ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A01 compound treatment 4.62822011E8 -2.19E7 -0.34 5.41862221E8 5020000.0 0.11 -0.1611 -0.4479 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A02 compound treatment 4.64053473E8 -2.07E7 -0.32 5.71287625E8 3.44E7 0.78 0.3227 0.383 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A03 compound treatment 4.21687428E8 -6.31E7 -0.98 4.84352548E8 -5.25E7 -1.19 -1.5332 -0.9956 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A04 compound treatment 4.60110845E8 -2.46E7 -0.38 5.38165361E8 1320000.0 0.03 -0.2501 -0.65 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A05 compound treatment 4.3559347E8 -4.91E7 -0.77 5.2022108E8 -1.66E7 -0.38 -0.8069 -0.9463 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A06 compound treatment 4.32132175E8 -5.26E7 -0.82 5.24116682E8 -1.27E7 -0.29 -0.7827 -0.9014 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A07 compound treatment 4.29763999E8 -5.5E7 -0.86 4.85389764E8 -5.15E7 -1.16 -1.4277 -0.9887 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A08 compound treatment 4.68779882E8 -1.6E7 -0.25 5.1152901E8 -2.53E7 -0.57 -0.5803 -0.9303 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A09 compound treatment 4.20742784E8 -6.4E7 -1.0 5.19768245E8 -1.71E7 -0.39 -0.9777 -0.9147 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A10 compound treatment 4.71092562E8 -1.36E7 -0.21 5.17497861E8 -1.93E7 -0.44 -0.4594 -0.9451 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A11 compound treatment 4.09452186E8 -7.53E7 -1.17 4.36642793E8 -1.0E8 -2.26 -2.4304 -0.9531 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A12 compound treatment 4.63601369E8 -2.11E7 -0.33 5.05713943E8 -3.11E7 -0.7 -0.7302 -0.9402 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A13 mock treatment 4.69304258E8 -1.54E7 -0.24 4.94537311E8 -4.23E7 -0.96 -0.846 -0.8582 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A14 mock treatment 4.52299213E8 -3.24E7 -0.51 4.97755531E8 -3.91E7 -0.88 -0.9819 -0.9649 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A15 compound treatment 4.32884612E8 -5.19E7 -0.81 4.746246E8 -6.22E7 -1.41 -1.5654 -0.9654 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A16 compound treatment 4.20206741E8 -6.45E7 -1.01 4.76152377E8 -6.07E7 -1.37 -1.6806 -0.9883 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A17 compound treatment 4.38855023E8 -4.59E7 -0.71 4.89266282E8 -4.76E7 -1.08 -1.2656 -0.9803 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A18 compound treatment 4.21348563E8 -6.34E7 -0.99 4.72675165E8 -6.42E7 -1.45 -1.7236 -0.9824 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A19 compound treatment 4.44887165E8 -3.99E7 -0.62 4.80138471E8 -5.67E7 -1.28 -1.3451 -0.9446 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A20 compound treatment 4.28740691E8 -5.6E7 -0.87 4.75236096E8 -6.16E7 -1.39 -1.6012 -0.9746 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A21 compound treatment 4.2272435E8 -6.2E7 -0.97 4.52396296E8 -8.44E7 -1.91 -2.0325 -0.9502 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A22 compound treatment 4.36274343E8 -4.85E7 -0.75 4.88270169E8 -4.86E7 -1.1 -1.31 -0.9833 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A23 compound treatment 3.68759003E8 -1.16E8 -1.81 4.03353732E8 -1.33E8 -3.02 -3.4106 -0.9699 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 A24 compound treatment 4.18130254E8 -6.66E7 -1.04 4.67826513E8 -6.9E7 -1.56 -1.8365 -0.9804 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B01 compound treatment 4.28224975E8 -5.65E7 -0.88 5.10330586E8 -2.65E7 -0.6 -1.0461 -0.9824 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B02 compound treatment 4.33613672E8 -5.11E7 -0.8 4.77179124E8 -5.97E7 -1.35 -1.5165 -0.9684 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B03 compound treatment 4.28978707E8 -5.58E7 -0.87 4.88983794E8 -4.79E7 -1.08 -1.3789 -0.9941 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B04 compound treatment 4.15486735E8 -6.93E7 -1.08 4.7354837E8 -6.33E7 -1.43 -1.7742 -0.9903 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B05 compound treatment 4.5744598E8 -2.73E7 -0.43 5.13386576E8 -2.35E7 -0.53 -0.6754 -0.994 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B06 compound treatment 4.23295329E8 -6.14E7 -0.96 4.76931613E8 -5.99E7 -1.35 -1.6341 -0.9856 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B07 compound treatment 4.14998395E8 -6.97E7 -1.09 4.822987E8 -5.45E7 -1.23 -1.6397 -0.998 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B08 compound treatment 4.22667727E8 -6.21E7 -0.97 4.79390019E8 -5.75E7 -1.3 -1.6017 -0.9895 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B09 compound treatment 4.17562225E8 -6.72E7 -1.05 4.74368554E8 -6.25E7 -1.41 -1.7382 -0.9891 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B10 compound treatment 4.34343795E8 -5.04E7 -0.78 4.76637418E8 -6.02E7 -1.36 -1.5171 -0.9658 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B11 compound treatment 4.40114393E8 -4.46E7 -0.7 4.80790967E8 -5.61E7 -1.27 -1.3872 -0.9601 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B12 compound treatment 4.37491645E8 -4.72E7 -0.74 4.60192563E8 -7.66E7 -1.73 -1.7453 -0.9273 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B13 mock treatment 4.68701431E8 -1.6E7 -0.25 5.01567629E8 -3.53E7 -0.8 -0.7403 -0.8862 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B14 mock treatment 4.53513718E8 -3.12E7 -0.49 5.01783747E8 -3.51E7 -0.79 -0.9041 -0.9725 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B15 compound treatment 4.31332122E8 -5.34E7 -0.83 4.92809825E8 -4.4E7 -1.0 -1.2919 -0.996 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B16 compound treatment 4.3582262E8 -4.89E7 -0.76 4.47717898E8 -8.91E7 -2.01 -1.963 -0.9115 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B17 compound treatment 4.3034595E8 -5.44E7 -0.85 4.78492512E8 -5.83E7 -1.32 -1.5315 -0.9771 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B18 compound treatment 4.45097279E8 -3.96E7 -0.62 4.69836305E8 -6.7E7 -1.51 -1.5074 -0.9217 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B19 compound treatment 4.36041966E8 -4.87E7 -0.76 5.01580499E8 -3.53E7 -0.8 -1.0998 -0.9997 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B20 compound treatment 4.1181101E8 -7.29E7 -1.14 4.74752347E8 -6.21E7 -1.4 -1.7954 -0.9945 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B21 compound treatment 4.36110998E8 -4.86E7 -0.76 4.84498312E8 -5.23E7 -1.18 -1.372 -0.9768 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B22 compound treatment 4.13573221E8 -7.12E7 -1.11 4.68750585E8 -6.81E7 -1.54 -1.8719 -0.987 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B23 compound treatment 4.10003837E8 -7.47E7 -1.16 4.31432343E8 -1.05E8 -2.38 -2.5076 -0.9458 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 B24 compound treatment 4.07675498E8 -7.71E7 -1.2 4.64113302E8 -7.27E7 -1.64 -2.011 -0.9881 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C01 compound treatment 4.60515648E8 -2.42E7 -0.38 4.85373298E8 -5.15E7 -1.16 -1.0893 -0.8908 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C02 compound treatment 4.51479688E8 -3.33E7 -0.52 4.86250205E8 -5.06E7 -1.14 -1.1748 -0.9359 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C03 compound treatment 4.73327155E8 -1.14E7 -0.18 5.59045328E8 2.22E7 0.5 0.2292 0.4305 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C04 compound treatment 4.5787003E8 -2.69E7 -0.42 5.27643345E8 -9200000.0 -0.21 -0.4429 -0.9478 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C05 compound treatment 4.32496204E8 -5.22E7 -0.81 5.05052801E8 -3.18E7 -0.72 -1.0834 -0.9981 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C06 compound treatment 4.69690548E8 -1.5E7 -0.23 5.16712428E8 -2.01E7 -0.45 -0.4874 -0.9524 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C07 compound treatment 4.61651405E8 -2.31E7 -0.36 5.34987723E8 -1850000.0 -0.04 -0.2839 -0.7842 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C08 compound treatment 4.48295594E8 -3.64E7 -0.57 4.798148E8 -5.7E7 -1.29 -1.3127 -0.9321 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C09 compound treatment 4.67472916E8 -1.73E7 -0.27 4.96719459E8 -4.01E7 -0.91 -0.8313 -0.879 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C10 compound treatment 4.53127938E8 -3.16E7 -0.49 4.98184463E8 -3.87E7 -0.87 -0.9659 -0.9632 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C11 mock treatment 5.16029903E8 3.13E7 0.49 5.38945823E8 2100000.0 0.05 0.3783 0.7724 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C12 mock treatment 4.98034081E8 1.33E7 0.21 5.44743578E8 7900000.0 0.18 0.2727 0.9973 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C13 compound treatment 4.43824988E8 -4.09E7 -0.64 5.1033694E8 -2.65E7 -0.6 -0.8742 -0.9995 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C14 compound treatment 4.62064895E8 -2.27E7 -0.35 5.11833628E8 -2.5E7 -0.57 -0.6494 -0.9744 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C15 mock treatment 4.80031952E8 -4710000.0 -0.07 5.60091572E8 2.33E7 0.53 0.3197 0.6026 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C16 mock treatment 4.75311327E8 -9430000.0 -0.15 5.63214869E8 2.64E7 0.6 0.3176 0.5174 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C17 compound treatment 4.63374091E8 -2.14E7 -0.33 5.20650233E8 -1.62E7 -0.37 -0.494 -0.9989 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C18 compound treatment 4.63728366E8 -2.1E7 -0.33 5.27172878E8 -9670000.0 -0.22 -0.3859 -0.9807 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C19 compound treatment 4.49908378E8 -3.48E7 -0.54 4.96053802E8 -4.08E7 -0.92 -1.0354 -0.9681 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C20 compound treatment 4.63033632E8 -2.17E7 -0.34 5.09789154E8 -2.71E7 -0.61 -0.6714 -0.961 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C21 compound treatment 4.42677708E8 -4.21E7 -0.66 4.91161219E8 -4.57E7 -1.03 -1.1932 -0.9759 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C22 compound treatment 4.36537786E8 -4.82E7 -0.75 4.99712343E8 -3.71E7 -0.84 -1.1242 -0.9985 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C23 compound treatment 4.45046254E8 -3.97E7 -0.62 5.22504855E8 -1.43E7 -0.32 -0.6663 -0.9545 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 C24 compound treatment 4.70553244E8 -1.42E7 -0.22 5.23589864E8 -1.33E7 -0.3 -0.368 -0.9888 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D01 compound treatment 4.50984994E8 -3.38E7 -0.53 5.01089346E8 -3.58E7 -0.81 -0.9431 -0.9783 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D02 compound treatment 4.29561291E8 -5.52E7 -0.86 5.0652518E8 -3.03E7 -0.69 -1.0922 -0.9937 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D03 compound treatment 4.59975355E8 -2.48E7 -0.39 5.39206903E8 2370000.0 0.05 -0.2349 -0.6033 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D04 compound treatment 4.36345936E8 -4.84E7 -0.75 5.14291846E8 -2.25E7 -0.51 -0.8933 -0.9818 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D05 compound treatment 4.685807E8 -1.62E7 -0.25 5.62905349E8 2.61E7 0.59 0.2386 0.3724 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D06 compound treatment 4.33969391E8 -5.08E7 -0.79 5.03487755E8 -3.34E7 -0.75 -1.0922 -0.9997 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D07 compound treatment 4.5465943E8 -3.01E7 -0.47 5.25430432E8 -1.14E7 -0.26 -0.5136 -0.9604 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D08 compound treatment 4.80720038E8 -4020000.0 -0.06 5.5680758E8 2.0E7 0.45 0.2748 0.6033 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D09 compound treatment 4.8201416E8 -2720000.0 -0.04 5.62762736E8 2.59E7 0.59 0.3842 0.6542 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D10 compound treatment 4.59004048E8 -2.57E7 -0.4 5.11906296E8 -2.49E7 -0.56 -0.6819 -0.9861 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D11 mock treatment 4.93471281E8 8730000.0 0.14 5.56244347E8 1.94E7 0.44 0.4063 0.8849 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D12 mock treatment 5.0739817E8 2.27E7 0.35 5.58063926E8 2.12E7 0.48 0.5887 0.9886 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D13 compound treatment 4.57004723E8 -2.77E7 -0.43 5.22518638E8 -1.43E7 -0.32 -0.5343 -0.9899 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D14 compound treatment 4.52989278E8 -3.17E7 -0.49 5.37264845E8 424000.0 0.01 -0.3429 -0.6933 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D15 mock treatment 4.96217472E8 1.15E7 0.18 5.46385506E8 9540000.0 0.22 0.279 0.9957 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D16 mock treatment 4.70686481E8 -1.41E7 -0.22 5.82430459E8 4.56E7 1.03 0.5738 0.5447 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D17 compound treatment 4.44541695E8 -4.02E7 -0.63 5.41108236E8 4270000.0 0.1 -0.3745 -0.5912 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D18 compound treatment 4.27187205E8 -5.76E7 -0.9 4.8884387E8 -4.8E7 -1.08 -1.4009 -0.9955 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D19 compound treatment 4.31556916E8 -5.32E7 -0.83 4.83937257E8 -5.29E7 -1.2 -1.4312 -0.9839 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D20 compound treatment 4.5549557E8 -2.92E7 -0.46 5.46858787E8 1.0E7 0.23 -0.162 -0.3185 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D21 compound treatment 4.50042602E8 -3.47E7 -0.54 5.11208006E8 -2.56E7 -0.58 -0.7918 -0.9994 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D22 compound treatment 4.33974125E8 -5.08E7 -0.79 5.04791464E8 -3.2E7 -0.72 -1.0713 -0.999 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D23 compound treatment 4.67040339E8 -1.77E7 -0.28 5.15767054E8 -2.11E7 -0.48 -0.5317 -0.9662 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 D24 compound treatment 4.53749094E8 -3.1E7 -0.48 5.01598414E8 -3.52E7 -0.8 -0.9045 -0.9712 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E01 mock treatment 4.7093102E8 -1.38E7 -0.22 5.06710102E8 -3.01E7 -0.68 -0.6336 -0.8872 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E02 mock treatment 4.50404381E8 -3.43E7 -0.53 5.13987064E8 -2.29E7 -0.52 -0.7434 -0.9998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E03 compound treatment 4.23158335E8 -6.16E7 -0.96 4.8380745E8 -5.3E7 -1.2 -1.5257 -0.9939 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E04 compound treatment 4.13699489E8 -7.1E7 -1.11 4.81134995E8 -5.57E7 -1.26 -1.6726 -0.9979 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E05 compound treatment 4.20660179E8 -6.41E7 -1.0 4.99881856E8 -3.7E7 -0.84 -1.2964 -0.9961 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E06 compound treatment 4.32548247E8 -5.22E7 -0.81 5.1301722E8 -2.38E7 -0.54 -0.9555 -0.98 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E07 compound treatment 4.2241926E8 -6.23E7 -0.97 5.24015677E8 -1.28E7 -0.29 -0.8913 -0.8799 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E08 compound treatment 4.36032193E8 -4.87E7 -0.76 4.99825559E8 -3.7E7 -0.84 -1.128 -0.9988 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E09 mock treatment 4.67439746E8 -1.73E7 -0.27 5.13853265E8 -2.3E7 -0.52 -0.5579 -0.9533 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E10 mock treatment 4.52269028E8 -3.25E7 -0.51 5.28734213E8 -8110000.0 -0.18 -0.4872 -0.9057 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E11 compound treatment 4.2813326E8 -5.66E7 -0.88 5.15623653E8 -2.12E7 -0.48 -0.9625 -0.959 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E12 compound treatment 4.23498411E8 -6.12E7 -0.95 4.95488459E8 -4.14E7 -0.93 -1.3353 -0.9999 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E13 compound treatment 4.16932477E8 -6.78E7 -1.06 4.61821347E8 -7.5E7 -1.7 -1.9457 -0.9741 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E14 compound treatment 4.32396685E8 -5.23E7 -0.82 5.09468525E8 -2.74E7 -0.62 -1.0139 -0.9907 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E15 compound treatment 4.53556676E8 -3.12E7 -0.49 5.15217313E8 -2.16E7 -0.49 -0.689 -1.0 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E16 compound treatment 4.16867117E8 -6.79E7 -1.06 4.92532495E8 -4.43E7 -1.0 -1.4556 -0.9996 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E17 mock treatment 4.62283137E8 -2.25E7 -0.35 5.14348588E8 -2.25E7 -0.51 -0.6068 -0.9834 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E18 mock treatment 4.80528435E8 -4210000.0 -0.07 5.13299081E8 -2.35E7 -0.53 -0.4226 -0.7883 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E19 compound treatment 4.24691632E8 -6.0E7 -0.94 4.8986817E8 -4.7E7 -1.06 -1.412 -0.998 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E20 compound treatment 4.51582442E8 -3.32E7 -0.52 5.32146277E8 -4690000.0 -0.11 -0.4402 -0.8349 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E21 compound treatment 4.3694873E8 -4.78E7 -0.74 5.14928533E8 -2.19E7 -0.5 -0.8765 -0.9804 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E22 compound treatment 4.40276786E8 -4.45E7 -0.69 5.10622819E8 -2.62E7 -0.59 -0.9087 -0.997 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E23 compound treatment 4.23770375E8 -6.1E7 -0.95 4.90138695E8 -4.67E7 -1.06 -1.4178 -0.9986 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 E24 compound treatment 4.33661505E8 -5.11E7 -0.8 4.74045797E8 -6.28E7 -1.42 -1.5661 -0.9626 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F01 mock treatment 4.6714458E8 -1.76E7 -0.27 5.3809308E8 1250000.0 0.03 -0.1738 -0.6307 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F02 mock treatment 4.74467139E8 -1.03E7 -0.16 5.71306833E8 3.45E7 0.78 0.4377 0.5504 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F03 compound treatment 4.56685252E8 -2.81E7 -0.44 5.04524997E8 -3.23E7 -0.73 -0.8254 -0.9698 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F04 compound treatment 4.55235255E8 -2.95E7 -0.46 5.30963336E8 -5880000.0 -0.13 -0.4189 -0.8757 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F05 compound treatment 4.59942351E8 -2.48E7 -0.39 4.9226419E8 -4.46E7 -1.01 -0.9855 -0.9134 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F06 compound treatment 4.55195005E8 -2.95E7 -0.46 5.16534796E8 -2.03E7 -0.46 -0.6499 -1.0 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F07 compound treatment 4.57839144E8 -2.69E7 -0.42 5.26367407E8 -1.05E7 -0.24 -0.4636 -0.9635 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F08 compound treatment 4.73311712E8 -1.14E7 -0.18 4.98050933E8 -3.88E7 -0.88 -0.7457 -0.8337 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F09 mock treatment 4.87617712E8 2880000.0 0.04 5.46831066E8 9990000.0 0.23 0.1914 0.8313 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F10 mock treatment 4.97314514E8 1.26E7 0.2 5.43107098E8 6270000.0 0.14 0.2387 0.9873 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F11 compound treatment 4.6484716E8 -1.99E7 -0.31 5.08972381E8 -2.79E7 -0.63 -0.6644 -0.9466 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F12 compound treatment 4.50164515E8 -3.46E7 -0.54 5.11543393E8 -2.53E7 -0.57 -0.7851 -0.9996 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F13 compound treatment 4.38234352E8 -4.65E7 -0.72 5.11291633E8 -2.55E7 -0.58 -0.9205 -0.9937 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F14 compound treatment 4.30102214E8 -5.46E7 -0.85 4.66746036E8 -7.01E7 -1.58 -1.7219 -0.9575 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F15 compound treatment 4.46094015E8 -3.86E7 -0.6 5.12079959E8 -2.48E7 -0.56 -0.8213 -0.9993 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F16 compound treatment 4.47719279E8 -3.7E7 -0.58 5.03785249E8 -3.31E7 -0.75 -0.936 -0.9918 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F17 mock treatment 4.77140394E8 -7600000.0 -0.12 5.36268098E8 -573000.0 -0.01 -0.0928 -0.7798 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F18 mock treatment 4.99713187E8 1.5E7 0.23 5.45900782E8 9060000.0 0.2 0.3097 0.9979 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F19 compound treatment 4.40559E8 -4.42E7 -0.69 4.95053614E8 -4.18E7 -0.94 -1.1544 -0.9879 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F20 compound treatment 4.59668637E8 -2.51E7 -0.39 5.19109214E8 -1.77E7 -0.4 -0.5595 -0.9999 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F21 compound treatment 4.45045154E8 -3.97E7 -0.62 5.12836782E8 -2.4E7 -0.54 -0.8208 -0.9979 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F22 compound treatment 4.51917716E8 -3.28E7 -0.51 4.99777981E8 -3.71E7 -0.84 -0.9538 -0.9719 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F23 compound treatment 4.43361253E8 -4.14E7 -0.64 4.93535965E8 -4.33E7 -0.98 -1.1478 -0.9795 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 F24 compound treatment 4.58336581E8 -2.64E7 -0.41 4.9208432E8 -4.48E7 -1.01 -1.006 -0.9214 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G01 compound treatment 4.40069787E8 -4.47E7 -0.7 4.99804287E8 -3.7E7 -0.84 -1.0838 -0.9958 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G02 compound treatment 4.7791422E8 -6820000.0 -0.11 5.51482573E8 1.46E7 0.33 0.1588 0.457 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G03 mock treatment 4.98652721E8 1.39E7 0.22 5.71800615E8 3.5E7 0.79 0.7119 0.869 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G04 mock treatment 4.75763019E8 -8980000.0 -0.14 5.86401441E8 4.96E7 1.12 0.6932 0.6141 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G05 compound treatment 4.65681084E8 -1.91E7 -0.3 5.34922504E8 -1920000.0 -0.04 -0.2406 -0.8019 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G06 compound treatment 4.66089101E8 -1.86E7 -0.29 5.75425966E8 3.86E7 0.87 0.4112 0.4474 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G07 compound treatment 4.28466811E8 -5.63E7 -0.88 5.00263629E8 -3.66E7 -0.83 -1.2043 -0.9996 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G08 compound treatment 4.64441031E8 -2.03E7 -0.32 5.36420032E8 -421000.0 -0.01 -0.2303 -0.7281 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G09 compound treatment 5.04819839E8 2.01E7 0.31 5.61988119E8 2.51E7 0.57 0.623 0.9604 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G10 compound treatment 4.73303324E8 -1.14E7 -0.18 5.15519462E8 -2.13E7 -0.48 -0.4667 -0.9084 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G11 compound treatment 4.68378126E8 -1.64E7 -0.25 5.51695402E8 1.49E7 0.34 0.0572 0.1357 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G12 compound treatment 4.61618457E8 -2.31E7 -0.36 5.40385511E8 3540000.0 0.08 -0.198 -0.5367 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G13 compound treatment 4.72197856E8 -1.25E7 -0.2 5.30126277E8 -6710000.0 -0.15 -0.2454 -0.9922 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G14 compound treatment 4.9440698E8 9670000.0 0.15 5.50727859E8 1.39E7 0.31 0.3284 0.9434 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G15 compound treatment 4.69796693E8 -1.49E7 -0.23 5.44800913E8 7960000.0 0.18 -0.0374 -0.127 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G16 compound treatment 4.52347905E8 -3.24E7 -0.5 4.85783894E8 -5.11E7 -1.15 -1.1727 -0.9312 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G17 compound treatment 4.6438786E8 -2.04E7 -0.32 5.34016865E8 -2820000.0 -0.06 -0.2693 -0.8328 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G18 compound treatment 4.84364172E8 -374000.0 -0.01 5.39870704E8 3030000.0 0.07 0.0443 0.6446 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G19 mock treatment 5.03524813E8 1.88E7 0.29 5.44562994E8 7720000.0 0.17 0.3303 0.9695 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G20 mock treatment 5.20982744E8 3.62E7 0.56 5.53421186E8 1.66E7 0.37 0.6642 0.9802 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G21 compound treatment 4.60113408E8 -2.46E7 -0.38 5.07704001E8 -2.91E7 -0.66 -0.7368 -0.9669 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G22 compound treatment 4.73905289E8 -1.08E7 -0.17 5.48277934E8 1.14E7 0.26 0.0635 0.2056 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G23 compound treatment 4.68493435E8 -1.62E7 -0.25 5.22020393E8 -1.48E7 -0.33 -0.4158 -0.9904 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 G24 compound treatment 4.57104595E8 -2.76E7 -0.43 4.94009555E8 -4.28E7 -0.97 -0.9888 -0.9334 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H01 compound treatment 4.80426974E8 -4310000.0 -0.07 5.32685869E8 -4160000.0 -0.09 -0.1139 -0.9865 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H02 compound treatment 4.76692841E8 -8050000.0 -0.13 5.47208846E8 1.04E7 0.23 0.0771 0.2901 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H03 mock treatment 5.17993689E8 3.33E7 0.52 5.78334755E8 4.15E7 0.94 1.0294 0.9609 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H04 mock treatment 5.21571581E8 3.68E7 0.57 5.68084956E8 3.12E7 0.71 0.905 0.9947 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H05 compound treatment 4.69474392E8 -1.53E7 -0.24 5.32549693E8 -4290000.0 -0.1 -0.2367 -0.9218 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H06 compound treatment 4.79263522E8 -5470000.0 -0.09 5.09080487E8 -2.78E7 -0.63 -0.5039 -0.7959 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H07 compound treatment 4.77397073E8 -7340000.0 -0.11 5.23831374E8 -1.3E7 -0.29 -0.2888 -0.9153 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H08 compound treatment 5.10608252E8 2.59E7 0.4 5.36024241E8 -817000.0 -0.02 0.2719 0.674 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H09 compound treatment 5.08739369E8 2.4E7 0.37 5.47693736E8 1.09E7 0.25 0.4378 0.9791 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H10 compound treatment 5.02379755E8 1.76E7 0.27 5.34584287E8 -2260000.0 -0.05 0.1582 0.5662 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H11 compound treatment 5.04601679E8 1.99E7 0.31 5.4118253E8 4340000.0 0.1 0.2882 0.8878 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H12 compound treatment 5.07634203E8 2.29E7 0.36 5.487237E8 1.19E7 0.27 0.4421 0.9902 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H13 compound treatment 4.70244728E8 -1.45E7 -0.23 5.24497652E8 -1.23E7 -0.28 -0.3569 -0.9945 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H14 compound treatment 4.84723738E8 -14500.0 0.0 5.28271394E8 -8570000.0 -0.19 -0.1371 -0.7079 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H15 compound treatment 4.83710498E8 -1030000.0 -0.02 5.39689354E8 2850000.0 0.06 0.0342 0.5156 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H16 compound treatment 5.03871513E8 1.91E7 0.3 5.41510666E8 4670000.0 0.11 0.2854 0.9026 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H17 compound treatment 4.80214999E8 -4520000.0 -0.07 5.11668362E8 -2.52E7 -0.57 -0.4521 -0.7887 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H18 compound treatment 4.92336189E8 7600000.0 0.12 5.38773686E8 1930000.0 0.04 0.1146 0.9082 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H19 mock treatment 5.16856336E8 3.21E7 0.5 5.62320332E8 2.55E7 0.58 0.7609 0.9975 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H20 mock treatment 5.15519699E8 3.08E7 0.48 5.64531668E8 2.77E7 0.63 0.7815 0.9913 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H21 compound treatment 4.79669046E8 -5070000.0 -0.08 5.28081574E8 -8760000.0 -0.2 -0.1958 -0.9188 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H22 compound treatment 4.75127654E8 -9610000.0 -0.15 5.4756597E8 1.07E7 0.24 0.0655 0.2301 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H23 compound treatment 4.76782687E8 -7960000.0 -0.12 5.3759837E8 757000.0 0.02 -0.0755 -0.6037 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 H24 compound treatment 4.94582604E8 9840000.0 0.15 5.52165733E8 1.53E7 0.35 0.3533 0.9328 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I01 compound treatment 4.30900629E8 -5.38E7 -0.84 5.13213863E8 -2.36E7 -0.53 -0.9705 -0.9762 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I02 compound treatment 4.07901718E8 -7.68E7 -1.2 4.58390699E8 -7.85E7 -1.77 -2.1 -0.9817 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I03 compound treatment 3.64500466E8 -1.2E8 -1.87 4.22375474E8 -1.14E8 -2.59 -3.1535 -0.9874 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I04 compound treatment 4.56209219E8 -2.85E7 -0.44 4.87710525E8 -4.91E7 -1.11 -1.0994 -0.9192 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I05 mock treatment 4.61297571E8 -2.34E7 -0.37 5.10437011E8 -2.64E7 -0.6 -0.6801 -0.9722 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I06 mock treatment 4.61479367E8 -2.33E7 -0.36 5.13059997E8 -2.38E7 -0.54 -0.6362 -0.9816 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I07 compound treatment 4.06239998E8 -7.85E7 -1.22 4.82015431E8 -5.48E7 -1.24 -1.7407 -1.0 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I08 compound treatment 4.07515179E8 -7.72E7 -1.2 4.91248954E8 -4.56E7 -1.03 -1.5791 -0.997 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I09 compound treatment 4.34043687E8 -5.07E7 -0.79 5.33295045E8 -3550000.0 -0.08 -0.615 -0.7749 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I10 compound treatment 4.53543977E8 -3.12E7 -0.49 4.97081631E8 -3.98E7 -0.9 -0.979 -0.9583 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I11 compound treatment 4.59221687E8 -2.55E7 -0.4 5.0975845E8 -2.71E7 -0.61 -0.7138 -0.9781 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I12 compound treatment 4.02205609E8 -8.25E7 -1.29 4.6131082E8 -7.55E7 -1.71 -2.116 -0.9902 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I13 compound treatment 3.98438746E8 -8.63E7 -1.34 4.38909063E8 -9.79E7 -2.21 -2.5155 -0.9714 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I14 compound treatment 4.41158106E8 -4.36E7 -0.68 4.86976123E8 -4.99E7 -1.13 -1.2769 -0.9706 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I15 compound treatment 4.49400438E8 -3.53E7 -0.55 4.88815329E8 -4.8E7 -1.09 -1.1567 -0.9505 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I16 compound treatment 4.15906973E8 -6.88E7 -1.07 4.36971645E8 -9.99E7 -2.26 -2.3541 -0.9421 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I17 compound treatment 3.75394139E8 -1.09E8 -1.7 4.3909897E8 -9.77E7 -2.21 -2.7663 -0.9917 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I18 compound treatment 4.36043567E8 -4.87E7 -0.76 4.92922503E8 -4.39E7 -0.99 -1.2382 -0.9912 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I19 compound treatment 4.31887142E8 -5.29E7 -0.82 5.02164835E8 -3.47E7 -0.78 -1.1362 -0.9997 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I20 compound treatment 4.07352417E8 -7.74E7 -1.21 4.46261179E8 -9.06E7 -2.05 -2.2998 -0.9681 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I21 mock treatment 4.64218973E8 -2.05E7 -0.32 5.06238019E8 -3.06E7 -0.69 -0.7151 -0.9385 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I22 mock treatment 4.68235451E8 -1.65E7 -0.26 5.05281783E8 -3.16E7 -0.71 -0.6861 -0.905 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I23 compound treatment 3.58435456E8 -1.26E8 -1.97 4.07097078E8 -1.3E8 -2.93 -3.4645 -0.9812 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 I24 compound treatment 3.97733431E8 -8.7E7 -1.36 4.30799289E8 -1.06E8 -2.4 -2.6529 -0.9636 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J01 compound treatment 4.5038955E8 -3.43E7 -0.54 4.77827603E8 -5.9E7 -1.33 -1.3214 -0.9195 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J02 compound treatment 4.15620458E8 -6.91E7 -1.08 5.08241415E8 -2.86E7 -0.65 -1.2183 -0.9702 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J03 compound treatment 4.61101071E8 -2.36E7 -0.37 5.42099761E8 5260000.0 0.12 -0.1763 -0.4557 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J04 compound treatment 4.64594545E8 -2.01E7 -0.31 5.32246787E8 -4590000.0 -0.1 -0.2953 -0.8935 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J05 mock treatment 4.77205251E8 -7530000.0 -0.12 5.19210418E8 -1.76E7 -0.4 -0.3647 -0.8781 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J06 mock treatment 4.85673689E8 935000.0 0.01 5.27373795E8 -9470000.0 -0.21 -0.141 -0.6574 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J07 compound treatment 4.33918965E8 -5.08E7 -0.79 4.86869498E8 -5.0E7 -1.13 -1.3583 -0.9849 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J08 compound treatment 4.60833592E8 -2.39E7 -0.37 4.80707903E8 -5.61E7 -1.27 -1.1603 -0.8776 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J09 compound treatment 4.41124462E8 -4.36E7 -0.68 4.8952187E8 -4.73E7 -1.07 -1.2365 -0.976 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J10 compound treatment 4.79077108E8 -5660000.0 -0.09 5.45375092E8 8530000.0 0.19 0.074 0.3491 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J11 compound treatment 4.54468115E8 -3.03E7 -0.47 4.92178165E8 -4.47E7 -1.01 -1.0471 -0.9399 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J12 compound treatment 3.81830342E8 -1.03E8 -1.6 4.28901675E8 -1.08E8 -2.44 -2.8584 -0.9793 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J13 compound treatment 4.30508277E8 -5.42E7 -0.84 4.97186433E8 -3.97E7 -0.9 -1.231 -0.9996 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J14 compound treatment 4.50477352E8 -3.43E7 -0.53 5.15485778E8 -2.14E7 -0.48 -0.7186 -0.9987 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J15 compound treatment 4.30085818E8 -5.47E7 -0.85 4.89826663E8 -4.7E7 -1.06 -1.3533 -0.994 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J16 compound treatment 4.37067701E8 -4.77E7 -0.74 4.95993778E8 -4.08E7 -0.92 -1.1778 -0.9942 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J17 compound treatment 4.7092061E8 -1.38E7 -0.22 4.92528037E8 -4.43E7 -1.0 -0.8603 -0.8399 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J18 compound treatment 4.10117244E8 -7.46E7 -1.16 4.51340595E8 -8.55E7 -1.93 -2.1882 -0.9704 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J19 compound treatment 4.21140778E8 -6.36E7 -0.99 4.73646031E8 -6.32E7 -1.43 -1.7104 -0.984 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J20 compound treatment 4.83227572E8 -1510000.0 -0.02 5.23509499E8 -1.33E7 -0.3 -0.2297 -0.76 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J21 mock treatment 4.86642842E8 1900000.0 0.03 5.32790784E8 -4050000.0 -0.09 -0.0437 -0.4546 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J22 mock treatment 4.78804434E8 -5930000.0 -0.09 5.11621796E8 -2.52E7 -0.57 -0.4684 -0.8112 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J23 compound treatment 4.13199215E8 -7.15E7 -1.11 4.66848539E8 -7.0E7 -1.58 -1.9064 -0.9853 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 J24 compound treatment 4.16873881E8 -6.79E7 -1.06 4.9714494E8 -3.97E7 -0.9 -1.3818 -0.9967 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K01 compound treatment 4.2136177E8 -6.34E7 -0.99 4.6633074E8 -7.05E7 -1.59 -1.8248 -0.9735 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K02 compound treatment 4.42780929E8 -4.2E7 -0.65 4.99471937E8 -3.74E7 -0.84 -1.0593 -0.992 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K03 compound treatment 4.45415939E8 -3.93E7 -0.61 5.21390228E8 -1.55E7 -0.35 -0.68 -0.9645 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K04 compound treatment 3.96216215E8 -8.85E7 -1.38 4.4549351E8 -9.13E7 -2.06 -2.4348 -0.9807 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K05 compound treatment 4.38765466E8 -4.6E7 -0.72 5.04694004E8 -3.21E7 -0.73 -1.0201 -1.0 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K06 compound treatment 4.4778967E8 -3.69E7 -0.58 4.99606674E8 -3.72E7 -0.84 -1.002 -0.9828 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K07 mock treatment 5.01759475E8 1.7E7 0.27 5.28595719E8 -8250000.0 -0.19 0.0557 0.1719 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K08 mock treatment 4.72379741E8 -1.24E7 -0.19 5.27566435E8 -9270000.0 -0.21 -0.2843 -0.9991 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K09 compound treatment 3.99606667E8 -8.51E7 -1.33 4.65824147E8 -7.1E7 -1.6 -2.0725 -0.9955 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K10 compound treatment 4.40910857E8 -4.38E7 -0.68 5.06463178E8 -3.04E7 -0.69 -0.9682 -1.0 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K11 compound treatment 4.15469221E8 -6.93E7 -1.08 4.60558368E8 -7.63E7 -1.72 -1.982 -0.9745 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K12 compound treatment 4.48864632E8 -3.59E7 -0.56 5.08423913E8 -2.84E7 -0.64 -0.8492 -0.9976 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K13 compound treatment 3.92883967E8 -9.19E7 -1.43 4.40767043E8 -9.61E7 -2.17 -2.547 -0.9795 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K14 compound treatment 4.24662053E8 -6.01E7 -0.94 4.49508526E8 -8.73E7 -1.97 -2.0573 -0.9419 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K15 mock treatment 4.66966041E8 -1.78E7 -0.28 5.04301977E8 -3.25E7 -0.74 -0.7157 -0.9109 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K16 mock treatment 4.76190138E8 -8550000.0 -0.13 4.91313256E8 -4.55E7 -1.03 -0.8217 -0.792 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K17 compound treatment 4.41926939E8 -4.28E7 -0.67 4.62323815E8 -7.45E7 -1.68 -1.6624 -0.9178 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K18 compound treatment 4.49779097E8 -3.5E7 -0.54 4.70984777E8 -6.59E7 -1.49 -1.4375 -0.907 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K19 compound treatment 4.08729187E8 -7.6E7 -1.18 4.52941199E8 -8.39E7 -1.9 -2.1779 -0.9743 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K20 compound treatment 4.58593967E8 -2.61E7 -0.41 5.16433076E8 -2.04E7 -0.46 -0.6141 -0.9981 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K21 compound treatment 4.44427936E8 -4.03E7 -0.63 4.8709617E8 -4.97E7 -1.12 -1.2389 -0.9621 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K22 compound treatment 4.31824112E8 -5.29E7 -0.82 4.91675546E8 -4.52E7 -1.02 -1.3046 -0.9944 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K23 mock treatment 4.58417599E8 -2.63E7 -0.41 5.13618072E8 -2.32E7 -0.52 -0.661 -0.9925 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 K24 mock treatment 4.7858963E8 -6150000.0 -0.1 4.93505478E8 -4.33E7 -0.98 -0.7602 -0.7726 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L01 compound treatment 4.40719882E8 -4.4E7 -0.69 5.32667415E8 -4170000.0 -0.09 -0.5515 -0.7969 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L02 compound treatment 4.12787186E8 -7.2E7 -1.12 4.79419739E8 -5.74E7 -1.3 -1.7101 -0.9973 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L03 compound treatment 4.74241371E8 -1.05E7 -0.16 5.19161621E8 -1.77E7 -0.4 -0.3981 -0.9222 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L04 compound treatment 4.49853945E8 -3.49E7 -0.54 5.11522364E8 -2.53E7 -0.57 -0.7888 -0.9997 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L05 compound treatment 4.68243935E8 -1.65E7 -0.26 5.36509265E8 -332000.0 -0.01 -0.187 -0.7274 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L06 compound treatment 4.47424194E8 -3.73E7 -0.58 5.15892701E8 -2.09E7 -0.47 -0.7457 -0.9948 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L07 mock treatment 4.94198938E8 9460000.0 0.15 5.44442759E8 7600000.0 0.17 0.2257 0.9971 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L08 mock treatment 5.17107367E8 3.24E7 0.5 5.44901387E8 8060000.0 0.18 0.4853 0.9053 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L09 compound treatment 4.63913714E8 -2.08E7 -0.32 4.81051982E8 -5.58E7 -1.26 -1.1209 -0.861 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L10 compound treatment 4.8881173E8 4070000.0 0.06 5.23534389E8 -1.33E7 -0.3 -0.1678 -0.5459 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L11 compound treatment 4.88688976E8 3950000.0 0.06 4.80395857E8 -5.64E7 -1.28 -0.8585 -0.6722 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L12 compound treatment 4.59967408E8 -2.48E7 -0.39 5.0196714E8 -3.49E7 -0.79 -0.8301 -0.946 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L13 compound treatment 4.36116568E8 -4.86E7 -0.76 4.98500757E8 -3.83E7 -0.87 -1.1482 -0.9977 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L14 compound treatment 4.73122389E8 -1.16E7 -0.18 5.19750036E8 -1.71E7 -0.39 -0.4011 -0.9403 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L15 mock treatment 4.91390264E8 6650000.0 0.1 5.47516648E8 1.07E7 0.24 0.2439 0.9288 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L16 mock treatment 5.14911392E8 3.02E7 0.47 5.4209513E8 5250000.0 0.12 0.4163 0.8588 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L17 compound treatment 4.67805732E8 -1.69E7 -0.26 5.05536958E8 -3.13E7 -0.71 -0.6868 -0.9096 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L18 compound treatment 4.85576272E8 838000.0 0.01 5.40228983E8 3390000.0 0.08 0.0634 0.8159 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L19 compound treatment 4.46714125E8 -3.8E7 -0.59 4.86392886E8 -5.04E7 -1.14 -1.225 -0.9535 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L20 compound treatment 4.92761886E8 8020000.0 0.12 5.16143969E8 -2.07E7 -0.47 -0.2424 -0.5006 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L21 compound treatment 4.29265112E8 -5.55E7 -0.86 4.53515938E8 -8.33E7 -1.88 -1.9426 -0.9376 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L22 compound treatment 4.75484208E8 -9250000.0 -0.14 5.25197301E8 -1.16E7 -0.26 -0.288 -0.9599 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L23 mock treatment 4.93833369E8 9100000.0 0.14 5.26487698E8 -1.04E7 -0.23 -0.0653 -0.2387 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 L24 mock treatment 4.73383145E8 -1.14E7 -0.18 5.34685514E8 -2160000.0 -0.05 -0.1595 -0.8695 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M01 compound treatment 4.68646764E8 -1.61E7 -0.25 5.08100821E8 -2.87E7 -0.65 -0.6365 -0.9143 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M02 compound treatment 4.39865812E8 -4.49E7 -0.7 5.13226339E8 -2.36E7 -0.53 -0.8716 -0.9911 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M03 compound treatment 4.45324762E8 -3.94E7 -0.61 4.91429226E8 -4.54E7 -1.03 -1.1598 -0.9698 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M04 compound treatment 4.46368384E8 -3.84E7 -0.6 5.16159964E8 -2.07E7 -0.47 -0.7531 -0.9926 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M05 compound treatment 4.43038507E8 -4.17E7 -0.65 5.12650034E8 -2.42E7 -0.55 -0.8459 -0.9963 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M06 compound treatment 4.57940777E8 -2.68E7 -0.42 4.8866992E8 -4.82E7 -1.09 -1.0649 -0.9134 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M07 compound treatment 4.51614361E8 -3.31E7 -0.52 5.35139592E8 -1700000.0 -0.04 -0.392 -0.7577 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M08 compound treatment 4.45064989E8 -3.97E7 -0.62 5.03698982E8 -3.31E7 -0.75 -0.9666 -0.9954 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M09 mock treatment 4.92189226E8 7450000.0 0.12 5.77333199E8 4.05E7 0.92 0.7292 0.7905 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M10 mock treatment 4.80088505E8 -4650000.0 -0.07 5.13452704E8 -2.34E7 -0.53 -0.425 -0.7965 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M11 compound treatment 4.28579684E8 -5.62E7 -0.87 4.80015187E8 -5.68E7 -1.28 -1.5266 -0.9825 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M12 compound treatment 4.538681E8 -3.09E7 -0.48 5.0266682E8 -3.42E7 -0.77 -0.8861 -0.974 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M13 mock treatment 4.62428898E8 -2.23E7 -0.35 5.24407085E8 -1.24E7 -0.28 -0.4444 -0.9945 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M14 mock treatment 4.67615551E8 -1.71E7 -0.27 5.4198456E8 5140000.0 0.12 -0.1064 -0.3657 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M15 compound treatment 4.41057635E8 -4.37E7 -0.68 4.67932044E8 -6.89E7 -1.56 -1.5823 -0.9311 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M16 compound treatment 3.95367476E8 -8.94E7 -1.39 4.8992522E8 -4.69E7 -1.06 -1.7341 -0.991 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M17 compound treatment 4.37987964E8 -4.68E7 -0.73 4.789561E8 -5.79E7 -1.31 -1.4399 -0.9617 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M18 compound treatment 4.42580246E8 -4.22E7 -0.66 4.82987315E8 -5.39E7 -1.22 -1.3249 -0.9581 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M19 compound treatment 4.35340327E8 -4.94E7 -0.77 5.0809429E8 -2.87E7 -0.65 -1.0035 -0.9965 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M20 compound treatment 4.22235336E8 -6.25E7 -0.97 4.59424739E8 -7.74E7 -1.75 -1.9256 -0.9617 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M21 compound treatment 4.36641938E8 -4.81E7 -0.75 4.85075726E8 -5.18E7 -1.17 -1.357 -0.9768 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M22 compound treatment 4.35949807E8 -4.88E7 -0.76 5.1776749E8 -1.91E7 -0.43 -0.8422 -0.9639 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M23 compound treatment 4.34154235E8 -5.06E7 -0.79 4.86166591E8 -5.07E7 -1.15 -1.3669 -0.9833 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 M24 compound treatment 4.11600203E8 -7.31E7 -1.14 4.77795825E8 -5.9E7 -1.33 -1.7491 -0.9969 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N01 compound treatment 4.51026883E8 -3.37E7 -0.53 5.4712899E8 1.03E7 0.23 -0.2069 -0.3603 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N02 compound treatment 4.99598114E8 1.49E7 0.23 5.37518076E8 677000.0 0.02 0.1745 0.7522 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N03 compound treatment 4.30915843E8 -5.38E7 -0.84 4.80637778E8 -5.62E7 -1.27 -1.491 -0.9797 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N04 compound treatment 4.79149005E8 -5590000.0 -0.09 5.49519256E8 1.27E7 0.29 0.141 0.471 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N05 compound treatment 4.27179081E8 -5.76E7 -0.9 4.7558092E8 -6.13E7 -1.38 -1.6129 -0.9779 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N06 compound treatment 4.5791139E8 -2.68E7 -0.42 5.18597316E8 -1.82E7 -0.41 -0.587 -1.0 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N07 compound treatment 4.65445881E8 -1.93E7 -0.3 5.42200321E8 5360000.0 0.12 -0.1268 -0.3915 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N08 compound treatment 5.01122562E8 1.64E7 0.26 5.162459E8 -2.06E7 -0.47 -0.1487 -0.2801 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N09 mock treatment 5.12879522E8 2.81E7 0.44 5.82217936E8 4.54E7 1.03 1.0351 0.9281 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N10 mock treatment 4.90880356E8 6140000.0 0.1 5.62667179E8 2.58E7 0.58 0.4804 0.8122 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N11 compound treatment 4.35789447E8 -4.89E7 -0.76 5.51029692E8 1.42E7 0.32 -0.3124 -0.3777 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N12 compound treatment 4.57120713E8 -2.76E7 -0.43 5.29095139E8 -7750000.0 -0.18 -0.428 -0.9215 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N13 mock treatment 4.96917885E8 1.22E7 0.19 5.62831671E8 2.6E7 0.59 0.5495 0.8902 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N14 mock treatment 4.74432517E8 -1.03E7 -0.16 5.38734608E8 1890000.0 0.04 -0.0832 -0.5011 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N15 compound treatment 4.60614341E8 -2.41E7 -0.38 5.40137448E8 3300000.0 0.07 -0.213 -0.5561 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N16 compound treatment 4.73011926E8 -1.17E7 -0.18 5.50157679E8 1.33E7 0.3 0.0837 0.2376 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N17 compound treatment 4.49623539E8 -3.51E7 -0.55 5.25788345E8 -1.11E7 -0.25 -0.5634 -0.937 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N18 compound treatment 4.59204116E8 -2.55E7 -0.4 5.12262773E8 -2.46E7 -0.56 -0.674 -0.9866 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N19 compound treatment 4.27285075E8 -5.75E7 -0.89 4.95524904E8 -4.13E7 -0.93 -1.293 -0.9998 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N20 compound treatment 4.54443523E8 -3.03E7 -0.47 5.3357605E8 -3260000.0 -0.07 -0.3858 -0.8079 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N21 compound treatment 4.25934696E8 -5.88E7 -0.92 4.99206704E8 -3.76E7 -0.85 -1.2491 -0.9993 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N22 compound treatment 4.40474047E8 -4.43E7 -0.69 5.14452782E8 -2.24E7 -0.51 -0.8453 -0.9884 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N23 compound treatment 4.47892929E8 -3.68E7 -0.57 5.27471399E8 -9370000.0 -0.21 -0.5555 -0.9082 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 N24 compound treatment 4.19792898E8 -6.49E7 -1.01 5.00198334E8 -3.66E7 -0.83 -1.3009 -0.9951 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O01 compound treatment 4.79306372E8 -5430000.0 -0.08 5.04244472E8 -3.26E7 -0.74 -0.5807 -0.7832 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O02 compound treatment 4.47757356E8 -3.7E7 -0.58 5.33917546E8 -2920000.0 -0.07 -0.454 -0.7831 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O03 compound treatment 4.69275525E8 -1.55E7 -0.24 5.39316979E8 2480000.0 0.06 -0.1307 -0.5287 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O04 compound treatment 4.73184098E8 -1.16E7 -0.18 5.14032798E8 -2.28E7 -0.52 -0.4917 -0.9007 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O05 compound treatment 4.54558049E8 -3.02E7 -0.47 5.12219561E8 -2.46E7 -0.56 -0.7259 -0.9965 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O06 compound treatment 4.64334492E8 -2.04E7 -0.32 5.32429341E8 -4410000.0 -0.1 -0.2952 -0.8863 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O07 compound treatment 4.4973269E8 -3.5E7 -0.55 5.23007591E8 -1.38E7 -0.31 -0.6066 -0.9652 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O08 compound treatment 4.82282341E8 -2460000.0 -0.04 5.26347695E8 -1.05E7 -0.24 -0.1947 -0.8107 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O09 compound treatment 4.68868671E8 -1.59E7 -0.25 5.04245432E8 -3.26E7 -0.74 -0.6957 -0.8953 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O10 compound treatment 4.76709766E8 -8030000.0 -0.13 4.95331379E8 -4.15E7 -0.94 -0.7518 -0.7943 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O11 mock treatment 5.00079416E8 1.53E7 0.24 5.62402332E8 2.56E7 0.58 0.5775 0.9237 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O12 mock treatment 4.93439703E8 8700000.0 0.14 5.33930777E8 -2910000.0 -0.07 0.0493 0.3275 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O13 compound treatment 4.73035791E8 -1.17E7 -0.18 5.26637075E8 -1.02E7 -0.23 -0.292 -0.9932 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O14 compound treatment 4.55445964E8 -2.93E7 -0.46 5.24635217E8 -1.22E7 -0.28 -0.5177 -0.971 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O15 compound treatment 4.72473679E8 -1.23E7 -0.19 4.968771E8 -4.0E7 -0.9 -0.7737 -0.8381 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O16 compound treatment 4.52665798E8 -3.21E7 -0.5 5.18397665E8 -1.84E7 -0.42 -0.648 -0.9959 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O17 compound treatment 4.40042078E8 -4.47E7 -0.7 5.13167101E8 -2.37E7 -0.54 -0.8706 -0.9915 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O18 compound treatment 4.51899071E8 -3.28E7 -0.51 4.9534984E8 -4.15E7 -0.94 -1.0247 -0.9594 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O19 compound treatment 4.66811323E8 -1.79E7 -0.28 5.15555173E8 -2.13E7 -0.48 -0.5376 -0.9665 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O20 compound treatment 4.68438191E8 -1.63E7 -0.25 5.21397715E8 -1.54E7 -0.35 -0.4263 -0.9878 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O21 compound treatment 4.48643491E8 -3.61E7 -0.56 5.07056908E8 -2.98E7 -0.67 -0.8735 -0.996 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O22 compound treatment 4.26247572E8 -5.85E7 -0.91 4.9020164E8 -4.66E7 -1.05 -1.3895 -0.9974 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O23 compound treatment 4.49701595E8 -3.5E7 -0.55 5.04764771E8 -3.21E7 -0.72 -0.8985 -0.9902 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 O24 compound treatment 4.41817715E8 -4.29E7 -0.67 5.1018517E8 -2.67E7 -0.6 -0.8987 -0.9987 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P01 compound treatment 4.6094364E8 -2.38E7 -0.37 5.23501191E8 -1.33E7 -0.3 -0.4752 -0.9947 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P02 compound treatment 4.7422347E8 -1.05E7 -0.16 5.5151844E8 1.47E7 0.33 0.1187 0.321 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P03 compound treatment 4.77391036E8 -7350000.0 -0.11 5.69803683E8 3.3E7 0.74 0.4458 0.5915 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P04 compound treatment 4.80617435E8 -4120000.0 -0.06 5.4401314E8 7170000.0 0.16 0.0692 0.3971 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P05 compound treatment 4.96620538E8 1.19E7 0.19 5.68727192E8 3.19E7 0.72 0.6404 0.8608 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P06 compound treatment 4.71165128E8 -1.36E7 -0.21 5.65175794E8 2.83E7 0.64 0.3033 0.4498 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P07 compound treatment 4.43106559E8 -4.16E7 -0.65 5.19507176E8 -1.73E7 -0.39 -0.7355 -0.9709 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P08 compound treatment 4.493477E8 -3.54E7 -0.55 5.21353623E8 -1.55E7 -0.35 -0.6373 -0.976 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P09 compound treatment 4.53073811E8 -3.17E7 -0.49 5.35349817E8 -1490000.0 -0.03 -0.3726 -0.7537 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P10 compound treatment 4.70111407E8 -1.46E7 -0.23 5.17571022E8 -1.93E7 -0.44 -0.469 -0.9543 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P11 mock treatment 4.91404839E8 6670000.0 0.1 5.43812338E8 6970000.0 0.16 0.1848 0.9795 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P12 mock treatment 4.99086627E8 1.43E7 0.22 5.41342849E8 4500000.0 0.1 0.23 0.9365 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P13 compound treatment 4.72041966E8 -1.27E7 -0.2 5.38388281E8 1550000.0 0.03 -0.1151 -0.5732 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P14 compound treatment 4.83905958E8 -832000.0 -0.01 5.3243896E8 -4400000.0 -0.1 -0.0795 -0.7925 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P15 compound treatment 4.67065878E8 -1.77E7 -0.28 5.26613007E8 -1.02E7 -0.23 -0.3581 -0.9962 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P16 compound treatment 4.44146884E8 -4.06E7 -0.63 5.2944961E8 -7390000.0 -0.17 -0.5652 -0.8643 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P17 compound treatment 4.73798915E8 -1.09E7 -0.17 5.37221599E8 381000.0 0.01 -0.1144 -0.6706 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P18 compound treatment 4.80663504E8 -4070000.0 -0.06 5.29047676E8 -7790000.0 -0.18 -0.1694 -0.9049 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P19 compound treatment 4.69946825E8 -1.48E7 -0.23 5.21010738E8 -1.58E7 -0.36 -0.4159 -0.9773 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P20 compound treatment 4.85477463E8 739000.0 0.01 5.37944175E8 1100000.0 0.02 0.0258 0.9384 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P21 compound treatment 4.78304324E8 -6430000.0 -0.1 5.30004137E8 -6840000.0 -0.15 -0.1801 -0.978 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P22 compound treatment 4.83204134E8 -1530000.0 -0.02 5.4148993E8 4650000.0 0.11 0.0574 0.5327 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P23 compound treatment 4.59725531E8 -2.5E7 -0.39 5.02150881E8 -3.47E7 -0.78 -0.8299 -0.9479 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2098 P24 compound treatment 4.87785276E8 3050000.0 0.05 5.31610461E8 -5230000.0 -0.12 -0.05 -0.3927 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A01 compound treatment 5.86202687E8 5.59E7 0.87 6.01358379E8 4.72E7 1.07 1.3699 0.995 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A02 compound treatment 5.14977247E8 -1.53E7 -0.24 5.66154483E8 1.2E7 0.27 0.0228 0.0633 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A03 compound treatment 5.81020362E8 5.08E7 0.79 6.05129783E8 5.09E7 1.15 1.373 0.9832 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A04 compound treatment 4.79285395E8 -5.1E7 -0.79 5.44440078E8 -9750000.0 -0.22 -0.7173 -0.8705 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A05 compound treatment 5.43944393E8 1.37E7 0.21 5.89370309E8 3.52E7 0.79 0.7128 0.8661 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A06 compound treatment 4.84495964E8 -4.58E7 -0.71 5.28429893E8 -2.58E7 -0.58 -0.9158 -0.995 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A07 compound treatment 4.89235269E8 -4.1E7 -0.64 5.06934892E8 -4.73E7 -1.07 -1.2071 -0.9698 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A08 compound treatment 5.16898926E8 -1.34E7 -0.21 5.40552142E8 -1.36E7 -0.31 -0.3652 -0.9817 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A09 compound treatment 4.68144262E8 -6.21E7 -0.97 5.07377865E8 -4.68E7 -1.06 -1.4323 -0.999 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A10 compound treatment 4.96472907E8 -3.38E7 -0.53 5.15809856E8 -3.84E7 -0.87 -0.9855 -0.9713 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A11 compound treatment 5.03999384E8 -2.63E7 -0.41 4.86833231E8 -6.74E7 -1.52 -1.3657 -0.8664 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A12 compound treatment 4.85474447E8 -4.48E7 -0.7 5.02862645E8 -5.13E7 -1.16 -1.3136 -0.9704 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A13 mock treatment 5.25009883E8 -5250000.0 -0.08 5.45513445E8 -8680000.0 -0.2 -0.1966 -0.9247 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A14 mock treatment 5.26952942E8 -3310000.0 -0.05 5.63295314E8 9100000.0 0.21 0.109 0.5141 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A15 compound treatment 4.77829626E8 -5.24E7 -0.82 4.91928976E8 -6.23E7 -1.41 -1.5725 -0.9665 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A16 compound treatment 4.59017427E8 -7.12E7 -1.11 4.87267679E8 -6.69E7 -1.51 -1.8542 -0.9884 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A17 compound treatment 4.55406917E8 -7.49E7 -1.17 4.80026713E8 -7.42E7 -1.68 -2.0097 -0.9843 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A18 compound treatment 4.53020802E8 -7.72E7 -1.2 4.69407323E8 -8.48E7 -1.92 -2.2057 -0.9748 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A19 compound treatment 4.46700087E8 -8.36E7 -1.3 4.91062548E8 -6.31E7 -1.43 -1.9292 -0.9989 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A20 compound treatment 4.94049109E8 -3.62E7 -0.56 4.85448402E8 -6.87E7 -1.55 -1.4974 -0.906 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A21 compound treatment 5.12070077E8 -1.82E7 -0.28 5.07294169E8 -4.69E7 -1.06 -0.9498 -0.8657 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A22 compound treatment 5.12650828E8 -1.76E7 -0.27 5.25572554E8 -2.86E7 -0.65 -0.6513 -0.927 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A23 compound treatment 4.84439723E8 -4.58E7 -0.71 5.09131246E8 -4.51E7 -1.02 -1.2248 -0.9849 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 A24 compound treatment 4.79479067E8 -5.08E7 -0.79 5.01204848E8 -5.3E7 -1.2 -1.4061 -0.9797 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B01 compound treatment 4.72837906E8 -5.74E7 -0.89 5.0916385E8 -4.5E7 -1.02 -1.3521 -0.9979 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B02 compound treatment 4.90449057E8 -3.98E7 -0.62 4.99112976E8 -5.51E7 -1.24 -1.3187 -0.9482 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B03 compound treatment 5.22197444E8 -8060000.0 -0.13 5.56248812E8 2050000.0 0.05 -0.056 -0.4181 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B04 compound treatment 4.24462838E8 -1.06E8 -1.65 4.52153825E8 -1.02E8 -2.31 -2.7959 -0.9864 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B05 compound treatment 5.17843769E8 -1.24E7 -0.19 5.03615348E8 -5.06E7 -1.14 -0.945 -0.8152 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B06 compound treatment 4.73159472E8 -5.71E7 -0.89 5.26192021E8 -2.8E7 -0.63 -1.0764 -0.9861 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B07 compound treatment 5.37938119E8 7680000.0 0.12 5.6440184E8 1.02E7 0.23 0.2477 0.9532 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B08 compound treatment 4.80288332E8 -5.0E7 -0.78 4.68983943E8 -8.52E7 -1.93 -1.9121 -0.9206 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B09 compound treatment 4.61962604E8 -6.83E7 -1.06 5.02152509E8 -5.2E7 -1.18 -1.5839 -0.9987 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B10 compound treatment 5.18050071E8 -1.22E7 -0.19 5.28968011E8 -2.52E7 -0.57 -0.5376 -0.8945 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B11 compound treatment 4.82987647E8 -4.73E7 -0.74 4.88545703E8 -6.56E7 -1.48 -1.5698 -0.9477 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B12 compound treatment 5.07305048E8 -2.3E7 -0.36 5.26982513E8 -2.72E7 -0.61 -0.6877 -0.9667 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B13 mock treatment 5.04931774E8 -2.53E7 -0.39 5.40313223E8 -1.39E7 -0.31 -0.5008 -0.9936 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B14 mock treatment 5.26441929E8 -3820000.0 -0.06 5.3697967E8 -1.72E7 -0.39 -0.3172 -0.8058 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B15 compound treatment 3.70971798E8 -1.59E8 -2.48 3.65715402E8 -1.88E8 -4.26 -4.7664 -0.9669 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B16 compound treatment 4.59664095E8 -7.06E7 -1.1 4.77518549E8 -7.67E7 -1.73 -2.0029 -0.9759 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B17 compound treatment 4.76362381E8 -5.39E7 -0.84 4.93441064E8 -6.08E7 -1.37 -1.5645 -0.9721 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B18 compound treatment 4.64924338E8 -6.53E7 -1.02 4.6007006E8 -9.41E7 -2.13 -2.2238 -0.943 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B19 compound treatment 4.9072026E8 -3.95E7 -0.62 4.96559767E8 -5.76E7 -1.3 -1.3565 -0.9415 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B20 compound treatment 4.89990313E8 -4.03E7 -0.63 4.92080762E8 -6.21E7 -1.4 -1.4361 -0.9341 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B21 compound treatment 4.81745343E8 -4.85E7 -0.76 4.95595577E8 -5.86E7 -1.32 -1.4708 -0.9646 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B22 compound treatment 5.00421055E8 -2.98E7 -0.46 5.30829077E8 -2.34E7 -0.53 -0.702 -0.998 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B23 compound treatment 4.7222115E8 -5.8E7 -0.9 5.06365113E8 -4.78E7 -1.08 -1.4036 -0.9961 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 B24 compound treatment 4.78732866E8 -5.15E7 -0.8 4.80002704E8 -7.42E7 -1.68 -1.7532 -0.9431 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C01 compound treatment 5.1007306E8 -2.02E7 -0.31 5.33383716E8 -2.08E7 -0.47 -0.5549 -0.9808 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C02 compound treatment 4.98458647E8 -3.18E7 -0.5 5.22188814E8 -3.2E7 -0.72 -0.8617 -0.9829 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C03 compound treatment 5.31605615E8 1350000.0 0.02 5.54690065E8 495000.0 0.01 0.0227 0.9568 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C04 compound treatment 5.14234076E8 -1.6E7 -0.25 5.66938696E8 1.27E7 0.29 0.0272 0.0712 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C05 compound treatment 5.38281586E8 8020000.0 0.12 5.56421565E8 2230000.0 0.05 0.1239 0.9201 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C06 compound treatment 5.40189315E8 9930000.0 0.15 5.32514144E8 -2.17E7 -0.49 -0.2371 -0.4615 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C07 compound treatment 5.25988461E8 -4270000.0 -0.07 5.35827566E8 -1.84E7 -0.42 -0.3406 -0.8101 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C08 compound treatment 4.9630569E8 -3.4E7 -0.53 5.16586754E8 -3.76E7 -0.85 -0.975 -0.9739 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C09 compound treatment 4.91082631E8 -3.92E7 -0.61 5.26158965E8 -2.8E7 -0.63 -0.8795 -0.9998 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C10 compound treatment 5.73893241E8 4.36E7 0.68 5.50650833E8 -3540000.0 -0.08 0.4239 0.6195 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C11 mock treatment 5.73574364E8 4.33E7 0.67 5.91349504E8 3.72E7 0.84 1.0708 0.9941 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C12 mock treatment 5.46009961E8 1.58E7 0.25 5.75524775E8 2.13E7 0.48 0.5143 0.9509 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C13 compound treatment 5.26373808E8 -3890000.0 -0.06 5.18168676E8 -3.6E7 -0.81 -0.6185 -0.7576 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C14 compound treatment 5.1403861E8 -1.62E7 -0.25 5.40669976E8 -1.35E7 -0.31 -0.3948 -0.9955 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C15 mock treatment 5.67021245E8 3.68E7 0.57 5.78183165E8 2.4E7 0.54 0.7882 0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C16 mock treatment 5.64196824E8 3.39E7 0.53 5.91580601E8 3.74E7 0.84 0.9712 0.9745 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C17 compound treatment 4.97843904E8 -3.24E7 -0.5 5.16938864E8 -3.73E7 -0.84 -0.9524 -0.9701 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C18 compound treatment 4.8857711E8 -4.17E7 -0.65 5.16964597E8 -3.72E7 -0.84 -1.0541 -0.9918 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C19 compound treatment 4.96694431E8 -3.36E7 -0.52 5.41308714E8 -1.29E7 -0.29 -0.5756 -0.9618 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C20 compound treatment 5.43082433E8 1.28E7 0.2 5.61028178E8 6830000.0 0.15 0.2504 0.9919 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C21 compound treatment 5.18063928E8 -1.22E7 -0.19 5.43155477E8 -1.1E7 -0.25 -0.3107 -0.9909 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C22 compound treatment 5.28647715E8 -1610000.0 -0.03 5.68273695E8 1.41E7 0.32 0.2072 0.6493 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C23 compound treatment 4.97742559E8 -3.25E7 -0.51 5.12040854E8 -4.22E7 -0.95 -1.0318 -0.9563 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 C24 compound treatment 5.20122429E8 -1.01E7 -0.16 5.32263041E8 -2.19E7 -0.5 -0.4621 -0.8884 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D01 compound treatment 4.75149332E8 -5.51E7 -0.86 4.96930058E8 -5.73E7 -1.29 -1.5221 -0.9801 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D02 compound treatment 5.01952277E8 -2.83E7 -0.44 5.63124983E8 8930000.0 0.2 -0.1691 -0.3487 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D03 compound treatment 4.7168003E8 -5.86E7 -0.91 5.00258977E8 -5.39E7 -1.22 -1.5071 -0.9898 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D04 compound treatment 4.55274149E8 -7.5E7 -1.17 5.44885813E8 -9310000.0 -0.21 -0.9746 -0.8213 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D05 compound treatment 5.27021612E8 -3240000.0 -0.05 5.60541803E8 6350000.0 0.14 0.0658 0.4325 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D06 compound treatment 5.33788943E8 3530000.0 0.05 5.73075652E8 1.89E7 0.43 0.3406 0.7917 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D07 compound treatment 5.11006092E8 -1.93E7 -0.3 5.3474183E8 -1.95E7 -0.44 -0.5229 -0.9826 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D08 compound treatment 5.62780188E8 3.25E7 0.51 5.50038728E8 -4160000.0 -0.09 0.2918 0.5663 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D09 compound treatment 5.15416247E8 -1.48E7 -0.23 5.36762612E8 -1.74E7 -0.39 -0.4421 -0.9677 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D10 compound treatment 5.71219907E8 4.1E7 0.64 5.6951899E8 1.53E7 0.35 0.696 0.9588 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D11 mock treatment 5.48496121E8 1.82E7 0.28 5.68798016E8 1.46E7 0.33 0.4342 0.9972 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D12 mock treatment 5.63505107E8 3.32E7 0.52 5.54246461E8 51600.0 0.0 0.367 0.7087 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D13 compound treatment 5.25747308E8 -4510000.0 -0.07 5.52968743E8 -1230000.0 -0.03 -0.0693 -0.9172 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D14 compound treatment 4.73640694E8 -5.66E7 -0.88 4.13229463E8 -1.41E8 -3.19 -2.8763 -0.8701 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D15 mock treatment 5.70264809E8 4.0E7 0.62 5.66506539E8 1.23E7 0.28 0.6374 0.934 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D16 mock treatment 5.54514473E8 2.43E7 0.38 5.80775989E8 2.66E7 0.6 0.6919 0.975 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D17 compound treatment 5.34991867E8 4730000.0 0.07 5.47540416E8 -6650000.0 -0.15 -0.0542 -0.3238 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D18 compound treatment 5.02855018E8 -2.74E7 -0.43 5.2898948E8 -2.52E7 -0.57 -0.7046 -0.9899 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D19 compound treatment 5.25604186E8 -4660000.0 -0.07 5.47162802E8 -7030000.0 -0.16 -0.1637 -0.9368 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D20 compound treatment 5.44537662E8 1.43E7 0.22 5.40245889E8 -1.39E7 -0.32 -0.0657 -0.1702 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D21 compound treatment 4.90543517E8 -3.97E7 -0.62 5.38415229E8 -1.58E7 -0.36 -0.6896 -0.9658 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D22 compound treatment 4.82148032E8 -4.81E7 -0.75 4.92647184E8 -6.15E7 -1.39 -1.5135 -0.9579 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D23 compound treatment 4.81147491E8 -4.91E7 -0.76 5.16447819E8 -3.77E7 -0.85 -1.1441 -0.9985 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 D24 compound treatment 4.90904373E8 -3.94E7 -0.61 5.2044141E8 -3.38E7 -0.76 -0.9729 -0.9941 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E01 mock treatment 5.10711606E8 -1.95E7 -0.3 5.64053914E8 9860000.0 0.22 -0.0577 -0.1531 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E02 mock treatment 5.06016097E8 -2.42E7 -0.38 5.33910698E8 -2.03E7 -0.46 -0.5912 -0.9954 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E03 compound treatment 5.14045435E8 -1.62E7 -0.25 5.39733047E8 -1.45E7 -0.33 -0.4097 -0.9919 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E04 compound treatment 4.87829441E8 -4.24E7 -0.66 5.16268153E8 -3.79E7 -0.86 -1.0734 -0.9917 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E05 compound treatment 5.02406402E8 -2.79E7 -0.43 5.31905154E8 -2.23E7 -0.5 -0.663 -0.9972 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E06 compound treatment 4.92219411E8 -3.8E7 -0.59 5.29370535E8 -2.48E7 -0.56 -0.8157 -0.9996 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E07 compound treatment 5.23144929E8 -7110000.0 -0.11 5.13554614E8 -4.06E7 -0.92 -0.7278 -0.7867 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E08 compound treatment 5.09495094E8 -2.08E7 -0.32 5.2199002E8 -3.22E7 -0.73 -0.7434 -0.9333 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E09 mock treatment 5.20650132E8 -9610000.0 -0.15 5.2906572E8 -2.51E7 -0.57 -0.5074 -0.864 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E10 mock treatment 4.96691454E8 -3.36E7 -0.52 5.43828439E8 -1.04E7 -0.23 -0.5354 -0.9344 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E11 compound treatment 4.3839007E8 -9.19E7 -1.43 4.44413214E8 -1.1E8 -2.48 -2.7662 -0.9658 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E12 compound treatment 4.83266029E8 -4.7E7 -0.73 5.06575924E8 -4.76E7 -1.08 -1.2786 -0.9824 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E13 compound treatment 4.54222023E8 -7.6E7 -1.18 4.85545244E8 -6.86E7 -1.55 -1.9345 -0.9911 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E14 compound treatment 4.95764639E8 -3.45E7 -0.54 5.40309251E8 -1.39E7 -0.31 -0.6018 -0.9672 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E15 compound treatment 4.98098459E8 -3.22E7 -0.5 5.02373884E8 -5.18E7 -1.17 -1.1824 -0.9282 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E16 compound treatment 4.93012933E8 -3.72E7 -0.58 5.13133132E8 -4.11E7 -0.93 -1.0664 -0.9744 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E17 mock treatment 5.23898013E8 -6360000.0 -0.1 5.40728256E8 -1.35E7 -0.3 -0.2853 -0.8913 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E18 mock treatment 5.36389484E8 6130000.0 0.1 5.66654506E8 1.25E7 0.28 0.2666 0.8967 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E19 compound treatment 4.0659374E8 -1.24E8 -1.93 4.29620238E8 -1.25E8 -2.82 -3.3528 -0.9829 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E20 compound treatment 5.15419368E8 -1.48E7 -0.23 5.41226438E8 -1.3E7 -0.29 -0.3707 -0.9931 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E21 compound treatment 5.15095777E8 -1.52E7 -0.24 5.26562382E8 -2.76E7 -0.62 -0.6086 -0.9115 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E22 compound treatment 5.17176925E8 -1.31E7 -0.2 5.32470851E8 -2.17E7 -0.49 -0.4913 -0.9242 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E23 compound treatment 5.03646671E8 -2.66E7 -0.41 5.29784165E8 -2.44E7 -0.55 -0.6832 -0.9901 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 E24 compound treatment 4.90250544E8 -4.0E7 -0.62 5.06459966E8 -4.77E7 -1.08 -1.2035 -0.966 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F01 mock treatment 5.32433075E8 2170000.0 0.03 5.57269345E8 3070000.0 0.07 0.0731 0.9454 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F02 mock treatment 5.22935361E8 -7320000.0 -0.11 5.50494419E8 -3700000.0 -0.08 -0.1398 -0.9883 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F03 compound treatment 5.03327888E8 -2.69E7 -0.42 5.21558494E8 -3.26E7 -0.74 -0.8182 -0.9642 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F04 compound treatment 4.93630892E8 -3.66E7 -0.57 5.32694133E8 -2.15E7 -0.49 -0.747 -0.9968 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F05 compound treatment 5.71881384E8 4.16E7 0.65 5.91656309E8 3.75E7 0.85 1.0571 0.9913 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F06 compound treatment 5.34998597E8 4740000.0 0.07 5.15298414E8 -3.89E7 -0.88 -0.5694 -0.6455 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F07 compound treatment 5.4355936E8 1.33E7 0.21 5.4284065E8 -1.14E7 -0.26 -0.035 -0.106 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F08 compound treatment 5.27302169E8 -2960000.0 -0.05 5.26474414E8 -2.77E7 -0.63 -0.4756 -0.7571 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F09 mock treatment 5.33200179E8 2940000.0 0.05 5.53515671E8 -679000.0 -0.02 0.0215 0.4458 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F10 mock treatment 5.22642046E8 -7620000.0 -0.12 5.68555238E8 1.44E7 0.32 0.1456 0.4213 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F11 compound treatment 5.08524085E8 -2.17E7 -0.34 5.2050925E8 -3.37E7 -0.76 -0.7777 -0.9334 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F12 compound treatment 5.09715858E8 -2.05E7 -0.32 5.54887983E8 693000.0 0.02 -0.2152 -0.6717 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F13 compound treatment 4.96174129E8 -3.41E7 -0.53 5.20126946E8 -3.41E7 -0.77 -0.9198 -0.9835 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F14 compound treatment 4.73383999E8 -5.69E7 -0.89 4.99755153E8 -5.44E7 -1.23 -1.4964 -0.987 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F15 compound treatment 5.41900707E8 1.16E7 0.18 5.40399527E8 -1.38E7 -0.31 -0.0922 -0.2558 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F16 compound treatment 4.79782734E8 -5.05E7 -0.79 4.82887881E8 -7.13E7 -1.61 -1.6955 -0.9456 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F17 mock treatment 5.28207053E8 -2050000.0 -0.03 5.4427044E8 -9920000.0 -0.22 -0.1812 -0.7998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F18 mock treatment 5.15651246E8 -1.46E7 -0.23 5.52401097E8 -1790000.0 -0.04 -0.1896 -0.8202 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F19 compound treatment 5.08406434E8 -2.19E7 -0.34 5.29425245E8 -2.48E7 -0.56 -0.6365 -0.9716 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F20 compound treatment 4.92977945E8 -3.73E7 -0.58 5.14872593E8 -3.93E7 -0.89 -1.039 -0.9787 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F21 compound treatment 5.33180635E8 2920000.0 0.05 5.22791745E8 -3.14E7 -0.71 -0.4697 -0.6604 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F22 compound treatment 4.76439802E8 -5.38E7 -0.84 4.95151985E8 -5.9E7 -1.33 -1.5363 -0.9749 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F23 compound treatment 5.23074301E8 -7190000.0 -0.11 5.33819784E8 -2.04E7 -0.46 -0.4047 -0.8541 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 F24 compound treatment 5.13297777E8 -1.7E7 -0.26 5.3801221E8 -1.62E7 -0.37 -0.4454 -0.9873 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G01 compound treatment 5.69913805E8 3.97E7 0.62 5.60447204E8 6250000.0 0.14 0.5367 0.847 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G02 compound treatment 4.60306858E8 -7.0E7 -1.09 5.84882662E8 3.07E7 0.69 -0.28 -0.2168 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G03 mock treatment 5.39003665E8 8740000.0 0.14 5.98053517E8 4.39E7 0.99 0.7972 0.7968 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G04 mock treatment 5.25591495E8 -4670000.0 -0.07 5.964626E8 4.23E7 0.96 0.6241 0.6514 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G05 compound treatment 5.71284808E8 4.1E7 0.64 5.85823449E8 3.16E7 0.71 0.9573 0.9984 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G06 compound treatment 5.40952284E8 1.07E7 0.17 5.74235137E8 2.0E7 0.45 0.438 0.9077 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G07 compound treatment 5.45182665E8 1.49E7 0.23 5.27114278E8 -2.71E7 -0.61 -0.2684 -0.41 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G08 compound treatment 5.57743084E8 2.75E7 0.43 5.52380916E8 -1810000.0 -0.04 0.2737 0.6365 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G09 compound treatment 5.34260649E8 4000000.0 0.06 5.55171655E8 977000.0 0.02 0.0597 0.9026 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G10 compound treatment 5.32031423E8 1770000.0 0.03 5.42663098E8 -1.15E7 -0.26 -0.1648 -0.6287 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G11 compound treatment 5.14646635E8 -1.56E7 -0.24 5.23109532E8 -3.11E7 -0.7 -0.6687 -0.8995 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G12 compound treatment 5.47003839E8 1.67E7 0.26 5.70468656E8 1.63E7 0.37 0.4445 0.9858 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G13 compound treatment 5.09610511E8 -2.06E7 -0.32 5.10594789E8 -4.36E7 -0.99 -0.9242 -0.8916 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G14 compound treatment 5.15778668E8 -1.45E7 -0.23 5.7340328E8 1.92E7 0.43 0.1475 0.3014 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G15 compound treatment 4.49131356E8 -8.11E7 -1.26 4.58272973E8 -9.59E7 -2.17 -2.4264 -0.967 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G16 compound treatment 5.2448586E8 -5770000.0 -0.09 5.86819468E8 3.26E7 0.74 0.4578 0.6163 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G17 compound treatment 5.43699741E8 1.34E7 0.21 5.65669931E8 1.15E7 0.26 0.3314 0.9944 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G18 compound treatment 5.40230364E8 9970000.0 0.16 5.6635831E8 1.22E7 0.27 0.3042 0.9635 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G19 mock treatment 5.4489341E8 1.46E7 0.23 5.57471424E8 3280000.0 0.07 0.2135 0.891 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G20 mock treatment 5.53710503E8 2.35E7 0.37 5.69991467E8 1.58E7 0.36 0.5107 0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G21 compound treatment 5.49267341E8 1.9E7 0.3 5.64617093E8 1.04E7 0.24 0.3759 0.9936 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G22 compound treatment 5.30416843E8 157000.0 0.0 5.67498516E8 1.33E7 0.3 0.2143 0.7128 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G23 compound treatment 5.16031469E8 -1.42E7 -0.22 5.386365E8 -1.56E7 -0.35 -0.4053 -0.9752 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 G24 compound treatment 5.16480714E8 -1.38E7 -0.21 5.5054889E8 -3650000.0 -0.08 -0.21 -0.9136 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H01 compound treatment 5.2215973E8 -8100000.0 -0.13 5.5133269E8 -2860000.0 -0.06 -0.135 -0.9518 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H02 compound treatment 5.47148594E8 1.69E7 0.26 5.63573028E8 9380000.0 0.21 0.3359 0.9943 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H03 mock treatment 6.03980282E8 7.37E7 1.15 5.86509665E8 3.23E7 0.73 1.3284 0.9761 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H04 mock treatment 5.94087436E8 6.38E7 0.99 5.80045184E8 2.59E7 0.58 1.1161 0.9679 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H05 compound treatment 5.42940663E8 1.27E7 0.2 5.47898817E8 -6300000.0 -0.14 0.0391 0.1604 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H06 compound treatment 5.67274432E8 3.7E7 0.58 5.60064874E8 5870000.0 0.13 0.5015 0.8477 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H07 compound treatment 4.59063552E8 -7.12E7 -1.11 5.17122674E8 -3.71E7 -0.84 -1.3766 -0.9904 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H08 compound treatment 5.71947108E8 4.17E7 0.65 5.81468541E8 2.73E7 0.62 0.895 0.9997 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H09 compound treatment 4.92284559E8 -3.8E7 -0.59 5.16511888E8 -3.77E7 -0.85 -1.0205 -0.9841 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H10 compound treatment 5.47693006E8 1.74E7 0.27 5.77685601E8 2.35E7 0.53 0.5674 0.9515 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H11 compound treatment 5.73239446E8 4.3E7 0.67 5.66321418E8 1.21E7 0.27 0.6672 0.9223 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H12 compound treatment 5.57928712E8 2.77E7 0.43 5.58447884E8 4250000.0 0.1 0.3727 0.8441 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H13 compound treatment 5.11527271E8 -1.87E7 -0.29 5.00843843E8 -5.34E7 -1.21 -1.0589 -0.8536 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H14 compound treatment 5.18774762E8 -1.15E7 -0.18 5.57787562E8 3590000.0 0.08 -0.0691 -0.3516 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H15 compound treatment 5.8213594E8 5.19E7 0.81 5.71823304E8 1.76E7 0.4 0.8531 0.9469 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H16 compound treatment 5.41602445E8 1.13E7 0.18 5.40175266E8 -1.4E7 -0.32 -0.0991 -0.2732 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H17 compound treatment 4.31649069E8 -9.86E7 -1.54 5.10602191E8 -4.36E7 -0.99 -1.7827 -0.977 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H18 compound treatment 5.18764519E8 -1.15E7 -0.18 5.62089585E8 7890000.0 0.18 -4.0E-4 -0.0018 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H19 mock treatment 5.57284127E8 2.7E7 0.42 5.5789075E8 3700000.0 0.08 0.3567 0.8312 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H20 mock treatment 5.51807494E8 2.15E7 0.34 5.89907178E8 3.57E7 0.81 0.808 0.9244 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H21 compound treatment 5.43015056E8 1.28E7 0.2 5.5297261E8 -1220000.0 -0.03 0.121 0.603 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H22 compound treatment 5.31813832E8 1550000.0 0.02 5.69670335E8 1.55E7 0.35 0.2644 0.7542 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H23 compound treatment 5.28744718E8 -1520000.0 -0.02 5.81205931E8 2.7E7 0.61 0.415 0.6793 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 H24 compound treatment 5.05422024E8 -2.48E7 -0.39 5.48223803E8 -5970000.0 -0.13 -0.369 -0.9005 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I01 compound treatment 5.02353684E8 -2.79E7 -0.43 5.1452925E8 -3.97E7 -0.9 -0.9412 -0.9448 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I02 compound treatment 4.38491708E8 -9.18E7 -1.43 5.11107456E8 -4.31E7 -0.97 -1.6993 -0.9825 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I03 compound treatment 4.63994355E8 -6.63E7 -1.03 5.00140981E8 -5.41E7 -1.22 -1.5937 -0.9965 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I04 compound treatment 4.80363168E8 -4.99E7 -0.78 5.17220306E8 -3.7E7 -0.84 -1.1404 -0.9993 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I05 mock treatment 4.92016494E8 -3.82E7 -0.6 5.44078817E8 -1.01E7 -0.23 -0.5829 -0.9135 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I06 mock treatment 5.08171794E8 -2.21E7 -0.34 5.558854E8 1690000.0 0.04 -0.2163 -0.6247 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I07 compound treatment 4.70307405E8 -6.0E7 -0.93 4.732077E8 -8.1E7 -1.83 -1.9545 -0.9512 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I08 compound treatment 5.27094312E8 -3170000.0 -0.05 5.20403622E8 -3.38E7 -0.76 -0.5749 -0.7512 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I09 compound treatment 4.68455141E8 -6.18E7 -0.96 4.82715567E8 -7.15E7 -1.62 -1.823 -0.9694 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I10 compound treatment 4.99479491E8 -3.08E7 -0.48 5.24375436E8 -2.98E7 -0.67 -0.8155 -0.9861 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I11 compound treatment 4.83984745E8 -4.63E7 -0.72 4.7389446E8 -8.03E7 -1.81 -1.7929 -0.9182 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I12 compound treatment 5.26774704E8 -3490000.0 -0.05 5.17076005E8 -3.71E7 -0.84 -0.6316 -0.7513 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I13 compound treatment 4.87649477E8 -4.26E7 -0.66 4.87697736E8 -6.65E7 -1.5 -1.532 -0.9325 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I14 compound treatment 4.47879243E8 -8.24E7 -1.28 4.66294578E8 -8.79E7 -1.99 -2.312 -0.9776 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I15 compound treatment 4.51706665E8 -7.86E7 -1.22 4.6653299E8 -8.77E7 -1.98 -2.2661 -0.9732 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I16 compound treatment 4.76737049E8 -5.35E7 -0.83 5.0392178E8 -5.03E7 -1.14 -1.3929 -0.9884 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I17 compound treatment 4.64418662E8 -6.58E7 -1.03 5.05618389E8 -4.86E7 -1.1 -1.5015 -0.9994 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I18 compound treatment 4.76367436E8 -5.39E7 -0.84 5.0303146E8 -5.12E7 -1.16 -1.4112 -0.9876 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I19 compound treatment 4.66992343E8 -6.33E7 -0.99 4.83218494E8 -7.1E7 -1.6 -1.8311 -0.9726 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I20 compound treatment 4.51749262E8 -7.85E7 -1.22 4.63117929E8 -9.11E7 -2.06 -2.3202 -0.9691 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I21 mock treatment 5.26958261E8 -3300000.0 -0.05 5.17401988E8 -3.68E7 -0.83 -0.6243 -0.7494 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I22 mock treatment 4.9895238E8 -3.13E7 -0.49 5.29213902E8 -2.5E7 -0.56 -0.744 -0.9973 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I23 compound treatment 4.78551582E8 -5.17E7 -0.81 4.74808244E8 -7.94E7 -1.79 -1.8382 -0.9347 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 I24 compound treatment 5.00790147E8 -2.95E7 -0.46 4.83755825E8 -7.04E7 -1.59 -1.4502 -0.8753 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J01 compound treatment 4.2458982E8 -1.06E8 -1.65 4.56679341E8 -9.75E7 -2.2 -2.7222 -0.9897 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J02 compound treatment 4.75086748E8 -5.52E7 -0.86 5.25916343E8 -2.83E7 -0.64 -1.0596 -0.9894 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J03 compound treatment 4.94273365E8 -3.6E7 -0.56 5.24701344E8 -2.95E7 -0.67 -0.8677 -0.9963 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J04 compound treatment 4.96424607E8 -3.38E7 -0.53 5.18644722E8 -3.56E7 -0.8 -0.9408 -0.9791 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J05 mock treatment 5.18692038E8 -1.16E7 -0.18 5.67493984E8 1.33E7 0.3 0.0851 0.2429 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J06 mock treatment 5.05204155E8 -2.51E7 -0.39 5.8183281E8 2.76E7 0.62 0.1657 0.225 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J07 compound treatment 4.76076771E8 -5.42E7 -0.84 5.22471907E8 -3.17E7 -0.72 -1.1037 -0.9967 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J08 compound treatment 4.74319076E8 -5.59E7 -0.87 5.00860287E8 -5.33E7 -1.21 -1.4684 -0.9873 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J09 compound treatment 4.55265782E8 -7.5E7 -1.17 4.85586074E8 -6.86E7 -1.55 -1.9224 -0.9902 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J10 compound treatment 4.7295967E8 -5.73E7 -0.89 5.03750076E8 -5.04E7 -1.14 -1.4372 -0.9927 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J11 compound treatment 4.55889208E8 -7.44E7 -1.16 4.84459398E8 -6.97E7 -1.58 -1.9335 -0.9885 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J12 compound treatment 4.86124376E8 -4.41E7 -0.69 5.50035097E8 -4160000.0 -0.09 -0.5526 -0.7964 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J13 compound treatment 4.51552329E8 -7.87E7 -1.23 4.44227207E8 -1.1E8 -2.49 -2.6242 -0.947 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J14 compound treatment 4.68281442E8 -6.2E7 -0.97 4.83503715E8 -7.07E7 -1.6 -1.8123 -0.9709 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J15 compound treatment 4.72175869E8 -5.81E7 -0.9 5.14163023E8 -4.0E7 -0.9 -1.2795 -1.0 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J16 compound treatment 4.90019938E8 -4.02E7 -0.63 5.04821321E8 -4.94E7 -1.12 -1.2322 -0.9628 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J17 compound treatment 4.87530908E8 -4.27E7 -0.67 5.1348102E8 -4.07E7 -0.92 -1.1212 -0.9874 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J18 compound treatment 4.53646931E8 -7.66E7 -1.19 4.44345513E8 -1.1E8 -2.48 -2.5993 -0.9436 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J19 compound treatment 4.49319109E8 -8.09E7 -1.26 4.4204392E8 -1.12E8 -2.53 -2.6837 -0.948 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J20 compound treatment 4.45253848E8 -8.5E7 -1.32 4.69949969E8 -8.42E7 -1.9 -2.2825 -0.9842 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J21 mock treatment 5.132577E8 -1.7E7 -0.26 5.3553771E8 -1.87E7 -0.42 -0.4854 -0.9749 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J22 mock treatment 5.13249016E8 -1.7E7 -0.26 5.33582468E8 -2.06E7 -0.47 -0.5168 -0.9642 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J23 compound treatment 5.12655241E8 -1.76E7 -0.27 5.24305728E8 -2.99E7 -0.68 -0.6715 -0.9211 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 J24 compound treatment 4.42362362E8 -8.79E7 -1.37 4.26092614E8 -1.28E8 -2.9 -3.0152 -0.9415 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K01 compound treatment 4.8957395E8 -4.07E7 -0.63 4.79067368E8 -7.51E7 -1.7 -1.6487 -0.9097 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K02 compound treatment 4.41200966E8 -8.91E7 -1.39 4.70349086E8 -8.38E7 -1.89 -2.3208 -0.9882 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K03 compound treatment 5.39692482E8 9430000.0 0.15 5.34036363E8 -2.02E7 -0.46 -0.2183 -0.4559 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K04 compound treatment 4.79935114E8 -5.03E7 -0.78 4.95810217E8 -5.84E7 -1.32 -1.4873 -0.9691 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K05 compound treatment 5.01946872E8 -2.83E7 -0.44 5.35808228E8 -1.84E7 -0.42 -0.6057 -0.9996 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K06 compound treatment 4.62210629E8 -6.8E7 -1.06 4.1874843E8 -1.35E8 -3.06 -2.914 -0.8995 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K07 mock treatment 5.07004864E8 -2.33E7 -0.36 5.63651621E8 9460000.0 0.21 -0.105 -0.2497 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K08 mock treatment 5.19016054E8 -1.12E7 -0.18 5.53369587E8 -825000.0 -0.02 -0.137 -0.778 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K09 compound treatment 2.93981872E8 -2.36E8 -3.68 2.47273804E8 -3.07E8 -6.94 -7.5071 -0.956 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K10 compound treatment 5.12561938E8 -1.77E7 -0.28 5.17614065E8 -3.66E7 -0.83 -0.7795 -0.8945 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K11 compound treatment 4.97999811E8 -3.23E7 -0.5 4.70558495E8 -8.36E7 -1.89 -1.6919 -0.865 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K12 compound treatment 5.06340339E8 -2.39E7 -0.37 5.0823065E8 -4.6E7 -1.04 -0.998 -0.9043 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K13 compound treatment 4.86634632E8 -4.36E7 -0.68 4.8103655E8 -7.32E7 -1.65 -1.6496 -0.9228 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K14 compound treatment 4.30564897E8 -9.97E7 -1.55 4.59376435E8 -9.48E7 -2.14 -2.6133 -0.9875 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K15 mock treatment 5.16515321E8 -1.37E7 -0.21 5.36176029E8 -1.8E7 -0.41 -0.4393 -0.9549 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K16 mock treatment 5.20339669E8 -9920000.0 -0.15 5.33292811E8 -2.09E7 -0.47 -0.4433 -0.8919 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K17 compound treatment 4.69936133E8 -6.03E7 -0.94 4.62494833E8 -9.17E7 -2.07 -2.1298 -0.936 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K18 compound treatment 4.79903E8 -5.04E7 -0.78 5.11505939E8 -4.27E7 -0.96 -1.2368 -0.9947 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K19 compound treatment 4.57751665E8 -7.25E7 -1.13 4.95281195E8 -5.89E7 -1.33 -1.7401 -0.9966 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K20 compound treatment 4.6744962E8 -6.28E7 -0.98 4.8980037E8 -6.44E7 -1.46 -1.7208 -0.9813 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K21 compound treatment 4.91545468E8 -3.87E7 -0.6 5.06335721E8 -4.79E7 -1.08 -1.1912 -0.9619 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K22 compound treatment 4.54342302E8 -7.59E7 -1.18 4.33023898E8 -1.21E8 -2.74 -2.7725 -0.9295 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K23 mock treatment 5.01418913E8 -2.88E7 -0.45 5.03709395E8 -5.05E7 -1.14 -1.1244 -0.917 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 K24 mock treatment 5.00625203E8 -2.96E7 -0.46 5.17182851E8 -3.7E7 -0.84 -0.9179 -0.9607 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L01 compound treatment 4.42559252E8 -8.77E7 -1.37 4.8053537E8 -7.37E7 -1.66 -2.1431 -0.9952 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L02 compound treatment 4.55596921E8 -7.47E7 -1.16 4.693231E8 -8.49E7 -1.92 -2.1786 -0.9713 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L03 compound treatment 4.43807378E8 -8.65E7 -1.35 4.72947024E8 -8.12E7 -1.84 -2.2506 -0.9884 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L04 compound treatment 4.21185662E8 -1.09E8 -1.7 4.71656888E8 -8.25E7 -1.87 -2.5203 -0.9989 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L05 compound treatment 5.27423453E8 -2840000.0 -0.04 5.4454902E8 -9650000.0 -0.22 -0.1854 -0.8335 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L06 compound treatment 4.8542923E8 -4.48E7 -0.7 5.18052782E8 -3.61E7 -0.82 -1.0713 -0.997 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L07 mock treatment 5.34258785E8 4000000.0 0.06 5.45126818E8 -9070000.0 -0.2 -0.1009 -0.4709 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L08 mock treatment 5.15438863E8 -1.48E7 -0.23 5.34788563E8 -1.94E7 -0.44 -0.4734 -0.9551 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L09 compound treatment 4.37533102E8 -9.27E7 -1.44 4.88452677E8 -6.57E7 -1.49 -2.0719 -0.9999 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L10 compound treatment 4.37872574E8 -9.24E7 -1.44 4.86413422E8 -6.78E7 -1.53 -2.1007 -0.9995 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L11 compound treatment 4.67267265E8 -6.3E7 -0.98 4.96980239E8 -5.72E7 -1.29 -1.6081 -0.9907 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L12 compound treatment 3.4928099E8 -1.81E8 -2.82 3.51426491E8 -2.03E8 -4.58 -5.2337 -0.9728 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L13 compound treatment 5.18699254E8 -1.16E7 -0.18 5.30342373E8 -2.39E7 -0.54 -0.5085 -0.8947 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L14 compound treatment 4.97296207E8 -3.3E7 -0.51 5.04388626E8 -4.98E7 -1.13 -1.159 -0.9368 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L15 mock treatment 5.11162463E8 -1.91E7 -0.3 5.43482132E8 -1.07E7 -0.24 -0.3815 -0.9948 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L16 mock treatment 5.45139774E8 1.49E7 0.23 5.71406014E8 1.72E7 0.39 0.4389 0.9694 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L17 compound treatment 4.86448075E8 -4.38E7 -0.68 4.86514088E8 -6.77E7 -1.53 -1.5641 -0.9339 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L18 compound treatment 4.48789811E8 -8.15E7 -1.27 4.77369341E8 -7.68E7 -1.74 -2.125 -0.9881 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L19 compound treatment 4.7554202E8 -5.47E7 -0.85 4.92126489E8 -6.21E7 -1.4 -1.5945 -0.9715 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L20 compound treatment 4.68105182E8 -6.22E7 -0.97 4.84601103E8 -6.96E7 -1.57 -1.7967 -0.9728 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L21 compound treatment 4.45455446E8 -8.48E7 -1.32 4.50119992E8 -1.04E8 -2.35 -2.5972 -0.9628 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L22 compound treatment 4.87252667E8 -4.3E7 -0.67 4.70193552E8 -8.4E7 -1.9 -1.8161 -0.9021 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L23 mock treatment 5.26354505E8 -3910000.0 -0.06 5.28465347E8 -2.57E7 -0.58 -0.4542 -0.7768 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 L24 mock treatment 5.03946528E8 -2.63E7 -0.41 5.25865806E8 -2.83E7 -0.64 -0.7425 -0.9768 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M01 compound treatment 5.10144313E8 -2.01E7 -0.31 5.22408206E8 -3.18E7 -0.72 -0.7295 -0.9308 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M02 compound treatment 5.11338638E8 -1.89E7 -0.29 4.91725684E8 -6.25E7 -1.41 -1.2067 -0.8367 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M03 compound treatment 5.37323608E8 7060000.0 0.11 5.44534421E8 -9660000.0 -0.22 -0.0766 -0.3132 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M04 compound treatment 4.98546135E8 -3.17E7 -0.49 5.18478804E8 -3.57E7 -0.81 -0.9201 -0.9722 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M05 compound treatment 5.04259449E8 -2.6E7 -0.4 5.15782306E8 -3.84E7 -0.87 -0.9002 -0.9397 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M06 compound treatment 5.19424237E8 -1.08E7 -0.17 5.28204898E8 -2.6E7 -0.59 -0.5347 -0.8749 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M07 compound treatment 4.93519303E8 -3.67E7 -0.57 4.82810266E8 -7.14E7 -1.61 -1.5454 -0.9028 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M08 compound treatment 5.03325605E8 -2.69E7 -0.42 5.16495024E8 -3.77E7 -0.85 -0.8991 -0.9467 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M09 mock treatment 4.99676222E8 -3.06E7 -0.48 5.66905345E8 1.27E7 0.29 -0.1337 -0.2404 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M10 mock treatment 5.26682194E8 -3580000.0 -0.06 5.50719524E8 -3480000.0 -0.08 -0.0949 -0.9859 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M11 compound treatment 3.67032673E8 -1.63E8 -2.54 3.96364932E8 -1.58E8 -3.57 -4.32 -0.9862 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M12 compound treatment 4.90295982E8 -4.0E7 -0.62 4.9328713E8 -6.09E7 -1.38 -1.4135 -0.9356 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M13 mock treatment 5.14546519E8 -1.57E7 -0.24 5.12975568E8 -4.12E7 -0.93 -0.8318 -0.8636 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M14 mock treatment 5.35321977E8 5060000.0 0.08 5.2446563E8 -2.97E7 -0.67 -0.4193 -0.6199 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M15 compound treatment 4.721957E8 -5.81E7 -0.9 4.62600153E8 -9.16E7 -2.07 -2.1033 -0.9311 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M16 compound treatment 4.60137528E8 -7.01E7 -1.09 4.63337801E8 -9.09E7 -2.05 -2.2243 -0.9564 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M17 compound treatment 4.76225628E8 -5.4E7 -0.84 4.5503364E8 -9.92E7 -2.24 -2.1798 -0.9106 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M18 compound treatment 5.32977193E8 2720000.0 0.04 5.45993173E8 -8200000.0 -0.19 -0.1011 -0.5319 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M19 compound treatment 5.28196392E8 -2060000.0 -0.03 5.00515426E8 -5.37E7 -1.21 -0.8806 -0.7256 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M20 compound treatment 4.830573E8 -4.72E7 -0.74 4.83259729E8 -7.09E7 -1.6 -1.6535 -0.9375 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M21 compound treatment 4.97572761E8 -3.27E7 -0.51 4.7988153E8 -7.43E7 -1.68 -1.5476 -0.8818 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M22 compound treatment 4.89765179E8 -4.05E7 -0.63 4.6120736E8 -9.3E7 -2.1 -1.932 -0.8805 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M23 compound treatment 4.69817241E8 -6.04E7 -0.94 4.61295895E8 -9.29E7 -2.1 -2.1503 -0.9345 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 M24 compound treatment 4.62877938E8 -6.74E7 -1.05 4.68149391E8 -8.6E7 -1.94 -2.1172 -0.9581 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N01 compound treatment 5.50492711E8 2.02E7 0.32 5.16434244E8 -3.78E7 -0.85 -0.3806 -0.4184 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N02 compound treatment 5.17942285E8 -1.23E7 -0.19 5.45860173E8 -8330000.0 -0.19 -0.2689 -1.0 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N03 compound treatment 5.26237496E8 -4020000.0 -0.06 5.23330945E8 -3.09E7 -0.7 -0.5375 -0.7675 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N04 compound treatment 4.97268198E8 -3.3E7 -0.51 4.89628503E8 -6.46E7 -1.46 -1.3952 -0.9018 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N05 compound treatment 4.90558677E8 -3.97E7 -0.62 5.31655234E8 -2.25E7 -0.51 -0.7975 -0.9954 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N06 compound treatment 4.85506425E8 -4.48E7 -0.7 5.28125168E8 -2.61E7 -0.59 -0.9095 -0.9965 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N07 compound treatment 4.94201419E8 -3.61E7 -0.56 5.43841416E8 -1.04E7 -0.23 -0.5626 -0.9247 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N08 compound treatment 5.00344988E8 -2.99E7 -0.47 5.29962093E8 -2.42E7 -0.55 -0.7167 -0.9968 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N09 mock treatment 5.13247674E8 -1.7E7 -0.26 5.52647539E8 -1550000.0 -0.03 -0.2121 -0.7935 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N10 mock treatment 5.29651056E8 -609000.0 -0.01 5.42742584E8 -1.15E7 -0.26 -0.1897 -0.7325 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N11 compound treatment 5.67277466E8 3.7E7 0.58 5.33538317E8 -2.07E7 -0.47 0.0776 0.1046 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N12 compound treatment 3.9205564E8 -1.38E8 -2.15 3.94819129E8 -1.59E8 -3.6 -4.0691 -0.9697 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N13 mock treatment 5.30704896E8 445000.0 0.01 5.45494481E8 -8700000.0 -0.2 -0.1341 -0.6818 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N14 mock treatment 5.6141747E8 3.12E7 0.49 5.53532676E8 -662000.0 -0.01 0.3326 0.685 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N15 compound treatment 4.85875671E8 -4.44E7 -0.69 4.96906214E8 -5.73E7 -1.29 -1.4044 -0.9568 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N16 compound treatment 5.03312169E8 -2.69E7 -0.42 5.1479971E8 -3.94E7 -0.89 -0.9264 -0.9411 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N17 compound treatment 5.28451327E8 -1810000.0 -0.03 5.28428201E8 -2.58E7 -0.58 -0.4317 -0.7404 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N18 compound treatment 4.73543861E8 -5.67E7 -0.88 4.95300759E8 -5.89E7 -1.33 -1.5658 -0.9802 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N19 compound treatment 4.76477094E8 -5.38E7 -0.84 5.1624415E8 -3.8E7 -0.86 -1.1988 -0.9999 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N20 compound treatment 4.72252367E8 -5.8E7 -0.9 4.85214181E8 -6.9E7 -1.56 -1.7412 -0.9664 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N21 compound treatment 5.00095551E8 -3.02E7 -0.47 4.98208173E8 -5.6E7 -1.27 -1.2269 -0.909 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N22 compound treatment 4.53344665E8 -7.69E7 -1.2 4.98800352E8 -5.54E7 -1.25 -1.7324 -0.9998 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N23 compound treatment 4.99209763E8 -3.11E7 -0.48 5.05070512E8 -4.91E7 -1.11 -1.127 -0.9307 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 N24 compound treatment 4.80674926E8 -4.96E7 -0.77 4.74910969E8 -7.93E7 -1.79 -1.8131 -0.9292 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O01 compound treatment 5.63895308E8 3.36E7 0.52 5.70303175E8 1.61E7 0.36 0.6279 0.9842 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O02 compound treatment 3.5859505E8 -1.72E8 -2.67 3.5357446E8 -2.01E8 -4.53 -5.0967 -0.9683 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O03 compound treatment 5.40897263E8 1.06E7 0.17 5.62026778E8 7830000.0 0.18 0.2423 0.9995 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O04 compound treatment 4.81216324E8 -4.9E7 -0.76 5.08058746E8 -4.61E7 -1.04 -1.2774 -0.9883 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O05 compound treatment 5.34724701E8 4460000.0 0.07 5.47834214E8 -6360000.0 -0.14 -0.0525 -0.3286 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O06 compound treatment 4.61828877E8 -6.84E7 -1.07 5.05645289E8 -4.85E7 -1.1 -1.5295 -0.9999 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O07 compound treatment 5.04341137E8 -2.59E7 -0.4 5.2293406E8 -3.13E7 -0.71 -0.785 -0.9648 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O08 compound treatment 4.74866813E8 -5.54E7 -0.86 5.64213261E8 1.0E7 0.23 -0.45 -0.5045 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O09 compound treatment 4.99561087E8 -3.07E7 -0.48 5.33959796E8 -2.02E7 -0.46 -0.6615 -0.9998 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O10 compound treatment 5.04342703E8 -2.59E7 -0.4 5.40773873E8 -1.34E7 -0.3 -0.4999 -0.9901 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O11 mock treatment 5.46814527E8 1.66E7 0.26 5.46915919E8 -7280000.0 -0.16 0.066 0.2158 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O12 mock treatment 5.13763779E8 -1.65E7 -0.26 5.52000206E8 -2190000.0 -0.05 -0.2168 -0.8283 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O13 compound treatment 4.92629239E8 -3.76E7 -0.59 5.20622719E8 -3.36E7 -0.76 -0.951 -0.9919 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O14 compound treatment 4.92098521E8 -3.82E7 -0.59 5.52875388E8 -1320000.0 -0.03 -0.4414 -0.7416 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O15 compound treatment 4.91792806E8 -3.85E7 -0.6 4.93045221E8 -6.11E7 -1.38 -1.4009 -0.93 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O16 compound treatment 4.95456326E8 -3.48E7 -0.54 5.31774133E8 -2.24E7 -0.51 -0.7416 -0.9994 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O17 compound treatment 5.08996439E8 -2.13E7 -0.33 5.41956537E8 -1.22E7 -0.28 -0.4298 -0.996 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O18 compound treatment 5.08992122E8 -2.13E7 -0.33 5.19590142E8 -3.46E7 -0.78 -0.7872 -0.9269 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O19 compound treatment 5.11816121E8 -1.84E7 -0.29 5.36325443E8 -1.79E7 -0.4 -0.4887 -0.9861 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O20 compound treatment 5.23005953E8 -7250000.0 -0.11 5.35604649E8 -1.86E7 -0.42 -0.377 -0.8665 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O21 compound treatment 5.27833539E8 -2430000.0 -0.04 5.44339024E8 -9860000.0 -0.22 -0.1842 -0.8154 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O22 compound treatment 5.34860213E8 4600000.0 0.07 5.12390371E8 -4.18E7 -0.94 -0.6174 -0.6516 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O23 compound treatment 4.72365324E8 -5.79E7 -0.9 4.9770772E8 -5.65E7 -1.28 -1.5403 -0.9855 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 O24 compound treatment 4.95492075E8 -3.48E7 -0.54 5.11902185E8 -4.23E7 -0.96 -1.0588 -0.9638 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P01 compound treatment 4.63589606E8 -6.67E7 -1.04 4.7955433E8 -7.46E7 -1.69 -1.9271 -0.9728 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P02 compound treatment 5.12644852E8 -1.76E7 -0.27 5.4025552E8 -1.39E7 -0.32 -0.4168 -0.9976 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P03 compound treatment 5.23012452E8 -7250000.0 -0.11 5.7119031E8 1.7E7 0.38 0.1918 0.479 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P04 compound treatment 5.04594296E8 -2.57E7 -0.4 5.3063173E8 -2.36E7 -0.53 -0.6592 -0.99 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P05 compound treatment 5.08615465E8 -2.16E7 -0.34 5.75344153E8 2.11E7 0.48 0.0996 0.1703 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P06 compound treatment 5.15703156E8 -1.46E7 -0.23 5.86039041E8 3.18E7 0.72 0.3486 0.462 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P07 compound treatment 5.49808338E8 1.95E7 0.3 5.52531651E8 -1660000.0 -0.04 0.1887 0.6151 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P08 compound treatment 5.49669652E8 1.94E7 0.3 5.82347332E8 2.82E7 0.64 0.6637 0.9421 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P09 compound treatment 5.49439839E8 1.92E7 0.3 5.4527859E8 -8920000.0 -0.2 0.0688 0.1908 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P10 compound treatment 5.4953513E8 1.93E7 0.3 5.7230388E8 1.81E7 0.41 0.5017 0.9884 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P11 mock treatment 5.37143358E8 6880000.0 0.11 5.79658716E8 2.55E7 0.58 0.4827 0.8247 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P12 mock treatment 5.59230059E8 2.9E7 0.45 5.84720283E8 3.05E7 0.69 0.8069 0.9788 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P13 compound treatment 5.35495725E8 5240000.0 0.08 5.48523799E8 -5670000.0 -0.13 -0.033 -0.217 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P14 compound treatment 5.08905859E8 -2.14E7 -0.33 5.42300201E8 -1.19E7 -0.27 -0.4253 -0.9944 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P15 compound treatment 5.26805325E8 -3450000.0 -0.05 5.49526934E8 -4670000.0 -0.11 -0.1126 -0.9512 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P16 compound treatment 5.11483109E8 -1.88E7 -0.29 5.10248204E8 -4.39E7 -0.99 -0.9091 -0.8781 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P17 compound treatment 5.44175307E8 1.39E7 0.22 5.6215195E8 7960000.0 0.18 0.2804 0.9957 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P18 compound treatment 5.42901428E8 1.26E7 0.2 5.5796139E8 3770000.0 0.09 0.1994 0.9296 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P19 compound treatment 5.36547563E8 6290000.0 0.1 5.38295826E8 -1.59E7 -0.36 -0.1848 -0.4963 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P20 compound treatment 5.24347925E8 -5910000.0 -0.09 5.40362875E8 -1.38E7 -0.31 -0.2862 -0.8781 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P21 compound treatment 5.23671709E8 -6590000.0 -0.1 5.50634387E8 -3560000.0 -0.08 -0.1295 -0.9928 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P22 compound treatment 4.29339309E8 -1.01E8 -1.57 4.43710028E8 -1.1E8 -2.5 -2.8771 -0.9751 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P23 compound treatment 4.90042771E8 -4.02E7 -0.63 5.25526879E8 -2.87E7 -0.65 -0.9011 -0.9999 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2100 P24 compound treatment 3.72810394E8 -1.57E8 -2.45 4.63936776E8 -9.03E7 -2.04 -3.1765 -0.9958 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A01 compound treatment 5.96139614E8 6.44E7 1.0 5.98050891E8 3.23E7 0.73 1.2252 0.9878 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A02 compound treatment 5.97751018E8 6.6E7 1.03 5.96633805E8 3.09E7 0.7 1.2203 0.9821 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A03 compound treatment 5.71698587E8 4.0E7 0.62 5.84477857E8 1.87E7 0.42 0.7391 0.9822 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A04 compound treatment 5.65983379E8 3.42E7 0.53 6.04537555E8 3.88E7 0.88 0.9967 0.9717 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A05 compound treatment 5.60683535E8 2.9E7 0.45 5.9008703E8 2.43E7 0.55 0.7074 0.9952 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A06 compound treatment 5.1431866E8 -1.74E7 -0.27 5.71398691E8 5630000.0 0.13 -0.1019 -0.34 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A07 compound treatment 5.1677117E8 -1.5E7 -0.23 5.64687764E8 -1080000.0 -0.02 -0.1821 -0.7771 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A08 compound treatment 5.26003295E8 -5730000.0 -0.09 5.87542391E8 2.18E7 0.49 0.2848 0.5695 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A09 compound treatment 5.26304714E8 -5430000.0 -0.08 5.65510921E8 -260000.0 -0.01 -0.0639 -0.7544 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A10 compound treatment 5.22196599E8 -9540000.0 -0.15 5.32340382E8 -3.34E7 -0.76 -0.6393 -0.8302 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A11 compound treatment 5.33523217E8 1790000.0 0.03 5.69345698E8 3570000.0 0.08 0.0768 0.8991 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A12 compound treatment 4.95583343E8 -3.62E7 -0.56 5.55060158E8 -1.07E7 -0.24 -0.5693 -0.9289 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A13 mock treatment 5.26777169E8 -4960000.0 -0.08 5.39894585E8 -2.59E7 -0.58 -0.4681 -0.7936 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A14 mock treatment 5.31831436E8 98000.0 0.0 5.82200575E8 1.64E7 0.37 0.2636 0.71 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A15 compound treatment 5.1428811E8 -1.74E7 -0.27 5.13494355E8 -5.23E7 -1.18 -1.0276 -0.8476 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A16 compound treatment 4.97100506E8 -3.46E7 -0.54 5.29483519E8 -3.63E7 -0.82 -0.9613 -0.9793 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A17 compound treatment 4.81910491E8 -4.98E7 -0.78 5.15474568E8 -5.03E7 -1.14 -1.3525 -0.9827 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A18 compound treatment 4.99898259E8 -3.18E7 -0.5 5.31441888E8 -3.43E7 -0.78 -0.8992 -0.9766 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A19 compound treatment 5.13686148E8 -1.8E7 -0.28 5.26546223E8 -3.92E7 -0.89 -0.8256 -0.8878 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A20 compound treatment 4.96800426E8 -3.49E7 -0.54 5.41791507E8 -2.4E7 -0.54 -0.768 -1.0 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A21 compound treatment 4.65546649E8 -6.62E7 -1.03 5.13863983E8 -5.19E7 -1.17 -1.5585 -0.9979 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A22 compound treatment 4.93656214E8 -3.81E7 -0.59 5.25849435E8 -3.99E7 -0.9 -1.0574 -0.9793 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A23 compound treatment 4.75430599E8 -5.63E7 -0.88 5.03642364E8 -6.21E7 -1.4 -1.613 -0.9743 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 A24 compound treatment 4.75509581E8 -5.62E7 -0.88 5.18418957E8 -4.74E7 -1.07 -1.376 -0.995 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B01 compound treatment 4.95921133E8 -3.58E7 -0.56 5.12169817E8 -5.36E7 -1.21 -1.251 -0.938 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B02 compound treatment 5.14546865E8 -1.72E7 -0.27 5.35426578E8 -3.03E7 -0.69 -0.6742 -0.9158 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B03 compound treatment 4.88959906E8 -4.28E7 -0.67 5.4373815E8 -2.2E7 -0.5 -0.8232 -0.9897 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B04 compound treatment 5.08565519E8 -2.32E7 -0.36 5.78449671E8 1.27E7 0.29 -0.0526 -0.1141 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B05 compound treatment 4.89994682E8 -4.17E7 -0.65 5.33323961E8 -3.24E7 -0.73 -0.9782 -0.9982 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B06 compound treatment 5.39757984E8 8020000.0 0.12 5.42590159E8 -2.32E7 -0.52 -0.2821 -0.5237 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B07 compound treatment 4.78428789E8 -5.33E7 -0.83 5.25277707E8 -4.05E7 -0.92 -1.2342 -0.9988 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B08 compound treatment 5.44166014E8 1.24E7 0.19 5.65424502E8 -347000.0 -0.01 0.1314 0.678 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B09 compound treatment 5.13403551E8 -1.83E7 -0.29 5.16613648E8 -4.92E7 -1.11 -0.9875 -0.8609 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B10 compound treatment 5.00612087E8 -3.11E7 -0.48 5.37682688E8 -2.81E7 -0.63 -0.7916 -0.9911 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B11 compound treatment 4.66280219E8 -6.55E7 -1.02 5.62533463E8 -3240000.0 -0.07 -0.7726 -0.7559 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B12 compound treatment 4.86596866E8 -4.51E7 -0.7 5.49881812E8 -1.59E7 -0.36 -0.7511 -0.9514 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B13 mock treatment 5.07676489E8 -2.41E7 -0.37 5.83710297E8 1.79E7 0.41 0.0217 0.0393 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B14 mock treatment 5.01650146E8 -3.01E7 -0.47 5.69387598E8 3620000.0 0.08 -0.2735 -0.5751 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B15 compound treatment 4.77099794E8 -5.46E7 -0.85 5.22353941E8 -4.34E7 -0.98 -1.2956 -0.9975 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B16 compound treatment 5.09452491E8 -2.23E7 -0.35 5.40094946E8 -2.57E7 -0.58 -0.6557 -0.9698 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B17 compound treatment 4.94580682E8 -3.72E7 -0.58 5.28991439E8 -3.68E7 -0.83 -0.997 -0.9843 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B18 compound treatment 4.86146572E8 -4.56E7 -0.71 5.29681708E8 -3.61E7 -0.82 -1.0788 -0.9976 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B19 compound treatment 4.54303594E8 -7.74E7 -1.21 5.14832526E8 -5.09E7 -1.15 -1.6668 -0.9997 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B20 compound treatment 4.94300526E8 -3.74E7 -0.58 5.59823159E8 -5950000.0 -0.13 -0.5073 -0.8479 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B21 compound treatment 4.8507041E8 -4.67E7 -0.73 5.2798249E8 -3.78E7 -0.85 -1.1178 -0.9968 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B22 compound treatment 4.92031147E8 -3.97E7 -0.62 5.41588191E8 -2.42E7 -0.55 -0.8237 -0.9981 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B23 compound treatment 4.51615536E8 -8.01E7 -1.25 5.15011239E8 -5.08E7 -1.15 -1.6936 -0.9991 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 B24 compound treatment 4.94527618E8 -3.72E7 -0.58 5.4661062E8 -1.92E7 -0.43 -0.716 -0.9897 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C01 compound treatment 5.30996819E8 -737000.0 -0.01 5.6757733E8 1810000.0 0.04 0.0208 0.4894 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C02 compound treatment 5.6285911E8 3.11E7 0.48 5.70456614E8 4690000.0 0.11 0.4177 0.8417 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C03 compound treatment 5.4046387E8 8730000.0 0.14 5.54470863E8 -1.13E7 -0.26 -0.0844 -0.2918 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C04 compound treatment 5.48954023E8 1.72E7 0.27 5.714022E8 5630000.0 0.13 0.2797 0.942 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C05 compound treatment 5.53281146E8 2.15E7 0.34 5.94852417E8 2.91E7 0.66 0.7021 0.9513 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C06 compound treatment 5.44306354E8 1.26E7 0.2 5.74700441E8 8930000.0 0.2 0.2812 0.9999 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C07 compound treatment 5.38158275E8 6420000.0 0.1 6.08229422E8 4.25E7 0.96 0.7493 0.7766 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C08 compound treatment 5.61788363E8 3.01E7 0.47 5.79242199E8 1.35E7 0.3 0.5463 0.9783 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C09 compound treatment 5.13396845E8 -1.83E7 -0.29 5.24597936E8 -4.12E7 -0.93 -0.8599 -0.8835 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C10 compound treatment 5.48463312E8 1.67E7 0.26 5.60524983E8 -5250000.0 -0.12 0.1004 0.3508 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C11 mock treatment 5.45986579E8 1.43E7 0.22 5.75102721E8 9330000.0 0.21 0.3061 0.9997 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C12 mock treatment 5.46849454E8 1.51E7 0.24 6.04908431E8 3.91E7 0.88 0.7919 0.8652 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C13 compound treatment 5.11233785E8 -2.05E7 -0.32 5.49190445E8 -1.66E7 -0.37 -0.4908 -0.9968 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C14 compound treatment 5.61197783E8 2.95E7 0.46 5.70213922E8 4440000.0 0.1 0.3955 0.8419 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C15 mock treatment 5.62359501E8 3.06E7 0.48 5.93407493E8 2.76E7 0.62 0.779 0.9911 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C16 mock treatment 5.47902523E8 1.62E7 0.25 6.17581924E8 5.18E7 1.17 1.0061 0.84 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C17 compound treatment 5.37268633E8 5540000.0 0.09 5.41740568E8 -2.4E7 -0.54 -0.3231 -0.5875 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C18 compound treatment 5.43564412E8 1.18E7 0.18 5.54860923E8 -1.09E7 -0.25 -0.044 -0.1431 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C19 compound treatment 5.29160973E8 -2570000.0 -0.04 5.59823126E8 -5950000.0 -0.13 -0.1234 -0.8796 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C20 compound treatment 5.62768245E8 3.1E7 0.48 5.59093523E8 -6680000.0 -0.15 0.2351 0.4643 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C21 compound treatment 5.22745759E8 -8990000.0 -0.14 5.41495709E8 -2.43E7 -0.55 -0.4869 -0.86 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C22 compound treatment 5.25694063E8 -6040000.0 -0.09 5.71311623E8 5540000.0 0.13 0.022 0.1406 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C23 compound treatment 5.11937808E8 -1.98E7 -0.31 5.64434618E8 -1340000.0 -0.03 -0.2394 -0.7727 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 C24 compound treatment 5.16074967E8 -1.57E7 -0.24 5.6656721E8 796000.0 0.02 -0.1597 -0.6532 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D01 compound treatment 5.11742564E8 -2.0E7 -0.31 5.44598601E8 -2.12E7 -0.48 -0.5585 -0.9783 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D02 compound treatment 5.73611863E8 4.19E7 0.65 5.68035999E8 2260000.0 0.05 0.4974 0.7603 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D03 compound treatment 5.06748102E8 -2.5E7 -0.39 5.37277884E8 -2.85E7 -0.64 -0.7305 -0.9709 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D04 compound treatment 5.27459377E8 -4270000.0 -0.07 5.50624251E8 -1.51E7 -0.34 -0.2891 -0.8291 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D05 compound treatment 5.15346706E8 -1.64E7 -0.26 6.01502586E8 3.57E7 0.81 0.3905 0.4611 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D06 compound treatment 5.86874135E8 5.51E7 0.86 5.59775856E8 -6000000.0 -0.14 0.5115 0.5883 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D07 compound treatment 5.4589031E8 1.42E7 0.22 5.75394979E8 9620000.0 0.22 0.3097 1.0 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D08 compound treatment 5.83158404E8 5.14E7 0.8 6.125346E8 4.68E7 1.06 1.3137 0.9906 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D09 compound treatment 5.33936375E8 2200000.0 0.03 5.70898537E8 5130000.0 0.12 0.1062 0.8788 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D10 compound treatment 5.54118395E8 2.24E7 0.35 6.20025971E8 5.43E7 1.23 1.1136 0.8735 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D11 mock treatment 5.65968598E8 3.42E7 0.53 5.94524012E8 2.88E7 0.65 0.8366 0.9952 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D12 mock treatment 5.35000703E8 3270000.0 0.05 5.6282512E8 -2950000.0 -0.07 -0.0111 -0.1324 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D13 compound treatment 5.31453616E8 -280000.0 0.0 5.29333739E8 -3.64E7 -0.82 -0.5854 -0.7108 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D14 compound treatment 5.50461628E8 1.87E7 0.29 5.64593111E8 -1180000.0 -0.03 0.1874 0.6399 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D15 mock treatment 5.60973422E8 2.92E7 0.46 5.83569143E8 1.78E7 0.4 0.6065 0.9981 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D16 mock treatment 5.339987E8 2270000.0 0.04 5.94646327E8 2.89E7 0.65 0.4864 0.7443 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D17 compound treatment 5.10832791E8 -2.09E7 -0.33 5.25538913E8 -4.02E7 -0.91 -0.8731 -0.9041 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D18 compound treatment 5.7170125E8 4.0E7 0.62 5.68688567E8 2920000.0 0.07 0.4868 0.7776 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D19 compound treatment 5.18566433E8 -1.32E7 -0.21 5.66260052E8 489000.0 0.01 -0.1372 -0.668 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D20 compound treatment 5.5274818E8 2.1E7 0.33 5.97297955E8 3.15E7 0.71 0.7353 0.9377 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D21 compound treatment 5.4206145E8 1.03E7 0.16 5.55090931E8 -1.07E7 -0.24 -0.0569 -0.1962 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D22 compound treatment 5.51601197E8 1.99E7 0.31 5.51646E8 -1.41E7 -0.32 -0.0069 -0.0155 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D23 compound treatment 5.28591762E8 -3140000.0 -0.05 5.49806445E8 -1.6E7 -0.36 -0.2897 -0.7957 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 D24 compound treatment 5.33532164E8 1800000.0 0.03 5.78749217E8 1.3E7 0.29 0.2272 0.7711 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E01 mock treatment 5.08114058E8 -2.36E7 -0.37 5.60103345E8 -5670000.0 -0.13 -0.3507 -0.9003 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E02 mock treatment 5.15475348E8 -1.63E7 -0.25 5.26176034E8 -3.96E7 -0.89 -0.8118 -0.8729 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E03 compound treatment 5.13716916E8 -1.8E7 -0.28 5.1491634E8 -5.09E7 -1.15 -1.0111 -0.8547 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E04 compound treatment 4.93239056E8 -3.85E7 -0.6 5.65696668E8 -74400.0 0.0 -0.4252 -0.7091 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E05 compound treatment 5.3186046E8 127000.0 0.0 5.55633718E8 -1.01E7 -0.23 -0.1606 -0.701 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E06 compound treatment 5.08243069E8 -2.35E7 -0.37 5.45792072E8 -2.0E7 -0.45 -0.578 -0.9946 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E07 compound treatment 5.13767058E8 -1.8E7 -0.28 5.31757344E8 -3.4E7 -0.77 -0.7414 -0.9063 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E08 compound treatment 5.04368399E8 -2.74E7 -0.43 5.19456185E8 -4.63E7 -1.05 -1.0415 -0.9216 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E09 mock treatment 5.37317432E8 5580000.0 0.09 5.57117219E8 -8650000.0 -0.2 -0.0768 -0.3588 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E10 mock treatment 5.30810891E8 -923000.0 -0.01 5.65711548E8 -59500.0 0.0 -0.0111 -0.7699 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E11 compound treatment 5.07398002E8 -2.43E7 -0.38 5.44750476E8 -2.1E7 -0.48 -0.604 -0.9937 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E12 compound treatment 4.8492995E8 -4.68E7 -0.73 5.30762927E8 -3.5E7 -0.79 -1.0749 -0.9992 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E13 compound treatment 4.66808709E8 -6.49E7 -1.01 5.10294784E8 -5.55E7 -1.25 -1.6016 -0.9943 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E14 compound treatment 5.1077653E8 -2.1E7 -0.33 5.67868702E8 2100000.0 0.05 -0.1973 -0.5981 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E15 compound treatment 5.23911802E8 -7820000.0 -0.12 5.41393877E8 -2.44E7 -0.55 -0.4757 -0.8431 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E16 compound treatment 5.12662913E8 -1.91E7 -0.3 5.43772645E8 -2.2E7 -0.5 -0.5616 -0.9697 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E17 mock treatment 5.29184288E8 -2550000.0 -0.04 5.4856768E8 -1.72E7 -0.39 -0.303 -0.7753 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E18 mock treatment 5.26340028E8 -5390000.0 -0.08 5.26595595E8 -3.92E7 -0.89 -0.6855 -0.7707 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E19 compound treatment 5.21151498E8 -1.06E7 -0.16 5.16922155E8 -4.88E7 -1.1 -0.8972 -0.8038 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E20 compound treatment 5.2986744E8 -1870000.0 -0.03 5.51178973E8 -1.46E7 -0.33 -0.2537 -0.7665 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E21 compound treatment 5.13287719E8 -1.84E7 -0.29 5.47878847E8 -1.79E7 -0.4 -0.4891 -0.986 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E22 compound treatment 5.04971485E8 -2.68E7 -0.42 5.30779301E8 -3.5E7 -0.79 -0.8539 -0.9552 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E23 compound treatment 5.04977951E8 -2.68E7 -0.42 5.20881171E8 -4.49E7 -1.01 -1.0121 -0.9228 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 E24 compound treatment 5.04611088E8 -2.71E7 -0.42 5.36729022E8 -2.9E7 -0.66 -0.7628 -0.9773 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F01 mock treatment 5.30293642E8 -1440000.0 -0.02 5.63294677E8 -2480000.0 -0.06 -0.0554 -0.9194 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F02 mock treatment 5.25272795E8 -6460000.0 -0.1 5.75786812E8 1.0E7 0.23 0.0889 0.3589 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F03 compound treatment 5.39342395E8 7610000.0 0.12 5.33559739E8 -3.22E7 -0.73 -0.431 -0.5843 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F04 compound treatment 5.39981727E8 8250000.0 0.13 5.91132637E8 2.54E7 0.57 0.4961 0.8446 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F05 compound treatment 5.31046583E8 -687000.0 -0.01 5.36799019E8 -2.9E7 -0.65 -0.4706 -0.7186 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F06 compound treatment 5.7100585E8 3.93E7 0.61 5.77704524E8 1.19E7 0.27 0.6232 0.9323 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F07 compound treatment 5.70194701E8 3.85E7 0.6 6.052529E8 3.95E7 0.89 1.0546 0.9812 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F08 compound treatment 5.32063783E8 330000.0 0.01 5.98595272E8 3.28E7 0.74 0.5282 0.712 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F09 mock treatment 5.28381339E8 -3350000.0 -0.05 5.901409E8 2.44E7 0.55 0.3525 0.6372 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F10 mock treatment 5.26118551E8 -5610000.0 -0.09 5.72629807E8 6860000.0 0.16 0.0478 0.2684 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F11 compound treatment 5.36718618E8 4990000.0 0.08 5.3671193E8 -2.91E7 -0.66 -0.4095 -0.6192 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F12 compound treatment 5.2149899E8 -1.02E7 -0.16 5.72932981E8 7160000.0 0.16 0.0017 0.0076 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F13 compound treatment 5.13167774E8 -1.86E7 -0.29 5.30307109E8 -3.55E7 -0.8 -0.7712 -0.9051 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F14 compound treatment 5.32704672E8 971000.0 0.02 5.78766742E8 1.3E7 0.29 0.2184 0.7425 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F15 compound treatment 5.31693462E8 -40000.0 0.0 5.62713382E8 -3060000.0 -0.07 -0.0493 -0.7135 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F16 compound treatment 5.3976285E8 8030000.0 0.13 5.61213394E8 -4560000.0 -0.1 0.0156 0.0963 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F17 mock treatment 5.2799649E8 -3740000.0 -0.06 5.53895163E8 -1.19E7 -0.27 -0.2309 -0.8409 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F18 mock treatment 5.31111254E8 -622000.0 -0.01 5.52407594E8 -1.34E7 -0.3 -0.2204 -0.7294 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F19 compound treatment 5.13184001E8 -1.85E7 -0.29 5.71971829E8 6200000.0 0.14 -0.1052 -0.3276 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F20 compound treatment 5.42691575E8 1.1E7 0.17 5.6026325E8 -5510000.0 -0.12 0.0327 0.1547 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F21 compound treatment 5.15447018E8 -1.63E7 -0.25 5.62747601E8 -3020000.0 -0.07 -0.2277 -0.8667 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F22 compound treatment 5.26354556E8 -5380000.0 -0.08 5.38558434E8 -2.72E7 -0.62 -0.4941 -0.7961 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F23 compound treatment 5.14910836E8 -1.68E7 -0.26 5.52839939E8 -1.29E7 -0.29 -0.3919 -0.9985 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 F24 compound treatment 5.04073863E8 -2.77E7 -0.43 5.66996633E8 1230000.0 0.03 -0.2851 -0.6603 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G01 compound treatment 5.5126761E8 1.95E7 0.3 5.97145167E8 3.14E7 0.71 0.7165 0.9286 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G02 compound treatment 5.02322488E8 -2.94E7 -0.46 5.34620164E8 -3.12E7 -0.7 -0.8217 -0.9783 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G03 mock treatment 5.64981989E8 3.32E7 0.52 5.58651499E8 -7120000.0 -0.16 0.2524 0.4655 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G04 mock treatment 5.45020998E8 1.33E7 0.21 5.78614975E8 1.28E7 0.29 0.3516 0.9863 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G05 compound treatment 5.79447587E8 4.77E7 0.74 5.80408489E8 1.46E7 0.33 0.7594 0.9335 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G06 compound treatment 5.30457321E8 -1280000.0 -0.02 5.57380757E8 -8390000.0 -0.19 -0.1481 -0.777 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G07 compound treatment 5.68609711E8 3.69E7 0.57 5.53128977E8 -1.26E7 -0.29 0.2041 0.3182 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G08 compound treatment 5.37384395E8 5650000.0 0.09 5.85965537E8 2.02E7 0.46 0.385 0.8282 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G09 compound treatment 5.76420754E8 4.47E7 0.7 5.91567914E8 2.58E7 0.58 0.9044 0.9961 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G10 compound treatment 5.27855552E8 -3880000.0 -0.06 5.8237891E8 1.66E7 0.38 0.2227 0.5858 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G11 compound treatment 5.54080702E8 2.23E7 0.35 5.6469729E8 -1070000.0 -0.02 0.229 0.6562 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G12 compound treatment 5.26473519E8 -5260000.0 -0.08 5.63932813E8 -1840000.0 -0.04 -0.0873 -0.9505 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G13 compound treatment 5.349054E8 3170000.0 0.05 5.46646565E8 -1.91E7 -0.43 -0.2707 -0.6222 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G14 compound treatment 5.41840811E8 1.01E7 0.16 5.60159719E8 -5610000.0 -0.13 0.0216 0.1071 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G15 compound treatment 5.47343431E8 1.56E7 0.24 5.69794058E8 4020000.0 0.09 0.2362 0.91 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G16 compound treatment 5.38407894E8 6670000.0 0.1 5.60813569E8 -4960000.0 -0.11 -0.0057 -0.0374 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G17 compound treatment 5.5189715E8 2.02E7 0.31 5.90933763E8 2.52E7 0.57 0.6242 0.9608 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G18 compound treatment 5.2567081E8 -6060000.0 -0.09 5.58147168E8 -7620000.0 -0.17 -0.1886 -0.9599 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G19 mock treatment 5.59457471E8 2.77E7 0.43 5.69596475E8 3830000.0 0.09 0.3665 0.8322 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G20 mock treatment 5.48518598E8 1.68E7 0.26 5.77690422E8 1.19E7 0.27 0.3753 0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G21 compound treatment 5.40952568E8 9220000.0 0.14 5.7653476E8 1.08E7 0.24 0.2735 0.9684 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G22 compound treatment 5.24695572E8 -7040000.0 -0.11 5.58879073E8 -6890000.0 -0.16 -0.1877 -0.9852 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G23 compound treatment 5.20012575E8 -1.17E7 -0.18 5.61246006E8 -4530000.0 -0.1 -0.2014 -0.9625 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 G24 compound treatment 5.29206806E8 -2530000.0 -0.04 5.70586408E8 4820000.0 0.11 0.0491 0.4245 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H01 compound treatment 5.341556E8 2420000.0 0.04 5.87678193E8 2.19E7 0.5 0.3768 0.7588 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H02 compound treatment 5.54640166E8 2.29E7 0.36 6.03868287E8 3.81E7 0.86 0.8611 0.9239 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H03 mock treatment 5.81803684E8 5.01E7 0.78 5.94879456E8 2.91E7 0.66 1.0166 0.9964 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H04 mock treatment 5.91978736E8 6.02E7 0.94 6.07565541E8 4.18E7 0.94 1.3314 1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H05 compound treatment 5.56078494E8 2.43E7 0.38 6.03608704E8 3.78E7 0.86 0.8728 0.933 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H06 compound treatment 5.5167151E8 1.99E7 0.31 5.66757566E8 987000.0 0.02 0.2354 0.7559 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H07 compound treatment 5.53889131E8 2.22E7 0.35 5.64096539E8 -1670000.0 -0.04 0.2173 0.6258 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H08 compound treatment 5.7451506E8 4.28E7 0.67 5.86336166E8 2.06E7 0.46 0.7998 0.9845 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H09 compound treatment 5.59105833E8 2.74E7 0.43 5.50297273E8 -1.55E7 -0.35 0.0542 0.0983 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H10 compound treatment 5.66855121E8 3.51E7 0.55 5.93381715E8 2.76E7 0.62 0.8281 0.9978 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H11 compound treatment 5.64377347E8 3.26E7 0.51 5.9505626E8 2.93E7 0.66 0.8275 0.9915 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H12 compound treatment 5.64137453E8 3.24E7 0.5 5.68133054E8 2360000.0 0.05 0.3946 0.7776 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H13 compound treatment 5.48600689E8 1.69E7 0.26 5.75870767E8 1.01E7 0.23 0.3472 0.9975 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H14 compound treatment 5.64227051E8 3.25E7 0.51 6.2483903E8 5.91E7 1.33 1.3018 0.9119 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H15 compound treatment 5.4802005E8 1.63E7 0.25 5.86270189E8 2.05E7 0.46 0.507 0.9598 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H16 compound treatment 5.7307882E8 4.13E7 0.64 6.24118691E8 5.83E7 1.32 1.3878 0.9457 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H17 compound treatment 5.36980597E8 5250000.0 0.08 5.65472546E8 -299000.0 -0.01 0.053 0.6465 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H18 compound treatment 5.57777148E8 2.6E7 0.41 5.9995704E8 3.42E7 0.77 0.8332 0.9548 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H19 mock treatment 5.56127761E8 2.44E7 0.38 5.99424281E8 3.37E7 0.76 0.8065 0.9486 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H20 mock treatment 5.73996182E8 4.23E7 0.66 5.72566679E8 6800000.0 0.15 0.5741 0.8493 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H21 compound treatment 5.42248084E8 1.05E7 0.16 5.78168152E8 1.24E7 0.28 0.3139 0.9673 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H22 compound treatment 5.71136754E8 3.94E7 0.61 5.98091669E8 3.23E7 0.73 0.9505 0.9963 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H23 compound treatment 5.32582623E8 849000.0 0.01 5.76026571E8 1.03E7 0.23 0.1732 0.7462 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 H24 compound treatment 5.56932339E8 2.52E7 0.39 5.56063926E8 -9710000.0 -0.22 0.1224 0.2722 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I01 compound treatment 4.96432679E8 -3.53E7 -0.55 5.02847955E8 -6.29E7 -1.42 -1.3944 -0.9145 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I02 compound treatment 4.39071088E8 -9.27E7 -1.44 4.61149907E8 -1.05E8 -2.36 -2.6925 -0.972 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I03 compound treatment 4.75460832E8 -5.63E7 -0.88 4.95797937E8 -7.0E7 -1.58 -1.738 -0.9613 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I04 compound treatment 4.84818402E8 -4.69E7 -0.73 5.00057313E8 -6.57E7 -1.49 -1.5669 -0.9466 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I05 mock treatment 5.57066176E8 2.53E7 0.39 5.23652119E8 -4.21E7 -0.95 -0.3941 -0.3824 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I06 mock treatment 4.86270053E8 -4.55E7 -0.71 5.37466587E8 -2.83E7 -0.64 -0.9531 -0.9987 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I07 compound treatment 4.90428948E8 -4.13E7 -0.64 5.28230105E8 -3.75E7 -0.85 -1.0549 -0.9907 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I08 compound treatment 4.67544629E8 -6.42E7 -1.0 5.51127447E8 -1.46E7 -0.33 -0.941 -0.8935 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I09 compound treatment 4.86754182E8 -4.5E7 -0.7 5.55606049E8 -1.02E7 -0.23 -0.6578 -0.8922 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I10 compound treatment 4.46012816E8 -8.57E7 -1.34 5.09283544E8 -5.65E7 -1.28 -1.8468 -0.9997 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I11 compound treatment 4.77990131E8 -5.37E7 -0.84 5.19730238E8 -4.6E7 -1.04 -1.3277 -0.9942 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I12 compound treatment 4.47769492E8 -8.4E7 -1.31 5.27982267E8 -3.78E7 -0.85 -1.5287 -0.9787 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I13 compound treatment 4.97686676E8 -3.4E7 -0.53 5.10811246E8 -5.5E7 -1.24 -1.2533 -0.928 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I14 compound treatment 4.59175808E8 -7.26E7 -1.13 5.10215418E8 -5.56E7 -1.26 -1.687 -0.9986 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I15 compound treatment 4.95527952E8 -3.62E7 -0.56 5.42305293E8 -2.35E7 -0.53 -0.7738 -0.9995 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I16 compound treatment 4.94742018E8 -3.7E7 -0.58 5.29828431E8 -3.59E7 -0.81 -0.9818 -0.9858 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I17 compound treatment 4.5493017E8 -7.68E7 -1.2 5.24652144E8 -4.11E7 -0.93 -1.503 -0.9922 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I18 compound treatment 4.52021337E8 -7.97E7 -1.24 5.24334133E8 -4.14E7 -0.94 -1.5401 -0.9903 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I19 compound treatment 4.61293006E8 -7.04E7 -1.1 5.32006584E8 -3.38E7 -0.76 -1.3154 -0.9843 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I20 compound treatment 4.48890387E8 -8.28E7 -1.29 5.2130276E8 -4.45E7 -1.0 -1.6231 -0.9924 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I21 mock treatment 4.9862779E8 -3.31E7 -0.52 5.46730202E8 -1.9E7 -0.43 -0.6689 -0.996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I22 mock treatment 4.64784443E8 -6.69E7 -1.04 5.36830462E8 -2.89E7 -0.65 -1.1999 -0.9747 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I23 compound treatment 4.55426587E8 -7.63E7 -1.19 5.27168187E8 -3.86E7 -0.87 -1.4573 -0.9884 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 I24 compound treatment 4.21827966E8 -1.1E8 -1.71 4.98051437E8 -6.77E7 -1.53 -2.2927 -0.9984 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J01 compound treatment 4.57752487E8 -7.4E7 -1.15 5.2394954E8 -4.18E7 -0.95 -1.4832 -0.9952 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J02 compound treatment 5.10293892E8 -2.14E7 -0.33 5.36742032E8 -2.9E7 -0.66 -0.7 -0.9509 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J03 compound treatment 4.57819438E8 -7.39E7 -1.15 5.30642552E8 -3.51E7 -0.79 -1.3755 -0.9835 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J04 compound treatment 4.83394534E8 -4.83E7 -0.75 5.6246174E8 -3310000.0 -0.07 -0.5853 -0.7735 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J05 mock treatment 5.09696502E8 -2.2E7 -0.34 5.44322475E8 -2.14E7 -0.48 -0.5855 -0.9857 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J06 mock treatment 5.39893283E8 8160000.0 0.13 5.3549574E8 -3.03E7 -0.68 -0.3939 -0.5661 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J07 compound treatment 5.11024595E8 -2.07E7 -0.32 5.36501391E8 -2.93E7 -0.66 -0.6958 -0.9455 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J08 compound treatment 5.41465686E8 9730000.0 0.15 5.83787023E8 1.8E7 0.41 0.3951 0.9094 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J09 compound treatment 4.70111654E8 -6.16E7 -0.96 4.97329378E8 -6.84E7 -1.55 -1.7724 -0.9737 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J10 compound treatment 5.15592537E8 -1.61E7 -0.25 5.35535899E8 -3.02E7 -0.68 -0.661 -0.9078 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J11 compound treatment 4.73315673E8 -5.84E7 -0.91 5.11218013E8 -5.46E7 -1.23 -1.5152 -0.9888 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J12 compound treatment 4.44953191E8 -8.68E7 -1.35 5.67087364E8 1320000.0 0.03 -0.9348 -0.6914 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J13 compound treatment 4.9241368E8 -3.93E7 -0.61 5.33903106E8 -3.19E7 -0.72 -0.9423 -0.9967 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J14 compound treatment 4.77614483E8 -5.41E7 -0.84 5.27392149E8 -3.84E7 -0.87 -1.2094 -0.9999 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J15 compound treatment 5.08323852E8 -2.34E7 -0.36 5.45198558E8 -2.06E7 -0.46 -0.5866 -0.9928 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J16 compound treatment 5.17658125E8 -1.41E7 -0.22 5.39760522E8 -2.6E7 -0.59 -0.5707 -0.9096 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J17 compound treatment 4.55638672E8 -7.61E7 -1.19 5.49921422E8 -1.58E7 -0.36 -1.0914 -0.8814 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J18 compound treatment 5.0038595E8 -3.13E7 -0.49 5.66008746E8 238000.0 0.01 -0.3415 -0.6993 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J19 compound treatment 4.70025346E8 -6.17E7 -0.96 5.14556728E8 -5.12E7 -1.16 -1.4981 -0.9957 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J20 compound treatment 4.9353096E8 -3.82E7 -0.6 5.50907326E8 -1.49E7 -0.34 -0.6583 -0.9634 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J21 mock treatment 4.92721142E8 -3.9E7 -0.61 5.43305699E8 -2.25E7 -0.51 -0.7887 -0.996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J22 mock treatment 4.84744244E8 -4.7E7 -0.73 5.50145949E8 -1.56E7 -0.35 -0.7672 -0.9441 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J23 compound treatment 4.81926554E8 -4.98E7 -0.78 5.46515813E8 -1.93E7 -0.44 -0.8563 -0.9626 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 J24 compound treatment 4.6678011E8 -6.5E7 -1.01 5.21848393E8 -4.39E7 -0.99 -1.4173 -1.0 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K01 compound treatment 4.75994009E8 -5.57E7 -0.87 4.78091047E8 -8.77E7 -1.98 -2.0151 -0.9314 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K02 compound treatment 4.57569861E8 -7.42E7 -1.16 4.62956806E8 -1.03E8 -2.32 -2.4599 -0.948 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K03 compound treatment 4.91937465E8 -3.98E7 -0.62 4.82606375E8 -8.32E7 -1.88 -1.7673 -0.893 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K04 compound treatment 4.95184104E8 -3.65E7 -0.57 4.79557897E8 -8.62E7 -1.95 -1.7803 -0.877 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K05 compound treatment 4.93548752E8 -3.82E7 -0.59 5.11259025E8 -5.45E7 -1.23 -1.2917 -0.9442 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K06 compound treatment 4.73321831E8 -5.84E7 -0.91 4.60726788E8 -1.05E8 -2.37 -2.322 -0.9133 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K07 mock treatment 4.95650486E8 -3.61E7 -0.56 5.47624254E8 -1.81E7 -0.41 -0.6874 -0.988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K08 mock treatment 5.23679948E8 -8050000.0 -0.13 5.66042224E8 271000.0 0.01 -0.0844 -0.6718 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K09 compound treatment 4.80382162E8 -5.14E7 -0.8 4.75177531E8 -9.06E7 -2.05 -2.0133 -0.9159 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K10 compound treatment 4.68911152E8 -6.28E7 -0.98 4.92320595E8 -7.35E7 -1.66 -1.8657 -0.9682 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K11 compound treatment 4.72928069E8 -5.88E7 -0.92 4.82273428E8 -8.35E7 -1.89 -1.982 -0.9449 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K12 compound treatment 4.95901623E8 -3.58E7 -0.56 4.69412503E8 -9.64E7 -2.18 -1.9345 -0.8605 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K13 compound treatment 4.86377665E8 -4.54E7 -0.71 4.81691158E8 -8.41E7 -1.9 -1.8432 -0.9092 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K14 compound treatment 4.65310582E8 -6.64E7 -1.03 4.70069846E8 -9.57E7 -2.16 -2.2609 -0.943 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K15 mock treatment 5.19495786E8 -1.22E7 -0.19 5.34186915E8 -3.16E7 -0.71 -0.6395 -0.8656 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K16 mock treatment 4.82954242E8 -4.88E7 -0.76 5.31288586E8 -3.45E7 -0.78 -1.0883 -0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K17 compound treatment 4.67823168E8 -6.39E7 -1.0 4.82788281E8 -8.3E7 -1.88 -2.03 -0.9561 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K18 compound treatment 4.61849179E8 -6.99E7 -1.09 4.90329021E8 -7.54E7 -1.7 -1.9753 -0.9765 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K19 compound treatment 4.56603101E8 -7.51E7 -1.17 5.00450418E8 -6.53E7 -1.48 -1.8713 -0.9934 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K20 compound treatment 4.61027043E8 -7.07E7 -1.1 4.82943396E8 -8.28E7 -1.87 -2.1024 -0.968 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K21 compound treatment 4.73709788E8 -5.8E7 -0.9 5.05616434E8 -6.02E7 -1.36 -1.6004 -0.9803 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K22 compound treatment 4.42019422E8 -8.97E7 -1.4 5.04498958E8 -6.13E7 -1.38 -1.9673 -1.0 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K23 mock treatment 5.03250082E8 -2.85E7 -0.44 5.18273825E8 -4.75E7 -1.07 -1.0727 -0.9236 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 K24 mock treatment 4.82011216E8 -4.97E7 -0.77 5.04375663E8 -6.14E7 -1.39 -1.5288 -0.9621 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L01 compound treatment 5.46101995E8 1.44E7 0.22 5.01036187E8 -6.47E7 -1.46 -0.8763 -0.592 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L02 compound treatment 5.24684177E8 -7050000.0 -0.11 5.71932085E8 6160000.0 0.14 0.0208 0.1174 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L03 compound treatment 5.43491807E8 1.18E7 0.18 5.56017484E8 -9750000.0 -0.22 -0.0264 -0.092 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L04 compound treatment 5.52710889E8 2.1E7 0.33 5.24814248E8 -4.1E7 -0.93 -0.4235 -0.4314 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L05 compound treatment 5.09124471E8 -2.26E7 -0.35 5.51552313E8 -1.42E7 -0.32 -0.4762 -0.999 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L06 compound treatment 5.17931876E8 -1.38E7 -0.21 5.47723487E8 -1.8E7 -0.41 -0.4404 -0.9552 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L07 mock treatment 5.02853201E8 -2.89E7 -0.45 5.35260398E8 -3.05E7 -0.69 -0.8057 -0.9786 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L08 mock treatment 5.35155498E8 3420000.0 0.05 5.79517947E8 1.37E7 0.31 0.2574 0.8165 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L09 compound treatment 5.11455291E8 -2.03E7 -0.32 5.20181067E8 -4.56E7 -1.03 -0.9519 -0.8833 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L10 compound treatment 5.1581434E8 -1.59E7 -0.25 5.30591773E8 -3.52E7 -0.8 -0.7375 -0.8856 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L11 compound treatment 4.80948485E8 -5.08E7 -0.79 5.39340821E8 -2.64E7 -0.6 -0.9817 -0.9904 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L12 compound treatment 4.73905597E8 -5.78E7 -0.9 5.2182263E8 -4.39E7 -0.99 -1.3392 -0.9988 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L13 compound treatment 5.05237066E8 -2.65E7 -0.41 5.10974451E8 -5.48E7 -1.24 -1.1675 -0.8944 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L14 compound treatment 5.1408747E8 -1.76E7 -0.27 5.20291335E8 -4.55E7 -1.03 -0.9211 -0.8658 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L15 mock treatment 5.33117001E8 1380000.0 0.02 5.50140899E8 -1.56E7 -0.35 -0.2345 -0.6627 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L16 mock treatment 5.53985647E8 2.23E7 0.35 5.43704306E8 -2.21E7 -0.5 -0.1076 -0.1771 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L17 compound treatment 4.93506442E8 -3.82E7 -0.6 5.17857222E8 -4.79E7 -1.08 -1.1867 -0.9603 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L18 compound treatment 5.12469595E8 -1.93E7 -0.3 5.43344953E8 -2.24E7 -0.51 -0.5706 -0.9687 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L19 compound treatment 4.89979729E8 -4.18E7 -0.65 5.20662495E8 -4.51E7 -1.02 -1.1807 -0.9764 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L20 compound treatment 4.90185699E8 -4.15E7 -0.65 5.18771414E8 -4.7E7 -1.06 -1.2087 -0.9718 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L21 compound treatment 3.67522385E8 -1.64E8 -2.56 5.17183234E8 -4.86E7 -1.1 -2.5851 -0.9287 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L22 compound treatment 5.08147818E8 -2.36E7 -0.37 5.48669694E8 -1.71E7 -0.39 -0.5331 -0.9997 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L23 mock treatment 5.10795279E8 -2.09E7 -0.33 5.63871419E8 -1900000.0 -0.04 -0.261 -0.7933 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 L24 mock treatment 5.09530557E8 -2.22E7 -0.35 5.40556294E8 -2.52E7 -0.57 -0.6475 -0.9714 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M01 compound treatment 4.88186223E8 -4.35E7 -0.68 5.39399424E8 -2.64E7 -0.6 -0.9011 -0.9979 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M02 compound treatment 4.8567399E8 -4.61E7 -0.72 5.68226085E8 2460000.0 0.06 -0.4681 -0.6505 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M03 compound treatment 5.08799155E8 -2.29E7 -0.36 5.44205734E8 -2.16E7 -0.49 -0.5972 -0.9883 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M04 compound treatment 5.03789857E8 -2.79E7 -0.44 5.5361895E8 -1.22E7 -0.27 -0.502 -0.9753 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M05 compound treatment 5.11535337E8 -2.02E7 -0.31 5.77557563E8 1.18E7 0.27 -0.0341 -0.0827 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M06 compound treatment 5.07305128E8 -2.44E7 -0.38 5.68915729E8 3140000.0 0.07 -0.2188 -0.5653 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M07 compound treatment 5.02010578E8 -2.97E7 -0.46 5.76528952E8 1.08E7 0.24 -0.1554 -0.2973 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M08 compound treatment 5.04460179E8 -2.73E7 -0.42 5.53814669E8 -1.2E7 -0.27 -0.4915 -0.9761 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M09 mock treatment 5.31968076E8 235000.0 0.0 5.89056844E8 2.33E7 0.53 0.3747 0.712 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M10 mock treatment 5.4196203E8 1.02E7 0.16 5.91474247E8 2.57E7 0.58 0.5234 0.869 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M11 compound treatment 5.28935316E8 -2800000.0 -0.04 5.3204165E8 -3.37E7 -0.76 -0.5698 -0.7463 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M12 compound treatment 5.00182675E8 -3.16E7 -0.49 5.49480663E8 -1.63E7 -0.37 -0.6078 -0.9899 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M13 mock treatment 5.39996289E8 8260000.0 0.13 5.53261628E8 -1.25E7 -0.28 -0.1089 -0.3506 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M14 mock treatment 5.21568959E8 -1.02E7 -0.16 5.43029751E8 -2.27E7 -0.51 -0.4754 -0.8839 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M15 compound treatment 5.07901225E8 -2.38E7 -0.37 5.4120924E8 -2.46E7 -0.56 -0.655 -0.9809 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M16 compound treatment 5.23349094E8 -8380000.0 -0.13 5.47090696E8 -1.87E7 -0.42 -0.3909 -0.8845 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M17 compound treatment 5.13451765E8 -1.83E7 -0.28 5.24455131E8 -4.13E7 -0.93 -0.8616 -0.8826 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M18 compound treatment 5.17273449E8 -1.45E7 -0.23 5.40685329E8 -2.51E7 -0.57 -0.5601 -0.9182 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M19 compound treatment 4.98326507E8 -3.34E7 -0.52 5.47013456E8 -1.88E7 -0.42 -0.6677 -0.9948 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M20 compound treatment 5.05328159E8 -2.64E7 -0.41 5.35605792E8 -3.02E7 -0.68 -0.7729 -0.9707 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M21 compound treatment 5.13285646E8 -1.84E7 -0.29 5.468658E8 -1.89E7 -0.43 -0.5053 -0.9814 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M22 compound treatment 5.28618903E8 -3110000.0 -0.05 5.19251646E8 -4.65E7 -1.05 -0.7777 -0.7389 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M23 compound treatment 5.05174144E8 -2.66E7 -0.41 5.05221401E8 -6.05E7 -1.37 -1.2601 -0.8815 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 M24 compound treatment 5.0688248E8 -2.49E7 -0.39 5.34878114E8 -3.09E7 -0.7 -0.7674 -0.9613 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N01 compound treatment 5.08984492E8 -2.27E7 -0.35 5.71518004E8 5750000.0 0.13 -0.1587 -0.4206 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N02 compound treatment 5.60451825E8 2.87E7 0.45 5.83761247E8 1.8E7 0.41 0.6038 0.9989 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N03 compound treatment 5.5064321E8 1.89E7 0.29 5.2794911E8 -3.78E7 -0.85 -0.3961 -0.4382 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N04 compound treatment 5.90010635E8 5.83E7 0.91 5.775294E8 1.18E7 0.27 0.8298 0.8773 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N05 compound treatment 5.83125199E8 5.14E7 0.8 5.60585417E8 -5190000.0 -0.12 0.4832 0.5972 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N06 compound treatment 5.52378643E8 2.06E7 0.32 6.20418038E8 5.46E7 1.24 1.1007 0.8625 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N07 compound treatment 5.49905436E8 1.82E7 0.28 5.46787597E8 -1.9E7 -0.43 -0.1032 -0.2008 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N08 compound treatment 5.32737741E8 1000000.0 0.02 5.80117086E8 1.43E7 0.32 0.2403 0.7404 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N09 mock treatment 5.36481533E8 4750000.0 0.07 5.93540484E8 2.78E7 0.63 0.4961 0.785 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N10 mock treatment 5.59146484E8 2.74E7 0.43 5.61774052E8 -4000000.0 -0.09 0.238 0.5454 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N11 compound treatment 5.24328946E8 -7400000.0 -0.12 5.54131423E8 -1.16E7 -0.26 -0.2676 -0.9315 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N12 compound treatment 5.33151832E8 1420000.0 0.02 5.70006201E8 4240000.0 0.1 0.0833 0.848 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N13 mock treatment 5.59347779E8 2.76E7 0.43 5.96146292E8 3.04E7 0.69 0.7896 0.9746 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N14 mock treatment 5.53530887E8 2.18E7 0.34 5.73678974E8 7910000.0 0.18 0.3664 0.9551 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N15 compound treatment 5.44594073E8 1.29E7 0.2 5.69753597E8 3980000.0 0.09 0.2053 0.9348 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N16 compound treatment 5.45829369E8 1.41E7 0.22 5.84332771E8 1.86E7 0.42 0.4519 0.9544 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N17 compound treatment 5.60346736E8 2.86E7 0.45 5.61508385E8 -4260000.0 -0.1 0.247 0.5417 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N18 compound treatment 5.44074626E8 1.23E7 0.19 5.55327094E8 -1.04E7 -0.24 -0.031 -0.1018 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N19 compound treatment 5.40619053E8 8890000.0 0.14 5.35277361E8 -3.05E7 -0.69 -0.3894 -0.554 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N20 compound treatment 5.49942317E8 1.82E7 0.28 5.88879765E8 2.31E7 0.52 0.5698 0.9588 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N21 compound treatment 5.11878817E8 -1.99E7 -0.31 5.45553762E8 -2.02E7 -0.46 -0.5418 -0.9819 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N22 compound treatment 5.36928872E8 5200000.0 0.08 5.74847015E8 9080000.0 0.21 0.2023 0.9173 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N23 compound treatment 5.19229832E8 -1.25E7 -0.19 5.17611498E8 -4.82E7 -1.09 -0.9073 -0.8206 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 N24 compound treatment 5.23949598E8 -7780000.0 -0.12 5.39619392E8 -2.62E7 -0.59 -0.5037 -0.8348 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O01 compound treatment 5.10158951E8 -2.16E7 -0.34 5.433247E8 -2.24E7 -0.51 -0.5963 -0.98 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O02 compound treatment 5.06784794E8 -2.49E7 -0.39 5.56672982E8 -9100000.0 -0.21 -0.4202 -0.9557 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O03 compound treatment 5.09013374E8 -2.27E7 -0.35 5.74161881E8 8390000.0 0.19 -0.1161 -0.2893 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O04 compound treatment 5.20553352E8 -1.12E7 -0.17 5.86104296E8 2.03E7 0.46 0.2018 0.4106 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O05 compound treatment 5.33444142E8 1710000.0 0.03 5.51305843E8 -1.45E7 -0.33 -0.2123 -0.6473 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O06 compound treatment 5.32260966E8 527000.0 0.01 5.67756159E8 1990000.0 0.04 0.0375 0.8229 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O07 compound treatment 5.33895384E8 2160000.0 0.03 5.50972137E8 -1.48E7 -0.33 -0.2127 -0.6327 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O08 compound treatment 5.63924367E8 3.22E7 0.5 5.46150938E8 -1.96E7 -0.44 0.041 0.0613 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O09 compound treatment 5.19629457E8 -1.21E7 -0.19 5.65887639E8 117000.0 0.0 -0.1314 -0.6972 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O10 compound treatment 5.48167112E8 1.64E7 0.26 5.51557101E8 -1.42E7 -0.32 -0.0462 -0.1124 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O11 mock treatment 5.35828503E8 4100000.0 0.06 5.94225856E8 2.85E7 0.64 0.4998 0.7734 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O12 mock treatment 5.54762913E8 2.3E7 0.36 6.01373497E8 3.56E7 0.8 0.8226 0.9338 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O13 compound treatment 5.29940075E8 -1790000.0 -0.03 5.41782397E8 -2.4E7 -0.54 -0.4031 -0.7426 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O14 compound treatment 5.2359756E8 -8140000.0 -0.13 5.76661321E8 1.09E7 0.25 0.0844 0.305 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O15 compound treatment 5.02544348E8 -2.92E7 -0.45 5.40740326E8 -2.5E7 -0.57 -0.7215 -0.9941 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O16 compound treatment 5.24135854E8 -7600000.0 -0.12 5.54565686E8 -1.12E7 -0.25 -0.2627 -0.94 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O17 compound treatment 5.13713107E8 -1.8E7 -0.28 5.626368E8 -3130000.0 -0.07 -0.2486 -0.8586 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O18 compound treatment 5.21703898E8 -1.0E7 -0.16 5.64918112E8 -853000.0 -0.02 -0.1241 -0.7884 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O19 compound treatment 5.19406362E8 -1.23E7 -0.19 5.4779863E8 -1.8E7 -0.41 -0.423 -0.9415 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O20 compound treatment 5.21934758E8 -9800000.0 -0.15 5.4690364E8 -1.89E7 -0.43 -0.4094 -0.904 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O21 compound treatment 5.00932567E8 -3.08E7 -0.48 5.4276421E8 -2.3E7 -0.52 -0.7069 -0.9992 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O22 compound treatment 5.26015796E8 -5720000.0 -0.09 5.3711969E8 -2.87E7 -0.65 -0.5208 -0.7969 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O23 compound treatment 5.01896206E8 -2.98E7 -0.46 5.13826875E8 -5.19E7 -1.17 -1.1587 -0.9177 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 O24 compound treatment 5.08071939E8 -2.37E7 -0.37 5.42666089E8 -2.31E7 -0.52 -0.6298 -0.9855 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P01 compound treatment 5.29300815E8 -2430000.0 -0.04 5.46048878E8 -1.97E7 -0.45 -0.342 -0.7645 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P02 compound treatment 5.37866547E8 6130000.0 0.1 5.47801275E8 -1.8E7 -0.41 -0.2196 -0.5264 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P03 compound treatment 4.99230907E8 -3.25E7 -0.51 5.54506822E8 -1.13E7 -0.25 -0.538 -0.9494 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P04 compound treatment 5.0794567E8 -2.38E7 -0.37 5.53013068E8 -1.28E7 -0.29 -0.4659 -0.9923 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P05 compound treatment 5.39864208E8 8130000.0 0.13 5.46840801E8 -1.89E7 -0.43 -0.213 -0.4773 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P06 compound treatment 5.57571038E8 2.58E7 0.4 5.48983017E8 -1.68E7 -0.38 0.0163 0.0294 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P07 compound treatment 5.48568759E8 1.68E7 0.26 5.53385519E8 -1.24E7 -0.28 -0.0125 -0.0326 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P08 compound treatment 5.54064294E8 2.23E7 0.35 5.6512999E8 -641000.0 -0.01 0.2357 0.6771 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P09 compound treatment 5.19668005E8 -1.21E7 -0.19 5.31465246E8 -3.43E7 -0.78 -0.6811 -0.8538 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P10 compound treatment 5.46104784E8 1.44E7 0.22 5.5561057E8 -1.02E7 -0.23 -0.0041 -0.0127 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P11 mock treatment 5.62092918E8 3.04E7 0.47 5.86250361E8 2.05E7 0.46 0.6616 0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P12 mock treatment 5.42696804E8 1.1E7 0.17 5.78174821E8 1.24E7 0.28 0.319 0.9717 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P13 compound treatment 5.31931009E8 198000.0 0.0 5.69272593E8 3500000.0 0.08 0.0581 0.734 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P14 compound treatment 5.50498011E8 1.88E7 0.29 5.82624963E8 1.69E7 0.38 0.476 0.9914 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P15 compound treatment 5.33275984E8 1540000.0 0.02 5.81631909E8 1.59E7 0.36 0.2705 0.7528 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P16 compound treatment 5.53684309E8 2.2E7 0.34 5.79563767E8 1.38E7 0.31 0.4622 0.9989 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P17 compound treatment 5.24599218E8 -7130000.0 -0.11 5.53306521E8 -1.25E7 -0.28 -0.2778 -0.9173 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P18 compound treatment 5.70085625E8 3.84E7 0.6 5.81332227E8 1.56E7 0.35 0.6711 0.9681 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P19 compound treatment 5.31555606E8 -178000.0 0.0 5.69146208E8 3380000.0 0.08 0.052 0.681 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P20 compound treatment 5.57344746E8 2.56E7 0.4 5.73207002E8 7440000.0 0.17 0.4009 0.9262 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P21 compound treatment 5.37866381E8 6130000.0 0.1 5.53334684E8 -1.24E7 -0.28 -0.1312 -0.442 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P22 compound treatment 5.44900726E8 1.32E7 0.21 5.82552122E8 1.68E7 0.38 0.4132 0.9583 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P23 compound treatment 5.3611689E8 4380000.0 0.07 5.56714491E8 -9060000.0 -0.2 -0.0965 -0.447 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2101 P24 compound treatment 5.210827E8 -1.07E7 -0.17 5.41766779E8 -2.4E7 -0.54 -0.5009 -0.883 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A01 compound treatment 5.36014288E8 -2.13E7 -0.33 5.33226903E8 -7760000.0 -0.18 -0.3587 -0.9556 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A02 compound treatment 5.62215167E8 4900000.0 0.08 5.59480053E8 1.85E7 0.42 0.3494 0.8226 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A03 compound treatment 5.23987247E8 -3.33E7 -0.52 5.21993979E8 -1.9E7 -0.43 -0.6707 -0.9955 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A04 compound treatment 5.70875453E8 1.36E7 0.21 5.37850505E8 -3140000.0 -0.07 0.0992 0.4452 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A05 compound treatment 5.49822753E8 -7500000.0 -0.12 5.18002406E8 -2.3E7 -0.52 -0.4499 -0.8449 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A06 compound treatment 5.8399145E8 2.67E7 0.42 5.28266757E8 -1.27E7 -0.29 0.0905 0.1791 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A07 compound treatment 5.27799857E8 -2.95E7 -0.46 4.93543868E8 -4.74E7 -1.07 -1.0833 -0.9285 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A08 compound treatment 5.01517584E8 -5.58E7 -0.87 5.01562684E8 -3.94E7 -0.89 -1.2446 -0.9999 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A09 compound treatment 5.31610929E8 -2.57E7 -0.4 5.22045338E8 -1.89E7 -0.43 -0.5859 -0.9994 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A10 compound treatment 5.19393474E8 -3.79E7 -0.59 5.26998004E8 -1.4E7 -0.32 -0.6413 -0.9571 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A11 compound treatment 5.44536035E8 -1.28E7 -0.2 5.27027252E8 -1.4E7 -0.32 -0.3639 -0.9753 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A12 compound treatment 5.26136999E8 -3.12E7 -0.49 5.206458E8 -2.03E7 -0.46 -0.6685 -0.9996 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A13 mock treatment 5.42690952E8 -1.46E7 -0.23 5.42038385E8 1050000.0 0.02 -0.1443 -0.6301 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A14 mock treatment 5.70831651E8 1.35E7 0.21 5.46768137E8 5780000.0 0.13 0.2412 0.9737 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A15 compound treatment 5.12563125E8 -4.48E7 -0.7 4.77911735E8 -6.31E7 -1.43 -1.5009 -0.9459 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A16 compound treatment 5.10950417E8 -4.64E7 -0.72 4.89702296E8 -5.13E7 -1.16 -1.3303 -0.9741 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A17 compound treatment 4.8847468E8 -6.88E7 -1.07 4.9100431E8 -5.0E7 -1.13 -1.557 -0.9997 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A18 compound treatment 4.84822818E8 -7.25E7 -1.13 4.92859879E8 -4.81E7 -1.09 -1.5676 -0.9998 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A19 compound treatment 4.91452394E8 -6.59E7 -1.03 5.01014364E8 -4.0E7 -0.9 -1.3643 -0.998 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A20 compound treatment 4.92661921E8 -6.47E7 -1.01 5.05658793E8 -3.53E7 -0.8 -1.2767 -0.9934 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A21 compound treatment 5.33457091E8 -2.39E7 -0.37 5.21402717E8 -1.96E7 -0.44 -0.5758 -0.9962 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A22 compound treatment 4.86217735E8 -7.11E7 -1.11 4.79864876E8 -6.11E7 -1.38 -1.7599 -0.994 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A23 compound treatment 4.97957458E8 -5.94E7 -0.92 4.92789671E8 -4.82E7 -1.09 -1.424 -0.9967 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 A24 compound treatment 5.06484061E8 -5.08E7 -0.79 4.9219086E8 -4.88E7 -1.1 -1.3397 -0.9868 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B01 compound treatment 5.13292809E8 -4.4E7 -0.69 4.88617119E8 -5.24E7 -1.18 -1.3218 -0.9663 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B02 compound treatment 5.35093423E8 -2.22E7 -0.35 5.07247446E8 -3.37E7 -0.76 -0.784 -0.9362 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B03 compound treatment 5.25083508E8 -3.22E7 -0.5 5.2060805E8 -2.04E7 -0.46 -0.6807 -0.9991 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B04 compound treatment 5.23344374E8 -3.4E7 -0.53 5.21330103E8 -1.97E7 -0.44 -0.6883 -0.9962 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B05 compound treatment 5.26883004E8 -3.04E7 -0.47 5.18052887E8 -2.29E7 -0.52 -0.7017 -0.999 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B06 compound treatment 5.43534493E8 -1.38E7 -0.21 5.32757123E8 -8230000.0 -0.19 -0.2834 -0.9975 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B07 compound treatment 5.18989277E8 -3.83E7 -0.6 5.29874518E8 -1.11E7 -0.25 -0.5998 -0.926 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B08 compound treatment 5.3308652E8 -2.42E7 -0.38 5.37492124E8 -3500000.0 -0.08 -0.3228 -0.837 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B09 compound treatment 5.08364837E8 -4.9E7 -0.76 5.03891604E8 -3.71E7 -0.84 -1.132 -0.9989 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B10 compound treatment 5.14522086E8 -4.28E7 -0.67 5.03294376E8 -3.77E7 -0.85 -1.0737 -0.9926 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B11 compound treatment 5.13945245E8 -4.34E7 -0.68 5.03283727E8 -3.77E7 -0.85 -1.0803 -0.9934 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B12 compound treatment 5.26941354E8 -3.04E7 -0.47 5.00285671E8 -4.07E7 -0.92 -0.985 -0.9522 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B13 mock treatment 5.4209996E8 -1.52E7 -0.24 5.34505414E8 -6480000.0 -0.15 -0.2712 -0.9733 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B14 mock treatment 5.68121411E8 1.08E7 0.17 5.23098443E8 -1.79E7 -0.4 -0.1669 -0.3811 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B15 compound treatment 5.01402855E8 -5.59E7 -0.87 5.19144057E8 -2.18E7 -0.49 -0.9649 -0.9638 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B16 compound treatment 5.04258265E8 -5.31E7 -0.83 5.09618541E8 -3.14E7 -0.71 -1.0857 -0.9971 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B17 compound treatment 5.11283756E8 -4.6E7 -0.72 4.9049071E8 -5.05E7 -1.14 -1.314 -0.9749 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B18 compound treatment 5.33580167E8 -2.37E7 -0.37 5.1637001E8 -2.46E7 -0.56 -0.6549 -0.9803 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B19 compound treatment 4.82866787E8 -7.45E7 -1.16 4.9413755E8 -4.69E7 -1.06 -1.5687 -0.999 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B20 compound treatment 4.82682104E8 -7.46E7 -1.16 4.86053438E8 -5.49E7 -1.24 -1.6999 -0.9995 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B21 compound treatment 5.15358282E8 -4.2E7 -0.65 5.14494379E8 -2.65E7 -0.6 -0.8855 -0.999 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B22 compound treatment 5.08565859E8 -4.88E7 -0.76 5.1046418E8 -3.05E7 -0.69 -1.0248 -0.9989 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B23 compound treatment 5.08677963E8 -4.86E7 -0.76 4.81915851E8 -5.91E7 -1.34 -1.4797 -0.964 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 B24 compound treatment 5.03988447E8 -5.33E7 -0.83 5.00639192E8 -4.03E7 -0.91 -1.2322 -0.9989 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C01 compound treatment 5.59570593E8 2250000.0 0.04 5.56071753E8 1.51E7 0.34 0.2658 0.7758 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C02 compound treatment 5.74251827E8 1.69E7 0.26 5.36184925E8 -4800000.0 -0.11 0.1097 0.3847 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C03 compound treatment 5.58895662E8 1580000.0 0.02 5.39484712E8 -1500000.0 -0.03 -0.0067 -0.1588 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C04 compound treatment 5.82661593E8 2.53E7 0.39 5.59406928E8 1.84E7 0.42 0.5735 0.9996 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C05 compound treatment 5.72833053E8 1.55E7 0.24 5.32400106E8 -8590000.0 -0.19 0.0336 0.1085 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C06 compound treatment 5.3605225E8 -2.13E7 -0.33 5.41037587E8 48900.0 0.0 -0.2334 -0.7047 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C07 compound treatment 5.7011645E8 1.28E7 0.2 5.47960028E8 6970000.0 0.16 0.2524 0.9932 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C08 compound treatment 5.77892459E8 2.06E7 0.32 5.44239162E8 3250000.0 0.07 0.2785 0.8472 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C09 compound treatment 5.54991309E8 -2330000.0 -0.04 5.42189067E8 1200000.0 0.03 -0.0064 -0.1424 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C10 compound treatment 5.62567165E8 5250000.0 0.08 5.20620294E8 -2.04E7 -0.46 -0.2677 -0.5726 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C11 mock treatment 5.68988404E8 1.17E7 0.18 5.78807364E8 3.78E7 0.85 0.7329 0.8387 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C12 mock treatment 5.77866536E8 2.05E7 0.32 5.72637831E8 3.16E7 0.72 0.7321 0.9342 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C13 compound treatment 5.4040209E8 -1.69E7 -0.26 5.21768837E8 -1.92E7 -0.43 -0.4935 -0.9713 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C14 compound treatment 5.46143046E8 -1.12E7 -0.17 5.30411564E8 -1.06E7 -0.24 -0.2921 -0.9879 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C15 mock treatment 5.8561233E8 2.83E7 0.44 5.83029827E8 4.2E7 0.95 0.9835 0.939 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C16 mock treatment 5.6229889E8 4980000.0 0.08 5.91258525E8 5.03E7 1.14 0.8582 0.7536 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C17 compound treatment 5.26315875E8 -3.1E7 -0.48 5.19969778E8 -2.1E7 -0.48 -0.6774 -1.0 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C18 compound treatment 5.01979608E8 -5.53E7 -0.86 5.03407216E8 -3.76E7 -0.85 -1.2101 -1.0 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C19 compound treatment 5.38444158E8 -1.89E7 -0.29 5.28215688E8 -1.28E7 -0.29 -0.412 -1.0 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C20 compound treatment 5.51781772E8 -5540000.0 -0.09 5.24011243E8 -1.7E7 -0.38 -0.3323 -0.845 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C21 compound treatment 5.22291234E8 -3.5E7 -0.55 5.14047701E8 -2.69E7 -0.61 -0.8163 -0.9985 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C22 compound treatment 5.42959111E8 -1.44E7 -0.22 5.43274868E8 2290000.0 0.05 -0.1216 -0.5298 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C23 compound treatment 5.29236614E8 -2.81E7 -0.44 5.36955031E8 -4030000.0 -0.09 -0.3737 -0.8365 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 C24 compound treatment 5.14332365E8 -4.3E7 -0.67 5.21316947E8 -1.97E7 -0.44 -0.7878 -0.9802 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D01 compound treatment 5.37608688E8 -1.97E7 -0.31 5.37138064E8 -3850000.0 -0.09 -0.2786 -0.8731 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D02 compound treatment 5.3022393E8 -2.71E7 -0.42 5.42185946E8 1200000.0 0.03 -0.2793 -0.6604 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D03 compound treatment 5.39694767E8 -1.76E7 -0.27 5.37101062E8 -3890000.0 -0.09 -0.2562 -0.889 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D04 compound treatment 5.27951975E8 -2.94E7 -0.46 5.79959131E8 3.9E7 0.88 0.2993 0.3016 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D05 compound treatment 5.66303229E8 8980000.0 0.14 5.66291117E8 2.53E7 0.57 0.5033 0.8549 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D06 compound treatment 5.66632229E8 9310000.0 0.15 5.63486518E8 2.25E7 0.51 0.4621 0.874 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D07 compound treatment 5.91380027E8 3.41E7 0.53 5.8435335E8 4.34E7 0.98 1.0681 0.9585 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D08 compound treatment 5.79508381E8 2.22E7 0.35 5.98862242E8 5.79E7 1.31 1.1693 0.8643 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D09 compound treatment 5.34719779E8 -2.26E7 -0.35 5.52591197E8 1.16E7 0.26 -0.0635 -0.1446 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D10 compound treatment 5.56105352E8 -1210000.0 -0.02 5.70440021E8 2.95E7 0.67 0.4573 0.6868 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D11 mock treatment 5.75051153E8 1.77E7 0.28 5.7556219E8 3.46E7 0.78 0.7478 0.9023 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D12 mock treatment 5.63578016E8 6260000.0 0.1 5.70967094E8 3.0E7 0.68 0.548 0.8006 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D13 compound treatment 5.25681238E8 -3.16E7 -0.49 5.4420886E8 3220000.0 0.07 -0.297 -0.5962 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D14 compound treatment 5.51621795E8 -5700000.0 -0.09 5.73120837E8 3.21E7 0.73 0.4508 0.6161 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D15 mock treatment 5.90187664E8 3.29E7 0.51 5.69419359E8 2.84E7 0.64 0.8164 0.9937 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D16 mock treatment 5.82475537E8 2.52E7 0.39 5.69185272E8 2.82E7 0.64 0.7277 0.9727 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D17 compound treatment 5.0986663E8 -4.75E7 -0.74 5.38732914E8 -2260000.0 -0.05 -0.5587 -0.7541 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D18 compound treatment 5.56243724E8 -1070000.0 -0.02 5.91336625E8 5.03E7 1.14 0.7928 0.6966 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D19 compound treatment 5.38058958E8 -1.93E7 -0.3 5.41621588E8 633000.0 0.01 -0.202 -0.6726 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D20 compound treatment 5.22679831E8 -3.46E7 -0.54 5.43736487E8 2750000.0 0.06 -0.3376 -0.6216 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D21 compound treatment 5.40227506E8 -1.71E7 -0.27 5.49758371E8 8770000.0 0.2 -0.0481 -0.1449 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D22 compound treatment 5.40378205E8 -1.69E7 -0.26 5.34910109E8 -6080000.0 -0.14 -0.2837 -0.9537 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D23 compound treatment 5.09764498E8 -4.76E7 -0.74 5.12862194E8 -2.81E7 -0.64 -0.9732 -0.9971 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 D24 compound treatment 5.53964848E8 -3350000.0 -0.05 5.42719806E8 1730000.0 0.04 -0.0093 -0.142 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E01 mock treatment 5.45050816E8 -1.23E7 -0.19 5.59996992E8 1.9E7 0.43 0.1687 0.3587 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E02 mock treatment 5.30634138E8 -2.67E7 -0.42 5.28238036E8 -1.28E7 -0.29 -0.4977 -0.984 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E03 compound treatment 5.21865995E8 -3.55E7 -0.55 5.21327303E8 -1.97E7 -0.44 -0.7047 -0.9942 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E04 compound treatment 4.87783571E8 -6.95E7 -1.08 4.94074534E8 -4.69E7 -1.06 -1.5156 -0.9999 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E05 compound treatment 5.36950902E8 -2.04E7 -0.32 5.1367219E8 -2.73E7 -0.62 -0.6609 -0.9521 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E06 compound treatment 5.30608608E8 -2.67E7 -0.42 5.2336059E8 -1.76E7 -0.4 -0.5759 -0.9998 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E07 compound treatment 5.32708063E8 -2.46E7 -0.38 4.90014215E8 -5.1E7 -1.15 -1.0857 -0.8942 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E08 compound treatment 5.02512235E8 -5.48E7 -0.85 5.05301174E8 -3.57E7 -0.81 -1.1739 -0.9996 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E09 mock treatment 5.46836909E8 -1.05E7 -0.16 5.12196901E8 -2.88E7 -0.65 -0.5756 -0.8579 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E10 mock treatment 5.65454693E8 8140000.0 0.13 5.10268683E8 -3.07E7 -0.69 -0.4013 -0.5686 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E11 compound treatment 4.94635378E8 -6.27E7 -0.98 5.04895362E8 -3.61E7 -0.82 -1.2672 -0.996 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E12 compound treatment 5.15181538E8 -4.21E7 -0.66 5.21780182E8 -1.92E7 -0.43 -0.7711 -0.9799 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E13 compound treatment 4.75960756E8 -8.14E7 -1.27 4.71893214E8 -6.91E7 -1.56 -2.0003 -0.9946 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E14 compound treatment 5.18957701E8 -3.84E7 -0.6 5.18481146E8 -2.25E7 -0.51 -0.7822 -0.9968 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E15 compound treatment 5.14267199E8 -4.31E7 -0.67 5.14631631E8 -2.64E7 -0.6 -0.8954 -0.9983 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E16 compound treatment 5.34116611E8 -2.32E7 -0.36 5.03740765E8 -3.72E7 -0.84 -0.8508 -0.9287 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E17 mock treatment 5.24945445E8 -3.24E7 -0.5 5.12428377E8 -2.86E7 -0.65 -0.813 -0.9925 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E18 mock treatment 5.46597526E8 -1.07E7 -0.17 5.38655502E8 -2330000.0 -0.05 -0.1554 -0.8872 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E19 compound treatment 4.86343419E8 -7.1E7 -1.11 4.5915402E8 -8.18E7 -1.85 -2.0895 -0.9697 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E20 compound treatment 5.3666939E8 -2.06E7 -0.32 5.19137884E8 -2.19E7 -0.49 -0.5766 -0.9784 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E21 compound treatment 5.14083459E8 -4.32E7 -0.67 4.91211331E8 -4.98E7 -1.12 -1.2717 -0.9699 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E22 compound treatment 4.94305749E8 -6.3E7 -0.98 4.86368713E8 -5.46E7 -1.23 -1.5669 -0.9935 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E23 compound treatment 5.0850454E8 -4.88E7 -0.76 4.88916662E8 -5.21E7 -1.18 -1.3698 -0.9777 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 E24 compound treatment 4.95711977E8 -6.16E7 -0.96 4.70071729E8 -7.09E7 -1.6 -1.8118 -0.9699 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F01 mock treatment 5.84376766E8 2.71E7 0.42 5.56961204E8 1.6E7 0.36 0.5533 0.997 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F02 mock treatment 5.43837795E8 -1.35E7 -0.21 5.74496115E8 3.35E7 0.76 0.387 0.4925 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F03 compound treatment 5.57779622E8 461000.0 0.01 5.25203703E8 -1.58E7 -0.36 -0.2472 -0.6927 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F04 compound treatment 5.20671342E8 -3.66E7 -0.57 5.38233015E8 -2760000.0 -0.06 -0.4477 -0.7796 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F05 compound treatment 5.43658943E8 -1.37E7 -0.21 5.57580387E8 1.66E7 0.37 0.1147 0.2661 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F06 compound treatment 5.26193139E8 -3.11E7 -0.48 5.35639177E8 -5350000.0 -0.12 -0.4283 -0.8572 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F07 compound treatment 5.52130673E8 -5190000.0 -0.08 5.11384201E8 -2.96E7 -0.67 -0.5302 -0.7868 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F08 compound treatment 5.67233221E8 9910000.0 0.15 5.39965873E8 -1020000.0 -0.02 0.0929 0.5946 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F09 mock treatment 5.56335539E8 -983000.0 -0.02 5.28151155E8 -1.28E7 -0.29 -0.216 -0.7434 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F10 mock treatment 5.7276336E8 1.54E7 0.24 5.40207069E8 -782000.0 -0.02 0.1576 0.6534 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F11 compound treatment 5.57753175E8 435000.0 0.01 5.08667952E8 -3.23E7 -0.73 -0.5117 -0.7005 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F12 compound treatment 5.54807747E8 -2510000.0 -0.04 5.37933687E8 -3050000.0 -0.07 -0.0765 -0.9638 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F13 compound treatment 5.3267394E8 -2.46E7 -0.38 4.95703459E8 -4.53E7 -1.02 -0.9951 -0.9104 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F14 compound treatment 5.33647655E8 -2.37E7 -0.37 5.20203516E8 -2.08E7 -0.47 -0.5929 -0.9928 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F15 compound treatment 5.39108279E8 -1.82E7 -0.28 5.12930629E8 -2.81E7 -0.63 -0.6489 -0.9342 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F16 compound treatment 5.54442534E8 -2880000.0 -0.04 5.11832948E8 -2.92E7 -0.66 -0.4976 -0.7534 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F17 mock treatment 5.63704963E8 6390000.0 0.1 5.35746208E8 -5240000.0 -0.12 -0.0134 -0.0869 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F18 mock treatment 5.4764968E8 -9670000.0 -0.15 5.26826338E8 -1.42E7 -0.32 -0.3328 -0.9409 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F19 compound treatment 5.13427515E8 -4.39E7 -0.68 5.14538704E8 -2.64E7 -0.6 -0.9061 -0.9978 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F20 compound treatment 5.5283683E8 -4480000.0 -0.07 5.41324412E8 336000.0 0.01 -0.044 -0.6266 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F21 compound treatment 5.28318079E8 -2.9E7 -0.45 5.04407689E8 -3.66E7 -0.83 -0.904 -0.9596 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F22 compound treatment 5.19612654E8 -3.77E7 -0.59 5.03105435E8 -3.79E7 -0.86 -1.0207 -0.9831 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F23 compound treatment 5.51688498E8 -5630000.0 -0.09 5.1344419E8 -2.75E7 -0.62 -0.5022 -0.7988 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 F24 compound treatment 5.26310929E8 -3.1E7 -0.48 4.91653197E8 -4.93E7 -1.11 -1.1299 -0.9299 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G01 compound treatment 5.15475874E8 -4.18E7 -0.65 4.95974941E8 -4.5E7 -1.02 -1.1802 -0.9768 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G02 compound treatment 5.5478922E8 -2530000.0 -0.04 5.25824389E8 -1.52E7 -0.34 -0.2702 -0.7832 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G03 mock treatment 6.0727172E8 5.0E7 0.78 5.59234911E8 1.82E7 0.41 0.8418 0.9559 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G04 mock treatment 5.98755228E8 4.14E7 0.65 5.59792559E8 1.88E7 0.42 0.7569 0.9794 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G05 compound treatment 5.47308257E8 -1.0E7 -0.16 5.01819258E8 -3.92E7 -0.89 -0.7362 -0.819 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G06 compound treatment 5.70812578E8 1.35E7 0.21 5.16603142E8 -2.44E7 -0.55 -0.2411 -0.4087 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G07 compound treatment 5.56110082E8 -1210000.0 -0.02 5.16653735E8 -2.43E7 -0.55 -0.4022 -0.7309 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G08 compound treatment 5.64630888E8 7310000.0 0.11 5.47030141E8 6040000.0 0.14 0.1771 0.9959 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G09 compound treatment 5.41308618E8 -1.6E7 -0.25 5.42567699E8 1580000.0 0.04 -0.1511 -0.5998 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G10 compound treatment 5.66628783E8 9310000.0 0.15 5.55024552E8 1.4E7 0.32 0.3268 0.9371 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G11 compound treatment 5.67592218E8 1.03E7 0.16 5.3008287E8 -1.09E7 -0.25 -0.0611 -0.208 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G12 compound treatment 5.73382045E8 1.61E7 0.25 5.72162401E8 3.12E7 0.7 0.6751 0.903 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G13 compound treatment 5.18938814E8 -3.84E7 -0.6 4.86026198E8 -5.5E7 -1.24 -1.301 -0.9438 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G14 compound treatment 5.3366897E8 -2.36E7 -0.37 5.09856625E8 -3.11E7 -0.7 -0.758 -0.9544 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G15 compound treatment 5.58585109E8 1270000.0 0.02 5.33400736E8 -7590000.0 -0.17 -0.1073 -0.6216 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G16 compound treatment 5.86046543E8 2.87E7 0.45 5.32694662E8 -8290000.0 -0.19 0.1839 0.379 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G17 compound treatment 5.08571369E8 -4.87E7 -0.76 5.21889903E8 -1.91E7 -0.43 -0.8421 -0.9642 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G18 compound treatment 5.31776116E8 -2.55E7 -0.4 5.32662671E8 -8330000.0 -0.19 -0.4144 -0.9415 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G19 mock treatment 5.64796892E8 7480000.0 0.12 5.51316265E8 1.03E7 0.23 0.2474 0.9484 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G20 mock treatment 5.77916565E8 2.06E7 0.32 5.72886376E8 3.19E7 0.72 0.7366 0.9335 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G21 compound treatment 5.28745791E8 -2.86E7 -0.45 5.06018943E8 -3.5E7 -0.79 -0.8735 -0.9631 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G22 compound treatment 5.23856811E8 -3.35E7 -0.52 5.25236055E8 -1.58E7 -0.36 -0.6203 -0.9827 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G23 compound treatment 5.12318652E8 -4.5E7 -0.7 5.07662236E8 -3.33E7 -0.75 -1.0282 -0.9994 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 G24 compound treatment 5.09420298E8 -4.79E7 -0.75 4.96091614E8 -4.49E7 -1.01 -1.245 -0.9886 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H01 compound treatment 5.53828637E8 -3490000.0 -0.05 5.45564333E8 4580000.0 0.1 0.0347 0.2969 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H02 compound treatment 5.58942478E8 1620000.0 0.03 5.5294987E8 1.2E7 0.27 0.209 0.7699 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H03 mock treatment 6.22690037E8 6.54E7 1.02 6.23311692E8 8.23E7 1.86 2.0356 0.9598 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H04 mock treatment 6.12874006E8 5.56E7 0.87 5.8641509E8 4.54E7 1.03 1.3378 0.9964 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H05 compound treatment 5.80292448E8 2.3E7 0.36 6.07813998E8 6.68E7 1.51 1.3209 0.8511 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H06 compound treatment 6.12363735E8 5.5E7 0.86 5.6556031E8 2.46E7 0.56 0.9989 0.9779 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H07 compound treatment 5.5439802E8 -2920000.0 -0.05 5.79264799E8 3.83E7 0.87 0.5795 0.669 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H08 compound treatment 6.00014978E8 4.27E7 0.67 5.79377573E8 3.84E7 0.87 1.0837 0.9914 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H09 compound treatment 6.11664495E8 5.43E7 0.85 5.45037669E8 4050000.0 0.09 0.6633 0.779 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H10 compound treatment 5.65769282E8 8450000.0 0.13 5.62657454E8 2.17E7 0.49 0.4394 0.8664 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H11 compound treatment 5.51633398E8 -5680000.0 -0.09 5.46210113E8 5220000.0 0.12 0.0208 0.1412 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H12 compound treatment 6.0026276E8 4.29E7 0.67 5.85317674E8 4.43E7 1.0 1.1814 0.9807 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H13 compound treatment 5.87607753E8 3.03E7 0.47 6.09410831E8 6.84E7 1.55 1.427 0.8827 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H14 compound treatment 5.50871228E8 -6450000.0 -0.1 5.4797883E8 6990000.0 0.16 0.0407 0.2174 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H15 compound treatment 5.19602265E8 -3.77E7 -0.59 5.17428662E8 -2.36E7 -0.53 -0.7919 -0.9988 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H16 compound treatment 5.54902565E8 -2420000.0 -0.04 5.62870628E8 2.19E7 0.49 0.3231 0.6514 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H17 compound treatment 5.72568171E8 1.52E7 0.24 5.40386423E8 -602000.0 -0.01 0.1583 0.6655 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H18 compound treatment 5.46718282E8 -1.06E7 -0.17 5.32136639E8 -8850000.0 -0.2 -0.2582 -0.9955 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H19 mock treatment 5.71812612E8 1.45E7 0.23 5.69420103E8 2.84E7 0.64 0.614 0.9015 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H20 mock treatment 5.78000258E8 2.07E7 0.32 5.51045472E8 1.01E7 0.23 0.3885 0.9854 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H21 compound treatment 5.42955544E8 -1.44E7 -0.22 5.60189119E8 1.92E7 0.43 0.1486 0.3045 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H22 compound treatment 5.5515417E8 -2160000.0 -0.03 5.38533219E8 -2460000.0 -0.06 -0.0631 -0.9715 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H23 compound treatment 5.44409787E8 -1.29E7 -0.2 5.37024398E8 -3960000.0 -0.09 -0.2055 -0.9337 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 H24 compound treatment 5.41990299E8 -1.53E7 -0.24 5.48014687E8 7030000.0 0.16 -0.0565 -0.1972 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I01 compound treatment 4.91696179E8 -6.56E7 -1.02 4.53774451E8 -8.72E7 -1.97 -2.1165 -0.9532 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I02 compound treatment 5.19272352E8 -3.8E7 -0.59 4.85300402E8 -5.57E7 -1.26 -1.309 -0.941 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I03 compound treatment 4.55969521E8 -1.01E8 -1.58 4.55378402E8 -8.56E7 -1.93 -2.4844 -0.9949 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I04 compound treatment 4.65146601E8 -9.22E7 -1.44 4.7724291E8 -6.37E7 -1.44 -2.0339 -1.0 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I05 mock treatment 5.49918256E8 -7400000.0 -0.12 5.03564253E8 -3.74E7 -0.85 -0.6796 -0.7961 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I06 mock treatment 5.35926876E8 -2.14E7 -0.33 5.20029821E8 -2.1E7 -0.47 -0.5705 -0.9852 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I07 compound treatment 5.37698342E8 -1.96E7 -0.31 4.68424522E8 -7.26E7 -1.64 -1.3757 -0.8247 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I08 compound treatment 5.3988509E8 -1.74E7 -0.27 5.16528627E8 -2.45E7 -0.55 -0.5829 -0.9464 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I09 compound treatment 4.95635532E8 -6.17E7 -0.96 4.8913315E8 -5.19E7 -1.17 -1.5081 -0.9951 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I10 compound treatment 4.94058858E8 -6.33E7 -0.99 4.81325543E8 -5.97E7 -1.35 -1.6502 -0.9881 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I11 compound treatment 5.2321474E8 -3.41E7 -0.53 5.20465152E8 -2.05E7 -0.46 -0.7036 -0.9977 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I12 compound treatment 4.76488627E8 -8.08E7 -1.26 4.90298213E8 -5.07E7 -1.15 -1.7003 -0.9989 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I13 compound treatment 5.00079173E8 -5.72E7 -0.89 5.00313979E8 -4.07E7 -0.92 -1.2804 -0.9999 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I14 compound treatment 5.36859906E8 -2.05E7 -0.32 5.14366545E8 -2.66E7 -0.6 -0.6508 -0.9558 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I15 compound treatment 4.73227265E8 -8.41E7 -1.31 4.68783828E8 -7.22E7 -1.63 -2.0801 -0.9941 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I16 compound treatment 4.93032095E8 -6.43E7 -1.0 4.79442122E8 -6.15E7 -1.39 -1.6916 -0.987 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I17 compound treatment 4.69965989E8 -8.74E7 -1.36 4.39563656E8 -1.01E8 -2.29 -2.5829 -0.969 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I18 compound treatment 5.09431372E8 -4.79E7 -0.75 5.09010139E8 -3.2E7 -0.72 -1.0385 -0.9999 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I19 compound treatment 5.01240295E8 -5.61E7 -0.87 5.03953814E8 -3.7E7 -0.84 -1.2095 -0.9998 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I20 compound treatment 5.09704435E8 -4.76E7 -0.74 4.99011092E8 -4.2E7 -0.95 -1.1952 -0.9926 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I21 mock treatment 5.36353988E8 -2.1E7 -0.33 5.09707789E8 -3.13E7 -0.71 -0.7308 -0.9384 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I22 mock treatment 5.18758178E8 -3.86E7 -0.6 5.1491307E8 -2.61E7 -0.59 -0.8414 -1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I23 compound treatment 4.94041603E8 -6.33E7 -0.99 4.84401634E8 -5.66E7 -1.28 -1.6012 -0.9917 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 I24 compound treatment 4.69751018E8 -8.76E7 -1.36 4.41088411E8 -9.99E7 -2.26 -2.5609 -0.9709 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J01 compound treatment 5.05451151E8 -5.19E7 -0.81 4.90413011E8 -5.06E7 -1.14 -1.3795 -0.9856 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J02 compound treatment 5.04431396E8 -5.29E7 -0.82 4.87547142E8 -5.34E7 -1.21 -1.4365 -0.9826 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J03 compound treatment 5.31622278E8 -2.57E7 -0.4 5.09012877E8 -3.2E7 -0.72 -0.794 -0.9612 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J04 compound treatment 5.75958802E8 1.86E7 0.29 5.43934263E8 2950000.0 0.07 0.2524 0.8472 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J05 mock treatment 5.96314867E8 3.9E7 0.61 5.40691638E8 -297000.0 -0.01 0.4248 0.6992 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J06 mock treatment 5.46268582E8 -1.1E7 -0.17 5.16774339E8 -2.42E7 -0.55 -0.5087 -0.8867 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J07 compound treatment 5.57310986E8 -7330.0 0.0 5.03115962E8 -3.79E7 -0.86 -0.6053 -0.7072 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J08 compound treatment 4.94992968E8 -6.23E7 -0.97 4.55532401E8 -8.55E7 -1.93 -2.0521 -0.9494 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J09 compound treatment 4.81572498E8 -7.57E7 -1.18 4.99454107E8 -4.15E7 -0.94 -1.498 -0.9936 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J10 compound treatment 5.51835038E8 -5480000.0 -0.09 5.2087594E8 -2.01E7 -0.45 -0.3818 -0.8255 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J11 compound treatment 4.96147064E8 -6.12E7 -0.95 5.18562294E8 -2.24E7 -0.51 -1.0321 -0.9564 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J12 compound treatment 4.99376965E8 -5.79E7 -0.9 4.8504599E8 -5.59E7 -1.26 -1.5322 -0.9863 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J13 compound treatment 5.21045801E8 -3.63E7 -0.56 5.26479404E8 -1.45E7 -0.33 -0.6314 -0.9665 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J14 compound treatment 5.48128604E8 -9190000.0 -0.14 4.70204027E8 -7.08E7 -1.6 -1.2324 -0.7673 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J15 compound treatment 4.7780289E8 -7.95E7 -1.24 4.40856635E8 -1.0E8 -2.26 -2.4759 -0.9598 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J16 compound treatment 4.93615625E8 -6.37E7 -0.99 4.72947537E8 -6.8E7 -1.54 -1.789 -0.9775 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J17 compound treatment 5.25026398E8 -3.23E7 -0.5 5.18549506E8 -2.24E7 -0.51 -0.7143 -1.0 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J18 compound treatment 5.0060768E8 -5.67E7 -0.88 4.93118205E8 -4.79E7 -1.08 -1.3896 -0.9949 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J19 compound treatment 5.09954523E8 -4.74E7 -0.74 5.06334822E8 -3.47E7 -0.78 -1.0755 -0.9996 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J20 compound treatment 5.14164503E8 -4.32E7 -0.67 4.90124372E8 -5.09E7 -1.15 -1.2881 -0.9673 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J21 mock treatment 5.46836449E8 -1.05E7 -0.16 5.31188024E8 -9800000.0 -0.22 -0.2721 -0.9887 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J22 mock treatment 5.44446497E8 -1.29E7 -0.2 5.3246608E8 -8520000.0 -0.19 -0.278 -0.9998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J23 compound treatment 5.07358723E8 -5.0E7 -0.78 5.00918617E8 -4.01E7 -0.91 -1.1906 -0.9971 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 J24 compound treatment 4.60980736E8 -9.63E7 -1.5 4.56903251E8 -8.41E7 -1.9 -2.4048 -0.9932 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K01 compound treatment 4.57015039E8 -1.0E8 -1.56 4.51247388E8 -8.97E7 -2.03 -2.5389 -0.9917 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K02 compound treatment 4.59260059E8 -9.81E7 -1.53 4.23392975E8 -1.18E8 -2.66 -2.9593 -0.9654 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K03 compound treatment 4.87179417E8 -7.01E7 -1.09 4.59978454E8 -8.1E7 -1.83 -2.0671 -0.9696 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K04 compound treatment 5.10652681E8 -4.67E7 -0.73 5.11127219E8 -2.99E7 -0.67 -0.9912 -0.9993 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K05 compound treatment 4.76349724E8 -8.1E7 -1.26 4.74815018E8 -6.62E7 -1.5 -1.9493 -0.9964 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K06 compound treatment 4.65947289E8 -9.14E7 -1.42 4.33279118E8 -1.08E8 -2.43 -2.7276 -0.9673 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K07 mock treatment 5.25797873E8 -3.15E7 -0.49 5.21983633E8 -1.9E7 -0.43 -0.6509 -0.9978 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K08 mock treatment 5.74097077E8 1.68E7 0.26 5.15290282E8 -2.57E7 -0.58 -0.2259 -0.3547 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K09 compound treatment 4.93598604E8 -6.37E7 -0.99 4.80921322E8 -6.01E7 -1.36 -1.6617 -0.9882 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K10 compound treatment 4.69084557E8 -8.82E7 -1.37 4.71409264E8 -6.96E7 -1.57 -2.0837 -0.9977 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K11 compound treatment 4.8491168E8 -7.24E7 -1.13 4.66871148E8 -7.41E7 -1.68 -1.9819 -0.9815 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K12 compound treatment 4.7737073E8 -7.99E7 -1.25 4.54576306E8 -8.64E7 -1.95 -2.2615 -0.9764 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K13 compound treatment 4.63984847E8 -9.33E7 -1.45 4.81416493E8 -5.96E7 -1.35 -1.98 -0.9993 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K14 compound treatment 4.79607341E8 -7.77E7 -1.21 4.77325973E8 -6.37E7 -1.44 -1.8733 -0.9963 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K15 mock treatment 5.26188661E8 -3.11E7 -0.48 5.0513839E8 -3.59E7 -0.81 -0.9158 -0.9699 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K16 mock treatment 5.17465013E8 -3.99E7 -0.62 5.09139579E8 -3.18E7 -0.72 -0.9479 -0.9973 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K17 compound treatment 4.84111977E8 -7.32E7 -1.14 4.55156938E8 -8.58E7 -1.94 -2.1779 -0.9679 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K18 compound treatment 4.75867582E8 -8.15E7 -1.27 4.63448839E8 -7.75E7 -1.75 -2.1362 -0.9874 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K19 compound treatment 5.13740221E8 -4.36E7 -0.68 5.00677607E8 -4.03E7 -0.91 -1.1242 -0.9895 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K20 compound treatment 4.65711661E8 -9.16E7 -1.43 4.74657823E8 -6.63E7 -1.5 -2.069 -0.9997 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K21 compound treatment 5.12311833E8 -4.5E7 -0.7 4.88673468E8 -5.23E7 -1.18 -1.3317 -0.9689 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K22 compound treatment 4.53593546E8 -1.04E8 -1.62 4.69671617E8 -7.13E7 -1.61 -2.2821 -1.0 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K23 mock treatment 5.20714669E8 -3.66E7 -0.57 5.34068921E8 -6920000.0 -0.16 -0.5137 -0.869 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 K24 mock treatment 5.19296217E8 -3.8E7 -0.59 4.95622059E8 -4.54E7 -1.03 -1.1438 -0.966 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L01 compound treatment 4.87595032E8 -6.97E7 -1.09 5.46792772E8 5800000.0 0.13 -0.6752 -0.6172 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L02 compound treatment 5.45152141E8 -1.22E7 -0.19 5.51306002E8 1.03E7 0.23 0.0309 0.1028 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L03 compound treatment 5.21515626E8 -3.58E7 -0.56 5.28553713E8 -1.24E7 -0.28 -0.593 -0.9497 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L04 compound treatment 5.62356163E8 5040000.0 0.08 6.11718702E8 7.07E7 1.6 1.1858 0.7409 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L05 compound treatment 5.48110046E8 -9210000.0 -0.14 5.3968832E8 -1300000.0 -0.03 -0.1222 -0.8347 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L06 compound treatment 5.49505399E8 -7810000.0 -0.12 5.59868869E8 1.89E7 0.43 0.2157 0.4861 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L07 mock treatment 5.68624186E8 1.13E7 0.18 5.43548048E8 2560000.0 0.06 0.1654 0.8925 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L08 mock treatment 5.53300988E8 -4020000.0 -0.06 5.49520718E8 8530000.0 0.19 0.0921 0.4543 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L09 compound treatment 4.91927348E8 -6.54E7 -1.02 5.3534942E8 -5640000.0 -0.13 -0.8103 -0.7894 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L10 compound treatment 4.86850962E8 -7.05E7 -1.1 5.21741189E8 -1.92E7 -0.43 -1.0837 -0.9179 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L11 compound treatment 4.93177415E8 -6.41E7 -1.0 5.21693635E8 -1.93E7 -0.44 -1.0148 -0.9309 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L12 compound treatment 5.30655001E8 -2.67E7 -0.42 5.23116425E8 -1.79E7 -0.4 -0.5793 -0.9999 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L13 compound treatment 4.67801368E8 -8.95E7 -1.39 4.91419295E8 -4.96E7 -1.12 -1.7781 -0.9941 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L14 compound treatment 5.45994516E8 -1.13E7 -0.18 5.62702861E8 2.17E7 0.49 0.2223 0.4263 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L15 mock treatment 5.48357966E8 -8960000.0 -0.14 5.61633272E8 2.06E7 0.47 0.2312 0.4748 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L16 mock treatment 5.4913307E8 -8190000.0 -0.13 5.66280123E8 2.53E7 0.57 0.314 0.5362 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L17 compound treatment 4.76788925E8 -8.05E7 -1.25 5.43176511E8 2190000.0 0.05 -0.852 -0.6787 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L18 compound treatment 5.62142051E8 4820000.0 0.08 5.1691963E8 -2.41E7 -0.54 -0.3315 -0.6037 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L19 compound treatment 4.59385778E8 -9.79E7 -1.53 4.73355647E8 -6.76E7 -1.53 -2.1594 -1.0 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L20 compound treatment 5.42538117E8 -1.48E7 -0.23 5.54813526E8 1.38E7 0.31 0.0581 0.1498 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L21 compound treatment 4.79660659E8 -7.77E7 -1.21 5.42396111E8 1410000.0 0.03 -0.8328 -0.6883 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L22 compound treatment 4.55398952E8 -1.02E8 -1.59 4.83520988E8 -5.75E7 -1.3 -2.0409 -0.995 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L23 mock treatment 5.3086191E8 -2.65E7 -0.41 5.28724802E8 -1.23E7 -0.28 -0.4874 -0.9814 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 L24 mock treatment 5.19038619E8 -3.83E7 -0.6 5.31544072E8 -9440000.0 -0.21 -0.5725 -0.9041 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M01 compound treatment 5.09312427E8 -4.8E7 -0.75 4.97031879E8 -4.4E7 -0.99 -1.2312 -0.9902 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M02 compound treatment 5.08550843E8 -4.88E7 -0.76 4.49586268E8 -9.14E7 -2.07 -1.9978 -0.9077 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M03 compound treatment 5.41366571E8 -1.6E7 -0.25 4.97139576E8 -4.38E7 -0.99 -0.8764 -0.8578 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M04 compound treatment 4.76031592E8 -8.13E7 -1.27 4.6144098E8 -7.95E7 -1.8 -2.1665 -0.9853 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M05 compound treatment 4.66305691E8 -9.1E7 -1.42 4.23409678E8 -1.18E8 -2.66 -2.8814 -0.9567 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M06 compound treatment 5.0171252E8 -5.56E7 -0.87 4.35736718E8 -1.05E8 -2.38 -2.2944 -0.9064 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M07 compound treatment 5.18167223E8 -3.92E7 -0.61 4.56597474E8 -8.44E7 -1.91 -1.7798 -0.8889 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M08 compound treatment 4.7737998E8 -7.99E7 -1.25 4.70691836E8 -7.03E7 -1.59 -2.0038 -0.9927 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M09 mock treatment 5.34232863E8 -2.31E7 -0.36 5.08684968E8 -3.23E7 -0.73 -0.7705 -0.9468 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M10 mock treatment 5.62398388E8 5080000.0 0.08 5.17677908E8 -2.33E7 -0.53 -0.3166 -0.5942 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M11 compound treatment 5.22289413E8 -3.5E7 -0.55 5.05870727E8 -3.51E7 -0.79 -0.947 -0.9833 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M12 compound treatment 5.18327459E8 -3.9E7 -0.61 4.76666252E8 -6.43E7 -1.45 -1.4574 -0.925 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M13 mock treatment 5.41817308E8 -1.55E7 -0.24 5.215843E8 -1.94E7 -0.44 -0.4808 -0.9605 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M14 mock treatment 5.42533352E8 -1.48E7 -0.23 5.17132707E8 -2.39E7 -0.54 -0.5441 -0.928 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M15 compound treatment 4.64397388E8 -9.29E7 -1.45 4.34257701E8 -1.07E8 -2.41 -2.7291 -0.9701 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M16 compound treatment 4.98984419E8 -5.83E7 -0.91 4.81343159E8 -5.96E7 -1.35 -1.5957 -0.9816 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M17 compound treatment 4.75346325E8 -8.2E7 -1.28 4.4761302E8 -9.34E7 -2.11 -2.395 -0.971 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M18 compound treatment 4.56728863E8 -1.01E8 -1.57 4.42821916E8 -9.82E7 -2.22 -2.6767 -0.9855 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M19 compound treatment 5.24263995E8 -3.31E7 -0.51 4.99920012E8 -4.11E7 -0.93 -1.0204 -0.9613 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M20 compound treatment 4.55748014E8 -1.02E8 -1.58 4.34222678E8 -1.07E8 -2.41 -2.8249 -0.9791 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M21 compound treatment 4.87793643E8 -6.95E7 -1.08 4.83926395E8 -5.71E7 -1.29 -1.6776 -0.9962 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M22 compound treatment 5.17990535E8 -3.93E7 -0.61 4.92169786E8 -4.88E7 -1.1 -1.2133 -0.9615 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M23 compound treatment 5.10039909E8 -4.73E7 -0.74 4.80063657E8 -6.09E7 -1.38 -1.4943 -0.957 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 M24 compound treatment 4.61721065E8 -9.56E7 -1.49 4.40674565E8 -1.0E8 -2.27 -2.656 -0.9792 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N01 compound treatment 5.12847498E8 -4.45E7 -0.69 4.89109452E8 -5.19E7 -1.17 -1.3189 -0.9685 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N02 compound treatment 5.3466704E8 -2.27E7 -0.35 5.50931252E8 9940000.0 0.22 -0.0906 -0.2166 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N03 compound treatment 5.13588556E8 -4.37E7 -0.68 5.23342044E8 -1.76E7 -0.4 -0.7636 -0.9675 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N04 compound treatment 5.59970103E8 2650000.0 0.04 5.39803688E8 -1180000.0 -0.03 0.0103 0.2086 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N05 compound treatment 4.71892071E8 -8.54E7 -1.33 4.87610376E8 -5.34E7 -1.21 -1.7939 -0.9988 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N06 compound treatment 5.5973585E8 2420000.0 0.04 5.45687288E8 4700000.0 0.11 0.1017 0.9028 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N07 compound treatment 5.24718164E8 -3.26E7 -0.51 5.20029547E8 -2.1E7 -0.47 -0.694 -0.9994 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N08 compound treatment 4.99001485E8 -5.83E7 -0.91 4.75438373E8 -6.56E7 -1.48 -1.6898 -0.9724 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N09 mock treatment 5.81162971E8 2.38E7 0.37 5.47511478E8 6520000.0 0.15 0.3669 0.9181 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N10 mock treatment 5.54369278E8 -2950000.0 -0.05 5.24092953E8 -1.69E7 -0.38 -0.3025 -0.7865 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N11 compound treatment 5.19138896E8 -3.82E7 -0.59 5.19022139E8 -2.2E7 -0.5 -0.7715 -0.996 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N12 compound treatment 5.23454507E8 -3.39E7 -0.53 5.24217E8 -1.68E7 -0.38 -0.641 -0.9869 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N13 mock treatment 5.53412516E8 -3910000.0 -0.06 5.12142018E8 -2.88E7 -0.65 -0.504 -0.7697 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N14 mock treatment 5.4103211E8 -1.63E7 -0.25 5.16569986E8 -2.44E7 -0.55 -0.5696 -0.9378 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N15 compound treatment 4.84646871E8 -7.27E7 -1.13 4.99867222E8 -4.11E7 -0.93 -1.4575 -0.9952 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N16 compound treatment 5.67548243E8 1.02E7 0.16 5.28615001E8 -1.24E7 -0.28 -0.0851 -0.2643 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N17 compound treatment 5.09736063E8 -4.76E7 -0.74 5.05971718E8 -3.5E7 -0.79 -1.0837 -0.9995 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N18 compound treatment 4.90846092E8 -6.65E7 -1.04 4.77731422E8 -6.33E7 -1.43 -1.743 -0.9875 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N19 compound treatment 4.92506959E8 -6.48E7 -1.01 4.82129775E8 -5.89E7 -1.33 -1.6544 -0.9907 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N20 compound treatment 5.5686241E8 -456000.0 -0.01 5.25263741E8 -1.57E7 -0.36 -0.2563 -0.7211 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N21 compound treatment 4.90334367E8 -6.7E7 -1.04 4.90291962E8 -5.07E7 -1.15 -1.5479 -0.9989 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N22 compound treatment 5.14270476E8 -4.3E7 -0.67 4.85660537E8 -5.53E7 -1.25 -1.3583 -0.9573 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N23 compound treatment 4.93110558E8 -6.42E7 -1.0 4.898753E8 -5.11E7 -1.16 -1.524 -0.9974 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 N24 compound treatment 4.96838463E8 -6.05E7 -0.94 4.7871732E8 -6.23E7 -1.41 -1.6613 -0.9809 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O01 compound treatment 5.45683206E8 -1.16E7 -0.18 5.37857478E8 -3130000.0 -0.07 -0.1782 -0.9159 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O02 compound treatment 5.57690946E8 373000.0 0.01 5.42632598E8 1640000.0 0.04 0.0304 0.8078 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O03 compound treatment 5.2043416E8 -3.69E7 -0.57 5.380206E8 -2970000.0 -0.07 -0.4537 -0.7843 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O04 compound treatment 5.22561082E8 -3.48E7 -0.54 5.23117173E8 -1.79E7 -0.4 -0.6684 -0.9896 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O05 compound treatment 5.08610585E8 -4.87E7 -0.76 5.0485181E8 -3.61E7 -0.82 -1.114 -0.9993 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O06 compound treatment 5.65121094E8 7800000.0 0.12 5.52782875E8 1.18E7 0.27 0.2744 0.9367 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O07 compound treatment 5.29564169E8 -2.78E7 -0.43 5.3937681E8 -1610000.0 -0.04 -0.3314 -0.764 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O08 compound treatment 5.7956247E8 2.22E7 0.35 5.51434831E8 1.04E7 0.24 0.4119 0.9825 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O09 compound treatment 5.27970713E8 -2.93E7 -0.46 5.38122273E8 -2870000.0 -0.06 -0.369 -0.7993 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O10 compound treatment 5.30629726E8 -2.67E7 -0.42 5.07566302E8 -3.34E7 -0.76 -0.8281 -0.9604 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O11 mock treatment 5.41600941E8 -1.57E7 -0.24 5.64988592E8 2.4E7 0.54 0.2104 0.3536 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O12 mock treatment 5.45719861E8 -1.16E7 -0.18 5.45835426E8 4850000.0 0.11 -0.0503 -0.238 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O13 compound treatment 5.2152734E8 -3.58E7 -0.56 5.02715244E8 -3.83E7 -0.86 -1.0058 -0.9774 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O14 compound treatment 5.08185243E8 -4.91E7 -0.77 5.35144174E8 -5840000.0 -0.13 -0.6345 -0.8171 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O15 compound treatment 5.28301546E8 -2.9E7 -0.45 5.2261818E8 -1.84E7 -0.42 -0.6132 -0.9991 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O16 compound treatment 5.26239892E8 -3.11E7 -0.48 5.20034453E8 -2.1E7 -0.47 -0.6772 -0.9999 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O17 compound treatment 5.48709494E8 -8610000.0 -0.13 5.48915035E8 7930000.0 0.18 0.0319 0.1423 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O18 compound treatment 5.17457658E8 -3.99E7 -0.62 5.13112525E8 -2.79E7 -0.63 -0.8845 -1.0 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O19 compound treatment 5.21585043E8 -3.57E7 -0.56 5.2875006E8 -1.22E7 -0.28 -0.5891 -0.9479 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O20 compound treatment 5.08888229E8 -4.84E7 -0.75 5.08370917E8 -3.26E7 -0.74 -1.0547 -0.9999 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O21 compound treatment 5.34410162E8 -2.29E7 -0.36 5.39237448E8 -1750000.0 -0.04 -0.2803 -0.7807 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O22 compound treatment 5.29781303E8 -2.75E7 -0.43 5.24042644E8 -1.69E7 -0.38 -0.5741 -0.9984 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O23 compound treatment 5.28401517E8 -2.89E7 -0.45 5.05154543E8 -3.58E7 -0.81 -0.8911 -0.9617 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 O24 compound treatment 5.16998629E8 -4.03E7 -0.63 5.04258996E8 -3.67E7 -0.83 -1.031 -0.9905 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P01 compound treatment 5.47257343E8 -1.01E7 -0.16 5.42186188E8 1200000.0 0.03 -0.0917 -0.5765 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P02 compound treatment 5.70806406E8 1.35E7 0.21 5.30254834E8 -1.07E7 -0.24 -0.023 -0.0716 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P03 compound treatment 5.71840785E8 1.45E7 0.23 5.24291113E8 -1.67E7 -0.38 -0.1069 -0.2429 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P04 compound treatment 5.60778902E8 3460000.0 0.05 5.39564787E8 -1420000.0 -0.03 0.0154 0.2447 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P05 compound treatment 5.2799585E8 -2.93E7 -0.46 5.36884299E8 -4100000.0 -0.09 -0.3885 -0.8337 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P06 compound treatment 5.8023818E8 2.29E7 0.36 5.43979586E8 2990000.0 0.07 0.3002 0.8263 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P07 compound treatment 5.66397673E8 9080000.0 0.14 5.60286577E8 1.93E7 0.44 0.4084 0.8907 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P08 compound treatment 5.50333019E8 -6990000.0 -0.11 5.49702541E8 8710000.0 0.2 0.0623 0.277 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P09 compound treatment 5.15554064E8 -4.18E7 -0.65 5.4533401E8 4350000.0 0.1 -0.3905 -0.5936 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P10 compound treatment 5.37888155E8 -1.94E7 -0.3 5.26670016E8 -1.43E7 -0.32 -0.4428 -0.9994 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P11 mock treatment 5.5750027E8 182000.0 0.0 5.58348665E8 1.74E7 0.39 0.2794 0.7122 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P12 mock treatment 5.92785192E8 3.55E7 0.55 5.84326874E8 4.33E7 0.98 1.0832 0.9633 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P13 compound treatment 5.52414577E8 -4900000.0 -0.08 5.34264477E8 -6720000.0 -0.15 -0.1615 -0.9493 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P14 compound treatment 5.68788187E8 1.15E7 0.18 5.24233253E8 -1.68E7 -0.38 -0.1414 -0.3378 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P15 compound treatment 5.55062823E8 -2260000.0 -0.04 5.30595808E8 -1.04E7 -0.23 -0.1909 -0.8039 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P16 compound treatment 5.66842234E8 9520000.0 0.15 5.52034122E8 1.1E7 0.25 0.2814 0.9691 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P17 compound treatment 5.57066905E8 -251000.0 0.0 5.48398365E8 7410000.0 0.17 0.1156 0.6904 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P18 compound treatment 5.73019039E8 1.57E7 0.24 5.36514091E8 -4470000.0 -0.1 0.1014 0.3832 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P19 compound treatment 5.52055626E8 -5260000.0 -0.08 5.21224039E8 -1.98E7 -0.45 -0.3738 -0.8231 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P20 compound treatment 5.51840583E8 -5480000.0 -0.09 5.16488924E8 -2.45E7 -0.55 -0.4519 -0.8065 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P21 compound treatment 5.44900228E8 -1.24E7 -0.19 4.96920791E8 -4.41E7 -1.0 -0.841 -0.8289 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P22 compound treatment 5.43519156E8 -1.38E7 -0.21 5.19767802E8 -2.12E7 -0.48 -0.4911 -0.9345 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P23 compound treatment 5.41039884E8 -1.63E7 -0.25 5.33425688E8 -7560000.0 -0.17 -0.3002 -0.9816 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2102 P24 compound treatment 5.54042495E8 -3280000.0 -0.05 5.40120122E8 -869000.0 -0.02 -0.05 -0.9138 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A01 compound treatment 5.40724025E8 -1.41E7 -0.22 5.20828149E8 -1.16E7 -0.26 -0.3409 -0.996 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A02 compound treatment 5.75765782E8 2.1E7 0.33 5.4210273E8 9660000.0 0.22 0.3851 0.9809 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A03 compound treatment 5.87524762E8 3.27E7 0.51 5.4415822E8 1.17E7 0.26 0.5474 0.9535 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A04 compound treatment 5.69920027E8 1.51E7 0.24 5.54509141E8 2.21E7 0.5 0.519 0.9413 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A05 compound treatment 5.5782486E8 3010000.0 0.05 5.12528947E8 -1.99E7 -0.45 -0.2851 -0.63 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A06 compound treatment 5.56047567E8 1230000.0 0.02 5.06645257E8 -2.58E7 -0.58 -0.3987 -0.6834 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A07 compound treatment 5.54488775E8 -325000.0 -0.01 4.93579572E8 -3.89E7 -0.88 -0.6247 -0.7112 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A08 compound treatment 5.62662564E8 7850000.0 0.12 4.98682626E8 -3.38E7 -0.76 -0.4531 -0.5863 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A09 compound treatment 5.34720321E8 -2.01E7 -0.31 4.96001667E8 -3.64E7 -0.82 -0.8037 -0.9122 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A10 compound treatment 5.38500791E8 -1.63E7 -0.25 4.95307592E8 -3.71E7 -0.84 -0.7732 -0.8817 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A11 compound treatment 5.56948158E8 2130000.0 0.03 4.76192766E8 -5.63E7 -1.27 -0.8755 -0.6884 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A12 compound treatment 5.52719841E8 -2090000.0 -0.03 5.05062569E8 -2.74E7 -0.62 -0.4607 -0.7433 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A13 mock treatment 5.46414377E8 -8400000.0 -0.13 5.46639248E8 1.42E7 0.32 0.1343 0.3877 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A14 mock treatment 5.55730874E8 917000.0 0.01 5.04944873E8 -2.75E7 -0.62 -0.4294 -0.6907 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A15 compound treatment 5.03971426E8 -5.08E7 -0.79 4.88595845E8 -4.39E7 -0.99 -1.2607 -0.9938 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A16 compound treatment 5.29945372E8 -2.49E7 -0.39 5.0033E8 -3.21E7 -0.73 -0.7871 -0.9567 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A17 compound treatment 5.04357833E8 -5.05E7 -0.79 4.89084255E8 -4.34E7 -0.98 -1.2487 -0.994 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A18 compound treatment 5.13067186E8 -4.17E7 -0.65 5.13557307E8 -1.89E7 -0.43 -0.7617 -0.9792 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A19 compound treatment 5.05034003E8 -4.98E7 -0.78 4.74614695E8 -5.78E7 -1.31 -1.4725 -0.9689 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A20 compound treatment 5.38785778E8 -1.6E7 -0.25 5.17400841E8 -1.5E7 -0.34 -0.417 -0.9885 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A21 compound treatment 4.82614254E8 -7.22E7 -1.12 4.70218986E8 -6.22E7 -1.41 -1.7896 -0.9939 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A22 compound treatment 5.23255768E8 -3.16E7 -0.49 5.06900302E8 -2.55E7 -0.58 -0.7558 -0.9968 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A23 compound treatment 4.87747906E8 -6.71E7 -1.04 4.70585388E8 -6.19E7 -1.4 -1.7272 -0.9897 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 A24 compound treatment 5.18107447E8 -3.67E7 -0.57 5.04684447E8 -2.78E7 -0.63 -0.8479 -0.9989 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B01 compound treatment 3.9369284E8 -1.61E8 -2.51 4.02986047E8 -1.29E8 -2.93 -3.8434 -0.9971 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B02 compound treatment 5.07716196E8 -4.71E7 -0.73 5.07112063E8 -2.53E7 -0.57 -0.9236 -0.9925 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B03 compound treatment 5.0190861E8 -5.29E7 -0.82 5.11422785E8 -2.1E7 -0.48 -0.9187 -0.9658 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B04 compound treatment 5.02390562E8 -5.24E7 -0.82 5.05883711E8 -2.66E7 -0.6 -1.0019 -0.9886 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B05 compound treatment 4.73681989E8 -8.11E7 -1.26 4.97943985E8 -3.45E7 -0.78 -1.445 -0.9731 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B06 compound treatment 5.22623537E8 -3.22E7 -0.5 5.19184699E8 -1.33E7 -0.3 -0.5665 -0.9697 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B07 compound treatment 5.0554221E8 -4.93E7 -0.77 4.65939139E8 -6.65E7 -1.5 -1.6055 -0.9513 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B08 compound treatment 5.55726433E8 913000.0 0.01 5.34859016E8 2410000.0 0.05 0.0486 0.8627 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B09 compound treatment 5.10968094E8 -4.38E7 -0.68 4.34790917E8 -9.77E7 -2.21 -2.0435 -0.8845 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B10 compound treatment 5.55840725E8 1030000.0 0.02 4.87433112E8 -4.5E7 -1.02 -0.708 -0.6959 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B11 compound treatment 4.84277353E8 -7.05E7 -1.1 4.51515062E8 -8.09E7 -1.83 -2.0702 -0.9703 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B12 compound treatment 5.32256205E8 -2.26E7 -0.35 4.83380519E8 -4.91E7 -1.11 -1.0326 -0.8877 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B13 mock treatment 5.50876012E8 -3940000.0 -0.06 5.01989907E8 -3.05E7 -0.69 -0.5301 -0.7671 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B14 mock treatment 5.21527935E8 -3.33E7 -0.52 4.97794103E8 -3.47E7 -0.78 -0.9204 -0.9799 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B15 compound treatment 5.29392815E8 -2.54E7 -0.4 5.13478172E8 -1.9E7 -0.43 -0.5831 -0.9992 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B16 compound treatment 4.87940414E8 -6.69E7 -1.04 4.76067165E8 -5.64E7 -1.27 -1.6375 -0.995 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B17 compound treatment 5.01737309E8 -5.31E7 -0.83 4.79797074E8 -5.26E7 -1.19 -1.426 -0.9842 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B18 compound treatment 4.90650514E8 -6.42E7 -1.0 4.8911214E8 -4.33E7 -0.98 -1.3992 -0.9999 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B19 compound treatment 4.87650951E8 -6.72E7 -1.05 4.78605273E8 -5.38E7 -1.22 -1.6001 -0.9972 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B20 compound treatment 5.32720518E8 -2.21E7 -0.34 5.23150012E8 -9300000.0 -0.21 -0.3919 -0.972 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B21 compound treatment 4.64986138E8 -8.98E7 -1.4 4.48794911E8 -8.37E7 -1.89 -2.3262 -0.989 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B22 compound treatment 5.04135948E8 -5.07E7 -0.79 4.84500009E8 -4.79E7 -1.08 -1.3244 -0.9879 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B23 compound treatment 4.72021299E8 -8.28E7 -1.29 4.69172823E8 -6.33E7 -1.43 -1.923 -0.9987 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 B24 compound treatment 4.93783064E8 -6.1E7 -0.95 4.67938091E8 -6.45E7 -1.46 -1.7031 -0.9785 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C01 compound treatment 5.63565588E8 8750000.0 0.14 5.37992286E8 5550000.0 0.13 0.185 0.9991 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C02 compound treatment 5.89894932E8 3.51E7 0.55 5.24974316E8 -7470000.0 -0.17 0.267 0.4668 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C03 compound treatment 5.99876525E8 4.51E7 0.7 5.89004807E8 5.66E7 1.28 1.4002 0.9602 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C04 compound treatment 6.02613631E8 4.78E7 0.74 5.52577901E8 2.01E7 0.45 0.8482 0.9721 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C05 compound treatment 5.95302574E8 4.05E7 0.63 5.27598523E8 -4850000.0 -0.11 0.3685 0.5756 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C06 compound treatment 6.1208373E8 5.73E7 0.89 5.6310684E8 3.07E7 0.69 1.1207 0.9922 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C07 compound treatment 5.91116427E8 3.63E7 0.57 5.52178756E8 1.97E7 0.45 0.7152 0.9931 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C08 compound treatment 5.79936675E8 2.51E7 0.39 5.66603816E8 3.42E7 0.77 0.8226 0.9504 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C09 compound treatment 5.6813568E8 1.33E7 0.21 5.31033615E8 -1410000.0 -0.03 0.1241 0.5913 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C10 compound treatment 5.8505016E8 3.02E7 0.47 5.58502842E8 2.61E7 0.59 0.7494 0.9939 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C11 mock treatment 5.86471086E8 3.17E7 0.49 5.54278671E8 2.18E7 0.49 0.6976 1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C12 mock treatment 5.88991011E8 3.42E7 0.53 5.83644315E8 5.12E7 1.16 1.1946 0.9379 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C13 compound treatment 5.90348513E8 3.55E7 0.55 5.3817E8 5720000.0 0.13 0.4828 0.8495 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C14 compound treatment 5.38548416E8 -1.63E7 -0.25 5.07327863E8 -2.51E7 -0.57 -0.5806 -0.9339 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C15 mock treatment 5.95994858E8 4.12E7 0.64 5.63703533E8 3.13E7 0.71 0.9531 0.9988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C16 mock treatment 5.95718688E8 4.09E7 0.64 5.79366783E8 4.69E7 1.06 1.2003 0.9703 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C17 compound treatment 5.57632484E8 2820000.0 0.04 5.45950879E8 1.35E7 0.31 0.2469 0.8006 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C18 compound treatment 5.38417929E8 -1.64E7 -0.26 5.23031653E8 -9420000.0 -0.21 -0.331 -0.9959 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C19 compound treatment 5.61837943E8 7020000.0 0.11 5.39057044E8 6610000.0 0.15 0.183 0.9883 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C20 compound treatment 5.81286063E8 2.65E7 0.41 5.47451905E8 1.5E7 0.34 0.5314 0.9953 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C21 compound treatment 5.52255346E8 -2560000.0 -0.04 5.18981946E8 -1.35E7 -0.3 -0.2434 -0.7929 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C22 compound treatment 5.67309571E8 1.25E7 0.19 5.53103238E8 2.07E7 0.47 0.4677 0.9248 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C23 compound treatment 5.52625264E8 -2190000.0 -0.03 5.50349007E8 1.79E7 0.4 0.262 0.6453 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 C24 compound treatment 5.8122499E8 2.64E7 0.41 5.57762345E8 2.53E7 0.57 0.6955 0.9869 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D01 compound treatment 5.44256685E8 -1.06E7 -0.16 5.06439674E8 -2.6E7 -0.59 -0.5319 -0.8715 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D02 compound treatment 5.27073372E8 -2.77E7 -0.43 4.97591334E8 -3.49E7 -0.79 -0.8625 -0.96 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D03 compound treatment 5.97629513E8 4.28E7 0.67 5.42034027E8 9590000.0 0.22 0.6248 0.891 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D04 compound treatment 5.70848788E8 1.6E7 0.25 5.21151319E8 -1.13E7 -0.26 -0.0039 -0.0109 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D05 compound treatment 5.53842588E8 -971000.0 -0.02 5.07442271E8 -2.5E7 -0.57 -0.4103 -0.7258 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D06 compound treatment 5.51372737E8 -3440000.0 -0.05 5.2269743E8 -9750000.0 -0.22 -0.1937 -0.8542 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D07 compound treatment 5.7201555E8 1.72E7 0.27 4.88479168E8 -4.4E7 -0.99 -0.5132 -0.4986 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D08 compound treatment 6.08002618E8 5.32E7 0.83 5.78764932E8 4.63E7 1.05 1.326 0.9933 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D09 compound treatment 5.62921286E8 8110000.0 0.13 5.3266308E8 216000.0 0.0 0.0928 0.7339 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D10 compound treatment 5.77588071E8 2.28E7 0.35 5.37820667E8 5370000.0 0.12 0.3367 0.898 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D11 mock treatment 5.85749089E8 3.09E7 0.48 5.57775548E8 2.53E7 0.57 0.7455 0.9963 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D12 mock treatment 5.75408954E8 2.06E7 0.32 5.60092912E8 2.76E7 0.62 0.6686 0.952 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D13 compound treatment 5.83891077E8 2.91E7 0.45 5.60811079E8 2.84E7 0.64 0.7735 0.9855 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D14 compound treatment 5.79242815E8 2.44E7 0.38 5.17831461E8 -1.46E7 -0.33 0.0355 0.0705 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D15 mock treatment 5.83337679E8 2.85E7 0.44 5.63046482E8 3.06E7 0.69 0.8032 0.9771 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D16 mock treatment 5.91709058E8 3.69E7 0.57 5.60439888E8 2.8E7 0.63 0.8537 0.9988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D17 compound treatment 5.38202135E8 -1.66E7 -0.26 5.29803204E8 -2640000.0 -0.06 -0.2252 -0.8481 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D18 compound treatment 5.59547834E8 4730000.0 0.07 5.36908162E8 4460000.0 0.1 0.1234 0.9882 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D19 compound treatment 5.47983704E8 -6830000.0 -0.11 5.41392759E8 8950000.0 0.2 0.0677 0.2965 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D20 compound treatment 5.79293064E8 2.45E7 0.38 5.30243806E8 -2200000.0 -0.05 0.2344 0.6096 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D21 compound treatment 5.53944589E8 -869000.0 -0.01 5.18710917E8 -1.37E7 -0.31 -0.2291 -0.7372 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D22 compound treatment 5.562894E8 1480000.0 0.02 5.39900659E8 7450000.0 0.17 0.1354 0.7962 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D23 compound treatment 5.14365971E8 -4.04E7 -0.63 4.97627612E8 -3.48E7 -0.79 -1.0019 -0.9939 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 D24 compound treatment 5.54600135E8 -213000.0 0.0 5.19866733E8 -1.26E7 -0.28 -0.2034 -0.7153 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E01 mock treatment 5.75209789E8 2.04E7 0.32 4.96136989E8 -3.63E7 -0.82 -0.3556 -0.4041 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E02 mock treatment 5.51187796E8 -3630000.0 -0.06 5.08917649E8 -2.35E7 -0.53 -0.4159 -0.7778 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E03 compound treatment 5.24568285E8 -3.02E7 -0.47 4.73634055E8 -5.88E7 -1.33 -1.273 -0.9027 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E04 compound treatment 5.41997387E8 -1.28E7 -0.2 4.87930786E8 -4.45E7 -1.01 -0.8526 -0.8312 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E05 compound treatment 5.07147958E8 -4.77E7 -0.74 4.68189976E8 -6.43E7 -1.45 -1.5518 -0.9515 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E06 compound treatment 5.1921907E8 -3.56E7 -0.55 5.00420705E8 -3.2E7 -0.72 -0.9038 -0.9913 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E07 compound treatment 5.20896526E8 -3.39E7 -0.53 4.98158499E8 -3.43E7 -0.77 -0.9215 -0.9826 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E08 compound treatment 5.18747928E8 -3.61E7 -0.56 4.95699955E8 -3.67E7 -0.83 -0.9845 -0.9819 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E09 mock treatment 5.28702304E8 -2.61E7 -0.41 5.23165101E8 -9280000.0 -0.21 -0.4359 -0.9526 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E10 mock treatment 5.4131846E8 -1.35E7 -0.21 5.23686731E8 -8760000.0 -0.2 -0.2886 -0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E11 compound treatment 5.29446207E8 -2.54E7 -0.4 4.85370706E8 -4.71E7 -1.06 -1.0317 -0.909 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E12 compound treatment 5.3716804E8 -1.76E7 -0.27 5.10410613E8 -2.2E7 -0.5 -0.5465 -0.9607 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E13 compound treatment 4.96053103E8 -5.88E7 -0.92 4.82521474E8 -4.99E7 -1.13 -1.445 -0.9946 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E14 compound treatment 5.25577881E8 -2.92E7 -0.46 5.13661879E8 -1.88E7 -0.42 -0.6222 -0.9994 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E15 compound treatment 5.02594863E8 -5.22E7 -0.81 4.85706068E8 -4.67E7 -1.06 -1.3221 -0.9917 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E16 compound treatment 5.19366255E8 -3.54E7 -0.55 4.9231448E8 -4.01E7 -0.91 -1.0318 -0.9717 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E17 mock treatment 5.23403566E8 -3.14E7 -0.49 5.06968726E8 -2.55E7 -0.58 -0.7531 -0.9967 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E18 mock treatment 5.18092513E8 -3.67E7 -0.57 5.04895285E8 -2.76E7 -0.62 -0.8447 -0.9991 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E19 compound treatment 5.06923245E8 -4.79E7 -0.75 4.8384868E8 -4.86E7 -1.1 -1.3041 -0.9822 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E20 compound treatment 5.11742882E8 -4.31E7 -0.67 5.27796256E8 -4650000.0 -0.11 -0.5487 -0.808 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E21 compound treatment 4.98117014E8 -5.67E7 -0.88 4.71122823E8 -6.13E7 -1.39 -1.6044 -0.9763 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E22 compound treatment 5.22134873E8 -3.27E7 -0.51 5.00072624E8 -3.24E7 -0.73 -0.8773 -0.9843 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E23 compound treatment 4.85903632E8 -6.89E7 -1.07 4.55022747E8 -7.74E7 -1.75 -1.9963 -0.9725 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 E24 compound treatment 4.98735167E8 -5.61E7 -0.87 4.82909212E8 -4.95E7 -1.12 -1.4093 -0.9925 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F01 mock treatment 5.26250238E8 -2.86E7 -0.44 5.19773175E8 -1.27E7 -0.29 -0.5171 -0.9773 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F02 mock treatment 5.3426208E8 -2.06E7 -0.32 5.3429349E8 1850000.0 0.04 -0.1968 -0.6098 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F03 compound treatment 5.4569369E8 -9120000.0 -0.14 5.52823337E8 2.04E7 0.46 0.2252 0.4673 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F04 compound treatment 5.26153135E8 -2.87E7 -0.45 5.28517257E8 -3930000.0 -0.09 -0.3785 -0.8315 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F05 compound treatment 5.13721836E8 -4.11E7 -0.64 4.84863823E8 -4.76E7 -1.08 -1.213 -0.9693 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F06 compound treatment 5.44575826E8 -1.02E7 -0.16 5.2553172E8 -6920000.0 -0.16 -0.2233 -0.9999 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F07 compound treatment 5.06756518E8 -4.81E7 -0.75 4.80889194E8 -5.16E7 -1.17 -1.3532 -0.9771 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F08 compound treatment 5.2779436E8 -2.7E7 -0.42 5.07172743E8 -2.53E7 -0.57 -0.7015 -0.9887 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F09 mock treatment 5.60160213E8 5350000.0 0.08 5.26958471E8 -5490000.0 -0.12 -0.0288 -0.1929 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F10 mock treatment 5.55927052E8 1110000.0 0.02 5.02532149E8 -2.99E7 -0.68 -0.4658 -0.6887 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F11 compound treatment 5.43769612E8 -1.1E7 -0.17 5.23011051E8 -9440000.0 -0.21 -0.2724 -0.9943 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F12 compound treatment 5.45225598E8 -9590000.0 -0.15 4.9432782E8 -3.81E7 -0.86 -0.7148 -0.8175 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F13 compound treatment 5.20371329E8 -3.44E7 -0.54 4.91663496E8 -4.08E7 -0.92 -1.0311 -0.9668 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F14 compound treatment 5.25819E8 -2.9E7 -0.45 4.85330383E8 -4.71E7 -1.06 -1.0723 -0.9271 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F15 compound treatment 5.34091367E8 -2.07E7 -0.32 5.1373714E8 -1.87E7 -0.42 -0.5272 -0.9911 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F16 compound treatment 5.14115748E8 -4.07E7 -0.63 4.85255129E8 -4.72E7 -1.07 -1.2024 -0.9691 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F17 mock treatment 5.50139169E8 -4670000.0 -0.07 5.24131208E8 -8320000.0 -0.19 -0.1844 -0.9148 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F18 mock treatment 5.44385237E8 -1.04E7 -0.16 5.1603908E8 -1.64E7 -0.37 -0.3771 -0.9314 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F19 compound treatment 5.64506158E8 9690000.0 0.15 5.12480865E8 -2.0E7 -0.45 -0.2123 -0.4462 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F20 compound treatment 5.07666964E8 -4.71E7 -0.73 4.5823121E8 -7.42E7 -1.68 -1.7053 -0.9313 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F21 compound treatment 4.97413334E8 -5.74E7 -0.89 4.75282853E8 -5.72E7 -1.29 -1.5457 -0.9838 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F22 compound treatment 5.22273017E8 -3.25E7 -0.51 4.80429663E8 -5.2E7 -1.18 -1.1897 -0.9293 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F23 compound treatment 4.96344711E8 -5.85E7 -0.91 4.77472248E8 -5.5E7 -1.24 -1.5225 -0.9883 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 F24 compound treatment 5.05417249E8 -4.94E7 -0.77 5.02307719E8 -3.01E7 -0.68 -1.0257 -0.9982 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G01 compound treatment 5.58712581E8 3900000.0 0.06 5.3422125E8 1770000.0 0.04 0.0713 0.9797 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G02 compound treatment 5.67053709E8 1.22E7 0.19 5.23352165E8 -9090000.0 -0.21 -0.0105 -0.0375 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G03 mock treatment 5.77559582E8 2.27E7 0.35 5.41166332E8 8720000.0 0.2 0.3899 0.9617 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G04 mock treatment 5.97566884E8 4.28E7 0.67 5.73478952E8 4.1E7 0.93 1.1266 0.9868 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G05 compound treatment 5.70622958E8 1.58E7 0.25 5.51932088E8 1.95E7 0.44 0.4855 0.9623 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G06 compound treatment 5.99760746E8 4.49E7 0.7 5.36957463E8 4510000.0 0.1 0.5671 0.8016 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G07 compound treatment 5.77702742E8 2.29E7 0.36 5.13009399E8 -1.94E7 -0.44 -0.0585 -0.1034 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G08 compound treatment 5.47895595E8 -6920000.0 -0.11 5.40918923E8 8470000.0 0.19 0.0592 0.2694 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G09 compound treatment 5.55460717E8 647000.0 0.01 5.31874209E8 -573000.0 -0.01 -0.002 -0.1233 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G10 compound treatment 5.53553902E8 -1260000.0 -0.02 5.47316661E8 1.49E7 0.34 0.2238 0.6647 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G11 compound treatment 5.72743654E8 1.79E7 0.28 5.40449624E8 8000000.0 0.18 0.3254 0.9779 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G12 compound treatment 5.39528023E8 -1.53E7 -0.24 5.32663561E8 217000.0 0.0 -0.1649 -0.6924 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G13 compound treatment 5.51540016E8 -3270000.0 -0.05 5.42596468E8 1.01E7 0.23 0.1261 0.5368 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G14 compound treatment 5.82997807E8 2.82E7 0.44 5.49125188E8 1.67E7 0.38 0.577 0.9971 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G15 compound treatment 5.84891454E8 3.01E7 0.47 5.34313016E8 1870000.0 0.04 0.3611 0.7677 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G16 compound treatment 5.68889319E8 1.41E7 0.22 5.34301677E8 1850000.0 0.04 0.1847 0.8273 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G17 compound treatment 5.52599073E8 -2210000.0 -0.03 5.32359469E8 -87300.0 0.0 -0.0258 -0.7463 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G18 compound treatment 5.84750214E8 2.99E7 0.47 5.2662674E8 -5820000.0 -0.13 0.2367 0.4886 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G19 mock treatment 5.66941385E8 1.21E7 0.19 5.43407332E8 1.1E7 0.25 0.3087 0.9911 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G20 mock treatment 5.95945228E8 4.11E7 0.64 5.30902896E8 -1540000.0 -0.03 0.4283 0.6676 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G21 compound treatment 5.48661503E8 -6150000.0 -0.1 5.21106277E8 -1.13E7 -0.26 -0.249 -0.91 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G22 compound treatment 5.86851989E8 3.2E7 0.5 5.39920687E8 7470000.0 0.17 0.4723 0.8965 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G23 compound treatment 5.3730955E8 -1.75E7 -0.27 5.19702828E8 -1.27E7 -0.29 -0.3964 -0.9996 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 G24 compound treatment 5.54809486E8 -4020.0 0.0 5.15157602E8 -1.73E7 -0.39 -0.2763 -0.7072 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H01 compound treatment 5.73955512E8 1.91E7 0.3 5.73142222E8 4.07E7 0.92 0.8612 0.8907 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H02 compound treatment 5.37578646E8 -1.72E7 -0.27 5.08455101E8 -2.4E7 -0.54 -0.5732 -0.9474 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H03 mock treatment 5.57907014E8 3090000.0 0.05 5.47739764E8 1.53E7 0.35 0.2785 0.798 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H04 mock treatment 5.87983559E8 3.32E7 0.52 5.71467859E8 3.9E7 0.88 0.9889 0.9676 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H05 compound treatment 5.1658899E8 -3.82E7 -0.6 5.03939468E8 -2.85E7 -0.64 -0.8766 -0.9992 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H06 compound treatment 5.718195E8 1.7E7 0.26 4.77731788E8 -5.47E7 -1.24 -0.6871 -0.5433 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H07 compound treatment 5.49136457E8 -5680000.0 -0.09 5.52706729E8 2.03E7 0.46 0.2612 0.5602 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H08 compound treatment 5.89437986E8 3.46E7 0.54 5.42793328E8 1.03E7 0.23 0.5467 0.93 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H09 compound treatment 5.90270386E8 3.55E7 0.55 5.43077088E8 1.06E7 0.24 0.5604 0.9305 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H10 compound treatment 5.67147591E8 1.23E7 0.19 5.37314783E8 4870000.0 0.11 0.2136 0.965 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H11 compound treatment 5.74845725E8 2.0E7 0.31 5.61272274E8 2.88E7 0.65 0.6813 0.9432 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H12 compound treatment 5.40776749E8 -1.4E7 -0.22 5.50483069E8 1.8E7 0.41 0.1336 0.2889 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H13 compound treatment 5.75277736E8 2.05E7 0.32 5.66786954E8 3.43E7 0.78 0.7742 0.9227 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H14 compound treatment 5.67531864E8 1.27E7 0.2 5.23938913E8 -8510000.0 -0.19 0.0041 0.0149 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H15 compound treatment 5.72481356E8 1.77E7 0.28 5.64405332E8 3.2E7 0.72 0.7053 0.9125 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H16 compound treatment 5.62350561E8 7540000.0 0.12 5.45255445E8 1.28E7 0.29 0.2877 0.921 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H17 compound treatment 5.77100282E8 2.23E7 0.35 5.49792955E8 1.73E7 0.39 0.5227 0.9982 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H18 compound treatment 5.77814471E8 2.3E7 0.36 5.43352357E8 1.09E7 0.25 0.4276 0.9833 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H19 mock treatment 5.73275854E8 1.85E7 0.29 5.56849556E8 2.44E7 0.55 0.5933 0.9539 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H20 mock treatment 5.71978599E8 1.72E7 0.27 5.43645382E8 1.12E7 0.25 0.368 0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H21 compound treatment 5.01120547E8 -5.37E7 -0.84 4.6535059E8 -6.71E7 -1.52 -1.6636 -0.9607 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H22 compound treatment 5.53317478E8 -1500000.0 -0.02 5.41258501E8 8810000.0 0.2 0.1243 0.6201 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H23 compound treatment 5.14269085E8 -4.05E7 -0.63 5.02962922E8 -2.95E7 -0.67 -0.9177 -0.9996 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 H24 compound treatment 5.4389797E8 -1.09E7 -0.17 5.37902649E8 5460000.0 0.12 -0.033 -0.1573 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I01 compound treatment 4.51310761E8 -1.04E8 -1.61 4.89527251E8 -4.29E7 -0.97 -1.8259 -0.9704 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I02 compound treatment 5.33197613E8 -2.16E7 -0.34 4.7728198E8 -5.52E7 -1.25 -1.1196 -0.867 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I03 compound treatment 4.72849525E8 -8.2E7 -1.28 4.59613765E8 -7.28E7 -1.65 -2.0667 -0.9921 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I04 compound treatment 5.25887409E8 -2.89E7 -0.45 5.11918781E8 -2.05E7 -0.46 -0.6466 -0.9999 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I05 mock treatment 5.29801991E8 -2.5E7 -0.39 4.92149743E8 -4.03E7 -0.91 -0.9194 -0.9282 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I06 mock treatment 5.35587632E8 -1.92E7 -0.3 4.91815304E8 -4.06E7 -0.92 -0.8611 -0.8915 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I07 compound treatment 4.91741136E8 -6.31E7 -0.98 4.46175443E8 -8.63E7 -1.95 -2.0733 -0.9497 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I08 compound treatment 5.22934651E8 -3.19E7 -0.5 4.98310232E8 -3.41E7 -0.77 -0.8966 -0.9773 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I09 compound treatment 4.85153816E8 -6.97E7 -1.09 4.82262458E8 -5.02E7 -1.13 -1.5692 -0.9998 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I10 compound treatment 4.98438621E8 -5.64E7 -0.88 5.11874764E8 -2.06E7 -0.46 -0.9497 -0.9558 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I11 compound treatment 5.25714042E8 -2.91E7 -0.45 4.90550783E8 -4.19E7 -0.95 -0.99 -0.9431 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I12 compound treatment 5.06074435E8 -4.87E7 -0.76 5.06294961E8 -2.62E7 -0.59 -0.9547 -0.9923 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I13 compound treatment 5.34157758E8 -2.07E7 -0.32 4.7539137E8 -5.71E7 -1.29 -1.1393 -0.8573 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I14 compound treatment 5.24658627E8 -3.02E7 -0.47 5.16658308E8 -1.58E7 -0.36 -0.5844 -0.9908 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I15 compound treatment 5.25110234E8 -2.97E7 -0.46 5.20817575E8 -1.16E7 -0.26 -0.513 -0.9641 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I16 compound treatment 4.92784187E8 -6.2E7 -0.97 4.778628E8 -5.46E7 -1.23 -1.5555 -0.9927 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I17 compound treatment 5.31944231E8 -2.29E7 -0.36 4.96610797E8 -3.58E7 -0.81 -0.8246 -0.932 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I18 compound treatment 5.15139831E8 -3.97E7 -0.62 4.67458864E8 -6.5E7 -1.47 -1.4755 -0.926 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I19 compound treatment 4.54718715E8 -1.0E8 -1.56 4.82490159E8 -5.0E7 -1.13 -1.9008 -0.9874 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I20 compound treatment 5.29565324E8 -2.52E7 -0.39 4.90271212E8 -4.22E7 -0.95 -0.9521 -0.9233 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I21 mock treatment 5.20348754E8 -3.45E7 -0.54 5.02815815E8 -2.96E7 -0.67 -0.8531 -0.994 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I22 mock treatment 5.27109128E8 -2.77E7 -0.43 4.9784098E8 -3.46E7 -0.78 -0.8582 -0.9607 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I23 compound treatment 4.88820742E8 -6.6E7 -1.03 4.84714565E8 -4.77E7 -1.08 -1.4896 -0.9997 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 I24 compound treatment 4.69103771E8 -8.57E7 -1.34 4.69645674E8 -6.28E7 -1.42 -1.9476 -0.9995 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J01 compound treatment 5.08203026E8 -4.66E7 -0.73 5.27665533E8 -4780000.0 -0.11 -0.5898 -0.8035 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J02 compound treatment 4.64082394E8 -9.07E7 -1.41 4.71052646E8 -6.14E7 -1.39 -1.9804 -1.0 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J03 compound treatment 5.71551861E8 1.67E7 0.26 5.36238409E8 3790000.0 0.09 0.2449 0.8925 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J04 compound treatment 4.50170945E8 -1.05E8 -1.63 4.36690926E8 -9.58E7 -2.16 -2.6828 -0.9902 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J05 mock treatment 5.23346034E8 -3.15E7 -0.49 5.24347713E8 -8100000.0 -0.18 -0.476 -0.9098 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J06 mock treatment 5.08364E8 -4.64E7 -0.72 5.37186893E8 4740000.0 0.11 -0.4358 -0.5959 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J07 compound treatment 4.5886909E8 -9.59E7 -1.49 5.27143155E8 -5300000.0 -0.12 -1.1415 -0.7614 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J08 compound treatment 4.62514584E8 -9.23E7 -1.44 5.28318113E8 -4130000.0 -0.09 -1.0825 -0.7514 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J09 compound treatment 4.95930085E8 -5.89E7 -0.92 5.29393248E8 -3050000.0 -0.07 -0.6973 -0.7582 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J10 compound treatment 4.3873867E8 -1.16E8 -1.81 4.63067565E8 -6.94E7 -1.57 -2.3872 -0.9975 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J11 compound treatment 5.32244672E8 -2.26E7 -0.35 5.04554824E8 -2.79E7 -0.63 -0.6943 -0.962 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J12 compound treatment 4.36125219E8 -1.19E8 -1.85 4.73622952E8 -5.88E7 -1.33 -2.2473 -0.9869 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J13 compound treatment 4.79364895E8 -7.54E7 -1.18 4.94153671E8 -3.83E7 -0.87 -1.4429 -0.9887 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J14 compound treatment 4.61612018E8 -9.32E7 -1.45 4.83349079E8 -4.91E7 -1.11 -1.8111 -0.9912 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J15 compound treatment 5.23091021E8 -3.17E7 -0.49 5.24674667E8 -7770000.0 -0.18 -0.4736 -0.9031 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J16 compound treatment 4.62371739E8 -9.24E7 -1.44 4.85604505E8 -4.68E7 -1.06 -1.7667 -0.9886 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J17 compound treatment 5.22090635E8 -3.27E7 -0.51 5.29295042E8 -3150000.0 -0.07 -0.4108 -0.7982 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J18 compound treatment 4.54611007E8 -1.0E8 -1.56 4.86529935E8 -4.59E7 -1.04 -1.8374 -0.9803 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J19 compound treatment 5.21215761E8 -3.36E7 -0.52 5.28256666E8 -4190000.0 -0.09 -0.437 -0.8217 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J20 compound treatment 4.44459819E8 -1.1E8 -1.72 4.88923905E8 -4.35E7 -0.98 -1.9109 -0.9649 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J21 mock treatment 5.38188133E8 -1.66E7 -0.26 5.32671815E8 225000.0 0.01 -0.1795 -0.6931 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J22 mock treatment 5.21053926E8 -3.38E7 -0.53 5.09682925E8 -2.28E7 -0.51 -0.7356 -0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J23 compound treatment 4.81022085E8 -7.38E7 -1.15 4.72009455E8 -6.04E7 -1.37 -1.7786 -0.9963 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 J24 compound treatment 4.40935177E8 -1.14E8 -1.77 4.29044508E8 -1.03E8 -2.34 -2.9067 -0.9907 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K01 compound treatment 5.04401316E8 -5.04E7 -0.79 4.36565847E8 -9.59E7 -2.17 -2.0875 -0.9057 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K02 compound treatment 5.40011827E8 -1.48E7 -0.23 4.85159593E8 -4.73E7 -1.07 -0.9187 -0.8403 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K03 compound treatment 3.03011233E8 -2.52E8 -3.92 3.82289582E8 -1.5E8 -3.39 -5.1729 -0.9974 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K04 compound treatment 5.45903608E8 -8910000.0 -0.14 5.14364913E8 -1.81E7 -0.41 -0.3871 -0.8969 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K05 compound treatment 2.89081804E8 -2.66E8 -4.14 3.15322091E8 -2.17E8 -4.91 -6.3965 -0.9964 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K06 compound treatment 5.40004523E8 -1.48E7 -0.23 4.88864488E8 -4.36E7 -0.98 -0.8596 -0.8497 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K07 mock treatment 5.56767887E8 1950000.0 0.03 5.30472665E8 -1970000.0 -0.04 -0.01 -0.1856 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K08 mock treatment 5.68182666E8 1.34E7 0.21 5.22618792E8 -9830000.0 -0.22 -0.0098 -0.0322 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K09 compound treatment 3.53784792E8 -2.01E8 -3.13 3.26681291E8 -2.06E8 -4.65 -5.5024 -0.9815 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K10 compound treatment 4.88558039E8 -6.63E7 -1.03 4.74035348E8 -5.84E7 -1.32 -1.6632 -0.9926 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K11 compound treatment 1.19272819E8 -4.36E8 -6.78 1.35876212E8 -3.97E8 -8.96 -11.1345 -0.9906 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K12 compound treatment 5.27666489E8 -2.71E7 -0.42 5.14591038E8 -1.79E7 -0.4 -0.5843 -0.9997 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K13 compound treatment 1.18227666E8 -4.37E8 -6.8 1.99154831E8 -3.33E8 -7.53 -10.1347 -0.9987 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K14 compound treatment 5.26190528E8 -2.86E7 -0.45 5.2782533E8 -4620000.0 -0.1 -0.3891 -0.8498 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K15 mock treatment 5.51346853E8 -3470000.0 -0.05 5.36407228E8 3960000.0 0.09 0.0251 0.2402 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K16 mock treatment 5.60362935E8 5550000.0 0.09 5.32680002E8 233000.0 0.01 0.0648 0.7488 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K17 compound treatment 2.15175146E8 -3.4E8 -5.29 2.58548945E8 -2.74E8 -6.19 -8.1178 -0.9969 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K18 compound treatment 5.27590797E8 -2.72E7 -0.42 5.24686573E8 -7760000.0 -0.18 -0.4238 -0.9237 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K19 compound treatment 2.33882971E8 -3.21E8 -5.0 2.88929052E8 -2.44E8 -5.5 -7.4263 -0.9988 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K20 compound treatment 5.34678569E8 -2.01E7 -0.31 5.31922253E8 -525000.0 -0.01 -0.2301 -0.7333 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K21 compound treatment 1.22075272E8 -4.33E8 -6.74 1.39725523E8 -3.93E8 -8.88 -11.0421 -0.9908 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K22 compound treatment 4.79966498E8 -7.48E7 -1.17 5.12592363E8 -1.99E7 -0.45 -1.1416 -0.9139 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K23 mock treatment 5.38875157E8 -1.59E7 -0.25 5.356694E8 3220000.0 0.07 -0.124 -0.4795 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 K24 mock treatment 5.11666263E8 -4.31E7 -0.67 5.0598764E8 -2.65E7 -0.6 -0.8981 -0.9983 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L01 compound treatment 4.79290394E8 -7.55E7 -1.18 5.10458785E8 -2.2E7 -0.5 -1.1832 -0.9265 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L02 compound treatment 5.42240757E8 -1.26E7 -0.2 5.63847967E8 3.14E7 0.71 0.3633 0.4935 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L03 compound treatment 5.18154765E8 -3.67E7 -0.57 5.18852903E8 -1.36E7 -0.31 -0.621 -0.9577 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L04 compound treatment 4.71954145E8 -8.29E7 -1.29 4.96447315E8 -3.6E7 -0.81 -1.4879 -0.9753 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L05 compound treatment 5.11995294E8 -4.28E7 -0.67 5.09169921E8 -2.33E7 -0.53 -0.8436 -0.9931 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L06 compound treatment 4.74962208E8 -7.99E7 -1.24 5.10587531E8 -2.19E7 -0.49 -1.2288 -0.9182 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L07 mock treatment 5.4601241E8 -8800000.0 -0.14 5.62443855E8 3.0E7 0.68 0.3824 0.5529 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L08 mock treatment 5.36754182E8 -1.81E7 -0.28 5.19301299E8 -1.31E7 -0.3 -0.409 -0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L09 compound treatment 4.92228881E8 -6.26E7 -0.97 5.20431736E8 -1.2E7 -0.27 -0.8813 -0.8709 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L10 compound treatment 4.07523405E8 -1.47E8 -2.29 4.61620429E8 -7.08E7 -1.6 -2.7541 -0.9845 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L11 compound treatment 4.59871757E8 -9.49E7 -1.48 5.01762199E8 -3.07E7 -0.69 -1.536 -0.9404 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L12 compound treatment 4.52687722E8 -1.02E8 -1.59 5.40543602E8 8100000.0 0.18 -0.9954 -0.6217 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L13 compound treatment 4.36064663E8 -1.19E8 -1.85 4.58579128E8 -7.39E7 -1.67 -2.4883 -0.9987 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L14 compound treatment 4.84702713E8 -7.01E7 -1.09 5.12187369E8 -2.03E7 -0.46 -1.096 -0.9255 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L15 mock treatment 5.52977826E8 -1840000.0 -0.03 5.62697765E8 3.03E7 0.68 0.4632 0.6769 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L16 mock treatment 5.35116901E8 -1.97E7 -0.31 5.62589441E8 3.01E7 0.68 0.2648 0.3544 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L17 compound treatment 5.2147933E8 -3.33E7 -0.52 5.44571738E8 1.21E7 0.27 -0.1734 -0.2953 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L18 compound treatment 4.71133019E8 -8.37E7 -1.3 5.13091658E8 -1.94E7 -0.44 -1.231 -0.8953 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L19 compound treatment 4.95344135E8 -5.95E7 -0.93 5.40193314E8 7750000.0 0.18 -0.5312 -0.5635 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L20 compound treatment 4.70273008E8 -8.45E7 -1.32 5.06662625E8 -2.58E7 -0.58 -1.3432 -0.9328 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L21 compound treatment 4.5883031E8 -9.6E7 -1.5 4.90151757E8 -4.23E7 -0.96 -1.7331 -0.9766 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L22 compound treatment 4.50876494E8 -1.04E8 -1.62 5.06657862E8 -2.58E7 -0.58 -1.5569 -0.9048 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L23 mock treatment 5.20313401E8 -3.45E7 -0.54 5.42371019E8 9920000.0 0.22 -0.2214 -0.3802 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 L24 mock treatment 5.20802314E8 -3.4E7 -0.53 5.33638446E8 1190000.0 0.03 -0.3556 -0.6703 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M01 compound treatment 6.700581E7 -4.88E8 -7.6 5.8431431E7 -4.74E8 -10.71 -12.9477 -0.9858 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M02 compound treatment 4.88741361E8 -6.61E7 -1.03 5.16582484E8 -1.59E7 -0.36 -0.9812 -0.9004 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M03 compound treatment 5.71912186E8 1.71E7 0.27 5.38522908E8 6080000.0 0.14 0.2854 0.9525 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M04 compound treatment 5.39653748E8 -1.52E7 -0.24 4.86313753E8 -4.61E7 -1.04 -0.9042 -0.8458 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M05 compound treatment 5.53890805E8 -923000.0 -0.01 5.08688092E8 -2.38E7 -0.54 -0.3898 -0.7258 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M06 compound treatment 5.21416418E8 -3.34E7 -0.52 4.61454847E8 -7.1E7 -1.6 -1.5023 -0.8907 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M07 compound treatment 5.65898556E8 1.11E7 0.17 5.33134306E8 688000.0 0.02 0.1331 0.7676 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M08 compound treatment 5.57083131E8 2270000.0 0.04 5.32256661E8 -190000.0 0.0 0.022 0.6166 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M09 mock treatment 5.63091089E8 8280000.0 0.13 5.18944171E8 -1.35E7 -0.31 -0.1246 -0.3762 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M10 mock treatment 5.71823642E8 1.7E7 0.26 5.22758023E8 -9690000.0 -0.22 0.0325 0.0946 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M11 compound treatment 5.40343225E8 -1.45E7 -0.23 4.87829522E8 -4.46E7 -1.01 -0.8724 -0.8443 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M12 compound treatment 5.34023984E8 -2.08E7 -0.32 4.89461023E8 -4.3E7 -0.97 -0.9159 -0.8944 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M13 mock treatment 5.39978212E8 -1.48E7 -0.23 5.16283025E8 -1.62E7 -0.37 -0.4217 -0.9756 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M14 mock treatment 5.50302312E8 -4510000.0 -0.07 5.30629462E8 -1820000.0 -0.04 -0.0787 -0.9673 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M15 compound treatment 5.47380177E8 -7430000.0 -0.12 4.50985043E8 -8.15E7 -1.84 -1.3837 -0.7501 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M16 compound treatment 5.56817553E8 2000000.0 0.03 5.09069034E8 -2.34E7 -0.53 -0.3515 -0.6642 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M17 compound treatment 4.9867489E8 -5.61E7 -0.87 4.82721858E8 -4.97E7 -1.12 -1.4129 -0.9923 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M18 compound treatment 5.5952015E8 4710000.0 0.07 4.9668486E8 -3.58E7 -0.81 -0.5197 -0.6403 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M19 mock treatment 5.28948249E8 -2.59E7 -0.4 5.1625891E8 -1.62E7 -0.37 -0.5436 -0.9988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M20 compound treatment 4.89257955E8 -6.56E7 -1.02 4.64084533E8 -6.84E7 -1.54 -1.8145 -0.9798 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M21 mock treatment 5.61134936E8 6320000.0 0.1 5.24891366E8 -7560000.0 -0.17 -0.0511 -0.2593 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M22 compound treatment 5.34609605E8 -2.02E7 -0.31 4.83999454E8 -4.84E7 -1.09 -0.9967 -0.8749 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M23 mock treatment 5.25322019E8 -2.95E7 -0.46 4.99526038E8 -3.29E7 -0.74 -0.8509 -0.9731 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 M24 compound treatment 5.03377507E8 -5.14E7 -0.8 4.69995792E8 -6.25E7 -1.41 -1.5645 -0.964 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N01 compound treatment 4.77034522E8 -7.78E7 -1.21 5.04102189E8 -2.83E7 -0.64 -1.3096 -0.9556 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N02 compound treatment 4.66800802E8 -8.8E7 -1.37 4.85508617E8 -4.69E7 -1.06 -1.7195 -0.992 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N03 compound treatment 5.14988832E8 -3.98E7 -0.62 4.63886927E8 -6.86E7 -1.55 -1.5343 -0.9193 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N04 compound treatment 5.13057192E8 -4.18E7 -0.65 5.07186034E8 -2.53E7 -0.57 -0.8636 -0.9979 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N05 compound treatment 4.90558532E8 -6.43E7 -1.0 4.59760705E8 -7.27E7 -1.64 -1.8693 -0.9718 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N06 compound treatment 3.33904539E8 -2.21E8 -3.44 3.18068573E8 -2.14E8 -4.84 -5.859 -0.9859 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N07 compound treatment 4.97365849E8 -5.74E7 -0.89 4.38307235E8 -9.41E7 -2.13 -2.1371 -0.9259 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N08 compound treatment 4.66075217E8 -8.87E7 -1.38 4.53289142E8 -7.92E7 -1.79 -2.2423 -0.9919 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N09 mock treatment 5.48109772E8 -6700000.0 -0.1 5.19364884E8 -1.31E7 -0.3 -0.2829 -0.9022 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N10 mock treatment 5.51145393E8 -3670000.0 -0.06 5.04423004E8 -2.8E7 -0.63 -0.4882 -0.7678 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N11 compound treatment 5.17853283E8 -3.7E7 -0.58 4.64831901E8 -6.76E7 -1.53 -1.4876 -0.911 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N12 compound treatment 4.73770756E8 -8.1E7 -1.26 4.77652855E8 -5.48E7 -1.24 -1.7682 -1.0 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N13 mock treatment 5.38895479E8 -1.59E7 -0.25 5.40726213E8 8280000.0 0.19 -0.043 -0.1385 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N14 mock treatment 5.53865031E8 -948000.0 -0.01 5.09823348E8 -2.26E7 -0.51 -0.372 -0.7272 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N15 compound treatment 5.457197E8 -9090000.0 -0.14 5.38297086E8 5850000.0 0.13 -0.0067 -0.0344 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N16 compound treatment 5.09229072E8 -4.56E7 -0.71 4.95394793E8 -3.71E7 -0.84 -1.0942 -0.9966 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N17 compound treatment 5.14078861E8 -4.07E7 -0.63 4.77812647E8 -5.46E7 -1.23 -1.3217 -0.9521 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N18 compound treatment 4.8968111E8 -6.51E7 -1.01 4.6000328E8 -7.24E7 -1.64 -1.8751 -0.9735 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N19 compound treatment 4.88287809E8 -6.65E7 -1.04 4.58063833E8 -7.44E7 -1.68 -1.9214 -0.973 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N20 compound treatment 4.6817392E8 -8.66E7 -1.35 4.67911019E8 -6.45E7 -1.46 -1.9856 -0.9992 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N21 compound treatment 4.82862419E8 -7.2E7 -1.12 4.80834543E8 -5.16E7 -1.17 -1.6173 -0.9998 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N22 compound treatment 4.8053618E8 -7.43E7 -1.16 4.47469603E8 -8.5E7 -1.92 -2.1761 -0.9706 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N23 compound treatment 4.90608497E8 -6.42E7 -1.0 4.41475962E8 -9.1E7 -2.06 -2.1609 -0.9452 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 N24 compound treatment 4.37142747E8 -1.18E8 -1.83 4.26805465E8 -1.06E8 -2.39 -2.9842 -0.9915 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O01 mock treatment 5.89104188E8 3.43E7 0.53 5.48086455E8 1.56E7 0.35 0.6276 0.9799 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O02 compound treatment 5.25825106E8 -2.9E7 -0.45 5.2370341E8 -8740000.0 -0.2 -0.459 -0.9313 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O03 mock treatment 5.60718098E8 5900000.0 0.09 5.44099853E8 1.17E7 0.26 0.2513 0.9007 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O04 mock treatment 6.09973221E8 5.52E7 0.86 5.39711824E8 7270000.0 0.16 0.7236 0.8273 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O05 mock treatment 5.66289084E8 1.15E7 0.18 5.48644607E8 1.62E7 0.37 0.3852 0.9457 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O06 mock treatment 5.74773176E8 2.0E7 0.31 5.45104723E8 1.27E7 0.29 0.4221 0.9991 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O07 mock treatment 5.76706821E8 2.19E7 0.34 5.43456417E8 1.1E7 0.25 0.4171 0.988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O08 mock treatment 5.85685477E8 3.09E7 0.48 5.43975506E8 1.15E7 0.26 0.5243 0.9586 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O09 mock treatment 5.88443217E8 3.36E7 0.52 5.41901125E8 9450000.0 0.21 0.5215 0.9218 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O10 mock treatment 5.74026271E8 1.92E7 0.3 5.32109927E8 -337000.0 -0.01 0.2062 0.6889 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O11 mock treatment 5.79328825E8 2.45E7 0.38 5.60605422E8 2.82E7 0.64 0.72 0.9701 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O12 mock treatment 5.48033127E8 -6780000.0 -0.11 5.58852557E8 2.64E7 0.6 0.3473 0.5731 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O13 mock treatment 5.71907481E8 1.71E7 0.27 5.13241548E8 -1.92E7 -0.43 -0.1186 -0.233 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O14 mock treatment 5.55780807E8 967000.0 0.02 5.41018013E8 8570000.0 0.19 0.1476 0.7598 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O15 mock treatment 5.60514636E8 5700000.0 0.09 5.2930573E8 -3140000.0 -0.07 0.0126 0.1108 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O16 mock treatment 5.44984252E8 -9830000.0 -0.15 5.57883577E8 2.54E7 0.57 0.2982 0.5013 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O17 mock treatment 5.37250188E8 -1.76E7 -0.27 5.43508067E8 1.11E7 0.25 -0.0167 -0.045 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O18 mock treatment 5.3141727E8 -2.34E7 -0.36 5.25848472E8 -6600000.0 -0.15 -0.3631 -0.9222 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O19 mock treatment 5.48376872E8 -6440000.0 -0.1 5.28525336E8 -3920000.0 -0.09 -0.1336 -0.9981 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O20 mock treatment 5.60285772E8 5470000.0 0.09 5.35491224E8 3040000.0 0.07 0.1089 0.9944 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O21 mock treatment 5.41916092E8 -1.29E7 -0.2 5.24577333E8 -7870000.0 -0.18 -0.2678 -0.9982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O22 mock treatment 5.48753691E8 -6060000.0 -0.09 5.44106021E8 1.17E7 0.26 0.1196 0.4272 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O23 mock treatment 5.54514975E8 -299000.0 0.0 4.92476404E8 -4.0E7 -0.9 -0.642 -0.7107 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 O24 mock treatment 5.36044961E8 -1.88E7 -0.29 5.29043958E8 -3400000.0 -0.08 -0.2611 -0.8637 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P01 compound treatment 5.56271739E8 1460000.0 0.02 5.5493024E8 2.25E7 0.51 0.3754 0.738 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P02 compound treatment 5.36698763E8 -1.81E7 -0.28 5.03145182E8 -2.93E7 -0.66 -0.6678 -0.9277 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P03 compound treatment 4.84532018E8 -7.03E7 -1.09 4.62571118E8 -6.99E7 -1.58 -1.8907 -0.984 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P04 compound treatment 5.32424656E8 -2.24E7 -0.35 5.15335476E8 -1.71E7 -0.39 -0.52 -0.9987 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P05 compound treatment 4.82641274E8 -7.22E7 -1.12 5.05849678E8 -2.66E7 -0.6 -1.2199 -0.957 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P06 compound treatment 5.23613494E8 -3.12E7 -0.49 5.65058872E8 3.26E7 0.74 0.1775 0.2011 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P07 compound treatment 4.68141832E8 -8.67E7 -1.35 5.05795157E8 -2.67E7 -0.6 -1.3805 -0.9339 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P08 compound treatment 5.42169347E8 -1.26E7 -0.2 5.33823377E8 1380000.0 0.03 -0.1173 -0.5881 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P09 compound treatment 4.54516741E8 -1.0E8 -1.56 4.80924881E8 -5.15E7 -1.16 -1.928 -0.9895 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P10 compound treatment 5.58759803E8 3950000.0 0.06 5.16550168E8 -1.59E7 -0.36 -0.2106 -0.5777 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P11 mock treatment 5.58182568E8 3370000.0 0.05 5.36842256E8 4400000.0 0.1 0.1073 0.9555 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P12 mock treatment 5.68857094E8 1.4E7 0.22 5.38010636E8 5560000.0 0.13 0.2436 0.9654 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P13 compound treatment 5.13635666E8 -4.12E7 -0.64 4.83119566E8 -4.93E7 -1.11 -1.2418 -0.9655 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P14 compound treatment 5.28216031E8 -2.66E7 -0.41 4.98078183E8 -3.44E7 -0.78 -0.8422 -0.9567 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P15 compound treatment 5.07468225E8 -4.73E7 -0.74 5.04884082E8 -2.76E7 -0.62 -0.9619 -0.9965 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P16 compound treatment 5.24177899E8 -3.06E7 -0.48 5.20289154E8 -1.22E7 -0.27 -0.5317 -0.9656 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P17 compound treatment 5.15134115E8 -3.97E7 -0.62 4.77890191E8 -5.46E7 -1.23 -1.3089 -0.949 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P18 compound treatment 5.42819808E8 -1.2E7 -0.19 4.99078461E8 -3.34E7 -0.75 -0.6653 -0.8564 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P19 compound treatment 5.27335745E8 -2.75E7 -0.43 4.98160422E8 -3.43E7 -0.77 -0.8506 -0.9608 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P20 compound treatment 5.30085629E8 -2.47E7 -0.39 5.09090093E8 -2.34E7 -0.53 -0.6456 -0.988 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P21 compound treatment 5.26347234E8 -2.85E7 -0.44 4.72813325E8 -5.96E7 -1.35 -1.2665 -0.8927 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P22 compound treatment 5.32736336E8 -2.21E7 -0.34 5.14985198E8 -1.75E7 -0.39 -0.5222 -0.9976 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P23 compound treatment 5.48489872E8 -6320000.0 -0.1 5.37702892E8 5260000.0 0.12 0.0143 0.093 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2130 P24 compound treatment 5.13817728E8 -4.1E7 -0.64 5.25777124E8 -6670000.0 -0.15 -0.5581 -0.8506 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A01 compound treatment 5.75928726E8 -134000.0 0.0 5.71184908E8 2.5E7 0.56 0.3974 0.7045 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A02 compound treatment 5.15467693E8 -6.06E7 -0.94 5.18705207E8 -2.75E7 -0.62 -1.1071 -0.9795 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A03 compound treatment 5.72407024E8 -3660000.0 -0.06 5.52375424E8 6150000.0 0.14 0.058 0.3864 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A04 compound treatment 6.02268248E8 2.62E7 0.41 5.65610458E8 1.94E7 0.44 0.5984 0.9994 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A05 compound treatment 5.9354927E8 1.75E7 0.27 5.84568028E8 3.83E7 0.87 0.8054 0.8866 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A06 compound treatment 5.86676336E8 1.06E7 0.17 5.54202532E8 7980000.0 0.18 0.2444 0.9991 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A07 compound treatment 5.85576837E8 9510000.0 0.15 5.75592249E8 2.94E7 0.66 0.5741 0.8442 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A08 compound treatment 5.74615072E8 -1450000.0 -0.02 5.36836441E8 -9390000.0 -0.21 -0.166 -0.7779 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A09 compound treatment 5.43560533E8 -3.25E7 -0.51 5.3692838E8 -9300000.0 -0.21 -0.5065 -0.9241 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A10 compound treatment 5.48850746E8 -2.72E7 -0.42 5.54312563E8 8090000.0 0.18 -0.1704 -0.3693 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A11 compound treatment 5.6797776E8 -8080000.0 -0.13 5.74230134E8 2.8E7 0.63 0.3585 0.5555 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A12 compound treatment 5.48554127E8 -2.75E7 -0.43 5.54515617E8 8290000.0 0.19 -0.1705 -0.3645 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A13 mock treatment 5.56411944E8 -1.97E7 -0.31 5.37022748E8 -9200000.0 -0.21 -0.3635 -0.9823 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A14 mock treatment 5.64555452E8 -1.15E7 -0.18 5.26465205E8 -1.98E7 -0.45 -0.4425 -0.9196 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A15 compound treatment 5.33542955E8 -4.25E7 -0.66 5.32497828E8 -1.37E7 -0.31 -0.6877 -0.9403 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A16 compound treatment 5.40102752E8 -3.6E7 -0.56 5.26812433E8 -1.94E7 -0.44 -0.7063 -0.9927 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A17 compound treatment 5.20672831E8 -5.54E7 -0.86 5.04339153E8 -4.19E7 -0.95 -1.2794 -0.9989 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A18 compound treatment 5.30653479E8 -4.54E7 -0.71 5.11348829E8 -3.49E7 -0.79 -1.0575 -0.9985 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A19 compound treatment 5.34611067E8 -4.15E7 -0.65 5.31197146E8 -1.5E7 -0.34 -0.6967 -0.955 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A20 compound treatment 5.17502756E8 -5.86E7 -0.91 5.23998163E8 -2.22E7 -0.5 -1.0002 -0.9605 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A21 compound treatment 5.32414998E8 -4.36E7 -0.68 5.14587791E8 -3.16E7 -0.71 -0.9863 -0.9997 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A22 compound treatment 3.89193555E8 -1.87E8 -2.91 4.20877969E8 -1.25E8 -2.83 -4.0613 -0.9999 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A23 compound treatment 5.44368457E8 -3.17E7 -0.49 5.10749106E8 -3.55E7 -0.8 -0.916 -0.9729 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 A24 compound treatment 5.30834749E8 -4.52E7 -0.7 5.18831674E8 -2.74E7 -0.62 -0.9359 -0.9979 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B01 compound treatment 5.87308688E8 1.12E7 0.18 5.50762308E8 4540000.0 0.1 0.1964 0.9675 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B02 compound treatment 5.5901929E8 -1.7E7 -0.27 5.4992536E8 3700000.0 0.08 -0.1286 -0.4619 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B03 compound treatment 5.60261332E8 -1.58E7 -0.25 5.54606327E8 8380000.0 0.19 -0.0401 -0.129 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B04 compound treatment 5.44031041E8 -3.2E7 -0.5 5.28561643E8 -1.77E7 -0.4 -0.635 -0.9939 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B05 compound treatment 5.7972173E8 3660000.0 0.06 5.61775956E8 1.56E7 0.35 0.2888 0.8112 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B06 compound treatment 5.43479112E8 -3.26E7 -0.51 5.20837672E8 -2.54E7 -0.57 -0.7646 -0.9981 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B07 compound treatment 5.49000225E8 -2.71E7 -0.42 5.13416621E8 -3.28E7 -0.74 -0.8223 -0.9642 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B08 compound treatment 5.61126377E8 -1.49E7 -0.23 5.53663896E8 7440000.0 0.17 -0.0456 -0.1589 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B09 compound treatment 5.48596889E8 -2.75E7 -0.43 5.32960647E8 -1.33E7 -0.3 -0.5145 -0.9849 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B10 compound treatment 5.9293784E8 1.69E7 0.26 5.39835067E8 -6390000.0 -0.14 0.0838 0.2793 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B11 compound treatment 4.61831523E8 -1.14E8 -1.78 5.07026332E8 -3.92E7 -0.89 -1.8845 -0.9481 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B12 compound treatment 5.01701288E8 -7.44E7 -1.16 4.94916615E8 -5.13E7 -1.16 -1.6389 -1.0 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B13 mock treatment 5.55453869E8 -2.06E7 -0.32 5.30605091E8 -1.56E7 -0.35 -0.4766 -0.9989 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B14 mock treatment 5.39335981E8 -3.67E7 -0.57 5.38968053E8 -7260000.0 -0.16 -0.5205 -0.8746 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B15 compound treatment 5.02376275E8 -7.37E7 -1.15 5.19908289E8 -2.63E7 -0.59 -1.2321 -0.9532 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B16 compound treatment 5.0820036E8 -6.79E7 -1.06 4.91705497E8 -5.45E7 -1.23 -1.6187 -0.9971 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B17 compound treatment 5.53936011E8 -2.21E7 -0.34 5.45647597E8 -576000.0 -0.01 -0.2529 -0.7333 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B18 compound treatment 5.44918097E8 -3.11E7 -0.49 5.22868035E8 -2.34E7 -0.53 -0.7163 -0.9991 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B19 compound treatment 5.5609848E8 -2.0E7 -0.31 5.4064133E8 -5580000.0 -0.13 -0.3091 -0.9211 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B20 compound treatment 5.58552432E8 -1.75E7 -0.27 5.49357951E8 3130000.0 0.07 -0.1428 -0.5067 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B21 compound treatment 5.00730424E8 -7.53E7 -1.17 5.10028567E8 -3.62E7 -0.82 -1.4081 -0.9844 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B22 compound treatment 5.51608831E8 -2.45E7 -0.38 5.26474533E8 -1.97E7 -0.45 -0.5849 -0.9969 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B23 compound treatment 5.48011663E8 -2.81E7 -0.44 5.29690003E8 -1.65E7 -0.37 -0.5732 -0.997 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 B24 compound treatment 5.30572989E8 -4.55E7 -0.71 5.25018593E8 -2.12E7 -0.48 -0.8399 -0.9819 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C01 compound treatment 6.06656245E8 3.06E7 0.48 5.62106782E8 1.59E7 0.36 0.5908 0.9902 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C02 compound treatment 6.01186376E8 2.51E7 0.39 5.53888353E8 7660000.0 0.17 0.3992 0.9328 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C03 compound treatment 5.62915341E8 -1.31E7 -0.2 5.27745455E8 -1.85E7 -0.42 -0.4401 -0.9462 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C04 compound treatment 5.92295023E8 1.62E7 0.25 5.87487364E8 4.13E7 0.93 0.8382 0.8675 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C05 compound treatment 5.42196906E8 -3.39E7 -0.53 5.13177984E8 -3.3E7 -0.75 -0.9011 -0.9855 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C06 compound treatment 6.03118682E8 2.71E7 0.42 5.85747476E8 3.95E7 0.89 0.9296 0.9412 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C07 compound treatment 5.86679719E8 1.06E7 0.17 5.7699105E8 3.08E7 0.7 0.6086 0.8515 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C08 compound treatment 5.87010608E8 1.09E7 0.17 5.73633416E8 2.74E7 0.62 0.5586 0.8694 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C09 compound treatment 5.82073216E8 6010000.0 0.09 5.84233084E8 3.8E7 0.86 0.6736 0.7796 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C10 compound treatment 5.98737319E8 2.27E7 0.35 5.43796222E8 -2430000.0 -0.05 0.2109 0.5902 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C11 mock treatment 6.03312083E8 2.72E7 0.42 5.96947594E8 5.07E7 1.15 1.1107 0.9086 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C12 mock treatment 6.01165322E8 2.51E7 0.39 5.9668858E8 5.05E7 1.14 1.0829 0.8982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C13 compound treatment 6.04920862E8 2.89E7 0.45 5.71096957E8 2.49E7 0.56 0.7153 0.9939 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C14 compound treatment 5.8415629E8 8090000.0 0.13 5.79404945E8 3.32E7 0.75 0.6194 0.8146 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C15 mock treatment 6.21211262E8 4.51E7 0.7 5.86910787E8 4.07E7 0.92 1.1475 0.9912 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C16 mock treatment 5.91773189E8 1.57E7 0.24 5.69108331E8 2.29E7 0.52 0.5387 0.9416 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C17 compound treatment 5.34144128E8 -4.19E7 -0.65 5.49772107E8 3550000.0 0.08 -0.405 -0.6156 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C18 compound treatment 5.79345597E8 3280000.0 0.05 5.70556462E8 2.43E7 0.55 0.425 0.7695 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C19 compound treatment 5.615739E8 -1.45E7 -0.23 5.34005606E8 -1.22E7 -0.28 -0.3548 -0.995 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C20 compound treatment 5.83155521E8 7090000.0 0.11 5.56709479E8 1.05E7 0.24 0.2457 0.9397 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C21 compound treatment 5.90851204E8 1.48E7 0.23 5.57327669E8 1.11E7 0.25 0.3403 0.9991 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C22 compound treatment 5.93177365E8 1.71E7 0.27 5.58187957E8 1.2E7 0.27 0.3797 1.0 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C23 compound treatment 5.64544438E8 -1.15E7 -0.18 5.23765826E8 -2.25E7 -0.51 -0.4858 -0.9023 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 C24 compound treatment 5.78385076E8 2320000.0 0.04 5.55997147E8 9770000.0 0.22 0.1818 0.8121 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D01 compound treatment 5.5986872E8 -1.62E7 -0.25 5.19531399E8 -2.67E7 -0.6 -0.6049 -0.9251 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D02 compound treatment 6.13018584E8 3.7E7 0.58 5.76510822E8 3.03E7 0.68 0.891 0.9963 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D03 compound treatment 5.20772983E8 -5.53E7 -0.86 5.39108516E8 -7120000.0 -0.16 -0.7227 -0.8249 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D04 compound treatment 5.55992299E8 -2.01E7 -0.31 5.51324601E8 5100000.0 0.12 -0.1395 -0.4188 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D05 compound treatment 5.59028537E8 -1.7E7 -0.27 5.74701729E8 2.85E7 0.64 0.2675 0.3842 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D06 compound treatment 5.99624652E8 2.36E7 0.37 5.67975405E8 2.18E7 0.49 0.6071 0.9896 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D07 compound treatment 6.06840188E8 3.08E7 0.48 5.59757408E8 1.35E7 0.31 0.5553 0.9764 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D08 compound treatment 6.26175257E8 5.01E7 0.78 5.50663805E8 4440000.0 0.1 0.6229 0.7915 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D09 compound treatment 5.75343882E8 -718000.0 -0.01 5.69703867E8 2.35E7 0.53 0.3673 0.692 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D10 compound treatment 5.85475673E8 9410000.0 0.15 5.65619011E8 1.94E7 0.44 0.4136 0.8949 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D11 mock treatment 5.8943631E8 1.34E7 0.21 5.61040312E8 1.48E7 0.33 0.3841 0.9739 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D12 mock treatment 5.76313321E8 251000.0 0.0 5.54763248E8 8540000.0 0.19 0.1392 0.7213 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D13 compound treatment 5.7793774E8 1880000.0 0.03 5.74049703E8 2.78E7 0.63 0.4653 0.7392 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D14 compound treatment 5.91956648E8 1.59E7 0.25 5.97225829E8 5.1E7 1.15 0.9901 0.8398 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D15 mock treatment 5.96872173E8 2.08E7 0.32 5.76233516E8 3.0E7 0.68 0.7088 0.9429 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D16 mock treatment 5.91776119E8 1.57E7 0.24 5.89404521E8 4.32E7 0.98 0.8631 0.8579 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D17 compound treatment 5.86752788E8 1.07E7 0.17 5.74134396E8 2.79E7 0.63 0.5638 0.8642 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D18 compound treatment 5.58688034E8 -1.74E7 -0.27 5.45996164E8 -228000.0 -0.01 -0.195 -0.7204 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D19 compound treatment 5.77308986E8 1250000.0 0.02 5.76757771E8 3.05E7 0.69 0.5017 0.7267 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D20 compound treatment 5.53260771E8 -2.28E7 -0.36 5.58043724E8 1.18E7 0.27 -0.0622 -0.1401 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D21 compound treatment 5.82700636E8 6640000.0 0.1 5.78979626E8 3.28E7 0.74 0.5966 0.7981 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D22 compound treatment 5.49306594E8 -2.68E7 -0.42 5.61600151E8 1.54E7 0.35 -0.049 -0.0902 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D23 compound treatment 5.88613757E8 1.26E7 0.2 5.56434904E8 1.02E7 0.23 0.3014 0.9966 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 D24 compound treatment 5.45875865E8 -3.02E7 -0.47 5.25752425E8 -2.05E7 -0.46 -0.6596 -1.0 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E01 mock treatment 5.46716505E8 -2.93E7 -0.46 5.29142822E8 -1.71E7 -0.39 -0.5962 -0.9965 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E02 mock treatment 5.21555539E8 -5.45E7 -0.85 5.08742464E8 -3.75E7 -0.85 -1.1993 -1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E03 compound treatment 5.19467104E8 -5.66E7 -0.88 5.24571817E8 -2.17E7 -0.49 -0.9693 -0.9614 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E04 compound treatment 5.17146537E8 -5.89E7 -0.92 4.99257346E8 -4.7E7 -1.06 -1.3994 -0.9974 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E05 compound treatment 5.29556199E8 -4.65E7 -0.72 5.27392779E8 -1.88E7 -0.43 -0.8131 -0.9679 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E06 compound treatment 5.45211185E8 -3.09E7 -0.48 5.11982185E8 -3.42E7 -0.77 -0.887 -0.9737 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E07 compound treatment 5.15783266E8 -6.03E7 -0.94 4.94300795E8 -5.19E7 -1.17 -1.4937 -0.9939 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E08 compound treatment 5.25933331E8 -5.01E7 -0.78 4.92245867E8 -5.4E7 -1.22 -1.4147 -0.9768 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E09 mock treatment 5.41131336E8 -3.49E7 -0.54 5.2105525E8 -2.52E7 -0.57 -0.7869 -0.9998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E10 mock treatment 5.39291006E8 -3.68E7 -0.57 5.21597939E8 -2.46E7 -0.56 -0.7985 -0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E11 compound treatment 5.05425773E8 -7.06E7 -1.1 5.01166595E8 -4.51E7 -1.02 -1.498 -0.9993 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E12 compound treatment 5.23056047E8 -5.3E7 -0.83 5.19213828E8 -2.7E7 -0.61 -1.0154 -0.989 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E13 compound treatment 4.91401859E8 -8.47E7 -1.32 4.65401173E8 -8.08E7 -1.83 -2.224 -0.9872 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E14 compound treatment 5.36375166E8 -3.97E7 -0.62 4.88939553E8 -5.73E7 -1.29 -1.3526 -0.9428 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E15 compound treatment 5.25050737E8 -5.1E7 -0.79 4.89270701E8 -5.7E7 -1.29 -1.472 -0.9731 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E16 compound treatment 5.37840702E8 -3.82E7 -0.6 5.13269509E8 -3.3E7 -0.74 -0.9476 -0.9938 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E17 mock treatment 5.53284511E8 -2.28E7 -0.35 5.18334464E8 -2.79E7 -0.63 -0.6966 -0.963 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E18 mock treatment 5.5323388E8 -2.28E7 -0.36 5.1399981E8 -3.22E7 -0.73 -0.7664 -0.9457 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E19 compound treatment 5.20605283E8 -5.55E7 -0.86 4.74859267E8 -7.14E7 -1.61 -1.7513 -0.9572 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E20 compound treatment 5.45639647E8 -3.04E7 -0.47 5.29294967E8 -1.69E7 -0.38 -0.6056 -0.9944 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E21 compound treatment 4.9943857E8 -7.66E7 -1.19 4.81419196E8 -6.48E7 -1.46 -1.8795 -0.9948 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E22 compound treatment 5.40241651E8 -3.58E7 -0.56 5.07179208E8 -3.9E7 -0.88 -1.0185 -0.9756 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E23 compound treatment 5.1475029E8 -6.13E7 -0.95 4.82866305E8 -6.34E7 -1.43 -1.6878 -0.9806 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 E24 compound treatment 5.3675271E8 -3.93E7 -0.61 5.03007636E8 -4.32E7 -0.98 -1.1236 -0.9747 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F01 mock treatment 5.91149384E8 1.51E7 0.23 5.41762814E8 -4460000.0 -0.1 0.0949 0.371 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F02 mock treatment 5.71391694E8 -4670000.0 -0.07 5.22226703E8 -2.4E7 -0.54 -0.4349 -0.7948 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F03 compound treatment 5.16124304E8 -5.99E7 -0.93 5.21405652E8 -2.48E7 -0.56 -1.0568 -0.9703 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F04 compound treatment 5.59775672E8 -1.63E7 -0.25 5.32690802E8 -1.35E7 -0.31 -0.3956 -0.9957 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F05 compound treatment 5.64796866E8 -1.13E7 -0.18 4.95595335E8 -5.06E7 -1.14 -0.9332 -0.8061 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F06 compound treatment 5.15054878E8 -6.1E7 -0.95 4.88586623E8 -5.76E7 -1.3 -1.593 -0.988 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F07 compound treatment 5.44651934E8 -3.14E7 -0.49 5.23000736E8 -2.32E7 -0.52 -0.7171 -0.9994 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F08 compound treatment 5.53846637E8 -2.22E7 -0.35 5.13168506E8 -3.31E7 -0.75 -0.7729 -0.9388 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F09 mock treatment 5.65066784E8 -1.1E7 -0.17 5.25930148E8 -2.03E7 -0.46 -0.4454 -0.9098 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F10 mock treatment 5.52101233E8 -2.4E7 -0.37 5.51484908E8 5260000.0 0.12 -0.1798 -0.4591 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F11 compound treatment 5.53413525E8 -2.26E7 -0.35 5.08407682E8 -3.78E7 -0.85 -0.8538 -0.9234 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F12 compound treatment 5.65478113E8 -1.06E7 -0.16 5.38712776E8 -7510000.0 -0.17 -0.2366 -0.9999 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F13 compound treatment 5.42292304E8 -3.38E7 -0.53 5.1750204E8 -2.87E7 -0.65 -0.8309 -0.9946 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F14 compound treatment 5.59143139E8 -1.69E7 -0.26 5.18847955E8 -2.74E7 -0.62 -0.6238 -0.9277 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F15 compound treatment 5.73624783E8 -2440000.0 -0.04 5.30705435E8 -1.55E7 -0.35 -0.2748 -0.7791 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F16 compound treatment 5.14518217E8 -6.15E7 -0.96 4.92608275E8 -5.36E7 -1.21 -1.5347 -0.9933 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F17 mock treatment 5.27836381E8 -4.82E7 -0.75 5.13051952E8 -3.32E7 -0.75 -1.0613 -1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F18 mock treatment 5.68964531E8 -7100000.0 -0.11 5.17552663E8 -2.87E7 -0.65 -0.5364 -0.816 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F19 compound treatment 5.55944093E8 -2.01E7 -0.31 5.24125393E8 -2.21E7 -0.5 -0.5747 -0.9748 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F20 compound treatment 5.17058744E8 -5.9E7 -0.92 4.96673339E8 -4.96E7 -1.12 -1.4417 -0.9952 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F21 compound treatment 5.44389371E8 -3.17E7 -0.49 5.19333E8 -2.69E7 -0.61 -0.7786 -0.9946 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F22 compound treatment 5.5948611E8 -1.66E7 -0.26 5.22958855E8 -2.33E7 -0.53 -0.5544 -0.9464 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F23 compound treatment 5.76114907E8 52600.0 0.0 5.6377902E8 1.76E7 0.4 0.2811 0.7086 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 F24 compound treatment 5.37271035E8 -3.88E7 -0.6 4.87853417E8 -5.84E7 -1.32 -1.36 -0.9373 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G01 compound treatment 5.80304449E8 4240000.0 0.07 5.40940944E8 -5280000.0 -0.12 -0.0377 -0.2763 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G02 compound treatment 5.59816707E8 -1.62E7 -0.25 5.48649999E8 2430000.0 0.05 -0.1402 -0.5413 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G03 mock treatment 5.83414822E8 7350000.0 0.11 5.60659417E8 1.44E7 0.33 0.3117 0.9014 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G04 mock treatment 5.87553089E8 1.15E7 0.18 5.49525982E8 3300000.0 0.07 0.1793 0.9248 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G05 compound treatment 5.68852106E8 -7210000.0 -0.11 5.29444456E8 -1.68E7 -0.38 -0.3476 -0.8788 PK04_181123 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G06 compound treatment 5.89942729E8 1.39E7 0.22 5.78699533E8 3.25E7 0.73 0.6719 0.8781 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G07 compound treatment 5.85347125E8 9280000.0 0.14 5.46949414E8 726000.0 0.02 0.1139 0.7823 PK04_181125 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G08 compound treatment 5.73336798E8 -2730000.0 -0.04 5.71103231E8 2.49E7 0.56 0.3676 0.6519 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G09 compound treatment 5.59400004E8 -1.67E7 -0.26 5.35993822E8 -1.02E7 -0.23 -0.347 -0.9983 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G10 compound treatment 6.0786202E8 3.18E7 0.5 5.63140809E8 1.69E7 0.38 0.6206 0.9918 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G11 compound treatment 5.65491802E8 -1.06E7 -0.16 5.18287507E8 -2.79E7 -0.63 -0.5629 -0.8627 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G12 compound treatment 6.0352959E8 2.75E7 0.43 5.85496841E8 3.93E7 0.89 0.9301 0.944 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G13 compound treatment 5.65891133E8 -1.02E7 -0.16 5.17985894E8 -2.82E7 -0.64 -0.5633 -0.8566 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G14 compound treatment 5.61791736E8 -1.43E7 -0.22 5.48859992E8 2640000.0 0.06 -0.115 -0.4999 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G15 compound treatment 5.7038395E8 -5680000.0 -0.09 5.35295328E8 -1.09E7 -0.25 -0.2372 -0.9041 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G16 compound treatment 6.03366271E8 2.73E7 0.43 5.61529248E8 1.53E7 0.35 0.5453 0.9947 3561954 PK04_181134 COc1ccccc1/C=C/CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G17 compound treatment 5.76404809E8 342000.0 0.01 5.30795079E8 -1.54E7 -0.35 -0.2428 -0.6962 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G18 compound treatment 5.80866978E8 4800000.0 0.07 5.71939302E8 2.57E7 0.58 0.4639 0.7916 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G19 mock treatment 5.98885764E8 2.28E7 0.36 5.26325466E8 -1.99E7 -0.45 -0.0666 -0.1162 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G20 mock treatment 5.8066544E8 4600000.0 0.07 5.51735944E8 5510000.0 0.12 0.1388 0.9656 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G21 compound treatment 5.54419256E8 -2.16E7 -0.34 4.9237723E8 -5.38E7 -1.22 -1.0989 -0.8702 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G22 compound treatment 5.8181068E8 5750000.0 0.09 5.56473543E8 1.02E7 0.23 0.2271 0.9145 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G23 compound treatment 5.27176643E8 -4.89E7 -0.76 5.14274789E8 -3.19E7 -0.72 -1.049 -0.9996 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 G24 compound treatment 5.72036357E8 -4030000.0 -0.06 5.30204037E8 -1.6E7 -0.36 -0.3003 -0.8174 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H01 compound treatment 5.902289E8 1.42E7 0.22 5.65694806E8 1.95E7 0.44 0.4672 0.949 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H02 compound treatment 6.03948881E8 2.79E7 0.43 5.4251995E8 -3700000.0 -0.08 0.2479 0.5605 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H03 mock treatment 6.21596665E8 4.55E7 0.71 5.94736546E8 4.85E7 1.1 1.2768 0.9778 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H04 mock treatment 6.1814205E8 4.21E7 0.66 5.98394454E8 5.22E7 1.18 1.2972 0.9616 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H05 compound treatment 5.72492077E8 -3570000.0 -0.06 5.75413461E8 2.92E7 0.66 0.4271 0.6452 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H06 compound treatment 5.83587361E8 7530000.0 0.12 5.51167019E8 4940000.0 0.11 0.1619 0.9997 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H07 compound treatment 6.33656137E8 5.76E7 0.9 5.87148075E8 4.09E7 0.92 1.2883 0.9999 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H08 compound treatment 5.90836445E8 1.48E7 0.23 5.51979919E8 5760000.0 0.13 0.2547 0.9635 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H09 compound treatment 5.98382864E8 2.23E7 0.35 5.57405788E8 1.12E7 0.25 0.4245 0.9877 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H10 compound treatment 5.65065556E8 -1.1E7 -0.17 4.99596599E8 -4.66E7 -1.05 -0.8663 -0.8114 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H11 compound treatment 6.10743946E8 3.47E7 0.54 5.79653104E8 3.34E7 0.76 0.9162 0.9865 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H12 compound treatment 5.76309683E8 247000.0 0.0 5.55490041E8 9270000.0 0.21 0.1508 0.72 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H13 compound treatment 5.89138422E8 1.31E7 0.2 5.3061594E8 -1.56E7 -0.35 -0.1054 -0.2588 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H14 compound treatment 5.99182312E8 2.31E7 0.36 5.5533536E8 9110000.0 0.21 0.4002 0.9648 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H15 compound treatment 6.10631779E8 3.46E7 0.54 5.76005574E8 2.98E7 0.67 0.8567 0.9939 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H16 compound treatment 5.87375742E8 1.13E7 0.18 5.64432803E8 1.82E7 0.41 0.4156 0.9284 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H17 compound treatment 5.94592617E8 1.85E7 0.29 5.68479118E8 2.23E7 0.5 0.5597 0.9652 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H18 compound treatment 5.99068401E8 2.3E7 0.36 5.68258744E8 2.2E7 0.5 0.6055 0.987 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H19 mock treatment 5.94417262E8 1.84E7 0.29 5.82716065E8 3.65E7 0.82 0.7853 0.8997 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H20 mock treatment 5.90836443E8 1.48E7 0.23 5.57585888E8 1.14E7 0.26 0.3443 0.9985 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H21 compound treatment 6.06783394E8 3.07E7 0.48 5.73623812E8 2.74E7 0.62 0.7762 0.9919 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H22 compound treatment 5.94497078E8 1.84E7 0.29 5.62073687E8 1.58E7 0.36 0.4563 0.994 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H23 compound treatment 5.84493448E8 8430000.0 0.13 5.49629003E8 3410000.0 0.08 0.1473 0.9676 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 H24 compound treatment 5.60853672E8 -1.52E7 -0.24 5.37046796E8 -9180000.0 -0.21 -0.3142 -0.9978 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I01 compound treatment 5.25751811E8 -5.03E7 -0.78 4.79449024E8 -6.68E7 -1.51 -1.6212 -0.9534 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I02 compound treatment 5.40766557E8 -3.53E7 -0.55 5.26124208E8 -2.01E7 -0.45 -0.71 -0.9955 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I03 compound treatment 5.25092509E8 -5.1E7 -0.79 4.7883382E8 -6.74E7 -1.52 -1.6383 -0.9539 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I04 compound treatment 5.48666719E8 -2.74E7 -0.43 5.16323702E8 -2.99E7 -0.68 -0.7796 -0.9754 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I05 mock treatment 5.72952138E8 -3110000.0 -0.05 5.13076229E8 -3.31E7 -0.75 -0.564 -0.7513 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I06 mock treatment 5.73427955E8 -2630000.0 -0.04 5.1741799E8 -2.88E7 -0.65 -0.4894 -0.7502 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I07 compound treatment 5.68179589E8 -7880000.0 -0.12 5.04253156E8 -4.2E7 -0.95 -0.7575 -0.792 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I08 compound treatment 5.54606252E8 -2.15E7 -0.33 5.27396874E8 -1.88E7 -0.43 -0.5372 -0.9929 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I09 compound treatment 5.61052145E8 -1.5E7 -0.23 5.0948503E8 -3.67E7 -0.83 -0.7524 -0.8723 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I10 compound treatment 5.33297741E8 -4.28E7 -0.67 5.18226106E8 -2.8E7 -0.63 -0.9184 -0.9997 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I11 compound treatment 5.60342324E8 -1.57E7 -0.24 4.96040701E8 -5.02E7 -1.13 -0.9751 -0.8404 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I12 compound treatment 5.58526567E8 -1.75E7 -0.27 5.36338949E8 -9880000.0 -0.22 -0.3511 -0.995 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I13 compound treatment 5.54962793E8 -2.11E7 -0.33 5.13530904E8 -3.27E7 -0.74 -0.7548 -0.9335 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I14 compound treatment 5.71351358E8 -4710000.0 -0.07 5.25433509E8 -2.08E7 -0.47 -0.3841 -0.8077 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I15 compound treatment 5.60620462E8 -1.54E7 -0.24 4.93476152E8 -5.27E7 -1.19 -1.013 -0.833 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I16 compound treatment 5.65512075E8 -1.06E7 -0.16 5.13959138E8 -3.23E7 -0.73 -0.6318 -0.8453 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I17 compound treatment 5.19708054E8 -5.64E7 -0.88 5.0037934E8 -4.58E7 -1.04 -1.3533 -0.9966 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I18 compound treatment 5.71087571E8 -4970000.0 -0.08 5.01878945E8 -4.43E7 -1.0 -0.7635 -0.7595 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I19 compound treatment 5.12506759E8 -6.36E7 -0.99 5.16649242E8 -2.96E7 -0.67 -1.1726 -0.9817 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I20 compound treatment 5.58969371E8 -1.71E7 -0.27 5.23415506E8 -2.28E7 -0.52 -0.5528 -0.9527 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I21 mock treatment 5.42202804E8 -3.39E7 -0.53 5.18179879E8 -2.8E7 -0.63 -0.8211 -0.9958 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I22 mock treatment 5.37451518E8 -3.86E7 -0.6 5.21812848E8 -2.44E7 -0.55 -0.8154 -0.9991 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I23 compound treatment 5.23126E8 -5.29E7 -0.82 4.76584528E8 -6.96E7 -1.57 -1.6959 -0.9545 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 I24 compound treatment 5.3529072E8 -4.08E7 -0.64 4.89886021E8 -5.63E7 -1.27 -1.3494 -0.9484 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J01 compound treatment 5.31624382E8 -4.44E7 -0.69 5.05970064E8 -4.03E7 -0.91 -1.1327 -0.9909 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J02 compound treatment 5.23175747E8 -5.29E7 -0.82 4.5263899E8 -9.36E7 -2.12 -2.078 -0.9155 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J03 compound treatment 5.51832567E8 -2.42E7 -0.38 4.96897797E8 -4.93E7 -1.11 -1.0551 -0.8965 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J04 compound treatment 5.38544424E8 -3.75E7 -0.58 4.61049206E8 -8.52E7 -1.92 -1.7744 -0.882 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J05 mock treatment 5.57558699E8 -1.85E7 -0.29 5.03428855E8 -4.28E7 -0.97 -0.8877 -0.8796 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J06 mock treatment 5.5455357E8 -2.15E7 -0.34 5.17668653E8 -2.86E7 -0.65 -0.6932 -0.9534 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J07 compound treatment 5.93751057E8 1.77E7 0.28 5.17261935E8 -2.9E7 -0.65 -0.268 -0.3774 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J08 compound treatment 5.43799256E8 -3.23E7 -0.5 4.91412556E8 -5.48E7 -1.24 -1.2313 -0.9211 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J09 compound treatment 5.01334832E8 -7.47E7 -1.16 5.09052473E8 -3.72E7 -0.84 -1.4171 -0.9872 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J10 compound treatment 4.93804956E8 -8.23E7 -1.28 4.69008705E8 -7.72E7 -1.75 -2.1399 -0.9885 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J11 compound treatment 5.82558564E8 6500000.0 0.1 5.00309179E8 -4.59E7 -1.04 -0.6622 -0.6351 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J12 compound treatment 5.28363567E8 -4.77E7 -0.74 4.95901232E8 -5.03E7 -1.14 -1.3295 -0.9787 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J13 compound treatment 5.7818252E8 2120000.0 0.03 4.70073183E8 -7.62E7 -1.72 -1.1936 -0.6934 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J14 compound treatment 5.69345854E8 -6720000.0 -0.1 4.86783751E8 -5.94E7 -1.34 -1.0239 -0.7599 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J15 compound treatment 6.79072872E8 1.03E8 1.6 6.47390224E8 1.01E8 2.29 2.7513 0.985 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J16 compound treatment 5.56152886E8 -1.99E7 -0.31 4.95939958E8 -5.03E7 -1.14 -1.0229 -0.8683 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J17 compound treatment 5.58406237E8 -1.77E7 -0.28 5.28553638E8 -1.77E7 -0.4 -0.4768 -0.9834 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J18 compound treatment 5.61805481E8 -1.43E7 -0.22 5.27698046E8 -1.85E7 -0.42 -0.4531 -0.956 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J19 compound treatment 5.51389228E8 -2.47E7 -0.38 5.10450322E8 -3.58E7 -0.81 -0.8434 -0.9422 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J20 compound treatment 5.77713712E8 1650000.0 0.03 5.13016473E8 -3.32E7 -0.75 -0.5125 -0.6825 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J21 mock treatment 5.63592764E8 -1.25E7 -0.19 5.33860808E8 -1.24E7 -0.28 -0.3349 -0.9842 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J22 mock treatment 5.25150397E8 -5.09E7 -0.79 5.1723453E8 -2.9E7 -0.66 -1.024 -0.9955 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J23 compound treatment 5.58201731E8 -1.79E7 -0.28 5.11939434E8 -3.43E7 -0.77 -0.7446 -0.9045 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 J24 compound treatment 5.30432096E8 -4.56E7 -0.71 5.00270948E8 -4.6E7 -1.04 -1.2369 -0.9829 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K01 compound treatment 5.70936293E8 -5130000.0 -0.08 5.62282946E8 1.61E7 0.36 0.2002 0.5387 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K02 compound treatment 5.7819203E8 2130000.0 0.03 5.22746757E8 -2.35E7 -0.53 -0.3517 -0.6616 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K03 compound treatment 5.39405013E8 -3.67E7 -0.57 5.11820693E8 -3.44E7 -0.78 -0.9535 -0.9885 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K04 compound treatment 5.69065583E8 -7000000.0 -0.11 5.40297018E8 -5930000.0 -0.13 -0.1718 -0.9948 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K05 compound treatment 5.82156161E8 6090000.0 0.09 5.14473341E8 -3.18E7 -0.72 -0.4403 -0.6083 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K06 compound treatment 5.89143323E8 1.31E7 0.2 5.55148226E8 8920000.0 0.2 0.2867 1.0 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K07 mock treatment 6.15216236E8 3.92E7 0.61 5.37994156E8 -8230000.0 -0.19 0.2997 0.4701 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K08 mock treatment 5.96361412E8 2.03E7 0.32 5.30421259E8 -1.58E7 -0.36 -0.029 -0.0607 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K09 compound treatment 5.49393076E8 -2.67E7 -0.42 5.53132963E8 6910000.0 0.16 -0.1833 -0.4131 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K10 compound treatment 6.08394163E8 3.23E7 0.5 5.40684033E8 -5540000.0 -0.13 0.2676 0.5156 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K11 compound treatment 5.22601945E8 -5.35E7 -0.83 5.13007321E8 -3.32E7 -0.75 -1.1196 -0.9987 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K12 compound treatment 5.49589899E8 -2.65E7 -0.41 5.26286938E8 -1.99E7 -0.45 -0.6102 -0.999 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K13 compound treatment 5.56003773E8 -2.01E7 -0.31 5.04604255E8 -4.16E7 -0.94 -0.886 -0.894 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K14 compound treatment 5.57020698E8 -1.9E7 -0.3 5.43014303E8 -3210000.0 -0.07 -0.261 -0.8548 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K15 mock treatment 5.97343481E8 2.13E7 0.33 5.40321576E8 -5900000.0 -0.13 0.1401 0.392 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K16 mock treatment 5.74662855E8 -1400000.0 -0.02 5.63529243E8 1.73E7 0.39 0.2611 0.6667 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K17 compound treatment 5.5334439E8 -2.27E7 -0.35 5.31533528E8 -1.47E7 -0.33 -0.485 -0.9995 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K18 compound treatment 5.74903637E8 -1160000.0 -0.02 5.30632217E8 -1.56E7 -0.35 -0.2619 -0.7424 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K19 compound treatment 5.38574238E8 -3.75E7 -0.58 5.39959537E8 -6260000.0 -0.14 -0.513 -0.8538 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K20 compound treatment 5.6671057E8 -9350000.0 -0.15 5.67105983E8 2.09E7 0.47 0.2307 0.4671 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K21 compound treatment 5.56169142E8 -1.99E7 -0.31 5.34137915E8 -1.21E7 -0.27 -0.4122 -0.998 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K22 compound treatment 5.61233294E8 -1.48E7 -0.23 5.44816037E8 -1410000.0 -0.03 -0.1858 -0.797 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K23 mock treatment 5.90573889E8 1.45E7 0.23 5.45318056E8 -906000.0 -0.02 0.1454 0.6404 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 K24 mock treatment 5.41373937E8 -3.47E7 -0.54 5.23694353E8 -2.25E7 -0.51 -0.7421 -0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L01 compound treatment 7.97249106E8 2.21E8 3.45 7.17840334E8 1.72E8 3.88 5.1787 0.9983 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L02 compound treatment 5.64627837E8 -1.14E7 -0.18 5.25320097E8 -2.09E7 -0.47 -0.46 -0.9111 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L03 compound treatment 5.62466815E8 -1.36E7 -0.21 5.52863632E8 6640000.0 0.15 -0.0436 -0.1681 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L04 compound treatment 6.2031006E8 4.42E7 0.69 5.97244981E8 5.1E7 1.15 1.3027 0.9697 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L05 compound treatment 5.90374053E8 1.43E7 0.22 5.64608522E8 1.84E7 0.42 0.4514 0.9574 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L06 compound treatment 5.80542143E8 4480000.0 0.07 5.85479371E8 3.93E7 0.89 0.6767 0.7604 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L07 mock treatment 5.83121645E8 7060000.0 0.11 5.53158439E8 6930000.0 0.16 0.1886 0.985 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L08 mock treatment 6.03651747E8 2.76E7 0.43 5.72810538E8 2.66E7 0.6 0.7287 0.9865 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L09 compound treatment 5.92031235E8 1.6E7 0.25 5.40219937E8 -6000000.0 -0.14 0.0799 0.2821 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L10 compound treatment 5.89349063E8 1.33E7 0.21 5.61990712E8 1.58E7 0.36 0.3983 0.9666 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L11 compound treatment 6.04850863E8 2.88E7 0.45 5.63097233E8 1.69E7 0.38 0.5867 0.9967 1006359 PK04_181227 Cc1cccc[n+]1C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L12 compound treatment 5.81748312E8 5690000.0 0.09 5.45721193E8 -503000.0 -0.01 0.0546 0.6114 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L13 compound treatment 5.58595758E8 -1.75E7 -0.27 5.53529708E8 7310000.0 0.17 -0.0756 -0.2376 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L14 compound treatment 5.6843282E8 -7630000.0 -0.12 5.84721797E8 3.85E7 0.87 0.5312 0.6049 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L15 mock treatment 5.83162411E8 7100000.0 0.11 5.6343027E8 1.72E7 0.39 0.3532 0.8736 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L16 mock treatment 6.15713419E8 3.97E7 0.62 5.40566152E8 -5660000.0 -0.13 0.3463 0.5491 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L17 compound treatment 5.86637132E8 1.06E7 0.16 5.71065077E8 2.48E7 0.56 0.5134 0.8776 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L18 compound treatment 5.92410228E8 1.63E7 0.25 5.72660534E8 2.64E7 0.6 0.6025 0.9277 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L19 compound treatment 5.83010593E8 6950000.0 0.11 5.23402481E8 -2.28E7 -0.52 -0.2882 -0.5468 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L20 compound treatment 5.81491737E8 5430000.0 0.08 5.60725233E8 1.45E7 0.33 0.2915 0.8614 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L21 compound treatment 5.6202268E8 -1.4E7 -0.22 5.40377227E8 -5850000.0 -0.13 -0.2481 -0.9709 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L22 compound treatment 5.90159959E8 1.41E7 0.22 5.89661237E8 4.34E7 0.98 0.8494 0.8444 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L23 mock treatment 5.96670853E8 2.06E7 0.32 5.56217576E8 9990000.0 0.23 0.3867 0.9852 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 L24 mock treatment 5.61402975E8 -1.47E7 -0.23 5.40426079E8 -5800000.0 -0.13 -0.2541 -0.9652 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M01 compound treatment 4.7184211E8 -1.04E8 -1.62 4.62238261E8 -8.4E7 -1.9 -2.49 -0.997 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M02 compound treatment 5.2553926E8 -5.05E7 -0.79 5.21928051E8 -2.43E7 -0.55 -0.9447 -0.9845 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M03 compound treatment 5.4326782E8 -3.28E7 -0.51 5.26407586E8 -1.98E7 -0.45 -0.6779 -0.9979 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M04 compound treatment 5.0646067E8 -6.96E7 -1.08 4.86176671E8 -6.0E7 -1.36 -1.7262 -0.9938 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M05 compound treatment 5.50626047E8 -2.54E7 -0.4 5.15314634E8 -3.09E7 -0.7 -0.7741 -0.9639 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M06 compound treatment 6.04335589E8 2.83E7 0.44 5.34568489E8 -1.17E7 -0.26 0.1251 0.2439 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M07 compound treatment 5.6176251E8 -1.43E7 -0.22 5.57275135E8 1.11E7 0.25 0.0191 0.0571 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M08 compound treatment 5.70807859E8 -5250000.0 -0.08 5.26434389E8 -1.98E7 -0.45 -0.3741 -0.8228 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M09 mock treatment 5.83507823E8 7450000.0 0.12 5.39212369E8 -7010000.0 -0.16 -0.03 -0.153 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M10 mock treatment 5.90455979E8 1.44E7 0.22 5.41544298E8 -4680000.0 -0.11 0.0837 0.3378 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M11 compound treatment 5.55766348E8 -2.03E7 -0.32 5.18290946E8 -2.79E7 -0.63 -0.6699 -0.9489 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M12 compound treatment 5.79295165E8 3230000.0 0.05 5.38034811E8 -8190000.0 -0.19 -0.0953 -0.4967 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M13 mock treatment 5.81565361E8 5500000.0 0.09 5.77339251E8 3.11E7 0.7 0.5579 0.7875 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M14 mock treatment 5.81919201E8 5860000.0 0.09 5.43400699E8 -2820000.0 -0.06 0.0194 0.1742 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M15 compound treatment 5.49810406E8 -2.63E7 -0.41 5.20068088E8 -2.62E7 -0.59 -0.7071 -0.9838 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M16 compound treatment 5.2058081E8 -5.55E7 -0.86 5.21832517E8 -2.44E7 -0.55 -1.0009 -0.9764 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M17 compound treatment 5.4037415E8 -3.57E7 -0.56 5.15235905E8 -3.1E7 -0.7 -0.8883 -0.9935 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M18 compound treatment 5.39622174E8 -3.64E7 -0.57 5.62256114E8 1.6E7 0.36 -0.1451 -0.2155 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M19 compound treatment 5.42480284E8 -3.36E7 -0.52 5.17122235E8 -2.91E7 -0.66 -0.8349 -0.9936 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M20 compound treatment 5.34577953E8 -4.15E7 -0.65 5.21587211E8 -2.46E7 -0.56 -0.8506 -0.9973 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M21 compound treatment 5.20392381E8 -5.57E7 -0.87 5.25695193E8 -2.05E7 -0.46 -0.9412 -0.9571 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M22 compound treatment 5.61518082E8 -1.45E7 -0.23 5.39947189E8 -6280000.0 -0.14 -0.2605 -0.9746 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M23 compound treatment 5.44010263E8 -3.21E7 -0.5 5.05819896E8 -4.04E7 -0.91 -0.9987 -0.9596 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 M24 compound treatment 5.37345171E8 -3.87E7 -0.6 5.16406529E8 -2.98E7 -0.67 -0.9029 -0.9985 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N01 compound treatment 5.63621089E8 -1.24E7 -0.19 5.61833618E8 1.56E7 0.35 0.1124 0.2793 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N02 compound treatment 6.1371425E8 3.77E7 0.59 5.48446632E8 2220000.0 0.05 0.4502 0.7649 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N03 compound treatment 5.602483E8 -1.58E7 -0.25 5.39068812E8 -7160000.0 -0.16 -0.2885 -0.9792 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N04 compound treatment 5.78775719E8 2710000.0 0.04 5.51969484E8 5750000.0 0.13 0.1217 0.8912 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N05 compound treatment 5.82897245E8 6830000.0 0.11 5.44386928E8 -1840000.0 -0.04 0.0459 0.4019 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N06 compound treatment 5.52757501E8 -2.33E7 -0.36 5.49213512E8 2990000.0 0.07 -0.2089 -0.5658 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N07 compound treatment 5.50175498E8 -2.59E7 -0.4 5.44382862E8 -1840000.0 -0.04 -0.3145 -0.776 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N08 compound treatment 5.86198574E8 1.01E7 0.16 5.58936348E8 1.27E7 0.29 0.3148 0.9602 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N09 mock treatment 5.87829108E8 1.18E7 0.18 5.58703635E8 1.25E7 0.28 0.329 0.9782 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N10 mock treatment 5.81326708E8 5260000.0 0.08 5.30424926E8 -1.58E7 -0.36 -0.1945 -0.5309 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N11 compound treatment 5.6755533E8 -8510000.0 -0.13 5.27810149E8 -1.84E7 -0.42 -0.388 -0.8883 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N12 compound treatment 5.85347785E8 9290000.0 0.14 5.64165353E8 1.79E7 0.41 0.389 0.9036 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N13 mock treatment 5.8603776E8 9980000.0 0.16 5.79883252E8 3.37E7 0.76 0.6478 0.8343 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N14 mock treatment 5.72951247E8 -3110000.0 -0.05 5.50960602E8 4740000.0 0.11 0.0414 0.3526 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N15 compound treatment 5.77346354E8 1280000.0 0.02 5.73808988E8 2.76E7 0.62 0.455 0.7294 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N16 compound treatment 5.84880478E8 8820000.0 0.14 5.70827637E8 2.46E7 0.56 0.4903 0.856 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N17 compound treatment 5.60006806E8 -1.61E7 -0.25 5.47216208E8 992000.0 0.02 -0.161 -0.6411 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N18 compound treatment 5.59188488E8 -1.69E7 -0.26 5.75663258E8 2.94E7 0.67 0.2846 0.3979 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N19 compound treatment 5.61248364E8 -1.48E7 -0.23 5.28295618E8 -1.79E7 -0.41 -0.4497 -0.9644 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N20 compound treatment 5.65101294E8 -1.1E7 -0.17 5.45236726E8 -987000.0 -0.02 -0.1365 -0.7928 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N21 compound treatment 5.530162E8 -2.3E7 -0.36 5.24783997E8 -2.14E7 -0.48 -0.5965 -0.9891 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N22 compound treatment 5.64047115E8 -1.2E7 -0.19 5.45729817E8 -494000.0 -0.01 -0.1402 -0.748 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N23 compound treatment 5.38819304E8 -3.72E7 -0.58 5.11326274E8 -3.49E7 -0.79 -0.9679 -0.9886 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 N24 compound treatment 5.32168284E8 -4.39E7 -0.68 5.22840992E8 -2.34E7 -0.53 -0.8571 -0.9919 1004341 PK04_181276 c1ccc2cnccc2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O01 compound treatment 5.88114541E8 1.21E7 0.19 5.62145568E8 1.59E7 0.36 0.3872 0.954 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O02 compound treatment 5.46592801E8 -2.95E7 -0.46 5.60909146E8 1.47E7 0.33 -0.0899 -0.1587 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O03 compound treatment 5.60776014E8 -1.53E7 -0.24 5.66266628E8 2.0E7 0.45 0.1519 0.2969 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O04 compound treatment 5.72798564E8 -3260000.0 -0.05 5.44653234E8 -1570000.0 -0.04 -0.061 -0.9846 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O05 compound treatment 5.82188713E8 6130000.0 0.1 5.64840552E8 1.86E7 0.42 0.365 0.846 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O06 compound treatment 5.51882076E8 -2.42E7 -0.38 5.62559216E8 1.63E7 0.37 -0.0053 -0.01 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O07 compound treatment 5.54294582E8 -2.18E7 -0.34 5.34206725E8 -1.2E7 -0.27 -0.4318 -0.994 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O08 compound treatment 5.94626229E8 1.86E7 0.29 5.53915249E8 7690000.0 0.17 0.3274 0.9703 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O09 compound treatment 5.47946525E8 -2.81E7 -0.44 5.09104797E8 -3.71E7 -0.84 -0.9029 -0.9541 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O10 compound treatment 5.6643089E8 -9630000.0 -0.15 5.4284724E8 -3380000.0 -0.08 -0.16 -0.9509 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O11 mock treatment 5.85529007E8 9470000.0 0.15 5.60792678E8 1.46E7 0.33 0.3371 0.9344 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O12 mock treatment 5.82619591E8 6560000.0 0.1 5.54638629E8 8410000.0 0.19 0.2067 0.9575 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O13 compound treatment 5.73823292E8 -2240000.0 -0.03 5.43598367E8 -2630000.0 -0.06 -0.0666 -0.9679 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O14 compound treatment 5.77893788E8 1830000.0 0.03 5.55037262E8 8810000.0 0.2 0.161 0.8002 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O15 compound treatment 5.53140672E8 -2.29E7 -0.36 5.29166855E8 -1.71E7 -0.39 -0.525 -0.9993 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O16 compound treatment 5.74041786E8 -2020000.0 -0.03 5.39195077E8 -7030000.0 -0.16 -0.1346 -0.831 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O17 compound treatment 5.49894608E8 -2.62E7 -0.41 5.42823565E8 -3400000.0 -0.08 -0.3425 -0.8259 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O18 compound treatment 5.62143624E8 -1.39E7 -0.22 5.36486863E8 -9740000.0 -0.22 -0.3089 -1.0 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O19 compound treatment 5.56716496E8 -1.93E7 -0.3 5.20799472E8 -2.54E7 -0.57 -0.6194 -0.9546 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O20 compound treatment 5.75228252E8 -834000.0 -0.01 5.40871682E8 -5350000.0 -0.12 -0.0947 -0.7786 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O21 compound treatment 5.76353867E8 292000.0 0.0 5.58707654E8 1.25E7 0.28 0.2027 0.7184 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O22 compound treatment 5.56580986E8 -1.95E7 -0.3 5.4250818E8 -3720000.0 -0.08 -0.2739 -0.8701 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O23 compound treatment 5.55341467E8 -2.07E7 -0.32 5.30884187E8 -1.53E7 -0.35 -0.4734 -0.9994 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 O24 compound treatment 5.41031973E8 -3.5E7 -0.55 5.48634338E8 2410000.0 0.05 -0.3473 -0.6334 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P01 compound treatment 5.81193106E8 5130000.0 0.08 5.41655998E8 -4570000.0 -0.1 -0.0165 -0.1263 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P02 compound treatment 5.78581309E8 2520000.0 0.04 5.50521925E8 4300000.0 0.1 0.0964 0.9205 1015751 PK04_181300 Cc1ccncc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P03 compound treatment 5.80888159E8 4830000.0 0.08 5.37610539E8 -8610000.0 -0.19 -0.0845 -0.4049 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P04 compound treatment 6.67162724E8 9.11E7 1.42 6.04622112E8 5.84E7 1.32 1.9366 0.9993 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P05 compound treatment 5.91421097E8 1.54E7 0.24 5.39335096E8 -6890000.0 -0.16 0.0591 0.207 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P06 compound treatment 6.44573473E8 6.85E7 1.07 5.75138819E8 2.89E7 0.65 1.2167 0.9723 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P07 compound treatment 5.85325237E8 9260000.0 0.14 5.4133296E8 -4890000.0 -0.11 0.0239 0.1313 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P08 compound treatment 8.78314869E8 3.02E8 4.71 7.99464555E8 2.53E8 5.72 7.3759 0.9953 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P09 compound treatment 5.506044E8 -2.55E7 -0.4 5.60309195E8 1.41E7 0.32 -0.0553 -0.1087 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P10 compound treatment 5.76812773E8 750000.0 0.01 5.56384475E8 1.02E7 0.23 0.1706 0.7421 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P11 mock treatment 5.78638639E8 2580000.0 0.04 5.68553328E8 2.23E7 0.5 0.3852 0.7609 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P12 mock treatment 5.74613264E8 -1450000.0 -0.02 5.7158963E8 2.54E7 0.57 0.3894 0.6787 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P13 compound treatment 5.7947908E8 3420000.0 0.05 5.40505592E8 -5720000.0 -0.13 -0.0538 -0.3846 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P14 compound treatment 5.90941331E8 1.49E7 0.23 5.58706001E8 1.25E7 0.28 0.3633 0.9952 1009497 PK04_181310 Cc1cc[n+](C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P15 compound treatment 5.88541281E8 1.25E7 0.19 5.62391203E8 1.62E7 0.37 0.3958 0.9564 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P16 compound treatment 6.46900491E8 7.08E7 1.1 6.16246231E8 7.0E7 1.58 1.8992 0.9845 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P17 compound treatment 5.90636914E8 1.46E7 0.23 5.44741208E8 -1480000.0 -0.03 0.1368 0.5963 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P18 compound treatment 5.74701118E8 -1360000.0 -0.02 5.54389118E8 8170000.0 0.18 0.1155 0.6218 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P19 compound treatment 5.88442861E8 1.24E7 0.19 5.54987897E8 8760000.0 0.2 0.2764 0.9999 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P20 compound treatment 6.39737475E8 6.37E7 0.99 6.23980195E8 7.78E7 1.76 1.9439 0.9634 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P21 compound treatment 5.65143795E8 -1.09E7 -0.17 5.53633526E8 7410000.0 0.17 -0.0018 -0.0077 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P22 compound treatment 5.83257075E8 7190000.0 0.11 5.68190194E8 2.2E7 0.5 0.4303 0.8455 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P23 compound treatment 5.51581212E8 -2.45E7 -0.38 5.37865051E8 -8360000.0 -0.19 -0.4032 -0.9475 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2181 P24 compound treatment 5.72426724E8 -3640000.0 -0.06 5.54848489E8 8620000.0 0.19 0.0978 0.4818 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A01 compound treatment 5.76762507E8 1.0E7 0.16 5.81677463E8 2.14E7 0.48 0.4533 0.8901 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A02 compound treatment 6.20617392E8 5.39E7 0.84 6.2852821E8 6.83E7 1.54 1.685 0.959 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A03 compound treatment 5.94251984E8 2.75E7 0.43 5.71081464E8 1.08E7 0.25 0.4766 0.9648 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A04 compound treatment 6.01689953E8 3.5E7 0.54 6.17810945E8 5.76E7 1.3 1.3053 0.9253 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A05 compound treatment 5.69501471E8 2780000.0 0.04 5.93429662E8 3.32E7 0.75 0.5611 0.7467 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A06 compound treatment 5.76539962E8 9820000.0 0.15 5.56362241E8 -3870000.0 -0.09 0.0463 0.2626 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A07 compound treatment 5.8380756E8 1.71E7 0.27 5.46422816E8 -1.38E7 -0.31 -0.0325 -0.0793 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A08 compound treatment 5.88322478E8 2.16E7 0.34 5.90646243E8 3.04E7 0.69 0.7239 0.946 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A09 compound treatment 5.87162638E8 2.04E7 0.32 5.60113339E8 -120000.0 0.0 0.2232 0.7011 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A10 compound treatment 5.66807771E8 85500.0 0.0 5.80378644E8 2.01E7 0.46 0.3229 0.7092 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A11 compound treatment 5.6057553E8 -6150000.0 -0.1 5.60652949E8 420000.0 0.01 -0.061 -0.634 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A12 compound treatment 5.82853925E8 1.61E7 0.25 5.6215921E8 1930000.0 0.04 0.2084 0.8174 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A13 mock treatment 5.5643706E8 -1.03E7 -0.16 5.31961888E8 -2.83E7 -0.64 -0.5651 -0.8578 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A14 mock treatment 5.6515481E8 -1570000.0 -0.02 5.4826713E8 -1.2E7 -0.27 -0.2085 -0.7678 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A15 compound treatment 5.48732224E8 -1.8E7 -0.28 5.49503272E8 -1.07E7 -0.24 -0.3696 -0.9974 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A16 compound treatment 5.50466798E8 -1.63E7 -0.25 5.61741454E8 1510000.0 0.03 -0.1549 -0.6065 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A17 compound treatment 4.87280431E8 -7.94E7 -1.24 4.79903708E8 -8.03E7 -1.82 -2.1587 -0.9825 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A18 compound treatment 5.41052578E8 -2.57E7 -0.4 5.42566873E8 -1.77E7 -0.4 -0.565 -1.0 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A19 compound treatment 5.38210847E8 -2.85E7 -0.44 5.38953139E8 -2.13E7 -0.48 -0.6541 -0.9992 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A20 compound treatment 5.43492322E8 -2.32E7 -0.36 5.30776612E8 -2.95E7 -0.67 -0.7266 -0.9589 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A21 compound treatment 5.39531091E8 -2.72E7 -0.42 5.32227322E8 -2.8E7 -0.63 -0.747 -0.9809 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A22 compound treatment 5.63086723E8 -3640000.0 -0.06 5.56289224E8 -3940000.0 -0.09 -0.1031 -0.976 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A23 compound treatment 5.2856691E8 -3.82E7 -0.59 5.29545038E8 -3.07E7 -0.69 -0.9107 -0.997 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 A24 compound treatment 5.34727576E8 -3.2E7 -0.5 5.43707459E8 -1.65E7 -0.37 -0.6165 -0.9899 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B01 compound treatment 5.11049696E8 -5.57E7 -0.87 5.11707341E8 -4.85E7 -1.1 -1.3886 -0.9932 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B02 compound treatment 5.09293616E8 -5.74E7 -0.89 5.28997209E8 -3.12E7 -0.71 -1.1317 -0.9931 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B03 compound treatment 5.62499065E8 -4220000.0 -0.07 5.6217075E8 1940000.0 0.04 -0.0156 -0.1968 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B04 compound treatment 5.36819498E8 -2.99E7 -0.47 5.54125251E8 -6110000.0 -0.14 -0.427 -0.8789 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B05 compound treatment 5.59255001E8 -7470000.0 -0.12 5.75593138E8 1.54E7 0.35 0.1632 0.4458 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B06 compound treatment 5.49397371E8 -1.73E7 -0.27 5.3644999E8 -2.38E7 -0.54 -0.5709 -0.9492 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B07 compound treatment 5.61872213E8 -4850000.0 -0.08 5.45912602E8 -1.43E7 -0.32 -0.2823 -0.8493 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B08 compound treatment 5.4486085E8 -2.19E7 -0.34 5.25778026E8 -3.45E7 -0.78 -0.7914 -0.9312 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B09 compound treatment 5.36465301E8 -3.03E7 -0.47 5.40854311E8 -1.94E7 -0.44 -0.6429 -0.9993 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B10 compound treatment 5.4167851E8 -2.5E7 -0.39 5.33600474E8 -2.66E7 -0.6 -0.7014 -0.978 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B11 compound treatment 5.4076895E8 -2.6E7 -0.4 5.53627307E8 -6610000.0 -0.15 -0.3914 -0.9083 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B12 compound treatment 5.17479958E8 -4.92E7 -0.77 5.40038924E8 -2.02E7 -0.46 -0.8651 -0.9692 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B13 mock treatment 5.60285471E8 -6440000.0 -0.1 5.52027968E8 -8210000.0 -0.19 -0.202 -0.9583 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B14 mock treatment 5.42988338E8 -2.37E7 -0.37 5.58507697E8 -1730000.0 -0.04 -0.289 -0.7774 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B15 compound treatment 5.43512889E8 -2.32E7 -0.36 5.4811675E8 -1.21E7 -0.27 -0.4493 -0.9906 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B16 compound treatment 5.25390095E8 -4.13E7 -0.64 5.34853952E8 -2.54E7 -0.57 -0.8608 -0.9983 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B17 compound treatment 5.36575784E8 -3.01E7 -0.47 5.60592831E8 359000.0 0.01 -0.3263 -0.6948 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B18 compound treatment 5.17204529E8 -4.95E7 -0.77 5.2075473E8 -3.95E7 -0.89 -1.1763 -0.9974 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B19 compound treatment 5.35532537E8 -3.12E7 -0.49 5.30271697E8 -3.0E7 -0.68 -0.8223 -0.9867 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B20 compound treatment 4.9941737E8 -6.73E7 -1.05 5.06761925E8 -5.35E7 -1.21 -1.5958 -0.9975 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B21 compound treatment 5.65278033E8 -1440000.0 -0.02 5.55334614E8 -4900000.0 -0.11 -0.0942 -0.8337 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B22 compound treatment 5.20288299E8 -4.64E7 -0.72 5.31401283E8 -2.88E7 -0.65 -0.9722 -0.9986 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B23 compound treatment 5.80305604E8 1.36E7 0.21 5.50246015E8 -9990000.0 -0.23 -0.01 -0.0323 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 B24 compound treatment 5.1173727E8 -5.5E7 -0.86 5.00212068E8 -6.0E7 -1.36 -1.5648 -0.9754 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C01 compound treatment 6.38751277E8 7.2E7 1.12 5.91362892E8 3.11E7 0.7 1.2908 0.9747 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C02 compound treatment 6.00158724E8 3.34E7 0.52 5.85000509E8 2.48E7 0.56 0.7641 0.9994 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C03 compound treatment 5.9703465E8 3.03E7 0.47 5.9619756E8 3.6E7 0.81 0.9086 0.9666 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C04 compound treatment 5.95469769E8 2.87E7 0.45 5.9304395E8 3.28E7 0.74 0.841 0.9708 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C05 compound treatment 5.75431604E8 8710000.0 0.14 5.37317246E8 -2.29E7 -0.52 -0.2703 -0.5049 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C06 compound treatment 5.98618904E8 3.19E7 0.5 5.89666458E8 2.94E7 0.67 0.8217 0.9897 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C07 compound treatment 5.80292309E8 1.36E7 0.21 5.58140422E8 -2090000.0 -0.05 0.116 0.5356 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C08 compound treatment 6.15764033E8 4.9E7 0.76 5.96876157E8 3.66E7 0.83 1.1257 0.9992 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C09 compound treatment 5.48270167E8 -1.85E7 -0.29 5.82659348E8 2.24E7 0.51 0.1552 0.2663 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C10 compound treatment 5.73234846E8 6510000.0 0.1 5.77020051E8 1.68E7 0.38 0.34 0.8658 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C11 mock treatment 5.89530379E8 2.28E7 0.36 5.97167665E8 3.69E7 0.83 0.8414 0.9275 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C12 mock treatment 5.86979799E8 2.03E7 0.32 5.93255634E8 3.3E7 0.75 0.7508 0.9266 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C13 compound treatment 5.78193948E8 1.15E7 0.18 5.63098378E8 2870000.0 0.06 0.1721 0.9057 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C14 compound treatment 5.99667009E8 3.29E7 0.51 5.98186097E8 3.8E7 0.86 0.9694 0.9698 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C15 mock treatment 6.32147132E8 6.54E7 1.02 5.97887184E8 3.77E7 0.85 1.3223 0.996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C16 mock treatment 6.00242612E8 3.35E7 0.52 5.8378376E8 2.36E7 0.53 0.7455 1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C17 compound treatment 6.16172109E8 4.94E7 0.77 5.98788741E8 3.86E7 0.87 1.1608 0.9981 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C18 compound treatment 5.44975101E8 -2.17E7 -0.34 5.21672638E8 -3.86E7 -0.87 -0.8557 -0.9152 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C19 compound treatment 5.41333267E8 -2.54E7 -0.4 5.36147176E8 -2.41E7 -0.54 -0.6645 -0.9877 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C20 compound treatment 5.98724468E8 3.2E7 0.5 5.62473123E8 2240000.0 0.05 0.3883 0.7749 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C21 compound treatment 6.0780704E8 4.11E7 0.64 5.60674205E8 441000.0 0.01 0.4595 0.718 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C22 compound treatment 5.97194808E8 3.05E7 0.47 5.68141591E8 7910000.0 0.18 0.462 0.9109 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C23 compound treatment 5.80094104E8 1.34E7 0.21 5.69264437E8 9030000.0 0.2 0.2916 0.9999 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 C24 compound treatment 5.66659719E8 -62500.0 0.0 5.38009982E8 -2.22E7 -0.5 -0.3558 -0.7085 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D01 compound treatment 5.90255895E8 2.35E7 0.37 6.11600032E8 5.14E7 1.16 1.0801 0.8872 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D02 compound treatment 5.38274309E8 -2.84E7 -0.44 5.4833663E8 -1.19E7 -0.27 -0.5034 -0.9713 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D03 compound treatment 5.88457982E8 2.17E7 0.34 5.86310117E8 2.61E7 0.59 0.6561 0.9654 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D04 compound treatment 5.97426786E8 3.07E7 0.48 5.90595267E8 3.04E7 0.69 0.8234 0.9844 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D05 compound treatment 5.91275459E8 2.46E7 0.38 6.22797802E8 6.26E7 1.41 1.2702 0.8672 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D06 compound treatment 5.97042648E8 3.03E7 0.47 5.5977936E8 -454000.0 -0.01 0.3267 0.6916 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D07 compound treatment 6.11727002E8 4.5E7 0.7 5.9961488E8 3.94E7 0.89 1.125 0.993 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D08 compound treatment 6.02344514E8 3.56E7 0.55 5.56220919E8 -4010000.0 -0.09 0.3282 0.5838 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D09 compound treatment 6.19337474E8 5.26E7 0.82 5.70890175E8 1.07E7 0.24 0.7498 0.8778 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D10 compound treatment 6.07252229E8 4.05E7 0.63 5.68526494E8 8290000.0 0.19 0.5789 0.8791 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D11 mock treatment 6.05644051E8 3.89E7 0.61 5.86215849E8 2.6E7 0.59 0.8439 0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D12 mock treatment 5.99635931E8 3.29E7 0.51 5.93663236E8 3.34E7 0.76 0.8967 0.9822 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D13 compound treatment 6.02576184E8 3.59E7 0.56 5.60067421E8 -166000.0 0.0 0.3922 0.7023 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D14 compound treatment 5.87225059E8 2.05E7 0.32 5.64871716E8 4640000.0 0.1 0.2999 0.8924 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D15 mock treatment 6.04412071E8 3.77E7 0.59 5.9231706E8 3.21E7 0.73 0.9278 0.9945 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D16 mock treatment 5.98344906E8 3.16E7 0.49 5.78955199E8 1.87E7 0.42 0.6475 0.9971 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D17 compound treatment 6.05262707E8 3.85E7 0.6 5.65759004E8 5530000.0 0.12 0.5128 0.8363 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D18 compound treatment 5.7452924E8 7810000.0 0.12 5.57981637E8 -2250000.0 -0.05 0.05 0.3793 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D19 compound treatment 6.0167115E8 3.49E7 0.54 5.83017754E8 2.28E7 0.51 0.749 0.9996 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D20 compound treatment 5.85089661E8 1.84E7 0.29 5.6596841E8 5740000.0 0.13 0.2939 0.9359 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D21 compound treatment 5.93225648E8 2.65E7 0.41 5.65593254E8 5360000.0 0.12 0.3776 0.8776 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D22 compound treatment 5.53118272E8 -1.36E7 -0.21 5.62226067E8 1990000.0 0.05 -0.118 -0.5447 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D23 compound treatment 5.83573902E8 1.69E7 0.26 5.64763863E8 4530000.0 0.1 0.258 0.9157 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 D24 compound treatment 5.89443827E8 2.27E7 0.35 5.75335802E8 1.51E7 0.34 0.4916 0.9998 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E01 mock treatment 5.46945481E8 -1.98E7 -0.31 5.29515678E8 -3.07E7 -0.69 -0.7087 -0.9331 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E02 mock treatment 5.18328656E8 -4.84E7 -0.75 5.07650244E8 -5.26E7 -1.19 -1.3733 -0.9759 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E03 mock treatment 5.39475003E8 -2.72E7 -0.42 5.07714999E8 -5.25E7 -1.19 -1.1394 -0.9039 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E04 compound treatment 5.24275999E8 -4.24E7 -0.66 5.29317978E8 -3.09E7 -0.7 -0.9615 -0.9996 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E05 compound treatment 5.26226047E8 -4.05E7 -0.63 5.25948988E8 -3.43E7 -0.77 -0.9939 -0.9948 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E06 compound treatment 5.35507004E8 -3.12E7 -0.49 5.32041528E8 -2.82E7 -0.64 -0.7943 -0.9911 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E07 compound treatment 5.62731815E8 -3990000.0 -0.06 5.36292507E8 -2.39E7 -0.54 -0.4265 -0.7832 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E08 compound treatment 4.68595323E8 -9.81E7 -1.53 4.74746511E8 -8.55E7 -1.93 -2.4469 -0.9933 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E09 mock treatment 5.701101E8 3390000.0 0.05 5.24606463E8 -3.56E7 -0.81 -0.532 -0.6593 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E10 mock treatment 5.45303822E8 -2.14E7 -0.33 5.21734588E8 -3.85E7 -0.87 -0.8511 -0.9134 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E11 compound treatment 5.47952173E8 -1.88E7 -0.29 5.04724267E8 -5.55E7 -1.25 -1.0938 -0.8491 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E12 compound treatment 5.37483039E8 -2.92E7 -0.46 5.1774115E8 -4.25E7 -0.96 -1.0011 -0.9419 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E13 compound treatment 5.01470275E8 -6.53E7 -1.02 4.69089404E8 -9.11E7 -2.06 -2.1752 -0.947 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E14 compound treatment 5.49487142E8 -1.72E7 -0.27 5.17851119E8 -4.24E7 -0.96 -0.8671 -0.8717 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E15 compound treatment 5.31668577E8 -3.51E7 -0.55 5.05634378E8 -5.46E7 -1.23 -1.2586 -0.9328 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E16 compound treatment 5.45529323E8 -2.12E7 -0.33 5.2397493E8 -3.63E7 -0.82 -0.8128 -0.9201 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E17 mock treatment 5.49872916E8 -1.68E7 -0.26 5.1778719E8 -4.24E7 -0.96 -0.8639 -0.8686 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E18 mock treatment 5.3632409E8 -3.04E7 -0.47 5.29212766E8 -3.1E7 -0.7 -0.8305 -0.9817 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E19 compound treatment 5.02721321E8 -6.4E7 -1.0 4.75511271E8 -8.47E7 -1.91 -2.0588 -0.9537 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E20 compound treatment 5.36777621E8 -2.99E7 -0.47 5.05010605E8 -5.52E7 -1.25 -1.2123 -0.9099 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E21 compound treatment 5.38276222E8 -2.84E7 -0.44 5.00819447E8 -5.94E7 -1.34 -1.2628 -0.8931 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E22 compound treatment 5.48450361E8 -1.83E7 -0.28 5.31905735E8 -2.83E7 -0.64 -0.6539 -0.9334 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E23 compound treatment 5.2458665E8 -4.21E7 -0.66 5.15011534E8 -4.52E7 -1.02 -1.1868 -0.9771 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 E24 compound treatment 5.33984879E8 -3.27E7 -0.51 5.03960888E8 -5.63E7 -1.27 -1.2598 -0.9195 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F01 mock treatment 5.3474778E8 -3.2E7 -0.5 5.3230597E8 -2.79E7 -0.63 -0.7985 -0.9931 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F02 mock treatment 5.75935064E8 9210000.0 0.14 5.33505735E8 -2.67E7 -0.6 -0.3257 -0.5245 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F03 compound treatment 5.45333261E8 -2.14E7 -0.33 5.30226681E8 -3.0E7 -0.68 -0.7151 -0.9464 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F04 compound treatment 5.20173618E8 -4.65E7 -0.73 5.26530689E8 -3.37E7 -0.76 -1.0513 -0.9997 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F05 compound treatment 5.7833972E8 1.16E7 0.18 5.57959365E8 -2270000.0 -0.05 0.0916 0.487 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F06 compound treatment 5.54056209E8 -1.27E7 -0.2 5.43297214E8 -1.69E7 -0.38 -0.4102 -0.9525 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F07 compound treatment 5.34254751E8 -3.25E7 -0.51 5.3475339E8 -2.55E7 -0.58 -0.7648 -0.9979 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F08 compound treatment 5.21958313E8 -4.48E7 -0.7 5.28906902E8 -3.13E7 -0.71 -0.9936 -1.0 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F09 mock treatment 5.77170049E8 1.04E7 0.16 5.29833001E8 -3.04E7 -0.69 -0.3707 -0.5251 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F10 mock treatment 5.46948982E8 -1.98E7 -0.31 5.23391716E8 -3.68E7 -0.83 -0.8065 -0.9085 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F11 compound treatment 5.29142454E8 -3.76E7 -0.59 5.12073529E8 -4.82E7 -1.09 -1.1835 -0.9577 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F12 compound treatment 5.27176218E8 -3.95E7 -0.62 5.35866676E8 -2.44E7 -0.55 -0.825 -0.9984 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F13 compound treatment 5.12780406E8 -5.39E7 -0.84 4.98177765E8 -6.21E7 -1.4 -1.5858 -0.97 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F14 compound treatment 5.37079367E8 -2.96E7 -0.46 5.24568536E8 -3.57E7 -0.81 -0.8964 -0.965 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F15 compound treatment 5.34679582E8 -3.2E7 -0.5 5.13171351E8 -4.71E7 -1.06 -1.105 -0.9405 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F16 compound treatment 5.40061174E8 -2.67E7 -0.42 5.20811168E8 -3.94E7 -0.89 -0.9236 -0.9396 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F17 mock treatment 5.59303786E8 -7420000.0 -0.12 5.55642206E8 -4590000.0 -0.1 -0.1551 -0.9986 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F18 mock treatment 5.52471616E8 -1.43E7 -0.22 5.3444381E8 -2.58E7 -0.58 -0.5691 -0.9125 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F19 compound treatment 5.29784747E8 -3.69E7 -0.58 5.38603026E8 -2.16E7 -0.49 -0.7525 -0.9967 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F20 compound treatment 5.14518604E8 -5.22E7 -0.81 4.81017202E8 -7.92E7 -1.79 -1.8409 -0.9362 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F21 compound treatment 5.1823299E8 -4.85E7 -0.76 5.10673521E8 -4.96E7 -1.12 -1.3261 -0.9816 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F22 compound treatment 5.05214341E8 -6.15E7 -0.96 4.78166001E8 -8.21E7 -1.85 -1.9889 -0.9528 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F23 compound treatment 5.29642966E8 -3.71E7 -0.58 5.06588771E8 -5.36E7 -1.21 -1.2657 -0.9425 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 F24 compound treatment 5.40455013E8 -2.63E7 -0.41 4.88234757E8 -7.2E7 -1.63 -1.4399 -0.8582 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G01 compound treatment 6.24511617E8 5.78E7 0.9 5.82334229E8 2.21E7 0.5 0.9897 0.9614 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G02 compound treatment 5.74633285E8 7910000.0 0.12 5.62723447E8 2490000.0 0.06 0.1269 0.937 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G03 mock treatment 6.0083103E8 3.41E7 0.53 6.01165215E8 4.09E7 0.93 1.0298 0.9653 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G04 mock treatment 5.8916661E8 2.24E7 0.35 5.77660297E8 1.74E7 0.39 0.5257 0.9982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G05 compound treatment 5.90953078E8 2.42E7 0.38 5.84894326E8 2.47E7 0.56 0.661 0.982 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G06 compound treatment 5.93870408E8 2.71E7 0.42 5.78564174E8 1.83E7 0.41 0.5919 0.9999 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G07 compound treatment 5.86881043E8 2.02E7 0.31 5.47878525E8 -1.24E7 -0.28 0.0246 0.0585 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G08 compound treatment 5.80904075E8 1.42E7 0.22 6.0604438E8 4.58E7 1.04 0.8883 0.8391 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G09 compound treatment 5.53992717E8 -1.27E7 -0.2 5.65521157E8 5290000.0 0.12 -0.0557 -0.2406 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G10 compound treatment 5.87397442E8 2.07E7 0.32 5.83837612E8 2.36E7 0.53 0.6049 0.9708 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G11 compound treatment 6.06257223E8 3.95E7 0.62 5.86538972E8 2.63E7 0.59 0.8558 0.9998 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G12 compound treatment 5.64387764E8 -2330000.0 -0.04 5.72881587E8 1.26E7 0.29 0.1764 0.6122 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G13 compound treatment 5.58070629E8 -8650000.0 -0.13 5.86405328E8 2.62E7 0.59 0.323 0.5324 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G14 compound treatment 5.63645748E8 -3080000.0 -0.05 5.72833283E8 1.26E7 0.28 0.1675 0.58 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G15 compound treatment 5.76022583E8 9300000.0 0.14 5.82296853E8 2.21E7 0.5 0.455 0.8763 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G16 compound treatment 5.85515583E8 1.88E7 0.29 5.58724036E8 -1510000.0 -0.03 0.1829 0.6205 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G17 compound treatment 5.69371345E8 2650000.0 0.04 5.56026222E8 -4210000.0 -0.1 -0.0381 -0.3672 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G18 compound treatment 5.96212347E8 2.95E7 0.46 5.59973448E8 -260000.0 -0.01 0.3206 0.698 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G19 mock treatment 5.86424458E8 1.97E7 0.31 5.7762304E8 1.74E7 0.39 0.4949 0.9925 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G20 mock treatment 6.09681972E8 4.3E7 0.67 5.83326143E8 2.31E7 0.52 0.8422 0.9924 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G21 compound treatment 5.79703999E8 1.3E7 0.2 5.67774215E8 7540000.0 0.17 0.2635 0.9964 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G22 compound treatment 5.7653789E8 9820000.0 0.15 5.78242545E8 1.8E7 0.41 0.3959 0.9106 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G23 compound treatment 5.29483758E8 -3.72E7 -0.58 5.355284E8 -2.47E7 -0.56 -0.8049 -0.9998 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 G24 compound treatment 5.65351595E8 -1370000.0 -0.02 5.46035889E8 -1.42E7 -0.32 -0.242 -0.7525 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H01 compound treatment 5.60222487E8 -6500000.0 -0.1 5.85243716E8 2.5E7 0.57 0.3281 0.5714 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H02 compound treatment 6.02876719E8 3.62E7 0.56 5.86361107E8 2.61E7 0.59 0.8157 0.9997 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H03 mock treatment 6.10642822E8 4.39E7 0.68 5.76630563E8 1.64E7 0.37 0.7458 0.9585 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H04 mock treatment 6.31971476E8 6.52E7 1.02 5.80883125E8 2.06E7 0.47 1.0486 0.9377 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H05 compound treatment 6.26055924E8 5.93E7 0.92 6.10466915E8 5.02E7 1.14 1.4563 0.9948 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H06 compound treatment 6.10120036E8 4.34E7 0.68 5.66557632E8 6320000.0 0.14 0.579 0.8381 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H07 compound treatment 6.03586795E8 3.69E7 0.57 6.23140191E8 6.29E7 1.42 1.4113 0.9205 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H08 compound treatment 6.06805716E8 4.01E7 0.62 6.24577797E8 6.43E7 1.45 1.4697 0.9287 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H09 compound treatment 6.08480589E8 4.18E7 0.65 6.0997326E8 4.97E7 1.12 1.2548 0.9662 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H10 compound treatment 5.89171852E8 2.24E7 0.35 5.80680659E8 2.04E7 0.46 0.574 0.9905 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H11 compound treatment 5.95151279E8 2.84E7 0.44 5.91959784E8 3.17E7 0.72 0.8201 0.9732 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H12 compound treatment 5.76343769E8 9620000.0 0.15 5.87838783E8 2.76E7 0.62 0.5471 0.8527 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H13 compound treatment 5.71411898E8 4690000.0 0.07 5.76870128E8 1.66E7 0.38 0.3175 0.829 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H14 compound treatment 6.07487408E8 4.08E7 0.63 5.84824981E8 2.46E7 0.56 0.842 0.9978 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H15 compound treatment 5.80895348E8 1.42E7 0.22 5.78791296E8 1.86E7 0.42 0.4527 0.9551 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H16 compound treatment 5.90260883E8 2.35E7 0.37 6.00733368E8 4.05E7 0.92 0.9065 0.9193 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H17 compound treatment 5.98625025E8 3.19E7 0.5 5.81710876E8 2.15E7 0.49 0.6946 0.9999 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H18 compound treatment 6.09245571E8 4.25E7 0.66 5.80828534E8 2.06E7 0.47 0.7975 0.9851 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H19 mock treatment 6.27722521E8 6.1E7 0.95 5.69031108E8 8800000.0 0.2 0.8124 0.8369 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H20 mock treatment 6.06966085E8 4.02E7 0.63 6.01725115E8 4.15E7 0.94 1.1063 0.9808 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H21 compound treatment 5.72254842E8 5530000.0 0.09 5.4647106E8 -1.38E7 -0.31 -0.159 -0.4926 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H22 compound treatment 5.6025242E8 -6470000.0 -0.1 5.72980785E8 1.27E7 0.29 0.1325 0.434 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H23 compound treatment 5.66168718E8 -554000.0 -0.01 5.36391074E8 -2.38E7 -0.54 -0.3871 -0.7183 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 H24 compound treatment 5.71796428E8 5070000.0 0.08 5.13495597E8 -4.67E7 -1.06 -0.691 -0.6524 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I01 compound treatment 4.96674706E8 -7.0E7 -1.09 5.04497197E8 -5.57E7 -1.26 -1.6622 -0.9974 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I02 compound treatment 4.93249532E8 -7.35E7 -1.14 5.12018575E8 -4.82E7 -1.09 -1.5797 -0.9997 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I03 compound treatment 4.93839279E8 -7.29E7 -1.14 5.20409163E8 -3.98E7 -0.9 -1.4391 -0.9934 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I04 compound treatment 5.41348584E8 -2.54E7 -0.4 5.0090824E8 -5.93E7 -1.34 -1.2275 -0.8782 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I05 mock treatment 5.05944447E8 -6.08E7 -0.95 5.24868021E8 -3.54E7 -0.8 -1.2346 -0.9965 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I06 mock treatment 5.27111387E8 -3.96E7 -0.62 5.27675425E8 -3.26E7 -0.74 -0.9566 -0.9962 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I07 compound treatment 5.07214192E8 -5.95E7 -0.93 5.28290972E8 -3.19E7 -0.72 -1.1659 -0.9924 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I08 compound treatment 5.40550493E8 -2.62E7 -0.41 5.45011305E8 -1.52E7 -0.34 -0.5315 -0.9964 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I09 compound treatment 5.09316597E8 -5.74E7 -0.89 5.70706843E8 1.05E7 0.24 -0.4649 -0.5026 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I10 compound treatment 5.03742534E8 -6.3E7 -0.98 5.25943423E8 -3.43E7 -0.77 -1.2416 -0.9932 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I11 compound treatment 3.93513738E8 -1.73E8 -2.7 4.14053063E8 -1.46E8 -3.3 -4.2438 -0.9949 BCB03_000168 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I12 compound treatment 5.36587476E8 -3.01E7 -0.47 5.46689438E8 -1.35E7 -0.31 -0.5483 -0.9785 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I13 compound treatment 4.88684667E8 -7.8E7 -1.22 5.26310314E8 -3.39E7 -0.77 -1.4016 -0.9753 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I14 compound treatment 5.22499954E8 -4.42E7 -0.69 5.60986907E8 754000.0 0.02 -0.475 -0.6894 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I15 compound treatment 5.08024362E8 -5.87E7 -0.91 5.40794422E8 -1.94E7 -0.44 -0.9571 -0.9436 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I16 compound treatment 5.13970372E8 -5.28E7 -0.82 5.45073401E8 -1.52E7 -0.34 -0.8233 -0.9248 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I17 compound treatment 5.02779868E8 -6.39E7 -1.0 5.25741671E8 -3.45E7 -0.78 -1.2555 -0.9927 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I18 compound treatment 4.96436176E8 -7.03E7 -1.09 5.80155775E8 1.99E7 0.45 -0.4557 -0.385 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I19 compound treatment 4.92860277E8 -7.39E7 -1.15 5.24515405E8 -3.57E7 -0.81 -1.3843 -0.985 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I20 compound treatment 4.98207052E8 -6.85E7 -1.07 5.47429533E8 -1.28E7 -0.29 -0.9592 -0.8675 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I21 mock treatment 5.11157916E8 -5.56E7 -0.87 5.3407442E8 -2.62E7 -0.59 -1.03 -0.9827 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I22 mock treatment 4.99457731E8 -6.73E7 -1.05 5.47208278E8 -1.3E7 -0.29 -0.949 -0.872 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I23 compound treatment 4.90254376E8 -7.65E7 -1.19 5.50866582E8 -9370000.0 -0.21 -0.9919 -0.8199 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 I24 compound treatment 4.79871435E8 -8.69E7 -1.35 5.23194284E8 -3.7E7 -0.84 -1.5485 -0.9734 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J01 compound treatment 5.32160279E8 -3.46E7 -0.54 5.44765409E8 -1.55E7 -0.35 -0.6278 -0.9781 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J02 compound treatment 5.11296825E8 -5.54E7 -0.86 5.3538789E8 -2.48E7 -0.56 -1.0075 -0.9783 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J03 compound treatment 5.30153342E8 -3.66E7 -0.57 5.97483721E8 3.73E7 0.84 0.1925 0.1894 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J04 compound treatment 5.20669054E8 -4.61E7 -0.72 5.4064717E8 -1.96E7 -0.44 -0.8202 -0.9731 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J05 mock treatment 5.6300646E8 -3720000.0 -0.06 5.96466645E8 3.62E7 0.82 0.5381 0.6555 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J06 mock treatment 5.16344898E8 -5.04E7 -0.78 5.95244463E8 3.5E7 0.79 0.0047 0.0042 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J07 compound treatment 5.41522889E8 -2.52E7 -0.39 5.75470257E8 1.52E7 0.34 -0.034 -0.0652 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J08 compound treatment 5.04038556E8 -6.27E7 -0.98 5.32578435E8 -2.77E7 -0.63 -1.1323 -0.9768 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J09 compound treatment 5.05628738E8 -6.11E7 -0.95 5.39630577E8 -2.06E7 -0.47 -1.0021 -0.9459 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J10 compound treatment 5.01876716E8 -6.48E7 -1.01 5.60951808E8 718000.0 0.02 -0.7027 -0.6956 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J11 compound treatment 5.11858962E8 -5.49E7 -0.85 5.16938707E8 -4.33E7 -0.98 -1.2961 -0.9977 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J12 compound treatment 5.09713832E8 -5.7E7 -0.89 5.59510396E8 -723000.0 -0.02 -0.6394 -0.72 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J13 compound treatment 4.43843179E8 -1.23E8 -1.91 5.55882576E8 -4350000.0 -0.1 -1.4229 -0.7425 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J14 compound treatment 4.7336211E8 -9.34E7 -1.45 5.63560327E8 3330000.0 0.08 -0.9751 -0.6697 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J15 compound treatment 4.34665891E8 -1.32E8 -2.06 5.31620655E8 -2.86E7 -0.65 -1.9117 -0.8866 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J16 compound treatment 4.76157075E8 -9.06E7 -1.41 5.73057746E8 1.28E7 0.29 -0.7925 -0.5503 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J17 compound treatment 4.980703E8 -6.87E7 -1.07 5.42311253E8 -1.79E7 -0.41 -1.0425 -0.9117 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J18 compound treatment 4.88988541E8 -7.77E7 -1.21 5.50246061E8 -9990000.0 -0.23 -1.0158 -0.8247 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J19 compound treatment 4.58214589E8 -1.09E8 -1.69 5.61413687E8 1180000.0 0.03 -1.1762 -0.6959 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J20 compound treatment 4.42473518E8 -1.24E8 -1.94 5.3639777E8 -2.38E7 -0.54 -1.7494 -0.8708 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J21 mock treatment 5.05972451E8 -6.07E7 -0.95 5.37917834E8 -2.23E7 -0.5 -1.0257 -0.9566 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J22 mock treatment 4.85907157E8 -8.08E7 -1.26 5.52778482E8 -7450000.0 -0.17 -1.0092 -0.7947 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J23 compound treatment 4.69789221E8 -9.69E7 -1.51 5.43627296E8 -1.66E7 -0.38 -1.333 -0.8568 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 J24 compound treatment 4.32237267E8 -1.34E8 -2.09 4.88632809E8 -7.16E7 -1.62 -2.6254 -0.9919 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K01 compound treatment 5.72676431E8 5950000.0 0.09 5.62051042E8 1820000.0 0.04 0.0946 0.9329 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K02 compound treatment 5.60156798E8 -6570000.0 -0.1 5.47294955E8 -1.29E7 -0.29 -0.2791 -0.9009 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K03 compound treatment 5.42702265E8 -2.4E7 -0.37 5.43336501E8 -1.69E7 -0.38 -0.5346 -0.9999 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K04 compound treatment 5.57296049E8 -9430000.0 -0.15 5.61422749E8 1190000.0 0.03 -0.0848 -0.5682 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K05 compound treatment 5.58183363E8 -8540000.0 -0.13 5.47970859E8 -1.23E7 -0.28 -0.29 -0.9434 1107217 BCB03_000204 Cc1cccnc1I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K06 compound treatment 5.62436626E8 -4290000.0 -0.07 5.7321611E8 1.3E7 0.29 0.1603 0.5326 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K07 mock treatment 5.67709308E8 987000.0 0.02 5.83253083E8 2.3E7 0.52 0.3787 0.7277 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K08 mock treatment 5.75707463E8 8990000.0 0.14 5.86428817E8 2.62E7 0.59 0.5176 0.8508 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K09 compound treatment 5.79201007E8 1.25E7 0.19 5.60632846E8 399000.0 0.01 0.1438 0.7392 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K10 compound treatment 5.6675143E8 29200.0 0.0 5.52034018E8 -8200000.0 -0.19 -0.1307 -0.7054 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K11 compound treatment 5.59753904E8 -6970000.0 -0.11 5.42729095E8 -1.75E7 -0.4 -0.3565 -0.869 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K12 compound treatment 5.53605252E8 -1.31E7 -0.2 5.37621709E8 -2.26E7 -0.51 -0.5058 -0.9191 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K13 compound treatment 5.40865779E8 -2.59E7 -0.4 5.46185904E8 -1.4E7 -0.32 -0.5093 -0.9931 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K14 compound treatment 5.53969026E8 -1.28E7 -0.2 5.58588453E8 -1640000.0 -0.04 -0.1667 -0.8251 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K15 mock treatment 5.50346254E8 -1.64E7 -0.26 5.62976572E8 2740000.0 0.06 -0.1365 -0.5201 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K16 mock treatment 5.72606005E8 5880000.0 0.09 5.54260748E8 -5970000.0 -0.13 -0.0306 -0.1878 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K17 compound treatment 5.57065594E8 -9660000.0 -0.15 5.55161382E8 -5070000.0 -0.11 -0.1874 -0.991 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K18 compound treatment 5.46465657E8 -2.03E7 -0.32 5.38085582E8 -2.21E7 -0.5 -0.577 -0.9752 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K19 compound treatment 5.12171395E8 -5.46E7 -0.85 5.13503469E8 -4.67E7 -1.06 -1.3476 -0.9942 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K20 compound treatment 5.35155783E8 -3.16E7 -0.49 5.64229839E8 4000000.0 0.09 -0.2838 -0.5677 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K21 compound treatment 5.25366209E8 -4.14E7 -0.64 5.2131226E8 -3.89E7 -0.88 -1.0775 -0.9883 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K22 compound treatment 5.48117078E8 -1.86E7 -0.29 5.42304852E8 -1.79E7 -0.41 -0.4914 -0.9865 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K23 mock treatment 5.63998233E8 -2720000.0 -0.04 5.54857267E8 -5380000.0 -0.12 -0.1159 -0.9007 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 K24 mock treatment 5.50996959E8 -1.57E7 -0.24 5.58270693E8 -1960000.0 -0.04 -0.2046 -0.8218 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L01 compound treatment 6.11072891E8 4.44E7 0.69 5.85215703E8 2.5E7 0.56 0.8877 0.995 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L02 compound treatment 5.51676349E8 -1.5E7 -0.23 5.36159347E8 -2.41E7 -0.54 -0.5504 -0.9292 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L03 compound treatment 6.48902348E8 8.22E7 1.28 5.71936386E8 1.17E7 0.26 1.0921 0.8356 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L04 compound treatment 5.67828611E8 1110000.0 0.02 5.54801777E8 -5430000.0 -0.12 -0.0746 -0.6019 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L05 compound treatment 5.9002174E8 2.33E7 0.36 5.69837951E8 9600000.0 0.22 0.4101 0.9698 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L06 compound treatment 5.47143494E8 -1.96E7 -0.3 5.45301364E8 -1.49E7 -0.34 -0.4543 -0.9987 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L07 mock treatment 5.91517706E8 2.48E7 0.39 6.06782614E8 4.65E7 1.05 1.017 0.9075 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L08 mock treatment 5.85590531E8 1.89E7 0.29 5.76659418E8 1.64E7 0.37 0.4703 0.9933 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L09 compound treatment 5.67419971E8 698000.0 0.01 5.66951631E8 6720000.0 0.15 0.115 0.7558 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L10 compound treatment 5.3777242E8 -2.89E7 -0.45 5.30921202E8 -2.93E7 -0.66 -0.7873 -0.9824 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L11 compound treatment 5.8388756E8 1.72E7 0.27 5.84480978E8 2.42E7 0.55 0.5766 0.9456 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L12 compound treatment 5.37233723E8 -2.95E7 -0.46 5.28259703E8 -3.2E7 -0.72 -0.8357 -0.9761 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L13 compound treatment 5.83669625E8 1.69E7 0.26 5.32498948E8 -2.77E7 -0.63 -0.2566 -0.3772 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L14 compound treatment 5.52814401E8 -1.39E7 -0.22 5.27698971E8 -3.25E7 -0.74 -0.6731 -0.8781 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L15 mock treatment 5.60905548E8 -5820000.0 -0.09 5.84410128E8 2.42E7 0.55 0.3223 0.5819 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L16 mock treatment 5.96894271E8 3.02E7 0.47 5.82999664E8 2.28E7 0.51 0.6961 0.999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L17 compound treatment 5.52383819E8 -1.43E7 -0.22 5.56016477E8 -4220000.0 -0.1 -0.2253 -0.9279 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L18 compound treatment 5.32317344E8 -3.44E7 -0.54 5.32288669E8 -2.79E7 -0.63 -0.8255 -0.9967 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L19 compound treatment 5.79219683E8 1.25E7 0.19 5.65962595E8 5730000.0 0.13 0.2292 0.9804 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L20 compound treatment 5.30273358E8 -3.64E7 -0.57 5.46692149E8 -1.35E7 -0.31 -0.6178 -0.958 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L21 compound treatment 5.66216282E8 -506000.0 -0.01 5.61229952E8 997000.0 0.02 0.0104 0.4339 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L22 compound treatment 5.03369984E8 -6.34E7 -0.99 5.22863399E8 -3.74E7 -0.84 -1.295 -0.997 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L23 mock treatment 5.82714721E8 1.6E7 0.25 5.7153391E8 1.13E7 0.26 0.3567 0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 L24 mock treatment 5.48075199E8 -1.86E7 -0.29 5.52545162E8 -7690000.0 -0.17 -0.3282 -0.9698 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M01 compound treatment 5.24193989E8 -4.25E7 -0.66 4.8614648E8 -7.41E7 -1.67 -1.6524 -0.9177 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M02 compound treatment 5.65111031E8 -1610000.0 -0.03 5.17140477E8 -4.31E7 -0.97 -0.7064 -0.7251 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M03 compound treatment 5.84783765E8 1.81E7 0.28 5.21543561E8 -3.87E7 -0.87 -0.4194 -0.4566 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M04 compound treatment 5.69831156E8 3110000.0 0.05 5.70248462E8 1.0E7 0.23 0.1943 0.8394 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M05 compound treatment 5.68468601E8 1750000.0 0.03 5.48431456E8 -1.18E7 -0.27 -0.1694 -0.6317 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M06 compound treatment 5.77146945E8 1.04E7 0.16 5.49060673E8 -1.12E7 -0.25 -0.0637 -0.2123 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M07 compound treatment 5.47210962E8 -1.95E7 -0.3 5.56988302E8 -3250000.0 -0.07 -0.2668 -0.8533 3000956 BCB03_000242 CCCc1cccc(=O)o1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M08 compound treatment 5.5852059E8 -8200000.0 -0.13 5.45801069E8 -1.44E7 -0.33 -0.321 -0.9163 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M09 mock treatment 5.76960047E8 1.02E7 0.16 5.44964239E8 -1.53E7 -0.35 -0.1313 -0.3453 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M10 mock treatment 5.59841675E8 -6880000.0 -0.11 5.53257019E8 -6980000.0 -0.16 -0.1873 -0.9823 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M11 compound treatment 5.55233063E8 -1.15E7 -0.18 5.2375539E8 -3.65E7 -0.82 -0.7095 -0.841 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M12 compound treatment 5.66362636E8 -360000.0 -0.01 5.47988037E8 -1.22E7 -0.28 -0.1996 -0.7213 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M13 mock treatment 5.387327E8 -2.8E7 -0.44 5.53694705E8 -6540000.0 -0.15 -0.4128 -0.8967 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M14 mock treatment 5.44053056E8 -2.27E7 -0.35 5.29569936E8 -3.07E7 -0.69 -0.7397 -0.9511 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M15 compound treatment 5.34542981E8 -3.22E7 -0.5 5.19572012E8 -4.07E7 -0.92 -1.0042 -0.9594 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M16 compound treatment 5.30055438E8 -3.67E7 -0.57 5.22336346E8 -3.79E7 -0.86 -1.0095 -0.9806 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M17 compound treatment 5.33050741E8 -3.37E7 -0.52 5.44129199E8 -1.61E7 -0.36 -0.6282 -0.9841 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M18 compound treatment 5.28045076E8 -3.87E7 -0.6 5.33558386E8 -2.67E7 -0.6 -0.8523 -1.0 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M19 compound treatment 5.54845932E8 -1.19E7 -0.18 5.38905535E8 -2.13E7 -0.48 -0.4716 -0.9135 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M20 compound treatment 5.47919399E8 -1.88E7 -0.29 5.29112006E8 -3.11E7 -0.7 -0.7044 -0.9246 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M21 compound treatment 5.42820438E8 -2.39E7 -0.37 5.07416297E8 -5.28E7 -1.19 -1.1073 -0.8856 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M22 compound treatment 5.16228411E8 -5.05E7 -0.79 5.20096862E8 -4.01E7 -0.91 -1.1975 -0.9975 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M23 compound treatment 5.52417783E8 -1.43E7 -0.22 5.30300748E8 -2.99E7 -0.68 -0.6359 -0.8928 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 M24 compound treatment 5.10180365E8 -5.65E7 -0.88 4.96586342E8 -6.36E7 -1.44 -1.6399 -0.9723 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N01 compound treatment 5.30402731E8 -3.63E7 -0.57 5.06636593E8 -5.36E7 -1.21 -1.2565 -0.9399 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N02 compound treatment 5.36249663E8 -3.05E7 -0.47 5.13407394E8 -4.68E7 -1.06 -1.0839 -0.9346 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N03 compound treatment 5.48123352E8 -1.86E7 -0.29 4.91853823E8 -6.84E7 -1.55 -1.2976 -0.8253 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N04 compound treatment 5.57271252E8 -9450000.0 -0.15 5.2014736E8 -4.01E7 -0.91 -0.7447 -0.8114 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N05 compound treatment 5.43439131E8 -2.33E7 -0.36 5.2201092E8 -3.82E7 -0.86 -0.8673 -0.9257 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N06 compound treatment 5.14417811E8 -5.23E7 -0.81 5.1624792E8 -4.4E7 -0.99 -1.279 -0.9951 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N07 compound treatment 5.71198693E8 4480000.0 0.07 5.60589212E8 356000.0 0.01 0.055 0.7835 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N08 compound treatment 5.08985599E8 -5.77E7 -0.9 4.99773847E8 -6.05E7 -1.37 -1.6021 -0.9794 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N09 mock treatment 5.70874616E8 4150000.0 0.06 5.62419711E8 2190000.0 0.05 0.0807 0.9912 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N10 mock treatment 5.71804776E8 5080000.0 0.08 6.05426451E8 4.52E7 1.02 0.7782 0.7596 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N11 compound treatment 5.70682605E8 3960000.0 0.06 5.51719223E8 -8510000.0 -0.19 -0.0924 -0.4575 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N12 compound treatment 5.23460672E8 -4.33E7 -0.67 5.32043831E8 -2.82E7 -0.64 -0.927 -0.9996 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N13 mock treatment 5.67945889E8 1220000.0 0.02 5.41744925E8 -1.85E7 -0.42 -0.282 -0.6742 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N14 mock treatment 5.93477063E8 2.68E7 0.42 5.69746812E8 9510000.0 0.22 0.4467 0.9526 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N15 compound treatment 5.94447958E8 2.77E7 0.43 5.88033633E8 2.78E7 0.63 0.7496 0.9833 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N16 compound treatment 4.84967573E8 -8.18E7 -1.27 4.85400372E8 -7.48E7 -1.69 -2.0963 -0.9902 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N17 compound treatment 5.51469076E8 -1.53E7 -0.24 5.30625869E8 -2.96E7 -0.67 -0.6411 -0.9029 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N18 compound treatment 5.27403892E8 -3.93E7 -0.61 5.20223447E8 -4.0E7 -0.9 -1.0724 -0.982 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N19 compound treatment 5.65867525E8 -855000.0 -0.01 5.49821345E8 -1.04E7 -0.24 -0.1758 -0.7459 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N20 compound treatment 4.67999736E8 -9.87E7 -1.54 4.73769038E8 -8.65E7 -1.95 -2.4691 -0.993 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N21 compound treatment 5.37439667E8 -2.93E7 -0.46 5.36792476E8 -2.34E7 -0.53 -0.6971 -0.9972 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N22 compound treatment 4.0829885E8 -1.58E8 -2.47 3.58275766E8 -2.02E8 -4.56 -4.9723 -0.9583 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N23 compound treatment 5.30165596E8 -3.66E7 -0.57 5.22572627E8 -3.77E7 -0.85 -1.0045 -0.9809 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 N24 compound treatment 4.6562583E8 -1.01E8 -1.57 4.60752469E8 -9.95E7 -2.25 -2.7032 -0.9848 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O01 compound treatment 5.76970417E8 1.02E7 0.16 5.76957231E8 1.67E7 0.38 0.3801 0.9265 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O02 compound treatment 5.75344676E8 8620000.0 0.13 5.42435102E8 -1.78E7 -0.4 -0.1895 -0.4468 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O03 compound treatment 5.53935025E8 -1.28E7 -0.2 5.4803517E8 -1.22E7 -0.28 -0.3358 -0.9873 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O04 compound treatment 5.80911487E8 1.42E7 0.22 5.6311171E8 2880000.0 0.07 0.2023 0.878 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O05 compound treatment 5.55462444E8 -1.13E7 -0.18 5.55422096E8 -4810000.0 -0.11 -0.2009 -0.9736 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O06 compound treatment 5.76920254E8 1.02E7 0.16 5.69846149E8 9610000.0 0.22 0.2659 0.9882 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O07 compound treatment 5.71800075E8 5080000.0 0.08 5.37144513E8 -2.31E7 -0.52 -0.313 -0.5932 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O08 compound treatment 5.82186917E8 1.55E7 0.24 5.6836658E8 8130000.0 0.18 0.3003 0.9911 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O09 compound treatment 5.63703983E8 -3020000.0 -0.05 5.56149571E8 -4080000.0 -0.09 -0.0985 -0.951 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O10 compound treatment 5.33298021E8 -3.34E7 -0.52 5.26430918E8 -3.38E7 -0.76 -0.9083 -0.9825 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O11 mock treatment 5.52133707E8 -1.46E7 -0.23 5.55521885E8 -4710000.0 -0.11 -0.236 -0.9403 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O12 mock treatment 5.63071258E8 -3650000.0 -0.06 5.68331317E8 8100000.0 0.18 0.0892 0.4654 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O13 compound treatment 5.68428474E8 1710000.0 0.03 5.4901639E8 -1.12E7 -0.25 -0.1605 -0.6295 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O14 compound treatment 5.48111438E8 -1.86E7 -0.29 5.33626616E8 -2.66E7 -0.6 -0.6302 -0.944 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O15 compound treatment 5.53360956E8 -1.34E7 -0.21 5.46212514E8 -1.4E7 -0.32 -0.3712 -0.9792 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O16 compound treatment 5.6922932E8 2510000.0 0.04 5.52665516E8 -7570000.0 -0.17 -0.0933 -0.532 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O17 compound treatment 5.47828614E8 -1.89E7 -0.29 5.41695089E8 -1.85E7 -0.42 -0.5043 -0.9851 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O18 compound treatment 5.46355016E8 -2.04E7 -0.32 5.40722972E8 -1.95E7 -0.44 -0.5361 -0.987 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O19 compound treatment 5.56383293E8 -1.03E7 -0.16 5.43094361E8 -1.71E7 -0.39 -0.3878 -0.9244 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O20 compound treatment 5.52626269E8 -1.41E7 -0.22 5.53029418E8 -7200000.0 -0.16 -0.2704 -0.9892 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O21 compound treatment 5.45261984E8 -2.15E7 -0.33 5.40831903E8 -1.94E7 -0.44 -0.5464 -0.991 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O22 compound treatment 5.5244722E8 -1.43E7 -0.22 5.48308322E8 -1.19E7 -0.27 -0.3478 -0.9954 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O23 compound treatment 5.56828341E8 -9890000.0 -0.15 5.54684437E8 -5550000.0 -0.13 -0.1976 -0.9948 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 O24 compound treatment 5.46486073E8 -2.02E7 -0.32 5.34329215E8 -2.59E7 -0.59 -0.6368 -0.9578 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P01 compound treatment 5.65370282E8 -1350000.0 -0.02 5.85129955E8 2.49E7 0.56 0.383 0.6802 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P02 compound treatment 4.75700505E8 -9.1E7 -1.42 4.80600537E8 -7.96E7 -1.8 -2.2751 -0.993 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P03 compound treatment 5.69033567E8 2310000.0 0.04 5.6630448E8 6070000.0 0.14 0.1225 0.8634 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P04 compound treatment 5.16494055E8 -5.02E7 -0.78 4.71796469E8 -8.84E7 -2.0 -1.9665 -0.9162 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P05 compound treatment 5.82200543E8 1.55E7 0.24 5.48260142E8 -1.2E7 -0.27 -0.0209 -0.0576 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P06 compound treatment 4.62224954E8 -1.04E8 -1.63 4.43389148E8 -1.17E8 -2.64 -3.0182 -0.973 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P07 compound treatment 5.59896038E8 -6830000.0 -0.11 5.4637583E8 -1.39E7 -0.31 -0.2966 -0.8969 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P08 compound treatment 4.99799136E8 -6.69E7 -1.04 4.71323732E8 -8.89E7 -2.01 -2.1579 -0.9533 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P09 compound treatment 5.54516743E8 -1.22E7 -0.19 5.71240939E8 1.1E7 0.25 0.0415 0.1325 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P10 compound treatment 5.47365543E8 -1.94E7 -0.3 5.10893649E8 -4.93E7 -1.12 -1.0017 -0.8672 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P11 mock treatment 5.95105245E8 2.84E7 0.44 5.43314373E8 -1.69E7 -0.38 0.0422 0.0723 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P12 mock treatment 5.82833145E8 1.61E7 0.25 5.66565729E8 6330000.0 0.14 0.2786 0.9645 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P13 compound treatment 5.45321645E8 -2.14E7 -0.33 5.27675673E8 -3.26E7 -0.74 -0.756 -0.9359 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P14 compound treatment 5.31322264E8 -3.54E7 -0.55 5.04536143E8 -5.57E7 -1.26 -1.28 -0.9314 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P15 compound treatment 5.52676168E8 -1.4E7 -0.22 5.69527175E8 9290000.0 0.21 -0.0062 -0.0204 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P16 compound treatment 5.35284405E8 -3.14E7 -0.49 4.93789756E8 -6.64E7 -1.5 -1.4081 -0.8915 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P17 compound treatment 5.70919133E8 4200000.0 0.07 5.76624622E8 1.64E7 0.37 0.3082 0.8192 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P18 compound treatment 5.27641566E8 -3.91E7 -0.61 5.1825794E8 -4.2E7 -0.95 -1.1012 -0.977 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P19 compound treatment 5.60788795E8 -5930000.0 -0.09 5.5075356E8 -9480000.0 -0.21 -0.2168 -0.9294 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P20 compound treatment 4.7819629E8 -8.85E7 -1.38 4.22660261E8 -1.38E8 -3.11 -3.1735 -0.9331 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P21 compound treatment 5.64678907E8 -2040000.0 -0.03 5.54744114E8 -5490000.0 -0.12 -0.1102 -0.8606 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P22 compound treatment 2.08715003E8 -3.58E8 -5.58 1.7695532E8 -3.83E8 -8.66 -10.0681 -0.9773 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P23 compound treatment 5.69837273E8 3120000.0 0.05 5.33174106E8 -2.71E7 -0.61 -0.3981 -0.649 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2281 P24 compound treatment 1.62698195E8 -4.04E8 -6.29 3.7330894E8 -1.87E8 -4.22 -7.4371 -0.9812 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A01 compound treatment 6.42568233E8 5.56E7 0.87 6.30161632E8 5.22E7 1.18 1.4473 0.9885 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A02 compound treatment 6.79244017E8 9.23E7 1.44 6.52462859E8 7.45E7 1.68 2.2076 0.9969 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A03 compound treatment 6.42990913E8 5.61E7 0.87 6.18341013E8 4.04E7 0.91 1.263 0.9997 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A04 compound treatment 6.19128967E8 3.22E7 0.5 5.94954735E8 1.7E7 0.38 0.6265 0.9914 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A05 compound treatment 5.94818023E8 7880000.0 0.12 5.90096325E8 1.22E7 0.27 0.2811 0.934 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A06 compound treatment 5.96049782E8 9110000.0 0.14 5.90290638E8 1.24E7 0.28 0.2978 0.9508 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A07 compound treatment 5.88869259E8 1930000.0 0.03 5.81695561E8 3760000.0 0.08 0.0813 0.9026 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A08 compound treatment 6.08066391E8 2.11E7 0.33 5.9319348E8 1.53E7 0.34 0.4765 0.9997 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A09 compound treatment 6.18129101E8 3.12E7 0.49 5.88585367E8 1.06E7 0.24 0.5137 0.9475 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A10 compound treatment 5.95441138E8 8500000.0 0.13 5.6213605E8 -1.58E7 -0.36 -0.1589 -0.4171 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A11 compound treatment 5.85522253E8 -1420000.0 -0.02 5.61185084E8 -1.68E7 -0.38 -0.2833 -0.747 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A12 compound treatment 5.17535654E8 -6.94E7 -1.08 4.92285458E8 -8.57E7 -1.94 -2.1332 -0.9621 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A13 mock treatment 5.65129852E8 -2.18E7 -0.34 5.4591686E8 -3.2E7 -0.72 -0.7519 -0.9406 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A14 mock treatment 5.84816146E8 -2120000.0 -0.03 5.64095549E8 -1.38E7 -0.31 -0.2446 -0.7775 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A15 compound treatment 6.03019453E8 1.61E7 0.25 5.70734642E8 -7200000.0 -0.16 0.062 0.2076 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A16 compound treatment 5.42005836E8 -4.49E7 -0.7 5.54296097E8 -2.36E7 -0.53 -0.8727 -0.9911 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A17 compound treatment 5.68372449E8 -1.86E7 -0.29 5.47322096E8 -3.06E7 -0.69 -0.6937 -0.9251 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A18 compound treatment 5.61132222E8 -2.58E7 -0.4 5.50562798E8 -2.74E7 -0.62 -0.7217 -0.9782 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A19 compound treatment 5.58756562E8 -2.82E7 -0.44 5.39958211E8 -3.8E7 -0.86 -0.9173 -0.9515 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A20 compound treatment 5.66879296E8 -2.01E7 -0.31 5.46001641E8 -3.19E7 -0.72 -0.7313 -0.9298 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A21 compound treatment 5.6099157E8 -2.59E7 -0.4 5.53844039E8 -2.41E7 -0.54 -0.6708 -0.9892 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A22 compound treatment 5.70062974E8 -1.69E7 -0.26 5.61735882E8 -1.62E7 -0.37 -0.4448 -0.9868 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A23 compound treatment 5.78147787E8 -8790000.0 -0.14 5.40564496E8 -3.74E7 -0.84 -0.6941 -0.8111 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 A24 compound treatment 5.68376076E8 -1.86E7 -0.29 5.37844956E8 -4.01E7 -0.91 -0.8452 -0.8886 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B01 compound treatment 5.67433319E8 -1.95E7 -0.3 5.74545456E8 -3390000.0 -0.08 -0.269 -0.8586 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B02 compound treatment 5.27554543E8 -5.94E7 -0.92 5.55335506E8 -2.26E7 -0.51 -1.0152 -0.9608 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B03 compound treatment 5.76715709E8 -1.02E7 -0.16 5.6600529E8 -1.19E7 -0.27 -0.3033 -0.9684 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B04 compound treatment 5.88388878E8 1450000.0 0.02 5.93472014E8 1.55E7 0.35 0.2642 0.7511 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B05 compound treatment 5.81753443E8 -5180000.0 -0.08 5.76721917E8 -1220000.0 -0.03 -0.0765 -0.8972 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B06 compound treatment 6.04565589E8 1.76E7 0.27 5.54885128E8 -2.31E7 -0.52 -0.1743 -0.2959 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B07 compound treatment 5.73264843E8 -1.37E7 -0.21 5.53525007E8 -2.44E7 -0.55 -0.5407 -0.9143 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B08 compound treatment 5.79354649E8 -7580000.0 -0.12 5.85870232E8 7930000.0 0.18 0.0432 0.2014 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B09 compound treatment 5.78870032E8 -8070000.0 -0.13 5.45496388E8 -3.24E7 -0.73 -0.6073 -0.8164 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B10 compound treatment 5.79471646E8 -7470000.0 -0.12 5.51465811E8 -2.65E7 -0.6 -0.5053 -0.829 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B11 compound treatment 6.04902698E8 1.8E7 0.28 5.66356211E8 -1.16E7 -0.26 0.0128 0.0333 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B12 compound treatment 5.71503357E8 -1.54E7 -0.24 5.52079767E8 -2.59E7 -0.58 -0.5832 -0.923 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B13 mock treatment 5.70981034E8 -1.6E7 -0.25 5.57867747E8 -2.01E7 -0.45 -0.4965 -0.9599 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B14 mock treatment 5.79176136E8 -7760000.0 -0.12 5.54795694E8 -2.31E7 -0.52 -0.4553 -0.8482 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B15 compound treatment 5.85148511E8 -1790000.0 -0.03 5.6666522E8 -1.13E7 -0.25 -0.1999 -0.7798 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B16 compound treatment 5.55770543E8 -3.12E7 -0.49 5.48026456E8 -2.99E7 -0.68 -0.8213 -0.9868 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B17 compound treatment 5.87474757E8 536000.0 0.01 5.80261985E8 2320000.0 0.05 0.043 0.8094 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B18 compound treatment 5.59670343E8 -2.73E7 -0.42 5.62231256E8 -1.57E7 -0.35 -0.5513 -0.996 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B19 compound treatment 5.71180415E8 -1.58E7 -0.25 5.59274644E8 -1.87E7 -0.42 -0.4718 -0.9668 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B20 compound treatment 5.74482281E8 -1.25E7 -0.19 5.41319747E8 -3.66E7 -0.83 -0.7224 -0.8498 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B21 compound treatment 5.78103661E8 -8830000.0 -0.14 5.56792619E8 -2.11E7 -0.48 -0.4352 -0.8752 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B22 compound treatment 5.63564102E8 -2.34E7 -0.36 5.6144822E8 -1.65E7 -0.37 -0.521 -0.9999 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B23 compound treatment 5.79218811E8 -7720000.0 -0.12 5.5412226E8 -2.38E7 -0.54 -0.4656 -0.8443 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 B24 compound treatment 5.67501286E8 -1.94E7 -0.3 5.43136084E8 -3.48E7 -0.79 -0.7702 -0.9139 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C01 compound treatment 6.26689315E8 3.98E7 0.62 6.08754833E8 3.08E7 0.7 0.9303 0.9983 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C02 compound treatment 6.21896295E8 3.5E7 0.54 6.02018667E8 2.41E7 0.54 0.7698 1.0 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C03 compound treatment 6.1539831E8 2.85E7 0.44 6.0106582E8 2.31E7 0.52 0.6831 0.9966 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C04 compound treatment 4.78112322E8 -1.09E8 -1.7 4.71862914E8 -1.06E8 -2.4 -2.8937 -0.9856 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C05 compound treatment 6.23596288E8 3.67E7 0.57 5.66084891E8 -1.19E7 -0.27 0.2143 0.3398 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C06 compound treatment 6.38175625E8 5.12E7 0.8 5.70287258E8 -7650000.0 -0.17 0.4421 0.5413 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C07 compound treatment 6.58805019E8 7.19E7 1.12 6.50889329E8 7.3E7 1.65 1.9573 0.9822 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C08 compound treatment 6.52279488E8 6.53E7 1.02 6.0173108E8 2.38E7 0.54 1.0999 0.9555 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C09 compound treatment 6.3097804E8 4.4E7 0.69 6.06851136E8 2.89E7 0.65 0.9471 0.9997 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C10 compound treatment 6.27220534E8 4.03E7 0.63 6.1595924E8 3.8E7 0.86 1.0513 0.9881 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C11 mock treatment 6.22294169E8 3.54E7 0.55 5.91654689E8 1.37E7 0.31 0.6086 0.963 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C12 mock treatment 6.30661194E8 4.37E7 0.68 5.84621786E8 6680000.0 0.15 0.5884 0.8434 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C13 compound treatment 6.26032851E8 3.91E7 0.61 5.79523536E8 1590000.0 0.04 0.4559 0.7474 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C14 compound treatment 6.14058457E8 2.71E7 0.42 6.15037585E8 3.71E7 0.84 0.8916 0.9496 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C15 mock treatment 6.27125089E8 4.02E7 0.63 5.9760534E8 1.97E7 0.44 0.7569 0.9859 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C16 mock treatment 6.46856175E8 5.99E7 0.93 5.98789868E8 2.09E7 0.47 0.9932 0.9499 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C17 compound treatment 6.07977272E8 2.1E7 0.33 5.67572339E8 -1.04E7 -0.23 0.0661 0.164 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C18 compound treatment 6.17283206E8 3.03E7 0.47 5.75101111E8 -2840000.0 -0.06 0.2889 0.6056 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C19 compound treatment 5.99448167E8 1.25E7 0.19 5.8122878E8 3290000.0 0.07 0.1904 0.9128 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C20 compound treatment 6.28117691E8 4.12E7 0.64 5.81692773E8 3750000.0 0.08 0.5135 0.7937 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C21 compound treatment 5.93803743E8 6870000.0 0.11 5.62123241E8 -1.58E7 -0.36 -0.1771 -0.4748 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C22 compound treatment 6.13815299E8 2.69E7 0.42 5.65801626E8 -1.21E7 -0.27 0.1021 0.204 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C23 compound treatment 5.9809343E8 1.12E7 0.17 5.71266189E8 -6670000.0 -0.15 0.0162 0.0706 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 C24 compound treatment 5.77678806E8 -9260000.0 -0.14 5.594067E8 -1.85E7 -0.42 -0.3981 -0.8988 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D01 compound treatment 6.05617257E8 1.87E7 0.29 6.14116742E8 3.62E7 0.82 0.7839 0.9032 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D02 compound treatment 6.10928726E8 2.4E7 0.37 6.12813194E8 3.49E7 0.79 0.8216 0.9419 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D03 compound treatment 5.64870014E8 -2.21E7 -0.34 6.02421848E8 2.45E7 0.55 0.1482 0.2275 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D04 compound treatment 6.238025E8 3.69E7 0.57 6.11364179E8 3.34E7 0.76 0.9402 0.9908 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D05 compound treatment 6.45137561E8 5.82E7 0.91 6.49569732E8 7.16E7 1.62 1.7857 0.9624 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D06 compound treatment 5.81351911E8 -5590000.0 -0.09 6.20008401E8 4.21E7 0.95 0.6108 0.6397 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D07 compound treatment 6.15347888E8 2.84E7 0.44 6.06458579E8 2.85E7 0.64 0.7687 0.9832 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D08 compound treatment 6.00599547E8 1.37E7 0.21 5.99984952E8 2.2E7 0.5 0.5028 0.928 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D09 compound treatment 6.1070002E8 2.38E7 0.37 5.89171169E8 1.12E7 0.25 0.4412 0.9831 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D10 compound treatment 6.18825466E8 3.19E7 0.5 6.30050128E8 5.21E7 1.18 1.184 0.9263 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D11 mock treatment 6.03571451E8 1.66E7 0.26 5.94165611E8 1.62E7 0.37 0.4425 0.9855 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D12 mock treatment 6.31281365E8 4.43E7 0.69 6.16011629E8 3.81E7 0.86 1.0968 0.9941 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D13 compound treatment 6.23139941E8 3.62E7 0.56 5.86744224E8 8810000.0 0.2 0.5395 0.9021 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D14 compound treatment 6.03740132E8 1.68E7 0.26 6.13278994E8 3.53E7 0.8 0.7498 0.8921 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D15 mock treatment 6.26613136E8 3.97E7 0.62 6.09346458E8 3.14E7 0.71 0.9389 0.9976 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D16 mock treatment 6.11949297E8 2.5E7 0.39 5.96604378E8 1.87E7 0.42 0.5738 0.9992 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D17 compound treatment 5.93144485E8 6210000.0 0.1 5.7560105E8 -2340000.0 -0.05 0.031 0.2815 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D18 compound treatment 6.10598166E8 2.37E7 0.37 5.80623205E8 2690000.0 0.06 0.3035 0.8126 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D19 compound treatment 5.93468693E8 6530000.0 0.1 5.77331703E8 -606000.0 -0.01 0.0622 0.6064 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D20 compound treatment 6.25124686E8 3.82E7 0.59 5.84368992E8 6430000.0 0.15 0.5234 0.8547 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D21 compound treatment 5.74095442E8 -1.28E7 -0.2 5.89452714E8 1.15E7 0.26 0.0426 0.1297 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D22 compound treatment 6.02514899E8 1.56E7 0.24 5.95740773E8 1.78E7 0.4 0.4561 0.9707 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D23 compound treatment 5.96215771E8 9280000.0 0.14 5.70858315E8 -7080000.0 -0.16 -0.011 -0.0508 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 D24 compound treatment 5.91878811E8 4940000.0 0.08 5.53856039E8 -2.41E7 -0.54 -0.3304 -0.6011 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E01 mock treatment 5.6009687E8 -2.68E7 -0.42 5.59865185E8 -1.81E7 -0.41 -0.5844 -0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E02 mock treatment 5.70496106E8 -1.64E7 -0.26 5.37453196E8 -4.05E7 -0.91 -0.8281 -0.8715 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E03 compound treatment 5.73300322E8 -1.36E7 -0.21 5.36068061E8 -4.19E7 -0.95 -0.8193 -0.8448 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E04 compound treatment 5.41200759E8 -4.57E7 -0.71 5.19677269E8 -5.83E7 -1.32 -1.4348 -0.9584 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E05 compound treatment 5.4037973E8 -4.66E7 -0.73 5.44966918E8 -3.3E7 -0.75 -1.0397 -0.9999 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E06 compound treatment 5.28194116E8 -5.87E7 -0.91 5.50373634E8 -2.76E7 -0.62 -1.0875 -0.9824 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E07 compound treatment 5.71224609E8 -1.57E7 -0.24 5.70613838E8 -7320000.0 -0.17 -0.2901 -0.9819 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E08 compound treatment 5.61800408E8 -2.51E7 -0.39 5.57224789E8 -2.07E7 -0.47 -0.6079 -0.9961 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E09 mock treatment 5.56322508E8 -3.06E7 -0.48 5.53952023E8 -2.4E7 -0.54 -0.7205 -0.998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E10 mock treatment 5.45575109E8 -4.14E7 -0.64 5.56962377E8 -2.1E7 -0.47 -0.7908 -0.9886 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E11 compound treatment 5.48759711E8 -3.82E7 -0.59 5.60129169E8 -1.78E7 -0.4 -0.7051 -0.9819 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E12 compound treatment 5.13834483E8 -7.31E7 -1.14 5.64881622E8 -1.31E7 -0.3 -1.0138 -0.8619 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E13 compound treatment 5.50633254E8 -3.63E7 -0.57 5.32307069E8 -4.56E7 -1.03 -1.1291 -0.96 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E14 compound treatment 5.498658E8 -3.71E7 -0.58 5.40321439E8 -3.76E7 -0.85 -1.0094 -0.9822 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E15 compound treatment 5.50029098E8 -3.69E7 -0.57 5.73584415E8 -4350000.0 -0.1 -0.4761 -0.8163 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E16 compound treatment 5.44757167E8 -4.22E7 -0.66 5.75549489E8 -2390000.0 -0.05 -0.5027 -0.7626 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E17 mock treatment 5.53320335E8 -3.36E7 -0.52 5.67004381E8 -1.09E7 -0.25 -0.545 -0.9412 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E18 mock treatment 5.65412216E8 -2.15E7 -0.34 5.78544539E8 607000.0 0.01 -0.2274 -0.6776 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E19 compound treatment 5.20851354E8 -6.61E7 -1.03 5.53804946E8 -2.41E7 -0.55 -1.1135 -0.9559 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E20 compound treatment 5.35425463E8 -5.15E7 -0.8 5.52555058E8 -2.54E7 -0.57 -0.973 -0.9865 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E21 compound treatment 5.40523182E8 -4.64E7 -0.72 5.44758444E8 -3.32E7 -0.75 -1.0414 -0.9998 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E22 compound treatment 5.49503737E8 -3.74E7 -0.58 5.76000036E8 -1940000.0 -0.04 -0.4433 -0.7581 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E23 compound treatment 5.26336404E8 -6.06E7 -0.94 5.5603226E8 -2.19E7 -0.5 -1.0175 -0.9546 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 E24 compound treatment 5.21387898E8 -6.56E7 -1.02 5.48491348E8 -2.94E7 -0.67 -1.1925 -0.9785 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F01 mock treatment 5.81353265E8 -5590000.0 -0.09 5.73168934E8 -4770000.0 -0.11 -0.1377 -0.9944 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F02 mock treatment 5.91493505E8 4560000.0 0.07 5.53144948E8 -2.48E7 -0.56 -0.346 -0.6127 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F03 compound treatment 5.57733148E8 -2.92E7 -0.45 5.64895306E8 -1.3E7 -0.29 -0.5301 -0.9779 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F04 compound treatment 5.56595927E8 -3.03E7 -0.47 5.86524369E8 8590000.0 0.19 -0.197 -0.3855 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F05 compound treatment 5.94962185E8 8020000.0 0.12 5.61794103E8 -1.61E7 -0.36 -0.1696 -0.4398 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F06 compound treatment 5.61578777E8 -2.54E7 -0.4 5.84258246E8 6320000.0 0.14 -0.1783 -0.4245 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F07 compound treatment 5.6031398E8 -2.66E7 -0.41 5.79403705E8 1470000.0 0.03 -0.2698 -0.6486 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F08 compound treatment 5.45916317E8 -4.1E7 -0.64 5.72279826E8 -5660000.0 -0.13 -0.5422 -0.8321 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F09 mock treatment 5.37046919E8 -4.99E7 -0.78 5.65177205E8 -1.28E7 -0.29 -0.7534 -0.9089 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F10 mock treatment 5.68996619E8 -1.79E7 -0.28 5.68403211E8 -9530000.0 -0.22 -0.35 -0.9917 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F11 compound treatment 5.31536783E8 -5.54E7 -0.86 5.23150509E8 -5.48E7 -1.24 -1.4857 -0.9844 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F12 compound treatment 5.56239529E8 -3.07E7 -0.48 6.13755747E8 3.58E7 0.81 0.2343 0.2492 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F13 compound treatment 5.64317233E8 -2.26E7 -0.35 5.683095E8 -9630000.0 -0.22 -0.403 -0.9732 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F14 compound treatment 5.20423057E8 -6.65E7 -1.04 5.85283574E8 7350000.0 0.17 -0.6152 -0.5863 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F15 compound treatment 5.56177782E8 -3.08E7 -0.48 5.69303488E8 -8630000.0 -0.2 -0.4768 -0.9216 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F16 compound treatment 5.5292268E8 -3.4E7 -0.53 5.74730117E8 -3210000.0 -0.07 -0.4259 -0.7964 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F17 mock treatment 5.59903898E8 -2.7E7 -0.42 5.66285648E8 -1.17E7 -0.26 -0.484 -0.9745 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F18 mock treatment 5.5285813E8 -3.41E7 -0.53 5.69377086E8 -8560000.0 -0.19 -0.5122 -0.9065 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F19 compound treatment 5.26819057E8 -6.01E7 -0.94 5.52073354E8 -2.59E7 -0.58 -1.0755 -0.9743 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F20 compound treatment 5.96136875E8 9200000.0 0.14 6.11795445E8 3.39E7 0.77 0.6424 0.8252 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F21 compound treatment 5.60416514E8 -2.65E7 -0.41 5.59506578E8 -1.84E7 -0.42 -0.5867 -1.0 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F22 compound treatment 5.44353514E8 -4.26E7 -0.66 5.55407139E8 -2.25E7 -0.51 -0.8291 -0.9915 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F23 compound treatment 5.44090865E8 -4.28E7 -0.67 5.52647817E8 -2.53E7 -0.57 -0.8761 -0.997 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 F24 compound treatment 5.5366535E8 -3.33E7 -0.52 5.78541333E8 603000.0 0.01 -0.3568 -0.6883 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G01 compound treatment 6.02054271E8 1.51E7 0.24 5.72603023E8 -5330000.0 -0.12 0.0812 0.3071 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G02 compound treatment 5.73147836E8 -1.38E7 -0.21 5.76747236E8 -1190000.0 -0.03 -0.1709 -0.7895 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G03 mock treatment 5.80571914E8 -6370000.0 -0.1 5.88214934E8 1.03E7 0.23 0.0941 0.3727 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G04 mock treatment 5.8030717E8 -6630000.0 -0.1 6.23784769E8 4.58E7 1.04 0.6596 0.6335 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G05 compound treatment 5.81589846E8 -5350000.0 -0.08 5.99565689E8 2.16E7 0.49 0.2867 0.5783 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G06 compound treatment 5.93100781E8 6160000.0 0.1 6.02654255E8 2.47E7 0.56 0.4629 0.8166 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G07 compound treatment 6.08012899E8 2.11E7 0.33 6.12182102E8 3.42E7 0.77 0.7794 0.9271 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G08 compound treatment 6.28051076E8 4.11E7 0.64 6.1529307E8 3.74E7 0.84 1.0498 0.9907 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G09 compound treatment 6.1774249E8 3.08E7 0.48 5.86246529E8 8310000.0 0.19 0.4721 0.9162 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G10 compound treatment 5.80633561E8 -6300000.0 -0.1 6.04706124E8 2.68E7 0.6 0.3583 0.5847 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G11 compound treatment 5.86334631E8 -604000.0 -0.01 5.85665791E8 7730000.0 0.17 0.1168 0.6681 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G12 compound treatment 6.02183337E8 1.52E7 0.24 5.94101736E8 1.62E7 0.37 0.4262 0.9782 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G13 compound treatment 5.8430792E8 -2630000.0 -0.04 5.34905626E8 -4.3E7 -0.97 -0.7167 -0.7362 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G14 compound treatment 6.03620087E8 1.67E7 0.26 6.08938509E8 3.1E7 0.7 0.6791 0.9089 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G15 compound treatment 5.89060605E8 2120000.0 0.03 5.69425771E8 -8510000.0 -0.19 -0.1127 -0.5771 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G16 compound treatment 5.99149962E8 1.22E7 0.19 6.05832457E8 2.79E7 0.63 0.5803 0.8812 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G17 compound treatment 6.18262839E8 3.13E7 0.49 6.1741854E8 3.95E7 0.89 0.9759 0.9597 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G18 compound treatment 6.08120412E8 2.12E7 0.33 6.03606444E8 2.57E7 0.58 0.6435 0.9642 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G19 mock treatment 6.0403317E8 1.71E7 0.27 5.76897716E8 -1040000.0 -0.02 0.1717 0.6422 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G20 mock treatment 6.17647756E8 3.07E7 0.48 5.83651482E8 5710000.0 0.13 0.4295 0.867 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G21 compound treatment 5.76365885E8 -1.06E7 -0.16 5.78862172E8 924000.0 0.02 -0.1017 -0.6125 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G22 compound treatment 5.9066149E8 3720000.0 0.06 5.81836889E8 3900000.0 0.09 0.1033 0.9794 3071255 BCB03_000457 NC(=N)NCC#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G23 compound treatment 5.76780268E8 -1.02E7 -0.16 5.77968294E8 30400.0 0.0 -0.1114 -0.704 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 G24 compound treatment 6.00389233E8 1.35E7 0.21 5.7014368E8 -7790000.0 -0.18 0.0236 0.0862 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H01 compound treatment 6.40461978E8 5.35E7 0.83 5.95986604E8 1.8E7 0.41 0.8779 0.9459 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H02 compound treatment 5.94386389E8 7450000.0 0.12 6.31255706E8 5.33E7 1.2 0.9341 0.7716 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H03 mock treatment 6.374455E8 5.05E7 0.79 6.33125554E8 5.52E7 1.25 1.4382 0.9753 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H04 mock treatment 6.65328056E8 7.84E7 1.22 6.55067912E8 7.71E7 1.74 2.096 0.9848 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H05 compound treatment 6.52590403E8 6.57E7 1.02 6.45122008E8 6.72E7 1.52 1.7967 0.9815 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H06 compound treatment 6.29808867E8 4.29E7 0.67 6.29001154E8 5.11E7 1.15 1.2882 0.9662 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H07 compound treatment 6.09808491E8 2.29E7 0.36 6.4961956E8 7.17E7 1.62 1.3974 0.8425 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H08 compound treatment 5.96444999E8 9510000.0 0.15 6.02254975E8 2.43E7 0.55 0.4933 0.8667 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H09 compound treatment 5.93465506E8 6530000.0 0.1 5.42826721E8 -3.51E7 -0.79 -0.4892 -0.6115 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H10 compound treatment 6.23680607E8 3.67E7 0.57 6.00709387E8 2.28E7 0.51 0.7686 0.9986 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H11 compound treatment 6.24277074E8 3.73E7 0.58 5.86540732E8 8600000.0 0.19 0.5487 0.8948 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H12 compound treatment 6.16374809E8 2.94E7 0.46 6.08920753E8 3.1E7 0.7 0.8193 0.9789 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H13 compound treatment 6.30418866E8 4.35E7 0.68 6.13322136E8 3.54E7 0.8 1.0444 0.9966 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H14 compound treatment 6.12995028E8 2.61E7 0.41 5.90387791E8 1.24E7 0.28 0.4859 0.984 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H15 compound treatment 6.06612302E8 1.97E7 0.31 6.12835449E8 3.49E7 0.79 0.7744 0.9152 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H16 compound treatment 5.94614682E8 7680000.0 0.12 5.81310542E8 3370000.0 0.08 0.1384 0.9764 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H17 compound treatment 6.04253505E8 1.73E7 0.27 5.94274876E8 1.63E7 0.37 0.4518 0.9881 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H18 compound treatment 6.03605028E8 1.67E7 0.26 5.97859652E8 1.99E7 0.45 0.5019 0.9658 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H19 mock treatment 6.19193449E8 3.23E7 0.5 6.12440358E8 3.45E7 0.78 0.9066 0.9774 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H20 mock treatment 6.16512641E8 2.96E7 0.46 6.01172662E8 2.32E7 0.53 0.697 0.9979 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H21 compound treatment 6.22648509E8 3.57E7 0.56 6.00575317E8 2.26E7 0.51 0.7551 0.9991 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H22 compound treatment 3.67954297E8 -2.19E8 -3.41 5.16010445E8 -6.19E7 -1.4 -3.4015 -0.9226 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H23 compound treatment 5.84615372E8 -2320000.0 -0.04 5.90258481E8 1.23E7 0.28 0.1713 0.6101 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 H24 compound treatment 5.03798179E8 -8.31E7 -1.29 5.30786493E8 -4.72E7 -1.07 -1.6692 -0.9953 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I01 compound treatment 5.78910602E8 -8030000.0 -0.13 5.62111351E8 -1.58E7 -0.36 -0.3413 -0.9008 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I02 compound treatment 5.70721864E8 -1.62E7 -0.25 5.61480591E8 -1.65E7 -0.37 -0.4416 -0.9822 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I03 compound treatment 6.00288189E8 1.33E7 0.21 5.33650144E8 -4.43E7 -1.0 -0.5607 -0.5485 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I04 compound treatment 5.88322951E8 1380000.0 0.02 5.79541566E8 1600000.0 0.04 0.0409 0.9693 1035256 BCB03_000483 C#CCNCc1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I05 mock treatment 5.62061206E8 -2.49E7 -0.39 5.78785798E8 848000.0 0.02 -0.2604 -0.6713 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I06 mock treatment 5.574945E8 -2.94E7 -0.46 5.53505421E8 -2.44E7 -0.55 -0.7147 -0.9957 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I07 compound treatment 6.08129225E8 2.12E7 0.33 5.84290672E8 6350000.0 0.14 0.3349 0.9305 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I08 compound treatment 5.7252857E8 -1.44E7 -0.22 5.69233301E8 -8700000.0 -0.2 -0.2978 -0.9978 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I09 compound treatment 5.64806355E8 -2.21E7 -0.34 5.7501635E8 -2920000.0 -0.07 -0.2904 -0.8275 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I10 compound treatment 5.71951201E8 -1.5E7 -0.23 5.63464394E8 -1.45E7 -0.33 -0.3964 -0.9863 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I11 compound treatment 5.62869069E8 -2.41E7 -0.37 5.76402375E8 -1540000.0 -0.03 -0.2896 -0.7693 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I12 compound treatment 5.73568741E8 -1.34E7 -0.21 5.44792391E8 -3.31E7 -0.75 -0.6769 -0.8707 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I13 compound treatment 5.79000146E8 -7940000.0 -0.12 5.80218818E8 2280000.0 0.05 -0.051 -0.3806 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I14 compound treatment 5.86908075E8 -30300.0 0.0 5.77028744E8 -909000.0 -0.02 -0.0149 -0.7231 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I15 compound treatment 5.86871062E8 -67300.0 0.0 5.62568938E8 -1.54E7 -0.35 -0.2463 -0.7092 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I16 compound treatment 5.56179731E8 -3.08E7 -0.48 5.59159084E8 -1.88E7 -0.42 -0.6389 -0.9982 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I17 compound treatment 5.74250492E8 -1.27E7 -0.2 5.56515791E8 -2.14E7 -0.48 -0.4821 -0.9219 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I18 compound treatment 5.6716325E8 -1.98E7 -0.31 5.70966413E8 -6970000.0 -0.16 -0.3292 -0.9515 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I19 compound treatment 5.82275315E8 -4660000.0 -0.07 5.7222705E8 -5710000.0 -0.13 -0.1426 -0.963 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I20 compound treatment 5.51290657E8 -3.56E7 -0.56 5.47039724E8 -3.09E7 -0.7 -0.8864 -0.9936 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I21 mock treatment 5.74530149E8 -1.24E7 -0.19 5.62561823E8 -1.54E7 -0.35 -0.3824 -0.9617 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I22 mock treatment 5.54461402E8 -3.25E7 -0.51 5.61240686E8 -1.67E7 -0.38 -0.6245 -0.9896 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I23 compound treatment 5.67643054E8 -1.93E7 -0.3 5.45288551E8 -3.26E7 -0.74 -0.7343 -0.9216 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 I24 compound treatment 5.47399996E8 -3.95E7 -0.62 5.47796614E8 -3.01E7 -0.68 -0.9171 -0.9987 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J01 compound treatment 5.41443207E8 -4.55E7 -0.71 5.62063465E8 -1.59E7 -0.36 -0.7548 -0.9503 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J02 compound treatment 5.96226031E8 9290000.0 0.14 5.52759193E8 -2.52E7 -0.57 -0.3001 -0.5111 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J03 compound treatment 5.58284762E8 -2.87E7 -0.45 5.84804596E8 6870000.0 0.16 -0.2059 -0.4357 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J04 compound treatment 5.52119802E8 -3.48E7 -0.54 5.70198575E8 -7740000.0 -0.17 -0.5072 -0.89 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J05 mock treatment 5.93515011E8 6580000.0 0.1 5.9622041E8 1.83E7 0.41 0.3646 0.8565 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J06 mock treatment 5.78971297E8 -7970000.0 -0.12 5.79845063E8 1910000.0 0.04 -0.0573 -0.436 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J07 compound treatment 5.445466E8 -4.24E7 -0.66 5.88779481E8 1.08E7 0.25 -0.2936 -0.4169 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J08 compound treatment 5.23289307E8 -6.36E7 -0.99 5.26469679E8 -5.15E7 -1.16 -1.5235 -0.9968 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J09 compound treatment 5.39095578E8 -4.78E7 -0.75 5.9063224E8 1.27E7 0.29 -0.3241 -0.4058 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J10 compound treatment 5.20723698E8 -6.62E7 -1.03 5.35800282E8 -4.21E7 -0.95 -1.4027 -0.9992 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J11 compound treatment 5.28975138E8 -5.8E7 -0.9 5.82695071E8 4760000.0 0.11 -0.5624 -0.6185 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J12 compound treatment 5.15011869E8 -7.19E7 -1.12 5.62326826E8 -1.56E7 -0.35 -1.0417 -0.8869 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J13 compound treatment 5.44978141E8 -4.2E7 -0.65 5.27466192E8 -5.05E7 -1.14 -1.2687 -0.9651 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J14 compound treatment 5.07315544E8 -7.96E7 -1.24 5.6574492E8 -1.22E7 -0.28 -1.0718 -0.8436 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J15 compound treatment 4.9004078E8 -9.69E7 -1.51 5.26117906E8 -5.18E7 -1.17 -1.8953 -0.9921 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J16 compound treatment 5.2765756E8 -5.93E7 -0.92 5.55771249E8 -2.22E7 -0.5 -1.0071 -0.9587 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J17 compound treatment 5.32532158E8 -5.44E7 -0.85 5.45423978E8 -3.25E7 -0.73 -1.1188 -0.9975 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J18 compound treatment 5.51509006E8 -3.54E7 -0.55 5.71025073E8 -6910000.0 -0.16 -0.5007 -0.873 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J19 compound treatment 5.45660201E8 -4.13E7 -0.64 5.45120319E8 -3.28E7 -0.74 -0.9791 -0.9975 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J20 compound treatment 5.41349039E8 -4.56E7 -0.71 5.24188383E8 -5.37E7 -1.21 -1.3611 -0.9673 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J21 mock treatment 5.64466231E8 -2.25E7 -0.35 5.83246111E8 5310000.0 0.12 -0.1627 -0.4397 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J22 mock treatment 5.62856475E8 -2.41E7 -0.38 5.60877103E8 -1.71E7 -0.39 -0.5379 -0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J23 compound treatment 5.39735733E8 -4.72E7 -0.74 5.48928798E8 -2.9E7 -0.66 -0.9835 -0.9984 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 J24 compound treatment 5.36228633E8 -5.07E7 -0.79 5.24603405E8 -5.33E7 -1.21 -1.4108 -0.979 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K01 compound treatment 5.56669021E8 -3.03E7 -0.47 5.82698071E8 4760000.0 0.11 -0.2573 -0.5321 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K02 compound treatment 5.79051131E8 -7890000.0 -0.12 5.52016279E8 -2.59E7 -0.59 -0.5011 -0.8372 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K03 compound treatment 5.77903398E8 -9030000.0 -0.14 5.97425132E8 1.95E7 0.44 0.2119 0.4583 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K04 compound treatment 5.70406898E8 -1.65E7 -0.26 5.59561738E8 -1.84E7 -0.42 -0.4757 -0.9736 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K05 compound treatment 5.75893243E8 -1.1E7 -0.17 5.6618667E8 -1.18E7 -0.27 -0.3094 -0.9779 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K06 compound treatment 5.72664481E8 -1.43E7 -0.22 5.65238848E8 -1.27E7 -0.29 -0.3602 -0.992 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K07 mock treatment 6.04842701E8 1.79E7 0.28 5.99443501E8 2.15E7 0.49 0.5409 0.9652 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K08 mock treatment 5.90342789E8 3400000.0 0.05 5.85692794E8 7750000.0 0.18 0.1614 0.8816 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K09 compound treatment 5.9814664E8 1.12E7 0.17 5.8776075E8 9820000.0 0.22 0.2804 0.9929 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K10 compound treatment 5.79795379E8 -7140000.0 -0.11 5.72846887E8 -5090000.0 -0.12 -0.16 -0.9999 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K11 compound treatment 5.86583181E8 -355000.0 -0.01 5.78094537E8 157000.0 0.0 -0.0014 -0.2145 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K12 compound treatment 6.22253138E8 3.53E7 0.55 5.76967643E8 -970000.0 -0.02 0.3734 0.6784 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K13 compound treatment 5.75267301E8 -1.17E7 -0.18 5.38955068E8 -3.9E7 -0.88 -0.7515 -0.8354 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K14 compound treatment 5.73868557E8 -1.31E7 -0.2 5.55308064E8 -2.26E7 -0.51 -0.5056 -0.9185 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K15 mock treatment 5.96952117E8 1.0E7 0.16 5.52236167E8 -2.57E7 -0.58 -0.3004 -0.4995 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K16 mock treatment 6.00952167E8 1.4E7 0.22 5.42694673E8 -3.52E7 -0.8 -0.4089 -0.4951 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K17 compound treatment 5.94845822E8 7910000.0 0.12 5.68894525E8 -9040000.0 -0.2 -0.0574 -0.2407 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K18 compound treatment 5.76739724E8 -1.02E7 -0.16 5.58835582E8 -1.91E7 -0.43 -0.4176 -0.9078 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K19 compound treatment 5.83419965E8 -3520000.0 -0.05 5.59305542E8 -1.86E7 -0.42 -0.3365 -0.7924 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K20 compound treatment 5.85160224E8 -1780000.0 -0.03 5.33205233E8 -4.47E7 -1.01 -0.7344 -0.7262 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K21 compound treatment 5.84835693E8 -2100000.0 -0.03 5.42016564E8 -3.59E7 -0.81 -0.5972 -0.735 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K22 compound treatment 5.79329872E8 -7610000.0 -0.12 5.50243407E8 -2.77E7 -0.63 -0.5264 -0.8263 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K23 mock treatment 5.7522297E8 -1.17E7 -0.18 5.60349969E8 -1.76E7 -0.4 -0.4101 -0.9376 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 K24 mock treatment 5.70526434E8 -1.64E7 -0.26 5.3925317E8 -3.87E7 -0.87 -0.799 -0.8771 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L01 compound treatment 5.51640824E8 -3.53E7 -0.55 5.33218216E8 -4.47E7 -1.01 -1.1034 -0.959 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L02 compound treatment 6.2267508E8 3.57E7 0.56 5.82136485E8 4200000.0 0.09 0.4607 0.8159 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L03 compound treatment 5.92929543E8 5990000.0 0.09 5.88072947E8 1.01E7 0.23 0.228 0.9216 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L04 compound treatment 5.99742662E8 1.28E7 0.2 5.79045787E8 1110000.0 0.03 0.1587 0.7897 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L05 compound treatment 6.3386241E8 4.69E7 0.73 6.12930316E8 3.5E7 0.79 1.076 0.9992 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L06 compound treatment 6.41933092E8 5.5E7 0.86 5.6922787E8 -8710000.0 -0.2 0.4665 0.5308 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L07 mock treatment 5.7491411E8 -1.2E7 -0.19 6.26713175E8 4.88E7 1.1 0.647 0.5787 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L08 mock treatment 6.08650525E8 2.17E7 0.34 5.79704064E8 1770000.0 0.04 0.2674 0.7851 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L09 compound treatment 5.77892291E8 -9050000.0 -0.14 5.57829485E8 -2.01E7 -0.45 -0.421 -0.8848 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L10 compound treatment 5.93108602E8 6170000.0 0.1 5.70343165E8 -7590000.0 -0.17 -0.0534 -0.2715 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L11 compound treatment 5.84818283E8 -2120000.0 -0.03 5.73715308E8 -4220000.0 -0.1 -0.0908 -0.8995 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L12 compound treatment 5.95041272E8 8100000.0 0.13 5.83251094E8 5310000.0 0.12 0.1742 0.9997 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L13 compound treatment 5.70553574E8 -1.64E7 -0.26 5.16164977E8 -6.18E7 -1.4 -1.1676 -0.8227 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L14 compound treatment 5.56712723E8 -3.02E7 -0.47 5.19832158E8 -5.81E7 -1.31 -1.2615 -0.9043 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L15 mock treatment 5.79492671E8 -7450000.0 -0.12 5.63482998E8 -1.45E7 -0.33 -0.313 -0.9029 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L16 mock treatment 6.04701128E8 1.78E7 0.28 5.67691542E8 -1.02E7 -0.23 0.0319 0.0884 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L17 compound treatment 5.83809125E8 -3130000.0 -0.05 5.77412232E8 -526000.0 -0.01 -0.0429 -0.8544 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L18 compound treatment 5.83967841E8 -2970000.0 -0.05 5.29111964E8 -4.88E7 -1.1 -0.813 -0.7361 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L19 compound treatment 5.88320282E8 1380000.0 0.02 5.75178098E8 -2760000.0 -0.06 -0.0289 -0.4377 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L20 compound treatment 5.64653776E8 -2.23E7 -0.35 5.42582327E8 -3.54E7 -0.8 -0.8104 -0.9303 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L21 compound treatment 5.72212154E8 -1.47E7 -0.23 5.32796652E8 -4.51E7 -1.02 -0.8836 -0.845 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L22 compound treatment 4.77669718E8 -1.09E8 -1.7 4.49424508E8 -1.29E8 -2.9 -3.2572 -0.9676 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L23 mock treatment 5.90290392E8 3350000.0 0.05 5.60084664E8 -1.79E7 -0.4 -0.2484 -0.6105 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 L24 mock treatment 5.87304847E8 367000.0 0.01 5.59460071E8 -1.85E7 -0.42 -0.2913 -0.6974 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M01 compound treatment 5.74141867E8 -1.28E7 -0.2 5.43974852E8 -3.4E7 -0.77 -0.6837 -0.8621 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M02 compound treatment 5.48774872E8 -3.82E7 -0.59 5.5966537E8 -1.83E7 -0.41 -0.7123 -0.9842 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M03 compound treatment 5.62698918E8 -2.42E7 -0.38 5.85464841E8 7530000.0 0.17 -0.1467 -0.3542 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M04 compound treatment 5.25616337E8 -6.13E7 -0.96 5.48054285E8 -2.99E7 -0.68 -1.153 -0.9856 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M05 compound treatment 5.83813322E8 -3130000.0 -0.05 6.13853123E8 3.59E7 0.81 0.5395 0.6635 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M06 compound treatment 5.63270453E8 -2.37E7 -0.37 5.67731219E8 -1.02E7 -0.23 -0.4238 -0.9745 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M07 compound treatment 5.77478504E8 -9460000.0 -0.15 5.92053788E8 1.41E7 0.32 0.1214 0.3454 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M08 compound treatment 5.5969189E8 -2.72E7 -0.42 5.40681902E8 -3.73E7 -0.84 -0.8955 -0.9497 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M09 mock treatment 5.76718765E8 -1.02E7 -0.16 5.4436653E8 -3.36E7 -0.76 -0.649 -0.8372 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M10 mock treatment 5.91417743E8 4480000.0 0.07 5.66071642E8 -1.19E7 -0.27 -0.1403 -0.5063 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M11 compound treatment 5.70222208E8 -1.67E7 -0.26 5.7516557E8 -2770000.0 -0.06 -0.2284 -0.8529 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M12 compound treatment 5.82835539E8 -4100000.0 -0.06 5.20727797E8 -5.72E7 -1.29 -0.9594 -0.7412 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M13 mock treatment 5.66441104E8 -2.05E7 -0.32 5.80836931E8 2900000.0 0.07 -0.1794 -0.5505 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M14 mock treatment 5.65914297E8 -2.1E7 -0.33 5.58650062E8 -1.93E7 -0.44 -0.5398 -0.9901 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M15 compound treatment 5.6931208E8 -1.76E7 -0.27 5.42747659E8 -3.52E7 -0.8 -0.7565 -0.8991 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M16 compound treatment 4.9028512E8 -9.67E7 -1.51 5.07576356E8 -7.04E7 -1.59 -2.189 -0.9996 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M17 compound treatment 5.63269732E8 -2.37E7 -0.37 5.74328806E8 -3610000.0 -0.08 -0.3184 -0.8432 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M18 compound treatment 5.60288829E8 -2.66E7 -0.42 5.63825107E8 -1.41E7 -0.32 -0.519 -0.9915 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M19 compound treatment 5.70096877E8 -1.68E7 -0.26 5.69196421E8 -8740000.0 -0.2 -0.3252 -0.9902 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M20 compound treatment 5.50319415E8 -3.66E7 -0.57 5.3339481E8 -4.45E7 -1.01 -1.1151 -0.9638 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M21 compound treatment 5.73508117E8 -1.34E7 -0.21 5.54910607E8 -2.3E7 -0.52 -0.5159 -0.9198 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M22 compound treatment 5.36370722E8 -5.06E7 -0.79 5.47839974E8 -3.01E7 -0.68 -1.0379 -0.9973 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M23 compound treatment 5.31153412E8 -5.58E7 -0.87 5.45146119E8 -3.28E7 -0.74 -1.1384 -0.9969 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 M24 compound treatment 5.2728112E8 -5.97E7 -0.93 5.32867956E8 -4.51E7 -1.02 -1.3773 -0.9989 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N01 compound treatment 5.64912111E8 -2.2E7 -0.34 5.80842005E8 2900000.0 0.07 -0.1962 -0.5616 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N02 compound treatment 6.08655655E8 2.17E7 0.34 6.3310857E8 5.52E7 1.25 1.1209 0.8676 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N03 compound treatment 6.14901906E8 2.8E7 0.44 6.39923302E8 6.2E7 1.4 1.2986 0.8852 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N04 compound treatment 5.58866673E8 -2.81E7 -0.44 5.68150799E8 -9790000.0 -0.22 -0.4656 -0.9502 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N05 compound treatment 6.03352253E8 1.64E7 0.26 6.39796996E8 6.19E7 1.4 1.1693 0.8228 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N06 compound treatment 4.90057896E8 -9.69E7 -1.51 5.18462787E8 -5.95E7 -1.34 -2.0175 -0.9983 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N07 compound treatment 5.77607313E8 -9330000.0 -0.15 5.87688835E8 9750000.0 0.22 0.0531 0.201 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N08 compound treatment 5.87881728E8 943000.0 0.01 5.78962661E8 1020000.0 0.02 0.0268 0.9759 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N09 mock treatment 5.77636298E8 -9300000.0 -0.14 6.1006409E8 3.21E7 0.73 0.4109 0.5551 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N10 mock treatment 5.78380614E8 -8560000.0 -0.13 5.82829971E8 4890000.0 0.11 -0.0161 -0.0928 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N11 compound treatment 6.09995031E8 2.31E7 0.36 5.87248662E8 9310000.0 0.21 0.4027 0.9676 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N12 compound treatment 5.26745963E8 -6.02E7 -0.94 5.50570273E8 -2.74E7 -0.62 -1.1003 -0.9796 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N13 mock treatment 5.95321939E8 8380000.0 0.13 6.007767E8 2.28E7 0.52 0.4573 0.8589 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N14 mock treatment 5.85853712E8 -1080000.0 -0.02 5.98751072E8 2.08E7 0.47 0.3207 0.6813 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N15 compound treatment 5.61768167E8 -2.52E7 -0.39 5.84935571E8 7000000.0 0.16 -0.1654 -0.3912 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N16 compound treatment 5.33088918E8 -5.38E7 -0.84 5.02781821E8 -7.52E7 -1.7 -1.7941 -0.9471 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N17 compound treatment 5.68750385E8 -1.82E7 -0.28 5.96240558E8 1.83E7 0.41 0.0922 0.1838 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N18 compound treatment 5.13379568E8 -7.36E7 -1.15 5.4101536E8 -3.69E7 -0.83 -1.4002 -0.9879 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N19 compound treatment 5.68110038E8 -1.88E7 -0.29 5.6662269E8 -1.13E7 -0.26 -0.3882 -0.9977 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N20 compound treatment 5.07763188E8 -7.92E7 -1.23 5.22386763E8 -5.56E7 -1.26 -1.7598 -1.0 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N21 compound treatment 5.75228693E8 -1.17E7 -0.18 5.75319281E8 -2620000.0 -0.06 -0.1708 -0.8908 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N22 compound treatment 5.08188689E8 -7.87E7 -1.23 5.34861528E8 -4.31E7 -0.97 -1.5557 -0.9934 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N23 compound treatment 5.65035174E8 -2.19E7 -0.34 5.66075865E8 -1.19E7 -0.27 -0.4308 -0.9929 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 N24 compound treatment 5.38662818E8 -4.83E7 -0.75 5.31761597E8 -4.62E7 -1.04 -1.2696 -0.9871 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O01 compound treatment 5.66306158E8 -2.06E7 -0.32 5.46686146E8 -3.13E7 -0.71 -0.7267 -0.9365 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O02 compound treatment 5.41580949E8 -4.54E7 -0.71 5.517544E8 -2.62E7 -0.59 -0.918 -0.9961 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O03 compound treatment 5.85257418E8 -1680000.0 -0.03 5.6525216E8 -1.27E7 -0.29 -0.2212 -0.7685 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O04 compound treatment 5.70930007E8 -1.6E7 -0.25 5.77827111E8 -111000.0 0.0 -0.1781 -0.7142 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O05 compound treatment 5.83141108E8 -3800000.0 -0.06 5.83689471E8 5750000.0 0.13 0.0501 0.3508 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O06 compound treatment 5.79910712E8 -7030000.0 -0.11 5.80282702E8 2340000.0 0.05 -0.0399 -0.3283 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O07 compound treatment 5.93835536E8 6900000.0 0.11 5.68814319E8 -9120000.0 -0.21 -0.0698 -0.3004 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O08 compound treatment 5.31859881E8 -5.51E7 -0.86 5.43947783E8 -3.4E7 -0.77 -1.1498 -0.9985 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O09 compound treatment 5.68036563E8 -1.89E7 -0.29 5.83501396E8 5560000.0 0.13 -0.1193 -0.3726 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O10 compound treatment 5.76828495E8 -1.01E7 -0.16 5.77779751E8 -158000.0 0.0 -0.1139 -0.723 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O11 mock treatment 5.822247E8 -4710000.0 -0.07 6.05492391E8 2.76E7 0.62 0.3884 0.6194 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O12 mock treatment 5.89203148E8 2260000.0 0.04 5.99230891E8 2.13E7 0.48 0.3652 0.7569 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O13 compound treatment 5.68329697E8 -1.86E7 -0.29 5.4116436E8 -3.68E7 -0.83 -0.7926 -0.9005 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O14 compound treatment 5.62108953E8 -2.48E7 -0.39 5.69706039E8 -8230000.0 -0.19 -0.405 -0.9437 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O15 compound treatment 5.78041434E8 -8900000.0 -0.14 5.44086733E8 -3.39E7 -0.77 -0.639 -0.8218 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O16 compound treatment 5.77051332E8 -9890000.0 -0.15 5.55521361E8 -2.24E7 -0.51 -0.4671 -0.8822 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O17 compound treatment 5.70361029E8 -1.66E7 -0.26 5.715083E8 -6430000.0 -0.15 -0.2853 -0.963 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O18 compound treatment 5.690556E8 -1.79E7 -0.28 5.66001571E8 -1.19E7 -0.27 -0.3877 -0.9999 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O19 compound treatment 5.48303889E8 -3.86E7 -0.6 5.43381761E8 -3.46E7 -0.78 -0.9777 -0.9917 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O20 compound treatment 5.61316625E8 -2.56E7 -0.4 5.45641029E8 -3.23E7 -0.73 -0.7983 -0.9596 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O21 compound treatment 5.64372704E8 -2.26E7 -0.35 5.39664698E8 -3.83E7 -0.86 -0.8602 -0.9213 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O22 compound treatment 5.71473301E8 -1.55E7 -0.24 5.59846136E8 -1.81E7 -0.41 -0.4594 -0.9682 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O23 compound treatment 5.67096845E8 -1.98E7 -0.31 5.5383514E8 -2.41E7 -0.54 -0.6037 -0.9639 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 O24 compound treatment 5.6085879E8 -2.61E7 -0.41 5.44406717E8 -3.35E7 -0.76 -0.8231 -0.9573 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P01 compound treatment 5.82218639E8 -4720000.0 -0.07 5.71124775E8 -6810000.0 -0.15 -0.1609 -0.9428 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P02 compound treatment 5.85215609E8 -1720000.0 -0.03 5.67486088E8 -1.05E7 -0.24 -0.186 -0.7824 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P03 compound treatment 5.70925789E8 -1.6E7 -0.25 6.13768011E8 3.58E7 0.81 0.3962 0.4676 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P04 compound treatment 5.79437449E8 -7500000.0 -0.12 6.12076864E8 3.41E7 0.77 0.4629 0.5933 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P05 compound treatment 5.9318538E8 6250000.0 0.1 5.65992911E8 -1.19E7 -0.27 -0.1221 -0.4254 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P06 compound treatment 5.96299199E8 9360000.0 0.15 5.92375239E8 1.44E7 0.33 0.3338 0.9341 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P07 compound treatment 5.84829022E8 -2110000.0 -0.03 5.8513241E8 7190000.0 0.16 0.0917 0.553 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P08 compound treatment 5.86865564E8 -72800.0 0.0 5.98308138E8 2.04E7 0.46 0.3247 0.7054 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P09 compound treatment 5.91265308E8 4330000.0 0.07 5.84803982E8 6870000.0 0.16 0.1574 0.9303 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P10 compound treatment 5.92155355E8 5220000.0 0.08 5.60073595E8 -1.79E7 -0.4 -0.228 -0.5537 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P11 mock treatment 5.63621293E8 -2.33E7 -0.36 5.82230952E8 4290000.0 0.1 -0.1882 -0.5007 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P12 mock treatment 5.94400494E8 7460000.0 0.12 5.87596344E8 9660000.0 0.22 0.2365 0.9565 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P13 compound treatment 5.75591853E8 -1.13E7 -0.18 5.45133015E8 -3.28E7 -0.74 -0.6492 -0.8518 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P14 compound treatment 5.57439297E8 -2.95E7 -0.46 5.56010823E8 -2.19E7 -0.5 -0.6753 -0.9993 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P15 compound treatment 5.85072504E8 -1870000.0 -0.03 5.54991626E8 -2.29E7 -0.52 -0.3872 -0.7456 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P16 compound treatment 6.01204093E8 1.43E7 0.22 5.5856973E8 -1.94E7 -0.44 -0.1524 -0.3104 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P17 compound treatment 5.88995995E8 2060000.0 0.03 5.59209125E8 -1.87E7 -0.42 -0.2766 -0.6517 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P18 compound treatment 5.7986527E8 -7070000.0 -0.11 5.51410598E8 -2.65E7 -0.6 -0.5018 -0.8233 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P19 compound treatment 5.72200678E8 -1.47E7 -0.23 5.61258199E8 -1.67E7 -0.38 -0.4289 -0.9717 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P20 compound treatment 5.87010615E8 72300.0 0.0 5.54976812E8 -2.3E7 -0.52 -0.3661 -0.7056 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P21 compound treatment 5.74150086E8 -1.28E7 -0.2 5.42572541E8 -3.54E7 -0.8 -0.706 -0.8571 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P22 compound treatment 6.04612923E8 1.77E7 0.28 5.68808705E8 -9130000.0 -0.21 0.0488 0.1418 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P23 compound treatment 5.561075E8 -3.08E7 -0.48 5.41096884E8 -3.68E7 -0.83 -0.9283 -0.9658 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2282 P24 compound treatment 5.66882915E8 -2.01E7 -0.31 5.53513373E8 -2.44E7 -0.55 -0.6112 -0.9637 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A01 compound treatment 5.82552454E8 4.45E7 0.69 6.54708503E8 7.82E7 1.77 1.7391 0.9164 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A02 compound treatment 5.70725304E8 3.26E7 0.51 6.19619531E8 4.31E7 0.97 1.0481 0.954 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A03 compound treatment 5.68942791E8 3.09E7 0.48 5.99411248E8 2.29E7 0.52 0.7056 0.9993 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A04 compound treatment 5.84536752E8 4.64E7 0.72 6.04886781E8 2.84E7 0.64 0.9648 0.9982 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A05 compound treatment 5.87059369E8 4.9E7 0.76 5.91352183E8 1.48E7 0.34 0.7763 0.9318 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A06 compound treatment 5.56132464E8 1.8E7 0.28 5.85587784E8 9060000.0 0.2 0.3436 0.9879 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A07 compound treatment 5.46396718E8 8310000.0 0.13 5.5861817E8 -1.79E7 -0.4 -0.1947 -0.4582 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A08 compound treatment 5.62550544E8 2.45E7 0.38 5.75377709E8 -1150000.0 -0.03 0.2511 0.6575 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A09 compound treatment 5.4425924E8 6170000.0 0.1 5.17549388E8 -5.9E7 -1.33 -0.8745 -0.6544 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A10 compound treatment 5.46654662E8 8570000.0 0.13 5.50075037E8 -2.65E7 -0.6 -0.3284 -0.5361 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A11 compound treatment 5.18272102E8 -1.98E7 -0.31 5.48128793E8 -2.84E7 -0.64 -0.6721 -0.9437 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A12 compound treatment 5.22236724E8 -1.59E7 -0.25 5.31199471E8 -4.53E7 -1.02 -0.8989 -0.8531 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A13 mock treatment 5.41150373E8 3060000.0 0.05 5.49827591E8 -2.67E7 -0.6 -0.3929 -0.6492 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A14 mock treatment 5.04840321E8 -3.32E7 -0.52 5.57086835E8 -1.94E7 -0.44 -0.6768 -0.9966 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A15 compound treatment 4.71623404E8 -6.65E7 -1.04 5.60062712E8 -1.65E7 -0.37 -0.9951 -0.9046 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A16 compound treatment 4.79440423E8 -5.86E7 -0.91 5.27066211E8 -4.95E7 -1.12 -1.4363 -0.995 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A17 compound treatment 4.88224771E8 -4.99E7 -0.78 5.32615393E8 -4.39E7 -0.99 -1.2509 -0.9927 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A18 compound treatment 4.9985393E8 -3.82E7 -0.6 5.59215903E8 -1.73E7 -0.39 -0.6977 -0.9792 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A19 compound treatment 4.93730366E8 -4.44E7 -0.69 5.47064221E8 -2.95E7 -0.67 -0.9594 -0.9998 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A20 compound treatment 4.78304976E8 -5.98E7 -0.93 5.40985602E8 -3.55E7 -0.8 -1.2264 -0.9973 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A21 compound treatment 4.85866628E8 -5.22E7 -0.81 5.29983013E8 -4.65E7 -1.05 -1.3189 -0.9919 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A22 compound treatment 5.05809142E8 -3.23E7 -0.5 5.7092647E8 -5600000.0 -0.13 -0.445 -0.8583 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A23 compound treatment 5.10721015E8 -2.74E7 -0.43 5.44603011E8 -3.19E7 -0.72 -0.8116 -0.9685 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 A24 compound treatment 5.0925915E8 -2.88E7 -0.45 5.75615464E8 -910000.0 -0.02 -0.3321 -0.7387 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B01 compound treatment 5.27983557E8 -1.01E7 -0.16 5.58072674E8 -1.85E7 -0.42 -0.4062 -0.9113 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B02 compound treatment 5.4860205E8 1.05E7 0.16 5.58466061E8 -1.81E7 -0.41 -0.1728 -0.393 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B03 compound treatment 5.13319773E8 -2.48E7 -0.39 5.78905543E8 2380000.0 0.05 -0.2348 -0.6027 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B04 compound treatment 5.57308509E8 1.92E7 0.3 5.75003218E8 -1520000.0 -0.03 0.1874 0.6218 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B05 compound treatment 5.63294479E8 2.52E7 0.39 5.76128075E8 -397000.0 -0.01 0.2713 0.6908 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B06 compound treatment 5.21972349E8 -1.61E7 -0.25 5.4481976E8 -3.17E7 -0.72 -0.6842 -0.9011 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B07 compound treatment 5.6518523E8 2.71E7 0.42 5.55755705E8 -2.08E7 -0.47 -0.0335 -0.053 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B08 compound treatment 5.32916968E8 -5170000.0 -0.08 5.91095252E8 1.46E7 0.33 0.1759 0.5188 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B09 compound treatment 5.27821857E8 -1.03E7 -0.16 5.53158305E8 -2.34E7 -0.53 -0.4865 -0.8817 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B10 compound treatment 5.19041541E8 -1.9E7 -0.3 5.45157392E8 -3.14E7 -0.71 -0.7111 -0.9253 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B11 compound treatment 3.47975849E8 -1.9E8 -2.96 3.63576281E8 -2.13E8 -4.81 -5.4969 -0.9728 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B12 compound treatment 5.01202269E8 -3.69E7 -0.57 5.43604965E8 -3.29E7 -0.74 -0.9324 -0.9918 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B13 mock treatment 5.25746348E8 -1.23E7 -0.19 5.43191101E8 -3.33E7 -0.75 -0.6686 -0.86 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B14 mock treatment 5.11970141E8 -2.61E7 -0.41 5.58206395E8 -1.83E7 -0.41 -0.5804 -1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B15 compound treatment 2.92276098E8 -2.46E8 -3.83 2.6521457E8 -3.11E8 -7.04 -7.6823 -0.9591 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B16 compound treatment 5.56884491E8 1.88E7 0.29 5.65145526E8 -1.14E7 -0.26 0.0252 0.0646 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B17 compound treatment 4.92341741E8 -4.57E7 -0.71 5.05902461E8 -7.06E7 -1.6 -1.6325 -0.9339 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B18 compound treatment 5.3627485E8 -1810000.0 -0.03 5.61952476E8 -1.46E7 -0.33 -0.2529 -0.765 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B19 compound treatment 4.86755853E8 -5.13E7 -0.8 5.15540126E8 -6.1E7 -1.38 -1.54 -0.9665 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B20 compound treatment 5.32351247E8 -5740000.0 -0.09 5.6475297E8 -1.18E7 -0.27 -0.2513 -0.8955 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B21 compound treatment 5.34980397E8 -3110000.0 -0.05 5.35405571E8 -4.11E7 -0.93 -0.6914 -0.7429 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B22 compound treatment 5.23071524E8 -1.5E7 -0.23 5.6195179E8 -1.46E7 -0.33 -0.3983 -0.9859 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B23 compound treatment 4.84096902E8 -5.4E7 -0.84 5.07984074E8 -6.85E7 -1.55 -1.69 -0.9588 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 B24 compound treatment 5.1674216E8 -2.13E7 -0.33 5.60217119E8 -1.63E7 -0.37 -0.4957 -0.9987 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C01 compound treatment 5.76953684E8 3.89E7 0.61 6.47710404E8 7.12E7 1.61 1.5656 0.9108 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C02 compound treatment 5.48673497E8 1.06E7 0.16 5.97888096E8 2.14E7 0.48 0.458 0.8977 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C03 compound treatment 5.63061572E8 2.5E7 0.39 5.90867822E8 1.43E7 0.32 0.5042 0.9959 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C04 compound treatment 5.66967139E8 2.89E7 0.45 5.76998705E8 474000.0 0.01 0.3256 0.7237 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C05 compound treatment 5.89004924E8 5.09E7 0.79 5.87203687E8 1.07E7 0.24 0.7314 0.8823 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C06 compound treatment 5.82004412E8 4.39E7 0.68 6.26869138E8 5.03E7 1.14 1.2882 0.9704 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C07 compound treatment 5.46345498E8 8260000.0 0.13 5.92942377E8 1.64E7 0.37 0.3533 0.8997 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C08 compound treatment 5.87808534E8 4.97E7 0.77 6.17300704E8 4.08E7 0.92 1.1992 0.9963 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C09 compound treatment 5.94215372E8 5.61E7 0.87 5.66946563E8 -9580000.0 -0.22 0.4651 0.5164 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C10 compound treatment 5.63531796E8 2.54E7 0.4 5.54770445E8 -2.18E7 -0.49 -0.0674 -0.1068 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C11 mock treatment 5.50754481E8 1.27E7 0.2 6.15237038E8 3.87E7 0.87 0.7581 0.8453 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C12 mock treatment 5.75835046E8 3.77E7 0.59 5.83764635E8 7240000.0 0.16 0.5314 0.8708 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C13 compound treatment 3.30853351E8 -2.07E8 -3.23 3.30331852E8 -2.46E8 -5.56 -6.2168 -0.9665 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C14 compound treatment 5.46599505E8 8510000.0 0.13 5.7898788E8 2460000.0 0.06 0.1331 0.9257 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C15 mock treatment 5.90439049E8 5.23E7 0.82 6.21380216E8 4.49E7 1.01 1.2934 0.9942 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C16 mock treatment 5.55876426E8 1.78E7 0.28 5.98957304E8 2.24E7 0.51 0.5544 0.9596 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C17 compound treatment 5.51512973E8 1.34E7 0.21 5.6172716E8 -1.48E7 -0.33 -0.0886 -0.2247 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C18 compound treatment 5.72600154E8 3.45E7 0.54 5.84371005E8 7850000.0 0.18 0.5055 0.893 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C19 compound treatment 5.65201145E8 2.71E7 0.42 6.00212392E8 2.37E7 0.54 0.6771 0.9931 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C20 compound treatment 5.68265488E8 3.02E7 0.47 5.99539919E8 2.3E7 0.52 0.7001 0.9987 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C21 compound treatment 5.61049512E8 2.3E7 0.36 6.10254685E8 3.37E7 0.76 0.7919 0.9405 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C22 compound treatment 5.8914439E8 5.11E7 0.8 5.87028247E8 1.05E7 0.24 0.7302 0.8798 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C23 compound treatment 5.5476822E8 1.67E7 0.26 5.94978017E8 1.85E7 0.42 0.4786 0.9741 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 C24 compound treatment 5.4886612E8 1.08E7 0.17 6.09679559E8 3.32E7 0.75 0.6485 0.8446 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D01 compound treatment 4.8669796E8 -5.14E7 -0.8 5.0500088E8 -7.15E7 -1.62 -1.709 -0.9475 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D02 compound treatment 5.93952241E8 5.59E7 0.87 5.76279726E8 -245000.0 -0.01 0.6113 0.7026 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D03 compound treatment 3.677287E8 -1.7E8 -2.65 3.53656182E8 -2.23E8 -5.04 -5.4379 -0.9552 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D04 compound treatment 5.99990737E8 6.19E7 0.96 6.13585715E8 3.71E7 0.84 1.274 0.9975 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D05 compound treatment 4.88997967E8 -4.91E7 -0.76 5.41793262E8 -3.47E7 -0.78 -1.0957 -0.9999 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D06 compound treatment 5.62407282E8 2.43E7 0.38 6.37603768E8 6.11E7 1.38 1.2439 0.869 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D07 compound treatment 5.8024607E8 4.22E7 0.66 6.25346315E8 4.88E7 1.1 1.2445 0.9693 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D08 compound treatment 5.69627167E8 3.15E7 0.49 6.35572462E8 5.9E7 1.33 1.291 0.9078 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D09 compound treatment 5.7689954E8 3.88E7 0.6 6.00632896E8 2.41E7 0.54 0.8127 0.9987 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D10 compound treatment 5.57790777E8 1.97E7 0.31 6.28785554E8 5.23E7 1.18 1.0521 0.8622 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D11 mock treatment 6.0225504E8 6.42E7 1.0 5.94583014E8 1.81E7 0.41 0.9953 0.9219 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D12 mock treatment 5.6009451E8 2.2E7 0.34 5.95677076E8 1.92E7 0.43 0.5484 0.9933 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D13 compound treatment 4.8084123E8 -5.72E7 -0.89 5.41345328E8 -3.52E7 -0.8 -1.1927 -0.9984 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D14 compound treatment 5.52059905E8 1.4E7 0.22 5.76475517E8 -49600.0 0.0 0.1531 0.7035 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D15 mock treatment 5.8877307E8 5.07E7 0.79 6.1281433E8 3.63E7 0.82 1.1382 0.9998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D16 mock treatment 5.64239123E8 2.61E7 0.41 5.99003363E8 2.25E7 0.51 0.6472 0.994 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D17 compound treatment 5.35567465E8 -2520000.0 -0.04 5.78295247E8 1770000.0 0.04 5.0E-4 0.0092 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D18 compound treatment 5.50127406E8 1.2E7 0.19 5.73395844E8 -3130000.0 -0.07 0.0826 0.4121 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D19 compound treatment 5.48249091E8 1.02E7 0.16 5.82276049E8 5750000.0 0.13 0.2038 0.9952 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D20 compound treatment 5.68178708E8 3.01E7 0.47 5.81006272E8 4480000.0 0.1 0.403 0.8405 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D21 compound treatment 2.63386859E8 -2.75E8 -4.28 3.92753766E8 -1.84E8 -4.15 -5.9623 -0.9999 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D22 compound treatment 5.56662425E8 1.86E7 0.29 5.83144595E8 6620000.0 0.15 0.3103 0.9529 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D23 compound treatment 5.50337731E8 1.22E7 0.19 5.78728025E8 2200000.0 0.05 0.1701 0.8627 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 D24 compound treatment 5.2375365E8 -1.43E7 -0.22 5.78529337E8 2000000.0 0.05 -0.1259 -0.5524 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E01 mock treatment 5.20021384E8 -1.81E7 -0.28 5.96926103E8 2.04E7 0.46 0.127 0.2352 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E02 mock treatment 5.35477003E8 -2610000.0 -0.04 5.45492548E8 -3.1E7 -0.7 -0.5247 -0.7469 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E03 compound treatment 5.24517064E8 -1.36E7 -0.21 5.56479935E8 -2.0E7 -0.45 -0.4698 -0.9398 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E04 compound treatment 5.3677557E8 -1310000.0 -0.02 5.39108155E8 -3.74E7 -0.85 -0.6124 -0.724 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E05 compound treatment 5.29159397E8 -8930000.0 -0.14 5.35866802E8 -4.07E7 -0.92 -0.7481 -0.805 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E06 compound treatment 5.03752165E8 -3.43E7 -0.53 5.12060457E8 -6.45E7 -1.46 -1.4084 -0.9075 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E07 compound treatment 5.09689164E8 -2.84E7 -0.44 5.48923346E8 -2.76E7 -0.62 -0.7539 -0.9858 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E08 compound treatment 5.24410122E8 -1.37E7 -0.21 5.42046337E8 -3.45E7 -0.78 -0.7017 -0.8686 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E09 mock treatment 5.29533111E8 -8560000.0 -0.13 5.50451811E8 -2.61E7 -0.59 -0.5109 -0.8457 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E10 mock treatment 5.46857064E8 8770000.0 0.14 5.86398408E8 9870000.0 0.22 0.2543 0.9722 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E11 compound treatment 5.30882485E8 -7210000.0 -0.11 5.76087325E8 -438000.0 -0.01 -0.0864 -0.7665 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E12 compound treatment 5.15374578E8 -2.27E7 -0.35 5.50747383E8 -2.58E7 -0.58 -0.6621 -0.9714 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E13 compound treatment 5.14986186E8 -2.31E7 -0.36 5.35373159E8 -4.12E7 -0.93 -0.9121 -0.9146 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E14 compound treatment 4.91286054E8 -4.68E7 -0.73 5.41402891E8 -3.51E7 -0.79 -1.0768 -0.9991 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E15 compound treatment 5.13069609E8 -2.5E7 -0.39 5.27932905E8 -4.86E7 -1.1 -1.0521 -0.9029 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E16 compound treatment 5.20561407E8 -1.75E7 -0.27 5.3538622E8 -4.11E7 -0.93 -0.8505 -0.8777 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E17 mock treatment 5.10951181E8 -2.71E7 -0.42 5.30013176E8 -4.65E7 -1.05 -1.0422 -0.9199 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E18 mock treatment 5.26414237E8 -1.17E7 -0.18 5.32309777E8 -4.42E7 -1.0 -0.8352 -0.8223 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E19 compound treatment 5.01546855E8 -3.65E7 -0.57 5.08672643E8 -6.79E7 -1.53 -1.4868 -0.909 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E20 compound treatment 5.24862675E8 -1.32E7 -0.21 5.44439815E8 -3.21E7 -0.73 -0.6584 -0.8734 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E21 compound treatment 5.14646556E8 -2.34E7 -0.37 5.0836531E8 -6.82E7 -1.54 -1.3474 -0.8511 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E22 compound treatment 5.24577578E8 -1.35E7 -0.21 5.16432966E8 -6.01E7 -1.36 -1.1091 -0.8071 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E23 compound treatment 5.2563995E8 -1.24E7 -0.19 5.27168972E8 -4.94E7 -1.12 -0.9259 -0.8178 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 E24 compound treatment 5.15825974E8 -2.23E7 -0.35 5.62635691E8 -1.39E7 -0.31 -0.4672 -0.9988 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F01 mock treatment 5.30835573E8 -7250000.0 -0.11 5.57539955E8 -1.9E7 -0.43 -0.3833 -0.8639 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F02 mock treatment 5.59758841E8 2.17E7 0.34 5.76306119E8 -219000.0 0.0 0.2352 0.6967 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F03 compound treatment 5.40918284E8 2830000.0 0.04 5.7212549E8 -4400000.0 -0.1 -0.0391 -0.36 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F04 compound treatment 5.33016565E8 -5070000.0 -0.08 5.56879165E8 -1.96E7 -0.44 -0.3698 -0.8201 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F05 compound treatment 5.39332231E8 1240000.0 0.02 5.92278045E8 1.58E7 0.36 0.2654 0.7445 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F06 compound treatment 5.7210525E8 3.4E7 0.53 5.96616349E8 2.01E7 0.45 0.6957 0.997 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F07 compound treatment 5.03836313E8 -3.43E7 -0.53 5.32689555E8 -4.38E7 -0.99 -1.0778 -0.9578 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F08 compound treatment 5.45479102E8 7390000.0 0.12 5.49061186E8 -2.75E7 -0.62 -0.3575 -0.5663 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F09 mock treatment 5.59791728E8 2.17E7 0.34 5.64332268E8 -1.22E7 -0.28 0.0442 0.1013 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F10 mock treatment 5.39300757E8 1210000.0 0.02 5.41885838E8 -3.46E7 -0.78 -0.5402 -0.6899 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F11 compound treatment 5.32718802E8 -5370000.0 -0.08 5.42469514E8 -3.41E7 -0.77 -0.6034 -0.7794 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F12 compound treatment 5.51637181E8 1.35E7 0.21 5.23031281E8 -5.35E7 -1.21 -0.7057 -0.575 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F13 compound treatment 5.19319987E8 -1.88E7 -0.29 5.37644839E8 -3.89E7 -0.88 -0.8281 -0.8942 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F14 compound treatment 5.44552522E8 6460000.0 0.1 5.19526233E8 -5.7E7 -1.29 -0.8397 -0.6499 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F15 compound treatment 5.38011285E8 -77900.0 0.0 5.25903537E8 -5.06E7 -1.14 -0.8098 -0.7079 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F16 compound treatment 5.35276798E8 -2810000.0 -0.04 5.5035571E8 -2.62E7 -0.59 -0.4492 -0.7574 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F17 mock treatment 5.33370511E8 -4720000.0 -0.07 5.41361909E8 -3.52E7 -0.79 -0.6139 -0.7692 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F18 mock treatment 5.42915142E8 4830000.0 0.08 5.3388806E8 -4.26E7 -0.96 -0.6282 -0.65 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F19 compound treatment 5.40939035E8 2850000.0 0.04 5.23106148E8 -5.34E7 -1.21 -0.8223 -0.6806 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F20 compound treatment 5.48808084E8 1.07E7 0.17 5.40410428E8 -3.61E7 -0.82 -0.4591 -0.5511 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F21 compound treatment 5.3999793E8 1910000.0 0.03 5.38756669E8 -3.78E7 -0.85 -0.5825 -0.6821 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F22 compound treatment 5.38768117E8 679000.0 0.01 5.26791638E8 -4.97E7 -1.12 -0.7873 -0.7004 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F23 compound treatment 5.38116592E8 27400.0 0.0 5.49980523E8 -2.65E7 -0.6 -0.4239 -0.7066 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 F24 compound treatment 5.09018939E8 -2.91E7 -0.45 5.60113906E8 -1.64E7 -0.37 -0.5824 -0.9951 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G01 compound treatment 5.48913493E8 1.08E7 0.17 5.95136128E8 1.86E7 0.42 0.4166 0.9194 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G02 compound treatment 5.11824282E8 -2.63E7 -0.41 5.44436195E8 -3.21E7 -0.73 -0.8021 -0.9633 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G03 mock treatment 5.54402676E8 1.63E7 0.25 5.96030378E8 1.95E7 0.44 0.4914 0.9657 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G04 mock treatment 5.48112715E8 1.0E7 0.16 5.71129265E8 -5400000.0 -0.12 0.0242 0.122 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G05 compound treatment 5.69390488E8 3.13E7 0.49 5.51822237E8 -2.47E7 -0.56 -0.05 -0.0675 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G06 compound treatment 5.69404092E8 3.13E7 0.49 6.07309353E8 3.08E7 0.7 0.8369 0.9849 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G07 compound treatment 5.31202676E8 -6890000.0 -0.11 5.73109937E8 -3420000.0 -0.08 -0.1304 -0.987 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G08 compound treatment 5.85073885E8 4.7E7 0.73 5.73382817E8 -3140000.0 -0.07 0.4673 0.6355 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G09 compound treatment 5.80619755E8 4.25E7 0.66 5.94580423E8 1.81E7 0.41 0.757 0.9729 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G10 compound treatment 5.70192301E8 3.21E7 0.5 5.71699347E8 -4830000.0 -0.11 0.2765 0.5402 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G11 compound treatment 5.57727022E8 1.96E7 0.31 5.64306009E8 -1.22E7 -0.28 0.021 0.051 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G12 compound treatment 5.65120328E8 2.7E7 0.42 5.84289361E8 7760000.0 0.18 0.4218 0.9247 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G13 compound treatment 5.53539586E8 1.55E7 0.24 5.53474117E8 -2.31E7 -0.52 -0.1982 -0.3454 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G14 compound treatment 5.41815005E8 3730000.0 0.06 5.81301774E8 4780000.0 0.11 0.1174 0.9576 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G15 compound treatment 5.63052578E8 2.5E7 0.39 5.66260771E8 -1.03E7 -0.23 0.1109 0.245 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G16 compound treatment 5.46936891E8 8850000.0 0.14 5.66322932E8 -1.02E7 -0.23 -0.0656 -0.2442 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G17 compound treatment 5.49277078E8 1.12E7 0.17 5.84292573E8 7770000.0 0.18 0.2474 1.0 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G18 compound treatment 5.53526685E8 1.54E7 0.24 5.66767409E8 -9760000.0 -0.22 0.0141 0.0432 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G19 mock treatment 5.37205932E8 -883000.0 -0.01 5.83692998E8 7170000.0 0.16 0.1048 0.6447 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G20 mock treatment 5.42153353E8 4060000.0 0.06 5.88575551E8 1.21E7 0.27 0.2373 0.8488 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G21 compound treatment 5.27487698E8 -1.06E7 -0.17 5.76104959E8 -420000.0 -0.01 -0.1235 -0.7465 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G22 compound treatment 5.22947009E8 -1.51E7 -0.24 5.61519083E8 -1.5E7 -0.34 -0.4066 -0.9842 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G23 compound treatment 5.41212023E8 3120000.0 0.05 5.59469463E8 -1.71E7 -0.39 -0.2382 -0.613 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 G24 compound treatment 5.22965686E8 -1.51E7 -0.24 5.78162894E8 1640000.0 0.04 -0.1404 -0.5888 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H01 compound treatment 5.73630608E8 3.55E7 0.55 5.67313502E8 -9210000.0 -0.21 0.2442 0.413 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H02 compound treatment 5.21593759E8 -1.65E7 -0.26 5.55297155E8 -2.12E7 -0.48 -0.5209 -0.9572 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H03 mock treatment 5.97779847E8 5.97E7 0.93 6.09227709E8 3.27E7 0.74 1.18 0.9935 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H04 mock treatment 6.01762153E8 6.37E7 0.99 6.0320123E8 2.67E7 0.6 1.1276 0.9715 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H05 compound treatment 5.96503815E8 5.84E7 0.91 6.39974424E8 6.34E7 1.43 1.6573 0.9759 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H06 compound treatment 5.54365583E8 1.63E7 0.25 6.08002236E8 3.15E7 0.71 0.6823 0.9034 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H07 compound treatment 5.41257249E8 3170000.0 0.05 6.42283753E8 6.58E7 1.49 1.0858 0.7302 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H08 mock treatment 5.56952782E8 1.89E7 0.29 5.78752843E8 2230000.0 0.05 0.2434 0.8164 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H09 compound treatment 5.83507544E8 4.54E7 0.71 5.96083263E8 1.96E7 0.44 0.8128 0.9744 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H10 mock treatment 5.64246868E8 2.62E7 0.41 5.93657173E8 1.71E7 0.39 0.5619 0.9997 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H11 compound treatment 5.78784434E8 4.07E7 0.63 6.09372625E8 3.28E7 0.74 0.9731 0.9969 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H12 mock treatment 5.57605109E8 1.95E7 0.3 6.03426824E8 2.69E7 0.61 0.6449 0.9487 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H13 compound treatment 5.60844284E8 2.28E7 0.35 6.06047872E8 2.95E7 0.67 0.7224 0.9562 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H14 mock treatment 5.80968857E8 4.29E7 0.67 5.73949322E8 -2580000.0 -0.06 0.4311 0.643 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H15 compound treatment 5.7219284E8 3.41E7 0.53 6.12258286E8 3.57E7 0.81 0.9467 0.9793 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H16 mock treatment 5.72211042E8 3.41E7 0.53 5.86656555E8 1.01E7 0.23 0.5377 0.9292 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H17 compound treatment 5.67935886E8 2.98E7 0.46 6.05391603E8 2.89E7 0.65 0.79 0.9862 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H18 mock treatment 5.52295906E8 1.42E7 0.22 6.15722744E8 3.92E7 0.89 0.7829 0.8574 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H19 mock treatment 5.75242082E8 3.72E7 0.58 5.90721134E8 1.42E7 0.32 0.6361 0.9613 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H20 mock treatment 5.66352275E8 2.83E7 0.44 5.6563028E8 -1.09E7 -0.25 0.1372 0.272 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H21 compound treatment 5.64445075E8 2.64E7 0.41 5.97396922E8 2.09E7 0.47 0.6238 0.9976 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H22 mock treatment 5.57793813E8 1.97E7 0.31 6.05518445E8 2.9E7 0.66 0.6804 0.9403 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H23 compound treatment 4.4788839E8 -9.02E7 -1.4 5.41779779E8 -3.47E7 -0.79 -1.5487 -0.9622 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 H24 mock treatment 5.35335926E8 -2750000.0 -0.04 5.65029511E8 -1.15E7 -0.26 -0.214 -0.8128 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I01 compound treatment 5.12263237E8 -2.58E7 -0.4 5.63850535E8 -1.27E7 -0.29 -0.487 -0.9862 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I02 compound treatment 5.16294957E8 -2.18E7 -0.34 5.14684026E8 -6.18E7 -1.4 -1.2283 -0.854 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I03 compound treatment 5.02980314E8 -3.51E7 -0.55 4.80869274E8 -9.57E7 -2.16 -1.9153 -0.8589 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I04 compound treatment 5.14106501E8 -2.4E7 -0.37 5.37370259E8 -3.92E7 -0.88 -0.8899 -0.9264 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I05 mock treatment 5.272131E8 -1.09E7 -0.17 5.37658845E8 -3.89E7 -0.88 -0.7409 -0.8282 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I06 mock treatment 5.37325634E8 -764000.0 -0.01 5.34916196E8 -4.16E7 -0.94 -0.6733 -0.716 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I07 compound treatment 5.16105061E8 -2.2E7 -0.34 5.58952317E8 -1.76E7 -0.4 -0.523 -0.9973 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I08 compound treatment 5.2794836E8 -1.01E7 -0.16 5.6608473E8 -1.04E7 -0.24 -0.2785 -0.981 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I09 compound treatment 5.370276E8 -1060000.0 -0.02 5.35972791E8 -4.06E7 -0.92 -0.6597 -0.7197 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I10 compound treatment 5.28022395E8 -1.01E7 -0.16 5.37084138E8 -3.94E7 -0.89 -0.7412 -0.8189 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I11 compound treatment 5.16194549E8 -2.19E7 -0.34 5.52393485E8 -2.41E7 -0.55 -0.6268 -0.9744 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I12 compound treatment 5.03153789E8 -3.49E7 -0.54 5.247092E8 -5.18E7 -1.17 -1.2128 -0.9392 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I13 compound treatment 5.18153275E8 -1.99E7 -0.31 5.50357875E8 -2.62E7 -0.59 -0.6377 -0.9548 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I14 compound treatment 5.49148232E8 1.11E7 0.17 5.58872757E8 -1.77E7 -0.4 -0.1603 -0.3689 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I15 compound treatment 5.5823946E8 2.02E7 0.31 5.5034169E8 -2.62E7 -0.59 -0.1965 -0.2934 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I16 compound treatment 4.9643088E8 -4.17E7 -0.65 5.50463338E8 -2.61E7 -0.59 -0.8753 -0.9988 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I17 compound treatment 4.79805273E8 -5.83E7 -0.91 5.46625885E8 -2.99E7 -0.68 -1.1197 -0.9894 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I18 compound treatment 4.99612781E8 -3.85E7 -0.6 5.56398876E8 -2.01E7 -0.45 -0.7454 -0.9907 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I19 compound treatment 4.42923653E8 -9.52E7 -1.48 5.58630688E8 -1.79E7 -0.4 -1.3341 -0.8683 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I20 compound treatment 4.94675988E8 -4.34E7 -0.68 5.56034632E8 -2.05E7 -0.46 -0.8056 -0.9829 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I21 mock treatment 4.81495485E8 -5.66E7 -0.88 5.61484825E8 -1.5E7 -0.34 -0.8637 -0.9142 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I22 mock treatment 5.03975659E8 -3.41E7 -0.53 5.79265071E8 2740000.0 0.06 -0.3319 -0.6205 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I23 compound treatment 4.56613604E8 -8.15E7 -1.27 5.38520721E8 -3.8E7 -0.86 -1.5047 -0.9819 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 I24 compound treatment 4.58594666E8 -7.95E7 -1.24 5.25032372E8 -5.15E7 -1.16 -1.6984 -0.9995 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J01 compound treatment 4.95481754E8 -4.26E7 -0.66 6.07323892E8 3.08E7 0.7 0.0229 0.0238 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J02 mock treatment 5.15511925E8 -2.26E7 -0.35 5.68740893E8 -7780000.0 -0.18 -0.3731 -0.9487 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J03 compound treatment 5.13643738E8 -2.44E7 -0.38 5.92722125E8 1.62E7 0.37 -0.0104 -0.0197 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J04 mock treatment 5.02366293E8 -3.57E7 -0.56 5.64497563E8 -1.2E7 -0.27 -0.5857 -0.9457 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J05 mock treatment 5.00140249E8 -3.79E7 -0.59 5.61645828E8 -1.49E7 -0.34 -0.6557 -0.9643 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J06 mock treatment 4.87268371E8 -5.08E7 -0.79 5.79359512E8 2830000.0 0.06 -0.5144 -0.6478 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J07 compound treatment 4.66311942E8 -7.18E7 -1.12 6.16063088E8 3.95E7 0.89 -0.1587 -0.1109 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J08 mock treatment 5.00035101E8 -3.81E7 -0.59 6.30968727E8 5.44E7 1.23 0.4509 0.3302 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J09 compound treatment 4.92097297E8 -4.6E7 -0.72 5.65622025E8 -1.09E7 -0.25 -0.6808 -0.8987 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J10 mock treatment 4.90676911E8 -4.74E7 -0.74 5.65924539E8 -1.06E7 -0.24 -0.6916 -0.8908 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J11 compound treatment 4.83423734E8 -5.47E7 -0.85 5.61307957E8 -1.52E7 -0.34 -0.8453 -0.9205 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J12 mock treatment 4.74004331E8 -6.41E7 -1.0 5.91347013E8 1.48E7 0.33 -0.469 -0.4454 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J13 compound treatment 4.61975171E8 -7.61E7 -1.19 5.78551051E8 2030000.0 0.05 -0.8059 -0.6793 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J14 mock treatment 4.79259957E8 -5.88E7 -0.92 5.51714792E8 -2.48E7 -0.56 -1.0444 -0.9722 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J15 compound treatment 4.78588051E8 -5.95E7 -0.93 5.65185837E8 -1.13E7 -0.26 -0.8365 -0.87 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J16 mock treatment 4.91878928E8 -4.62E7 -0.72 5.85693204E8 9170000.0 0.21 -0.3624 -0.4839 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J17 compound treatment 4.20481265E8 -1.18E8 -1.83 5.47073836E8 -2.95E7 -0.67 -1.766 -0.9061 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J18 mock treatment 4.82531758E8 -5.56E7 -0.87 5.95511152E8 1.9E7 0.43 -0.3085 -0.3194 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J19 compound treatment 4.5173962E8 -8.63E7 -1.34 5.63503139E8 -1.3E7 -0.29 -1.1591 -0.8419 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J20 mock treatment 4.77800568E8 -6.03E7 -0.94 5.72886467E8 -3640000.0 -0.08 -0.7222 -0.7661 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J21 mock treatment 4.91314012E8 -4.68E7 -0.73 5.80461155E8 3940000.0 0.09 -0.4523 -0.6162 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J22 mock treatment 5.00398793E8 -3.77E7 -0.59 5.68596253E8 -7930000.0 -0.18 -0.5418 -0.8827 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J23 compound treatment 3.96128139E8 -1.42E8 -2.21 4.7966299E8 -9.69E7 -2.19 -3.1115 -1.0 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 J24 mock treatment 4.8114965E8 -5.69E7 -0.89 5.35055078E8 -4.15E7 -0.94 -1.2898 -0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K01 compound treatment 4.82097151E8 -5.6E7 -0.87 4.64544323E8 -1.12E8 -2.53 -2.4062 -0.8989 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K02 compound treatment 5.29447338E8 -8640000.0 -0.13 4.80805664E8 -9.57E7 -2.16 -1.6248 -0.7497 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K03 compound treatment 4.69265271E8 -6.88E7 -1.07 4.67710567E8 -1.09E8 -2.46 -2.4969 -0.9308 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K04 compound treatment 5.22816132E8 -1.53E7 -0.24 5.15823185E8 -6.07E7 -1.37 -1.1383 -0.8175 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K05 compound treatment 5.13186238E8 -2.49E7 -0.39 5.20865257E8 -5.57E7 -1.26 -1.1638 -0.8841 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K06 compound treatment 4.99627197E8 -3.85E7 -0.6 5.55413687E8 -2.11E7 -0.48 -0.761 -0.9936 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K07 mock treatment 5.22596417E8 -1.55E7 -0.24 5.27550935E8 -4.9E7 -1.11 -0.9533 -0.8415 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K08 mock treatment 5.3035769E8 -7730000.0 -0.12 6.03129222E8 2.66E7 0.6 0.34 0.5545 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K09 compound treatment 5.24981149E8 -1.31E7 -0.2 5.42348712E8 -3.42E7 -0.77 -0.6905 -0.8643 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K10 compound treatment 5.40460762E8 2370000.0 0.04 5.74848719E8 -1680000.0 -0.04 -7.0E-4 -0.0127 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K11 compound treatment 5.00255849E8 -3.78E7 -0.59 5.12781301E8 -6.37E7 -1.44 -1.4354 -0.9222 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K12 compound treatment 5.14633777E8 -2.35E7 -0.37 5.34915956E8 -4.16E7 -0.94 -0.9233 -0.9152 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K13 compound treatment 5.13034662E8 -2.51E7 -0.39 5.30757516E8 -4.58E7 -1.03 -1.0073 -0.9112 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K14 compound treatment 5.10799753E8 -2.73E7 -0.43 5.53053843E8 -2.35E7 -0.53 -0.6756 -0.994 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K15 mock treatment 5.41548661E8 3460000.0 0.05 5.67214298E8 -9310000.0 -0.21 -0.1107 -0.5096 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K16 mock treatment 5.28073596E8 -1.0E7 -0.16 5.73388578E8 -3140000.0 -0.07 -0.1604 -0.9363 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K17 compound treatment 5.2247062E8 -1.56E7 -0.24 5.39907204E8 -3.66E7 -0.83 -0.7572 -0.8778 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K18 compound treatment 5.20717341E8 -1.74E7 -0.27 5.52212166E8 -2.43E7 -0.55 -0.5799 -0.9467 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K19 compound treatment 4.90951475E8 -4.71E7 -0.73 5.53849899E8 -2.27E7 -0.51 -0.8815 -0.9845 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K20 compound treatment 5.48111539E8 1.0E7 0.16 5.78436765E8 1910000.0 0.04 0.1409 0.8701 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K21 compound treatment 5.21695545E8 -1.64E7 -0.26 5.55097501E8 -2.14E7 -0.48 -0.523 -0.9553 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K22 compound treatment 5.21453491E8 -1.66E7 -0.26 5.60039017E8 -1.65E7 -0.37 -0.4467 -0.9842 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K23 mock treatment 5.48965348E8 1.09E7 0.17 5.54232449E8 -2.23E7 -0.5 -0.2365 -0.4449 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 K24 mock treatment 5.32099028E8 -5990000.0 -0.09 5.61866202E8 -1.47E7 -0.33 -0.3002 -0.8723 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L01 compound treatment 4.97955318E8 -4.01E7 -0.63 5.58770742E8 -1.78E7 -0.4 -0.7258 -0.977 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L02 mock treatment 5.11937839E8 -2.62E7 -0.41 6.26160456E8 4.96E7 1.12 0.5052 0.4233 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L03 compound treatment 5.45138808E8 7050000.0 0.11 5.67858906E8 -8670000.0 -0.2 -0.0608 -0.271 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L04 mock treatment 5.17357356E8 -2.07E7 -0.32 6.05989107E8 2.95E7 0.67 0.2425 0.3277 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L05 compound treatment 4.82231954E8 -5.59E7 -0.87 5.4061496E8 -3.59E7 -0.81 -1.1891 -0.9994 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L06 mock treatment 5.20474649E8 -1.76E7 -0.27 6.00595337E8 2.41E7 0.54 0.1907 0.3129 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L07 mock treatment 5.40368831E8 2280000.0 0.04 5.92130002E8 1.56E7 0.35 0.2745 0.7744 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L08 mock treatment 5.11122683E8 -2.7E7 -0.42 5.92642065E8 1.61E7 0.36 -0.0394 -0.071 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L09 compound treatment 4.86117782E8 -5.2E7 -0.81 5.5241563E8 -2.41E7 -0.54 -0.9577 -0.9814 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L10 mock treatment 5.17938277E8 -2.02E7 -0.31 5.97126869E8 2.06E7 0.47 0.1073 0.1911 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L11 compound treatment 5.54088073E8 1.6E7 0.25 5.99064152E8 2.25E7 0.51 0.5364 0.9459 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L12 mock treatment 5.44102905E8 6010000.0 0.09 6.04538267E8 2.8E7 0.63 0.5139 0.803 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L13 compound treatment 5.2022068E8 -1.79E7 -0.28 5.78999179E8 2470000.0 0.06 -0.1573 -0.554 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L14 mock treatment 5.62369932E8 2.43E7 0.38 6.1301527E8 3.65E7 0.82 0.8506 0.9375 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L15 mock treatment 5.64618904E8 2.65E7 0.41 6.02133087E8 2.56E7 0.58 0.7014 0.9864 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L16 mock treatment 5.68427945E8 3.03E7 0.47 5.98089185E8 2.16E7 0.49 0.6788 0.9999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L17 compound treatment 5.60735479E8 2.26E7 0.35 6.36912924E8 6.04E7 1.36 1.2145 0.8616 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L18 mock treatment 5.67611239E8 2.95E7 0.46 5.83665592E8 7140000.0 0.16 0.4393 0.9014 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L19 compound treatment 5.48907591E8 1.08E7 0.17 5.95966425E8 1.94E7 0.44 0.4298 0.9134 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L20 mock treatment 5.40910489E8 2820000.0 0.04 5.92012923E8 1.55E7 0.35 0.2786 0.7897 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L21 compound treatment 5.43742785E8 5650000.0 0.09 5.66213952E8 -1.03E7 -0.23 -0.1025 -0.4115 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L22 mock treatment 5.50013001E8 1.19E7 0.19 6.06587572E8 3.01E7 0.68 0.6117 0.8685 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L23 mock treatment 5.55135989E8 1.7E7 0.27 5.61522904E8 -1.5E7 -0.34 -0.052 -0.1207 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 L24 mock treatment 5.22894224E8 -1.52E7 -0.24 5.64187554E8 -1.23E7 -0.28 -0.3645 -0.9967 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M01 compound treatment 4.98388621E8 -3.97E7 -0.62 5.34462881E8 -4.21E7 -0.95 -1.1094 -0.9783 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M02 compound treatment 5.43544372E8 5460000.0 0.08 5.26632072E8 -4.99E7 -1.13 -0.7372 -0.652 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M03 compound treatment 5.23283883E8 -1.48E7 -0.23 5.49077925E8 -2.74E7 -0.62 -0.6017 -0.9092 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M04 compound treatment 5.60041681E8 2.2E7 0.34 5.76306679E8 -218000.0 0.0 0.2383 0.6968 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M05 compound treatment 5.32682971E8 -5410000.0 -0.08 5.37883383E8 -3.86E7 -0.87 -0.6771 -0.7717 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M06 compound treatment 5.32026709E8 -6060000.0 -0.09 5.73215564E8 -3310000.0 -0.07 -0.1197 -0.9933 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M07 compound treatment 5.50918621E8 1.28E7 0.2 5.70766879E8 -5760000.0 -0.13 0.0493 0.2067 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M08 compound treatment 5.28775758E8 -9310000.0 -0.15 5.50928452E8 -2.56E7 -0.58 -0.5116 -0.8579 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M09 mock treatment 5.70452795E8 3.24E7 0.5 5.59058364E8 -1.75E7 -0.39 0.0773 0.1208 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M10 mock treatment 5.45378867E8 7290000.0 0.11 5.4878668E8 -2.77E7 -0.63 -0.363 -0.5698 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M11 compound treatment 5.57531592E8 1.94E7 0.3 5.18830153E8 -5.77E7 -1.3 -0.7079 -0.5288 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M12 compound treatment 4.88576529E8 -4.95E7 -0.77 4.72672526E8 -1.04E8 -2.35 -2.205 -0.8925 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M13 mock treatment 5.6313766E8 2.5E7 0.39 5.62354346E8 -1.42E7 -0.32 0.0494 0.0979 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M14 mock treatment 5.60700548E8 2.26E7 0.35 5.44252127E8 -3.23E7 -0.73 -0.2667 -0.3293 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M15 compound treatment 5.43229297E8 5140000.0 0.08 5.40025926E8 -3.65E7 -0.82 -0.5267 -0.6355 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M16 compound treatment 5.28774386E8 -9310000.0 -0.15 5.28359338E8 -4.82E7 -1.09 -0.8723 -0.7943 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M17 compound treatment 5.14959262E8 -2.31E7 -0.36 5.472326E8 -2.93E7 -0.66 -0.7229 -0.9591 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M18 compound treatment 5.16537424E8 -2.16E7 -0.34 5.33039952E8 -4.35E7 -0.98 -0.9323 -0.8977 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M19 compound treatment 5.15547397E8 -2.25E7 -0.35 5.5674465E8 -1.98E7 -0.45 -0.5644 -0.9929 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M20 compound treatment 4.9244605E8 -4.56E7 -0.71 5.06499598E8 -7.0E7 -1.58 -1.6218 -0.9348 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M21 compound treatment 5.35716998E8 -2370000.0 -0.04 5.6660953E8 -9920000.0 -0.22 -0.1846 -0.8127 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M22 compound treatment 4.90266537E8 -4.78E7 -0.74 5.27818743E8 -4.87E7 -1.1 -1.3051 -0.9819 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M23 compound treatment 5.31944657E8 -6140000.0 -0.1 5.39550259E8 -3.7E7 -0.84 -0.6586 -0.783 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 M24 compound treatment 4.9326769E8 -4.48E7 -0.7 5.1336706E8 -6.32E7 -1.43 -1.503 -0.9459 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N01 compound treatment 5.05672249E8 -3.24E7 -0.5 5.98946068E8 2.24E7 0.51 0.0013 0.0018 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N02 mock treatment 5.44824813E8 6740000.0 0.1 6.11953473E8 3.54E7 0.8 0.6404 0.793 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N03 compound treatment 5.62807416E8 2.47E7 0.39 6.32468003E8 5.59E7 1.26 1.1662 0.8824 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N04 mock treatment 5.73864357E8 3.58E7 0.56 6.02845126E8 2.63E7 0.59 0.8146 0.9995 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N05 compound treatment 5.07844667E8 -3.02E7 -0.47 5.96194696E8 1.97E7 0.44 -0.0188 -0.029 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N06 mock treatment 5.30783513E8 -7310000.0 -0.11 6.10969535E8 3.44E7 0.78 0.47 0.5974 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N07 compound treatment 5.56566913E8 1.85E7 0.29 5.90793146E8 1.43E7 0.32 0.4315 0.9984 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N08 mock treatment 5.40041765E8 1950000.0 0.03 6.0700307E8 3.05E7 0.69 0.5086 0.7376 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N09 mock treatment 5.60444191E8 2.24E7 0.35 5.98649977E8 2.21E7 0.5 0.5998 0.9844 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N10 mock treatment 5.71599506E8 3.35E7 0.52 6.18343183E8 4.18E7 0.95 1.0374 0.9608 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N11 compound treatment 5.46877594E8 8790000.0 0.14 5.75704747E8 -820000.0 -0.02 0.0837 0.6058 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N12 mock treatment 5.51348589E8 1.33E7 0.21 5.76111503E8 -414000.0 -0.01 0.1394 0.6744 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N13 mock treatment 5.6137615E8 2.33E7 0.36 5.98810289E8 2.23E7 0.5 0.6126 0.987 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N14 mock treatment 5.47736689E8 9650000.0 0.15 5.78791148E8 2270000.0 0.05 0.1425 0.8974 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N15 compound treatment 5.54188395E8 1.61E7 0.25 5.51852183E8 -2.47E7 -0.56 -0.217 -0.3549 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N16 mock treatment 5.35953741E8 -2140000.0 -0.03 5.80132491E8 3610000.0 0.08 0.0341 0.3876 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N17 compound treatment 5.63015146E8 2.49E7 0.39 5.76173096E8 -352000.0 -0.01 0.2689 0.6925 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N18 mock treatment 5.4144329E8 3350000.0 0.05 5.6241676E8 -1.41E7 -0.32 -0.1885 -0.5835 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N19 compound treatment 5.28621292E8 -9470000.0 -0.15 5.51972097E8 -2.46E7 -0.55 -0.4967 -0.865 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N20 mock treatment 5.43209189E8 5120000.0 0.08 5.78607456E8 2080000.0 0.05 0.0897 0.9683 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N21 compound treatment 5.17061788E8 -2.1E7 -0.33 5.56414256E8 -2.01E7 -0.45 -0.553 -0.9871 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N22 mock treatment 5.29731459E8 -8360000.0 -0.13 5.67497425E8 -9030000.0 -0.2 -0.2363 -0.9764 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N23 compound treatment 5.27454264E8 -1.06E7 -0.17 5.44728342E8 -3.18E7 -0.72 -0.6253 -0.8479 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 N24 mock treatment 5.0270929E8 -3.54E7 -0.55 5.35911423E8 -4.06E7 -0.92 -1.0387 -0.9702 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O01 compound treatment 5.59780522E8 2.17E7 0.34 5.50981143E8 -2.55E7 -0.58 -0.1693 -0.2531 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O02 compound treatment 5.24485505E8 -1.36E7 -0.21 5.46592917E8 -2.99E7 -0.68 -0.6282 -0.8861 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O03 compound treatment 5.39299314E8 1210000.0 0.02 5.45425979E8 -3.11E7 -0.7 -0.4837 -0.6879 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O04 compound treatment 5.31892052E8 -6200000.0 -0.1 5.35608242E8 -4.09E7 -0.92 -0.7221 -0.7767 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O05 compound treatment 5.29687554E8 -8400000.0 -0.13 5.490808E8 -2.74E7 -0.62 -0.5311 -0.8379 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O06 compound treatment 5.4528063E8 7190000.0 0.11 5.39186965E8 -3.73E7 -0.84 -0.5175 -0.6079 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O07 compound treatment 5.38241364E8 152000.0 0.0 5.85854654E8 9330000.0 0.21 0.1508 0.715 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O08 compound treatment 5.25317276E8 -1.28E7 -0.2 5.3323266E8 -4.33E7 -0.98 -0.8325 -0.8338 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O09 compound treatment 5.47717564E8 9630000.0 0.15 5.71222206E8 -5300000.0 -0.12 0.0213 0.111 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O10 compound treatment 5.35119458E8 -2970000.0 -0.05 5.49303737E8 -2.72E7 -0.62 -0.4677 -0.7581 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O11 mock treatment 5.20703636E8 -1.74E7 -0.27 5.79586944E8 3060000.0 0.07 -0.1426 -0.51 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O12 mock treatment 5.52777039E8 1.47E7 0.23 5.56066909E8 -2.05E7 -0.46 -0.1652 -0.3202 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O13 compound treatment 5.3899556E8 906000.0 0.01 5.5187352E8 -2.47E7 -0.56 -0.384 -0.689 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O14 compound treatment 5.10589293E8 -2.75E7 -0.43 5.73656613E8 -2870000.0 -0.06 -0.3487 -0.805 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O15 compound treatment 5.06800553E8 -3.13E7 -0.49 5.39839717E8 -3.67E7 -0.83 -0.9309 -0.9679 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O16 compound treatment 4.98036898E8 -4.01E7 -0.62 5.35702523E8 -4.08E7 -0.92 -1.0935 -0.9818 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O17 compound treatment 5.16303651E8 -2.18E7 -0.34 5.38449721E8 -3.81E7 -0.86 -0.8484 -0.9172 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O18 compound treatment 5.16092595E8 -2.2E7 -0.34 5.37375245E8 -3.91E7 -0.88 -0.8679 -0.9147 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O19 compound treatment 5.22216526E8 -1.59E7 -0.25 5.42535296E8 -3.4E7 -0.77 -0.718 -0.8897 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O20 compound treatment 5.11117211E8 -2.7E7 -0.42 5.18635209E8 -5.79E7 -1.31 -1.2222 -0.8894 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O21 compound treatment 5.1959831E8 -1.85E7 -0.29 5.42962044E8 -3.36E7 -0.76 -0.74 -0.9121 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O22 compound treatment 5.08608681E8 -2.95E7 -0.46 5.36665134E8 -3.99E7 -0.9 -0.9617 -0.9511 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O23 compound treatment 5.09147931E8 -2.89E7 -0.45 5.39140641E8 -3.74E7 -0.84 -0.9162 -0.9567 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 O24 compound treatment 5.10586677E8 -2.75E7 -0.43 5.17951362E8 -5.86E7 -1.32 -1.239 -0.8905 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P01 compound treatment 5.40569092E8 2480000.0 0.04 6.03372437E8 2.68E7 0.61 0.4564 0.7506 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P02 mock treatment 5.46980599E8 8890000.0 0.14 5.58352811E8 -1.82E7 -0.41 -0.1925 -0.4441 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P03 compound treatment 5.05540253E8 -3.25E7 -0.51 5.50249163E8 -2.63E7 -0.59 -0.7784 -0.9969 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P04 mock treatment 5.15978402E8 -2.21E7 -0.34 5.73864973E8 -2660000.0 -0.06 -0.286 -0.8182 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P05 compound treatment 5.47912105E8 9820000.0 0.15 6.11827778E8 3.53E7 0.8 0.6723 0.8276 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P06 mock treatment 5.41811703E8 3720000.0 0.06 5.62428376E8 -1.41E7 -0.32 -0.1843 -0.5691 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P07 compound treatment 5.85849731E8 4.78E7 0.74 5.68593712E8 -7930000.0 -0.18 0.3993 0.5218 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P08 mock treatment 5.67249625E8 2.92E7 0.45 5.72955778E8 -3570000.0 -0.08 0.2641 0.5726 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P09 compound treatment 5.27678902E8 -1.04E7 -0.16 5.6959037E8 -6930000.0 -0.16 -0.2255 -0.9999 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P10 mock treatment 5.24986445E8 -1.31E7 -0.2 5.71797167E8 -4730000.0 -0.11 -0.2199 -0.9544 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P11 mock treatment 5.52705264E8 1.46E7 0.23 5.71403072E8 -5120000.0 -0.12 0.0791 0.3098 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P12 mock treatment 5.48897479E8 1.08E7 0.17 5.74109586E8 -2420000.0 -0.05 0.0804 0.4545 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P13 compound treatment 5.38008122E8 -81100.0 0.0 5.66650731E8 -9870000.0 -0.22 -0.1587 -0.7111 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P14 mock treatment 5.39439147E8 1350000.0 0.02 5.37735761E8 -3.88E7 -0.88 -0.605 -0.6899 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P15 compound treatment 5.54378043E8 1.63E7 0.25 5.75364622E8 -1160000.0 -0.03 0.1609 0.6307 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P16 mock treatment 5.27115194E8 -1.1E7 -0.17 5.66392818E8 -1.01E7 -0.23 -0.2828 -0.9896 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P17 compound treatment 5.33215791E8 -4870000.0 -0.08 5.42084374E8 -3.44E7 -0.78 -0.6041 -0.7724 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P18 mock treatment 5.35074752E8 -3010000.0 -0.05 5.44554627E8 -3.2E7 -0.72 -0.5441 -0.7515 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P19 compound treatment 5.40556591E8 2470000.0 0.04 5.52767794E8 -2.38E7 -0.54 -0.3525 -0.6548 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P20 mock treatment 5.48487435E8 1.04E7 0.16 5.47911298E8 -2.86E7 -0.65 -0.3427 -0.5141 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P21 compound treatment 5.16273923E8 -2.18E7 -0.34 5.44805437E8 -3.17E7 -0.72 -0.7472 -0.9418 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P22 mock treatment 5.21208783E8 -1.69E7 -0.26 5.70877745E8 -5650000.0 -0.13 -0.2762 -0.9449 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P23 compound treatment 5.17076239E8 -2.1E7 -0.33 5.48978567E8 -2.75E7 -0.62 -0.6716 -0.9549 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.2283 P24 mock treatment 5.16947865E8 -2.11E7 -0.33 5.29217067E8 -4.73E7 -1.07 -0.9889 -0.8839 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A01 mock treatment 1.33522564E8 -4.13E8 -6.44 6.12107836E8 2.42E7 0.55 -4.1669 -0.6448 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A02 mock treatment 2.33564472E8 -3.13E8 -4.88 6.31274579E8 4.33E7 0.98 -2.7587 -0.5541 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A03 mock treatment 3.12876909E8 -2.34E8 -3.65 5.98986728E8 1.11E7 0.25 -2.4012 -0.6571 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A04 mock treatment 3.76820487E8 -1.7E8 -2.65 6.1066344E8 2.27E7 0.51 -1.5103 -0.5596 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A05 mock treatment 3.91238272E8 -1.56E8 -2.43 6.13768033E8 2.58E7 0.58 -1.3019 -0.5219 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A06 mock treatment 4.16392386E8 -1.31E8 -2.03 5.93559987E8 5630000.0 0.13 -1.3478 -0.6615 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A07 mock treatment 4.38385863E8 -1.09E8 -1.69 5.82909611E8 -5020000.0 -0.11 -1.2758 -0.7528 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A08 mock treatment 4.61575366E8 -8.54E7 -1.33 5.88130624E8 204000.0 0.0 -0.9369 -0.7046 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A09 mock treatment 5.05432316E8 -4.15E7 -0.65 5.88707221E8 781000.0 0.02 -0.4447 -0.6875 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A10 mock treatment 5.33917935E8 -1.3E7 -0.2 5.94348175E8 6420000.0 0.15 -0.0408 -0.1635 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A11 mock treatment 5.44414326E8 -2520000.0 -0.04 5.93270177E8 5340000.0 0.12 0.0576 0.4535 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A12 mock treatment 5.42070212E8 -4870000.0 -0.08 5.97881377E8 9960000.0 0.22 0.1055 0.4442 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A13 mock treatment 5.34455422E8 -1.25E7 -0.19 5.99557023E8 1.16E7 0.26 0.0484 0.148 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A14 mock treatment 5.3545608E8 -1.15E7 -0.18 5.97833498E8 9910000.0 0.22 0.0319 0.1112 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A15 mock treatment 5.57433358E8 1.05E7 0.16 5.51130637E8 -3.68E7 -0.83 -0.4724 -0.5574 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A16 mock treatment 5.4078601E8 -6150000.0 -0.1 5.6569483E8 -2.22E7 -0.5 -0.423 -0.8271 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A17 mock treatment 5.44188666E8 -2750000.0 -0.04 5.5888419E8 -2.9E7 -0.66 -0.4944 -0.7517 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A18 mock treatment 5.55060859E8 8120000.0 0.13 5.76720627E8 -1.12E7 -0.25 -0.0896 -0.3166 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A19 mock treatment 5.39317833E8 -7620000.0 -0.12 5.64770402E8 -2.32E7 -0.52 -0.454 -0.846 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A20 mock treatment 5.55000224E8 8060000.0 0.13 5.67314639E8 -2.06E7 -0.47 -0.2406 -0.4987 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A21 mock treatment 5.71863969E8 2.49E7 0.39 5.64313899E8 -2.36E7 -0.53 -0.1028 -0.1558 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A22 mock treatment 5.47890636E8 952000.0 0.01 5.57013086E8 -3.09E7 -0.7 -0.4835 -0.6919 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A23 mock treatment 5.51519327E8 4580000.0 0.07 5.56881056E8 -3.1E7 -0.7 -0.4457 -0.6319 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base A24 mock treatment 5.56828033E8 9890000.0 0.15 5.62167618E8 -2.58E7 -0.58 -0.3027 -0.5027 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B01 mock treatment 5.56505082E8 9570000.0 0.15 5.80585252E8 -7340000.0 -0.17 -0.0119 -0.0536 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B02 mock treatment 5.70807803E8 2.39E7 0.37 5.86988358E8 -938000.0 -0.02 0.2479 0.6657 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B03 mock treatment 5.49983021E8 3040000.0 0.05 6.19486089E8 3.16E7 0.71 0.5379 0.7525 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B04 mock treatment 5.8411523E8 3.72E7 0.58 6.04280117E8 1.64E7 0.37 0.6708 0.9765 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B05 mock treatment 5.5569196E8 8750000.0 0.14 5.99255719E8 1.13E7 0.26 0.2775 0.9565 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B06 mock treatment 5.87275771E8 4.03E7 0.63 6.00757241E8 1.28E7 0.29 0.6493 0.9383 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B07 mock treatment 5.30040154E8 -1.69E7 -0.26 5.80783803E8 -7140000.0 -0.16 -0.3003 -0.9724 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B08 mock treatment 6.00888067E8 5.39E7 0.84 5.84728357E8 -3200000.0 -0.07 0.5431 0.6439 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B09 mock treatment 5.70347356E8 2.34E7 0.36 5.8042932E8 -7500000.0 -0.17 0.138 0.3433 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B10 mock treatment 5.81614981E8 3.47E7 0.54 6.02870452E8 1.49E7 0.34 0.6207 0.9744 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B11 mock treatment 5.58344446E8 1.14E7 0.18 5.93650023E8 5720000.0 0.13 0.2171 0.9879 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B12 mock treatment 5.74125732E8 2.72E7 0.42 5.77546574E8 -1.04E7 -0.23 0.1336 0.2759 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B13 mock treatment 5.67482825E8 2.05E7 0.32 5.89038421E8 1110000.0 0.03 0.244 0.7603 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B14 mock treatment 5.55631172E8 8690000.0 0.14 5.64839807E8 -2.31E7 -0.52 -0.2732 -0.5068 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B15 mock treatment 5.69012238E8 2.21E7 0.34 5.89003646E8 1080000.0 0.02 0.2603 0.7553 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B16 mock treatment 5.82388986E8 3.55E7 0.55 5.71290104E8 -1.66E7 -0.38 0.1246 0.1865 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B17 mock treatment 5.60391042E8 1.35E7 0.21 5.62891517E8 -2.5E7 -0.57 -0.2519 -0.4175 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B18 mock treatment 5.61590683E8 1.47E7 0.23 5.80530555E8 -7400000.0 -0.17 0.0432 0.1527 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B19 mock treatment 5.42699355E8 -4240000.0 -0.07 5.61971982E8 -2.6E7 -0.59 -0.4615 -0.7818 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B20 mock treatment 5.54362345E8 7420000.0 0.12 5.76610192E8 -1.13E7 -0.26 -0.0991 -0.353 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B21 mock treatment 5.71043544E8 2.41E7 0.38 5.51453403E8 -3.65E7 -0.82 -0.3174 -0.3504 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B22 mock treatment 5.65279022E8 1.83E7 0.29 5.70716954E8 -1.72E7 -0.39 -0.073 -0.1513 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B23 mock treatment 5.5893421E8 1.2E7 0.19 5.66086687E8 -2.18E7 -0.49 -0.2169 -0.411 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base B24 mock treatment 5.47163284E8 225000.0 0.0 5.58897389E8 -2.9E7 -0.66 -0.4614 -0.7033 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C01 mock treatment 6.1792803E7 -4.85E8 -7.56 5.84971434E8 -2950000.0 -0.07 -5.3906 -0.7133 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C02 mock treatment 1.2789923E8 -4.19E8 -6.53 5.77544033E8 -1.04E7 -0.23 -4.7812 -0.7321 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C03 mock treatment 2.30186494E8 -3.17E8 -4.93 5.83257567E8 -4670000.0 -0.11 -3.5633 -0.7221 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C04 mock treatment 3.2296106E8 -2.24E8 -3.49 6.10595838E8 2.27E7 0.51 -2.1046 -0.5969 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C05 mock treatment 3.61589092E8 -1.85E8 -2.89 6.09562055E8 2.16E7 0.49 -1.6957 -0.5791 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C06 mock treatment 3.91801796E8 -1.55E8 -2.42 5.99077484E8 1.12E7 0.25 -1.5305 -0.6299 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C07 mock treatment 4.07645817E8 -1.39E8 -2.17 6.15005084E8 2.71E7 0.61 -1.1014 -0.4886 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C08 mock treatment 4.45457186E8 -1.01E8 -1.58 6.0370218E8 1.58E7 0.36 -0.8656 -0.5342 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C09 mock treatment 4.74033883E8 -7.29E7 -1.14 5.7993445E8 -7990000.0 -0.18 -0.9307 -0.8094 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C10 mock treatment 5.51004604E8 4070000.0 0.06 5.7980473E8 -8120000.0 -0.18 -0.085 -0.4378 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C11 mock treatment 5.47903204E8 965000.0 0.02 5.97169369E8 9240000.0 0.21 0.1583 0.756 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C12 mock treatment 5.56248033E8 9310000.0 0.15 5.71796945E8 -1.61E7 -0.36 -0.1552 -0.3957 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C13 mock treatment 5.32971633E8 -1.4E7 -0.22 5.90474559E8 2550000.0 0.06 -0.1131 -0.5026 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C14 mock treatment 5.57679895E8 1.07E7 0.17 5.83794843E8 -4130000.0 -0.09 0.0523 0.2729 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C15 mock treatment 5.71372767E8 2.44E7 0.38 5.80083415E8 -7840000.0 -0.18 0.1438 0.3425 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C16 mock treatment 5.69130126E8 2.22E7 0.35 5.9179611E8 3870000.0 0.09 0.3063 0.859 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C17 mock treatment 5.61537673E8 1.46E7 0.23 5.78231693E8 -9690000.0 -0.22 0.0059 0.0186 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C18 mock treatment 5.66652611E8 1.97E7 0.31 5.99956606E8 1.2E7 0.27 0.4094 0.9982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C19 mock treatment 5.73099604E8 2.62E7 0.41 5.94188915E8 6260000.0 0.14 0.3882 0.9 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C20 mock treatment 5.63411353E8 1.65E7 0.26 5.80432166E8 -7490000.0 -0.17 0.0617 0.2006 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C21 mock treatment 5.8440617E8 3.75E7 0.58 5.88856348E8 930000.0 0.02 0.4275 0.7321 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C22 mock treatment 5.69056471E8 2.21E7 0.34 5.96299402E8 8370000.0 0.19 0.3774 0.9602 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C23 mock treatment 5.54671021E8 7730000.0 0.12 5.7781785E8 -1.01E7 -0.23 -0.0764 -0.2957 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base C24 mock treatment 5.55653043E8 8710000.0 0.14 5.91992548E8 4070000.0 0.09 0.161 0.982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D01 mock treatment 5.52246826E8 5310000.0 0.08 6.2223408E8 3.43E7 0.78 0.6067 0.7781 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D02 mock treatment 5.93876269E8 4.69E7 0.73 5.89275269E8 1350000.0 0.03 0.5385 0.736 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D03 mock treatment 5.66359627E8 1.94E7 0.3 5.74163463E8 -1.38E7 -0.31 -0.006 -0.0139 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D04 mock treatment 5.55956799E8 9020000.0 0.14 6.22139781E8 3.42E7 0.77 0.6461 0.8221 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D05 mock treatment 5.72569006E8 2.56E7 0.4 6.2952161E8 4.16E7 0.94 0.947 0.9272 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D06 mock treatment 5.84359912E8 3.74E7 0.58 5.99538668E8 1.16E7 0.26 0.5977 0.9351 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D07 mock treatment 5.82766583E8 3.58E7 0.56 6.0382945E8 1.59E7 0.36 0.6488 0.9774 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D08 mock treatment 5.85843773E8 3.89E7 0.61 6.29825094E8 4.19E7 0.95 1.0981 0.9767 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D09 mock treatment 5.76388386E8 2.94E7 0.46 6.08572293E8 2.06E7 0.47 0.6543 1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D10 mock treatment 5.97277548E8 5.03E7 0.78 6.11938716E8 2.4E7 0.54 0.9382 0.9838 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D11 mock treatment 5.53641149E8 6700000.0 0.1 5.94470648E8 6540000.0 0.15 0.1784 0.9855 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D12 mock treatment 5.65439307E8 1.85E7 0.29 5.78118031E8 -9810000.0 -0.22 0.047 0.1293 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D13 mock treatment 5.7470607E8 2.78E7 0.43 5.59109202E8 -2.88E7 -0.65 -0.1547 -0.1979 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D14 mock treatment 5.62979427E8 1.6E7 0.25 5.85924442E8 -2000000.0 -0.05 0.1447 0.5698 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D15 mock treatment 5.98204804E8 5.13E7 0.8 5.87451873E8 -474000.0 -0.01 0.5571 0.6976 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D16 mock treatment 5.56152201E8 9210000.0 0.14 6.04496092E8 1.66E7 0.37 0.3663 0.9133 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D17 mock treatment 5.59899039E8 1.3E7 0.2 5.81200418E8 -6730000.0 -0.15 0.0353 0.1395 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D18 mock treatment 5.52561297E8 5620000.0 0.09 5.9676793E8 8840000.0 0.2 0.2032 0.9315 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D19 mock treatment 5.61792863E8 1.49E7 0.23 5.89117135E8 1190000.0 0.03 0.1826 0.7841 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D20 mock treatment 5.56469274E8 9530000.0 0.15 5.9934963E8 1.14E7 0.26 0.2875 0.9655 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D21 mock treatment 5.72045197E8 2.51E7 0.39 5.78476201E8 -9450000.0 -0.21 0.1255 0.2817 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D22 mock treatment 5.77714412E8 3.08E7 0.48 6.03245286E8 1.53E7 0.35 0.5838 0.9872 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D23 mock treatment 5.46577274E8 -361000.0 -0.01 5.84680258E8 -3250000.0 -0.07 -0.0559 -0.7591 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base D24 mock treatment 5.67568228E8 2.06E7 0.32 5.75520159E8 -1.24E7 -0.28 0.029 0.0679 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E01 mock treatment 7.7940604E7 -4.69E8 -7.31 5.61300106E8 -2.66E7 -0.6 -5.591 -0.7628 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E02 mock treatment 1.5041495E8 -3.97E8 -6.18 5.47163469E8 -4.08E7 -0.92 -5.0187 -0.8037 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E03 mock treatment 2.47973954E8 -2.99E8 -4.66 5.59114182E8 -2.88E7 -0.65 -3.7532 -0.7982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E04 mock treatment 2.7784719E8 -2.69E8 -4.19 6.05193715E8 1.73E7 0.39 -2.6878 -0.6385 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E05 mock treatment 3.09821281E8 -2.37E8 -3.69 5.82923686E8 -5000000.0 -0.11 -2.6915 -0.7284 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E06 mock treatment 3.15180298E8 -2.32E8 -3.61 5.35493376E8 -5.24E7 -1.18 -3.3905 -0.8924 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E07 mock treatment 3.38372753E8 -2.09E8 -3.25 5.77387213E8 -1.05E7 -0.24 -2.4655 -0.7569 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E08 mock treatment 3.92198813E8 -1.55E8 -2.41 5.91415802E8 3490000.0 0.08 -1.6485 -0.6836 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E09 mock treatment 4.13571958E8 -1.33E8 -2.08 5.86595905E8 -1330000.0 -0.03 -1.4901 -0.7173 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E10 mock treatment 4.61912155E8 -8.5E7 -1.32 5.74745115E8 -1.32E7 -0.3 -1.1471 -0.845 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E11 mock treatment 5.00901027E8 -4.6E7 -0.72 5.94718264E8 6790000.0 0.15 -0.3985 -0.5434 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E12 mock treatment 5.07998332E8 -3.89E7 -0.61 5.78711299E8 -9210000.0 -0.21 -0.5761 -0.8984 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E13 mock treatment 5.16705908E8 -3.02E7 -0.47 5.59634349E8 -2.83E7 -0.64 -0.7851 -0.9887 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E14 mock treatment 5.15208182E8 -3.17E7 -0.49 5.82054825E8 -5870000.0 -0.13 -0.4433 -0.8663 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E15 mock treatment 5.19628202E8 -2.73E7 -0.43 5.7721629E8 -1.07E7 -0.24 -0.4719 -0.9643 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E16 mock treatment 5.30802882E8 -1.61E7 -0.25 5.79451412E8 -8470000.0 -0.19 -0.3131 -0.991 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E17 mock treatment 5.11183417E8 -3.58E7 -0.56 5.70662629E8 -1.73E7 -0.39 -0.6697 -0.9848 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E18 mock treatment 5.25829291E8 -2.11E7 -0.33 5.72672612E8 -1.53E7 -0.34 -0.4763 -0.9997 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E19 mock treatment 5.36855805E8 -1.01E7 -0.16 5.46115657E8 -4.18E7 -0.94 -0.7792 -0.8135 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E20 mock treatment 5.4132126E8 -5620000.0 -0.09 5.81741935E8 -6180000.0 -0.14 -0.1607 -0.9746 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E21 mock treatment 5.21985411E8 -2.5E7 -0.39 5.61081898E8 -2.68E7 -0.61 -0.7038 -0.9768 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E22 mock treatment 5.35461789E8 -1.15E7 -0.18 5.6112363E8 -2.68E7 -0.61 -0.5547 -0.8783 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E23 mock treatment 5.3101766E8 -1.59E7 -0.25 5.56848722E8 -3.11E7 -0.7 -0.672 -0.9022 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base E24 mock treatment 5.35990581E8 -1.09E7 -0.17 5.68383907E8 -1.95E7 -0.44 -0.4329 -0.9143 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F01 mock treatment 5.51292035E8 4350000.0 0.07 5.87282171E8 -644000.0 -0.01 0.0377 0.543 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F02 mock treatment 5.59703024E8 1.28E7 0.2 5.78741358E8 -9180000.0 -0.21 -0.0062 -0.0215 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F03 mock treatment 5.45539807E8 -1400000.0 -0.02 5.92174759E8 4250000.0 0.1 0.0525 0.5331 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F04 mock treatment 5.52688811E8 5750000.0 0.09 5.98464595E8 1.05E7 0.24 0.2317 0.9108 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F05 mock treatment 5.60872456E8 1.39E7 0.22 6.18507604E8 3.06E7 0.69 0.6422 0.8865 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F06 mock treatment 5.35543237E8 -1.14E7 -0.18 6.00383005E8 1.25E7 0.28 0.0736 0.221 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F07 mock treatment 5.7273818E8 2.58E7 0.4 6.0104531E8 1.31E7 0.3 0.4938 0.9888 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F08 mock treatment 5.79951309E8 3.3E7 0.51 6.3186799E8 4.39E7 0.99 1.0658 0.9531 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F09 mock treatment 5.90171566E8 4.32E7 0.67 5.91028149E8 3100000.0 0.07 0.5257 0.7765 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F10 mock treatment 5.85415961E8 3.85E7 0.6 5.75862325E8 -1.21E7 -0.27 0.231 0.3508 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F11 mock treatment 5.43649929E8 -3290000.0 -0.05 6.17097988E8 2.92E7 0.66 0.43 0.6502 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F12 mock treatment 5.60608887E8 1.37E7 0.21 5.67163697E8 -2.08E7 -0.47 -0.1812 -0.3517 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F13 mock treatment 5.2704326E8 -1.99E7 -0.31 5.91494285E8 3570000.0 0.08 -0.1621 -0.5062 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F14 mock treatment 5.5564034E8 8700000.0 0.14 5.97828821E8 9900000.0 0.22 0.2541 0.9711 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F15 mock treatment 5.62357968E8 1.54E7 0.24 5.86727192E8 -1200000.0 -0.03 0.1507 0.6234 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F16 mock treatment 5.55150006E8 8210000.0 0.13 5.93089145E8 5160000.0 0.12 0.1729 0.9989 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F17 mock treatment 5.26836513E8 -2.01E7 -0.31 5.69242944E8 -1.87E7 -0.42 -0.52 -0.9892 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F18 mock treatment 5.65998201E8 1.91E7 0.3 5.76181987E8 -1.17E7 -0.27 0.0222 0.0559 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F19 mock treatment 5.48720278E8 1780000.0 0.03 5.76019043E8 -1.19E7 -0.27 -0.1707 -0.6308 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F20 mock treatment 5.62709753E8 1.58E7 0.25 5.92657371E8 4730000.0 0.11 0.2493 0.9306 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F21 mock treatment 5.45241439E8 -1700000.0 -0.03 5.71125842E8 -1.68E7 -0.38 -0.2872 -0.7545 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F22 mock treatment 5.50063296E8 3120000.0 0.05 5.60587234E8 -2.73E7 -0.62 -0.4025 -0.6494 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F23 mock treatment 5.48267223E8 1330000.0 0.02 5.62430431E8 -2.55E7 -0.58 -0.3928 -0.6813 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base F24 mock treatment 5.34673916E8 -1.23E7 -0.19 5.60952993E8 -2.7E7 -0.61 -0.5661 -0.8862 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G01 mock treatment 1.59117908E8 -3.88E8 -6.04 5.86707046E8 -1220000.0 -0.03 -4.2909 -0.7103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G02 mock treatment 2.43199639E8 -3.04E8 -4.73 5.92027083E8 4100000.0 0.09 -3.2798 -0.6931 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G03 mock treatment 2.98369001E8 -2.49E8 -3.87 5.82332566E8 -5590000.0 -0.13 -2.8271 -0.7298 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G04 mock treatment 3.11301074E8 -2.36E8 -3.67 5.92386551E8 4460000.0 0.1 -2.524 -0.6874 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G05 mock treatment 3.27177243E8 -2.2E8 -3.42 5.79288651E8 -8640000.0 -0.2 -2.5585 -0.7462 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G06 mock treatment 3.35528558E8 -2.11E8 -3.29 5.95590748E8 7660000.0 0.17 -2.206 -0.669 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G07 mock treatment 3.91233467E8 -1.56E8 -2.43 6.00141108E8 1.22E7 0.28 -1.5197 -0.6226 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G08 mock treatment 4.47812329E8 -9.91E7 -1.54 5.84966469E8 -2960000.0 -0.07 -1.1391 -0.737 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G09 mock treatment 4.6491531E8 -8.2E7 -1.28 6.027737E8 1.48E7 0.34 -0.6661 -0.5043 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G10 mock treatment 5.10674865E8 -3.63E7 -0.56 5.61935961E8 -2.6E7 -0.59 -0.8147 -0.9998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G11 mock treatment 4.8999782E8 -5.69E7 -0.89 5.65901688E8 -2.2E7 -0.5 -0.9791 -0.9627 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G12 mock treatment 5.10055146E8 -3.69E7 -0.57 5.84469106E8 -3460000.0 -0.08 -0.4615 -0.7959 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G13 mock treatment 4.7337392E8 -7.36E7 -1.15 5.86452077E8 -1470000.0 -0.03 -0.8338 -0.7274 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G14 mock treatment 5.35950641E8 -1.1E7 -0.17 5.95998108E8 8070000.0 0.18 0.008 0.0319 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G15 mock treatment 5.35131889E8 -1.18E7 -0.18 6.16544403E8 2.86E7 0.65 0.3273 0.4868 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G16 mock treatment 5.4296801E8 -3970000.0 -0.06 6.02429523E8 1.45E7 0.33 0.188 0.5637 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G17 mock treatment 5.50519591E8 3580000.0 0.06 5.90351922E8 2430000.0 0.05 0.0782 1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G18 mock treatment 5.72288964E8 2.54E7 0.39 5.92087441E8 4160000.0 0.09 0.3457 0.8517 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G19 mock treatment 5.37912574E8 -9030000.0 -0.14 5.84765119E8 -3160000.0 -0.07 -0.1499 -0.9507 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G20 mock treatment 5.47395277E8 457000.0 0.01 6.05126419E8 1.72E7 0.39 0.2799 0.7199 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G21 mock treatment 5.44054334E8 -2880000.0 -0.04 5.87128523E8 -798000.0 -0.02 -0.0445 -0.9196 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G22 mock treatment 5.84113065E8 3.72E7 0.58 5.94291497E8 6370000.0 0.14 0.5112 0.8567 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G23 mock treatment 5.50961531E8 4020000.0 0.06 5.84925133E8 -3000000.0 -0.07 -0.0037 -0.0395 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base G24 mock treatment 5.52621971E8 5680000.0 0.09 5.73980106E8 -1.39E7 -0.32 -0.1603 -0.4896 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H01 mock treatment 6.08029045E8 6.11E7 0.95 6.35803956E8 4.79E7 1.08 1.438 0.9979 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H02 mock treatment 5.56849719E8 9910000.0 0.15 6.03452563E8 1.55E7 0.35 0.3573 0.932 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H03 mock treatment 5.83028334E8 3.61E7 0.56 6.34727837E8 4.68E7 1.06 1.1454 0.9562 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H04 mock treatment 5.73422474E8 2.65E7 0.41 6.34582363E8 4.67E7 1.05 1.0373 0.9161 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H05 mock treatment 5.58850203E8 1.19E7 0.19 6.11348494E8 2.34E7 0.53 0.5055 0.9012 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H06 mock treatment 5.76535578E8 2.96E7 0.46 6.01646075E8 1.37E7 0.31 0.5452 0.9814 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H07 mock treatment 6.09040448E8 6.21E7 0.97 6.37441888E8 4.95E7 1.12 1.4753 0.9974 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H08 mock treatment 5.91401426E8 4.45E7 0.69 6.32830198E8 4.49E7 1.01 1.2073 0.9826 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H09 mock treatment 5.96787638E8 4.98E7 0.78 6.49350856E8 6.14E7 1.39 1.5306 0.9623 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H10 mock treatment 5.35913794E8 -1.1E7 -0.17 6.16418029E8 2.85E7 0.64 0.3339 0.501 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H11 mock treatment 5.77917759E8 3.1E7 0.48 6.0752733E8 1.96E7 0.44 0.6544 0.9991 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H12 mock treatment 5.90507864E8 4.36E7 0.68 5.92450176E8 4520000.0 0.1 0.5522 0.8046 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H13 mock treatment 5.5967255E8 1.27E7 0.2 6.18744669E8 3.08E7 0.7 0.6328 0.8737 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H14 mock treatment 5.84058823E8 3.71E7 0.58 6.28717281E8 4.08E7 0.92 1.0607 0.9747 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H15 mock treatment 5.93896977E8 4.7E7 0.73 6.09843453E8 2.19E7 0.5 0.8674 0.982 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H16 mock treatment 5.78630594E8 3.17E7 0.49 6.16825375E8 2.89E7 0.65 0.8109 0.9905 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H17 mock treatment 5.95669006E8 4.87E7 0.76 6.32320788E8 4.44E7 1.0 1.2462 0.9905 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H18 mock treatment 5.73426521E8 2.65E7 0.41 6.16898659E8 2.9E7 0.65 0.7547 0.9752 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H19 mock treatment 5.71260596E8 2.43E7 0.38 6.28326302E8 4.04E7 0.91 0.9135 0.9241 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H20 mock treatment 5.83754781E8 3.68E7 0.57 5.89395558E8 1470000.0 0.03 0.429 0.7468 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H21 mock treatment 5.64107765E8 1.72E7 0.27 6.14620166E8 2.67E7 0.6 0.6157 0.933 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H22 mock treatment 5.71769418E8 2.48E7 0.39 5.99397838E8 1.15E7 0.26 0.4568 0.9811 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H23 mock treatment 5.5914345E8 1.22E7 0.19 6.04202107E8 1.63E7 0.37 0.3945 0.9528 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base H24 mock treatment 5.56526771E8 9590000.0 0.15 5.82891862E8 -5030000.0 -0.11 0.0252 0.134 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I01 mock treatment 1.76643508E8 -3.7E8 -5.77 5.9129722E8 3370000.0 0.08 -4.0245 -0.6977 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I02 mock treatment 2.59763247E8 -2.87E8 -4.47 5.92169458E8 4240000.0 0.1 -3.0951 -0.6918 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I03 mock treatment 3.15564485E8 -2.31E8 -3.6 5.94381713E8 6460000.0 0.15 -2.4452 -0.6779 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I04 mock treatment 3.33780392E8 -2.13E8 -3.32 5.82899261E8 -5030000.0 -0.11 -2.428 -0.7309 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I05 mock treatment 3.45258662E8 -2.02E8 -3.14 5.76736284E8 -1.12E7 -0.25 -2.4001 -0.7616 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I06 mock treatment 3.9058544E8 -1.56E8 -2.44 5.86689227E8 -1240000.0 -0.03 -1.7418 -0.7152 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I07 mock treatment 4.20752671E8 -1.26E8 -1.97 5.8927886E8 1350000.0 0.03 -1.3682 -0.696 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I08 mock treatment 4.59755077E8 -8.72E7 -1.36 6.15745155E8 2.78E7 0.63 -0.5157 -0.3446 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I09 mock treatment 5.00263661E8 -4.67E7 -0.73 5.81453807E8 -6470000.0 -0.15 -0.6175 -0.8327 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I10 mock treatment 4.93583463E8 -5.34E7 -0.83 5.86305811E8 -1620000.0 -0.04 -0.6135 -0.7376 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I11 mock treatment 5.17352753E8 -2.96E7 -0.46 5.85067965E8 -2860000.0 -0.06 -0.3715 -0.7984 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I12 mock treatment 5.21598579E8 -2.53E7 -0.39 5.94692691E8 6770000.0 0.15 -0.171 -0.4039 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I13 mock treatment 5.57505031E8 1.06E7 0.16 5.51918544E8 -3.6E7 -0.81 -0.459 -0.5529 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I14 mock treatment 5.61783914E8 1.48E7 0.23 5.82078169E8 -5850000.0 -0.13 0.07 0.263 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I15 mock treatment 5.5446323E8 7520000.0 0.12 5.79024391E8 -8900000.0 -0.2 -0.0594 -0.255 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I16 mock treatment 5.64142832E8 1.72E7 0.27 5.83880751E8 -4050000.0 -0.09 0.1248 0.4409 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I17 mock treatment 5.64582956E8 1.76E7 0.27 5.71312905E8 -1.66E7 -0.38 -0.0712 -0.1529 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I18 mock treatment 5.56854219E8 9920000.0 0.15 5.79010717E8 -8920000.0 -0.2 -0.0333 -0.131 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I19 mock treatment 5.47047057E8 109000.0 0.0 5.72111048E8 -1.58E7 -0.36 -0.2515 -0.7038 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I20 mock treatment 5.69110287E8 2.22E7 0.35 5.68945669E8 -1.9E7 -0.43 -0.0591 -0.1074 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I21 mock treatment 5.3593023E8 -1.1E7 -0.17 5.76616096E8 -1.13E7 -0.26 -0.302 -0.9811 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I22 mock treatment 5.24957743E8 -2.2E7 -0.34 5.88416025E8 490000.0 0.01 -0.2343 -0.6839 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I23 mock treatment 5.38592395E8 -8350000.0 -0.13 5.68828316E8 -1.91E7 -0.43 -0.3971 -0.881 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base I24 mock treatment 5.29132473E8 -1.78E7 -0.28 5.66298276E8 -2.16E7 -0.49 -0.5417 -0.964 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J01 mock treatment 5.30068837E8 -1.69E7 -0.26 6.02819633E8 1.49E7 0.34 0.0522 0.1223 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J02 mock treatment 5.55845297E8 8910000.0 0.14 6.32217299E8 4.43E7 1.0 0.8059 0.7975 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J03 mock treatment 5.58620293E8 1.17E7 0.18 6.11905677E8 2.4E7 0.54 0.5119 0.8954 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J04 mock treatment 5.57672274E8 1.07E7 0.17 5.8980803E8 1880000.0 0.04 0.1483 0.8596 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J05 mock treatment 5.62263496E8 1.53E7 0.24 6.26078768E8 3.82E7 0.86 0.7785 0.8701 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J06 mock treatment 5.26482745E8 -2.05E7 -0.32 5.72351455E8 -1.56E7 -0.35 -0.4742 -0.9988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J07 mock treatment 5.26419061E8 -2.05E7 -0.32 6.22527253E8 3.46E7 0.78 0.3269 0.387 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J08 mock treatment 5.81290873E8 3.44E7 0.54 6.10478554E8 2.26E7 0.51 0.7388 0.9997 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J09 mock treatment 5.52474036E8 5540000.0 0.09 5.93332423E8 5410000.0 0.12 0.1474 0.9854 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J10 mock treatment 5.58909497E8 1.2E7 0.19 5.84354436E8 -3570000.0 -0.08 0.0748 0.368 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J11 mock treatment 5.55934701E8 9000000.0 0.14 5.83066236E8 -4860000.0 -0.11 0.0214 0.1203 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J12 mock treatment 5.61277421E8 1.43E7 0.22 5.72705472E8 -1.52E7 -0.34 -0.0853 -0.208 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J13 mock treatment 5.58974055E8 1.2E7 0.19 5.74258598E8 -1.37E7 -0.31 -0.0859 -0.2376 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J14 mock treatment 5.69578044E8 2.26E7 0.35 5.87775615E8 -151000.0 0.0 0.2469 0.7002 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J15 mock treatment 5.82873871E8 3.59E7 0.56 5.81780005E8 -6150000.0 -0.14 0.2976 0.516 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J16 mock treatment 5.81666323E8 3.47E7 0.54 5.91886149E8 3960000.0 0.09 0.4458 0.813 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J17 mock treatment 5.5552373E8 8590000.0 0.13 5.7982056E8 -8110000.0 -0.18 -0.035 -0.1542 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J18 mock treatment 5.50650464E8 3710000.0 0.06 5.70989582E8 -1.69E7 -0.38 -0.2298 -0.5936 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J19 mock treatment 5.38753775E8 -8180000.0 -0.13 5.73713962E8 -1.42E7 -0.32 -0.3173 -0.9181 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J20 mock treatment 5.32932751E8 -1.4E7 -0.22 5.89720656E8 1790000.0 0.04 -0.1256 -0.566 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J21 mock treatment 5.60486806E8 1.35E7 0.21 5.79499476E8 -8430000.0 -0.19 0.0146 0.0512 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J22 mock treatment 5.1970224E8 -2.72E7 -0.42 5.97609543E8 9680000.0 0.22 -0.1452 -0.3042 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J23 mock treatment 5.46017367E8 -921000.0 -0.01 5.84532601E8 -3390000.0 -0.08 -0.0644 -0.8251 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base J24 mock treatment 5.29514885E8 -1.74E7 -0.27 5.66283906E8 -2.16E7 -0.49 -0.5378 -0.9614 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K01 mock treatment 2.39489288E8 -3.07E8 -4.79 5.54020141E8 -3.39E7 -0.77 -3.9281 -0.81 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K02 mock treatment 3.34379259E8 -2.13E8 -3.31 5.63859157E8 -2.41E7 -0.54 -2.7257 -0.8124 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K03 mock treatment 3.95142066E8 -1.52E8 -2.36 5.73388216E8 -1.45E7 -0.33 -1.9042 -0.7977 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K04 mock treatment 4.01748212E8 -1.45E8 -2.26 5.50396291E8 -3.75E7 -0.85 -2.1989 -0.9104 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K05 mock treatment 4.20855516E8 -1.26E8 -1.96 5.73364401E8 -1.46E7 -0.33 -1.6214 -0.8142 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K06 mock treatment 4.48201305E8 -9.87E7 -1.54 5.92726405E8 4800000.0 0.11 -1.0108 -0.6556 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K07 mock treatment 4.56610946E8 -9.03E7 -1.41 5.83400972E8 -4530000.0 -0.1 -1.0672 -0.7565 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K08 mock treatment 5.24627287E8 -2.23E7 -0.35 5.97021687E8 9100000.0 0.21 -0.1004 -0.2486 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K09 mock treatment 5.45990762E8 -948000.0 -0.01 5.72959495E8 -1.5E7 -0.34 -0.2496 -0.7373 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K10 mock treatment 5.65158244E8 1.82E7 0.28 5.72632859E8 -1.53E7 -0.35 -0.0437 -0.0978 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K11 mock treatment 5.77077704E8 3.01E7 0.47 5.74489677E8 -1.34E7 -0.3 0.1172 0.2097 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K12 mock treatment 5.46866448E8 -72100.0 0.0 5.82844578E8 -5080000.0 -0.11 -0.082 -0.714 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K13 mock treatment 5.64056277E8 1.71E7 0.27 6.05821541E8 1.79E7 0.4 0.4745 0.9796 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K14 mock treatment 5.80843698E8 3.39E7 0.53 5.8639928E8 -1530000.0 -0.03 0.349 0.6595 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K15 mock treatment 5.81924896E8 3.5E7 0.54 5.82484702E8 -5440000.0 -0.12 0.2984 0.5341 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K16 mock treatment 5.61610675E8 1.47E7 0.23 5.88617321E8 691000.0 0.02 0.1726 0.7537 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K17 mock treatment 5.64483501E8 1.75E7 0.27 5.78989313E8 -8940000.0 -0.2 0.0504 0.1484 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K18 mock treatment 5.76136933E8 2.92E7 0.45 5.71614893E8 -1.63E7 -0.37 0.0609 0.1041 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K19 mock treatment 5.24687229E8 -2.23E7 -0.35 5.62125568E8 -2.58E7 -0.58 -0.6574 -0.9691 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K20 mock treatment 5.78663336E8 3.17E7 0.49 5.79499666E8 -8430000.0 -0.19 0.2148 0.4055 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K21 mock treatment 5.58245436E8 1.13E7 0.18 5.74293691E8 -1.36E7 -0.31 -0.0933 -0.263 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K22 mock treatment 5.41576491E8 -5360000.0 -0.08 5.79923469E8 -8000000.0 -0.18 -0.1869 -0.9384 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K23 mock treatment 5.27824752E8 -1.91E7 -0.3 5.67452004E8 -2.05E7 -0.46 -0.5377 -0.9773 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base K24 mock treatment 5.35694731E8 -1.12E7 -0.18 5.65416645E8 -2.25E7 -0.51 -0.4836 -0.8988 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L01 mock treatment 5.29601668E8 -1.73E7 -0.27 5.86490237E8 -1440000.0 -0.03 -0.2139 -0.7864 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L02 mock treatment 5.5955559E8 1.26E7 0.2 5.98059155E8 1.01E7 0.23 0.3009 0.9971 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L03 mock treatment 5.88513993E8 4.16E7 0.65 6.05414742E8 1.75E7 0.4 0.7374 0.9719 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L04 mock treatment 5.90955043E8 4.4E7 0.69 5.93878856E8 5950000.0 0.13 0.5799 0.83 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L05 mock treatment 5.83831096E8 3.69E7 0.57 6.15798691E8 2.79E7 0.63 0.8518 0.9989 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L06 mock treatment 5.98282635E8 5.13E7 0.8 6.11314832E8 2.34E7 0.53 0.9393 0.9798 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L07 mock treatment 5.58661969E8 1.17E7 0.18 6.19567438E8 3.16E7 0.72 0.6348 0.8601 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L08 mock treatment 5.84349471E8 3.74E7 0.58 6.03017866E8 1.51E7 0.34 0.6532 0.9675 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L09 mock treatment 5.80071259E8 3.31E7 0.52 5.89335416E8 1410000.0 0.03 0.3874 0.7493 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L10 mock treatment 5.89544995E8 4.26E7 0.66 6.08514837E8 2.06E7 0.47 0.7983 0.9849 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L11 mock treatment 5.73435981E8 2.65E7 0.41 6.01464492E8 1.35E7 0.31 0.5082 0.9891 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L12 mock treatment 5.89365619E8 4.24E7 0.66 5.60174947E8 -2.78E7 -0.63 0.0238 0.0261 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L13 mock treatment 5.46996229E8 57700.0 0.0 5.96808442E8 8880000.0 0.2 0.1426 0.7103 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L14 mock treatment 5.83061773E8 3.61E7 0.56 6.09777098E8 2.19E7 0.49 0.747 0.9979 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L15 mock treatment 5.88494045E8 4.16E7 0.65 5.91879802E8 3950000.0 0.09 0.5209 0.7972 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L16 mock treatment 5.54224486E8 7290000.0 0.11 6.05426508E8 1.75E7 0.4 0.3599 0.8747 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L17 mock treatment 5.50661715E8 3720000.0 0.06 5.89658839E8 1730000.0 0.04 0.0687 0.9817 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L18 mock treatment 5.53745685E8 6810000.0 0.11 5.78755095E8 -9170000.0 -0.21 -0.0716 -0.3075 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L19 mock treatment 5.5240238E8 5460000.0 0.09 5.86714922E8 -1210000.0 -0.03 0.0408 0.4566 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L20 mock treatment 5.81783962E8 3.48E7 0.54 5.74395574E8 -1.35E7 -0.31 0.1676 0.269 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L21 mock treatment 5.89950726E8 4.3E7 0.67 5.75644293E8 -1.23E7 -0.28 0.2775 0.3826 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L22 mock treatment 5.46476541E8 -462000.0 -0.01 5.93243274E8 5320000.0 0.12 0.0799 0.6636 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L23 mock treatment 5.46118937E8 -820000.0 -0.01 5.83964108E8 -3960000.0 -0.09 -0.0723 -0.7998 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base L24 mock treatment 5.33531926E8 -1.34E7 -0.21 5.74745465E8 -1.32E7 -0.3 -0.3583 -0.9849 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M01 mock treatment 2.13622836E8 -3.33E8 -5.19 5.88400905E8 475000.0 0.01 -3.6635 -0.7056 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M02 mock treatment 2.92724843E8 -2.54E8 -3.96 5.88864049E8 938000.0 0.02 -2.7849 -0.7033 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M03 mock treatment 3.39046303E8 -2.08E8 -3.24 5.90171166E8 2240000.0 0.05 -2.2538 -0.6959 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M04 mock treatment 3.48079476E8 -1.99E8 -3.1 5.85658795E8 -2270000.0 -0.05 -2.2264 -0.7187 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M05 mock treatment 3.59858574E8 -1.87E8 -2.91 5.67933987E8 -2.0E7 -0.45 -2.38 -0.8071 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M06 mock treatment 4.05339077E8 -1.42E8 -2.21 5.78921598E8 -9000000.0 -0.2 -1.7035 -0.7691 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M07 mock treatment 4.48812826E8 -9.81E7 -1.53 6.1107114E8 2.31E7 0.52 -0.7109 -0.4401 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M08 mock treatment 4.87341899E8 -5.96E7 -0.93 5.75720494E8 -1.22E7 -0.28 -0.8514 -0.8792 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M09 mock treatment 5.15620176E8 -3.13E7 -0.49 5.83304288E8 -4620000.0 -0.1 -0.4188 -0.8395 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M10 mock treatment 5.51799003E8 4860000.0 0.08 6.00871685E8 1.29E7 0.29 0.2604 0.8617 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M11 mock treatment 5.42461393E8 -4480000.0 -0.07 5.97996853E8 1.01E7 0.23 0.1116 0.4689 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M12 mock treatment 5.47175063E8 237000.0 0.0 5.75935374E8 -1.2E7 -0.27 -0.189 -0.6974 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M13 mock treatment 5.39661984E8 -7280000.0 -0.11 5.70316142E8 -1.76E7 -0.4 -0.3616 -0.8737 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M14 mock treatment 5.36906142E8 -1.0E7 -0.16 5.76678736E8 -1.12E7 -0.25 -0.2902 -0.9727 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M15 mock treatment 5.59392228E8 1.25E7 0.19 5.98674776E8 1.07E7 0.24 0.3089 0.9938 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M16 mock treatment 5.53073481E8 6130000.0 0.1 5.72778305E8 -1.51E7 -0.34 -0.1745 -0.491 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M17 mock treatment 5.47094369E8 156000.0 0.0 5.69475491E8 -1.85E7 -0.42 -0.2931 -0.703 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M18 mock treatment 5.52126185E8 5190000.0 0.08 5.85745737E8 -2180000.0 -0.05 0.0223 0.2355 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M19 mock treatment 5.8366229E8 3.67E7 0.57 5.85320052E8 -2610000.0 -0.06 0.3628 0.631 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M20 mock treatment 5.7787259E8 3.09E7 0.48 5.7810094E8 -9830000.0 -0.22 0.1837 0.3462 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M21 mock treatment 5.67318158E8 2.04E7 0.32 5.68546358E8 -1.94E7 -0.44 -0.0852 -0.1576 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M22 mock treatment 5.62154909E8 1.52E7 0.24 5.80820564E8 -7110000.0 -0.16 0.054 0.1888 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M23 mock treatment 5.36147637E8 -1.08E7 -0.17 5.85595028E8 -2330000.0 -0.05 -0.1561 -0.8862 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base M24 mock treatment 5.33040728E8 -1.39E7 -0.22 5.51153402E8 -3.68E7 -0.83 -0.7407 -0.8625 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N01 mock treatment 5.45276492E8 -1660000.0 -0.03 5.82005502E8 -5920000.0 -0.13 -0.1129 -0.8285 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N02 mock treatment 5.66707183E8 1.98E7 0.31 5.80151608E8 -7770000.0 -0.18 0.0935 0.2637 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N03 mock treatment 6.03519722E8 5.66E7 0.88 6.18286841E8 3.04E7 0.69 1.1084 0.9923 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N04 mock treatment 5.71266282E8 2.43E7 0.38 5.95456847E8 7530000.0 0.17 0.3883 0.9347 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N05 mock treatment 5.87385641E8 4.04E7 0.63 6.19456256E8 3.15E7 0.71 0.9494 0.9981 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N06 mock treatment 5.7665775E8 2.97E7 0.46 6.08222849E8 2.03E7 0.46 0.6517 1.0 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N07 mock treatment 5.86179577E8 3.92E7 0.61 6.25293642E8 3.74E7 0.84 1.0294 0.9874 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N08 mock treatment 5.869933E8 4.01E7 0.62 5.76902925E8 -1.1E7 -0.25 0.265 0.3945 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N09 mock treatment 5.61166562E8 1.42E7 0.22 5.67203771E8 -2.07E7 -0.47 -0.1745 -0.3367 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N10 mock treatment 5.66794905E8 1.99E7 0.31 6.023731E8 1.44E7 0.33 0.4496 0.9996 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N11 mock treatment 5.63409746E8 1.65E7 0.26 5.73199299E8 -1.47E7 -0.33 -0.0539 -0.1283 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N12 mock treatment 5.63392338E8 1.65E7 0.26 6.08137983E8 2.02E7 0.46 0.5042 0.9627 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N13 mock treatment 5.7656502E8 2.96E7 0.46 5.99760363E8 1.18E7 0.27 0.5154 0.9664 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N14 mock treatment 5.78034587E8 3.11E7 0.48 5.8014304E8 -7780000.0 -0.18 0.2181 0.4233 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N15 mock treatment 5.79299062E8 3.24E7 0.5 5.7791385E8 -1.0E7 -0.23 0.1964 0.3555 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N16 mock treatment 5.69757758E8 2.28E7 0.36 5.75840572E8 -1.21E7 -0.27 0.0582 0.1298 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N17 mock treatment 5.7615042E8 2.92E7 0.46 5.84304555E8 -3620000.0 -0.08 0.2639 0.5707 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N18 mock treatment 5.71402651E8 2.45E7 0.38 5.5687826E8 -3.1E7 -0.7 -0.2267 -0.2839 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N19 mock treatment 5.81162308E8 3.42E7 0.53 5.719931E8 -1.59E7 -0.36 0.1223 0.1901 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N20 mock treatment 5.53598645E8 6660000.0 0.1 5.762887E8 -1.16E7 -0.26 -0.1126 -0.3983 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N21 mock treatment 5.63078651E8 1.61E7 0.25 5.92717842E8 4790000.0 0.11 0.2543 0.9292 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N22 mock treatment 5.63553639E8 1.66E7 0.26 5.67928589E8 -2.0E7 -0.45 -0.1366 -0.2622 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N23 mock treatment 5.48787101E8 1850000.0 0.03 6.03307737E8 1.54E7 0.35 0.2662 0.7631 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base N24 mock treatment 5.35592444E8 -1.13E7 -0.18 5.654008E8 -2.25E7 -0.51 -0.4849 -0.8999 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O01 mock treatment 1.9747452E8 -3.49E8 -5.44 5.74801596E8 -1.31E7 -0.3 -4.0587 -0.7445 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O02 mock treatment 2.73995819E8 -2.73E8 -4.25 5.77063241E8 -1.09E7 -0.25 -3.1798 -0.7467 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O03 mock treatment 3.2297501E8 -2.24E8 -3.49 5.61063298E8 -2.69E7 -0.61 -2.896 -0.8179 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O04 mock treatment 3.53005157E8 -1.94E8 -3.02 5.82407642E8 -5520000.0 -0.12 -2.2242 -0.7357 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O05 mock treatment 3.9832277E8 -1.49E8 -2.31 5.6347223E8 -2.45E7 -0.55 -2.0276 -0.852 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O06 mock treatment 4.23510959E8 -1.23E8 -1.92 5.99275806E8 1.13E7 0.26 -1.178 -0.6074 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O07 mock treatment 4.44805959E8 -1.02E8 -1.59 5.94287763E8 6360000.0 0.14 -1.0232 -0.6406 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O08 mock treatment 5.01040028E8 -4.59E7 -0.71 5.78414029E8 -9510000.0 -0.21 -0.6575 -0.8808 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O09 mock treatment 5.20453065E8 -2.65E7 -0.41 5.59075978E8 -2.89E7 -0.65 -0.7528 -0.9756 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O10 mock treatment 5.40922037E8 -6020000.0 -0.09 5.86390747E8 -1540000.0 -0.03 -0.0908 -0.9086 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O11 mock treatment 5.13901643E8 -3.3E7 -0.51 5.81508044E8 -6420000.0 -0.15 -0.4664 -0.8724 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O12 mock treatment 5.4317846E8 -3760000.0 -0.06 5.83840661E8 -4090000.0 -0.09 -0.1067 -0.9759 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O13 mock treatment 5.56283701E8 9350000.0 0.15 5.65605691E8 -2.23E7 -0.5 -0.2538 -0.4833 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O14 mock treatment 5.15516253E8 -3.14E7 -0.49 5.89524978E8 1600000.0 0.04 -0.3205 -0.6531 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O15 mock treatment 5.38168297E8 -8770000.0 -0.14 5.74083299E8 -1.38E7 -0.31 -0.3178 -0.931 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O16 mock treatment 5.37345399E8 -9590000.0 -0.15 5.65424449E8 -2.25E7 -0.51 -0.4653 -0.8778 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O17 mock treatment 5.6349085E8 1.66E7 0.26 5.76953999E8 -1.1E7 -0.25 0.007 0.0195 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O18 mock treatment 5.46294318E8 -644000.0 -0.01 5.66052204E8 -2.19E7 -0.49 -0.3567 -0.7213 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O19 mock treatment 5.65825091E8 1.89E7 0.29 5.6571533E8 -2.22E7 -0.5 -0.1469 -0.2525 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O20 mock treatment 5.74605063E8 2.77E7 0.43 5.68490323E8 -1.94E7 -0.44 -0.0059 -0.0096 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O21 mock treatment 5.49244378E8 2310000.0 0.04 5.85255219E8 -2670000.0 -0.06 -0.0173 -0.2461 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O22 mock treatment 5.53766396E8 6830000.0 0.11 5.84684431E8 -3240000.0 -0.07 0.0234 0.1812 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O23 mock treatment 5.39182445E8 -7760000.0 -0.12 5.69018515E8 -1.89E7 -0.43 -0.3876 -0.8728 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base O24 mock treatment 5.51982058E8 5040000.0 0.08 5.72829952E8 -1.51E7 -0.34 -0.1857 -0.5304 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P01 mock treatment 5.66170862E8 1.92E7 0.3 5.96220479E8 8290000.0 0.19 0.3444 0.9745 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P02 mock treatment 5.51938364E8 5000000.0 0.08 5.9099217E8 3070000.0 0.07 0.1041 0.9983 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P03 mock treatment 5.63065631E8 1.61E7 0.25 6.13591205E8 2.57E7 0.58 0.5878 0.9299 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P04 mock treatment 5.63191153E8 1.63E7 0.25 6.12196841E8 2.43E7 0.55 0.5669 0.9383 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P05 mock treatment 5.69191572E8 2.23E7 0.35 6.21302806E8 3.34E7 0.75 0.7785 0.9378 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P06 mock treatment 5.68782655E8 2.18E7 0.34 6.16967994E8 2.9E7 0.66 0.7047 0.9532 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P07 mock treatment 5.83116081E8 3.62E7 0.56 5.9390268E8 5980000.0 0.14 0.494 0.8525 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P08 mock treatment 5.79590607E8 3.27E7 0.51 5.99973962E8 1.2E7 0.27 0.5522 0.9571 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P09 mock treatment 5.57111133E8 1.02E7 0.16 6.32451487E8 4.45E7 1.01 0.8236 0.8085 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P10 mock treatment 5.65912752E8 1.9E7 0.3 5.90270115E8 2340000.0 0.05 0.2464 0.8208 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P11 mock treatment 5.96350632E8 4.94E7 0.77 6.08747535E8 2.08E7 0.47 0.877 0.9721 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P12 mock treatment 5.6220939E8 1.53E7 0.24 6.23171853E8 3.52E7 0.8 0.7314 0.8799 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P13 mock treatment 5.68822566E8 2.19E7 0.34 5.9777845E8 9850000.0 0.22 0.3985 0.9787 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P14 mock treatment 5.70975178E8 2.4E7 0.37 6.07628902E8 1.97E7 0.45 0.5796 0.9963 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P15 mock treatment 5.79436779E8 3.25E7 0.51 6.17954693E8 3.0E7 0.68 0.8378 0.9896 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P16 mock treatment 5.7072605E8 2.38E7 0.37 6.13596128E8 2.57E7 0.58 0.6722 0.9765 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P17 mock treatment 5.69660962E8 2.27E7 0.35 5.94179143E8 6250000.0 0.14 0.3502 0.9189 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P18 mock treatment 5.77579876E8 3.06E7 0.48 5.99257366E8 1.13E7 0.26 0.5186 0.9574 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P19 mock treatment 5.48012043E8 1070000.0 0.02 6.10729308E8 2.28E7 0.52 0.3762 0.7297 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P20 mock treatment 5.58716092E8 1.18E7 0.18 6.01048574E8 1.31E7 0.3 0.3394 0.9733 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P21 mock treatment 5.66316743E8 1.94E7 0.3 5.96215565E8 8290000.0 0.19 0.3459 0.9737 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P22 mock treatment 5.72220069E8 2.53E7 0.39 5.97427465E8 9500000.0 0.21 0.4303 0.9593 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P23 mock treatment 5.64156197E8 1.72E7 0.27 5.80027111E8 -7900000.0 -0.18 0.0634 0.1968 1071.0003 FluorDeLys(1071.0003) Sir2Modulation 1071.0003.Base P24 mock treatment 5.75625265E8 2.87E7 0.45 5.64568343E8 -2.34E7 -0.53 -0.0573 -0.0829