0.433 5.18 6.9105 0.9982 3124195 ChemDiv3_016151 O=C(CCC1CCCC1)NCc2nc(no2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O04 compound treatment 0.158 -0.0905 -0.95 0.136 -0.0953 -1.14 -1.4777 -0.9959 3043460 ChemDiv3_016152 CC1CCCC(NC(=O)Cn2ncc3c(Cl)cccc23)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O05 compound treatment 0.151 -0.0975 -1.02 0.134 -0.0973 -1.16 -1.5466 -0.998 3124196 ChemDiv3_016153 C1CC2CN(CCN2C1)c3ncnc4[nH]cnc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O06 compound treatment 0.607 0.359 3.77 0.581 0.35 4.18 5.6216 0.9986 3124197 ChemDiv3_016154 Cc1ccc2n(ncc2c1)C(=O)CCCC(=O)NC3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O07 compound treatment 0.099 -0.149 -1.57 0.1 -0.131 -1.57 -2.2204 -1.0 1544850 ChemDiv3_016155 CC(C)n1c(nc2ccccc12)C(O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O08 compound treatment 0.154 -0.0945 -0.99 0.146 -0.0853 -1.02 -1.4228 -0.9999 3124198 ChemDiv3_016156 CCCCN(C)c1nnc(NC(=O)Nc2cccc(C)c2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O09 compound treatment 0.2 -0.0485 -0.51 0.191 -0.0403 -0.48 -0.7005 -0.9996 3042464 ChemDiv3_016157 CC(C)n1c(COc2cc(C)ccc2C)nc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O10 compound treatment 0.316 0.0675 0.71 0.316 0.0848 1.01 1.2185 0.9847 3042466 ChemDiv3_016158 Fc1ccc(CN2C(=O)c3ccccc3OC42CCN(CC4)C(=O)NC5CCCC5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O11 compound treatment 0.311 0.0625 0.66 0.292 0.0607 0.73 0.9783 0.9987 3042467 ChemDiv3_016159 O=C(CCCc1nc(no1)c2ccccc2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O12 compound treatment 0.51 0.262 2.75 0.544 0.313 3.74 4.5882 0.9884 3042469 ChemDiv3_016160 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)NCc4ccccc4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O13 compound treatment 0.11 -0.138 -1.45 0.103 -0.128 -1.53 -2.1134 -0.9996 3042470 ChemDiv3_016161 COc1cccc(c1)c2noc(n2)C(C)Oc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O14 compound treatment 0.581 0.333 3.49 0.522 0.291 3.48 4.9293 1.0 3124199 ChemDiv3_016162 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NCc4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O15 compound treatment 0.391 0.143 1.5 0.363 0.132 1.58 2.1731 0.9997 3042472 ChemDiv3_016163 C(Cc1ccccc1)Nc2cc(nc3nncn23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O16 compound treatment 0.295 0.0465 0.49 0.28 0.0488 0.58 0.758 0.9961 3124200 ChemDiv3_016164 CC1CN(CCN1c2cccc(C)c2)C(=O)CCC(=O)N3CCOc4ccc(Cl)cc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O17 compound treatment 1.16 0.912 9.57 1.059 0.828 9.9 13.7724 0.9999 3042474 ChemDiv3_016165 CCc1nonc1NC(=O)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O18 compound treatment 0.35 0.102 1.07 0.294 0.0628 0.75 1.2849 0.9853 3124201 ChemDiv3_016166 Clc1ccccc1NC(=O)CCC(=O)N2CCOc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O19 compound treatment 0.183 -0.0655 -0.69 0.16 -0.0712 -0.85 -1.089 -0.9943 3042476 ChemDiv3_016167 Cc1cc(N2CCCC(C2)C(=O)O)n3cnnc3n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O20 compound treatment 0.227 -0.0215 -0.23 0.231 -2.5E-4 0.0 -0.1616 -0.7164 3124202 ChemDiv3_016168 CCOc1ccc(NC(=O)C2CCCN2c3nnc(s3)N4CCCC4=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O21 compound treatment 0.244 -0.00447 -0.05 0.272 0.0408 0.49 0.3116 0.6361 3042478 ChemDiv3_016169 COc1ccc(cc1OC)c2noc(CN(C(C)C)C(=O)NC3CCCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O22 compound treatment 0.316 0.0675 0.71 0.3 0.0688 0.82 1.0832 0.9973 3124203 ChemDiv3_016170 CN1C(=CC(=NS1(=O)=O)c2ccc(C)cc2)C(=O)N3CCc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O23 mock treatment 0.186 -0.0625 -0.66 0.163 -0.0683 -0.82 -1.0413 -0.9941 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 O24 mock treatment 0.252 0.00353 0.04 0.219 -0.0123 -0.15 -0.0774 -0.512 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P01 compound treatment 0.238 -0.0105 -0.11 0.205 -0.0262 -0.31 -0.2998 -0.901 3124204 ChemDiv3_016171 COc1ccc(cc1)C2=NS(=O)(=O)N(C)C(=C2)C(=O)N3CCC(CC3)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P02 compound treatment 0.285 0.0365 0.38 0.236 0.00475 0.06 0.3115 0.8031 3042480 ChemDiv3_016172 CC(NC(=O)Cc1noc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P03 compound treatment 0.185 -0.0635 -0.67 0.19 -0.0413 -0.49 -0.8203 -0.9891 3124205 ChemDiv3_016173 CC(C)NC(=O)C1=CC(=NS(=O)(=O)N1C)c2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P04 compound treatment 0.371 0.123 1.29 0.298 0.0668 0.8 1.4747 0.9737 3042482 ChemDiv3_016174 COc1ccc(Cc2nnc(o2)C(=O)N3CCN(CC3)c4ccccc4OC)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P05 compound treatment 0.221 -0.0275 -0.29 0.174 -0.0573 -0.68 -0.6883 -0.9261 3124206 ChemDiv3_016175 COC(=O)c1cc(cn1C)S(=O)(=O)NC2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P06 compound treatment 0.188 -0.0605 -0.64 0.171 -0.0602 -0.72 -0.9588 -0.998 3124207 ChemDiv3_016176 Cc1ccc(CNC(=O)Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P07 compound treatment 0.206 -0.0425 -0.45 0.232 7.5E-4 0.01 -0.309 -0.6927 3042484 ChemDiv3_016177 Cc1cccc(CCNC(=O)c2nn(C)c-3c2COc4ccccc34)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P08 compound treatment 0.146 -0.102 -1.08 0.152 -0.0793 -0.95 -1.4315 -0.998 3124208 ChemDiv3_016178 CN1CCN(CCNC(=O)c2sc3nc4CCCCCn4c(=O)c3c2C)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P09 compound treatment 0.473 0.225 2.36 0.455 0.224 2.68 3.5604 0.998 3042487 ChemDiv3_016179 Cn1nc(C(=O)NCCc2ccsc2)c3CSc4ccccc4-c31 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P10 compound treatment 0.103 -0.145 -1.53 0.1 -0.131 -1.57 -2.1907 -0.9999 3124209 ChemDiv3_016180 CCc1ccc(NC(=O)c2cccc3C(=O)CCSc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P11 compound treatment 0.199 -0.0495 -0.52 0.164 -0.0673 -0.8 -0.9363 -0.9776 3124210 ChemDiv3_016181 O=C(CCc1ccccc1)Nc2nn3c(nnc3s2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P12 compound treatment 0.174 -0.0745 -0.78 0.181 -0.0503 -0.6 -0.9782 -0.9916 3042489 ChemDiv3_016182 O=C(NCc1ccccc1)c2cccc3C(=O)CCSc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P13 compound treatment 0.247 -0.00147 -0.02 0.238 0.00675 0.08 0.0462 0.5619 3042531 ChemDiv3_016183 CCOC(=O)CSc1nc2nccnc2c(=O)n1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P14 compound treatment 0.144 -0.104 -1.1 0.148 -0.0833 -1.0 -1.4801 -0.9988 3042533 ChemDiv3_016184 CNC(=O)C1CCN(CC1)C(=O)N2CCOc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P15 compound treatment 0.235 -0.0135 -0.14 0.223 -0.00825 -0.1 -0.1698 -0.9845 3042534 ChemDiv3_016185 CN1CCOc2cc(ccc12)S(=O)(=O)NCCc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P16 compound treatment 1.3 1.05 11.04 1.4 1.17 13.98 17.697 0.9932 3042536 ChemDiv3_016186 Cc1cccc(NC(=O)N2CCOc3ccc(Cl)cc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P17 compound treatment 0.166 -0.0825 -0.87 0.161 -0.0703 -0.84 -1.2068 -0.9999 3042537 ChemDiv3_016187 Cn1cc(cc1C(=O)NCc2ccccc2)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P18 compound treatment 0.184 -0.0645 -0.68 0.148 -0.0833 -1.0 -1.1831 -0.9823 3042538 ChemDiv3_016188 COc1ccc(cc1OC)c2cc(on2)C(=O)NC(C)(C)CO 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P19 compound treatment 0.213 -0.0355 -0.37 0.205 -0.0262 -0.31 -0.4855 -0.9964 3042540 ChemDiv3_016189 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)NCc4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P20 compound treatment 0.168 -0.0805 -0.85 0.149 -0.0823 -0.98 -1.2934 -0.9971 3042541 ChemDiv3_016190 O=C1COc2cc(ccc2N1)S(=O)(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P21 compound treatment 0.676 0.428 4.49 0.659 0.428 5.12 6.7939 0.9979 3124324 ChemDiv3_016191 CCc1cccc(NC(=O)Cc2noc3ccccc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P22 compound treatment 0.178 -0.0705 -0.74 0.204 -0.0273 -0.33 -0.7539 -0.9322 3124325 ChemDiv3_016192 CCC(C)NC(=O)C1C(N(CCOC)C(=O)c2ccccc12)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P23 mock treatment 0.19 -0.0585 -0.61 0.204 -0.0273 -0.33 -0.6648 -0.9561 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2046 P24 mock treatment 0.196 -0.0525 -0.55 0.182 -0.0493 -0.59 -0.8063 -0.9994 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A01 compound treatment 0.254 0.0369 0.39 0.223 -0.00772 -0.09 0.209 0.5241 3124326 ChemDiv3_016193 COCCN1C(C(C(=O)NCC2CCCO2)c3ccccc3C1=O)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A02 compound treatment 0.261 0.0439 0.46 0.232 0.00128 0.02 0.3371 0.7302 3042544 ChemDiv3_016194 O=C(CCn1c(=O)c2cccn2c3cccnc13)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A03 compound treatment 0.326 0.109 1.14 0.338 0.107 1.28 1.7166 0.9984 3042545 ChemDiv3_016195 COc1cccc(c1)n2cc(C(=O)N(C)c3ccccc3)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A04 compound treatment 0.323 0.106 1.11 0.317 0.0863 1.03 1.5167 0.9993 3124327 ChemDiv3_016196 CCc1ccccc1NC(=O)CCC(=O)N2CCSc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A05 compound treatment 0.238 0.0209 0.22 0.266 0.0353 0.42 0.454 0.9538 3124328 ChemDiv3_016197 Cc1cccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A06 compound treatment 0.342 0.125 1.31 0.308 0.0773 0.92 1.5817 0.9853 3042547 ChemDiv3_016198 CCn1cc(CCC(=O)NC2CCCC(C)C2C)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A07 compound treatment 0.119 -0.0981 -1.03 0.124 -0.107 -1.28 -1.6311 -0.9943 3124329 ChemDiv3_016199 Fc1ccc(NC(=O)Nc2noc-3c2COc4ccccc34)c(F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A08 compound treatment 0.261 0.0439 0.46 0.293 0.0623 0.75 0.8532 0.9735 3042549 ChemDiv3_016200 Fc1ccc(Cn2cc(CCC(=O)N3CCOCC3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A09 compound treatment 0.116 -0.101 -1.06 0.12 -0.111 -1.32 -1.6872 -0.994 3124330 ChemDiv3_016201 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NCCN4CCc5ccccc5C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A10 compound treatment 0.218 9.38E-4 0.01 0.232 0.00128 0.02 0.0178 0.9771 3124331 ChemDiv3_016202 COc1ccc(cc1)c2noc(CC(=O)N3CCC(C)CC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A11 compound treatment 0.201 -0.0161 -0.17 0.222 -0.00872 -0.1 -0.1931 -0.9733 3042552 ChemDiv3_016203 Cc1cc2NC(=O)COc2cc1S(=O)(=O)CCC(=O)NCc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A12 compound treatment 0.128 -0.0891 -0.94 0.134 -0.0967 -1.16 -1.4797 -0.9944 3124332 ChemDiv3_016204 Cc1nc2ccc(cc2s1)S(=O)(=O)CCC(=O)N3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A13 compound treatment 0.225 0.00794 0.08 0.206 -0.0247 -0.3 -0.1502 -0.4887 3124333 ChemDiv3_016205 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)CCC(=O)N(C)c3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A14 compound treatment 0.298 0.0809 0.85 0.271 0.0403 0.48 0.9419 0.9639 3042554 ChemDiv3_016206 CN(C1CCCCC1)S(=O)(=O)c2c(C)nc3sccn3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A15 compound treatment 0.256 0.0389 0.41 0.315 0.0843 1.01 1.0022 0.921 3042555 ChemDiv3_016207 CCN(c1cccc(C)c1)S(=O)(=O)c2c[nH]c(c2)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A16 compound treatment 0.277 0.0599 0.63 0.259 0.0283 0.34 0.6844 0.9576 3042595 ChemDiv3_016208 O=C(NCc1noc2ccccc12)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A17 compound treatment 0.269 0.0519 0.55 0.274 0.0433 0.52 0.7519 0.9997 3042596 ChemDiv3_016209 Cc1ccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A18 compound treatment 0.322 0.105 1.1 0.297 0.0663 0.79 1.3401 0.987 3042598 ChemDiv3_016210 O=C(NCc1noc2ccccc12)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A19 compound treatment 0.349 0.132 1.39 0.293 0.0623 0.75 1.5067 0.9577 3042600 ChemDiv3_016211 O=C(NCCCc1ccccc1)C2CCCN(C2)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A20 compound treatment 0.368 0.151 1.59 0.331 0.1 1.2 1.9693 0.9906 3042601 ChemDiv3_016212 CCc1cccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc4N(C(C)Cc4c3)C(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A21 compound treatment 1.003 0.786 8.25 1.032 0.801 9.59 12.6157 0.9972 3042603 ChemDiv3_016213 Cc1c(oc2ccc3OC(C)(C)CC(=O)c3c12)C(=O)Nc4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A22 compound treatment 0.323 0.106 1.11 0.327 0.0963 1.15 1.6013 0.9998 3124334 ChemDiv3_016214 CC1CCN(CC1)S(=O)(=O)c2ccc3N(CC(=O)Nc4nc(C)cs4)C(=O)COc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A23 mock treatment 0.217 -6.25E-5 0.0 0.213 -0.0177 -0.21 -0.1504 -0.7093 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 A24 mock treatment 0.288 0.0709 0.75 0.271 0.0403 0.48 0.8676 0.9778 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B01 compound treatment 0.242 0.0249 0.26 0.245 0.0143 0.17 0.306 0.9786 3124335 ChemDiv3_016215 Cc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B02 compound treatment 0.221 0.00394 0.04 0.239 0.00828 0.1 0.0993 0.9249 3042605 ChemDiv3_016216 Cc1cc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B03 compound treatment 0.264 0.0469 0.49 0.241 0.0103 0.12 0.4356 0.8573 3124336 ChemDiv3_016217 CC(C)CCn1c(=O)c2sccc2n3c(CCCC(=O)N4CCCC4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B04 compound treatment 0.174 -0.0431 -0.45 0.163 -0.0677 -0.81 -0.8927 -0.9621 3042607 ChemDiv3_016218 Cn1cc(NC(=O)NCCc2ccsc2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B05 compound treatment 0.273 0.0559 0.59 0.31 0.0793 0.95 1.0862 0.9735 3124337 ChemDiv3_016219 CCn1cc(c(=O)c2cc(F)c(cc12)N3CCOCC3)S(=O)(=O)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B06 compound treatment 0.126 -0.0911 -0.96 0.116 -0.115 -1.37 -1.6468 -0.9844 3042609 ChemDiv3_016220 Clc1ccc(CC(=O)Nc2ccc(cc2)c3nnc4CCCCCn34)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B07 compound treatment 0.112 -0.105 -1.1 0.106 -0.125 -1.49 -1.8354 -0.989 3124338 ChemDiv3_016221 CCCNC(=O)C1CCCN(C1)c2nn3cc(nc3s2)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B08 compound treatment 0.17 -0.0471 -0.49 0.19 -0.0407 -0.49 -0.694 -1.0 3124339 ChemDiv3_016222 CN(C(=O)CCS(=O)(=O)c1ccc2N(CCc2c1)C(=O)C)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B09 compound treatment 0.109 -0.108 -1.13 0.108 -0.123 -1.47 -1.8407 -0.9919 3042612 ChemDiv3_016223 CCOC(=O)c1cccc(NC(=O)N2CCC(CN3CCCCC3)CC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B10 compound treatment 0.213 -0.00406 -0.04 0.216 -0.0147 -0.18 -0.1547 -0.8537 3124340 ChemDiv3_016224 CN(C1CCCCC1)C(=O)c2nc(c3ccc(Cl)cc3)n4CCCCCc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B11 compound treatment 0.075 -0.142 -1.49 0.097 -0.134 -1.6 -2.1863 -0.9994 3042613 ChemDiv3_016225 COc1cc(OC)c(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B12 compound treatment 0.153 -0.0641 -0.67 0.144 -0.0867 -1.04 -1.2094 -0.978 3124341 ChemDiv3_016226 Clc1ccccc1CNC(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B13 compound treatment 0.206 -0.0111 -0.12 0.225 -0.00572 -0.07 -0.1305 -0.9681 3124342 ChemDiv3_016227 CCN1CCC(CC1)N(Cc2cccc(OC)c2)C(=O)Nc3ccc(CC)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B14 compound treatment 0.135 -0.0821 -0.86 0.152 -0.0787 -0.94 -1.2754 -0.999 3042616 ChemDiv3_016228 CCc1ccc(NC(=O)c2cnc(SC)nc2C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B15 compound treatment 0.273 0.0559 0.59 0.295 0.0643 0.77 0.9592 0.9912 3042663 ChemDiv3_016229 CCN(Cc1ccccc1)C(=O)Cn2c(SCc3ccc(F)cc3)nc4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B16 compound treatment 0.197 -0.0201 -0.21 0.179 -0.0517 -0.62 -0.5865 -0.8973 3042665 ChemDiv3_016230 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B17 compound treatment 0.209 -0.00806 -0.08 0.56 0.329 3.94 2.7259 0.6917 3042666 ChemDiv3_016231 Cc1ccc2Oc3ncccc3C(=O)N(CC(=O)N4CCOCC4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B18 compound treatment 0.254 0.0369 0.39 0.272 0.0413 0.49 0.6236 0.9929 3042668 ChemDiv3_016232 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)NCc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B19 compound treatment 0.268 0.0509 0.53 0.26 0.0293 0.35 0.626 0.9789 3042669 ChemDiv3_016233 O=S(=O)(N1CCCc2ccccc12)c3ccc4[nH]c5CCCCc5c4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B20 compound treatment 0.325 0.108 1.13 0.363 0.132 1.58 1.9207 0.9866 3042671 ChemDiv3_016234 O=C1N(CCc2ccc(cc2)S(=O)(=O)NCCc3ccccc3)C(=O)c4ncccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B21 compound treatment 0.271 0.0539 0.57 0.284 0.0533 0.64 0.8513 0.9983 3124343 ChemDiv3_016235 CSc1cccc(NC(=O)CC(C)S(=O)(=O)c2ccc3NC(=O)COc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B22 compound treatment 0.203 -0.0141 -0.15 0.275 0.0443 0.53 0.2702 0.4913 3042672 ChemDiv3_016236 O=C1N(Cc2ccc(cc2)S(=O)(=O)N3CCCCC3)C(=O)c4ncccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B23 mock treatment 0.256 0.0389 0.41 0.229 -0.00172 -0.02 0.2746 0.6707 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 B24 mock treatment 0.265 0.0479 0.5 0.237 0.00628 0.08 0.4091 0.8037 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C01 compound treatment 0.187 -0.0301 -0.32 0.202 -0.0287 -0.34 -0.4662 -0.9991 3124344 ChemDiv3_016237 COCCN1C(C(C(=O)Nc2ccc(cc2)C(=O)OC)c3ccccc3C1=O)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C02 compound treatment 0.201 -0.0161 -0.17 0.19 -0.0407 -0.49 -0.4638 -0.8996 3042674 ChemDiv3_016238 O=C(CCn1c(=O)c2cccn2c3cccnc13)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C03 compound treatment 0.517 0.3 3.15 0.484 0.253 3.03 4.3703 0.9998 3124345 ChemDiv3_016239 CCOc1ccccc1CNC(=O)c2cn(c3cccc(OC)c3)c(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C04 compound treatment 0.178 -0.0391 -0.41 0.189 -0.0417 -0.5 -0.643 -0.9953 3124346 ChemDiv3_016240 O=C(CCC(=O)N1CCSc2ccccc12)NCC3CCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C05 compound treatment 0.209 -0.00806 -0.08 0.249 0.0183 0.22 0.0948 0.4041 3042677 ChemDiv3_016241 CC(=O)N1CCSc2cc(ccc12)S(=O)(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C06 compound treatment 0.523 0.306 3.21 0.572 0.341 4.08 5.1593 0.993 3124347 ChemDiv3_016242 CCOc1ccccc1CNC(=O)CCc2cn(CC)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C07 compound treatment 0.202 -0.0151 -0.16 0.247 0.0163 0.19 0.0259 0.1031 3042679 ChemDiv3_016243 COc1ccccc1CNC(=O)Nc2noc-3c2COc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C08 compound treatment 0.19 -0.0271 -0.28 0.167 -0.0637 -0.76 -0.74 -0.9096 3124348 ChemDiv3_016244 Fc1ccc(Cn2cc(CCC(=O)NC3CCCC3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C09 compound treatment 0.069 -0.148 -1.56 0.067 -0.164 -1.96 -2.4847 -0.9935 3124349 ChemDiv3_016245 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3noc-4c3COc5ccc(C)cc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C10 compound treatment 0.244 0.0269 0.28 0.266 0.0353 0.42 0.4985 0.9811 3042682 ChemDiv3_016246 CCN(CC)C(=O)Cc1nc(no1)c2ccc(OC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C11 compound treatment 0.183 -0.0341 -0.36 0.215 -0.0157 -0.19 -0.3859 -0.9549 3124459 ChemDiv3_016247 Clc1ccccc1CNC(=O)CCS(=O)(=O)c2ccc3NC(=O)COc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C12 compound treatment 0.161 -0.0561 -0.59 0.19 -0.0407 -0.49 -0.7608 -0.9956 3042683 ChemDiv3_016248 CSc1cccc(NC(=O)CCS(=O)(=O)c2ccc3nc(C)sc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C13 compound treatment 0.18 -0.0371 -0.39 0.2 -0.0307 -0.37 -0.5351 -0.9996 3124460 ChemDiv3_016249 COC(=O)c1cc(c[nH]1)S(=O)(=O)Nc2ccc(OC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C14 compound treatment 0.275 0.0579 0.61 0.308 0.0773 0.92 1.0841 0.9794 3042685 ChemDiv3_016250 Cc1nc2sccn2c(=O)c1S(=O)(=O)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C15 compound treatment 0.267 0.0499 0.52 0.274 0.0433 0.52 0.737 1.0 3124461 ChemDiv3_016251 COC(=O)c1cc(c[nH]1)S(=O)(=O)N(C)C2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C16 compound treatment 0.24 0.0229 0.24 0.287 0.0563 0.67 0.6465 0.904 3042687 ChemDiv3_016252 CN(C(=O)NCc1noc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C17 compound treatment 0.183 -0.0341 -0.36 0.216 -0.0147 -0.18 -0.3775 -0.9467 3124462 ChemDiv3_016253 CN(CC(=O)NCc1ccccc1)S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C18 compound treatment 0.176 -0.0411 -0.43 0.165 -0.0657 -0.79 -0.8609 -0.96 3124463 ChemDiv3_016254 Cc1nn(c2ccc(C)cc2)c3nc(cc(C)c13)C(=O)NCc4ccc(CN5CCOCC5)o4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C19 compound treatment 0.235 0.0179 0.19 0.281 0.0503 0.6 0.5586 0.8861 3124464 ChemDiv3_016255 COc1ccc2c(CNCC3CCCO3)c(C(=O)O)n(Cc4ccc(C)cc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C20 compound treatment 0.234 0.0169 0.18 0.261 0.0303 0.36 0.382 0.9464 3043406 ChemDiv3_016256 CC(C)C(NS(=O)(=O)c1ccc2N(C(C)Cc2c1)C(=O)C)C(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C21 compound treatment 0.183 -0.0341 -0.36 0.195 -0.0357 -0.43 -0.5552 -0.9961 3124465 ChemDiv3_016257 O=C(CN1C(=O)C(Oc2cccnc12)c3ccccc3)NCCCN4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C22 compound treatment 0.329 0.112 1.18 0.416 0.185 2.22 2.3988 0.956 3043410 ChemDiv3_016258 CC1CCN(CC1)S(=O)(=O)c2ccc3N(CC(=O)NCc4ccc(C)cc4)C(=O)COc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C23 mock treatment 0.227 0.00994 0.1 0.237 0.00628 0.08 0.1269 0.987 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 C24 mock treatment 0.286 0.0689 0.72 0.288 0.0573 0.69 0.9966 0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D01 compound treatment 0.165 -0.0521 -0.55 0.185 -0.0457 -0.55 -0.7734 -1.0 3124466 ChemDiv3_016259 CCCNC(=O)CCc1nnc2ccc(nn12)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D02 compound treatment 0.214 -0.00306 -0.03 0.228 -0.00272 -0.03 -0.0457 -1.0 3043478 ChemDiv3_016260 Cn1cc(NC(=O)Nc2ccccc2F)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D03 compound treatment 0.312 0.0949 1.0 0.35 0.119 1.43 1.7142 0.9846 3124467 ChemDiv3_016261 COc1ccc(cc1)c2noc(n2)N3CCCC(C3)C(=O)NCCc4ccc(OC)c(OC)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D04 compound treatment 0.093 -0.124 -1.3 0.079 -0.152 -1.82 -2.2049 -0.9868 3043482 ChemDiv3_016262 CC1CCN(Cc2ccc(NC(=O)Nc3cn(C)c(=O)c4ccccc34)cc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D05 compound treatment 0.175 -0.0421 -0.44 0.207 -0.0237 -0.28 -0.513 -0.9771 3124468 ChemDiv3_016263 CCCn1cc(c(=O)c2cc(F)c(cc12)N3CCN(CC)CC3)S(=O)(=O)c4ccc(C)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D06 compound treatment 0.099 -0.118 -1.24 0.093 -0.138 -1.65 -2.0419 -0.9902 3043488 ChemDiv3_016264 O=C(CCC1CCCC1)Nc2ccc(cc2)c3nnc4CCCCCn34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D07 compound treatment 0.451 0.234 2.46 0.536 0.305 3.65 4.3201 0.9814 3124469 ChemDiv3_016265 CCC1CN(C(=O)Nc2ccc(CC)cc2)c3ccccc3S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D08 compound treatment 0.229 0.0119 0.13 0.254 0.0233 0.28 0.2856 0.935 3124470 ChemDiv3_016266 CC(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3ccc4NC(=O)C(C)Sc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D09 compound treatment 0.122 -0.0951 -1.0 0.116 -0.115 -1.37 -1.6765 -0.9878 3043493 ChemDiv3_016267 O=C(NCc1ccccc1)N2CCC(CN3CCCCC3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D10 compound treatment 0.171 -0.0461 -0.48 0.195 -0.0357 -0.43 -0.6443 -0.9981 3124471 ChemDiv3_016268 Clc1ccc(cc1)c2nc(C(=O)N3CCCCCC3)c4CCCCCn24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D11 compound treatment 0.122 -0.0951 -1.0 0.095 -0.136 -1.62 -1.8542 -0.9727 3043497 ChemDiv3_016269 Cc1cccc(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D12 compound treatment 0.114 -0.103 -1.08 0.113 -0.118 -1.41 -1.7613 -0.9915 3042416 ChemDiv3_016270 CC1CCCN(CCCNC(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D13 compound treatment 0.184 -0.0331 -0.35 0.201 -0.0297 -0.36 -0.497 -0.9999 3042419 ChemDiv3_016271 CCN1CCC(CC1)N(Cc2ccc(F)cc2)C(=O)Nc3ccccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D14 compound treatment 0.23 0.0129 0.14 0.264 0.0333 0.4 0.3776 0.8976 3042422 ChemDiv3_016272 CSc1ncc(C(=O)NCCc2ccccc2)c(C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D15 compound treatment 0.188 -0.0291 -0.31 0.193 -0.0377 -0.45 -0.5349 -0.9819 3124472 ChemDiv3_016273 COc1ccc(CCNC(=O)Cn2c(SCc3ccc(C)cc3)nc4cccnc24)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D16 compound treatment 0.199 -0.0181 -0.19 0.253 0.0223 0.27 0.0544 0.1661 3042426 ChemDiv3_016274 CCN(c1cccc(C)c1)S(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D17 compound treatment 0.177 -0.0401 -0.42 0.231 2.81E-4 0.0 -0.2951 -0.7014 3124473 ChemDiv3_016275 CNC(=O)CN1C(=O)c2cccnc2Oc3ccc(Cl)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D18 compound treatment 0.221 0.00394 0.04 0.234 0.00328 0.04 0.057 0.9997 3124474 ChemDiv3_016276 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D19 compound treatment 0.243 0.0259 0.27 0.262 0.0313 0.37 0.4573 0.9878 3042431 ChemDiv3_016277 CC(C)CCNS(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D20 compound treatment 0.272 0.0549 0.58 0.349 0.118 1.42 1.4087 0.9217 3124475 ChemDiv3_016278 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(CCN2C(=O)c3cccnc3C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D21 compound treatment 0.698 0.481 5.05 0.777 0.546 6.54 8.1933 0.9919 3042509 ChemDiv3_016279 CCOC(=O)c1cc(C)n(c1C)c2ccc(cc2)C(=O)NC3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D22 compound treatment 0.201 -0.0161 -0.17 0.23 -7.19E-4 -0.01 -0.1254 -0.7422 3124476 ChemDiv3_016280 Cc1ccc(cc1)n2c(=O)n(CC(=O)N)c3c4cc(C)ccc4n(C)c3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D23 mock treatment 0.229 0.0119 0.13 0.243 0.0123 0.15 0.1926 0.9969 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 D24 mock treatment 0.281 0.0639 0.67 0.244 0.0133 0.16 0.5872 0.8509 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E01 compound treatment 0.179 -0.0381 -0.4 0.211 -0.0197 -0.24 -0.4495 -0.9684 3124477 ChemDiv3_016281 CCN1CCCC1CNC(=O)C2C(N(CC(C)C)C(=O)c3ccccc23)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E02 compound treatment 0.165 -0.0521 -0.55 0.153 -0.0777 -0.93 -1.0442 -0.968 3042513 ChemDiv3_016282 CCCNC(=O)CCn1c(=O)c2cccn2c3cccnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E03 compound treatment 0.258 0.0409 0.43 0.301 0.0703 0.84 0.8986 0.9515 3042515 ChemDiv3_016283 COc1cccc(c1)n2cc(C(=O)NC3CCCC3)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E04 compound treatment 0.219 0.00194 0.02 0.264 0.0333 0.4 0.296 0.7423 3124478 ChemDiv3_016284 CSc1ncc(C(=O)O)c(n1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E05 compound treatment 0.185 -0.0321 -0.34 0.237 0.00628 0.08 -0.185 -0.5361 3124479 ChemDiv3_016285 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E06 compound treatment 0.207 -0.0101 -0.11 0.275 0.0443 0.53 0.2999 0.5551 3042523 ChemDiv3_016286 Cc1ccc(NC(=O)CCc2cn(Cc3ccc(Cl)cc3)c4ccccc24)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E07 compound treatment 0.78 0.563 5.91 0.857 0.626 7.49 9.4791 0.9931 3124480 ChemDiv3_016287 COc1cccc(c1)N2CCN(CC2)S(=O)(=O)c3cc4OCCN(C)c4cc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E08 compound treatment 0.295 0.0779 0.82 0.353 0.122 1.46 1.6133 0.9623 3124481 ChemDiv3_016288 Fc1ccc(Cn2cc(CCC(=O)NCC3CCCO3)c4ccccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E09 compound treatment 1.191 0.974 10.23 1.136 0.905 10.83 14.8918 0.9996 3042528 ChemDiv3_016289 COCCN(Cc1ccco1)C(=O)c2noc-3c2COc4ccc(C)cc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E10 compound treatment 0.332 0.115 1.21 0.389 0.158 1.89 2.1927 0.9764 3124482 ChemDiv3_016290 COc1ccc(cc1)c2noc(CC(=O)NCCC(C)C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E11 compound treatment 0.137 -0.0801 -0.84 0.18 -0.0507 -0.61 -1.0237 -0.9872 3042577 ChemDiv3_016291 O=C(CCS(=O)(=O)c1ccc2NC(=O)COc2c1)N3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E12 compound treatment 0.149 -0.0681 -0.71 0.18 -0.0507 -0.61 -0.9346 -0.9967 3124483 ChemDiv3_016292 Cc1nc2ccc(cc2s1)S(=O)(=O)CCC(=O)NCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E13 compound treatment 0.162 -0.0551 -0.58 0.189 -0.0417 -0.5 -0.7619 -0.9973 3124484 ChemDiv3_016293 CCC(C)NC(=O)C1CCCN1S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E14 compound treatment 0.172 -0.0451 -0.47 0.218 -0.0127 -0.15 -0.4423 -0.8896 3042580 ChemDiv3_016294 Cc1nc2sccn2c(=O)c1S(=O)(=O)Nc3ccc4OCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E15 compound treatment 0.142 -0.0751 -0.79 0.186 -0.0447 -0.54 -0.9358 -0.9822 3042582 ChemDiv3_016295 CCCNS(=O)(=O)c1c[nH]c(c1)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E16 compound treatment 0.146 -0.0711 -0.75 0.139 -0.0917 -1.1 -1.3037 -0.9824 3124485 ChemDiv3_016296 Cc1cccc(CN2CCC(CNC(=O)NCc3noc4ccccc34)CC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E17 compound treatment 0.152 -0.0651 -0.68 0.204 -0.0267 -0.32 -0.7092 -0.9401 3042589 ChemDiv3_016297 COC(=O)c1cc(c[nH]1)S(=O)(=O)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E18 compound treatment 0.178 -0.0391 -0.41 0.262 0.0313 0.37 -0.0255 -0.0458 3124594 ChemDiv3_016298 COc1ccc(NC(=O)NCc2noc3ccc(C)cc23)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E19 compound treatment 0.198 -0.0191 -0.2 0.22 -0.0107 -0.13 -0.2322 -0.9768 3124595 ChemDiv3_016299 CCn1c(C(=O)O)c(CNCc2ccccc2)c3ccc(OC)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E20 compound treatment 0.382 0.165 1.73 0.467 0.236 2.83 3.2239 0.9724 3042593 ChemDiv3_016300 Cc1ccc(cc1)S(=O)(=O)c2c(O)c3ccc(cc3[nH]c2=O)C(=O)NCc4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E21 compound treatment 0.207 -0.0101 -0.11 0.244 0.0133 0.16 0.0376 0.1972 3124596 ChemDiv3_016301 CCOC(=O)C1CCN(CC1)C(=O)CCN2C(=O)c3ccccc3Sc4ncccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E22 compound treatment 0.244 0.0269 0.28 0.32 0.0893 1.07 0.9554 0.8646 3042635 ChemDiv3_016302 O=C(CN1C(=O)CSc2cc(ccc12)S(=O)(=O)N3CCCC3)NC4CCCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E23 mock treatment 0.214 -0.00306 -0.03 0.229 -0.00172 -0.02 -0.0373 -0.9766 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 E24 mock treatment 0.258 0.0409 0.43 0.274 0.0433 0.52 0.6702 0.9957 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F01 compound treatment 0.181 -0.0361 -0.38 0.169 -0.0617 -0.74 -0.79 -0.9519 3124597 ChemDiv3_016303 CN1CCN(CC1)c2ccc3nnc(CCC(=O)Nc4nccs4)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F02 compound treatment 0.195 -0.0221 -0.23 0.209 -0.0217 -0.26 -0.3476 -0.9984 3042639 ChemDiv3_016304 COc1cccc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F03 compound treatment 0.172 -0.0451 -0.47 0.142 -0.0887 -1.06 -1.0852 -0.9338 3124598 ChemDiv3_016305 COc1ccc(cc1)c2noc(n2)N3CCCC(C3)C(=O)NCCCN4CCC(C)CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F04 compound treatment 0.157 -0.0601 -0.63 0.156 -0.0747 -0.89 -1.0782 -0.9854 3124599 ChemDiv3_016306 CN(C1CCCCC1)c2ncnc3n4CCCCCc4nc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F05 compound treatment 0.124 -0.0931 -0.98 0.128 -0.103 -1.23 -1.5601 -0.9936 3042646 ChemDiv3_016307 CCNC(=O)C1CCN(CC1)c2nn3cc(nc3s2)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F06 compound treatment 0.122 -0.0951 -1.0 0.111 -0.12 -1.43 -1.7188 -0.9844 1594579 ChemDiv3_016308 COc1ccc(CC(=O)Nc2ccc(cc2)c3nnc4CCCCCn34)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F07 compound treatment 0.713 0.496 5.21 0.742 0.511 6.12 8.0086 0.9968 3124600 ChemDiv3_016309 CCC1CN(C(=O)NCc2ccc(C)cc2)c3ccccc3S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F08 compound treatment 0.171 -0.0461 -0.48 0.182 -0.0487 -0.58 -0.7543 -0.9957 3042650 ChemDiv3_016310 Cc1cc(C)n(n1)c2nc3cc(Cl)ccc3nc2NCc4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F09 compound treatment 0.113 -0.104 -1.09 0.106 -0.125 -1.49 -1.828 -0.9883 3124601 ChemDiv3_016311 CC1CCN(CC2CCN(CC2)C(=O)Nc3ccc(Br)c(C)c3)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F10 compound treatment 0.369 0.152 1.6 0.471 0.24 2.87 3.1612 0.9614 3124602 ChemDiv3_016312 CCN(Cc1ccccc1)C(=O)c2nc(c3ccc(Cl)cc3)n4CCCCCc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F11 compound treatment 0.127 -0.0901 -0.95 0.104 -0.127 -1.52 -1.7409 -0.9742 3124603 ChemDiv3_016313 CCOC(=O)Cc1ccc(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F12 compound treatment 0.154 -0.0631 -0.66 0.201 -0.0297 -0.36 -0.7198 -0.9575 3042656 ChemDiv3_016314 CCOc1ccccc1N(CC)C(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F13 compound treatment 0.149 -0.0681 -0.71 0.17 -0.0607 -0.73 -1.0192 -1.0 3124604 ChemDiv3_016315 O=C(CSc1nc2cccnc2[nH]1)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F14 compound treatment 0.159 -0.0581 -0.61 0.22 -0.0107 -0.13 -0.5219 -0.8375 3124605 ChemDiv3_016316 CSc1ncc(C(=O)NC2CCCCC2)c(C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F15 compound treatment 0.197 -0.0201 -0.21 0.232 0.00128 0.02 -0.1382 -0.6539 3043779 ChemDiv3_016317 Cc1ccc(CNC(=O)Cn2c(SCc3ccccc3F)nc4cccnc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F16 compound treatment 0.153 -0.0641 -0.67 0.217 -0.0137 -0.16 -0.5918 -0.8545 3043780 ChemDiv3_016318 CN(C1CCCCC1)S(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F17 compound treatment 0.552 0.335 3.52 0.701 0.47 5.63 6.4661 0.9744 3043781 ChemDiv3_016319 Clc1ccc2Oc3ncccc3C(=O)N(CC(=O)N4CCc5ccccc45)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F18 compound treatment 0.338 0.121 1.27 0.438 0.207 2.48 2.6518 0.9517 3043782 ChemDiv3_016320 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F19 compound treatment 0.42 0.203 2.13 0.515 0.284 3.4 3.9122 0.9747 3043783 ChemDiv3_016321 CCc1cccc(NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F20 compound treatment 0.53 0.313 3.29 0.613 0.382 4.57 5.5582 0.9869 3043784 ChemDiv3_016322 CN(Cc1ccccc1)S(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F21 compound treatment 0.179 -0.0381 -0.4 0.21 -0.0207 -0.25 -0.458 -0.9736 3124606 ChemDiv3_016323 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F22 compound treatment 1.265 1.05 11.01 1.215 0.984 11.78 16.1097 0.9994 3043785 ChemDiv3_016324 CCn1c(=O)n(c2ccccc2)c(=O)c3n(C)c4ccc(C)cc4c13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F23 mock treatment 0.232 0.0149 0.16 0.261 0.0303 0.36 0.3671 0.9299 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 F24 mock treatment 0.197 -0.0201 -0.21 0.251 0.0203 0.24 0.0226 0.0703 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G01 compound treatment 0.205 -0.0121 -0.13 0.185 -0.0457 -0.55 -0.4764 -0.8484 3124607 ChemDiv3_016325 CC1CCCCN1CCNC(=O)C2C(N(C3CCCC3)C(=O)c4ccccc24)c5cccs5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G02 compound treatment 0.16 -0.0571 -0.6 0.161 -0.0697 -0.83 -1.0136 -0.9868 3043786 ChemDiv3_016326 CC1CCC(CC1)NC(=O)CCn2c(=O)c3cccn3c4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G03 compound treatment 0.23 0.0129 0.14 0.281 0.0503 0.6 0.5215 0.8455 3124608 ChemDiv3_016327 COc1cccc(c1)n2cc(C(=O)Nc3cccnc3)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G04 compound treatment 0.926 0.709 7.45 0.956 0.725 8.68 11.4009 0.9971 3043787 ChemDiv3_016328 Cn1cc(CCC(=O)N2CCc3ccccc23)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G05 compound treatment 0.32 0.103 1.08 0.366 0.135 1.62 1.909 0.9808 3124609 ChemDiv3_016329 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)N(CC=C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G06 compound treatment 0.22 0.00294 0.03 0.294 0.0633 0.76 0.5572 0.7353 3124610 ChemDiv3_016330 Clc1ccccc1Cn2cc(CCC(=O)N3CCc4ccccc34)c5ccccc25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G07 compound treatment 0.178 -0.0391 -0.41 0.202 -0.0287 -0.34 -0.5331 -0.9961 3043788 ChemDiv3_016331 CCCNS(=O)(=O)c1cc2OCCN(C)c2cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G08 compound treatment 0.319 0.102 1.07 0.377 0.146 1.75 1.9946 0.9722 3124611 ChemDiv3_016332 Fc1ccc(Cn2cc(CCC(=O)NC3CCCc4ccccc34)c5ccccc25)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G09 compound treatment 0.108 -0.109 -1.15 0.088 -0.143 -1.71 -2.0174 -0.9811 3043789 ChemDiv3_016333 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NCCCN4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G10 compound treatment 0.424 0.207 2.17 0.668 0.437 5.23 5.2363 0.9243 3124612 ChemDiv3_016334 COc1ccc(cc1)c2noc(CC(=O)N(C)c3ccccc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G11 compound treatment 0.157 -0.0601 -0.63 0.192 -0.0387 -0.46 -0.7736 -0.9885 3124613 ChemDiv3_016335 O=C(CCS(=O)(=O)c1ccc2NC(=O)COc2c1)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G12 compound treatment 0.2 -0.0171 -0.18 0.312 0.0813 0.97 0.5609 0.5673 3043790 ChemDiv3_016336 COc1ccc(cc1)N2CCN(CC2)C(=O)CCS(=O)(=O)c3ccc4nc(C)sc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G13 compound treatment 0.222 0.00494 0.05 0.231 2.81E-4 0.0 0.039 0.7514 3124614 ChemDiv3_016337 CCCN(CCC)S(=O)(=O)c1c[nH]c(c1)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G14 compound treatment 0.183 -0.0341 -0.36 0.209 -0.0217 -0.26 -0.4367 -0.9877 3043791 ChemDiv3_016338 O=S(=O)(c1nnn2c3ccsc3c(nc12)N4CCCCC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G15 compound treatment 0.157 -0.0601 -0.63 0.177 -0.0537 -0.64 -0.9005 -1.0 3124615 ChemDiv3_016339 COC(=O)c1cc(c[nH]1)S(=O)(=O)NCC2CCCO2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G16 compound treatment 0.15 -0.0671 -0.7 0.21 -0.0207 -0.25 -0.6733 -0.9018 3124616 ChemDiv3_016340 Cc1ccc(NC(=O)NCc2noc3ccccc23)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G17 compound treatment 0.155 -0.0621 -0.65 0.227 -0.00372 -0.04 -0.4924 -0.7536 3043792 ChemDiv3_016341 COC(=O)c1cc(c[nH]1)S(=O)(=O)N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G18 compound treatment 0.238 0.0209 0.22 0.321 0.0903 1.08 0.9193 0.834 3124617 ChemDiv3_016342 CN(C1CCCCC1)C(=O)NCc2noc3ccc(C)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G19 compound treatment 0.219 0.00194 0.02 0.319 0.0883 1.06 0.7613 0.7206 3043793 ChemDiv3_016343 COc1ccc2c(CNCCc3ccccc3OC)c(C(=O)O)n(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G20 compound treatment 0.25 0.0329 0.35 0.32 0.0893 1.07 0.9999 0.8906 3124618 ChemDiv3_016344 CC1CN(C(=O)C)c2ccc(cc2O1)S(=O)(=O)N(C)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G21 compound treatment 0.235 0.0179 0.19 0.327 0.0963 1.15 0.9478 0.812 3124619 ChemDiv3_016345 Cc1ccc(Cl)cc1NC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G22 compound treatment 0.262 0.0449 0.47 0.308 0.0773 0.92 0.9875 0.9513 3043794 ChemDiv3_016346 CC(C)N(Cc1ccccc1)C(=O)CN2C(=O)CSc3cc(ccc23)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G23 mock treatment 0.187 -0.0301 -0.32 0.224 -0.00672 -0.08 -0.2801 -0.8597 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 G24 mock treatment 0.218 9.38E-4 0.01 0.284 0.0533 0.64 0.4577 0.7179 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H01 compound treatment 0.191 -0.0261 -0.27 0.17 -0.0607 -0.73 -0.7072 -0.911 3124620 ChemDiv3_016347 CCOc1ccccc1NC(=O)CCc2nnc3ccc(nn23)N4CCN(C)CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H02 compound treatment 0.154 -0.0631 -0.66 0.15 -0.0807 -0.97 -1.1512 -0.9831 3043795 ChemDiv3_016348 CCCCN(C)C(=O)Nc1cn(C)c(=O)c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H03 compound treatment 0.591 0.374 3.93 0.616 0.385 4.61 6.0366 0.9968 3124728 ChemDiv3_016349 CCN(C(=O)C1CCCN(C1)c2nc(no2)c3ccc(OC)cc3)c4ccccc4F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H04 compound treatment 0.093 -0.124 -1.3 0.071 -0.16 -1.91 -2.2726 -0.9826 3043796 ChemDiv3_016350 CCN(c1ccc(CC)cc1)c2ncnc3n4CCCCCc4nc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H05 compound treatment 0.173 -0.0441 -0.46 0.216 -0.0147 -0.18 -0.4518 -0.9124 3124729 ChemDiv3_016351 COc1ccccc1NC(=O)C2CCN(CC2)c3nn4cc(nc4s3)c5ccc(C)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H06 compound treatment 0.151 -0.0661 -0.69 0.13 -0.101 -1.21 -1.3427 -0.9656 3124730 ChemDiv3_016352 CCOc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H07 compound treatment 0.257 0.0399 0.42 0.382 0.151 1.81 1.5765 0.8485 3043797 ChemDiv3_016353 CNC(=O)Cn1c(cc2ccccc12)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H08 compound treatment 0.162 -0.0551 -0.58 0.219 -0.0117 -0.14 -0.5081 -0.8538 3124731 ChemDiv3_016354 Cc1cc(C)n(n1)c2nc3cc(Cl)ccc3nc2NCCN4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H09 compound treatment 0.121 -0.0961 -1.01 0.104 -0.127 -1.52 -1.7855 -0.9804 3043798 ChemDiv3_016355 COC(=O)c1ccccc1NC(=O)N2CCC(CN3CCOCC3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H10 compound treatment 0.418 0.201 2.11 0.564 0.333 3.99 4.3119 0.9557 3124732 ChemDiv3_016356 Clc1ccc(cc1)c2nc(C(=O)N3CCc4ccccc34)c5CCCCCn25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H11 compound treatment 0.103 -0.114 -1.2 0.092 -0.139 -1.66 -2.0207 -0.9872 3124733 ChemDiv3_016357 O=C(Nc1ccc2OCCOc2c1)N3CCC(CN4CCc5ccccc5C4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H12 compound treatment 0.263 0.0459 0.48 0.341 0.11 1.32 1.2742 0.9069 3043799 ChemDiv3_016358 COc1ccc(cc1OC)c2noc(CSCC(=O)Nc3ccc(cc3)C(C)C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H13 compound treatment 0.167 -0.0501 -0.53 0.196 -0.0347 -0.42 -0.6655 -0.9932 3124734 ChemDiv3_016359 CN(C(=O)CSc1nc2cccnc2[nH]1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H14 compound treatment 0.193 -0.0241 -0.25 0.261 0.0303 0.36 0.0775 0.1754 3043800 ChemDiv3_016360 CSc1ncc(C(=O)N2CCCc3ccccc23)c(C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H15 compound treatment 0.306 0.0889 0.93 0.356 0.125 1.5 1.7204 0.9741 3124735 ChemDiv3_016361 CC1CCc2c(C1)cc(C)n2c3ccc(cc3)C(=O)NCC4CCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H16 compound treatment 0.164 -0.0531 -0.56 0.233 0.00228 0.03 -0.3748 -0.6717 3043801 ChemDiv3_016362 CSc1cccc(NS(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H17 compound treatment 0.276 0.0589 0.62 0.311 0.0803 0.96 1.1169 0.9774 3124736 ChemDiv3_016363 CCc1cccc(NS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H18 compound treatment 0.179 -0.0381 -0.4 0.237 0.00628 0.08 -0.2295 -0.5643 3124737 ChemDiv3_016364 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H19 compound treatment 0.387 0.17 1.78 0.433 0.202 2.42 2.9734 0.9888 3043802 ChemDiv3_016365 CC1CCCC(NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H20 compound treatment 0.179 -0.0381 -0.4 0.263 0.0323 0.39 -0.0096 -0.0172 3124738 ChemDiv3_016366 O=C1N(Cc2ccc(cc2)S(=O)(=O)NC3CCCC3)C(=O)c4ncccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H21 compound treatment 0.31 0.0929 0.98 0.401 0.17 2.04 2.1308 0.9432 3124739 ChemDiv3_016367 CN(Cc1ccccc1)C(=O)CN(C)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H22 compound treatment 0.157 -0.0601 -0.63 0.2 -0.0307 -0.37 -0.7059 -0.9669 3043803 ChemDiv3_016368 CCc1ccccc1NCc2c(O)c(C)ncc2CO 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H23 mock treatment 0.191 -0.0261 -0.27 0.233 0.00228 0.03 -0.1743 -0.6335 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 H24 mock treatment 0.21 -0.00706 -0.07 0.226 -0.00472 -0.06 -0.0924 -0.9909 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I01 compound treatment 0.641 0.424 4.45 0.656 0.425 5.09 6.7463 0.9978 3124740 ChemDiv3_016369 COc1ccc(cc1)n2cc(C(=O)N(Cc3ccco3)C4CCCC4)c5ccccc5c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I02 compound treatment 0.137 -0.0801 -0.84 0.13 -0.101 -1.21 -1.4467 -0.9845 3043804 ChemDiv3_016370 CCN1CCCC1CNC(=O)CCn2c(=O)c3cccn3c4cccnc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I03 compound treatment 0.55 0.333 3.5 0.684 0.453 5.42 6.3074 0.9775 3124741 ChemDiv3_016371 COc1cccc(c1)n2cc(C(=O)NCc3ccccc3Cl)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I04 compound treatment 0.291 0.0739 0.78 0.397 0.166 1.99 1.9559 0.9158 3043805 ChemDiv3_016372 Cn1cc(CCC(=O)NCc2ccccc2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I05 compound treatment 0.217 -6.25E-5 0.0 0.216 -0.0147 -0.18 -0.125 -0.7097 3124742 ChemDiv3_016373 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)N3CCc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I06 compound treatment 1.063 0.846 8.88 1.245 1.01 12.14 14.8633 0.9883 3043806 ChemDiv3_016374 CNC(=O)CCc1cn(Cc2ccccc2Cl)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I07 compound treatment 0.129 -0.0881 -0.92 0.133 -0.0977 -1.17 -1.4807 -0.9933 3124743 ChemDiv3_016375 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NC4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I08 compound treatment 0.233 0.0159 0.17 0.305 0.0743 0.89 0.7468 0.8258 3124744 ChemDiv3_016376 CC(CCc1ccccc1)NC(=O)CCc2cn(Cc3ccc(F)cc3)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I09 compound treatment 0.192 -0.0251 -0.26 0.169 -0.0617 -0.74 -0.7083 -0.9035 3043807 ChemDiv3_016377 Cc1ccc(cc1)c2nc(C(=O)N3CCN(Cc4ccccc4)CC3)c5CCCCCn25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I10 compound treatment 0.359 0.142 1.49 0.542 0.311 3.72 3.6876 0.9192 3124745 ChemDiv3_016378 COc1ccc(cc1)c2noc(CC(=O)N(C(C)C)C3CCCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I11 compound treatment 0.19 -0.0271 -0.28 0.197 -0.0337 -0.4 -0.4862 -0.9853 3124746 ChemDiv3_016379 COc1ccccc1N(C)C(=O)CCS(=O)(=O)c2ccc3NC(=O)COc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I12 compound treatment 0.233 0.0159 0.17 0.326 0.0953 1.14 0.9245 0.8023 3043808 ChemDiv3_016380 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc4N(C)C(=O)C(C)(C)c4c3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I13 compound treatment 0.167 -0.0501 -0.53 0.195 -0.0357 -0.43 -0.674 -0.9947 3124747 ChemDiv3_016381 CCc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I14 compound treatment 0.175 -0.0421 -0.44 0.186 -0.0447 -0.54 -0.6907 -0.9955 3043809 ChemDiv3_016382 O=S(=O)(c1nnn2c3ccsc3c(Nc4ccccc4)nc12)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I15 compound treatment 0.173 -0.0441 -0.46 0.221 -0.00972 -0.12 -0.4095 -0.8581 3124748 ChemDiv3_016383 COC(=O)c1cc(c[nH]1)S(=O)(=O)NC2CCCCC2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I16 compound treatment 0.379 0.162 1.7 0.526 0.295 3.53 3.7008 0.9438 3124749 ChemDiv3_016384 O=C(NCc1noc2ccccc12)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I17 compound treatment 0.221 0.00394 0.04 0.303 0.0723 0.86 0.6408 0.7401 3043810 ChemDiv3_016385 O=C(CCNS(=O)(=O)c1ccc2[nH]c(nc2c1)c3ccccc3)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I18 compound treatment 0.283 0.0659 0.69 0.345 0.114 1.37 1.4565 0.9503 3124750 ChemDiv3_016386 CC1CCCC(NC(=O)NCc2noc3ccc(C)cc23)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I19 compound treatment 0.143 -0.0741 -0.78 0.159 -0.0717 -0.86 -1.1568 -0.9988 3124751 ChemDiv3_016387 COc1ccc2c(CNCCc3ccccc3Cl)c([nH]c2c1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I20 compound treatment 0.309 0.0919 0.97 0.331 0.1 1.2 1.5312 0.9942 3043811 ChemDiv3_016388 CSc1cccc(NS(=O)(=O)c2ccc3N(CC(C)Oc3c2)C(=O)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I21 compound treatment 0.191 -0.0261 -0.27 0.254 0.0233 0.28 0.0034 0.0087 3124752 ChemDiv3_016389 Clc1ccc(CCNC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I22 compound treatment 0.232 0.0149 0.16 0.309 0.0783 0.94 0.7732 0.8142 3043812 ChemDiv3_016390 O=C(CN1C(=O)CSc2cc(ccc12)S(=O)(=O)N3CCCC3)NCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I23 mock treatment 0.17 -0.0471 -0.49 0.192 -0.0387 -0.46 -0.6771 -0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 I24 mock treatment 0.209 -0.00806 -0.08 0.238 0.00728 0.09 0.0017 0.0142 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J01 compound treatment 0.292 0.0749 0.79 0.245 0.0143 0.17 0.6773 0.841 3124753 ChemDiv3_016391 CCn1c(=O)c2sccc2n3c(CCCC(=O)Nc4ccccc4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J02 compound treatment 0.174 -0.0431 -0.45 0.206 -0.0247 -0.3 -0.5289 -0.9788 3043962 ChemDiv3_016392 CCN(C(=O)Nc1cn(C)c(=O)c2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J03 compound treatment 0.184 -0.0331 -0.35 0.186 -0.0447 -0.54 -0.6239 -0.9781 3043963 ChemDiv3_016393 COc1ccc(cc1)c2noc(n2)N3CCCC(C3)C(=O)Nc4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J04 compound treatment 0.139 -0.0781 -0.82 0.183 -0.0477 -0.57 -0.9834 -0.9844 3043965 ChemDiv3_016394 COc1ccc(Nc2cc(C)c3cc(NC(=O)c4ccc(OC)cc4)ccc3n2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J05 compound treatment 0.129 -0.0881 -0.92 0.11 -0.121 -1.44 -1.6753 -0.9768 3044021 ChemDiv3_016395 Cc1ccc(cc1)c2cn3nc(sc3n2)N4CCC(CC4)C(=O)NCCCN5CCCCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J06 compound treatment 0.162 -0.0551 -0.58 0.186 -0.0447 -0.54 -0.7872 -0.9992 3044022 ChemDiv3_016396 CC(CC(=O)N(C)Cc1ccccc1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J07 compound treatment 0.18 -0.0371 -0.39 0.262 0.0313 0.37 -0.0106 -0.0196 3044024 ChemDiv3_016397 CC1Cn2cc(C(=O)NCc3ccccc3)c(=O)c4c(Cl)ccc(O1)c24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J08 compound treatment 0.343 0.126 1.32 0.451 0.22 2.64 2.7989 0.9492 3044025 ChemDiv3_016398 COc1ccc(cc1OC)C2C3=C(CCCC3=O)Nc4[nH]nc(c24)c5ccc(Cl)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J09 compound treatment 0.147 -0.0701 -0.74 0.154 -0.0767 -0.92 -1.1694 -0.994 3044027 ChemDiv3_016399 Cc1ccc(Cl)cc1NC(=O)N2CCC(CN3CCOCC3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J10 compound treatment 0.164 -0.0531 -0.56 0.198 -0.0327 -0.39 -0.6709 -0.9851 3044028 ChemDiv3_016400 COc1ccc(cc1OC)c2noc(NCCCN3CCCC3=O)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J11 compound treatment 0.111 -0.106 -1.11 0.103 -0.128 -1.53 -1.8682 -0.9879 3124754 ChemDiv3_016401 CCOc1ccc(NC(=O)N2CCCC(CN3CCc4ccccc4C3)C2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J12 compound treatment 0.323 0.106 1.11 0.419 0.188 2.25 2.3796 0.9471 3044030 ChemDiv3_016402 CCCCN(C)C(=O)Cn1ncc2c3ccccc3n(CCC)c2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J13 compound treatment 0.168 -0.0491 -0.52 0.178 -0.0527 -0.63 -0.8104 -0.995 3124866 ChemDiv3_016403 CCC(Sc1nc2cccnc2[nH]1)C(=O)NCc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J14 compound treatment 0.155 -0.0621 -0.65 0.213 -0.0177 -0.21 -0.6108 -0.8911 3124867 ChemDiv3_016404 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J15 compound treatment 0.277 0.0599 0.63 0.375 0.144 1.73 1.6658 0.9066 3044032 ChemDiv3_016405 CC1CCc2c(C1)cc(C)n2c3ccc(cc3)C(=O)N4CCC5(CC4)OCCO5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J16 compound treatment 0.177 -0.0401 -0.42 0.194 -0.0367 -0.44 -0.6082 -0.9998 3124868 ChemDiv3_016406 CCC(C)(C)NS(=O)(=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J17 compound treatment 0.195 -0.0221 -0.23 0.24 0.00928 0.11 -0.0853 -0.3321 3044034 ChemDiv3_016407 CCC(C)NS(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J18 compound treatment 0.216 -0.00106 -0.01 0.244 0.0133 0.16 0.1045 0.6558 3124869 ChemDiv3_016408 Cc1cccc(NS(=O)(=O)c2ccc(CCN3C(=O)c4cccnc4C3=O)cc2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J19 compound treatment 0.334 0.117 1.23 0.467 0.236 2.83 2.8674 0.9303 3124870 ChemDiv3_016409 CN(c1cccc(C)c1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J20 compound treatment 0.422 0.205 2.15 0.518 0.287 3.44 3.9524 0.9746 3044036 ChemDiv3_016410 CCc1ccc(NS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J21 compound treatment 0.21 -0.00706 -0.07 0.264 0.0333 0.4 0.2291 0.5657 3124871 ChemDiv3_016411 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3ccc4[nH]c5CCCCc5c4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J22 compound treatment 0.186 -0.0311 -0.33 0.215 -0.0157 -0.19 -0.3637 -0.9658 3044037 ChemDiv3_016412 Fc1ccc(F)c(NS(=O)(=O)c2ccc(cc2)n3cccn3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J23 mock treatment 0.21 -0.00706 -0.07 0.227 -0.00372 -0.04 -0.0839 -0.9701 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 J24 mock treatment 0.202 -0.0151 -0.16 0.227 -0.00372 -0.04 -0.1433 -0.8721 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K01 compound treatment 0.222 0.00494 0.05 0.209 -0.0217 -0.26 -0.1471 -0.5551 3124872 ChemDiv3_016413 COc1cccc(c1)n2cc(C(=O)N3CCCCCC3)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K02 compound treatment 0.217 -6.25E-5 0.0 0.225 -0.00572 -0.07 -0.0488 -0.7139 3124873 ChemDiv3_016414 Cc1cccc(N2CCN(CCNC(=O)CCn3c(=O)c4cccn4c5cccnc35)CC2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K03 compound treatment 0.172 -0.0451 -0.47 0.199 -0.0317 -0.38 -0.603 -0.994 3044040 ChemDiv3_016415 COc1cccc(c1)n2cc(C(=O)N3C(C)CCCC3C)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K04 compound treatment 0.694 0.477 5.01 0.708 0.477 5.71 7.5798 0.9979 3124874 ChemDiv3_016416 Cn1cc(CCC(=O)NCCCc2ccccc2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K05 compound treatment 0.275 0.0579 0.61 0.326 0.0953 1.14 1.2364 0.9568 3044043 ChemDiv3_016417 CCN(c1cccc(C)c1)S(=O)(=O)c2ccc3NC(=O)C(C)Sc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K06 compound treatment 0.219 0.00194 0.02 0.305 0.0743 0.89 0.6428 0.7231 3124875 ChemDiv3_016418 Cc1ccc(Cn2cc(CCC(=O)N3CCc4ccccc34)c5ccccc25)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K07 compound treatment 0.354 0.137 1.44 0.371 0.14 1.68 2.2038 0.997 3044045 ChemDiv3_016419 CC1CCN(CC1)C(=O)c2noc-3c2COc4ccc(C)cc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K08 compound treatment 0.227 0.00994 0.1 0.316 0.0853 1.02 0.7953 0.7754 3044084 ChemDiv3_016420 COc1ccc(cc1)c2noc(CC(=O)Nc3cccc(OC)c3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K09 compound treatment 0.2 -0.0171 -0.18 0.174 -0.0567 -0.68 -0.6066 -0.8642 3044085 ChemDiv3_016421 CCCCN(C)C(=O)c1nc(c2ccc(C)cc2)n3CCCCCc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K10 compound treatment 0.311 0.0939 0.99 0.335 0.104 1.25 1.5799 0.9932 3044087 ChemDiv3_016422 COc1ccc(cc1)c2noc(CC(=O)NCCCN3C(C)CCCC3C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K11 compound treatment 0.195 -0.0221 -0.23 0.21 -0.0207 -0.25 -0.3391 -0.9994 3044089 ChemDiv3_016423 CC1CCN(CC1)C(=O)CCS(=O)(=O)c2ccc3NC(=O)CSc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K12 compound treatment 0.202 -0.0151 -0.16 0.241 0.0103 0.12 -0.0249 -0.1242 3044091 ChemDiv3_016424 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)N3CCCC3C(=O)NCc4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K13 compound treatment 0.171 -0.0461 -0.48 0.236 0.00528 0.06 -0.2974 -0.6096 3044092 ChemDiv3_016425 CCc1ccc(NC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K14 compound treatment 0.171 -0.0461 -0.48 0.248 0.0173 0.21 -0.1959 -0.3723 3124876 ChemDiv3_016426 O=C(NCc1noc2ccccc12)Nc3ccc4OCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K15 compound treatment 0.245 0.0279 0.29 0.273 0.0423 0.51 0.5652 0.9664 3124877 ChemDiv3_016427 CC1CCCC(NC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCCC3)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K16 compound treatment 0.133 -0.0841 -0.88 0.138 -0.0927 -1.11 -1.4087 -0.9936 3044095 ChemDiv3_016428 O=C(NCc1noc2ccccc12)Nc3nccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K17 compound treatment 0.145 -0.0721 -0.76 0.151 -0.0797 -0.95 -1.2096 -0.9934 3124878 ChemDiv3_016429 O=C(C1CCCN1S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4)N5CCOCC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K18 compound treatment 0.147 -0.0701 -0.74 0.173 -0.0577 -0.69 -1.0086 -0.9995 3044096 ChemDiv3_016430 CCOC(=O)c1ccccc1NC(=O)NCc2noc3ccc(C)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K19 compound treatment 0.159 -0.0581 -0.61 0.194 -0.0367 -0.44 -0.7418 -0.9871 3124879 ChemDiv3_016431 Cc1ccc2c(CNC3CCCC3)c(C(=O)O)n(C)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K20 compound treatment 0.327 0.11 1.15 0.375 0.144 1.73 2.0371 0.9809 3124880 ChemDiv3_016432 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)NCC3CCC(CC3)C(=O)Nc4cccc(C)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K21 compound treatment 0.167 -0.0501 -0.53 0.2 -0.0307 -0.37 -0.6317 -0.9847 3044099 ChemDiv3_016433 O=C(CCN1C(=O)c2ccccc2Sc3ncccc13)NC4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K22 compound treatment 0.201 -0.0161 -0.17 0.227 -0.00372 -0.04 -0.1507 -0.8641 3124881 ChemDiv3_016434 CCC1Sc2cc(ccc2NC1=O)S(=O)(=O)Nc3cccc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K23 mock treatment 0.177 -0.0401 -0.42 0.196 -0.0347 -0.42 -0.5912 -1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 K24 mock treatment 0.215 -0.00206 -0.02 0.212 -0.0187 -0.22 -0.1737 -0.7719 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L01 compound treatment 0.202 -0.0151 -0.16 0.206 -0.0247 -0.3 -0.321 -0.957 3044102 ChemDiv3_016435 CCn1c(=O)c2sccc2n3c(CCCC(=O)NCc4cccnc4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L02 compound treatment 0.17 -0.0471 -0.49 0.16 -0.0707 -0.85 -0.9478 -0.9672 3124882 ChemDiv3_016436 CCN(Cc1ccccc1)C(=O)Nc2cn(C)c(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L03 compound treatment 0.265 0.0479 0.5 0.272 0.0413 0.49 0.7053 1.0 3044104 ChemDiv3_016437 Fc1cccc(c1)c2nc(C(=O)Nc3ccc(F)cc3F)c4CCCCCn24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L04 compound treatment 0.141 -0.0761 -0.8 0.156 -0.0747 -0.89 -1.197 -0.9984 3124883 ChemDiv3_016438 Cc1cc(Nc2cccc(Cl)c2)nc3ccc(NC(=O)c4ccc(=O)[nH]c4)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L05 compound treatment 0.125 -0.0921 -0.97 0.145 -0.0857 -1.03 -1.4089 -0.9996 3124884 ChemDiv3_016439 CCCCN(C)C(=O)C1CCN(CC1)c2nn3cc(nc3s2)c4ccc(OC)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L06 compound treatment 0.175 -0.0421 -0.44 0.239 0.00828 0.1 -0.2423 -0.5352 3044106 ChemDiv3_016440 CC(CC(=O)Nc1ccc(C)cc1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L07 compound treatment 0.169 -0.0481 -0.5 0.226 -0.00472 -0.06 -0.3969 -0.7813 3124885 ChemDiv3_016441 CC(C)NC(=O)c1cn2CC(C)Oc3ccc(Cl)c(c1=O)c32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L08 compound treatment 0.189 -0.0281 -0.29 0.225 -0.00572 -0.07 -0.2568 -0.8487 3124886 ChemDiv3_016442 Clc1ccc(cc1)c2nc(C(=O)NCc3cccnc3)c4CCCCCn24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L09 compound treatment 0.107 -0.11 -1.16 0.094 -0.137 -1.64 -1.974 -0.9855 3044108 ChemDiv3_016443 CCOc1ccc(NC(=O)N2CCC(CN3CCOCC3)CC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L10 compound treatment 0.843 0.626 6.57 0.998 0.767 9.18 11.1398 0.9866 3044144 ChemDiv3_016444 CCOc1ccc(CCNc2nc(no2)c3ccc(OC)c(OC)c3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L11 compound treatment 0.087 -0.13 -1.37 0.097 -0.134 -1.6 -2.0972 -0.9969 3044145 ChemDiv3_016445 Brc1cccc(NC(=O)N2CCCC(CN3CCc4ccccc4C3)C2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L12 compound treatment 0.159 -0.0581 -0.61 0.21 -0.0207 -0.25 -0.6065 -0.9213 3044147 ChemDiv3_016446 O=C(Cn1ncc2c3ccccc3[nH]c2c1=O)NCCC4=CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L13 compound treatment 0.183 -0.0341 -0.36 0.243 0.0123 0.15 -0.1491 -0.3854 3044148 ChemDiv3_016447 CCC(Sc1nc2cccnc2[nH]1)C(=O)NC3CCC(C)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L14 compound treatment 0.171 -0.0461 -0.48 0.212 -0.0187 -0.22 -0.5004 -0.9387 3044149 ChemDiv3_016448 CCCN(CCC)S(=O)(=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L15 compound treatment 0.281 0.0639 0.67 0.375 0.144 1.73 1.6955 0.9154 3044151 ChemDiv3_016449 Cc1cc2CCCCCc2n1c3ccc(cc3)C(=O)N4CCN(CC4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L16 compound treatment 0.163 -0.0541 -0.57 0.193 -0.0377 -0.45 -0.7206 -0.9935 3124887 ChemDiv3_016450 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L17 compound treatment 0.333 0.116 1.22 0.42 0.189 2.26 2.4624 0.9577 3124888 ChemDiv3_016451 COc1ccc(CCNS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L18 compound treatment 0.383 0.166 1.74 0.458 0.227 2.72 3.1552 0.9769 3044153 ChemDiv3_016452 CCN(c1ccccc1)S(=O)(=O)c2ccc(CCN3C(=O)c4cccnc4C3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L19 compound treatment 0.112 -0.105 -1.1 0.105 -0.126 -1.5 -1.8438 -0.9884 3124889 ChemDiv3_016453 CCN(CC)S(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L20 compound treatment 0.207 -0.0101 -0.11 0.205 -0.0257 -0.31 -0.2923 -0.8984 3044155 ChemDiv3_016454 O=C1N(Cc2ccc(cc2)S(=O)(=O)N3CCc4ccccc34)C(=O)c5ncccc15 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L21 compound treatment 0.209 -0.00806 -0.08 0.286 0.0553 0.66 0.4078 0.6116 3124890 ChemDiv3_016455 CN(CC(=O)N1CCCC1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L22 compound treatment 0.413 0.196 2.06 0.502 0.271 3.25 3.7502 0.9758 3044156 ChemDiv3_016456 CCc1ccccc1NS(=O)(=O)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L23 mock treatment 0.181 -0.0361 -0.38 0.184 -0.0467 -0.56 -0.6631 -0.982 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 L24 mock treatment 0.243 0.0259 0.27 0.271 0.0403 0.48 0.5334 0.9635 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M01 compound treatment 0.229 0.0119 0.13 0.232 0.00128 0.02 0.0995 0.7877 3124891 ChemDiv3_016457 COc1cccc(c1)n2cc(C(=O)NC(C)C)c3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M02 compound treatment 0.18 -0.0371 -0.39 0.221 -0.00972 -0.12 -0.3575 -0.8799 3124892 ChemDiv3_016458 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)N3CCN(CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M03 compound treatment 0.595 0.378 3.97 0.704 0.473 5.66 6.8108 0.9849 3044159 ChemDiv3_016459 COc1cccc(c1)n2cc(C(=O)N3CCC(=CC3)c4ccccc4)c5ccccc5c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M04 compound treatment 0.284 0.0669 0.7 0.338 0.107 1.28 1.4047 0.9599 3125001 ChemDiv3_016460 CCn1cc(CCC(=O)NCc2ccco2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M05 compound treatment 0.117 -0.1 -1.05 0.118 -0.113 -1.35 -1.6967 -0.9924 3125002 ChemDiv3_016461 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)N3CCC(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M06 compound treatment 0.278 0.0609 0.64 0.321 0.0903 1.08 1.2163 0.9688 3044161 ChemDiv3_016462 CC(C)NC(=O)CCc1cn(Cc2ccc(C)cc2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M07 compound treatment 0.114 -0.103 -1.08 0.087 -0.144 -1.72 -1.9813 -0.9751 3125003 ChemDiv3_016463 CCN1CCCC1CNC(=O)c2noc-3c2COc4ccc(C)cc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M08 compound treatment 0.747 0.53 5.57 0.704 0.473 5.66 7.9396 1.0 3044162 ChemDiv3_016464 COc1ccc(cc1)c2noc(CC(=O)N(C)Cc3ccccc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M09 compound treatment 0.138 -0.0791 -0.83 0.145 -0.0857 -1.03 -1.3124 -0.9945 3125004 ChemDiv3_016465 Cc1ccc(cc1)c2nc(C(=O)NCCN3CCc4ccccc4C3)c5CCCCCn25 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M10 compound treatment 0.281 0.0639 0.67 0.361 0.13 1.56 1.577 0.9292 3044164 ChemDiv3_016466 CC1CN(C(=O)C)c2ccc(cc2O1)S(=O)(=O)N(CC=C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M11 compound treatment 0.21 -0.00706 -0.07 0.243 0.0123 0.15 0.0515 0.3126 3125005 ChemDiv3_016467 CCc1cccc(NC(=O)CCS(=O)(=O)c2ccc3NC(=O)CSc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M12 compound treatment 0.229 0.0119 0.13 0.305 0.0743 0.89 0.7171 0.7989 3125006 ChemDiv3_016468 COC(=O)c1ccccc1NS(=O)(=O)c2c(C)nc3sccn3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M13 compound treatment 0.257 0.0399 0.42 0.3 0.0693 0.83 0.8827 0.9502 3044167 ChemDiv3_016469 COc1ccc(CNC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M14 compound treatment 0.24 0.0229 0.24 0.313 0.0823 0.98 0.8665 0.8549 3125007 ChemDiv3_016470 CC1CC(C)CN(C1)C(=O)NCc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M15 compound treatment 0.217 -6.25E-5 0.0 0.252 0.0213 0.25 0.1796 0.7053 3044203 ChemDiv3_016471 COC(=O)c1cc(c[nH]1)S(=O)(=O)N2C(C)Cc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M16 compound treatment 0.133 -0.0841 -0.88 0.199 -0.0317 -0.38 -0.8926 -0.9289 3044204 ChemDiv3_016472 CC1CCCC(C)N1CCCNC(=O)NCc2noc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M17 compound treatment 0.276 0.0589 0.62 0.306 0.0753 0.9 1.0746 0.9833 3044206 ChemDiv3_016473 Cc1ccsc1CCNC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M18 compound treatment 0.2 -0.0171 -0.18 0.246 0.0153 0.18 0.0026 0.01 3044208 ChemDiv3_016474 COc1cc(Cl)c(C)cc1NC(=O)NCc2noc3ccc(C)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M19 compound treatment 0.204 -0.0131 -0.14 0.213 -0.0177 -0.21 -0.2469 -0.9778 3044209 ChemDiv3_016475 CSc1ccc(CCNCc2c(C(=O)O)n(C)c3cc(C)ccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M20 compound treatment 0.201 -0.0161 -0.17 0.249 0.0183 0.22 0.0354 0.1281 3044210 ChemDiv3_016476 CCC1Sc2cc(ccc2NC1=O)S(=O)(=O)CCC(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M21 compound treatment 0.228 0.0109 0.11 0.232 0.00128 0.02 0.0921 0.7944 3125008 ChemDiv3_016477 Cc1ccc(NC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M22 compound treatment 0.429 0.212 2.23 0.552 0.321 3.84 4.292 0.9663 3125009 ChemDiv3_016478 CCC1Sc2cc(ccc2NC1=O)S(=O)(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M23 mock treatment 0.185 -0.0321 -0.34 0.206 -0.0247 -0.3 -0.4472 -0.9979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 M24 mock treatment 0.195 -0.0221 -0.23 0.262 0.0313 0.37 0.1008 0.229 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N01 compound treatment 0.176 -0.0411 -0.43 0.207 -0.0237 -0.28 -0.5056 -0.9794 3044213 ChemDiv3_016479 CCn1c(=O)c2sccc2n3c(CCCC(=O)NCCc4ccccc4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N02 compound treatment 0.133 -0.0841 -0.88 0.174 -0.0567 -0.68 -1.1041 -0.9916 3125010 ChemDiv3_016480 Cn1cc(NC(=O)N(CC2CCCO2)Cc3ccco3)c4ccccc4c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N03 compound treatment 0.216 -0.00106 -0.01 0.291 0.0603 0.72 0.5021 0.6961 3044215 ChemDiv3_016481 CC(C)NC(=O)c1nc(c2cccc(F)c2)n3CCCCCc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N04 compound treatment 0.142 -0.0751 -0.79 0.188 -0.0427 -0.51 -0.9189 -0.978 3125011 ChemDiv3_016482 Fc1ccccc1C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N05 compound treatment 0.147 -0.0701 -0.74 0.16 -0.0707 -0.85 -1.1186 -0.9976 3125012 ChemDiv3_016483 CCN1CCN(CC1)C(=O)C2CCCN(C2)c3nn4cc(nc4s3)c5ccc(OC)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N06 compound treatment 0.162 -0.0551 -0.58 0.208 -0.0227 -0.27 -0.6011 -0.9407 3044217 ChemDiv3_016484 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N07 compound treatment 0.285 0.0679 0.71 0.328 0.0973 1.16 1.3276 0.9724 3125013 ChemDiv3_016485 CCOc1ccc(CCNC(=O)c2cn3CC(C)Oc4ccc(Cl)c(c2=O)c43)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N08 compound treatment 0.228 0.0109 0.11 0.264 0.0333 0.4 0.3628 0.8754 3044219 ChemDiv3_016486 Clc1ccc(cc1)c2nc(C(=O)NC3CCCC3)c4CCCCCn24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N09 compound treatment 0.148 -0.0691 -0.73 0.14 -0.0907 -1.09 -1.2804 -0.9808 3125014 ChemDiv3_016487 CCOC(=O)c1ccccc1NC(=O)N2CCC(CN3CCCC3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N10 compound treatment 0.37 0.153 1.61 0.44 0.209 2.5 2.9063 0.977 3044221 ChemDiv3_016488 COc1ccc(cc1OC)c2noc(n2)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N11 compound treatment 0.201 -0.0161 -0.17 0.277 0.0463 0.55 0.2723 0.4703 3125015 ChemDiv3_016489 CCC(NC(=O)Nc1cc(C)cc(C)c1)c2c(sc3CN(CC)CCc23)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N12 compound treatment 0.125 -0.0921 -0.97 0.142 -0.0887 -1.06 -1.4343 -0.9989 3044223 ChemDiv3_016490 Fc1ccc(NC(=O)Cn2ncc3c4ccccc4[nH]c3c2=O)c(F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N13 compound treatment 0.162 -0.0551 -0.58 0.217 -0.0137 -0.16 -0.525 -0.8733 3125016 ChemDiv3_016491 CCC(Sc1nc2cccnc2[nH]1)C(=O)N(CC)c3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N14 compound treatment 0.156 -0.0611 -0.64 0.205 -0.0257 -0.31 -0.6711 -0.9434 3125017 ChemDiv3_016492 CC1CCN(CC1)S(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N15 compound treatment 0.203 -0.0141 -0.15 0.226 -0.00472 -0.06 -0.1444 -0.913 3044260 ChemDiv3_016493 Cc1ccc2Oc3ncccc3C(=O)N(CC(=O)NCCc4ccccc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N16 compound treatment 0.162 -0.0551 -0.58 0.198 -0.0327 -0.39 -0.6857 -0.9819 3044262 ChemDiv3_016494 Cc1cc2n(C)c(=O)c(=O)n(C)c2cc1S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N17 compound treatment 0.341 0.124 1.3 0.383 0.152 1.82 2.2087 0.9864 3044264 ChemDiv3_016495 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N18 compound treatment 0.181 -0.0361 -0.38 0.213 -0.0177 -0.21 -0.4177 -0.9624 3044266 ChemDiv3_016496 O=C1N(CCc2ccc(cc2)S(=O)(=O)N3CCCC3)C(=O)c4ncccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N19 compound treatment 0.178 -0.0391 -0.41 0.211 -0.0197 -0.24 -0.4569 -0.9655 3044267 ChemDiv3_016497 O=S(=O)(N1CCCCC1)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N20 compound treatment 0.795 0.578 6.07 0.817 0.586 7.01 9.2521 0.9974 3044269 ChemDiv3_016498 CC1CCCCN1S(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N21 compound treatment 0.13 -0.0871 -0.91 0.154 -0.0767 -0.92 -1.2956 -1.0 3044270 ChemDiv3_016499 CCN(CCCNc1nc(no1)c2cc(OC)ccc2OC)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N22 compound treatment 0.65 0.433 4.55 0.725 0.494 5.91 7.3969 0.9916 3125018 ChemDiv3_016500 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)n3cccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N23 mock treatment 0.209 -0.00806 -0.08 0.191 -0.0397 -0.48 -0.3959 -0.8202 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 N24 mock treatment 0.187 -0.0301 -0.32 0.242 0.0113 0.13 -0.1278 -0.3722 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O01 compound treatment 0.254 0.0369 0.39 0.326 0.0953 1.14 1.0804 0.8972 3044273 ChemDiv3_016501 COc1cccc(c1)n2cc(C(=O)NCCC(C)C)c3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O02 compound treatment 0.207 -0.0101 -0.11 0.233 0.00228 0.03 -0.0554 -0.5078 3125019 ChemDiv3_016502 O=C(CCC(=O)N1CCSc2ccccc12)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O03 compound treatment 0.212 -0.00506 -0.05 0.253 0.0223 0.27 0.1509 0.5551 3125020 ChemDiv3_016503 COc1cccc(c1)n2cc(C(=O)N(Cc3ccccc3)C(C)C)c4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O04 compound treatment 0.237 0.0199 0.21 0.278 0.0473 0.57 0.5481 0.9086 3044276 ChemDiv3_016504 CCn1cc(CCC(=O)NC(C)c2ccccc2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O05 compound treatment 0.305 0.0879 0.92 0.297 0.0663 0.79 1.2138 0.9971 3125021 ChemDiv3_016505 CCOc1ccccc1N(C)S(=O)(=O)c2ccc3NC(=O)C(C)Sc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O06 compound treatment 0.913 0.696 7.31 1.074 0.843 10.09 12.3027 0.9875 3044278 ChemDiv3_016506 CNC(=O)CCc1cn(Cc2ccc(C)cc2)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O07 compound treatment 0.24 0.0229 0.24 0.256 0.0253 0.3 0.3842 0.9936 3125022 ChemDiv3_016507 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NC4CCCc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O08 compound treatment 0.358 0.141 1.48 0.4 0.169 2.03 2.4788 0.9881 3125023 ChemDiv3_016508 COc1ccc(cc1)c2noc(CC(=O)N3CCCCCC3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O09 compound treatment 1.11 0.893 9.38 1.144 0.913 10.93 14.3579 0.9971 3044281 ChemDiv3_016509 Cc1ccc(cc1)c2nc(C(=O)Nc3ccc(Cl)cc3)c4CCCCCn24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O10 compound treatment 0.184 -0.0331 -0.35 0.225 -0.00572 -0.07 -0.2939 -0.8305 3125024 ChemDiv3_016510 CC(C)C(NS(=O)(=O)c1ccc2N(C)C(=O)C(C)(C)c2c1)C(=O)NCc3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O11 compound treatment 0.165 -0.0521 -0.55 0.187 -0.0437 -0.52 -0.7565 -0.9998 3044283 ChemDiv3_016511 O=C(CCS(=O)(=O)c1ccc2NC(=O)CSc2c1)NCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O12 compound treatment 0.153 -0.0641 -0.67 0.195 -0.0357 -0.43 -0.7779 -0.976 3044335 ChemDiv3_016512 Cc1nc2sccn2c(=O)c1S(=O)(=O)NC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O13 compound treatment 0.176 -0.0411 -0.43 0.2 -0.0307 -0.37 -0.5648 -0.9968 3044336 ChemDiv3_016513 O=C(N1CCCC1)c2cc(c[nH]2)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O14 compound treatment 0.171 -0.0461 -0.48 0.169 -0.0617 -0.74 -0.8642 -0.979 3044338 ChemDiv3_016514 CCN(CC)C(=O)NCc1noc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O15 compound treatment 0.342 0.125 1.31 0.492 0.261 3.13 3.1383 0.9257 3044340 ChemDiv3_016515 CCN(Cc1ccccc1)S(=O)(=O)c2c[nH]c(c2)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O16 compound treatment 0.257 0.0399 0.42 0.323 0.0923 1.1 1.0773 0.9121 3044341 ChemDiv3_016516 CC(NC(=O)NCc1noc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O17 compound treatment 0.166 -0.0511 -0.54 0.232 0.00128 0.02 -0.3684 -0.6866 3044342 ChemDiv3_016517 CCc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)N3CCOCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O18 compound treatment 0.2 -0.0171 -0.18 0.236 0.00528 0.06 -0.082 -0.4317 3044343 ChemDiv3_016518 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N(C)CC(=O)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O19 compound treatment 0.208 -0.00906 -0.1 0.243 0.0123 0.15 0.0366 0.209 3125025 ChemDiv3_016519 CCn1c(C(=O)O)c(CNCc2cccc(Cl)c2)c3ccc(C)cc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O20 compound treatment 0.187 -0.0301 -0.32 0.229 -0.00172 -0.02 -0.2378 -0.7516 3044345 ChemDiv3_016520 COc1cc(NC(=O)CN2C(=O)COc3cc(ccc23)S(=O)(=O)N4CCOCC4)cc(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O21 compound treatment 0.2 -0.0171 -0.18 0.239 0.00828 0.1 -0.0567 -0.2767 3125026 ChemDiv3_016521 COc1ccccc1NC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O22 compound treatment 0.262 0.0449 0.47 0.313 0.0823 0.98 1.0298 0.9433 3125027 ChemDiv3_016522 CN(CC(=O)Nc1nc2ccc(Cl)cc2s1)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O23 mock treatment 0.188 -0.0291 -0.31 0.168 -0.0627 -0.75 -0.7464 -0.9214 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 O24 mock treatment 0.221 0.00394 0.04 0.205 -0.0257 -0.31 -0.1883 -0.6066 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P01 compound treatment 0.184 -0.0331 -0.35 0.178 -0.0527 -0.63 -0.6915 -0.9605 3044348 ChemDiv3_016523 CC(C)Cn1c(=O)c2sccc2n3c(CCCC(=O)NC4CCCCCC4)nnc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P02 compound treatment 0.15 -0.0671 -0.7 0.175 -0.0557 -0.67 -0.9694 -0.9996 3125137 ChemDiv3_016524 CSc1ccc(CCNC(=O)Nc2cn(C)c(=O)c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P03 compound treatment 0.226 0.00894 0.09 0.218 -0.0127 -0.15 -0.0412 -0.2306 3044350 ChemDiv3_016525 CN(C(=O)c1nc(c2cccc(F)c2)n3CCCCCc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P04 compound treatment 0.164 -0.0531 -0.56 0.177 -0.0537 -0.64 -0.8485 -0.9975 3125138 ChemDiv3_016526 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P05 compound treatment 0.099 -0.118 -1.24 0.095 -0.136 -1.62 -2.025 -0.9911 3125139 ChemDiv3_016527 CNC(=O)C1CCCN(C1)c2nn3cc(nc3s2)c4ccc(OC)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P06 compound treatment 0.198 -0.0191 -0.2 0.162 -0.0687 -0.82 -0.7229 -0.8543 3044352 ChemDiv3_016528 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P07 compound treatment 0.089 -0.128 -1.34 0.085 -0.146 -1.74 -2.1839 -0.9918 3125140 ChemDiv3_016529 COc1ccc(NC(=O)N2CCC(CN3CCCCC3)CC2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P08 compound treatment 0.266 0.0489 0.51 0.256 0.0253 0.3 0.5773 0.968 3044354 ChemDiv3_016530 CCCNC(=O)c1nc(c2ccc(Cl)cc2)n3CCCCCc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P09 compound treatment 0.16 -0.0571 -0.6 0.172 -0.0587 -0.7 -0.9205 -0.9969 3125141 ChemDiv3_016531 COC(=O)c1ccccc1NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P10 compound treatment 0.146 -0.0711 -0.75 0.136 -0.0947 -1.13 -1.3291 -0.9795 3125142 ChemDiv3_016532 CCc1ccccc1NC(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P11 compound treatment 0.163 -0.0541 -0.57 0.159 -0.0717 -0.86 -1.0082 -0.9799 3044356 ChemDiv3_016533 CCN1CCC(CC1)N(Cc2ccco2)C(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P12 compound treatment 0.265 0.0479 0.5 0.297 0.0663 0.79 0.9168 0.976 3044358 ChemDiv3_016534 CSc1ncc(C(=O)NCc2ccccc2)c(C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P13 compound treatment 0.266 0.0489 0.51 0.302 0.0713 0.85 0.9665 0.9706 3125143 ChemDiv3_016535 Fc1ccc(CSc2nc3cccnc3n2CC(=O)N4CCCc5ccccc45)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P14 compound treatment 0.173 -0.0441 -0.46 0.166 -0.0647 -0.77 -0.8748 -0.9697 3044412 ChemDiv3_016536 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)N3CCc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P15 compound treatment 0.247 0.0299 0.31 0.233 0.00228 0.03 0.2416 0.7656 3044414 ChemDiv3_016537 CC1CCCC(NC(=O)CN2C(=O)c3cccnc3Oc4ccc(C)cc24)C1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P16 compound treatment 0.147 -0.0701 -0.74 0.156 -0.0747 -0.89 -1.1525 -0.9953 3044416 ChemDiv3_016538 Cc1cc2n(C)c(=O)c(=O)n(C)c2cc1S(=O)(=O)NCC3CCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P17 compound treatment 0.268 0.0509 0.53 0.261 0.0303 0.36 0.6345 0.982 3044417 ChemDiv3_016539 Fc1ccccc1NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P18 compound treatment 0.624 0.407 4.27 0.696 0.465 5.57 6.9585 0.9915 3044419 ChemDiv3_016540 CN(C1CCCCC1)S(=O)(=O)c2ccc(CCN3C(=O)c4cccnc4C3=O)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P19 compound treatment 0.475 0.258 2.71 0.468 0.237 2.84 3.923 0.9997 3044420 ChemDiv3_016541 O=S(=O)(Nc1ccc(cc1)c2ccno2)c3ccc4[nH]c5CCCCc5c4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P20 compound treatment 0.206 -0.0111 -0.12 0.236 0.00528 0.06 -0.0375 -0.2834 3125144 ChemDiv3_016542 O=C1N(Cc2ccc(cc2)S(=O)(=O)NCc3ccccc3)C(=O)c4ncccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P21 compound treatment 1.064 0.847 8.9 1.074 0.843 10.09 13.4241 0.998 3044422 ChemDiv3_016543 COc1ccc(OC)c(c1)c2noc(NCCc3ccc(Cl)cc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P22 compound treatment 0.621 0.404 4.24 0.735 0.504 6.03 7.2661 0.9851 3125145 ChemDiv3_016544 O=S(=O)(N1CCCC2CCCCC21)c3ccc(cc3)n4cccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P23 mock treatment 0.211 -0.00606 -0.06 0.218 -0.0127 -0.15 -0.1526 -0.9252 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2047 P24 mock treatment 0.187 -0.0301 -0.32 0.2 -0.0307 -0.37 -0.4831 -0.9971 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A01 compound treatment 0.267 -0.0147 -0.15 0.218 -8.8E-5 0.0 -0.1097 -0.7119 3044425 ChemDiv3_016545 Cc1cccc(NS(=O)(=O)c2ccc(cc2)n3cccn3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A02 compound treatment 0.349 0.0673 0.71 0.275 0.0569 0.68 0.9815 0.9998 3125146 ChemDiv3_016546 CCc1cccc(NS(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A03 compound treatment 0.223 -0.0587 -0.62 0.181 -0.0371 -0.44 -0.7495 -0.987 3125147 ChemDiv3_016547 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)CCC(=O)Nc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A04 compound treatment 0.219 -0.0627 -0.66 0.171 -0.0471 -0.56 -0.8638 -0.997 3044427 ChemDiv3_016548 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)NC(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A05 compound treatment 0.33 0.0483 0.51 0.293 0.0749 0.9 0.9927 0.9637 3044429 ChemDiv3_016549 Cc1ccccc1NS(=O)(=O)c2cc(F)ccc2CN3C(=O)c4cccnc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A06 mock treatment 0.223 -0.0587 -0.62 0.17 -0.0481 -0.58 -0.8426 -0.9994 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A07 compound treatment 0.214 -0.0677 -0.71 0.158 -0.0601 -0.72 -1.0109 -1.0 3044490 ChemDiv3_016550 Brc1ccc(cc1)N2CC(=O)Nc3ccccc3S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A08 mock treatment 0.202 -0.0797 -0.84 0.159 -0.0591 -0.71 -1.0916 -0.9965 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A09 compound treatment 0.184 -0.0977 -1.03 0.151 -0.0671 -0.8 -1.293 -0.9926 3125148 ChemDiv3_016551 Cc1ccc(CNC(=O)CN2C=NS(=O)(=O)c3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A10 mock treatment 0.228 -0.0537 -0.56 0.14 -0.0781 -0.93 -1.0593 -0.9707 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A11 compound treatment 0.212 -0.0697 -0.73 0.158 -0.0601 -0.72 -1.0258 -1.0 3125149 ChemDiv3_016552 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)NCc4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A12 mock treatment 0.187 -0.0947 -0.99 0.145 -0.0731 -0.87 -1.3214 -0.9979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A13 compound treatment 0.269 -0.0127 -0.13 0.229 0.0109 0.13 -0.0018 -0.0097 3044432 ChemDiv3_016553 CC1(C)CC(=O)N(CC(=O)NCc2cccs2)c3ccccc3S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A14 mock treatment 0.223 -0.0587 -0.62 0.158 -0.0601 -0.72 -0.9441 -0.9971 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A15 compound treatment 0.18 -0.102 -1.07 0.158 -0.0601 -0.72 -1.2634 -0.9815 3125150 ChemDiv3_016554 CC(C)CCNC(=O)C1CCC(=O)N1C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A16 mock treatment 0.22 -0.0617 -0.65 0.168 -0.0501 -0.6 -0.8818 -0.9992 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A17 compound treatment 0.189 -0.0927 -0.97 0.147 -0.0711 -0.85 -1.2897 -0.9977 3044434 ChemDiv3_016555 CCC(C)N1C(CCC1=O)C(=O)NCc2ccc3OCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A18 mock treatment 0.257 -0.0247 -0.26 0.213 -0.00509 -0.06 -0.2263 -0.8501 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A19 compound treatment 0.261 -0.0207 -0.22 0.191 -0.0271 -0.32 -0.3827 -0.981 3125151 ChemDiv3_016556 O=C(NCCCN1CCCC1)C2CCC(=O)N2C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A20 mock treatment 0.227 -0.0547 -0.57 0.222 0.00391 0.05 -0.3729 -0.6473 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A21 compound treatment 0.252 -0.0297 -0.31 0.189 -0.0291 -0.35 -0.4665 -0.9985 3044491 ChemDiv3_016557 Clc1ccccc1CN2C(CCC2=O)C(=O)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A22 mock treatment 0.27 -0.0117 -0.12 0.211 -0.00709 -0.08 -0.1467 -0.9838 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A23 mock treatment 0.242 -0.0397 -0.42 0.189 -0.0291 -0.35 -0.5407 -0.996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 A24 mock treatment 0.28 -0.00167 -0.02 0.256 0.0379 0.45 0.3083 0.6792 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B01 mock treatment 0.265 -0.0167 -0.18 0.21 -0.00809 -0.1 -0.1923 -0.9609 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B02 mock treatment 0.271 -0.0107 -0.11 0.186 -0.0321 -0.38 -0.3507 -0.877 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B03 mock treatment 0.214 -0.0677 -0.71 0.196 -0.0221 -0.26 -0.6895 -0.9092 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B04 mock treatment 0.214 -0.0677 -0.71 0.27 0.0519 0.62 -0.0634 -0.0672 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B05 mock treatment 0.27 -0.0117 -0.12 0.221 0.00291 0.03 -0.0621 -0.4869 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B06 mock treatment 0.239 -0.0427 -0.45 0.162 -0.0561 -0.67 -0.7914 -0.9807 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B07 mock treatment 0.222 -0.0597 -0.63 0.168 -0.0501 -0.6 -0.8669 -0.9997 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B08 mock treatment 0.225 -0.0567 -0.6 0.151 -0.0671 -0.8 -0.9885 -0.9892 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B09 mock treatment 0.244 -0.0377 -0.4 0.225 0.00691 0.08 -0.2213 -0.5475 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B10 mock treatment 0.232 -0.0497 -0.52 0.236 0.0179 0.21 -0.2174 -0.3854 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B11 mock treatment 0.293 0.0113 0.12 0.228 0.00991 0.12 0.168 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B12 mock treatment 0.178 -0.104 -1.09 0.163 -0.0551 -0.66 -1.236 -0.9711 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B13 mock treatment 0.232 -0.0497 -0.52 0.176 -0.0421 -0.5 -0.725 -0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B14 mock treatment 0.247 -0.0347 -0.36 0.159 -0.0591 -0.71 -0.7574 -0.9524 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B15 mock treatment 0.304 0.0223 0.23 0.211 -0.00709 -0.08 0.1058 0.4245 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B16 mock treatment 0.308 0.0263 0.28 0.18 -0.0381 -0.46 -0.1267 -0.2378 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B17 mock treatment 0.289 0.00733 0.08 0.197 -0.0211 -0.25 -0.124 -0.4701 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B18 mock treatment 0.262 -0.0197 -0.21 0.166 -0.0521 -0.62 -0.5868 -0.8937 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B19 mock treatment 0.294 0.0123 0.13 0.199 -0.0191 -0.23 -0.07 -0.2665 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B20 mock treatment 0.34 0.0583 0.61 0.243 0.0249 0.3 0.6439 0.9452 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B21 mock treatment 0.305 0.0233 0.24 0.2 -0.0181 -0.22 0.0202 0.0618 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B22 mock treatment 0.281 -6.75E-4 -0.01 0.237 0.0189 0.23 0.155 0.6846 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B23 mock treatment 0.256 -0.0257 -0.27 0.189 -0.0291 -0.35 -0.4368 -0.992 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 B24 mock treatment 0.252 -0.0297 -0.31 0.206 -0.0121 -0.14 -0.3226 -0.9391 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C01 compound treatment 0.212 -0.0697 -0.73 0.191 -0.0271 -0.32 -0.7466 -0.9329 3044493 ChemDiv3_016558 CCc1cccc(NC(=O)CN2C(=O)COc3cc(ccc23)S(=O)(=O)Nc4ccccc4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C02 compound treatment 0.272 -0.00967 -0.1 0.215 -0.00309 -0.04 -0.098 -0.9062 3044494 ChemDiv3_016559 CC1CC(C)CN(C1)C(=O)CN(C)S(=O)(=O)c2cc3OCC(=O)Nc3cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C03 compound treatment 0.233 -0.0487 -0.51 0.192 -0.0261 -0.31 -0.5822 -0.972 3044496 ChemDiv3_016560 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C04 compound treatment 0.391 0.109 1.15 0.287 0.0689 0.82 1.3949 0.9868 3044498 ChemDiv3_016561 Cc1nc2ccc(cc2o1)S(=O)(=O)NC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C05 compound treatment 0.512 0.23 2.42 0.415 0.197 2.36 3.3764 0.9999 3044499 ChemDiv3_016562 CC(C)(C)NC(=O)c1cc(n[nH]1)c2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C06 mock treatment 0.249 -0.0327 -0.34 0.213 -0.00509 -0.06 -0.2857 -0.8197 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C07 compound treatment 0.243 -0.0387 -0.41 0.192 -0.0261 -0.31 -0.5079 -0.9915 3125152 ChemDiv3_016563 COc1ccccc1NC(=O)CN2C=NS(=O)(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C08 mock treatment 0.234 -0.0477 -0.5 0.186 -0.0321 -0.38 -0.6255 -0.9914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C09 compound treatment 0.256 -0.0257 -0.27 0.205 -0.0131 -0.16 -0.3014 -0.9666 3044501 ChemDiv3_016564 Cc1ccc(cc1)N2C(=O)N(CC(=O)c3ccccc3)c4ccccc4S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C10 mock treatment 0.298 0.0163 0.17 0.165 -0.0531 -0.64 -0.3279 -0.4984 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C11 compound treatment 0.325 0.0433 0.46 0.221 0.00291 0.03 0.3464 0.759 3125153 ChemDiv3_016565 COc1ccc(CCNC(=O)c2ccc3c(=O)n4nc(C)sc4nc3c2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C12 mock treatment 0.291 0.00933 0.1 0.189 -0.0291 -0.35 -0.1768 -0.4891 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C13 compound treatment 0.924 0.642 6.75 0.735 0.517 6.18 9.1434 0.9991 3044503 ChemDiv3_016566 CN1CCSc2ccc(cc12)C(=O)Nc3ccc(Br)c(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C14 mock treatment 0.221 -0.0607 -0.64 0.173 -0.0451 -0.54 -0.8321 -0.9966 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C15 compound treatment 0.209 -0.0727 -0.76 0.159 -0.0591 -0.71 -1.0396 -0.9993 3125154 ChemDiv3_016567 CC(C)N1C(CCC1=O)C(=O)N2CCC3(CC2)OCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C16 mock treatment 0.216 -0.0657 -0.69 0.184 -0.0341 -0.41 -0.7761 -0.9686 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C17 compound treatment 0.262 -0.0197 -0.21 0.182 -0.0361 -0.43 -0.4514 -0.9431 3125155 ChemDiv3_016568 CCOC(=O)N1CCC(CC1)NC(=O)CN2C(=O)C(CC)Oc3ccc(C)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C18 mock treatment 0.277 -0.00467 -0.05 0.201 -0.0171 -0.2 -0.1793 -0.8527 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C19 compound treatment 0.621 0.339 3.56 0.457 0.239 2.86 4.5412 0.994 3044505 ChemDiv3_016569 COc1ccc(CN2CC(CC2=O)C(=O)NCc3ccccn3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C20 mock treatment 0.24 -0.0417 -0.44 0.197 -0.0211 -0.25 -0.4879 -0.9657 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C21 compound treatment 0.283 0.00133 0.01 0.191 -0.0271 -0.32 -0.2193 -0.6761 3125156 ChemDiv3_016570 COC(CN(C)C(=O)CN1CCN(Cc2ccc(Cl)cc2)C1=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C22 mock treatment 0.276 -0.00567 -0.06 0.208 -0.0101 -0.12 -0.1275 -0.9471 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C23 mock treatment 0.249 -0.0327 -0.34 0.203 -0.0151 -0.18 -0.3703 -0.955 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 C24 mock treatment 0.281 -6.75E-4 -0.01 0.263 0.0449 0.54 0.3749 0.6977 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D01 mock treatment 0.243 -0.0387 -0.41 0.188 -0.0301 -0.36 -0.5418 -0.9982 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D02 mock treatment 0.226 -0.0557 -0.58 0.167 -0.0511 -0.61 -0.8457 -0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D03 mock treatment 0.331 0.0493 0.52 0.17 -0.0481 -0.58 -0.0405 -0.0523 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D04 mock treatment 0.338 0.0563 0.59 0.2 -0.0181 -0.22 0.2653 0.4211 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D05 mock treatment 0.272 -0.00967 -0.1 0.229 0.0109 0.13 0.0205 0.1237 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D06 mock treatment 0.267 -0.0147 -0.15 0.237 0.0189 0.23 0.051 0.1863 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D07 mock treatment 0.298 0.0163 0.17 0.214 -0.00409 -0.05 0.0867 0.486 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D08 mock treatment 0.255 -0.0267 -0.28 0.172 -0.0461 -0.55 -0.588 -0.9507 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D09 mock treatment 0.311 0.0293 0.31 0.278 0.0599 0.72 0.7246 0.9288 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D10 mock treatment 0.309 0.0273 0.29 0.253 0.0349 0.42 0.4983 0.9832 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D11 mock treatment 0.309 0.0273 0.29 0.243 0.0249 0.3 0.4137 0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D12 mock treatment 0.312 0.0303 0.32 0.307 0.0889 1.06 0.9774 0.8802 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D13 mock treatment 0.334 0.0523 0.55 0.255 0.0369 0.44 0.7009 0.9941 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D14 mock treatment 0.315 0.0333 0.35 0.211 -0.00709 -0.08 0.1875 0.5207 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D15 mock treatment 0.32 0.0383 0.4 0.256 0.0379 0.45 0.6054 0.9982 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D16 mock treatment 0.336 0.0543 0.57 0.205 -0.0131 -0.16 0.2927 0.4947 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D17 mock treatment 0.31 0.0283 0.3 0.186 -0.0321 -0.38 -0.0611 -0.1258 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D18 mock treatment 0.298 0.0163 0.17 0.244 0.0259 0.31 0.3405 0.961 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D19 mock treatment 0.349 0.0673 0.71 0.173 -0.0451 -0.54 0.1185 0.1333 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D20 mock treatment 0.319 0.0373 0.39 0.22 0.00191 0.02 0.2934 0.7471 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D21 mock treatment 0.318 0.0363 0.38 0.207 -0.0111 -0.13 0.176 0.4356 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D22 mock treatment 0.308 0.0263 0.28 0.241 0.0229 0.27 0.3893 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D23 mock treatment 0.272 -0.00967 -0.1 0.205 -0.0131 -0.16 -0.1826 -0.9781 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 D24 mock treatment 0.25 -0.0317 -0.33 0.238 0.0199 0.24 -0.0668 -0.1632 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E01 compound treatment 0.141 -0.141 -1.48 0.139 -0.0791 -0.95 -1.7138 -0.9768 3044506 ChemDiv3_016571 O=C(NCc1ccccc1)c2ccc(cc2)n3cnc4cccnc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E02 compound treatment 0.291 0.00933 0.1 0.219 9.12E-4 0.01 0.077 0.7811 3125157 ChemDiv3_016572 CN(CC(=O)Nc1ccc(C)c(F)c1)c2cc3OCC(=O)Nc3cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E03 compound treatment 0.579 0.297 3.12 0.746 0.528 6.32 6.6743 0.9473 3044508 ChemDiv3_016573 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)N3CCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E04 compound treatment 0.296 0.0143 0.15 0.212 -0.00609 -0.07 0.0549 0.3283 3125158 ChemDiv3_016574 O=C(NCc1ccc(s1)S(=O)(=O)N2CCOCC2)c3cccnc3C(=O)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E05 compound treatment 0.497 0.215 2.26 0.381 0.163 1.95 2.9774 0.9973 3125159 ChemDiv3_016575 CC(CNC(=O)c1cc(n[nH]1)c2ccco2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E06 mock treatment 0.255 -0.0267 -0.28 0.224 0.00591 0.07 -0.1481 -0.5125 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E07 compound treatment 0.252 -0.0297 -0.31 0.173 -0.0451 -0.54 -0.6018 -0.966 3044510 ChemDiv3_016576 CCCCN1C=NS(=O)(=O)c2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E08 mock treatment 0.258 -0.0237 -0.25 0.184 -0.0341 -0.41 -0.4642 -0.9718 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E09 compound treatment 0.232 -0.0497 -0.52 0.201 -0.0171 -0.2 -0.5135 -0.9164 3044511 ChemDiv3_016577 Cc1ccc(C)c(c1)N2C(=O)Nc3ccccc3S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E10 mock treatment 0.281 -6.75E-4 -0.01 0.183 -0.0351 -0.42 -0.3019 -0.7189 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E11 compound treatment 0.128 -0.154 -1.61 0.115 -0.103 -1.23 -2.0134 -0.9912 3125160 ChemDiv3_016578 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)N4CCN(CC4)c5ccc(F)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E12 mock treatment 0.27 -0.0117 -0.12 0.193 -0.0251 -0.3 -0.299 -0.922 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E13 compound treatment 0.318 0.0363 0.38 0.189 -0.0291 -0.35 0.0237 0.0459 3125161 ChemDiv3_016579 CC(=O)Nc1ccccc1c2nc3ccc(cc3[nH]c2=O)C(=O)NCc4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E14 mock treatment 0.269 -0.0127 -0.13 0.168 -0.0501 -0.6 -0.5179 -0.8436 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E15 compound treatment 0.181 -0.101 -1.06 0.158 -0.0601 -0.72 -1.256 -0.9823 3044513 ChemDiv3_016580 CC(C)N1C(CCC1=O)C(=O)NCCC2=CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E16 mock treatment 0.283 0.00133 0.01 0.213 -0.00509 -0.06 -0.0332 -0.5317 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E17 compound treatment 0.276 -0.00567 -0.06 0.247 0.0289 0.35 0.2025 0.5768 3125162 ChemDiv3_016581 COc1ccc(Br)cc1CNC(=O)C2CCC(=O)N2C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E18 mock treatment 0.275 -0.00667 -0.07 0.214 -0.00409 -0.05 -0.0842 -0.9845 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E19 compound treatment 0.296 0.0143 0.15 0.212 -0.00609 -0.07 0.0549 0.3283 3044515 ChemDiv3_016582 O=C(C1CN(CCc2ccccc2)C(=O)C1)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E20 mock treatment 0.318 0.0363 0.38 0.207 -0.0111 -0.13 0.176 0.4356 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E21 compound treatment 0.104 -0.178 -1.87 0.107 -0.111 -1.33 -2.2593 -0.9862 3125163 ChemDiv3_016583 Cc1cc(Br)ccc1NC(=O)CCCc2c[nH]c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E22 mock treatment 0.268 -0.0137 -0.14 0.192 -0.0261 -0.31 -0.3223 -0.9379 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E23 mock treatment 0.285 0.00333 0.03 0.225 0.00691 0.08 0.0832 0.9265 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 E24 mock treatment 0.266 -0.0157 -0.16 0.221 0.00291 0.03 -0.0918 -0.5454 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F01 mock treatment 0.313 0.0313 0.33 0.181 -0.0371 -0.44 -0.0811 -0.1469 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F02 mock treatment 0.313 0.0313 0.33 0.194 -0.0241 -0.29 0.0288 0.066 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F03 mock treatment 0.276 -0.00567 -0.06 0.204 -0.0141 -0.17 -0.1613 -0.9024 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F04 mock treatment 0.274 -0.00767 -0.08 0.201 -0.0171 -0.2 -0.2016 -0.9172 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F05 mock treatment 0.304 0.0223 0.23 0.277 0.0589 0.7 0.6642 0.8942 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F06 mock treatment 0.282 3.25E-4 0.0 0.222 0.00391 0.05 0.0355 0.7567 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F07 mock treatment 0.299 0.0173 0.18 0.279 0.0609 0.73 0.644 0.8573 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F08 mock treatment 0.296 0.0143 0.15 0.249 0.0309 0.37 0.3679 0.9214 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F09 mock treatment 0.291 0.00933 0.1 0.259 0.0409 0.49 0.4154 0.8321 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F10 mock treatment 0.273 -0.00867 -0.09 0.223 0.00491 0.06 -0.0229 -0.2109 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F11 mock treatment 0.342 0.0603 0.63 0.231 0.0129 0.15 0.5572 0.8545 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F12 mock treatment 0.323 0.0413 0.43 0.264 0.0459 0.55 0.6953 0.9932 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F13 mock treatment 0.296 0.0143 0.15 0.272 0.0539 0.65 0.5625 0.8492 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F14 mock treatment 0.355 0.0733 0.77 0.261 0.0429 0.51 0.9076 0.9806 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F15 mock treatment 0.339 0.0573 0.6 0.256 0.0379 0.45 0.7465 0.9903 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F16 mock treatment 0.267 -0.0147 -0.15 0.193 -0.0251 -0.3 -0.3212 -0.952 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F17 mock treatment 0.364 0.0823 0.86 0.268 0.0499 0.6 1.0336 0.9837 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F18 mock treatment 0.338 0.0563 0.59 0.287 0.0689 0.82 1.0013 0.9867 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F19 mock treatment 0.391 0.109 1.15 0.253 0.0349 0.42 1.1073 0.9062 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F20 mock treatment 0.286 0.00433 0.05 0.221 0.00291 0.03 0.0568 0.9914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F21 mock treatment 0.326 0.0443 0.47 0.215 -0.00309 -0.04 0.3031 0.6489 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F22 mock treatment 0.292 0.0103 0.11 0.212 -0.00609 -0.07 0.0252 0.1927 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F23 mock treatment 0.249 -0.0327 -0.34 0.229 0.0109 0.13 -0.1503 -0.4095 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 F24 mock treatment 0.283 0.00133 0.01 0.233 0.0149 0.18 0.136 0.76 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G01 compound treatment 0.157 -0.125 -1.31 0.139 -0.0791 -0.95 -1.595 -0.9873 3044566 ChemDiv3_016584 O=C(NC1CCCCCC1)c2ccc(cc2)n3cnc4cccnc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G02 compound treatment 0.267 -0.0147 -0.15 0.209 -0.00909 -0.11 -0.1859 -0.9854 3044567 ChemDiv3_016585 CN(CC(=O)N1CCN(CC1)c2ccccc2F)c3cc4OCC(=O)Nc4cc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G03 compound treatment 0.141 -0.141 -1.48 0.126 -0.0921 -1.1 -1.8238 -0.9896 3044569 ChemDiv3_016586 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G04 compound treatment 0.306 0.0243 0.26 0.199 -0.0191 -0.23 0.0192 0.0559 3044570 ChemDiv3_016587 COC(=O)CN1C(=O)CSc2cc(ccc12)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G05 compound treatment 0.374 0.0923 0.97 0.328 0.11 1.32 1.6155 0.9888 3044572 ChemDiv3_016588 CCOC(=O)C1CCN(CC1)C(=O)c2cc(n[nH]2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G06 mock treatment 0.25 -0.0317 -0.33 0.195 -0.0231 -0.28 -0.4306 -0.9957 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G07 compound treatment 0.709 0.427 4.49 0.564 0.346 4.14 6.1 0.9992 3044573 ChemDiv3_016589 COc1ccc(cc1)N2C(=O)N(Cc3ccccc3)c4ccccc4S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G08 mock treatment 0.241 -0.0407 -0.43 0.195 -0.0231 -0.28 -0.4974 -0.9777 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G09 compound treatment 0.858 0.576 6.05 0.743 0.525 6.28 8.7209 0.9998 3044575 ChemDiv3_016590 Cc1cccc(c1)N2C(=O)N(Cc3ccccc3)c4ccccc4S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G10 mock treatment 0.265 -0.0167 -0.18 0.187 -0.0311 -0.37 -0.3868 -0.941 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G11 compound treatment 0.423 0.141 1.48 0.286 0.0679 0.81 1.6241 0.9598 3125164 ChemDiv3_016591 COc1ccc(Nc2nn3c(=O)c4ccccc4nc3s2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G12 mock treatment 0.216 -0.0657 -0.69 0.179 -0.0391 -0.47 -0.8184 -0.9821 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G13 compound treatment 0.381 0.0993 1.04 0.27 0.0519 0.62 1.1768 0.9693 3125276 ChemDiv3_016592 O=C(NC1CCCC1)C2N(Cc3ccccc3)C(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G14 mock treatment 0.299 0.0173 0.18 0.169 -0.0491 -0.59 -0.2866 -0.4662 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G15 compound treatment 0.283 0.00133 0.01 0.177 -0.0411 -0.49 -0.3378 -0.6868 3044577 ChemDiv3_016593 CC(C)N1C(CCC1=O)C(=O)N2CCCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G16 mock treatment 0.305 0.0233 0.24 0.225 0.00691 0.08 0.2317 0.8961 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G17 compound treatment 0.302 0.0203 0.21 0.227 0.00891 0.11 0.2263 0.9486 3125277 ChemDiv3_016594 CC(C)N1C(CCC1=O)C(=O)NCc2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G18 mock treatment 0.303 0.0213 0.22 0.192 -0.0261 -0.31 -0.0623 -0.1623 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G19 compound treatment 0.363 0.0813 0.85 0.2 -0.0181 -0.22 0.4509 0.5118 3125278 ChemDiv3_016595 COc1ccc(CCNC(=O)C2CCC(=O)N2CCc3ccccc3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G20 mock treatment 0.287 0.00533 0.06 0.171 -0.0471 -0.56 -0.3588 -0.6338 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G21 compound treatment 0.077 -0.205 -2.15 0.088 -0.13 -1.56 -2.6206 -0.9874 3044579 ChemDiv3_016596 Fc1cc(Cl)ccc1NC(=O)CCCc2c[nH]c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G22 mock treatment 0.291 0.00933 0.1 0.255 0.0369 0.44 0.3815 0.8434 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G23 mock treatment 0.267 -0.0147 -0.15 0.206 -0.0121 -0.14 -0.2112 -0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 G24 mock treatment 0.276 -0.00567 -0.06 0.232 0.0139 0.17 0.0756 0.4273 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H01 mock treatment 0.279 -0.00267 -0.03 0.162 -0.0561 -0.67 -0.4944 -0.7361 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H02 mock treatment 0.214 -0.0677 -0.71 0.175 -0.0431 -0.52 -0.8671 -0.9876 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H03 mock treatment 0.349 0.0673 0.71 0.197 -0.0211 -0.25 0.3216 0.4283 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H04 mock treatment 0.32 0.0383 0.4 0.192 -0.0261 -0.31 0.0639 0.1255 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H05 mock treatment 0.369 0.0873 0.92 0.237 0.0189 0.23 0.8085 0.8559 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H06 mock treatment 0.271 -0.0107 -0.11 0.231 0.0129 0.15 0.03 0.157 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H07 mock treatment 0.3 0.0183 0.19 0.254 0.0359 0.43 0.4399 0.9344 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H08 mock treatment 0.308 0.0263 0.28 0.22 0.00191 0.02 0.2117 0.763 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H09 mock treatment 0.301 0.0193 0.2 0.234 0.0159 0.19 0.2781 0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H10 mock treatment 0.338 0.0563 0.59 0.239 0.0209 0.25 0.5952 0.9267 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H11 mock treatment 0.317 0.0353 0.37 0.264 0.0459 0.55 0.6508 0.9817 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H12 mock treatment 0.264 -0.0177 -0.19 0.239 0.0209 0.25 0.0457 0.1465 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H13 mock treatment 0.433 0.151 1.59 0.303 0.0849 1.02 1.8422 0.9766 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H14 mock treatment 0.304 0.0223 0.23 0.26 0.0419 0.5 0.5204 0.9401 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H15 mock treatment 0.338 0.0563 0.59 0.255 0.0369 0.44 0.7306 0.9896 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H16 mock treatment 0.323 0.0413 0.43 0.23 0.0119 0.14 0.4077 0.8924 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H17 mock treatment 0.333 0.0513 0.54 0.279 0.0609 0.73 0.8965 0.989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H18 mock treatment 0.342 0.0603 0.63 0.237 0.0189 0.23 0.608 0.9037 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H19 mock treatment 0.362 0.0803 0.84 0.302 0.0839 1.0 1.3064 0.9963 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H20 mock treatment 0.3 0.0183 0.19 0.199 -0.0191 -0.23 -0.0254 -0.085 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H21 mock treatment 0.331 0.0493 0.52 0.22 0.00191 0.02 0.3825 0.7376 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H22 mock treatment 0.265 -0.0167 -0.18 0.172 -0.0461 -0.55 -0.5137 -0.888 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H23 mock treatment 0.365 0.0833 0.88 0.215 -0.00309 -0.04 0.5927 0.6767 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 H24 mock treatment 0.243 -0.0387 -0.41 0.203 -0.0151 -0.18 -0.4149 -0.9333 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I01 compound treatment 0.21 -0.0717 -0.75 0.174 -0.0441 -0.53 -0.9053 -0.9849 3125279 ChemDiv3_016597 O=C(NCC1CCCO1)c2ccc(cc2)n3cnc4cccnc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I02 compound treatment 0.478 0.196 2.06 0.355 0.137 1.64 2.6163 0.9935 3044580 ChemDiv3_016598 CN(CC(=O)N1CCc2ccccc2C1)c3cc4OCC(=O)Nc4cc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I03 compound treatment 0.366 0.0843 0.89 0.272 0.0539 0.65 1.0823 0.9879 3125280 ChemDiv3_016599 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)Nc3ccc(cc3)c4ccno4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I04 mock treatment 0.29 0.00833 0.09 0.246 0.0279 0.33 0.298 0.8631 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I05 compound treatment 0.252 -0.0297 -0.31 0.198 -0.0201 -0.24 -0.3903 -0.9918 3044582 ChemDiv3_016600 CCCNC(=O)c1cc(n[nH]1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I06 mock treatment 0.284 0.00233 0.02 0.249 0.0309 0.37 0.2788 0.7522 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I07 compound treatment 0.305 0.0233 0.24 0.293 0.0749 0.9 0.807 0.8685 3125281 ChemDiv3_016601 COc1ccccc1C(=O)CN2C=NS(=O)(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I08 mock treatment 0.306 0.0243 0.26 0.227 0.00891 0.11 0.256 0.9249 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I09 compound treatment 0.438 0.156 1.64 0.369 0.151 1.81 2.4377 0.9989 3125282 ChemDiv3_016602 COc1ccc(CNC(=O)c2ccc(CN3C(=NS(=O)(=O)c4ccccc34)C)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I10 mock treatment 0.257 -0.0247 -0.26 0.196 -0.0221 -0.26 -0.3701 -1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I11 compound treatment 0.669 0.387 4.07 0.636 0.418 5.0 6.4121 0.9948 1459368 ChemDiv3_016603 COc1cc2CCN(C(C)c2cc1OC)c3ncnc4n(ncc34)c5cccc(C)c5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I12 mock treatment 0.259 -0.0227 -0.24 0.183 -0.0351 -0.42 -0.4652 -0.9639 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I13 compound treatment 0.244 -0.0377 -0.4 0.196 -0.0221 -0.26 -0.4667 -0.9807 3125283 ChemDiv3_016604 O=C(NC1CCCC1)C2N(C3CCCC3)C(=O)c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I14 mock treatment 0.267 -0.0147 -0.15 0.197 -0.0211 -0.25 -0.2874 -0.972 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I15 compound treatment 0.233 -0.0487 -0.51 0.237 0.0189 0.23 -0.2015 -0.3604 3044585 ChemDiv3_016605 CCOC(=O)N1CCN(CC1)C(=O)C2CCC(=O)N2C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I16 mock treatment 0.312 0.0303 0.32 0.192 -0.0261 -0.31 0.0045 0.0101 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I17 compound treatment 0.276 -0.00567 -0.06 0.188 -0.0301 -0.36 -0.2967 -0.8131 3125284 ChemDiv3_016606 O=C(NC1CC1)C2CCC(=O)N2C3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I18 mock treatment 0.252 -0.0297 -0.31 0.228 0.00991 0.12 -0.1365 -0.4094 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I19 compound treatment 0.271 -0.0107 -0.11 0.211 -0.00709 -0.08 -0.1392 -0.9905 3125285 ChemDiv3_016607 O=C(NCc1cccnc1)C2CCC(=O)N2CCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I20 mock treatment 0.291 0.00933 0.1 0.198 -0.0201 -0.24 -0.1007 -0.388 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I21 compound treatment 0.485 0.203 2.14 0.358 0.14 1.67 2.6937 0.9927 3044587 ChemDiv3_016608 COc1ccc(NC(=O)CCCc2c[nH]c3ccccc23)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I22 mock treatment 0.287 0.00533 0.06 0.187 -0.0311 -0.37 -0.2235 -0.5941 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I23 mock treatment 0.234 -0.0477 -0.5 0.203 -0.0151 -0.18 -0.4817 -0.905 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 I24 mock treatment 0.284 0.00233 0.02 0.3 0.0819 0.98 0.7103 0.7245 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J01 mock treatment 0.25 -0.0317 -0.33 0.197 -0.0211 -0.25 -0.4136 -0.9907 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J02 mock treatment 0.244 -0.0377 -0.4 0.184 -0.0341 -0.41 -0.5682 -0.9999 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J03 mock treatment 0.352 0.0703 0.74 0.243 0.0249 0.3 0.733 0.9203 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J04 mock treatment 0.322 0.0403 0.42 0.274 0.0559 0.67 0.7725 0.9757 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J05 mock treatment 0.301 0.0193 0.2 0.256 0.0379 0.45 0.4643 0.9342 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J06 mock treatment 0.305 0.0233 0.24 0.272 0.0539 0.65 0.6293 0.9121 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J07 mock treatment 0.321 0.0393 0.41 0.209 -0.00909 -0.11 0.2152 0.5038 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J08 mock treatment 0.318 0.0363 0.38 0.246 0.0279 0.33 0.5059 0.9978 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J09 mock treatment 0.349 0.0673 0.71 0.257 0.0389 0.47 0.8292 0.9794 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J10 mock treatment 0.314 0.0323 0.34 0.247 0.0289 0.35 0.4847 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J11 mock treatment 0.401 0.119 1.25 0.264 0.0459 0.55 1.2746 0.9315 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J12 mock treatment 0.316 0.0343 0.36 0.215 -0.00309 -0.04 0.2288 0.6313 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J13 mock treatment 0.319 0.0373 0.39 0.267 0.0489 0.59 0.691 0.981 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J14 mock treatment 0.346 0.0643 0.68 0.258 0.0399 0.48 0.8154 0.9856 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J15 mock treatment 0.319 0.0373 0.39 0.26 0.0419 0.5 0.6318 0.9926 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J16 mock treatment 0.285 0.00333 0.03 0.258 0.0399 0.48 0.3624 0.7568 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J17 mock treatment 0.365 0.0833 0.88 0.255 0.0369 0.44 0.9311 0.9498 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J18 mock treatment 0.299 0.0173 0.18 0.236 0.0179 0.21 0.2802 0.9967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J19 mock treatment 0.302 0.0203 0.21 0.233 0.0149 0.18 0.2771 0.996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J20 mock treatment 0.352 0.0703 0.74 0.199 -0.0191 -0.23 0.3608 0.4667 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J21 mock treatment 0.295 0.0133 0.14 0.262 0.0439 0.53 0.4705 0.8653 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J22 mock treatment 0.325 0.0433 0.46 0.204 -0.0141 -0.17 0.2026 0.4175 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J23 mock treatment 0.287 0.00533 0.06 0.255 0.0369 0.44 0.3518 0.7903 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 J24 mock treatment 0.314 0.0323 0.34 0.233 0.0149 0.18 0.3662 0.9549 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K01 compound treatment 0.383 0.101 1.06 0.376 0.158 1.89 2.0884 0.9631 3125286 ChemDiv3_016609 O=C(Nc1ccccc1)N2CCC(=CC2)c3c[nH]c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K02 compound treatment 0.272 -0.00967 -0.1 0.24 0.0219 0.26 0.1135 0.4038 3044589 ChemDiv3_016610 O=C1CN(c2ccccc2N1)S(=O)(=O)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K03 compound treatment 0.385 0.103 1.09 0.227 0.00891 0.11 0.8427 0.7729 3125287 ChemDiv3_016611 CN(CC(=O)Nc1cccc(C)c1)S(=O)(=O)c2ccc(cc2)c3cc(C)no3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K04 mock treatment 0.24 -0.0417 -0.44 0.19 -0.0281 -0.34 -0.5471 -0.9915 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K05 compound treatment 0.45 0.168 1.77 0.35 0.132 1.58 2.3661 0.9984 3125288 ChemDiv3_016612 CC1CCC(CC1)NC(=O)c2cc(n[nH]2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K06 mock treatment 0.273 -0.00867 -0.09 0.241 0.0229 0.27 0.1294 0.448 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K07 compound treatment 0.287 0.00533 0.06 0.198 -0.0201 -0.24 -0.1304 -0.5284 3125289 ChemDiv3_016613 COc1ccc(CCNC(=O)CN2C=NS(=O)(=O)c3ccccc23)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K08 mock treatment 0.259 -0.0227 -0.24 0.186 -0.0321 -0.38 -0.4399 -0.9736 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K09 compound treatment 0.335 0.0533 0.56 0.237 0.0189 0.23 0.556 0.9205 3043570 ChemDiv3_016614 Cc1ccc(CNC(=O)CSC2=NS(=O)(=O)c3ccccc3N2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K10 mock treatment 0.238 -0.0437 -0.46 0.216 -0.00209 -0.02 -0.342 -0.7445 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K11 compound treatment 0.071 -0.211 -2.21 0.056 -0.162 -1.94 -2.9359 -0.9978 3043571 ChemDiv3_016615 COc1cccc2cc(CC(=O)O)oc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K12 mock treatment 0.225 -0.0567 -0.6 0.191 -0.0271 -0.32 -0.6501 -0.9592 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K13 compound treatment 0.312 0.0303 0.32 0.241 0.0229 0.27 0.419 0.9972 3043573 ChemDiv3_016616 CCC(C)NC(=O)C1N(Cc2ccccc2OC)C(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K14 mock treatment 0.26 -0.0217 -0.23 0.191 -0.0271 -0.32 -0.3901 -0.9851 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K15 compound treatment 0.339 0.0573 0.6 0.241 0.0229 0.27 0.6196 0.9366 3043575 ChemDiv3_016617 COc1ccc(CCNC(=O)C2N(C3CCCCCC3)C(=O)c4ccccc24)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K16 mock treatment 0.266 -0.0157 -0.16 0.214 -0.00409 -0.05 -0.151 -0.8792 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K17 compound treatment 0.272 -0.00967 -0.1 0.187 -0.0311 -0.37 -0.3349 -0.8685 3043576 ChemDiv3_016618 O=C(C1CN(C2CCCC2)C(=O)C1)N3CCC4(CC3)OCCO4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K18 mock treatment 0.304 0.0223 0.23 0.189 -0.0291 -0.35 -0.0803 -0.1913 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K19 compound treatment 0.314 0.0323 0.34 0.224 0.00591 0.07 0.2901 0.8365 3043578 ChemDiv3_016619 O=C(C1CCC(=O)N1C2CCCC2)N3CCN(CC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K20 mock treatment 0.302 0.0203 0.21 0.243 0.0249 0.3 0.3617 0.9866 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K21 compound treatment 0.242 -0.0397 -0.42 0.21 -0.00809 -0.1 -0.3631 -0.8487 3043580 ChemDiv3_016620 COc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(OC)nc3OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K22 mock treatment 0.282 3.25E-4 0.0 0.192 -0.0261 -0.31 -0.2183 -0.6993 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K23 mock treatment 0.231 -0.0507 -0.53 0.22 0.00191 0.02 -0.3602 -0.6761 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 K24 mock treatment 0.26 -0.0217 -0.23 0.232 0.0139 0.17 -0.0433 -0.1534 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L01 mock treatment 0.269 -0.0127 -0.13 0.2 -0.0181 -0.22 -0.2472 -0.9728 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L02 mock treatment 0.223 -0.0587 -0.62 0.185 -0.0331 -0.4 -0.7157 -0.9771 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L03 mock treatment 0.369 0.0873 0.92 0.25 0.0319 0.38 0.9185 0.9246 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L04 mock treatment 0.264 -0.0177 -0.19 0.206 -0.0121 -0.14 -0.2335 -0.9924 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L05 mock treatment 0.298 0.0163 0.17 0.275 0.0569 0.68 0.6027 0.8584 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L06 mock treatment 0.315 0.0333 0.35 0.269 0.0509 0.61 0.6782 0.9654 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L07 mock treatment 0.396 0.114 1.2 0.206 -0.0121 -0.14 0.7468 0.6175 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L08 mock treatment 0.356 0.0743 0.78 0.308 0.0899 1.08 1.3126 0.9876 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L09 mock treatment 0.293 0.0113 0.12 0.268 0.0499 0.6 0.5064 0.8316 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L10 mock treatment 0.307 0.0253 0.27 0.265 0.0469 0.56 0.585 0.9418 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L11 mock treatment 0.306 0.0243 0.26 0.262 0.0439 0.53 0.5522 0.9451 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L12 mock treatment 0.284 0.00233 0.02 0.255 0.0369 0.44 0.3295 0.7451 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L13 mock treatment 0.319 0.0373 0.39 0.253 0.0349 0.42 0.5726 0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L14 mock treatment 0.338 0.0563 0.59 0.219 9.12E-4 0.01 0.426 0.72 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L15 mock treatment 0.308 0.0263 0.28 0.257 0.0389 0.47 0.5247 0.969 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L16 mock treatment 0.288 0.00633 0.07 0.254 0.0359 0.43 0.3508 0.8068 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L17 mock treatment 0.267 -0.0147 -0.15 0.245 0.0269 0.32 0.1187 0.3325 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L18 mock treatment 0.302 0.0203 0.21 0.222 0.00391 0.05 0.184 0.8421 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L19 mock treatment 0.293 0.0113 0.12 0.231 0.0129 0.15 0.1933 0.9917 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L20 mock treatment 0.298 0.0163 0.17 0.218 -8.8E-5 0.0 0.1205 0.7027 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L21 mock treatment 0.353 0.0713 0.75 0.225 0.00691 0.08 0.5882 0.7804 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L22 mock treatment 0.32 0.0383 0.4 0.222 0.00391 0.05 0.3177 0.784 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L23 mock treatment 0.244 -0.0377 -0.4 0.226 0.00791 0.09 -0.2129 -0.5232 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 L24 mock treatment 0.23 -0.0517 -0.54 0.227 0.00891 0.11 -0.3084 -0.5575 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M01 compound treatment 0.113 -0.169 -1.77 0.105 -0.113 -1.35 -2.2094 -0.9911 3125290 ChemDiv3_016621 Cc1ccc(CNC(=O)N2CCC(=CC2)c3c[nH]c4ccccc34)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M02 compound treatment 0.296 0.0143 0.15 0.221 0.00291 0.03 0.131 0.8484 3125291 ChemDiv3_016622 CC(CC(=O)N1CCOCC1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M03 compound treatment 0.479 0.197 2.07 0.421 0.203 2.43 3.1821 0.9969 3043582 ChemDiv3_016623 COc1cccc(NS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M04 mock treatment 0.27 -0.0117 -0.12 0.186 -0.0321 -0.38 -0.3582 -0.8887 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M05 compound treatment 0.101 -0.181 -1.9 0.094 -0.124 -1.48 -2.3916 -0.9926 3125292 ChemDiv3_016624 Fc1ccccc1N2CCN(CCNC(=O)c3cc(n[nH]3)c4ccccc4)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M06 mock treatment 0.267 -0.0147 -0.15 0.195 -0.0231 -0.28 -0.3043 -0.962 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M07 compound treatment 0.552 0.27 2.84 0.427 0.209 2.5 3.775 0.998 3043584 ChemDiv3_016625 Cc1ccc(cc1)N2C(=O)N(CC(=O)C(C)(C)C)c3ccccc3S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M08 mock treatment 0.321 0.0393 0.41 0.232 0.0139 0.17 0.4097 0.9202 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M09 compound treatment 0.356 0.0743 0.78 0.284 0.0659 0.79 1.1096 1.0 3125293 ChemDiv3_016626 CCOC(=O)CN1C(=O)N(c2ccccc2OC)S(=O)(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M10 mock treatment 0.281 -6.75E-4 -0.01 0.208 -0.0101 -0.12 -0.0904 -0.7473 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M11 compound treatment 0.238 -0.0437 -0.46 0.188 -0.0301 -0.36 -0.5789 -0.9928 3043586 ChemDiv3_016627 Cc1ccc2OCC(=O)N(CCCC(=O)O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M12 mock treatment 0.272 -0.00967 -0.1 0.202 -0.0161 -0.19 -0.208 -0.9554 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M13 compound treatment 0.246 -0.0357 -0.37 0.214 -0.00409 -0.05 -0.2995 -0.7927 3125294 ChemDiv3_016628 Cc1ccc(CNC(=O)CNc2ccccc2c3nc4ccccc4[nH]c3=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M14 mock treatment 0.296 0.0143 0.15 0.225 0.00691 0.08 0.1649 0.9603 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M15 compound treatment 0.303 0.0213 0.22 0.223 0.00491 0.06 0.1999 0.8634 3125295 ChemDiv3_016629 COc1ccc(CCNC(=O)C2N(CCC(C)C)C(=O)c3ccccc23)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M16 mock treatment 0.274 -0.00767 -0.08 0.202 -0.0161 -0.19 -0.1931 -0.9254 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M17 compound treatment 0.399 0.117 1.23 0.298 0.0799 0.96 1.5474 0.9921 3043589 ChemDiv3_016630 Fc1ccc(cc1)N2CCN(CC2)C(=O)C3CN(C4CCCC4)C(=O)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M18 mock treatment 0.229 -0.0527 -0.55 0.202 -0.0161 -0.19 -0.5273 -0.9002 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M19 compound treatment 0.412 0.13 1.37 0.298 0.0799 0.96 1.6439 0.9846 3125296 ChemDiv3_016631 CC(N1CC(CC1=O)C(=O)N2CCN(CC2)c3ccc(F)cc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M20 mock treatment 0.25 -0.0317 -0.33 0.228 0.00991 0.12 -0.1514 -0.4286 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M21 compound treatment 0.153 -0.129 -1.35 0.174 -0.0441 -0.53 -1.3286 -0.9158 3043590 ChemDiv3_016632 Cc1cccc(n1)N2CCN(CC2)C(=O)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M22 mock treatment 0.321 0.0393 0.41 0.228 0.00991 0.12 0.3759 0.8748 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M23 mock treatment 0.215 -0.0667 -0.7 0.196 -0.0221 -0.26 -0.682 -0.9112 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 M24 mock treatment 0.281 -6.75E-4 -0.01 0.225 0.00691 0.08 0.0535 0.6441 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N01 mock treatment 0.293 0.0113 0.12 0.187 -0.0311 -0.37 -0.1789 -0.4581 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N02 mock treatment 0.298 0.0163 0.17 0.264 0.0459 0.55 0.5097 0.8857 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N03 mock treatment 0.217 -0.0647 -0.68 0.177 -0.0411 -0.49 -0.8279 -0.9874 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N04 mock treatment 0.297 0.0153 0.16 0.228 0.00991 0.12 0.1977 0.9887 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N05 mock treatment 0.299 0.0173 0.18 0.242 0.0239 0.29 0.331 0.9761 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N06 mock treatment 0.296 0.0143 0.15 0.248 0.0299 0.36 0.3594 0.9259 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N07 mock treatment 0.338 0.0563 0.59 0.22 0.00191 0.02 0.4345 0.7339 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N08 mock treatment 0.272 -0.00967 -0.1 0.215 -0.00309 -0.04 -0.098 -0.9062 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N09 mock treatment 0.318 0.0363 0.38 0.222 0.00391 0.05 0.3029 0.7879 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N10 mock treatment 0.259 -0.0227 -0.24 0.219 9.12E-4 0.01 -0.1607 -0.674 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N11 mock treatment 0.322 0.0403 0.42 0.268 0.0499 0.6 0.7217 0.9858 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N12 mock treatment 0.27 -0.0117 -0.12 0.23 0.0119 0.14 0.0141 0.0749 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N13 mock treatment 0.281 -6.75E-4 -0.01 0.233 0.0149 0.18 0.1211 0.6785 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N14 mock treatment 0.309 0.0273 0.29 0.253 0.0349 0.42 0.4983 0.9832 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N15 mock treatment 0.317 0.0353 0.37 0.225 0.00691 0.08 0.3208 0.844 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N16 mock treatment 0.283 0.00133 0.01 0.196 -0.0221 -0.26 -0.177 -0.6689 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N17 mock treatment 0.305 0.0233 0.24 0.25 0.0319 0.38 0.4432 0.977 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N18 mock treatment 0.282 3.25E-4 0.0 0.226 0.00791 0.09 0.0694 0.7321 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N19 mock treatment 0.307 0.0253 0.27 0.249 0.0309 0.37 0.4496 0.9869 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N20 mock treatment 0.305 0.0233 0.24 0.208 -0.0101 -0.12 0.0879 0.3218 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N21 mock treatment 0.291 0.00933 0.1 0.218 -8.8E-5 0.0 0.0685 0.6995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N22 mock treatment 0.257 -0.0247 -0.26 0.215 -0.00309 -0.04 -0.2094 -0.7998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N23 mock treatment 0.265 -0.0167 -0.18 0.202 -0.0161 -0.19 -0.2599 -0.9989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 N24 mock treatment 0.255 -0.0267 -0.28 0.224 0.00591 0.07 -0.1481 -0.5125 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O01 compound treatment 0.164 -0.118 -1.24 0.168 -0.0501 -0.6 -1.2977 -0.9448 3125297 ChemDiv3_016633 Cc1oc(nc1COc2ccc(C)cc2)c3ccc(cc3)C(=O)NC4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O02 compound treatment 0.292 0.0103 0.11 0.221 0.00291 0.03 0.1013 0.8895 3043592 ChemDiv3_016634 COC(=O)Cn1cc(cc1C(=O)OC)S(=O)(=O)N2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O03 compound treatment 0.307 0.0253 0.27 0.27 0.0519 0.62 0.6273 0.9284 3125298 ChemDiv3_016635 O=C1N(Cc2ccc(s2)S(=O)(=O)NCCc3ccccc3)C(=O)c4ncccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O04 mock treatment 0.209 -0.0727 -0.76 0.203 -0.0151 -0.18 -0.6674 -0.8509 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O05 compound treatment 0.202 -0.0797 -0.84 0.184 -0.0341 -0.41 -0.8801 -0.9454 3125299 ChemDiv3_016636 COc1ccc(NC(=O)CCS(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O06 mock treatment 0.254 -0.0277 -0.29 0.207 -0.0111 -0.13 -0.2993 -0.9369 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O07 compound treatment 0.207 -0.0747 -0.78 0.184 -0.0341 -0.41 -0.843 -0.9536 3043644 ChemDiv3_016637 CN1C(=O)N(c2ccc(C)cc2)S(=O)(=O)c3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O08 mock treatment 0.265 -0.0167 -0.18 0.187 -0.0311 -0.37 -0.3868 -0.941 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O09 compound treatment 0.246 -0.0357 -0.37 0.2 -0.0181 -0.22 -0.418 -0.966 3125300 ChemDiv3_016638 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)NCc4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O10 mock treatment 0.254 -0.0277 -0.29 0.197 -0.0211 -0.25 -0.3839 -0.9975 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O11 compound treatment 0.298 0.0163 0.17 0.253 0.0349 0.42 0.4166 0.9227 3043646 ChemDiv3_016639 CCOC(=O)CN1C(=O)/C(=C/c2ccc(Cl)cc2)/Oc3ccc(cc13)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O12 mock treatment 0.227 -0.0547 -0.57 0.191 -0.0271 -0.32 -0.6352 -0.9634 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O13 compound treatment 0.268 -0.0137 -0.14 0.209 -0.00909 -0.11 -0.1784 -0.9906 3125301 ChemDiv3_016640 CC(C)N1C(CCC1=O)C(=O)N2CCN(C(C)C2)c3cccc(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O14 mock treatment 0.196 -0.0857 -0.9 0.224 0.00591 0.07 -0.5862 -0.6495 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O15 compound treatment 0.287 0.00533 0.06 0.218 -8.8E-5 0.0 0.0388 0.6937 3125302 ChemDiv3_016641 CC1(CCC(=O)N1CCC2=CCCCC2)C(=O)NC3CCCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O16 mock treatment 0.286 0.00433 0.05 0.216 -0.00209 -0.02 0.0145 0.2788 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O17 compound treatment 0.488 0.206 2.17 0.417 0.199 2.38 3.2151 0.9989 3043648 ChemDiv3_016642 O=C(NCc1ccccn1)C2CCC(=O)N2C3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O18 mock treatment 0.276 -0.00567 -0.06 0.202 -0.0161 -0.19 -0.1783 -0.8846 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O19 compound treatment 0.209 -0.0727 -0.76 0.174 -0.0441 -0.53 -0.9127 -0.9837 3125303 ChemDiv3_016643 COC(CNC(=O)C1CCC(=O)N1Cc2ccc(F)cc2)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O20 mock treatment 0.229 -0.0527 -0.55 0.196 -0.0221 -0.26 -0.5781 -0.9428 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O21 compound treatment 0.314 0.0323 0.34 0.235 0.0169 0.2 0.3831 0.9694 3043650 ChemDiv3_016644 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)NCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O22 mock treatment 0.245 -0.0367 -0.39 0.172 -0.0461 -0.55 -0.6623 -0.9846 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O23 mock treatment 0.242 -0.0397 -0.42 0.178 -0.0401 -0.48 -0.6338 -0.9975 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 O24 mock treatment 0.252 -0.0297 -0.31 0.246 0.0279 0.33 0.0158 0.0345 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P01 mock treatment 0.305 0.0233 0.24 0.203 -0.0151 -0.18 0.0456 0.1498 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P02 mock treatment 0.305 0.0233 0.24 0.253 0.0349 0.42 0.4686 0.9677 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P03 mock treatment 0.251 -0.0307 -0.32 0.19 -0.0281 -0.34 -0.4654 -0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P04 mock treatment 0.241 -0.0407 -0.43 0.187 -0.0311 -0.37 -0.5651 -0.9976 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P05 mock treatment 0.24 -0.0417 -0.44 0.212 -0.00609 -0.07 -0.361 -0.8136 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P06 mock treatment 0.279 -0.00267 -0.03 0.259 0.0409 0.49 0.3263 0.6654 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P07 mock treatment 0.309 0.0273 0.29 0.226 0.00791 0.09 0.2699 0.893 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P08 mock treatment 0.241 -0.0407 -0.43 0.178 -0.0401 -0.48 -0.6412 -0.9983 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P09 mock treatment 0.252 -0.0297 -0.31 0.221 0.00291 0.03 -0.1957 -0.6242 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P10 mock treatment 0.25 -0.0317 -0.33 0.171 -0.0471 -0.56 -0.6336 -0.9684 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P11 mock treatment 0.212 -0.0697 -0.73 0.241 0.0229 0.27 -0.3236 -0.4141 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P12 mock treatment 0.249 -0.0327 -0.34 0.18 -0.0381 -0.46 -0.5649 -0.9902 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P13 mock treatment 0.239 -0.0427 -0.45 0.193 -0.0251 -0.3 -0.5292 -0.981 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P14 mock treatment 0.198 -0.0837 -0.88 0.18 -0.0381 -0.46 -0.9436 -0.9532 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P15 mock treatment 0.259 -0.0227 -0.24 0.189 -0.0291 -0.35 -0.4145 -0.9829 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P16 mock treatment 0.237 -0.0447 -0.47 0.189 -0.0291 -0.35 -0.5779 -0.9892 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P17 mock treatment 0.227 -0.0547 -0.57 0.22 0.00191 0.02 -0.3899 -0.6784 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P18 mock treatment 0.222 -0.0597 -0.63 0.202 -0.0161 -0.19 -0.5793 -0.8835 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P19 mock treatment 0.237 -0.0447 -0.47 0.2 -0.0181 -0.22 -0.4848 -0.9383 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P20 mock treatment 0.229 -0.0527 -0.55 0.225 0.00691 0.08 -0.3327 -0.5948 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P21 mock treatment 0.231 -0.0507 -0.53 0.253 0.0349 0.42 -0.081 -0.1197 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P22 mock treatment 0.227 -0.0547 -0.57 0.22 0.00191 0.02 -0.3899 -0.6784 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P23 mock treatment 0.266 -0.0157 -0.16 0.197 -0.0211 -0.25 -0.2948 -0.9786 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2048 P24 mock treatment 0.192 -0.0897 -0.94 0.214 -0.00409 -0.05 -0.7006 -0.7428 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A01 compound treatment 0.143 -0.049 -0.51 0.171 -0.0181 -0.22 -0.5169 -0.9256 1042961 Maybridge4_000001 Clc1ccc(cc1)N2CCNCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A02 compound treatment 0.183 -0.00903 -0.09 0.22 0.0309 0.37 0.1947 0.5094 3062731 Maybridge4_000002 CC(=O)NS(=O)(=O)c1ccc(/N=C/c2ccco2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A03 compound treatment 0.155 -0.037 -0.39 0.153 -0.0361 -0.43 -0.5801 -0.9987 3062732 Maybridge4_000003 FC(F)(F)Oc1ccc(NC(=O)Nc2ccc(cc2)C3=NCCO3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A04 compound treatment 0.673 0.481 5.05 0.643 0.454 5.43 7.4123 0.9993 1175682 Maybridge4_000004 COc1cccc2cc(C#N)c(=N)oc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A05 compound treatment 0.061 -0.131 -1.38 0.06 -0.129 -1.54 -2.065 -0.9983 3062733 Maybridge4_000005 Cc1nc(ccc1C(=O)Sc2nnc(o2)c3ccc(nc3C)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A06 compound treatment 0.871 0.679 7.13 0.866 0.677 8.1 10.7694 0.998 3062734 Maybridge4_000006 COc1cc(/N=C/c2cccs2)c(OC)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A07 compound treatment 0.148 -0.044 -0.46 0.155 -0.0341 -0.41 -0.6152 -0.998 3062735 Maybridge4_000007 OC1CCN(CC1)C(=O)Nc2ccc(OC(F)(F)F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A08 compound treatment 0.273 0.081 0.85 0.362 0.173 2.07 2.0644 0.9228 1676427 Maybridge4_000008 Cc1ccccc1NC(=S)Nc2cc(NS(=O)(=O)C)ccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A09 compound treatment 0.211 0.019 0.2 0.189 -6.25E-5 0.0 0.1403 0.7044 3179439 Maybridge4_000009 Cc1nc(ccc1NC(=O)NCCNc2cccc(n2)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A10 compound treatment 0.148 -0.044 -0.46 0.186 -0.00306 -0.04 -0.3529 -0.7607 3062736 Maybridge4_000010 Cc1ccc(NC(=S)Nc2cccc(c2)C(F)(F)F)cc1NS(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A11 compound treatment 0.169 -0.023 -0.24 0.165 -0.0241 -0.29 -0.3746 -0.9963 3179440 Maybridge4_000011 CC(C)(C)NC(=O)N1CCC(CC1)Nc2nccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A12 compound treatment 0.169 -0.023 -0.24 0.187 -0.00206 -0.02 -0.1885 -0.7752 3062737 Maybridge4_000012 Fc1cccc(/N=C/c2ccc3OCOc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A13 compound treatment 0.148 -0.044 -0.46 0.154 -0.0351 -0.42 -0.6236 -0.9988 3179441 Maybridge4_000013 OC(=O)c1ccccc1C(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A14 compound treatment 0.168 -0.024 -0.25 0.185 -0.00406 -0.05 -0.2128 -0.8281 3062738 Maybridge4_000014 CCOC(=O)CCN1C(=O)c2ccccc2C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A15 compound treatment 1.216 1.02 10.75 1.177 0.988 11.82 15.9626 0.9989 1678888 Maybridge4_000015 C(Cc1ccccc1)Nc2ncnc3scc(c4ccccc4)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A16 compound treatment 0.121 -0.071 -0.75 0.135 -0.0541 -0.65 -0.9849 -0.9975 1222400 Maybridge4_000016 Oc1ccc(CCc2nnc(S)n2CCc3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A17 compound treatment 0.169 -0.023 -0.24 0.157 -0.0321 -0.38 -0.4423 -0.9753 3179442 Maybridge4_000017 OC(=O)/C=C/C(=O)N1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A18 compound treatment 0.317 0.125 1.31 0.27 0.0809 0.97 1.6128 0.9888 3179443 Maybridge4_000018 CN(C(=O)CSc1ccc(Cl)cc1)c2ccccc2C(=O)NC3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A19 compound treatment 0.582 0.39 4.1 0.557 0.368 4.4 6.0089 0.9994 1712315 Maybridge4_000019 COc1cccc(OC)c1C(=O)N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A20 compound treatment 0.39 0.198 2.08 0.35 0.161 1.93 2.8318 0.9993 3179444 Maybridge4_000020 CC(C)(C)NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A21 compound treatment 0.166 -0.026 -0.27 0.162 -0.0271 -0.32 -0.4223 -0.9965 3062739 Maybridge4_000021 NC(=O)C1CCN(CC1)c2nccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A22 compound treatment 0.339 0.147 1.54 0.326 0.137 1.64 2.25 0.9996 1149418 Maybridge4_000022 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Oc2c(C)cccc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A23 mock treatment 0.184 -0.00803 -0.08 0.17 -0.0191 -0.23 -0.2209 -0.9085 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 A24 mock treatment 0.226 0.034 0.36 0.207 0.0179 0.21 0.404 0.9704 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B01 compound treatment 0.092 -0.1 -1.05 0.099 -0.0901 -1.08 -1.5048 -0.9999 3062740 Maybridge4_000023 CCSC1=NCN(Cc2cccs2)CN1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B02 compound treatment 0.261 0.069 0.72 0.261 0.0719 0.86 1.1208 0.9963 3179445 Maybridge4_000024 Cc1ccc(CNC(=O)c2cccnc2Sc3cccc(c3)C(F)(F)F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B03 compound treatment 0.042 -0.15 -1.58 0.044 -0.145 -1.74 -2.3415 -0.9988 3062741 Maybridge4_000025 CN(/N=C/c1cc(Cl)cc(Cl)c1O)C(=S)NC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B04 compound treatment 0.139 -0.053 -0.56 0.113 -0.0761 -0.91 -1.0373 -0.9722 3179446 Maybridge4_000026 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)/C=C\C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B05 compound treatment 0.14 -0.052 -0.55 0.176 -0.0131 -0.16 -0.4969 -0.8743 3062742 Maybridge4_000027 Cc1c(C)c(C)c(CS(=O)(=O)CC(=O)Nc2ccc(F)c(Cl)c2)c(C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B06 compound treatment 0.16 -0.032 -0.34 0.188 -0.00106 -0.01 -0.2469 -0.7333 1435448 Maybridge4_000028 Cc1onc(c1NC(=O)Oc2ccc(CC#N)cc2)c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B07 compound treatment 0.117 -0.075 -0.79 0.127 -0.0621 -0.74 -1.0823 -0.9996 1192420 Maybridge4_000029 S=C(NCCc1ccccn1)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B08 compound treatment 0.287 0.095 1.0 0.284 0.0949 1.14 1.5085 0.9979 1239033 Maybridge4_000030 CSc1nnc(SC)n1CCNC(=O)Nc2cccc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B09 compound treatment 0.134 -0.058 -0.61 0.14 -0.0491 -0.59 -0.846 -0.9998 3179447 Maybridge4_000031 Fc1c(Br)cc(Br)c2nc(oc(=O)c12)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B10 compound treatment 0.209 0.017 0.18 0.204 0.0149 0.18 0.2524 1.0 3062743 Maybridge4_000032 Fc1ccc(Oc2ccc(NC(=O)/C=C/c3ccccc3)cn2)c(F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B11 compound treatment 0.042 -0.15 -1.58 0.042 -0.147 -1.76 -2.3584 -0.9985 3179448 Maybridge4_000033 FC(F)(F)c1ccc2[nH]c(SCc3ccc(Br)cc3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B12 compound treatment 0.175 -0.017 -0.18 0.184 -0.00506 -0.06 -0.1693 -0.8965 1161087 Maybridge4_000034 Fc1ccc(cc1)n2nc3NCCCn3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B13 compound treatment 0.044 -0.148 -1.55 0.049 -0.14 -1.68 -2.2843 -0.9993 3062744 Maybridge4_000035 FC(F)(F)c1cccc(c1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B14 compound treatment 0.563 0.371 3.9 0.467 0.278 3.33 5.1064 0.9969 1279124 Maybridge4_000036 CCCCn1c(CSc2ccccn2)cn(c3nnc(s3)C(C)(C)C)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B15 compound treatment 0.123 -0.069 -0.73 0.161 -0.0281 -0.34 -0.7501 -0.9388 1108923 Maybridge4_000037 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B16 compound treatment 0.395 0.203 2.13 0.377 0.188 2.25 3.0973 0.9996 1163777 Maybridge4_000038 CC(C)(C)c1cc(cc(c1)C(=O)Oc2cncc(Cl)c2)C(=O)Oc3cncc(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B17 compound treatment 0.186 -0.00603 -0.06 0.205 0.0159 0.19 0.09 0.4481 1150645 Maybridge4_000039 Cc1cc(NS(=O)(=O)c2ccc(F)c(Cl)c2)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B18 compound treatment 0.451 0.259 2.72 0.422 0.233 2.79 3.8939 0.9999 3179449 Maybridge4_000040 CSc1ncccc1C2=N/C(=C\N(C)C)/C(=O)O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B19 compound treatment 0.218 0.026 0.27 0.239 0.0499 0.6 0.6153 0.9369 3062745 Maybridge4_000041 CN(C)/C=N/c1nnc(SCC(=O)c2ccc(F)cc2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B20 compound treatment 0.191 -0.00103 -0.01 0.215 0.0259 0.31 0.2118 0.682 3179558 Maybridge4_000042 COC(=O)/C(=C/1\NC(=NC(=C1C#N)SC)C)/C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B21 compound treatment 0.072 -0.12 -1.26 0.076 -0.113 -1.35 -1.8479 -0.9994 3179559 Maybridge4_000043 CN(C)/C=N/c1nnc(Sc2cc(C)nc3ccccc23)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B22 compound treatment 1.097 0.905 9.5 1.141 0.952 11.39 14.7743 0.996 3062746 Maybridge4_000044 CCOC(=O)c1c(C)c(C#N)c(/N=C/N(C)C)n1c2ccc(Cl)cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B23 mock treatment 0.172 -0.02 -0.21 0.167 -0.0221 -0.26 -0.3354 -0.9937 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 B24 mock treatment 0.174 -0.018 -0.19 0.174 -0.0151 -0.18 -0.2613 -0.9997 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C01 compound treatment 0.127 -0.065 -0.68 0.161 -0.0281 -0.34 -0.7204 -0.9465 1040601 Maybridge4_000045 COc1cccc(c1)N2CCNCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C02 compound treatment 0.202 0.00997 0.1 0.21 0.0209 0.25 0.2512 0.9251 3062747 Maybridge4_000046 COc1cc(/C=N/N)cc(OC)c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C03 compound treatment 0.13 -0.062 -0.65 0.132 -0.0571 -0.68 -0.9434 -0.9997 3179560 Maybridge4_000047 FC(F)(F)c1cccnc1N2CCNC2=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C04 compound treatment 1.38 1.19 12.48 1.367 1.18 14.09 18.788 0.9982 1723231 Maybridge4_000048 Clc1c(sc2ccccc12)C(=O)N(Cc3ccccc3)C(C#N)c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C05 compound treatment 0.168 -0.024 -0.25 0.184 -0.00506 -0.06 -0.2213 -0.8526 3062748 Maybridge4_000049 Cc1ccc(NC(=S)N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C06 compound treatment 0.19 -0.00203 -0.02 0.229 0.0399 0.48 0.3228 0.6749 1322626 Maybridge4_000050 Fc1ccc(cc1)N(Cc2ccc3OCOc3c2)S(=O)(=O)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C07 compound treatment 0.257 0.065 0.68 0.241 0.0519 0.62 0.9219 0.9989 1288233 Maybridge4_000051 CCOC(=O)c1cc(C(=O)OC)c(C)nc1N2CCCN(Cc3ccc(F)cc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C08 compound treatment 0.217 0.025 0.26 0.27 0.0809 0.97 0.8702 0.8674 3179561 Maybridge4_000052 CCOC(=O)/C(=C(/C)\N)/C1CC(=O)N(C1=O)c2ccc(cc2)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C09 compound treatment 0.263 0.071 0.75 0.261 0.0719 0.86 1.1357 0.9974 1354107 Maybridge4_000053 OC(COc1ccc(Br)cc1)CN2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C10 compound treatment 0.203 0.011 0.12 0.215 0.0259 0.31 0.3009 0.909 1692586 Maybridge4_000054 Cc1ccc(cc1)S(=O)(=O)N(c2nc3ccccc3s2)c4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C11 compound treatment 0.183 -0.00903 -0.09 0.236 0.0469 0.56 0.33 0.5795 1369581 Maybridge4_000055 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)Nc2ccc(F)cc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C12 compound treatment 0.431 0.239 2.51 0.43 0.241 2.88 3.8131 0.9976 1212228 Maybridge4_000056 Cc1ccc(c(NC(=O)C(C2CCCC2)c3ccccc3)c1)n4cccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C13 compound treatment 0.185 -0.00703 -0.07 0.179 -0.0101 -0.12 -0.1373 -0.9725 3179562 Maybridge4_000057 Cc1nc(ccc1C(=O)NCC2CC2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C14 compound treatment 0.253 0.061 0.64 0.232 0.0429 0.51 0.816 0.994 1629863 Maybridge4_000058 Oc1c(Cl)cc(Cl)cc1C2Nc3cccc4cccc(N2)c34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C15 compound treatment 0.139 -0.053 -0.56 0.148 -0.0411 -0.49 -0.7412 -0.998 3062749 Maybridge4_000059 CCCNC(=O)NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C16 compound treatment 0.247 0.055 0.58 0.202 0.0129 0.15 0.5177 0.8661 1569566 Maybridge4_000060 CC(c1ccccc1)n2c(S)nnc2CCc3ccc(O)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C17 compound treatment 0.115 -0.077 -0.81 0.125 -0.0641 -0.77 -1.1141 -0.9996 1204274 Maybridge4_000061 Fc1cccc(Cl)c1CN2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C18 compound treatment 0.238 0.046 0.48 0.188 -0.00106 -0.01 0.3324 0.6882 1455358 Maybridge4_000062 O=C(Nc1nccc2ccccc12)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C19 compound treatment 0.208 0.016 0.17 0.19 9.38E-4 0.01 0.1265 0.7527 3179563 Maybridge4_000063 COc1cccc(CC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C20 compound treatment 0.21 0.018 0.19 0.204 0.0149 0.18 0.2598 0.9996 3062750 Maybridge4_000064 CC(C)(C)NC(=S)Nc1ccccc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C21 compound treatment 0.272 0.08 0.84 0.244 0.0549 0.66 1.0587 0.9926 1137780 Maybridge4_000065 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2ccc(Oc3cccnc3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C22 compound treatment 0.107 -0.085 -0.89 0.117 -0.0721 -0.86 -1.2411 -0.9998 3179564 Maybridge4_000066 FC(F)(F)c1cc(NCC(=O)c2cc3cc(Cl)ccc3o2)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C23 mock treatment 0.171 -0.021 -0.22 0.164 -0.0251 -0.3 -0.3682 -0.9887 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 C24 mock treatment 0.22 0.028 0.29 0.194 0.00494 0.06 0.2495 0.8326 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D01 compound treatment 0.318 0.126 1.32 0.32 0.131 1.57 2.0433 0.9965 3179565 Maybridge4_000067 Cc1nn(nc1C(=O)Oc2c(Cl)cccc2Cl)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D02 compound treatment 0.113 -0.079 -0.83 0.116 -0.0731 -0.87 -1.205 -0.9997 3062751 Maybridge4_000068 COc1cc(cc(Br)c1OC(=O)NC(=O)c2c(F)cccc2F)C3SCCS3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D03 compound treatment 0.861 0.669 7.03 0.763 0.574 6.87 9.8237 0.9999 1545199 Maybridge4_000069 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1N3CC(C)OC(C)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D04 compound treatment 0.052 -0.14 -1.47 0.052 -0.137 -1.64 -2.1995 -0.9985 1652603 Maybridge4_000070 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)CCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D05 compound treatment 0.189 -0.00303 -0.03 0.255 0.0659 0.79 0.5353 0.678 1338281 Maybridge4_000071 Clc1ccccc1C(=O)NC(=O)NC2CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D06 compound treatment 0.159 -0.033 -0.35 0.177 -0.0121 -0.14 -0.3474 -0.9245 1457562 Maybridge4_000072 OC(=O)C(CCC(=O)Nc1ccc2OCOCc2c1)N3C(=O)c4ccccc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D07 compound treatment 0.197 0.00497 0.05 0.21 0.0209 0.25 0.214 0.8365 3062752 Maybridge4_000073 CC1CN(CC(C)O1)C2=NCCN2S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D08 compound treatment 0.299 0.107 1.12 0.302 0.113 1.35 1.7499 0.9958 3179566 Maybridge4_000074 Cc1nn(nc1C(=O)c2c(O)n(nc2C(C)(C)C)c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D09 compound treatment 0.444 0.252 2.65 0.444 0.255 3.05 4.0281 0.9975 3062753 Maybridge4_000075 Cc1cc(Br)c(c(Br)c1Cl)n2cccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D10 compound treatment 0.281 0.089 0.93 0.357 0.168 2.01 2.0815 0.9393 3179567 Maybridge4_000076 Fc1ccc(Oc2ncccc2NC(=O)/C=C/c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D11 compound treatment 0.161 -0.031 -0.33 0.187 -0.00206 -0.02 -0.2479 -0.7585 3062754 Maybridge4_000077 CC(C)(C)c1cs/c(=N/c2ccccn2)/n1c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D12 compound treatment 0.552 0.36 3.78 0.54 0.351 4.2 5.6423 0.9986 1415138 Maybridge4_000078 CN1C(C(=O)N(C1=O)c2nnc(s2)C(C)(C)C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D13 compound treatment 0.313 0.121 1.27 0.267 0.0779 0.93 1.5577 0.9884 3063175 Maybridge4_000079 CC(C)(C)c1csc(Cc2ccccc2Cl)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D14 compound treatment 0.15 -0.042 -0.44 0.141 -0.0481 -0.58 -0.7188 -0.9915 3179568 Maybridge4_000080 Fc1ccc(NC(=O)CSc2nnc(NC(=O)c3ccc(Cl)c(Cl)c3)s2)c(F)c1F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D15 compound treatment 0.194 0.00197 0.02 0.207 0.0179 0.21 0.1664 0.7717 1691601 Maybridge4_000081 CS(=O)(=O)Nc1ccc2oc3ncccc3c(=O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D16 compound treatment 0.381 0.189 1.98 0.373 0.184 2.2 2.9595 0.9987 1489888 Maybridge4_000082 CC(C)(C)c1cc(cc(c1)C(=O)NCc2cccs2)C(=O)NCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D17 compound treatment 0.36 0.168 1.76 0.314 0.125 1.49 2.3044 0.9966 3063176 Maybridge4_000083 Clc1ccc(cc1Cl)C(=O)c2nn3c(nc(=O)c4ccccc43)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D18 compound treatment 0.678 0.486 5.1 0.658 0.469 5.61 7.5763 0.9989 3179569 Maybridge4_000084 CN(C)/C=C/1\N=C(OC1=O)c2cccnc2Oc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D19 compound treatment 0.182 -0.01 -0.11 0.199 0.00994 0.12 0.0096 0.0603 1342823 Maybridge4_000085 Fc1ccc(c(F)c1)S(=O)(=O)Nc2ccccc2C(=O)NCC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D20 compound treatment 0.25 0.058 0.61 0.283 0.0939 1.12 1.2252 0.9585 3063177 Maybridge4_000086 CC(C)(C(=O)Nc1cccc(Cl)c1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D21 compound treatment 0.92 0.728 7.65 0.81 0.621 7.43 10.6595 0.9999 3063178 Maybridge4_000087 CC1=NN(C(=O)CC1)c2cc(Cl)cc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D22 compound treatment 0.11 -0.082 -0.86 0.092 -0.0971 -1.16 -1.4304 -0.9892 1609394 Maybridge4_000088 CCOC(=O)c1c(C)c(C#N)c(N(C(=O)C)C(=O)C)n1c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D23 mock treatment 0.17 -0.022 -0.23 0.168 -0.0211 -0.25 -0.3418 -0.9991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 D24 mock treatment 0.173 -0.019 -0.2 0.181 -0.00806 -0.1 -0.2095 -0.9442 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E01 compound treatment 0.156 -0.036 -0.38 0.168 -0.0211 -0.25 -0.4458 -0.9805 1042964 Maybridge4_000089 Cc1cccc(c1)N2CCNCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E02 compound treatment 0.207 0.015 0.16 0.263 0.0739 0.88 0.7367 0.8199 1679137 Maybridge4_000090 NNC(=O)C1CCCNC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E03 compound treatment 0.271 0.079 0.83 0.279 0.0899 1.08 1.3473 0.9917 1296373 Maybridge4_000091 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2cc(Cl)ccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E04 compound treatment 0.157 -0.035 -0.37 0.15 -0.0391 -0.47 -0.5906 -0.993 1584716 Maybridge4_000092 COc1cc(cc(OC)c1OC)C(=O)NC(=S)NC(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E05 compound treatment 0.629 0.437 4.59 0.672 0.483 5.78 7.3309 0.9935 3063179 Maybridge4_000093 CSc1nnc(o1)c2ccc(nc2C)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E06 compound treatment 0.051 -0.141 -1.48 0.051 -0.138 -1.65 -2.2154 -0.9985 3179570 Maybridge4_000094 Cc1onc(c1C(=O)NC(=S)Nc2ccc(Cl)cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E07 compound treatment 1.358 1.17 12.25 1.379 1.19 14.24 18.7261 0.9972 1200576 Maybridge4_000095 CCOC(=O)c1cc(C(=O)OC)c(C)nc1SCC(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E08 compound treatment 0.259 0.067 0.7 0.24 0.0509 0.61 0.9283 0.9975 1402318 Maybridge4_000096 CCOC(=O)C1=C(C)NC(=O)C1CC(=O)Nc2ccc(cc2)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E09 compound treatment 1.09 0.898 9.43 1.073 0.884 10.58 14.147 0.9984 1736057 Maybridge4_000097 CCOC(=O)c1cc(C#N)c(C)nc1N2CCN(CC2)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E10 compound treatment 0.087 -0.105 -1.1 0.097 -0.0921 -1.1 -1.5589 -1.0 1619754 Maybridge4_000098 CC(=O)Nc1ccc(C)c(NC(=S)Nc2ccc(Cl)c(Cl)c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E11 compound treatment 0.504 0.312 3.28 0.483 0.294 3.52 4.8036 0.9994 1175297 Maybridge4_000099 O=C1CC2(CCCC2)C(=O)N1CCc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E12 compound treatment 0.256 0.064 0.67 0.274 0.0849 1.02 1.1936 0.9798 3179665 Maybridge4_000100 COc1cc(NC(=O)C(C2CCCC2)c3ccccc3)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E13 compound treatment 0.44 0.248 2.6 0.405 0.216 2.58 3.6684 1.0 1528875 Maybridge4_000101 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(s3)c4csc(C)n4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E14 compound treatment 0.185 -0.00703 -0.07 0.186 -0.00306 -0.04 -0.0781 -0.9477 1511104 Maybridge4_000102 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)CCC4CCCCN24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E15 compound treatment 0.155 -0.037 -0.39 0.202 0.0129 0.15 -0.1656 -0.3955 3063180 Maybridge4_000103 FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E16 compound treatment 0.36 0.168 1.76 0.334 0.145 1.73 2.4736 1.0 3179666 Maybridge4_000104 C/C(=N\C(=O)NN)/c1cnn(c1C)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E17 compound treatment 0.116 -0.076 -0.8 0.121 -0.0681 -0.81 -1.1405 -1.0 3179667 Maybridge4_000105 C(CNc1ncnc2scc(c3ccccc3)c12)Cn4ccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E18 compound treatment 0.102 -0.09 -0.95 0.102 -0.0871 -1.04 -1.4052 -0.9988 1369305 Maybridge4_000106 CCN1CCCC1CN2CNC(=S)NC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E19 compound treatment 0.112 -0.08 -0.84 0.112 -0.0771 -0.92 -1.2463 -0.9989 3179668 Maybridge4_000107 FC(F)(F)c1ccnc(n1)N2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E20 compound treatment 0.514 0.322 3.38 0.508 0.319 3.82 5.0894 0.9982 3063181 Maybridge4_000108 CSc1cccc(NC(=S)NC(C)(C)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E21 compound treatment 0.282 0.09 0.94 0.254 0.0649 0.78 1.2175 0.9953 1338166 Maybridge4_000109 Cc1cnc(N2CCN(CC2)NC(=S)Nc3cccnc3)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E22 compound treatment 0.042 -0.15 -1.58 0.043 -0.146 -1.75 -2.3499 -0.9987 1138152 Maybridge4_000110 COc1ccc(NC(=S)NC(C)(C)C)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E23 mock treatment 0.148 -0.044 -0.46 0.14 -0.0491 -0.59 -0.7421 -0.993 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 E24 mock treatment 0.176 -0.016 -0.17 0.178 -0.0111 -0.13 -0.2126 -0.9929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F01 compound treatment 0.18 -0.012 -0.13 0.205 0.0159 0.19 0.0455 0.1988 1442676 Maybridge4_000111 Fc1cccc(Cl)c1C(=O)NC(=O)N2CCSC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F02 compound treatment 0.326 0.134 1.41 0.323 0.134 1.6 2.128 0.9979 3179669 Maybridge4_000112 CN(C)/C(=N/c1nnc(Sc2nc3cc(Cl)ccc3s2)s1)/C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F03 compound treatment 0.292 0.1 1.05 0.295 0.106 1.27 1.6387 0.9956 3179670 Maybridge4_000113 Fc1ccc(NC(=O)NCSCc2cccc(c2)C(F)(F)F)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F04 compound treatment 0.314 0.122 1.28 0.344 0.155 1.85 2.2166 0.9837 1189445 Maybridge4_000114 COc1cccc(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F05 compound treatment 0.156 -0.036 -0.38 0.152 -0.0371 -0.44 -0.5811 -0.9969 3179671 Maybridge4_000115 FC(F)(F)c1cccc(c1)C(=O)NC2CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F06 compound treatment 0.12 -0.072 -0.76 0.154 -0.0351 -0.42 -0.8316 -0.9613 1529642 Maybridge4_000116 Cc1cc2ncc(nc2cc1C)c3ccn(c3)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F07 compound treatment 0.153 -0.039 -0.41 0.164 -0.0251 -0.3 -0.5019 -0.9882 1440337 Maybridge4_000117 Clc1cccc(Cl)c1C(=O)NC2CCS(=O)(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F08 compound treatment 0.39 0.198 2.08 0.351 0.162 1.94 2.8402 0.9994 1688196 Maybridge4_000118 COc1ccc(Cl)c(OC)c1C(=O)NC(=O)Nc2c(C)cccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F09 compound treatment 0.211 0.019 0.2 0.193 0.00394 0.05 0.1742 0.8509 3063182 Maybridge4_000119 COC(=O)/C=C/1\S/C(=N\c2ccc(C)c(C)c2)/N(C1=O)c3ccc(C)c(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F10 compound treatment 0.175 -0.017 -0.18 0.169 -0.0201 -0.24 -0.2962 -0.9895 3179672 Maybridge4_000120 NNC(=O)CS(=O)(=O)c1ccc(cn1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F11 compound treatment 0.187 -0.00503 -0.05 0.185 -0.00406 -0.05 -0.0717 -0.9991 3179673 Maybridge4_000121 Cc1ncc(CSc2nc3cc(ccc3[nH]2)C(F)(F)F)c(CO)c1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F12 compound treatment 0.23 0.038 0.4 0.215 0.0259 0.31 0.5014 0.9923 1621608 Maybridge4_000122 Cc1cc(cc(C)c1O)c2nn(C)c(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F13 compound treatment 0.388 0.196 2.06 0.392 0.203 2.43 3.1722 0.9966 1331054 Maybridge4_000123 CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)c2c(F)cccc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F14 compound treatment 0.152 -0.04 -0.42 0.174 -0.0151 -0.18 -0.4247 -0.9285 3063183 Maybridge4_000124 FC(F)(F)c1nnc(NC(=O)Nc2ccccc2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F15 compound treatment 0.651 0.459 4.82 0.528 0.339 4.06 6.276 0.9963 3179674 Maybridge4_000125 COc1cc2c(=O)oc(nc2c(OC)c1OC)c3c(C)onc3c4c(F)cccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F16 compound treatment 0.663 0.471 4.95 0.611 0.422 5.05 7.0673 0.9999 3063184 Maybridge4_000126 Brc1ccc(s1)c2cnc3ccccc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F17 compound treatment 0.351 0.159 1.67 0.378 0.189 2.26 2.779 0.9889 1216365 Maybridge4_000127 Clc1ccc(Oc2nc(Oc3ccc(Cl)cc3)nc(n2)N4CCSCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F18 compound treatment 0.117 -0.075 -0.79 0.15 -0.0391 -0.47 -0.8877 -0.9689 1464435 Maybridge4_000128 CC(C)(C)c1ccc(Oc2ncccc2C(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F19 compound treatment 0.216 0.024 0.25 0.215 0.0259 0.31 0.3974 0.9946 1281583 Maybridge4_000129 Cc1nn(nc1C(=O)NC(=O)N2CCSCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F20 compound treatment 0.336 0.144 1.51 0.285 0.0959 1.15 1.8808 0.9908 3063185 Maybridge4_000130 CC(C)(C(=O)Oc1ccccc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F21 compound treatment 0.278 0.086 0.9 0.333 0.144 1.72 1.8562 0.9546 3179675 Maybridge4_000131 CC(C)(C)SCCNc1nc(Sc2ccc(Cl)cc2)nc(n1)N3CCSCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F22 compound treatment 0.041 -0.151 -1.59 0.041 -0.148 -1.77 -2.3743 -0.9985 3063186 Maybridge4_000132 CSc1nn(C)c2cnn(C)c(=O)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F23 mock treatment 0.182 -0.01 -0.11 0.156 -0.0331 -0.4 -0.3542 -0.8653 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 F24 mock treatment 0.181 -0.011 -0.12 0.171 -0.0181 -0.22 -0.2347 -0.9573 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G01 compound treatment 0.136 -0.056 -0.59 0.139 -0.0501 -0.6 -0.8397 -1.0 3063187 Maybridge4_000133 Cc1ccccc1N2CCNCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G02 compound treatment 0.426 0.234 2.46 0.501 0.312 3.73 4.3766 0.9794 3179676 Maybridge4_000134 c1ccc(nc1)c2nnc([nH]2)c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G03 compound treatment 0.179 -0.013 -0.14 0.184 -0.00506 -0.06 -0.1396 -0.9328 1229940 Maybridge4_000135 OC(CNCc1ccc(Cl)cc1Cl)Cn2c(cc3ccccc23)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G04 compound treatment 0.902 0.71 7.46 0.821 0.632 7.56 10.6189 1.0 3063224 Maybridge4_000136 NC(=O)NC(=S)NC(=O)c1ccccc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G05 compound treatment 0.492 0.3 3.15 0.441 0.252 3.01 4.3591 0.9998 3063225 Maybridge4_000137 FC(F)(F)c1cccc(NC(=S)NCCNc2nccc(n2)C(F)(F)F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G06 compound treatment 0.628 0.436 4.58 0.52 0.331 3.96 6.0375 0.9974 1407734 Maybridge4_000138 Cc1cccc(C)c1NC(=S)N2CCCc3cccc(C)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G07 compound treatment 0.155 -0.037 -0.39 0.17 -0.0191 -0.23 -0.4363 -0.9677 3063226 Maybridge4_000139 Cc1nc(ccc1C(=O)O)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G08 compound treatment 0.117 -0.075 -0.79 0.134 -0.0551 -0.66 -1.0231 -0.996 3063227 Maybridge4_000140 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2cccc(c2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G09 compound treatment 0.168 -0.024 -0.25 0.172 -0.0171 -0.2 -0.3228 -0.9945 1525364 Maybridge4_000141 COc1ccccc1NC(=O)N2CCCN(Cc3ccc(F)cc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G10 compound treatment 0.226 0.034 0.36 0.279 0.0899 1.08 1.0132 0.8937 3179677 Maybridge4_000142 Cc1cccc2c(=O)n(CCNCc3ccccc3)c(C)nc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G11 compound treatment 0.46 0.268 2.81 0.454 0.265 3.17 4.2315 0.9982 1397176 Maybridge4_000143 Cc1cc(c(C)cc1Cl)S(=O)(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G12 compound treatment 0.537 0.345 3.62 0.49 0.301 3.6 5.1079 1.0 1223333 Maybridge4_000144 COc1cc2CCN=C(c3c(C)onc3c4ccccc4)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G13 compound treatment 0.434 0.242 2.54 0.404 0.215 2.57 3.6154 1.0 3179678 Maybridge4_000145 Clc1ccc(cc1)S(=O)(=O)NCCNc2ncnc3scc(c4ccccc4)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G14 compound treatment 0.346 0.154 1.62 0.328 0.139 1.66 2.3189 0.9999 3063228 Maybridge4_000146 FC(F)(F)c1cc(NC(=O)CSC(=O)c2ccco2)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G15 compound treatment 0.368 0.176 1.85 0.319 0.13 1.55 2.4061 0.9963 1479980 Maybridge4_000147 COc1cccc(OC)c1C(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G16 compound treatment 1.02 0.828 8.7 0.999 0.81 9.69 13.0011 0.9985 3063229 Maybridge4_000148 FC(F)(F)c1cccc(c1)N2CCNC2=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G17 compound treatment 0.115 -0.077 -0.81 0.112 -0.0771 -0.92 -1.224 -0.9979 1615569 Maybridge4_000149 Ic1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G18 compound treatment 0.04 -0.152 -1.6 0.04 -0.149 -1.78 -2.3902 -0.9985 3063230 Maybridge4_000150 FC(F)(F)c1cc(Br)ccc1/N=C/c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G19 compound treatment 0.113 -0.079 -0.83 0.13 -0.0591 -0.71 -1.0866 -0.9968 3179679 Maybridge4_000151 Fc1cccc(Cl)c1CN2CCN(CCCNC(=O)c3cccc(c3)C(F)(F)F)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G20 compound treatment 0.044 -0.148 -1.55 0.044 -0.145 -1.74 -2.3266 -0.9985 3063231 Maybridge4_000152 Cc1ccc(NC(=S)NC(C)(C)C)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G21 compound treatment 0.54 0.348 3.65 0.46 0.271 3.24 4.8764 0.9982 3179680 Maybridge4_000153 CSc1cccc(NC(=O)/C=C/c2ccc(cc2)C(C)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G22 compound treatment 1.1 0.908 9.54 1.02 0.831 9.94 13.7729 0.9998 3063232 Maybridge4_000154 S=C1NCN(Cc2cccs2)CN1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G23 mock treatment 0.192 -3.12E-5 0.0 0.149 -0.0401 -0.48 -0.3392 -0.7076 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 G24 mock treatment 0.18 -0.012 -0.13 0.192 0.00294 0.04 -0.0645 -0.4918 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H01 compound treatment 0.261 0.069 0.72 0.276 0.0869 1.04 1.2477 0.9844 3179681 Maybridge4_000155 Cc1ccc(SCc2ccccc2c3nc4ccccc4[nH]3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H02 compound treatment 0.138 -0.054 -0.57 0.175 -0.0141 -0.17 -0.5202 -0.8789 3063233 Maybridge4_000156 CN(C)/C=N/c1nnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H03 compound treatment 0.203 0.011 0.12 0.224 0.0349 0.42 0.377 0.8696 3179769 Maybridge4_000157 CCC(C)n1c(=O)[nH][nH]c1=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H04 compound treatment 0.204 0.012 0.13 0.177 -0.0121 -0.14 -0.0132 -0.0688 1039773 Maybridge4_000158 Cc1ccc(=O)n(Cc2ccccc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H05 compound treatment 0.098 -0.094 -0.99 0.109 -0.0801 -0.96 -1.3757 -0.9999 3179770 Maybridge4_000159 Fc1cccc(CSC2=NCN(CN2)C3CC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H06 compound treatment 0.267 0.075 0.79 0.292 0.103 1.23 1.4276 0.9766 3063234 Maybridge4_000160 FC(F)(F)c1cc(COc2ccc(CC#N)cc2)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H07 compound treatment 0.162 -0.03 -0.32 0.179 -0.0101 -0.12 -0.3082 -0.9128 1661120 Maybridge4_000161 COc1ccc(OC)c(c1)S(=O)(=O)NC2CCS(=O)(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H08 compound treatment 0.088 -0.104 -1.09 0.104 -0.0851 -1.02 -1.4922 -0.9994 3063235 Maybridge4_000162 CN(C)/C=N/c1ccc(Oc2cncc(Cl)c2)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H09 compound treatment 0.222 0.03 0.31 0.11 -0.0791 -0.95 -0.4463 -0.4477 3179771 Maybridge4_000163 Fc1ccc2sc(NC(=O)NC(=O)c3c(Cl)cccc3Cl)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H10 compound treatment 0.558 0.366 3.84 0.48 0.291 3.48 5.1792 0.9988 3063236 Maybridge4_000164 CC(=C)C(=O)Nc1ccc(Oc2ccccc2F)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H11 compound treatment 0.104 -0.088 -0.92 0.116 -0.0731 -0.87 -1.2719 -0.9996 3179772 Maybridge4_000165 Cc1cc(ccc1Cl)C2(O)CSc3nc4cc(ccc4n32)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H12 compound treatment 0.53 0.338 3.55 0.531 0.342 4.09 5.4028 0.9975 1316383 Maybridge4_000166 Cc1ccc(cc1)C(=O)Oc2c(C)cc(cc2C)c3nn(C)c(=O)c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H13 compound treatment 1.129 0.937 9.84 0.937 0.748 8.95 13.2861 0.9989 1008407 Maybridge4_000167 Clc1ccc(OCOc2ccc(Cl)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H14 compound treatment 0.229 0.037 0.39 0.18 -0.00906 -0.11 0.1979 0.4909 3179773 Maybridge4_000168 CN(C)/C=C(\Sc1nnc(N)s1)/C(=O)Nc2ccc(F)c(F)c2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H15 compound treatment 0.187 -0.00503 -0.05 0.177 -0.0121 -0.14 -0.1394 -0.9071 3063237 Maybridge4_000169 O=c1ncn(Cc2cccs2)cc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H16 compound treatment 0.18 -0.012 -0.13 0.163 -0.0261 -0.31 -0.3098 -0.9209 1639465 Maybridge4_000170 COC(=O)CNC(=O)c1cccnc1Sc2cc(OC)ccc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H17 compound treatment 0.761 0.569 5.98 0.699 0.51 6.1 8.5396 0.9999 3063238 Maybridge4_000171 CCOC(=O)c1cc(CC)sc1NC(=S)Nc2ccccc2C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H18 compound treatment 0.107 -0.085 -0.89 0.147 -0.0421 -0.5 -0.9873 -0.9632 1639248 Maybridge4_000172 CN(N1CC(C)(C)C1=O)c2cnn(c3ccc(C)cc3)c(=O)c2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H19 compound treatment 0.177 -0.015 -0.16 0.213 0.0239 0.29 0.0909 0.2779 1494290 Maybridge4_000173 CC1CN(CC(C)O1)C(=O)NC(=O)c2nn(nc2C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H20 compound treatment 0.498 0.306 3.21 0.361 0.172 2.06 3.7269 0.9768 3179774 Maybridge4_000174 Cc1ccc(/C=C/c2onc3c(=O)[nH]nc(C)c23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H21 compound treatment 0.376 0.184 1.93 0.385 0.196 2.34 3.0239 0.9954 3179775 Maybridge4_000175 Cc1cc(=O)oc2[nH]nc(CSc3ccc(Cl)cc3)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H22 compound treatment 0.438 0.246 2.58 0.398 0.209 2.5 3.5943 0.9999 1137912 Maybridge4_000176 CCOC(=O)c1c(C)c(C#N)c(NC(=O)c2ccc(Cl)cc2Cl)n1c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H23 mock treatment 0.162 -0.03 -0.32 0.216 0.0269 0.32 0.0049 0.0108 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 H24 mock treatment 0.194 0.00197 0.02 0.204 0.0149 0.18 0.141 0.7837 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I01 compound treatment 0.156 -0.036 -0.38 0.166 -0.0231 -0.28 -0.4627 -0.988 3179776 Maybridge4_000177 OC(=O)C1CCc2ccccc2O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I02 compound treatment 0.151 -0.041 -0.43 0.15 -0.0391 -0.47 -0.6352 -0.9992 1265650 Maybridge4_000178 OC(=O)c1ccccc1NC(=O)c2ccccc2NC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I03 compound treatment 0.237 0.045 0.47 0.291 0.102 1.22 1.1964 0.9147 3063239 Maybridge4_000179 COc1ccc(CC/N=C/c2ccc(Oc3nccc(n3)C(F)(F)F)cc2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I04 compound treatment 0.162 -0.03 -0.32 0.141 -0.0481 -0.58 -0.6296 -0.96 3179777 Maybridge4_000180 Cc1ccc(Nc2nc3ccccc3s2)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I05 compound treatment 0.399 0.207 2.17 0.348 0.159 1.9 2.8817 0.9978 3179778 Maybridge4_000181 FC(F)(F)c1ccnc(NCCNC(=S)NCc2ccco2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I06 compound treatment 0.732 0.54 5.67 0.721 0.532 6.36 8.5103 0.9983 3063240 Maybridge4_000182 Cc1ccc2N(CCCc2c1)C(=S)Nc3cccc(c3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I07 compound treatment 0.28 0.088 0.92 0.241 0.0519 0.62 1.0927 0.9814 3179779 Maybridge4_000183 Cc1ccc(cc1)S(=O)(=O)NCCNc2nccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I08 compound treatment 0.42 0.228 2.39 0.408 0.219 2.62 3.5453 0.999 3063241 Maybridge4_000184 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3[nH]nnc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I09 compound treatment 0.246 0.054 0.57 0.245 0.0559 0.67 0.874 0.9966 3179780 Maybridge4_000185 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I10 compound treatment 0.403 0.211 2.22 0.359 0.17 2.03 3.0045 0.9991 3063242 Maybridge4_000186 Clc1ccc2scc(/C(=C/c3cccs3)/C#N)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I11 compound treatment 0.11 -0.082 -0.86 0.129 -0.0601 -0.72 -1.1173 -0.9959 3179781 Maybridge4_000187 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)C=CC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I12 compound treatment 0.14 -0.052 -0.55 0.096 -0.0931 -1.11 -1.1737 -0.9463 3063243 Maybridge4_000188 FC(F)(F)c1cc(NC=C2C(=O)NC(=S)NC2=O)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I13 compound treatment 0.775 0.583 6.12 0.734 0.545 6.52 8.9397 0.9995 3179782 Maybridge4_000189 Cc1nc(ccc1c2nnc(SCCCN3C(=O)c4ccccc4C3=O)o2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I14 compound treatment 0.156 -0.036 -0.38 0.175 -0.0141 -0.17 -0.3866 -0.9334 3179783 Maybridge4_000190 Cc1nc2ccc(Br)cc2c(=O)n1c3cc(ccc3N4CCOCC4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I15 compound treatment 0.294 0.102 1.07 0.268 0.0789 0.94 1.4251 0.998 1704168 Maybridge4_000191 CC1(C)C2CCC1(CS(=O)(=O)N3CCCN(CC3)c4nc5ccc(Cl)cc5s4)C(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I16 compound treatment 0.139 -0.053 -0.56 0.137 -0.0521 -0.62 -0.8343 -0.9984 3179784 Maybridge4_000192 COc1ccccc1NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I17 compound treatment 0.79 0.598 6.28 0.721 0.532 6.36 8.9411 1.0 1335897 Maybridge4_000193 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)N4CCc5ccccc5C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I18 compound treatment 0.14 -0.052 -0.55 0.132 -0.0571 -0.68 -0.8692 -0.9939 3063244 Maybridge4_000194 Cc1cccc(C)c1NC(=O)CSC(=O)c2sc3ccccc3c2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I19 compound treatment 0.155 -0.037 -0.39 0.159 -0.0301 -0.36 -0.5293 -0.9992 3179785 Maybridge4_000195 FC(F)(F)c1cc(Cl)c2nc(cn2c1)C(=O)NCCCN3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I20 compound treatment 0.347 0.155 1.63 0.372 0.183 2.19 2.6986 0.9894 3063245 Maybridge4_000196 Cc1ccc2ncc(nc2c1)c3ccc(Cl)c(C)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I21 compound treatment 0.661 0.469 4.93 0.607 0.418 5.0 7.0186 1.0 3063246 Maybridge4_000197 CN(C)/N=C(\C)/c1cc(Cl)cc(Cl)c1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I22 compound treatment 0.63 0.438 4.6 0.51 0.321 3.84 5.9678 0.996 3179786 Maybridge4_000198 Cc1nc2c(Br)cc(Br)cc2c(=O)n1Cc3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I23 mock treatment 0.188 -0.00403 -0.04 0.181 -0.00806 -0.1 -0.0981 -0.9317 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 I24 mock treatment 0.231 0.039 0.41 0.216 0.0269 0.32 0.5173 0.993 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J01 compound treatment 0.191 -0.00103 -0.01 0.225 0.0359 0.43 0.2964 0.6891 3063247 Maybridge4_000199 CSC1=NCCCN1C(=O)c2c(C)onc2c3ccccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J02 compound treatment 0.161 -0.031 -0.33 0.16 -0.0291 -0.35 -0.4763 -0.9995 3179787 Maybridge4_000200 FC(F)(F)C1=NN(C(=O)C1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J03 compound treatment 0.133 -0.059 -0.62 0.118 -0.0711 -0.85 -1.0396 -0.988 3063248 Maybridge4_000201 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J04 compound treatment 0.167 -0.025 -0.26 0.174 -0.0151 -0.18 -0.3133 -0.983 3179788 Maybridge4_000202 Cc1ccc(=O)n(n1)S(=O)(=O)c2ccc(F)cc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J05 compound treatment 0.45 0.258 2.71 0.428 0.239 2.86 3.9373 0.9996 3063249 Maybridge4_000203 CC(C)(C)NC(=S)NC1CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J06 compound treatment 0.189 -0.00303 -0.03 0.233 0.0439 0.53 0.3492 0.6631 1412882 Maybridge4_000204 CN(NS(=O)(=O)c1ccc(Cl)cc1)c2cnn(C)c(=O)c2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J07 compound treatment 0.223 0.031 0.33 0.162 -0.0271 -0.32 0.001 0.0023 3179789 Maybridge4_000205 CC1CN(CC(C)O1)C2=NCCN2S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J08 compound treatment 0.107 -0.085 -0.89 0.119 -0.0701 -0.84 -1.2242 -0.9995 3063250 Maybridge4_000206 COC(=O)c1cc(OC(=O)c2nn(nc2C)c3ccccc3)n(n1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J09 compound treatment 0.125 -0.067 -0.7 0.135 -0.0541 -0.65 -0.9552 -0.9991 3179790 Maybridge4_000207 FC(F)(F)c1ccc(OC(=O)NC(=O)c2c(Cl)cccc2Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J10 compound treatment 0.234 0.042 0.44 0.28 0.0909 1.09 1.081 0.9209 1174991 Maybridge4_000208 Clc1ccc(NC(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J11 compound treatment 0.855 0.663 6.96 0.74 0.551 6.59 9.5845 0.9996 1235401 Maybridge4_000209 Cc1cc(Oc2ccnc3cc(Cl)ccc23)ccc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J12 compound treatment 0.83 0.638 6.7 0.72 0.531 6.35 9.2297 0.9996 1558885 Maybridge4_000210 Cc1cc(cc(C)c1OC(=O)Nc2ccc(Cl)cc2)c3nn(C)c(=O)c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J13 compound treatment 0.468 0.276 2.9 0.389 0.2 2.39 3.741 0.9955 1586134 Maybridge4_000211 Clc1cccc(Cl)c1C(=O)NC(=O)N(Cc2ccccc2)C3CC4CCC3C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J14 compound treatment 0.194 0.00197 0.02 0.255 0.0659 0.79 0.5725 0.7254 3178204 Maybridge4_000212 CN(C)/C=C(\C(=O)Nc1ccc(F)c(F)c1F)/S(=O)(=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J15 compound treatment 0.161 -0.031 -0.33 0.158 -0.0311 -0.37 -0.4932 -0.9979 1175614 Maybridge4_000213 O=c1ncn(Cc2ccccn2)cc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J16 compound treatment 0.173 -0.019 -0.2 0.188 -0.00106 -0.01 -0.1503 -0.7506 1210252 Maybridge4_000214 Cc1ccc(cc1)C(=O)COc2cc(C)nc3nncn23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J17 compound treatment 0.168 -0.024 -0.25 0.155 -0.0341 -0.41 -0.4666 -0.9735 1235603 Maybridge4_000215 Fc1ccc(NC(=O)Cc2nn[nH]n2)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J18 compound treatment 0.107 -0.085 -0.89 0.098 -0.0911 -1.09 -1.4019 -0.9951 1578276 Maybridge4_000216 CN(c1cnn(c2ccc(C)cc2)c(=O)c1Cl)n3cccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J19 compound treatment 0.153 -0.039 -0.41 0.188 -0.00106 -0.01 -0.2989 -0.7287 1321013 Maybridge4_000217 COC(=O)c1sccc1OC(=O)c2nn(nc2C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J20 compound treatment 0.508 0.316 3.32 0.448 0.259 3.1 4.5372 0.9994 3063294 Maybridge4_000218 Cc1ccc(/C=C/c2onc3c(=O)n(C)nc(C)c23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J21 compound treatment 0.261 0.069 0.72 0.253 0.0639 0.76 1.0531 0.9996 3063295 Maybridge4_000219 CCCC/1=NN(C(=O)\C1=C\c2ccc(Cl)cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J22 compound treatment 0.31 0.118 1.24 0.281 0.0919 1.1 1.6539 0.9982 3063296 Maybridge4_000220 CN(C(=O)CSc1ccc(cn1)C(F)(F)F)c2c3CCCCc3nn2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J23 mock treatment 0.289 0.097 1.02 0.234 0.0449 0.54 1.1003 0.9554 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 J24 mock treatment 0.188 -0.00403 -0.04 0.21 0.0209 0.25 0.1472 0.5794 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K01 compound treatment 0.253 0.061 0.64 0.234 0.0449 0.54 0.833 0.9962 1220864 Maybridge4_000221 CC(C)(C)c1cc(CN2C(=O)c3ccccc3C2=O)cc(c1O)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K02 compound treatment 0.176 -0.016 -0.17 0.201 0.0119 0.14 -0.0181 -0.0818 3063297 Maybridge4_000222 Cc1cc2CSC(SCc2cc1C)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K03 compound treatment 0.248 0.056 0.59 0.237 0.0479 0.57 0.8212 0.9999 3178205 Maybridge4_000223 FC(F)(F)Oc1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K04 compound treatment 0.452 0.26 2.73 0.391 0.202 2.42 3.6391 0.9981 3063298 Maybridge4_000224 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3oc(=O)ccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K05 compound treatment 0.317 0.125 1.31 0.3 0.111 1.33 1.8666 1.0 3178206 Maybridge4_000225 FC(F)(F)c1ccc(/C=C(\C#N)/c2cccc(c2)C(F)(F)F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K06 compound treatment 0.478 0.286 3.0 0.491 0.302 3.61 4.6782 0.9958 1672405 Maybridge4_000226 Clc1cccc(NC(=S)N2CCc3ccccc3C2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K07 compound treatment 0.139 -0.053 -0.56 0.15 -0.0391 -0.47 -0.7243 -0.9962 1231870 Maybridge4_000227 Fc1ccc(CN2CCCN(CC2)C(=O)Nc3cccc(Cl)c3Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K08 compound treatment 0.193 9.69E-4 0.01 0.157 -0.0321 -0.38 -0.2641 -0.6881 1729950 Maybridge4_000228 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2sc3ccccc3c2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K09 compound treatment 0.949 0.757 7.95 0.719 0.53 6.34 10.105 0.9937 3178207 Maybridge4_000229 Cc1nc(ccc1C(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K10 compound treatment 0.505 0.313 3.29 0.424 0.235 2.81 4.3119 0.997 1285643 Maybridge4_000230 Clc1ccc(cc1)N(CCc2ccccn2)S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K11 compound treatment 0.509 0.317 3.33 0.455 0.266 3.18 4.6038 0.9997 3063299 Maybridge4_000231 Clc1ccc(Cl)c(c1)n2ccnc2SCCCN3C(=O)c4ccccc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K12 compound treatment 0.167 -0.025 -0.26 0.209 0.0199 0.24 -0.0172 -0.0485 1594434 Maybridge4_000232 COc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCOCC3)c4ccc(Br)cc42 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K13 compound treatment 0.272 0.08 0.84 0.194 0.00494 0.06 0.6357 0.755 3063300 Maybridge4_000233 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K14 compound treatment 0.388 0.196 2.06 0.294 0.105 1.26 2.3431 0.9719 1540061 Maybridge4_000234 CN1C(NC(=O)c2ccccc12)C3CCC=CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K15 compound treatment 1.054 0.862 9.05 0.945 0.756 9.04 12.7968 1.0 3178208 Maybridge4_000235 CC(C)Nc1ncnc2scc(c3ccccc3)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K16 compound treatment 0.174 -0.018 -0.19 0.204 0.0149 0.18 -0.0075 -0.0289 3063301 Maybridge4_000236 S=C(NCCCN1CCOCC1)N2CC3CCC(CC3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K17 compound treatment 0.405 0.213 2.24 0.337 0.148 1.77 2.8332 0.9933 1631820 Maybridge4_000237 COc1ccc(NS(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2)c(OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K18 compound treatment 0.23 0.038 0.4 0.217 0.0279 0.33 0.5183 0.9961 3063302 Maybridge4_000238 Cc1cc(Oc2ccc(cc2n3cccc3)C(F)(F)F)cc(C)c1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K19 compound treatment 0.136 -0.056 -0.59 0.093 -0.0961 -1.15 -1.2288 -0.9517 3178209 Maybridge4_000239 FC(F)(F)c1cnc(N2CCC(CC2)N3C(=O)CC4(CCCC4)C3=O)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K20 compound treatment 0.418 0.226 2.37 0.219 0.0299 0.36 1.9314 0.8047 3063303 Maybridge4_000240 Clc1ccc(SC(=O)c2cccnc2Oc3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K21 compound treatment 0.15 -0.042 -0.44 0.147 -0.0421 -0.5 -0.668 -0.9979 1673449 Maybridge4_000241 O=C1CCCCCCCCCCC1CN2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K22 compound treatment 0.192 -3.12E-5 0.0 0.202 0.0129 0.15 0.1092 0.7056 1443277 Maybridge4_000242 Nc1ccccc1C(=O)NCCc2ccncc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K23 mock treatment 0.157 -0.035 -0.37 0.179 -0.0101 -0.12 -0.3453 -0.8919 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 K24 mock treatment 0.204 0.012 0.13 0.178 -0.0111 -0.13 -0.0047 -0.0258 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L01 compound treatment 0.189 -0.00303 -0.03 0.19 9.38E-4 0.01 -0.0146 -0.4319 1275035 Maybridge4_000243 COC(=O)c1ccc(C)c(NC(=O)c2ccncc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L02 compound treatment 0.337 0.145 1.52 0.339 0.15 1.79 2.3451 0.9967 3178210 Maybridge4_000244 CN(C)/C=N/S(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L03 compound treatment 0.392 0.2 2.1 0.395 0.206 2.46 3.2273 0.9968 1520487 Maybridge4_000245 Clc1ccc(cc1)C(=O)CNC(=O)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L04 compound treatment 0.08 -0.112 -1.18 0.084 -0.105 -1.26 -1.7208 -0.9995 3063304 Maybridge4_000246 Fc1ccc(cc1F)C2=CSC3=NCCCN23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L05 compound treatment 0.112 -0.08 -0.84 0.097 -0.0921 -1.1 -1.3732 -0.9911 3178211 Maybridge4_000247 CCC1(CC)N/C(=N/c2ccc(F)cc2F)/SC1=C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L06 compound treatment 0.716 0.524 5.5 0.764 0.575 6.88 8.7553 0.9939 3063305 Maybridge4_000248 Cn1ncc(SCc2ccccc2)c(Cl)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L07 compound treatment 0.093 -0.099 -1.04 0.103 -0.0861 -1.03 -1.4636 -1.0 3178212 Maybridge4_000249 Cc1ccc(/N=C\2/NC(C)(C)C(=C)S2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L08 compound treatment 0.199 0.00697 0.07 0.175 -0.0141 -0.17 -0.0672 -0.3663 3178213 Maybridge4_000250 CC(=O)Nc1ccc(Oc2cncc(Cl)c2)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L09 compound treatment 0.227 0.035 0.37 0.214 0.0249 0.3 0.4707 0.9947 3063306 Maybridge4_000251 CCOC(=S)SCc1ccc(cc1)C(=O)Oc2ccc(F)cc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L10 compound treatment 1.032 0.84 8.82 0.919 0.73 8.73 12.4134 1.0 3178214 Maybridge4_000252 CC1(C)CN(C(=S)Nc2cccc(Cl)c2)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L11 compound treatment 0.18 -0.012 -0.13 0.124 -0.0651 -0.78 -0.6398 -0.8113 3063307 Maybridge4_000253 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L12 compound treatment 0.218 0.026 0.27 0.185 -0.00406 -0.05 0.1585 0.5721 1389325 Maybridge4_000254 Cc1cc(cc(C)c1OCC(=O)NN)c2nn(C)c(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L13 compound treatment 0.488 0.296 3.11 0.523 0.334 4.0 5.0232 0.9923 3063308 Maybridge4_000255 CSc1ccc(OCOc2ccc(SC)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L14 compound treatment 0.097 -0.095 -1.0 0.129 -0.0601 -0.72 -1.2139 -0.987 3178215 Maybridge4_000256 CCOC(=O)c1c(F)c(F)c(c(F)c1F)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L15 compound treatment 0.255 0.063 0.66 0.219 0.0299 0.36 0.7209 0.9585 3178216 Maybridge4_000257 CN1C(NC(=O)c2cc(Cl)ccc12)c3ccc(C#N)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L16 compound treatment 0.21 0.018 0.19 0.154 -0.0351 -0.42 -0.1632 -0.3548 1354966 Maybridge4_000258 Cc1ccc(Oc2ncccc2C(=O)NCC(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L17 compound treatment 0.167 -0.025 -0.26 0.166 -0.0231 -0.28 -0.381 -0.9997 3178217 Maybridge4_000259 NC(=O)Nc1ccc2[nH]ncc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L18 compound treatment 0.168 -0.024 -0.25 0.168 -0.0211 -0.25 -0.3567 -1.0 3063309 Maybridge4_000260 COc1cc(C)nc2nc(nn12)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L19 compound treatment 1.334 1.14 11.99 1.367 1.18 14.09 18.4464 0.9968 3178218 Maybridge4_000261 CSc1nncc(n1)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L20 compound treatment 0.533 0.341 3.58 0.429 0.24 2.87 4.5621 0.994 1483914 Maybridge4_000262 Cc1ccc(cc1)c2cc(n[nH]2)c3c(C)nn(C)c(=O)c3N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L21 compound treatment 0.224 0.032 0.34 0.205 0.0159 0.19 0.3722 0.9641 1521640 Maybridge4_000263 Nc1ccccc1C(=O)NC2CCCCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L22 compound treatment 0.351 0.159 1.67 0.343 0.154 1.84 2.4829 0.9988 3178219 Maybridge4_000264 Cc1nc(cs1)c2cc(C#N)c(Sc3cccc(c3)C(F)(F)F)nc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L23 mock treatment 0.208 0.016 0.17 0.181 -0.00806 -0.1 0.0504 0.2604 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 L24 mock treatment 0.177 -0.015 -0.16 0.185 -0.00406 -0.05 -0.146 -0.8839 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M01 compound treatment 0.198 0.00597 0.06 0.204 0.0149 0.18 0.1707 0.9013 3063310 Maybridge4_000265 Oc1ccccc1/N=C/C=N/c2ccccc2O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M02 compound treatment 0.2 0.00797 0.08 0.218 0.0289 0.35 0.304 0.8535 3178220 Maybridge4_000266 CN(CCC#N)c1ccc(cc1)C2SCc3cc(C)c(C)cc3CS2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M03 compound treatment 0.254 0.062 0.65 0.184 -0.00506 -0.06 0.4174 0.6385 3063311 Maybridge4_000267 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M04 compound treatment 0.183 -0.00903 -0.09 0.196 0.00694 0.08 -0.0084 -0.0665 3178221 Maybridge4_000268 Cc1onc(c1C(=O)N2CCCc3cccc(C)c23)c4c(Cl)cccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M05 compound treatment 0.057 -0.135 -1.42 0.048 -0.141 -1.69 -2.1962 -0.9963 1280324 Maybridge4_000269 Cc1c(Cl)cccc1NC(=S)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M06 compound treatment 0.507 0.315 3.31 0.45 0.261 3.12 4.5467 0.9996 1592820 Maybridge4_000270 Cc1ccccc1NC(=S)Nc2ccccc2C(=O)Nc3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M07 compound treatment 0.111 -0.081 -0.85 0.122 -0.0671 -0.8 -1.1691 -0.9996 3178222 Maybridge4_000271 Cc1nc(ccc1C(=O)Oc2ccc(OC(F)(F)F)cc2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M08 compound treatment 0.885 0.693 7.28 0.714 0.525 6.28 9.5874 0.9973 1647940 Maybridge4_000272 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3cc(Cl)ccc3n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M09 compound treatment 0.789 0.597 6.27 0.636 0.447 5.35 8.2145 0.9969 3178223 Maybridge4_000273 Cc1ccc(NC(=S)N2CCC(CC2)Nc3nccc(n3)C(F)(F)F)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M10 compound treatment 0.529 0.337 3.54 0.472 0.283 3.39 4.8962 0.9998 1291651 Maybridge4_000274 CC(C)c1ccc(cc1)N(CCc2ccccn2)S(=O)(=O)c3ccc(C)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M11 compound treatment 0.952 0.76 7.98 0.706 0.517 6.18 10.0173 0.9921 3178308 Maybridge4_000275 FC(F)(F)c1cccnc1NCCNc2ncnc3scc(c4ccccc4)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M12 compound treatment 0.256 0.064 0.67 0.233 0.0439 0.53 0.8468 0.9926 3178309 Maybridge4_000276 Fc1ccc(cc1)C2CN3C(=N2)C=Cc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M13 compound treatment 0.354 0.162 1.7 0.309 0.12 1.43 2.2175 0.9964 1327290 Maybridge4_000277 COC(=O)c1cc(C#N)c(C)nc1Sc2nccn2c3cc(Cl)ccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M14 compound treatment 0.345 0.153 1.61 0.328 0.139 1.66 2.3115 0.9999 1331303 Maybridge4_000278 O=C1NC(Nc2ccccc12)C3CCC=CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M15 compound treatment 0.187 -0.00503 -0.05 0.181 -0.00806 -0.1 -0.1056 -0.9599 1371250 Maybridge4_000279 CC(C)NS(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M16 compound treatment 0.638 0.446 4.68 0.506 0.317 3.79 5.9933 0.9945 1643068 Maybridge4_000280 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)N2CC3CCC(CC3)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M17 compound treatment 0.422 0.23 2.42 0.388 0.199 2.38 3.3909 1.0 1732462 Maybridge4_000281 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M18 compound treatment 0.164 -0.028 -0.29 0.185 -0.00406 -0.05 -0.2425 -0.8128 1423781 Maybridge4_000282 Cc1cc(ccc1Cl)C(=O)c2cc3cc(Cl)ccc3o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M19 compound treatment 0.218 0.026 0.27 0.206 0.0169 0.2 0.3362 0.9893 3178310 Maybridge4_000283 Fc1cccc(Cl)c1CN2CCN(CCCNc3ncnc4scc(c5ccccc5)c34)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M20 compound treatment 0.244 0.052 0.55 0.225 0.0359 0.43 0.69 0.993 3063131 Maybridge4_000284 NNC(=O)c1cccnc1Oc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M21 compound treatment 0.202 0.00997 0.1 0.185 -0.00406 -0.05 0.0397 0.3436 3063132 Maybridge4_000285 Fc1ccc(/C=C/c2cccc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M22 compound treatment 0.375 0.183 1.92 0.34 0.151 1.81 2.6358 0.9995 3178311 Maybridge4_000286 Cc1ccc(SCCNC(=O)c2cccnc2Oc3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M23 mock treatment 0.234 0.042 0.44 0.184 -0.00506 -0.06 0.2689 0.6043 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 M24 mock treatment 0.181 -0.011 -0.12 0.197 0.00794 0.09 -0.0148 -0.0986 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N01 compound treatment 0.356 0.164 1.72 0.386 0.197 2.36 2.8838 0.9881 1041669 Maybridge4_000287 O=C(CSCC(=O)c1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N02 compound treatment 1.018 0.826 8.67 0.986 0.797 9.53 12.8763 0.9989 3178312 Maybridge4_000288 COC(=O)c1cccnc1SC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N03 compound treatment 0.918 0.726 7.62 0.962 0.773 9.25 11.9306 0.9954 3063133 Maybridge4_000289 Cc1ccccc1c2ncc(o2)c3ccc(Br)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N04 compound treatment 0.246 0.054 0.57 0.159 -0.0301 -0.36 0.1465 0.2182 3178313 Maybridge4_000290 Fc1ccc(cc1F)C2=NNC3=NCCN3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N05 compound treatment 0.135 -0.057 -0.6 0.115 -0.0741 -0.89 -1.0501 -0.9818 3178314 Maybridge4_000291 Clc1ccc(NC(=N)c2ccccc2)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N06 compound treatment 0.235 0.043 0.45 0.234 0.0449 0.54 0.6993 0.9962 1155893 Maybridge4_000292 CSc1nnc(SC)n1CCNC(=O)c2c(Cl)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N07 compound treatment 0.099 -0.093 -0.98 0.087 -0.102 -1.22 -1.5544 -0.9939 3178315 Maybridge4_000293 CCc1cccc(CC)c1/N=C\2/NC(C)(C)C(=C)S2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N08 compound treatment 0.355 0.163 1.71 0.285 0.0959 1.15 2.0219 0.9811 3178316 Maybridge4_000294 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC2=NN(C(=O)C2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N09 compound treatment 0.064 -0.128 -1.34 0.054 -0.135 -1.62 -2.0935 -0.9958 1286323 Maybridge4_000295 COC(=O)c1sc2ccccc2c1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N10 compound treatment 0.158 -0.034 -0.36 0.16 -0.0291 -0.35 -0.4986 -0.9999 1418804 Maybridge4_000296 Nc1ccccc1Nc2nc(=O)n(Cc3ccc(Cl)cc3)cc2C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N11 compound treatment 0.408 0.216 2.27 0.349 0.16 1.91 2.957 0.9964 1326126 Maybridge4_000297 Cc1ccc(COn2c(nc3ccccc3c2=O)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N12 compound treatment 0.147 -0.045 -0.47 0.141 -0.0481 -0.58 -0.741 -0.9953 1242548 Maybridge4_000298 Cc1ccn2c(=O)c(cnc2c1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N13 compound treatment 0.691 0.499 5.24 0.694 0.505 6.04 7.9774 0.9975 3178317 Maybridge4_000299 N#Cc1ccc(OCOc2ccc(C#N)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N14 compound treatment 0.334 0.142 1.49 0.242 0.0529 0.63 1.5022 0.9273 3063134 Maybridge4_000300 CC(C)Sc1nnc(S)n1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N15 compound treatment 0.199 0.00697 0.07 0.211 0.0219 0.26 0.2373 0.8711 3178318 Maybridge4_000301 Cn1c(nc(=O)c2cc(Cl)ccc12)c3cc(Br)cs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N16 compound treatment 0.19 -0.00203 -0.02 0.203 0.0139 0.17 0.1028 0.6117 3178319 Maybridge4_000302 Cc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3N(CC=C)S(=O)(=O)c4ccc(C)cc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N17 compound treatment 0.601 0.409 4.3 0.586 0.397 4.75 6.3954 0.9987 3063135 Maybridge4_000303 Cc1onc(NC(=O)NC(=O)c2ccccc2F)c1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N18 compound treatment 0.252 0.06 0.63 0.195 0.00594 0.07 0.4956 0.7819 3063136 Maybridge4_000304 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccc(cn1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N19 compound treatment 0.161 -0.031 -0.33 0.15 -0.0391 -0.47 -0.5609 -0.9845 3178320 Maybridge4_000305 Clc1cc(Cl)c2nc(Oc3cccc(c3)N4CCOCC4)sc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N20 compound treatment 0.397 0.205 2.15 0.366 0.177 2.12 3.0191 1.0 3063137 Maybridge4_000306 CCOC(=O)c1nn(c2ccccc2)c(=N)c(C#N)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N21 compound treatment 0.22 0.028 0.29 0.202 0.0129 0.15 0.3172 0.9552 3178321 Maybridge4_000307 Cc1nn(nc1c2nnc(o2)c3ccc(Cl)c(Cl)c3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N22 compound treatment 0.22 0.028 0.29 0.22 0.0309 0.37 0.4694 0.9934 3178322 Maybridge4_000308 Cc1nc(cs1)c2cc(C#N)c(Oc3ccc(cc3)C(F)(F)F)nc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N23 mock treatment 0.214 0.022 0.23 0.204 0.0149 0.18 0.2895 0.992 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 N24 mock treatment 0.197 0.00497 0.05 0.212 0.0229 0.27 0.231 0.8268 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O01 compound treatment 0.166 -0.026 -0.27 0.167 -0.0221 -0.26 -0.38 -0.9998 3063138 Maybridge4_000309 Cn1cc(c(n1)C(F)(F)F)S(=O)(=O)NCc2ccc3OCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O02 compound treatment 0.165 -0.027 -0.28 0.197 0.00794 0.09 -0.1336 -0.4463 1336600 Maybridge4_000310 Clc1ccccc1n2c(n[nH]c2=S)C3CCCNC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O03 compound treatment 0.214 0.022 0.23 0.226 0.0369 0.44 0.4756 0.9541 3063139 Maybridge4_000311 Cc1cccc(Cl)c1NC(=O)N2CCCN(CC2)c3ncccc3C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O04 compound treatment 0.439 0.247 2.59 0.387 0.198 2.37 3.5087 0.999 3178323 Maybridge4_000312 CCOC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O05 compound treatment 0.168 -0.024 -0.25 0.15 -0.0391 -0.47 -0.5089 -0.9582 1600108 Maybridge4_000313 OC1CCN(CC1)C(=O)Nc2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O06 compound treatment 0.285 0.093 0.98 0.303 0.114 1.36 1.6544 0.9866 1675860 Maybridge4_000314 CCN(Cc1cc(OC)c(OC)c(OC)c1)C(=S)Nc2cccc(SC)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O07 compound treatment 0.221 0.029 0.3 0.212 0.0229 0.27 0.4092 0.9987 3063188 Maybridge4_000315 Cc1nc(ccc1C(=O)NCC=C)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O08 compound treatment 0.339 0.147 1.54 0.312 0.123 1.47 2.1315 0.9997 1638858 Maybridge4_000316 Cc1nc2cc(Cl)ccc2c(=O)n1CC3CCCO3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O09 compound treatment 0.191 -0.00103 -0.01 0.194 0.00494 0.06 0.0341 0.568 1730664 Maybridge4_000317 CCOC(=O)c1cc(C(=O)OC)c(C)nc1N2CCC(CC2)NC3CCCCC3O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O10 compound treatment 0.545 0.353 3.71 0.519 0.33 3.95 5.4126 0.9995 1134448 Maybridge4_000318 Fc1ccc(NC(=S)N2CCCCC2CCN3CCOCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O11 compound treatment 0.073 -0.119 -1.25 0.086 -0.103 -1.23 -1.7559 -1.0 3063189 Maybridge4_000319 OC(=O)/C=C/C(=O)NC1CCN(CC1)c2nccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O12 compound treatment 0.284 0.092 0.97 0.272 0.0829 0.99 1.3847 0.9999 3178324 Maybridge4_000320 C1C(N=C2C=Cc3ccccc3N12)c4ccc5ccccc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O13 compound treatment 0.278 0.086 0.9 0.229 0.0399 0.48 0.9763 0.9557 1152090 Maybridge4_000321 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O14 compound treatment 0.242 0.05 0.52 0.243 0.0539 0.65 0.8274 0.9947 1502131 Maybridge4_000322 Nc1n(nc2cc(O)nc(O)c12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O15 compound treatment 0.101 -0.091 -0.96 0.118 -0.0711 -0.85 -1.2772 -0.9983 1406030 Maybridge4_000323 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2ccccc2C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O16 compound treatment 0.382 0.19 2.0 0.311 0.122 1.46 2.4424 0.9882 1015155 Maybridge4_000324 O=c1ccc(=O)n([nH]1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O17 compound treatment 0.443 0.251 2.64 0.505 0.316 3.78 4.5367 0.9845 3178325 Maybridge4_000325 Cc1nc(nc(NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1Cl)c4ccccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O18 compound treatment 0.17 -0.022 -0.23 0.147 -0.0421 -0.5 -0.5195 -0.9378 3063190 Maybridge4_000326 Cc1cc(NC(=S)NC(C)(C)C)ccc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O19 compound treatment 0.208 0.016 0.17 0.22 0.0309 0.37 0.3803 0.9359 1373262 Maybridge4_000327 S=C(NC1CC1)N2CCCN(Cc3cccc4ccccc34)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O20 compound treatment 0.205 0.013 0.14 0.242 0.0529 0.63 0.5442 0.84 3178326 Maybridge4_000328 N#Cc1cccnc1Oc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O21 compound treatment 0.222 0.03 0.31 0.199 0.00994 0.12 0.3066 0.9114 3178327 Maybridge4_000329 Cc1cc(C(=O)NN)c2cc(Br)ccc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O22 compound treatment 0.29 0.098 1.03 0.287 0.0979 1.17 1.5561 0.9979 3063191 Maybridge4_000330 CC(C)(C)NC(=S)Nc1cc(ccc1N2CCCCC2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O23 mock treatment 0.158 -0.034 -0.36 0.206 0.0169 0.2 -0.1094 -0.2664 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 O24 mock treatment 0.201 0.00897 0.09 0.218 0.0289 0.35 0.3114 0.8679 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P01 compound treatment 0.125 -0.067 -0.7 0.12 -0.0691 -0.83 -1.0821 -0.9968 3178328 Maybridge4_000331 Fc1ccc(cc1Cl)C(=O)NC(=O)Nc2nnc(s2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P02 compound treatment 0.097 -0.095 -1.0 0.098 -0.0911 -1.09 -1.4762 -0.999 3178329 Maybridge4_000332 CN(C)/C=C/1\C(=O)c2ccc(Cl)cc2N(Cc3c(F)cccc3Cl)S1(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P03 compound treatment 0.951 0.759 7.97 0.965 0.776 9.28 12.201 0.9971 3063192 Maybridge4_000333 Fc1ccccc1C(=O)NC(=O)OCc2ccc(Cl)cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P04 compound treatment 0.149 -0.043 -0.45 0.153 -0.0361 -0.43 -0.6247 -0.9997 3063193 Maybridge4_000334 CN1N=C(CC1=O)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P05 compound treatment 0.239 0.047 0.49 0.237 0.0479 0.57 0.7544 0.9972 3178330 Maybridge4_000335 Clc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)NCCCn3ccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P06 compound treatment 0.194 0.00197 0.02 0.184 -0.00506 -0.06 -0.0282 -0.4407 3063194 Maybridge4_000336 CN(C)/C=N/c1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P07 compound treatment 0.143 -0.049 -0.51 0.172 -0.0171 -0.2 -0.5085 -0.9179 3178331 Maybridge4_000337 CSC1=NCCN1CC(=O)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P08 compound treatment 0.073 -0.119 -1.25 0.071 -0.118 -1.41 -1.8828 -0.9981 3178429 Maybridge4_000338 Oc1c(C(=O)c2ccccc2)c(CS(=O)(=O)c3ccc(cn3)C(F)(F)F)nn1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P09 compound treatment 0.465 0.273 2.87 0.388 0.199 2.38 3.7102 0.9957 3063195 Maybridge4_000339 FC(F)(F)c1ccc2[nH]c(SCc3cccc(C#N)c3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P10 compound treatment 0.329 0.137 1.44 0.378 0.189 2.26 2.6156 0.9762 3178430 Maybridge4_000340 COc1ccccc1N2CC(C)(C)C(=O)N(C(=O)c3ccc(C)cc3)C2=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P11 compound treatment 0.264 0.072 0.76 0.312 0.123 1.47 1.5745 0.9521 1567114 Maybridge4_000341 Brc1ccc(COn2c(nc3ccccc3c2=O)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P12 compound treatment 0.793 0.601 6.31 0.749 0.56 6.7 9.2002 0.9996 1250229 Maybridge4_000342 CCCCN1C(C(=O)N(C1=O)c2nnc(s2)C(C)(C)C)c3ccc(Cl)c(Cl)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P13 compound treatment 0.188 -0.00403 -0.04 0.184 -0.00506 -0.06 -0.0728 -0.9847 3063196 Maybridge4_000343 COC(=O)/C=c/1\sc2nc3cc(Cl)c(Cl)cc3n2c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P14 compound treatment 0.399 0.207 2.17 0.321 0.132 1.58 2.6533 0.9877 3178431 Maybridge4_000344 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCOC(=O)c2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P15 compound treatment 0.274 0.082 0.86 0.312 0.123 1.47 1.6488 0.9674 3063197 Maybridge4_000345 CC(C)(C)SCCNc1nc(Oc2ccc(F)cc2)nc(Oc3ccc(F)cc3)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P16 compound treatment 0.138 -0.054 -0.57 0.143 -0.0461 -0.55 -0.791 -0.9999 3178432 Maybridge4_000346 N=C1CC(=O)N=C2SC(=NN21)C3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P17 compound treatment 0.046 -0.146 -1.53 0.048 -0.141 -1.69 -2.2779 -0.9989 3063198 Maybridge4_000347 COC(=O)/C(=C/N(C)C)/Sc1cc(C)c(Cl)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P18 compound treatment 0.127 -0.065 -0.68 0.121 -0.0681 -0.81 -1.0588 -0.9962 3178433 Maybridge4_000348 CSc1nc(C)nc(Sc2ccccc2)c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P19 compound treatment 0.144 -0.048 -0.5 0.175 -0.0141 -0.17 -0.4757 -0.8945 3178434 Maybridge4_000349 Cc1cc(Oc2nc3cc(Cl)ccc3s2)c4cc(Cl)ccc4n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P20 compound treatment 0.328 0.136 1.43 0.361 0.172 2.06 2.4644 0.9841 1222979 Maybridge4_000350 CSC1=NN(C)c2cnn(C)c(=O)c2S1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P21 compound treatment 0.177 -0.015 -0.16 0.188 -0.00106 -0.01 -0.1206 -0.7616 1579106 Maybridge4_000351 O=C(CC#N)NCc1ccccn1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P22 compound treatment 0.142 -0.05 -0.53 0.13 -0.0591 -0.71 -0.8712 -0.9894 1689187 Maybridge4_000352 Clc1ccc(SCC(=O)c2ccc3NC(=O)CCc3c2)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P23 mock treatment 0.22 0.028 0.29 0.209 0.0199 0.24 0.3764 0.9947 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2049 P24 mock treatment 0.193 9.69E-4 0.01 0.225 0.0359 0.43 0.3112 0.7236 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A01 compound treatment 0.173 -0.0655 -0.69 0.182 -0.0736 -0.88 -1.1086 -0.9925 1580862 Maybridge4_000705 CC1CC(C)CN(C1)c2ccc(NC(=O)c3ccc(Cl)cc3)cc2C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A02 compound treatment 0.264 0.0255 0.27 0.371 0.115 1.38 1.1662 0.8289 3063159 Maybridge4_000706 Cc1nn(C)c(Cl)c1S(=O)(=O)Nc2ccc(C)cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A03 compound treatment 0.196 -0.0425 -0.45 0.197 -0.0586 -0.7 -0.8108 -0.9762 3178926 Maybridge4_000707 CN(C)/C=N/S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A04 compound treatment 0.703 0.465 4.88 0.78 0.524 6.27 7.8867 0.9923 3178927 Maybridge4_000708 Clc1ccc(NC(=S)N2CCCC2c3cccs3)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A05 compound treatment 0.763 0.525 5.51 0.838 0.582 6.97 8.8229 0.9932 3063160 Maybridge4_000709 Cn1nccc1c2cc(F)cc(F)c2O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A06 compound treatment 0.195 -0.0435 -0.46 0.223 -0.0326 -0.39 -0.5983 -0.9969 3178928 Maybridge4_000710 O=C(NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A07 compound treatment 0.871 0.633 6.64 0.874 0.618 7.4 9.9296 0.9986 3063161 Maybridge4_000711 Fc1cccc(Cl)c1COC(=O)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A08 compound treatment 0.108 -0.13 -1.37 0.087 -0.169 -2.02 -2.395 -0.9823 3063162 Maybridge4_000712 CN(C)/C=C/C(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A09 compound treatment 0.221 -0.0175 -0.18 0.274 0.0184 0.22 0.0263 0.0915 1674451 Maybridge4_000713 CN(NS(=O)(=O)c1cc(C)c(F)c(C)c1)c2cccc(Cl)c2C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A10 compound treatment 0.062 -0.176 -1.85 0.064 -0.192 -2.29 -2.9312 -0.9945 3063163 Maybridge4_000714 CN(C)/C=C/1\SCc2ccccc2C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A11 compound treatment 0.555 0.317 3.32 0.567 0.311 3.73 4.9855 0.9984 3178929 Maybridge4_000715 Cc1onc(c1C(=O)c2ccc(F)cc2)c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A12 compound treatment 0.184 -0.0545 -0.57 0.23 -0.0256 -0.31 -0.6208 -0.957 1518860 Maybridge4_000716 COc1cccc(OC)c1C(=O)NN 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A13 compound treatment 0.247 0.00853 0.09 0.26 0.00444 0.05 0.1009 0.9688 1454624 Maybridge4_000717 CC1=C(O)C(=O)OC1c2c(F)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A14 compound treatment 0.42 0.182 1.91 0.454 0.198 2.37 3.027 0.9941 3178930 Maybridge4_000718 Cc1nc(COc2cc(C)c(Cl)c(C)c2Cl)cs1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A15 compound treatment 0.145 -0.0935 -0.98 0.152 -0.104 -1.24 -1.5703 -0.9933 3178931 Maybridge4_000719 Clc1ccc(NC(=O)C(C#N)C(=O)c2cccs2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A16 compound treatment 0.053 -0.185 -1.95 0.052 -0.204 -2.44 -3.0996 -0.9939 1203853 Maybridge4_000720 CC1N(CCc2sccc12)C(=S)NC(=O)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A17 compound treatment 0.194 -0.0445 -0.47 0.223 -0.0326 -0.39 -0.6057 -0.9959 3178932 Maybridge4_000721 CSc1nc(NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)nn1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A18 compound treatment 0.408 0.17 1.78 0.492 0.236 2.83 3.2593 0.9751 3063213 Maybridge4_000722 FC(F)(F)c1cccc(NC(=S)C(C#N)C(=O)N2CCCC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A19 compound treatment 0.193 -0.0455 -0.48 0.25 -0.00556 -0.07 -0.3847 -0.7979 3178933 Maybridge4_000723 Cc1nn(C)c(C)c1NC(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A20 compound treatment 0.153 -0.0855 -0.9 0.158 -0.0976 -1.17 -1.4601 -0.9916 1654657 Maybridge4_000724 Brc1ccc(Nc2ncnc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A21 compound treatment 0.24 0.00153 0.02 0.216 -0.0396 -0.47 -0.3233 -0.6827 1162031 Maybridge4_000725 Nc1n[nH]c(NC2CCCCNC2=O)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A22 compound treatment 0.075 -0.163 -1.72 0.087 -0.169 -2.02 -2.6401 -0.9968 3179020 Maybridge4_000726 C1CCN2C(=CSC2=NC1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A23 mock treatment 0.239 5.31E-4 0.01 0.233 -0.0226 -0.27 -0.1869 -0.6923 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 A24 mock treatment 0.24 0.00153 0.02 0.24 -0.0156 -0.19 -0.1203 -0.6436 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B01 compound treatment 0.442 0.204 2.14 0.471 0.215 2.58 3.3342 0.9957 1499601 Maybridge4_000727 S=C(Nc1ccccc1)Nc2ccccc2c3nc4ccccc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B02 compound treatment 1.103 0.865 9.08 1.095 0.839 10.04 13.5222 0.9987 1693956 Maybridge4_000728 CSc1cc(nc(c1)c2ccc(Cl)cc2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B03 compound treatment 0.142 -0.0965 -1.01 0.187 -0.0686 -0.82 -1.2965 -0.9945 3063216 Maybridge4_000729 CN1CNC(=NC1)SCc2ccc(C#N)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B04 compound treatment 0.243 0.00453 0.05 0.274 0.0184 0.22 0.1896 0.8403 3179021 Maybridge4_000730 FC(F)(F)c1ccccc1NC(=O)N/C=C/c2ccsc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B05 compound treatment 0.101 -0.137 -1.44 0.098 -0.158 -1.89 -2.3539 -0.9913 1138498 Maybridge4_000731 CN(C)c1ccc(cc1)C2Nc3cc(C)ccc3O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B06 compound treatment 0.046 -0.192 -2.02 0.047 -0.209 -2.5 -3.1938 -0.9945 3179022 Maybridge4_000732 CC1=CC(=O)N(C1=O)c2ccn(C)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B07 compound treatment 0.139 -0.0995 -1.04 0.161 -0.0946 -1.13 -1.5387 -0.9992 3179023 Maybridge4_000733 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B08 compound treatment 0.219 -0.0195 -0.2 0.243 -0.0126 -0.15 -0.2509 -0.9885 3063218 Maybridge4_000734 CCCc1c(cnn1c2ccccc2)c3nc(no3)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B09 compound treatment 0.315 0.0765 0.8 0.328 0.0724 0.87 1.1812 0.9993 3179024 Maybridge4_000735 FC(F)(F)c1cccc(NC2(CCCCCC2)C#N)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B10 compound treatment 0.125 -0.113 -1.19 0.127 -0.129 -1.54 -1.9303 -0.992 1512806 Maybridge4_000736 Cc1csc2c(ncnc12)N3CCSCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B11 compound treatment 0.213 -0.0255 -0.27 0.255 -5.63E-4 -0.01 -0.1939 -0.7247 1281080 Maybridge4_000737 CS(=O)(=O)N1CCCN2C1c3ccccc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B12 compound treatment 0.199 -0.0395 -0.41 0.23 -0.0256 -0.31 -0.5094 -0.9888 3179025 Maybridge4_000738 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2noc(n2)C3CCc4ccccc4O3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B13 compound treatment 0.599 0.361 3.79 0.649 0.393 4.71 6.006 0.9942 3063220 Maybridge4_000739 Cc1c(C)c(C)c(CSCc2n[nH]c(=S)n2c3ccc(F)cc3)c(C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B14 compound treatment 0.341 0.103 1.08 0.382 0.126 1.51 1.8311 0.9861 3179026 Maybridge4_000740 Cc1csc2ncnc(Sc3ccccc3NS(=O)(=O)c4ccc(F)cc4)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B15 compound treatment 0.195 -0.0435 -0.46 0.253 -0.00256 -0.03 -0.3445 -0.7529 3063222 Maybridge4_000741 CS/C(=N\C(=O)c1c(Cl)cccc1Cl)/N2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B16 compound treatment 0.219 -0.0195 -0.2 0.237 -0.0186 -0.22 -0.3016 -0.9991 1691561 Maybridge4_000742 Cc1csc2ncnc(N3CCN(CC3)C(=S)NCC4CC4)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B17 compound treatment 0.078 -0.16 -1.69 0.093 -0.163 -1.94 -2.567 -0.9975 1442583 Maybridge4_000743 Cc1ccc(C(=S)N)c(O)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B18 compound treatment 0.237 -0.00147 -0.02 0.321 0.0654 0.78 0.5427 0.693 1597708 Maybridge4_000744 COc1cc2CCNC(=O)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B19 compound treatment 0.308 0.0695 0.73 0.43 0.174 2.09 1.9921 0.901 3179027 Maybridge4_000745 FC(F)(F)Oc1ccc(cc1)n2c(=N)c(/N=C/c3ccc(cc3)C(F)(F)F)c(C#N)[nH]c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B20 compound treatment 0.34 0.102 1.07 0.396 0.14 1.68 1.9421 0.9759 1614161 Maybridge4_000746 Cc1csc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)c1C(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B21 compound treatment 0.476 0.238 2.49 0.49 0.234 2.8 3.7474 0.9983 3179028 Maybridge4_000747 Cc1csc(NC(=O)CSc2ccc(Cl)cc2)c1C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B22 compound treatment 0.554 0.316 3.31 0.636 0.38 4.55 5.5619 0.9878 3063278 Maybridge4_000748 NNC(=S)Nc1ccccc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B23 mock treatment 0.262 0.0235 0.25 0.254 -0.00156 -0.02 0.1615 0.6518 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 B24 mock treatment 0.237 -0.00147 -0.02 0.218 -0.0376 -0.45 -0.3287 -0.7309 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C01 compound treatment 0.261 0.0225 0.24 0.307 0.0514 0.62 0.6025 0.9138 3179029 Maybridge4_000749 Cc1cc(C)n(Cc2c(Cl)cccc2Cl)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C02 compound treatment 0.395 0.157 1.64 0.436 0.18 2.16 2.689 0.991 3063279 Maybridge4_000750 CC1SCC(CS1)NC(=O)c2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C03 compound treatment 0.183 -0.0555 -0.58 0.205 -0.0506 -0.6 -0.8397 -0.9998 3179030 Maybridge4_000751 CC(C)(C)n1cnnc1S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C04 compound treatment 0.32 0.0815 0.86 0.395 0.139 1.67 1.7852 0.952 3179031 Maybridge4_000752 Cc1c(cnn1c2ccc(Cl)cc2)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C05 compound treatment 0.169 -0.0695 -0.73 0.205 -0.0506 -0.6 -0.9437 -0.9957 3063283 Maybridge4_000753 CN(C)/C=c/1\s\c(=C\C(=O)c2cccs2)\[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C06 compound treatment 0.256 0.0175 0.18 0.302 0.0464 0.56 0.5231 0.8936 3179032 Maybridge4_000754 Fc1ccc(c2ccc(o2)c3ccnn3S(=O)(=O)c4ccc(F)cc4F)c(F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C07 compound treatment 0.243 0.00453 0.05 0.25 -0.00556 -0.07 -0.0134 -0.1639 3063284 Maybridge4_000755 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)N2CCSCC2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C08 compound treatment 0.141 -0.0975 -1.02 0.161 -0.0946 -1.13 -1.5239 -0.9988 3179033 Maybridge4_000756 NC(=O)N/C(=N/O)/CSCc1ccc(Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C09 compound treatment 0.825 0.587 6.16 0.846 0.59 7.06 9.3511 0.9977 3063285 Maybridge4_000757 Fc1cc(CSc2ccc(Cl)cc2)c3OCOCc3c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C10 compound treatment 0.247 0.00853 0.09 0.246 -0.00956 -0.11 -0.0175 -0.1207 1433051 Maybridge4_000758 CCOC(=O)Cc1nc(N)ncc1C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C11 compound treatment 0.414 0.176 1.84 0.436 0.18 2.16 2.8301 0.9969 1461982 Maybridge4_000759 Cc1onc(c1C(O)c2ccc(F)cc2)c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C12 compound treatment 0.261 0.0225 0.24 0.258 0.00244 0.03 0.1879 0.7883 1346508 Maybridge4_000760 COc1ccc2C(NN(C)c3cccc(F)c3C#N)OC(=O)c2c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C13 compound treatment 0.179 -0.0595 -0.62 0.176 -0.0796 -0.95 -1.1148 -0.9791 3179034 Maybridge4_000761 CN(C)/C=N/C(=S)NC1CC2CC1C=C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C14 compound treatment 0.168 -0.0705 -0.74 0.199 -0.0566 -0.68 -1.0019 -0.999 1675569 Maybridge4_000762 C(N1CC(CN(Cc2ccccc2)C1)c3nn[nH]n3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C15 compound treatment 1.052 0.814 8.54 1.065 0.809 9.68 12.8897 0.998 3063288 Maybridge4_000763 CNC(=O)n1cc(c(C)n1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C16 compound treatment 0.61 0.372 3.9 0.664 0.408 4.89 6.2146 0.9938 1260907 Maybridge4_000764 CC1N(CCc2sccc12)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C17 compound treatment 0.176 -0.0625 -0.66 0.219 -0.0366 -0.44 -0.7732 -0.9806 1246781 Maybridge4_000765 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccccc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C18 compound treatment 0.844 0.606 6.36 0.925 0.669 8.01 10.1605 0.9935 3179035 Maybridge4_000766 FC(F)(F)c1cccc(NC(=O)C(C#N)C(=S)Nc2ccccc2Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C19 compound treatment 0.213 -0.0255 -0.27 0.266 0.0104 0.12 -0.1008 -0.3416 3063289 Maybridge4_000767 CNC(=O)N1CCCC(Cn2cccc2)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C20 compound treatment 0.167 -0.0715 -0.75 0.214 -0.0416 -0.5 -0.8824 -0.98 1385501 Maybridge4_000768 Cc1ccc(cc1)c2csc(=N)n2c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C21 compound treatment 0.238 -4.69E-4 0.0 0.263 0.00744 0.09 0.0594 0.667 1144063 Maybridge4_000769 Clc1ccc(NC(=O)NC2CCCCNC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C22 compound treatment 0.095 -0.143 -1.51 0.093 -0.163 -1.94 -2.4408 -0.992 3179036 Maybridge4_000770 CC1CN=C(N1)SCc2c(C)c(C)c(C)c(C)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C23 mock treatment 0.275 0.0365 0.38 0.248 -0.00756 -0.09 0.2073 0.5259 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 C24 mock treatment 0.251 0.0125 0.13 0.211 -0.0446 -0.53 -0.2839 -0.517 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D01 compound treatment 0.119 -0.119 -1.25 0.115 -0.141 -1.68 -2.0764 -0.9896 3063290 Maybridge4_000771 CSC1=NCCN1Cc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D02 compound treatment 0.41 0.172 1.8 0.432 0.176 2.11 2.7666 0.9969 3179037 Maybridge4_000772 COC(=O)c1sc(cc1NC(=O)Nc2ccc(Cl)cc2)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D03 compound treatment 0.219 -0.0195 -0.2 0.218 -0.0376 -0.45 -0.4624 -0.9365 3063291 Maybridge4_000773 Cc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D04 compound treatment 0.187 -0.0515 -0.54 0.143 -0.113 -1.35 -1.3345 -0.9196 3179038 Maybridge4_000774 FC(F)(F)c1cc(SC(=O)N/C=C/c2ccsc2)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D05 compound treatment 0.388 0.15 1.57 0.507 0.251 3.01 3.2377 0.9541 1247834 Maybridge4_000775 CC(C)(C)CC(C)(C)N1CNC(=S)NC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D06 compound treatment 0.222 -0.0165 -0.17 0.236 -0.0196 -0.23 -0.2878 -0.9889 3179039 Maybridge4_000776 Cn1cc(Br)c(n1)N2C(=O)C=CC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D07 compound treatment 0.346 0.108 1.13 0.394 0.138 1.66 1.9698 0.9826 3179040 Maybridge4_000777 COc1cc(cc(OC)c1OC)C(O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D08 compound treatment 0.853 0.615 6.45 0.684 0.428 5.13 8.1885 0.9935 3063293 Maybridge4_000778 CCCc1nn(cc1C(=O)Nc2ccc(Cl)cc2)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D09 compound treatment 0.542 0.304 3.19 0.569 0.313 3.75 4.9059 0.9967 1432923 Maybridge4_000779 CC(NC(=O)c1c(C)onc1c2ccccc2Cl)c3ccc(C)cc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D10 compound treatment 0.209 -0.0295 -0.31 0.191 -0.0646 -0.77 -0.7651 -0.9194 3179041 Maybridge4_000780 FC(F)(F)c1c(cnn1c2ccc(Cl)cc2)C(=O)NCCc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D11 compound treatment 0.338 0.0995 1.05 0.306 0.0504 0.6 1.1659 0.9659 3179119 Maybridge4_000781 COc1cc(cc(OC)c1OC)C(=O)N2/C(=N/c3ccccc3Cl)/SC(=C)C2(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D12 compound treatment 0.322 0.0835 0.88 0.242 -0.0136 -0.16 0.5056 0.5667 3062512 Maybridge4_000782 COC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D13 compound treatment 0.206 -0.0325 -0.34 0.259 0.00344 0.04 -0.212 -0.6174 1164825 Maybridge4_000783 NNC(=O)Oc1ccccc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D14 compound treatment 0.254 0.0155 0.16 0.263 0.00744 0.09 0.1783 0.9594 3179120 Maybridge4_000784 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)/C=C/C(=O)O)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D15 compound treatment 0.283 0.0445 0.47 0.293 0.0374 0.45 0.6474 0.9998 3062514 Maybridge4_000785 Clc1cccc(Cl)c1C(=O)N=C2NCCCN2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D16 compound treatment 0.807 0.569 5.97 0.875 0.619 7.41 9.4627 0.9943 3179121 Maybridge4_000786 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D17 compound treatment 0.219 -0.0195 -0.2 0.195 -0.0606 -0.72 -0.657 -0.8726 3062515 Maybridge4_000787 CCOC(=O)C1=C(C)NC(=NC1c2cccs2)SC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D18 compound treatment 0.271 0.0325 0.34 0.398 0.142 1.7 1.4466 0.8323 3179122 Maybridge4_000788 CCOC(=O)c1cnc(SCc2c(C)cc(C)cc2C)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D19 compound treatment 0.306 0.0675 0.71 0.369 0.113 1.36 1.4612 0.9542 1515946 Maybridge4_000789 Fc1ccc(cc1)C(=O)ON(C2C3CC4CC(C3)CC2C4)C(=O)c5ccc(F)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D20 compound treatment 0.204 -0.0345 -0.36 0.25 -0.00556 -0.07 -0.303 -0.8233 1700551 Maybridge4_000790 COC(=O)CNS(=O)(=O)c1ccsc1C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D21 compound treatment 0.391 0.153 1.6 0.268 0.0124 0.15 1.238 0.7695 1564868 Maybridge4_000791 Clc1cc(Cl)cc(c1)c2nnc(o2)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D22 compound treatment 0.257 0.0185 0.19 0.283 0.0274 0.33 0.3697 0.9689 3179123 Maybridge4_000792 COc1cc2ncnc(NCCCn3ccnc3)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D23 mock treatment 0.202 -0.0365 -0.38 0.241 -0.0146 -0.17 -0.394 -0.9364 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 D24 mock treatment 0.215 -0.0235 -0.25 0.241 -0.0146 -0.17 -0.2975 -0.9856 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E01 compound treatment 0.941 0.703 7.38 0.972 0.716 8.57 11.2785 0.9972 3062517 Maybridge4_000793 CCc1nc2ccccc2nc1CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E02 compound treatment 0.348 0.11 1.15 0.394 0.138 1.66 1.9846 0.9841 3179124 Maybridge4_000794 Cc1nc(S)c(C#N)c(C)c1Cc2ccc(Cl)cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E03 compound treatment 0.752 0.514 5.39 0.807 0.551 6.6 8.479 0.995 3062519 Maybridge4_000795 Fc1cccc(CSCc2c(F)cccc2Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E04 compound treatment 0.261 0.0225 0.24 0.341 0.0854 1.02 0.8901 0.8484 3179125 Maybridge4_000796 CN(C)/C=N/S(=O)(=O)c1c(C)noc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E05 compound treatment 0.189 -0.0495 -0.52 0.209 -0.0466 -0.56 -0.7613 -0.9994 3062520 Maybridge4_000797 CCOc1ccccc1CCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E06 compound treatment 0.323 0.0845 0.89 0.377 0.121 1.45 1.6552 0.9721 3179126 Maybridge4_000798 COc1ccc(NS(=O)(=O)c2ccc(Oc3c(C#N)cccc3C#N)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E07 compound treatment 0.24 0.00153 0.02 0.265 0.00944 0.11 0.0912 0.7997 3062522 Maybridge4_000799 Clc1ccc(cc1)S(=O)(=O)NC(=N)N2CCSCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E08 compound treatment 0.285 0.0465 0.49 0.27 0.0144 0.17 0.4677 0.9023 3179127 Maybridge4_000800 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ccnc(NC(=O)Nc3ccccc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E09 compound treatment 0.862 0.624 6.55 0.875 0.619 7.41 9.8712 0.9981 1521882 Maybridge4_000801 Clc1ccccc1C(=O)NC(=O)OCc2cccc(Oc3ccccc3)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E10 compound treatment 0.318 0.0795 0.84 0.324 0.0684 0.82 1.1696 1.0 3179128 Maybridge4_000802 O=C(c1ccccc1)n2cc3SCc4ccccc4-c3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E11 compound treatment 0.392 0.154 1.61 0.359 0.103 1.24 2.0153 0.9915 1615025 Maybridge4_000803 Fc1ccc(cc1)C(=O)CCC(=O)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E12 compound treatment 0.311 0.0725 0.76 0.341 0.0854 1.02 1.2615 0.9895 1276755 Maybridge4_000804 CN(n1cnc2ccsc2c1=O)S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E13 compound treatment 0.315 0.0765 0.8 0.331 0.0754 0.9 1.2066 0.9983 1254744 Maybridge4_000805 Clc1ccc(NC(=O)NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E14 compound treatment 0.33 0.0915 0.96 0.355 0.0994 1.19 1.521 0.9944 1341148 Maybridge4_000806 O=C(Nc1ccccc1)n2nnc(n2)C3CN(Cc4ccccc4)CN(Cc5ccccc5)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E15 compound treatment 0.185 -0.0535 -0.56 0.234 -0.0216 -0.26 -0.5795 -0.9377 1687071 Maybridge4_000807 CNC(=O)NCc1c(cccc1N(C)C)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E16 compound treatment 0.252 0.0135 0.14 0.27 0.0144 0.17 0.2226 0.9953 3179129 Maybridge4_000808 NC(=O)/C(=C/1\SC=C(N1Cc2ccccc2)c3ccccc3)/C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E17 compound treatment 0.112 -0.126 -1.33 0.127 -0.129 -1.54 -2.0269 -0.9973 3062558 Maybridge4_000809 CCc1cnc(/N=C/N(C)C)nc1c2c(F)cccc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E18 compound treatment 0.228 -0.0105 -0.11 0.247 -0.00856 -0.1 -0.1502 -0.9994 3179130 Maybridge4_000810 Cc1nc(c(s1)c2ccccc2)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E19 compound treatment 0.207 -0.0315 -0.33 0.243 -0.0126 -0.15 -0.34 -0.9364 3062560 Maybridge4_000811 COC(CNC(=S)Nc1ccccc1Cl)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E20 compound treatment 0.564 0.326 3.42 0.66 0.404 4.84 5.8392 0.9855 1542710 Maybridge4_000812 COc1ccc(CCn2nnc3ccccc3c2=O)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E21 compound treatment 0.223 -0.0155 -0.16 0.241 -0.0146 -0.17 -0.2381 -0.9994 1303354 Maybridge4_000813 CC(C)NC(=O)NC1CCCCNC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E22 compound treatment 0.436 0.198 2.07 0.477 0.221 2.65 3.3404 0.9927 3062562 Maybridge4_000814 O=C(N1C(Oc2ccccc12)c3ccc4OCOc4c3)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E23 mock treatment 0.195 -0.0435 -0.46 0.232 -0.0236 -0.28 -0.5222 -0.9732 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 E24 mock treatment 0.249 0.0105 0.11 0.256 4.37E-4 0.01 0.0819 0.7397 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F01 compound treatment 0.175 -0.0635 -0.67 0.163 -0.0926 -1.11 -1.2544 -0.9705 3179131 Maybridge4_000815 CN1CNC(=NC1)SCc2c(C)c(C)c(C)c(C)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F02 compound treatment 0.208 -0.0305 -0.32 0.235 -0.0206 -0.25 -0.4002 -0.9916 3062563 Maybridge4_000816 Cn1ncc(C(=O)O)c1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F03 compound treatment 0.115 -0.123 -1.3 0.154 -0.102 -1.22 -1.7762 -0.9995 3179132 Maybridge4_000817 C(SC1=NCCCN1C2CCCCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F04 compound treatment 0.302 0.0635 0.67 0.337 0.0814 0.97 1.1608 0.9829 3062565 Maybridge4_000818 Cc1cc(SC(=O)N/C=C/c2ccco2)c(C)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F05 compound treatment 0.368 0.13 1.36 0.402 0.146 1.75 2.2008 0.9922 1151481 Maybridge4_000819 CC(=O)Nc1ccc(cc1)C2Nc3cc(C)ccc3O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F06 compound treatment 0.209 -0.0295 -0.31 0.24 -0.0156 -0.19 -0.3505 -0.9704 1566379 Maybridge4_000820 O=C1CCC(=O)N1c2sc3CCCCc3c2C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F07 compound treatment 0.404 0.166 1.74 0.476 0.22 2.64 3.0943 0.9795 1625831 Maybridge4_000821 CC(C)(C)n1c(n[nH]c1=S)c2ccncc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F08 compound treatment 0.223 -0.0155 -0.16 0.219 -0.0366 -0.44 -0.4242 -0.909 3179133 Maybridge4_000822 CCCc1c(cnn1c2ccccc2)C(=O)Sc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F09 compound treatment 0.304 0.0655 0.69 0.341 0.0854 1.02 1.2095 0.9815 1730421 Maybridge4_000823 CC(NC(=O)c1ccccc1C(=O)NC(C)c2ccc3OCCOc3c2)c4ccc5OCCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F10 compound treatment 0.077 -0.161 -1.7 0.12 -0.136 -1.62 -2.346 -0.9998 3062566 Maybridge4_000824 COC(=O)c1sccc1NN2C(=O)c3ccccc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F11 compound treatment 0.486 0.248 2.6 0.465 0.209 2.51 3.6102 0.9998 1672433 Maybridge4_000825 Cc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)C(C#N)c3ccc4OCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F12 compound treatment 0.244 0.00553 0.06 0.229 -0.0266 -0.32 -0.1836 -0.5684 3179134 Maybridge4_000826 COC(=O)c1cnc(NN2C(=O)CCC2=O)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F13 compound treatment 0.069 -0.169 -1.78 0.082 -0.174 -2.08 -2.7269 -0.9971 3179135 Maybridge4_000827 FC(F)(F)c1cccc(NC(=S)N(CCC#N)C2CCCCC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F14 compound treatment 0.63 0.392 4.11 0.573 0.317 3.8 5.5933 0.9992 3062567 Maybridge4_000828 COC(=O)c1c(C)sc2c(cc(=O)[nH]c12)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F15 compound treatment 0.275 0.0365 0.38 0.322 0.0664 0.79 0.8334 0.9442 3062568 Maybridge4_000829 Clc1cccc(Cl)c1C(=O)N=C2NCCN2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F16 compound treatment 1.002 0.764 8.02 1.021 0.765 9.16 12.1461 0.9978 1243939 Maybridge4_000830 COC(=O)c1ccsc1NC(=O)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F17 compound treatment 0.956 0.718 7.54 0.977 0.721 8.63 11.4322 0.9977 3062570 Maybridge4_000831 S=C1CCc2ccccc2N1Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F18 compound treatment 0.173 -0.0655 -0.69 0.263 0.00744 0.09 -0.4233 -0.6105 3179136 Maybridge4_000832 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccc(Cl)cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F19 compound treatment 0.286 0.0475 0.5 0.305 0.0494 0.59 0.7712 0.9964 3179137 Maybridge4_000833 FC(F)(F)Oc1ccc(NC(=O)N/C(=C(\N=C/c2ccc(Cl)cc2)/C#N)/C#N)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F20 compound treatment 0.613 0.375 3.93 0.686 0.43 5.15 6.423 0.9912 1627087 Maybridge4_000834 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F21 compound treatment 0.325 0.0865 0.91 0.328 0.0724 0.87 1.2555 0.9997 3062571 Maybridge4_000835 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnc(o2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F22 compound treatment 0.246 0.00753 0.08 0.237 -0.0186 -0.22 -0.1011 -0.4289 3179138 Maybridge4_000836 COc1cc2ncnc(NCCCN3CCOCC3)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F23 mock treatment 0.244 0.00553 0.06 0.28 0.0244 0.29 0.2478 0.8313 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 F24 mock treatment 0.233 -0.00547 -0.06 0.261 0.00544 0.07 0.0054 0.0621 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G01 compound treatment 0.236 -0.00247 -0.03 0.262 0.00644 0.08 0.0361 0.4446 3179214 Maybridge4_000837 CC(C)(C)C(=N)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G02 compound treatment 0.202 -0.0365 -0.38 0.254 -0.00156 -0.02 -0.2841 -0.7407 1694181 Maybridge4_000838 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NC3CCSC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G03 compound treatment 0.332 0.0935 0.98 0.348 0.0924 1.11 1.4766 0.9983 3179215 Maybridge4_000839 Cc1onc(c1CSc2nncn2C(C)(C)C)c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G04 compound treatment 0.229 -0.00947 -0.1 0.243 -0.0126 -0.15 -0.1766 -0.9799 3062572 Maybridge4_000840 FC(F)(F)c1cccc(c1)C(C#N)c2cccc(c2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G05 compound treatment 0.21 -0.0285 -0.3 0.263 0.00744 0.09 -0.1485 -0.476 3179216 Maybridge4_000841 CN(C)/C=C/1\CC(=C(O)C1=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G06 compound treatment 0.451 0.213 2.23 0.53 0.274 3.28 3.9001 0.9823 3062573 Maybridge4_000842 CSc1cc(nn1S(=O)(=O)c2ccc(F)cc2F)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G07 compound treatment 0.223 -0.0155 -0.16 0.25 -0.00556 -0.07 -0.1619 -0.9224 3179217 Maybridge4_000843 Fc1ccc(NC(=O)NC(=O)Cc2c(F)cccc2Cl)cc1Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G08 compound treatment 0.854 0.616 6.46 0.838 0.582 6.97 9.4987 0.9993 1112281 Maybridge4_000844 Clc1ccc(cc1)S(=O)(=O)NCc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G09 compound treatment 0.243 0.00453 0.05 0.285 0.0294 0.35 0.2827 0.7954 3179218 Maybridge4_000845 CC(C)(C)c1nc(NC(=N)N)sc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G10 compound treatment 0.239 5.31E-4 0.01 0.248 -0.00756 -0.09 -0.06 -0.6622 1361037 Maybridge4_000846 N#CC1CN(Cc2cccs2)CN(Cc3cccs3)C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G11 compound treatment 0.517 0.279 2.93 0.533 0.277 3.32 4.4157 0.998 3062574 Maybridge4_000847 CSCC(CSC)OC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G12 compound treatment 0.382 0.144 1.51 0.41 0.154 1.85 2.3725 0.9949 3179219 Maybridge4_000848 CN(n1cnc2ccsc2c1=O)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G13 compound treatment 0.113 -0.125 -1.32 0.138 -0.118 -1.41 -1.9264 -0.9995 3179220 Maybridge4_000849 CN(C)/C=N/C1=C(C(=O)c2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G14 compound treatment 0.843 0.605 6.35 0.817 0.561 6.72 9.2394 0.9996 3062606 Maybridge4_000850 CC1N(CCc2sccc12)C(=O)c3ccc(cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G15 compound treatment 0.367 0.129 1.35 0.388 0.132 1.58 2.075 0.9968 1282646 Maybridge4_000851 CN(C(=O)Nc1ccc(Cl)cc1)n2cnc3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G16 compound treatment 0.31 0.0715 0.75 0.323 0.0674 0.81 1.1018 0.9994 3179221 Maybridge4_000852 CCOC(=O)/C(=C/1\SC=C(N1c2c(C)cccc2C)c3ccccc3)/C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G17 compound treatment 0.726 0.488 5.12 0.702 0.446 5.34 7.3976 0.9998 3062608 Maybridge4_000853 CNC(=O)n1cc(C)c(n1)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G18 compound treatment 1.359 1.12 11.77 1.373 1.12 13.37 17.7753 0.998 1645665 Maybridge4_000854 Cc1ccc(cc1C)c2nn(CCO)c(=O)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G19 compound treatment 0.248 0.00953 0.1 0.294 0.0384 0.46 0.396 0.8413 1361478 Maybridge4_000855 Cc1nn(C)c(C)c1Nc2nc(N)n[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G20 compound treatment 0.236 -0.00247 -0.03 0.249 -0.00656 -0.08 -0.0739 -0.8932 3179222 Maybridge4_000856 CC1CN(CC(C)O1)C(=N)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G21 compound treatment 0.181 -0.0575 -0.6 0.258 0.00244 0.03 -0.4062 -0.6722 3062610 Maybridge4_000857 Clc1ccc(SS(=O)(=O)CS(=O)(=O)Sc2ccc(Cl)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G22 compound treatment 0.111 -0.127 -1.34 0.106 -0.15 -1.79 -2.212 -0.9898 3179223 Maybridge4_000858 Clc1ccc(cc1Cl)C2Nc3ccccc3O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G23 mock treatment 0.244 0.00553 0.06 0.246 -0.00956 -0.11 -0.0398 -0.3104 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 G24 mock treatment 0.209 -0.0295 -0.31 0.261 0.00544 0.07 -0.1728 -0.5465 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H01 compound treatment 0.135 -0.103 -1.09 0.133 -0.123 -1.47 -1.8053 -0.9891 3062611 Maybridge4_000859 CCN1CNC(=NC1)SCc2c(C)c(C)c(C)c(C)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H02 compound treatment 0.596 0.358 3.76 0.693 0.437 5.23 6.356 0.9867 3179224 Maybridge4_000860 CCOC(=O)c1sc(SC)nc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H03 compound treatment 0.284 0.0455 0.48 0.308 0.0524 0.63 0.7818 0.991 1702677 Maybridge4_000861 COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H04 compound treatment 0.245 0.00653 0.07 0.25 -0.00556 -0.07 0.0014 0.0151 1349117 Maybridge4_000862 CCOC(=O)c1cnn(C)c1NS(=O)(=O)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H05 compound treatment 0.181 -0.0575 -0.6 0.172 -0.0836 -1.0 -1.1337 -0.9708 3179225 Maybridge4_000863 COc1ccc(C/N=C/c2ccc(NC(=O)C)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H06 compound treatment 0.109 -0.129 -1.36 0.163 -0.0926 -1.11 -1.7446 -0.9948 3062612 Maybridge4_000864 FC(F)(F)c1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C=CC3=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H07 compound treatment 0.084 -0.154 -1.62 0.104 -0.152 -1.81 -2.4294 -0.9985 1216743 Maybridge4_000865 Clc1ccc(cc1)C(=C)NCc2ccco2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H08 compound treatment 0.783 0.545 5.72 0.811 0.555 6.65 8.743 0.9972 3062613 Maybridge4_000866 CSc1cc(nn1S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H09 compound treatment 0.278 0.0395 0.42 0.318 0.0624 0.75 0.8218 0.9616 1649762 Maybridge4_000867 CC1C(OCCN1C(=O)CCN2C(=O)c3ccccc3C2=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H10 compound treatment 0.043 -0.195 -2.05 0.043 -0.213 -2.54 -3.25 -0.9944 3062614 Maybridge4_000868 COC(=O)c1scc(C)c1NN2C(=O)C=C(C)C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H11 compound treatment 0.412 0.174 1.82 0.391 0.135 1.62 2.4346 0.9983 1683075 Maybridge4_000869 CC1CC(CC(C)(C)C1)N(CCC#N)S(=O)(=O)c2ccc(Br)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H12 compound treatment 0.224 -0.0145 -0.15 0.202 -0.0536 -0.64 -0.5606 -0.8512 3062615 Maybridge4_000870 COC(=O)c1sc2cc(sc2c1C)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H13 compound treatment 0.632 0.394 4.13 0.663 0.407 4.87 6.3695 0.9966 3179226 Maybridge4_000871 Cc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H14 compound treatment 1.024 0.786 8.25 1.017 0.761 9.11 12.2756 0.9988 3062616 Maybridge4_000872 COC(=O)c1cc2c(nn(C)c2s1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H15 compound treatment 0.947 0.709 7.44 1.018 0.762 9.12 11.7122 0.9949 3179227 Maybridge4_000873 COc1ccc(cc1)c2c(N)nc(nc2SC)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H16 compound treatment 0.313 0.0745 0.78 0.269 0.0134 0.16 0.6672 0.8349 3179228 Maybridge4_000874 CC(=O)N(c1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H17 compound treatment 0.355 0.117 1.22 0.355 0.0994 1.19 1.7067 0.9999 1612694 Maybridge4_000875 Nc1nc2Oc3ccc(Br)cc3C4C(C#N)C(O)(Nc(c1C#N)c42)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H18 compound treatment 0.569 0.331 3.47 0.601 0.345 4.13 5.3771 0.9962 1678485 Maybridge4_000876 Cn1nccc1NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H19 compound treatment 0.072 -0.166 -1.75 0.074 -0.182 -2.17 -2.7723 -0.9942 3062617 Maybridge4_000877 CC(C)/N=C/c1ccc(cc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H20 compound treatment 0.189 -0.0495 -0.52 0.248 -0.00756 -0.09 -0.4314 -0.8179 3179229 Maybridge4_000878 Cn1nccc1NC(=O)/C=C/C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H21 compound treatment 0.258 0.0195 0.21 0.237 -0.0186 -0.22 -0.012 -0.0397 3062618 Maybridge4_000879 Cn1ccc(NC(=O)NC(=O)c2c(F)cccc2F)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H22 compound treatment 0.305 0.0665 0.7 0.33 0.0744 0.89 1.1238 0.9928 1656689 Maybridge4_000880 OCCNc1ncnc2sc3CCCCc3c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H23 mock treatment 0.269 0.0305 0.32 0.244 -0.0116 -0.14 0.1289 0.3692 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 H24 mock treatment 0.233 -0.00547 -0.06 0.252 -0.00356 -0.04 -0.0708 -0.9892 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I01 compound treatment 0.222 -0.0165 -0.17 0.227 -0.0286 -0.34 -0.3639 -0.9502 3062619 Maybridge4_000881 Cc1n[nH]c(C)c1Cc2c(F)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I02 compound treatment 0.542 0.304 3.19 0.563 0.307 3.68 4.8551 0.9975 1705532 Maybridge4_000882 O=C(Nc1ccccc1)N2CCCC2c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I03 compound treatment 0.173 -0.0655 -0.69 0.196 -0.0596 -0.71 -0.9901 -0.9998 3062620 Maybridge4_000883 Nc1ccccc1C2C=NNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I04 compound treatment 0.454 0.216 2.26 0.555 0.299 3.58 4.1339 0.9755 3179230 Maybridge4_000884 Fc1c(COC(=O)c2ccccc2)cccc1COC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I05 compound treatment 0.32 0.0815 0.86 0.445 0.189 2.27 2.2082 0.9114 3062621 Maybridge4_000885 CSC(=S)N(C)/N=C/c1cc(Cl)cc(Cl)c1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I06 compound treatment 0.287 0.0485 0.51 0.357 0.101 1.21 1.2186 0.9257 3179231 Maybridge4_000886 Cc1nc(NC(=N)NC(=O)Nc2ccc(Cl)cc2)sc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I07 compound treatment 0.246 0.00753 0.08 0.255 -5.63E-4 -0.01 0.0512 0.6446 3062622 Maybridge4_000887 Fc1ccccc1C(=O)Oc2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I08 compound treatment 0.292 0.0535 0.56 0.331 0.0754 0.9 1.0358 0.9741 3179232 Maybridge4_000888 Clc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I09 compound treatment 0.6 0.362 3.8 0.647 0.391 4.68 5.9965 0.9946 1166421 Maybridge4_000889 Fc1cc(CSc2nc3ccccc3s2)c4OCOCc4c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I10 compound treatment 0.311 0.0725 0.76 0.312 0.0564 0.68 1.0161 0.9982 1473503 Maybridge4_000890 OC(=O)C1(CN(CCc2ccc(Cl)cc2)CN(CCc3ccc(Cl)cc3)C1)C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I11 compound treatment 0.215 -0.0235 -0.25 0.258 0.00244 0.03 -0.1537 -0.6191 3179233 Maybridge4_000891 FC(F)(F)c1cc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I12 compound treatment 1.279 1.04 10.93 1.374 1.12 13.38 17.1897 0.9949 3062667 Maybridge4_000892 COc1cccc(OC)c1SC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I13 compound treatment 0.28 0.0415 0.44 0.321 0.0654 0.78 0.862 0.9619 3062668 Maybridge4_000893 C/C(=N\O)/Cc1ncn(n1)c2cc(C)on2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I14 compound treatment 0.187 -0.0515 -0.54 0.249 -0.00656 -0.08 -0.4378 -0.8014 3179234 Maybridge4_000894 Clc1ccc(/C=N/N2CCOCC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I15 compound treatment 0.244 0.00553 0.06 0.291 0.0354 0.42 0.3409 0.7965 3062670 Maybridge4_000895 OCCCc1cc(n[nH]1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I16 compound treatment 0.195 -0.0435 -0.46 0.247 -0.00856 -0.1 -0.3953 -0.8448 3179329 Maybridge4_000896 O=C(CC#N)Nc1ccncc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I17 compound treatment 0.041 -0.197 -2.07 0.043 -0.213 -2.54 -3.2648 -0.9949 3062671 Maybridge4_000897 CN(C)/C=C/C(=O)c1nnn(c1C)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I18 compound treatment 1.468 1.23 12.91 1.461 1.21 14.42 19.3293 0.9985 1670735 Maybridge4_000898 OCCn1nc(c2ccc(F)cc2)c3ccccc3c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I19 compound treatment 0.205 -0.0335 -0.35 0.261 0.00544 0.07 -0.2026 -0.5666 3179330 Maybridge4_000899 Cc1onc(c1NC(=O)NC2CCSC2)c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I20 compound treatment 0.231 -0.00747 -0.08 0.296 0.0404 0.48 0.2866 0.5848 3062672 Maybridge4_000900 CSC1=NNC(N1)c2ccc(cc2)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I21 compound treatment 0.211 -0.0275 -0.29 0.232 -0.0236 -0.28 -0.4033 -0.9999 3062673 Maybridge4_000901 CSc1nc(/N=C/N(C)C)nn1CCC#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I22 compound treatment 0.469 0.231 2.42 0.476 0.22 2.64 3.577 0.9991 1639939 Maybridge4_000902 Cc1ccc(cc1)S(=O)(=O)N2C(Oc3ccccc23)c4ccc(Cl)c(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I23 mock treatment 0.267 0.0285 0.3 0.268 0.0124 0.15 0.3171 0.9478 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 I24 mock treatment 0.269 0.0305 0.32 0.276 0.0204 0.24 0.3996 0.991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J01 compound treatment 0.167 -0.0715 -0.75 0.192 -0.0636 -0.76 -1.0685 -1.0 3062674 Maybridge4_000903 CCN1CNC(=NC1)SCc2cccc(C#N)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J02 compound treatment 1.253 1.01 10.66 1.268 1.01 12.11 16.0998 0.998 3179331 Maybridge4_000904 CCCc1c(cnn1C)C(=O)Nc2cc(F)ccc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J03 compound treatment 0.096 -0.142 -1.5 0.115 -0.141 -1.68 -2.2472 -0.9983 3179332 Maybridge4_000905 CC(O)CN1CNC(=NC1)SCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J04 compound treatment 0.26 0.0215 0.23 0.286 0.0304 0.36 0.4174 0.9737 3062676 Maybridge4_000906 COC(=O)c1sc(cc1NC(=O)C(F)(F)F)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J05 compound treatment 0.149 -0.0895 -0.94 0.193 -0.0626 -0.75 -1.1937 -0.9937 3179333 Maybridge4_000907 OCCN1CNC(=NC1)SCc2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J06 compound treatment 0.709 0.471 4.94 0.652 0.396 4.74 6.8483 0.9998 3062677 Maybridge4_000908 COC(=O)c1scc(C)c1S(=O)(=O)Nc2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J07 compound treatment 0.266 0.0275 0.29 0.258 0.00244 0.03 0.2251 0.7745 1718232 Maybridge4_000909 O=c1n2CCN(Cc3ccccc3)c2nc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J08 compound treatment 0.243 0.00453 0.05 0.298 0.0424 0.51 0.3927 0.77 3062678 Maybridge4_000910 CCOC(=O)c1c[nH]c(=S)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J09 compound treatment 0.04 -0.198 -2.08 0.041 -0.215 -2.57 -3.2892 -0.9947 3179334 Maybridge4_000911 Cc1cc2ccccc2c(/N=C/c3cc(Br)cc(Br)c3O)c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J10 compound treatment 0.242 0.00353 0.04 0.288 0.0324 0.39 0.3007 0.7712 1179240 Maybridge4_000912 COc1ccc(cc1)c2cc(N)nc(N)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J11 compound treatment 0.269 0.0305 0.32 0.305 0.0494 0.59 0.645 0.9586 1730849 Maybridge4_000913 Cc1ccc(cc1)S(=O)(=O)N(CCC#N)CC2CCCO2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J12 compound treatment 1.18 0.942 9.89 1.141 0.885 10.59 14.4832 0.9994 3062679 Maybridge4_000914 COC(=O)c1cnc(Nc2ccccc2)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J13 compound treatment 0.469 0.231 2.42 0.295 0.0394 0.47 2.0457 0.8293 3179335 Maybridge4_000915 CC(C)c1ccc(NC(=S)Nc2cccc(c2)C(F)(F)F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J14 compound treatment 0.111 -0.127 -1.34 0.13 -0.126 -1.5 -2.0089 -0.9983 1398467 Maybridge4_000916 COC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)c3ncnc4c(C)csc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J15 compound treatment 0.2 -0.0385 -0.4 0.268 0.0124 0.15 -0.1805 -0.4191 3062680 Maybridge4_000917 COC(=O)c1ccc(/N=C/N(C)C)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J16 compound treatment 0.954 0.716 7.51 1.055 0.799 9.56 12.0773 0.9929 1273229 Maybridge4_000918 COC(=O)c1ccsc1N2C(=O)c3ccccc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J17 compound treatment 0.187 -0.0515 -0.54 0.205 -0.0506 -0.6 -0.81 -0.9984 1150677 Maybridge4_000919 COc1ccc2Oc3nc(N)c(C#N)c(N)c3C(C(C#N)C#N)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J18 compound treatment 0.547 0.309 3.24 0.627 0.371 4.44 5.4337 0.988 3179336 Maybridge4_000920 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccccc3OC)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J19 compound treatment 0.115 -0.123 -1.3 0.108 -0.148 -1.77 -2.1653 -0.9885 3062681 Maybridge4_000921 C1CC1/N=C/c2ccc(cc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J20 compound treatment 0.273 0.0345 0.36 0.356 0.1 1.2 1.1062 0.8813 1209715 Maybridge4_000922 COc1cc(C(=O)NN)c(cc1OC)n2c(C)ccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J21 compound treatment 0.204 -0.0345 -0.36 0.229 -0.0266 -0.32 -0.4807 -0.9979 3179337 Maybridge4_000923 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccsc2C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J22 compound treatment 0.234 -0.00447 -0.05 0.246 -0.00956 -0.11 -0.1141 -0.9226 3062682 Maybridge4_000924 Cn1nccc1NC(=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J23 mock treatment 0.272 0.0335 0.35 0.331 0.0754 0.9 0.8872 0.9158 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 J24 mock treatment 0.241 0.00253 0.03 0.255 -5.63E-4 -0.01 0.014 0.512 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K01 compound treatment 0.187 -0.0515 -0.54 0.215 -0.0406 -0.49 -0.7254 -0.9986 3179338 Maybridge4_000925 CN(C)/C=N/S(=O)(=O)c1c(C)c(C)c(C)c(C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K02 compound treatment 0.448 0.21 2.2 0.498 0.242 2.9 3.6071 0.9907 1131158 Maybridge4_000926 O=S(=O)(N1CCCC1c2cccs2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K03 compound treatment 0.233 -0.00547 -0.06 0.24 -0.0156 -0.19 -0.1723 -0.8841 1673268 Maybridge4_000927 COc1ccc(CCn2cnn3c(=O)c4ccccc4nc3c2=O)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K04 compound treatment 0.655 0.417 4.37 0.79 0.534 6.39 7.6148 0.9829 3062684 Maybridge4_000928 Clc1ccc(Sc2c(C#N)cccc2C#N)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K05 compound treatment 0.217 -0.0215 -0.23 0.328 0.0724 0.87 0.4534 0.5063 3179339 Maybridge4_000929 Cc1onc(c1C(=O)NC(=N)N2CCCC2)c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K06 compound treatment 0.13 -0.108 -1.14 0.13 -0.126 -1.5 -1.8678 -0.9907 3062686 Maybridge4_000930 NC(=O)N/C(=N\O)/CSc1ccc(Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K07 compound treatment 0.31 0.0715 0.75 0.352 0.0964 1.15 1.3471 0.9784 3179340 Maybridge4_000931 Clc1ccc(SCC(=N)NS(=O)(=O)c2ccc(Cl)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K08 compound treatment 0.114 -0.124 -1.31 0.138 -0.118 -1.41 -1.919 -0.9993 3179341 Maybridge4_000932 CCN(S(=O)(=O)c1ccc(F)cc1)S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K09 compound treatment 0.286 0.0475 0.5 0.311 0.0554 0.66 0.822 0.9902 3062687 Maybridge4_000933 CS(=O)(=O)Cc1cc(F)cc2COCOc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K10 compound treatment 1.005 0.767 8.05 0.987 0.731 8.75 11.8807 0.9991 1659719 Maybridge4_000934 Fc1cccc(Cl)c1CSC2=CC(=O)CC(C2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K11 compound treatment 0.663 0.425 4.46 0.71 0.454 5.44 6.9974 0.9951 3179342 Maybridge4_000935 Cc1c(C)c(C)c(C#CCOC2CCCCO2)c(C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K12 compound treatment 0.192 -0.0465 -0.49 0.273 0.0174 0.21 -0.1976 -0.3722 3179343 Maybridge4_000936 COc1cccc(OC)c1C(=O)c2cc[n+](C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K13 compound treatment 0.723 0.485 5.09 0.732 0.476 5.7 7.6291 0.9984 3062688 Maybridge4_000937 N#Cc1c(oc(c1c2ccc(C#N)cc2)n3cccc3)c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K14 compound treatment 0.088 -0.15 -1.58 0.094 -0.162 -1.93 -2.4843 -0.995 3179344 Maybridge4_000938 Clc1ccc(/C=N/N2CCCCC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K15 compound treatment 0.127 -0.111 -1.17 0.174 -0.0816 -0.98 -1.5179 -0.9959 3062689 Maybridge4_000939 CN(C)/C=N/c1c(cnn1C)c2nc(cs2)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K16 compound treatment 0.892 0.654 6.86 0.977 0.721 8.63 10.9569 0.9936 1505900 Maybridge4_000940 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K17 compound treatment 0.573 0.335 3.51 0.614 0.358 4.29 5.5168 0.9951 3179345 Maybridge4_000941 CN(C1CC2CC1C=C2)C(=O)Nc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K18 compound treatment 0.158 -0.0805 -0.85 0.271 0.0154 0.18 -0.467 -0.5398 1333053 Maybridge4_000942 N1C(Nc2ccccc12)c3c[nH]c4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K19 compound treatment 0.165 -0.0735 -0.77 0.199 -0.0566 -0.68 -1.0241 -0.9979 3062581 Maybridge4_000943 CC(C)(C)c1cc2N=CN3CCN=C3n2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K20 compound treatment 0.339 0.101 1.06 0.433 0.177 2.12 2.2477 0.948 3179346 Maybridge4_000944 CN(CCC#N)c1ccc(/C=C/2\CC/C(=C\c3ccc(cc3)N(C)CCC#N)/C2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K21 compound treatment 0.854 0.616 6.46 0.864 0.608 7.28 9.7187 0.9982 3062583 Maybridge4_000945 CC1SCC(CS1)NC(=O)Nc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K22 compound treatment 0.086 -0.152 -1.6 0.112 -0.144 -1.72 -2.3469 -0.9994 3179347 Maybridge4_000946 COc1ccc(cc1)C2Nc3ccccc3O2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K23 mock treatment 0.217 -0.0215 -0.23 0.208 -0.0476 -0.57 -0.5618 -0.9179 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 K24 mock treatment 0.247 0.00853 0.09 0.255 -5.63E-4 -0.01 0.0586 0.6522 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L01 compound treatment 0.123 -0.115 -1.21 0.14 -0.116 -1.38 -1.8352 -0.9979 3062584 Maybridge4_000947 CN1CNC(=NC1)SCc2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L02 compound treatment 0.38 0.142 1.49 0.441 0.185 2.22 2.6199 0.981 3179348 Maybridge4_000948 Cn1cc(NC(=O)Nc2ccc(cc2)C(F)(F)F)c(n1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L03 compound treatment 0.112 -0.126 -1.33 0.14 -0.116 -1.38 -1.9169 -0.9998 3062585 Maybridge4_000949 CN(C)/N=C(\N)/c1ccc(Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L04 compound treatment 0.35 0.112 1.17 0.356 0.1 1.2 1.678 0.9999 3179349 Maybridge4_000950 NC(=O)c1sc(cc1NC(=O)c2cccs2)c3ccsc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L05 compound treatment 0.112 -0.126 -1.33 0.149 -0.107 -1.27 -1.8408 -0.9998 3062586 Maybridge4_000951 CSC1=NCN(CCCO)CN1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L06 compound treatment 0.209 -0.0295 -0.31 0.29 0.0344 0.41 0.0725 0.1407 3179350 Maybridge4_000952 FC(F)(F)c1cc(=O)oc2cc(ccc12)N3C(=O)c4ccccc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L07 compound treatment 0.278 0.0395 0.42 0.328 0.0724 0.87 0.9064 0.9432 3062588 Maybridge4_000953 Brc1ccc(CSC2=Nc3ccccc3C(=O)NN2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L08 compound treatment 0.557 0.319 3.35 0.706 0.45 5.39 6.1763 0.9737 3179351 Maybridge4_000954 COc1ccc(CC(=O)n2nc(cc2SC)c3ccc(F)cc3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L09 compound treatment 0.826 0.588 6.17 0.749 0.493 5.9 8.5379 0.9998 3062590 Maybridge4_000955 COc1ccc(cc1OC)c2sc(/N=C/c3cccs3)c(C#N)c2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L10 compound treatment 0.512 0.274 2.87 0.609 0.353 4.23 5.0215 0.9823 3179352 Maybridge4_000956 COC(=O)c1cnc(nc1C(F)(F)F)N2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L11 compound treatment 0.149 -0.0895 -0.94 0.238 -0.0176 -0.21 -0.813 -0.8444 1310115 Maybridge4_000957 N#CCc1ccc(NC2(CCCCC2)C#N)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L12 compound treatment 0.158 -0.0805 -0.85 0.218 -0.0376 -0.45 -0.9154 -0.9563 3062591 Maybridge4_000958 FC(F)(F)c1nc(Sc2ccc(Cl)cc2)ncc1C(=O)OCc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L13 compound treatment 0.21 -0.0285 -0.3 0.309 0.0534 0.64 0.2407 0.341 3179450 Maybridge4_000959 CC1CN(CC(C)O1)C(=S)Nc2cccc(c2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L14 compound treatment 0.094 -0.144 -1.52 0.106 -0.15 -1.79 -2.3382 -0.9966 3179451 Maybridge4_000960 Cc1csc2c(ncnc12)N3CCN(CC3)C(=O)NC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L15 compound treatment 0.685 0.447 4.69 0.811 0.555 6.65 8.0152 0.9854 3062624 Maybridge4_000961 Clc1ccc2sc(Sc3ccccc3)nc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L16 compound treatment 0.208 -0.0305 -0.32 0.236 -0.0196 -0.23 -0.3918 -0.9882 3179452 Maybridge4_000962 C(N1CCC(CC1)Nc2ncnc3sccc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L17 compound treatment 0.185 -0.0535 -0.56 0.318 0.0624 0.75 0.1311 0.1403 1533957 Maybridge4_000963 CSCCC1NC(=O)NC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L18 compound treatment 0.607 0.369 3.87 0.624 0.368 4.41 5.8539 0.9979 3179453 Maybridge4_000964 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)Nc3ccc(Cl)cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L19 compound treatment 0.313 0.0745 0.78 0.386 0.13 1.56 1.657 0.9491 3062627 Maybridge4_000965 CN(C)c1ccsc1C(=O)NN 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L20 compound treatment 0.226 -0.0125 -0.13 0.279 0.0234 0.28 0.1057 0.3415 3179454 Maybridge4_000966 COc1cc2ncnc(SCC(=O)NN)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L21 compound treatment 0.133 -0.105 -1.11 0.197 -0.0586 -0.7 -1.2787 -0.9756 3062629 Maybridge4_000967 CNC(=O)c1c(C)csc1NC(=O)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L22 compound treatment 1.421 1.18 12.42 1.454 1.2 14.34 18.921 0.9974 1534695 Maybridge4_000968 CCN(CC)c1ncnc2sc3CCCCc3c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L23 mock treatment 0.22 -0.0185 -0.19 0.246 -0.00956 -0.11 -0.2181 -0.9683 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 L24 mock treatment 0.213 -0.0255 -0.27 0.237 -0.0186 -0.22 -0.3462 -0.9957 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M01 compound treatment 0.233 -0.00547 -0.06 0.231 -0.0246 -0.29 -0.2484 -0.8296 3062631 Maybridge4_000969 COc1ccc(OC)c(c1)S(=O)(=O)/N=C/N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M02 compound treatment 0.141 -0.0975 -1.02 0.221 -0.0346 -0.41 -1.0163 -0.9205 3179455 Maybridge4_000970 Cc1nn(C)c2SC(=NS(=O)(=O)c12)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M03 compound treatment 0.349 0.111 1.16 0.405 0.149 1.79 2.0851 0.9781 3062632 Maybridge4_000971 Cn1c(S)nnc1C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M04 compound treatment 0.187 -0.0515 -0.54 0.27 0.0144 0.17 -0.2601 -0.4583 3179456 Maybridge4_000972 FC(F)(F)c1ccc(CNC(=O)c2ccc(Cl)cc2Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M05 compound treatment 0.323 0.0845 0.89 0.415 0.159 1.91 1.9766 0.9394 3062633 Maybridge4_000973 CC1CN(CC(C)O1)C(=N)NS(=O)(=O)c2ccc(Cl)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M06 compound treatment 0.04 -0.198 -2.08 0.04 -0.216 -2.58 -3.2976 -0.9944 1452088 Maybridge4_000974 CN(C)c1cc(oc(=O)c1Cl)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M07 compound treatment 0.494 0.256 2.68 0.487 0.231 2.77 3.8557 0.9999 3062634 Maybridge4_000975 Fc1cccc(Cl)c1CSC(=S)N2CCSCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M08 compound treatment 0.043 -0.195 -2.05 0.045 -0.211 -2.52 -3.233 -0.9948 3179457 Maybridge4_000976 CN(C)/C=C/C(=O)C(c1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M09 compound treatment 0.268 0.0295 0.31 0.328 0.0724 0.87 0.8321 0.904 3179458 Maybridge4_000977 Cc1cc(C)n(n1)C2=NCCN2S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M10 compound treatment 0.777 0.539 5.66 0.865 0.609 7.29 9.1553 0.9921 1473043 Maybridge4_000978 CC(NS(=O)(=O)c1ccc(Oc2cccc(Cl)c2C#N)cc1)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M11 compound treatment 0.528 0.29 3.04 0.54 0.284 3.4 4.5566 0.9984 3179459 Maybridge4_000979 Cc1ccc(C)n1c2ccsc2COC(=O)Nc3c(C)onc3c4c(F)cccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M12 compound treatment 0.23 -0.00847 -0.09 0.374 0.118 1.42 0.9391 0.6614 3062636 Maybridge4_000980 CC(=O)n1nccc1c2nccnc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M13 compound treatment 0.417 0.179 1.88 0.492 0.236 2.83 3.3262 0.9801 3062637 Maybridge4_000981 Cc1cc(no1)n2cnc(n2)c3cnoc3C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M14 compound treatment 0.228 -0.0105 -0.11 0.264 0.00844 0.1 -0.0064 -0.0426 1215853 Maybridge4_000982 COC(=O)c1cccc(NC(=O)NC(C)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M15 compound treatment 0.191 -0.0475 -0.5 0.252 -0.00356 -0.04 -0.3827 -0.7648 1711378 Maybridge4_000983 Cn1ncc(NCCc2ccncc2)c(Cl)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M16 compound treatment 0.061 -0.177 -1.86 0.069 -0.187 -2.23 -2.8963 -0.996 1176335 Maybridge4_000984 CC1CCN(CC1)C(=O)C(C#N)C(=S)Nc2ccc(C)cc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M17 compound treatment 0.643 0.405 4.25 0.635 0.379 4.54 6.2143 0.9995 3179460 Maybridge4_000985 CN(C)/C=C/C(=O)c1sc(=S)n(CCc2ccc(Cl)cc2)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M18 compound treatment 0.647 0.409 4.29 0.624 0.368 4.41 6.151 0.9999 1468395 Maybridge4_000986 COc1ccc(cc1OC)c2c(C)n(C)c(C)c2c3ccc(OC)c(OC)c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M19 compound treatment 0.24 0.00153 0.02 0.278 0.0224 0.27 0.2012 0.7481 3179461 Maybridge4_000987 Cc1ccc(C)n1c2ccccc2C3C=NNC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M20 compound treatment 0.354 0.116 1.21 0.474 0.218 2.61 2.706 0.9391 1563316 Maybridge4_000988 CNc1ccccc1C(=O)NC2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M21 compound treatment 0.56 0.322 3.38 0.627 0.371 4.44 5.5303 0.9908 3179462 Maybridge4_000989 CC1SCC(CS1)NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M22 compound treatment 0.217 -0.0215 -0.23 0.316 0.0604 0.72 0.3519 0.4646 3062639 Maybridge4_000990 Cc1c(C)c(C)c(CN)c(C)c1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M23 mock treatment 0.227 -0.0115 -0.12 0.266 0.0104 0.12 0.0031 0.018 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 M24 mock treatment 0.247 0.00853 0.09 0.262 0.00644 0.08 0.1178 0.9972 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N01 compound treatment 0.258 0.0195 0.21 0.323 0.0674 0.81 0.7156 0.8595 3062690 Maybridge4_000991 CSC1=NCCCN1C(=O)c2ccccc2I 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N02 compound treatment 0.208 -0.0305 -0.32 0.295 0.0394 0.47 0.1074 0.1883 3179463 Maybridge4_000992 CCOC(=O)c1cn(CC(=O)NN)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N03 compound treatment 0.113 -0.125 -1.32 0.107 -0.149 -1.78 -2.1887 -0.9891 3062691 Maybridge4_000993 CC(C)(C)N1CNC(=NC1)SCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N04 compound treatment 0.555 0.317 3.32 0.616 0.36 4.31 5.4001 0.9917 3179464 Maybridge4_000994 NC(=O)c1sc(cc1NC(=O)/C=C/c2ccsc2)c3ccsc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N05 compound treatment 0.489 0.251 2.63 0.516 0.26 3.12 4.0639 0.9965 3179465 Maybridge4_000995 COc1cc(/C=N/N(C)C(=S)Nc2cccc(Cl)c2C)cc(OC)c1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N06 compound treatment 0.184 -0.0545 -0.57 0.256 4.37E-4 0.01 -0.4008 -0.7006 3062692 Maybridge4_000996 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)Sc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N07 compound treatment 0.438 0.2 2.1 0.383 0.127 1.52 2.56 0.9878 3179466 Maybridge4_000997 Cc1ccc2N(CCCc2c1)C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N08 compound treatment 0.14 -0.0985 -1.03 0.207 -0.0486 -0.58 -1.1421 -0.9628 1622973 Maybridge4_000998 CC1CN(CC(C)O1)c2ncnc3c(C)csc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N09 compound treatment 0.263 0.0245 0.26 0.351 0.0954 1.14 0.9896 0.8454 1148536 Maybridge4_000999 COc1cc(cc(OC)c1OC)C(=O)N2CCCN3C2c4ccccc4C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N10 compound treatment 0.207 -0.0315 -0.33 0.228 -0.0276 -0.33 -0.4669 -1.0 3062693 Maybridge4_001000 COC(=O)c1c(C)sc2cc(sc12)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N11 compound treatment 0.301 0.0625 0.66 0.354 0.0984 1.18 1.2972 0.962 1697786 Maybridge4_001001 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)C2CC(C)CC(C)(C)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N12 compound treatment 0.554 0.316 3.31 0.569 0.313 3.75 4.995 0.9981 3062695 Maybridge4_001002 CC1CN(CC(C)O1)c2ncc(C(=O)OCC3CC3)c(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N13 compound treatment 0.237 -0.00147 -0.02 0.337 0.0814 0.97 0.6781 0.6958 3179467 Maybridge4_001003 CC1CN(CC(C)O1)C(=S)Nc2c(C)cccc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N14 compound treatment 0.119 -0.119 -1.25 0.125 -0.131 -1.56 -1.9918 -0.9941 3179468 Maybridge4_001004 Cc1csc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(OC(F)(F)F)cc4)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N15 compound treatment 0.29 0.0515 0.54 0.298 0.0424 0.51 0.7417 0.9995 3062698 Maybridge4_001005 CN(C)C(=O)Oc1ccc2nnc3ccnn3c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N16 compound treatment 0.09 -0.148 -1.56 0.118 -0.138 -1.65 -2.2664 -0.9996 1412351 Maybridge4_001006 C1CCN(C1)c2ncnc3sccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N17 compound treatment 0.156 -0.0825 -0.87 0.285 0.0294 0.35 -0.3634 -0.3887 3179469 Maybridge4_001007 CC(C)CC1NC(=O)N(C)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N18 compound treatment 0.121 -0.117 -1.23 0.166 -0.0896 -1.07 -1.6301 -0.9975 1428548 Maybridge4_001008 Cn1nccc1N2C(=O)c3ccccc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N19 compound treatment 0.218 -0.0205 -0.21 0.263 0.00744 0.09 -0.0891 -0.3829 3179470 Maybridge4_001009 C/C(=N\O)/CSC(=O)c1c(C)onc1c2c(F)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N20 compound treatment 0.161 -0.0775 -0.81 0.253 -0.00256 -0.03 -0.597 -0.7332 3062700 Maybridge4_001010 CNC(=S)NCc1ccco1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N21 compound treatment 0.238 -4.69E-4 0.0 0.313 0.0574 0.69 0.4824 0.702 3179471 Maybridge4_001011 Cn1ccc(NC(=O)Nc2ccccc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N22 compound treatment 0.17 -0.0685 -0.72 0.165 -0.0906 -1.08 -1.2747 -0.9802 1103188 Maybridge4_001012 C(CNc1ncnc2sc3CCCCc3c12)CN4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N23 mock treatment 0.242 0.00353 0.04 0.284 0.0284 0.34 0.2668 0.7796 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 N24 mock treatment 0.221 -0.0175 -0.18 0.242 -0.0136 -0.16 -0.2445 -0.9981 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O01 compound treatment 0.257 0.0185 0.19 0.275 0.0194 0.23 0.3021 0.9961 3062702 Maybridge4_001013 CN(C)/C=N/S(=O)(=O)c1ccc(Cl)c(Cl)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O02 compound treatment 0.096 -0.142 -1.5 0.096 -0.16 -1.91 -2.408 -0.9927 3179472 Maybridge4_001014 Cc1nn(C)c2SC(=NS(=O)(=O)c12)SCc3c(F)cccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O03 compound treatment 0.26 0.0215 0.23 0.283 0.0274 0.33 0.392 0.9834 3062703 Maybridge4_001015 CN(C)/C=C/C(=O)c1cc(F)ccc1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O04 compound treatment 0.271 0.0325 0.34 0.317 0.0614 0.74 0.7614 0.9393 3179473 Maybridge4_001016 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)OC2CCSC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O05 compound treatment 0.256 0.0175 0.18 0.31 0.0544 0.65 0.5907 0.8728 3062704 Maybridge4_001017 CC1CN(CC(C)O1)C(=N)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O06 compound treatment 0.237 -0.00147 -0.02 0.26 0.00444 0.05 0.0266 0.4817 3179474 Maybridge4_001018 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ccn[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O07 compound treatment 1.078 0.84 8.82 1.0 0.744 8.91 12.5328 1.0 3179571 Maybridge4_001019 Fc1cccc(Cl)c1CCNC(=O)NC(=O)Cc2c(F)cccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O08 compound treatment 0.532 0.294 3.08 0.595 0.339 4.06 5.0516 0.9908 3062705 Maybridge4_001020 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)S(=O)(=O)n2cccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O09 compound treatment 0.909 0.671 7.04 1.011 0.755 9.04 11.3708 0.9924 3179572 Maybridge4_001021 CS/C(=N/S(=O)(=O)c1ccccc1)/NCCc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O10 compound treatment 0.189 -0.0495 -0.52 0.237 -0.0186 -0.22 -0.5244 -0.9281 1316388 Maybridge4_001022 Clc1ccc(cc1)S(=O)(=O)NCC2CN(Cc3ccccc3)CN(Cc4ccccc4)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O11 compound treatment 0.562 0.324 3.4 0.606 0.35 4.19 5.3675 0.9946 1687690 Maybridge4_001023 Clc1cc(Cl)cc(OC(=O)C2(CC3CC4CC(C3)C2)C4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O12 compound treatment 0.884 0.646 6.78 0.973 0.717 8.58 10.8637 0.9932 3063461 Maybridge4_001024 Cc1nc(CSCc2ccc(Cl)cc2Cl)cs1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O13 compound treatment 0.372 0.134 1.4 0.541 0.285 3.42 3.4065 0.9227 1553397 Maybridge4_001025 O=C(Nc1ccccc1)OC(CSc2ccccn2)CSc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O14 compound treatment 0.337 0.0985 1.03 0.363 0.107 1.29 1.6407 0.9942 1170892 Maybridge4_001026 COC(=O)c1cccc(NC(=O)Nc2ccccc2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O15 compound treatment 0.315 0.0765 0.8 0.351 0.0954 1.14 1.3758 0.9852 1387636 Maybridge4_001027 CN(C)c1cccc(N(C)C)c1CNS(=O)(=O)c2cc(C)c(Cl)cc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O16 compound treatment 0.368 0.13 1.36 0.425 0.169 2.03 2.3954 0.9812 1136580 Maybridge4_001028 Clc1ccccc1NC(=S)C(C#N)C(=O)N2CCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O17 compound treatment 0.343 0.105 1.1 0.391 0.135 1.62 1.9221 0.982 3063462 Maybridge4_001029 CN(C1CC2CC1C=C2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O18 compound treatment 0.847 0.609 6.39 0.938 0.682 8.16 10.2928 0.9927 1238489 Maybridge4_001030 Cc1cc2NC(=O)c3ccccc3C(=Nc2cc1C)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O19 compound treatment 0.175 -0.0635 -0.67 0.259 0.00344 0.04 -0.4423 -0.6622 3063463 Maybridge4_001031 CN(C)/C=N/c1ccccc1C2C=NNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O20 compound treatment 0.4 0.162 1.7 0.536 0.28 3.36 3.5722 0.9501 3179573 Maybridge4_001032 S=C1NCCN1Cc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O21 compound treatment 0.218 -0.0205 -0.21 0.134 -0.122 -1.45 -1.1804 -0.8029 1607454 Maybridge4_001033 CC1=C(N2CCOCC2)C(=NCCN1)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O22 compound treatment 0.238 -4.69E-4 0.0 0.311 0.0554 0.66 0.4655 0.7018 1293246 Maybridge4_001034 Cc1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O23 mock treatment 0.242 0.00353 0.04 0.279 0.0234 0.28 0.2245 0.7937 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 O24 mock treatment 0.255 0.0165 0.17 0.301 0.0454 0.54 0.5072 0.8887 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P01 compound treatment 0.228 -0.0105 -0.11 0.209 -0.0466 -0.56 -0.4717 -0.8306 1354193 Maybridge4_001035 OCCN1CNC(=S)NC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P02 compound treatment 0.245 0.00653 0.07 0.243 -0.0126 -0.15 -0.0578 -0.3497 3179574 Maybridge4_001036 FC(F)(F)c1cc(NC(=O)N/C=C/c2ccsc2)cc(c1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P03 compound treatment 0.154 -0.0845 -0.89 0.179 -0.0766 -0.92 -1.275 -0.9999 3063464 Maybridge4_001037 C(SC1=NCN(Cc2ccccc2)CN1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P04 compound treatment 0.052 -0.186 -1.96 0.053 -0.203 -2.42 -3.0985 -0.9944 3179575 Maybridge4_001038 COC(=O)c1sccc1N2C(=O)C=C(C)C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P05 compound treatment 0.553 0.315 3.3 0.395 0.139 1.67 3.5155 0.9499 3179576 Maybridge4_001039 CN(/N=C/c1ccccn1)C(=S)Nc2ccc(C)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P06 compound treatment 0.275 0.0365 0.38 0.405 0.149 1.79 1.5356 0.8397 1429512 Maybridge4_001040 CCCc1c(NC(=O)Nc2ccc(Cl)cc2Cl)cnn1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P07 compound treatment 0.112 -0.126 -1.33 0.13 -0.126 -1.5 -2.0015 -0.9981 1160255 Maybridge4_001041 N#CC1(CCCCCC1)NC(Cc2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P08 compound treatment 0.131 -0.107 -1.13 0.158 -0.0976 -1.17 -1.6235 -0.9999 1344462 Maybridge4_001042 CC(C)Nc1ncnc2c(C)csc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P09 compound treatment 0.167 -0.0715 -0.75 0.266 0.0104 0.12 -0.4425 -0.5815 3179577 Maybridge4_001043 COc1cc(cc(OC)c1OC)C2NN=C3C2N4CCC3CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P10 compound treatment 0.769 0.531 5.57 0.923 0.667 7.99 9.5866 0.9845 3063465 Maybridge4_001044 FC(F)(F)c1ccc(NC(=O)C2CCc3ccccc3O2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P11 compound treatment 0.183 -0.0555 -0.58 0.276 0.0204 0.24 -0.239 -0.3783 1463450 Maybridge4_001045 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)Cc2ccncc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P12 compound treatment 0.567 0.329 3.45 0.592 0.336 4.03 5.2861 0.9971 3179578 Maybridge4_001046 CSc1cc(nn1S(=O)(=O)c2cccc(c2)C(F)(F)F)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P13 compound treatment 0.327 0.0885 0.93 0.439 0.183 2.19 2.2094 0.9269 3063466 Maybridge4_001047 COc1cccc(NC(=S)N(CCC#N)/N=C/c2ccc3OCOc3c2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P14 compound treatment 0.16 -0.0785 -0.82 0.212 -0.0436 -0.52 -0.9513 -0.9756 1234970 Maybridge4_001048 Cc1csc2ncnc(N3CCN(CC3)C(=S)Nc4ccc(F)cc4F)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P15 compound treatment 0.196 -0.0425 -0.45 0.302 0.0464 0.56 0.0775 0.1087 1069786 Maybridge4_001049 NNC(=O)OC1(CC2CC3CC(C2)C1)C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P16 compound treatment 0.079 -0.159 -1.67 0.089 -0.167 -1.99 -2.5934 -0.9963 3179579 Maybridge4_001050 CCOC(=O)c1cnc(Sc2ccc(F)c(Cl)c2)nc1C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P17 compound treatment 0.337 0.0985 1.03 0.419 0.163 1.96 2.1144 0.9557 3063467 Maybridge4_001051 Sc1nc(ccc1C#N)c2ccc3OCCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P18 compound treatment 0.223 -0.0155 -0.16 0.299 0.0434 0.52 0.2526 0.4639 1377109 Maybridge4_001052 CCOC(=O)c1cc(=O)c2cc(Cl)ccc2o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P19 compound treatment 0.237 -0.00147 -0.02 0.307 0.0514 0.62 0.4243 0.6892 1695486 Maybridge4_001053 CC1CCCN(C1)c2ccc3nncn3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P20 compound treatment 0.108 -0.13 -1.37 0.125 -0.131 -1.56 -2.0735 -0.9979 3063468 Maybridge4_001054 Cn1ncc(Br)c1NC(=O)CSc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P21 compound treatment 0.133 -0.105 -1.11 0.138 -0.118 -1.41 -1.7779 -0.993 3179580 Maybridge4_001055 COC(=O)c1sccc1NS(=O)(=O)c2ccc(F)cc2F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P22 compound treatment 0.199 -0.0395 -0.41 0.261 0.00544 0.07 -0.2471 -0.5889 1127720 Maybridge4_001056 CCC(C)Nc1ncnc2cc(OC)c(OC)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P23 mock treatment 0.242 0.00353 0.04 0.291 0.0354 0.42 0.326 0.766 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2051 P24 mock treatment 0.212 -0.0265 -0.28 0.259 0.00344 0.04 -0.1675 -0.596 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A01 compound treatment 0.182 -0.0472 -0.5 0.179 -0.051 -0.61 -0.7824 -0.9947 1118682 Maybridge4_001057 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A02 compound treatment 0.242 0.0128 0.13 0.187 -0.043 -0.51 -0.2691 -0.5058 1260001 Maybridge4_001058 O=C(CC1(CC2CC3CC(C2)C1)C3)NC4CCN(Cc5ccccc5)CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A03 compound treatment 0.057 -0.172 -1.81 0.053 -0.177 -2.12 -2.7767 -0.9969 3063469 Maybridge4_001059 Cn1ncc(C(=O)Sc2ccc(Cl)cc2)c1n3cccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A04 compound treatment 0.251 0.0218 0.23 0.238 0.00797 0.1 0.2292 0.9247 3179581 Maybridge4_001060 Oc1cc(nc(SCC(=O)c2ccc(Cl)s2)n1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A05 compound treatment 0.216 -0.0132 -0.14 0.2 -0.03 -0.36 -0.3522 -0.9144 3063470 Maybridge4_001061 FC(F)(F)c1ccnc(Sc2ccccc2NC(=O)Nc3ccccc3)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A06 compound treatment 0.452 0.223 2.34 0.417 0.187 2.24 3.2363 0.9997 3179582 Maybridge4_001062 CC(C)(C)c1cc(C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)n(Cc4ccc(F)cc4)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A07 compound treatment 0.223 -0.00622 -0.07 0.196 -0.034 -0.41 -0.3341 -0.8102 3063471 Maybridge4_001063 CN(/N=C/c1ncc(cc1Cl)C(F)(F)F)C(=O)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A08 compound treatment 0.247 0.0178 0.19 0.195 -0.035 -0.42 -0.1643 -0.3581 3179583 Maybridge4_001064 COC(=O)c1ccc(n1C)S(=O)(=O)NCCNc2cccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A09 compound treatment 0.216 -0.0132 -0.14 0.188 -0.042 -0.5 -0.4538 -0.8698 3063472 Maybridge4_001065 Cc1cccc(c1)n2c(CC#N)n[nH]c2=S 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A10 compound treatment 1.096 0.867 9.1 1.07 0.84 10.05 13.5434 0.9988 1646442 Maybridge4_001066 Cc1ccc2N(CC(=O)N(C3CCCCC3)c4ccccc4)CCCc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A11 compound treatment 0.259 0.0298 0.31 0.233 0.00297 0.04 0.2463 0.7824 1595838 Maybridge4_001067 COC(=O)c1sccc1S(=O)(=O)Nc2cc(OC)c(OC)cc2C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A12 compound treatment 0.314 0.0848 0.89 0.29 0.06 0.72 1.137 0.9943 3179584 Maybridge4_001068 FC(F)(F)c1ccc(N2CCc3ccccc3C2)c(NC(=O)c4ccccc4)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A13 compound treatment 0.181 -0.0482 -0.51 0.167 -0.063 -0.75 -0.8914 -0.9812 3063473 Maybridge4_001069 FC(F)(F)C1=NCCN(C=C1)S(=O)(=O)c2ccc(CNC(=O)c3ccccc3)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A14 compound treatment 0.233 0.00378 0.04 0.188 -0.042 -0.5 -0.3275 -0.6492 1536339 Maybridge4_001070 OC(=O)COCC(=O)N1CCCN(CC1)c2nc3ccc(Cl)cc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A15 compound treatment 0.199 -0.0302 -0.32 0.16 -0.07 -0.84 -0.8169 -0.9117 1391994 Maybridge4_001071 CCOC(=O)C1CCN(CC1)c2ncnc3cc(OC)c(OC)cc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A16 compound treatment 0.504 0.275 2.89 0.425 0.195 2.33 3.6901 0.9944 1501197 Maybridge4_001072 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCC3CCN(CC3)C(=O)OC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A17 compound treatment 0.193 -0.0362 -0.38 0.205 -0.025 -0.3 -0.4808 -0.993 1440783 Maybridge4_001073 COc1cc(cc(OC)c1OC)C(CC(=O)O)CC(=O)N2CCC(CC2)n3cccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A18 compound treatment 0.167 -0.0622 -0.65 0.149 -0.081 -0.97 -1.1476 -0.9816 1175173 Maybridge4_001074 CC(C)(C)c1ccc(cc1)c2noc(n2)c3ccc4OCCc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A19 compound treatment 0.389 0.16 1.68 0.358 0.128 1.53 2.2692 0.999 1213784 Maybridge4_001075 NC(=O)C1CCN(CN2C(=O)c3ccccc3C2=O)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A20 compound treatment 0.243 0.0138 0.14 0.218 -0.012 -0.14 6.0E-4 0.0027 1134687 Maybridge4_001076 OC(=O)c1nccnc1C(=O)Nc2ccc(cc2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A21 compound treatment 0.411 0.182 1.91 0.38 0.15 1.79 2.6187 0.9995 3063474 Maybridge4_001077 FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A22 compound treatment 0.462 0.233 2.44 0.39 0.16 1.91 3.0821 0.9927 3179585 Maybridge4_001078 COc1ccccc1N2CCN(CC2)C(=O)c3cnn(c3C)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A23 mock treatment 0.204 -0.0252 -0.26 0.197 -0.033 -0.4 -0.4667 -0.9811 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 A24 mock treatment 0.217 -0.0122 -0.13 0.227 -0.00303 -0.04 -0.1164 -0.8728 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B01 compound treatment 0.219 -0.0102 -0.11 0.175 -0.055 -0.66 -0.5415 -0.8117 1733246 Maybridge4_001079 Cc1cnc(cn1)C(=O)Nc2nnn[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B02 compound treatment 0.184 -0.0452 -0.47 0.159 -0.071 -0.85 -0.9368 -0.9622 1403239 Maybridge4_001080 NC(=O)C1CCN(CC(O)COc2ccc(cc2)c3csnn3)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B03 compound treatment 0.191 -0.0382 -0.4 0.185 -0.045 -0.54 -0.6648 -0.9895 1480432 Maybridge4_001081 COc1ccc(cc1OC)S(=O)(=O)NCCN2CCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B04 compound treatment 0.502 0.273 2.86 0.476 0.246 2.94 4.1067 0.9999 3179682 Maybridge4_001082 Cc1ccsc1CNC(=O)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B05 compound treatment 0.209 -0.0202 -0.21 0.163 -0.067 -0.8 -0.7173 -0.8645 1539091 Maybridge4_001083 OC(=O)c1cc(ccc1O)S(=O)(=O)NCCN2CCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B06 compound treatment 0.236 0.00678 0.07 0.178 -0.052 -0.62 -0.3898 -0.6222 1590468 Maybridge4_001084 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B07 compound treatment 0.223 -0.00622 -0.07 0.181 -0.049 -0.59 -0.461 -0.781 1660094 Maybridge4_001085 Cc1nn(nc1C(=O)NC2CCS(=O)(=O)C2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B08 compound treatment 0.186 -0.0432 -0.45 0.166 -0.064 -0.77 -0.8627 -0.9688 1742612 Maybridge4_001086 COc1ccc(SCC(=O)NCc2ccc3OCOc3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B09 compound treatment 0.227 -0.00222 -0.02 0.163 -0.067 -0.8 -0.5836 -0.7273 3179683 Maybridge4_001087 CCOC(=O)c1c(NC(=O)NC(C)(C)C)sc2CN(C)CCc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B10 compound treatment 0.097 -0.132 -1.39 0.089 -0.141 -1.69 -2.1751 -0.9953 1477333 Maybridge4_001088 Cc1cc(NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)n(C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B11 compound treatment 0.258 0.0288 0.3 0.264 0.034 0.41 0.5011 0.9894 1603040 Maybridge4_001089 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccc5OCCc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B12 compound treatment 0.886 0.657 6.9 0.801 0.571 6.83 9.7081 1.0 3179684 Maybridge4_001090 Cn1c(SCC(=O)c2ccc3OCCOc3c2)nnc1c4ccc5ccccc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B13 compound treatment 0.358 0.129 1.35 0.349 0.119 1.42 1.9629 0.9997 3063475 Maybridge4_001091 CN(C(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2)c3nnc(s3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B14 compound treatment 1.24 1.01 10.62 1.249 1.02 12.19 16.1272 0.9976 3179685 Maybridge4_001092 CCOC(=O)c1c(C)n(c(C)c1/C=C/2\C(=O)Nc3ccccc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B15 compound treatment 0.206 -0.0232 -0.24 0.201 -0.029 -0.35 -0.4181 -0.985 1321807 Maybridge4_001093 Cn1nc(cc1C(=O)NN2CCOCC2)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B16 compound treatment 0.271 0.0418 0.44 0.231 9.68E-4 0.01 0.3185 0.7255 3179686 Maybridge4_001094 Cc1ccc(cc1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B17 compound treatment 0.277 0.0478 0.5 0.234 0.00397 0.05 0.3884 0.7706 1191907 Maybridge4_001095 O=C1NCCN1CCNC(=S)NC2CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B18 compound treatment 0.25 0.0208 0.22 0.214 -0.016 -0.19 0.0187 0.0643 1709557 Maybridge4_001096 COc1ccc(OCC(O)CNC(=O)c2c(C)onc2c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B19 compound treatment 0.574 0.345 3.62 0.52 0.29 3.47 5.0137 0.9998 1259000 Maybridge4_001097 CCCc1c(cnn1c2ccccc2)C(=O)N(Cc3cccs3)Cc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B20 compound treatment 0.226 -0.00322 -0.03 0.189 -0.041 -0.49 -0.371 -0.754 1607244 Maybridge4_001098 O=C(N1CCN(CCN2CCOCC2)CC1)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B21 compound treatment 0.708 0.479 5.03 0.608 0.378 4.52 6.7533 0.9986 1594969 Maybridge4_001099 CCCc1c(cnn1c2ccccc2)C(=O)Nc3nc[nH]n3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B22 compound treatment 0.365 0.136 1.43 0.353 0.123 1.47 2.0487 0.9999 3063476 Maybridge4_001100 Clc1ccc(Sc2cccc(Cl)c2Cn3cccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B23 mock treatment 0.221 -0.00822 -0.09 0.216 -0.014 -0.17 -0.1798 -0.9522 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 B24 mock treatment 0.195 -0.0342 -0.36 0.215 -0.015 -0.18 -0.3813 -0.9488 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C01 compound treatment 0.173 -0.0562 -0.59 0.152 -0.078 -0.93 -1.0777 -0.9756 3179687 Maybridge4_001101 Cc1cc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C=CC3=O)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C02 compound treatment 0.433 0.204 2.14 0.326 0.096 1.15 2.3253 0.9574 1404378 Maybridge4_001102 OC1(CCN(CC1)C(=O)CC2(CC3CC4CC(C3)C2)C4)c5ccc(Cl)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C03 compound treatment 0.192 -0.0372 -0.39 0.185 -0.045 -0.54 -0.6574 -0.9876 1249628 Maybridge4_001103 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3ncnc4cc(sc34)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C04 compound treatment 0.213 -0.0162 -0.17 0.184 -0.046 -0.55 -0.5099 -0.8845 3063496 Maybridge4_001104 Fc1ccc(NC(=O)NCc2nc(no2)c3ccc(cc3)C(F)(F)F)c(F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C05 compound treatment 0.17 -0.0592 -0.62 0.151 -0.079 -0.95 -1.1084 -0.9793 3063497 Maybridge4_001105 OC(CSc1ccccc1NC(=O)/C=C\C(=O)O)Cn2ccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C06 compound treatment 0.24 0.0108 0.11 0.187 -0.043 -0.51 -0.284 -0.5387 3063498 Maybridge4_001106 Cn1nc(c(c1NC(=O)c2nccnc2C(=O)O)c3cccc(c3)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C07 compound treatment 0.422 0.193 2.02 0.43 0.2 2.39 3.1234 0.9966 3179688 Maybridge4_001107 CN(/N=C/c1ncc(cc1Cl)C(F)(F)F)C(=O)Nc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C08 compound treatment 0.409 0.18 1.89 0.333 0.103 1.23 2.2063 0.9786 3063499 Maybridge4_001108 FC(F)(F)C1=NCCN(C=C1)C(=O)C2CCN(CC2)c3nccc(n3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C09 compound treatment 0.24 0.0108 0.11 0.199 -0.031 -0.37 -0.1825 -0.4701 1483010 Maybridge4_001109 COc1ccc(CN(Cc2cccn2C)C(=O)c3cc4cc(OC)ccc4[nH]3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C10 compound treatment 0.328 0.0988 1.04 0.073 -0.157 -1.88 -0.5949 -0.2772 1408441 Maybridge4_001110 COC(=O)c1sc(cc1NC(=O)COCC(=O)O)c2ccc(cc2)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C11 compound treatment 1.248 1.02 10.7 1.149 0.919 10.99 15.3406 0.9999 3179689 Maybridge4_001111 FC(F)(F)c1cc(N2CCN(CC2)C(=O)C3CCC3)c4ccccc4n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C12 compound treatment 0.424 0.195 2.05 0.354 0.124 1.48 2.4953 0.9875 3063500 Maybridge4_001112 FC(F)(F)c1oc(cc1C(=O)NCc2cccs2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C13 compound treatment 0.443 0.214 2.25 0.425 0.195 2.33 3.2371 0.9998 3179690 Maybridge4_001113 CCC(=O)N(C)c1nc(cs1)c2ccc(Cl)s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C14 compound treatment 0.101 -0.128 -1.35 0.093 -0.137 -1.64 -2.1115 -0.9952 3179691 Maybridge4_001114 Fc1ccc(cc1)S(=O)(=O)Nc2ccccc2NC3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C15 compound treatment 0.107 -0.122 -1.28 0.098 -0.132 -1.58 -2.0247 -0.9947 1317474 Maybridge4_001115 COc1cccc(Cl)c1NC(=O)N2CCN(CC2)c3cc(C)nc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C16 compound treatment 0.304 0.0748 0.79 0.321 0.091 1.09 1.325 0.9872 3179692 Maybridge4_001116 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C17 compound treatment 0.191 -0.0382 -0.4 0.169 -0.061 -0.73 -0.8002 -0.9603 1139184 Maybridge4_001117 COc1ccc(CC2CCC3(CC2)NC(=O)c4ccccc4O3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C18 compound treatment 0.321 0.0918 0.96 0.239 0.00897 0.11 0.7575 0.781 1486833 Maybridge4_001118 COC(=O)c1cc(oc1C)S(=O)(=O)NCC2CN(Cc3ccccc3)CN(Cc4ccccc4)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C19 compound treatment 0.442 0.213 2.23 0.445 0.215 2.57 3.3989 0.9975 1538683 Maybridge4_001119 OC1(CCN(CN2C(=O)c3ccccc3C2=O)CC1)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C20 compound treatment 0.206 -0.0232 -0.24 0.201 -0.029 -0.35 -0.4181 -0.985 3063501 Maybridge4_001120 OC(=O)/C=C/C(=O)Nc1ccc(nc1N2CCOCC2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C21 compound treatment 0.191 -0.0382 -0.4 0.167 -0.063 -0.75 -0.8171 -0.9564 1658419 Maybridge4_001121 NC(=O)C1CCN(CC(O)CSc2ccc(F)cc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C22 compound treatment 0.238 0.00878 0.09 0.231 9.68E-4 0.01 0.0734 0.7897 1233858 Maybridge4_001122 CS(=O)(=O)CS(=O)(=O)Nc1ccc2OCCOc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C23 mock treatment 0.213 -0.0162 -0.17 0.242 0.012 0.14 -0.0192 -0.0863 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 C24 mock treatment 0.246 0.0168 0.18 0.232 0.00197 0.02 0.1413 0.7945 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D01 compound treatment 0.22 -0.00922 -0.1 0.181 -0.049 -0.59 -0.4833 -0.8128 1662148 Maybridge4_001123 Cc1nc(cn1C)S(=O)(=O)NC2CCS(=O)(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D02 compound treatment 0.165 -0.0642 -0.67 0.144 -0.086 -1.03 -1.2048 -0.979 1341736 Maybridge4_001124 CCN(CC)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D03 compound treatment 0.429 0.2 2.1 0.272 0.042 0.5 1.8387 0.8523 3063502 Maybridge4_001125 Cn1cnc(c1)S(=O)(=O)NCC2CCN(CC2)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D04 compound treatment 0.661 0.432 4.53 0.679 0.449 5.37 7.005 0.9965 3179693 Maybridge4_001126 Cc1nnc(Sc2nc3ccc(Cl)cc3s2)n1c4ccc5OCCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D05 compound treatment 0.247 0.0178 0.19 0.232 0.00197 0.02 0.1487 0.79 1259497 Maybridge4_001127 O=C1NCCN1CCNS(=O)(=O)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D06 compound treatment 0.24 0.0108 0.11 0.163 -0.067 -0.8 -0.487 -0.6013 1281709 Maybridge4_001128 OC(=O)CSCC(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D07 compound treatment 0.134 -0.0952 -1.0 0.112 -0.118 -1.41 -1.7057 -0.9857 1146339 Maybridge4_001129 CCCCc1ccc(cc1)n2c(coc2=O)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D08 compound treatment 0.318 0.0888 0.93 0.286 0.056 0.67 1.1328 0.9868 1522891 Maybridge4_001130 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3cn(C)cn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D09 compound treatment 0.323 0.0938 0.98 0.268 0.038 0.45 1.0177 0.9382 3063503 Maybridge4_001131 FC(F)(F)c1nn2c(=O)cc([nH]c2c1c3ccccc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D10 compound treatment 0.133 -0.0962 -1.01 0.089 -0.141 -1.69 -1.9077 -0.9699 1088065 Maybridge4_001132 Cc1cc(C(=O)Nc2ccccc2)c(C)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D11 compound treatment 0.42 0.191 2.0 0.429 0.199 2.38 3.1001 0.9963 1383227 Maybridge4_001133 O=C(OCCn1ncc2ccccc2c1=O)c3ccc4OCCc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D12 compound treatment 1.346 1.12 11.73 1.333 1.1 13.2 17.625 0.9983 1524796 Maybridge4_001134 Cc1ccc(cc1)c2cc(Cc3ccccc3)c(=O)[nH]n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D13 compound treatment 0.334 0.105 1.1 0.264 0.034 0.41 1.0655 0.9083 1531019 Maybridge4_001135 Cc1c(csc1C(=O)N(Cc2ccccc2)Cc3cccnc3)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D14 compound treatment 0.194 -0.0352 -0.37 0.196 -0.034 -0.41 -0.5495 -0.9989 3063504 Maybridge4_001136 OC(=O)c1nccnc1C(=O)Nc2ccc(CC#N)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D15 compound treatment 0.316 0.0868 0.91 0.203 -0.027 -0.32 0.4158 0.4299 1469748 Maybridge4_001137 CSc1nsc(SC)c1C(=O)NN2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D16 compound treatment 0.267 0.0378 0.4 0.244 0.014 0.17 0.3988 0.9261 3063505 Maybridge4_001138 Fc1ccc(cc1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D17 compound treatment 0.252 0.0228 0.24 0.212 -0.018 -0.22 0.0166 0.0516 3179791 Maybridge4_001139 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccc3COC(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D18 compound treatment 0.314 0.0848 0.89 0.245 0.015 0.18 0.7563 0.8326 3179792 Maybridge4_001140 COc1ccc(OCC(O)CNC(=O)c2ccc(OC(F)(F)F)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D19 compound treatment 0.849 0.62 6.51 0.879 0.649 7.76 10.0932 0.9962 1658181 Maybridge4_001141 CCCc1c(cnn1c2ccccc2)C(=O)NCc3ccc4OCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D20 compound treatment 0.28 0.0508 0.53 0.225 -0.00503 -0.06 0.3346 0.6233 1302806 Maybridge4_001142 CCOC(=O)N1CCC(CC1)NC(=O)Nc2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D21 compound treatment 0.245 0.0158 0.17 0.208 -0.022 -0.26 -0.0692 -0.2222 1417198 Maybridge4_001143 COc1cccc2n(C)nc(NC(=O)CCC(=O)O)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D22 compound treatment 0.221 -0.00822 -0.09 0.227 -0.00303 -0.04 -0.0867 -0.9258 1130087 Maybridge4_001144 COc1ccc(OCC(O)CNC(=O)Nc2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D23 mock treatment 0.208 -0.0212 -0.22 0.203 -0.027 -0.32 -0.3863 -0.9835 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 D24 mock treatment 0.2 -0.0292 -0.31 0.212 -0.018 -0.22 -0.3695 -0.9851 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E01 compound treatment 0.181 -0.0482 -0.51 0.204 -0.026 -0.31 -0.5783 -0.9727 1356815 Maybridge4_001145 Cn1ncc2c(NN3C(=O)CCC3=O)ncnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E02 compound treatment 0.16 -0.0692 -0.73 0.149 -0.081 -0.97 -1.1996 -0.9899 3063506 Maybridge4_001146 FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)N3CCN(Cc4ccccc4)CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E03 compound treatment 0.624 0.395 4.15 0.636 0.406 4.86 6.3664 0.9969 3179793 Maybridge4_001147 COC(=O)c1sc(cc1NS(=O)(=O)c2ccc(C)cc2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E04 compound treatment 0.243 0.0138 0.14 0.223 -0.00703 -0.08 0.0429 0.256 1593578 Maybridge4_001148 Cc1noc(C)c1n2sc(=O)n(CC3CC3)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E05 compound treatment 0.644 0.415 4.36 0.599 0.369 4.41 6.2019 1.0 1366685 Maybridge4_001149 OC(CSc1ccccc1NC(=O)c2ccc(Cl)cc2)Cn3ccc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E06 compound treatment 0.13 -0.0992 -1.04 0.121 -0.109 -1.3 -1.6593 -0.9938 1718437 Maybridge4_001150 CCCCc1ccc(NC(=O)N2CCN(CC2)c3cc(C)nc4ccccc34)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E07 compound treatment 0.362 0.133 1.39 0.251 0.021 0.25 1.1635 0.8211 3063507 Maybridge4_001151 CNC(=S)NC1CC2CCC1C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E08 compound treatment 0.093 -0.136 -1.43 0.147 -0.083 -0.99 -1.7141 -0.9841 1663721 Maybridge4_001152 Fc1ccc(cc1Cl)n2sc(=O)n(C3Cc4ccccc4C3)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E09 compound treatment 0.49 0.261 2.74 0.412 0.182 2.18 3.4762 0.9935 3063508 Maybridge4_001153 Cc1nnsc1c2nc(cs2)c3ccc(Cl)s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E10 compound treatment 0.274 0.0448 0.47 0.268 0.038 0.45 0.6538 0.9998 1128288 Maybridge4_001154 COC(=O)c1ccc(n1C)S(=O)(=O)N(Cc2ccccc2)Cc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E11 compound treatment 0.241 0.0118 0.12 0.186 -0.044 -0.53 -0.285 -0.5267 1703913 Maybridge4_001155 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2cccc(c2)c3cnco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E12 compound treatment 0.338 0.109 1.14 0.295 0.065 0.78 1.3575 0.9824 1704448 Maybridge4_001156 Cc1cccc(Cl)c1n2sc(=O)n(CC3CC3)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E13 compound treatment 0.31 0.0808 0.85 0.324 0.094 1.12 1.3949 0.9904 1205718 Maybridge4_001157 CN(C(=O)C1CCCCC1)c2nc(cs2)c3ccc(Cl)s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E14 compound treatment 0.484 0.255 2.68 0.64 0.41 4.91 5.3605 0.9594 3179794 Maybridge4_001158 Cc1ccc(OCC(O)CNc2ccc(Br)c(c2)C(F)(F)F)cc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E15 compound treatment 0.266 0.0368 0.39 0.219 -0.011 -0.13 0.1798 0.4405 3063509 Maybridge4_001159 OC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E16 compound treatment 0.287 0.0578 0.61 0.269 0.039 0.47 0.7588 0.9915 1390204 Maybridge4_001160 Cn1cnc(c1)S(=O)(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E17 compound treatment 0.225 -0.00422 -0.04 0.225 -0.00503 -0.06 -0.0739 -0.9886 1537127 Maybridge4_001161 COc1ccccc1NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E18 compound treatment 0.241 0.0118 0.12 0.19 -0.04 -0.48 -0.2512 -0.5078 1388804 Maybridge4_001162 COc1ccc(cc1)C(=O)CN2CCCc3cc(C)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E19 compound treatment 0.421 0.192 2.01 0.368 0.138 1.65 2.5915 0.9951 1307254 Maybridge4_001163 COc1ccc(CN(Cc2cccn2C)S(=O)(=O)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E20 compound treatment 0.231 0.00178 0.02 0.184 -0.046 -0.55 -0.3762 -0.6827 1235221 Maybridge4_001164 Fc1cccc(Cl)c1CN2CCC(CC2)NS(=O)(=O)c3cccc4nonc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E21 compound treatment 0.393 0.164 1.72 0.3 0.07 0.84 1.8083 0.9452 3179795 Maybridge4_001165 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E22 compound treatment 0.299 0.0698 0.73 0.296 0.066 0.79 1.0763 0.9993 1482186 Maybridge4_001166 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E23 mock treatment 0.198 -0.0312 -0.33 0.22 -0.01 -0.12 -0.3167 -0.9071 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 E24 mock treatment 0.208 -0.0212 -0.22 0.206 -0.024 -0.29 -0.3609 -0.9921 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F01 compound treatment 0.193 -0.0362 -0.38 0.163 -0.067 -0.8 -0.8361 -0.9419 3063510 Maybridge4_001167 Fc1cccc(Cl)c1CN2CCC(CC2)NS(=O)(=O)c3ccc(cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F02 compound treatment 0.138 -0.0912 -0.96 0.14 -0.09 -1.08 -1.4391 -0.9983 1623040 Maybridge4_001168 CCN(CC)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F03 compound treatment 1.235 1.01 10.56 1.133 0.903 10.8 15.1087 0.9999 1283930 Maybridge4_001169 C1C(Cc2ccccc12)Nc3nc(ns3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F04 compound treatment 1.311 1.08 11.36 1.283 1.05 12.6 16.9421 0.9987 3179796 Maybridge4_001170 CC(C)(CC(=O)O)CC(=O)Nc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F05 compound treatment 0.287 0.0578 0.61 0.231 9.68E-4 0.01 0.4373 0.7205 3063512 Maybridge4_001171 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCN2CCNC2=O)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F06 compound treatment 0.241 0.0118 0.12 0.216 -0.014 -0.17 -0.0312 -0.1497 1430388 Maybridge4_001172 Cc1ccc(NC(=O)c2ccsc2)cc1NS(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F07 compound treatment 0.296 0.0668 0.7 0.266 0.036 0.43 0.8002 0.9725 1313330 Maybridge4_001173 Cc1oc(cc1C(=O)NCc2ccc3OCOc3c2)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F08 compound treatment 0.318 0.0888 0.93 0.29 0.06 0.72 1.1667 0.9916 3063513 Maybridge4_001174 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3ccc(cc3Cl)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F09 compound treatment 0.089 -0.14 -1.47 0.091 -0.139 -1.66 -2.2176 -0.9982 1684282 Maybridge4_001175 COC(=O)c1sccc1c2ccc(CN3CCC(CC3)c4ccccc4OC)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F10 compound treatment 0.212 -0.0172 -0.18 0.192 -0.038 -0.46 -0.4496 -0.9183 1364415 Maybridge4_001176 Cc1oc(cc1C(=O)NC2Cc3ccccc3C2)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F11 compound treatment 0.317 0.0878 0.92 0.284 0.054 0.65 1.1085 0.9848 3063529 Maybridge4_001177 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)c3ccc4OCCc4c3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F12 compound treatment 0.542 0.313 3.29 0.532 0.302 3.61 4.8776 0.9989 1341364 Maybridge4_001178 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)C4CCC4)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F13 compound treatment 0.265 0.0358 0.38 0.237 0.00697 0.08 0.3247 0.8435 3063530 Maybridge4_001179 O=C(NCCN1CCN(Cc2ccccc2)CC1)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F14 compound treatment 0.27 0.0408 0.43 0.242 0.012 0.14 0.4041 0.8948 1693889 Maybridge4_001180 O=C(Nc1ccccc1)Nc2ccc(CC#N)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F15 compound treatment 0.281 0.0518 0.54 0.228 -0.00203 -0.02 0.3674 0.6748 3063531 Maybridge4_001181 Cc1nc(ccc1C(=O)NN2CCOCC2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F16 compound treatment 0.422 0.193 2.02 0.363 0.133 1.59 2.5566 0.9929 1169808 Maybridge4_001182 O=C(Nc1cccc2ccccc12)N3CCN(CC3)c4ncccc4C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F17 compound treatment 0.525 0.296 3.11 0.488 0.258 3.09 4.3791 1.0 3179797 Maybridge4_001183 Cc1onc(c1C(=O)N(C(=O)c2c(C)onc2c3ccccc3)c4ncc(C)nc4C)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F18 compound treatment 0.661 0.432 4.53 0.545 0.315 3.77 5.8713 0.9958 1265508 Maybridge4_001184 COc1ccc(OCC(O)CNC(=O)c2sccc2Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F19 compound treatment 0.414 0.185 1.94 0.309 0.079 0.94 2.0404 0.9453 3063532 Maybridge4_001185 COC(=O)c1cnc(nc1C(F)(F)F)N2CCCN(CC2)C(=O)c3cc(nn3C)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F20 compound treatment 0.252 0.0228 0.24 0.206 -0.024 -0.29 -0.0341 -0.0912 3179798 Maybridge4_001186 CCOC(=O)N1CCC(CC1)NC(=O)Nc2cc(C)oc2C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F21 compound treatment 0.189 -0.0402 -0.42 0.22 -0.01 -0.12 -0.3836 -0.8735 1597233 Maybridge4_001187 COc1cccc2n(C)nc(NC(=O)CSCC(=O)O)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F22 compound treatment 0.336 0.107 1.12 0.287 0.057 0.68 1.275 0.9715 1439715 Maybridge4_001188 CCc1ccc(cc1)S(=O)(=O)NCC(O)COc2ccc(OC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F23 mock treatment 0.232 0.00278 0.03 0.207 -0.023 -0.28 -0.1742 -0.6286 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 F24 mock treatment 0.209 -0.0202 -0.21 0.249 0.019 0.23 0.0103 0.0332 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G01 compound treatment 0.177 -0.0522 -0.55 0.159 -0.071 -0.85 -0.9887 -0.9775 1075387 Maybridge4_001189 NC(=O)NC1CCCCCCC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G02 compound treatment 0.253 0.0238 0.25 0.218 -0.012 -0.14 0.0748 0.2595 1679776 Maybridge4_001190 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NC2CCCCCCCCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G03 compound treatment 0.308 0.0788 0.83 0.211 -0.019 -0.23 0.4241 0.4941 3063533 Maybridge4_001191 COC(=O)c1cnc(nc1C(F)(F)F)n2ncc(C#N)c2N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G04 compound treatment 0.29 0.0608 0.64 0.219 -0.011 -0.13 0.3581 0.5493 1394712 Maybridge4_001192 OCCN1CCN(CC1)C2=Cc3ccccc3C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G05 compound treatment 0.616 0.387 4.06 0.579 0.349 4.18 5.8247 0.9999 1644505 Maybridge4_001193 CC(C)(C)NC(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G06 compound treatment 0.287 0.0578 0.61 0.275 0.045 0.54 0.8095 0.9982 3063534 Maybridge4_001194 OC(=O)COCC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G07 compound treatment 0.591 0.362 3.8 0.58 0.35 4.19 5.6475 0.9988 1201054 Maybridge4_001195 COc1ccccc1NC(=S)NC2CC3CCC2C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G08 compound treatment 0.16 -0.0692 -0.73 0.161 -0.069 -0.83 -1.0981 -0.998 1231183 Maybridge4_001196 CCOC(=O)c1cccc(c1)n2sc(=O)n(C3Cc4ccccc4C3)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G09 compound treatment 0.487 0.258 2.71 0.538 0.308 3.68 4.5199 0.9885 1624776 Maybridge4_001197 Clc1ccc(s1)c2csc(n2)c3ccc4OCCc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G10 compound treatment 0.361 0.132 1.38 0.31 0.08 0.96 1.6552 0.9837 1282547 Maybridge4_001198 COC(=O)c1ccc(n1C)S(=O)(=O)N(C2CCCCC2)C3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G11 compound treatment 0.442 0.213 2.23 0.413 0.183 2.19 3.1282 0.9999 3063535 Maybridge4_001199 COC(=O)c1cc(oc1C)S(=O)(=O)Nc2cccc(c2)c3cnco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G12 compound treatment 0.392 0.163 1.71 0.333 0.103 1.23 2.08 0.9871 3063536 Maybridge4_001200 FC(F)(F)c1ccccc1n2sc(=O)n(CC3CC3)c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G13 compound treatment 0.36 0.131 1.37 0.369 0.139 1.66 2.1469 0.9955 3178224 Maybridge4_001201 COc1ccc(Oc2ccc(cc2NS(=O)(=O)c3cccc4nonc34)C(F)(F)F)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G14 compound treatment 0.222 -0.00722 -0.08 0.181 -0.049 -0.59 -0.4684 -0.7919 3178225 Maybridge4_001202 FC(F)(F)c1cc(NC(=O)c2ccc(CN3C(=O)c4ccccc4C3=O)o2)ccc1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G15 compound treatment 0.284 0.0548 0.58 0.223 -0.00703 -0.08 0.3473 0.5973 3063537 Maybridge4_001203 OC(=O)c1sccc1S(=O)(=O)Nc2ccccc2N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G16 compound treatment 0.418 0.189 1.98 0.339 0.109 1.3 2.3239 0.9793 1305367 Maybridge4_001204 CC(C)(C)OC(=O)N1CCC(CNC(=O)Nc2ccccc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G17 compound treatment 0.658 0.429 4.5 0.654 0.424 5.07 6.7712 0.9982 1532622 Maybridge4_001205 Clc1ccc(cc1Cl)n2c(SCC(=O)N3CCOCC3)nc4ccccc4c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G18 compound treatment 0.508 0.279 2.93 0.427 0.197 2.36 3.7367 0.9942 1304189 Maybridge4_001206 Fc1ccc(cc1)c2ccc(=O)n(CCC#N)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G19 compound treatment 0.21 -0.0192 -0.2 0.194 -0.036 -0.43 -0.4476 -0.9402 1675293 Maybridge4_001207 Cn1nc(NC(=O)C2CCC2C(=O)O)c3c(F)cccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G20 compound treatment 0.376 0.147 1.54 0.363 0.133 1.59 2.215 0.9999 1345399 Maybridge4_001208 COC(=O)c1sccc1NC(=O)c2cc(oc2C)S(=O)(=O)N(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G21 compound treatment 0.386 0.157 1.65 0.333 0.103 1.23 2.0355 0.9898 1463889 Maybridge4_001209 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4ccc(C)c5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G22 compound treatment 0.303 0.0738 0.77 0.255 0.025 0.3 0.7592 0.9141 1398688 Maybridge4_001210 Cc1cc(NS(=O)(=O)c2ccc3OCCOc3c2)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G23 mock treatment 0.208 -0.0212 -0.22 0.214 -0.016 -0.19 -0.2932 -0.9972 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 G24 mock treatment 0.243 0.0138 0.14 0.22 -0.01 -0.12 0.0175 0.0929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H01 compound treatment 0.181 -0.0482 -0.51 0.182 -0.048 -0.57 -0.7645 -0.998 1708371 Maybridge4_001211 OC(=O)COCC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H02 compound treatment 0.263 0.0338 0.35 0.198 -0.032 -0.38 -0.0201 -0.0385 3063538 Maybridge4_001212 Clc1ccc2nc(Sc3ccccc3NS(=O)(=O)c4ccc(C#N)cc4)sc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H03 compound treatment 0.175 -0.0542 -0.57 0.14 -0.09 -1.08 -1.1643 -0.9556 1419067 Maybridge4_001213 Cc1c(cnn1c2ccc(F)cc2)C(=O)N(Cc3ccccc3)Cc4cccnc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H04 compound treatment 0.236 0.00678 0.07 0.205 -0.025 -0.3 -0.1614 -0.5243 1711883 Maybridge4_001214 NS(=O)(=O)c1ccc(NC(=O)CC2(CC(=O)O)CCCC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H05 compound treatment 0.297 0.0678 0.71 0.285 0.055 0.66 0.9684 0.9992 1352488 Maybridge4_001215 Clc1c(sc2ccccc12)C(=O)NCCN3CCNC3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H06 compound treatment 0.348 0.119 1.25 0.358 0.128 1.53 1.9648 0.9948 3178226 Maybridge4_001216 FC(F)(F)c1cc(no1)c2cc(cs2)S(=O)(=O)Nc3ccc4OCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H07 compound treatment 0.199 -0.0302 -0.32 0.227 -0.00303 -0.04 -0.2501 -0.7828 1151414 Maybridge4_001217 COc1ccccc1OCC(O)CNCc2ccc3OCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H08 compound treatment 0.148 -0.0812 -0.85 0.135 -0.095 -1.14 -1.4072 -0.99 1595899 Maybridge4_001218 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)c3ccccc3C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H09 compound treatment 1.147 0.918 9.64 1.126 0.896 10.72 14.3959 0.9986 3063539 Maybridge4_001219 CC(C)n1c(SCC(=O)Nc2ccccc2Cl)nc3cc(Cl)ccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H10 compound treatment 0.271 0.0418 0.44 0.23 -3.23E-5 0.0 0.31 0.7065 3178227 Maybridge4_001220 Cc1nc(ccc1C(=O)Nc2ccccc2c3ccccc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H11 compound treatment 0.627 0.398 4.18 0.629 0.399 4.77 6.3294 0.9978 1134518 Maybridge4_001221 CN(C(=O)c1ccc(Cl)cc1)c2ccc(Cl)cc2C(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H12 compound treatment 0.26 0.0308 0.32 0.25 0.02 0.24 0.3975 0.9889 1256492 Maybridge4_001222 CCCc1ccc(cc1)S(=O)(=O)Nc2ccc(C)c(NS(=O)(=O)C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H13 compound treatment 0.329 0.0998 1.05 0.29 0.06 0.72 1.2484 0.9829 1621469 Maybridge4_001223 CCOC(=O)C1=C(NC(=O)NC1C)C(C)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H14 compound treatment 0.35 0.121 1.27 0.322 0.092 1.1 1.675 0.9975 1158832 Maybridge4_001224 CCc1ccnc(NC(=O)Nc2ccccc2C(C)(C)C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H15 compound treatment 0.239 0.00978 0.1 0.202 -0.028 -0.34 -0.1645 -0.469 3178228 Maybridge4_001225 O=S(=O)(NN1CCOCC1)c2cc(cs2)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H16 compound treatment 0.402 0.173 1.81 0.425 0.195 2.33 2.9326 0.9923 1405785 Maybridge4_001226 Clc1cncc(Cl)c1N2CCCN(CC2)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H17 compound treatment 0.678 0.449 4.71 0.592 0.362 4.33 6.3952 0.9991 3178229 Maybridge4_001227 Cn1c(Cc2ccsc2)nnc1Sc3nc4ccc(Cl)cc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H18 compound treatment 0.367 0.138 1.45 0.346 0.116 1.39 2.0043 0.9998 1596031 Maybridge4_001228 COc1ccc(OCC(O)CNC(=O)c2ccc(cc2)N(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H19 compound treatment 0.241 0.0118 0.12 0.201 -0.029 -0.35 -0.1581 -0.4288 1496534 Maybridge4_001229 COC(=O)c1ccc(n1C)S(=O)(=O)NN2CCOCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H20 compound treatment 0.281 0.0518 0.54 0.245 0.015 0.18 0.5112 0.8928 1382593 Maybridge4_001230 CCOC(=O)N1CCC(CC1)NC(=O)Nc2ccc3OCCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H21 compound treatment 0.261 0.0318 0.33 0.223 -0.00703 -0.08 0.1765 0.5128 1574673 Maybridge4_001231 COc1cccc2n(C)nc(NC(=O)c3nccnc3C(=O)O)c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H22 compound treatment 0.485 0.256 2.69 0.444 0.214 2.56 3.7098 0.9997 1461069 Maybridge4_001232 CCOc1ccccc1NC(=O)N2CCCN(CC2)c3ncccc3C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H23 mock treatment 0.236 0.00678 0.07 0.214 -0.016 -0.19 -0.0853 -0.4168 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 H24 mock treatment 0.218 -0.0112 -0.12 0.211 -0.019 -0.23 -0.2443 -0.953 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I01 compound treatment 0.334 0.105 1.1 0.313 0.083 0.99 1.4801 0.9987 1638533 Maybridge4_001233 CC(C)(C)c1ccc(cc1)c2cc(NS(=O)(=O)c3ccccc3)c(s2)C(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I02 compound treatment 0.322 0.0928 0.97 0.258 0.028 0.33 0.9257 0.8984 3178230 Maybridge4_001234 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NCc2ccc(OC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I03 compound treatment 0.286 0.0568 0.6 0.208 -0.022 -0.26 0.2353 0.3609 1615822 Maybridge4_001235 CCC(CO)NC(=S)Nc1ccsc1C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I04 compound treatment 0.371 0.142 1.49 0.261 0.031 0.37 1.3149 0.8569 1181672 Maybridge4_001236 COc1ccc(cc1)n2nnnc2c3c[nH]c4ccc(Cl)cc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I05 compound treatment 0.265 0.0358 0.38 0.203 -0.027 -0.32 0.037 0.0747 3178231 Maybridge4_001237 OC(=O)/C=C\C(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I06 compound treatment 0.217 -0.0122 -0.13 0.232 0.00197 0.02 -0.0741 -0.5679 1121093 Maybridge4_001238 COC(=O)c1ccc(n1C)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I07 compound treatment 0.829 0.6 6.3 0.82 0.59 7.06 9.4455 0.9984 3178232 Maybridge4_001239 CCCN(CCC)C(=S)NC1CC2CC1C=C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I08 compound treatment 0.238 0.00878 0.09 0.232 0.00197 0.02 0.0819 0.86 1340809 Maybridge4_001240 OC1CCN(CC1)C(=O)c2cccc(CN3CCN(CC3)c4nc(ns4)c5ccccc5)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I09 compound treatment 0.15 -0.0792 -0.83 0.156 -0.074 -0.89 -1.2146 -0.9995 1278544 Maybridge4_001241 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3cccc4nonc34)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I10 compound treatment 0.237 0.00778 0.08 0.232 0.00197 0.02 0.0744 0.8752 1350689 Maybridge4_001242 COC(=O)c1ccc(n1C)S(=O)(=O)NC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I11 compound treatment 0.369 0.14 1.47 0.326 0.096 1.15 1.85 0.9926 3178233 Maybridge4_001243 Cn1c(CSc2ccnc3cc(Cl)ccc23)nnc1SCC(=O)c4ccc(Cl)s4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I12 compound treatment 1.435 1.21 12.66 1.421 1.19 14.25 19.0305 0.9983 3063555 Maybridge4_001244 O/C(=C\Sc1nc2CCCCc2c(c1C#N)C(F)(F)F)/c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I13 compound treatment 0.226 -0.00322 -0.03 0.175 -0.055 -0.66 -0.4895 -0.7424 1516805 Maybridge4_001245 COC(=O)Cc1nc(NC(=O)C2CCC2C(=O)O)sc1C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I14 compound treatment 0.431 0.202 2.12 0.415 0.185 2.21 3.0634 0.9998 1616395 Maybridge4_001246 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc(F)cc2F)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I15 compound treatment 0.421 0.192 2.01 0.445 0.215 2.57 3.2429 0.9927 1670393 Maybridge4_001247 Cc1oc(cc1c2nc(no2)c3ccc(cc3)C(C)(C)C)S(=O)(=O)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I16 compound treatment 0.599 0.37 3.88 0.542 0.312 3.73 5.3855 0.9998 1316867 Maybridge4_001248 CC(C)(C)c1ccc(cc1)c2nnc(SCc3cccc(c3)C(=O)N)n2c4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I17 compound treatment 0.146 -0.0832 -0.87 0.158 -0.072 -0.86 -1.2274 -1.0 1620610 Maybridge4_001249 OC(CNCc1ccc2OCOc2c1)COc3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I18 compound treatment 0.228 -0.00122 -0.01 0.224 -0.00603 -0.07 -0.0601 -0.8197 1465779 Maybridge4_001250 CC(=O)Nc1cccc(c1)n2nnc(SCC(=O)c3ccccc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I19 compound treatment 0.239 0.00978 0.1 0.263 0.033 0.39 0.3516 0.8625 1598604 Maybridge4_001251 Cn1nc(NC(=O)CC(C)(C)CC(=O)O)c2c(F)cccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I20 compound treatment 0.291 0.0618 0.65 0.306 0.076 0.91 1.1015 0.9864 1238878 Maybridge4_001252 Cc1oc(cc1C(=O)Nc2ccccc2)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I21 compound treatment 0.305 0.0758 0.8 0.259 0.029 0.35 0.8079 0.9306 1457140 Maybridge4_001253 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I22 compound treatment 0.333 0.104 1.09 0.316 0.086 1.03 1.498 0.9996 1519073 Maybridge4_001254 O=S(=O)(NCC1CCN(CC1)S(=O)(=O)c2ccccc2)c3cccc4nonc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I23 mock treatment 0.192 -0.0372 -0.39 0.258 0.028 0.33 -0.0398 -0.0773 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 I24 mock treatment 0.234 0.00478 0.05 0.252 0.022 0.26 0.2214 0.8272 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J01 compound treatment 0.199 -0.0302 -0.32 0.178 -0.052 -0.62 -0.6646 -0.9511 1542762 Maybridge4_001255 OC(=O)c1nccnc1C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J02 compound treatment 0.319 0.0898 0.94 0.318 0.088 1.05 1.411 0.9985 1359019 Maybridge4_001256 CCCc1cnc(nc1)N2CCN(CC2)C(=S)NC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J03 compound treatment 0.731 0.502 5.27 0.721 0.491 5.87 7.8801 0.9985 1448044 Maybridge4_001257 CC(C)n1c(SCC(=O)c2ccccc2)nc3cc(Cl)ccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J04 compound treatment 0.222 -0.00722 -0.08 0.216 -0.014 -0.17 -0.1723 -0.9355 1537193 Maybridge4_001258 CCS(=O)(=O)c1ccc(O)c(NC(=O)CCCC(=O)O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J05 compound treatment 0.25 0.0208 0.22 0.242 0.012 0.14 0.2556 0.9791 1258625 Maybridge4_001259 Cc1oc(cc1C(=O)NCCN2CCNC2=O)S(=O)(=O)N3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J06 compound treatment 0.089 -0.14 -1.47 0.106 -0.124 -1.48 -2.0907 -1.0 1248986 Maybridge4_001260 Cc1ccc2n(CC(=O)c3ccccc3)c(=O)oc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J07 compound treatment 0.241 0.0118 0.12 0.226 -0.00403 -0.05 0.0534 0.4019 1612362 Maybridge4_001261 OC(=O)COCC(=O)Nc1ccc2COC(=O)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J08 compound treatment 0.188 -0.0412 -0.43 0.173 -0.057 -0.68 -0.7886 -0.9759 1623545 Maybridge4_001262 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)COCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J09 compound treatment 0.168 -0.0612 -0.64 0.174 -0.056 -0.67 -0.9287 -0.9998 3063556 Maybridge4_001263 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)NC3CCCCC3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J10 compound treatment 0.302 0.0728 0.76 0.276 0.046 0.55 0.9294 0.987 3178332 Maybridge4_001264 O=C(CSc1nccc(n1)c2cccs2)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J11 compound treatment 0.617 0.388 4.07 0.616 0.386 4.62 6.1452 0.998 3178333 Maybridge4_001265 Clc1cc(ccc1NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J12 compound treatment 0.216 -0.0132 -0.14 0.201 -0.029 -0.35 -0.3438 -0.919 3063557 Maybridge4_001266 Cc1csc(NC(=O)c2ccccc2C(=O)O)c1c3nc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J13 compound treatment 0.227 -0.00222 -0.02 0.236 0.00597 0.07 0.034 0.4528 3178334 Maybridge4_001267 Fc1cc(CNC(=O)c2ccc3nonc3c2)c4OCOCc4c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J14 compound treatment 0.084 -0.145 -1.53 0.088 -0.142 -1.7 -2.2801 -0.9985 1272012 Maybridge4_001268 C1COc2cc(ccc2O1)c3cn4cccnc4n3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J15 compound treatment 0.229 -2.19E-4 0.0 0.191 -0.039 -0.47 -0.3318 -0.7106 1207844 Maybridge4_001269 Cc1ccc(cc1)c2csc3ncnc(NCCN4CCNC4=O)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J16 compound treatment 0.221 -0.00822 -0.09 0.227 -0.00303 -0.04 -0.0867 -0.9258 3063558 Maybridge4_001270 OC(=O)COCC(=O)Nc1cccc(c1)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J17 compound treatment 0.289 0.0598 0.63 0.24 0.00997 0.12 0.5283 0.8266 1592295 Maybridge4_001271 Cn1nc(c(NC(=O)c2ccc(F)cc2)c1C(C)(C)C)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J18 compound treatment 0.483 0.254 2.67 0.477 0.247 2.95 3.9741 0.9987 1672779 Maybridge4_001272 O=C(Nc1ccccc1)Nc2ccc(C#N)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J19 compound treatment 0.241 0.0118 0.12 0.191 -0.039 -0.47 -0.2427 -0.5024 1287020 Maybridge4_001273 Nc1nccc(n1)c2nn(ccc2=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J20 compound treatment 0.239 0.00978 0.1 0.193 -0.037 -0.44 -0.2407 -0.5291 1290569 Maybridge4_001274 CCOC(=O)N1CCC(CC1)NC(=O)c2ccccc2C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J21 compound treatment 0.224 -0.00522 -0.05 0.228 -0.00203 -0.02 -0.056 -0.9331 1226002 Maybridge4_001275 Cc1nn(C)cc1NC(=O)Nc2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J22 compound treatment 0.364 0.135 1.42 0.374 0.144 1.72 2.2189 0.9953 3178335 Maybridge4_001276 O=C(Nc1ccccc1)N(CCC#N)Cc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J23 mock treatment 0.278 0.0488 0.51 0.232 0.00197 0.02 0.3789 0.7388 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 J24 mock treatment 0.223 -0.00622 -0.07 0.251 0.021 0.25 0.1312 0.5061 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K01 compound treatment 0.145 -0.0842 -0.88 0.131 -0.099 -1.18 -1.4633 -0.9896 1539150 Maybridge4_001277 CC(C)(C)c1cc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K02 compound treatment 0.471 0.242 2.54 0.509 0.279 3.34 4.1557 0.9909 1563937 Maybridge4_001278 COC(=O)c1c(C)oc(C)c1S(=O)(=O)Nc2ccc(cc2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K03 compound treatment 0.801 0.572 6.01 0.831 0.601 7.19 9.3306 0.996 3063559 Maybridge4_001279 CCC1CSc2nc3ccsc3c(=O)n12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K04 compound treatment 0.365 0.136 1.43 0.352 0.122 1.46 2.0402 0.9999 3178336 Maybridge4_001280 FC(F)(F)c1cccc(c1)N2CCN(CC2)C3=Cc4ccccc4CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K05 compound treatment 0.294 0.0648 0.68 0.259 0.029 0.35 0.7262 0.951 3063560 Maybridge4_001281 FC(F)(F)c1ccnc(S)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K06 compound treatment 0.266 0.0368 0.39 0.26 0.03 0.36 0.5267 0.9993 3178337 Maybridge4_001282 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccc(cc2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K07 compound treatment 0.738 0.509 5.34 0.728 0.498 5.96 7.9913 0.9985 1176274 Maybridge4_001283 CC1CC(CC(C)(C)C1)NC(=S)NC2CC3CC2C=C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K08 compound treatment 0.949 0.72 7.56 0.954 0.724 8.66 11.4703 0.9977 1427567 Maybridge4_001284 Cc1ccc(C)n1c2ccc(cc2)C3(O)CCSc4ccccc43 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K09 compound treatment 0.653 0.424 4.45 0.605 0.375 4.49 6.3195 1.0 1358302 Maybridge4_001285 CC(C)(C)OC(=O)N1CCC(CC1)c2nc(cs2)c3ccc(Cl)s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K10 compound treatment 0.243 0.0138 0.14 0.265 0.035 0.42 0.3982 0.8994 1583408 Maybridge4_001286 COc1ccccc1CCNS(=O)(=O)c2ccc(C(=O)O)n2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K11 compound treatment 0.297 0.0678 0.71 0.276 0.046 0.55 0.8923 0.9919 3178338 Maybridge4_001287 OC1(CCN(CC1)C(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K12 compound treatment 0.182 -0.0472 -0.5 0.199 -0.031 -0.37 -0.6132 -0.9898 3063561 Maybridge4_001288 OC1(NC(=O)c2cnn(c2C(F)(F)F)c3ccccc3)C(=O)c4ccccc4C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K13 compound treatment 1.484 1.25 13.18 1.618 1.39 16.61 21.061 0.9934 3178339 Maybridge4_001289 COc1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1OC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K14 compound treatment 0.445 0.216 2.27 0.358 0.128 1.53 2.6851 0.9818 1513815 Maybridge4_001290 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc3cccnc23)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K15 compound treatment 0.401 0.172 1.8 0.388 0.158 1.89 2.6122 0.9997 1269818 Maybridge4_001291 Cc1cc(NS(=O)(=O)c2ccc(NCN3C(=O)c4ccccc4C3=O)cc2)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K16 compound treatment 0.361 0.132 1.38 0.345 0.115 1.38 1.9513 1.0 3178340 Maybridge4_001292 CC(C)NC(=O)CSc1nnc(c2ccc(cc2)C(C)(C)C)n1c3ccc4OCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K17 compound treatment 0.218 -0.0112 -0.12 0.185 -0.045 -0.54 -0.4643 -0.8418 1222771 Maybridge4_001293 NC(=O)C1CCN(CC(O)COc2ccc(F)cc2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K18 compound treatment 0.559 0.33 3.46 0.55 0.32 3.83 5.1561 0.9988 1223041 Maybridge4_001294 CC(=O)Nc1cccc(c1)n2nnc(SCc3cc(Cl)cc4COCOc34)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K19 compound treatment 0.286 0.0568 0.6 0.264 0.034 0.41 0.7091 0.9825 1546521 Maybridge4_001295 COc1ccc2[nH]c(cc2c1)C(=O)N3CCC(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K20 compound treatment 0.33 0.101 1.06 0.307 0.077 0.92 1.3996 0.9976 1729108 Maybridge4_001296 Cc1oc(cc1c2nc(no2)c3ccc(F)cc3)S(=O)(=O)N4CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K21 compound treatment 0.53 0.301 3.16 0.498 0.268 3.21 4.5008 1.0 3178447 Maybridge4_001297 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4cccc(c4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K22 compound treatment 0.478 0.249 2.61 0.537 0.307 3.67 4.4446 0.9861 1411945 Maybridge4_001298 Cc1ccc(Oc2ncccc2NS(=O)(=O)c3ccc(s3)c4ccccn4)c5CCCc51 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K23 mock treatment 0.201 -0.0282 -0.3 0.229 -0.00103 -0.01 -0.2183 -0.7359 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 K24 mock treatment 0.271 0.0418 0.44 0.253 0.023 0.27 0.5046 0.9746 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L01 compound treatment 0.188 -0.0412 -0.43 0.204 -0.026 -0.31 -0.5263 -0.987 3178448 Maybridge4_001299 COCc1cc(O)nc(SCC(=O)c2ccccc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L02 compound treatment 0.257 0.0278 0.29 0.255 0.025 0.3 0.4175 0.9999 3063562 Maybridge4_001300 Fc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)c3nccc(n3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L03 compound treatment 0.23 7.81E-4 0.01 0.136 -0.094 -1.13 -0.7897 -0.7019 3178449 Maybridge4_001301 Nc1nc(SCC(=O)c2cc(no2)c3ccccc3)ncc1C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L04 compound treatment 0.27 0.0408 0.43 0.203 -0.027 -0.32 0.0742 0.1382 1497829 Maybridge4_001302 CCCNC(=O)Nc1cc(ccc1O)S(=O)(=O)CC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L05 compound treatment 0.269 0.0398 0.42 0.274 0.044 0.53 0.6674 0.9935 1614464 Maybridge4_001303 OC(CN(CCN1CCNC1=O)CC(O)c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L06 compound treatment 0.5 0.271 2.84 0.512 0.282 3.37 4.3964 0.9964 1416766 Maybridge4_001304 Clc1ccc2scc(CNS(=O)(=O)c3cc(cs3)S(=O)(=O)c4ccccc4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L07 compound treatment 0.239 0.00978 0.1 0.199 -0.031 -0.37 -0.1899 -0.4929 3063563 Maybridge4_001305 O=C(Nc1ccc2COC(=O)c2c1)c3cc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L08 compound treatment 0.198 -0.0312 -0.33 0.191 -0.039 -0.47 -0.5621 -0.985 3178450 Maybridge4_001306 Cc1cc(NC(=O)NCCNc2ncccc2C(F)(F)F)c(o1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L09 compound treatment 0.229 -2.19E-4 0.0 0.201 -0.029 -0.35 -0.2472 -0.7118 3178451 Maybridge4_001307 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3cccs3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L10 compound treatment 0.31 0.0808 0.85 0.262 0.032 0.38 0.8704 0.9352 3063564 Maybridge4_001308 O=C(CSc1nccc(n1)c2cccs2)N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L11 compound treatment 0.096 -0.133 -1.4 0.087 -0.143 -1.71 -2.1994 -0.995 1340769 Maybridge4_001309 Cc1c(csc1C(=O)NC2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L12 compound treatment 0.273 0.0438 0.46 0.208 -0.022 -0.26 0.1387 0.2618 1452839 Maybridge4_001310 Clc1cccc(Oc2ccccc2)c1CNC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L13 compound treatment 0.225 -0.00422 -0.04 0.205 -0.025 -0.3 -0.2431 -0.803 1545947 Maybridge4_001311 Cc1ccc(cc1)S(=O)(=O)NC(=O)OCCn2ncc3ccccc3c2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L14 compound treatment 0.231 0.00178 0.02 0.175 -0.055 -0.66 -0.4524 -0.6867 1335669 Maybridge4_001312 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NCC3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L15 compound treatment 0.198 -0.0312 -0.33 0.217 -0.013 -0.16 -0.3421 -0.9423 1301958 Maybridge4_001313 O=C1NCCN1CCNc2cccc(C#N)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L16 compound treatment 0.194 -0.0352 -0.37 0.245 0.015 0.18 -0.1349 -0.3283 1237826 Maybridge4_001314 OC(=O)c1cccc(NC(=O)c2nccnc2C(=O)O)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L17 compound treatment 0.263 0.0338 0.35 0.229 -0.00103 -0.01 0.2421 0.6821 1167798 Maybridge4_001315 CCOC(=O)C1CCN(CC1)c2ccccc2CN3CCCc4cc(C)ccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L18 compound treatment 0.25 0.0208 0.22 0.204 -0.026 -0.31 -0.0659 -0.1733 1532681 Maybridge4_001316 O=C(NCC1CC1)c2ccccc2NS(=O)(=O)c3cccc4nonc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L19 compound treatment 0.231 0.00178 0.02 0.23 -3.23E-5 0.0 0.013 0.6924 3178452 Maybridge4_001317 COc1ccc(OCCNC(=O)c2nccnc2C(=O)O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L20 compound treatment 0.275 0.0458 0.48 0.28 0.05 0.6 0.7627 0.9942 3063588 Maybridge4_001318 OC(=O)COCC(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L21 compound treatment 0.254 0.0248 0.26 0.217 -0.013 -0.16 0.0738 0.2432 1125657 Maybridge4_001319 NC(=O)C1CCN(CC1)C(=O)Nc2cc3ccccc3s2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L22 compound treatment 0.536 0.307 3.22 0.596 0.366 4.38 5.3745 0.9886 3063589 Maybridge4_001320 Cc1ccc(cc1)S(=O)(=O)CCSCc2csc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L23 mock treatment 0.252 0.0228 0.24 0.234 0.00397 0.05 0.2028 0.8312 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 L24 mock treatment 0.275 0.0458 0.48 0.227 -0.00303 -0.04 0.3143 0.6519 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M01 compound treatment 1.34 1.11 11.67 1.312 1.08 12.95 17.4028 0.9987 1132483 Maybridge4_001321 N(c1ccccc1)c2ncnc3cc(sc23)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M02 compound treatment 0.233 0.00378 0.04 0.24 0.00997 0.12 0.1124 0.8943 1732345 Maybridge4_001322 OC(=O)CSCC(=O)N1CCN(CC1)S(=O)(=O)c2cc(Cl)cc(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M03 compound treatment 0.235 0.00578 0.06 0.188 -0.042 -0.5 -0.3127 -0.6172 1627433 Maybridge4_001323 NCCNC(=O)Cc1ccc(O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M04 compound treatment 0.408 0.179 1.88 0.403 0.173 2.07 2.7911 0.9988 1237825 Maybridge4_001324 O=C(Nc1nc2ccccc2c(=O)s1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M05 compound treatment 0.35 0.121 1.27 0.409 0.179 2.14 2.4111 0.9688 1700739 Maybridge4_001325 OC(CSc1cccs1)CSc2ccccc2NC(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M06 compound treatment 0.412 0.183 1.92 0.465 0.235 2.81 3.3453 0.9827 1271443 Maybridge4_001326 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccsc2C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M07 compound treatment 0.781 0.552 5.8 0.759 0.529 6.33 8.5729 0.999 3063590 Maybridge4_001327 S=C(NC(Cc1ccccc1)c2ccccc2)NC3CC4CC3C=C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M08 compound treatment 0.302 0.0728 0.76 0.316 0.086 1.03 1.2678 0.9893 1434508 Maybridge4_001328 Fc1ccc2[nH]cc(CCCN3CCN(CC3)c4nc5cc(Cl)ccc5s4)c2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M09 compound treatment 0.604 0.375 3.94 0.586 0.356 4.26 5.7949 0.9992 1293074 Maybridge4_001329 COC(=O)c1cc(oc1C)S(=O)(=O)Nc2nn(C)c3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M10 compound treatment 0.172 -0.0572 -0.6 0.172 -0.058 -0.69 -0.9159 -0.9974 1681613 Maybridge4_001330 O=C(NCc1ccc2OCOc2c1)c3cc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M11 compound treatment 0.265 0.0358 0.38 0.315 0.085 1.02 0.9846 0.9084 1565655 Maybridge4_001331 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M12 compound treatment 0.219 -0.0102 -0.11 0.216 -0.014 -0.17 -0.1946 -0.9766 1050571 Maybridge4_001332 OC(=O)CCc1cccnc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M13 compound treatment 1.369 1.14 11.97 1.383 1.15 13.79 18.2189 0.9975 1126449 Maybridge4_001333 COc1ccc(NC(=O)C2CCCCC2)cc1OC3CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M14 compound treatment 0.4 0.171 1.79 0.451 0.221 2.64 3.1377 0.9821 1537113 Maybridge4_001334 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2ccc3OCCOc3c2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M15 compound treatment 0.218 -0.0112 -0.12 0.191 -0.039 -0.47 -0.4135 -0.8586 1458162 Maybridge4_001335 CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)N3C(=O)CSCC3=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M16 compound treatment 0.074 -0.155 -1.63 0.057 -0.173 -2.07 -2.6166 -0.993 1342126 Maybridge4_001336 NC(=O)NC(=O)Cc1nc2ccccc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M17 compound treatment 0.151 -0.0782 -0.82 0.156 -0.074 -0.89 -1.2072 -0.9993 1668027 Maybridge4_001337 OC(CNC1Cc2ccccc2C1)COc3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M18 compound treatment 0.215 -0.0142 -0.15 0.198 -0.032 -0.38 -0.3766 -0.9156 3063591 Maybridge4_001338 OC(=O)CSc1nc2cccnc2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M19 compound treatment 0.269 0.0398 0.42 0.237 0.00697 0.08 0.3544 0.8318 1290479 Maybridge4_001339 NC(=O)C1CCN(CC(O)COc2ccc3OCOc3c2)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M20 compound treatment 0.369 0.14 1.47 0.277 0.047 0.56 1.4354 0.9132 1132021 Maybridge4_001340 COC(=O)c1scc(C)c1NS(=O)(=O)c2ccc3OCCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M21 compound treatment 0.595 0.366 3.84 0.592 0.362 4.33 5.7788 0.9982 1157417 Maybridge4_001341 COc1ccc(cc1OC)S(=O)(=O)n2nc(n3c(C)ccc3C)c4c(F)cccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M22 compound treatment 0.197 -0.0322 -0.34 0.257 0.027 0.32 -0.0111 -0.0238 1722963 Maybridge4_001342 Cc1nc(cn1C)S(=O)(=O)N2CCC(CC2)NC(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M23 mock treatment 0.242 0.0128 0.13 0.209 -0.021 -0.25 -0.083 -0.2911 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 M24 mock treatment 0.215 -0.0142 -0.15 0.235 0.00497 0.06 -0.0636 -0.3955 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N01 compound treatment 0.186 -0.0432 -0.45 0.188 -0.042 -0.5 -0.6766 -0.9987 1329289 Maybridge4_001343 OC(=O)c1ccccc1C(=O)NCCN2CCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N02 compound treatment 0.264 0.0348 0.37 0.239 0.00897 0.11 0.3342 0.8777 3178453 Maybridge4_001344 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)S(=O)(=O)c3cccc4nonc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N03 compound treatment 0.354 0.125 1.31 0.392 0.162 1.94 2.297 0.9819 1118431 Maybridge4_001345 CCOC(=O)c1cc(NC(=O)CC(C)(C)CC(=O)O)ccc1N2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N04 compound treatment 0.292 0.0628 0.66 0.266 0.036 0.43 0.7705 0.9786 1615128 Maybridge4_001346 CCS(=O)(=O)c1ccc(O)c(NC(=O)Nc2ccccc2OC)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N05 compound treatment 0.28 0.0508 0.53 0.23 -3.23E-5 0.0 0.3769 0.7066 3178454 Maybridge4_001347 Cc1nc(cn1C)S(=O)(=O)NCCNc2ccc(nn2)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N06 compound treatment 0.303 0.0738 0.77 0.261 0.031 0.37 0.8099 0.943 3063592 Maybridge4_001348 FC(F)(F)c1ccc(cc1)S(=O)(=O)Nc2ccc3COC(=O)c3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N07 compound treatment 0.933 0.704 7.39 0.866 0.636 7.61 10.607 0.9999 1059288 Maybridge4_001349 O=C1NC(Nc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N08 compound treatment 0.099 -0.13 -1.37 0.134 -0.096 -1.15 -1.7795 -0.9962 3063593 Maybridge4_001350 Cc1cc(NC(=O)Nc2ccccc2)c(o1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N09 compound treatment 0.267 0.0378 0.4 0.271 0.041 0.49 0.6272 0.9945 3178455 Maybridge4_001351 COc1cccc(c1)C(=O)NCCN2CCN(CC2)c3nccc(n3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N10 compound treatment 0.213 -0.0162 -0.17 0.235 0.00497 0.06 -0.0784 -0.4347 1126742 Maybridge4_001352 Cc1cc(NC(=O)CCCC(=O)O)n(C)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N11 compound treatment 0.616 0.387 4.06 0.604 0.374 4.47 6.0363 0.9988 1374549 Maybridge4_001353 COc1ccccc1C2CCN(CC2)C(=O)c3scc(c3C)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N12 compound treatment 0.196 -0.0332 -0.35 0.233 0.00297 0.04 -0.2216 -0.6319 1540730 Maybridge4_001354 Cc1oc(cc1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N13 compound treatment 0.342 0.113 1.18 0.339 0.109 1.3 1.7595 0.9989 1417640 Maybridge4_001355 O=C(Nc1cccc2ccccc12)OCCn3ncc4ccccc4c3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N14 compound treatment 0.329 0.0998 1.05 0.268 0.038 0.45 1.0622 0.93 1318344 Maybridge4_001356 COC(=O)c1sccc1S(=O)(=O)Nc2ccc3OCCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N15 compound treatment 0.272 0.0428 0.45 0.273 0.043 0.51 0.6812 0.9977 3178549 Maybridge4_001357 FC(F)(F)Oc1ccc(NC(=S)NCCN2CCNC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N16 compound treatment 0.337 0.108 1.13 0.269 0.039 0.47 1.1301 0.9231 1460315 Maybridge4_001358 COc1ccc(OCC(O)CNC(=O)c2cc(nn2C)C(C)(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N17 compound treatment 0.092 -0.137 -1.44 0.102 -0.128 -1.53 -2.1022 -0.9995 1196797 Maybridge4_001359 CCCc1c(cnn1c2ccccc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N18 compound treatment 0.268 0.0388 0.41 0.243 0.013 0.16 0.3977 0.9125 3178550 Maybridge4_001360 COc1cc(OCc2ccccc2)ccc1CN3CCN(CC3)c4ccc(cn4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N19 compound treatment 0.253 0.0238 0.25 0.379 0.149 1.78 1.4369 0.7984 1300856 Maybridge4_001361 O=C(NC1Cc2ccccc2C1)Nc3cc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N20 compound treatment 0.261 0.0318 0.33 0.244 0.014 0.17 0.3542 0.9489 1617412 Maybridge4_001362 OC(=O)CC(CC(=O)N1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N21 compound treatment 0.279 0.0498 0.52 0.3 0.07 0.84 0.9616 0.9743 1534103 Maybridge4_001363 OC(COc1ccc(cc1)c2csnn2)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N22 compound treatment 0.496 0.267 2.8 0.476 0.246 2.94 4.0622 0.9997 3063594 Maybridge4_001364 Clc1ccc(c(Cl)c1)S(=O)(=O)CCSCc2csc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N23 mock treatment 0.301 0.0718 0.75 0.265 0.035 0.42 0.8289 0.9614 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 N24 mock treatment 0.23 7.81E-4 0.01 0.242 0.012 0.14 0.1071 0.7464 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O01 compound treatment 0.16 -0.0692 -0.73 0.166 -0.064 -0.77 -1.0558 -0.9997 1379542 Maybridge4_001365 CC(C)(C)c1cc2ncnc(N3CCCCC3)c2s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O02 compound treatment 0.265 0.0358 0.38 0.258 0.028 0.33 0.5023 0.9983 1268570 Maybridge4_001366 Cc1cc(OCC(=O)N(C2CCCCC2)c3ccccc3)c4ccccc4n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O03 compound treatment 0.139 -0.0902 -0.95 0.124 -0.106 -1.27 -1.5671 -0.9897 3063595 Maybridge4_001367 FC(F)(F)c1ccn(n1)S(=O)(=O)c2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O04 compound treatment 0.281 0.0518 0.54 0.331 0.101 1.21 1.2388 0.9351 1471781 Maybridge4_001368 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O05 compound treatment 0.208 -0.0212 -0.22 0.221 -0.00903 -0.11 -0.234 -0.9448 3178551 Maybridge4_001369 COC(=O)c1cn(Cc2ccc(Cl)cc2)cc(F)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O06 compound treatment 0.158 -0.0712 -0.75 0.165 -0.065 -0.78 -1.0791 -0.9998 1122209 Maybridge4_001370 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCCN(Cc3ccccc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O07 compound treatment 0.488 0.259 2.72 0.447 0.217 2.6 3.7574 0.9997 1177633 Maybridge4_001371 CC(C)(CCO)NC(=S)NC1CC2CC1C=C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O08 compound treatment 0.369 0.14 1.47 0.342 0.112 1.34 1.9853 0.999 1162225 Maybridge4_001372 CCNC(=O)c1c(C)onc1c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O09 compound treatment 0.216 -0.0132 -0.14 0.21 -0.02 -0.24 -0.2676 -0.9663 3063596 Maybridge4_001373 Cc1csc2c(NCCCN3CCOCC3)ncnc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O10 compound treatment 0.53 0.301 3.16 0.498 0.268 3.21 4.5008 1.0 3178552 Maybridge4_001374 COc1ccc(cc1)c2cc(C(=O)Nc3ccc(F)cc3)c(o2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O11 compound treatment 0.194 -0.0352 -0.37 0.225 -0.00503 -0.06 -0.3041 -0.8115 3063597 Maybridge4_001375 Fc1ccc(cc1)S(=O)(=O)N2CCN=C(C=C2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O12 compound treatment 0.612 0.383 4.02 0.642 0.412 4.93 6.328 0.9949 1566889 Maybridge4_001376 O=C(Nc1ccc2OCCOc2c1)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O13 compound treatment 0.226 -0.00322 -0.03 0.257 0.027 0.32 0.2042 0.6296 3178553 Maybridge4_001377 CC(=O)Nc1c(c(nn1C)C(F)(F)F)c2cccc(c2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O14 compound treatment 0.297 0.0678 0.71 0.263 0.033 0.39 0.7823 0.9612 1314147 Maybridge4_001378 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cc(Cl)sc2Cl)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O15 compound treatment 0.218 -0.0112 -0.12 0.2 -0.03 -0.36 -0.3374 -0.8922 1617882 Maybridge4_001379 OC(=O)CC1(CC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)CCCC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O16 compound treatment 0.06 -0.169 -1.78 0.294 0.064 0.77 -0.7155 -0.3698 3063620 Maybridge4_001380 Cc1nc(nc(SCC(=O)c2ccc(F)cc2)c1Cl)c3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O17 compound treatment 0.174 -0.0552 -0.58 0.184 -0.046 -0.55 -0.7995 -0.9997 1499688 Maybridge4_001381 NC(=O)C1CCN(Cn2nnc3ccccc23)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O18 compound treatment 1.242 1.01 10.64 1.214 0.984 11.77 15.8459 0.9987 1432924 Maybridge4_001382 COc1ccc(CCNC(=O)c2cc3ccccc3s2)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O19 compound treatment 0.247 0.0178 0.19 0.301 0.071 0.85 0.7325 0.8425 1075902 Maybridge4_001383 COc1ccccc1NC(=O)Nc2ccccc2OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O20 compound treatment 0.125 -0.104 -1.09 0.123 -0.107 -1.28 -1.6795 -0.9969 3063621 Maybridge4_001384 Fc1ccc(cc1)S(=O)(=O)CCN2CCN=C(C=C2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O21 compound treatment 0.316 0.0868 0.91 0.31 0.08 0.96 1.321 0.9997 1600262 Maybridge4_001385 O=C(CC1(CC2CC3CC(C2)C1)C3)NCc4ccc5OCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O22 compound treatment 0.326 0.0968 1.02 0.289 0.059 0.71 1.2176 0.9841 1226207 Maybridge4_001386 OC(=O)CCn1nc(ccc1=O)c2ccc(F)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O23 mock treatment 0.217 -0.0122 -0.13 0.24 0.00997 0.12 -0.0064 -0.0366 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 O24 mock treatment 0.259 0.0298 0.31 0.271 0.041 0.49 0.5678 0.9765 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P01 compound treatment 0.234 0.00478 0.05 0.197 -0.033 -0.4 -0.2439 -0.6123 1550189 Maybridge4_001387 Cc1ccc(cc1)C(=O)NCCN2CCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P02 compound treatment 0.653 0.424 4.45 0.641 0.411 4.92 6.6241 0.9988 3178554 Maybridge4_001388 Cc1ccsc1CNC(=O)Nc2ccc(cc2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P03 compound treatment 0.447 0.218 2.29 0.458 0.228 2.73 3.546 0.9962 3063622 Maybridge4_001389 CCOC(=O)C(C#N)C1C(=C(N)Oc2c(C)cc(Cl)cc12)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P04 compound treatment 0.918 0.689 7.23 0.977 0.747 8.94 11.4347 0.9945 1160881 Maybridge4_001390 COC(=O)c1sccc1c2ccc(CN3CCCc4cc(OC)ccc34)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P05 compound treatment 0.233 0.00378 0.04 0.222 -0.00803 -0.1 -0.0399 -0.3835 1537339 Maybridge4_001391 COC(=O)c1sccc1S(=O)(=O)NC2CCS(=O)(=O)C2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P06 compound treatment 0.258 0.0288 0.3 0.209 -0.021 -0.25 0.0358 0.091 3178555 Maybridge4_001392 O=C1OCc2ccc(NS(=O)(=O)c3ccccc3C#N)cc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P07 compound treatment 0.167 -0.0622 -0.65 0.18 -0.05 -0.6 -0.8853 -0.999 1343805 Maybridge4_001393 O=C(NC1CCN(Cc2ccccc2)CC1)Nc3cc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P08 compound treatment 0.079 -0.15 -1.58 0.087 -0.143 -1.71 -2.3257 -0.9992 3063623 Maybridge4_001394 Cc1cc(NC(=O)NCc2ccccc2)c(o1)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P09 compound treatment 0.195 -0.0342 -0.36 0.166 -0.064 -0.77 -0.7958 -0.9405 3178556 Maybridge4_001395 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3ccc(Cl)cc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P10 compound treatment 0.29 0.0608 0.64 0.336 0.106 1.27 1.3479 0.9496 1315475 Maybridge4_001396 Cc1oc(cc1C(=O)NCc2csc3ccc(Cl)cc23)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P11 compound treatment 0.512 0.283 2.97 0.489 0.259 3.1 4.291 0.9998 1707754 Maybridge4_001397 Cc1c(csc1C(=O)N2CCCc3cc(C)ccc23)S(=O)(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P12 compound treatment 0.288 0.0588 0.62 0.273 0.043 0.51 0.8001 0.9959 1437749 Maybridge4_001398 CC(C)c1ccc(NC(=O)c2cc(oc2C)C(C)(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P13 compound treatment 0.517 0.288 3.02 0.523 0.293 3.51 4.6158 0.9973 3178557 Maybridge4_001399 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)c3cccs3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P14 compound treatment 0.214 -0.0152 -0.16 0.205 -0.025 -0.3 -0.3248 -0.9568 1200741 Maybridge4_001400 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2ncccc2C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P15 compound treatment 0.336 0.107 1.12 0.442 0.212 2.54 2.5863 0.9327 1650074 Maybridge4_001401 CCOC(=O)c1ccc(NC(=S)NCCN2CCNC2=O)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P16 compound treatment 0.653 0.424 4.45 0.616 0.386 4.62 6.4126 0.9998 1225431 Maybridge4_001402 COc1ccc(OCC(O)CNC(=O)c2cccnc2Oc3ccc(Cl)cc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P17 compound treatment 0.493 0.264 2.77 0.495 0.265 3.17 4.2006 0.9977 1670405 Maybridge4_001403 CCCc1c(cnn1c2ccccc2)C(=O)NC3Cc4ccccc4C3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P18 compound treatment 0.233 0.00378 0.04 0.221 -0.00903 -0.11 -0.0483 -0.4198 1600703 Maybridge4_001404 COc1cc(OCc2ccccc2)ccc1CN3CCC(CC3)C(=O)c4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P19 compound treatment 1.403 1.17 12.33 1.412 1.18 14.14 18.7167 0.9977 1497768 Maybridge4_001405 Fc1ccc(NC(=O)Nc2cc3ccccc3s2)c(F)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P20 compound treatment 0.257 0.0278 0.29 0.222 -0.00803 -0.1 0.1384 0.4504 1490941 Maybridge4_001406 Cc1nnsc1C(=O)NCc2c(Cl)cccc2Sc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P21 compound treatment 0.173 -0.0562 -0.59 0.22 -0.01 -0.12 -0.5024 -0.8338 1271550 Maybridge4_001407 OC(CNCc1ccc2OCOc2c1)COc3ccc(cc3)c4csnn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P22 compound treatment 0.244 0.0148 0.16 0.277 0.047 0.56 0.5071 0.8699 3063624 Maybridge4_001408 CC1(C)CCc2cc(CN3CCN(CC3)c4ncc(cc4Cl)C(F)(F)F)ccc2O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P23 mock treatment 0.237 0.00778 0.08 0.353 0.123 1.47 1.0981 0.7452 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2052 P24 mock treatment 0.252 0.0228 0.24 0.248 0.018 0.21 0.3212 0.9986 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A01 compound treatment 0.183 -0.0522 -0.55 0.222 -0.0123 -0.15 -0.4917 -0.8664 1291502 Maybridge4_001409 Fc1ccc(cc1)c2n[nH]cc2CN3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A02 compound treatment 0.297 0.0618 0.65 0.277 0.0427 0.51 0.8202 0.993 1286225 Maybridge4_001410 O=C(NC1CCN(CC1)C(=O)OCc2ccccc2)Nc3ccccc3N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A03 compound treatment 0.194 -0.0412 -0.43 0.226 -0.00831 -0.1 -0.3762 -0.8476 1251898 Maybridge4_001411 Cc1cc(C)c(SCC(=O)NCc2ccc3OCOc3c2)c(C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A04 compound treatment 0.188 -0.0472 -0.5 0.244 0.00969 0.12 -0.2685 -0.5275 1262294 Maybridge4_001412 CCCCN1Cc2c([nH]c3cc(nn3c2=O)C(C)(C)C)C1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A05 compound treatment 0.184 -0.0512 -0.54 0.177 -0.0573 -0.69 -0.865 -0.9928 1594634 Maybridge4_001413 OC(=O)CCCC(=O)NC1CCCc2ccccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A06 compound treatment 0.262 0.0268 0.28 0.285 0.0507 0.61 0.6279 0.9391 3178643 Maybridge4_001414 COc1cc2CCN(Cc3sc4ccccc4c3C)C(C)c2cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A07 compound treatment 0.168 -0.0672 -0.71 0.175 -0.0593 -0.71 -1.0008 -1.0 1319283 Maybridge4_001415 OC(CNC(=O)Nc1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A08 compound treatment 0.15 -0.0852 -0.89 0.158 -0.0763 -0.91 -1.2783 -0.9999 1715585 Maybridge4_001416 Cc1cccc(NC(=O)c2ccco2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A09 compound treatment 0.172 -0.0632 -0.66 0.167 -0.0673 -0.81 -1.0387 -0.9954 1554836 Maybridge4_001417 CCCc1cnc(nc1)N2CCN(CC2)S(=O)(=O)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A10 compound treatment 0.536 0.301 3.16 0.493 0.259 3.1 4.4225 0.9999 3178644 Maybridge4_001418 O=S(=O)(Nc1ccccc1N2CCOCC2)c3ccc(s3)c4ccccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A11 compound treatment 1.08 0.845 8.87 0.896 0.662 7.92 11.872 0.9984 3178645 Maybridge4_001419 Cc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A12 compound treatment 0.15 -0.0852 -0.89 0.157 -0.0773 -0.93 -1.2867 -0.9999 3063626 Maybridge4_001420 Oc1nnc(S)n1C2CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A13 compound treatment 0.183 -0.0522 -0.55 0.177 -0.0573 -0.69 -0.8724 -0.9938 3178646 Maybridge4_001421 CN(C(=O)c1c(C)onc1c2c(Cl)cccc2Cl)c3nnc(s3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A14 compound treatment 0.303 0.0678 0.71 0.324 0.0897 1.07 1.2624 0.9802 3063627 Maybridge4_001422 N#Cc1sc2nc3ccccc3n2c1/N=C/N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A15 compound treatment 0.328 0.0928 0.97 0.309 0.0747 0.89 1.3211 0.9991 3178647 Maybridge4_001423 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)Oc3ccccc3N4CCCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A16 compound treatment 0.329 0.0938 0.99 0.355 0.121 1.44 1.7177 0.9826 1004868 Maybridge4_001424 Sc1ncnc2n(ncc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A17 compound treatment 0.243 0.00781 0.08 0.264 0.0297 0.36 0.3092 0.8481 1225276 Maybridge4_001425 COc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccc(cc3)C(C)(C)C)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A18 compound treatment 0.249 0.0138 0.15 0.231 -0.00331 -0.04 0.0746 0.4958 1212340 Maybridge4_001426 COc1ccc(cc1)C(=O)Nc2ccc(nc2)N3CCN(CC3)C(=O)OC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A19 compound treatment 0.33 0.0948 1.0 0.327 0.0927 1.11 1.4883 0.9986 1490823 Maybridge4_001427 Fc1ccc(cc1)c2cn3cccc(OCc4ccc(Cl)c(Cl)c4)c3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A20 compound treatment 0.237 0.00181 0.02 0.214 -0.0203 -0.24 -0.1584 -0.6497 1164040 Maybridge4_001428 Oc1ccccc1C(=O)Nc2ccc(NC(=O)Nc3ccccc3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A21 compound treatment 0.118 -0.117 -1.23 0.138 -0.0963 -1.15 -1.6851 -0.9995 1589639 Maybridge4_001429 O=C(Nc1ccc(OCc2ccccc2)cc1)N3CCN(CC3)c4ccccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A22 compound treatment 0.208 -0.0272 -0.29 0.241 0.00669 0.08 -0.1453 -0.4901 1548910 Maybridge4_001430 CCOC(=O)Cc1csc(NS(=O)(=O)c2cn(C)cn2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A23 mock treatment 0.223 -0.0122 -0.13 0.242 0.00769 0.09 -0.0255 -0.1616 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 A24 mock treatment 0.264 0.0288 0.3 0.273 0.0387 0.46 0.5413 0.9788 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B01 compound treatment 0.599 0.364 3.82 0.597 0.363 4.34 5.7702 0.998 3178648 Maybridge4_001431 Clc1ccc2c(Oc3ccc(NS(=O)(=O)c4ccc(s4)c5ccccn5)cn3)ncnc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B02 compound treatment 0.643 0.408 4.28 0.542 0.308 3.68 5.6317 0.9972 3178649 Maybridge4_001432 O=C(c1sc(Nc2ccc3OCCOc3c2)nc1c4ccccc4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B03 compound treatment 0.172 -0.0632 -0.66 0.182 -0.0523 -0.63 -0.9118 -0.9996 1669153 Maybridge4_001433 CCc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B04 compound treatment 0.389 0.154 1.62 0.277 0.0427 0.51 1.5034 0.8874 3178650 Maybridge4_001434 O=C(NCc1ccsc1)c2ccc3OCCCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B05 compound treatment 0.8 0.565 5.93 0.65 0.416 4.97 7.7114 0.9962 3063628 Maybridge4_001435 CCc1c(nnc2cc(C)nn12)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B06 compound treatment 0.651 0.416 4.37 0.54 0.306 3.66 5.6742 0.9961 1347207 Maybridge4_001436 COc1ccc(Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B07 compound treatment 0.181 -0.0542 -0.57 0.165 -0.0693 -0.83 -0.9888 -0.9831 1134750 Maybridge4_001437 CC(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B08 compound treatment 0.344 0.109 1.14 0.259 0.0247 0.3 1.017 0.8616 1513237 Maybridge4_001438 CSc1c2CCCCc2c(C#N)c3nc4ccccc4n13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B09 compound treatment 0.255 0.0198 0.21 0.273 0.0387 0.46 0.4744 0.9349 3178651 Maybridge4_001439 Fc1ccc(cc1)S(=O)(=O)CCSc2nnc(OC(=O)c3cccs3)n2C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B10 compound treatment 0.179 -0.0562 -0.59 0.166 -0.0683 -0.82 -0.9952 -0.9872 3063629 Maybridge4_001440 N#Cc1c(/N=C/N2CCCCC2)nc3CCCCc3c1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B11 compound treatment 0.33 0.0948 1.0 0.295 0.0607 0.73 1.2176 0.988 3178652 Maybridge4_001441 COC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B12 compound treatment 0.164 -0.0712 -0.75 0.184 -0.0503 -0.6 -0.9543 -0.9942 3063630 Maybridge4_001442 O=C(CN1C(=O)c2ccccc2S1(=O)=O)c3ccc4OCCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B13 compound treatment 0.302 0.0668 0.7 0.269 0.0347 0.42 0.7896 0.9686 1504288 Maybridge4_001443 COc1ccc(cc1)C(=O)Nc2ccc3[nH]ccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B14 compound treatment 0.124 -0.111 -1.17 0.124 -0.11 -1.32 -1.759 -0.9981 1589222 Maybridge4_001444 OC(=O)CCC(=O)NCC1COc2ccccc2O1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B15 compound treatment 0.419 0.184 1.93 0.382 0.148 1.77 2.6145 0.999 1127725 Maybridge4_001445 CCOC(=O)c1nn(c2ccccc2)c3nc(Nc4ccc(C)cc4)cc(=O)n13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B16 compound treatment 0.076 -0.159 -1.67 0.077 -0.157 -1.88 -2.5131 -0.9983 1720808 Maybridge4_001446 O=C(CSc1ccccc1)N2c3ccccc3Sc4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B17 compound treatment 0.572 0.337 3.54 0.45 0.216 2.58 4.3261 0.988 1598554 Maybridge4_001447 COc1ccc(cc1)C(=O)c2c(NC(=O)C)sc3CN(CCc23)C(=O)OC(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B18 compound treatment 0.312 0.0768 0.81 0.351 0.117 1.4 1.5576 0.966 3063652 Maybridge4_001448 C/C(=N\O)/C(C)(C)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B19 compound treatment 0.243 0.00781 0.08 0.203 -0.0313 -0.37 -0.2069 -0.5395 3063653 Maybridge4_001449 Oc1nnc(SCC(=O)c2ccc(cc2)N3CCOCC3)n1C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B20 compound treatment 0.32 0.0848 0.89 0.243 0.00869 0.1 0.7034 0.7843 3063654 Maybridge4_001450 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)Nc3ccccc3)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B21 compound treatment 0.224 -0.0112 -0.12 0.197 -0.0373 -0.45 -0.3988 -0.8638 3063655 Maybridge4_001451 Cc1cc2c(NC(=O)COCC(=O)O)cccc2nn1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B22 compound treatment 0.201 -0.0342 -0.36 0.163 -0.0713 -0.85 -0.8572 -0.926 3178653 Maybridge4_001452 CCOC(=O)N1CCC(CC1)NC(=O)c2snnc2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B23 mock treatment 0.235 -1.88E-4 0.0 0.239 0.00469 0.06 0.0383 0.6819 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 B24 mock treatment 0.2 -0.0352 -0.37 0.249 0.0147 0.18 -0.1371 -0.3349 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C01 compound treatment 0.398 0.163 1.71 0.458 0.224 2.68 3.1016 0.9766 3178654 Maybridge4_001453 COc1ccc(cc1)n2ccc(nc2=S)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C02 compound treatment 0.118 -0.117 -1.23 0.102 -0.132 -1.58 -1.9897 -0.9923 1547772 Maybridge4_001454 Cc1c(cnn1c2ccc(F)cc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C03 compound treatment 0.106 -0.129 -1.36 0.102 -0.132 -1.58 -2.0788 -0.9971 1661624 Maybridge4_001455 Cc1ccc(cc1)C(=O)Nc2ccc3ccccc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C04 compound treatment 0.593 0.358 3.76 0.527 0.293 3.5 5.1335 0.9994 1628233 Maybridge4_001456 CCCCN1Cc2c(C1=O)n(CC(=O)c3ccc(OC)cc3)c4cc(nn4c2=O)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C05 compound treatment 0.382 0.147 1.54 0.38 0.146 1.74 2.3228 0.9981 1204335 Maybridge4_001457 O=C1N(CNc2ccccc2)C(=O)C3=C1CCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C06 compound treatment 0.344 0.109 1.14 0.264 0.0297 0.36 1.0593 0.8851 3178655 Maybridge4_001458 COc1ccccc1C2CCN(Cc3sc4ccccc4c3C)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C07 compound treatment 0.222 -0.0132 -0.14 0.188 -0.0463 -0.55 -0.4897 -0.8575 1326929 Maybridge4_001459 Cc1ccc(cc1C)C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C08 compound treatment 0.686 0.451 4.73 0.546 0.312 3.73 5.9849 0.993 1479015 Maybridge4_001460 O=C(Nc1ccccc1N2CCOCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C09 compound treatment 0.188 -0.0472 -0.5 0.182 -0.0523 -0.63 -0.793 -0.9933 1487787 Maybridge4_001461 CCCc1cnc(nc1)N2CCN(CC2)S(=O)(=O)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C10 compound treatment 0.234 -0.00119 -0.01 0.201 -0.0333 -0.4 -0.2906 -0.7289 3063656 Maybridge4_001462 Cn1cc(c(n1)C(F)(F)F)S(=O)(=O)Nc2ccccc2N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C11 compound treatment 1.439 1.2 12.64 1.455 1.22 14.6 19.2673 0.9974 3178656 Maybridge4_001463 COc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C12 compound treatment 1.158 0.923 9.69 1.003 0.769 9.2 13.3565 0.9997 3063657 Maybridge4_001464 C(/N=C/1\S/C(=N/c2ccccc2)/C/3=C1/CCCC3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C13 compound treatment 0.409 0.174 1.83 0.291 0.0567 0.68 1.7704 0.9091 1606533 Maybridge4_001465 OC(=O)CC(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C14 compound treatment 0.275 0.0398 0.42 0.226 -0.00831 -0.1 0.2253 0.5243 3178742 Maybridge4_001466 Clc1ccc(/C=N/n2cnc3n(ncc3c2=N)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C15 compound treatment 0.158 -0.0772 -0.81 0.164 -0.0703 -0.84 -1.1681 -0.9998 1551950 Maybridge4_001467 CCOC(=O)c1cn(nc1N)C(=O)CCSc2ccc(OC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C16 compound treatment 0.343 0.108 1.13 0.31 0.0757 0.91 1.441 0.9939 1274385 Maybridge4_001468 CCOC(=O)C1=C(N)Oc2c(C1c3ccccc3)c(=O)oc4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C17 compound treatment 0.499 0.264 2.77 0.38 0.146 1.74 3.1917 0.975 1585094 Maybridge4_001469 O=S(=O)(N(CCC#N)Cc1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C18 compound treatment 0.303 0.0678 0.71 0.272 0.0377 0.45 0.8225 0.9757 1144333 Maybridge4_001470 CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C19 compound treatment 0.144 -0.0912 -0.96 0.13 -0.104 -1.25 -1.5597 -0.9914 1395168 Maybridge4_001471 OC(=O)c1ccccc1C(=O)NC2CCCCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C20 compound treatment 0.192 -0.0432 -0.45 0.179 -0.0553 -0.66 -0.7887 -0.983 3178743 Maybridge4_001472 Oc1nnc(SCC(=O)c2ccc3OCCOc3c2)n1c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C21 compound treatment 0.209 -0.0262 -0.28 0.222 -0.0123 -0.15 -0.2986 -0.9572 1500505 Maybridge4_001473 CCOC(=O)c1cc(C)nc(N2CCC(CC2)C(=O)N)c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C22 compound treatment 0.293 0.0578 0.61 0.239 0.00469 0.06 0.469 0.7691 3178744 Maybridge4_001474 CCOC(=O)c1cnn(C(=O)c2snnc2C)c1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C23 mock treatment 0.211 -0.0242 -0.25 0.199 -0.0353 -0.42 -0.4784 -0.9704 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 C24 mock treatment 0.253 0.0178 0.19 0.215 -0.0193 -0.23 -0.0311 -0.1046 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D01 compound treatment 0.183 -0.0522 -0.55 0.209 -0.0253 -0.3 -0.6017 -0.9609 1160532 Maybridge4_001475 Clc1ccc2c(Oc3ccc(NC(=O)Nc4ccccc4)cn3)ncnc2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D02 compound treatment 0.171 -0.0642 -0.67 0.165 -0.0693 -0.83 -1.0631 -0.9947 3063658 Maybridge4_001476 Oc1ccc(cc1O)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D03 compound treatment 0.554 0.319 3.35 0.552 0.318 3.8 5.0553 0.998 1237081 Maybridge4_001477 CN(C1CCCCC1)S(=O)(=O)c2ccc3ccccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D04 compound treatment 0.177 -0.0582 -0.61 0.164 -0.0703 -0.84 -1.027 -0.9877 3063659 Maybridge4_001478 OC(CN1CCN(CC1)C2c3ccccc3-c4ccccc24)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D05 compound treatment 0.041 -0.194 -2.04 0.065 -0.169 -2.03 -2.8745 -1.0 1413068 Maybridge4_001479 COC(=O)c1nn(c2ccccc2)c(=O)c3c(N)sc(C)c13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D06 compound treatment 1.237 1.0 10.52 1.222 0.988 11.82 15.7959 0.9983 3178745 Maybridge4_001480 C(On1nnc2ccccc12)c3ccccc3COn4nnc5ccccc45 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D07 compound treatment 0.482 0.247 2.59 0.441 0.207 2.47 3.5816 0.9997 3063660 Maybridge4_001481 CCN(C(=O)c1ccc2OCCc2c1)c3cccc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D08 compound treatment 0.176 -0.0592 -0.62 0.167 -0.0673 -0.81 -1.009 -0.9918 1525376 Maybridge4_001482 CC(=O)N(C(=O)C)c1cc(C)c(C#N)c2nc3ccccc3n12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D09 compound treatment 0.382 0.147 1.54 0.307 0.0727 0.87 1.7053 0.9633 3063661 Maybridge4_001483 Cc1nnsc1c2nnc(SCC(=O)c3ccc(C)cc3)n2C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D10 compound treatment 0.42 0.185 1.94 0.366 0.132 1.58 2.4866 0.9946 1489082 Maybridge4_001484 Cn1c2ccccc2n3c(=O)cc(c(C#N)c13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D11 compound treatment 0.197 -0.0382 -0.4 0.15 -0.0843 -1.01 -0.9969 -0.9183 1735545 Maybridge4_001485 CN(CCc1ccccn1)C(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D12 compound treatment 0.111 -0.124 -1.3 0.15 -0.0843 -1.01 -1.6356 -0.9919 3178746 Maybridge4_001486 Oc1ccccc1C(=O)NC(=O)c2ccccc2Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D13 compound treatment 1.446 1.21 12.72 1.443 1.21 14.46 19.2178 0.9979 3178747 Maybridge4_001487 C1CCC(CC1)/N=C/2\S/C(=N\c3ccccc3)/C/4=C2/CCCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D14 compound treatment 0.199 -0.0362 -0.38 0.148 -0.0863 -1.03 -0.999 -0.9078 3063662 Maybridge4_001488 OC(=O)CCCC(=O)N1CCN(CC1)c2ncccn2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D15 compound treatment 0.63 0.395 4.15 0.456 0.222 2.65 4.8076 0.9767 1539797 Maybridge4_001489 CCOC(=O)C1=NN(c2ccccc2)C3(C1c4ccc(C)cc4)C(=O)c5ccccc5C3=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D16 compound treatment 0.355 0.12 1.26 0.29 0.0557 0.67 1.3609 0.9558 1582785 Maybridge4_001490 Cc1cc(C)c2c(n1)sc3c(=O)n(CC(=O)c4ccccc4)cnc32 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D17 compound treatment 0.179 -0.0562 -0.59 0.178 -0.0563 -0.67 -0.8937 -0.9978 3178748 Maybridge4_001491 OC(=O)c1ccc(cc1)c2cn3cccnc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D18 compound treatment 0.181 -0.0542 -0.57 0.167 -0.0673 -0.81 -0.9719 -0.9855 3063663 Maybridge4_001492 C/C(=N\O)/C(C)(C)Nc1ccc(Cl)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D19 compound treatment 1.371 1.14 11.93 1.285 1.05 12.57 17.3241 0.9997 1236138 Maybridge4_001493 Cc1nc(Nc2ccccc2)sc1C(=O)c3cc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D20 compound treatment 0.365 0.13 1.36 0.321 0.0867 1.04 1.6974 0.9909 3063664 Maybridge4_001494 FC(F)(F)c1ccccc1NS(=O)(=O)c2ccc3OCCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D21 compound treatment 0.18 -0.0552 -0.58 0.186 -0.0483 -0.58 -0.8186 -1.0 3178749 Maybridge4_001495 O=C(NCCN1CCNC1=O)c2ccc3nccnc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D22 compound treatment 0.424 0.189 1.98 0.348 0.114 1.36 2.364 0.9831 3178750 Maybridge4_001496 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D23 mock treatment 0.229 -0.00619 -0.06 0.247 0.0127 0.15 0.0614 0.3718 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 D24 mock treatment 0.211 -0.0242 -0.25 0.22 -0.0143 -0.17 -0.3007 -0.9816 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E01 compound treatment 0.613 0.378 3.97 0.566 0.332 3.97 5.6119 1.0 3063665 Maybridge4_001497 Cc1ccc(cc1)c2ccn(c3ccc(C)c(Cl)c3)c(=S)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E02 compound treatment 0.186 -0.0492 -0.52 0.175 -0.0593 -0.71 -0.8671 -0.9878 1172555 Maybridge4_001498 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E03 compound treatment 0.085 -0.15 -1.58 0.099 -0.135 -1.62 -2.2601 -0.9999 1326393 Maybridge4_001499 OC(=O)c1ccccc1C(=O)N2CCN(Cc3ccncc3)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E04 compound treatment 0.287 0.0518 0.54 0.257 0.0227 0.27 0.5767 0.9484 1616068 Maybridge4_001500 Clc1ccccc1N2CCN(CC2)C3=Cc4ccccc4CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E05 compound treatment 1.075 0.84 8.82 1.026 0.792 9.47 12.9347 0.9994 1429251 Maybridge4_001501 O=C(NC1CCCc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E06 compound treatment 0.101 -0.134 -1.41 0.114 -0.12 -1.44 -2.0144 -0.9999 1274546 Maybridge4_001502 Cc1c(CN2CCc3ccccc3C2)sc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E07 compound treatment 0.195 -0.0402 -0.42 0.193 -0.0413 -0.49 -0.648 -0.9969 1237910 Maybridge4_001503 O=C(Nc1ccc(CN2CCS(=O)(=O)CC2)cc1)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E08 compound treatment 0.248 0.0128 0.13 0.187 -0.0473 -0.57 -0.3051 -0.5244 1710600 Maybridge4_001504 Cn1cnc(c1)S(=O)(=O)Nc2ccccc2N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E09 compound treatment 0.244 0.00881 0.09 0.219 -0.0153 -0.18 -0.0641 -0.3123 1424693 Maybridge4_001505 Cc1ccc(NC(=O)N(CCC(=O)O)Cc2ccccc2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E10 compound treatment 0.16 -0.0752 -0.79 0.158 -0.0763 -0.91 -1.204 -0.9974 1251028 Maybridge4_001506 CC(C)(C)c1cn2cccc(OCc3ccc(Cl)c(Cl)c3)c2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E11 compound treatment 0.457 0.222 2.33 0.401 0.167 1.99 3.0575 0.997 1143941 Maybridge4_001507 O=S(=O)(NC1CCCc2ccccc12)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E12 compound treatment 0.437 0.202 2.12 0.452 0.218 2.6 3.3404 0.9948 3178751 Maybridge4_001508 Nc1c(cnn1c2ccccc2)c3n[nH]c(=S)n3c4ccc(Cl)cc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E13 compound treatment 0.171 -0.0642 -0.67 0.163 -0.0713 -0.85 -1.08 -0.9932 3063666 Maybridge4_001509 FC(F)(F)c1ccn(n1)c2ccc(NC(=O)Nc3ccccc3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E14 compound treatment 1.205 0.97 10.19 1.177 0.943 11.28 15.1776 0.9987 3178752 Maybridge4_001510 CCOC(=O)COc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E15 compound treatment 0.185 -0.0502 -0.53 0.224 -0.0103 -0.12 -0.46 -0.8497 1607723 Maybridge4_001511 CCOC(=O)c1cnn(C(=O)c2c(C)nc3ccccn23)c1N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E16 compound treatment 0.511 0.276 2.9 0.483 0.249 2.98 4.1523 0.9999 1572679 Maybridge4_001512 Cc1nn(c2ccccc2)c3[nH]c(=O)c(C#N)c(c4cccs4)c13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E17 compound treatment 0.166 -0.0692 -0.73 0.135 -0.0993 -1.19 -1.354 -0.9722 1609957 Maybridge4_001513 O=S(=O)(N(CCC#N)CCc1ccccn1)c2ccc3OCCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E18 compound treatment 0.496 0.261 2.74 0.43 0.196 2.34 3.5925 0.9969 1377637 Maybridge4_001514 S=C(Nc1ccc2OCCOc2c1)Nc3ccccc3N4CCOCC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E19 compound treatment 0.205 -0.0302 -0.32 0.15 -0.0843 -1.01 -0.9375 -0.8866 1175800 Maybridge4_001515 OC(=O)CCC(=O)NC1CCCCNC1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E20 compound treatment 0.298 0.0628 0.66 0.302 0.0677 0.81 1.0391 0.9948 1593716 Maybridge4_001516 CC(c1ccccc1)n2c(O)nnc2SCc3cc(=O)oc4cc(O)ccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E21 compound treatment 0.375 0.14 1.47 0.32 0.0857 1.03 1.7632 0.9846 1417192 Maybridge4_001517 CCOC(=O)C1CCN(CC1)C(=O)c2ccc(CC)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E22 compound treatment 0.246 0.0108 0.11 0.221 -0.0133 -0.16 -0.0323 -0.1653 3063667 Maybridge4_001518 Cc1nnsc1c2nnc(SCC(=O)N(C3CCCCC3)c4ccccc4)n2C5CC5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E23 mock treatment 0.211 -0.0242 -0.25 0.198 -0.0363 -0.43 -0.4868 -0.9673 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 E24 mock treatment 0.244 0.00881 0.09 0.237 0.00269 0.03 0.0882 0.9 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F01 compound treatment 0.307 0.0718 0.75 0.27 0.0357 0.43 0.8352 0.9637 1399434 Maybridge4_001519 Cc1ccc(cc1)C(O)COC2=NCNc3cc(Cl)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F02 compound treatment 0.517 0.282 2.96 0.476 0.242 2.89 4.1376 0.9999 3063693 Maybridge4_001520 Clc1ccc(c(Cl)c1)S(=O)(=O)CCN2C(=O)c3ccccc3S2(=O)=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F03 compound treatment 0.817 0.582 6.11 0.738 0.504 6.03 8.5821 1.0 1228123 Maybridge4_001521 COC(=O)c1cc(oc1C)S(=O)(=O)N(C)C2CCCCC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F04 compound treatment 0.207 -0.0282 -0.3 0.214 -0.0203 -0.24 -0.3812 -0.9952 3063694 Maybridge4_001522 Cc1nc(sc1c2nnc(o2)c3cccc4ccccc34)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F05 compound treatment 0.341 0.106 1.11 0.288 0.0537 0.64 1.24 0.9661 1500694 Maybridge4_001523 CC(=O)Nc1cc(nn(c2ccccc2)c1=O)C(=O)c3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F06 compound treatment 0.233 -0.00219 -0.02 0.231 -0.00331 -0.04 -0.0443 -0.9664 3063695 Maybridge4_001524 S=c1[nH]nc(c2ccncc2)n1/N=C/c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F07 compound treatment 0.182 -0.0532 -0.56 0.169 -0.0653 -0.78 -0.9476 -0.9865 1217417 Maybridge4_001525 CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C(=O)c4ccccc4C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F08 compound treatment 0.318 0.0828 0.87 0.278 0.0437 0.52 0.9846 0.9703 1688932 Maybridge4_001526 NNC(=O)Cn1nc(c2ccccc2)c(c(C#N)c1=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F09 compound treatment 0.29 0.0548 0.58 0.268 0.0337 0.4 0.6921 0.9848 3178837 Maybridge4_001527 CCc1cc(C(=O)c2ccc(OC)cc2)c(NC(=O)c3ccc(cc3)C(F)(F)F)s1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F10 compound treatment 0.799 0.564 5.92 0.696 0.462 5.52 8.0931 0.9994 1686628 Maybridge4_001528 NNC(=O)c1oc2nc(cc(c3ccccc3)c2c1N)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F11 compound treatment 0.214 -0.0212 -0.22 0.246 0.0117 0.14 -0.0585 -0.2225 1119276 Maybridge4_001529 CN(CCc1ccccn1)C(=O)NS(=O)(=O)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F12 compound treatment 0.087 -0.148 -1.56 0.099 -0.135 -1.62 -2.2453 -0.9998 3063696 Maybridge4_001530 Fc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3C2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F13 compound treatment 0.423 0.188 1.97 0.313 0.0787 0.94 2.0605 0.9427 1398696 Maybridge4_001531 Cn1c(SCc2n[nH]c(=S)n2CC=C)nnc1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F14 compound treatment 0.097 -0.138 -1.45 0.102 -0.132 -1.58 -2.1456 -0.9991 3063697 Maybridge4_001532 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ncccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F15 compound treatment 0.378 0.143 1.5 0.34 0.106 1.26 1.9547 0.9964 3178838 Maybridge4_001533 Fc1ccc(cc1)C(=O)COc2nnc(SCCS(=O)(=O)c3ccc(F)cc3)n2C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F16 compound treatment 0.128 -0.107 -1.13 0.139 -0.0953 -1.14 -1.6024 -1.0 3063698 Maybridge4_001534 O=C/1N(Cc2ccccc2)c3ccccc3\C1=N\c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F17 compound treatment 0.718 0.483 5.07 0.651 0.417 4.99 7.1108 1.0 3178839 Maybridge4_001535 CCOC(=O)C1=NN(C(=C2C(=O)c3ccccc3C2=O)C1c4cccs4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F18 compound treatment 0.418 0.183 1.92 0.349 0.115 1.37 2.3279 0.9864 3063699 Maybridge4_001536 COc1ccc(cc1OC)C(=O)NC(=O)c2ccccc2O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F19 compound treatment 0.255 0.0198 0.21 0.19 -0.0443 -0.53 -0.2278 -0.3999 1600649 Maybridge4_001537 O=C(N1CCOCC1)c2ccc3OCCCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F20 compound treatment 0.3 0.0648 0.68 0.273 0.0387 0.46 0.8086 0.9823 3063700 Maybridge4_001538 CCN(c1cccc2ccccc12)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F21 compound treatment 0.153 -0.0822 -0.86 0.172 -0.0623 -0.75 -1.1375 -0.9973 3178840 Maybridge4_001539 O=C(NCCc1ccccn1)c2ccc3nccnc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F22 compound treatment 0.265 0.0298 0.31 0.227 -0.00731 -0.09 0.1595 0.4907 3178841 Maybridge4_001540 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2cccnc2Oc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F23 mock treatment 0.217 -0.0182 -0.19 0.242 0.00769 0.09 -0.07 -0.3303 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 F24 mock treatment 0.199 -0.0362 -0.38 0.231 -0.00331 -0.04 -0.2968 -0.7766 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G01 compound treatment 0.696 0.461 4.84 0.579 0.345 4.12 6.3383 0.9968 3063701 Maybridge4_001541 COc1ccc(cc1n2ccc(nc2=S)c3ccc(C)cc3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G02 compound treatment 0.123 -0.112 -1.18 0.102 -0.132 -1.58 -1.9525 -0.9894 1377005 Maybridge4_001542 Cc1ccc(cc1C)C(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G03 compound treatment 1.109 0.874 9.18 1.001 0.767 9.17 12.9757 1.0 1733649 Maybridge4_001543 CC(C)c1ccc(NC(=O)CSCc2csc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G04 compound treatment 0.267 0.0318 0.33 0.224 -0.0103 -0.12 0.149 0.4184 1177034 Maybridge4_001544 Cc1ccc(cc1)n2nnnc2c3c[nH]c4cc(Cl)c(F)cc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G05 compound treatment 0.216 -0.0192 -0.2 0.245 0.0107 0.13 -0.0521 -0.2182 3178842 Maybridge4_001545 Clc1ccc2OCC(=Cc2c1)C(=O)NC3CCCc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G06 compound treatment 0.161 -0.0742 -0.78 0.159 -0.0753 -0.9 -1.1881 -0.9974 1406389 Maybridge4_001546 CCCCc1ccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G07 compound treatment 0.195 -0.0402 -0.42 0.177 -0.0573 -0.69 -0.7833 -0.9728 1501125 Maybridge4_001547 Cc1nnsc1C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G08 compound treatment 0.379 0.144 1.51 0.337 0.103 1.23 1.9368 0.9947 3063702 Maybridge4_001548 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cc(sc2C(F)(F)F)C(=O)OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G09 compound treatment 0.993 0.758 7.96 0.873 0.639 7.64 11.0313 0.9998 1046775 Maybridge4_001549 O=C1CCN(Cc2ccccc2)C(=O)N1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G10 compound treatment 0.263 0.0278 0.29 0.289 0.0547 0.65 0.6692 0.9339 1245508 Maybridge4_001550 Clc1ccc(Cl)c(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G11 compound treatment 0.529 0.294 3.09 0.49 0.256 3.06 4.3452 1.0 3063703 Maybridge4_001551 COc1ccc(OCC2CN=C(Nc3ccc(C)cc3)S2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G12 compound treatment 0.372 0.137 1.44 0.339 0.105 1.25 1.9017 0.9977 3178843 Maybridge4_001552 Clc1ccc(/C=N/n2cnc3n(ncc3c2=O)c4ccccc4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G13 compound treatment 0.243 0.00781 0.08 0.249 0.0147 0.18 0.1823 0.9399 3063704 Maybridge4_001553 CC(C)N(CCC#N)C(=O)Nc1ccccc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G14 compound treatment 0.845 0.61 6.4 0.699 0.465 5.56 8.4601 0.9975 1165894 Maybridge4_001554 Cn1c(SCC=C)nnc1c2oc3nc(cc(c4ccccc4)c3c2N)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G15 compound treatment 0.989 0.754 7.92 0.891 0.657 7.86 11.1539 1.0 3063705 Maybridge4_001555 Cc1ccc(cc1)C(O)CSc2nnc(c3ccc4ccccc4c3)n2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G16 compound treatment 1.48 1.24 13.07 1.505 1.27 15.2 19.9948 0.9972 3178844 Maybridge4_001556 CC1CCc2c(C1)sc3ncn(CC=C)c(=O)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G17 compound treatment 0.27 0.0348 0.37 0.244 0.00969 0.12 0.3405 0.8877 1415511 Maybridge4_001557 CC(C)c1ccc(NC(=O)COc2ncnc3cc(Cl)ccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G18 compound treatment 0.529 0.294 3.09 0.472 0.238 2.84 4.1929 0.9992 3063706 Maybridge4_001558 CN(C1CCCCC1)C(=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G19 compound treatment 0.412 0.177 1.86 0.333 0.0987 1.18 2.148 0.9761 1222950 Maybridge4_001559 COc1ccc(Cc2nnc(SCC3CC3)n2c4ccc(F)cc4)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G20 compound treatment 0.278 0.0428 0.45 0.236 0.00169 0.02 0.3322 0.7381 3063707 Maybridge4_001560 Oc1nnc(SCc2cc(=O)oc3cc(O)ccc23)n1Cc4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G21 compound treatment 0.334 0.0988 1.04 0.314 0.0797 0.95 1.408 0.9991 1138850 Maybridge4_001561 CCOC(=O)C1CCN(CC1)C(=O)C2Cc3ccccc3N2C(=O)OCc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G22 compound treatment 0.235 -1.88E-4 0.0 0.233 -0.00131 -0.02 -0.0125 -0.7896 3063708 Maybridge4_001562 O=S(=O)(Nc1ccccc1C#N)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G23 mock treatment 0.181 -0.0542 -0.57 0.191 -0.0433 -0.52 -0.7689 -0.9989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 G24 mock treatment 0.252 0.0168 0.18 0.236 0.00169 0.02 0.1391 0.7829 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H01 compound treatment 0.215 -0.0202 -0.21 0.232 -0.00231 -0.03 -0.1695 -0.7927 3178845 Maybridge4_001563 Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1Cc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H02 compound treatment 0.217 -0.0182 -0.19 0.229 -0.00531 -0.06 -0.18 -0.8942 3063709 Maybridge4_001564 Cc1noc(C)c1c2nc(CN3C(=O)c4ccccc4S3(=O)=O)no2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H03 compound treatment 0.301 0.0658 0.69 0.235 6.87E-4 0.01 0.4946 0.7155 3178846 Maybridge4_001565 OC(=O)COCC(=O)Nc1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H04 compound treatment 0.23 -0.00519 -0.05 0.226 -0.00831 -0.1 -0.1088 -0.9599 1968939 Maybridge4_001566 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H05 compound treatment 1.071 0.836 8.78 1.028 0.794 9.5 12.9219 0.9992 3178847 Maybridge4_001567 COC(=O)C1N(N=C(C=C1C(=O)OC)C(=O)c2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H06 compound treatment 0.338 0.103 1.08 0.331 0.0967 1.16 1.5815 0.9994 1661945 Maybridge4_001568 Clc1cccc(NC(=O)N2CCCn3c(SCC=C)nnc23)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H07 compound treatment 0.239 0.00381 0.04 0.253 0.0187 0.22 0.1864 0.8207 3178848 Maybridge4_001569 Oc1nnc(SCC(=O)Nc2ccccc2)n1Cc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H08 compound treatment 0.29 0.0548 0.58 0.239 0.00469 0.06 0.4467 0.7723 1169532 Maybridge4_001570 NNC(=O)CN1c2ccccc2Sc3ccccc13 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H09 compound treatment 0.74 0.505 5.3 0.645 0.411 4.91 7.2235 0.9993 3178849 Maybridge4_001571 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)NC3Cc4ccccc4C3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H10 compound treatment 0.375 0.14 1.47 0.37 0.136 1.62 2.1863 0.9987 3063710 Maybridge4_001572 N#Cc1sc2nc3ccccc3n2c1/N=C/c4cccs4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H11 compound treatment 0.567 0.332 3.48 0.476 0.242 2.89 4.5089 0.9957 1394169 Maybridge4_001573 O=C(Nc1ccc(OCc2ccccc2)cc1)N3CCN(CC3)C(=O)C4COc5ccccc5O4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H12 compound treatment 0.191 -0.0442 -0.46 0.176 -0.0583 -0.7 -0.8215 -0.9804 3063711 Maybridge4_001574 O=C1Nc2ccccc2C1Cc3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H13 compound treatment 0.343 0.108 1.13 0.32 0.0857 1.03 1.5256 0.9988 1163008 Maybridge4_001575 S=C(Nc1ccccc1)C(C#N)c2nc3ccccc3[nH]2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H14 compound treatment 0.183 -0.0522 -0.55 0.183 -0.0513 -0.61 -0.8217 -0.9984 3063712 Maybridge4_001576 NS(=O)(=O)c1ccc(cc1)N(S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H15 compound treatment 0.646 0.411 4.31 0.396 0.162 1.93 4.4188 0.9345 3178934 Maybridge4_001577 CC(C)(C)c1ccc(cc1)c2noc(CSc3nnc(O)n3c4cccnc4)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H16 compound treatment 0.478 0.243 2.55 0.516 0.282 3.37 4.1864 0.9905 1688554 Maybridge4_001578 CCNc1nc(SCC(=O)OCC)nc2sc3CC(C)CCc3c12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H17 compound treatment 0.195 -0.0402 -0.42 0.183 -0.0513 -0.61 -0.7326 -0.9833 1408340 Maybridge4_001579 O=C1c2ccccc2-c3c1cnc4c(cnn34)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H18 compound treatment 0.227 -0.00819 -0.09 0.23 -0.00431 -0.05 -0.0973 -0.9701 3063713 Maybridge4_001580 O=C(NCC1CC1)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H19 compound treatment 0.255 0.0198 0.21 0.266 0.0317 0.38 0.4152 0.9601 1279297 Maybridge4_001581 Cc1ccc(Oc2ncccc2NC(=O)Nc3ccccc3)c4CCCc41 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H20 compound treatment 0.318 0.0828 0.87 0.256 0.0217 0.26 0.7985 0.8797 3178935 Maybridge4_001582 Cn1cnc(c1)S(=O)(=O)N(Cc2ccccc2)Cc3ccccc3N4CCC(CC4)C(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H21 compound treatment 0.308 0.0728 0.76 0.259 0.0247 0.3 0.7496 0.9144 3063714 Maybridge4_001583 CC(c1ccccc1)n2c(O)nnc2SCC(=O)c3csc4ccccc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H22 compound treatment 0.883 0.648 6.8 0.714 0.48 5.74 8.8692 0.9964 3178936 Maybridge4_001584 C1C(=Nc2ccccc2N=C1c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H23 mock treatment 0.224 -0.0112 -0.12 0.239 0.00469 0.06 -0.0434 -0.3335 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 H24 mock treatment 0.225 -0.0102 -0.11 0.252 0.0177 0.21 0.074 0.312 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I01 compound treatment 0.657 0.422 4.43 0.6 0.366 4.38 6.2264 1.0 3063715 Maybridge4_001585 Fc1ccc(cc1)c2oncc2c3nnnn3c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I02 compound treatment 0.136 -0.0992 -1.04 0.144 -0.0903 -1.08 -1.5007 -0.9998 1145291 Maybridge4_001586 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccc5nonc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I03 compound treatment 0.215 -0.0202 -0.21 0.233 -0.00131 -0.02 -0.161 -0.7574 1583736 Maybridge4_001587 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2CCCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I04 compound treatment 0.352 0.117 1.23 0.265 0.0307 0.37 1.1271 0.8802 1281751 Maybridge4_001588 CN(CC(=O)O)c1ncc(c2nnnn2c3ccccc3)c(n1)c4ccccc4Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I05 compound treatment 0.164 -0.0712 -0.75 0.202 -0.0323 -0.39 -0.802 -0.9529 3178937 Maybridge4_001589 Cc1nc(ccc1C(=O)Oc2ccccc2N3CCCCC3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I06 compound treatment 0.14 -0.0952 -1.0 0.143 -0.0913 -1.09 -1.4794 -0.999 1529830 Maybridge4_001590 Clc1cccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I07 compound treatment 0.232 -0.00319 -0.03 0.217 -0.0173 -0.21 -0.1701 -0.8109 1741796 Maybridge4_001591 Cc1cc(no1)C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I08 compound treatment 0.111 -0.124 -1.3 0.123 -0.111 -1.33 -1.864 -0.9999 1155868 Maybridge4_001592 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc3ccccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I09 compound treatment 1.241 1.01 10.56 1.093 0.859 10.27 14.7343 0.9999 1382929 Maybridge4_001593 COc1ccc(cc1)C(=O)N2CCc3cc(OC)c(OC)cc3C2C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I10 compound treatment 1.267 1.03 10.84 1.273 1.04 12.43 16.4502 0.9977 3178938 Maybridge4_001594 CC(C)(C)c1cc(NC(=O)Nc2ccccc2)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I11 compound treatment 0.234 -0.00119 -0.01 0.2 -0.0343 -0.41 -0.2991 -0.7283 3063716 Maybridge4_001595 Cc1nc(ccc1C(=O)NCC(O)c2ccccc2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I12 compound treatment 0.418 0.183 1.92 0.401 0.167 1.99 2.7679 0.9998 3178939 Maybridge4_001596 Cn1c(CSc2nnc(c3ccccc3)n2CC=C)nnc1SCc4ccc(F)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I13 compound treatment 0.274 0.0388 0.41 0.261 0.0267 0.32 0.514 0.9927 3063717 Maybridge4_001597 CC(C)N1CCC(=O)N(C1=O)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I14 compound treatment 0.301 0.0658 0.69 0.26 0.0257 0.31 0.7061 0.9334 1303953 Maybridge4_001598 O=c1[nH]cnc2n(c3ccccc3)c(=S)sc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I15 compound treatment 0.279 0.0438 0.46 0.267 0.0327 0.39 0.6019 0.9967 1733519 Maybridge4_001599 Cc1nc2ccccn2c1c3ccnc(SCC(=O)N(C4CCCCC4)c5ccccc5)n3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I16 compound treatment 0.447 0.212 2.22 0.418 0.184 2.2 3.127 1.0 1465542 Maybridge4_001600 Cc1ccc(cc1)C(=O)CN(Cc2ccccc2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I17 compound treatment 0.253 0.0178 0.19 0.224 -0.0103 -0.12 0.045 0.201 3063736 Maybridge4_001601 OC(=O)CC(CC(=O)Oc1ccccc1N2CCOCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I18 compound treatment 0.285 0.0498 0.52 0.28 0.0457 0.55 0.7565 0.9998 3063737 Maybridge4_001602 CC(C)N(Cc1ccccc1)C(=O)Nc2ccc(cc2)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I19 compound treatment 0.231 -0.00419 -0.04 0.225 -0.00931 -0.11 -0.1099 -0.9173 1622159 Maybridge4_001603 COc1ccc(Cc2nnc(SCC(=O)NC(C)C)n2c3ccc(F)cc3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I20 compound treatment 0.38 0.145 1.52 0.374 0.14 1.67 2.2572 0.9989 3063738 Maybridge4_001604 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCCS(=O)(=O)c3ccc(F)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I21 compound treatment 0.295 0.0598 0.63 0.267 0.0327 0.39 0.7207 0.974 1522253 Maybridge4_001605 CCOC(=O)C1CCN(CC1)C(=O)c2sc(nc2C)c3ccc4OCCc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I22 compound treatment 0.128 -0.107 -1.13 0.137 -0.0973 -1.16 -1.6193 -0.9999 3063739 Maybridge4_001606 O=S(=O)(Nc1ccccc1N2CCCCC2)c3cccc4nonc34 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I23 mock treatment 0.208 -0.0272 -0.29 0.218 -0.0163 -0.2 -0.3399 -0.9828 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 I24 mock treatment 0.26 0.0248 0.26 0.252 0.0177 0.21 0.3339 0.9947 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J01 compound treatment 0.368 0.133 1.39 0.335 0.101 1.2 1.8382 0.9973 1381618 Maybridge4_001607 CC(C)c1ccc(NC(=O)CSc2nnc(O)n2C(C)c3ccccc3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J02 compound treatment 1.265 1.03 10.82 1.147 0.913 10.92 15.3694 1.0 3063740 Maybridge4_001608 Cc1onc(c1CN2C(=O)c3ccccc3S2(=O)=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J03 compound treatment 0.316 0.0808 0.85 0.289 0.0547 0.65 1.0628 0.9917 1310898 Maybridge4_001609 Clc1cccc(NC(=O)Nc2ccccc2N3CCCCC3)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J04 compound treatment 0.241 0.00581 0.06 0.235 6.87E-4 0.01 0.049 0.7952 1473794 Maybridge4_001610 Fc1cn(Cc2c(Cl)cccc2Cl)c(=O)[nH]c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J05 compound treatment 0.557 0.322 3.38 0.489 0.255 3.05 4.5446 0.9987 1148553 Maybridge4_001611 CCOC(=O)c1nn(c2ccccc2)c(=O)c3c(N)c(C#N)c(cc13)c4ccco4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J06 compound treatment 0.065 -0.17 -1.79 0.059 -0.175 -2.1 -2.7471 -0.9968 2101411 Maybridge4_001612 O=C(Oc1c(C#N)sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c12)c5cccs5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J07 compound treatment 0.672 0.437 4.59 0.565 0.331 3.96 6.0417 0.9973 1624521 Maybridge4_001613 CC(c1ccccc1)n2c(OC(=O)N(C)C)nnc2SCC(=O)c3ccc4OCCOc4c3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J08 compound treatment 0.729 0.494 5.19 0.517 0.283 3.38 6.0589 0.9785 3063741 Maybridge4_001614 CCOC(=O)c1cnn(c1NC(=O)Nc2cccc(Cl)c2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J09 compound treatment 0.349 0.114 1.2 0.296 0.0617 0.74 1.3671 0.9732 3063742 Maybridge4_001615 Cc1cc(C)cc(OC(=O)c2ccc(Oc3cc(Cl)cc(Cl)c3)o2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J10 compound treatment 0.13 -0.105 -1.1 0.131 -0.103 -1.24 -1.6552 -0.9984 1606613 Maybridge4_001616 COc1cc(OC)c2nc(C)c3CN(Cc3c2c1)C(=O)Nc4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J11 compound treatment 0.302 0.0668 0.7 0.258 0.0237 0.28 0.6966 0.9205 3178940 Maybridge4_001617 CN(C(=O)c1nn(nc1C)c2ccccc2)c3nnc(s3)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J12 compound treatment 0.324 0.0888 0.93 0.2 -0.0343 -0.41 0.3693 0.3624 3063743 Maybridge4_001618 Cc1sc(nc1c2ccccc2)c3ccc(cc3)c4csnn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J13 compound treatment 0.422 0.187 1.96 0.361 0.127 1.52 2.4592 0.9919 3178941 Maybridge4_001619 S=c1[nH]nc(CCCCc2n[nH]c(=S)[nH]2)[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J14 compound treatment 0.251 0.0158 0.17 0.263 0.0287 0.34 0.3601 0.9445 3063744 Maybridge4_001620 O=C(Nc1ccccc1N2CCOCC2)C3=NNC(=O)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J15 compound treatment 0.108 -0.127 -1.34 0.132 -0.102 -1.22 -1.8101 -0.999 3178942 Maybridge4_001621 Cc1c(sc2ccc(Cl)cc12)C(=O)CSc3nnc(O)n3C4CC4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J16 compound treatment 1.058 0.823 8.64 0.915 0.681 8.14 11.8693 0.9996 1671368 Maybridge4_001622 O=C(CSc1nnc(o1)c2ccncc2)N3c4ccccc4Sc5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J17 compound treatment 0.335 0.0998 1.05 0.291 0.0567 0.68 1.2208 0.9778 3178943 Maybridge4_001623 CC(C)(C)c1cc(N/C=C/C(=O)c2ccc(Cl)cc2)no1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J18 compound treatment 0.132 -0.103 -1.08 0.186 -0.0483 -0.58 -1.1751 -0.9567 3178944 Maybridge4_001624 O=C(C1=NOC2(C1c3ccccc3)C(=O)c4ccccc4C2=O)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J19 compound treatment 0.409 0.174 1.83 0.349 0.115 1.37 2.2611 0.9901 1576744 Maybridge4_001625 Cc1ccc(Oc2ncccc2NC(=O)CC(CC(=O)O)c3ccccc3)c4CCCc41 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J20 compound treatment 0.258 0.0228 0.24 0.239 0.00469 0.06 0.2091 0.8497 1506454 Maybridge4_001626 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2cccs2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J21 compound treatment 0.36 0.125 1.31 0.329 0.0947 1.13 1.728 0.9974 3178945 Maybridge4_001627 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCC(=O)c3ccc(C#N)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J22 compound treatment 0.186 -0.0492 -0.52 0.194 -0.0403 -0.48 -0.7063 -0.9994 3063745 Maybridge4_001628 OC(=O)CSCC(=O)Nc1n[nH]c(SCc2ccc(Cl)cc2)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J23 mock treatment 0.28 0.0448 0.47 0.265 0.0307 0.37 0.5924 0.9925 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 J24 mock treatment 0.247 0.0118 0.12 0.258 0.0237 0.28 0.2881 0.9313 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K01 compound treatment 0.438 0.203 2.13 0.456 0.222 2.65 3.3817 0.9941 3178946 Maybridge4_001629 Cc1ccccc1c2oncc2c3nnnn3c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K02 compound treatment 0.197 -0.0382 -0.4 0.206 -0.0283 -0.34 -0.5231 -0.9965 1125361 Maybridge4_001630 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K03 compound treatment 0.203 -0.0322 -0.34 0.14 -0.0943 -1.13 -1.0369 -0.8803 1429606 Maybridge4_001631 CC(C)(C)c1ccc(NC(=O)NC2CCCc3ccccc23)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K04 compound treatment 0.442 0.207 2.17 0.388 0.154 1.84 2.8361 0.9966 1237562 Maybridge4_001632 CCOC(=O)C1CCCN(C1)C(=O)S(=O)(=O)c2ccc(s2)c3ccccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K05 compound treatment 0.205 -0.0302 -0.32 0.189 -0.0453 -0.54 -0.6075 -0.9674 3063746 Maybridge4_001633 Cc1ccc(cc1)S(=O)(=O)NC(=O)Oc2ccccc2N3CCOCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K06 compound treatment 0.136 -0.0992 -1.04 0.132 -0.102 -1.22 -1.6022 -0.9968 1225155 Maybridge4_001634 O=S(=O)(Nc1ccc(cc1)N2CCCCC2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K07 compound treatment 0.188 -0.0472 -0.5 0.203 -0.0313 -0.37 -0.6153 -0.9905 1255708 Maybridge4_001635 Nc1ccccc1C(=O)NCCN2CCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K08 compound treatment 0.068 -0.167 -1.76 0.078 -0.156 -1.87 -2.564 -0.9995 1132174 Maybridge4_001636 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc3OCCc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K09 compound treatment 0.961 0.726 7.62 0.725 0.491 5.87 9.5415 0.9917 1685251 Maybridge4_001637 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3nn(nc3C)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K10 compound treatment 0.244 0.00881 0.09 0.217 -0.0173 -0.21 -0.081 -0.3571 1481631 Maybridge4_001638 COc1ccc(cc1)C(=O)Nc2ccc(Oc3ncnc4cc(Cl)ccc34)nc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K11 compound treatment 0.299 0.0638 0.67 0.235 6.87E-4 0.01 0.4797 0.7157 1418693 Maybridge4_001639 OC(CNS(=O)(=O)c1ccccc1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K12 compound treatment 0.54 0.305 3.2 0.494 0.26 3.11 4.4607 0.9999 3179042 Maybridge4_001640 Clc1ccc(cc1)C(=O)CSc2nnc(CSc3nnc(c4ccccc4)n3CC=C)o2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K13 compound treatment 0.159 -0.0762 -0.8 0.16 -0.0743 -0.89 -1.1945 -0.9986 1429598 Maybridge4_001641 C(N1CCN(CC1)c2ccccn2)c3c[nH]c(n3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K14 compound treatment 0.283 0.0478 0.5 0.292 0.0577 0.69 0.8431 0.9878 1175807 Maybridge4_001642 C1Cc2nc3ncnn3c(N4CCN(CC4)c5ccccc5)c2C1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K15 compound treatment 0.4 0.165 1.73 0.331 0.0967 1.16 2.042 0.9808 1227234 Maybridge4_001643 CCOC(=O)c1cc(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K16 compound treatment 0.258 0.0228 0.24 0.215 -0.0193 -0.23 0.006 0.0181 3179043 Maybridge4_001644 Cc1onc(NC(=O)CSCC(=O)O)c1Br 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K17 compound treatment 0.322 0.0868 0.91 0.32 0.0857 1.03 1.3696 0.9983 1228665 Maybridge4_001645 O=C(Oc1ccccc1N2CCOCC2)c3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K18 compound treatment 0.26 0.0248 0.26 0.253 0.0187 0.22 0.3424 0.9971 3179044 Maybridge4_001646 CN(C1CCCCC1)C(=O)Nc2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K19 compound treatment 0.391 0.156 1.64 0.342 0.108 1.29 2.0682 0.993 3179045 Maybridge4_001647 COc1ccc(Cc2nnc(SCC(=O)C(C)(C)C)n2c3ccc(F)cc3)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K20 compound treatment 0.224 -0.0112 -0.12 0.221 -0.0133 -0.16 -0.1957 -0.9888 3063747 Maybridge4_001648 COc1cccc(NC(=O)NCCN2CCN=C2C)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K21 compound treatment 0.151 -0.0842 -0.88 0.149 -0.0853 -1.02 -1.347 -0.9974 1463967 Maybridge4_001649 Cc1ccc(cc1)C(=O)NC2CCCCNC2=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K22 compound treatment 0.37 0.135 1.42 0.413 0.179 2.14 2.5129 0.98 1183986 Maybridge4_001650 O=C(Nc1cccs1)Nc2nnc(s2)C3CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K23 mock treatment 0.199 -0.0362 -0.38 0.198 -0.0363 -0.43 -0.576 -0.9978 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 K24 mock treatment 0.255 0.0198 0.21 0.257 0.0227 0.27 0.3391 0.9914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L01 compound treatment 0.257 0.0218 0.23 0.297 0.0627 0.75 0.6923 0.8828 3179046 Maybridge4_001651 CC(C)c1ccc(NC(=O)CSc2nnc(O)n2C3CC3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L02 compound treatment 0.395 0.16 1.68 0.399 0.165 1.97 2.5801 0.9968 3063748 Maybridge4_001652 CC(C)(CC(=O)Nc1ccc(F)cc1)Sc2ccc(Cl)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L03 compound treatment 0.225 -0.0102 -0.11 0.244 0.00969 0.12 0.0063 0.0399 1296513 Maybridge4_001653 Cc1ccccc1NC(=O)Nc2ccccc2N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L04 compound treatment 0.181 -0.0542 -0.57 0.175 -0.0593 -0.71 -0.9042 -0.994 3179047 Maybridge4_001654 O=c1[nH]cc(N2CCN(Cc3ccccc3)CC2)c(=O)[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L05 compound treatment 1.317 1.08 11.36 1.263 1.03 12.31 16.7369 0.9992 1703134 Maybridge4_001655 CC(C)(C)c1ccc(Oc2ccc(NC(=O)c3ccccc3)cn2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L06 compound treatment 0.347 0.112 1.17 0.346 0.112 1.34 1.7753 0.9979 3179048 Maybridge4_001656 Cc1nc2n(CC=C)c(=S)sc2c(=O)n1/N=C/c3ccc(Cl)cc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L07 compound treatment 0.688 0.453 4.76 0.634 0.4 4.78 6.7442 1.0 3063749 Maybridge4_001657 CN(C)C(=O)Oc1nnc(SCC(=O)c2ccc3OCCOc3c2)n1C4Cc5ccccc5C4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L08 compound treatment 0.217 -0.0182 -0.19 0.252 0.0177 0.21 0.0146 0.0511 1284108 Maybridge4_001658 C1CCc2c(C1)sc3ncnc(Oc4ccccc4)c23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L09 compound treatment 0.106 -0.129 -1.36 0.099 -0.135 -1.62 -2.1042 -0.9961 1451783 Maybridge4_001659 Cc1ccc2cc(OC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)o3)ccc2n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L10 compound treatment 0.09 -0.145 -1.52 0.09 -0.144 -1.73 -2.2991 -0.9981 3063750 Maybridge4_001660 C=CCNC(=S)Nc1sc2CCCCc2c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L11 compound treatment 0.242 0.00681 0.07 0.209 -0.0253 -0.3 -0.1636 -0.5256 1501773 Maybridge4_001661 CC(C)N(Cc1ccccc1)C(=O)Nc2c(C)onc2c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L12 compound treatment 0.297 0.0618 0.65 0.27 0.0357 0.43 0.761 0.9793 3063751 Maybridge4_001662 Clc1ccc(cc1)C2CCC(CC2)C(=O)NCc3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L13 compound treatment 0.267 0.0318 0.33 0.24 0.00569 0.07 0.2844 0.834 3179049 Maybridge4_001663 Cc1nc2n(CC=C)c(=S)sc2c(=O)[nH]1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L14 compound treatment 0.233 -0.00219 -0.02 0.254 0.0197 0.24 0.1503 0.6351 3063752 Maybridge4_001664 COC(=O)c1cccc(NC(=O)C2=NNC(=O)CC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L15 compound treatment 0.236 8.12E-4 0.01 0.216 -0.0183 -0.22 -0.1489 -0.6791 1342676 Maybridge4_001665 Cc1noc(C)c1c2nc(CSc3nnc(O)n3C4CC4)no2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L16 compound treatment 0.199 -0.0362 -0.38 0.405 0.171 2.04 1.1753 0.5658 3179050 Maybridge4_001666 FC(F)(F)c1ccnc(SCn2c(=S)sc3ccccc23)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L17 compound treatment 0.045 -0.19 -2.0 0.048 -0.186 -2.23 -2.9887 -0.9985 3063753 Maybridge4_001667 Cc1ccnc(SCn2c(=S)sc3ccccc23)n1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L18 compound treatment 0.235 -1.88E-4 0.0 0.256 0.0217 0.26 0.1821 0.7017 3179051 Maybridge4_001668 CCOC(=O)C1=NN(C(=C2C(=O)c3ccccc3C2=O)S1)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L19 compound treatment 0.744 0.509 5.34 0.603 0.369 4.41 6.8978 0.9955 3063754 Maybridge4_001669 Cc1ccc(Oc2ncccc2NC(=O)c3ccc4OCCCOc4c3)c5CCCc51 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L20 compound treatment 0.267 0.0318 0.33 0.258 0.0237 0.28 0.4367 0.9966 3179052 Maybridge4_001670 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccc(C)c(Cl)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L21 compound treatment 0.378 0.143 1.5 0.316 0.0817 0.98 1.7517 0.9785 3179053 Maybridge4_001671 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCC(=O)Nc3ccccc3Cl 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L22 compound treatment 0.443 0.208 2.18 0.344 0.11 1.31 2.4713 0.9704 3063755 Maybridge4_001672 Fc1ccc(cc1)S(=O)(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L23 mock treatment 0.262 0.0268 0.28 0.219 -0.0153 -0.18 0.0696 0.2071 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 L24 mock treatment 0.263 0.0278 0.29 0.214 -0.0203 -0.24 0.0347 0.0913 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M01 compound treatment 0.214 -0.0212 -0.22 0.22 -0.0143 -0.17 -0.2784 -0.9916 1161393 Maybridge4_001673 Cc1c(cnc2cc3OCOc3cc12)c4nnnn4c5ccc(F)cc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M02 compound treatment 0.485 0.25 2.62 0.487 0.253 3.02 3.993 0.9975 3063756 Maybridge4_001674 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCN(CC3)c4ncccc4C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M03 compound treatment 0.673 0.438 4.6 0.545 0.311 3.72 5.8799 0.9944 1702105 Maybridge4_001675 Fc1ccccc1NC(=O)NC2CCCc3ccccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M04 compound treatment 0.286 0.0508 0.53 0.3 0.0657 0.79 0.9331 0.9822 1481828 Maybridge4_001676 OC(=O)c1ccc2nc3ccsc3c(=O)n2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M05 compound treatment 0.169 -0.0662 -0.7 0.2 -0.0343 -0.41 -0.7818 -0.9684 3063779 Maybridge4_001677 FC(F)(F)c1ccc(nc1)N2CCN(Cc3c[nH]nc3c4ccccc4)CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M06 compound treatment 0.27 0.0348 0.37 0.257 0.0227 0.27 0.4505 0.9892 3063780 Maybridge4_001678 O=S(=O)(N1CCC2(CC1)OCCO2)c3ccc(s3)c4ccccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M07 compound treatment 0.735 0.5 5.25 0.662 0.428 5.12 7.3302 0.9999 3063781 Maybridge4_001679 Cc1c(cnn1c2ccc(F)cc2)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M08 compound treatment 1.081 0.846 8.88 0.93 0.696 8.32 12.167 0.9995 1213448 Maybridge4_001680 O=C(Nc1csc2ccccc12)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M09 compound treatment 1.079 0.844 8.86 0.816 0.582 6.96 11.1877 0.9928 1543617 Maybridge4_001681 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)c3ccc(s3)c4ccccn4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M10 compound treatment 0.718 0.483 5.07 0.547 0.313 3.74 6.231 0.9888 1698439 Maybridge4_001682 Fc1ccc(cc1)C(=O)COc2ncnc3cc(Cl)ccc23 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M11 compound treatment 0.131 -0.104 -1.09 0.207 -0.0273 -0.33 -1.0048 -0.8799 1129209 Maybridge4_001683 CC(C)(C)c1ccc(NC(=O)Nc2ccc3OCCOc3c2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M12 compound treatment 0.221 -0.0142 -0.15 0.246 0.0117 0.14 -0.0065 -0.0317 1441238 Maybridge4_001684 CC(=O)N(C(=O)C)n1c(C)nc2c(sc3nnc(c4ccccc4)c(c5ccccc5)c32)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M13 compound treatment 0.105 -0.13 -1.37 0.084 -0.15 -1.8 -2.2385 -0.9909 1158309 Maybridge4_001685 O=C(Nc1ccccc1)Oc2ccccc2N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M14 compound treatment 0.767 0.532 5.59 0.614 0.38 4.54 7.1617 0.9947 1618806 Maybridge4_001686 C(N(Cc1ccccc1)c2c3CCCc3nc4ncnn24)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M15 compound treatment 0.757 0.522 5.48 0.58 0.346 4.14 6.7998 0.9904 1328356 Maybridge4_001687 Clc1ccc(cc1)C(=O)Nc2ccc3ccccc3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M16 compound treatment 0.456 0.221 2.32 0.34 0.106 1.26 2.534 0.9593 1356245 Maybridge4_001688 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCC(Cc4ccccc4)CC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M17 compound treatment 0.912 0.677 7.11 0.648 0.414 4.95 8.5262 0.9843 3063782 Maybridge4_001689 Clc1ccc(Sc2ncccc2C(=O)Oc3ccccc3N4CCOCC4)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M18 compound treatment 0.689 0.454 4.77 0.489 0.255 3.05 5.5249 0.9766 1407054 Maybridge4_001690 CN(C1CCCCC1)S(=O)(=O)c2ccc(s2)S(=O)(=O)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M19 compound treatment 0.403 0.168 1.76 0.307 0.0727 0.87 1.8612 0.947 1657796 Maybridge4_001691 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M20 compound treatment 0.224 -0.0112 -0.12 0.23 -0.00431 -0.05 -0.1196 -0.9317 3179139 Maybridge4_001692 CC1=NCCN1CCNC(=O)Nc2ccc(cc2)C(C)(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M21 compound treatment 0.214 -0.0212 -0.22 0.209 -0.0253 -0.3 -0.3715 -0.9885 1606643 Maybridge4_001693 O=C1N(CCCN2CCOCC2)C(Nc3ccccc13)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M22 compound treatment 0.281 0.0458 0.48 0.257 0.0227 0.27 0.5322 0.9633 1220768 Maybridge4_001694 OC(=O)COCC(=O)Nc1nnc(s1)C2CC2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M23 mock treatment 0.24 0.00481 0.05 0.187 -0.0473 -0.57 -0.3645 -0.6414 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 M24 mock treatment 0.229 -0.00619 -0.06 0.235 6.87E-4 0.01 -0.0401 -0.6127 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N01 compound treatment 0.223 -0.0122 -0.13 0.257 0.0227 0.27 0.1014 0.338 1585891 Maybridge4_001695 CCc1cccc(C)c1NC(=O)N(Cc2ccccc2)C(C)C 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N02 compound treatment 0.265 0.0298 0.31 0.251 0.0167 0.2 0.3626 0.9764 3063783 Maybridge4_001696 CC1CC(=O)Nc2ccccc2N1S(=O)(=O)c3ccc(s3)c4cc(on4)C(F)(F)F 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N03 compound treatment 0.198 -0.0372 -0.39 0.245 0.0107 0.13 -0.1858 -0.452 1262463 Maybridge4_001697 O=C(Nc1cccs1)Nc2ccccc2N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N04 compound treatment 0.396 0.161 1.69 0.385 0.151 1.8 2.4691 0.9995 3179140 Maybridge4_001698 Fc1cn(CC2CC(=NO2)c3ccccc3)c(=O)n(CC4CC(=NO4)c5ccccc5)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N05 compound treatment 0.181 -0.0542 -0.57 0.19 -0.0443 -0.53 -0.7773 -0.9994 1190724 Maybridge4_001699 CC(C)(C)c1ccc(Oc2ccc(NC(=O)Nc3cccs3)cn2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N06 compound treatment 0.278 0.0428 0.45 0.23 -0.00431 -0.05 0.2815 0.6219 3179141 Maybridge4_001700 COc1cc(/C=N/n2cnc3n(C)c(=S)sc3c2=O)ccc1O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N07 compound treatment 0.263 0.0278 0.29 0.255 0.0207 0.25 0.3816 0.9966 3063784 Maybridge4_001701 CN(C)C(=O)Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N08 compound treatment 0.264 0.0288 0.3 0.252 0.0177 0.21 0.3636 0.9847 3179142 Maybridge4_001702 CCOC(=O)c1c(SC)n(c2ccccc2)c(=S)n(c3ccccc3)c1=O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N09 compound treatment 0.32 0.0848 0.89 0.341 0.107 1.28 1.5325 0.9845 1226040 Maybridge4_001703 CC(=O)N1CCN(CC1)c2ccc(OC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)o3)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N10 compound treatment 0.235 -1.88E-4 0.0 0.254 0.0197 0.24 0.1652 0.7012 3063785 Maybridge4_001704 CN(C)/C=N\c1cc(C)c(C#N)c2nc3ccccc3n12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N11 compound treatment 0.186 -0.0492 -0.52 0.216 -0.0183 -0.22 -0.5202 -0.9271 1109792 Maybridge4_001705 OC(CN1CCOCC1)c2ccccc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N12 compound treatment 0.215 -0.0202 -0.21 0.222 -0.0123 -0.15 -0.2541 -0.9842 3179143 Maybridge4_001706 O=C(Cn1cc(nc1SCc2ccccc2)c3ccccc3)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N13 compound treatment 0.089 -0.146 -1.54 0.097 -0.137 -1.64 -2.2473 -0.9994 1537386 Maybridge4_001707 C=CCn1c(Sc2ncnc3n(ncc23)c4ccccc4)nnc1c5ccncc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N14 compound treatment 0.26 0.0248 0.26 0.229 -0.00531 -0.06 0.1393 0.5194 3063786 Maybridge4_001708 Fc1cc(F)cc(NC(=O)C2=NNC(=O)CC2)c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N15 compound treatment 0.246 0.0108 0.11 0.294 0.0597 0.71 0.5853 0.8094 1514475 Maybridge4_001709 CN(CCc1ccccn1)C(=O)c2c(C)onc2c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N16 compound treatment 0.297 0.0618 0.65 0.27 0.0357 0.43 0.761 0.9793 1207655 Maybridge4_001710 CCOc1ncc(c2nnnn2c3ccc(C)cc3)c(n1)c4cccc(Cl)c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N17 compound treatment 0.29 0.0548 0.58 0.251 0.0167 0.2 0.5482 0.8998 3179144 Maybridge4_001711 COc1ccc(cc1)C(=O)CSc2nnc(O)n2Cc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N18 compound treatment 0.502 0.267 2.8 0.366 0.132 1.58 3.0956 0.9629 3063787 Maybridge4_001712 CC1CN(CC(C)O1)c2ccc3nnc(c4ccc(cc4)C(F)(F)F)n3n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N19 compound treatment 0.286 0.0508 0.53 0.26 0.0257 0.31 0.5947 0.9656 3179145 Maybridge4_001713 FC(F)(F)c1ccc(cc1)C(=O)n2ccc(n2)c3cccs3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N20 compound treatment 0.396 0.161 1.69 0.302 0.0677 0.81 1.7669 0.9433 3179146 Maybridge4_001714 CCCc1c(cnn1c2ccccc2)C(=O)NC3CCN(CC3)C(=O)OCC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N21 compound treatment 0.323 0.0878 0.92 0.271 0.0367 0.44 0.9625 0.9424 3063788 Maybridge4_001715 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCc3nc4ccccc4s3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N22 compound treatment 0.319 0.0838 0.88 0.254 0.0197 0.24 0.789 0.8659 3179147 Maybridge4_001716 O=C(Nc1ccccc1)N2CCN(CC2)c3ncccn3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N23 mock treatment 0.24 0.00481 0.05 0.262 0.0277 0.33 0.27 0.8057 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 N24 mock treatment 0.236 8.12E-4 0.01 0.218 -0.0163 -0.2 -0.132 -0.6755 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O01 compound treatment 0.22 -0.0152 -0.16 0.243 0.00869 0.1 -0.0393 -0.2064 3063789 Maybridge4_001717 NC(=O)C1CCN(CC(O)(c2ccccc2)c3ccccc3)CC1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O02 compound treatment 0.34 0.105 1.1 0.324 0.0897 1.07 1.5372 0.9999 1354647 Maybridge4_001718 O=C1N(Cc2ccccc2)Cc3c1[nH]c4cc(nn4c3=O)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O03 compound treatment 0.261 0.0258 0.27 0.281 0.0467 0.56 0.5867 0.9449 1618786 Maybridge4_001719 O=C(NC1CCCc2ccccc12)Nc3ccc(OCc4ccccc4)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O04 compound treatment 0.31 0.0748 0.79 0.307 0.0727 0.87 1.1705 0.9987 1669773 Maybridge4_001720 NC(=O)c1ccc2nc3ccsc3c(=O)n2c1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O05 compound treatment 0.224 -0.0112 -0.12 0.236 0.00169 0.02 -0.0688 -0.5771 1411321 Maybridge4_001721 COc1ccc(cc1)c2n[nH]cc2CN3CCC(CC3)c4ccccc4OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O06 compound treatment 0.279 0.0438 0.46 0.288 0.0537 0.64 0.7796 0.9866 1472712 Maybridge4_001722 Cc1cc(=O)oc2cc(NC(=O)CC(CC(=O)O)c3ccccc3)ccc12 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O07 compound treatment 0.525 0.29 3.04 0.432 0.198 2.37 3.8248 0.9922 1310764 Maybridge4_001723 Fc1ccc(cc1)N2CCN(CC2)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O08 compound treatment 0.188 -0.0472 -0.5 0.197 -0.0373 -0.45 -0.6661 -0.9986 1239250 Maybridge4_001724 O=C(Nc1csc2ccccc12)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O09 compound treatment 0.417 0.182 1.91 0.382 0.148 1.77 2.5997 0.9992 1699746 Maybridge4_001725 COc1cc2CCN(C(C)c2cc1OC)C(=O)Nc3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O10 compound treatment 0.778 0.543 5.7 0.677 0.443 5.3 7.7764 0.9993 1354931 Maybridge4_001726 Cc1cc(no1)c2nc(CCn3c(=O)oc4ccc(C)cc34)no2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O11 compound treatment 0.279 0.0438 0.46 0.284 0.0497 0.59 0.7457 0.992 1136980 Maybridge4_001727 O=C(Nc1cccs1)Nc2ccc3OCCOc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O12 compound treatment 0.402 0.167 1.75 0.423 0.189 2.26 2.8352 0.9921 3179148 Maybridge4_001728 Clc1ccc(CS/C(=N\c2ccccc2)/C(C#N)c3nc4ccccc4[nH]3)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O13 compound treatment 0.562 0.327 3.43 0.437 0.203 2.43 4.1418 0.9855 1462458 Maybridge4_001729 Clc1ccsc1C(=O)Oc2ccccc2N3CCCCC3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O14 compound treatment 0.157 -0.0782 -0.82 0.173 -0.0613 -0.73 -1.0994 -0.9984 3179149 Maybridge4_001730 Cn1c(Sc2c3CCCc3nc4ncnn24)nnc1c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O15 compound treatment 0.221 -0.0142 -0.15 0.194 -0.0403 -0.48 -0.4464 -0.8843 1250957 Maybridge4_001731 Cn1nccc1NC(=O)COCC(=O)O 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O16 compound treatment 1.107 0.872 9.16 0.937 0.703 8.41 12.4194 0.9991 1424513 Maybridge4_001732 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3cc4c(C)cc(C)cc4[nH]3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O17 compound treatment 0.251 0.0158 0.17 0.23 -0.00431 -0.05 0.0809 0.4655 3063791 Maybridge4_001733 Cc1c(CN2CCN(CC2)c3ccccn3)sc4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O18 compound treatment 0.193 -0.0422 -0.44 0.236 0.00169 0.02 -0.299 -0.6742 1224470 Maybridge4_001734 CN(CCc1ccccn1)C(=O)c2cccnc2Oc3ccc(Cl)cc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O19 compound treatment 0.163 -0.0722 -0.76 0.133 -0.101 -1.21 -1.3932 -0.9745 1228387 Maybridge4_001735 O=S(=O)(Nc1ccccc1Oc2ccccc2)c3ccc(s3)c4ccon4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O20 compound treatment 0.202 -0.0332 -0.35 0.232 -0.00231 -0.03 -0.266 -0.7608 3179150 Maybridge4_001736 CC1=NCCN1CCNC(=O)Nc2cc(C)cc(C)c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O21 compound treatment 0.301 0.0658 0.69 0.278 0.0437 0.52 0.8584 0.9905 1638495 Maybridge4_001737 O=C1NCCN1CCN2C(Nc3ccccc3C2=O)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O22 compound treatment 0.27 0.0348 0.37 0.269 0.0347 0.42 0.552 0.998 3063793 Maybridge4_001738 Cc1nn(nc1c2nnc(o2)c3cccc4ccccc34)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O23 mock treatment 0.265 0.0298 0.31 0.226 -0.00831 -0.1 0.1511 0.4599 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 O24 mock treatment 0.268 0.0328 0.34 0.264 0.0297 0.36 0.4948 0.9999 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P01 compound treatment 0.239 0.00381 0.04 0.263 0.0287 0.34 0.271 0.7843 1685839 Maybridge4_001739 CN(C1CCCCC1)C(=O)NS(=O)(=O)c2ccc(C)cc2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P02 compound treatment 0.203 -0.0322 -0.34 0.204 -0.0303 -0.36 -0.4955 -0.9994 3063794 Maybridge4_001740 CC(C)c1ccc(NC(=O)C2=NNC(=O)CC2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P03 compound treatment 0.161 -0.0742 -0.78 0.232 -0.00231 -0.03 -0.5705 -0.7318 1248453 Maybridge4_001741 Oc1cc2c(coc2c3ccccc13)C(=O)c4ccc(Cl)cc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P04 compound treatment 0.168 -0.0672 -0.71 0.166 -0.0683 -0.82 -1.0769 -0.9973 1427084 Maybridge4_001742 S=C(Nc1ccccc1)N2CCCCC2c3cccnc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P05 compound treatment 0.425 0.19 1.99 0.429 0.195 2.33 3.0567 0.997 1556607 Maybridge4_001743 CC(C)(C)c1ccc(Oc2ccc(NC(=O)CC(C)(C)CC(=O)O)cn2)cc1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P06 compound treatment 0.339 0.104 1.09 0.309 0.0747 0.89 1.4028 0.9951 1313218 Maybridge4_001744 N#Cc1c2CCCc2c(N3CCCCC3)n4c5ccccc5nc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P07 compound treatment 0.281 0.0458 0.48 0.28 0.0457 0.55 0.7267 0.998 3063820 Maybridge4_001745 O=C(CSc1nnc(OC(=O)c2cccs2)n1C3CC3)c4ccc5OCCOc5c4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P08 compound treatment 0.41 0.175 1.84 0.334 0.0997 1.19 2.1416 0.9782 3063821 Maybridge4_001746 Cc1nn(cc1C2C=C(N=C3SCC(=O)N23)c4ccc(Cl)cc4)c5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P09 compound treatment 0.269 0.0338 0.36 0.285 0.0507 0.61 0.6799 0.9675 3063822 Maybridge4_001747 Cc1nc(cn1C)S(=O)(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P10 compound treatment 0.323 0.0878 0.92 0.31 0.0757 0.91 1.2925 1.0 3063823 Maybridge4_001748 O=C1N(Cc2ccc3nonc3c2)S(=O)(=O)c4ccccc14 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P11 compound treatment 0.223 -0.0122 -0.13 0.241 0.00669 0.08 -0.0339 -0.2248 1323976 Maybridge4_001749 Fc1ccc(cc1)C(=O)Nc2ccc3[nH]ccc3c2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P12 compound treatment 0.355 0.12 1.26 0.306 0.0717 0.86 1.4963 0.9825 3179235 Maybridge4_001750 Cc1ccccc1C(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P13 compound treatment 0.24 0.00481 0.05 0.282 0.0477 0.57 0.4392 0.7667 1141633 Maybridge4_001751 Cc1cc(NC(=O)Nc2ccccc2)n(n1)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P14 compound treatment 0.5 0.265 2.78 0.497 0.263 3.14 4.189 0.9981 3179236 Maybridge4_001752 Cc1c(/C=N/N2C(=O)CNC2=S)c(=O)n3c4ccccc4[nH]c3c1C#N 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P15 compound treatment 0.255 0.0198 0.21 0.256 0.0217 0.26 0.3306 0.994 3063825 Maybridge4_001753 O=C(NCCc1cccs1)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P16 compound treatment 0.219 -0.0162 -0.17 0.241 0.00669 0.08 -0.0636 -0.3387 3179237 Maybridge4_001754 O=C(Nc1ccc2OCCOc2c1)C3Cc4ccccc4N3C(=O)OCc5ccccc5 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P17 compound treatment 0.243 0.00781 0.08 0.231 -0.00331 -0.04 0.03 0.3292 3179238 Maybridge4_001755 Cc1noc(C)c1CSc2nnc(O)n2Cc3ccco3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P18 compound treatment 0.392 0.157 1.65 0.396 0.162 1.93 2.5325 0.9968 3063826 Maybridge4_001756 NNC(=O)C1N(N=C(C=C1C(=O)NN)C(=O)c2cccs2)c3ccccc3 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P19 compound treatment 1.337 1.1 11.57 1.248 1.01 12.13 16.7586 0.9997 3179239 Maybridge4_001757 Cc1cc(C(=O)n2ccc(n2)c3cccs3)c(C)o1 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P20 compound treatment 0.254 0.0188 0.2 0.235 6.87E-4 0.01 0.1455 0.7359 1543173 Maybridge4_001758 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(C)on2 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P21 compound treatment 0.283 0.0478 0.5 0.288 0.0537 0.64 0.8093 0.9926 3179240 Maybridge4_001759 COc1ccc(NC(=O)COCC(=O)O)cc1OC 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P22 compound treatment 0.637 0.402 4.22 0.992 0.758 9.07 9.3942 0.9395 3179241 Maybridge4_001760 Cc1onc(c1C(=O)NCC2COc3ccccc3O2)c4ccccc4 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P23 mock treatment 0.246 0.0108 0.11 0.274 0.0397 0.47 0.4161 0.8522 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.2053 P24 mock treatment 0.249 0.0138 0.15 0.241 0.00669 0.08 0.1592 0.9607 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A01 mock treatment 0.076 -0.0684 -0.72 0.234 0.0843 1.01 0.2047 0.1653 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A02 mock treatment 0.079 -0.0654 -0.69 0.079 -0.0707 -0.85 -1.0844 -0.9947 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A03 mock treatment 0.192 0.0476 0.5 0.202 0.0523 0.63 0.7954 0.9938 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A04 mock treatment 0.22 0.0756 0.79 0.235 0.0853 1.02 1.2826 0.9923 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A05 mock treatment 0.193 0.0486 0.51 0.189 0.0393 0.47 0.6929 0.9992 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A06 mock treatment 0.086 -0.0584 -0.61 0.102 -0.0477 -0.57 -0.8378 -0.9994 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A07 mock treatment 0.088 -0.0564 -0.59 0.182 0.0323 0.39 -0.1461 -0.2066 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A08 mock treatment 0.256 0.112 1.17 0.079 -0.0707 -0.85 0.2301 0.1592 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A09 mock treatment 0.085 -0.0594 -0.62 0.176 0.0263 0.31 -0.2192 -0.3136 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A10 mock treatment 0.207 0.0626 0.66 0.187 0.0373 0.45 0.7799 0.9821 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A11 mock treatment 0.183 0.0386 0.41 0.18 0.0303 0.36 0.5425 0.9984 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A12 mock treatment 0.098 -0.0464 -0.49 0.209 0.0593 0.71 0.1566 0.1819 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A13 mock treatment 0.079 -0.0654 -0.69 0.183 0.0333 0.4 -0.2045 -0.2575 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A14 mock treatment 0.089 -0.0554 -0.58 0.086 -0.0637 -0.76 -0.9509 -0.9911 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A15 mock treatment 0.087 -0.0574 -0.6 0.09 -0.0597 -0.71 -0.9319 -0.9964 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A16 mock treatment 0.185 0.0406 0.43 0.101 -0.0487 -0.58 -0.111 -0.1537 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A17 mock treatment 0.085 -0.0594 -0.62 0.083 -0.0667 -0.8 -1.006 -0.9926 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A18 mock treatment 0.095 -0.0494 -0.52 0.122 -0.0277 -0.33 -0.6018 -0.9766 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A19 mock treatment 0.179 0.0346 0.36 0.095 -0.0547 -0.65 -0.2064 -0.2756 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A20 mock treatment 0.206 0.0616 0.65 0.253 0.103 1.24 1.3309 0.9544 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A21 mock treatment 0.081 -0.0634 -0.67 0.197 0.0473 0.57 -0.0712 -0.0815 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A22 mock treatment 0.092 -0.0524 -0.55 0.193 0.0433 0.52 -0.0234 -0.0309 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A23 mock treatment 0.187 0.0426 0.45 0.101 -0.0487 -0.58 -0.0962 -0.1309 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base A24 mock treatment 0.186 0.0416 0.44 0.1 -0.0497 -0.6 -0.1121 -0.1518 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B01 mock treatment 0.261 0.117 1.22 0.227 0.0773 0.92 1.5194 0.9904 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B02 mock treatment 0.237 0.0926 0.97 0.235 0.0853 1.02 1.4088 0.9997 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B03 mock treatment 0.242 0.0976 1.02 0.194 0.0443 0.53 1.0991 0.9528 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B04 mock treatment 0.085 -0.0594 -0.62 0.208 0.0583 0.7 0.0516 0.0551 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B05 mock treatment 0.203 0.0586 0.62 0.204 0.0543 0.65 0.894 0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B06 mock treatment 0.182 0.0376 0.39 0.183 0.0333 0.4 0.5604 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B07 mock treatment 0.18 0.0356 0.37 0.102 -0.0477 -0.57 -0.1397 -0.2047 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B08 mock treatment 0.164 0.0196 0.21 0.171 0.0213 0.25 0.3252 0.9944 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B09 mock treatment 0.199 0.0546 0.57 0.101 -0.0487 -0.58 -0.0071 -0.0086 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B10 mock treatment 0.077 -0.0674 -0.71 0.096 -0.0537 -0.64 -0.9554 -0.9988 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B11 mock treatment 0.196 0.0516 0.54 0.118 -0.0317 -0.38 0.1145 0.1731 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B12 mock treatment 0.08 -0.0644 -0.68 0.257 0.107 1.28 0.429 0.2957 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B13 mock treatment 0.181 0.0366 0.38 0.085 -0.0647 -0.77 -0.2761 -0.3194 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B14 mock treatment 0.079 -0.0654 -0.69 0.159 0.00926 0.11 -0.4076 -0.5855 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B15 mock treatment 0.169 0.0246 0.26 0.174 0.0243 0.29 0.3877 0.9983 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B16 mock treatment 0.154 0.00957 0.1 0.164 0.0143 0.17 0.1917 0.9681 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B17 mock treatment 0.091 -0.0534 -0.56 0.091 -0.0587 -0.7 -0.8937 -0.9938 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B18 mock treatment 0.169 0.0246 0.26 0.16 0.0103 0.12 0.2693 0.9424 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B19 mock treatment 0.098 -0.0464 -0.49 0.22 0.0703 0.84 0.2496 0.2568 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B20 mock treatment 0.077 -0.0674 -0.71 0.203 0.0533 0.64 -0.0502 -0.0526 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B21 mock treatment 0.085 -0.0594 -0.62 0.185 0.0353 0.42 -0.143 -0.1898 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B22 mock treatment 0.149 0.00457 0.05 0.179 0.0293 0.35 0.2815 0.7966 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B23 mock treatment 0.089 -0.0554 -0.58 0.205 0.0553 0.66 0.0559 0.0634 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base B24 mock treatment 0.148 0.00357 0.04 0.1 -0.0497 -0.6 -0.3943 -0.6613 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C01 mock treatment 0.09 -0.0544 -0.57 0.08 -0.0697 -0.83 -0.9942 -0.983 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C02 mock treatment 0.089 -0.0554 -0.58 0.098 -0.0517 -0.62 -0.8494 -0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C03 mock treatment 0.089 -0.0554 -0.58 0.087 -0.0627 -0.75 -0.9424 -0.9921 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C04 mock treatment 0.197 0.0526 0.55 0.096 -0.0537 -0.64 -0.0642 -0.0758 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C05 mock treatment 0.089 -0.0554 -0.58 0.111 -0.0387 -0.46 -0.7394 -0.9936 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C06 mock treatment 0.227 0.0826 0.87 0.114 -0.0357 -0.43 0.3109 0.3215 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C07 mock treatment 0.208 0.0636 0.67 0.1 -0.0497 -0.6 0.0513 0.0574 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C08 mock treatment 0.092 -0.0524 -0.55 0.193 0.0433 0.52 -0.0234 -0.0309 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C09 mock treatment 0.106 -0.0384 -0.4 0.11 -0.0397 -0.48 -0.6216 -0.9967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C10 mock treatment 0.186 0.0416 0.44 0.104 -0.0457 -0.55 -0.0782 -0.1117 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C11 mock treatment 0.077 -0.0674 -0.71 0.099 -0.0507 -0.61 -0.93 -0.9971 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C12 mock treatment 0.089 -0.0554 -0.58 0.203 0.0533 0.64 0.039 0.0451 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C13 mock treatment 0.08 -0.0644 -0.68 0.094 -0.0557 -0.67 -0.95 -1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C14 mock treatment 0.074 -0.0704 -0.74 0.157 0.00726 0.09 -0.4616 -0.6198 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C15 mock treatment 0.07 -0.0744 -0.78 0.149 -7.35E-4 -0.01 -0.559 -0.715 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C16 mock treatment 0.208 0.0636 0.67 0.176 0.0263 0.31 0.6943 0.9409 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C17 mock treatment 0.158 0.0136 0.14 0.089 -0.0607 -0.73 -0.4131 -0.5578 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C18 mock treatment 0.095 -0.0494 -0.52 0.1 -0.0497 -0.6 -0.7879 -0.9977 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C19 mock treatment 0.187 0.0426 0.45 0.098 -0.0517 -0.62 -0.1216 -0.1592 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C20 mock treatment 0.083 -0.0614 -0.65 0.093 -0.0567 -0.68 -0.9362 -0.9997 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C21 mock treatment 0.161 0.0166 0.17 0.179 0.0293 0.35 0.3706 0.9479 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C22 mock treatment 0.089 -0.0554 -0.58 0.227 0.0773 0.92 0.242 0.2215 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C23 mock treatment 0.161 0.0166 0.17 0.175 0.0253 0.3 0.3368 0.9656 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base C24 mock treatment 0.096 -0.0484 -0.51 0.114 -0.0357 -0.43 -0.662 -0.9963 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D01 mock treatment 0.203 0.0586 0.62 0.084 -0.0657 -0.79 -0.1212 -0.1214 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D02 mock treatment 0.202 0.0576 0.6 0.091 -0.0587 -0.7 -0.0694 -0.0748 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D03 mock treatment 0.09 -0.0544 -0.57 0.093 -0.0567 -0.68 -0.8842 -0.9964 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D04 mock treatment 0.21 0.0656 0.69 0.23 0.0803 0.96 1.166 0.9867 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D05 mock treatment 0.244 0.0996 1.05 0.259 0.109 1.31 1.6638 0.9939 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D06 mock treatment 0.102 -0.0424 -0.45 0.111 -0.0387 -0.46 -0.6428 -0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D07 mock treatment 0.086 -0.0584 -0.61 0.1 -0.0497 -0.6 -0.8547 -0.9999 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D08 mock treatment 0.228 0.0836 0.88 0.103 -0.0467 -0.56 0.2252 0.2164 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D09 mock treatment 0.1 -0.0444 -0.47 0.191 0.0413 0.49 0.0191 0.0282 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D10 mock treatment 0.174 0.0296 0.31 0.099 -0.0507 -0.61 -0.2096 -0.3075 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D11 mock treatment 0.201 0.0566 0.59 0.19 0.0403 0.48 0.7607 0.9946 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D12 mock treatment 0.18 0.0356 0.37 0.095 -0.0547 -0.65 -0.1989 -0.2639 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D13 mock treatment 0.209 0.0646 0.68 0.103 -0.0467 -0.56 0.0841 0.0957 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D14 mock treatment 0.06 -0.0844 -0.89 0.103 -0.0467 -0.56 -1.0224 -0.9753 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D15 mock treatment 0.072 -0.0724 -0.76 0.115 -0.0347 -0.42 -0.8318 -0.9596 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D16 mock treatment 0.075 -0.0694 -0.73 0.183 0.0333 0.4 -0.2342 -0.2819 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D17 mock treatment 0.179 0.0346 0.36 0.107 -0.0427 -0.51 -0.1048 -0.1672 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D18 mock treatment 0.216 0.0716 0.75 0.111 -0.0387 -0.46 0.2038 0.2308 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D19 mock treatment 0.202 0.0576 0.6 0.181 0.0313 0.37 0.692 0.9734 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D20 mock treatment 0.081 -0.0634 -0.67 0.089 -0.0607 -0.73 -0.9849 -0.9991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D21 mock treatment 0.158 0.0136 0.14 0.196 0.0463 0.55 0.4922 0.8611 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D22 mock treatment 0.177 0.0326 0.34 0.085 -0.0647 -0.77 -0.3058 -0.3612 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D23 mock treatment 0.092 -0.0524 -0.55 0.166 0.0163 0.19 -0.2518 -0.4311 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base D24 mock treatment 0.137 -0.00743 -0.08 0.096 -0.0537 -0.64 -0.5098 -0.7872 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E01 mock treatment 0.098 -0.0464 -0.49 0.088 -0.0617 -0.74 -0.8671 -0.9797 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E02 mock treatment 0.089 -0.0554 -0.58 0.089 -0.0607 -0.73 -0.9255 -0.994 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E03 mock treatment 0.243 0.0986 1.04 0.218 0.0683 0.82 1.3095 0.9931 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E04 mock treatment 0.221 0.0766 0.8 0.242 0.0923 1.1 1.3492 0.9879 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E05 mock treatment 0.192 0.0476 0.5 0.112 -0.0377 -0.45 0.034 0.0505 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E06 mock treatment 0.231 0.0866 0.91 0.23 0.0803 0.96 1.3219 0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E07 mock treatment 0.08 -0.0644 -0.68 0.112 -0.0377 -0.45 -0.7978 -0.9806 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E08 mock treatment 0.258 0.114 1.19 0.183 0.0333 0.4 1.1248 0.8946 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E09 mock treatment 0.093 -0.0514 -0.54 0.206 0.0563 0.67 0.094 0.109 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E10 mock treatment 0.191 0.0466 0.49 0.125 -0.0247 -0.3 0.1366 0.2389 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E11 mock treatment 0.18 0.0356 0.37 0.117 -0.0327 -0.39 -0.0128 -0.0237 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E12 mock treatment 0.141 -0.00343 -0.04 0.114 -0.0357 -0.43 -0.3278 -0.764 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E13 mock treatment 0.185 0.0406 0.43 0.1 -0.0497 -0.6 -0.1195 -0.1633 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E14 mock treatment 0.177 0.0326 0.34 0.109 -0.0407 -0.49 -0.1028 -0.1726 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E15 mock treatment 0.066 -0.0784 -0.82 0.105 -0.0447 -0.54 -0.9609 -0.9782 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E16 mock treatment 0.208 0.0636 0.67 0.183 0.0333 0.4 0.7535 0.9694 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E17 mock treatment 0.178 0.0336 0.35 0.099 -0.0507 -0.61 -0.1799 -0.2563 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E18 mock treatment 0.185 0.0406 0.43 0.119 -0.0307 -0.37 0.0413 0.0733 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E19 mock treatment 0.067 -0.0774 -0.81 0.102 -0.0477 -0.57 -0.9789 -0.985 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E20 mock treatment 0.205 0.0606 0.64 0.113 -0.0367 -0.44 0.139 0.1798 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E21 mock treatment 0.081 -0.0634 -0.67 0.113 -0.0367 -0.44 -0.7819 -0.9796 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E22 mock treatment 0.083 -0.0614 -0.65 0.179 0.0293 0.35 -0.2086 -0.2842 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E23 mock treatment 0.076 -0.0684 -0.72 0.104 -0.0457 -0.55 -0.8951 -0.9909 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base E24 mock treatment 0.174 0.0296 0.31 0.094 -0.0557 -0.67 -0.2519 -0.3425 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F01 mock treatment 0.091 -0.0534 -0.56 0.092 -0.0577 -0.69 -0.8853 -0.9947 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F02 mock treatment 0.221 0.0766 0.8 0.246 0.0963 1.15 1.383 0.9846 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F03 mock treatment 0.105 -0.0394 -0.41 0.253 0.103 1.24 0.5808 0.4457 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F04 mock treatment 0.081 -0.0634 -0.67 0.098 -0.0517 -0.62 -0.9088 -0.9993 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F05 mock treatment 0.091 -0.0534 -0.56 0.255 0.105 1.26 0.4937 0.3581 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F06 mock treatment 0.081 -0.0634 -0.67 0.216 0.0663 0.79 0.0895 0.0865 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F07 mock treatment 0.229 0.0846 0.89 0.224 0.0743 0.89 1.2563 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F08 mock treatment 0.205 0.0606 0.64 0.101 -0.0487 -0.58 0.0375 0.0435 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F09 mock treatment 0.181 0.0366 0.38 0.123 -0.0267 -0.32 0.0454 0.0908 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F10 mock treatment 0.19 0.0456 0.48 0.108 -0.0417 -0.5 -0.0147 -0.0212 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F11 mock treatment 0.211 0.0666 0.7 0.113 -0.0367 -0.44 0.1836 0.2223 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F12 mock treatment 0.197 0.0526 0.55 0.164 0.0143 0.17 0.5111 0.8844 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F13 mock treatment 0.068 -0.0764 -0.8 0.175 0.0253 0.3 -0.3539 -0.4126 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F14 mock treatment 0.191 0.0466 0.49 0.189 0.0393 0.47 0.678 0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F15 mock treatment 0.083 -0.0614 -0.65 0.115 -0.0347 -0.42 -0.7501 -0.9774 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F16 mock treatment 0.066 -0.0784 -0.82 0.093 -0.0567 -0.68 -1.0625 -0.9954 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F17 mock treatment 0.076 -0.0684 -0.72 0.186 0.0363 0.43 -0.2014 -0.2399 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F18 mock treatment 0.075 -0.0694 -0.73 0.098 -0.0517 -0.62 -0.9533 -0.9967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F19 mock treatment 0.177 0.0326 0.34 0.111 -0.0387 -0.46 -0.0858 -0.149 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F20 mock treatment 0.087 -0.0574 -0.6 0.1 -0.0497 -0.6 -0.8473 -1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F21 mock treatment 0.084 -0.0604 -0.63 0.127 -0.0227 -0.27 -0.6411 -0.9285 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F22 mock treatment 0.073 -0.0714 -0.75 0.148 -0.00174 -0.02 -0.5452 -0.7264 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F23 mock treatment 0.086 -0.0584 -0.61 0.116 -0.0337 -0.4 -0.7194 -0.9793 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base F24 mock treatment 0.085 -0.0594 -0.62 0.102 -0.0477 -0.57 -0.8452 -0.999 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G01 mock treatment 0.106 -0.0384 -0.4 0.077 -0.0727 -0.87 -0.9008 -0.939 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G02 mock treatment 0.187 0.0426 0.45 0.091 -0.0587 -0.7 -0.1808 -0.217 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G03 mock treatment 0.189 0.0446 0.47 0.106 -0.0437 -0.52 -0.039 -0.0556 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G04 mock treatment 0.206 0.0616 0.65 0.227 0.0773 0.92 1.1109 0.9847 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G05 mock treatment 0.086 -0.0584 -0.61 0.118 -0.0317 -0.38 -0.7024 -0.9734 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G06 mock treatment 0.103 -0.0414 -0.44 0.095 -0.0547 -0.65 -0.7708 -0.9803 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G07 mock treatment 0.218 0.0736 0.77 0.107 -0.0427 -0.51 0.1848 0.1995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G08 mock treatment 0.125 -0.0194 -0.2 0.108 -0.0417 -0.5 -0.4974 -0.9221 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G09 mock treatment 0.184 0.0396 0.42 0.195 0.0453 0.54 0.6768 0.9914 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G10 mock treatment 0.226 0.0816 0.86 0.206 0.0563 0.67 1.0818 0.9929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G11 mock treatment 0.219 0.0746 0.78 0.104 -0.0457 -0.55 0.1668 0.1746 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G12 mock treatment 0.157 0.0126 0.13 0.118 -0.0317 -0.38 -0.1752 -0.4357 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G13 mock treatment 0.186 0.0416 0.44 0.171 0.0213 0.25 0.4886 0.967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G14 mock treatment 0.205 0.0606 0.64 0.189 0.0393 0.47 0.782 0.9889 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G15 mock treatment 0.207 0.0626 0.66 0.196 0.0463 0.55 0.8561 0.9964 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G16 mock treatment 0.068 -0.0764 -0.8 0.207 0.0573 0.69 -0.0832 -0.0788 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G17 mock treatment 0.074 -0.0704 -0.74 0.105 -0.0447 -0.54 -0.9015 -0.9874 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G18 mock treatment 0.071 -0.0734 -0.77 0.201 0.0513 0.61 -0.1116 -0.1133 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G19 mock treatment 0.074 -0.0704 -0.74 0.106 -0.0437 -0.52 -0.8931 -0.9856 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G20 mock treatment 0.186 0.0416 0.44 0.171 0.0213 0.25 0.4886 0.967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G21 mock treatment 0.079 -0.0654 -0.69 0.107 -0.0427 -0.51 -0.8475 -0.9894 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G22 mock treatment 0.172 0.0276 0.29 0.126 -0.0237 -0.28 0.0039 0.0097 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G23 mock treatment 0.15 0.00557 0.06 0.093 -0.0567 -0.68 -0.4386 -0.6438 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base G24 mock treatment 0.153 0.00857 0.09 0.154 0.00426 0.05 0.0997 0.9639 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H01 mock treatment 0.213 0.0686 0.72 0.09 -0.0597 -0.71 0.0038 0.0038 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H02 mock treatment 0.084 -0.0604 -0.63 0.087 -0.0627 -0.75 -0.9796 -0.9965 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H03 mock treatment 0.206 0.0616 0.65 0.107 -0.0427 -0.51 0.0957 0.1161 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H04 mock treatment 0.096 -0.0484 -0.51 0.201 0.0513 0.61 0.074 0.0929 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H05 mock treatment 0.185 0.0406 0.43 0.209 0.0593 0.71 0.8027 0.9703 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H06 mock treatment 0.109 -0.0354 -0.37 0.239 0.0893 1.07 0.4921 0.4351 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H07 mock treatment 0.134 -0.0104 -0.11 0.112 -0.0377 -0.45 -0.3967 -0.8539 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H08 mock treatment 0.182 0.0376 0.39 0.1 -0.0497 -0.6 -0.1418 -0.1986 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H09 mock treatment 0.164 0.0196 0.21 0.167 0.0173 0.21 0.2914 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H10 mock treatment 0.279 0.135 1.41 0.107 -0.0427 -0.51 0.6378 0.4244 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H11 mock treatment 0.166 0.0216 0.23 0.227 0.0773 0.92 0.8138 0.8551 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H12 mock treatment 0.3 0.156 1.63 0.125 -0.0247 -0.3 0.9461 0.5698 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H13 mock treatment 0.203 0.0586 0.62 0.107 -0.0427 -0.51 0.0734 0.0918 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H14 mock treatment 0.2 0.0556 0.58 0.179 0.0293 0.35 0.6603 0.9701 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H15 mock treatment 0.235 0.0906 0.95 0.119 -0.0307 -0.37 0.4126 0.4046 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H16 mock treatment 0.2 0.0556 0.58 0.178 0.0283 0.34 0.6518 0.9663 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H17 mock treatment 0.069 -0.0754 -0.79 0.107 -0.0427 -0.51 -0.9217 -0.9776 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H18 mock treatment 0.081 -0.0634 -0.67 0.116 -0.0337 -0.4 -0.7565 -0.9712 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H19 mock treatment 0.189 0.0446 0.47 0.224 0.0743 0.89 0.9593 0.9552 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H20 mock treatment 0.056 -0.0884 -0.93 0.106 -0.0437 -0.52 -1.0267 -0.9631 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H21 mock treatment 0.08 -0.0644 -0.68 0.165 0.0153 0.18 -0.3494 -0.4984 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H22 mock treatment 0.079 -0.0654 -0.69 0.168 0.0183 0.22 -0.3314 -0.4596 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H23 mock treatment 0.166 0.0216 0.23 0.162 0.0123 0.15 0.2639 0.9779 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base H24 mock treatment 0.085 -0.0594 -0.62 0.146 -0.00374 -0.04 -0.473 -0.7558 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I01 mock treatment 0.12 -0.0244 -0.26 0.079 -0.0707 -0.85 -0.7799 -0.8819 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I02 mock treatment 0.093 -0.0514 -0.54 0.248 0.0983 1.18 0.4494 0.3473 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I03 mock treatment 0.122 -0.0224 -0.24 0.109 -0.0407 -0.49 -0.5112 -0.9444 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I04 mock treatment 0.091 -0.0534 -0.56 0.109 -0.0407 -0.49 -0.7414 -0.9975 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I05 mock treatment 0.217 0.0726 0.76 0.13 -0.0197 -0.24 0.372 0.4662 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I06 mock treatment 0.095 -0.0494 -0.52 0.109 -0.0407 -0.49 -0.7117 -0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I07 mock treatment 0.088 -0.0564 -0.59 0.181 0.0313 0.37 -0.1546 -0.2206 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I08 mock treatment 0.112 -0.0324 -0.34 0.238 0.0883 1.06 0.5059 0.4559 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I09 mock treatment 0.077 -0.0674 -0.71 0.215 0.0653 0.78 0.0514 0.0487 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I10 mock treatment 0.207 0.0626 0.66 0.224 0.0743 0.89 1.0929 0.989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I11 mock treatment 0.175 0.0306 0.32 0.238 0.0883 1.06 0.9737 0.8822 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I12 mock treatment 0.366 0.222 2.33 0.255 0.105 1.26 2.536 0.9584 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I13 mock treatment 0.088 -0.0564 -0.59 0.116 -0.0337 -0.4 -0.7045 -0.9825 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I14 mock treatment 0.087 -0.0574 -0.6 0.211 0.0613 0.73 0.0918 0.0967 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I15 mock treatment 0.237 0.0926 0.97 0.203 0.0533 0.64 1.1381 0.979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I16 mock treatment 0.104 -0.0404 -0.42 0.12 -0.0297 -0.36 -0.5518 -0.9961 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I17 mock treatment 0.182 0.0376 0.39 0.119 -0.0307 -0.37 0.019 0.0352 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I18 mock treatment 0.224 0.0796 0.84 0.102 -0.0477 -0.57 0.1871 0.1848 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I19 mock treatment 0.203 0.0586 0.62 0.188 0.0383 0.46 0.7587 0.9894 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I20 mock treatment 0.218 0.0736 0.77 0.124 -0.0257 -0.31 0.3286 0.3951 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I21 mock treatment 0.073 -0.0714 -0.75 0.097 -0.0527 -0.63 -0.9766 -0.9963 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I22 mock treatment 0.167 0.0226 0.24 0.108 -0.0417 -0.5 -0.1855 -0.3356 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I23 mock treatment 0.082 -0.0624 -0.66 0.151 0.00126 0.02 -0.453 -0.6906 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base I24 mock treatment 0.1 -0.0444 -0.47 0.162 0.0123 0.15 -0.2262 -0.4624 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J01 mock treatment 0.096 -0.0484 -0.51 0.224 0.0743 0.89 0.2686 0.2624 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J02 mock treatment 0.088 -0.0564 -0.59 0.177 0.0273 0.33 -0.1884 -0.2785 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J03 mock treatment 0.119 -0.0254 -0.27 0.113 -0.0367 -0.44 -0.4997 -0.9715 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J04 mock treatment 0.123 -0.0214 -0.23 0.143 -0.00674 -0.08 -0.2161 -0.9041 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J05 mock treatment 0.215 0.0706 0.74 0.112 -0.0377 -0.45 0.2048 0.236 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J06 mock treatment 0.19 0.0456 0.48 0.117 -0.0327 -0.39 0.0615 0.0994 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J07 mock treatment 0.241 0.0966 1.01 0.116 -0.0337 -0.4 0.4318 0.3955 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J08 mock treatment 0.221 0.0766 0.8 0.21 0.0603 0.72 1.0785 0.9985 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J09 mock treatment 0.171 0.0266 0.28 0.238 0.0883 1.06 0.944 0.8643 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J10 mock treatment 0.17 0.0256 0.27 0.206 0.0563 0.67 0.6659 0.9188 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J11 mock treatment 0.217 0.0726 0.76 0.252 0.102 1.22 1.4041 0.9741 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J12 mock treatment 0.123 -0.0214 -0.23 0.189 0.0393 0.47 0.173 0.3321 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J13 mock treatment 0.068 -0.0764 -0.8 0.242 0.0923 1.1 0.2129 0.156 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J14 mock treatment 0.086 -0.0584 -0.61 0.136 -0.0137 -0.16 -0.5502 -0.8659 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J15 mock treatment 0.237 0.0926 0.97 0.135 -0.0147 -0.18 0.5628 0.5696 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J16 mock treatment 0.092 -0.0524 -0.55 0.211 0.0613 0.73 0.1289 0.1406 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J17 mock treatment 0.227 0.0826 0.87 0.245 0.0953 1.14 1.4191 0.9909 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J18 mock treatment 0.209 0.0646 0.68 0.221 0.0713 0.85 1.0824 0.9936 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J19 mock treatment 0.075 -0.0694 -0.73 0.12 -0.0297 -0.36 -0.7672 -0.9456 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J20 mock treatment 0.078 -0.0664 -0.7 0.104 -0.0457 -0.55 -0.8803 -0.9928 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J21 mock treatment 0.167 0.0226 0.24 0.112 -0.0377 -0.45 -0.1516 -0.2974 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J22 mock treatment 0.079 -0.0654 -0.69 0.17 0.0203 0.24 -0.3145 -0.4316 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J23 mock treatment 0.185 0.0406 0.43 0.192 0.0423 0.51 0.6588 0.9964 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base J24 mock treatment 0.155 0.0106 0.11 0.139 -0.0107 -0.13 -0.0123 -0.0727 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K01 mock treatment 0.18 0.0356 0.37 0.084 -0.0657 -0.79 -0.292 -0.3353 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K02 mock treatment 0.186 0.0416 0.44 0.205 0.0553 0.66 0.7763 0.9797 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K03 mock treatment 0.22 0.0756 0.79 0.2 0.0503 0.6 0.9865 0.9906 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K04 mock treatment 0.218 0.0736 0.77 0.26 0.11 1.32 1.4792 0.9675 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K05 mock treatment 0.182 0.0376 0.39 0.204 0.0543 0.65 0.7381 0.9715 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K06 mock treatment 0.212 0.0676 0.71 0.115 -0.0347 -0.42 0.2079 0.2528 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K07 mock treatment 0.206 0.0616 0.65 0.108 -0.0417 -0.5 0.1041 0.1275 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K08 mock treatment 0.217 0.0726 0.76 0.184 0.0343 0.41 0.8288 0.9577 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K09 mock treatment 0.207 0.0626 0.66 0.195 0.0453 0.54 0.8476 0.9954 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K10 mock treatment 0.217 0.0726 0.76 0.184 0.0343 0.41 0.8288 0.9577 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K11 mock treatment 0.188 0.0436 0.46 0.126 -0.0237 -0.28 0.1228 0.2279 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K12 mock treatment 0.21 0.0656 0.69 0.204 0.0543 0.65 0.946 0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K13 mock treatment 0.214 0.0696 0.73 0.112 -0.0377 -0.45 0.1974 0.2298 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K14 mock treatment 0.229 0.0846 0.89 0.108 -0.0417 -0.5 0.275 0.2698 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K15 mock treatment 0.223 0.0786 0.83 0.123 -0.0267 -0.32 0.3573 0.4037 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K16 mock treatment 0.207 0.0626 0.66 0.124 -0.0257 -0.31 0.2469 0.3403 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K17 mock treatment 0.187 0.0426 0.45 0.115 -0.0347 -0.42 0.0223 0.0365 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K18 mock treatment 0.076 -0.0684 -0.72 0.264 0.114 1.37 0.4585 0.2968 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K19 mock treatment 0.07 -0.0744 -0.78 0.106 -0.0437 -0.52 -0.9228 -0.9809 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K20 mock treatment 0.075 -0.0694 -0.73 0.112 -0.0377 -0.45 -0.8349 -0.9734 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K21 mock treatment 0.093 -0.0514 -0.54 0.102 -0.0477 -0.57 -0.7858 -0.9996 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K22 mock treatment 0.101 -0.0434 -0.46 0.176 0.0263 0.31 -0.1003 -0.1812 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K23 mock treatment 0.083 -0.0614 -0.65 0.145 -0.00474 -0.06 -0.4963 -0.7663 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base K24 mock treatment 0.081 -0.0634 -0.67 0.103 -0.0467 -0.56 -0.8665 -0.9962 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L01 mock treatment 0.094 -0.0504 -0.53 0.088 -0.0617 -0.74 -0.8968 -0.9867 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L02 mock treatment 0.164 0.0196 0.21 0.223 0.0733 0.88 0.7651 0.8498 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L03 mock treatment 0.219 0.0746 0.78 0.125 -0.0247 -0.3 0.3445 0.4115 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L04 mock treatment 0.084 -0.0604 -0.63 0.229 0.0793 0.95 0.2218 0.1944 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L05 mock treatment 0.215 0.0706 0.74 0.102 -0.0477 -0.57 0.1202 0.1285 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L06 mock treatment 0.185 0.0406 0.43 0.213 0.0633 0.76 0.8365 0.963 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L07 mock treatment 0.225 0.0806 0.85 0.189 0.0393 0.47 0.9305 0.9614 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L08 mock treatment 0.201 0.0566 0.59 0.169 0.0193 0.23 0.5831 0.915 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L09 mock treatment 0.137 -0.00743 -0.08 0.196 0.0463 0.55 0.3362 0.6014 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L10 mock treatment 0.127 -0.0174 -0.18 0.19 0.0403 0.48 0.2112 0.4098 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L11 mock treatment 0.225 0.0806 0.85 0.192 0.0423 0.51 0.9559 0.9697 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L12 mock treatment 0.166 0.0216 0.23 0.114 -0.0357 -0.43 -0.1422 -0.2938 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L13 mock treatment 0.208 0.0636 0.67 0.104 -0.0457 -0.55 0.0852 0.0987 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L14 mock treatment 0.074 -0.0704 -0.74 0.11 -0.0397 -0.48 -0.8592 -0.9772 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L15 mock treatment 0.202 0.0576 0.6 0.143 -0.00674 -0.08 0.3705 0.6075 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L16 mock treatment 0.203 0.0586 0.62 0.12 -0.0297 -0.36 0.1834 0.2581 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L17 mock treatment 0.077 -0.0674 -0.71 0.203 0.0533 0.64 -0.0502 -0.0526 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L18 mock treatment 0.071 -0.0734 -0.77 0.217 0.0673 0.8 0.0237 0.0213 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L19 mock treatment 0.177 0.0326 0.34 0.116 -0.0337 -0.4 -0.0435 -0.0823 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L20 mock treatment 0.186 0.0416 0.44 0.095 -0.0547 -0.65 -0.1544 -0.1961 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L21 mock treatment 0.214 0.0696 0.73 0.112 -0.0377 -0.45 0.1974 0.2298 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L22 mock treatment 0.164 0.0196 0.21 0.182 0.0323 0.39 0.4183 0.9565 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L23 mock treatment 0.146 0.00157 0.02 0.172 0.0223 0.27 0.2 0.7494 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base L24 mock treatment 0.08 -0.0644 -0.68 0.164 0.0143 0.17 -0.3578 -0.5127 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M01 mock treatment 0.213 0.0686 0.72 0.094 -0.0557 -0.67 0.0377 0.0384 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M02 mock treatment 0.223 0.0786 0.83 0.224 0.0743 0.89 1.2118 0.9993 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M03 mock treatment 0.192 0.0476 0.5 0.199 0.0493 0.59 0.77 0.9966 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M04 mock treatment 0.214 0.0696 0.73 0.134 -0.0157 -0.19 0.3835 0.5083 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M05 mock treatment 0.254 0.11 1.15 0.192 0.0423 0.51 1.1713 0.9318 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M06 mock treatment 0.211 0.0666 0.7 0.217 0.0673 0.8 1.0634 0.9975 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M07 mock treatment 0.208 0.0636 0.67 0.197 0.0473 0.57 0.872 0.9966 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M08 mock treatment 0.226 0.0816 0.86 0.154 0.00426 0.05 0.6418 0.7479 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M09 mock treatment 0.133 -0.0114 -0.12 0.111 -0.0387 -0.46 -0.4126 -0.8618 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M10 mock treatment 0.238 0.0936 0.98 0.208 0.0583 0.7 1.1878 0.9859 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M11 mock treatment 0.159 0.0146 0.15 0.198 0.0483 0.58 0.5165 0.8646 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M12 mock treatment 0.189 0.0446 0.47 0.116 -0.0337 -0.4 0.0456 0.0737 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M13 mock treatment 0.074 -0.0704 -0.74 0.178 0.0283 0.34 -0.2839 -0.3491 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M14 mock treatment 0.204 0.0596 0.63 0.203 0.0533 0.64 0.893 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M15 mock treatment 0.204 0.0596 0.63 0.166 0.0163 0.19 0.58 0.8852 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M16 mock treatment 0.194 0.0496 0.52 0.118 -0.0317 -0.38 0.0996 0.1546 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M17 mock treatment 0.168 0.0236 0.25 0.181 0.0313 0.37 0.4395 0.9799 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M18 mock treatment 0.071 -0.0734 -0.77 0.113 -0.0367 -0.44 -0.8561 -0.9645 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M19 mock treatment 0.183 0.0386 0.41 0.11 -0.0397 -0.48 -0.0497 -0.0796 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M20 mock treatment 0.084 -0.0604 -0.63 0.1 -0.0497 -0.6 -0.8696 -0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M21 mock treatment 0.082 -0.0624 -0.66 0.163 0.0133 0.16 -0.3514 -0.5209 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M22 mock treatment 0.081 -0.0634 -0.67 0.186 0.0363 0.43 -0.1643 -0.2066 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M23 mock treatment 0.082 -0.0624 -0.66 0.1 -0.0497 -0.6 -0.8844 -0.9988 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base M24 mock treatment 0.143 -0.00143 -0.02 0.153 0.00326 0.04 0.017 0.4058 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N01 mock treatment 0.077 -0.0674 -0.71 0.248 0.0983 1.18 0.3305 0.2408 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N02 mock treatment 0.194 0.0496 0.52 0.223 0.0733 0.88 0.9879 0.969 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N03 mock treatment 0.08 -0.0644 -0.68 0.091 -0.0587 -0.7 -0.9754 -0.9998 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N04 mock treatment 0.118 -0.0264 -0.28 0.218 0.0683 0.82 0.3812 0.4419 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N05 mock treatment 0.107 -0.0374 -0.39 0.098 -0.0517 -0.62 -0.7157 -0.976 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N06 mock treatment 0.184 0.0396 0.42 0.104 -0.0457 -0.55 -0.0931 -0.1355 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N07 mock treatment 0.089 -0.0554 -0.58 0.208 0.0583 0.7 0.0813 0.0895 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N08 mock treatment 0.1 -0.0444 -0.47 0.229 0.0793 0.95 0.3406 0.3223 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N09 mock treatment 0.159 0.0146 0.15 0.116 -0.0337 -0.4 -0.1772 -0.4106 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N10 mock treatment 0.111 -0.0334 -0.35 0.222 0.0723 0.86 0.3631 0.3891 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N11 mock treatment 0.104 -0.0404 -0.42 0.185 0.0353 0.42 -0.0019 -0.0032 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N12 mock treatment 0.079 -0.0654 -0.69 0.17 0.0203 0.24 -0.3145 -0.4316 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N13 mock treatment 0.199 0.0546 0.57 0.232 0.0823 0.98 1.1012 0.9669 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N14 mock treatment 0.068 -0.0764 -0.8 0.107 -0.0427 -0.51 -0.9292 -0.9763 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N15 mock treatment 0.179 0.0346 0.36 0.109 -0.0407 -0.49 -0.0879 -0.1447 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N16 mock treatment 0.063 -0.0814 -0.86 0.201 0.0513 0.61 -0.171 -0.1625 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N17 mock treatment 0.198 0.0536 0.56 0.173 0.0233 0.28 0.5946 0.9473 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N18 mock treatment 0.067 -0.0774 -0.81 0.158 0.00826 0.1 -0.5051 -0.6166 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N19 mock treatment 0.16 0.0156 0.16 0.113 -0.0367 -0.44 -0.1952 -0.4162 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N20 mock treatment 0.181 0.0366 0.38 0.114 -0.0357 -0.43 -0.0308 -0.0535 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N21 mock treatment 0.065 -0.0794 -0.83 0.114 -0.0357 -0.43 -0.8922 -0.9518 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N22 mock treatment 0.071 -0.0734 -0.77 0.106 -0.0437 -0.52 -0.9154 -0.9821 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N23 mock treatment 0.085 -0.0594 -0.62 0.165 0.0153 0.18 -0.3122 -0.4801 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base N24 mock treatment 0.141 -0.00343 -0.04 0.15 2.65E-4 0.0 -0.0233 -0.6425 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O01 mock treatment 0.082 -0.0624 -0.66 0.2 0.0503 0.6 -0.0384 -0.0432 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O02 mock treatment 0.087 -0.0574 -0.6 0.096 -0.0537 -0.64 -0.8811 -0.9995 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O03 mock treatment 0.085 -0.0594 -0.62 0.203 0.0533 0.64 0.0093 0.0104 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O04 mock treatment 0.097 -0.0474 -0.5 0.097 -0.0527 -0.63 -0.7984 -0.9932 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O05 mock treatment 0.183 0.0386 0.41 0.085 -0.0647 -0.77 -0.2612 -0.2989 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O06 mock treatment 0.219 0.0746 0.78 0.106 -0.0437 -0.52 0.1838 0.1951 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O07 mock treatment 0.194 0.0496 0.52 0.089 -0.0607 -0.73 -0.1457 -0.163 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O08 mock treatment 0.224 0.0796 0.84 0.214 0.0643 0.77 1.1346 0.9991 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O09 mock treatment 0.191 0.0466 0.49 0.093 -0.0567 -0.68 -0.1342 -0.1603 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O10 mock treatment 0.207 0.0626 0.66 0.109 -0.0407 -0.49 0.12 0.1467 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O11 mock treatment 0.218 0.0736 0.77 0.106 -0.0437 -0.52 0.1763 0.189 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O12 mock treatment 0.087 -0.0574 -0.6 0.2 0.0503 0.6 -0.0013 -0.0015 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O13 mock treatment 0.075 -0.0694 -0.73 0.182 0.0323 0.39 -0.2427 -0.2941 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O14 mock treatment 0.077 -0.0674 -0.71 0.09 -0.0597 -0.71 -1.0062 -1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O15 mock treatment 0.185 0.0406 0.43 0.197 0.0473 0.57 0.7011 0.9903 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O16 mock treatment 0.075 -0.0694 -0.73 0.193 0.0433 0.52 -0.1496 -0.1673 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O17 mock treatment 0.067 -0.0774 -0.81 0.228 0.0783 0.94 0.0871 0.0702 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O18 mock treatment 0.193 0.0486 0.51 0.176 0.0263 0.31 0.5829 0.9729 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O19 mock treatment 0.165 0.0206 0.22 0.094 -0.0557 -0.67 -0.3188 -0.4548 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O20 mock treatment 0.155 0.0106 0.11 0.086 -0.0637 -0.76 -0.4607 -0.5979 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O21 mock treatment 0.184 0.0396 0.42 0.203 0.0533 0.64 0.7445 0.9785 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O22 mock treatment 0.14 -0.00443 -0.05 0.157 0.00726 0.09 0.0285 0.2895 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O23 mock treatment 0.136 -0.00843 -0.09 0.206 0.0563 0.67 0.4134 0.6088 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base O24 mock treatment 0.088 -0.0564 -0.59 0.086 -0.0637 -0.76 -0.9583 -0.9922 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P01 mock treatment 0.084 -0.0604 -0.63 0.231 0.0813 0.97 0.2387 0.2056 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P02 mock treatment 0.101 -0.0434 -0.46 0.103 -0.0467 -0.56 -0.7179 -0.9949 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P03 mock treatment 0.085 -0.0594 -0.62 0.219 0.0693 0.83 0.1446 0.1394 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P04 mock treatment 0.174 0.0296 0.31 0.084 -0.0657 -0.79 -0.3365 -0.398 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P05 mock treatment 0.092 -0.0524 -0.55 0.097 -0.0527 -0.63 -0.8355 -0.9977 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P06 mock treatment 0.181 0.0366 0.38 0.217 0.0673 0.8 0.8406 0.9427 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P07 mock treatment 0.221 0.0766 0.8 0.1 -0.0497 -0.6 0.1479 0.1478 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P08 mock treatment 0.18 0.0356 0.37 0.155 0.00526 0.06 0.3087 0.8148 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P09 mock treatment 0.194 0.0496 0.52 0.193 0.0433 0.52 0.7341 1.0 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P10 mock treatment 0.079 -0.0654 -0.69 0.099 -0.0507 -0.61 -0.9152 -0.9981 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P11 mock treatment 0.106 -0.0384 -0.4 0.178 0.0283 0.34 -0.0463 -0.0879 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P12 mock treatment 0.078 -0.0664 -0.7 0.202 0.0523 0.63 -0.0512 -0.0546 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P13 mock treatment 0.074 -0.0704 -0.74 0.09 -0.0597 -0.71 -1.0284 -0.9999 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P14 mock treatment 0.074 -0.0704 -0.74 0.188 0.0383 0.46 -0.1993 -0.2291 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P15 mock treatment 0.079 -0.0654 -0.69 0.166 0.0163 0.19 -0.3483 -0.4877 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P16 mock treatment 0.079 -0.0654 -0.69 0.142 -0.00774 -0.09 -0.5514 -0.7952 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P17 mock treatment 0.069 -0.0754 -0.79 0.155 0.00526 0.06 -0.5157 -0.6488 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P18 mock treatment 0.072 -0.0724 -0.76 0.153 0.00326 0.04 -0.5103 -0.6699 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P19 mock treatment 0.178 0.0336 0.35 0.092 -0.0577 -0.69 -0.2392 -0.3084 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P20 mock treatment 0.07 -0.0744 -0.78 0.094 -0.0557 -0.67 -1.0243 -0.9969 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P21 mock treatment 0.172 0.0276 0.29 0.091 -0.0587 -0.7 -0.2922 -0.3844 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P22 mock treatment 0.164 0.0196 0.21 0.087 -0.0627 -0.75 -0.3854 -0.4953 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P23 mock treatment 0.09 -0.0544 -0.57 0.093 -0.0567 -0.68 -0.8842 -0.9964 1091.0042 OpticalDensity(1091.0042) PDERegulators 1091.0042.Base P24 mock treatment 0.081 -0.0634 -0.67 0.082 -0.0677 -0.81 -1.0441 -0.9953